LOCUS       DBEJAU010000001       153709 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC323 isolate 683620
            SAMN38261939-rid24807223.denovo.001, whole genome shotgun sequence.
ACCESSION   DBEJAU010000001 DBEJAU010000000
VERSION     DBEJAU010000001.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261939
            Sequence Read Archive: SRR26833919
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 153709)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 153709)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576303.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576303.1
            Genome Coverage       :: 154x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/19/2025 01:05:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,121
            CDSs (total)                      :: 2,078
            Genes (coding)                    :: 1,943
            CDSs (with protein)               :: 1,943
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 36
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 72 of 135
            Pseudo Genes (incomplete)         :: 63 of 135
            Pseudo Genes (internal stop)      :: 51 of 135
            Pseudo Genes (multiple problems)  :: 46 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..153709
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261939-rid24807223.denovo.001"
                     /strain="GPSC323"
                     /isolate="683620"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            62..541
                     /locus_tag="ACL29Z_000001"
                     /pseudo
     CDS             62..541
                     /locus_tag="ACL29Z_000001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677118.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
     gene            706..1005
                     /locus_tag="ACL29Z_000002"
     CDS             706..1005
                     /locus_tag="ACL29Z_000002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000767202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1827 family protein"
                     /protein_id="HGR0068395.1"
                     /translation="MKLINTTNSHSQLVKSQLESTDATLVEVYSAGNTDVIFTQAPLH
                     YEILISNKHRAIREPEIETIQEFFLKRKIDKTSVDEANIKTLYSEKLIGISIPIK"
     gene            1335..1589
                     /gene="tnpB"
                     /locus_tag="ACL29Z_000003"
     CDS             1335..1589
                     /gene="tnpB"
                     /locus_tag="ACL29Z_000003"
                     /inference="COORDINATES: protein motif:HMM:NF017528.4"
                     /note="TnpB, as the term is used for proteins encoded by
                     IS66 family insertion elements, is considered an accessory
                     protein, since TnpC, encoded by a neighboring gene, is a
                     DDE family transposase; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS66 family insertion sequence element accessory
                     protein TnpB"
                     /protein_id="HGR0068396.1"
                     /translation="MDSLAYVVKTHFELDSFSGQVFLFCGGRKDRFKTLYWDGQGFWL
                     LYKRFENGKLTWLSTEKDVKALAPEQVDWLMKGFSITPQI"
     gene            complement(2313..4040)
                     /gene="ezrA"
                     /locus_tag="ACL29Z_000004"
     CDS             complement(2313..4040)
                     /gene="ezrA"
                     /locus_tag="ACL29Z_000004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000064817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septation ring formation regulator EzrA"
                     /protein_id="HGR0068397.1"
                     /translation="MSNGQLIYLMVAIAVILVLAYVVAIFLRKRNEGRLEALEERKEE
                     LYNLPVNDEVEAVKNMHLIGQSQVAFREWNQKWVDLSLNSFADIENNLFEAEGYNHSF
                     RFLKTSHQIDQIESQITLIEEDIAAIRNALADLEKQESKNSGRVLHALDLFEELQHRV
                     AENSEQYGQALDEIEKQLENIQSEFSQFVTLNSSGDPVEAAVILDNTENHILALSHIV
                     DRVPALVTTLSTELPDQLQDLEAGYRKLIDANYHFVETDIEARFHLLYEAFKKNQENI
                     RQLELDNAEYENGQAQEEINALYDIFTREIAAQKVVENLLATLPTYLQHMKENNTLLG
                     EDIARLNKTYLLPETAASHVRRIQTELESFEAAIVEVTSNQEEPTQAYSVLEENLEDL
                     QTQLKDIEDEQISVSERLTQIEKDDINARQKANVYVNRLHTIKRYMEKRNLPGIPQTF
                     LKLFFTASNNTEDLMVELEQKMINIESVTRVLEIATNDMEALETETYNIVQYATLTEQ
                     LLQYSNRYRSFDERIQEAFNEALDIFEKEFDYHASFDKISQALEVAEPGVTNRFVTSY
                     EKTRETIRF"
     gene            complement(4122..6068)
                     /gene="gyrB"
                     /locus_tag="ACL29Z_000005"
     CDS             complement(4122..6068)
                     /gene="gyrB"
                     /locus_tag="ACL29Z_000005"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002283665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005694 - chromosome [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003918 - DNA topoisomerase type II
                     (double strand cut, ATP-hydrolyzing) activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006265 - DNA topological change [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase (ATP-hydrolyzing) subunit B"
                     /protein_id="HGR0068398.1"
                     /translation="MTEEIKNLQAQDYDASQIQVLEGLEAVRMRPGMYIGSTSKEGLH
                     HLVWEIVDNSIDEALAGFASHIQVFIEPDDSITVVDDGRGIPVDIQEKTGRPAVETVF
                     TVLHAGGKFGGGGYKVSGGLHGVGSSVVNALSTQLDVHVHKNGKIHYQEYRRGHVVAD
                     LEIVGDTDKTGTTVHFTPDPKIFTETTIFDFDKLNKRIQELAFLNRGLQISITDKREG
                     LEQTKHYHYEGGIASYVEYINENKDVIFDTPIYTDGEMDDITVEVAMQYTTGYHENVM
                     SFANNIHTHEGGTHEQGFRTALTRVINDYARKNKLLKDNEDNLTGEDVREGLTAVISV
                     KHPNPQFEGQTKTKLGNSEVVKITNRLFSEAFSDFLMENPQIAKRIVEKGILAAKARV
                     AAKRAREVTRKKSGLEISNLPGKLADCSSNNPAETELFIVEGDSAGGSAKSGRNREFQ
                     AILPIRGKILNVEKASMDKILANEEIRSLFTAMGTGFGAEFDVSKARYQKLVLMTDAD
                     VDGAHIRTLLLTLIYRYMKPILEAGYVYIAQPPIYGVKVGSEIKEYIQPGADQEIKLQ
                     EALARYSEGRTKPTIQRYKGLGEMDDHQLWETTMDPEHRLMARVSVDDAAEADKIFDM
                     LMGDRVEPRREFIEENAVYSTLDV"
     gene            complement(6083..6646)
                     /locus_tag="ACL29Z_000006"
     CDS             complement(6083..6646)
                     /locus_tag="ACL29Z_000006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HGR0068399.1"
                     /translation="MKYHDYIWDLGGTLLDNYETSTAAFVETLALYGITQDHDSVYQA
                     LKVSTPFAIETFAPNLENFLEKYKENEARELEHPILFEGVSDLLEVISNQGGRHFLVS
                     HRNDQVLEILEKTSIAAYFTEVVTSSSGFKRKPNPESMLYLREKYQISSGLVIGDRPI
                     DIEAGQAAGLDTHLFTSIVNLRQVLDI"
     gene            complement(6731..7285)
                     /locus_tag="ACL29Z_000007"
     CDS             complement(6731..7285)
                     /locus_tag="ACL29Z_000007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DJ-1 family glyoxalase III"
                     /protein_id="HGR0068400.1"
                     /translation="MVKVAVILAQGFEEIEALTVVDVLRRANITCDMVGFEEQVTGSH
                     AIQVRADHVFDGDLSDYDMIVLPGGMPGSAHLRDNQTLIQELQSFEQEGKKLAAICAA
                     PIALNQAEILKNKRYTCYDGVQEQILDGHYVKETVVVDGQLTTSRGPSTALAFAYELV
                     EQLGGDAESLRTGMLYQDVFGKNQ"
     gene            complement(7296..8519)
                     /locus_tag="ACL29Z_000008"
     CDS             complement(7296..8519)
                     /locus_tag="ACL29Z_000008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000830656.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA];
                     GO_process: GO:0051301 - cell division [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FtsW/RodA/SpoVE family cell cycle protein"
                     /protein_id="HGR0068401.1"
                     /translation="MKRSLDSRVDYSLLLPVFFLLVIGVVAIYIAVSHDYPNNILPIL
                     GQQVAWIALGLVIGFVVMLFNTEFLWKVTPFLYILGLGLMILPIVFYNPSLVASTGAK
                     NWVSINGITLFQPSEFMKISYILMLARVIVQFTKKHKEWRRTVPLDFLLIFWMILFTI
                     PVLVLLALQSDLGTALVFVAIFSGIVLLSGVSWKIIIPVFVTAVTGVAGFLAIFISKD
                     GRAFLHQIGMPTYQINRILAWLNPFEFAQTTTYQQAQGQIAIGSGGLFGQGFNASNLL
                     IPVRESDMIFTVIAEDFGFIGSVLVIALYLMLIYRMLKITLKSNNQFYTYISTGLIMM
                     LLFHIFENIGAVTGLLPLTGIPLPFISQGGSAIISNLIGVGLLLSMSYQTNLAEEKSG
                     KVPFKRKKVVLKQIK"
     gene            complement(8556..11006)
                     /locus_tag="ACL29Z_000009"
     CDS             complement(8556..11006)
                     /locus_tag="ACL29Z_000009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA];
                     GO_function: GO:0004386 - helicase activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008408 - 3'-5' exonuclease activity
                     [Evidence IEA];
                     GO_process: GO:0006139 - nucleobase-containing compound
                     metabolic process [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional DnaQ family
                     exonuclease/ATP-dependent helicase"
                     /protein_id="HGR0068402.1"
                     /translation="MKTIGNRYVVVDLEATSTGSKAKIIQVGIVVIEDGEIVDHYTTD
                     VNPHEPLDAHIKELTGLTDQRLAQAPDFSQVARKIFDLVEDGIFVAHNVQFDANLLAE
                     NLFFEGYELRNPRVDTVELAQVFFPELEKYSLPILCRELGIPLKHAHTALSDAQATAE
                     LLLFLLEKMTQLPKGLLERLLEMADALLYESYLVIEETYRNQSILSSPDLVQVQGLYF
                     KKTAASLEPRKLSQDFSKNISLLNLEVREEQESFAKEVGLLLKDEPVSLIQAPTGIGK
                     TYGYLLPALSQSKERQIVLSVPTKILQNQIMEEEGKRLKEVFHTDIHSLKGPQNYLKL
                     DAFYHSLQENDENRLFRRFKMQVLVWLTETETGDLDEIGQLYRYQHFLADLRHDGNLS
                     SQSLFVTEDFWKRSQERAETCKLLVTNHAYLVTRLEDNPEFVSDRLLIIDEVQKILLA
                     LENLLQETYDIQSIIDLIDKALVGEENRVQQRILESIRFECLYLIEQFQSGKSRKNIL
                     DSLDNLHQYFSELEVEGFDELVRYFTAEGDYWLEVTETSQKKIQISSTKSCRTLLSSL
                     LPESCQVLGVSATLEISQRVSLADLLGYPEAKFVKIESRGKQEQEVVMVKDFPLVTET
                     SLEVYAREVAALLVEIQAFQQPILVLFTAKDMLLAVSDLLTVSHLAQYKNGDVHQLKK
                     RFEKGEQQILLGAASFWEGVDFSSHPFVIQVVPRLPFQNPQEPLTKKINQELNQEGKN
                     AFYDYQLPMAIIRLKQALGRSMRREYQRSLTLILDRRIIGKRYGKQIVASLAEEATIK
                     TISRSEVDEAIDRFFNEL"
     gene            complement(11205..12134)
                     /locus_tag="ACL29Z_000010"
     CDS             complement(11205..12134)
                     /locus_tag="ACL29Z_000010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006154193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase U32 family protein"
                     /protein_id="HGR0068403.1"
                     /translation="MEKIVITATAESIEQVEQLLEAGVDRIYVGEKDFGLRLPTTFSY
                     DQLREIAKLVHDAGKELIVAVNALMHQDMMDRIKPFLDFLEEIKTDYITIGDAGVFYV
                     VNRDSYSFKTIYDASTMVTSSRQINFWGQKAGASEAVLAREIPSAELFKMPEILEIPA
                     EVLVYGASVIHHSKRPLLQNYYNFTHIDDEKTHKRDLFLAEPSDPESHYSIFEDNHGT
                     HIFANNDLDLMIKLTELVEHGFTRWKLEGLYTPGQNFVEIAKLFIQARSLIQEGNFSH
                     DQAFLLDEEVRKLHPKNRFLDTGFYDYDPDMVK"
     gene            12274..12561
                     /locus_tag="ACL29Z_000011"
     CDS             12274..12561
                     /locus_tag="ACL29Z_000011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001145225.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3270 domain-containing protein"
                     /protein_id="HGR0068404.1"
                     /translation="MPVRKLQSYEVDYQEELNQQLPHYQAYTPEAQSDANLKEILFFI
                     NIAVFCICIAIFSFIFLALKLSTALAFAAAIGFSLLVLKVQRSIIKRKRRR"
     gene            complement(12595..13929)
                     /gene="ciaH"
                     /locus_tag="ACL29Z_000012"
     CDS             complement(12595..13929)
                     /gene="ciaH"
                     /locus_tag="ACL29Z_000012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000491790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system sensor histidine kinase
                     CiaH"
                     /protein_id="HGR0068405.1"
                     /translation="MFSKLKKTWYADDFSYFIRNFGVFTLIFSTMTLIILQVMHSSLY
                     TSVDDKLHGLSENPQAVIQLAINRATEEIKDLENARADASKVEIKPNVSSNTEVILFD
                     KDFTQLLSGNRFLGLDKIKLEKKELGHIYQIQVFNSYGQEEIYRVILMETNISSVSTN
                     IKYAAVLINTSQLEQASQKHEQLIVVVMASFWILSLLASLYLARVSVRPLLESMQKQQ
                     SFVENASHELRTPLAVLQNRLETLFRKPEATIMDVSESIASSLEEVRNMRFLTTSLLN
                     LARRDDGIKPELAEVPTSFFNTTFTNYEMIASENNRVFRFENRIHRTIVTDQLLLKQL
                     MTILFDNAVKYTEEDGEIDFLISATDRNLYLLVSDNGIGISTEDKKKIFDRFYRVDKA
                     RTRQKGGFGLGLSLAKQIVDALKGTVTVKDNKPKGTIFEVKIAIQTPSKKKK"
     gene            complement(13919..14593)
                     /gene="ciaR"
                     /locus_tag="ACL29Z_000013"
     CDS             complement(13919..14593)
                     /gene="ciaR"
                     /locus_tag="ACL29Z_000013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004256510.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system response regulator CiaR"
                     /protein_id="HGR0068406.1"
                     /translation="MIKILLVEDDLGLSNSVFDFLDDFADVMQVFDGEEGLYEAESGV
                     YDLILLDLMLPEKNGFQVLKELREKGITTPVLIMTAKESLDDKGHGFELGADDYLTKP
                     FYLEELKMRIQALLKRSGKFNENTLTYGNIVVNLSTNTVKVEDTPVELLGKEFDLLVY
                     FLQNQNVILPKTQIFDRLWGFDSDTTISVVEVYVSKVRKKLKGTTFAENLQTLRSVGY
                     LLKDVQ"
     gene            complement(14702..17248)
                     /locus_tag="ACL29Z_000014"
     CDS             complement(14702..17248)
                     /locus_tag="ACL29Z_000014"
                     /EC_number="3.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001149089.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004177 - aminopeptidase activity
                     [Evidence IEA];
                     GO_function: GO:0008237 - metallopeptidase activity
                     [Evidence IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="M1 family metallopeptidase"
                     /protein_id="HGR0068407.1"
                     /translation="MQAVEHFIKQFVPEHYDLFLDLSRETKTFSGKVTITGQAQSDRI
                     SLHQKDLEITSVEVAGQARPFTVDHDNEALHIELAEAGQVELVLAFSGKITDNMTGIY
                     PSYYTVDGVKKEVLSTQFESHFAREAFPCVDEPEAKATFDLSLRFDQAEGELALSNMP
                     EIDVENRKETGIWKFETTPRMSSYLLAFVAGDLQGVTAKTKNGTLVGVYSTKAHPLSN
                     LDFSLDIAVRSIEFYEDYYGVKYPIPQSLHIALPDFSAGAMENWGLVTYREVYLVVDE
                     NSTFASRQQVALVVAHELAHQWFGNLVTMKWWDDLWLNESFANMMEYVCVDTIEPSWN
                     IFEDFQTGGVPLALERDATDGVQSVHVEVKHPDEINTLFDGAIVYAKGSRLMHMLRRW
                     LGDADFAKGLHAYFEKHQYSNTIGSDLWDALGQASGRDVAAFMDSWLEQPGYPVLTVK
                     VENDVLKISQKQFFIGENEDKNRLWVVPLNSNWKGLPDTLETESIEIPGYAALLAENE
                     GALRLNTENTAHYITDYQGDLLEAVLAELETLDNTSKLQIVQERRLLAEAGHISYADL
                     LPVLDKLAKEESYLVVSAVSQVISALERFIDEGTDAETAFKGLVAKLARHNYDRLGFE
                     AKDGESDEDELVRQLAVSMMIRSNDAEARQVASQIFATHKENLAELPAAIRSQVLINE
                     MKHHETKDLLALYLDTYTHATDAVFKRQLAAALAYSTDADNIQNLITSWKDKFVVKPQ
                     DLSAWYYQFLAHQATQKTAWSWARENWAWIKAALGGDMSFDSFVILPAHVFKTQQRLA
                     EYKEFFELQLSDLALSRNIGMGIKEIAARVDLISREKAAVEAVVLQYGNA"
     gene            complement(17371..17811)
                     /locus_tag="ACL29Z_000015"
     CDS             complement(17371..17811)
                     /locus_tag="ACL29Z_000015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012512572.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ASCH domain-containing protein"
                     /protein_id="HGR0068408.1"
                     /translation="MIPQEMWNKYKQINPLIGDEIDAWAFGVEPDLLADLVFKGEKTA
                     TASAYDLYVLEDEPLPQVGTFDIILDSQNQSVCIVEITKVSVELFNQVSAQHAFKEGE
                     GDKSLAYWRQVHEDFFTDCLGEVGLTFTPESKVVLEEFRKVYPL"
     gene            complement(17786..18655)
                     /locus_tag="ACL29Z_000016"
     CDS             complement(17786..18655)
                     /locus_tag="ACL29Z_000016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016772 - transferase activity,
                     transferring phosphorus-containing groups [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="putative PEP-binding protein"
                     /protein_id="HGR0068409.1"
                     /translation="MRNQLALSGEKILEKIYPQLFHHVGMIRGEYLLRELNQNIILAS
                     CQQFVKDYLETICSLYSDEEVWYRFSELTNTEANCLVGTREFFDEGHPLFGYRGTRRL
                     LACLDEFQAEAHVVTEVYQTNPNLSVIFPFVNDADQLKQAITVLRQQGFTGKVGTMIE
                     LPSAYFDLSSILETGISKIVVGMNDLTSFVFATMRNSQWHDMESPIMLDMLRDMQDKA
                     RKNKIDFAVAGYLNTSFIQKMNQLGIKCIIHYSSIPEIFDLEIDHPDHLKHIKEESKK
                     LQRSTHDTARNVE"
     gene            complement(18633..19133)
                     /locus_tag="ACL29Z_000017"
     CDS             complement(18633..19133)
                     /locus_tag="ACL29Z_000017"
                     /EC_number="3.6.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000403615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HGR0068410.1"
                     /translation="MEIKKHFGVYAVCLENGKLLCIEKARGPYQHRYDLPGGSQQLGE
                     GLTETLTREVMEETGFTVISYSNPRIYDVFVREELTNFMVHHVMALYDVEMNESAPQV
                     TTSEAVSDGANDSLGYIWMDIQEITEENASPLVLKVKSELLGFPELDKTSYMNWKVND
                     EKSTCP"
     gene            complement(19144..19842)
                     /locus_tag="ACL29Z_000018"
     CDS             complement(19144..19842)
                     /locus_tag="ACL29Z_000018"
                     /EC_number="1.1.1.100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006151199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="3-oxoacyl-ACP reductase"
                     /protein_id="HGR0068411.1"
                     /translation="MTKRVLITGVSSGIGLAQARLFLEKGYQVYGVDQGEKPLLEGDF
                     HFLQRDLTLDLEPIFDWCPQVDVLCNTAGVLDDYKPLLEQTAQDIQEIFEINYIIPVE
                     LTRYYLTQMLENKKGIIINMCSIASSLAGGGGHAYTSSKHALAGFTKQLALDYAEAGI
                     QVFGIAPGAVKTAMTAADFEPGGLADWVASETPIKRWIEPEEIAELSLFLASGKASAM
                     QGQILTIDGGWSLK"
     gene            complement(19835..20071)
                     /locus_tag="ACL29Z_000019"
     CDS             complement(19835..20071)
                     /locus_tag="ACL29Z_000019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018367459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2829 domain-containing protein"
                     /protein_id="HGR0068412.1"
                     /translation="MTFEEILPGLKAKKKYVRTGWGGAENYVQLFDTIEQNGLALEMT
                     PYFLINVSGEGEGFSMWSPTACDVLATDWVEVHD"
     gene            complement(20171..21097)
                     /locus_tag="ACL29Z_000020"
     CDS             complement(20171..21097)
                     /locus_tag="ACL29Z_000020"
                     /EC_number="1.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001269463.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase family oxidoreductase"
                     /protein_id="HGR0068413.1"
                     /translation="MRYITLGQDDKELSEIVLGMMRIKDKSVKEVEELVETALSVGIN
                     AFDLADIYGRGRCEELLGLVLKNRPDLREKMWIQSKCGIRIEEFTYFDFSKDYIIKSV
                     DGILQRLKIDHLDSLLLHRPDALMESDQVAEAFDLLYKQGKVRDFGVSNQNPMMMELL
                     KKDVKQPLAVNQLQLSAAFTPGFESAFHVNMEDSQAAMRDGSIFEYCKLHDVVIQAWS
                     VLQFGYFKGNFVGNEKFQALNQVLDRLAIKYGVTSSTIAISWILRYPAKMQAVVGTTN
                     PKHLREVSQAANFSLTRKEWYEIYLAAGNNLP"
     gene            complement(21172..21987)
                     /locus_tag="ACL29Z_000021"
     CDS             complement(21172..21987)
                     /locus_tag="ACL29Z_000021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0068414.1"
                     /translation="MKKMKYYEETSALLHEFSEENQKYFEELWESFNLAGFLYDEDYL
                     REQIYLMMLDFSEAERDGMSAEDYLGKNPKKIMKEILKGAPRSSIKESLLTPILILAV
                     LRYYQLLSDFSKGPLLTVNLLTFLGQLLIFLIGFGLVATILRWCLVQDSPKMKIGTYI
                     VVGILVLLVVMGYVGIGSFVQEGAFYIPAPWDSLSVFTISLVIGIWNWKEAVFRPFVS
                     MIIAHLVVGSLLRYYEWMGISNVFLTKVIPLAVLFIGIFVLFRGFKKIKWSEV"
     gene            complement(21991..22311)
                     /locus_tag="ACL29Z_000022"
     CDS             complement(21991..22311)
                     /locus_tag="ACL29Z_000022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000665424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HGR0068415.1"
                     /translation="MKETQLLKGVLEGCVLDMIGQKERYGYELVQTLREAGFDTIVPG
                     TIYPLLQKLEKNQWIRGDMRPSPDGPDRKYFSLMKEGEERVSVFWQQWDDLSQKVEGI
                     KNGG"
     gene            complement(22401..22637)
                     /locus_tag="ACL29Z_000023"
     CDS             complement(22401..22637)
                     /locus_tag="ACL29Z_000023"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0068416.1"
                     /translation="MKIKEQTRKLAAGCSKHCFEVVDRTDEVSSKHVFEVVDETDEVS
                     SKHCFEVVDETDEVSNHTYGRATLTWFEEIFEEY"
     gene            complement(22689..24686)
                     /gene="metG"
                     /locus_tag="ACL29Z_000024"
     CDS             complement(22689..24686)
                     /gene="metG"
                     /locus_tag="ACL29Z_000024"
                     /EC_number="6.1.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006155678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000049 - tRNA binding [Evidence IEA];
                     GO_function: GO:0004825 - methionine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006431 - methionyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="methionine--tRNA ligase"
                     /protein_id="HGR0068417.1"
                     /translation="MSEKNFYITTPIYYPSGKLHIGSAYTTIACDVLARYKRLMGYDV
                     FYLTGLDEHGQKIQQKAEEAGITPQAYVDGMAVGVKELWQLLDISYDKFIRTTDDYHE
                     KVVAQVFERLLAQDDIYLGEYSGWYSVSDEEFFTESQLAEVFRDEAGNVTGGIAPSGH
                     EVEWVSEESYFLRLSKYQDRLVEFFKSHPEFITPDGRLNEMLRNFIEPGLEDLAVSRT
                     TFTWGVPVPSNPKHVVYVWIDALLNYATALGYGQDEHGNFDKFWNGTVFHMVGKDILR
                     FHSIYWPILLMMLDVKLPDRLIAHGWFVMKDGKMSKSKGNVVYPEMLVERYGLDPLRY
                     YLMRSLPVGSDGTFTPEDYVGRINYELANDLGNLLNRTVSMINKYFDGQIPAYVEGVT
                     EFDNALAEVAEQSIADYHTHMEAVDYPRALEAVWTLISRTNKYIDETAPWVLAKDEAL
                     RDQLASVMSHLAASLRVVAHLIEPFMMETSRAVLTQLGLDEVASLENLSLADFPADVT
                     VVAKGTPIFPRLDMEEEIAYIKEQMEGNKPAVEKEWNPDEVELKLNKDEIKFEDFDKV
                     EIRVAEVKEVSKVEASDKLLQFRLDAGDGEDRQILSGIAKYYPNEQELVGKKVQIVAN
                     LKPRKMMKKYVSQGMILSAEHDGKLTLLTVDPAVPNGSVIG"
     gene            complement(24810..26069)
                     /locus_tag="ACL29Z_000025"
     CDS             complement(24810..26069)
                     /locus_tag="ACL29Z_000025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001180420.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HGR0068418.1"
                     /translation="MQNLKFAFSSIMAHKMRSLLTMIGIIIGVSSVVVIMALGDSLSR
                     QVNKDMTKSQKNISVFFSPKKSKDGSFTQKQSAFTVSGKEEEVPVEPPKPQESWVQEA
                     AKLKGVDSYYVTNSTNAILTYQDKKVENANLTGGNRTYMDAVKNEIIAGRSLREQDFK
                     EFASVILLDEELSISLFESPQEAINKVVEVNGFSYRVIGVYTSPEAKRSKIYGFGGLP
                     ITTNISLAANFNIDEIASIVFRVNDTSLTPTLGPELARKMTELAGLQQGEYQVADESV
                     VFAEIQQSFSFMTTIISSIAGISLFVGGTGVMNIMLVSVTERTREIGLRKALGATRAN
                     ILIQFLIESMILTLLGGLIGLTIASGLTALAGLLLQGLIEGIEVGVSIPVALFSLAVS
                     ASVGMIFGVLPANKASKLDPIEALRYE"
     gene            complement(26071..26772)
                     /locus_tag="ACL29Z_000026"
     CDS             complement(26071..26772)
                     /locus_tag="ACL29Z_000026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016465646.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGR0068419.1"
                     /translation="MKQLISLKNIFRSYRNGDQELQVLKNINLEVNEGEFVAIMGPSG
                     SGKSTLMNTIGMLDTPTSGEYYLEGQEVAGLGEKQLAKVRNQQIGFVFQQFFLLSKLN
                     ALQNVELPLIYAGVSSSKRRKLAEEYLDKVELTERSHHLPSELSGGQKQRVAIARALV
                     NNPSIILADEPTGALDTKTGNQIMQLLVDLNKEGKTIIMVTHEPEIAAYAKRQIVIRD
                     GVISSDSAQLGKEEN"
     gene            complement(26756..27955)
                     /locus_tag="ACL29Z_000027"
     CDS             complement(26756..27955)
                     /locus_tag="ACL29Z_000027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000728654.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_function: GO:0042802 - identical protein binding
                     [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="efflux RND transporter periplasmic adaptor
                     subunit"
                     /protein_id="HGR0068420.1"
                     /translation="MKKKNGKAKKWQLYAAIGAASVVVLGAGGILLFRQPSQTALKDE
                     PTHLVVAKEGSVASSVLLSGTVTAKNEQYVYFDASKGDLDEILVSVGDKVSEGQALVK
                     YSSSEAQAAYDSASRAVARADRHINELNQARNEAASAPAPQLPAPVGGEDATVQSPTP
                     VAGNSVASIDAQLGDARDARADAAAQLSKAQSQLDATTVLSTLEGTVVEVNSNVSKSP
                     TGASQVMVHIVSNENLQVKGELSEYNLANLSVGQEVSFTSKVYPDKKWTGKLSYISDY
                     PKNNGEAASPAAGNNTGSKYPYTIDVTGEVGDLKQGFSVNIEVKSKTKAILVPVSSLV
                     MDDSKNYVWIVDEQQKSKKVEVSLGNADAENQEITSGLTNGAKVISNPTSSLEEGKEV
                     KADEATN"
     gene            28241..29587
                     /gene="gor"
                     /locus_tag="ACL29Z_000028"
     CDS             28241..29587
                     /gene="gor"
                     /locus_tag="ACL29Z_000028"
                     /EC_number="1.8.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015511376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004362 - glutathione-disulfide reductase
                     (NADPH) activity [Evidence IEA];
                     GO_function: GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA];
                     GO_function: GO:0050661 - NADP binding [Evidence IEA];
                     GO_process: GO:0006749 - glutathione metabolic process
                     [Evidence IEA];
                     GO_process: GO:0045454 - cell redox homeostasis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione-disulfide reductase"
                     /protein_id="HGR0068421.1"
                     /translation="MREYDIIAIGGGSGGIATMNRAGEHGAKAAVIEEKKLGGTCVNV
                     GCVPKKIMWYGAQIAETFHQFGEDYGFKTTDLNFDFATLRRNREAYIDRARSSYDGSF
                     KRNGVDLIEGHAEFVDSHTVSVNGELIRAKHIVIATGAHPSIPNIPGAELGGSSDDVF
                     AWEELPESVAILGAGYIAVELAGVLHTFGVKTDLFVRRDRPLRGFDSYIVEGLVKEME
                     RINLPLHTHKVPAKLEKTAKGITIHFEDGTSHTASQVIWATGRRPNVKGLQLEKAGVT
                     LNERGFIQVDEYQNTVVEGIYALGDVTGEKELTPVAIKAGRTLSERLFNGKTTAKMDY
                     SAIPTVVFSHPAIGTVGLTEEQAIKEYGQDQIKVYKSSFTSMYSACTRNRQESRFKLI
                     TAGSEEKVVGLHGIGYGVDEMIQGFAVAIKMGATKADFDATVAIHPTSSEEFVTMR"
     gene            29784..30320
                     /locus_tag="ACL29Z_000029"
     CDS             29784..30320
                     /locus_tag="ACL29Z_000029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000709035.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biotin transporter BioY"
                     /protein_id="HGR0068422.1"
                     /translation="MKKAHVYAIPAIGAALIAVLAQISLPIGPVPFTLQNFAIGLIAT
                     VFRPREAVLSAGLYLLLGAIGLPVFAGGGAGFQALVGPTAGYLWFYLVYSGLTSSLTN
                     SKSGVVKIFLANLLGDALVFVGGILSLHFLAGMAFEKALVVGVLPFIIPDLGKLLAIS
                     FISRPLLQRLKNQAYFTN"
     gene            30382..30528
                     /locus_tag="ACL29Z_000030"
     CDS             30382..30528
                     /locus_tag="ACL29Z_000030"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0068423.1"
                     /translation="MKIKEQTRKLAAGCSKHCFEVVDETDEVSNHTYGKAKLMRFEEI
                     FEEY"
     gene            complement(30525..30740)
                     /locus_tag="ACL29Z_000031"
     CDS             complement(30525..30740)
                     /locus_tag="ACL29Z_000031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000807422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdbC family protein"
                     /protein_id="HGR0068424.1"
                     /translation="MAEFTFEIEEHLLTLSENEKGWTKEINRVSFNGAPAKFDIRAWS
                     PDHTKMGKGITLSNEEFQTMVDAFKGN"
     gene            30838..31158
                     /locus_tag="ACL29Z_000032"
     CDS             30838..31158
                     /locus_tag="ACL29Z_000032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001216095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0068425.1"
                     /translation="MRHKFQQVLDKIHDFLNGHDQPDQTETNSLTATIEEAIQKQTAV
                     HLILSETSFTGDIIKYDQQGQQIIVKNFAKNVSRIIRISDIQRLRFVPSTVQTAQKNR
                     FKKE"
     gene            complement(31189..31527)
                     /locus_tag="ACL29Z_000033"
     CDS             complement(31189..31527)
                     /locus_tag="ACL29Z_000033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001196050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP cone domain-containing protein"
                     /protein_id="HGR0068426.1"
                     /translation="MQVIKRNGEIAEFNPDKIYQAILKAAQTVYVLTDDLRQNLAQVT
                     KKVVLDLQEAKVERATISMIQSMVEHRLLGAGYITIAEHYISYRLQRDLERSGYGDHI
                     AVHLHFEQIR"
     gene            complement(31539..32258)
                     /gene="trmD"
                     /locus_tag="ACL29Z_000034"
     CDS             complement(31539..32258)
                     /gene="trmD"
                     /locus_tag="ACL29Z_000034"
                     /EC_number="2.1.1.228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0052906 - tRNA
                     (guanine(37)-N1)-methyltransferase activity [Evidence
                     IEA];
                     GO_process: GO:0008033 - tRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (guanosine(37)-N1)-methyltransferase TrmD"
                     /protein_id="HGR0068427.1"
                     /translation="MKIDILTLFPEMFSPLEHSIVGKAREKGLLDIQYHNFRENAEKA
                     RHVDDDPYGGGQGMLLRAQPIFDSFDAIEKKNPRVILLDPAGKQFDQAYAEDLAQEEE
                     LIFICGHYEGYDERIKTLVTDEISLGDYVLTGGELAAMTMIDATVRLIPEVIGKESSH
                     QDDSFSSGLLEYPQYTRPYDYRGMVVPDVLMSGHHEKIRQWRLYESLKKTYERRPDLL
                     EHYQLTVEEEKMLAEIKENKE"
     gene            complement(32248..32766)
                     /gene="rimM"
                     /locus_tag="ACL29Z_000035"
     CDS             complement(32248..32766)
                     /gene="rimM"
                     /locus_tag="ACL29Z_000035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016465641.1"
                     /note="Essential for efficient processing of 16S rRNA;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0043022 - ribosome binding [Evidence IEA];
                     GO_process: GO:0006364 - rRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome maturation factor RimM"
                     /protein_id="HGR0068428.1"
                     /translation="MNYFNVGKIVNTQGLQGEMRVLSVTDFAEERFKKGAELALFDEK
                     DQFVQTVTIASHRKQKNFDIIKFKDMYHINTIEKYKGYSLKVAEEDLNDLDDGEFYYH
                     EIIGLEVYEGDSLVGTIKEILQPGANDVWVVKRKGKRDLLLPYIPPVVLNVDIPNKRV
                     DVEILEGLDDED"
     gene            complement(32797..33585)
                     /locus_tag="ACL29Z_000036"
     CDS             complement(32797..33585)
                     /locus_tag="ACL29Z_000036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000819180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HGR0068429.1"
                     /translation="MKRFEVSTEIGSLSVTYQKQKKVLVCLNGAGLLPSYENFSLILE
                     KPPPTIGYLTIDFPNTGRSPIHDQAGKNLDNLADAVYEVLEELGISEYILCAHSWSGI
                     LACKLLEKPIKRQTLVAIEPTTKKVMFADFSENPYPKMEEQMRLIDECGPELYFKNLT
                     QATFSPETNKKIWELMQEKGLELENQDPEFQISGEITEEDFENLSIESHVPVFIFCQT
                     YREKEYRESEYWTSNTKLILGGNHHYLQWSESEKIAAIIRELSE"
     gene            complement(33689..33974)
                     /locus_tag="ACL29Z_000037"
                     /pseudo
     CDS             complement(33689..33974)
                     /locus_tag="ACL29Z_000037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000654120.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="MazG nucleotide pyrophosphohydrolase
                     domain-containing protein"
     gene            complement(34162..34401)
                     /gene="kphA"
                     /locus_tag="ACL29Z_000038"
     CDS             complement(34162..34401)
                     /gene="kphA"
                     /locus_tag="ACL29Z_000038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005590445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding protein KphA"
                     /protein_id="HGR0068430.1"
                     /translation="MDTIENLIIAIVKPLISQPDALTIKIEDTPEFLEYHLNLDQSDV
                     GRVIGRKGRTISAIRTIVYSVPTEYKKVRIVIDEK"
     gene            complement(34421..34693)
                     /gene="rpsP"
                     /locus_tag="ACL29Z_000039"
     CDS             complement(34421..34693)
                     /gene="rpsP"
                     /locus_tag="ACL29Z_000039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002884675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0000314 - organellar small ribosomal
                     subunit [Evidence IEA];
                     GO_component: GO:0022627 - cytosolic small ribosomal
                     subunit [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S16"
                     /protein_id="HGR0068431.1"
                     /translation="MAVKIRLTRMGSKKKPFYRINVADSRSPRDGRFIETVGTYNPLV
                     AENQVTLKEDRVLAWLANGAQPSDTVRNILSKEGVLKKFHDSKFSK"
     gene            34863..35072
                     /locus_tag="ACL29Z_000040"
     CDS             34863..35072
                     /locus_tag="ACL29Z_000040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000953868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0068432.1"
                     /translation="MLSVNTILEKFYKEHQVKPFISPERELDTWLLSPKPVPKRNMDL
                     LVDDSLAGDIILLWRIQFGTFTTET"
     gene            35551..35763
                     /locus_tag="ACL29Z_000041"
     CDS             35551..35763
                     /locus_tag="ACL29Z_000041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0068433.1"
                     /translation="MSFYGLFYNGIAITPNTYLSAWFVNFIAALPLNFLIVEPIARFI
                     LSSFQKPFTGEEVEDFQDDDEIPTII"
     gene            35847..36650
                     /locus_tag="ACL29Z_000042"
     CDS             35847..36650
                     /locus_tag="ACL29Z_000042"
                     /EC_number="5.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000731914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003755 - peptidyl-prolyl cis-trans
                     isomerase activity [Evidence IEA];
                     GO_process: GO:0000413 - protein peptidyl-prolyl
                     isomerization [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HGR0068434.1"
                     /translation="MKKLATLLLLSTVALAGCSSVQRSLRGDDYVDSSLAAEESSKVA
                     AQSAKELNDALTNENANFPQLSKEVAEDEAEVILHTSQGDIRIKLFPKLAPLAVENFL
                     THAKEGYYNGITFHRVIDGFMVQTGDPKGDGTGGQSIWHDKDKTKDKGTGFKNEITPY
                     LYNIRGALAMANTGQPNTNGSQFFINQNSTDTSSKLPTSKYPQKIIEAYKEGGNPSLD
                     GKHPVFGQVIDGMDVVDKIAKAEKDEKDKPTTAITIDSIEVVKDYDFKS"
     gene            complement(36706..38247)
                     /locus_tag="ACL29Z_000043"
     CDS             complement(36706..38247)
                     /locus_tag="ACL29Z_000043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002918612.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HGR0068435.1"
                     /translation="MSILEVKNLSHGFGDRAIFEDVSFRLLKGEHIGLVGANGEGKST
                     FMSIVTGKMLPDEGKVEWSKYVTAGYLDQHSVLAERQSVRDVLRTAFDELFKAEARIN
                     DLYMKMAEDGADVDALMEEVGELQDRLESRDFYTLDAKIDEVARALGVMDFGMDTDVT
                     SLSGGQRTKVLLAKLLLEKPDILLLDEPTNYLDAEHIDWLKRYLQNYENAFVLISHDI
                     PFLNDVINIVYHVENQQLTRYSGDYYQFQEVYAMKKSQLEAAYERQQKEIADLKDFVA
                     RNKARVATRNMAMSRQKKLDKMDIIELQSEKPKPSFDFKPARTPGRFIFQAKNLQIGY
                     DRPLTKPLNLTFERNQKVAIIGANGIGKTTLLKSLLGIISPIAGEVERGDYLELGYFE
                     QEVEGGNRQTPLEAVWNAFPALNQAEVRAALARCGLTTKHIESQIQVLSGGEQAKVRF
                     CLLMNRENNVLVLDEPTNHLDVDAKDELKRALKEYRGSILMVCHEPDFYEGWIDQIWD
                     FNNLT"
     gene            complement(38249..38731)
                     /locus_tag="ACL29Z_000044"
     CDS             complement(38249..38731)
                     /locus_tag="ACL29Z_000044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000976721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanZ family protein"
                     /protein_id="HGR0068436.1"
                     /translation="MMKKTYNHILVWGVIFYSICIVCFCFTPQEQSTVGVGTPDIQHL
                     GRLVFLLTPFNSLWKLGEVSDIGQLCWIFLQNVLNVFLFFPLIFQLLYLFPNLRKTKK
                     VLLFSFLVSLGIECTQLILDFFFDFNRVFEIDDLWTNTLGGYLAWLLYKRLHKNKIRN
                     "
     gene            complement(38731..39816)
                     /gene="rlmN"
                     /locus_tag="ACL29Z_000045"
     CDS             complement(38731..39816)
                     /gene="rlmN"
                     /locus_tag="ACL29Z_000045"
                     /EC_number="2.1.1.192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000804770.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008757 - S-adenosylmethionine-dependent
                     methyltransferase activity [Evidence IEA];
                     GO_function: GO:0016433 - rRNA (adenine) methyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0030488 - tRNA methylation [Evidence IEA];
                     GO_process: GO:0070475 - rRNA base methylation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (adenine(2503)-C(2))-methyltransferase
                     RlmN"
                     /protein_id="HGR0068437.1"
                     /translation="MKPSIHSLVHQTMQEWVLEQGEKKFRADQIWEWLYRKRVQSFEE
                     MTNLSKDLIAKLNDQFVVNPLKQRIVQESADGTVKYLFELPDGMLIETVLMRQHYGLS
                     VCVTTQVGCNIGCTFCASGLIKKQRDLNNGEIVAQIMLVQKYFAERGQDERVSHIVVM
                     GIGEPFDNYNNVLNFFRTINDDKGMAISARHITVSISGLAHKIRDFADEGVQVNLAVS
                     LHAPNNELRSSIMKINRAFPIEKLFAAIEYYIETTNRRVTFEYIMLNEVNDGVEQALE
                     LAELLKNIKKLSYVNLIPYNPVSEHDQYSRSPKERVLAFYDTLKKKGVNCVVRQEHGT
                     DIDAACGQLRSNTMKRDRQKAVAAVNP"
     gene            complement(39837..40367)
                     /locus_tag="ACL29Z_000046"
     CDS             complement(39837..40367)
                     /locus_tag="ACL29Z_000046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522225.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YutD family protein"
                     /protein_id="HGR0068438.1"
                     /translation="MRKEIAPELYNYNKFPGPEFHLHGDKVETEGIAFSLVENIKDAF
                     DVTTFNQRFSEVLTKFDYIVGDWSNEQLRLRGFYKDDRTEEKLEKISRLQDYLLEYCS
                     YGCAYFVLENEAPKRASFDKKMRKTEEETPSRKGKKPTQTKRKSNADKKNRRRQKDQH
                     SQKEDKEQRHFVIRQK"
     gene            complement(40525..41130)
                     /gene="sodA"
                     /locus_tag="ACL29Z_000047"
     CDS             complement(40525..41130)
                     /gene="sodA"
                     /locus_tag="ACL29Z_000047"
                     /EC_number="1.15.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519814.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004784 - superoxide dismutase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="superoxide dismutase SodA"
                     /protein_id="HGR0068439.1"
                     /translation="MAIILPELPYAYDALEPYIDAETMHLHHDKHHQTYVNNANAALE
                     KHPEIGEDLEALLADVESIPADIRQALINNGGGHLNHALFWELMTPEKTAPSAELAAA
                     IDATFGSFEEFQAAFTAAATTRFGSGWAWLVVNKEGKLEVTSTANQDTPISEGKKPIL
                     GLDVWEHAYYVKYRNVRPDYIKAFFSVINWNKVDELYAAAK"
     gene            complement(41271..42308)
                     /gene="holA"
                     /locus_tag="ACL29Z_000048"
     CDS             complement(41271..42308)
                     /gene="holA"
                     /locus_tag="ACL29Z_000048"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001845438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit delta"
                     /protein_id="HGR0068440.1"
                     /translation="MLAIEESQKLTLSNLPSLSLFTGTDQGQFEVMKSQVLKQIGYDS
                     ADLNFAYFDMKEVVYKDVELELVSLPFFADEKIVILDYFMDITTAKKRFLTDDELKSF
                     EEYLDNPSPTTKLIIFAEGKLDSKRRLVKLLKRDAKAFDAVEVKEQELRQYFQKWSQK
                     QGLQFTNHSFENLLIKSGFQFSEIQKNLLFLQSYKADSVIEEEDIVNAIPKTLQDNIF
                     DLTQFILTKKMDQARDLVRDLTLQGEDEIKLIAVMLGQFRTFTQVKILAESGQTESQI
                     ASSLGSYLGRNPNPYQIKFALRDSRGLSLSFLKQAISYLIETDYQIKTGLYEKGFLFE
                     KALLQIASQVN"
     gene            complement(42342..43277)
                     /locus_tag="ACL29Z_000049"
     CDS             complement(42342..43277)
                     /locus_tag="ACL29Z_000049"
                     /EC_number="1.3.98.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004152 - dihydroorotate dehydrogenase
                     activity [Evidence IEA];
                     GO_process: GO:0006221 - pyrimidine nucleotide
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate oxidase"
                     /protein_id="HGR0068441.1"
                     /translation="MVSTKTQIAGFEFDNCLMNAAGVACMTIEELEEVKNSAAGTFVT
                     KTATLDFRQGNPEPRYQDVPLGSINSMGLPNNGLDYYLDYLLDLQEKESNRTFFLSLV
                     GMSPEETHTILKKVQESDFRGLTELNLSCPNVPGKPQIAYDFETTDRILAEVFAYFTK
                     PLGIKLPPYFDIVHFDQAAAIFNKYPLKFVNCVNSIGNGLYIEDESVVIRPKNGFGGI
                     GGEYIKPTALANVHAFYQRLNPQIQIIGTGGVLTGRDAFEHILCGASMVQVGTTLHKE
                     GVSAFDRITNELKAIMVEKGYESLEDFRGKLRYID"
     gene            complement(43830..45020)
                     /gene="metK"
                     /locus_tag="ACL29Z_000050"
     CDS             complement(43830..45020)
                     /gene="metK"
                     /locus_tag="ACL29Z_000050"
                     /EC_number="2.5.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000003937.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004478 - methionine adenosyltransferase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006556 - S-adenosylmethionine biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="methionine adenosyltransferase"
                     /protein_id="HGR0068442.1"
                     /translation="MSERKLFTSESVSEGHPDKIADQISDAILDAILAKDPEAHVAAE
                     TAVYTGSVHVFGEISTNAYVDINRVVRDTIAEIGYTNTEYGFSAETVGVHPSLVEQSP
                     DIAQGVNEALEVRGNADQDPLDLIGAGDQGLMFGFAVDETEELMPLPIALSHKLVRRL
                     AELRKSGEISYLRPDAKSQVTVEYDENDRPVRVDTVVISTQHDPEATNEQIHQDVIDK
                     VIKEVIPSSYLDDKTKFFINPTGRFVIGGPQGDSGLTGRKIIVDTYGGYSRHGGGAFS
                     GKDATKVDRSASYAARYIAKNIVAAGLAKKAEVQLAYAIGVAQPVSVRIDTFGTGTVA
                     ESQLEKAARQIFDLRPAGIIQMLDLKRPIYRQTSAYGHMGRTDIDLPWERLDKVDALK
                     EAVK"
     gene            complement(45235..46578)
                     /locus_tag="ACL29Z_000051"
     CDS             complement(45235..46578)
                     /locus_tag="ACL29Z_000051"
                     /EC_number="3.6.4.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004386 - helicase activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HGR0068443.1"
                     /translation="MSFTKFQFKNYIREALKELKFTTPTEVQDKLIPIVLAGRDLVGE
                     SKTGSGKTHTFLLPIFQQLDEASDSVQAVITAPSRELATQIYQVARQISAHSDVEVRV
                     VNYVGGTDKARQIEKLASNQPHIVIGTPGRIYDLVKSGDLAIHKAKTFVVDEADMTLD
                     MGFLETVDKIAGSLPKDLQFMVFSATIPQKLQPFLKKYLSNPVMEKIKTKTVISDTID
                     NWLISTKGHDKNAQIYQLTQLMQPYLAMIFVNTKTRADELHSYLTSQGLKVAKIHGDI
                     APRERKRIMNQVQNLDFEYIVATDLAARGIDIEGVSHVINDAIPQDLSFFVHRVGRTG
                     RNGLPGTAITLYQPSDDSDIRELEKLGIKFSPKMVKDGEFQDTYDRDRRANREKKQDK
                     LDIEMIGLVKKKKKKVKPGYKKKIQWAVDEKRRKTKRAENRARGRAERKAKRQTF"
     gene            complement(46718..47533)
                     /locus_tag="ACL29Z_000052"
     CDS             complement(46718..47533)
                     /locus_tag="ACL29Z_000052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398916.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease/exonuclease/phosphatase family
                     protein"
                     /protein_id="HGR0068444.1"
                     /translation="MKFLTLNTHSWMEKEAEEKFQILLEDILEKDYDLICFQEINQEM
                     TSSEVEVNDLYQALPAAEPIHQDHYVRLLVEKLSEQGKNYYWTWAYNHIGYNRYHEGV
                     AILSKTPIETREILVSDVDDPTDYHTRRVALAETVVDGKELAVASVHLSWWDKGFQEE
                     WARFEAVLKKLNKPLLLAGDFNNPAGQEGYQAILASPLGLQDAFEVAQEKSGSYTVPP
                     EIDGWKGNTEPLRIDYVFTTKELAVENLHVVFDGNKSPQVSDHYGLNAILNWK"
     gene            complement(47585..49765)
                     /locus_tag="ACL29Z_000053"
     CDS             complement(47585..49765)
                     /locus_tag="ACL29Z_000053"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000974069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015144 - carbohydrate transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit IIBC"
                     /protein_id="HGR0068445.1"
                     /translation="MMKDTFKNVLSFEFWQKFGKALMVVIAVMPAAGLMISIGKSIVM
                     INPTFAPLVITGGILEQIGWGVIGNLHILFALAIGGSWAKERAGGAFAAGLAFILINR
                     ITGTIFGVSGDMLKNPDAMVTTFFGGSIKVADYFISVLEAPALNMGVFVGIISGFVGA
                     TAYNKYYNFRKLPDALSFFNGKRFVPFVVILRSAIAAILLAAFWPVVQTGINNFGIWI
                     ANSQETAPILAPFLYGTLERLLLPFGLHHMLTIPMNYTALGGTYDILTGAAKGTQVFG
                     QDPLWLAWVTDLVNLKGTDASQYQHLLDTVHPARFKVGQMIGSFGILMGVIVAIYRNV
                     DADKKHKYKGMMIATALATFLTGVTEPIEYMFMFIATPMYLVYSLVQGAAFAMADVVN
                     LRMHSFGSIEFLTRTPIAISAGIGMDIVNFVWVTVLFAVIMYFIANFMIQKFNYATPG
                     RNGNYETAEGSEETSSEVKVAAGSQAVNIINLLGGRVNIVDVDACMTRLRVTVKDADK
                     VGNAEQWKAEGAMGLVMKGQGVQAIYGPKADILKSDIQDILDSGEIIPETLPSQMTEA
                     QQNTVHFKDLTEEVYSVADGQVVALEQVKDPVFAQKMMGDGFAVEPANGNIVSPVSGT
                     VSSIFPTKHAFGIVTEAGLEVLVHIGLDTVSLEGKPFTVHVAEGQKVTAGDLLVTADL
                     DAIRAAGRETSTVVVFTNGDAIKSVKLEKTGSLAAKTAVAKVEL"
     gene            complement(50051..50977)
                     /gene="ftsX"
                     /locus_tag="ACL29Z_000054"
     CDS             complement(50051..50977)
                     /gene="ftsX"
                     /locus_tag="ACL29Z_000054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="permease-like cell division protein FtsX"
                     /protein_id="HGR0068446.1"
                     /translation="MISRFFRHLFEALKSLKRNGWMTVAAVSSVMITLTLVAIFASVI
                     FNTAKLATDIENNVRVVVYIRKDVEDNSQTIEKEGQTVTNNDYHKVYDSLKNMSTVKS
                     VTFSSKEEQYEKLTEIMGDNWKIFEGDANPLYDAYIVEANTPNDVKTIAEDAKKIEGV
                     SEVQDGGANTERLFKLASFIRVWGLGIAALLIFIAVFLISNTIRITIISRSREIQIMR
                     LVGAKNSYIRGPFLLEGAFIGLLGAIAPSVLVFIVYQIVYQSVNKSLVGQNLSMISPD
                     LFSPLMIALLFVIGVFIGSLGSGISMRRFLKI"
     gene            complement(50970..51662)
                     /gene="ftsE"
                     /locus_tag="ACL29Z_000055"
     CDS             complement(50970..51662)
                     /gene="ftsE"
                     /locus_tag="ACL29Z_000055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012130521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0000910 - cytokinesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cell division ATP-binding protein FtsE"
                     /protein_id="HGR0068447.1"
                     /translation="MSIIEMRDVVKKYDNGTTALRGVSVSVQPGEFAYIVGPSGAGKS
                     TFIRSLYREVKIDKGSLSVAGFNLVKIKKKDVPLLRRSVGVVFQDYKLLPKKTVYENI
                     AYAMEVIGENRRNIKRRVMEVLDLVGLKHKVRSFPNELSGGEQQRIAIARAIVNNPKV
                     LIADEPTGNLDPDNSWEIMNLLERINLQGTTILMATHNSQIVNTLRHRVIAIENGRVV
                     RDESKGEYGYDD"
     gene            complement(51680..52775)
                     /gene="prfB"
                     /locus_tag="ACL29Z_000056"
     CDS             complement(join(51680..52702,52704..52775))
                     /gene="prfB"
                     /locus_tag="ACL29Z_000056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015511312.1"
                     /ribosomal_slippage
                     /note="programmed frameshift; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0016149 - translation release factor
                     activity, codon specific [Evidence IEA];
                     GO_process: GO:0006415 - translational termination
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 2"
                     /protein_id="HGR0068448.1"
                     /translation="MDISVIRQKIDANREKLASFRGSLDLEGLEEEIAILENKMTEPD
                     FWNDNIAAQKTSQELNELKNTYNTFHKMEELQDEVEILLDFLAEDESVHDELVAQLAE
                     LDKIMTSYEMTLLLSEPYDHNNAILEIHPGSGGTEAQDWGDMLLRMYTRYGNAKGFKV
                     EVLDYQAGDEAGIKSVTLSFEGPNAYGLLKSEMGVHRLVRISPFDSAKRRHTSFTSVE
                     VMPELDDTIEVEIREDDIKMDTFRSGGAGGQNVNKVSTGVRLTHIPTGIVVQSTVDRT
                     QYGNRDRAMKMLQAKLYQMEQEKKAAEVDSLKGEKKEITWGSQIRSYVFTPYTMVKDH
                     RTSYEVAQVDKVMDGDLDGFIDAYLKWRIS"
     gene            complement(52883..53539)
                     /locus_tag="ACL29Z_000057"
     CDS             complement(52883..53539)
                     /locus_tag="ACL29Z_000057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004256822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HGR0068449.1"
                     /translation="MAVKDFMTRKVVYISPDTTVSHAADLMREQGLHRLPVIENDQLV
                     GLVTEGTIAQASPSKATSLSIYEMNYLLNKTKVKDVMIRDVVTVSGYASLEDATYLML
                     KNKISILPVVDNHQVYGVITDRDVFQAFLEIAGYGEEGIRVRFVTEDEVGVLGKIVSL
                     IVEENLNISHTVNIPRKDGKVIIEVQIDGSIDLPALKEKFEANGIQVEEIARTSAKVL
                     "
     gene            complement(53953..54663)
                     /locus_tag="ACL29Z_000058"
     CDS             complement(53953..54663)
                     /locus_tag="ACL29Z_000058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000062217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGR0068450.1"
                     /translation="MSMLKVENLSVHYGMIQAVRDVSFEVNEGEVVSLIGANGAGKTT
                     ILRTLSGLVRPSSGKIEFLGQEIQKMPAQKIVAGGLSQVPEGRHVFPGLTVMENLEMG
                     AFLKKNREENQANLKKVFSRFPRLEERKNQDAATLSGGEQQMLAMGRALMSTPKLLLL
                     DEPSMGLAPIFIQEIFDIIQDIQKQGTTVLLIEQNANKALAISDRGYVLETGKIVLSG
                     TGKELASSEEVRKAYLGG"
     gene            complement(54663..55427)
                     /locus_tag="ACL29Z_000059"
     CDS             complement(54663..55427)
                     /locus_tag="ACL29Z_000059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002913097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGR0068451.1"
                     /translation="MALLEVKQLTKHFGGLTAVGDVTLELNEGELVGLIGPNGAGKTT
                     LFNLLTGVYEPSEGTVTLDGHLLNGKSPYKIASLGLGRTFQNIRLFKDLTVLDNVLIA
                     FGNHHKQHVFTSFLRLPAFYKSEKELKAKALELLKIFDLDGDAETLAKNLSYGQQRRL
                     EIVRALATEPKILFLDEPAAGMNPQETAELTELIRRIKDEFKITIMLIEHDMNLVMEV
                     TERIYVLEYGRLIAQGTPDEIKTNKRVIEAYLGGEA"
     gene            complement(55427..56383)
                     /locus_tag="ACL29Z_000060"
     CDS             complement(55427..56383)
                     /locus_tag="ACL29Z_000060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid ABC transporter
                     permease"
                     /protein_id="HGR0068452.1"
                     /translation="MKENLKVNILWLLLLLAGYSLISVLVSVGVLNLFYVQILQQIGI
                     NIILAVGLNLIVGFSGQFSLGHAGFMAIGAYAAAIIGSKLPTYGAFFGAMLVGALLSG
                     AVALLVGIPTLRLKGDYLAVATLGVSEIIRIFIINGGSLTNGAAGILGIPNFTTWQMV
                     YFFVVITTIATLNFLRSPIGRSTLSVREDEIAAESVGVNTTKIKIIAFVFGAITASIA
                     GSLQAGFIGSVVPKDYTFINSINVLIIVVFGGLGSITGAIVSAIVLGILNMLLQDVAS
                     VRMIIYALALVLVMIFRPGGLLGTWELSLSRFFKKSKKEEQN"
     gene            complement(56387..57256)
                     /locus_tag="ACL29Z_000061"
     CDS             complement(56387..57256)
                     /locus_tag="ACL29Z_000061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_component: GO:0043190 - ATP-binding cassette (ABC)
                     transporter complex [Evidence IEA];
                     GO_function: GO:0015658 - branched-chain amino acid
                     transmembrane transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid ABC transporter
                     permease"
                     /protein_id="HGR0068453.1"
                     /translation="MLQQLVNGLILGSVYALLALGYTMVYGIIKLINFAHGDIYMMGA
                     FIGYFLINSFQMNFFVALIVAMLATAILGVVIEFLAYRPLRHSTRIAVLITAIGVSFL
                     LEYGMVYLVGANTRAFPQAIQTVRYDLGPISLTNVQLMILAISLILMILLQVIVQKTK
                     MGKAMRAVSVDSDAAQLMGINVNRTISFTFALGSALAGAAGVLIALYYNSLEPLMGVT
                     PGLKSFVAAVLGGIGIIPGAALGGFVIGLLETFATAFGMSDFRDAIVYGILLLILIVR
                     PAGILGKNVKEKV"
     gene            complement(57524..58684)
                     /locus_tag="ACL29Z_000062"
     CDS             complement(57524..58684)
                     /locus_tag="ACL29Z_000062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002206202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HGR0068454.1"
                     /translation="MKKKFALSFVALASVALLAACGEVKSGAVNTAGNSVEEKTIKIG
                     FNFEESGSLAAYGTAEQKGAQLAVDEINAAGGIDGKQIEVVDKDNKSETAEAASVTTN
                     LVTQSKVSAVVGPATSGATAAAVANATKAGVPLISPSATQDGLTKGQDYLFIGTFQDS
                     FQGKIISNYVSEKLNAKKVVLYTDNASDYAKGIAKSFRESYKGEIVADETFVAGDTDF
                     QAALTKMKGKDFDAIVVPGYYNEAGKIVNQARGMGIDKPIVGGDGFNGEEFVQQATAE
                     KASNIYFISGFSTTVEVSAKAKAFLDAYRAKYNEEPSTFAALAYDSVHLVANAAKGAK
                     NSGEIKDNLAKTKDFEGVTGQTSFDADHNTVKTAYMMTMNNGKVEAAEVVKP"
     gene            complement(58785..59033)
                     /locus_tag="ACL29Z_000063"
     CDS             complement(58785..59033)
                     /locus_tag="ACL29Z_000063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000462128.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlbG family protein"
                     /protein_id="HGR0068455.1"
                     /translation="MFEKVNRSGLIIYLYYNRDAKKLQDYGDITYHSKKHRYLQLYVP
                     TQEVEQLVGRLSKEKFIKKVRVCHIQELETPFVGNLYR"
     gene            complement(59112..59702)
                     /gene="clpP"
                     /locus_tag="ACL29Z_000064"
     CDS             complement(59112..59702)
                     /gene="clpP"
                     /locus_tag="ACL29Z_000064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000613477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease proteolytic subunit
                     ClpP"
                     /protein_id="HGR0068456.1"
                     /translation="MIPVVIEQTSRGERSYDIYSRLLKDRIIMLTGPVEDNMANSVIA
                     QLLFLDAQDSTKDIYLYVNTPGGSVSAGLAIVDTMNFIKADVQTIVMGMAASMGTVIA
                     SSGAKGKRFMLPNAEYMIHQPMGGTGGGTQQTDMAIAAEHLLKTRNTLEKILAENSGQ
                     SMEKVHADAERDNWMSAQETLEYGFIDEIMANNSLN"
     gene            complement(59876..60505)
                     /gene="upp"
                     /locus_tag="ACL29Z_000065"
     CDS             complement(59876..60505)
                     /gene="upp"
                     /locus_tag="ACL29Z_000065"
                     /EC_number="2.4.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002883819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004845 - uracil phosphoribosyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0009116 - nucleoside metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="uracil phosphoribosyltransferase"
                     /protein_id="HGR0068457.1"
                     /translation="MGKIEVINHPLIQHKLSILRRTDTSTKAFRELVDEIAMLMGYEV
                     LRDLPLEDVEIETPITKTVQKQLAGKKLAIVPILRAGIGMVDGLLSLVPAAKVGHIGM
                     YRDEETLQPVEYLVKLPEDIDQRQIFVVDPMLATGGSAILAVDSLKKRGASNIKFVCL
                     VSAPEGVKALQEAHPDVEIFTAALDERLNEHGYIVPGLGDAGDRLFGTK"
     gene            complement(60594..61061)
                     /locus_tag="ACL29Z_000066"
     CDS             complement(60594..61061)
                     /locus_tag="ACL29Z_000066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000138511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytidine/deoxycytidylate deaminase family
                     protein"
                     /protein_id="HGR0068458.1"
                     /translation="MTEKRLAWDEYFAAQALLIANRSTCKRAKVGAILVKDNKVISTG
                     YNGSVSGTEHCIDHECLVIEGHCVRTLHAEVNAILQGAERGVPKGFTAYVTHFPCLNC
                     TKQLLQVGCKRVVYINQYRMDDYAQYLYQEKGTELTHLPLETVQTALKEADLM"
     gene            complement(61080..61637)
                     /locus_tag="ACL29Z_000067"
     CDS             complement(61080..61637)
                     /locus_tag="ACL29Z_000067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000003900.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HGR0068459.1"
                     /translation="MSERRISEKSLENLRKSNQESNLLTREAIETALLQLLEKKELTK
                     ISISELVKRAGVSRAAFYRNYDSKEEILESVFKRTVHNIMEQLHHYDLKTDLYLVWVH
                     LFREARKEARVIQLALDYHLEKIFVQAMQEFLEKYHGKSKGVSSYLHSFWSSAIVSVL
                     LKWIKDGMKVPAEKIADLGLPFFKK"
     gene            61762..62607
                     /locus_tag="ACL29Z_000068"
     CDS             61762..62607
                     /locus_tag="ACL29Z_000068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000219932.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HGR0068460.1"
                     /translation="MTWKIIADSGCDYRQLPTPAINTTFVSVPLTIQVADQVFVDDAS
                     LDIDQMMETMYATAEASKSACPSPDDYLRAFEGAENIFLVTITGTLSGSHNSAQLAKN
                     IYLEDHPDTKIHVIDSLSAGGEVDLLVEKLNDLIDQGLSFEEVVEAITAYQEKTKLLF
                     VLAKVDNLVKNGRLSKLIGTVVGLLNIRMVGKASETGTLELLQKARGSKKSVQAAYDE
                     LVKAGYAGGRIVMAQRNNEKCCQQLSERIRETFPQADIKILPTSGLCSFYAEEGGLLM
                     GYEID"
     gene            62666..63841
                     /locus_tag="ACL29Z_000069"
     CDS             62666..63841
                     /locus_tag="ACL29Z_000069"
                     /EC_number="1.14.13.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677051.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA];
                     GO_function: GO:0050661 - NADP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HGR0068461.1"
                     /translation="MKHFDTIVIGGGPAGMMATISSSFYGQKTLLIEKNRKLGKKLAG
                     TGGGRCNVTNNGSLDNLLAGIPGNGRFLYSVFSQFDNHDIINFFTENGVKLKVEDHGR
                     VFPASDKSRTIIEALEKKITELGGQVATQIEIVSVKKVDNQFVLKSADQTFTCEKLIV
                     TTGGKSYPSTGSTGFGHEIARHFKHTITDLEAAESPLLTDFPHKALQGISLDDVTLSY
                     GKHVITHDLLFTHFGLSGPAALRMSSFVKGGEVLSLDVLPQLSEKDLVTFLEKNREKS
                     LKNALKTLLPERLAEFFVQGYPEKVKQLTEKEREQLVQSIKELKIPVTGKMSLAKSFV
                     TKGGVSLKEINPKTLESKLVPGLHFAGEVMDINAHTGGFNITSALCTGWVAGSLHYD"
     gene            63861..64316
                     /locus_tag="ACL29Z_000070"
     CDS             63861..64316
                     /locus_tag="ACL29Z_000070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001081770.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="8-oxo-dGTP diphosphatase"
                     /protein_id="HGR0068462.1"
                     /translation="MNRREAVEFVNMCMIKNGDKVLVQDRVSPDWPGITFPGGHVERG
                     ESFVDAVIREVKEETGLIISKPQLCGIKNWYDDKDYRYVVLFYKTEHFTGELQSSDEG
                     KVWWEDFENLSHLKLATDDMSDMLRVFLEEDLSEFFYYKNGDDWLYDLK"
     gene            complement(64336..65090)
                     /locus_tag="ACL29Z_000071"
                     /pseudo
     CDS             complement(64336..65090)
                     /locus_tag="ACL29Z_000071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000274794.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
     gene            65173..66651
                     /locus_tag="ACL29Z_000072"
     CDS             65173..66651
                     /locus_tag="ACL29Z_000072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844893.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sodium-dependent transporter"
                     /protein_id="HGR0068463.1"
                     /translation="MVFLTDLRKHDRIVKSINQTEGYLTTQVAFSYFEKGDQSLTMSE
                     KSQWGSKLGFILASAGSAIGLGSVWKFPYMTAANGGGGFLLIFLISTILIGFPLLLAE
                     FALGRSAGVSAIKTFGKLGKNNKYNFIGWIGAFALFILLSFYSVIGGWILVYLGIEFG
                     KLFQLGGTGDYAQLFTSIISNPAIALVAQAAFILLNIFIISRGVQKGIERASKVMMPL
                     LFIIFVFIIGRSLSLPNAMEGVLYFLKPDFSKLTSAGLLYALGQSFFALSLGVTVMLT
                     YASYLDKKTNLVQSGISIVAMNISISIMAGLAIFQARSPFNIQSEGGPSLLFIVLPQL
                     FDKMPFGTIFYVLFLFATVTSSVVMLEINVGNITNQDNSKRAKWSVILGILTFVFGIP
                     SALSYGVMADVHIFGKTFFDAMDFLVSNLLMPFGALYLSLFTGYIFKKALAMEELHLD
                     ERAWKQGLFQVWLFLLRFFVPSFQSSSLWSSLPNLCNQKGLE"
     gene            complement(66672..67616)
                     /gene="manA"
                     /locus_tag="ACL29Z_000073"
     CDS             complement(66672..67616)
                     /gene="manA"
                     /locus_tag="ACL29Z_000073"
                     /EC_number="5.3.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398143.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004476 - mannose-6-phosphate isomerase
                     activity [Evidence IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="mannose-6-phosphate isomerase, class I"
                     /protein_id="HGR0068464.1"
                     /translation="MSEPLFLQSVMQEKIWGGAKLRDEFGYDIPSEKIGEYWAISAHP
                     NGVSKVANGRYEGTDLATLYAEHRELFGNRPEPVFPLLTKILDANDWLSVQVHPDDAY
                     GLEHEGELGKTECWYIIAADEGSEIIYGHNAKSKEELRQQIEDKNWDDLLTKVPVKAG
                     DFFYVPSGTMHAIGAGIFILETQQSSDTTYRVYDFDRKDDKGNLRELHLEKSIDVLNI
                     GEPANSRPVTVKADDLRSTLLVSNDFFAVYKWEITGKVDFEKTADYSLLSVLAGQGQL
                     TVDGKNYPIQKGSHFILPSDVEAWTLEGQGLELIVSHP"
     gene            complement(67748..68053)
                     /locus_tag="ACL29Z_000074"
                     /pseudo
     CDS             complement(67748..68053)
                     /locus_tag="ACL29Z_000074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002884744.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0004553 - hydrolase activity, hydrolyzing
                     O-glycosyl compounds [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="family 1 glycosylhydrolase"
     gene            68349..69350
                     /locus_tag="ACL29Z_000075"
                     /pseudo
     CDS             68349..69350
                     /locus_tag="ACL29Z_000075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611577.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS630 family transposase"
     gene            complement(69467..69814)
                     /locus_tag="ACL29Z_000076"
     CDS             complement(69467..69814)
                     /locus_tag="ACL29Z_000076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003017645.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HGR0068465.1"
                     /translation="MNLNQLDIIVSNVPQVCADLEHILDKKADYADDGFAQFTIGSHC
                     LMLSQNHLVPLENFQSGIIIHIEVEDVDQNYKRLNELGIKVLHGPTVTDWGTESLLVQ
                     GPAGLVLDFYRMK"
     gene            complement(69925..71700)
                     /gene="spxB"
                     /locus_tag="ACL29Z_000077"
     CDS             complement(69925..71700)
                     /gene="spxB"
                     /locus_tag="ACL29Z_000077"
                     /EC_number="1.2.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000191798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0047112 - pyruvate oxidase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate oxidase"
                     /protein_id="HGR0068466.1"
                     /translation="MTQGKITASAAMLNVLKTWGVDTIYGIPSGTLSSLMDALAEDKD
                     IRFLQVRHEETGALAAVMQAKFGGSIGVAVGSGGPGATHLINGVYDAAMDNTPFLAIL
                     GSRPVNELNMDAFQELNQNPMYNGIAVYNKRVAYAEQLPKVIDEACRAAVSKKGPAVV
                     EIPVNFGFQEIDENSYYGSGSYERSFIAPALNEVEIDKAVEILNNAERPVIYAGFGGV
                     KAGEVITELSRKIKAPIITTGKNFEAFEWNYEGLTGSAYRVGWKPANEVVFEADTVLF
                     LGSNFPFAEVYEAFKNTEKFIQVDIDPYKLGKRHALDASILGDAGQAAKAILDKVNPV
                     ESTPWWRANVKNNQNWRDYMNKLEGKTEGELQLYQVYNAINKHADQDAIYSIDVGNTT
                     QTSTRHLHMTPKNMWRTSPLFATMGIALPGGIAAKKDNPDRQVWNIMGDGAFNMCYPD
                     VITNVQYDLPVINLVFSNAEYGFIKNKYEDTNKHLFGVDFTNADYAKIAEAQGAVGFT
                     VDRIEDIDAVVAEAVKLNKEGKTVVIDARITQHRPLPVEVLELDPKLHSEEAIKAFKE
                     KYEAEELVPFRLFLEEEGLQSRAIK"
     gene            complement(71907..74150)
                     /locus_tag="ACL29Z_000078"
     CDS             complement(71907..74150)
                     /locus_tag="ACL29Z_000078"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000136280.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0042625 - ATPase-coupled ion transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0006812 - monoatomic cation transport
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="heavy metal translocating P-type ATPase"
                     /protein_id="HGR0068467.1"
                     /translation="MTEIVKASLENGIQKIRIRAEKGYHPTHIQLQKGIPAEITFHRA
                     TPSNCYKEILFEEEGILEPIGVDEEKVIRFTPQELGRHEFSCGMKMQKGSYTVVEKTR
                     KSLSLLQRFWIISIFTVPLVILMIGMLTGSISHQVMHWGTFLATTPIMLVAGKPYIQS
                     AWASFKKHNANMDTLVALGTLVAYFYSLVALFAGLPVYFESAGFILFFVLWGAVFEEK
                     MRKNTSQAVEKLLDLQAKTAEVLSDDSYVQVPLEQVKVGDLIRVRPGEKIAVDGVVVE
                     GVSSIDESMVTGESLPVDKTVGDTVIGSTINHSGTLVFRAEKVGSETVLAQIVDFVKK
                     AQTSRAPIQDLTDKISGIFVPVVVILGIMTFWVWFVLLRDSVVVLGASFVSSLLYGVA
                     VLIIACPCALGLATPTALMVGTGRSAKMGVLLKNGTVLQEIQKVQTLVFDKTGTLTEG
                     KPVVTDIIGDEVEVFGLAASLEDASQHPLAEAIVKRASEAGLEFQTVENFQSLHGKGV
                     SGRINGKQVLLGNAKMLDGMDISNTYQDKLEELEKEAKTVVFLAVDNEIKGLLALQDI
                     PKENAKLAISQLKKRGLRTVMLTGDNAGVARAIADQIGIEEVIAGVLPEEKAHEIHKL
                     QQSGKVAFVGDGINDAPALSVADVGIAMGAGTDIAIESADLVLTTNNLLGVVRAFDMS
                     KKTFHRILLNLFWAFIYNVVGIPIAAGVFSGVGLALNPELAGLAMAFSSVSVLTSSLL
                     LNFSKID"
     gene            complement(74160..74531)
                     /locus_tag="ACL29Z_000079"
     CDS             complement(74160..74531)
                     /locus_tag="ACL29Z_000079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000932058.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cupredoxin domain-containing protein"
                     /protein_id="HGR0068468.1"
                     /translation="MLNSIVTIICIALIAFILFWFFKKPEKSGQKAQQKNGYQEIRVE
                     VMGGYTPELIVLKKSVPARIVFDRKDPSPCLDQIVFPDFGVHANLPMGEEYVVEITPE
                     QAGEFGFACGMNMMHGKMIVE"
     gene            complement(74542..74937)
                     /locus_tag="ACL29Z_000080"
     CDS             complement(74542..74937)
                     /locus_tag="ACL29Z_000080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004256226.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA];
                     GO_process: GO:0006825 - copper ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="CopY/TcrY family copper transport repressor"
                     /protein_id="HGR0068469.1"
                     /translation="MQISDAEWQVMKIIWMQGEQTSTDLIRVLAERFDWSKSTVQTLL
                     ARLVEKECLTRKKEGKSFVYSALLTLDQSRDLLVQDIKDKVCSRRIRNLLADLIVECE
                     FTQTDLEDLEAVISEKKSSAVTEVRCNCM"
     regulatory      75121..75219
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            75303..76094
                     /gene="thiD"
                     /locus_tag="ACL29Z_000081"
     CDS             75303..76094
                     /gene="thiD"
                     /locus_tag="ACL29Z_000081"
                     /EC_number="2.7.1.49"
                     /EC_number="2.7.4.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000221716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008902 - hydroxymethylpyrimidine kinase
                     activity [Evidence IEA];
                     GO_function: GO:0008972 - phosphomethylpyrimidine kinase
                     activity [Evidence IEA];
                     GO_process: GO:0009228 - thiamine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional hydroxymethylpyrimidine
                     kinase/phosphomethylpyrimidine kinase"
                     /protein_id="HGR0068470.1"
                     /translation="MTYLPVALTIAGTDPSGGAGIMADLKSFQARDVYGMAVVTSLVA
                     QNTRGVQLIEHVSPQMLKAQLESVFSDIPPQAVKTGMLATTEIMEIIQPYLKKLDCPY
                     VLDPVMVATSGDALIDSSARDYLKTNLLPLATIITPNLPEAEEIVGFSIHDPEDMQRA
                     GRLILKEFGPQSVVIKGGHLKGGAKDFLFTKNEQFVWESPRIQTCHTHGTGCTFAAVI
                     TAELAKGKSLYQAVDKAKAFITKAIQDAPQLGHGSGPVNHTTFKD"
     gene            complement(76304..76936)
                     /gene="thiE"
                     /locus_tag="ACL29Z_000082"
     CDS             complement(76304..76936)
                     /gene="thiE"
                     /locus_tag="ACL29Z_000082"
                     /EC_number="2.5.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001078228.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004789 - thiamine-phosphate
                     diphosphorylase activity [Evidence IEA];
                     GO_process: GO:0009228 - thiamine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine phosphate synthase"
                     /protein_id="HGR0068471.1"
                     /translation="MNREALRLYLVTNRYQDSVESFLAKVETACRSGVTIVQLREKNL
                     TTNQYYQLAKQVKEITVAYQVPLIIDDRLDVCLAVDAAGLHIGDDELPVSVARKVLGP
                     EKILGVTAKTVKRALEAEKSGADYLGTGAIFPTTTKENAPITLISTLKTICQTVAIPV
                     VAIGGLTSENIDQLIGTGIAGVAVVRDLMQAEDIEAKTQAFLTKLHDILS"
     gene            complement(76929..77732)
                     /locus_tag="ACL29Z_000083"
     CDS             complement(76929..77732)
                     /locus_tag="ACL29Z_000083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001155192.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxyethylthiazole kinase"
                     /protein_id="HGR0068472.1"
                     /translation="MQEFTNPFPIGSSSLIHCMTNEISCEMLANGILALGCKPVMADD
                     PREVLDFTKQSQALFINLGHLSAEKEKAIRIAASYAAQVCLPMVVDAVGVTTSSIRKS
                     LVKDLLDYRPTVLKGNMSEIRSLVGLKHHGVGVDASAKDQETEDLLQVLKDWCQTYPG
                     MSFLVTGPKDLIVSKNQVAVLENGCTELDWITGTGDLVGALTAVFLSQGKTGFEASCL
                     AVSYLNIAAEKIVVQGMGLEEFRYQVLNQLSLLRRDENWLDTIKGEVYE"
     gene            complement(77732..78256)
                     /gene="thiW"
                     /locus_tag="ACL29Z_000084"
     CDS             complement(77732..78256)
                     /gene="thiW"
                     /locus_tag="ACL29Z_000084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001225563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005215 - transporter activity [Evidence
                     IEA];
                     GO_process: GO:0006810 - transport [Evidence IEA];
                     GO_process: GO:0009228 - thiamine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="energy coupling factor transporter S component
                     ThiW"
                     /protein_id="HGR0068473.1"
                     /translation="MRKHQLQVHKLTILSMMIALDVVLTPIFRIEGMAPMSSVVNILA
                     GIMMGPVYALAMATVTAIIRMTTQGIPPLALTGATFGALLAGLFYKYGRKFYFSALGE
                     IVGTGIIGSIVSYPVMVLFTGSAAKLSWFIYTPRFFGATLIGTAISFIAFRFLIKQEF
                     FKKVQGYFFSERID"
     gene            complement(78261..78953)
                     /gene="tenA"
                     /locus_tag="ACL29Z_000085"
     CDS             complement(78261..78953)
                     /gene="tenA"
                     /locus_tag="ACL29Z_000085"
                     /EC_number="3.5.99.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864194.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0050334 - thiaminase activity [Evidence
                     IEA];
                     GO_process: GO:0006772 - thiamine metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="thiaminase II"
                     /protein_id="HGR0068474.1"
                     /translation="MEFTDIAMELSKKAWQVSFHHPFILQLQEGNLEPAIFRYYLIQD
                     AYYLKAFSEIYHLLADKTSNQEMKRLLKQNAQGLVEGELFIRQQFFKELEINDQEMEQ
                     HPIAPTCYHYISHIYRQFAEPNLAIAFASLLPCPWLYHDIGKSLNLKPSPNPLYQQWI
                     ETYITDELEQQIREEGALVNQLYRESDETDKQKMLDAFHISVHMEAKFWEMAYQHQTW
                     KSDLQSLEKGEE"
     gene            complement(78964..79614)
                     /locus_tag="ACL29Z_000086"
     CDS             complement(78964..79614)
                     /locus_tag="ACL29Z_000086"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000241367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter transmembrane
                     component T"
                     /protein_id="HGR0068475.1"
                     /translation="MVKVATQTPIISLFLLILSLETSFIPSIALNLSVVAFCVLFMLY
                     YRRFKMLAWMIILAILPSFANYWAVQLHGDASQAVMLGTRAFVTVCIGLVFVSSISLK
                     ELLLYLAQKGLSRSWSYALIVVFNSFPLIQQEIKSLKEACLLRGQELHFWSPLIYSKV
                     LMTVFRWRHLYLRALSAHGYDEHAQLKNSYRTFYIPKKTKLIYLLFFLLLQTSLFL"
     gene            complement(79616..81001)
                     /locus_tag="ACL29Z_000087"
     CDS             complement(79616..81001)
                     /locus_tag="ACL29Z_000087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000522086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HGR0068476.1"
                     /translation="MGLELRAIQSPIFPEPFDFTFHAQAFTLLVGSSGSGKSSLFQVI
                     AQVSSPPYSGQVLIDGSEVSQLSIIARVQKVGILFQNPNHQFTMENLFEELIFTLENI
                     GYHLQEIDSKIAEVVQQCRCEAILHRPIHHLSGGEKQKAALAVLFAMNPRVYLLDEPF
                     ASIDRKSRIEILEILKELALDGKTVILCDHDLSDYKAYIDHMVELRDGKLREVFQIPS
                     YEMTEVASKEVASSPELFHMDRTTCEFGNRSLFSIADFTFYQGISCILGDNGVGKSTF
                     FRSILQFQKYKGSITWKGSVLKKKKSLYRDLTGVVQEAEKQFIRVSLREELQLDGPDS
                     ERNQRIFQALRDFDLEQAVDKSPYQLSGGQQKILQLLTILTSKASVILLDEPFAGLDD
                     RACHYFCKWIVEERNQGRSFLLISHRLDPLISVVDYWIEMTSQGLRHVKEVTITKPLT
                     SQSSNTQGEVR"
     gene            complement(81002..81562)
                     /locus_tag="ACL29Z_000088"
     CDS             complement(81002..81562)
                     /locus_tag="ACL29Z_000088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000915269.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HGR0068477.1"
                     /translation="MLKKWQLKDVILLAFLSIFFGGVFVGSGYVYNILSLLLTPLGLQ
                     AFANEILFGLWCMAAPIAAIFVPRVGSATIGEVLAALAEVLYGSQFGLGALLSGLVQG
                     LGSEFGFIVTKNRYESWLSLTANSIGITLVSFVYEYIKLGYYAFSLPFVLSLLVVRFI
                     SVYFFCTILVRAIVKLYHQFATGGKA"
     regulatory      complement(81824..81912)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            complement(82121..82750)
                     /gene="thiE"
                     /locus_tag="ACL29Z_000089"
     CDS             complement(82121..82750)
                     /gene="thiE"
                     /locus_tag="ACL29Z_000089"
                     /EC_number="2.5.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000468574.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004789 - thiamine-phosphate
                     diphosphorylase activity [Evidence IEA];
                     GO_process: GO:0009228 - thiamine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine phosphate synthase"
                     /protein_id="HGR0068478.1"
                     /translation="MFHKELLKLYFICGTTTCQGKNLYTVVEEALKGGITLFQFREKG
                     EGALEGLEKLELAIQIKELCKKYNVPFIVNDDIDLAMEIDADGVHVGQDDIGVDEIRK
                     LMPDKIIGLSIRNEEEFQQSKVEYVDYVGVGPVFDTQSKDDAGGAIGYEGLELMRKLL
                     PQMPLVAIGGIQTKHIKDIIKTNMDGVSIISAISYAKNIEKTVREMSEQ"
     gene            complement(82752..83534)
                     /gene="thiM"
                     /locus_tag="ACL29Z_000090"
     CDS             complement(82752..83534)
                     /gene="thiM"
                     /locus_tag="ACL29Z_000090"
                     /EC_number="2.7.1.50"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000202454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004417 - hydroxyethylthiazole kinase
                     activity [Evidence IEA];
                     GO_process: GO:0009228 - thiamine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxyethylthiazole kinase"
                     /protein_id="HGR0068479.1"
                     /translation="MTSLKLLKEKAPLVICITNDVVKNFTANGLVALGASPAMSEFPE
                     DLEDLLKYAGGLLINIGTLTDENWKLYQAALKIAEKYNVPAVLDPVACGAGEYRKKVA
                     DDLINNYKLAAIRGNAGEIASLVGIDVASKGVDSAGVDNIDEIALAANEKFNIPIVVT
                     GEVDAIAVNGEVVTIHNGSAMMPKVIGTGCLLGAVVASFIGLEKGQELKSLETAMLVY
                     NIAGEMAEKRPNGHLPGTFKVEFINALYEITDEDVKEFKRVK"
     gene            complement(83771..84439)
                     /locus_tag="ACL29Z_000091"
     CDS             complement(83771..84439)
                     /locus_tag="ACL29Z_000091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000449895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TenA family protein"
                     /protein_id="HGR0068480.1"
                     /translation="METQDYAFQPGLTVGELLKSSQKDWKAAINHRFVKELFAGTIEN
                     KVLKDYLIQDYHFFDAFLSMLGACVAHADKLESKLRFAKQLGFLEADEDGYFQKAFKE
                     LKVAENDYLEVTLHPVTKAFQDLMYSAVASSDYAHLLIMLVIAEGLYLDWGSKDLALP
                     EVYIHSEWINLHRGPFFAEWVQFLVDELNRVGKNREDLTELQQRWNQAVALELAFFDI
                     GYDV"
     regulatory      complement(84654..84742)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            complement(84996..86132)
                     /gene="lctO"
                     /locus_tag="ACL29Z_000092"
     CDS             complement(84996..86132)
                     /gene="lctO"
                     /locus_tag="ACL29Z_000092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000120720.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-lactate oxidase"
                     /protein_id="HGR0068481.1"
                     /translation="MSYKTSNAEGHVDFINTYDLEPMAQQVIPKAAFGYIASGAEDTF
                     TLRENIRAFNHKLIVPHTLCDVENPSTEIEFAGEKLSSPIIMAPVAAHKLANEQGEVA
                     TARGVHEFGSLYTTSSYSTVDLPEISEALQGTPHWFQFYFSKDDGINRHIMDRVKAEG
                     YKAIVLTADATVGGNREVDKRNGFVFPVGMPIVEEYLPEGAGKSMDFVYKSAKQRLSP
                     RDVEFIAEYSGLPVYVKGPQCREDVERSLAAGASGIWVTNHGGRQIDGGPAAFDSLQE
                     VAEAVDKRVPIVFDSGVRRGQHVFKALASGADLVAIGRPVIYGLALGGSVGVRQVFEH
                     LNAELKTVMQLSGTQTIEDVKHFKLRHNPYNPTFPVDPRDLKLY"
     gene            complement(86758..88248)
                     /gene="lysS"
                     /locus_tag="ACL29Z_000093"
     CDS             complement(86758..88248)
                     /gene="lysS"
                     /locus_tag="ACL29Z_000093"
                     /EC_number="6.1.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003055423.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004824 - lysine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006430 - lysyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="lysine--tRNA ligase"
                     /protein_id="HGR0068482.1"
                     /translation="MSTEHMEELNDQQIVRREKMAALREQGIDPFGKRFERTANSQEL
                     KDKYTNLDKEQLHDKNETATIAGRLVTKRGKGKVGFAHLQDREGQIQIYVRKDAVGEE
                     NYEIFKKADLGDFLGVEGEVMRTDMGELSIKATHITHLSKALRPLPEKFHGLTDVETI
                     YRKRYLDLISNRESFERFVTRSKIISEIRRYLDQKGFLEVETPVLHNEAGGAAARPFI
                     THHNAQNIDMVLRIATELHLKRLIVGGMERVYEIGRIFRNEGMDATHNPEFTSIEVYQ
                     AYADFQDIMDLTEGIIQHAAKSVKGDGPVNYQGTEIKINEPFKRVHMVDAIREITGVD
                     FWQDMTLEEAKAIAAEKKVPVEKHYTEVGHIINAFFEEFVEETLIQPTFVYGHPVAVS
                     PLAKKNPEDQRFTDRFELFIMTKEYGNAFTELNDPIDQLSRFEAQAKAKELGDDEATG
                     IDYDYIEALEYGMPPTGGLGIGIDRLCMLLTDTTTIRDVLLFPTMK"
     gene            complement(88388..88522)
                     /locus_tag="ACL29Z_000094"
                     /pseudo
     CDS             complement(88388..88522)
                     /locus_tag="ACL29Z_000094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000120720.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="lactate oxidase"
     gene            88748..89416
                     /locus_tag="ACL29Z_000095"
     CDS             88748..89416
                     /locus_tag="ACL29Z_000095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000384089.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0006865 - amino acid transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HGR0068483.1"
                     /translation="MVEQYLPLYQKAFFLTLHIAVWGILGSFLLGLIVSIIRHYRILV
                     LSQVATAYIELSRNTPLLIQLFFLYFGLPRIGIVLSSEVCATLGLVFLGDSYMAESFR
                     SGLEAISQTQQEIGLAIGLTPLQVFYYVVLPQATAVALPSFSANVIFLIKETSVFSAV
                     ALADLMYVAKDLIGLYYETDIALAMLVVAYLIMLLPISLVFSWIERRLRHAGFGNPST
                     LSRK"
     gene            89376..90053
                     /locus_tag="ACL29Z_000096"
     CDS             89376..90053
                     /locus_tag="ACL29Z_000096"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001154125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0006865 - amino acid transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HGR0068484.1"
                     /translation="MQDSGIQVLFQGNNLLRILQGLGVTIGISILSVLLSMMFGTVMG
                     IIMTSHSRIIRFLTRLYLEFIRIMPQLVLLFIVYFGLARNFNINISGETSAIIVFTLW
                     GTAEMGDLVRGAITSLPKHQFESGQALGLTNVQLYYHIIIPQVLRRLLPQAINLVTRM
                     IKTTSLVVLIGVVEVTKVGQQIIDSNRLTIPTASFWIYGTILVLYFAVCYPISKLSTH
                     LEKHWRN"
     gene            90054..90812
                     /locus_tag="ACL29Z_000097"
     CDS             90054..90812
                     /locus_tag="ACL29Z_000097"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012000401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HGR0068485.1"
                     /translation="MSETILEIKELKKSFGDNPILQGLSLEIKKGEVVVILGPSGCGK
                     STLLRCLNGLESIQGGDIFLDGQSIVENKKNFHLVRQKIGMVFQSYELFPHLDVLQNL
                     ILGPIKTQGRDKKEVTEEALQLLDRVGLLDKQHSFARQLSGGQKQRVAIVRALLMHPE
                     IILFDEVTASLDPEMVREVLELINDLAQEGRTMILVTHEMQFAQAIADRIIFLDQGKI
                     AEEGTAQAFFTNPQTKRAQEFLNVFDFSQFGSYL"
     gene            90824..91685
                     /locus_tag="ACL29Z_000098"
                     /pseudo
     CDS             90824..91685
                     /locus_tag="ACL29Z_000098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000765255.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine ABC transporter substrate-binding
                     protein"
     gene            complement(91765..92412)
                     /locus_tag="ACL29Z_000099"
     CDS             complement(91765..92412)
                     /locus_tag="ACL29Z_000099"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001002414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGR0068486.1"
                     /translation="MNEIIILKNIELKLKKTCVFQNLNFSCKQGEIIGITGANGSGKS
                     VLFKLIAGLYSPSYGEVLINGENIVPERKIPANLGALIEEPGFINYYSGFKNLQYLAS
                     IRGVVGNQEINDTLKIVGLYEQKDQKVKTYSLGMRKKLGIAQAIMENPSILLLDEPMN
                     ALDKSSVENMRTLFRKLSSEKGTTILIASHSEEDIRILCDKVYAIEDKVCTLCSD"
     gene            complement(92409..93107)
                     /locus_tag="ACL29Z_000100"
     CDS             complement(92409..93107)
                     /locus_tag="ACL29Z_000100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000517353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0068487.1"
                     /translation="MGKLSSHMWRLNQIIYTKYFWGYVLFWILICLGLWYWLEGNDRL
                     VIEILKGPNLSQNSFLVLSIWLLHWFIIHTFFLAVVYRRRASDFFMEVIRFSSIKLWI
                     RYQIWTCFLYGLILIMVKVLVIQFMLQLPNWDIGVLFIVDSLNACVLVLFCFMLYALG
                     ANVQMNFACVSFFLLMIVFGGLFVGNRTNYLFYILNRGNGDIGRDLFLQLLFLVFLFK
                     SIFYFTRQKRRFIE"
     gene            complement(93117..93869)
                     /locus_tag="ACL29Z_000101"
     CDS             complement(93117..93869)
                     /locus_tag="ACL29Z_000101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0068488.1"
                     /translation="MKQFVQFYKKDFLSVLVYFILLLSCVLSSTVYLLRCRQYSIHPN
                     VLEWILVLLQDMTTGVYCFPFTYILFFFYLMNNYFNRLECRIRLKSIKHFTSFSFKLA
                     ALSTGIWTATLFLLIFLIAFSNGFSFSLEIKEVDFLREFYGISIANNASFFIGFFFSY
                     IAYYFFLSLLTISSFSWFKKSNMSLVFLFTFLFVESLFWIYQLDNGIIGLLPIFQYMV
                     NSNPYALIYWLTLLSIIIPLTVFSVHRNWRRV"
     gene            complement(93869..94633)
                     /locus_tag="ACL29Z_000102"
     CDS             complement(93869..94633)
                     /locus_tag="ACL29Z_000102"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000394067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0068489.1"
                     /translation="MEFFICNLVRVVQSPRFYMSLFLTLLCMSLGNFLAFNGIYKIEG
                     LSIFFAASSIRGFSPISLVAALICTLPYSSQIIEDAESHFLTAQLCRISKKKYLAIVG
                     STVIISSFLVFFLPYLLLLGINLLVTPYQEIYIGDYSGALKELFDSNQFLYSLVTTLW
                     YGVWGAVFSIFGLASALLVKKKIGAIFIPVAYMMVGGIFWAILGLSYLEPVTTLALGY
                     QKDISLSLVSGHLAFILFVSCLVVYGTFFLHSEDYV"
     gene            complement(94729..95028)
                     /locus_tag="ACL29Z_000103"
     CDS             complement(94729..95028)
                     /locus_tag="ACL29Z_000103"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0068490.1"
                     /translation="MPRWGSDTTSELEKENASAGINNNDSTGGGKRLNTSIRSAYSGS
                     DITPVYSLGSGSRIVMYYNGGGDNYIGSGTRLAMAPQFGNHVRIHTSGSWNPDSY"
     gene            complement(95312..95944)
                     /gene="pyrE"
                     /locus_tag="ACL29Z_000104"
     CDS             complement(95312..95944)
                     /gene="pyrE"
                     /locus_tag="ACL29Z_000104"
                     /EC_number="2.4.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000170913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004588 - orotate
                     phosphoribosyltransferase activity [Evidence IEA];
                     GO_process: GO:0009220 - pyrimidine ribonucleotide
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="orotate phosphoribosyltransferase"
                     /protein_id="HGR0068491.1"
                     /translation="MTLAKDIASHLLKIQAVYLKPEEPFTWASGIKSPIYTDNRVTLA
                     YPETRTLIENGFVEAIKEAFPEVEVIAGTATAGIPHGAIIADKMDLPFAYIRSKPKDH
                     GAGNQIEGRVAQGQKMVVVEDLISTGGSVLEAVAAAKREGADVLGVVAIFSYQLPKAD
                     KNFADAGVKLVTLSNYSELIHLAQEEGYITPEGLDLLKRFKEDQENWQEG"
     gene            complement(95978..96679)
                     /gene="pyrF"
                     /locus_tag="ACL29Z_000105"
     CDS             complement(95978..96679)
                     /gene="pyrF"
                     /locus_tag="ACL29Z_000105"
                     /EC_number="4.1.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001206708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004590 - orotidine-5'-phosphate
                     decarboxylase activity [Evidence IEA];
                     GO_process: GO:0006207 - 'de novo' pyrimidine nucleobase
                     biosynthetic process [Evidence IEA];
                     GO_process: GO:0044205 - 'de novo' UMP biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="orotidine-5'-phosphate decarboxylase"
                     /protein_id="HGR0068492.1"
                     /translation="MREHRPVIALDFPSFEAVKEFLALFPAEESLYLKVGMELYYAAG
                     PEIVSYLKGLGHSVFLDLKLHDIPNTVKSAMKVLSQLGVDMTNVHAAGGVEMMKAARE
                     GLGSQAKLIAVTQLTSTSEAQMQEFQNIQTSLQESVIHYAKKTAEAGLDGVVCSAQEV
                     QVIKQATNPDFICLTPGIRPAGAAVGDQKRVMTPADAYQIGSDYIVVGRPITQAEDPV
                     AAYHTIKDEWTQDWN"
     gene            complement(96912..98111)
                     /gene="divIB"
                     /locus_tag="ACL29Z_000106"
     CDS             complement(96912..98111)
                     /gene="divIB"
                     /locus_tag="ACL29Z_000106"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000031166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein DivIB"
                     /protein_id="HGR0068493.1"
                     /translation="MSKDKKNEDKEILEELKELSEWQKRNQEYLKKKAEEEAALAEEK
                     EKERQARMGEESEKSEDKQDQESETDQEDSESAKEESEEKVASSEDDKEKEEKEEPES
                     KEKEEQDKKLAKKATKEKPAKAKIPGIHILRAFTILFPSLLLLIVSAYLLSPYATMKD
                     IRVEGTVQTTADDIRQASGIQDSDYTINLLLDKAKYEKQIKSNYWVESAQLVYQFPTK
                     FTIKVKEYDIVAYYISGENHYPILSSGQLETSSVSLNSLPETYLSVLFNDSEQIKVFV
                     SELAQISPELKAAIQKVELAPSKVTSDLIRLTMNDLDEVLVPLSEMSKKLPYYSKIKP
                     QLSEPSVIDMEAGIYSYTVADKLIMEAEEKAKQEAKEAEKKQEEEQKKQEEESNRNQT
                     TQRSSRR"
     gene            complement(98121..99179)
                     /locus_tag="ACL29Z_000107"
     CDS             complement(98121..99179)
                     /locus_tag="ACL29Z_000107"
                     /EC_number="2.4.1.227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000724845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0050511 -
                     undecaprenyldiphospho-muramoylpentapeptide
                     beta-N-acetylglucosaminyltransferase activity [Evidence
                     IEA];
                     GO_function: GO:0051991 -
                     UDP-N-acetyl-D-glucosamine:N-acetylmuramoyl-L-alanyl-D-
                     glutamyl-meso-2,
                     6-diaminopimelyl-D-alanyl-D-alanine-diphosphoundecaprenol
                     4-beta-N-acetylglucosaminlytransferase activity [Evidence
                     IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA];
                     GO_process: GO:0007049 - cell cycle [Evidence IEA];
                     GO_process: GO:0008360 - regulation of cell shape
                     [Evidence IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA];
                     GO_process: GO:0030259 - lipid glycosylation [Evidence
                     IEA];
                     GO_process: GO:0051301 - cell division [Evidence IEA];
                     GO_process: GO:0071555 - cell wall organization [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine--N-acetylmuramyl-
                     (pentapeptide) pyrophosphoryl-undecaprenol
                     N-acetylglucosamine transferase"
                     /protein_id="HGR0068494.1"
                     /translation="MKKIVFTGGGTVGHVTLNLLLMPKFIEDGWEVHYIGDKRGIEHQ
                     EILKSGLDVTFHSIATGKLRRYFSWQNMLDVFKVGWGIVQSLFIMLRLRPQTLFSKGG
                     FVSVPPVIAARVSGVPVFIHESDLSMGLANKIAYKFATKMYSTFEQASSLSKVEHVGA
                     VTKVSDQKNPEPDELVDIQTHFNHKLPTVLFVGGSAGARVFNQLVTDHKKELTERYNI
                     INLTGDSSLNELSQNLFRVDYVTDLYQPLLELADIVVTRGGANTIFELLAIAKLHVIV
                     PLGREASRGDQIENAAYFVKKGYAEDLQESDLTLDSLEEKLSHLLSHKEDYQAKMKAS
                     KELKSLADFYQLLKKDLS"
     gene            complement(99183..100535)
                     /gene="murD"
                     /locus_tag="ACL29Z_000108"
     CDS             complement(99183..100535)
                     /gene="murD"
                     /locus_tag="ACL29Z_000108"
                     /EC_number="6.3.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000862950.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008764 -
                     UDP-N-acetylmuramoylalanine-D-glutamate ligase activity
                     [Evidence IEA];
                     GO_process: GO:0008360 - regulation of cell shape
                     [Evidence IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA];
                     GO_process: GO:0051301 - cell division [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-L-alanine--D-glutamate
                     ligase"
                     /protein_id="HGR0068495.1"
                     /translation="MKVIDQFKNKKVLVLGLAKSGESAARLLDKLGAIVTVNDGKPFE
                     DNPAAQCLLEEGIKVITGGHPLELLDEEFALMVKNPGIPYSNPMIEKALAKGIPVLTE
                     VELAYLISEAPIIGITGSNGKTTTTTMIGEVLTAAGQHGLLSGNIGYPASQVAQIASD
                     KDTLVMELSSFQLMGVQEFHPEIAVITNLMPTHIDYHGLFEEYVAAKWNIQNKMTAAD
                     FLVLNFNQDLVKDLASKTEATVVPFSTLEKVDGAYLEDGQLYFRGEVVMAANEIGVPG
                     SHNVENALATIAVAKLRDVDNQTIKETLSAFGGVKHRLQFVDDIKGVKFYNDSKSTNI
                     LATQKALSGFDNSKVVLIAGGLDRGNEFDELVPDITGLKKMVILGQSAERVKRAADKA
                     GVAYVEATDIADATRKAYELATQGDVVLLSPANASWDMYANFEVRGDLFIDTVAELKE
                     "
     gene            complement(100639..101280)
                     /locus_tag="ACL29Z_000109"
     CDS             complement(100639..101280)
                     /locus_tag="ACL29Z_000109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000571297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGR0068496.1"
                     /translation="MIELKNISKKFGSRQLFSDTNLHFEGGKIYALIGTSGCGKTTLL
                     NMIGRLEPYDKGQIIYDGTSLKDIKPSVFFRDYLGYLFQDFGLIESQTVKENLNLGLV
                     GKKLKEKEKISLMKQALNCVNLSYLDLKQPIFELSGGEAQRVALAKIILKDPPLILAD
                     EPTASLDPKNSEELLSILESLKNPNRTIIIATHNPLIWEQVDQVIRVTDLSHR"
     gene            complement(101282..103303)
                     /locus_tag="ACL29Z_000110"
                     /pseudo
     CDS             complement(101282..103303)
                     /locus_tag="ACL29Z_000110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000732428.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-associated integral membrane family
                     protein"
     gene            complement(103386..103685)
                     /locus_tag="ACL29Z_000111"
                     /pseudo
     CDS             complement(103386..103685)
                     /locus_tag="ACL29Z_000111"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397967.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="lactococcin 972 family bacteriocin"
     gene            complement(104050..104304)
                     /locus_tag="ACL29Z_000112"
     CDS             complement(104050..104304)
                     /locus_tag="ACL29Z_000112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000262800.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3165 family protein"
                     /protein_id="HGR0068497.1"
                     /translation="MVYLVLGILLLLLYVFATPESIKGTVNIVAMVCILVALLILLVL
                     SFLKIFQLPTEIFLAIAMLLLAYFSVRDITLMPVKKSKRR"
     gene            complement(104324..106165)
                     /gene="typA"
                     /locus_tag="ACL29Z_000113"
     CDS             complement(104324..106165)
                     /gene="typA"
                     /locus_tag="ACL29Z_000113"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003078415.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA];
                     GO_process: GO:0006950 - response to stress [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="translational GTPase TypA"
                     /protein_id="HGR0068498.1"
                     /translation="MTKLREDIRNIAIIAHVDHGKTTLVDELLKQSETLDARTELAER
                     AMDSNDIEKERGITILAKNTAVAYNGTRINIMDTPGHADFGGEVERIMKMVDGVVLVV
                     DAYEGTMPQTRFVLKKALEQDLVPIVVVNKIDKPSARPAEVVDEVLELFIELGADDDQ
                     LDFPVVYASAINGTSSLSDDPADQEATMAPIFDTIIDHIPAPVDNSDEPLQFQVSLLD
                     YNDFVGRIGIGRVFRGTVKVGDQVTLSKLDGTTKNFRVTKLFGFFGLERREIQEAKAG
                     DLIAVSGMEDIFVGETITPTDAVEALPILHIDEPTLQMTFLVNNSPFAGKEGKWVTSR
                     KVEERLQAELQTDVSLRVDPTDSPDKWTVSGRGELHLSILIETMRREGYELQVSRPEV
                     IVKEIDGVKCEPFERVQIDTPEEYQGSVIQSLSERKGEMLDMISTGNGQTRLVFLVPA
                     RGLIGYSTEFLSMTRGYGIMNHTFDQYLPLIPGEIGGRHRGALVSIDAGKATTYSIMS
                     IEERGTIFVNPGTEVYEGMIIGENSRENDLTVNITKAKQMTNVRSATKDQTAVIKTPR
                     ILTLEESLEFLNDDEYMEVTPESIRLRKQILNKAEREKANKKKKSAE"
     gene            106327..107052
                     /locus_tag="ACL29Z_000114"
     CDS             106327..107052
                     /locus_tag="ACL29Z_000114"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001235004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA pseudouridine(516) synthase"
                     /protein_id="HGR0068499.1"
                     /translation="MRLDNLLAQEKISRKAMKQALLRGKILVNGCPARSLAQNIDTGL
                     QELLFQDRIIQGYEHTYLMLHKPAGVVTANKDKELPTVMDLLPSDIQSDKLYAVGRLD
                     RDTTGLLLLTDNGPLGFQLLHPQYHVDKTYQVEVNGLLTPDHIQAFQKGIVFLDGTVC
                     KPAKLEILSASPSISQASITISEGKFHQIKKMFLSVGVKVTILKRIQFGDFTLNPDLA
                     ESNYRPLNQKELQIIKNYLEMSR"
     gene            complement(107092..107319)
                     /locus_tag="ACL29Z_000115"
                     /pseudo
     CDS             complement(107092..107319)
                     /locus_tag="ACL29Z_000115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000660075.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(107408..107788)
                     /locus_tag="ACL29Z_000116"
     CDS             complement(107408..107788)
                     /locus_tag="ACL29Z_000116"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HGR0068500.1"
                     /translation="MVTWILWALILAMLAWMGFNYLRIRRAAKIVDNEEFEALIRTGQ
                     LIDLRDPAEFHRKHILGARNIPSSQLKTSLAALRKDKPVLLYENQRAQRVTNAALYLK
                     KQGFSEIYILSYGLDSWKGKVKTS"
     gene            complement(107788..108057)
                     /locus_tag="ACL29Z_000117"
     CDS             complement(107788..108057)
                     /locus_tag="ACL29Z_000117"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000051789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YqgQ family protein"
                     /protein_id="HGR0068501.1"
                     /translation="MSLFLKKTQNFARMSLMKTFYDVQQFLKRFGIIVYMGKRLYDIE
                     LMKLELSRIYDAGLMDKLDYLEAEAVLRREHKVELDYIEKNGEKN"
     gene            108121..109029
                     /locus_tag="ACL29Z_000118"
     CDS             108121..109029
                     /locus_tag="ACL29Z_000118"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HGR0068502.1"
                     /translation="MRIQQLHYIIKIVETGSMNEAAKQLFITQPSLSNAVRDLENEMG
                     IEIFIRNPKGITLTRDGMEFLSYARQVVEQTQLLEERYKNPVAHRELFSVSSQHYAFV
                     VNAFVSLLKKSDMEKYELFLRETRTWEIIDDVKNFRSEVGVLFLNSYNRDVLTKMLDD
                     NHLLAHHLFTAQPHIFVSKTNPLAKKDKVKLSDLENFPYLSYDQGTHNSFYFSEEILS
                     QEHHKKSIVVSDRATLFNLLIGLDGYTIATGILNSNLNGDNIVSIPLDIDDPIELVYI
                     QHEKTSLSKMGERFIDYLLEEVQFDS"
     gene            complement(109083..109838)
                     /locus_tag="ACL29Z_000119"
     CDS             complement(109083..109838)
                     /locus_tag="ACL29Z_000119"
                     /EC_number="1.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001142149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family NAD(P)-dependent oxidoreductase"
                     /protein_id="HGR0068503.1"
                     /translation="MPTILITGASGGLAQEMVKLLPNDQLILLGRNKEKLAQLYGNYS
                     HAELIEIDITDDSALEALVTDLYLRYGKIDVLINNAGYGIFEGFDQIADKDIHQMFEV
                     NTFALMNLSRHLAARMKESSKGHIINIVSMAGLIATGKSSLYSATKFAAIGFSNALRL
                     ELMPYGVYVTTVNPGPIRTGFFDQADPDGTYLKSVDRFLLEPDAVAKKIVKIIGKNKR
                     ELNLPILLNLAHKFYTLFPKLADKLAGETFNYK"
     gene            complement(109859..110788)
                     /gene="rnz"
                     /locus_tag="ACL29Z_000120"
     CDS             complement(109859..110788)
                     /gene="rnz"
                     /locus_tag="ACL29Z_000120"
                     /EC_number="3.1.26.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000354350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016891 - RNA endonuclease activity,
                     producing 5'-phosphomonoesters [Evidence IEA];
                     GO_process: GO:0042780 - tRNA 3'-end processing [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease Z"
                     /protein_id="HGR0068504.1"
                     /translation="MDIQFLGTGAGQPSKARNVSSLALKLLDEINEVWLFDCGEGTQN
                     RILETTIRPRKVSKIFITHLHGDHIFGLPGFLSSRAFQANEEQTDLEIYGPQGIKSFV
                     LTSLRVSGSRLPYRIHFHEFDQDSLGKILETDKFTVYAEELDHTIFCVGYRVMQKDLE
                     GTLDAEKLKAAGVPFGPLFGKIKNGQDLVLEDGTEIKAADYISAPRPGKIITILGDTR
                     KTGASVRLAVNADVLVHESTYGKGDEKIARNHGHSTNMQAAQVAVEAGAKRLLLNHIS
                     ARFLSKDISKLKKDAATIFENVHVVKDLEEVEI"
     gene            complement(110803..111426)
                     /locus_tag="ACL29Z_000121"
     CDS             complement(110803..111426)
                     /locus_tag="ACL29Z_000121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cystathionine beta-lyase"
                     /protein_id="HGR0068505.1"
                     /translation="MTDIKTLALKYGGYTSLDKVYLDQLLAGKTDQEQLTLITPPPSV
                     VNAYFAELYQKKSPQAATDYFAELSQELNLYNTEPSFTLENKPFIRLNLSGKSFGFCY
                     ESDGLGRIFFENEEKISDDLLFEIAQIFPHQLVFEESGKIYMKPVEDEEVISLESLTA
                     LTDLERLADGRKRLKGYSQEDLLQEAAAFSGKRYFRSENRTAMLYID"
     gene            complement(111419..112657)
                     /gene="hflX"
                     /locus_tag="ACL29Z_000122"
     CDS             complement(111419..112657)
                     /gene="hflX"
                     /locus_tag="ACL29Z_000122"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000573186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005525 - GTP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase HflX"
                     /protein_id="HGR0068506.1"
                     /translation="MIETEKKEERVLLIGVELQGMDSFDLSMEELASLAKTAGAVVVD
                     SYRQKREKYDSKTFVGSGKLEEIALMVDAEEITTVIVNNRLTPRQNVNLEEVLGVKVI
                     DRMQLILDIFAMRARSHEGKLQVHLAQLKYLLPRLVGQGIMLSRQAGGIGSRGPGESQ
                     LELNRRSVRNQITDIERQLKVVEKNRATVREKRLESSTFKIGLIGYTNAGKSTIMNIL
                     TSKTQYEADELFATLDATTKSIHLGGNLQVTLTDTVGFIQDLPTELVSSFKSTLEESK
                     HVDLLVHVIDASNPYHEEHEKTVLSIMKDLDMEDIPHLTLYNKADLVEDFTPTQTPYT
                     LISAKSEDSRENLQALLLDKIKEIFEAFTLRVPFSKSYKIHDLESVAILEERDYQEDG
                     EVITGYISEKNKWRLEEFYD"
     gene            complement(112650..113534)
                     /gene="miaA"
                     /locus_tag="ACL29Z_000123"
     CDS             complement(112650..113534)
                     /gene="miaA"
                     /locus_tag="ACL29Z_000123"
                     /EC_number="2.5.1.75"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000850191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0052381 - tRNA dimethylallyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0006400 - tRNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (adenosine(37)-N6)-dimethylallyltransferase
                     MiaA"
                     /protein_id="HGR0068507.1"
                     /translation="MKTKIIVIVGPTAVGKTALAIEVAKRFNGEVVSGDSQQVYRGLD
                     IGTAKASPEEQAAVPHHLIDVREITESYSAFDFVSEAKMTIEDIQSRGKLAIIAGGTG
                     LYIQSLLEGYHLGGETPHEEILAYRASLEPYSDEELAHLVEQAGLEIPQFNRRRAMRA
                     LEIAHFGQDLENQEILYEPLIICLDDERSQLYERINHRVDLMFEAGLLDEAKWLFDHS
                     PNVQAAKGIGYKELFPYFRGEQTFEEACESLKQATRRFAKRQLTWFRNRMQVTFYQIG
                     ESGVQDRILSQIEEFLDD"
     gene            113655..113825
                     /locus_tag="ACL29Z_000124"
     CDS             113655..113825
                     /locus_tag="ACL29Z_000124"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002263068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3042 family protein"
                     /protein_id="HGR0068508.1"
                     /translation="MAKGFAKGLVTGVAGTVAAVAGAVYAFKKKVIEPEEQKAAFIEE
                     NRKKAARRRVSR"
     gene            complement(113873..114712)
                     /locus_tag="ACL29Z_000125"
     CDS             complement(113873..114712)
                     /locus_tag="ACL29Z_000125"
                     /EC_number="2.1.1.45"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003011065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thymidylate synthase"
                     /protein_id="HGR0068509.1"
                     /translation="MTKADTIFKENIECILKEGVFSEQARPKYKDGTVANSKYVTGAF
                     SEYDLSKGEFPITTLRPIAIKSAIKEVLWIYQDQSNSLEVLNDKYNVHYWNDWEVGDT
                     GTIGERYGAVVKKHDIINKLLKQLETNPWNRRNIISLWDYQAFEETDGLLPCAFQTMF
                     DVRRVDGEIYLDATLTQRSNDMLVAHHINAMQYVALQMMIAKHFGWKVGKFFYFINNL
                     HIYDNQFEQAQELLRREPSNCQPRLVLNVPDGTNFFDIKAEDFELVDYDPVKPQLKFD
                     LAI"
     gene            complement(114809..115768)
                     /locus_tag="ACL29Z_000126"
     CDS             complement(114809..115768)
                     /locus_tag="ACL29Z_000126"
                     /EC_number="2.7.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002919069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004340 - glucokinase activity [Evidence
                     IEA];
                     GO_process: GO:0006096 - glycolytic process [Evidence
                     IEA];
                     GO_process: GO:0051156 - glucose 6-phosphate metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family glucokinase"
                     /protein_id="HGR0068510.1"
                     /translation="MSQKIIGIDLGGTSIKFAILTTAGEIQGKWSIKTNILDEGSHIV
                     DDMIESIQHRLDLLGLAAADFQGIGMGSPGVVDREKGTVIGAYNLNWKTLQPIKQKIE
                     KALGIPFFIDNDANVAALGERWMGAGDNQPDVVFMTLGTGVGGGIVAEGKLLHGVAGA
                     AGELGHITVDFDQPISCTCGKKGCLETVASATGIVNLTRRYADEYEGDAALKRLIDNG
                     EEVIAKTVFDLAKEGDDLALIVYRNFSRYLGIACANIGSILNPSTIVIGGGVSAAGEF
                     LLQGVQKVYDENSFPQVRTSTKLALATLGNDAGVIGAASLVLQ"
     gene            complement(115895..116653)
                     /locus_tag="ACL29Z_000127"
     CDS             complement(115895..116653)
                     /locus_tag="ACL29Z_000127"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001042500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Ltp family lipoprotein"
                     /protein_id="HGR0068511.1"
                     /translation="MNKRLFLKMSLVTLPILALFSQPVLAEENIHFSSCKEAWANGYS
                     DIHEGEPGYSAKLDRDHDGVACELKNAPKGAFKAKQSTAIQINTSSATTSGWVKQDGA
                     WYYFDGNGNLVKNAWQGSYYLKADGKMAQSEWIYDSSYQAWYYLTSDGSYAYSTWQGN
                     YYLKSDGKMAVNEWVDGGRYYVGADGVWKEGQASTVSSSNDSNSEYSAALGKAKSYNS
                     LFHMSKKRMYRQLTSDFDKFSNDAAQYAIDHLDD"
     gene            complement(116703..117320)
                     /locus_tag="ACL29Z_000128"
     CDS             complement(116703..117320)
                     /locus_tag="ACL29Z_000128"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000766583.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HGR0068512.1"
                     /translation="MKLIFLHGLGQSAESWKEVRNLLTDYPSEAIELFPSGVSNYQQA
                     KERVYQHLAQETEPFVLIGLSLGAALTLELSSYDLPNLRALILSGCPLKLAGNILFYL
                     QLLIFKLLPKRVFEKQGADKTLMVGVSEELKTLDLTDIAGTCSYPTLLICGSKDKPNL
                     SSMKALHRLLTDSQFQIIPDGPHVLNKAKPKEFVEKTRSFLELLK"
     gene            complement(117321..119042)
                     /gene="pabB"
                     /locus_tag="ACL29Z_000129"
     CDS             complement(117321..119042)
                     /gene="pabB"
                     /locus_tag="ACL29Z_000129"
                     /EC_number="2.6.1.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001818774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046820 - 4-amino-4-deoxychorismate
                     synthase activity [Evidence IEA];
                     GO_process: GO:0008153 - para-aminobenzoic acid
                     biosynthetic process [Evidence IEA];
                     GO_process: GO:0009396 - folic acid-containing compound
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aminodeoxychorismate synthase component I"
                     /protein_id="HGR0068513.1"
                     /translation="MHRKTVIDFRTLGERYTFTQPIKELKTRNVEEVADLLAQVENYQ
                     TQGYYVVGYVSYEAAPAFEEKLAVHKVPLLGEYLLYFTVHDRVETSPIPLTYEDIDLP
                     SNWQEVTSAEDYEKAIAQIHHHLRQGDTYQVNYTVQLKQKLSANPFAIYNRMVVEQEA
                     GYNAYVEHDEMAVISMSPELFFEQNDRELTTRPMKGTTQRGVTDQEDLEQASWLEQDP
                     KNRSENMMIVDLLRNDMNRISEVGSEHVERLCQVEQYSTVWQMTSTIKSQLREDVDLV
                     EIFRSLFPCGSITGAPKIATMEIIKDLEPQPRGVYCGTIGLLLPNGRRIFNVAIRTIQ
                     LHKGQAIYGVGGGITWDSTWESEYREVHQKAAVLYRKQARFQLITTGEISQKNLLFED
                     QHLERLRKASRYFAFPFDAEDLGHKIEEECQDCEANRDYRLRISLSKSGEIEVNRQVL
                     TPLSTSFCQAQVCLQEAALNQSFTYFKTTHRSHLSLGEQEKIYHNKSGELLETSIGNL
                     VLKIAGKLYTPPIRLGILPGIYRQHLLETGQVEEKVLTLADLTQAEAIYGCNAVRGLY
                     ELSLEEN"
     gene            complement(119103..124556)
                     /locus_tag="ACL29Z_000130"
     CDS             complement(119103..124556)
                     /locus_tag="ACL29Z_000130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000473001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005576 - extracellular region [Evidence
                     IEA];
                     GO_function: GO:0004222 - metalloendopeptidase activity
                     [Evidence IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ZmpA/ZmpB/ZmpC family metallo-endopeptidase"
                     /protein_id="HGR0068514.1"
                     /translation="MFKKDRFSIRKIKGVVGSVFLGSLLMAPSVVDAATYHYVNKEII
                     SQEAKDLIQTGKPDRNEVVYGLVYQKDQLPQTGTEASVLTAFGLLTVGSLLLIYKRKK
                     IASVFLVGAMGLVVLPSAGAVDPVATLALASREGVVEMEGYRYVGYLSGDILKTLGLD
                     TVLEETSAKPGEVTVVEVETPQSTTNQEQARTENQVVETEEAPKTEESPKEEPKSEIK
                     PTDDTLPKVEEGKEASAEPAPVEEVGGEVESKPEEKVAVKPESQLSDKPAEESKVEPP
                     VEQAKVPEQPVQPTQAEQPSTPKESSQEDNSKEDRGAEETPKQEDEQPAEAPEIKVEE
                     PVESKEETVNQPVEQPKVETPAVEKQTEPTEEPKVEVTTVETREEVIPFETKEQEDDT
                     LKRGTRQVVQKGVEGKKQITETYKTIRGEKTNEAPIVKETVIEQPQDEIIKKGTKGLE
                     KPTLQWANTEKDVLKKSATASYTLTKPAGVEIKSIKLALKDKDGQLVKEVTVAENNLN
                     ATLDKLKYYQGYTLSTTMVYDRGEGEETEKLEDKQIQLDLKKVEIKNIKETSLMNVDA
                     EGNETDKSLLSEKPTDVSQLYLRVTTHDNKVTRLAVSSVEEVVVDGKTLYKVVAKAPD
                     LVQRRADDTLSEEYVHYFEKQLPKVNNVYYNFNELVKDMQANPTGEFKLGADLNAANV
                     KPNGKSYVTKPFKGKLLSNDGGRFTIHNIERPLFANIEGGKIHDINLANVNINMPWAD
                     KVAPIANVIKNNATIENVKVTGNVLGKDWVSGFIDKIDGSGKLINVAFIGNVTSVGTG
                     GNFLTGIVGENWKGYVERAYVDAHIKGKRAKAAGIAYWSQNQGNNFTIGSEGAIKKSV
                     VKGTIDVEKPIEVGGAVGSFTYHGSIEDTVSMMKVKNGEIFYGSKDIDDDPYYTGNHV
                     NRNYVVIGVSEGTSTYRYSNQHNRIKPITQSEADVKIAETAITADKFTITDPIVNKLN
                     ALTTRDNEYRTTQDYEATREQAYRNIEKLQPLYNKEWIVNQGNKLVEGSNLLTKEVLS
                     VTGIKSGQFVTDLSDIDKIMIHYSDGAKEELNVTRQESNVQQVREYSITDLDILYTPN
                     MVEKDRAQLMTDVKSKLSSVELESDGVRQLLVKRDTKKDANANSVGRQNGYIRDLFLE
                     ESFSEVKANLDKLVKQILENEDHQLNDNELAERALLKKVEDNKAKIMMGLAYLNQYYA
                     FKYDELSIKDIMMFKPDFYGKTASVIDRLINIGSAENNLKGDRTQDAYRGIISGATGK
                     GSLHDFLTYNMKLFTNETDINVWFKKAIEKNAYVVEQPSTNSAFANKKYRLYEGINNG
                     QHGRMILPLLNLKNAHLFMISTYNTISFSSFEKYGKDTDEKREKFKSEINKRAKEQVN
                     YLDFWSRLATDNVRDKLLKSQNVVPTPVWDNHNSPNGWASRHGHIDGKPDYAPIREFF
                     GRINKYHGYKYGYGAYAYIFAAPQPMDAVYFVMTDLISDFGTSAFTHETTHVNDRMAY
                     YGGHWHREGTDLEAFAQGMLQTPSVSNPNGEYGALGLNMAYERQNDGNQWYNTNPNDL
                     TTRAEIDNYMKGFNDTLMLLDYLEGEAVLNKANQDLNNAWFKKVDKQLRGASTKNQYD
                     KVRDLTADEKNITLNSVDDLVDNNFMTKHGPGNNVYDPTGFGTAYVTVPITAGIYGGN
                     TSEGAPGSMSFKHNTFRMWGYYGYEKGFLNYASNMLKNESRQAGHNTLGDDFIIKKVS
                     DNKFSTLEDWKKAYFKEVVDKAKAGFNPVTIDSTTYSSYDDLKNAFAAAVEKDKATLK
                     NGSVKSDNTVALKEKIYKKLLQQTDSFKTSIFR"
     gene            complement(124578..125141)
                     /locus_tag="ACL29Z_000131"
     CDS             complement(124578..125141)
                     /locus_tag="ACL29Z_000131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001006373.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01440 family protein"
                     /protein_id="HGR0068515.1"
                     /translation="MNETQIQRETRQVVEDVLEKTNLKQGALFVLGLSSSEVLGGQIG
                     KESSQEIGELIVETILGILGSRGIHLAVQGCEHVNRALVVERQVAEQFDLEIVSVHPT
                     LHAGGSGQLAAFKFMQDPVEVEFIKAHAGLDIGDTAIGMHVKHVQVPIRPILREIGHA
                     HVTALTSRPKLIGGARAHYPQDAIRKF"
     gene            complement(125257..126948)
                     /locus_tag="ACL29Z_000132"
     CDS             complement(125257..126948)
                     /locus_tag="ACL29Z_000132"
                     /EC_number="2.7.13.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000831084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA];
                     GO_function: GO:0004673 - protein histidine kinase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0007165 - signal transduction [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HGR0068516.1"
                     /translation="MKRSSLLVRMVISIFLVFLILLALVGTFYYQSSSSAIEATIEGN
                     SQTTISQTSHFIQSYIKKLETISTGLTQQTDVLAYAENPSQDKVEGIRDLFLTILKSD
                     KDLKTVVLVTKSGQVISTDDSVQMKTSSDMMAEDWYQKAIHQGAMPVLTPARKSDSQW
                     VISVTQELVDAKGANLGVLRLDISYETLEAYLNQLQLGQQGFAFIINENHEFVYHPQH
                     TVYSSSSKMEAMKPYIETGQGYTPGHKSYVSQEKIAGTDWTVLGVSSLEKLDQVRSQL
                     LWTLLGASVTSLLVCLCLVWFSLKRWIAPLKDLRETMLEIASGAQNLRAKEVGAYELR
                     EVTRQFNAMLDQIDQLMVAIRSQEETTRQYQLQALSSQINPHFLYNTLDTIIWMAEFH
                     DSQRVVQVTKSLATYFRLALNQGKDLICLSDEINHVRQYLFIQKQRYGDKLEYEINEN
                     VAFDNLVLPKLVLQPLVENALYHGIKEKEGQGHIKLSVQKQDSGLVIRIEDDGVGFQD
                     AGDSSQSQLKRGGVGLQNVDQRLKLHFGANYQMKIDSRPQKGTKVEIYINRIETS"
     gene            complement(126945..127682)
                     /locus_tag="ACL29Z_000133"
     CDS             complement(126945..127682)
                     /locus_tag="ACL29Z_000133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HGR0068517.1"
                     /translation="MTYTILIVEDEYLVRQGLTKLVNVAAYDMEIIGQTENGRQAWEL
                     IQKQVPDIILTDINMPHLNGIQLASLVRETYPQVHLVFLTGYDDFDYALSAVKLGVDD
                     YLLKPFSRQDIEEMLGKIKQKLDKEEKEEQLQDLLTNRFEGNMAQKIQSHLADSQFSL
                     KSLASDLGFSPTYLSSLIKKELGLPFQDYLVRERVKQAKLLLLTTDLKIYEIAEKVGF
                     EDMNYFTQRFKQIAGVTPRQFKKGEDR"
     gene            complement(127905..129017)
                     /gene="msrB"
                     /locus_tag="ACL29Z_000134"
     CDS             complement(127905..129017)
                     /gene="msrB"
                     /locus_tag="ACL29Z_000134"
                     /EC_number="1.8.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730371.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0033743 - peptide-methionine (R)-S-oxide
                     reductase activity [Evidence IEA];
                     GO_process: GO:0006979 - response to oxidative stress
                     [Evidence IEA];
                     GO_process: GO:0030091 - protein repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (R)-S-oxide reductase MsrB"
                     /protein_id="HGR0068518.1"
                     /translation="MNDKLKIFLLLGVFFLAITGFYVLLIRNAGQTDASQIEKAAVSQ
                     GGKAVKKTEISKDADLHEIYLAGGCFWGVEEYFSRVPGVTDAVSGYANGRGETTKYEL
                     INQTGHAETVHVTYDAKQISLKEILLHYFRIINPTSKNKQGNDVGTQYRTGVYYTDDK
                     DLEVINQVFDEVAKKYDQPLAVEKENLKNFVVAEDYHQDYLKKNPNGYCHINVNQAAY
                     PVIDASKYPKPSDEELKKTLSPEEYAVTQENQTERAFSNRYWDKFESGIYVDIATGEP
                     LFSSKDKFESGCGWPSFTQPISPDVVTYKEDKSYNMTRMEVRSRVGDSHLGHVFTDGP
                     QDKGGLRYCINSLSIRFIPKDQMEEKGYAYLLDYVD"
     gene            complement(129028..129594)
                     /locus_tag="ACL29Z_000135"
     CDS             complement(129028..129594)
                     /locus_tag="ACL29Z_000135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000759281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="redoxin family protein"
                     /protein_id="HGR0068519.1"
                     /translation="MKKWQTCVLGAGSLLCLTACSGKSVTSEHQTKDEMKTEQTASKT
                     SAAKGKEVTDFELMGVDGKTYRLSDYKGKKVYLKFWASWCSICLASLPDTDEIAKEAG
                     DDYVVLTVVSPGHKGEQSEADFKNWYKGLDYKNLPVLVDPSGKLLETYGVRSYPTQAF
                     IDKEGKLVKTHPGFMEKDAILQTLKELA"
     gene            complement(129614..130324)
                     /gene="ccdA2"
                     /locus_tag="ACL29Z_000136"
     CDS             complement(129614..130324)
                     /gene="ccdA2"
                     /locus_tag="ACL29Z_000136"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000509848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiol-disulfide oxidoreductase-associated
                     membrane protein CcdA2"
                     /protein_id="HGR0068520.1"
                     /translation="MGHIFFFLSVFLAGILSFFSPCILPLLPVYTGVLLDDKDGAQAS
                     SGKFSISVTSLLRTLAFIAGISFIFILLGYGAGFLGDLLYASWFQYLTGAIIILLGLH
                     QMEILHFKGLYKEKRLQLQGQGQNGKGYSQAFLLGLTFSFAWTPCVGPVLGSVLALAA
                     SGGSGAWQGAGLMLVYTLGLALPFLLLALTSSYILKHFRKLHPYLGILKKVGGFLIIV
                     MGLLVLFGNASILSQLFE"
     gene            complement(130535..131395)
                     /locus_tag="ACL29Z_000137"
     CDS             complement(130535..131395)
                     /locus_tag="ACL29Z_000137"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YihY/virulence factor BrkB family protein"
                     /protein_id="HGR0068521.1"
                     /translation="MKKWWKELIDKPLLKAFLHYYQASDSELTSVAVAYYWLISIFPL
                     LLVVVNILPYFQIPVGEFLGFMKDVLPPSLYEGMEKIAREVLTQPSTGLLSFSVLSAL
                     WSFSKSMNFLQKAFNKAYGVEKSRGLISHQMLSLLVSFGLQLLFAFALFLILFGQMIL
                     ALLAHYWTKDGIIYQALQGLAGPLIYALLFAILVMLYYFLPNLSNRKISYTLPGSAFV
                     LLVILGLLTLFSSYLNYYVHHLVDVRILGSVLLVVMMFWFILIAKIVILGAVINASMQ
                     SLKDPVFKKD"
     gene            complement(131574..133628)
                     /locus_tag="ACL29Z_000138"
     CDS             complement(131574..133628)
                     /locus_tag="ACL29Z_000138"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000421632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0006814 - sodium ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cation:proton antiporter"
                     /protein_id="HGR0068522.1"
                     /translation="MELLIYLILFLLVLIVSSTTNKLLPFLPLPLVQILLGIVIGLFL
                     PNTDFHLNTELFLALVIGPLLFREAEEADVTAILKHWRIIVYLIFPVIFISTLSLGGL
                     AHLLWFSLPLAACLAVGAALGPTDLVAFASLSERFSFPKRVSNILKGEGLLNDASGLV
                     AFQVALTAWTTGAFSLGQASSSLIFSILGGFLIGFLTAMTNRFLHTFLLSVRATDIAS
                     ELLLELSLPLVTFFLAEEVHVSGIIAVVVAGILKASRFKKITLLEAQVDTVTETVWHT
                     VTFMLNGSVFVILGMELEMIAEPILTNPIYNPLLLLLSLIALTFVLFVIRFIMIYGYY
                     AYRTRRLKKKLNKYMKDMFLLTFSGVKGTVSIATILLIPSNLEQEYPLLLFLVAGVTL
                     VSFLTGLLVLPHLSDEEEESKDYLMHIAILNEVTLELEKELEDTRNKLPLYAAIDNYH
                     GRIENLILSQENQDDQEDWAALKLLILSIESDGLEQAYEEGNISNRAYRVYQRYLKNI
                     EQGINRKLASRLTYYFLVSLRILRFLLHEVFTLGKTFRSWKDKEQSRLRALDYDQIAE
                     LYLANTEMIIESLENLKGVYRRSLISFMQESRLRETAIISSGSFVERVINRVKPNNID
                     EMLRGYYLERKLIFEYEEKRLITTKYAKKLRQNVNNLENYSLKEAANTLPYDMVELVR
                     RN"
     gene            complement(133640..133894)
                     /locus_tag="ACL29Z_000139"
     CDS             complement(133640..133894)
                     /locus_tag="ACL29Z_000139"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000361102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0068523.1"
                     /translation="MDKQYLHEKLDAMRQNFVESTHHERSVGVLDQAHMSKKMLKIKK
                     KLVALEMERCQRKIEHKDCSKIDQKIKEQKEIFESCCKKD"
     gene            complement(133887..134444)
                     /locus_tag="ACL29Z_000140"
     CDS             complement(133887..134444)
                     /locus_tag="ACL29Z_000140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000828405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HGR0068524.1"
                     /translation="MKRPLEMAHDFLAEVVTKEDVVVDATMGNGHDTLFLAKLAKQVY
                     AFDIQKQALEKTQERLHQAGLTNAQLILQGHETLDQFVTKAKAGIFNLGYLPSADKSV
                     ITRPQTTIEALEKLCGLLVKGGRIAIMIYYGHEGGDLERDAVLDFVIQLNQQEYTAAI
                     YRTLNQVNNPPFLVMIEKLERYRHG"
     gene            complement(134428..135385)
                     /locus_tag="ACL29Z_000141"
                     /pseudo
     CDS             complement(134428..135385)
                     /locus_tag="ACL29Z_000141"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002881980.1"
                     /note="This family includes YhcC from E. coli K-12, an
                     uncharacterized radical SAM protein.; frameshifted;
                     internal stop; Derived by automated computational analysis
                     using gene prediction method: Protein Homology.
                     GO_function: GO:0051536 - iron-sulfur cluster binding
                     [Evidence IEA];
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01212 family radical SAM protein"
     gene            135477..135836
                     /locus_tag="ACL29Z_000142"
     CDS             135477..135836
                     /locus_tag="ACL29Z_000142"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004249826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3397 domain-containing protein"
                     /protein_id="HGR0068525.1"
                     /translation="MGMILMKLASILLLILTLVVCIILTKLFRLKKLGRNFADLAFPV
                     LVFEYYLITAKTFTHNFLPRLGLALSILAIILVFFFLLKKRSFYYPKFIKFFWRTGFL
                     LTLIMYIEMVVELFLMK"
     gene            135988..136233
                     /locus_tag="ACL29Z_000143"
     CDS             135988..136233
                     /locus_tag="ACL29Z_000143"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HGR0068526.1"
                     /translation="MHIHYNTNQTTLPLEISSFLPQDHLVFTIEKVVNTLEEHHFYAF
                     YHAFDRPSYHPKMLVSTLLFVYSQGIFSGRKIEKWKS"
     gene            136233..136646
                     /locus_tag="ACL29Z_000144"
     CDS             136233..136646
                     /locus_tag="ACL29Z_000144"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0068527.1"
                     /translation="MTLDCLFIDGTKIEANANKYSFVWKKTTEKFSAKLQEQIQVYFQ
                     EEITPLLIKYAMFDKEQKRGYKQSAKNLANWHYNDKEDSYTHPDGWYYRFHHTKHQKT
                     QTDFQQEIKVYYADEPESAPQKGAIYERTLSKLES"
     gene            136615..136845
                     /locus_tag="ACL29Z_000145"
     CDS             136615..136845
                     /locus_tag="ACL29Z_000145"
                     /inference="COORDINATES: protein motif:HMM:NF025126.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HGR0068528.1"
                     /translation="MNERYQNLKAKECQALLSPQGRQIFAQRKIDVEPVFGQLKACLG
                     YKRCNLRGKRQVRIDMGLVLMANNLLKHSEMK"
     gene            complement(137094..143792)
                     /gene="bgaA"
                     /locus_tag="ACL29Z_000146"
     CDS             complement(137094..143792)
                     /gene="bgaA"
                     /locus_tag="ACL29Z_000146"
                     /EC_number="3.2.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000515226.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG-anchored adhesin/beta-galactosidase BgaA"
                     /protein_id="HGR0068529.1"
                     /translation="MGKGHWNRKRVYSIRKFAVGACSVMIGTCAVLLGGNIAGESVVY
                     ADETLITHTAEKPKEEKMIVEEKADKALETKNVVERTEQSEPSSTEAIASEKKEDEAV
                     TQKEEKVSAKPEEKAPRIESQASSQEKPLKEDAKAVTNEEVNQMIEDRKVDFNQNWYF
                     KLNANSKEAIKPDADVSTWKKLDLPYDWSIFNDFDHESPAQNEGGQLNGGEAWYRKTF
                     KLDEKDLKKNVRLNFDGVYMDSQVYVNGQLVGHYPNGYNQFSYDITKYLHKDGRENVI
                     AVHAVNKQPSSRWYSGSGIYRDVTLQVTDKVHVEKNGTTILTPKLEEQQHGKVETHVT
                     SKIVNTDDKDHELVAEYQIVERGGHAVTGLVRTASRTLKAHESTSLDAILEVERPKLW
                     TVLNDKPALYELITRVYRDGQLVDAKKDLFGYRYYHWTPNEGFSLNGERIKFHGVSLH
                     HDHGALGAEENYKAEYRRLKQMKEMGVNSIRTTHNPASEQTLQIAAELGLLVQEEAFD
                     TWYGGKKPYDYGRFFEKDATHPEARKGEKWSDFDLRTMVERGKNNPAIFMWSIGNEIG
                     EANGDAHSLATVKRLVKVIKDVDKTRYVTMGADKFRFGNGSGGHEKIADELDAVGFNY
                     SEDNYKTLRAKHPKWLIYGSETSSATRTRGSYYRPERELKHSNGPERNYEQSDYGNDR
                     VGWGKTATASWTFDRDNAGYAGQFIWTGTDYIGEPTPWHNQNQTPVKSSYFGIVDTAG
                     IPKHDFYLYQSQWVSVKKKPMVHLLPHWNWENKELASKVADSEGKIPVRAYSNASSVE
                     LFLNGKSLGLKTFNKKQTSDGQTYQEGANANELYLEWKVAYQPGTLEAIARDESGKEI
                     ARDKITTAGKPAAVRLIKEDHAIAADGKDLTYIYYEIVDSQGNVVPTANNLVRFQLHG
                     QGQLVGVDNGEQASRERYKAQADGSWIRKAFNGKGVAIVKSTEQAGKFTLTAHSDLLK
                     SNQVTVFTGKKEGQEKAVLGTEVARVRTLIGKEPKMPKTVGFVYSDGSREKLPVTWSQ
                     VDVSQAGVVTVKGTANGREVEAHVEVLAIAKELPTVKRIAPNTDLNSVDKSVSYVLTD
                     GSVQEYEVDSWEITEVDKAKLSVAGSRIQMTGQLAGETIHATLVVEEGNAAAPVVPTV
                     TVGGEAVTGLTSRQPMQYRTLSYGAQLPEVTASAENADVTVLQASAANGMRASIFIQP
                     KDGGPLQTYAIQFLEEAPKIAHLSLQVEKADSLKEDQTVKLSVRAHYQDGTQAVLPAD
                     KVTFSTSGEGEVAIRKGMLELHKPGAVTLKAEYEGAKGQVDLTIQANTEKKIAQSIRP
                     VNVVTDLHQKPTLPTTVTVEYDKGFPKALKVTWQAIPKEKLDSYQTFEVLGKVEGIDL
                     EARAKVSVEGIVSVEEVSVTTPIAEAPQLPESVRTYDSNGHVSSAKVAWDAIRPEQYA
                     KEGVFTVNGRLEGTQLTTKLHVRVSAQTEQGANISDQWTGSELPLAFASDSNPSDPVS
                     NVNDKLISYNNQPANRWTNWNRSNPEASVGVLFGDSGILSKRSVDNLSVGFHEDHGVG
                     APKSYVIEYYVGKTVPTAPKNPSFVGNEDHVFNDSANWKPVTNLKAPAQLKAGEMNHF
                     SFDKVETYAIRIRMVKADNKRGTSITEVQIFAKQVAAAKQGQTRIQVDGKDLANFNPD
                     LTDYYLESVDGKVPAVTASVSNNGLATVVPSVREGEPVRVIAKAENGDILGEYRLHFT
                     KDKNLLSHKPVAAVKQVRLLQVGQALELPTKVPVYFTGKDGYETKDLTVEWEEVPAEN
                     LTKAGQFTVRGRVLGSNLVAEVTVRVTDKLGETLSDNPNYDENSNQAFASATNDIDKN
                     SHDRVDYLNDGDHSENRRWTNWSPTPSSNPEVSAGVIFRENGKIVERTVAQGKVQFFA
                     DSGTDAPSKLVLERYVGPEFEMPTYYSNYQAYDADHPFNNPENWEAVHYRADKDIEAG
                     DEINVTFKAVKAKAMRWRMERKADKSGVAMIEMTFLAPSELPQESTQSKILVDGKELA
                     DFAENRQDYQITYKGQRPKVSVEENNQVASTVVDSGEDSLPVLVRLVSESGKQVKEYR
                     IHLTKEKPVSEKTVAAVQEDLPKLEFVEKDLAYKTVEKKDSTLYLGETRVEQEGKTGK
                     ERIFTAINPDGSKEEKLREVVEAPTDRIVLVGTKPVAQEAKKPQVSEKADTKPIDSSE
                     ASQTNKAQLPNTGSAASQAAVAGLALLGLSAGLVVTKGKKED"
     gene            complement(143880..144071)
                     /locus_tag="ACL29Z_000147"
     CDS             complement(143880..144071)
                     /locus_tag="ACL29Z_000147"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0068530.1"
                     /translation="MKIKEQTRKLAAGCSKHSFEVVDKTDEVSSKHGFEVVDETDEVS
                     NHIYGKATLTKFELDFRRV"
     gene            complement(144097..145572)
                     /locus_tag="ACL29Z_000148"
     CDS             complement(144097..145572)
                     /locus_tag="ACL29Z_000148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000338710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS galactitol transporter subunit IIC"
                     /protein_id="HGR0068531.1"
                     /translation="MDAIFDLIGKVFNPILEMGGPVIMLIILTVLALLFGVKFSKALE
                     GGIKLAIALTGIGAIIGMLNGAFSASLAKFVENTGIQLSITDVGWAPLATITWGSAWT
                     LYFLLIMLIVNVVMLAMKKTDTLDVDIFDIWHLSITGLLIKWYADNNGVSQGVSLFIA
                     TAAIVLVGVLKIINSDLMKPTFDDLLNAPSSSPMTSTHMNYMMNPVIMVLDKIFEKFF
                     PGLDKYDFDAAKLNKKIGFWGSKFFIGFILGIVIGIMGTPHPIAGVADADKWRLVIKG
                     WLSLGLTAGVSLELFSLIGSWFIAAVEPLSQGITNVATKRLRGRKFNIGLDWPFIAGR
                     AEIWACANVLAPIMLIEAVLLSKVGNGILPLAGIIAMGVTPALLVVTRGKLLRMIIFG
                     TLLLPLFLLSGTLIAPFATELAKGVGAFPEGVSQTQLITHSTLEGPIEKLLGWTIGNT
                     TTGDIKAILGAVVFLVFYIGIFAWYRKQMIKRNEEYAAKAK"
     gene            complement(145620..145925)
                     /locus_tag="ACL29Z_000149"
     CDS             complement(145620..145925)
                     /locus_tag="ACL29Z_000149"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000590575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HGR0068532.1"
                     /translation="MIKILAACGAGVNSSHQIKSALEEELSNRGYDVHCDAVMVKDVN
                     EDLMKGYDIFTPIAATDLGFEPGIPVIEAGPILFRIPAMSAPVFDNIEAAIKEHGLS"
     gene            complement(145963..146439)
                     /locus_tag="ACL29Z_000150"
     CDS             complement(145963..146439)
                     /locus_tag="ACL29Z_000150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000242196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HGR0068533.1"
                     /translation="MVLDYFFDKNLVFCLEADNQEHLFDQVATLLEEREIVTPTYREA
                     LITREKSFPTGLDMEFLGKDLPNVAIPHTDIVHNLAEKVVVVRLEKPVTFHNMIAPDK
                     EVEVSLLFFIINNSSSSQTNILAQLMDFFTGNGHLEDLSKISEPEKLYAYIAEATA"
     gene            complement(147066..153485)
                     /locus_tag="ACL29Z_000151"
     CDS             complement(147066..153485)
                     /locus_tag="ACL29Z_000151"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000750079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008236 - serine-type peptidase activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="S8 family serine peptidase"
                     /protein_id="HGR0068534.1"
                     /translation="MKKSTVLSLTTAAVILAAYAPNEVVLADTSSSEDALSISDKEKV
                     AENKEKHEDIHSAMETSQDTEEKKTTIIEEKEVVSKNPVIDTKTSNEEAKIKEENSNK
                     SQGDHTDSFVNKNTENPKKEDKVVYIAEFKDKESGEKAIKELSSLKNTKVLYTYDRIF
                     NGSAIETTPDNLDKIKQIEGISSVERAQKVQPMMNHARKEIGVEEAIDYLKSINAPFG
                     KNFDGRGMVISNIDTGTDYRHKAMRIDDDAKASMRFKKEDLKGTDKNYWLSDKIPHAF
                     NYYNGGKITVEKYDDGRDYFDPHGMHIAGILAGNDTEQDIKNFNGIDGIAPNAQIFSY
                     KMYSDAGSGFAGDETMFHAIEDSIKHNVDVVSVSSGFTGTGLVGEKYWQAIRALRKAG
                     IPMVVATGNYATSASSSSWDLVANNHLKMTDTGNVTRTAAHEDAIAVASAKNQTVEFD
                     KVNIGGESFKYRNIGAFFDKNKITTNEDGTKAPSKLKFVYIGKGQDQDLIGLDLRGKI
                     AVMDRIYTKDLKNAFKKAMDKGARAIMVVNTVNYYNRDNWTELPAMGYEADEGTKSQV
                     FSISGDDGVKLWNMINPDKKTEVKRNNKEDFKDKLEQYYPIDMESFNSNKPNVGDEKE
                     IDFKFAPDTDKELYKEDIIVPAGSTSWGPRIDLLLKPDVSAPGKNIKSTLNVINGKST
                     YGYMSGTSMATPIVAASTVLIRPKLKEMLERPVLKNLKGDDKIDLTSLTKIALQNTAR
                     PMMDATSWKEKSQYFASPRQQGAGLINVANALRNEVVATFKNTDSKGLVNSYGSISLK
                     EIKGDKKYFTIKLHNTSNRPLTFKVSASAITTDSLTDRLKLDETYKDEKSPDGKQIVP
                     EIHPEKVKGANITFEHDTFTIGANSSFDLNAVINVGEAKNKNKFVESFIHFESVEEME
                     ALNSNGKKINFQPSLSMPLMGFAGNWNHEPILDKWAWEEGSRSKTLGGYDDDGKPKIP
                     GTLNKGIGGEHGIDKFNPAGVIQNRKDKNTTSLDQNPELFAFNNQGINAPSSSGSKIA
                     NIYPLDSNGNPQDAQLERGLTPSPLVLRSAEEGLISIVNTNKEGENQRDLKVISREHF
                     IRGILNSKSNDAKGIKSSKLKVWGDLKWDGLIYNPRGREENAPESKDNQDPATKIRGQ
                     FEPIAEGQYFYKFKYRLTKDYPWQVSYIPVKIDNTAPKIVSVDFSNPEKIKLITKDTY
                     HKVKDQYKNETLFARDQKEHPEKFDEIANEVWYAGAALVNEDGEVEKNLEVTYAGEGQ
                     GRNRKLDKDGNTIYEIKGAGDLRGKIIEVIALDGSSNFTKIHRIKFANQADEKGMISY
                     YLVDPDQDSSKYQKLGEIAESKFKNLGNGKEGSLKKDTTGVEHHHQENEESIKEKSSF
                     TIDRNISTIRDFENKDLKKLIKKKYKEEDDFVTGGKRTVELDYKYDDKGNITAYEDES
                     ALEYETEKFDEIKSKIYGVLSPSKDGHFEILGKISNVSKNAKVYYGNNYKFIEIKATK
                     YDSHSKTMIFDLYANINDIVDGLAFAGDMRLFVKDDNQIKAETKIRMPEKNKETKAEY
                     PYVSSYGNVIELGEGDLSKNKPDNLTKMESGKIYSDSEKQQYLLKDNIILRKGYALKV
                     TTYNPGKTDMLEGNGVYSKEDIAKIQKANPNLRVLSETTIYADSRNVEDGRSTQAVLM
                     SALDGFNIIRYQVFTFKMNDKGEAIDKDGNLVTDSSKLVLFGKDDKEYTGEDKSNVEA
                     IKEDGSMLFIDTKPVNLSMDKNYFNPSKSNKIYVRNPEFYLRGKISDKGGFNWELRVN
                     ESVVDNYLIYGDLHIDNTRDFNIKLNVKDGDIMDWGMKDYKANGFPDKVTDMDGNVYL
                     QTGYSDLNAKAVGVHYQFLYDNVKPEVNIDPKGNTSIEYADGKSVVFNINDKRNNGFD
                     GEIQEQHIYVNGKEYTSFDDIKQITDKTLNIKIVVKDFARNTTVKEFILNKDTGEVSE
                     LKPHRVTVTIQNGKEMSSTIVSEEDFILPVYKGELEKGYQFDGWEISGFEGKKDAGYV
                     INLSKDTFIKPVFKKIEEKKEEENKPTFDVSKKKDNPQVNHSQLNESHRKEDLQREDH
                     SQKSDSTKDVTATVLDKNNISSKSTTNNPNKLPKTGTASGAQTLLAAGIMFIVGIFLG
                     LKKKNQD"
BASE COUNT        45169 a        33374 c        27780 g        47386 t
ORIGIN      
        1 cattgtgtac tatttttggt tcattttact ataataataa cgatactaga taatgaggaa
       61 aatgcaatgg caaacccaac tttcggagaa aaaaagcgaa tacagactat attgctcgct
      121 atggcgtata tgcagttatc cctaatcctg aacaaaaaca aattgttctt gttcaagaac
      181 caaatggtgc ttggttccta ccatgtggag aaattgaagc aggtgaaaat catcaggaag
      241 ccctaaagcg tgagttgatt gaagagcttg gtttcacagc agaaattggt acctattacg
      301 gacaagctga cgaatatttc tattctcgtc atcgtgatac ctactactac aatcctgcct
      361 acctctatga agcaacttct ttcaaagaag tacaaaagcc actagcaaag aagtacaaaa
      421 gccactagaa aactttaatc atattgcctg gttccctatt gacgaggcta tccaaaacct
      481 taaacgtggt agccataaat gggccattga atcttggaaa aaacagcata agattggcta
      541 atactcttcg aaaataaaat tcaaaccacg tcagcgtcgc cttaccgtac tcaagtatag
      601 cctgcggcta gcttcctagt ttgctctttg attttcattg agtataaatc aagcgacttt
      661 attcaaaaag tgctataata gaattagaaa atcggaggaa atattatgaa gcttatcaat
      721 acgacaaact cacactcgca actggtaaaa agtcagctag aaagtaccga tgcaaccctt
      781 gttgaggttt attctgcagg gaatacagat gttattttta cccaagctcc gcttcactat
      841 gaaatcctca tctcaaacaa acaccgtgct attcgtgagc ctgaaatcga aaccattcaa
      901 gaatttttct tgaaacgtaa aattgataag acctctgttg atgaagccaa tatcaagaca
      961 ctctactcag agaaattaat tggaatttca atcccaatca agtaagaaaa ttgagtaaaa
     1021 actcgatttg agagaaagtc caataagtct ttccataaca aaacgcatag taacaagagt
     1081 ttctacaccc actattatgc gtttttatca ttttgaaatc tactgctaat caatgaagaa
     1141 gcaaagatca aactaggcag ctagttacaa gttacgtaag cgcgtcataa caaggtatct
     1201 atcctaattc cccaacttcc agtatactag ataaaaaata attatcggag gaaaggtatt
     1261 gtactatgat aattcaacta agtgatttag gtcaagttca ccttgtttgt ggtaagacag
     1321 atatgaggta gggaatagac tcattagcct atgtagttaa aacccacttt gaattggatt
     1381 ctttctccgg tcaagtcttt ctcttttgtg gtggacgtaa agaccgcttt aaaacccttt
     1441 actgggatgg tcaaggattt tggctactat ataaacgctt tgagaacgga aaactgactt
     1501 ggctaagtac agaaaaggat gtcaaagctc tcgcacctga acaagtagat tggctgatga
     1561 agggcttttc tatcactccc caaatatagt agattgaaac tagaatagta cacctctgct
     1621 tctaaaatat tgttagaaat cgatttgact gtcctgatcg atttgtcctg ttcttgtttc
     1681 gttttactat agaacgattt gaaggcgttt atgatattta gctgtacgag agtcttttaa
     1741 aagtgttttg atggtttgga tttcttcttt aattgatttc atattactat tgtataatgc
     1801 tttttgattt tagtctagta taaatagcga gaaatatcta tcctatcttc tagaatgtct
     1861 tccaaacgag aaaactctcg taaacaaaga ggttttagag gcctatttac cgtggactaa
     1921 agttgtacaa gaaaagtgca aataagaaat ctccagatta ggaactatcc gtgagttctc
     1981 tagtctggag atttttcaat agacttcgtt attggacggt taccaagtta ctcaaagtac
     2041 agatttgaag ctgcagataa gactgacgaa atcactttaa tactaaatga aaatcaaaaa
     2101 gcaaactaag agcctcaggc tgtacttgag tacggtaagg cgacgctgac gtgatttgaa
     2161 gagattttcg aagagtataa aacactgttt tgaggtggtg gataaatcgg ctgggcaaaa
     2221 actcaatctc aggagaaaat gaagtaaatc tccccacaac tatagaaaaa gatttgattc
     2281 tgctcctcac acaataaaat ctttttcttt tattaaaaac gaatcgtttc acgtgttttc
     2341 tcatatgagg taacaaagcg attggttaca ccaggctctg ccacttccaa tgcttgagaa
     2401 atcttgtcaa atgaagcgtg ataatcaaat tctttttcaa aaatatctaa agcttcgtta
     2461 aatgcttctt gaatgcgttc atcaaatgag cgatagcggt tagaatattg caagagttgc
     2521 tctgtcaaag ttgcatattg tacaatatta taagtttccg tttctaaagc ttccatatca
     2581 ttcgttgcaa tttcaagaac tcgggtaaca gattcaatgt taatcatttt ttgttctaac
     2641 tcaaccatta aatcctcggt attattgctt gccgtaaaga ataacttcaa gaaagtttgt
     2701 ggaatacctg gcagattgcg tttttccatg tatcgcttga tagtatggag acgattgaca
     2761 taaacattgg ccttttgacg tgcattaata tcatctttct caatttgtgt caggcgctca
     2821 ctaactgaaa tttgctcatc ttcaatatct tttagttgag tttgtaaatc ctcaagattt
     2881 tcttcaagaa ctgaataagc ttgggttggt tcttcttgat ttgaagttac ctcaacaata
     2941 gctgcctcaa aactctctaa ttctgtctga atacgacgaa catggcttgc agctgtctca
     3001 ggaagtaaat aggtcttgtt caaacgtgca atatcttctc ccaataaagt attattctct
     3061 ttcatatgtt gaaggtaagt tggaagagtt gcaagtagat tttccactac tttctgagca
     3121 gcaatttctc gagtaaaaat atcatacaag gcattgattt cctcttgtgc ctgtccattc
     3181 tcatattcgg cattatccaa ttccaactga cgaatattct cttggttttt cttgaatgct
     3241 tcataaagca agtggaaacg cgcttcaata tccgtttcaa caaaatgata attagcatca
     3301 attagtttac gataaccggc ttccaaatcc tgtaattgat ctggcaattc tgtagaaagc
     3361 gtcgtaacca aggctggaac acgatccaca atatgactta aggccaaaat gtgattttct
     3421 gtattatcca aaatcactgc ggcttccaca gggtcacccg atgaattcaa ggttacaaat
     3481 tgtgaaaatt cagattggat attttctaat tgtttttcaa tttcatccaa ggcttgacca
     3541 tactgttctg aattttcagc aactctatgc tgaagttcct caaataaatc caaagcatga
     3601 agaacacgac cactattttt agattcttgc ttctctaagt ctgccaaagc attgcgaatt
     3661 gccgcaatat cttcttcaat caaagtaatt tgactctcaa tttggtcaat ttgatgactg
     3721 gtcttgagaa aacgaaatga atggttataa ccttctgctt caaagagatt attttcaata
     3781 tcggcaaaag agttgagaga taaatcgacc catttttgat tccattcacg gaaagccact
     3841 tgactttgtc caatcaagtg catatttttt acagcttcta cttcatcatt tactggaaga
     3901 ttgtatagtt cttcttttct ttcttctagc gcctctaatc tcccctcgtt tcgcttacgt
     3961 agaaagattg ccactacata agccagaact aaaatgactg caattgcaac cattaaataa
     4021 attagttgtc cattagacat atcaaactcc ttttttactt gaaacaatcg taacgattat
     4081 atcatatttt ttagaccaag ggaactactt ctccctattt tttagacatc aagtgtacta
     4141 tagacagcat tttcttcgat aaactcacga cgaggctcta ctcgatcccc catcaacata
     4201 tcaaagattt tatctgcttc tgcagcatca tctacagaaa ctctagccat caagcgatgt
     4261 tcgggatcca tggttgtttc ccacagctga tgatcgtcca tttcacctag ccccttataa
     4321 cgctgaatag tcggtttggt acgaccttca ctataacggg ctaaagcttc ttggagtttg
     4381 atttcttgat ctgcacccgg ctggatatat tctttaatct cgcttccaac cttgacacca
     4441 tagattggtg gttgggcaat ataaacataa ccagcttcta ggattggttt catataacga
     4501 taaatcaagg ttaaaagaag ggtacgaatg tgggctccat cgacatcggc atcggtcatc
     4561 aaaacgagtt tttggtaacg ggctttcgaa acatcaaatt ctgcgccaaa tcctgttccc
     4621 atggctgtga aaagactacg aatttcttcg ttagctagaa tcttatccat acttgctttt
     4681 tcaacgttca aaatcttacc gcgaattgga aggatagcct gaaactcacg gttacgacca
     4741 gatttggctg atccaccagc tgagtctcct tcgacgatga agagttctgt ttcagcaggg
     4801 ttattagaag aacagtctgc tagtttccct ggaaggttgg aaatttccaa accagatttt
     4861 ttacgtgtga cttcacgcgc acgcttggca gccacacgag ccttggcagc taaaatccct
     4921 ttttccacga tacgtttggc aatctgtgga ttttccatga ggaaatcgga gaaggcttca
     4981 ctgaagaggc gattggtaat cttgaccact tcgctatttc ccaatttggt cttggtttgt
     5041 ccttcaaact gtggatttgg gtgtttaact gagataactg cagttaagcc ttcgcgaaca
     5101 tcttcccctg ttaggttgtc ttcattgtct ttcagtaact tatttttacg agcataatca
     5161 ttgataacac gtgtcaaggc tgtacggaaa ccttgttcat gcgttccacc ttcatgtgta
     5221 tgaatattat tggcgaaact catgacattt tcatggtaac cagttgtgta ctgcatggct
     5281 acctcaactg tgatatcatc catctcaccg tctgtataga ttggtgtatc aaagattaca
     5341 tccttgttct cgttgatata ttcaacgtaa ctagcaatcc caccttcata atgataatgc
     5401 ttggtttgtt ccaaaccttc acgcttatct gtaattgaaa tttgaagacc gcgatttaga
     5461 aaggccaact cttgaatccg tttatttaat ttatcaaaat caaagattgt tgtttcagtg
     5521 aagatttttg ggtccggtgt gaagtgaaca gttgttcctg ttttatccgt atctccaact
     5581 atttcaagat ctgcgacaac atgaccacga cggtattctt ggtaatgaat cttaccattt
     5641 ttgtgaacat gaacgtctaa ttgagtggaa agggcattaa ctactgacga ccccaccccg
     5701 tgaagaccac ctgaaacctt gtatccacca ccgccgaact ttcctccagc gtgaaggact
     5761 gtaaagacgg tctcaacagc aggacggcct gttttttcct gaatatcgac tgggatacca
     5821 cgcccatcat ccacaacagt aatcgaatca tctggctcaa taaaaacttg aatatggctg
     5881 gcaaatcctg ccaaggcctc gtcaattgag ttatcaacaa tttcccagac tagatggtga
     5941 agaccttctt ttgaggttga tccaatgtac atccctggac gcatacgaac agcctctaag
     6001 ccctctaaaa cttgaatttg actggcatca taatcctgtg cctgcagatt tttgatttct
     6061 tctgtcatct tattcctttt tcttatatgt ctaatacttg tcttaaattc acgatactgg
     6121 taaacaagtg ggtatcaagt cctgcagctt gacctgcttc gatatcaatc ggccgatcac
     6181 caatgacaag accagagcta atctgatact tttctcttaa ataaagcatg gattcgggat
     6241 ttggctttct cttaaagcct gagctagaag tcaccacttc tgtaaaataa gctgctatag
     6301 aggttttttc taaaatttcc aaaacctgat catttcgatg agagaccaaa aaatgacggc
     6361 caccttgatt tgaaatgact tccaataggt cagaaactcc ttcaaataaa atcgggtgtt
     6421 caagctctct ggcttcattt tccttgtact tttctaaaaa attctctaaa ttgggagcga
     6481 atgtctcaat cgcaaaagga gtagaaacct ttaaagcttg atagacactg tcatggtctt
     6541 gtgtgatacc atacagtgcc aatgtttcaa caaatgcagc tgttgaagtt tcataattat
     6601 ccagtaaagt tccacctaaa tcccagatgt aatcgtgata tttcataccc ttcattatag
     6661 cattttttta tgaaaaaagc gatgatttcc ctgagttttc cacataaaaa acgagagaat
     6721 aactcccgtt ttactgattt ttaccaaaga catcttgata gagcattcct gttcgtaaac
     6781 tctctgcgtc ccctcctagt tgctccacca actcgtaggc aaaggcaagg gctgttgaag
     6841 gaccccgact ggttgtcaac tgaccatcta ccactactgt ttccttgaca tagtgaccat
     6901 caaggatttg ctcttgaacg ccgtcataac aagtgtatcg cttatttttc aatatctctg
     6961 cttgattgag ggcaattggt gccgcacaaa tggctgctag tttcttccct tcttgctcga
     7021 agctttgcaa ttcttgaatc aaggtctgat tatcacgtaa atgtgcagaa ccaggcatac
     7081 ctccaggaag aacaatcata tcatagtctg ataaatctcc atcaaagaca tgatctgctc
     7141 ttacttggat tgcatgcgaa cccgttactt gctcttcaaa accaaccata tcacatgtga
     7201 tattggctcg acgcaagaca tctacaactg tcaaggcttc aatttcttca aagccctgag
     7261 ctaatataac tgctactttt accatgattt tctccttatt taatttgttt taatacaacc
     7321 tttttccgtt tgaatggaac ttttccgctt ttttcttcag ctagattagt ctggtaactc
     7381 atcgataaaa gcaaaccaac accaatcaga ttactgataa tagctgatcc cccttgcgaa
     7441 atgaaaggca agggaatccc cgtcaaagga agtagtccag tcacagcacc gatattctca
     7501 aagatgtgga agagcaacat cataatcaaa cctgtggaaa tataagtgta gaactggtta
     7561 tttgatttaa gagtaatctt caacatacgg taaatcaaca tgagatagag ggcaataacc
     7621 aggacagagc caataaagcc aaaatcttct gcaataaccg taaaaatcat atctgactct
     7681 cgaactggga taagcagatt cgaagcatta aatccctgac caaataagcc accactccca
     7741 atggcaatct gcccttgagc ctgctggtaa gtcgttgttt gggcaaactc aaagggattg
     7801 agccaagcca aaatccgatt gatttggtag gtcggcattc caatctggtg aagaaaagct
     7861 cgtccgtcct tgctaataaa gatagctaag aaaccagcaa ctcctgttac agcagtcaca
     7921 aatactggga taataatttt ccaagaaacc cctgataata aaacgattcc tgagaaaatg
     7981 gctacaaaaa ccaaagccgt ccccaagtca ctttgaagtg ctaaaagaac taggactgga
     8041 atggtaaaga gaatcatcca gaaaattaac aaaaagtcca gcggaaccgt gcgtctccat
     8101 tccttatgtt tctttgtaaa ttggacaatg acacgagcca acatgaggat ataggatatc
     8161 ttcataaatt ctgacggttg gaatagggta attccattta ttgataccca gtttttggca
     8221 cccgttgatg caactaagct tggattataa aatacaatcg gcaagatcat aagtcccaag
     8281 cctaaaatat atagaaaggg ggtcaccttc caaagaaatt ctgtattaaa gagcatgacc
     8341 acaaaaccaa tcacaagccc caaggcaatc caggcgacct gctgccctaa aatgggcaga
     8401 atattattgg gataatcatg actaacggct atatagatag ccaccacacc gatgaccagt
     8461 agaaaaaata ctggcaagag caaactataa tcgactctag agtcgagaga acgtttcata
     8521 tatactaacc ttatactttc atacaatact atttatcaaa gttcattaaa aaatctatca
     8581 atagcctcgt caacttcgga tcgagagatg gttttaatag tcgcttcttc tgctagagat
     8641 gctactattt gtttgccgta tcgttttccg atgattctcc tatccaaaat aagagttaag
     8701 gaacgttggt attcacgtct catacttctt cccaaagcct gttttaaacg aataatggcc
     8761 attggcaatt gataatcata aaaggcattt ttcccttctt gattcagttc ttgattaatc
     8821 tttttcgtca agggttcttg aggattttgg aaaggaagcc tcggtacaac ttgaatcaca
     8881 aaaggatggc ttgaaaaatc aactccctcc cagaaacttg ctgcaccaag caagatttgt
     8941 tgttcacctt tttcaaagcg tttctttagc tgatgaacat ccccattttt atactgggcc
     9001 aagtggctaa ctgtaagtaa atccgatact gctagaagca tgtctttagc agtaaagaga
     9061 accaaaatcg gttgctggaa agcttgaatt tccactagta aagcagctac ctctctggca
     9121 tagacttcta aggaggtttc tgttaccaga gggaaatctt tgaccataac cacttcttgt
     9181 tcctgttttc cccgagattc aatcttgaca aatttggctt caggatagcc taaaaggtct
     9241 gccaaagaaa ccctctgact aatctcaaga gtagccgata ctcccaagac ttggcaactc
     9301 tcaggaagta aagaggacag aagagtacgg catgattttg tagaagaaat ctgaattttc
     9361 ttttgactcg tttcagttac ttcaagccag taatcacctt cagctgtaaa atagcgaacc
     9421 agctcatcaa agccttctac ttctaattct gaaaaatact gatggagatt gtccagagaa
     9481 tctaagatat ttttcctaga tttaccagac tgaaattgtt ctatcaagta gagacactca
     9541 aagcgaatac tttctagtat ccgttgttga accctgtttt cttctcctac taaagcctta
     9601 tcaattaaat cgataataga ttgtatatcg taggtctctt gaagcagatt ttctagagct
     9661 aacaaaatct tttggacttc atcaataatc agtaaacggt cactgacaaa ttcaggatta
     9721 tcttcaagtc tggtcacgag ataggcatga ttagtcacta aaagcttgca agtctctgcc
     9781 ctttcttgac tacgtttcca aaaatcttcc gtcacaaata agctctggga tgataaattc
     9841 ccatcatgac gaaggtctgc tagaaaatgt tggtaacggt agagttgccc gatttcatcc
     9901 aaatctcctg tctctgtctc agtaagccag accaagactt gcattttaaa gcgtctaaat
     9961 aagcgatttt catcattttc ctgcaaggaa tgataaaagg catccaactt cagataattt
    10021 tgtggtccct ttaagctatg aatatctgta tggaacactt ccttgaggcg tttaccttct
    10081 tcttccatga tttgattttg aagaatcttt gtcggaacac taagaacaat ttgtcgctct
    10141 ttggattgag ataaagcggg taagagatag ccataggttt tcccaatccc tgtcggcgct
    10201 tgaatcagag agacaggttc atctttcaat agcaagccaa cctctttagc aaaactttct
    10261 tgttcctccc tcacttcaag gttcaacaga gaaatatttt tagaaaagtc ttgagatagt
    10321 tttcgtggct ccagagaagc tgccgttttc ttaaaataca gaccttgaac ttggaccaaa
    10381 tctggagaac tcaggataga ttggttgcga taagtttcct caataaccag gtaggactca
    10441 tataggagag cgtcagccat ttccagcaag cgttccaaga gacctttagg aagctgagtc
    10501 atcttttcca gtaaaaaaag aagtaattct gctgtagctt gagcatctga aagggctgtg
    10561 tgtgcgtgtt taagaggaat tcctaattct cgacacaaaa tcggcaagct atatttttcc
    10621 agttcaggga aaaagacctg ggccaattcg accgtatcaa cacgagggtt tcttagctca
    10681 tagccttcaa aaaataaatt ttccgccaag agattagcat caaactgaac attatgggct
    10741 acaaaaatcc catcctccac caagtcaaat atttttctgg caacttgcga aaaatcaggt
    10801 gcttgcgcca gacgttggtc tgtcaatcct gtcagttctt tgatatgagc atccaagggt
    10861 tcatgtggat tgacatccgt cgtatagtga tcgacgattt ctccgtcctc aatcacgaca
    10921 attcccactt ggataatttt agccttacta cctgtgctag ttgcctctaa atccaccaca
    10981 acatagcgat taccaatcgt tttcattata aaaaattata ccaaaaaaag ggccatttgg
    11041 cacctgcaaa cataggataa ttttcaaact caagaacact acttttctta aaaatcccat
    11101 cgaatagagc attctagcct gctgattttt taaaatagtg aagaaatacg aaaaattgag
    11161 agaagaaatg ttttcatctt ccttctctca acgaatcatg tattttattt aaccatgtca
    11221 ggatcgtagt cataaaatcc tgtatcaagg aaacggtttt tagggtgaag tttacgaact
    11281 tcttcatcca gcaagaaggc ttggtcatgg ctaaagttgc cctcttgaat caagctacgc
    11341 gcttggataa agagttttgc aatctcaaca aagttctgac caggagtgta gagcccttct
    11401 agtttccagc gagtaaagcc atgctccacc aattctgtta atttgatcat caaatcaagg
    11461 tcattgttgg caaagatatg ggtcccatga ttatcttcaa aaatggaata gtggctctct
    11521 ggatcacttg gctcagccaa gaagaggtca cgtttatgcg tcttttcatc atcgatatgt
    11581 gtaaagttat agtagttttg taagagtgga cgtttagaat gatggatgac gctagcaccg
    11641 taaaccaaaa cttcagcagg aatttccaaa atctctggca ttttgaaaag ttcagctgat
    11701 ggaatttcac gcgccaaaac agcctcagat gcgccagcct tttgtcccca gaagttaatc
    11761 tgacgactgc tagttaccat ggttgaagca tcgtagatgg tcttaaatga ataactatcg
    11821 cggttaacta cgtaaaagac gcctgcatcc ccaatcgtaa tatagtctgt cttgatttct
    11881 tccaagaagt ctaagaaagg cttgatacgg tccatcatat cttggtgcat gagagcattg
    11941 accgcaacga tcaattcctt accagcatca tgaaccaact tagcgatttc acgtaattgg
    12001 tcataactaa aggtcgttgg cagacgaagg ccaaaatctt tctcaccgac atagatacgg
    12061 tctacgccag cttcgagtag ttgttcaact tgttcaatac tttcagcagt tgctgtaatg
    12121 acaatctttt ccataagaaa aattatacca catttctcca aaatcatcca tgctttgaaa
    12181 atgaaaaggg actttattct ttttgtaacc tttctgtaat aattctctgc cgaaaaaatg
    12241 ataaaatagg tatgtactgt taaggagaga attatgcccg taagaaaatt acaatcctat
    12301 gaggtagact atcaagaaga attaaaccag cagcttcctc attaccaagc ttatacacct
    12361 gaagcgcaat ctgatgccaa tctcaaggaa atcctatttt ttattaatat cgctgttttt
    12421 tgtatctgta ttgctatctt tagttttatc tttttagcat taaaattatc aactgctctt
    12481 gcctttgccg cagcaatcgg attcagctta cttgttttaa aagttcaacg gtctattatc
    12541 aaacgaaaac gtagaagata aatccaaaat atcgccccag ttggagcgat atttttattt
    12601 tttcttttta gatggtgtct gaatggcaat cttcacttca aagattgttc ccttgggttt
    12661 attatctttg acagtaacag ttccttttag agcatctaca atttgcttgg ctagggataa
    12721 tcctaaacca aaaccacctt tttgccgagt tctagccttg tctactcgat aaaaacggtc
    12781 aaaaattttc tttttatctt ctgtcgaaat accgattcca ttatcagaaa caagtaaata
    12841 aagattgcga tcggtcgccg agataagaaa atcaatttca ccatcctcct cagtatactt
    12901 gacggcatta tcgaaaagaa tggtcatcag ttgtttcaga agaagctgat ctgtgacaat
    12961 tgttcgatgg atacgatttt caaaacggaa gacacgatta ttttccgaag caatcatctc
    13021 gtagtttgtg aaagttgtat taaaaaagct agttggaact tctgcaagct ccggcttaat
    13081 cccatcatct ctccgagcta agttcagcaa gcttgtcgtt aaaaaacgca tatttcggac
    13141 ttcttccaaa ctcgatgcaa tgctttcgct cacatccata atggtagctt ctggcttacg
    13201 aaaaagggtc tctaagcgat tttgcaaaac tgcgagtgga gttcgtaact catgactggc
    13261 attttccaca aaagactgtt gcttctgcat actctcaagc aggggcctaa cactgaccct
    13321 agctagatag agactggcaa gtaaagacaa aatccagaaa ctagccatca cgaccacaat
    13381 caattgctca tgcttttgac tagcctgttc caactgactg gtattaatca agacagcagc
    13441 atacttgata ttggttgaaa ccgaactaat attggtctcc atcaaaatca cacgatagat
    13501 ttcttcctgc ccatagctat taaaaacctg aatctggtag atatgtccta gttctttctt
    13561 ttctaactta atcttatcca agcccaaaaa tcgatttcca gaaagaagtt gagtaaagtc
    13621 tttatcaaag agaatgactt ccgtattgga actgacatta ggttttattt ctactttact
    13681 agcgtccgcc ctagcatttt ctaaatcttt aatctcttct gttgccctat ttatagccag
    13741 ctgaataact gcttgaggat tttcactcag tccatgaagc ttatcgtcca ccgaagtata
    13801 aagactcgaa tgcatgactt gtaaaataat cagagtcatt gtagaaaaaa tcagggtgaa
    13861 gacaccgaag ttgcggataa aataactaaa gtcatccgca taccatgttt ttttaagttt
    13921 actgaacatc ttttaaaaga tacccaacac tacgcaaggt ttgcaaattc tctgcaaaag
    13981 tggttccctt taatttctta cggacttttg aaacatagac ttcgacaacc gaaatcgttg
    14041 tatcactatc aaatccccat agacggtcaa aaatctgcgt cttaggcaaa atcacatttt
    14101 gattttgaag gaaataaact agtaaatcga actctttccc cagcaattcg acaggagtat
    14161 cttcaacttt aacggtattg gttgataaat taaccacgat attcccataa gtcaaggtgt
    14221 tttcattaaa cttccctgaa cgtttgagaa gggcctgaat ccgcatttta agttcttcta
    14281 ggtagaaagg tttggtcaga taatcatccg ctcccagttc aaatccatgt cccttgtcat
    14341 ccaaactttc cttggcagtc ataatcagaa ctggtgtcgt aattcccttt tcacgcaatt
    14401 cttttaagac ttggaaacca tttttttctg gcaacatcaa atccagcaaa atcaaatcat
    14461 agacaccact ctcagcttcg tagagacctt cttctccatc aaatacctgc ataacatccg
    14521 caaaatcgtc taaaaagtca aatactgaat ttgacagacc taggtcatcc tcaaccaata
    14581 agatttttat catgagaaac tcctccttat taaaactatt ataccaaatt tgccttaaaa
    14641 aaaactcaac tctctgcatt ttacatgaga tagctgagtt ttctttttat tttaggctta
    14701 tttatgcatt tccgtattga agaacaactg cttcgactgc agctttttca cggctaatca
    14761 agtcaacacg tgctgcaatt tccttgattc ccataccgat gttacggcta agagcaaggt
    14821 cagaaagttg cagctcaaag aactccttgt attccgccaa gcgttgctga gtcttaaata
    14881 catgagcagg aaggataaca aagctatcaa agctcatatc tcctccaagg gctgccttaa
    14941 tccaagccca gttttcacgc gcccaagacc aagctgtttt ctgagttgct tgatgagcta
    15001 ggaattggta ataccaagca gacaagtcct gtggtttgac cacaaatttg tccttccaag
    15061 aagtaatcaa gttttggata ttatccgcat ctgtactgta tgcaagagct gctgccaact
    15121 ggcgtttaaa gacagcatct gttgcgtgag tataagtatc aagataaagt gctaacaagt
    15181 ctttagtctc atgatgtttc atctcattaa tcagaacttg tgaacgaata gctgctggga
    15241 gttctgcaag attctccttg tgtgttgcga agatttggct agcgacttga cgagcttctg
    15301 catcatttga gcgaatcatc atcgaaacag ccagctgacg aaccaattca tcctcatctg
    15361 attctccgtc tttagcttca aaaccaagac ggtcatagtt atgacgagcc aatttagcaa
    15421 ccagtccttt gaaggctgtt tcagcatccg ttccttcatc aataaagcgc tcaagggctg
    15481 aaatcacttg agaaacagct gaaaccacca gataagactc ttccttagca agtttatcaa
    15541 gaactggaag caagtctgca taagaaatgt gccctgcctc agccaacaaa cgacgttctt
    15601 gaacaatttg cagtttgctt gtgttatcaa gtgtctctag ctcagcaaga acagcttcta
    15661 acaagtctcc ttgatagtcg gtaatatagt gggcagtatt ttcagtgttg agacgaagag
    15721 ctccttcatt ttcagcaaga agagctgcgt agccagggat ttcgatactt tcagtttcga
    15781 gtgtatcagg caagcctttc cagttgctat tgaggggcac cacccagaga cggttcttgt
    15841 cttcgttctc accgatgaag aattgttttt gtgaaatctt caagacatca ttttcaactt
    15901 tgacagtaag aactgggtaa ccaggctgtt ccaaccaaga atccatgaag gctgcgacat
    15961 cacgtcctga cgcttgacca agggcatccc aaaggtcact accaatggtg ttgctgtatt
    16021 ggtgtttttc aaagtaggca tgcaaacctt tagcaaaatc agcatctcct agccaacggc
    16081 gaagcatgtg catgagacgg cttcctttgg catagacgat agcgccgtca aagagtgtat
    16141 tgatttcatc tggatgttta acttcgacgt ggacagactg aacgccatca gtagcgtcac
    16201 gttcaagagc aagaggtact ccacctgttt ggaaatcttc aaagatattc cagcttggtt
    16261 cgatggtatc cacacagacg tattccatca tattagcgaa actttcattg agccaaaggt
    16321 catcccacca tttcatagtc acgaggttcc caaaccattg gtgagccaat tcatgggcca
    16381 caacaagggc aacttgttga cggctagcaa atgtagagtt ctcatcgaca accaagtaaa
    16441 cttcacggta ggtcacaaga ccccagtttt ccatagcacc agctgagaag tcaggaaggg
    16501 cgatgtggag agattgagga attggatact taactccata gtaatcttcg taaaactcga
    16561 tagagcgaac agcgatatcc agtgagaaat caagatttga aagtggatgt gctttggttg
    16621 agtagacacc taccagggta ccatttttag ttttagcggt caccccttgc aaatcaccag
    16681 caacaaaggc caacaagtaa gaagacatgc gaggtgttgt ctcaaacttc cagatacctg
    16741 tttccttacg gttttcaaca tcgatttctg gcatgtttga caaggccaat tcaccttctg
    16801 cttggtcaaa gcgaagagag aggtcaaaag ttgctttggc ttcaggctca tccacacatg
    16861 ggaaagcttc gcgcgcaaaa tggctctcga actgagtaga caagacctcc ttcttgactc
    16921 catcaactgt ataataagaa gggtaaatcc ctgtcatgtt gtctgtaatt ttaccagaaa
    16981 aggcaagaac caattcaact tgaccagcct cagccaattc gatatgaagg gcttcattgt
    17041 catggtcaac tgtaaatgga cgagcttgac ctgcaacttc tacagaggtg atttccaagt
    17101 ctttttggtg gagggagatg cggtcactct gtgcttgacc agtgatggtc actttcccag
    17161 aaaaagtctt ggtctcacga ctcaaatcta aaaataaatc ataatgttca ggaacaaatt
    17221 gcttaataaa atgttcaact gcttgcatag ttttctccta ttctaagttt aagagctgct
    17281 gctcttcttc aaacaaactt attatatcat attttgctta aaaaaaaagg attggacagc
    17341 gatttccaaa actttcttcc ttctaatagt ctacagtggg tagaccttgc gaaattcttc
    17401 taaaacaacc ttgctttcag gtgtaaaagt cagccctact tcacccaaac agtctgtgaa
    17461 aaagtcctca tgaacctggc gccaataggc aagtgatttg tctccctcac cttccttaaa
    17521 ggcatgttgc gcagaaactt gattgaagag ttcaacagaa acctttgtaa tttcgacaat
    17581 gcagacagac tgattttgac tatctaaaat gatatcgaag gtccctactt ggggaagtgg
    17641 ttcgtcttct agtacataga ggtcataggc tgatgctgtt gctgtctttt ctcctttaaa
    17701 caccaaatcc gctaaaagat ctggttcaac tccaaaagcc caagcatcga tttcatctcc
    17761 gatcaaagga ttgatttgct tgtatttatt ccacatttct tgcggtatca tgggtactcc
    17821 tttgtaattt tttactttct tcttttatgt gtttaagatg atctggatgg tcaatctcta
    17881 aatcaaaaat ctctggaata gaactgtagt ggataatgca cttgataccc aactgattca
    17941 ttttttgtat gaaagaagta ttcagatagc ctgctacagc aaaatcaatc ttgttctttc
    18001 ttgctttatc ctgcatatct cttagcatat ctaacattat tggactttcc atatcatgcc
    18061 attgactgtt tctcatagtc gcaaaaacaa aggaagtcaa atcattcatt ccaactacaa
    18121 tctttgaaat gcccgtttcc agtatactag ataagtcaaa atacgctgac ggtaattcaa
    18181 tcatcgttcc gactttccca gtaaaaccct gctgacgcaa tactgtaata gcttgtttta
    18241 attggtcggc atcattgaca aaaggaaaga taacagatag attggggttg gtttgataaa
    18301 cttctgtaac gacatgtgct tcagcctgaa attcatccaa acacgccagt aaacgcctgg
    18361 ttcctctata gccaaacaag ggatgccctt cgtcaaaaaa ctctctagtc cccactaaac
    18421 aattggcttc tgtattcgtt aattcagaaa aacgatacca aacttcttca tctgagtaca
    18481 gggagcagat agtctctaga taatctttta caaattgctg acaacttgct aatatgatgt
    18541 tttgattaag ctctctcaac aaatattccc cacgaatcat gccgacgtgg tgaaatagtt
    18601 gaggataaat tttttcaaga attttttcgc cactaagggc aagttgattt ctcatcattc
    18661 accttccaat tcatgtaaga agtcttgtcc agttctggaa atcctaataa ttcagactta
    18721 accttcaaga ctaatggcga tgcattttct tctgtaatct cttgaatatc catccaaata
    18781 tatccaagtg aatcattcgc accatcagac acagcttccg aagtcgtaac ttgaggtgca
    18841 ctctcattca tttcaacatc atacaaggcc atgacatggt gaaccataaa atttgttaac
    18901 tcttctctga cgaaaacatc gtagattcga ggattagagt agcttataac agtaaatccc
    18961 gtctcttcca taacttctct agtcagcgtt tccgtcagtc cttcaccaag ttgctgactg
    19021 cctccaggta gatcataccg atgttgataa gggcctctcg ctttttcaat gcagagtaac
    19081 ttcccatttt ctaagcaaac agcgtagact ccaaagtgtt ttttgatttc catccaactc
    19141 ctcctacttc aaagaccagc caccatctat tgtcaagatt tgtccttgca tggcgctcgc
    19201 ttttccactt gctaaaaaaa gactaagctc tgctatttcc tctggctcaa tccagcgctt
    19261 gattggggtt tcactagcca cccagtcagc caaaccacct ggttcaaaat ccgcagcggt
    19321 catagctgtc ttgactgctc ctggagcgat accaaagacc tgaatcccag cttcagcata
    19381 gtctagagcc aactgcttgg tgaagccagc caaggcatgc ttggatgaag tataggcgtg
    19441 accacctcca cctgctaggc tagaagcaat ggaacacata ttgatgatga ttcccttttt
    19501 attttccagc atttgtgtca aataataccg agtcaactct actggaataa tgtagttgat
    19561 ttcaaaaatc tcttgaatgt cctgcgccgt ttgttccaac agtggtttgt aatcatccaa
    19621 aactccggca gtattacaca aaacatccac ctgagggcac cagtcaaaaa taggttccaa
    19681 gtccaaggtc aaatctctct gtaaaaagtg aaaatcaccc tctaagagtg gcttttcacc
    19741 ttggtcaact ccataaactt gatagccctt ctctaaaaag aggcgagctt gagccaatcc
    19801 gatccctgaa ctcactcctg taatgagtac acgtttagtc atgcacttct acccaatccg
    19861 ttgccaaaac atcacaagct gtcgggctcc acatggaaaa accttctcct tctccagaca
    19921 cgttgattag gaaataaggt gtcatttcaa gtgcaagccc attttgctcg atggtatcaa
    19981 agagttggac atagttttca gcacctcccc aaccagttcg tacatatttt ttcttagcct
    20041 ttaagccagg tagaatttct tcaaatgtca tgtttttctc ctttaatgtc aataattctc
    20101 cccttcatta taacaaaaaa accgctttaa aacggctttt tgactgtgat ttatttacat
    20161 cttcttctac ttacggcaaa ttattccctg cagcaagata aatttcatac cattcttttc
    20221 ttgttaagct aaagtttgcc gcttggctaa cttctctcaa gtgcttagga tttgtggtac
    20281 ctacaactgc ctgcattttt gctggataac gcaatatcca agaaatggca atagttgaag
    20341 aggttactcc atatttaata gctaaacgat caagtacttg atttaaagct tgaaatttct
    20401 catttccaac aaaattccct ttaaaatacc cgaattgtaa gacagaccat gcttgaatga
    20461 ccacatcgtg taatttgcaa tattcaaaaa tgctgccatc tcgcatagct gcttgactat
    20521 cttccatatt aacatgaaaa gctgattcaa atcctggagt aaaagccgca ctcaattgta
    20581 gctgattaac agctaacggc tgcttgacat cttttttaag caactccatc atcataggat
    20641 tttgattaga aactccaaaa tctcgaactt taccttgttt ataaaggaga tcaaaggctt
    20701 ctgctacttg gtcagattcc atcaaagcat ctggtcgatg aaggagcaag ctatctagat
    20761 gatcaatctt caatctttgc aaaataccgt ctactgattt tataatatag tccttagaaa
    20821 aatcaaaata ggtaaattct tcaatgcgaa tgccacattt ggactgaatc cacatctttt
    20881 ctcttaaatc tggacgattt tttaggacaa gacctaacag ttcttcacaa cgaccacgac
    20941 cataaatatc agccaagtcg aaggcattga ttccaacaga aagtgctgtt tctacaagct
    21001 cttcaacttc ttttacagac ttatctttta ttctcatcat tccgagaaca atttctgata
    21061 attctttgtc atcttgacca agagttatgt atctcatcaa atttttctcc tttaatttct
    21121 aacattcttc ccttcattat aacaaaaaac cgctttgcaa cggctttttg actatacttc
    21181 actccatttt atcttcttaa acccacggaa caagacaaag attccaataa agaggacagc
    21241 taaaggaata acttttgtaa ggaaaacatt tgaaattccc atccactcat aataacggag
    21301 cagagaaccc accacaagat gggcaataat catactgaca aatggacgaa agaccgcttc
    21361 tttccaattc caaataccga taactagcga aatcgtaaag acagacaaac tatcccaggg
    21421 agccggaata taaaaggctc cttcttgtac aaaacttcct attcctacat atcccataac
    21481 aactagcaga acaagaatcc caacgacaat ataggtgcca attttcattt taggagaatc
    21541 ttggactaag caccaacgta agattgtggc cacaagtcca aatccaatca gaaaaataag
    21601 aagttgccct aaaaatgtga gcaaattgac tgttaagaga ggacctttag aaaaatcact
    21661 tagtagttga taataacgta ataccgctag gataagaatt ggcgtcaaaa gggactcttt
    21721 gatagaactg cgaggtgctc ccttgagaat ctctttcatt atttttttag gattcttacc
    21781 tagataatcc tctgcactca tgccatctcg ttctgcttct gagaaatcta gcatcatcaa
    21841 atagatctgc tctctgagat agtcttcatc atagagaaat ccagcaagat taaaactttc
    21901 ccacaactcc tcaaaatact tttgattctc ctcagaaaac tcatgtagca aagcgcttgt
    21961 ttcttcgtaa tacttcattt tcttcatggt ttaaccccca ttcttaatcc cttctacttt
    22021 ttgactcaaa tcgtcccatt gttgccaaaa gactgagaca cgctcttctc cttctttcat
    22081 taatgaaaaa tacttccgat ctggaccatc tggcgacggg cgcatgtcgc ctcttatcca
    22141 ttgatttttt tctaactttt gcaacaaagg ataaatagtt cctggaacga tagtatcaaa
    22201 tccagcctct cgcaaagtct gaaccaactc ataaccatac cgctcttttt gaccaatcat
    22261 atccaagaca caaccttcaa gaacaccttt taatagctga gtttctttca tcacttctcc
    22321 cttctaatct attttgtaat acctactagt aacttcacct atagtatatc acttctacac
    22381 tagtttgtaa agcataatag ttaatactct tcgaaaatct cttcaaacca cgtcagcgtc
    22441 gccctaccgt atgtatggtt actgacttcg tcagtttcat ctacaacctc aaagcagtgc
    22501 tttgagctga cttcgtcagt ttcatctaca acctcaaaaa catgttttga gctgacttcg
    22561 tcagttctat ctacaacctc aaagcagtgc tttgagcaac ccgcggctag cttcctagtt
    22621 tgctctttga ttttcattga gtataaataa aaaaaaacag aactagtctg aactagtcct
    22681 atctactttt acccaatcac acttccattt ggtacagctg gatcaactgt gagaagggtt
    22741 aatttgccat catgttcagc tgagagaatc ataccctggc tgacatattt tttcatcatt
    22801 ttacgtggtt tgaggttagc aacgatttga actttcttgc cgaccaattc ttgttcattt
    22861 ggatagtatt ttgcaattcc tgaaagaatc tgacgatctt ctccatcacc agcatccaag
    22921 cggaattgaa gcaacttatc tgaagcttct actttagaca cttctttgac ttctgcgaca
    22981 cggatttcga ccttatcaaa gtcttcaaac ttgatttcat ccttgtttag tttgagttcg
    23041 acttcgtctg gattccattc tttttcgaca gctggcttgt tgccttccat ttgttccttg
    23101 atataggcga tttcttcttc catatccaga cgtgggaaga ttggcgttcc tttggcaaca
    23161 acagtcacat ctgctgggaa gtcagccaag ctcaagttct caagactcgc tacttcatcc
    23221 aaaccaagtt gagtcaagac tgcacgactg gtttccatca taaatggttc aatcaagtga
    23281 gcaacgacac gaaggctggc tgccaagtgg ctcataacac ttgccaattg gtcacgaaga
    23341 gcttcatcct tggccaaaac ccatggtgcg gtctcatcga tgtatttatt ggtacgagag
    23401 ataagggtcc aaaccgcttc aagcgcacgt gggtagtcaa ctgcttccat gtgtgtatgg
    23461 tagtctgcga ttgattgttc tgcaacctca gcaagagcat tgtcaaattc agtcacacct
    23521 tctacatagg caggaatttg tccatcaaag tatttgttaa tcatagaaac cgtacggttg
    23581 aggaggtttc caaggtcatt ggctaattca tagttaatac ggcctacata gtcttctgga
    23641 gtgaaggttc cgtctgaacc aactggaagg ctacgcatga ggtagtaacg aagtggatct
    23701 agtccataac gctctaccaa catctcaggg taaacgacat tcccttttga cttagacatt
    23761 tttccgtctt tcatgacaaa ccaaccatgg gcaatcaaac gatcaggtaa tttaacatcc
    23821 aacatcataa gaaggattgg ccagtagata gagtggaagc gaaggatgtc ttttcctacc
    23881 atatggaaga ctgttccatt ccagaacttg tcaaagttac catgttcgtc ttgaccgtag
    23941 ccaagagctg tcgcatagtt aagaagggca tcaatccaaa catagacaac gtgcttagga
    24001 tttgatggga ctgggacacc ccaggtaaag gttgtacgag aaactgccaa atcctctaaa
    24061 cctggctcga tgaagttgcg aagcatttca ttcagacgac catctggagt gataaattca
    24121 ggatgggact tgaaaaattc gaccaaacga tcttggtatt tgctaaggcg aaggaagtat
    24181 gattcttcag aaacccattc aacctcatga cctgatggag caataccacc agtcacattt
    24241 ccagcttcat cacggaaaac ttctgccagc tggctttctg taaagaattc ttcgtctgat
    24301 actgaatacc aaccagagta ttcacccaag tagatatcat cttgagcaag taagcgttca
    24361 aagacttgtg cgacaacttt ttcatggtag tcatcagttg tacggataaa tttatcgtat
    24421 gagatatcta gtaattgcca gagttcttta actccaaccg ccattccatc aacataggct
    24481 tgaggtgtaa taccagcttc ttccgctttc tgctggattt tctgaccatg ttcatcaaga
    24541 cctgtcagat aaaatacatc gtagcccatc aggcgtttgt aacgtgctag gacatcacat
    24601 gcgatagttg tgtaggcaga accgatatga agtttcccag atggatagta aatcggcgtt
    24661 gtaatataaa aatttttttc agacataatt tttcctttcc aggcaaatga aacctgtttt
    24721 tctaacactt cattatatca catttttaat gaatttcgat agggaaatcc atacaaaaac
    24781 aagatagacg agtgtccatc ttgttgatct cattcataac gaagggcttc aattggatca
    24841 agtttcgatg ccttgttggc tggcaagact ccaaaaatca taccaacact agccgaaact
    24901 gcaagactaa atagggcaac tgggattgat actccaactt ctataccttc tattaaacct
    24961 tgcagtaaca aacctgctaa ggcagttaaa ccacttgcaa ttgtcaagcc aattaagcca
    25021 cctaacaagg tcaaaatcat ggattcaatc aaaaactgaa ttaaaatatt ggcacgtgtt
    25081 gcgcccaaag ccttacgaag accaatctca cgagtgcgct ctgtcaccga aaccagcatg
    25141 atgttcatga caccagttcc tccaacaaag agagaaatcc ctgcgatgga actaataatc
    25201 gtcgtcataa aactaaacga ttgttgaatt tctgcaaata caacggactc atctgccacc
    25261 tggtattctc cctgttgtaa gcctgcaagc tctgtcattt ttcgtgccag ttctggaccc
    25321 agagttgggg ttaaactggt atcattcact cgaaagacaa tactagctat ttcatctata
    25381 ttaaaattcg cagcaagaga gatattggta gtaataggca agccaccaaa cccatatatt
    25441 tttgaccttt tagcctccgg actagtataa accccaatga cccggtaact aaatccattg
    25501 acttctacaa ccttgttaat agcctcttga ggagattcaa ataaactaat ggacaattcc
    25561 tcatctagca aaatgacact tgcaaactct ttgaaatctt gctctctcag actacgacct
    25621 gcaataattt cattcttaac agcgtccatg taagttctgt ttccacctgt caaattagca
    25681 ttctcaacct ttttatcttg ataggtcaag atggcattcg ttgaattggt tacatagtaa
    25741 ctatccactc ccttcagttt agctgcctct tggacccagg attcttgcgg ttttggcggt
    25801 tcaacaggaa cttcctcttc ctttccagaa accgtaaaag ctgattgttt ctgagtaaaa
    25861 gacccatctt tacttttttt aggagagaaa aagacgctaa tatttttctg agatttagtc
    25921 atatctttat tgacttgacg agatagggaa tcacccaaag ccataatcac aacaactgat
    25981 gaaacaccga taataatccc aatcatagta agcaaagaac gcatcttgtg agccatgata
    26041 gatgaaaagg caaatttcag attctgcatc ttagttttcc tcctttccta actgagcact
    26101 gtcagacgaa atgaccccat cccgaatgac aatctgacgt ttggcatagg cagcaatctc
    26161 aggctcatgc gttaccatga taatggtttt tccttcttta ttcaaatcaa ccaataattg
    26221 cataatttgg ttacctgttt tggtatccaa ggctcctgtc ggttcatccg ctaggataat
    26281 agaaggattg tttaccaagg cacgcgcaat ggctacacgt tgcttttgac caccagataa
    26341 ttctgaaggt aaatggtgac tacgttctgt caattcaacc ttgtctaaat attcctcagc
    26401 caacttgcga cgttttgaag acgaaactcc tgcgtaaatc aagggcaatt ctacattttg
    26461 cagagcattg agcttcgata gaagaaagaa ctgctgaaag acaaaaccga tttgttggtt
    26521 acggacctta gccagttgtt tttcaccaag cccagccact tcttgacctt caagataata
    26581 ttctccactg gttggtgtat ccaacatgcc aatcgtattc atcagagtgg acttaccaga
    26641 cccagatggt cccatgatgg ctacaaattc accctcattc acttctagat tgatattttt
    26701 gagaacctgc agttcttggt caccattacg gtagcttctg aagatatttt ttagactaat
    26761 tagttgcttc atcagccttc acctcttttc cttcttccaa ggaagatgtt ggattactga
    26821 tgaccttagc accattcgtt aaaccagaag tgatttcttg attttctgcg tcagcatttc
    26881 ccaatgaaac ctcaactttt ttagactttt gttgttcatc cacaatccag acataatttt
    26941 tactatcatc cattactaga ctgctaacag gaacaagaat agccttagtt ttgcttttaa
    27001 cctcaatgtt gacagaaaaa ccctgtttca aatcaccaac ctcgcctgtc acatcaatag
    27061 tataagggta tttagaacct gtattattcc cggctgctgg actagctgct tcaccattgt
    27121 ttttaggata gtcagaaata tagcttaatt tcccagtcca ttttttatca ggatacactt
    27181 tagaagtaaa gcttacttct tgacctacag aaaggttggc tagattgtac tcagacaatt
    27241 ctcccttgac ttgtaaattt tcattgctga caatatgaac cataacttgg ctcgcccctg
    27301 ttggagattt agaaacattg ctattgactt cgactacagt tccctctagg gtactgagaa
    27361 cagttgttgc atccaattga ctttgagcct tgcttaattg cgccgcagca tctgcacgcg
    27421 catcacgggc atcacccaat tgagcgtcaa tagaagcaac agaatttcca gccactggag
    27481 ttgggctttg caccgttgca tcttctcctc ctactggcgc tggtaactgt ggagccggag
    27541 ctgaagcggc ttcatttcgt gcttgattga gttcattgat atgacgatct gccctagcta
    27601 ctgctcgact agctgaatca taggccgcct gcgcttctga actactgtac ttgactaaag
    27661 cctgcccttc gctgacctta tcgcccacag aaacaaggat ttcatctaaa tcacccttac
    27721 tagcatcaaa ataaacatat tgttcatttt ttgctgttac tgtccctgac aataaaacag
    27781 aggatgccac gcttccttcc ttggcaacaa caagatgagt aggctcatct tttagagcag
    27841 tctgagaagg ttgtctaaag agtaaaatcc ccccggcacc caatacaact acactcgcag
    27901 caccgattgc tgcatacagt tgccactttt tagctttacc attctttttc ttcataatga
    27961 aactcctttt cttttttaca atactttgct attataccaa atttccttcc agcaaacaat
    28021 gcagttcaga tggaaataat ggcagttcag gattaaacaa tcgttcggaa ttttgctttt
    28081 ctattgtact agatacataa tacactatct tgacttattt ggcaagcttt tttgcaattt
    28141 tttgtgcgta gcagattttt gcaatcaaat caaaaaaaga ataaaatata actatcaaaa
    28201 aagacactct actatttaaa agattacaaa ggagttttca atgagagaat atgatatcat
    28261 tgctatcggt ggaggtagcg gaggaatcgc taccatgaac cgtgctggtg aacatggagc
    28321 caaagcagcc gttattgagg aaaagaaatt aggtggaacc tgtgtcaacg tcggttgtgt
    28381 tcctaaaaaa atcatgtggt acggggcgca aatcgctgag actttccatc aatttggaga
    28441 agactacggc tttaagacta ctgatcttaa ctttgacttt gcaaccctac gtcgcaatcg
    28501 tgaagcctac attgatcgcg ctcgttcttc ttatgatggt agttttaaac gcaacggtgt
    28561 agacttgatt gaaggtcatg ctgaatttgt agattctcat actgtaagcg taaatggtga
    28621 actgattcgt gctaaacata tcgtgattgc tacaggtgcc catccaagta ttcctaatat
    28681 tcctggtgct gagctaggtg gctcttctga tgatgtattt gcctgggaag aacttccaga
    28741 gtcagttgcc attctaggcg ctggttatat cgccgttgaa ttagctggcg tactccacac
    28801 ttttggtgtc aagacagatc tctttgttcg ccgcgatcgt cctttacgtg gttttgattc
    28861 ctacatcgtt gaaggtttgg tcaaggaaat ggaaagaata aacttgccac ttcatactca
    28921 caaagtccct gccaagttag aaaaaactgc taaaggcatt accattcatt tcgaggatgg
    28981 taccagtcac acagctagcc aagttatctg ggctacaggt cgccgtccaa acgttaaggg
    29041 cttgcaactt gaaaaagctg gagtgactct gaatgaacgt ggctttatcc aagtagatga
    29101 ataccaaaat actgttgttg agggaatcta tgctctaggt gatgtaacag gtgaaaaaga
    29161 actgactcca gttgcaatca aggctgggcg taccctatca gaacgtctct ttaacggaaa
    29221 aacaactgca aaaatggatt actcagctat tccaactgtt gtcttttcac accctgctat
    29281 cggaactgtt ggtttgacag aagaacaagc tattaaagaa tacggtcaag accaaatcaa
    29341 ggtttacaaa tcaagcttta cttctatgta ctctgcttgc actcgcaacc gtcaagaatc
    29401 ccgtttcaaa ttgatcacag ctggttcaga agaaaaagtt gtcggacttc acggaattgg
    29461 ctacggcgtt gatgaaatga ttcaaggatt tgctgttgct atcaaaatgg gagcaaccaa
    29521 ggctgacttt gatgcaactg tagcgattca cccaacttca tctgaagaat ttgtaaccat
    29581 gcgttaatcg aaacaaaaga agctgatata aatatgtctg cttctttttt aatgattttc
    29641 gaatcaacaa aaaaattatc caacttgact agtcacgaaa atcggctgtt acagtttttg
    29701 ttaccttgtt tttaaaaaat agttgacatc gactcctata tgagtataat agttactata
    29761 cattagaaaa gaggttaact attttgaaaa aagctcacgt ttatgctatc cctgctattg
    29821 gggctgctct cattgctgtt ttggcacaaa tcagtcttcc aattggacct gttcccttca
    29881 ctctgcaaaa ctttgcaatc ggcttgattg ctactgtctt tagaccgaga gaggctgtac
    29941 tttctgctgg actctatctt cttctaggtg ctatcggtct tcctgtcttt gcaggaggcg
    30001 gagctggttt tcaggcttta gttggcccta ctgcaggcta tctttggttt tatctcgttt
    30061 actctggact tacttcctct ctaaccaaca gcaagagtgg tgttgttaag atttttcttg
    30121 caaacctctt gggtgatgcc cttgtctttg tcggcgggat tctcagcttg catttcctag
    30181 ctggaatggc atttgaaaaa gctcttgttg tgggggttct tccctttatc attccagacc
    30241 ttggcaaact tctggctatt agttttatta gccgtcccct acttcaacgc cttaaaaatc
    30301 aggcttactt tactaactaa aaaaggatat cgagttatca tgactcaata tccttttttt
    30361 tattttgaaa acttatactc aatgaaaatc aaagagcaaa ctaggaagct agccgcaggc
    30421 tgctcaaaac actgttttga ggttgtggat gaaactgacg aagtcagtaa ccatacatac
    30481 ggcaaggcaa agctgatgcg gtttgaagag attttcgaag agtattagtt gcctttaaag
    30541 gcatccacca tcgtttgaaa ttcttcattt gagagagtaa tccctttgcc cattttagta
    30601 tggtctggac tccaagcacg aatatcaaac tttgcagggg caccattaaa gctcacacgg
    30661 ttaatttcct tggtccaacc tttttcgttt tcagaaagag tcaacaagtg ctcttcgatt
    30721 tcaaatgtaa attctgccat tttcttctcc ttttttagtt tcattagttt attcgtaaaa
    30781 tcttgtagat tttaggaaaa ttttatataa tattgatata gaagaaggga ggccaatatg
    30841 agacataaat tccagcaagt tctagataaa atacatgatt ttttaaatgg acatgaccaa
    30901 cctgaccaga ctgaaaccaa ctcccttaca gccactattg aagaggctat ccagaaacaa
    30961 accgctgttc accttatctt gtctgagaca agctttacag gtgatatcat caaatatgat
    31021 cagcaaggcc agcaaattat cgtgaaaaat tttgccaaaa atgtgagccg gattattcgt
    31081 ataagcgata ttcaacgcct gcgatttgtc ccctcaactg tccaaacagc ccaaaaaaat
    31141 agatttaaga aagagtgaga tgtagttgct tcatcccact cttttttctt agcgaatttg
    31201 ttcaaaatgt aaatgaactg cgatatgatc tccataacca cttctttcca agtcacgttg
    31261 taaacgatag gaaatgtagt gttctgcaat ggtaatgtaa cctgcgccca ataaacgatg
    31321 ttcaaccata gattgaatca tactgatagt cgcacgttcc accttggctt cttgtaaatc
    31381 caaaactacc ttcttagtga cttgagcaag attttgacgc aaatcatctg tcaaaacata
    31441 aacagtttgg gctgccttca agatggcttg gtaaatctta tctggattaa attcagcaat
    31501 ttcgccatta cgtttgatta cttgcatagg tttctccttt attctttgtt ttctttgatt
    31561 tctgccagca ttttttcttc ttctactgtc agttgataat gttcaagtaa atccggtctg
    31621 cgctcgtagg ttttctttaa actctcgtac aatcgccact gacgaatctt ttcatggtgg
    31681 ccactcatca atacatctgg cacgaccatg cctcgataat catagggacg tgtgtactga
    31741 ggatattcta aaagacctga agaaaaacta tcatcttggt ggctagactc cttgccaatc
    31801 acttctggaa tcaggcgaac tgtagcatca atcatggtca tagctgccaa ttctccacca
    31861 gtgaggacat agtcgcctag ggaaatctca tctgttacca aggtcttaat gcgctcatca
    31921 taaccctcat agtgcccaca gataaagatt agctcttcct cttgagccaa atcttcagca
    31981 taagcctgat caaactgctt tccagcagga tcaaggagaa taacgcgcgg atttttcttt
    32041 tcaatagcat caaaggaatc gaaaataggt tgtgctctga gcaacatgcc ctgaccgcct
    32101 ccgtagggat catcatctac atgacgggcc ttttcagcat tttctcgaaa attatgatac
    32161 tggatatcca agagcccttt ttctcgagcc tttccaacga ttgagtgctc cagtggagaa
    32221 aacatctctg gaaagagggt taaaatatca atcttcatcg tctaaccctt ctaagatttc
    32281 cacatcgacc cgtttatttg gaatatcaac attgagaacc actggtggga tataaggtaa
    32341 aagcaaatca cgtttgcctt ttcgtttgac cacccagaca tcattagcac ctggttgcag
    32401 gatttccttg atggttccaa ccaagctatc accctcatag acttccaaac cgataatctc
    32461 gtgatagtaa aattcaccat cgtctaggtc attcaaatct tcctcagcga ccttgagact
    32521 gtatcccttg tacttttcga tagtattgat atggtacata tctttgaatt taataatgtc
    32581 aaagttcttc tgtttacggt ggctagcgat ggtcactgtt tggacaaact gatctttttc
    32641 atcaaacaaa gccagctcag ctcctttttt aaaccgttct tctgcaaaat ccgtcacaga
    32701 caagactcgc atctcaccct gtaatccctg cgtattaacg attttcccaa cattaaagta
    32761 gttcatcttg tctcctgtaa tctccttttt tccatcttat tctgacaatt ctcgaataat
    32821 agccgcaatt ttttccgatt ctgaccattg taaataatgg tgattccctc ctaaaatgag
    32881 tttagtattg gaagtccaat attctgattc tctgtactct ttttctctat aagtctgaca
    32941 aaaaataaaa acagggacat gagattctat cgacaaattc tcaaaatctt cctcagtaat
    33001 ctctccagat atctgaaatt ctggatcttg attttccaac tctaagcctt tttcttgcat
    33061 taattcccag atttttttat tcgtttcagg actaaatgtt gcttgagtta agttcttaaa
    33121 ataaagttca ggaccacact cgtcaatcag cctcatctgc tcttccattt ttggataagg
    33181 attttctgaa aaatcagcaa acatgacttt tttagttgtc ggttcaattg ctactaaagt
    33241 ctgacgctta attggtttct cgagtaattt gcaagctaaa attccactcc aactatgtgc
    33301 acaaagtata tattcagaaa ttcctaattc ttcaagtact tcataaaccg catctgcaag
    33361 attatctaga ttttttccag cttggtcatg aatcggactc ctacctgtgt tcggaaaatc
    33421 aattgtcaaa taaccaattg taggaggagg tttttcaagt ataagtgaaa aattttcata
    33481 acttggtagc aaacctgctc cgtttagaca aactagcact ttcttttgct tttgataagt
    33541 aacagagagg ctaccaattt ctgtagatac ttcaaacctc ttcataaaga aatccactca
    33601 ttctatataa tgaattatta aaaatcatta tcctttattt tatcacgttc caaggatttt
    33661 ctcaagttgg aggaagggga caacatctct actttccctt caataatcct tccaaattat
    33721 gtttatgttg gtaattaacg gctgcggttt tgtctttctc aaagacagtc ttggtaaggt
    33781 caatatgatt aatagctacg attgcgacgg tgtagtaaat gatatcagcc agttctctgg
    33841 caagttcctc gttcgaatcc tatcccttct tttcgaccag agcgcctatt caaaacctcg
    33901 gctacttttc cgacttcctc cactaacttc ataaagagac cttcatcagt ccgagactgc
    33961 tgttaatgtt cgattaagta gtcttggaat tgcctaaacg ttcaatcttt tatagtatat
    34021 tgaaactaga atagtacacc tttacttcta aaatattgtt agaaatcgat ttgactgtcc
    34081 tgatcgattt gtcctgttct tgtttcattt tactatatct tctattccac acaaaaaagc
    34141 gaaacatccg tcccgccctt cttatttttc gtcaataacg attcttactt ttttgtattc
    34201 agttgggaca gagtagacaa tcgttcttat cgcagaaata gtgcgaccct tacgaccgat
    34261 tacacgaccc acatcgcttt gatcaagatt caagtgatat tccaaaaatt ctggtgtatc
    34321 ctcaatcttg atagttaagg catctggttg tgaaattaag ggtttcacaa tcgcaataat
    34381 gagattttca atcgtatcca tctgtcaacc tactttaaac ttattttgaa aatttagaat
    34441 cgtggaattt tttcaatacg ccttcttttg aaaggatgtt acgtactgtg tctgaaggtt
    34501 gagctccatt agccaaccat gcaagaacgc ggtcttcttt caaagttact tggttttcag
    34561 caacaagtgg gttgtaagtt ccaactgttt cgatgaaacg tccgtcacgt ggtgaacgtg
    34621 aatctgctac gttgatacgg tagaaaggtt ttttcttaga acccatacga gtcaaacgga
    34681 ttttaactgc catttttaaa gtctcatttc tttaattttt tatttcggtg aaatagctga
    34741 gctatttagc acatgttcta ttatagcaga tttctggcat gtgtcaagaa aaaaacttga
    34801 cagactataa atttcttaaa gtatttagaa atttgttaga ataggaaata aatgtttgaa
    34861 agatgctatc cgtgaatact attttagaaa aattttataa agaacaccaa gtcaaaccct
    34921 tcatatcgcc tgaacgagag ttggatactt ggcttctaag tcccaagccc gttcccaaga
    34981 gaaatatgga cttattagta gatgattcac tagcaggaga tatcatttta ctatggagaa
    35041 tccagtttgg tacttttacc actgaaacat gattttaaaa actcccattc gaatatgatt
    35101 caaaattcgc ttagaatcaa tgttttccca ctttttcaaa aaataaattt tcatctaatt
    35161 taaataactt tcaattaagt gtgaattttg cttaaaatca ttaaaaaaca ccccatggtg
    35221 tgaaccatga agtgttgtaa atgctgtgtt gtagctagtt cttagcgttt agagaactgg
    35281 ctagctttac gagctttctt aagatctggt ttccaaaata ctttgagtac acttatggta
    35341 ttgatgcccc taaacatcta aaaactctgg tagaaaaagg gtatgctctt gtcgaaactt
    35401 cttttgactc acttgaccat ctaaatacta ccatgaaaaa gaatatcctg aagaagaagg
    35461 gagttactgg actttctaaa atgaaatctt gcgacctgga tcaagccctt catgagcatt
    35521 tttcagaaga agaattagct ggtcactttc atgtccttct atggactttt ttacaatggc
    35581 attgctatca cacccaatac ctatctaagc gcctggttcg taaactttat tgcagctctt
    35641 cctctaaatt tcctaattgt tgaaccaatt gcccgtttta tactaagttc ttttcagaaa
    35701 ccatttactg gggaagaagt tgaagatttt caagatgatg atgaaatccc aactattatc
    35761 taagccagtt ctgtaaacta ctaatatttg aaatccactt ccttttaggg tacaatggtt
    35821 ataaatgaat ttttgagagg atcagaatga aaaaactagc aacccttctt ttactgtcta
    35881 ctgtagccct agctgggtgt agcagcgtcc aacgcagtct gcgtggtgat gattatgttg
    35941 attccagtct tgctgctgaa gaaagttcca aagtagctgc ccaatctgcc aaggagttaa
    36001 acgatgcttt aacaaacgaa aacgccaatt tcccacaact atctaaggaa gttgctgaag
    36061 atgaagccga agtgattctc cacacaagcc aaggtgatat tcgcattaaa ctcttcccta
    36121 aactcgctcc tctagcggtt gaaaatttcc tcactcacgc caaagaaggc tactataacg
    36181 gtattacctt ccaccgtgtc atcgatggct ttatggtcca aactggagat ccaaaagggg
    36241 acggtacagg tggtcagtcc atctggcatg acaaggataa gactaaagac aaaggaactg
    36301 gtttcaagaa cgagattact ccttatttgt ataacatccg tggtgctctt gctatggcta
    36361 atactggtca accaaacacc aatggcagcc agttcttcat caaccaaaac tctacagata
    36421 cctcttctaa actccctaca agcaagtatc cacagaaaat tatcgaagcc tacaaagaag
    36481 gtggaaaccc tagtctagat ggcaaacacc cagtctttgg tcaagtgatt gacggtatgg
    36541 atgttgtgga taagattgct aaggccgaaa aagatgaaaa agacaagcca actactgcta
    36601 tcacaatcga cagcatcgaa gtggtgaaag actacgattt taaatcttaa aaaccaaaaa
    36661 aatacagtat ccacattcgg tactgtattt cttttactct cattcttaag ttaaattatt
    36721 aaaatcccat atttggtcta tccagccttc ataaaagtct ggctcgtggc agaccataag
    36781 gatagatccc ctatattctt tgagagcgcg tttgagctca tcctttgcat ccacatccaa
    36841 atggttggtc ggctcgtcca gcactaaaac gttgttttca cgattcatca agagacagaa
    36901 acgaaccttg gcttgctctc cccctgataa tacttgaatc tggctttcaa tatgtttggt
    36961 tgtcaaacca caacgggcaa gggctgcacg gacttctgct tgattaaggg caggaaaggc
    37021 attccagaca gcttcaagag gagtttggcg attaccgcct tctacttcct gctcaaaata
    37081 accaagttct aaataatctc cacgctccac ttccccagcg attggcgaga taatgcccaa
    37141 gagactcttc aagagagttg tttttccaat accattagca ccaataatcg caaccttttg
    37201 attgcgttcg aaggtaagat ttaaaggctt agtaagagga cggtcgtaac caatttgcaa
    37261 gttcttggct tggaagataa agcgccctgg tgtacgagct ggtttgaaat caaaggatgg
    37321 ttttggtttc tcactttgga gttcgataat atccatctta tccaatttct tttgacgaga
    37381 catagccata ttacgagttg caacacgggc tttattacga gccacaaagt ccttgaggtc
    37441 tgcaatctct ttctgctggc gttcgtaggc tgcctctagc tgagatttct tcatagcata
    37501 aacttcttgg aactggtagt agtcaccaga gtaacgcgtc agctgttgat tttccacatg
    37561 atagacaata ttgataacgt cattgaggaa tggaatatcg tgcgaaatga gaacaaaggc
    37621 attctcatag ttttggagat agcgcttgag ccaatcaata tgctcagcat ccaagtagtt
    37681 ggtcggctcg tccaacagca aaatatcagg cttttcaagg agaagttttg ccaaaagcac
    37741 cttggttctt tgcccacctg acaaagaagt tacatccgta tccatgccaa agtccataac
    37801 accaagagca cgcgctactt cgtcaatctt agcatccaag gtatagaaat cacgactctc
    37861 cagacggtct tgaagttctc ctacttcttc catgagagca tcaacatccg cgccgtcttc
    37921 agccattttc atatagaggt cattgatacg agcttcagct ttgaaaagct catcaaaagc
    37981 cgtacggaga acatcacgca ccgactgtct ttcagcaagg acagagtgct gatccaagta
    38041 accagccgtc acatatttgg accactcaac ctttccttca tctggcagca ttttaccagt
    38101 cacgatactc ataaaggttg attttccttc accattggca ccgaccaggc cgatatgttc
    38161 tcccttgagg agacggaagg acacatcttc aaaaattgca cggtcaccaa aaccgtgact
    38221 cagattttta acttctaaaa tactcatttt aattccttat cttgttttta tgtaatcgtt
    38281 tataaaggag ccaagccaga tagccaccca aagtattggt ccacaaatca tcaatctcaa
    38341 agacgcgatt gaaatcaaag aaaaagtcca agattaattg cgtacactcg attccaagac
    38401 tcacaagaaa actaaaaaga aggacctttt ttgttttccg caaatttgga aatagataaa
    38461 ggagttggaa aatcagagga aaaaataaga agacattgag gacattttgt aaaaaaatcc
    38521 aacataattg tccaatgtca ctcacttcgc ccagtttcca gagagaattg aaaggagtca
    38581 aaagaaaaac caggcgtcca agatgctgaa tatctggagt tcccactccc acggtagatt
    38641 gttcttgagg agtaaagcaa aaacagacaa tgcaaatgct atagaaaatg actccccaga
    38701 ccaaaatatg attataagtc ttcttcatca ttaaggattt accgctgcga ctgccttctg
    38761 gcggtcacgt ttcattgtgt tagagcgcaa ttgtccacaa gctgcgtcaa tatctgtacc
    38821 atgctcttga cgaaccacac agttgacccc ttttttctta agcgtatcat agaaagccaa
    38881 cacgcgctct ttgggactac ggctatattg gtcatgctca ctaactgggt tataaggaat
    38941 caagtttaca taagacaatt tcttgatgtt cttgagcaat tcagccaatt ccaaggcttg
    39001 ttctacaccg tcgttgactt cattaagcat gatatattca aaggttacac gacggtttgt
    39061 tgtctcaatg tagtattcaa tagcagcaaa gagtttttca atcggaaagg cacggttaat
    39121 cttcatgata cttgaacgaa gttcattgtt gggtgcgtga agagacacgg caagattgac
    39181 ctgaacccct tcatcagcaa agtcacgaat tttatgagcc aaacctgaga ttgaaaccgt
    39241 gatgtgacga gcactgatag ccattccttt atcatcattg atagtacgaa agaaattcaa
    39301 gacattgttg taattatcaa agggctcacc gattcccatg acaacgatat ggctgacgcg
    39361 ttcatcctga ccacgctcag caaagtattt ctgaaccagc atgatttgcg ctacgatttc
    39421 accgttattg aggtcacgct gcttcttaat caaaccagag gcacagaagg tacaaccgat
    39481 attacagccg acctgagtgg tcacacagac agataaacca tagtgttgac gcatgagtac
    39541 agtctcaatt aacataccgt caggcaattc aaagagatat ttgactgtac catcagcaga
    39601 ctcttgcaca atacgttgtt tcaagggatt gaccacaaac tggtcattga gcttagcaat
    39661 caaatccttg gaaaggttgg tcatttcttc aaatgactgc acacgtttac ggtagagcca
    39721 ttcccagatt tgatctgcac ggaatttctt ttctccctgc tccaataccc attcctgcat
    39781 ggtttgatgt accaaactat gaattgaggg tttcatttct tctccttatt ctctactcac
    39841 ttctgacgaa tgacaaaatg acgttgttcc ttgtcctctt tctgagaatg ctggtctttc
    39901 tgacgacgtc tatttttctt atctgcattc gactttcgtt tagtttgagt cggtttcttt
    39961 ccttttctag aaggtgtttc ttcttccgtc ttacgcattt tcttgtcaaa tgatgctcgc
    40021 ttaggggctt cattttctaa gacaaaatag gcacaaccat aactacaata ctctaaaagg
    40081 tagtcttgta aacgactgat tttttcaagt ttttcttctg ttcggtcatc cttgtaaaaa
    40141 cctcgtaggc gaagctgttc gttgctccag tcccccacga tataatcaaa cttggttaag
    40201 acttctgaaa aacgctgatt aaaagtcgtc acatcaaagg catccttgat attttcaacc
    40261 aaggaaaaag ctatcccttc cgtttcgacc ttgtccccgt gtaaatggaa ctccggacca
    40321 ggaaacttgt tatagttgta taattcaggt gcaatttctt ttcgcataga tatccttttt
    40381 ccacgattac ttaatacttt attctaccat aatttctagc agttagcacg tttctcataa
    40441 aaaatgaaaa aagtctaacg attttgtcag accagaatct tataacctaa aaaagagaag
    40501 aacaattctt ccctccaact atcattattt agcagctgcg tacaattcat ctactttatt
    40561 ccagttgatt actgaaaaga aagctttgat gtagtcagga cgcacgttgc ggtatttcac
    40621 gtagtaagca tgttcccaaa cgtccaagcc caagattggt tttttacctt ctgagattgg
    40681 tgtgtcttgg tttgctgttg aagtcacttc aagtttccct tctttgttga caaccaacca
    40741 tgcccaacct gaaccaaaac gagttgttgc tgctgcagtg aaggctgctt ggaattcttc
    40801 aaatgaacca aatgttgcat cgattgctgc tgccagttct gctgaaggag ctgttttctc
    40861 gggagtcatc aattcccaga aaagagcgtg gttcaagtgt ccgccaccat tgttgataag
    40921 tgcttgacgg atatcagctg ggatagattc tacatcagca agcaaggctt caaggtcttc
    40981 accgatttca gggtgttttt ctaaagctgc attggcattg ttgacataag tttgatggtg
    41041 tttgtcatgg tgcaaatgca ttgtttccgc atcgatgtat ggttccaaag cgtcgtatgc
    41101 atatggaagt tctggtaaga taatagccat ctgtaatacc tctttttctt tctatatgaa
    41161 aatgataacg caaacattca cttttttcaa gttttttgct tatagataag caaatcagca
    41221 agaaacccac gacaagataa tcctgacgcg ggttgtagtt tcaacaaatg tcaattgacc
    41281 tgactagcaa tctgtaagag tgccttttca aaaaggaaac ctttttcata aagacctgtc
    41341 ttaatctgat agtctgtctc aatcaaatag gaaatagctt gcttcagaaa gctcaaagaa
    41401 agtcctctcg aatctcttaa tgcaaacttg atttgataag gatttgggtt acgtcccaga
    41461 taactaccta aactacttgc aatctgcgat tctgtttggc cagactccgc caaaatcttc
    41521 acctgagtaa aagtccgaaa ttgtcccagc atgactgcaa ttagtttgat ttcatcttcc
    41581 ccttgcaagg tcaagtctct caccaaatcg cgcgcctgat ccatcttttt agtcagaata
    41641 aactgagtta aatcaaaaat attgtcctgc aaggtcttgg gaattgcgtt aacaatatcc
    41701 tcttcctcga taacagaatc cgccttatag gactgtaaaa agagaagatt tttctggatt
    41761 tcgctaaatt gaaaccccga cttgatgagg agattttcaa aagaatgatt ggtaaactgc
    41821 agaccttgtt tctgactcca cttttggaaa tactggcgca attcttgttc ttttacttct
    41881 actgcatcga aggccttggc atcacgctta agtaatttga ctaaccgtct tttgctatcc
    41941 agctttcctt ctgcaaagat tatcaacttg gttgttggag aaggattgtc aaggtattcc
    42001 tcaaatgact taagctcatc atctgtcaaa aagcgtttct tagcagtcgt gatatccata
    42061 aaataatcta atatcacgat tttctcatcc gcaaagaaag gaaggctgac caactccagt
    42121 tccacatcct tgtaaactac ttctttcata tcaaagtagg caaagttgag gtcagcagaa
    42181 tcatacccaa tctgtttcaa cacttgactc ttcatcactt caaactgacc ctgatctgtc
    42241 cctgtaaata ggctcaggct cggtaaattt gataaagtca acttctgact ttcttcaatg
    42301 gctagcatcg tctctccttt cttcagattt ttcgatttaa tttagtcaat atagcgcaat
    42361 ttcccacgga aatcttctaa gctctcgtag cctttttcca ccatgattgc tttcagttca
    42421 ttggtaatgc ggtcaaaagc actgacgcct tctttgtgaa gggtcgttcc cacctgcacc
    42481 atacttgctc cacagaggat gtgttcaaag gcatctcgac cagtcagaac gccacctgtt
    42541 ccgataattt ggatttgagg atttaaacgt tgataaaagg cgtgaacatt ggctagagca
    42601 gtcggtttga tgtattctcc accaattcca ccaaaaccat tcttaggccg aataacgaca
    42661 gattcgtctt ctatatagag gccgtttccg atagagttaa cgcagttgac aaacttgagc
    42721 ggatatttgt tgaaaatagc tgccgcttga tcaaagtgaa caatatcaaa ataaggtggc
    42781 aatttaattc caagaggttt ggtgaagtaa gcaaacactt ctgccaaaat ccggtctgtt
    42841 gtctcaaaat cataggcaat ctgaggttta cctggaacat ttggacagga aagatttagc
    42901 tcagtcagac cacgaaaatc actctcttga acttttttca aaatagtatg ggtttcctct
    42961 ggagacatgc cgaccagaga taagaagaaa gttcggttcg actctttttc ctgcaaatct
    43021 aaaagataat ccaaataata gtctaagcca ttatttggca agcccataga gttgatggaa
    43081 ccaagtggaa catcttggta gcgtggctca ggattcccct gacggaagtc caaggtcgct
    43141 gtcttagtaa caaaggttcc tgccgctgag tttttgacct cttctaactc ctctatcgtc
    43201 atacaagcca cacctgctgc attcatcaag caattgtcaa actcaaaacc agcaatttgt
    43261 gttttcgttg ataccatgat tctaatcctc cagatttctt ttattgctaa tattatacca
    43321 taattttaat tctaggttta ctagattctg tggttctatc tatttattcg gaaaagaaag
    43381 tctagtacag aagtcatgct atgaaaacag ctagtgtatt ggaagtttga acaaggcttg
    43441 ggtaacagac ttttgaatga agtccaagca acaaggagaa atctcaacca tgagtccatt
    43501 ccatgactct gttgctctag aaaaccttgc aatagtcaag tgataacgaa taaaactttg
    43561 gattgaaata tccccatgat tatctattac gaggagaaat ctcaaccttt atcattttta
    43621 aagaaatata gtaaaatgaa acaagaacag gagaaatcga tcaggacagt caaatcgatt
    43681 tctaacaatg ttttagaagt tgaggtgtac tattctagtt tcaatctact atacatgtaa
    43741 atctctactt tcgcaaaatg gattttcaga acagtatccc agtatagtta aaaactataa
    43801 aaaagagagg acgttcccct cttaaaatct tattttactg cttctttcaa agcatctacc
    43861 ttatccaaac gttcccatgg aagatcaata tctgtacgtc ccatgtgacc gtaagccgat
    43921 gtttgacggt aaattggacg cttgaggtcc agcatttgga taatccctgc agggcgaagg
    43981 tcaaagattt gacgagccgc tttttcaagt tgactttcag ctactgttcc tgtaccgaaa
    44041 gtatcgatac gaacagaaac aggttgcgca acaccgatag cataggccaa ctgcacttct
    44101 gccttcttag caaggcctgc tgcaacgata ttcttggcaa tatagcgagc cgcataagag
    44161 gctgaacgat ccaccttagt cgcatcttta ccagagaagg caccaccacc atgacgagag
    44221 tagccaccat aagtatctac aataatctta cgaccagtca aacctgagtc cccttgagga
    44281 ccaccgatta caaaacgacc tgtcggattg ataaagaatt ttgtcttatc atcaagataa
    44341 gaagatggaa taacttcttt gatgaccttg tcaatcacat cttgatggat ttgttcatta
    44401 gtggcctctg gatcatgctg agtagaaata acgactgtat ctacacgtac cggacggtca
    44461 ttttcatcgt actcaactgt aacttgtgat tttgcatctg gacggagata gctaatttct
    44521 ccagacttac gaagttctgc cagacgacga accaatttat gactgagtgc aattggcaat
    44581 ggcatgagct cttctgtttc atctactgca aatccaaaca tgagcccttg gtcacctgct
    44641 ccaatcaagt ccagtggatc ttgatcagca tttccacgaa cctccaaggc ttcgttaaca
    44701 ccttgagcga tgtcaggaga ttgttccacc aaagatgggt gtactcccac cgtctcagca
    44761 gaaaatccat attctgtatt ggtataacca atctctgcaa tggtatcacg aaccacacgg
    44821 ttaatatcca cataggcatt tgtagaaatt tcaccaaaaa cgtggacaga accagtatat
    44881 acagctgttt cagcagcaac gtgcgcctct ggatcctttg ctaaaatagc atccaaaatc
    44941 gcatctgaaa tttggtctgc aatcttatcc ggatgcccct cagatacaga ttcagacgtg
    45001 aataatttac gttctgacat aaaaatgtcc ccccttaaaa aatattgtta tagagttaca
    45061 aagtactgat aggaaaactc ttcgtaataa atacctatca tcttatcggg actatataac
    45121 tttatcatta taccattttt aatcgcaatt tgcagtcttt aatgtagtgt ttcggtttag
    45181 atagttcgtt ctcataaata aaaaagttgg agctcagtac tccaacaatt tctattaaaa
    45241 tgtttgacgt ttagctttac gctctgcacg accgcgagcg cgattttcag cacgcttggt
    45301 tttacggcgc ttttcatcaa ccgcccattg aattttcttc ttataacccg gtttgacttt
    45361 tttctttttc tttttaacca aaccaatcat ttcgatatca agtttatctt gttttttctc
    45421 acggttggca cgacgatcac ggtcataggt atcttgaaat tccccgtctt tgaccatctt
    45481 aggactaaac ttgattccca atttctccaa ctcacggata tccgagtcat cacttggctg
    45541 ataaagggta atagctgtac ctggtaggcc atttcgtcca gtacgaccaa cacggtgaac
    45601 aaaaaaagat aagtcttgcg gaatggcatc attgatgaca tggctgacac cttcaatgtc
    45661 aatcccacgc gctgctaaat ctgttgcgac aatatactca aaatccagat tttgcacctg
    45721 attcatgatt cgcttgcgtt cacgaggggc aatatcgcca tggatttttg caaccttcaa
    45781 accttgagaa gtcagatatg aatgcaattc atcagcacgc gttttagtgt taacaaaaat
    45841 cattgccaaa tacggctgca tcaactgagt caactggtaa atttgagcat tcttatcatg
    45901 tcccttggtc gaaatcaacc aattatcaat ggtgtcagaa ataaccgttt tggtcttaat
    45961 tttctccata acaggattgg ataagtattt tttcaagaat ggttgcagtt tttgtgggat
    46021 agtcgctgag aagaccatga attgcaagtc ttttggaaga ctgccagcaa tcttatcaac
    46081 agtttccaag aatcccatat ccaaggtcat atctgcttca tcaacaacaa atgtcttggc
    46141 tttatgaata gctaaatcac cagatttaac caagtcgtag atacggcctg gtgttccaat
    46201 aacaatatga ggctgattgc ttgccaattt ctcaatctgg cgagccttat ccgtaccacc
    46261 cacataatta accacacgaa cttcgacatc tgagtgagct gaaatctgac gcgctacttg
    46321 gtaaatttga gtagccaact cacgactcgg tgcagtaatc actgcttgta cactatcgct
    46381 agcttcatct aattgctgga aaatcggtaa caagaaagta tgagtcttac ctgaacctgt
    46441 ttttgattct cctactaggt cacgacctgc caaaacaata ggaatcaact tgtcttgcac
    46501 ctctgttgga gttgtaaatt ttaactcctt caaggcttct ctaatatagt ttttaaattg
    46561 aaatttcgta aatgacataa catcctcgat tctatctatc ttatcaatta taccatattt
    46621 tattccatta cagtagtctc acttatttag gctatttcca gtagcttctc tagtaagaaa
    46681 aggctggaat tttatagttc caacctcttt tcagttatta tttccagttt aatatagcat
    46741 tcaagccata gtgatcactc acttgtggac tcttgttacc atcaaatacg acatgtaaat
    46801 tttccaccgc taactctttg gtagtaaaga cataatcgat tcgaaggggt tcagtgttcc
    46861 ctttccagcc atcaatttca ggcggaacag tatagctacc acttttctct tgagcaactt
    46921 caaatgcgtc ttgtaagcct aatggactag ctaaaatagc ttggtaacct tcctgtccag
    46981 ccggattgtt gaaatctcca gctagtaaaa gtggcttgtt caattttttc aagacagcct
    47041 caaatcgtgc ccattcttct tggaaacctt tatcccacca agagagatga acactggcaa
    47101 ctgctagctc cttgccatcg actacagttt cagctagggc aacacggcga gtatgatagt
    47161 ctgttggatc atccacatct gaaaccaaaa tttctctggt ttcaataggt gttttagaca
    47221 agatagccac accttcgtgg tagcggttat agccgatatg gttataggcc caggtccagt
    47281 agtaattttt cccttgctca gacaactttt caaccaagag tctaacataa tggtcttggt
    47341 gaataggctc agctgctggc aaagcttgat aaaggtcatt aacctccacc tctgacgagg
    47401 tcatctcctg attgatttct tgaaaacaaa tcaaatcata gtccttttca agaatatctt
    47461 caagcaaaat ctggaatttt tcctctgctt ctttctccat ccaactgtga gtattgagtg
    47521 ttaaaaattt cattcttttc tcccaaaata agaggttgga atacagcttc caacctcaag
    47581 tatattacaa ttctacttta gcaactgctg ttttagctgc aagagaacct gttttttcta
    47641 atttaactga tttaattgca tcaccatttg tgaagacaac tactgttgaa gtttcacgtc
    47701 ctgctgcacg gatagcatcc aagtcagctg tgacaaggag atctcctgct gtaacttttt
    47761 gtccttcagc aacatgaact gtaaatggtt taccttcaag acttactgtg tccaaaccaa
    47821 tgtgaaccaa tacttcaaga cctgcttccg tcacaatacc aaaagcatgt tttgttggga
    47881 agatgcttga tacagtacct gaaactggag atacaatgtt tccatttgca ggttctactg
    47941 caaatccatc acccatcatt ttttgagcaa atactggatc ctttacttgt tccaaagcaa
    48001 caacttgacc gtctgctact gagtaaactt cctcagtaag atctttgaag tgaacagtgt
    48061 tttgttgtgc ttcagtcatt tggcttggaa gagtttcagg aatgatttca cctgaatcaa
    48121 ggatatcttg gatatcagat ttcaaaatgt cagcttttgg accgtagata gcttgaaccc
    48181 cttgtccttt catgacaaga cccatagctc cttctgcttt ccattgctct gcatttccta
    48241 ctttatctgc atctttaaca gttacacgaa gacgagtcat acatgcgtca acatcaacga
    48301 tgtttacacg tccaccaaga aggttgataa tgtttacagc ttgagagcct gctgcaactt
    48361 tcacttcgct gctggtttct tctgaacctt cagcagtttc gtagtttccg ttgcgccctg
    48421 gagttgcgta gttgaatttt tgaatcatga agtttgcgat aaagtacatg attacagcaa
    48481 agagaacagt tacccaaacg aagttaacga tatccatacc aataccagca ctgattgcaa
    48541 taggtgtacg agtcaagaac tcgattgaac cgaatgagtg catacgtagg tttacgacgt
    48601 cagccatagc gaaggcagca ccttgaacaa gtgagtaaac aagatacata ggtgttgcga
    48661 tgaacatgaa catgtattcg attggttcag taacccctgt caagaatgtt gcaagagctg
    48721 ttgcaatcat catacctttg tatttatgtt tcttgtcagc atcaacatta cggtagatag
    48781 caacaatcac acccatcaag ataccgaatg aaccgatcat ttgtccaact ttgaaacgag
    48841 ctggatgtac tgtatctaac aagtgttgat attgactagc atcagtacct ttaaggttta
    48901 caaggtctgt tacccatgca agccatagtg ggtcttgacc gaatacttga gtacctttag
    48961 ctgcaccagt taaaatgtca taagtaccac caagagctgt gtagttcatt gggatagtca
    49021 acatgtggtg aagaccaaat ggcaagagca aacgttccaa agtaccatac aagaatggtg
    49081 caagaattgg agcagtttct tgtgagttgg caatccagat accgaagtta ttgatacctg
    49141 tttgaactac tggccagaaa gcagcaagta gaattgcagc gattgctgaa cgaagaataa
    49201 ctacaaatgg tacgaaacgt ttcccgttga agaatgaaag tgcatcagga agtttacgga
    49261 agttgtagta tttgttgtaa gcagttgccc ctacaaaacc tgagataatc cctacgaata
    49321 cccccatgtt caaggctgga gcttcaagaa cactgataaa gtaatcagca actttgattg
    49381 aaccaccaaa gaaagtagtt accatagcat ctggattttt caacatatcg cctgatacac
    49441 caaagattgt accagtgata cggttaatca agatgaaggc aagaccagcg gcgaaagcac
    49501 caccagcacg ttctttagcc cagcttcctc caatggctag ggcaaacaaa atgtgaaggt
    49561 taccgataac cccccaaccg atttgctcaa gaattccacc tgtgatgaca agtggtgcaa
    49621 aggttgggtt aatcatcacg atagacttac cgattgaaat catcaaacca gcagccggca
    49681 taaccgcgat aactaccatc aaagccttac cgaatttttg ccaaaattcg aaagacaaga
    49741 catttttgaa tgtatctttc atcattcaaa tctcctttat ttttatttag gcaaacgttt
    49801 tacgaaaacg tttgcacttt ctatgattta attataccac tttaattttt tttgtaaagg
    49861 cttttataaa aaaattacac ttttttctaa aaaatttcta gtgcgccaaa tttcaagttc
    49921 aaattagcca tcaagaagtc ttctctgggg gacttctttg gaagctcttt tcttctgcgc
    49981 atctcttttc aaaaactctt gtagcaaaaa aggagatttt acaatctcct cataaaagca
    50041 gctattttac ctaaatcttc aagaatcggc gcatggatat tcctgatccc aatgaaccaa
    50101 tgaaaacccc aatcacaaat agtagggcaa tcatcaacgg actaaataaa tctggactaa
    50161 tcatggatag attttgccct accaacgatt tgttgacaga ttggtaaaca atttgataaa
    50221 caataaagac caaaacagat ggtgcgatag ctcccaataa accgataaag gctccttcta
    50281 acaagaacgg tccacggata taactgtttt tagctccgac caagcgcatg atttgaattt
    50341 cgcgactgcg ggaaataatg gtaatacgaa tggtatttga aatcaagaaa actgcgataa
    50401 aaattaacaa agcagcaatc cctagtcccc aaacacggat aaatgaagct aacttgaaga
    50461 gtctttctgt attggcaccg ccatcttgaa cctcagagac accttcaatt tttttagcat
    50521 cttcggctat agtttttaca tcatttggag tgtttgcctc tacaatatag gcatcataga
    50581 gaggattggc atctccttca aagattttcc agttatctcc cattatctcg gttaattttt
    50641 catattgttc ttctttactt gaaaaggtaa cacttttaac cgtagacatg ttcttcaaag
    50701 aatcatatac cttgtggtag tcattatttg taacagtttg accttctttt tcaattgtct
    50761 gactattatc ttccacatcc tttcggatat aaactactac acggacatta ttttcaatat
    50821 ctgtagctag tttcgctgta ttgaaaataa cagatgcaaa tattgccacc aaggtcaaag
    50881 taatcatgac tgaactgaca gcagctactg tcatccaacc atttcgtttc aaacttttta
    50941 aggcttcaaa taaatggcga aaaaatctac taatcatcgt atccatactc tccttttgat
    51001 tcgtcacgaa cgacacggcc attttcaatg gcaatgacac ggtggcgcaa ggtatttaca
    51061 atctggctat tatgagtcgc catcaaaata gttgttcctt gtaggttaat ccgttccaag
    51121 agattcataa tttcccatga attatccgga tccagatttc ctgttggctc atcagctatc
    51181 aatactttgg gattatttac aattgcacgc gcaatcgcaa tccgctgttg ctccccacct
    51241 gagagttcat ttgggaaaga acgaacctta tgcttcaatc caaccaagtc caaaacttcc
    51301 atcactcgtc ttttgatatt acggcgattt tccccgatta cttccatagc gtaagcaata
    51361 ttttcataga cagttttctt tggtaacagt ttataatcct ggaagacaac cccaacacta
    51421 cgacgtagaa gcgggacatc tttctttttg atcttaacca gattaaaacc agcaactgat
    51481 agacttcctt tatcgatttt tacttcacga tacagagaac gaataaaagt tgacttccct
    51541 gctcctgaag gtcctacgat gtaagcaaat tcccccggtt gaacgctaac cgaaacaccg
    51601 cgtagagcag tcgttccgtt gtcgtatttt ttaacgacat ctctcatttc aataattgac
    51661 atgtgagttc ctttctatct tagctaattc gccacttgag ataagcatcg ataaaaccat
    51721 ctaggtcccc atccataacc ttatctacct gagcaacctc atagctagtt cggtgatctt
    51781 ttaccatagt ataaggcgtg aagacataag aacggatttg acttccccaa gtgatctcct
    51841 ttttctcacc tttgagagaa tctacctccg cagccttctt ctcttgctcc atttgataga
    51901 gcttagcctg caacatcttc atggcgcgat ctctatttcc atactgggta cgatccactg
    51961 ttgattggac aacaattcca gttggaatgt gggttaaacg tacacctgtt gaaaccttat
    52021 tgacgttttg tccaccggca ccacctgaac ggaaggtatc catcttgata tcatcttcac
    52081 ggatttccac ttcaatagta tcatccaatt ctggcatcac ttctacagat gtgaaagagg
    52141 tatggcgacg tttggcagag tcaaatggtg agattcgcac taagcgatga acacccattt
    52201 ctgacttgag gagaccatag gcattaggcc cttcaaatga taaagttacc gacttaatac
    52261 cagcctcatc acctgcttgg taatccaaca cttccacttt aaagccttta gcattaccat
    52321 aacgagtata catacgaagc aacatatcac cccagtcctg cgcctcagta ccaccagaac
    52381 ctggatggat ttccaagatg gcattgttgt ggtcataagg ttctgacaag agtagagtca
    52441 tctcgtagct ggtcattatc ttatcaagtt cggctaactg cgctaccagt tcatcatgca
    52501 ctgactcgtc ttcagccaaa aaatccaata aaatttcgac ttcatcctgc aactcttcca
    52561 tcttatggaa ggtattgtaa gtgtttttta attcattcaa ttcttgcgac gttttttggg
    52621 ccgcaatatt atcgttccaa aaatcaggtt ctgtcatctt gttttccaag atggcaatct
    52681 cttcctctag cccttcgagg tcaaagagac cccctgaaag aagctaattt ttcacgattt
    52741 gcgtcaattt tctgacgaat tactgaaatg tccataaata ctcctttttt acatcatttc
    52801 attatagcat attttatcat ttctttccat cttttgctct aatccccttt tcatgaaaaa
    52861 agaagccttt gggcttccct tcttacaaga cttttgctga agtgcgagcg atttcttcca
    52921 cttgaatacc atttgcttca aatttttctt tcaaggctgg taaatcaatt gatccatcga
    52981 tttgcacttc gataatcacc ttaccatcct tacgcggaat attgactgta tgggagatat
    53041 tcaaattttc ttctacaatc aaagaaacaa tttttccaag aacaccaact tcatcttctg
    53101 taacaaagcg tacacgaatc ccttcttcgc cataacctgc aatttcaaga aaggcttgga
    53161 aaacgtcacg gtcagtaata actccgtata cttgatggtt atctacgaca gggagaatac
    53221 taatcttatt tttcaacatc agataagttg catcttctag actagcatag cctgagacag
    53281 tgacaacatc gcgaatcatg acatctttta cttttgtctt attcagaaga taattcatct
    53341 catagataga aagacttgtt gctttagatg gacttgcttg tgcaatggtt ccctcagtca
    53401 ccaaaccaac taattgatca ttttcgataa caggcagacg gtgcaaacct tgctctctca
    53461 tcaaatctgc tgcatgagat actgttgtat ctggactaat ataaactacc ttgcgggtca
    53521 taaaatcttt aactgccatg agacttctcc ttttctattc ttatccccat tatacaatct
    53581 ttttgtaaat ctatcaaacg cttacatttc tttttcgaaa ttcaaaaaag tatgaataag
    53641 ctagcaaaaa gagctctgaa atagagctct gtgaatgaag gtaagaaatt tttcattcga
    53701 ttttttcaat tattagaaat taagctttca atgtagatgc atatttgttt gcaatctcta
    53761 tccaccgact aaaaaggtcc cccggactat attgatgatt acttcgtaat ctccatctgc
    53821 cggctaaaac aatcctctgg atttgatgat tgcttcgcaa tctttatctg caacctaaac
    53881 tagtctccca gactataatg atgattactt cgtaatcttc atctgccgac taaaacaatc
    53941 cactggattg ttttagccac ctagatatgc ttttctgact tcttctgatg aggcgagttc
    54001 ttttcctgtt cctgatagga cgattttccc tgtttccagt acatatcctc ggtcagagat
    54061 tgcaagtgct ttattggcat tttgttcaat caagaggacg gttgttcctt gcttctgaat
    54121 atcttgaatg atatcaaaaa tctcttggat gaagattggg gcaagtccca ttgatggttc
    54181 atctaaaaga agaagttttg gtgttgacat aagagcgcgt cccatggcaa gcatttgttg
    54241 ttcccctcct gaaagagtag ctgcatcttg gttcttccgt tcttcaagac gaggaaagcg
    54301 tgagaaaacc ttcttcaagt tagcttgatt ttcttcacga tttttcttta agaaagctcc
    54361 catttcaaga ttttccataa cagtcaagcc aggaaagacg tggcgtcctt ctggaacttg
    54421 tgaaagacca cctgccacga ttttctgagc tggcattttt tggatttctt gacctaaaaa
    54481 ttcaatcttt cctgaacttg gtcgaaccaa acctgacaag gtgcgaagaa tagttgtctt
    54541 acctgcaccg ttggcaccga taagggaaac aacttctcct tcattaactt caaagcttac
    54601 atcacggact gcttggatca taccgtaatg cacagaaaga ttttcaactt ttaacataga
    54661 cattaggctt cacctcctag ataagcttcg ataacgcgtt tattggtctt aatttcgtct
    54721 ggagttcctt gagcaattaa acggccatat tcaagtacgt agatacgttc tgttacttcc
    54781 atgaccagat tcatatcgtg ttcaatcaac atgattgtaa tcttaaattc atctttgata
    54841 cgacgaatta actcagtcaa ttcggctgtt tcctgtgggt tcatacctgc tgctggttca
    54901 tctaagaaga gaattttagg ttccgtagca agggcacgaa caatttccaa acgacgttgt
    54961 tgtccgtagg aaagattttt agcaagagtc tctgcatcac catctaaatc aaagattttc
    55021 aacaattcca aagctttagc ctttaattct ttttcactct tgtaaaaagc tggtaagcgt
    55081 aagaaactag taaaaacatg ttgtttgtga tggtttccaa aagcaatcaa aacattgtct
    55141 aaaactgtta aatctttaaa gagacggata ttttggaaag tacgtccaag tcccaaagag
    55201 gcaatcttat aaggtgattt cccattcaaa aggtgaccat ctagggttac tgttccctcg
    55261 cttggttcat aaacaccggt caaaaggttg aaaagggtgg ttttcccagc tccgtttgga
    55321 ccgattaatc caaccagttc cccttcgttc aattcaagag tcacatctcc aacagctgtt
    55381 agaccaccaa aatgtttggt taactgtttt acttcaagta atgccattag ttttgttcct
    55441 ccttcttaga ttttttaaag aaacgtgata ggctcagttc ccatgttcca aggagtccac
    55501 ctggtctgaa aatcattacc aataccaagg ccaaagcgta aataatcata cgcacactag
    55561 caacatcttg gagaagcata ttcaaaattc ccagaacaat agccgaaaca atcgcacctg
    55621 taatggaacc gagtccacca aatacaacaa taatcaaaac gttgattgag ttgatgaagg
    55681 tgtaatcttt cggtacaaca gacccgataa atcctgcctg aagtgaccca gcaatacttg
    55741 cagtaatggc accaaagaca aaagcgatga ttttaatttt agtcgtatta accccaactg
    55801 actcagcagc gatttcatct tcacgaacag agagggttga acgaccaatt gggctacgca
    55861 agaagttcaa ggttgcaatg gttgtaatca cgacaaagaa gtaaaccatt tgccaagttg
    55921 taaagttagg aatccctaag atacctgccg caccatttgt aaggcttcca ccattgatga
    55981 taaagatacg gataatttca gaaacaccca gagttgctac cgcaagatag tcccccttca
    56041 agcgcaaggt tggaatgccg acaagtaagg caactgctcc tgaaagcaaa gcccctacaa
    56101 gcatagctcc aaagaaggca ccgtaggttg gtaatttaga accaataata gctgctgcat
    56161 aggcaccaat cgccatgaaa ccagcatgac caagtgaaaa ttgtcctgaa aaaccaacga
    56221 ttaagttgag accaacagcc aaaataatat taattccaat ttgctgtaaa atctgtacat
    56281 agaatagatt aagtactccg actgaaacca gtacactaat caagctatag ccagctaaca
    56341 aaaggagtaa ccatagaata ttaactttta aattttcctt catcgtttac accttctctt
    56401 tcacattctt accaaggata ccagctgggc ggacaatcaa gatcaacaac aagattccat
    56461 aaacaatggc atcacggaaa tctgacatcc caaaggcagt cgcaaaggtt tccaatagac
    56521 caatcacaaa gccaccaaga gccgcaccag gaataattcc gataccacca agtactgcgg
    56581 caacgaaaga tttaagacct ggagtaaccc ccatcaaagg ctcaagagag ttataataaa
    56641 gagcaatcag aacaccagcc gcacccgcaa gagcagaacc caaagcgaag gtaaagctaa
    56701 tcgtacggtt tacattgatc cccatcaatt gcgccgcgtc gctatctact gatactgcac
    56761 gcatggcttt ccccatctta gtcttttgga caatgacttg taacaaaatc atcaaaatca
    56821 aggaaatagc caaaatcatt aactgcacat ttgttaagct aattggtccc aaatcatatc
    56881 gaactgtttg aatcgcttga gggaaggcac gggtattggc accaaccaga tagaccattc
    56941 catactccaa taggaaagaa accccaatag ccgtaatcaa aacagcaata cgagtagagt
    57001 ggcgcaaagg tcggtaagca agaaactcaa tcacgacacc aagaatagct gtcgctagca
    57061 tagctacaat aagcgctaca aagaaattca tttggaaaga attgatcaag aaataaccga
    57121 taaaggctcc catcatataa atatcaccat gggcgaagtt gatgagcttg ataattccgt
    57181 aaaccatggt atatcctagg gctaacagcg cgtaaacact acctagaatc aaaccattta
    57241 cgagttgttg gagcataaga ttcactcttt ctatttataa ttccgagggg tttccctcac
    57301 tttttgatag gttcttatac tcaatgaaaa tcaaagagca aactaggaaa ctagccgcag
    57361 gttgctcaaa gcactgcttt gaggttgtag ataagactga cgaagtcagt cacatatata
    57421 atccaaggcg acgttgacgc agtttgaaga gattttcgaa gagtattaaa tatcgaaaca
    57481 gggagtgagt caaaggctca ttccctattt caacattttt ctattatggt tttacaactt
    57541 ctgctgcttc aactttacca ttgttcatgg tcatcatgta agcagttttg actgtgttgt
    57601 ggtctgcatc gaagcttgtt tgaccagtta caccttcaaa atcttttgtt ttagcaaggt
    57661 tatccttgat ttcacctgaa tttttagcac cttttgctgc gtttgctaca aggtgaactg
    57721 aatcataagc caaggctgca aatgttgaag gctcttcatt gtacttagca cggtaagcgt
    57781 caaggaaggc tttagcttta gctgaaactt ctacagtagt tgagaagcct gagataaagt
    57841 agatgtttga tgctttttca gcagttgctt gttgtacaaa ctcctcaccg ttgaatccat
    57901 caccaccaac gattggtttg tcaattccca taccacgcgc ttggtttaca atcttaccag
    57961 cctcattata gtaaccagga acaacgatag catcaaagtc tttccctttc atttttgtaa
    58021 gggctgcttg gaagtctgtg tcacctgcta cgaaagtttc atctgcaacg atttcaccct
    58081 tgtatgactc gcggaaagat ttggcaatcc ctttagcata gtcactggca ttgtcagtgt
    58141 aaagaacaac tttcttagca tttaattttt cagaaacata gtttgagata atttttcctt
    58201 ggaagctatc ttggaaagtt ccaataaaga ggtaatcttg acctttagtc aatccatctt
    58261 gagtcgcact tggtgagatc aagggaacac ctgcttttgt agcgttcgct accgcagctg
    58321 cagtcgcacc agatgttgca ggtcctacga ctgctgatac tttagattgg gttacaaggt
    58381 tagttgtaac tgaagcagcc tcagctgttt cagacttatt atctttatcg actacttcga
    58441 tttgttttcc atcgatacca cctgcggcat tgatttcatc aacagccaat tgggcacctt
    58501 tttgttcagc tgttccgtat gcagctaaag aacctgattc ttcaaagtta aacccgattt
    58561 taattgtctt ttcctctact gagttaccag cagtgttgac tgctccagac ttcacttctc
    58621 cacaggctgc aagaagtgct acacttgcaa gcgccacaaa cgatagggca aattttttct
    58681 tcatcttttt gtctccttat ttcttaaata gtctgttaag aatataccga attatcagaa
    58741 aattgtcaat gttttccttg aactttttcg atgataacgt tttcctatcg ataaagattg
    58801 cccacaaagg gtgtttccaa ctcttggata tgacaaaccc taactttttt aataaatttt
    58861 tccttgctca agcgtccgac caattgctcc acttcttgag ttggaacata gagttgtaag
    58921 taacgatgtt tcttggaatg ataggtaata tctccataat cctgcagttt tttggcatca
    58981 cgattatagt aaagatagat aatcaagcca gagcgattga ctttttcaaa catgataaat
    59041 cctctttcta agaaatctct ccctattata ccaaaaaaag caaacccagt cgagtttgcc
    59101 ttctatcatc attagttcaa tgaattgttg gccataattt catcaataaa gccatattca
    59161 agtgtttcct gggcgctcat ccagttatca cgttctgcat ctgcatggac tttttccatt
    59221 gactgacctg aattttcagc caagattttt tccaaggtat tacgagtttt gagcaagtgt
    59281 tctgcagcga tagccatatc agtttgttgg gtaccaccac ctgtaccgcc cattggttgg
    59341 tgaatcatgt attcagcatt tggaagcatg aaacgtttgc cttttgctcc acttgatgcg
    59401 atgactgttc ccatagatgc agccattccc ataacaatgg tttggacatc tgccttgata
    59461 aagttcatgg tatctacgat tgccaaacca gctgaaacag aaccacctgg tgtattgaca
    59521 taaaggtaaa tatcttttgt actatcttgg gcatccaaga aaagcaattg ggcaataaca
    59581 gagttagcca tattgtcttc aaccggacct gtcagcataa tgatgcggtc tttgagaaga
    59641 cgtgagtaaa tatcgtaaga acgttctcca cggcttgttt gttcaataac tacaggaatc
    59701 attcatttct ccttttgagt tttaattttg ttggtcaaat gactgaagat aagactatta
    59761 taatatcttg gtcaaaaaag gtcaaatttt tgctctgctt tcattagaca gaaacaaaaa
    59821 cccaacctcc tttcgtgact ggaaatactt ttccaagtca ttcttctttt cgatcttatt
    59881 ttgtaccgaa caagcggtct ccagcatctc caagacctgg aacgatataa ccgtgttcgt
    59941 tcaaacgttc atccaaggct gctgtaaaga tttctacatc tggatgagct tcttgaaggg
    60001 cttttacacc ctctggagca gatacaaggc agacaaattt gatatttgat gcgccacgtt
    60061 ttttaagaga atcaacagcc aagattgctg agccacctgt tgccaacatt gggtctacta
    60121 caaaaatttg acgttggtca atgtcctcag gcaatttcac caagtattca actggttgaa
    60181 gtgtttcttc atcacggtac ataccgatgt ggccaacttt agcagctgga accaagctca
    60241 agagaccatc aaccatcccg atacctgcac gcaagattgg gacgatggcc aatttcttac
    60301 ctgccaattg tttttgaact gtttttgtaa ttggtgtttc gatttccaca tcttctagtg
    60361 gaagatcacg aagtacttca taccccatca acattgcaat ctcatctact agctcacgaa
    60421 aagcttttgt agaagtatct gtacgacgca agattgacaa tttgtgttga atcagtgggt
    60481 gattaataac ttcaattttt cccatttttg gaattccttc tttcaattta ttcttcttat
    60541 tataccaaaa aacggtttaa aaatctttct aagccattta tttttgataa tttttacatt
    60601 agatcagcct ctttaagagc tgtctgtact gtctcaagtg gtaaatgggt caattctgtc
    60661 cctttttctt gataaaggta ttgggcgtag tcgtccattc ggtactggtt gatataaacc
    60721 acgcgcttgc agccgacctg aagcaattgt tttgtacagt tgagacaagg aaaatgggtt
    60781 acataggctg taaagccttt gggaacacca cgctcagcac cttgaaggat agcattgacc
    60841 tcagcgtgaa gggtgcgaac acagtggcct tcaatgacca aacattcgtg atcaatacaa
    60901 tgctcagtcc ctgacaccga accattgtaa ccagtggaaa taaccttatt atcttttacc
    60961 agaatcgcgc ccactttagc acgtttacaa gtggaacgat tcgcaattag tagggcttgg
    61021 gctgcaaaat actcatccca ggccagtctt ttttcagtca tctcttttct cctttttctc
    61081 tattttttaa aaaatggtaa acctaaatct gcaatctttt cagctggtac cttcatgcca
    61141 tccttgatcc attttagaag gacagagacg atggctgagc tccagaagga atgaagataa
    61201 gagctgacac cttttgattt cccatggtat ttttctagaa attcctgcat ggcttggaca
    61261 aagatttttt ccagatggta atccaaggcc aattgaatta ctctagcttc ctttctggcc
    61321 tcccggaaaa ggtgaaccca aaccaaataa aggtctgtct ttaaatcgta atgatgcagc
    61381 tgttccataa tattgtggac agttcgttta aagacgctct ctaaaatttc ctctttggag
    61441 tcataattgc gataaaaggc cgcacgcgaa acacctgcac gtttgaccaa ttcagaaata
    61501 ctaatcttgg tcagctcctt tttttccaag agttgcaaga gggctgtttc aatggcttct
    61561 ctggttaata aattggattc ttggtttgat tttctgagat tttcaagaga cttttcagag
    61621 attctacgtt cagacataac attttctttc tacttgtcac aacagacgga tgatgctttt
    61681 gtttcaagag ttttcatgat ataattgtaa aaaaagacag aacctttgtc aatgtataac
    61741 tgacaaagat ggagaatttc tatgacttgg aagattattg ctgactctgg ttgtgattat
    61801 cgtcaactgc caacaccagc tattaacaca acctttgtaa gtgtcccctt aaccattcaa
    61861 gtagctgatc aggtctttgt tgatgacgcc agtctcgata ttgaccaaat gatggaaacc
    61921 atgtatgcaa ctgcagaagc ttcaaaatca gcttgtccaa gcccagatga ctatttgcga
    61981 gcatttgaag gtgccgaaaa cattttccta gtaaccatca caggtaccct ttctggcagt
    62041 cacaatagtg ctcaactagc aaagaatatt tatctggaag accatcctga cactaagatt
    62101 catgtgattg atagtttatc tgctggtggt gaagttgacc tactcgtaga aaaattgaat
    62161 gacttgattg accaaggctt gtcttttgaa gaagtggttg aagctatcac cgcctatcaa
    62221 gaaaaaacta agttgctctt tgtcctagcc aaagtcgata acttggtgaa gaacggccgt
    62281 ttgagcaagc ttatcggtac ggtcgttggc cttctcaaca ttcgtatggt cggaaaagct
    62341 agtgaaactg gaactctcga attgctacaa aaagcaaggg gatcaaagaa atcagttcaa
    62401 gctgcctatg atgagttagt aaaagctgga tatgctggtg gccgtattgt catggcccaa
    62461 cgcaataacg aaaaatgttg tcaacagctc tcagagcgaa tccgtgaaac cttcccacaa
    62521 gcggatatta aaattctacc aacctctggt ctctgcagtt tctatgcaga agagggcggt
    62581 ttgctgatgg gctatgaaat tgattaattg cattcttgac aagaggtgac catcatctct
    62641 tgtttttttg tggtacaata gagctatgaa acattttgat actattgtca tcggtggggg
    62701 acctgctggt atgatggcta cgatttccag tagcttttat ggacagaaaa ccctcctcat
    62761 cgaaaaaaat cggaaacttg gaaaaaaatt agctgggact ggtgggggac gttgcaatgt
    62821 gaccaacaat ggtagcttag acaacctgct agctggaatt cctggaaacg gacgctttct
    62881 ttacagtgtt ttctcccagt tcgataatca tgacatcatc aactttttta cagaaaatgg
    62941 tgttaaactt aaggtcgaag accacggacg cgtctttcca gccagtgaca agtctcggac
    63001 tattatcgaa gctttggaaa agaaaatcac cgaactaggt ggtcaagttg ctactcaaat
    63061 agaaatcgtt tctgttaaaa aagtagataa ccagtttgtc cttaagtcag cggatcaaac
    63121 cttcacttgt gagaaactca ttgtcacaac aggtggtaag tcttatcctt cgactggttc
    63181 gactggtttt ggtcacgaga ttgctcgcca ttttaagcat accatcaccg atcttgaggc
    63241 tgctgaaagt cctttattaa cagattttcc acataaagcc ttacaaggga tttctttgga
    63301 cgatgtgacc ctaagttatg gtaagcatgt catcactcat gatttactct ttacccactt
    63361 tggtttgtca ggtcctgctg ccctacgcat gtctagcttt gtcaaaggtg gggaggttct
    63421 ctcactcgat gttttgcctc aactttctga gaaggacttg gttacatttc tagaaaaaaa
    63481 tcgggaaaaa tccttgaaaa acgctttaaa aaccttgtta ccagaacgct tggccgaatt
    63541 ttttgtacaa ggatatcctg aaaaagtcaa acagctgact gaaaaggaac gagaacagct
    63601 tgtccagtcc attaaagaac ttaaaattcc tgtaactgga aaaatgtccc ttgcaaagtc
    63661 ctttgttacc aagggtggag tcagtctcaa ggaaatcaat cctaaaaccc ttgaaagtaa
    63721 gctggtacct ggcctccact ttgcaggcga agttatggat atcaatgccc acacgggtgg
    63781 ctttaacatc acttctgccc tctgtaccgg ctgggtggcg ggaagtctgc attatgatta
    63841 aagattaaag gttgtgaaga atgaacagaa gagaggcagt cgaatttgtt aacatgtgta
    63901 tgattaaaaa cggagataag gtcctggtcc aagaccgagt tagtcccgac tggcctggca
    63961 ttacttttcc tggtggtcat gttgaacgtg gcgaatcctt tgtcgatgct gtcattcgtg
    64021 aagtgaaaga agaaactggt ctgatcattt ccaaacccca actctgtggt atcaaaaact
    64081 ggtatgacga caaggattat cgttatgtcg tcctttttta caagacagaa cactttactg
    64141 gtgaactcca gtcttcagac gaagggaaag tttggtggga ggactttgaa aatctttctc
    64201 atctaaaact tgcaaccgat gatatgtctg atatgcttcg tgtgtttcta gaagaagatc
    64261 tcagtgaatt cttttactac aaaaacggtg acgactggct ttatgatttg aagtaaaaaa
    64321 taggctagga aattcctagc ctattttttc tgcatttgtc tgaacgtaag ctgcaatggc
    64381 atctgacgtg tactgggctg ttccagaacc aaacttgtca atgttttcct taaactctgg
    64441 gttgtagacg taacctttac cgatatgacc gaatacctca atagagcagt caaatccata
    64501 agtgcgaatg gcttgcaaga gcttggctgc ttgctcttgg ttttcggttg ctgttgcagg
    64561 taaaccaact tgaagatttt gtgccaaagt ttgaaagact tggttaaagg cggccgtagc
    64621 ctcgtcttcg tgaccttttt ggcgttcgag cgcttgtccc atgacttctt gaccatattt
    64681 ctctaccgct tcttggtggt atttttgatt gtcttgatag ctaaatcccg tgaatttttc
    64741 ctcaatggtc atttttcttt ctcctttttg ttcttgaata gttttttgca aggtggaaat
    64801 caaggtatcc agatgttgcc tttcgcgagt tagatagtcc aactgcctag ttaaatgggg
    64861 caataaatct gtcctttctt cctttaacag ctctgctatt ttctctaaag aaaagcctag
    64921 atatttgtag taaagaatga cctgaaggcg ttccaaatcc tcttgactat aggttcgata
    64981 gccgttttcc gactttaagg ggaccaagag tcctatcttg tcatagtgat gcagggcagg
    65041 gtcttgacag agacacctga aagctgcgca gcttctttta tatggtacat gatttcctcc
    65101 ttacaatgat agtataaccc ctccccttag gtcagagtca agcgtttttg agaaaggtgt
    65161 gaaaacttga aaatggtttt cttgacagac cttagaaaac atgataggat agtcaagtct
    65221 atcaatcaaa cagaaggcta tttgacaact caagtagctt tttcttattt tgaaaaagga
    65281 gatcagagtt taactatgtc agaaaaatca caatgggggt cgaaacttgg ttttattcta
    65341 gcatctgctg gctcggccat cgggcttggt tccgtttgga agtttcccta catgactgct
    65401 gctaatggcg gtggaggctt tttactaatc tttctcattt ccactatttt aatcggtttc
    65461 cctctcctgc tggctgagtt tgcccttggc cgtagtgctg gcgtttccgc tatcaaaacc
    65521 tttggaaaac tgggcaagaa taacaagtac aactttatcg gttggattgg cgcctttgcc
    65581 ctctttatcc tcttatcttt ttacagtgtt atcggaggat ggattctagt ctatctaggt
    65641 attgagtttg ggaaattgtt ccaacttggt ggaacgggtg attatgctca gttatttact
    65701 tcaatcattt caaatccagc cattgcccta gtagctcaag cagcctttat cttattaaat
    65761 atctttatta tatcacgtgg ggttcaaaaa gggattgaaa gagcttcgaa agtcatgatg
    65821 cccctgctct ttatcatctt tgtttttatc atcggtcgct ctctcagttt gccaaatgcc
    65881 atggaagggg ttctttactt cctcaaacca gacttttcaa aactgactag cgctggtctc
    65941 ctctatgctc tgggacaatc tttctttgcc ctctcactag gggttacagt catgttgacc
    66001 tatgcttctt acttggacaa gaaaaccaat ctagtccagt caggaatctc catcgtagcc
    66061 atgaatatct cgatatccat catggcaggt ctagccattt tccaagctcg atcccccttc
    66121 aatatccagt ctgaaggggg acccagcctg ctctttatcg tcttgcctca actctttgac
    66181 aagatgcctt ttggaaccat tttctacgtc ctcttcctct ttgcgactgt cacttcttct
    66241 gtcgtgatgc tggagatcaa tgtgggcaat atcaccaacc aggataacag caaacgtgcc
    66301 aaatggagtg ttattttagg aattttgacc tttgtctttg gcattccttc agccctatct
    66361 tacggtgtca tggcggatgt tcacattttt ggtaagacct tctttgacgc tatggacttc
    66421 ttggtttcca atctcctcat gccatttgga gctctctacc tttcactttt tacaggctat
    66481 atctttaaaa aggctcttgc aatggaggaa ctccatctcg atgaaagagc atggaaacaa
    66541 ggactgttcc aagtctggct cttccttctt cgtttcttcg ttccgtcatt ccaatcatca
    66601 tcattgtggt cttcattgcc caatttatgt aatcaaaaag gacttgagta gtgaactcag
    66661 gccctttctt tttatggatg gctaacaatc aattccaaac cttgcccttc cagagtccaa
    66721 gcttcaacat cacttggtag gataaagtgg ctgccttttt gaattggata atttttcccg
    66781 tcaacagtta gctgaccttg accagctaag acactcaata agctgtagtc agctgtcttt
    66841 tcaaagtcaa cttttccagt aatttcccac ttgtaaactg cgaagaaatc attagataca
    66901 aggagagtgg aacgcaaatc atctgcttta acagttacag gacggctatt tgctggctca
    66961 ccaatgttca agacatcgat ggatttttca agatgaagtt cacgcaagtt gcctttgtca
    67021 tccttgcggt caaagtcata gacgcgatag gtggtatcgc tagactgctg ggtttcaagg
    67081 atgaagatac ccgccccgat agcgtgcata gtcccgcttg gtacatagaa gaaatctcca
    67141 gccttaacag ggactttggt caacaagtca tcccagttct tgtcctcgat ttgctggcgg
    67201 agttcttctt ttgacttggc attgtgaccg tagataatct ctgaaccttc atccgctgcg
    67261 ataatgtacc agcattctgt ttttccgagt tcgccttcat gctcgagtcc ataagcatcg
    67321 tctgggtgaa cttggacact gagccagtcg ttggcatcga ggatcttggt caaaagtgga
    67381 aatacaggtt ctggacgatt gccaaataat tcacggtgtt ccgcatacaa agtagcaaga
    67441 tctgttccct cgtaacgacc attggcaact ttagagactc catttggatg ggctgagatg
    67501 gcccaatatt ctccgatttt ttcacttggg atgtcgtagc caaactcatc acgtagcttg
    67561 gctccacccc agattttttc ttgcataact gattgtaaaa ataatggttc tgacatgtcg
    67621 atctcctgtc tgatttttct cccctcatta tagcaaaaaa agagttcgaa ttgaactctt
    67681 ttttacatct tataaagcag ggagaagatt ttataaaaat agtaaacaaa tgtgctctac
    67741 tcgatgctta caccattgct ataaatgaca tgtaccaata gaaggacttc ttcttgctac
    67801 gtttgagagt cccatttcct acattatctc gatctacata gataaagcca tagcgcttat
    67861 tcatttcccc tgtgccagct gaaaccgaat cgatacagcc ccatgtcgta taaccaagca
    67921 agtcaacccc gtctttgtaa atggcatctc gcatggcctt gatgtgggcc tctaagtaag
    67981 taatccgata gtcatctgct acataaccat tctcatccgg tgtatccata gcaccgagtc
    68041 cattttctac gataatacta tactaaaatc aaaaagcatt atataatagt gatatgaaat
    68101 caactaaaga agaaatccaa accatcaaaa cactttttaa agactctcgt acagctaaat
    68161 atcataaacg ccttcaaatc gttctatagt aaaacgaaac aagaacaggg caaatcgatc
    68221 aggacagtca aatcgatttc taacaatgtt ttagaagtag aggtgtacta ttctagtttc
    68281 aatttattat atttcgtctg atgggcaaat cttataaaga gattatagaa cttttatagt
    68341 agtttgaaat aagatgtgaa caactctatc aggaaagtca aactaattta tagaaatatt
    68401 ttagcagcta aggtgtactg ttatagattc aatacactat agactgtaat caaacaacga
    68461 tttggcgaaa tgtaaaaaaa tatgaggagt tcgaactcga ctctctcctt caagaaacac
    68521 gtggtggccg taaccatgca tatatgacga ttgaggaaaa gaaagtcttt cttgcccgcc
    68581 atttgaaggc tacagaggca ggagaatttg ttacaattga tgccttattt caggcttata
    68641 aaaaggagtt aggtcgttcc tacacacgtg atgccttcta tcaactgttg aagcaccatg
    68701 gttggcgaaa tattatgcca cgtccagaac atcctaggaa agcagacgct caaaccattg
    68761 tcgcgtctaa aaataaaatc tcaattcaag aagaaaagaa agcgctttaa aagcagtaga
    68821 cgttttcgta aggttcgctt gatgtaccaa gatgaggctg gtttcggtag aatcagtaaa
    68881 ctgggatctt gttgggctcc aataggagta ggtccacatg tccatagtca ctatatacga
    68941 gaatttcact attgttatgg agctgttgat gcccatacag gcgaatcatt tttcttaata
    69001 gctggtggat gtaatactga gtggatgaac gcctttttag aagagctttc acaagcttat
    69061 ccagatgatt atcttttact cgttatggac aatgctatat ggcataaatc aagtacctta
    69121 aagattccga ctaatattgg ttttaccttt attcctccat acacaccaga gatgaaccca
    69181 ttgaacaagt gtggaaagag attcgtaaac gtggatttaa gaataaggcc tttcgaactt
    69241 tggaagatgt catgaatcaa cttcaagatg tcatacaagg actggagaag gaggtgataa
    69301 agtccatcgt taatcggaga tggactagaa tgctttttga aagcatatga gtattatatg
    69361 caatttcttt atataaaaag accggattgc tccgatcttt caatagttca tattctcaat
    69421 ttctatttta aaaatagcta aggttaacgt caaatgacta cgcgacctat ttcatacgat
    69481 aaaaatcaag cactagacca gcaggtcctt gaactaataa ggactctgtt ccccaatcgg
    69541 ttacagttgg tccgtgtaaa acctttatac caagctcgtt caaccgtttg tagttctggt
    69601 ctacatcctc aacctcgata tgaataatga ttcctgactg aaagttttcc aaaggaacca
    69661 aatgattttg tgacaacata aggcagtgac taccaatcgt aaactgagca aaaccatcat
    69721 cagcataatc tgccttttta tccaaaatat gctccaagtc agcacagact tggggaacat
    69781 ttgaaacgat aatatctaat tgatttaaat tcatttactc tcctccataa aaagaccgga
    69841 ttgctccgat cttttaaagt tctgctctat gaaaatcaaa gaataaagtc tacaagtttc
    69901 atatttgatt ttcggcgaga ggaattattt aattgcgcgt gattgcaatc cttcttcttc
    69961 caagaagaga cggaatggta cgagttcttc tgcttcgtat ttttccttga aggctttgat
    70021 agcttcttct gagtgaagtt ttggatccaa ttcaagtact tctactggaa gtggacggtg
    70081 ttgagtgatg cgagcatcga tgacaacagt tttaccttct ttgttcaatt taacagcttc
    70141 tgcaacaact gcatcgatgt cttcgatacg gtcaactgtg aatccaacag ctccttgagc
    70201 ttccgcaatt ttagcgtagt cagcgtttgt gaagtctaca ccaaacaagt gtttgtttgt
    70261 atcttcgtat ttgttcttga tgaagccgta ctcagcattt gagaagacaa ggttgataac
    70321 tggaaggtcg tattgaacgt ttgtgataac gtctgggtag cacatgttga atgctccgtc
    70381 acccatgatg ttccatactt ggcgatctgg attgtctttc ttagcagcga taccaccagg
    70441 aagggcaata cccattgtcg caaagagtgg agatgtacgc cacatgttct taggtgtcat
    70501 gtgaaggtga cgagtagatg tttgagtagt gttacctacg tcgattgagt agatagcgtc
    70561 ttgatcagca tgtttgttga ttgcattgta aacttgatac aattgcaatt caccctcagt
    70621 tttaccttcg agtttgttca tgtaatcacg ccagttttgg ttgttcttaa cgtttgcacg
    70681 ccaccatgga gttgattcaa ctgggtttac tttgtcaagg atagctttag ctgcttgacc
    70741 agcatcacca aggattgaag cgtcaagagc atgacgttta ccaagtttgt aagggtcgat
    70801 atcgacttgg atgaattttt cagtgttctt gaatgcttcg taaacttcag cgaatgggaa
    70861 gtttgaacca aggaaaagaa ctgtgtctgc ttcaaagacc acttcgttgg ctggtttcca
    70921 accaacacgg taagcagaac ctgtcaaacc ttcatagttc cattcgaaag cttcaaagtt
    70981 tttaccagtt gtgatgattg gtgctttgat tttacgtgac aattcagtaa tcacttcacc
    71041 agctttaaca ccaccaaatc cagcatagat aactgggcgt tcagcattgt tcaagatttc
    71101 aacagctttg tcgatttcaa cttcgttcaa agcaggagcg atgaatgagc gttcgtatga
    71161 acctgaaccg tagtatgagt tttcatcgat ttcttggaaa ccgaagttta ctggaatttc
    71221 aacaacagct ggaccttttt tagaaactgc agcacggcag gcttcgtcaa ttacttttgg
    71281 caattgctca gcgtaagcta cacgtttgtt gtaaacagca ataccgttgt acattgggtt
    71341 ttggttaagc tcttggaaag catccatgtt caattcgtta actggacgtg atccaaggat
    71401 cgctaggaat ggagtgttat ccatagctgc atcgtaaaca ccgttaatca agtgagtcgc
    71461 acctggacca cctgaaccaa ctgcaacccc gattgagccg ccgaatttag cttgcataac
    71521 cgctgcaaga gcacctgtct cttcgtggcg aacttgtaag aaacggatat ctttgtcttc
    71581 agccaaagcg tccatcaatg agctgagtgt tcctgatggg ataccgtaga ttgtatctac
    71641 gccccatgtt ttcaatacgt taagcattgc tgcagatgca gtaattttcc cttgagtcat
    71701 aatgataact ctccttcaat ttttttagac ttggagaata cgattacata gaattggaaa
    71761 cgttctccaa atttttacta ttccactgta tcatatttat gctgactttt ctaaaaatct
    71821 gctcaaaact ctctattctc tattctaata cagttttgaa agtgttgtca tttctgtttt
    71881 ataacaaaga aatctagtca ttacttttag tctattttac taaaatttaa cagaagggaa
    71941 ctggtcagaa cagatacaga actaaaggcc atggctagac ctgccaattc tgggttgaga
    72001 gccagtccaa cacctgaaaa gactcctgct gcaatcggaa ttccgacaac attgtagata
    72061 aaagcccaga aaagattgag tagaattcga tgaaaggttt tcttactcat atcaaaggca
    72121 cgaaccactc ctaaaagatt attggttgtc aacaccaaat ctgctgactc gatggcgata
    72181 tctgttccag cacccatagc aattcccaca tctgctacac taagggcagg agcgtcattg
    72241 ataccgtccc caacaaaggc tactttccct gactgttgca gtttatggat ttcatgggct
    72301 ttttcttctg gcaagacgcc tgcaatgacc tcttcaattc cgatttgatc tgcaatagca
    72361 cgcgccacac cagcattgtc tcctgtcagc atgactgttc ggagaccacg tttttttagc
    72421 tgactgatgg ctagcttagc attttcctta ggaatatctt gcaaagcaag caagcctttg
    72481 atttcattgt caacagctaa gaacacaact gtcttagctt ctttttctag ttcttctagt
    72541 ttatcttgat aagtattaga aatatccatg ccatccagca ttttagcatt tccaagtaaa
    72601 acttgttttc cattgattcg ccctgaaaca cctttcccgt gcaaggactg aaaattttcc
    72661 acagtttgaa actcaagtcc agcttcactc gctcgcttaa cgatagcctc agccagtggg
    72721 tgttgagaag catcttccaa ggaggctgcc aatccaaaca cttctacttc gtcgccgatg
    72781 atatctgtta ccacaggttt cccttccgtc aaagtcccgg tcttatcaaa gacaagagtt
    72841 tgaactttct ggatttcctg taagacagtt ccatttttga ggagaacccc catcttggca
    72901 ctacgtcctg tccccaccat aagggctgtc ggtgttgcaa gtcccaaggc acaaggacag
    72961 gcgataatca aaaccgccac tccgtagaga agagaggaca caaagctagc tccaagcaca
    73021 accacactat ccctgagcaa gacgaaccaa acccaaaagg tcatgattcc taaaatgaca
    73081 actactggta caaaaatccc tgaaatctta tccgtcaagt cctgaatcgg cgcacgactt
    73141 gtctgagctt tcttcacaaa atccacaatc tgagccaaaa cagtctctga gccaactttt
    73201 tctgctctaa agacaagcgt tccactatga ttgatggttg agccaatgac agtatctcca
    73261 actgtcttgt ccacaggcag actctcacct gtcaccatgg attcgtcaat actagagaca
    73321 ccttctacta cgacaccatc aacagcaatc ttttcaccgg gacgcactcg aatcaggtcg
    73381 cctaccttga cttgttccaa aggaacttgg acataactat catcactcaa gacttctgcg
    73441 gttttagctt gcaagtccag taatttctcc acagcttggg acgtattttt tctcattttt
    73501 tcctcaaaaa ctgctcccca aagaacgaaa aagaggataa atccagcact ttcgaagtaa
    73561 acagggagac cagcaaagag agcaactagg ctatagaaat aagccactag agttcccagc
    73621 gcaaccaagg tatccatgtt ggcattgtgc tttttaaaac tggcccaagc actctggata
    73681 tatggcttac ctgcaactaa cataataggc gttgttgcta gaaaggttcc ccaatgcatg
    73741 acttgatgac taatgctacc tgtcaacatc ccaatcatga gaatcacaag aggcacagta
    73801 aagatactaa taatccaaaa acgttgcagg agagatagag attttcgagt cttctcaacg
    73861 actgtatagc ttcccttttg catcttcatg ccacaagaaa attcatgtcg ccctaattct
    73921 tgaggtgtaa aacgaatgac tttctcctca tctacgccga ttggttccaa gataccttct
    73981 tcttcaaaca gaatttcctt ataacagttt gaaggagtag cacgatgaaa ggtaatctca
    74041 gctggaattc ccttttgaag ctggatatgg gttggatgat agcctttttc agctcggata
    74101 cggatttttt gaatgccatt ttctaagctt gctttcacaa tttctgtcat agtctccacc
    74161 tactctacaa tcatcttgcc gtgcatcatg ttcataccac aagcaaagcc aaactctcca
    74221 gcctgctcag gcgtgatttc cactacatac tcttccccca ttggcaggtt cgcatgtaca
    74281 ccaaaatctg gaaaaacaat ttgatccaga catggtgaag gatccttgcg atcaaagaca
    74341 atgcgtgctg gcactgattt cttgaggaca atcaactcag gagtatagcc tcccatgact
    74401 tccactcgaa tctcttggta tccgtttttt tgctgggctt tttgtccaga tttttcaggc
    74461 tttttgaaaa accaaaacaa gataaacgcg ataagggcaa tacaaataat ggttacaata
    74521 ctatttaaca tgacgtttcc tttacataca attacatctt acttctgtta cagcacttga
    74581 tttcttctct gaaatcacag cttccaagtc ttccaagtca gtctgagtaa attcacattc
    74641 tacaatcaag tcagccaaca aattcctaat cctacgggaa caaaccttgt ctttgatatc
    74701 ttggacaagt aaatcccgac tttggtctag agttaaaagg gctgaataaa caaaggactt
    74761 gccttctttt ttccgagtca aacactcttt ctcaactaga cgagccaaaa gtgtctgaac
    74821 cgtggacttg gaccagtcaa accgctctgc caaaacccta atcaaatccg tactggtctg
    74881 ctccccctgc atccaaataa tcttcatgac ctgccattct gcatctgaaa tctgcattac
    74941 catacctcca aaatctacat ttgtcaatta cactcatcag tatactctta aaatctacat
    75001 ttgtcaatta tagaaataat attttcttcg aaaaatagaa ttttaatcat ttgaaaaacg
    75061 atttgcagtc aaatattact atataaacaa taaaaatatg ctatactaaa gaaaaaagaa
    75121 aacaaccact aggggtgcgt aaagctgaga ttaacgactg ttagatccct ctgactcaat
    75181 ctaggtaatg ctagctgatg gaagtggaaa tgataatggg gactagcagt cttctattgc
    75241 ctttctaaaa cagactagct tgttcttaag aatacaaact tcagttggtt gggaggtttt
    75301 agatgactta tttacccgtt gctttgacca ttgcagggac tgaccctagt ggtggtgctg
    75361 gcattatggc agatttaaag tcattccaag cgagagatgt ctatggaatg gctgttgtaa
    75421 ccagtcttgt cgctcaaaat accagaggtg ttcagctaat cgagcacgtt tctcctcaaa
    75481 tgttgaaagc ccaattggag agtgtctttt ctgatattcc acctcaggct gtaaaaactg
    75541 gaatgttggc tactactgaa atcatggaaa tcatccaacc ctatcttaaa aaactggatt
    75601 gtccctatgt ccttgatcct gttatggttg ctacaagtgg agatgccttg attgactcaa
    75661 gtgctagaga ctatctcaaa acaaacttac tacctctagc aactattatt acgccaaatc
    75721 ttcctgaagc agaagagatt gttggttttt caatccatga ccccgaagac atgcagcgtg
    75781 ctggtcgcct gattttaaaa gaatttggtc ctcagtctgt ggttatcaaa ggcggacatc
    75841 tcaaaggtgg tgctaaagat ttcctcttta ccaagaatga acaatttgtc tgggaaagcc
    75901 cacgaattca aacctgtcac acccatggta ctggatgtac ctttgctgca gtgattactg
    75961 ctgaactagc caagggcaag agtctttacc aggcagttga taaggccaag gcctttatca
    76021 caaaagctat tcaagatgcc cctcaactcg gtcatggttc tggtccagtc aaccatacaa
    76081 cttttaaaga ttaagaaaaa aaactctcta gttcccactt taagggaatt agagagtttt
    76141 tatactcttc gaaaatctct tcaaactacg tcagcttcca tctgcaactt caaaacactg
    76201 ttttgagctg acttcgtcag tcttatctaa aacctcaagg cagtactttg agcaacctgc
    76261 gactagcttt ctagtttact ctttgatttt cattgagtat taattaggaa agaatgtcat
    76321 gcaactttgt taaaaaggct tgcgtttttg cctcaatatc ttctgcttgc atcaaatcac
    76381 gtacaacagc tacaccagct atacccgtgc cgataagttg gtcaatattc tctgatgtca
    76441 agccgccaat agcaactact ggaatggcaa ccgtttgaca aattgttttc aaggttgaaa
    76501 tcagggtgat gggtgcattt tccttggtgg ttgtcggaaa aatggctcct gtccccaagt
    76561 aatctgcacc tgatttctcc gcttccagag ctcttttaac cgttttagcg gtgacaccga
    76621 ggattttttc aggacccaag actttgcgag ctaccgaaac tggtaattca tcatctccga
    76681 tatgcagacc tgctgcatca accgcaagac aaacatccaa ccgatcatcg attatcaagg
    76741 gtacctgata agcaactgtt atttccttga cttgttttgc cagttgataa tattgattgg
    76801 ttgtgagatt tttttctcgc aattggacta tggtaacccc tgaacggcag gccgtctcaa
    76861 cttttgcaag aaagctttcc acggaatctt gatagcgatt ggttaccaga tatagtctaa
    76921 gtgcttctct attcataaac ctctcctttg atggtatcta gccaattttc atctcttctt
    76981 aggagcgaaa gctgattgag tacttggtaa cgaaattctt ccaatcccat tccttgaaca
    77041 actattttct cagcagcgat attgagataa gagactgcta agcaagaagc ttcaaaacca
    77101 gtctttcctt ggctgagaaa aacggctgtt aaggctccaa ccaaatctcc tgtccctgtt
    77161 atccagtcta attcagtaca gccattctcc agtacagcga cctgattttt cgaaacgatg
    77221 aggtccttgg ggccagtaac taagaatgac ataccaggat aggtctgaca ccagtctttc
    77281 aagacttgaa gcaaatcctc cgtttcttga tctttagcac tcgcatcgac cccaacgccg
    77341 tggtgcttta atccaacaag acttcgaatt tctgacatgt ttcctttaag gaccgtaggt
    77401 ctatagtcta aaaggtcttt aactaagctc ttacgaatgg atgaagtcgt tacgccaacc
    77461 gcatctacta ccattgggag acaaacttga gctgcataag aagctgctat acggattgct
    77521 ttctccttct cagctgacaa atgccccaaa ttgatgaaga gagcctgact ttgcttagta
    77581 aaatcaagaa cctcacgggg atcatctgcc atgacaggtt tgcatcccag agccaaaatc
    77641 ccatttgcca gcatctcaca agaaatctca ttggtcatac agtgaatgag ggaactagag
    77701 cctataggaa agggatttgt aaattcctgc atcagtctat cctttcacta aagaaatatc
    77761 cctgcacttt tttaaagaat tcctgcttga ttaaaaatcg aaaggcaata aaggaaatcg
    77821 ctgtaccaat caaggttgct ccgaaaaatc gaggcgtgta gataaaccag ctaagcttag
    77881 cagctgatcc tgtaaagagt accataacag gataggaaac aatagaacca ataatacctg
    77941 ttcccacaat ttctcccaag gcagaaaagt aaaattttcg accgtactta taaaagagac
    78001 ctgctagaag ggctccaaaa gtcgctcctg tgagagctaa aggcggaatc ccttgagtcg
    78061 tcatacggat aatggctgtc actgtagcca tagccaaggc ataaacaggt cccatcatga
    78121 ttcccgctag aatattgact acactggaca tcggtgccat tccctcaatt cgaaagatag
    78181 gtgtaaggac tacatcaagg gcaatcatca tagataaaat ggttaatttg tgaacttgta
    78241 attggtgctt tctcatgttt ctattcttct cctttttcta aagactgtaa atcgctcttc
    78301 catgtctggt gttggtaggc catttcccaa aacttggctt ccatatgaac actgatgtgg
    78361 aaggcatcta gcattttttg cttgtctgtc tcgtcacttt ctcgatagag ctgattgacc
    78421 agtgctccct cctctctgat ctgttgctct aactcatccg taatataagt ttcaatccat
    78481 tgttgataga gaggatttgg tgatggttta agattaagtg atttgcctat atcatggtat
    78541 aaccaaggac aaggaagcaa gcttgcaaaa gctatggcta agttcggttc tgcaaattgc
    78601 ctataaatat gagaaatgta atgataacag gttggagcga ttggatgttg ctccatttcc
    78661 tggtcgttga tttccaattc cttgaaaaat tgttggcgaa taaataactc accctccact
    78721 aaaccctgag cattttgttt caaaagtctt ttcatctctt ggtttgaagt cttatcagcc
    78781 aaaagatgat agatttctga gaaagccttc agatagtagg catcctgaat caggtaatag
    78841 cggaaaatgg caggttctaa attcccctct tgtaattgta aaataaaggg atgatgaaag
    78901 gaaacctgcc aagctttctt ggataattcc atcgcaatat ctgtaaattc cataataact
    78961 cctttataaa aatagactgg tttgaagcaa taaaaagaaa agcaggtaga ttaattttgt
    79021 ttttttagga atataaaaag tccgatagct attcttcaac tgtgcatgtt cgtcatatcc
    79081 gtgagcagat agagctctca ggtaaagatg gcgccaccta aagactgtca tcagaacctt
    79141 actgtaaatc aagggcgacc aaaaatgtag ttcttgacca cgtaataggc aagcttcttt
    79201 gagggacttg atttcttgct gaatgagagg aaaagaattg aataccacaa tcaaggcata
    79261 ggaccaagag cgtgatagcc ccttttgagc caagtacaag agaagctctt ttagtgaaat
    79321 agaggaaaca aagacaaggc cgatacaaac tgtcacaaag gccctcgttc caagcatgac
    79381 tgcctgtgaa gcatctccgt gtaactgaac tgcccagtag ttggcaaaag atggtaaaat
    79441 ggcaagtatg atcatccaag ctaacatttt aaatcgacgg taatagagca taaagagaac
    79501 acaaaatgcg actaccgaaa gattcagagc aatcgaagga atgaaagatg tttccaagga
    79561 taaaatcagc aagaagagac tgataatcgg tgtctgggtt gctactttga ccatactatc
    79621 tcacctcccc ttgggtattg ctactctgag atgtaagtgg tttggtaatg gtcacttctt
    79681 tcacatgccg aagaccctga ctagtcatct caatccaata atcaaccaca gaaatcaaag
    79741 ggtctaaacg atgactaatg agcagaaaac ttcttccttg attcctctcc tccacaatcc
    79801 acttgcaaaa ataatggcag gctctatcat ccaaacctgc aaaaggttca tctagcaaga
    79861 tcacggaagc cttactggtc aagatggtca agagctgaag aattttttgc tgaccaccac
    79921 ttaattgata gggactctta tcgactgcct gctccaaatc aaaatctcgt aaagcttgaa
    79981 aaatccgctg atttctttca gaatcaggtc catctaattg aagctcctct cgcagactga
    80041 ctcgaataaa ctgcttctca gcttcctgaa caacaccagt cagatcacga tacaaactct
    80101 ttttcttttt cagaaccgaa cccttccaag taatgctccc cttatacttt tgaaattgaa
    80161 gaatagagcg aaagaaggtt gatttcccga caccattgtc acccaggata caggaaatcc
    80221 cttgatagaa tgtgaaatca gcaattgaaa agagggagcg atttccaaac tcacaagtcg
    80281 ttctatccat atggaatagt tccgggctag aagcaacttc ctttgaagca acctctgtca
    80341 tctcatagga agggatttga aacacttccc ttagttttcc gtctcttagc tcaaccatat
    80401 ggtcgatata ggctttatag tcagataaat catggtcgca caaaataact gtcttcccat
    80461 caagagccaa ctcttttaga atctccaata tctcgattct gctcttgcgg tcaatggaag
    80521 cgaagggctc atccaagaga tataccctag gattcatggc aaagaggaca gccagcgctg
    80581 ctttttgctt ttccccacct gataggtgat gaatgggacg gtgtaagatt gcctcgcaac
    80641 gacattgctg gacaacctct gctattttag aatcaatttc ctgaaggtga tagccgatat
    80701 tctccaaggt gaaaatcagc tcctcaaaca agttctccat ggtaaattga tgattgggat
    80761 tttgaaagag aatgccaacc ttctggacac gtgcgatgat agaaagctga ctgacctcgc
    80821 tcccatctat caggacttga ccactatagg gaggagaact gacttgggca atgacttgaa
    80881 aaaggctgga ttttcctgaa ccactgctcc caactaacaa ggtaaaggct tgcgcatgaa
    80941 aagtaaaatc aaacggctca gggaagattg gagactgaat cgctcgtagt tccagaccca
    81001 tctatgcttt tcctccagtt gcaaactgat gatagagttt gacaatggca cgaaccaaga
    81061 tggtacagaa gaaataaaca gaaataaaac gtaccacaag taaggaaagg acaaacggaa
    81121 gggaaaaggc gtagtaacct aacttaatgt attcatagac aaagctaaca agcgtaatcc
    81181 caatactatt agcagttaga gagagccaac tttcatagcg attcttagtt acgataaaac
    81241 caaattcact tcccaaacct tgaaccaagc cagacaaaag agctcctaga ccaaattggc
    81301 taccataaag gacttcagca agcgcagcta gcacttctcc aatcgttgca cttccgactc
    81361 tcggaacaaa gatggcagca atgggcgcag ccatacacca gagaccgaag aggatttcat
    81421 tggcaaaggc ctgcaaacca agaggtgtta agagtagact gagaatatta tacacatatc
    81481 ctgaaccaac gaaaacccca ccaaaaaaga tagacaagaa agcaagcaag ataacatctt
    81541 ttaactgcca ttttttcaac ataaaaaact ccttttttta aagaaaagtg gggcactcaa
    81601 gaagaccgac ctaaatactt tgtatagcag actgaattta gaacagtaca caagaatgct
    81661 aaaatatttc tagaaattaa tttgaatttt ctaattgatt tgttcgcatc ttatttcaat
    81721 ctactatatc atcttcatcc agtttcgtaa aagaaaaaac tctaattaca gatacgaatt
    81781 agagttcagc ttacaagatt agacagttct tttcgacata cgaaaaaaac atttcacatt
    81841 tcccttcgcc agtcttaact gtatcaggtt caatgggtat catctcagcc taaagcaccc
    81901 caaatgtctt tattatttaa ttatgtgatt attataacac acattttata ctagttcaag
    81961 aaattgaact ggaaatacag ccttgcactc acaaagacag cagatctttc ttttgcaaaa
    82021 aacaaatgac ctgtttgatg aattagccat tcaagctgaa tctggacata gctttttaaa
    82081 aaaggaaaat cctacttact tagaatccaa ggatagatat ctattgttca ctcatttccc
    82141 gaacagtttt ttctatattt tttgcatacg atattgccga aatgattgaa acgccatcca
    82201 tattggtctt tataatgtct ttaatatgtt tcgtctgtat cccaccaatt gcaactaaag
    82261 gcatttgtgg caatagtttt ctcatcaatt caagaccttc ataacctata gcaccaccag
    82321 catcatcttt tgactgggta tcaaatacag gcccaacacc tacataatct acatattcaa
    82381 cttttgattg ttgaaattct tcttcgtttc ttatagaaag accaattatt ttatctggca
    82441 tcaattttct aatttcatca acaccaatat catcttgacc tacatgtacg ccatcggcgt
    82501 caatttccat tgctaaatct atatcgtcat taacgataaa tggaacattg tattttttac
    82561 aaagttcttt aatttggata gctagctcaa gtttttctaa gccttctaaa gcaccctcac
    82621 ctttttctcg aaattgaaat aaggttatac caccttttaa ggcttcctca acgactgtat
    82681 atagattttt tccttggcaa gtagtcgttc cacaaataaa atatagtttt agtaattctt
    82741 tatgaaacat cttacttcac tcttttgaat tcctttacat cttcatctgt aatctcgtat
    82801 aaggcattta taaattcaac tttaaatgtc ccaggaagat gtccatttgg acgtttttct
    82861 gccatttctc cagcgatatt gtaaactaac attgctgttt ctaatgattt taattcttga
    82921 cctttttcca gtccgataaa acttgctact acagctccta ataaacatcc agttccaata
    82981 acttttggca tcatggcact accattatga atcgttacca cttctccatt taccgcaata
    83041 gcatccactt cacctgttac tactattgga atattgaact tctcatttgc tgctagagca
    83101 atctcgtcaa tattatctac tcccgcacta tctactcctt tagatgccac atctattcct
    83161 actaaagagg caatctctcc agcattcccc ctaatcgcag ctagtttgta attgttgatt
    83221 aaatcatctg ctactttttt tctatattct cctgctccac aggctacagg atctaaaact
    83281 gctgggacat tatatttctc tgcaattttc agagcagctt ggtataattt ccaattttca
    83341 tctgtcaatg ttcctatgtt tattaataaa ccaccagcat actttaataa gtcctctaaa
    83401 tcttctggaa actcactcat ggctggtgag gcgcccagtg ctactaatcc atttgctgtg
    83461 aaatttttta ctacatcatt ggtgatgcaa atgaccaaag gtgctttttc ttttaataat
    83521 tttaaacttg tcatattgaa atccttcctt ttcactttat acgatctact aatttcgatt
    83581 tatctttagt tgagaatttt tttcatttac attgaatgat ttatactcaa tgaaaatcaa
    83641 agagcaaact aggaggctaa ccgcaggttg ctcaaaacac tgttttgagg ttgtggatag
    83701 aactgacgtg gtttgaagag attttcgaag agtcttacct catcaaattt gtaaatatca
    83761 tgagccttct ctagacatcg taaccaatat caaaaaaagc taattctaaa gcgactgctt
    83821 gattccagcg ttgctgaagt tctgtcaaat cttctcgatt tttaccgaca cgattgagtt
    83881 cgtcaaccag aaattgaacc cactctgcaa agaaaggacc tctgtggaga ttgatccatt
    83941 ccgaatgaat atagacttca ggtaaagcca aatctttaga accccagtct aaatagagac
    84001 cttctgcaat gaccagcata atcaaaagat gggcatagtc tgatgaagcc actgccgaat
    84061 acattagatc ctgaaaggct tttgttacag ggtgcaaagt cacttctaga tagtcattct
    84121 ctgctacttt taactcttta aaagcctttt ggaaataacc atcttcatct gcttcaagaa
    84181 agcctagttg cttggcaaaa cgaagcttgg attcaagttt atctgcgtga gctacgcagg
    84241 cacccagcat ggataagaag gcatcaaaga agtgataatc ttgaatcaga tagtccttta
    84301 agaccttatt ctcaattgtc cccgcaaaaa gttccttaac aaaacgatga ttgattgcag
    84361 ccttccaatc cttctgactg ctttttaata attctccaac agtcaaacct ggctgaaatg
    84421 catagtcttg tgtttccata tttacttctc ctctctttac ttgttagtaa ttaataaaac
    84481 accaagaaat atcaagcaaa atcgtaattc cacttgatcc ttttaaagca catcgagagc
    84541 atttgcagag agctaactaa acaagcctat ccagtttata taaacaaaaa actccaatta
    84601 caatcaagaa ttagagttga cttacaagat tagatcgttc atttcgtcat acgaaaaaac
    84661 gtttcacatt tcccttcgcc agtcttaact gtatcaggtt caatgggtat catctcagct
    84721 taaagcaccc caaatgtctc tattatttaa ttactgaacc agtatagcaa aaaatgaaag
    84781 ccctagcaag atatttgacc gaaaaatatc tttatatata gtagattgaa actagaatag
    84841 tacacatcta cttctaaaac attgttaaaa atcgatttaa ctgtcctgat tgatttgtcc
    84901 tgtttttatt ccattttact atggttttcg atagcgattt attcttccaa tacacgaaga
    84961 aaaacctcca cattcagtgg aggcaatctc ttttatcaat acaattttaa gtcacgaggg
    85021 tcaactggga aagttgggtt gtatgggttg tgacggagtt tgaagtgttt aacatcttca
    85081 atagtctgag ttccagacaa ctgcataact gtcttcaatt ccgcattcaa gtgttcaaag
    85141 acttgacgca caccaacact accgccgaga gccaagccat agataaccgg gcgaccaata
    85201 gctaccaagt ctgctcctga agccaaggct ttaaagacat gttgaccacg acgaacacca
    85261 gagtcaaaga caattggcac acgtttatca actgcttctg ccacttcttg aagcgagtca
    85321 aaggcagctg gtccaccgtc gatttgacga ccaccgtggt tggttaccca gataccagaa
    85381 gctcctgcag caagcgaacg ttcaacgtcc tcacggcatt gtggtccctt gacatacaca
    85441 ggaagtcctg agtattcagc gataaattct acatcacgtg gagacaagcg ttgtttagct
    85501 gatttgtaaa caaagtccat tgatttacca gcaccttctg gcaggtattc ttcaacaatc
    85561 ggcatgccaa ctgggaagac aaaaccatta cgcttatcca cttcacgatt cccccctaca
    85621 gtagcatctg ccgtcaagac aatcgcttta taaccttcag ccttcacacg atccatgatg
    85681 tggcggttga taccgtcatc cttactaaag taaaattgga accaatgggg tgtcccttga
    85741 agggcttcag aaatctctgg aaggtcaaca gtagagtaag aactggttgt ataaagagaa
    85801 ccaaactcat gcacaccacg cgcagtcgcc acttccccct gttcattcgc taatttatgg
    85861 gccgcaacag gcgccataat gattggtgaa gatagttttt cacctgcaaa ttcaatctct
    85921 gtacttggat tttcaacatc gcaaagtgta tgaggaacga tgagtttgtg gttaaaggcg
    85981 cggatattct ctcttaaagt gaaagtatct tccgccccac tagcgatata gccaaatgct
    86041 gctttaggaa taacttgttg cgccattggc tccaaatcat aggtattgat gaagtctaca
    86101 tgaccttctg cattgcttgt tttgtatgac ataaaatgcc ctccttgatt aagtaagcgt
    86161 ttgcttttta ctacacaact ataataactc ttttttcaat cattttcaag agttttgctt
    86221 aaaaaccatc ttattttttc atacaatata ctagccctac tttccttaaa ctctaaacct
    86281 tagtctatat taagtgaatc gttgagattt tttgctgcca ggcatttgaa ctactttttt
    86341 atttgcggat tctatctact aatactataa aaaaaacaag tgaataagac accagaacat
    86401 cctctaatag gacctatgga cttatatcag tcccatatat actgtttaag caagatacta
    86461 tcctagttga cgctaacttc ctatcccact tattaatttt ttatttatag tgaatctgaa
    86521 caaatcaatt ggggaatcca agtcaatttc tagtactttt tgaacagttt cagcgtacta
    86581 tcgtaaaatg aaataaaaca tgcacaaatt gcttagggaa tttaaaccaa tttctaacaa
    86641 tgtcttagaa atcaaagtgt actatttcaa cttcaatata ctacacttca ttttctcctt
    86701 aaattcagtc tctttttgaa tcaaaaaatc ccctggtaag agccagagga taagaattta
    86761 tttcattgtt gggaagagca atacatcacg gatagttgtt gtatcagtga ggagcatgca
    86821 gagacggtcg ataccgattc ccaaaccacc tgttggtggc ataccgtatt caagagcttc
    86881 aatgtagtca tagtcgattc ctgtcgcttc atcatcacca agttctttgg ctttagcttg
    86941 ggcttcaaaa cggctaagtt ggtcgattgg gtcgttcaac tcagtaaagg cattaccgta
    87001 ctccttagtc atgataaaga gctcgaaacg gtcagtaaag cgttggtctt caggattttt
    87061 cttagcgagt ggagatacag ctactggatg tccatagaca aaggttggtt ggattaaagt
    87121 ttcttcaaca aactcttcaa agaaggcatt gatgatgtga ccaacctcag tgtagtgttt
    87181 ctcaactgga actttcttct cagcagcgat agctttagct tcttccaaag tcatgtcttg
    87241 ccagaaatcg acaccagtaa tttctctgat agcatccacc atatgaacac gcttaaatgg
    87301 ttcgttaatc ttgatttcag taccttggta gttgactggg ccatcacctt tgactgattt
    87361 agcagcgtgt tggataatgc cttcagtcaa gtccatgatg tcttggaagt ctgcataagc
    87421 ttggtaaact tcgatagaag tgaactcagg gttatgagta gcgtccattc cttcgttacg
    87481 gaagatacgg ccaatttcat agacacgttc cataccaccc acgataaggc gttttaagtg
    87541 aagctcagtc gcgatacgaa gcaccatgtc aatgttttgg gcattgtggt gggtgataaa
    87601 tggacgggca gcagcaccac cggcttcatt atgaagaaca ggtgtttcca cttcaaggaa
    87661 tcctttttgg tcaaggtaac gacggatttc agagatgatt tttgaacgag tgacaaagcg
    87721 ttcaaagctt tcacgattag aaatcaagtc aaggtaacgt ttacggtaaa ttgtttcaac
    87781 gtctgtcaaa ccatggaatt tctcaggaag aggacgaaga gccttagaca agtgtgtgat
    87841 gtgggttgcc ttgatagaga gttctcccat atccgtacgc atcacttcac cttcgacacc
    87901 aaggaagtca ccaaggtctg cttttttgaa gatttcgtag ttttcttcac cgacagcatc
    87961 cttacgaacg tagatctgaa tctggccttc gcggtcttga aggtgggcaa aaccaacttt
    88021 tcctttacca cgtttggtta ccaagcgtcc tgcgatagta gctgtttcgt ttttatcgtg
    88081 taattgttct ttatcgaggt tggtatattt atcttttaat tcttgtgaat ttgcagtacg
    88141 ttcaaaacgt tttccgaaag gatcgattcc ttgttcgcgg agcgcagcca ttttttcacg
    88201 gcgaacgatc tgctggtcat ttagttcttc catatgttct gtagacatgg gatcctccta
    88261 gttttactca aaattgaata cgatgagtca ttttttgcga tactcccatt ttatcataaa
    88321 taagcaagaa attcacggat aatctttaaa aactaaaaag aacctgacgc taaaatcact
    88381 ggaaagaagt gaaagtatct cccgccccac tagcgatata gccaaatgct gctttagaaa
    88441 taacttgttg cgccattggc tccaaatcat aggtattgat gaaatctaca taaccttctg
    88501 cattgcttgt tttgtatgac ataaaatgtc ctccttaata agtaagcgtt tactttgtgt
    88561 attacaaaaa tatcttaact ctttttcaaa acttttaaaa tattttgttt ggaaatttca
    88621 gaaattttat gtctatgata aaaatcctta taacggcaat aaaaaataga tattatccaa
    88681 agaagatttt aagtgctaca ataactgtat tatttctaga tgggaggttc tatttttgga
    88741 ttgatccatt gttgaacaat atctaccact atatcaaaag gcattctttc tgaccttgca
    88801 tattgcagtt tggggaattt tgggatcctt tctgctcggt ttaatcgtta gtatcatccg
    88861 acattatcga atccttgttt tgtcgcaagt agcgacagcc tacattgaat tgtcacgtaa
    88921 tacgcccctt ttgattcaac tcttctttct ctacttcggt cttccccgaa tcgggattgt
    88981 cctatcttca gaagtctgtg caacgcttgg gcttgtcttt ttaggagact cctatatggc
    89041 agaatctttc cgaagtgggc tggaagccat cagtcaaacc cagcaggaga ttggcctcgc
    89101 tattggtctg acacctctac aggtctttta ctatgtggtt cttccgcaag caacagcggt
    89161 ggcactcccc tcctttagtg ccaatgtcat tttccttatc aaggaaacct ctgttttctc
    89221 agcagtggct ttggccgacc tcatgtacgt cgccaaggat ttgattggtc tctactatga
    89281 gacagacatt gcgctagcta tgttggtagt tgcttatctg atcatgctgc tacccatctc
    89341 actggtcttt agctggatag aaaggaggct ccgccatgca ggattcggga atccaagtac
    89401 tctttcaagg aaataatctc ctgagaatct tacagggatt gggcgttacg attgggatat
    89461 ccatcctgtc tgtcctctta tccatgatgt tcggaacagt catgggaatc atcatgacct
    89521 cccattctag aatcatacga tttttaacac gattgtatct ggaatttatc cgtatcatgc
    89581 cccagctggt gctactcttc atcgtttact ttggcttggc tcgaaacttt aatatcaata
    89641 tctcaggtga gacttcagct attatcgttt ttaccctctg gggaacagct gaaatgggag
    89701 acttggtacg tggagctatc acttctctcc ctaaacatca gtttgaaagt ggacaggcac
    89761 tcggcttgac taatgttcaa ctttactacc acatcatcat cccacaagtc ttgagaagac
    89821 tgctaccgca ggctatcaat cttgtcactc ggatgattaa aaccacttca ttagttgttt
    89881 tgattggggt tgtggaagtg accaaagttg gacaacaaat catcgatagc aatcgcctga
    89941 ccatcccaac tgcttcattt tggatttatg gaaccattct agtcttatat ttcgcagttt
    90001 gctaccctat ttccaaacta tccactcact tagaaaaaca ttggagaaac taaatgtctg
    90061 aaactatctt agaaatcaag gaactaaaaa aatccttcgg agacaatccc atcctccaag
    90121 gactttctct agaaatcaaa aaaggggaag ttgttgtcat cctagggcca tctggttgtg
    90181 ggaaaagtac cctccttcgt tgcctcaacg gcttagaaag tattcaaggt ggagatattt
    90241 ttctggatgg tcagtctatc gttgaaaata aaaaaaattt tcacctagtt cgccaaaaga
    90301 ttggcatggt ctttcaaagt tatgaactct ttccccatct ggatgtctta caaaacctca
    90361 tcctaggccc tatcaaaact caaggaaggg acaagaaaga agtaacggaa gaagctttgc
    90421 aattactaga tcgtgtcggt ttgctggata aacaacatag ctttgcccgt caattatctg
    90481 gtggacagaa gcaacgtgtt gcaattgtcc gtgccctcct aatgcatcca gaaatcatcc
    90541 tttttgacga ggtgactgct tcgctggatc cagaaatggt gcgtgaggtg ctggaactta
    90601 tcaatgattt ggcccaagaa ggccgtacca tgattttagt aacccacgaa atgcagtttg
    90661 cccaagccat tgctgaccgg attatcttcc tcgaccaagg gaaaatcgct gaagaaggaa
    90721 cagctcaagc cttctttacc aatccgcaaa ccaaacgagc ccaggaattt ttaaacgtct
    90781 ttgactttag ccaatttggc tcatatctat aaaggagatt cttatgaaac tattcaaacc
    90841 actcttaact gttttagcac ttgcctttgc ccttatcttt atcactgctt gtagctcagg
    90901 tggaaacgct ggttcatcct ctggaaaaac aactgccaaa gctcgcacta tcgatgaaat
    90961 caaaaaaagg cggtgaactg cgaatcgccg tgtttggaga taaaaaaccg tttggctacg
    91021 ttgacaatga tggttcttac caaggctacg atattgaact agggaaccaa ctagctaaag
    91081 accttggtgt caaggttaaa tacatttcag tcgatgctgc caaccgtgcg gaatacttga
    91141 tttcaaacaa ggtagatatt actcttgcta actttacagt aactgacgaa cgtaagaaac
    91201 aagttgattt tgcccttcca tatatgaaag tttctctggg tgtcgtatca cctaagactg
    91261 gtctcattac agacgtcaaa caacttgaag gtaaaacctt aattgtcaca aaaggaacga
    91321 ctgctgagac ttattttgaa aagaatcatc cagaaatcaa actccaaaaa tacgaccaat
    91381 acagtgactc ttaccaagct cttcttgacg gacgtggaga tgccttttca actgacaata
    91441 cggaagttct agcttgggcg cttgaaaata aaggatttga agtaggaatt acttccctcg
    91501 gtgatcccga taccattgcg gcagcagttc aaaaaggcaa ccaagaattg ctagacttca
    91561 tcaataaaga tattgaaaaa ttaggcaagg aaaacttctt ccacaaggcc tatgaaaaaa
    91621 cacttcaccc aacctacggt gacgctgcta aagcagatga cctggttgtt gaaggtggcc
    91681 attaactctt aaaagggact ggattttaag ctccaatccc tttttaagat tttacctata
    91741 acatcctgag tctatctaag atgttcaatc tgaacacagt gtacatactt tatcttctat
    91801 tgcatatact ttatcacata agatacgaat atcctcttca ctatgactag caatcaaaat
    91861 tgttgtccct ttttcactag agagctttct aaacaatgtt ctcatatttt ctacacttga
    91921 tttatccaag gcattcatag gttcatctag taaaagaata gagggattct ccataattgc
    91981 ttgagcaatc cctagctttt tcctcatacc tagcgaataa gttttaactt tctggtcttt
    92041 ttgctcatat agaccaacta ttttcagtgt atcattgatt tcctgattac caactactcc
    92101 tcgtatgctt gccaaatatt gtaaattctt aaagccacta taataattta taaaaccagg
    92161 ttcttcaatc aaagctccca aattagctgg aatttttctc tcaggaacaa tattttcccc
    92221 attgattaac acttctccat aagacggact atataaacca gctattaatt taaacaatac
    92281 acttttccct gagccattcg caccagtaat tcctataatt tccccctgtt tacaactaaa
    92341 attaaggttt tgaaaaacac atgttttttt taatttcaac tcaatatttt ttaatatgat
    92401 tatttcattc attctataaa cctcctcttt tgacgagtga aatagaaaat acttttaaaa
    92461 agaaagacta aaaatagcaa ctgaagaaat aaatctcgtc ctatatctcc attccctcga
    92521 ttcaaaatat aaaatagata attagttcga tttcctacaa atagaccacc aaacacaatc
    92581 atgagtaaaa agaaactaac gcaagcaaag ttcatttgta cattcgctcc tagtgcgtat
    92641 aacataaagc aaaacaagac taacacacaa gcattcaaag aatcaactat aaacaaaact
    92701 cctatatccc agtttggtaa ctgtaacata aattgaatca ctagaacttt taccatgatt
    92761 aaaatgagtc cataaagaaa acaggtccaa atctgatacc taatccagag cttaatagaa
    92821 gaaaatcgaa tcacttccat aaagaaatcg gatgctcttc tacgatatac aactgctaga
    92881 aaaaatgtat gaataataaa ccaatgaagc aaccatatag ataagactaa aaaagagttt
    92941 tgactcagat taggcccttt taaaatttct ataacaagtc tatcatttcc ttctaaccaa
    93001 taccataatc ctaaacaaat caatatccaa aaaagaacat aaccccaaaa gtacttggta
    93061 tagattatct gattcaacct ccacatgtga ctacttaact ttcccatttc caacttttac
    93121 actctcctcc agtttctatg aacagaaaat acagtcaatg gaattatgat agatagtaat
    93181 gtaagccaat aaatcaatgc atacggattg gaatttacca tatactgaaa aattggcaat
    93241 aatccaatta tcccattgtc caactgataa atccagaata aggattctac aaataaaaaa
    93301 gtaaacagaa atactaagct catgtttgat tttttaaacc aagaaaaact gctaatagta
    93361 agtaaggata aaaagaaata gtatgctata taagagaaaa aaaatcctat aaagaaacta
    93421 gcattgtttg caatacttat accataaaat tctcttaaaa aatcaacctc ctttatctcc
    93481 aaagagaagc taaaaccatt actaaatgca attagaaaaa tcaataaaaa taaagtcgcc
    93541 gtccaaatcc ccgtactaag agctgctaat ttgaaactaa aactggtaaa gtgcttaatt
    93601 gatttcagac gaatgcgaca ctccaaccta ttaaaatagt tattcatcaa ataaaaaaag
    93661 aacaatatat atgtgaacgg aaagcaatat actccagtcg tcatatcttg aagtaaaact
    93721 aagatccatt ctaatacatt tggatggatt gaatattggc gacagcgcaa taaatatact
    93781 gtactagata aaacacagga tagcagtaat ataaaataaa ccaatactga taaaaaatct
    93841 tttttgtaaa attgaacaaa ttgtttcatt atacgtagtc ctctgaatgt agaaaaaatg
    93901 taccataaac aaccaaacaa ctaacaaata aaataaaagc aagatgccca ctaactaagg
    93961 aaagactgat atctttctga tatcccaaag ctaatgttgt cacaggttct aagtaagata
    94021 gccctaaaat agcccaaaaa ataccaccaa ccatcatata ggcaactggg atgaaaatag
    94081 ctcctatttt tttcttcact agcaaagcac tagctagtcc aaaaatagag aacacagcgc
    94141 cccaaactcc ataccagaga gtcgttacaa gactatagag aaactgattg gaatcaaata
    94201 attcttttaa ggcaccacta taatctccaa tataaatttc ctgataagga gtcactaaaa
    94261 gattaattcc taataataat aaatagggga gaaaaaagac tagaaaagaa gaaataatta
    94321 cagtactacc cacaatagcc agatacttct ttttagaaat tcgacacaat tgtgctgtta
    94381 gaaaatgact ctcagcatcc tctattatct gactagaata gggcagtgta cagataagtg
    94441 cagctactag gctaatcggt gaaaatcctc gaatagaaga agcggcaaaa aaaatcgata
    94501 aaccttcaat tttataaata ccattgaaag caaggaaatt tcctaaactc atgcaaagaa
    94561 gggtcaaaaa taaagacata taaaatcgag gtgattgaac gactcgtaca agattacaaa
    94621 tgaaaaattc catccttact cctccttata ataaaaatag ggtgtagcat tcttttttca
    94681 tgctacaccc acaatcaacc atctctaagg cttactctga caagtaagtt aataagaatc
    94741 tggattccaa gaacctgaag tatgaattct tacatgattt ccaaattgtg gcgccatagc
    94801 taatctagta ccagaaccaa tataattgtc accacctcca ttatagtaca tgacaatcct
    94861 agagccagac cccaatgaat ataccggggt aatatctgac ccactatagg cgctacgaat
    94921 agaggtattt aaccttttac cgccaccagt gctgtcatta ttattaattc cagcagaggc
    94981 gttttctttc tcaagctcac tagttgtatc cgaaccccaa cgcggcaacg ttaaatcata
    95041 atctccaatc tgtctagcta aaactgtaag gagaaacaaa ctagatgcaa ttgtaactac
    95101 gcaaaaaagg aatatatttt tcttcttttc atgacatcgt cctcctaaga agtgataaac
    95161 aagatagttg attgatcaat ttgatacata ttacattttc attatatcaa caaaagaaag
    95221 cgttgtcaat cattttattt aaaatattgt catattttaa ataaaatgat aaaagaggct
    95281 cggtagcctc atctctcttt atcttactga cctaaccttc ttgccaattt tcttggtctt
    95341 ctttaaagcg ttttagaaga tcaaggccct ctggcgtgat gtaaccttct tcttgggcta
    95401 gatggataag ctcgctatag tttgaaagcg tcacaagttt aacaccagca tctgcaaagt
    95461 tcttatctgc ttttggcaat tggtagctga aaatcgctac aactccaagc acatctgctc
    95521 cttctcgctt ggctgctgct acagcttcaa gaactgaacc acccgttgaa ataaggtctt
    95581 caaccactac cattttttga ccttgagcta cgcgaccttc gatttgatta ccagctccgt
    95641 ggtcttttgg tttgctacgg atgtaggcaa aaggcaagtc catcttatca gcaataatgg
    95701 ctccgtgtgg aatccctgct gttgcagttc ctgcaatcac ttctacttca ggaaaggctt
    95761 ctttgatagc ttccacaaaa ccattttcaa ttagggtacg agtttctgga taggctagtg
    95821 tcacacgatt atcagtgtaa atcggtgact tgataccaga tgcccaagtg aagggttcct
    95881 ctggtttgag gtaaacggct tggattttca agaggtggct agcgatatct ttagcaagtg
    95941 tcatggtatt ctccttttat ttttctaatc tagttcttta attccagtcc tgtgtccatt
    96001 catccttgat ggtatgataa gctgcaacag gatcctcagc ttgggtaatg ggacgtccca
    96061 ctacgatata gtcactgccg atttgatagg catcagcagg tgtcatgact cgtttttgat
    96121 ctccaactgc agcaccagct ggacgaatcc ctggtgtcag acagataaaa tctggattgg
    96181 tagcctgctt gatgacttgt acttcctgag ccgagcaaac aacaccatcc aagccagctt
    96241 cagctgtctt cttggcatag tgaatcacag actcttgcag actggtttgg atattttgaa
    96301 actcctgcat ctgagcttct gacgttgatg tgagctgagt tacagcgatc aatttagctt
    96361 gactcccaag gccttcacgc gccgccttca tcatctctac accaccagcc gcatggacat
    96421 tagtcatatc gacaccaagc tgagacaaga ccttcatggc tgacttgact gtattaggaa
    96481 tgtcatgaag tttgagatcc aaaaagacac tatgacccaa accttttaag taggacacaa
    96541 tctcaggccc cgctgcgtaa taaagctcca tccctacctt gagataaagg ctttcttctg
    96601 ctgggaaaag agctaaaaat tccttgaccg cctcaaaact aggaaaatca agagcaatga
    96661 ctggacgatg ttctcgcata ggtttctcct tttaccttta ctagtgagag agtctggcca
    96721 acagaagcca cgaaaaaagg aacctgccaa cagcaaggtt ccacgaaaaa tgggtagtct
    96781 ccaccctttc accgtctaac cttagctgcc tctctggact gctttaaagg ttttttacta
    96841 ttctattatt tctactagca cttgtcaagt aaaaacatgg tcactaaaga actataagag
    96901 aaaaggtaaa cctagcgacg cgatgagcgc tgggtcgttt ggtttcgatt gctctcttcc
    96961 tcttgttttt tctgttcttc ttcttgtttt ttctcagctt ccttagcctc ttgtttggct
    97021 ttttcctcag cttccataat taatttatcc gccacagtgt aactgtaaat tccagcttcc
    97081 atgtcaatca cactcggttc tgacaattgt ggcttaatct tactataata aggcagtttc
    97141 ttgctcattt cagaaagcgg aaccaagact tcgtccaaat cattcatagt caatcgaatt
    97201 aaatcggatg tcaccttgct tggggctaat tccacctttt ggatagccgc cttgagttct
    97261 gggctaattt gagcaagttc tgagacaaaa accttgattt gttcactatc attaaagaga
    97321 actgataaat aagtttctgg taaactgttc aggctcacag aactagtctc aagctgacca
    97381 ctggaaagaa taggataatg attttcacca gaaatatagt aggccacaat atcatattcc
    97441 ttgaccttaa tagtgaactt agttggaaat tgatagacaa gttgagctga ttcaacccaa
    97501 tagttagact taatctgctt ttcatatttt gccttgtcta gcagaaggtt aatcgtataa
    97561 tccgaatcct gaatgcctga agcctgtcga atatcatcag ctgtagtttg caccgttccc
    97621 tcaacacgaa tatctttcat ggtcgcataa ggactgagca agtaggcaga gacaatcaat
    97681 aaaagcagac ttggaaataa aatcgtgaag gctcgcaaga tatggatacc aggaatcttt
    97741 gctttggctg gtttttcctt tgtagccttt ttagcaagct ttttatcctg ttcctccttc
    97801 tctttagact ctggttcttc tttctcttct ttctctttgt catcctctga ggatgctact
    97861 ttttcttcag actcttcctt agctgattct gaatcttcct ggtctgtttc actctcctgg
    97921 tcctgtttgt cctctgactt ctcagattct tctcccatcc gagcttgtct ttccttttcc
    97981 ttctcctcag ctagagccgc ttcttcttca gccttctttt ttagatattc ttggtttcgt
    98041 ttctgccatt ctgataactc tttcaattct tcgaggattt ctttgtcctc atttttctta
    98101 tcttttgaca tttactttcc ttatgataaa tcttttttca acaattgata aaaatctgct
    98161 agagatttca attccttaga agctttcatc ttagcttggt aatcttcctt gtgacttagt
    98221 aagtgagaaa gcttctcttc caaactatcc aaggtcaaat cgctttcttg aaggtcttct
    98281 gcatagcctt tttttacaaa gtaagctgca ttttcaatct ggtcaccacg actagcttca
    98341 cgaccaagcg gcacaatgac atgcaatttt gctatcgcca agagctcaaa aatcgtattg
    98401 gcaccacctc gtgtcacaac aatatcagcc aattccaaca agggttgata gagatcggtc
    98461 acatagtcaa cacgaaaaag attttggctc aactcattca ggctagaatc tccagttaga
    98521 ttgataatat tgtagcgctc tgttagttct ttcttatggt ctgtcaccaa ttggttaaag
    98581 acacgagcac ctgcagaacc gccaacaaac aatacagtcg gcaatttatg attaaagtgg
    98641 gtttgaatat ccaccaattc atctggttct ggattttttt gatctgaaac cttggtcact
    98701 gctcccacat gctcaacctt agacaaactc gaagcttgct caaaggttga atacatctta
    98761 gtcgcaaatt tataggcgat tttattggcc aagcccatag acaggtcaga ttcgtgaata
    98821 aagacaggca ctcctgacac acgcgctgcg ataacaggcg gtactgagac aaagcccccc
    98881 tttgaaaaaa gggtctgtgg acgaagtcgc aacatgataa agagcgattg gacgattccc
    98941 cagccaactt tgaagacgtc cagcatattt tgccaagaga aatagcgacg caatttccca
    99001 gtcgcaatgg agtggaaagt gacatccaaa cctgacttaa ggatttcttg gtgttcgata
    99061 ccacgcttgt ccccgatata gtggacttcc caaccatctt cgatgaactt gggcattaac
    99121 aaaagattga gggtaacgtg tccaaccgtc cccccacctg taaagacaat ttttttcata
    99181 ttttattctt ttaactccgc tactgtgtcg ataaagaggt cgccacgtac ttcaaagtta
    99241 gcatacatat cccagctggc attggcagga ctaagaagaa ccacatctcc ttgagtcgca
    99301 agctcatagg ccttgcgggt cgcatctgca atatctgtcg cctccacata agcgacacca
    99361 gccttgtctg ctgcccgttt gacacgttct gcagattgac ccaggatgac catcttcttg
    99421 agtccagtaa tgtctggcac caattcgtca aactcattgc cacggtccaa accacctgca
    99481 atcaagacga ccttgctgtt gtcaaatcct gataaggctt tttgagtagc caagatatta
    99541 gttgatttac tgtcgttata gaatttaaca cccttgatgt catccacaaa ctggagacgg
    99601 tgtttgacac caccgaaggc tgaaagagtt tccttgatgg tttgattgtc cacatcacga
    99661 agcttggcta cagcaatagt cgcaagggca ttttccacat tgtggctacc tggaacaccg
    99721 atttcattcg ctgccatgac tacttcacca cggaagtaga gttgaccatc ttccagataa
    99781 gctccatcaa ccttttcaag tgttgaaaat ggtacaacag tggcttctgt cttggaagcc
    99841 aagtctttta ccaagtcttg attaaagttc aagacaagga aatcagctgc tgtcatcttg
    99901 ttctggatat tccacttggc tgctacatat tcctcaaata atccatgata atcgatatga
    99961 gttggcatga ggttggtaat aaccgcaatc tctggatgga attcttgaac acccatgagt
   100021 tggaaagaag aaagttccat aacaagcgtg tccttatctg atgctatttg agcaacctga
   100081 ctggcaggat agccgatatt ccctgataaa agaccatgtt gcccagcagc agtcaaaact
   100141 tccccaatca tagtcgttgt ggttgtctta ccgttcgatc ctgtgatacc aataatcggt
   100201 gcttctgaaa tcaaataagc caattccacc tcagtcaaga ctggaattcc cttggccaaa
   100261 gccttttcaa tcatgggatt gctgtagggg atacctggat tttttaccat gagggcaaac
   100321 tcttcatcca agagttccaa aggatggcca cctgtaatga ccttgatccc ttcttccagc
   100381 aaacattggg cagctggatt gtcctcgaat ggtttcccat catttactgt cacaatggca
   100441 cctaacttgt ccaacaaacg agccgcagat tcaccagact tggccaaacc taaaacaaga
   100501 actttcttat ttttaaattg atctattact ttcatgtctc gaactccatt tctactccta
   100561 ctattttacc atttttatgg aaataaaaaa gccacaaagt gtgtttgtga ctctttcttc
   100621 taactgaatc ttaccatatc atctatgtga taaatcggta actcgaatga cctgatccac
   100681 ttgctcccaa atcagaggat tgtgggtcgc aataataatg gtccgattcg gattttttaa
   100741 agattctagg atggaaagta attcctcaga atttttgggg tctaaggaag cggttggttc
   100801 atctgcaaga atcaaaggcg gatcctttaa aattatcttc gctagtgcaa cacgttgtgc
   100861 ttctcctcct gataactcaa atataggttg cttcaaatcc aaataagaga ggtttacaca
   100921 gtttagagct tgtttcatca aagagatttt ctctttttcc ttcaactttt taccaactaa
   100981 acccagattg agattctctt tgacggtttg gctttcaatt aagccaaaat cttgaaataa
   101041 gtatcctaag taatctctaa agaaaacaga aggcttgatg tccttaagag aagtgccatc
   101101 atagatgatt tgccctttgt catatggctc caatcgtcca atcatattca agagtgttgt
   101161 cttaccacag ccacttgtac cgattaaggc ataaattttc ccaccttcaa aatgaagatt
   101221 cgtatctgaa aatagctgac ggcttccaaa ttttttagat atattcttta gttcaatcat
   101281 cctattttcc tttcataatt gtcatagaaa cacgagattc tttctgcgct tgacggtaaa
   101341 gcgtcaaaac tgcactagct agaaagacca ataaagtgag caagccaatc accaagtctc
   101401 gactgcttaa aataaagaga ctagcaccaa atacaaaact ggcaaattgg ctaaccatat
   101461 actgagcatg tgtttcaaaa aatcgtaaac ctgaaattcg tttaatcaag atatctcggc
   101521 ggaattgctc gaaatataga agattgacag aataaaatag taataaggaa ctagctatcc
   101581 ccacaatagc tcctaagatt aaagttgctg tttcagtttg aacttcatta taacgagtta
   101641 gataaacact tcttccttct ttaagatagg atacttgctc ataaattcca gctttcttca
   101701 agagttctag cccactctca tatcctttga taaagagttg ttttccagca ttgatagacc
   101761 aactagataa ggatataaaa ctatcacctg tagaagtcgg cgtgaatacc actaaaatcg
   101821 gatcagtcaa atactgagta gatacgggat tctcaccgtt attataaaca aaccgctttt
   101881 ctcccattga aagataacta acgtgcgctt tcatctcata atccaaagga gcacttgcct
   101941 cctcaccaga ttttccataa taactcaatc tttcttcaaa aactttctta agttctgctt
   102001 ctcgagagcg caaatgttct gggagcaaga ggataaactc acctttttgg agatgggcta
   102061 acttctgttt ggtctcagca tctaccacga ccttttcctt gtccaaataa ctgggactaa
   102121 catagagcgt attagcatct ggactatagg tatccagtgt ctctccctgt tcattttttc
   102181 cttgtggatt ggcaaaatgg agcagattat cctttacata aagagcttgt tcctcttcga
   102241 ttgcttcctt ggcaaaggca taccacttgc tctgattttc tgtatctttt cctctatcac
   102301 ctaagccaaa agaaatttga taatagtctg ctctatcctg ccatgcttgt tttgaaattt
   102361 caagttcttt caatcgttgg taagacgtca aacctgtctt aacagcgtat cctactgtaa
   102421 agacagcaac caactgacac aatagggtta aaatcatcag gcgtttaagg ggtaatctcc
   102481 ccttaataac gggaactaat gctttgtaac tcaaactcat tagataaaga agcattagta
   102541 aaattgaaat cgccaataaa aacaacagat agaaactaat cccaaaacca taggtggcta
   102601 acaagatagg ataaaacaaa ccttgactaa aaagaacgac tcccccacct aggaaggaaa
   102661 ggagggctga tagaaggagc tatttgatat cagtagataa agaatgcccc atgatggata
   102721 agagagtctg accagaaaag agttttatac ctgctgctct catttcctta atccgagtga
   102781 taatcactaa agcaaagaaa gataagccaa atattgctaa actaattaaa ataaggggat
   102841 ttagtaatat tcgaaaagca agaaaatagg gcggtatctt tcggtcagca cttgctttat
   102901 aacccaaatc tcctaattta tcggcaagct tttctttcgt caaggagcct gacaaaagga
   102961 gataactatt tagcggatca ctacgttcac gactttcttg gctagcttct tggaattctt
   103021 ttggtaaagt tccctgacca taagttgcat aagtaaagtg agtcgtccca tccttactcg
   103081 gctctacaat tcttctagct attaaactct gttctgagtt tgcaaaattc tccaattcct
   103141 gttcaaatac ctcacgcgtc ggttcctgag tatctttttt gacacgaagt aaagaaacgg
   103201 aatcatagct tgcatataaa tattgtggcg cacgtaagac aataatccaa gcaaggaaga
   103261 agctgagaaa aaaagttgat aataatatga atagtttctt catagtagac tccttggtag
   103321 actccttgta aacaaaattc cccctgtaat ttcttacaag gggaacgatt taaatcaatg
   103381 aacgattagt cataatcaca gtaaaatgct acttgttctc cccatttagt ccaaatccat
   103441 gcataggagg tttttccagc aggagcttct cctttatcag aatgaccatc ccatctgctc
   103501 acgatggatg aataatgata ttttttacca tgatagtaat ttgaaaaagc ctaaccacct
   103561 cctgaacctt ctccatatgt ccatactcct ccatctggat attatacagc agctgatgca
   103621 gctcccaata atgtaaaact tgaaataaga gctagagcaa gtaatctatg ttttttcgtt
   103681 ttcattttat tttttctttc aaaaaaatca caccttgagc aacaatgcaa caaaataaat
   103741 cctcctctct cttttattga aaccgctttc ttatgtgata agaataacat ttttattatt
   103801 tgttgtcaag gaaaaaatcg aattttttag atattttact atattacctc tatgaataat
   103861 attatatagt agttttattt caaaataata tgcaaccagt actaaccaaa tataaaatag
   103921 attccattaa cgaattttat tcaagttttt cccattcata ttatccaaac aaaagagatg
   103981 gtgataactc aaaaataaat tgcaatcttg taaaattcct agcaaaaaag agagccaaaa
   104041 ctctcttttt tatcttcttt tacttttttt gactggcatg agtgtaatgt ctctaacact
   104101 aaagtaagct aggagcaaca tggctattgc taggaatatt tctgttggta attgaaaaat
   104161 tttcagaaaa gatagaacca ataaaatcaa gagtgccact aaaatacata ccatagcgac
   104221 gatattgact gtccctttaa tgctttctgg tgtcgcaaat acatagagta ggagcagtaa
   104281 aattcctagg actaaataga ccatctttct ctctttctag ctcttattca gctgattttt
   104341 tcttcttgtt agctttctca cgctctgctt tgttaaggat ttgtttacgc aaacggatag
   104401 actcaggcgt tacttccatg tactcatcgt cgttcaagaa ctcaagagac tcttcaagtg
   104461 tcaagatacg aggcgtcttg ataacagctg tttggtcctt agtagctgaa cgaacgttgg
   104521 tcatttgttt tgccttcgtg atgttaactg tcaagtcatt ttcacgagag ttttcaccga
   104581 tgatcattcc ttcataaacc tcagtacctg ggttgacaaa gatcgtacca cgttcttcga
   104641 tagacatgat tgagtaagtt gtagccttac cagcatcgat agaaacaagg gcaccacggt
   104701 gacgtccacc aatttcccct ggaatcaatg gcaagtattg gtcgaaggta tggttcatga
   104761 taccgtaacc acgagtcatt gacaagaact cagttgagta tccaatcaaa ccacgcgctg
   104821 gaacaaggaa gaccaaacga gtttgaccat taccagttga aatcatatcc aacatttcac
   104881 ctttacgttc agaaaggctt tggataacag acccttggta ttcttctgga gtgtcgattt
   104941 gtacacgttc aaatggttca catttaacac cgtcgatttc ttttacgata acttctggac
   105001 gagatacttg aagttcatag ccctcacgac gcattgtttc gataaggatt gacaagtgca
   105061 attctccacg tcctgaaaca gtccatttat ctggtgaatc agttgggtca acacgaaggg
   105121 aaacgtctgt ttgcaattct gcctgcaagc gttcttccac cttacgagaa gttacccatt
   105181 taccttcttt accagcaaat ggtgagttgt tgaccaagaa agtcatttga agagttggct
   105241 catcgatgtg taggattgga agagcttcta ctgcatctgt cggagtgatg gtttcaccga
   105301 caaagatgtc ttccatacct gaaacggcaa tcaagtcacc cgctttggct tcttggattt
   105361 cacgacgttc caaaccaaag aaaccgaaga gttttgtaac acggaagttt ttagttgtac
   105421 cgtcaagttt agaaagggta acttggtccc caaccttaac tgtaccacgg aagacacgac
   105481 cgataccgat acgtccaacg aagtcattgt agtccaaaag tgacacttgg aactgcaaag
   105541 gctcatctga gttatctact ggagctggga tatggtcgat aatcgtgtca aagattggtg
   105601 ccatagtcgc ttcttggtca gctggatcat ctgacaatga agaagttccg ttgatcgctg
   105661 aagcataaac cactgggaaa tcaagctggt cgtcatctgc accaagctcg atgaaaagtt
   105721 ccaagacttc atccactact tctgctggac gagctgatgg cttatcgatt ttgttaacaa
   105781 ccacgattgg gacaaggtct tgttccaagg cttttttcaa tacgaaacga gtttgtggca
   105841 tggttccttc ataggcatct acgaccaaga caacaccgtc aaccattttc atgatacgct
   105901 caacttctcc accgaagtcc gcgtgtcctg gtgtgtccat aatgttgata cgagttccgt
   105961 tgtaagcaac ggcagtattt ttagcaagga tggtgattcc acgctctttt tcgatatcgt
   106021 ttgagtccat agcacgctct gccaattcag tacgtgcatc aagcgtttct gattgtttca
   106081 ataattcgtc aaccagggtt gttttaccgt ggtcaacgtg ggcgataatc gcaatgttac
   106141 ggatatcttc tcttaatttt gtcatgattt cctctataat attcaaaatt tattttctaa
   106201 ctgaacgatt ataccataat ttcaaataaa taacataact caagcaagtg taaatgtttt
   106261 cactccgctt ttcttttcac gtcaagcctt ttcaaagcaa gcgacttatg ataagatagg
   106321 cacagtatgc gtttagataa tttattagcc caagaaaaaa tcagccgaaa ggccatgaag
   106381 caagcactcc tcagagggaa aattctagtc aatggttgcc cagcccgctc cctagctcaa
   106441 aatatcgata caggactaca agaactcctt tttcaggatc gaatcattca aggctatgaa
   106501 cacacctatc ttatgcttca taaacctgct ggtgtcgtta cagccaacaa agacaaggaa
   106561 cttccgaccg tcatggacct gcttccatct gacatccagt ctgacaagct ctatgccgtt
   106621 ggccgactgg accgagatac aacgggactc ctcctcttga ccgataacgg tcccttgggc
   106681 ttccaactcc tccatcccca atatcatgtc gataagactt atcaagttga ggttaatgga
   106741 cttctaacac ctgaccatat ccaagccttt caaaagggaa ttgtcttttt agatggtact
   106801 gtctgtaaac ccgcaaaact agagattcta tctgcaagtc cctccatcag tcaagcctct
   106861 atcaccattt cagaaggaaa atttcatcaa atcaagaaaa tgttcctctc ggttggtgtt
   106921 aaggtgacta tcctcaagag aatccaattt ggggacttca cattgaaccc agatttagca
   106981 gaaagtaact accgcccttt gaaccaaaaa gagttacaaa tcattaaaaa ctatttagag
   107041 atgagtcgat aaaacaaaaa aagctttaaa actaaagctt ttttctttta tttaccgaaa
   107101 aattaaggcg attgctacaa tccagttaac tacagaaatc acaattccta agatattaag
   107161 aatcttttct attttatagt ctaattatga ctctttttgg tatgaaatag ccaagaccaa
   107221 tcctatgata cccaaaatca ggcctacaat tggaaataac aaaccaagaa taatcgacaa
   107281 gatacccaca aaaagtggat ttttcttctt ttcttttatg ttctaagaac tccttaaatt
   107341 ttatacaaat taattatact ataaaacaat agcttcatcc tatcattcga ctaatttgga
   107401 aataaggtta gctagtcttc actttccctt tccaagaatc caagccataa gaaaggatat
   107461 aaatctcaga aaaaccttgt tttttcaagt aaagagctgc atttgtaact cgttgcgcac
   107521 gttggttctc gtagagaagg acaggtttat ctttacgaag ggctgcaaga ctagttttca
   107581 actgacttga aggaatattg cgtgcaccaa ggatatgttt tctgtggaat tctgctgggt
   107641 cgcgcaaatc aatcaattga cccgtacgaa tcaaggcttc aaactcctca ttgtccacaa
   107701 ttttagccgc acggcgaata cgaagatagt taaagcccat ccacgccaac attgctagta
   107761 taagtgccca caaaatccaa gtaaccatta gttcttttct ccatttttct caatataatc
   107821 caattctacc ttgtgctctc tgcgaagaac tgcttctgcc tctagatagt ctaatttatc
   107881 catcaaccct gcatcgtaaa tccgagatag ttccaacttc atcagttcaa tatcatataa
   107941 gcgttttccc atgtaaacaa taataccaaa tcgtttgagg aattgctgca catcatagaa
   108001 tgttttcata agactcattc tagcaaaatt ttgtgttttt ttcaagaaga gactcacaca
   108061 atgctcctta ttttcctatc ttctttagcg attctaaggc aagtatggta caataaaaac
   108121 atgagaattc aacaattaca ttatattatc aaaatcgtcg aaactggctc catgaatgag
   108181 gcagccaagc aactctttat cactcagcca agtctctcca atgcagtgcg agatttggaa
   108241 aatgaaatgg gcattgagat ctttatccgc aatcccaagg gaatcacctt gacccgtgat
   108301 gggatggagt ttctctctta tgcccgtcag gttgtcgagc agacccagct tctggaggaa
   108361 cgctataaaa atcctgtcgc ccaccgcgaa ctatttagcg tttcgtctca acactatgcc
   108421 tttgtggtca atgcctttgt ctctttgctc aagaaaagcg atatggagaa atacgaactc
   108481 ttccttcgtg aaactcggac ttgggagatt atcgacgacg tcaagaactt ccgcagtgag
   108541 gtcggggtcc tcttcttaaa cagttacaac cgtgatgttt taaccaagat gctggatgac
   108601 aatcacctgc tagcccacca tctcttcaca gcgcaaccac atatctttgt cagcaagacc
   108661 aaccctctgg caaagaaaga caaggtgaaa ctgtctgatt tggagaattt cccttacctc
   108721 agctatgacc aagggacgca caactccttc tacttttcag aagagattct ttctcaagaa
   108781 caccacaaga aatccattgt ggtcagtgac cgtgccaccc tctttaatct cttgattggt
   108841 ttggatggtt ataccattgc gacagggatt ttgaacagca acctaaacgg agacaatatc
   108901 gtttctatcc cactggatat tgatgacccg atcgagctgg tctatatcca gcatgagaaa
   108961 accagcctat ctaagatggg cgaacgcttt atagactatc tcctagaaga agttcagttt
   109021 gatagttgag aaatgataag aaccaatatg taggctagca acaacctgca cattggttct
   109081 ttttacttat aattaaaagt ttcccctgcc aacttatcag ctagcttagg aaagagggta
   109141 taaaacttat gagctaggtt caacaaaatc gggagattga gttctcgttt gttttttcct
   109201 ataatcttga caatcttttt agccactgca tctggttcta gcaggaagcg gtcaaccgat
   109261 ttaagataag ttccatctgg gtcggcttgg tcgaaaaatc ctgttcggat tggacctgga
   109321 ttgactgttg tcacatagac tccatagggc ataagttcga gtcgcagagc atttgaaaaa
   109381 ccaatagccg caaacttggt cgctgagtaa agactagact tgccagtagc tattagacct
   109441 gccatgctga cgatgttgat gatatgccct ttgctgcttt ccttcatacg agccgcaagg
   109501 tgacgagaca gattcatcag ggcaaaggta ttgacctcaa acatctggtg aatatcttta
   109561 tcagcaatct ggtcaaatcc ctcaaaaatc ccgtaaccag cgttgttaat caagacatca
   109621 atcttgccat agcggagata aagatcagtt accagagctt ctagggctga atcgtcggta
   109681 atatcaattt caatcaattc tgcatgggaa taatttccgt agagttgggc taatttttcc
   109741 ttatttctac caagcaagat gagttggtca ttgggcagga gtttgaccat ttcttgagct
   109801 agaccaccgc tagctccggt aatgagaata gtaggcatac ttatcctttc tgtgactgct
   109861 agatttccac ttcttccaag tctttgacca catggacatt ttcaaaaatt gtggcagcgt
   109921 ctttcttgag tttgctaata tcttttgaga ggaaacgggc actgatatgg ttgagtagga
   109981 ggcgtttggc acctgcttct accgctactt gtgcagcttg catattagtt gagtgaccat
   110041 ggttacgagc aattttttca tcacccttgc cataagtgga ctcatgaact aggacatctg
   110101 cattgacagc cagacgcaca ctggcacccg tttttcgagt gtctcctaaa atagtgataa
   110161 tcttacctgg acgtggcgct gagatatagt ctgctgcctt gatttcagtt ccgtcttcca
   110221 aaacaagatc ctggccgttt ttgattttac caaaaagcgg gccgaacgga acaccagcag
   110281 ccttgagttt ttcagcatcc agcgtccctt ctagatcctt ttgcatgaca cgatagccaa
   110341 cacagaaaat agtgtggtcc agctcctctg catacacagt gaatttatcg gtttcaagaa
   110401 ttttacccag agaatcttgg tcaaactcat ggaaatgaat gcggtagggc agacgagaac
   110461 ctgacacacg aaggctggtt aagacaaatg acttgattcc ttgaggtccg tagatttcca
   110521 aatctgtctg ctcttcattg gcctgaaagg cacggctaga aaggaaacct ggcaaaccaa
   110581 aaatgtggtc tccatgcaga tgggtaataa agattttgct gaccttacgt ggtcgaattg
   110641 tggtttccag aatgcgattt tgcgtacctt ctccacagtc aaagagccaa acttcgttaa
   110701 tctcatccaa aagtttcagg gcgagacttg aaacgttgcg ggctttagag ggctgaccag
   110761 cccccgttcc taaaaattga atatccattc gatactttct aattaatcaa tatataacat
   110821 ggctgtgcgg ttttccgatc ggaaatagcg tttgccagaa aaagcagcag cttcttgcaa
   110881 taaatcctct tggctgtagc ctttgagacg ttttcgacca tcagccaatc tttccaaatc
   110941 agtcaaagct gtgagacttt ctaggctgat aacttcctcg tcctcgacag gcttcatgta
   111001 aatcttacca gactcttcaa agactaattg atgggggaaa atttgcgcaa tttcaaagag
   111061 caagtcatcc gagattttct cctcattttc aaagaaaatc cgaccaaggc cgtcactctc
   111121 ataacaaaaa ccaaaggatt taccagacag attaagccga ataaaaggct tattttctag
   111181 ggtgaaactt ggctcagtat tgtaaagatt cagttcctga ctgagttctg caaaataatc
   111241 cgtcgcagcc tgaggactct ttttctgata gagttctgca aagtaggcat taacaacact
   111301 tggcggaggt gtaataagtg ttaactgctc ctgatctgtt ttaccagcta gaagctgatc
   111361 cagatagacc ttgtccagac ttgtataacc tccatacttt agagccaaag ttttaatatc
   111421 agtcataaaa ttcttctaac ctccatttat ttttctcgga aatgtagcct gtaatcactt
   111481 cgccgtcttc ctgataatca cgttcttcca gaattgcaac actctctaaa tcatgaatct
   111541 tgtaggactt tgaaaaaggc actcgcaggg taaatgcttc aaaaatttcc ttaatcttat
   111601 ctagcaataa tgcttgcaag ttttcacgac tgtcctcaga cttggcagaa atgagggtat
   111661 atggcgtttg ggtaggcgtg aaatcctcca ccaaatccgc tttattataa agcgtcaagt
   111721 gaggaatatc ttccatgtcc aggtctttca tgatggagag aaccgttttt tcatgctcct
   111781 cgtggtaagg attgctagca tcgataacat gaaccagaag gtccacatgc ttgctttctt
   111841 ccaaggttga cttgaaactg gacaccaact ctgtcggcaa atcttggata aagccaacgg
   111901 tatctgtcaa agttacttgg agattgcctc ccagatgaat actcttggtt gtcgcatcca
   111961 gagtcgcaaa gagctcatct gcttcatact gggtcttact ggtcaagatg ttcatgatag
   112021 ttgatttccc agcattagta taaccaatca aaccaatctt aaaagtgcta gactccaaac
   112081 gtttttctct gacagtcgca cgatttttct caaccacctt aagctggcgc tcgatatccg
   112141 tgatttgatt gcgaacgcta cgacggttca gctccagttg gctttcacca ggaccacggg
   112201 aaccaattcc ccctgcctga cggctgagca taatcccctg accaaccaag cgaggcaaga
   112261 ggtatttgag ttgggctagg tggacttgga gcttcccttc atggcttcga gcccgcatgg
   112321 caaagatatc caaaatcaac tgcatacggt caatgacctt aacaccgaga acttcctcta
   112381 gattgacatt ctgccttggg gtcagacgat tgttgacgat gacagtagtg atttcttctg
   112441 catccaccat aagcgcaatc tcttccaact taccagagcc gacgaaggtc ttggaatcat
   112501 atttttcacg tttttgtctg tagctatcta caacgactgc ccctgccgtt ttcgctaaac
   112561 tagccaattc ttccatggag aggtcaaaac tgtccatacc ctgcaattcc acaccaatca
   112621 gcaggactcg ctcctctttt ttctccgttt caatcatcta aaaactcctc tatctggctt
   112681 aaaatgcggt cttgtacacc agattctcca atctgataaa aggtgacctg catgcgatta
   112741 cggaaccagg tcagctgacg cttggcaaaa cgacgggtcg cctgtttaag actctcacaa
   112801 gcttcctcaa aggtctgctc tccacggaaa taaggaaaga gttccttata gccaattcct
   112861 ttagcagcct gtacattagg ggaatggtca aacagccact tggcctcatc caaaagccca
   112921 gcctcaaaca tcaaatccac tcggtggttg atacgctcat aaagttgact acgttcatca
   112981 tccaagcaga taatcagcgg ttcatacaag atctcttgat tttccaaatc ctgaccaaaa
   113041 tgggcaattt ctaaggcacg catagcacga cgacgattaa actggggaat ctcaaggcct
   113101 gcttgctcca ccaaatgggc taattcctca tctgaatatg gctccaaact agctcgataa
   113161 gctaaaatct cctcatgagg agtctcccca cctaggtggt aaccttctag caagctctgg
   113221 atataaagtc cagtcccacc ggcgataatg gctagcttgc cacggctctg aatatcctca
   113281 atagtcatct tagcttctga aacaaaatca aaagccgagt aagactcggt tatctctcta
   113341 acatcgatta aatgatgagg aacagctgcc tgctcttctg gactagcctt ggccgtccca
   113401 atatcaagtc ctcgatagac ttgctggcta tctccactaa ccacttcgcc attaaagcgc
   113461 tttgcaactt caatagctag agccgtcttt ccaacagcag tcggtccaac aatcacaatt
   113521 atttttgttt tcatcttttt tccttgaaaa attcccattt tttcgttact attattataa
   113581 cacaaaaagg tcagtcagaa aaatgtgacc tcttgaggag gctggctgat tgagaatata
   113641 aaggaggaag actcatggct aaaggattcg ctaaaggtct tgtaacaggt gtcgcaggaa
   113701 ctgtcgctgc cgttgcaggt gcagtatacg catttaaaaa gaaagtaatc gaaccagaag
   113761 agcaaaaagc agctttcatc gaagaaaatc gtaaaaaagc agctcgtcgc cgcgtatcac
   113821 gttaagaaac aaaagaagtt gggattattc tcaacttctt ttttctattc ttttaaatag
   113881 ctaggtcaaa cttcaactgt ggcttaacag ggtcataatc caccaactca aaatcttctg
   113941 ctttgatatc aaagaaatta gtcccatcag gaacatttaa aaccaagcgt ggttggcagt
   114001 ttgacggctc ccgacggagc aattcctgag cttgttcaaa ttgattatca tagatatgga
   114061 ggttgttgat gaaatagaag aacttcccaa ccttccaacc aaaatgtttg gcaatcatca
   114121 tctgtaaagc cacatactgc atagcgttga tgtggtgggc caccagcata tcattggagc
   114181 gctgggtcaa ggtcgcatcc agatagattt ccccatcaac acgccggaca tcaaacatgg
   114241 tctgaaaggc gcacgggagc agcccatctg tttcttcgaa agcttggtaa tcccagagcg
   114301 aaataatatt gcggcggttc caaggattgg tttccaactg tttgagaagc ttattgataa
   114361 tgtcgtgttt cttaacaacg gcaccatagc gctcaccaat ggttcccgtg tctccaactt
   114421 cccagtcatt ccagtagtga acattgtact tgtcattaag cacttctaag ctatttgact
   114481 ggtcttggta aatccagaga acttctttga tggcggattt gattgcaatg ggacgcaagg
   114541 ttgtgatagg aaattctcct ttagataagt cgtactcgga aaaggcacca gttacatact
   114601 tggaattagc aacagtccca tccttgtact taggacgagc ctgctctgag aaaacacctt
   114661 cctttagaat gcattcaata ttctctttaa aaatcgtatc tgcttttgtc atttcgtttc
   114721 acctcattca ttgtcctaac tagtatagca taaaaaataa aagaggaaca ttactaactc
   114781 taggttagca ttttcctctc tcattatctt attgcaatac aagtgatgct gctccgataa
   114841 ctccagcgtc atttcctaga gttgcaagag ctaatttagt agatgtgcgt acttgtggga
   114901 aactattttc atcgtaaact ttttgaacac cttgtagaag gaattctccc gcagctgaca
   114961 caccaccacc gatgacgatt gttgatgggt ttaggattga accaatgtta gcacaagcga
   115021 ttcccaagta acgtgagaag ttacggtaaa caatcaaagc aaggtcgtct ccttcttttg
   115081 cgagatcaaa gacagtctta gcaattactt cttctccgtt atcaatcaag cgtttcaagg
   115141 ctgcatcgcc ttcgtattca tcggcatagc gacgagtcaa gttgacaatc cctgttgctg
   115201 aagcaactgt ctcaaggcag ccttttttac cacaagtaca tgagattggc tggtcaaagt
   115261 caacagtgat gtgaccaagc tcacctgctg caccagcaac accgtgaagc aatttgcctt
   115321 ctgcgacgat accgccacca acaccagtac cgagtgtcat aaagacaacg tctggttggt
   115381 tatctccagc acccatccag cgctcaccaa gagctgctac gttggcatca ttatcgatga
   115441 aaaatggaat gcccaaagct ttttcaatct tttgtttgat tggttgaagg gttttccagt
   115501 tcaagttgta ggcaccgata acagtccctt tttcacggtc aacaacacct ggtgatccca
   115561 ttccaatgcc ttggaagtcc gctgctgcca atccaagcaa gtccaaacga tgttgaatag
   115621 actcaatcat atcatcaacg atatgacttc cctcatccaa aatgttggtc ttgattgacc
   115681 attttccttg gatttctcct gctgttgtta agattgcaaa tttgatagaa gttccaccaa
   115741 ggtcaatccc aataatcttt tgactcatca tattctcctt tttcattgtg tagtaattga
   115801 aaatgcttac agtactagta tatcaaaatc cattcactta tgcaaaggtt tgcgtaaatg
   115861 aattataagg aattttttcg cctaccagta tctgttaatc atctaaatga tcaatggcat
   115921 attgagctgc atcatttgaa aatttatcaa aatcagaagt taattgtcta tacatacgtt
   115981 tttttgacat gtggaataac gaattataac tttttgcctt tcctaaagca gcagaatatt
   116041 cactattgct atcattacta gaagaaactg tacttgcttg accttccttc caaactccgt
   116101 cagcgccaac ataataacgt ccaccatcaa cccattcatt gacagccatt ttaccatccg
   116161 attttagata gtaatttcct tgccatgtac tgtaagcata agaaccatct gatgtcaaat
   116221 aataccaagc ttgataagaa gagtcataaa tccattcact ctgtgccatt ttaccatcag
   116281 ctttcaggta atagcttccc tgccatgcat ttttcactag atttccattt ccatcaaagt
   116341 agtaccaagc gccgtcctgc ttaacccaac cacttgttgt tgctgaactt gtgttgattt
   116401 gaatagccgt tgactgtttt gctttaaaag cacccttagg agcatttttc aattcgcaag
   116461 ccacaccatc atgatcacgg tctaacttgg cagaataacc aggttctccc tcgtgaatat
   116521 ccgaatagcc attcgcccaa gcttccttac agctcgaaaa atggatgttt tcttccgcca
   116581 aaactggttg tgaaaacaag gctaaaattg gcaacgtcac cagactcatt tttaaaaata
   116641 gacgtttatt catttctttc tcccataatt atgatatcga tttcaatatt attttatcaa
   116701 acttatttca gcaattcaag gaaacttctg gtcttttcta caaactcctt tggttttgcc
   116761 ttattcaaga catgagggcc atcaggaatg atctgaaact gcgaatctgt taacagtcta
   116821 tggagagctt tcatagaact aagattcggt ttatctttgc tgccacaaat tagtaaggtt
   116881 ggataggagc aagtccctgc tatatccgtt aaatcaagtg tcttcaattc ctcagaaact
   116941 ccgaccataa gagtcttgtc tgctccctgt ttttcaaata ctcttttggg aagtagttta
   117001 aaaatcagca actgaagata aaataggata ttccctgcta atttaagcgg gcatcctgac
   117061 agaatcaaag ctcgaagatt tggtaaatcg taactggaaa gttctagtgt cagggcagca
   117121 cctaaggaca atccaatcaa aacaaaaggt tctgtctctt gagctaggtg ctgataaact
   117181 cgctctttag cttgttgata gttactaact ccagaaggaa ataactcgat agcctcagaa
   117241 ggataatctg tcagtagatt ccgaacttct ttccaagact ctgctgactg ccctaaccca
   117301 tgcaaaaata tcaatttcat ctagttctcc tcaaggctta gttcatacaa gcctctcact
   117361 gcattacagc cgtaaatagc ttctgcttgg gttaaatctg ccaaggtcaa gactttctct
   117421 tctacctgtc ctgtttctag caaatgctga cggtaaattc ctggcaagat tccaagtcgg
   117481 ataggcggtg tgtagagttt tccagcgatt ttcagaacca aatttcctat agaggtttca
   117541 agcagttctc ctgacttatt gtggtaaatc ttctcttgtt ctcctaggct caaatgcgat
   117601 cggtgagtgg ttttaaagta ggtaaaggat tgattcaaag cagcttcctg aagacagact
   117661 tgggcctgac aaaagcttgt actgagaggg gttaatactt gacgattgac ttctatctct
   117721 ccagatttgc taaggctgat tcgcaagcgg taatctcgat tagcttcaca atcctgacac
   117781 tcttcctcaa tcttgtgtcc caagtcttct gcatcaaaag gaaaagcaaa ataacgacta
   117841 gcttttctca gtctttccag atgttgatct tcaaacagca ggttcttctg gctgatttcc
   117901 cctgtcgtaa tcagttggaa gcgagcttgt ttacgataaa gaactgctgc cttttgatga
   117961 acctctcggt attcagattc ccatgtgcta tcccaagtaa tccctccgcc aactccataa
   118021 atggcttgac ctttgtgaag ttgaatggta cgaatggcca cattaaaaat ccgtcgtcca
   118081 tttggaagca agagaccaat cgttccacag tagactccac gcggttgagg ctccaagtcc
   118141 ttgataatct ccattgtcgc aattttcggt gcacccgtta tggaaccaca aggaaagagt
   118201 gagcggaaga tttcaacaag gtccacatcc tctcgcaact gactcttgat ggtcgaagtc
   118261 atctgccaaa cagttgaata ctgctctacc tgacacagac gctccacgtg ctcgctccca
   118321 acttcagaaa tacggttcat atcattgcgc aagaggtcca caatcatcat attttcagag
   118381 cgatttttgg gatcctgttc caaccaactg gcctgttcaa gatcttcttg gtcagttacc
   118441 ccacgctgag tcgtcccctt cattggtcgt gttgtcaact cgcgatcatt ttgctcaaaa
   118501 aagagctctg ggctcatgga aatcactgcc atctcgtcat gttccacata ggcattgtag
   118561 cccgcctcct gctctaccac catacgattg tagatggcaa aaggattggc acttaacttt
   118621 tgcttgagtt ggacggtgta gttgacctga taggtgtctc cctgcctcaa gtgatggtgt
   118681 atctgggcaa tggccttttc atagtcctct gcagacgtta cttcctgcca atttgagggc
   118741 aaatcaatat cctcataagt cagaggaata ggggaggtct ccaccctatc gtgaacagta
   118801 aagtaaagca agtactcgcc cagtagagga accttgtgaa ctgctaattt ctcctcaaaa
   118861 gcaggtgcag cctcgtagct gacatacccc accacatagt agccctgcgt ttgatagttt
   118921 tccacttgtg ccagcaaatc tgccacttct tctacatttc tcgttttcaa ctctttaata
   118981 ggctgggtaa aggtatatct ctcccccaaa gtcctaaaat caatcactgt ttttctatgc
   119041 atactttaag tatagcataa aataagaaaa ccctcatccg caaagcagat gagagatttc
   119101 gattatctaa agattgaagt tttaaagcta tctgtttgtt gaagaagttt tttgtatatt
   119161 ttctctttaa gtgcaacagt attgtcagat ttaactgatc catttttaag agtagcttta
   119221 tctttttcaa ctgctgcagc aaatgcgttc ttcaagtcat cgtaactact atatgtagta
   119281 ctgtcgattg taacagggtt aaatcctgct ttagctttat ctacaacttc tttgaagtat
   119341 gctttcttcc aatcttccaa tgtactgaat ttattatcag aaactttctt aatgatgaaa
   119401 tcatcaccta gagtattgtg accagcctgt ctagactcat ttttcagcat gttagaagca
   119461 tagtttaaga atcctttttc atatccgtag tacccccaca ttctgaatgt gttatgtttg
   119521 aatgacatag aaccaggagc accttcactt gtgttacctc cataaatacc tgcagtaata
   119581 ggtacagtca cgtaggccgt tccgaaccca gttggatcat atacattgtt tccaggtccg
   119641 tgtttcgtca taaaattatt atcaactaaa tcatctactg aatttagagt gatatttttc
   119701 tcatctgccg ttaaatcacg aactttatca tactggttct tcgtactagc tccacgaagt
   119761 tgcttatcca cttttttgaa ccaagcgttg tttaaatctt gatttgcttt attgaggaca
   119821 gcttctcctt caaggtaatc aagaagcatt aatgtgtcgt tgaaaccttt catgtagtta
   119881 tcaatttctg cacgagttgt aaggtcgttt ggatttgtgt tataccattg atttccatca
   119941 ttttgacgtt catacgccat atttagacct aatgcgccat attctccgtt tggatttgat
   120001 accgatggcg tttgtaacat cccctgagca aatgcttcaa gatccgtacc ttcacgatgc
   120061 caatgaccac catagtaagc catacgatca ttaacgtgag tagtttcatg tgtaaatgca
   120121 gatgttccaa agtcactaat taaatctgtc ataacgaaat aaactgcatc catcggttga
   120181 ggtgctgcaa aaatatatgc atatgcgcca tatccatatt tgtaaccatg atacttattg
   120241 attcgcccaa agaactcacg aattggagca taatctggtt tcccatctat atgaccatgt
   120301 ctactagccc atccgttcgg gctattatga ttatcccata caggagttgg aactacattt
   120361 tgactcttaa gaagtttatc acggacatta tcagtagcaa gacgtgacca aaaatctaag
   120421 taattaacct gctctttagc acgtttattg atctcactct tgaacttttc acgtttttca
   120481 tctgtgtctt taccatattt ttcaaacgaa ctaaacgaga tagtgttgta tgttgaaatc
   120541 ataaatagat gtgcattttt caagttaaga agaggtaaaa tcatgcgccc atgttgccca
   120601 ttattaattc cttcgtatag acgatatttt ttgttggcaa atgcagagtt cgttgatggt
   120661 tgttcaacta cataagcatt cttttcaata gctttcttaa accaaacatt tatgtctgtt
   120721 tcatttgtga ataatttcat attgtaggtc aagaagtcat gtaaactacc tttacctgtt
   120781 gcccctgaaa ttataccacg ataagcatct tgcgttctat ctccttttag attattttct
   120841 gcagaaccaa tattaatcaa tctatcaata acacttgctg tcttaccata aaaatcaggt
   120901 ttaaacatca taatatcttt aattgataac tcatcgtatt taaaagcata atattgattt
   120961 aagtatgcca gtcccatcat gattttagct ttattatctt caactttctt cagtaaagca
   121021 cgttcagcta attcgttatc gttgagttga tgatcttcat tttcaagtat ctgttttacc
   121081 aatttgtcaa gatttgcttt aacttcagag aaactttctt caaggaataa atctctaatg
   121141 tatccatttt gacgacctac actatttgca ttcgcatctt tcttagtatc tctcttaacg
   121201 agaagttgac gcactccatc agactctaat tctacactag atagcttaga ctttacatca
   121261 gtcatcaact gagcgcgatc tttctcaacc atatttggtg tatagagtat atctaaatct
   121321 gtaatactgt actcacgcac ttgttgaacg tttgattctt gacgagtaac attcaattct
   121381 tcctttgctc catcagaata gtgaatcata attttatcaa tatctgacaa atcagttacg
   121441 aattgaccgc tctttatacc tgtaacagat aatacttctt ttgtcaacaa gtttgaacct
   121501 tctacaagtt tgttaccttg gttgacaatc cattctttgt tatagagcgg ttgaagtttt
   121561 tcaatattgc gataagcttg ttcgcgagtc gcctcgtaat cttgtgttgt tctatactca
   121621 ttatcacgtg ttgtgagagc gttaagttta tttacaattg gatcggtaat tgtaaattta
   121681 tctgctgtga tagctgtctc tgcaatttta acatcagctt ctgattgtgt tataggttta
   121741 atacgattat gctgattaga atatctatat gtagaagtac cttcgctaac acctataaca
   121801 acgtagtttc gattaacatg gttacctgtg taatatggat catcatcaat atctttagaa
   121861 ccatagaaaa tttcaccgtt cttaactttc atcatagaaa cagtatcttc aatagaacca
   121921 tgataagtaa aacttccaac agcgccacca acttcaattg gtttttcaac gtctattgta
   121981 cctttaacaa cagatttttt aatagccccc tcagatccaa tagtaaagtt attcccttgg
   122041 ttttgtgacc agtaggctat acccgcagct ttagctcgct tacctttaat atgagcatca
   122101 acatatgctc tttcaacgta tcctttccag ttttctccca caatacctgt taagaagttg
   122161 cctccagtac caacagatgt aacattaccg ataaatgcaa cattaattaa tttaccactg
   122221 ccgtcaattt tgtctataaa tccagatacc cagtctttac ccaggacatt accagtaact
   122281 ttgacatttt caatggttgc attatttttg attacatttg caataggagc aactttatca
   122341 gcccaaggca tattaatatt tacattagca agattaatat cgtggatttt accaccttca
   122401 atattagcga ataatggacg ttctatatta tggattgtaa atctaccgcc gtcattactt
   122461 agtaatttcc ctttaaatgg tttcgttaca taagatttcc cgttaggttt tacatttgct
   122521 gcattcaagt ctgcaccaag tttaaactca cccgttggat tagcttgcat atcttttaca
   122581 agttcattga agttgtagta tacattattt acttttggta attgtttttc aaaataatga
   122641 acatattctt cactcagtgt atcatcagct ctacgttgaa ctaagtctgg agctttggct
   122701 acaactttgt acaatgtttt tccatcaaca acaacttctt caactgaact taccgcaagt
   122761 cttgtcactt tgttgtcatg agttgtcaca cgtaaataca attgggaaac atctgtcggt
   122821 ttttcagata ataagctctt atcagtttcg ttaccctcag catcaacatt cattaagctt
   122881 gtttctttaa tgtttttgat ttcaactttt ttaaggtcta attgaatttg tttatcttct
   122941 aatttctcag tttcttcacc ttctccacga tcataaacca ttgtagtaga tagggtgtaa
   123001 ccttgataat atttcaattt atctaaagta gcatttaaat tattttcagc taccgttact
   123061 tctttaacaa gttgtccatc tttatctttt agcgctaatt taattgattt aatttctaca
   123121 ccagctggtt tagtcaatgt ataactagct gtagcactct tcttcaagac atctttttca
   123181 gtattagccc attgtaatgt tggtttttct aacccttttg tacctttttt gataatctca
   123241 tcttgaggtt gttcaattac tgtttcctta actattggag cttcatttgt tttttctcca
   123301 cgaattgttt tataagtttc agtaatttgt ttcttacctt ctacaccttt ttgaactact
   123361 tgtcttgttc cgcgttttaa agtgtcatct tcttgttctt ttgtttcaaa aggaatgact
   123421 tcttctcttg tttcaactgt tgttacttca acttttggtt cctctgttgg ttccgtttgt
   123481 ttttctacag caggcgtttc cacttttggt tgttcaacag gttgattaac agtctcctct
   123541 tttgattcta ctggttcttc aaccttgatt tctggggctt ctgctggctg ttcatcttct
   123601 tgtttcggtg tctcttccgc tcccctatct tctttagaat tgtcttcttg tgatgattct
   123661 tttggtgtac ttggttgctc agcttgtgta ggttgcacgg gttgttctgg gacttttgct
   123721 tgttctactg gtggttcaac ttttgattcc tcagctggtt tgtctgatag ttgactttct
   123781 ggcttaactg ctactttttc ctctggtttt gactcaactt ctccacctac ttcttcaact
   123841 ggagctggtt ctgctgaagc ttcttttccc tcttctactt taggaagggt gtcgtcagta
   123901 ggttttatct ccgattttgg ttcttccttt ggactttctt ctgttttagg tgcttcctct
   123961 gtctctacta cttggttttc tgtcctagct tgctcctgat ttgttgttga ttgaggagtc
   124021 tcaacttcga ctacagtcac ctctccaggt tttgctgagg tttcttctaa aacagtgtcc
   124081 aagccaagcg ttttgaggat gtcacctgat agataaccaa catagcgata gccctccatt
   124141 tcaacaacac cctctcgact agccagcgct agggtcgcaa ctgggtctac agcccctgca
   124201 ctaggaagaa ctaccaatcc catagctcca actagaaaga cgctagcaat tttctttctc
   124261 ttgtagatta aaagcaagct cccaacagtc agcaaaccaa aagctgtcaa aacagatgct
   124321 tctgtccctg tttgaggcaa ctgatctttt tgatacacca aaccatatac aacttcattc
   124381 ctgtcaggct ttcctgtctg aattaaatct ttagcttctt gtgaaataat ctctttattt
   124441 acatagtgat aggtggctgc gtccactaca gaaggagcca tcaaaaggct tccaagaaat
   124501 acagagccta caactccctt aatcttacga attgaaaaac ggtctttttt aaacactttt
   124561 atctccttta ttcattctca aaacttccta atagcatctt gcggatagtg cgcacgcgca
   124621 cctccgatta attttggacg actagtcagt gccgttacat gggcatgacc aatctctctc
   124681 aaaatagggc gaatcggaac ctgaacatgc ttgacatgca tgccaattgc agtgtctccg
   124741 atatccaatc cagcatgagc cttgataaat tcaacctcaa ctggatcctg cataaactta
   124801 aaggctgcca actgccccga acctcctgca tgaagagtag gatggacact gacaatttcc
   124861 agatcaaact gctctgccac ctgacgttca acaacgagag cccgattgac atgctcacaa
   124921 ccttgaactg ctaaatggat acctctacta cctagaatac ccaagatagt ctccactatc
   124981 agctcaccaa tctcttgact ggattctttc ccaatctgac cacctagcac ctcactagaa
   125041 gatagaccta aaacaaaaag ggccccctgc ttcaaattgg tcttttctaa aacatcttcc
   125101 actacctgac gtgtttctct ttgaatctgt gtctcgttca tctctgttac ctctgttgtc
   125161 actcttctat cataccgttt tttcttgttt ttagcaagat agacaaccta gaaagtttgc
   125221 ccaattacgc ataaaactcc cagaattgac tgggagttag ctagtttcta ttctatttat
   125281 atatatttca actttcgtcc ctttttgggg tctagaatca atcttcatct ggtaattggc
   125341 tccaaaatga agtttgagcc gttgatcgac attttgaaga ccaactcccc cacgtttgag
   125401 ttgactttga ctactatcac cagcatcttg gaagccaacg ccatcatcct caatacggat
   125461 gaccaatccc gaatcctgtt tctggacaga aagtttaata tggccctgac cttccttttc
   125521 cttaatgcca tggtaaagag cattttctac aaggggttgt aggaccagct tgggtaagac
   125581 taaattatca aaggcaacat tttcattaat ttcgtattcc agcttatctc catagcgttg
   125641 tttctggata aagagatact gacggacatg attgatttcg tcagagagac aaatcaagtc
   125701 cttgccttga ttgagcgcca agcggaaata ggttgccaag gacttggtca cctgcaccac
   125761 tcgctgacta tcatgaaatt cagccatcca gatgatggtg tccaaagtgt tatagaggaa
   125821 atgtggatta atctggctcg aaagggcttg aagttggtac tgacgggtcg tttcttcctg
   125881 gctacgaata gctaccatca actgatcaat ctgatccaac atggcattaa attggcgagt
   125941 tacttctctc agttcatagg caccaacttc cttggcacga agattttgag caccagaagc
   126001 aatttccaac atggtttctc tcaaatcctt caaaggagca atccagcgtt taagactgaa
   126061 ccacactaag cagagacaaa caagaagaga tgtgacactg gccccaagca aggtccacaa
   126121 gagctgactc cgaacctggt ctaacttttc caatgatgac acgccaagta ccgtccaatc
   126181 agttcctgca atcttctctt gactgacgta ggatttgtga ccaggagtat aaccctgacc
   126241 tgtctcgatg tagggtttca tagcctccat tttgctagac gaactataaa ctgtgtgttg
   126301 aggatggtag acaaattcat ggttttcatt gataatgaag gcaaagccct gctgccccaa
   126361 ctggagttga ttgagatagg cttccagagt ttcataagaa atatccaaac gaagcacacc
   126421 aagattggct ccctttgcat caacaagttc ttgagtgaca gaaatgaccc actgactatc
   126481 tgatttacga gctggagtca aaacaggcat agctccctga tgaatagcct tttggtacca
   126541 atcctcagcc atcatatcag aggaagtttt catctgcaca ctgtcatctg tagaaatgac
   126601 ctgaccagat ttggtcacca gcacaacagt tttcaagtcc ttatctgact tcaagatggt
   126661 caaaaacaaa tctcggattc cctcgacctt gtcttgactg ggattctcag cataggccag
   126721 aacatccgtc tgctgggtca aaccagtcga gatggtttct agttttttga tataagactg
   126781 aataaagtgg ctagtctggc tgatggtcgt ttggctgttg ccctcaatgg tggcctcaat
   126841 ggctgaagaa cttgattgat agtagaaagt tccaaccaga gctaggagaa tgagaaagac
   126901 cagaaagatg gaaataacca ttctaactaa aagagaagaa cgcttcatcg gtcttctccc
   126961 ttcttaaact gacgaggtgt cacacctgca atctgcttaa aacgttgggt aaaatagttc
   127021 atatcttcaa aaccaacctt ctctgcgatc tcataaatct tcagatctgt agttaaaagc
   127081 aagagcttgg cttgtttaac acgttctctc accagataat cctgaaaagg caaacccaac
   127141 tctttcttaa tcaaggaact cagataggtc ggactaaaac ctaagtcact ggctaaagac
   127201 tttaaactaa attggctatc agccagatga gactggattt tctgggccat gtttccttca
   127261 aacctattag tcaataaatc ttgtaactgc tcttctttct cttccttgtc tagtttttgt
   127321 ttgattttcc ccaacatttc ctcaatatcc tgacgagaaa agggtttgag caggtagtcg
   127381 tccacaccta gtttgacagc agacaaggca taatcaaaat catcgtaacc tgttaaaaag
   127441 accaaatgaa cctgaggata ggtttctcgt accagactgg ccaactggat gccatttaga
   127501 tgaggcatgt tgatatcggt taaaatgata tctggcacct gcttttggat caattcccaa
   127561 gcctgccttc cattttcagt ctgaccgatg atttccatat cgtaggctgc tacattgacc
   127621 agtttagtca aaccttgtct taccagatat tcatcttcta cgattaagat tgtgtaggtc
   127681 atgatctgct cctttaccac ttactagtat cagtatagca aaattctcct ctaactgctt
   127741 aggaaagacc tcttatactc aataaaaatc aaaaagtaaa ctaggaagat agccacaggt
   127801 ttctcaaagt accgctttga ggttgtaaat aaaactgacg aagtcagtaa ccctacatac
   127861 ggtaaggcga cgctgacgtg gtttgaagag attttcgaag agtattaatc aacataatct
   127921 agtaaataag cgtagccttt ttcttccatt tggtctttgg gaataaagcg gatagagagg
   127981 ctattgatac agtaacgtaa gccgcccttg tcctgtggac catccgtaaa gacatgccca
   128041 aggtgagaat ctcctactcg gctccgcact tccatacgcg tcatattgta ggacttatct
   128101 tccttgtagg tgacaacatc tggactgatg ggttgggtaa aactaggcca gccacaacca
   128161 gactcaaatt tgtcttttga tgaaaagaga ggttccccag ttgctatatc cacatagata
   128221 ccggattcaa atttatccca gtaacggttt gagaaagctc gttctgtttg attttcctgg
   128281 gtaactgcat actcctcagg tgacagggtc tttttcaatt cctcatcact tggttttgga
   128341 tatttgctgg catcaatgac aggataggcc gcctgattaa cattgatatg gcagtagcca
   128401 tttggatttt tcttgagata gtcttgatgg taatcctcag ccaccacaaa attcttcaag
   128461 ttttcctttt caactgctag aggttgatcg tatttcttag ccacctcatc aaagacttgg
   128521 ttaatcactt ccaaatcctt gtcatctgtg taataaacac cagtacggta ctgggtcccc
   128581 acatcatttc cttgtttatt tttgctggtt ggattgataa tgcggaaata gtgaagcagg
   128641 atttccttga gagaaatttg cttggcatca taggtgacat ggacggtttc tgcatgacct
   128701 gtttggttaa tcaattcgta cttggttgtt tctcctctac catttgcata gcctgaaacg
   128761 gcatccgtca ccccgggaac acgtgagaaa tattcctcca ctccccagaa acaacctcca
   128821 gctagataaa tttcgtgcaa gtctgcgtct ttactaattt ctgttttttt cactgctttt
   128881 cctccttggc taactgccgc cttttcaatt tgcgaggcat ctgtctgccc tgcatttcgt
   128941 atcaatagaa catagaaacc ggttatggct agaaaaaata ctcctagcaa caagaagatt
   129001 tttaacttat cattcataag acgcctccta ggctaattcc ttcaaagttt gcaaaattgc
   129061 atctttttcc atgaatcctg gatgtgtttt gaccagcttg ccttctttgt ctataaaggc
   129121 ttgggttggg taagaacgga caccataagt ttccaaaagt ttgcctgatg ggtcaactag
   129181 gactgggaga tttttataat ccaatccctt ataccaattc ttaaagtccg cttcagattg
   129241 ctctccctta tgtcctggtg acactactgt caagaccaca tagtcatcac cagcttcttt
   129301 agcaatctca tccgtatctg gaagactagc cagacagatg gaacaccaag aagcccagaa
   129361 tttgagatag actttcttgc ccttgtaatc agataaacgg taggtcttgc catctactcc
   129421 catcaattca aaatcagtca cctctttccc tttagctgcg cttgttttac tagctgtctg
   129481 ctccgtcttc atttcatctt tcgtttggtg ttcactagtc acggacttgc ctgaacaagc
   129541 cgtcaaacaa aggagcgaac ctgctccaag aacacatgtt tgccattttt tcatattgat
   129601 attcctttcc attttattca aataattgac ttaaaattga agcatttcca aacagaacca
   129661 agagtcccat cacaataatg agaaaaccac ccactttttt gaggattccg agatagggat
   129721 gaagttttcg gaaatgtttc aaaatataac tagaggtcag agctagaagc aagaatggta
   129781 gcgccaagcc cagcgtatac accaacatga gaccagctcc ctgccaagct cctgaaccac
   129841 ctgaagccgc caaggccaaa acagacccca gaaccggccc cacgcaaggc gtccaagcaa
   129901 aactaaaggt caagcccaat aaaaatgcct gactatagcc cttaccattt tgcccctgtc
   129961 cttgcagttg tagtctcttt tccttataaa gccccttaaa gtgtagaatc tccatttggt
   130021 gcaaaccaag aaggataata attgccccag taagatattg gaaccaagaa gcataaagca
   130081 aatcgcctaa aaaaccagct ccatagccca acaaaataaa tataaaggaa attcctgcta
   130141 taaaggccag agttcgtaat aaactagtaa ctgagattga aaatttgccg ctagaagcct
   130201 gagcaccatc cttatcatct agtaacactc ctgtatagac cggtaacaaa ggtaagatac
   130261 aaggagaaaa gaaggataga atccctgcca aaaagacact tagaaaaaag aaaatatgac
   130321 ccataaagtt cctcctatca ttttattgat agatttatta tactccttcc attttcgaaa
   130381 aaacagggac aatgataggg gaaaatagga atttaatcag atgatttaga aatcttggac
   130441 aaaaactata caaaaaactg tcaaagcaca aaagcgcata gtatcaaggt tctataaagt
   130501 cttgatacta tgcgctttta taatggataa atagttagtc ttttttaaag accggatctt
   130561 tcaaactctg catactggca ttgataaccg cgcctaggat aacaatttta gcaatcaaga
   130621 taaaccaaaa catcataaca acaagaagaa cggaacctaa aattcggaca tccaccaaat
   130681 gatggacata gtaattgaga taactagaga acagagttag taaacctaaa atcactaaga
   130741 gaacaaaggc actgcctggt agggtatagc taattttcct gttagataga ttgggaagaa
   130801 aataataaag catgaccaag atagcaaaga ggagggcgta aatcagagga cctgccaacc
   130861 cttgtaaagc ctgatagata atgccatctt ttgtccaata atgagcaagt aaagccaaaa
   130921 tcatctgacc aaataagatc aaaaacaagg caaacgcaaa gaggagctgc aagccaaaac
   130981 tgactaggag acttagcatc tgatgggaaa taagtccacg actcttttcg acgccataag
   131041 ccttgttaaa agctttttgc aagaaattca tagattttga aaaactccat aacgccgata
   131101 aaacagaaaa actcaataaa cctgttgaag gttgcgtcaa gacttctctg gctatttttt
   131161 ccataccttc atagaggctt gggggcagga cgtctttcat aaagcccaga aattctccca
   131221 caggaatctg aaaatagggg aggatattga ccaccaccaa aagcaggggg aaaatcgaaa
   131281 tcaaccaata gtaggctact gcgacactgg tcaactcact atctgatgct tgataataat
   131341 gcaaaaaagc ttttaataaa ggcttgtcta tcagctcttt ccaccacttt ttcatgtcac
   131401 actccttcac ttataatctt atactcaatg aaaatcaaag agcaaactag gaagctagcc
   131461 gcaggttgct caaagccctg ctttgaggtt gtagataaga ctgacgaagt cagtcacata
   131521 tataatccaa ggcgacgctg acgtggtttg aagagatttt cgaagagtat taactaattt
   131581 cttcttacca attccaccat atcatacggc agggtattgg cagcttcctt caaggaatag
   131641 ttctctaagt tatttacatt ttgtcgtaat ttcttggcat acttagttgt aattaatcgt
   131701 ttttcttcgt attcgaaaat caacttgcgc tccagataat agcctctcag catttcatcg
   131761 atattgttgg gtttgacacg attgataacc cgttcgacaa aggaaccact gctgataata
   131821 gctgtttctc gaagacgaga ctcctgcata aaactaatca aagagcgtct gtagactccc
   131881 ttcaggtttt ccaaactttc aataatcatc tctgtattgg caagatagag ctctgcaatt
   131941 tggtcataat caagagcacg aagacggctt tgctccttgt ccttccagct acggaaggtc
   132001 tttccaagag taaaaacttc atgaaggaga aaacgtaaaa tcctcaaaga aacaaggaaa
   132061 taataggtca gtcttgaggc aagtttacga ttgattcctt gttctatatt tttcagataa
   132121 cgttggtaaa ctcggtaagc acgattgcta atgttcccct cttcataggc ctgctccaaa
   132181 ccatcacttt caatactaag aatcaagagt ttcaaagcag cccaatcttc ttgatcatcc
   132241 tggttttctt ggcttaaaat gagattttca atacgtccat gataattgtc aatagccgca
   132301 tagaggggaa gtttatttct ggtgtcttcc aactcttttt ccaactctag cgttacttca
   132361 ttcaaaatgg cgatatgcat gagataatcc ttgctttctt cctcttcatc agaaagatga
   132421 ggcaagacca agagacctgt taaaaagctg acaagcgtca cacctgcaac aaggaaaagc
   132481 aagagaggat actcctgttc taaattactt ggtatcaaga gaatcgtagc aatcgacacc
   132541 gttcccttaa cacctgaaaa ggtcaagaga aacatgtcct tcatatattt atttagcttt
   132601 ttcttgaggc gtcgggttct ataggcataa tagccataga tcataataaa acgaatgaca
   132661 aagaggacaa aggtaagggc gatgagagat agcaataaaa gtagaggatt atagattgga
   132721 ttggtcaaga taggttctgc tatcatttcc aactccatcc ctaaaatcac aaagacagaa
   132781 ccgttgagca taaaggtcac tgtatgccag accgtctcgg tcaccgtatc cacttgggct
   132841 tcgaggagcg tgattttctt gaagcgactt gcctttaaaa ttccagcaac tacgacggca
   132901 ataatccctg aaacatggac ttcttctgcc agaaagaagg tcactagagg caaactcaat
   132961 tctaataaaa gttcactggc aatatccgtt gcgcgcacac ttagcaagaa ggtatggagg
   133021 aagcggttgg tcatggctgt taaaaatcca attaaaaaac cgcctaggat tgaaaagatg
   133081 agcgaactgc tagcttgccc cagagaaaaa gctccagttg tccaagctgt caaagctacc
   133141 tgaaaagcca ccaaaccaga agcatcattc aagagtcctt cgcccttaag aatattggac
   133201 acgcgcttag gaaagctaaa acgctccgaa agagaggcaa aggccaccaa gtccgtagga
   133261 ccaagggctg caccaacagc caagcaagct gccaagggaa ggctgaacca aagaagatgg
   133321 gccaagccac ccaaactcag ggtcgagata aaaatcactg gaaatatgag ataaacaatg
   133381 attcgccagt gttttaaaat agccgtaaca tctgcttctt cagcctctcg gaaaagcaag
   133441 ggtccgataa ccagtgccaa aaacaactcc gtattaaggt gaaagtcagt attgggtaaa
   133501 aagagaccaa tcacaattcc caaaagaatc tgcaccaaag ggagaggcaa aaagggcagg
   133561 agcttattgg ttgtacttga gacaatcaaa accagtaaaa ataggatgag gtaaatcagt
   133621 aattccacgc acgtcctcct taatcttttt tacaacagga ttcaaatatc tccttctgct
   133681 ctttgatttt ttggtcaatc ttggaacagt ctttgtgctc aatttttctc tggcaccgtt
   133741 ccatttcaag agcaactaat tttttcttga ttttaagcat ttttttgctc atatgtgctt
   133801 ggtctagcac gcccaccgat cgttcgtggt gggttgattc aacaaaattc tggcgcatgg
   133861 catccagctt ttcgtgtagg tattgtttat ccatgtctgt atctctctaa tttttcaatc
   133921 atcactaaaa acggcgggtt gttgacttgg tttaaagttc ggtaaatggc agctgtgtac
   133981 tcttgttggt tcaactggat cacaaaatcc aagacagcat ctctctcgag gtcgcctcct
   134041 tcatgaccat agtaaatcat aatagcaatt cgtccacctt tgacaagtaa gccacatagc
   134101 ttttctaatg cctcaatcgt tgtctgcggt cgggtgatga cagacttatc agctgacggc
   134161 aaatagccca gattaaaaat ccctgcctta gcttttgtca caaactggtc cagtgtctca
   134221 tggccttgca agattaactg ggcatttgtc aagccagcct gatgcaaacg ctcttgggtc
   134281 ttttccaagg cttgcttctg aatatcaaag gcatagactt gcttggctag cttggctaaa
   134341 aaaagcgtgt catgaccatt tcccatagtc gcatccacta cgacatcctc ttttgtcacg
   134401 acctcagcca aaaaatcatg tgccatctca agtggtcttt tcattttcaa actcctgttt
   134461 tacagccttg catccttgaa cacttccacg acgtcgcatc tccatctcaa tgctgttgag
   134521 gacttcccat tttttgaggc tccacatagg accaatcagc atatccctag gcgcatctcc
   134581 tgtaattcga tggatgacga tatgtttggg aataatttcc atttggtcac agatgaccct
   134641 gacatattcg tcctgactca tcaattgtaa acgtccctca tggtaatctc gttgcatacg
   134701 agtatttgtc ataagatgga gcaaatgcag tttaatccct tgaatatcgt tatccgtgac
   134761 acaacggcgg acattttcaa ccatcatctc atgggtttca ccaggcaaac cattgatcaa
   134821 atggggaaac aatctcaatc ttgggatact ttctcaaacg cttgaccgtt tccacctaca
   134881 attcataaga atgcacacgg ttaatcaggt cagaggttgc ttcataagtg gtctgcaagc
   134941 ctaattcaac cgtcacatgc atgcactccg ataactcagc caaatattcg atggtttcgt
   135001 ctggtaaaca gtctgggcgc gttccaatat tgattcctac cacacctggc tcattgatag
   135061 cctgttcata acgctctcga ataacttcca ccttttcatg ggtgttggta aaattttgaa
   135121 aataaaccag atacttctga acatccggcc acttacggtg cataaagtca atttccttat
   135181 aaaattgctc acggataggc gcatctgggg ctacaatagt atctccagaa cctgaaaccg
   135241 tacaaaaagt acagcctcca tgagccacag ttccatcacg attgggacag tcaaatcccg
   135301 catcaatagg gactttaaaa gtcttttctc caaagagttt tcgataataa tcattcaagg
   135361 tattataaga ttttataact ttcattataa caaaaatcac ccacaatctc aaaagcctga
   135421 ctttcctata aattcctctg tttctcgttt ccattagcct ttttttatga tacaatatgg
   135481 gtatgatttt aatgaaatta gcatctattt tattattgat actgacctta gtcgtctgca
   135541 ttatcctaac caaacttttt agattaaaaa aactaggacg aaactttgcg gatttggctt
   135601 ttccggtctt ggtatttgaa tattacctga ttacagctaa aacctttacc cataatttcc
   135661 tccctagact ggggctagcc ctctcgatcc tagccattat tctcgtcttt ttcttccttt
   135721 tgaaaaaacg cagcttttac tatcctaaat tcatcaaatt cttctggcgt acaggatttt
   135781 tattaaccct tatcatgtat atagagatgg ttgttgaatt gttcttaatg aaatagtcga
   135841 atccctaagc attttctagg gatttttgct ttctctacaa aatagtatag acaataacac
   135901 tatacaattt tatacaaaga aaagagtctg ggacaatagt cttggtaaaa tagaattgca
   135961 caataaacca tttagaaagg ctatcccatg catattcact ataacacaaa tcaaacaact
   136021 ttaccactag aaatcagttc cttcttacca caagaccatc tcgtctttac tattgaaaaa
   136081 gtggtgaata ccttggagga acatcacttc tacgccttct atcatgcctt tgatcgcccg
   136141 tcttatcacc ctaaaatgct tgtatctact cttctatttg tctattcaca agggattttc
   136201 tctggtcgaa aaattgaaaa atggaagagt tagtgacctt agattgtttg tttattgacg
   136261 gaactaagat tgaagccaat gccaacaagt atagttttgt gtggaagaaa acgacagaga
   136321 aattctccgc caaacttcaa gaacagatac aagtctattt tcaagaagaa atcactcccc
   136381 ttctgattaa atatgccatg tttgataagg aacaaaagag agggtataaa cagtcagcta
   136441 aaaacttagc gaattggcac tataatgaca aggaggatag ctacacacat cctgatggct
   136501 ggtattatcg ttttcaccat accaaacatc agaaaacaca gacagacttt caacaggaaa
   136561 tcaaggttta ctatgccgac gaacctgaat cagcccctca aaagggggct atatatgaac
   136621 gaacgctatc aaaacttgaa agctaaagaa tgtcaggcac ttttatctcc ccaaggtaga
   136681 cagattttcg ctcaacgcaa gattgatgtg gaacctgtct ttgggcagtt aaaggcttgt
   136741 ttgggttaca agagatgtaa tctgagaggc aagcgtcaag tgagaattga catgggattg
   136801 gtacttatgg ccaataacct cctaaaacat agtgaaatga aataagaaca ggacaaatcg
   136861 ataaggacag tcaaatcgat ttctaacaat gttttagaag tagaagtgta ctactctagt
   136921 ttcaatctac tatacaataa gagaacgact caaaattaaa aagctagagt tccgcaattg
   136981 gaaatatcta gctttttttg tggttgagaa ctattttgtc ccagactctt tatcttctat
   137041 ttaggacaag agtttttctt tggtctttaa tgataaagaa ggtatcaaaa tttctagtct
   137101 tcttttttac ctttagtaac tactaatcct gcactcaaac ctagaagagc taaacctgct
   137161 actgctgctt ggcttgccgc actacctgta tttggtaact gggctttatt agtttgacta
   137221 gcttcacttg aatcaattgg ttttgtatct gctttttctg acacttgtgg ttttttagct
   137281 tcttgagcta ctggtttggt tccaaccaag acgatgcggt ctgtcggagc ttctaccact
   137341 tcacggagtt tttcttcctt acttccatca ggattaatcg ctgtaaagat acgttcttta
   137401 ccagtttttc cttcttgttc tacacgagtt tcacctagat acagtgttga atcttttttc
   137461 tcaactgtct tgtatgccaa atctttttca acaaattcga gttttggaag atcttcttgt
   137521 acagcagcaa ctgtcttctc agaaactggt ttttccttag tcaagtggat acggtattcc
   137581 ttgacttgtt ttccactttc tgaaacgagg cgaacaagta ctggaaggct atcttctcca
   137641 ctatctacca cagttgaagc tacttgattg ttttcttcaa ctgagacttt tggccgttga
   137701 cctttatagg taatttgata gtcttgacga ttttcagcga aatcagcaag ttcttttcca
   137761 tctacaagaa tcttcgattg cgtactttct tgaggcaatt cactcggtgc caggaaggtc
   137821 atctcaatca tcgcaacacc gctcttgtca gctttacgct ccatacgcca tctcatggct
   137881 ttggctttga cagctttaaa ggtaacgtta atttcatcac cggcttcaat gtctttatcc
   137941 gcacgataat gcacagcttc ccaattttct ggattgttga atggatggtc tgcgtcgtag
   138001 gcttggtagt ttgaatagta ggttggcatt tcaaactctg gaccgacata gcgttctaaa
   138061 acgagtttag atggtgcatc cgtaccacta tctgcaaaga actgaacttt tccttgtgca
   138121 acagtccgtt ctacaatctt accattttca cggaagatca cacccgctga tacttctgga
   138181 ttagaagatg gtgttggtga ccagtttgtc caacgacgat tttctgaatg atctccgtca
   138241 ttgagatagt caacgcggtc atgagagttt ttgtcaatat cattggttgc tgaagcaaag
   138301 gcctggttac tgttttcatc atagttaggg ttatctgaaa gagtctcacc aagtttgtct
   138361 gtcactcgta cagtgacctc agcaacaagg ttactaccaa ggacacggcc tcgaacagta
   138421 aattgacctg cttttgtcag attttccgct ggaacttctt cccattcaac tgtcaggtct
   138481 tttgtttcgt agccgtcttt acctgtgaag taaactggaa ccttagtcgg caattcaagt
   138541 gcttgaccta cttgtagcaa gcgaacttgt ttaaccgcag caactggttt atgagaaagt
   138601 aagttcttat ccttagtgaa gtgcagacgg tattctccta agatgtcgcc attttcagct
   138661 ttcgcgatga cacgaactgg ctcaccttca cgaacgcttg gaacgacggt agcgagacca
   138721 ttgttgctaa cacttgctgt gactgccgga acttttccat ctacagactc aaggtagtag
   138781 tctgtcaaat cagggttgaa gtttgctaag tctttgccgt caacttggat tcttgtttgt
   138841 ccttgtttgg ctgccgcaac ttgtttcgca aagatttgta cctctgtgat agacgttcca
   138901 cgcttgttat ctgctttaac catgcgaata cgaatagcat aggtttcaac tttatcaaag
   138961 ctaaagtggt tcatttctcc agccttgagt tgagcagggg cttttagatt agtaactggt
   139021 ttccagttgg cagaatcatt aaagacatgg tcctcattac caacaaaact agggttttta
   139081 ggagctgttg ggacagtctt accaacataa tactcaatca cataagactt cggtgcacca
   139141 actccatggt cttcgtggaa tccgacactt agattatcaa cggagcgttt gctcaagata
   139201 cctgaatctc caaacagaac accgactgaa gcttctggat tactacgatt ccagtttgtc
   139261 caacgattgg ctggttggtt attgtaggaa atgagcttgt cattaacatt tgaaactggg
   139321 tcgcttggat ttgaatctga agcaaaggca agtggcaatt ctgaaccggt ccattggtca
   139381 gaaatgtttg caccttgctc agtttgagca gatacgcgaa catgaagttt agttgttaat
   139441 tgcgtacctt ctaagcgacc attaactgta aagacacctt ccttagcgta ttgctctgga
   139501 cgaatcgcat cccatgcaac cttagctgat gaaacgtgac catttgaatc atatgtccga
   139561 acgctttctg gtaattgtgg tgcttctgcg attggagttg tcacactgac ttcttcaact
   139621 gaaacgatac cttctacaga gacttttgca cgcgcttcaa ggtcaattcc ttcaacttta
   139681 cctagtactt caaatgtttg ataggagtct agtttttctt tcggaatagc ttgccaagtg
   139741 actttgagag ctttagggaa acctttgtca tactcaaccg ttactgttgt tggaagagta
   139801 ggtttttgat gcaaatctgt cactacattt actggacgga tagattgcgc aatcttcttc
   139861 tcagtattgg cctggatagt gagatcaact tggcctttag ctccctcata ttccgctttg
   139921 agagtgactg ctcctggctt atgtaactca agcattcctt tacgaattgc gacttcccct
   139981 tcaccacttg tagagaaggt tactttatca gctggtaata cagcttgcgt tccatcttga
   140041 tagtgagctc gaaccgacaa tttgacagtt tggtcttctt tgagactgtc agctttttcc
   140101 acttgcaagc tcaagtgagc aatttttggc gcttcttcaa ggaattgaat tgcataggtt
   140161 tgaagaggac caccatcttt aggctgaata aagatgctcg cacgcatgcc gtttgctgcg
   140221 cttgcttgaa gaactgtcac atcagcattt tcagcacttg ctgtgacttc tggcagttgg
   140281 gcaccataag atagagtacg atattgcatt ggttgtcgac tagtaagacc tgttactgcc
   140341 tcacctccaa cagtaacagt tggcactaca ggtgctgcag catttccttc ttctaccaca
   140401 agggttgcat gaatagtttc tccagctaac tgaccagtca tttgaatacg tgatccagct
   140461 actgaaagtt tggctttatc tacttccgta atctcccagc tatctacttc gtactcttgt
   140521 acacttccat cagtcaaaac ataagaaaca gatttgtcta cagaattcaa gtcagtattt
   140581 ggagcaatac gtttaactgt tggtaattct ttcgcaattg ctagaacctc gacatgagcc
   140641 tctacctcac gtccatttgc tgtaccttta acagtcacaa ctcctgcttg actaacatcg
   140701 acttgagacc aagttactgg aagtttttca cgactaccat cgctgtatac aaaacctact
   140761 gttttcggca tttttggttc tttaccaatt aatgtacgaa ctcttgctac ttctgtcccc
   140821 aaaacagcct tctcttgtcc ttctttttta ccagtaaaga cagtgacttg gttcgatttc
   140881 aagagatcag agtgggcagt cagggtgaat ttccctgctt gttcagttga tttgacaatg
   140941 gcaacacctt taccattaaa tgctttacga atccaagaac catctgcttg cgccttatag
   141001 cgttcacggc tggcttgttc tccgttatct acaccgacca gttgaccttg gccatgcaat
   141061 tggaagcgaa ccagattatt agcagttgga accacattcc cctggctgtc aacaatttca
   141121 tagtagatgt aagtcaagtc ttttccatct gctgcaatcg catggtcttc cttaataaga
   141181 cgaactgccg ctggcttacc agcagtcgta atcttatctc gagcaatttc cttgccagat
   141241 tcatcacgag caattgcttc caaggtaccc ggttgatagg caactttcca ttcaagataa
   141301 agttcattag catttgcacc ttcttggtaa gtctgcccat cgctggtttg ttttttattg
   141361 aaagtcttaa gaccaagaga ttttccattc aagaacaatt ctacactaga agcattcgaa
   141421 taagcacgaa ctggaatctt accttctgag tcagctactt tggatgctaa ttctttgttt
   141481 tcccagttcc agtgaggaag aaggtgtacc atcggtttct tcttaacaga aacccattga
   141541 ctttggtaga gatagaagtc atgttttgga atgccggctg tatctacgat accaaagtaa
   141601 gagctcttaa caggagtttg attttggttg tgccatggtg taggttcacc aatatagtcc
   141661 gtacctgtcc agataaactg tccagcatag ccagcgttgt cacggtcaaa agtccatgaa
   141721 gcggttgctg ttttccccca accaacacga tcatttccat aatctgactg ttcataatta
   141781 cgctcaggtc cattgctatg tttcaattca cgttcagggc gatagtaact tccacgtgta
   141841 cgggtagctg aagatgtttc tgatccataa atcaaccatt tgggatgctt agctctaagg
   141901 gttttgtaat tatcttcaga atagttaaat ccaacagcat cgagttcatc agcaattttc
   141961 tcatgccctc cgctaccatt accgaaacgg aatttatctg ctcccatggt aacatagcga
   142021 gtcttatcaa catccttgat aaccttgacc aaacgtttaa cagttgctaa agagtgggca
   142081 tcaccattag cttcacctat ttcattacca attgaccaca tgaagatagc agggttgttt
   142141 ttgcctcttt cgaccatggt acgtaggtca aaatcagacc atttttcacc ttttcgagct
   142201 tctgggtgag tggcatcttt ttcaaagaaa cgtccatagt cataaggttt cttgccacca
   142261 taccaagtat caaaggcctc ttcctgaacg agtaaaccta gttctgctgc gatttgcaag
   142321 gtttgctcac tagcagggtt gtgggttgta cggatggagt taactcccat ctccttcatt
   142381 tgtttgagac ggcgatattc tgctttatag ttttcttctg ctccaagcgc cccatggtcg
   142441 tggtgcaagg atactccatg gaatttaata cgttcaccat tcaaagagaa accttcattt
   142501 ggagtccagt gatagtaacg gtaaccaaac aaatccttct tagcatcaac caattgaccg
   142561 tcacggtaaa cacgcgtaat caattcgtac aaggcaggtt tgtcatttaa aacggtccag
   142621 agttttggtc tttcaacttc taaaatcgca tctaggcttg ttgattcatg tgcttttaag
   142681 gtacgactcg ctgtacgaac taagcctgtt acagcatgac cacctcgttc aacgatttga
   142741 tattcggcta caagttcatg gtctttgtcg tccgtattga cgattttgct ggtcacatga
   142801 gtttcaacct tgccatgttg ttgttcttca agttttggtg ttaaaatagt tgtcccattt
   142861 ttctcaacat gcaccttatc tgtcacttgt aaagtcacat cacgatagat accacttcct
   142921 gaataccaac ggctacttgg ctgtttgttg actgcatgga cagcaatcac attctcacga
   142981 ccatctttgt gaaggtattt ggtgatatcg tatgagaact ggttataacc atttggataa
   143041 tgccccacta actgaccatt gacataaact tgagaatcca tgtagacgcc atcaaaatta
   143101 aggcgaacat ttttcttgag gtctttttca tctagtttga aagtcttgcg ataccaagct
   143161 tccccaccgt tgagctgtcc accttcattt tgtgcaggag attcatgatc gaaatcgtta
   143221 aagatactcc agtcatacgg taaatctaat tttttccacg tagatacgtc tgcatcaggt
   143281 ttaatggctt ccttagaatt tgcattgagt ttaaagtacc aattttgatt aaaatccact
   143341 ttcctgtctt caatcatttg attcacttct tcatttgtta cagctttagc atcttccttg
   143401 agcggttttt cttgacttga agcttgtgat tctatccttg gagctttttc ttccggttta
   143461 gcagacactt tttcctcttt ttgagttacg gcttcatctt ctttcttctc agatgcaata
   143521 gcctcagttg aactaggttc actttgttct gtcctttcaa ctacattttt agtttccaaa
   143581 gctttatcag ccttttcttc tactatcatt ttttcctctt taggtttctc agcagtatga
   143641 gtaataagtg tttcatccgc ataaactaca gattctccag ctatatttcc tcctaataga
   143701 actgcacaag tcccaatcat tactgagcaa gctcccacag caaacttacg aatgctataa
   143761 actcttttcc gattccaatg gcctttcccc ataaaaccct ccttatatta tatttagtgc
   143821 agttagctac taccaaagcc caagtggtat acatggtatg acaacctagt ttcaacaatt
   143881 tacactctgc gaaaatccaa ttcaaacttc gtcagtgtcg ccttgccgta gatatgatta
   143941 ctgacttcgt cagtttcatc tacaacctca aaaccatgtt ttgagctgac ttcgtcagtc
   144001 ttatctacaa cctcaaaact gtgttttgag caacctgcgg ctagcttcct agtttgctct
   144061 ttgattttca ttgagtttat attttatagg agcgcattat tttgcttttg ctgcgtactc
   144121 ttcgttacgt ttgatcattt gttttctgta ccaagcaaag ataccgatat agaatacaag
   144181 gaagactact gcaccaagga ttgctttgat atcaccagtt gtagtgttac caattgtcca
   144241 accaagaagt ttttcgattg gtccttcaag agtagagtga gtaatcaatt gagtttggct
   144301 cacaccttct gggaaggcac ctacaccttt agcaagttct gttgcaaatg gtgcaataag
   144361 tgtacctgaa agaaggaaga gtggcaacaa gagtgttccg aagataatca tacggagcaa
   144421 tttaccacga gttacaacca agagagctgg agtaacaccc atagcgatga tacctgcaag
   144481 tggcaagata ccatttccaa cttttgaaag aagcactgct tcaatcaaca tgattggtgc
   144541 aagtacgttg gcacaagccc agatttcagc acgaccagcg atgaatggcc agtcaagacc
   144601 gatattgaat ttacgtcctc gaagacgttt agtagcaacg tttgtaatac cttgtgatag
   144661 tggttctacg gctgcgatga accatgaacc gataagtgag aagagttcca aagatacacc
   144721 ggcagtcaaa ccaagagaca accatccttt gataacaaga cgccatttat ctgcatctgc
   144781 aacacctgca attggatgtg gagttcccat aataccgata acgataccaa ggatgaaacc
   144841 gatgaagaat ttagatcccc agaaaccgat tttcttgttc aatttagcag catcaaagtc
   144901 atatttatca aggcctggga agaatttttc aaaaatctta tccaaaacca tgataactgg
   144961 gttcatcatg tagttcatgt gagttgatgt cattggtgat gaacttgggg cgttaagaag
   145021 gtcatcaaat gtaggtttca tcaagtcaga gttgataatt ttcaacacac cgacaaggac
   145081 gatagctgct gtagcaataa agagtgaaac cccttgactc acaccattgt tatcagcata
   145141 ccatttaatc aagagacctg tgatagacaa gtgccagata tcaaagatat cgacatcaag
   145201 tgtatcggtt ttcttcatag caagcatcac tacgttgaca atcaacatga tgagcaagaa
   145261 gtatagtgtc caagcagaac cccaagtgat tgttgcgagt ggtgcccaac caacgtctgt
   145321 aatactcaat tggataccag tgttttcaac gaattttgca agtgatgctg agaaagcacc
   145381 atttagcata ccgatgatag caccgatacc tgtaagagcg atggcaagtt tgataccacc
   145441 ttcaagcgct ttggagaatt tcactccaaa aagtaaagcc aatactgtca aaatgatcaa
   145501 catgatgaca ggtccaccca tttctaagat gggattgaaa acctttccga ttaggtcaaa
   145561 gattgcatcc ataacagttc ctcccttttt tatgttatat gaatgttaac aaattagaat
   145621 tagcttaatc catgttcttt aatagctgct tcaatattgt caaatactgg agcgctcatt
   145681 gctgggatac ggaataagat tggcccagct tcgataactg ggatacctgg ttcaaaacca
   145741 aggtctgttg cagcgattgg tgtaaagata tcgtaacctt tcataaggtc ttcgtttaca
   145801 tctttcacca tgactgcatc acagtgaaca tcataaccac ggtttgaaag ttcttcttct
   145861 agagcacttt taatttggtg acttgagtta acacctgcac cgcaggcagc aagaatttta
   145921 atcatttgga tttcctccga ttttattttt taatagacaa gattaagcgg ttgcttcagc
   145981 aatgtaagca taaagttttt ctggttcaga aatttttgat aggtcttcaa gatgaccatt
   146041 tcctgtgaaa aagtccatca actgagccag aatgttcgtt tgacttgaac ttgaattgtt
   146101 aatgataaag aagagtagag atacttctac ttccttatca ggagctatca tattgtgaaa
   146161 agttactggt ttttctaatc gaacaaccac cactttctca gctagattat gaacaatatc
   146221 tgtgtgagga atcgctacat ttggcaagtc ctttcctaga aattccatat ctaaaccagt
   146281 tggaaatgac ttttcacgcg tgatcaaggc ttcacgataa gttggagtta caatttctcg
   146341 ttcttccaat aaagttgcaa cctgatcaaa gagatgttct tgattatccg cttctaagca
   146401 aaacacaagg tttttgtcaa agaaataatc taataccata agtttttccc ttctttccat
   146461 taactttatg ccataagtat aacactatat gaaaccgttg tcaattactt tttgttcttt
   146521 tttgtctctt tttttatatt tttgttttgt ttatagtttg ttatataaaa ataaacacac
   146581 aaacaaatac tccaagcatt ttttctgttc taatactcaa tgaaaatcaa agagtaaact
   146641 aggaagctag ccgcaggttg ctcaaaacac agttttgagg ttgtagataa gactgacgaa
   146701 gtcagtgatc atatcgtaac cgtccaatag acttcgttat tgggcggtta cgaaaaactt
   146761 ccttccaaat aaaaaggaat taagcaacca aacgctactt aattccttga aattgtctca
   146821 tcacctctat tagcctttaa attttgatag actctatttt ctaatcaata tgaccaatat
   146881 tgtcaatact aaccctttca atcaattcat tagttatcta aactaagtcc attaataact
   146941 ccaaatagta tcaatagtga agtaaactaa ataattgagt tataaatggc tgttttcaca
   147001 aaactatgtc atcacctcac tatctaatct cagtacataa accatttttt tctatagctt
   147061 ttgtcttaat cttgattttt tttcttcaat ccaagaaaaa ttcctactat aaacattatt
   147121 ccggcagcta atagtgtctg ggctccgctt gctgttccag tttttggcaa cttattagga
   147181 ttgttagtag ttgatttact actgatattg tttttatcaa gaactgtagc tgtaacatcc
   147241 ttagttgaat cagatttttg tgaatgatct tctctttgta aatcctcttt tctgtgactt
   147301 tcatttaatt gactatggtt tacttgtggg ttatctttct ttttcgatac atcaaaagta
   147361 ggtttatttt cttcctcctt tttctcctct attttcttga atacaggttt tataaaggta
   147421 tcttttgata gattaataac atagccagcg tcttttttac cttcgaaacc agaaatttcc
   147481 caaccatcaa attggtatcc tttttctaat tcacccttat aaacaggtaa aataaaatct
   147541 tcttccgaca ctatcgttga actcatttct tttccatttt gaatggtcac agttacccta
   147601 tgaggtttta attcacttac ctctcccgta tctttattta aaatgaattc ttttacggtt
   147661 gtatttcttg caaaatcttt tacaacaatc ttaatgttta gtgtcttgtc tgttatttgt
   147721 ttaatatcat caaatgatgt atattctttt ccatttacat aaatatgttg ttcttgaatc
   147781 tcaccatcga atccattatt tcttttatca ttgatgttaa agactacaga ttttccatca
   147841 gcatattcga tactagtatt tcccttagga tcaatgttta cttcgggttt aacattatca
   147901 tataaaaact gatagtggac tccaactgct ttagcattca aatcgctata gccagtttga
   147961 agataaacat ttccatccat atctgttacc ttatctggaa atccgtttgc tttatagtct
   148021 ttcattcccc agtccatgat gtcaccgtct ttaacattca gcttaatatt aaaatctcta
   148081 gtgttatcaa tgtgtaaatc tccgtagatt aaataattat ctacaaccga ttcattaact
   148141 ctcaattccc agttaaaacc acccttatca gaaatcttac ctcttaaata aaattctgga
   148201 tttcgtacat aaattttatt agatttagat ggattaaagt agttcttatc cattgaaagg
   148261 tttactggtt tggtatcaat aaataacatg gagccatctt cttttatagc ttctacattg
   148321 gacttatcct ctccagtgta ttctttatca tccttaccaa ataatacaag tttagaagaa
   148381 tctgtcacaa gatttccgtc tttatcgata gcttcccctt tatcgttcat tttaaatgta
   148441 aacacttgat accttataat gttaaagccg tccaaagccg acattaatac agcttgggta
   148501 cttcttccat cttcaacatt tctactatca gcataaattg ttgtttctga aaggactctt
   148561 agattaggat tggccttttg tatttttgct atatcttcct tgctatagac tccatttcct
   148621 tctaacatat ccgtttttcc aggattatag gtagtcactt ttagtgcata gccttttctt
   148681 agaatgatgt tatcctttaa cagatattgt tgtttttctg aatcagaata gattttacca
   148741 gattccattt tagttaaatt gtctggtttg ttttttgaaa ggtctccttc tcctaattcg
   148801 attacattcc cataacttga tacataggga tattctgctt tagtttcctt atttttttca
   148861 ggcattctaa ttttagtttc agcttttatt tgattgtcat ctttaacaaa taatctcata
   148921 tctccagcaa aagctaatcc atctacaata tcattaatat tagcgtataa atcaaatatc
   148981 atcgtttttg aatgtgagtc atacttagtc gctttgattt ctataaattt atagttattt
   149041 ccataatata ccttggcatt tttagaaaca ttgcttatct ttccaagaat ttcaaagtgt
   149101 ccatctttag atgggcttag aacaccataa atttttgatt ttatttcgtc aaatttttca
   149161 gtttcatatt ctagagcact ttcatcttca taggcagtta tatttccttt atcgtcatat
   149221 ttataatcaa gttctactgt tctttttcca ccagttacaa agtcgtcttc ttccttatat
   149281 ttctttttaa tgagtttctt taggtcttta ttttcaaagt ctctaattgt tgaaatattt
   149341 ctatcaatag taaaactaga tttttcttta atagactctt cattttcttg atgatgatgt
   149401 tctaccccag ttgtatcttt ttttagacta ccctcttttc catttcctaa atttttaaat
   149461 ttagattctg caatctcgcc aagcttttga tatttagatg aatcttgatc aggatctact
   149521 agataatagg aaatcatccc cttttcatca gcctgattag caaatttaat tctatgaatc
   149581 tttgtgaaat tgctagaacc atctaatgca atgacttcaa tgatttttcc ccttaaatct
   149641 cccgcacctt taatttcata aatggtattt ccgtctttgt caagttttct atttcttcct
   149701 tgaccctcac ctgcgtaagt tacttcaaga tttttttcaa cctctccatc ttcattaaca
   149761 agagcggcgc cagcatacca aacttcgttc gcaatctcgt caaatttttc aggatgttct
   149821 ttttgatctc tcgcaaatag cgtttcattc ttatactgat cttttacctt atgataagta
   149881 tcctttgtaa tcaacttaat tttttcagga tttgaaaaat caaccgaaac aatcttaggg
   149941 gcggtgttat caatttttac aggaatatag gaaacctgcc atgggtaatc tttagttaat
   150001 ctatatttaa atttatagaa atattgacct tccgcaatcg gttcaaattg acctcttatc
   150061 ttagtagcag gatcttgatt atccttactt tctggtgcat tttcttctct acctctagga
   150121 ttatagatga gtccatccca cttcaagtca ccccaaactt ttagtttaga tgatttgatt
   150181 ccctttgcat cattgctttt agaatttaaa attcctctaa taaagtgttc tctcgaaatg
   150241 acttttaagt ctctttgatt ttctccctct ttatttgtat ttactattga aatcaatcct
   150301 tcttctgcac ttcttaatac aagtggagaa ggtgttaatc ctctttcaag ttgagcatct
   150361 tgaggatttc catttgaatc taaaggataa atgttagcaa tcttagaacc acttgatgat
   150421 ggagcgttga tcccttggtt attgaaagca aataattctg gattttgatc cagggatgtt
   150481 gtatttttat cttttctatt ttgtataact cctgctggat taaatttatc tataccatgt
   150541 tctccaccaa ttcccttatt taaggttcct ggaattttcg gtttaccatc atcatcataa
   150601 cctcccagtg tttttgatct tgacccttct tcccaagccc atttatcaag gattggttcg
   150661 tggttccaat tcccagcaaa tcccattaga ggcatcgaca aagaaggttg gaagtttatt
   150721 ttcttcccgt tggagtttag agcttccatt tcttccactg actcaaaatg aataaatgat
   150781 tctacaaatt tatttttgtt tttggcctct ccaacattta taaccgcatt caaatcaaag
   150841 ctagaatttg cgcctatagt gaaagtatca tgctcaaatg tgatatttgc tcctttgact
   150901 ttttctgggt gaatttctgg aacaatttgc ttaccatctg gagatttttc atctttatat
   150961 gtttcatcaa gttttaatct gtcagttaaa gaatctgtag ttatcgctga tgctgaaact
   151021 ttaaaagtca aaggtctgtt tgatgtattg tgaagcttga ttgtaaagta ttttttatca
   151081 ccttttattt ctttaagaga aatggaacca tatgagttta ccaaaccttt agaatcagtg
   151141 tttttgaaag ttgctacaac ttcatttctc aaagcattgg ccacattaat taggcctgct
   151201 ccctgttgtc taggtgatgc aaagtattga cttttttctt tccaagaagt tgcatccatc
   151261 ataggtcgcg cagtattttg tagggcaatt tttgtaagac ttgtaagatc tattttgtca
   151321 tctcccttaa gatttttcaa tacaggtctt tcaagcattt cctttaattt cggtctaatc
   151381 aaaacagtag aagctgccac gattggagtc gccatactag ttcctgacat atagccataa
   151441 gttgatttgc cattaataac attaagcgtg gatttaatat ttttaccagg tgctgaaaca
   151501 tcgggtttta aaagtaaatc tattcttggc ccccaagatg tagatcctgc tggaacgatg
   151561 atatcttctt tatagagttc tttgtctgtg tcaggtgcaa acttaaagtc aatctctttt
   151621 tcgtcaccta cattcggttt gttggaatta aaactttcca tatcaattgg atagtattgc
   151681 tccaatttat ctttaaaatc ttctttatta tttcttttga cttcagtttt tttatcagga
   151741 ttaatcatgt tccatagctt tacaccatca tctcctgaaa ttgaaaacac ttgactttta
   151801 gtaccttcat ccgcttcata tcccatagct ggaagctctg tccaattatc tctattgtag
   151861 taatttacag tatttacaac cataatggcg cgtgcaccct tatccatagc ttttttaaaa
   151921 gcatttttta aatcctttgt ataaattcta tccattactg caattttgcc cctaagatcc
   151981 aaacctatca aatcttggtc ttgccccttg cctatatata caaattttaa tttactagga
   152041 gcttttgttc catcttcatt tgttgtgatt ttattcttat cgaaaaaggc ccctatattt
   152101 ctgtatttaa aactttctcc acctatgtta actttatcaa actcaactgt ttgattttta
   152161 gcagaagcga ccgctatcgc atcttcatgt gctgcagttc gtgttacatt tccagtgtcg
   152221 gtcattttca gatgattatt tgctactaaa tcccatgaag aacttgaagc agaagtcgca
   152281 tagttacccg tagcgacaac cattggaatg cctgcttttc ttaatgcccg aatagcttgc
   152341 caatatttct cacctacaag acctgttcct gtaaaaccag atgataccga aacaacatca
   152401 acgttgtgtt tgatagaatc ttcaatagca tgaaacattg tttcatcacc cgcaaaccca
   152461 gatcctgcgt cagaatacat tttgtaagag aaaatttgtg cattaggtgc aattccatct
   152521 atgccgttaa agtttttgat gtcttgttca gtatcatttc cagcaagaat ccctgcaata
   152581 tgcatcccat gtgggtcaaa ataatccctt ccatcatcat atttttctac agtgattttg
   152641 ccaccattat aataattgaa cgcatgaggg attttatcac tcaaccaata atttttatca
   152701 gtgcctttta agtcttcttt tttaaatctc attgaggctt tggcatcatc atcgattctc
   152761 atagccttat gtctataatc tgttccagta tcgatatttg aaatgaccat acctctacca
   152821 tcaaaatttt tcccaaacgg agcattgata gactttaggt aatcaatagc ttcctcaact
   152881 ccaatttcct ttctggcatg attcatcatg ggttggactt tttgtgccct ttcaaccgat
   152941 gaaatacctt ctatttgttt aattttgtcc aagttatctg gagttgtttc tatggcacta
   153001 ccattaaaaa ttctatcata agtatataaa acttttgtat tcttaagact ggatagttcc
   153061 ttgattgctt tttctccaga ttctttatct ttaaattcag caatatagac aactttatct
   153121 tcttttttgg gattttctgt gtttttattc acaaatgagt ccgtatgatc tccttgggat
   153181 ttattggaat tttcttcttt gatttttgct tcttcattgc tagttttagt gtctatcaca
   153241 ggatttttac taacaacttc tttttcctca ataattgttg ttttcttttc ttcagtatcc
   153301 tgtgaagttt ccatagcact atggatatct tcatgtttct ctttattttc tgctactttt
   153361 tctttatcag agatgcttaa agcatcttca gagctagatg tgtctgctaa gactacctca
   153421 ttaggggcat aggctgctaa aataactgca gctgtggtta atgacaatac tgtacttttt
   153481 ttcattttaa ttccttacat atttatataa cttccaatag ataataaact ttaactttgc
   153541 tagcctttgt tataaaaagt tttactaagt attatctagg aaatagagta gtacatttat
   153601 atataattgt tatctctcta taaaaacagt atatcattta aaaaaattta agtcaaaaaa
   153661 attaacatgc attaatttat tttttagcac acgttaaaaa ataagatta
//
LOCUS       DBEJAU010000002        75482 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC323 isolate 683620
            SAMN38261939-rid24807223.denovo.002, whole genome shotgun sequence.
ACCESSION   DBEJAU010000002 DBEJAU010000000
VERSION     DBEJAU010000002.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261939
            Sequence Read Archive: SRR26833919
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 75482)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 75482)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576303.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576303.1
            Genome Coverage       :: 154x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/19/2025 01:05:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,121
            CDSs (total)                      :: 2,078
            Genes (coding)                    :: 1,943
            CDSs (with protein)               :: 1,943
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 36
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 72 of 135
            Pseudo Genes (incomplete)         :: 63 of 135
            Pseudo Genes (internal stop)      :: 51 of 135
            Pseudo Genes (multiple problems)  :: 46 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..75482
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261939-rid24807223.denovo.002"
                     /strain="GPSC323"
                     /isolate="683620"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            173..2446
                     /locus_tag="ACL29Z_000152"
     CDS             173..2446
                     /locus_tag="ACL29Z_000152"
                     /EC_number="3.4.14.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008239 - dipeptidyl-peptidase activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Xaa-Pro dipeptidyl-peptidase"
                     /protein_id="HGR0068535.1"
                     /translation="MRFNQYSYINFPKENVLSELKKCGFDLQNTANHKDSLETFLRRF
                     FFTYQDTNYPLSILAADKKTDLLTFFQSEDELTADIFYTVAFQLLGFSYLVDFEDSDV
                     FRKETGFPIIYGDLIENLYQLLNTRTKKGNTLIDQLVSDGLIPEDNDYHYFNGKSLAT
                     FSNQDVIREVVYVESRVDTDQKGLSDLVKVSIIRPRFDGKIPAIMTASPYHQGTNDKA
                     SDKALYKMEGELEVKLPHKIELEKPQLNLVQPQGKAELIAEAEEKLTHINSSYTLNDY
                     FLPRGFANLYVSGVGTKDSTGFMTNGDYQQIEAYKNVIDWLNGRCRAFTDHTRQCQVK
                     ADWSNGKVATTGLSYLGTMSNGLATTGVDGLEVIIAEAGISSWYNYYRENGLVTSPGG
                     YPGEDFDSLAELTYSRNLLAGDYIRGNEAHQADLEKVKAQLDRKTGDYNQFWHDRNYL
                     LNAHKVKAEVVFTHGSQDWNVKPLHVYQMFHALPTHIHKHLFFHNGAHVYMNNWQSID
                     FRESINALLTKKLLGQETDFQLPTVIWQDNTAPQTWLSLDNFGGQENCETFSLGQEEQ
                     AIQNQYPDKDFERYGKTYQTFNTELYQGKANQITINLPVTKDLHLNGRAQLNLRIKSS
                     TNKGLLSAQLLEFGQKKYLQPYPAILSARTIDNGRYHMLENLCELPFRPEAQRVVTKG
                     YLNLQNRNDLLLVEDITADEWMDVQFELQPTIYKLKEGDTLRLVLYTTDFEITIRDNT
                     DYHLTVDLAQSMLTLPC"
     gene            2463..2933
                     /locus_tag="ACL29Z_000153"
     CDS             2463..2933
                     /locus_tag="ACL29Z_000153"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001043003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine repressor"
                     /protein_id="HGR0068536.1"
                     /translation="MNKSEHRHQLIRALITKNKIHTQAELQALLAENDIQVTQATLSR
                     DIKNMNLSKVREEDSAYYVLNNGSISKWEKRLELYMEDALVWMRPVQHQVLLKTLPGL
                     AQSFGSIIDTLSFPDAIATLCGNDVCLIICEDADTAQKCFEELKKFAPPFFFEE"
     gene            complement(3050..3205)
                     /locus_tag="ACL29Z_000154"
     CDS             complement(3050..3205)
                     /locus_tag="ACL29Z_000154"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0068537.1"
                     /translation="MKIKEQTRKLAAGCSKHCFEVVDETDEVSNHTYGKATLTRIEEI
                     FEEYKSS"
     gene            complement(3476..6826)
                     /locus_tag="ACL29Z_000155"
     CDS             complement(3476..6826)
                     /locus_tag="ACL29Z_000155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000526318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase family protein"
                     /protein_id="HGR0068538.1"
                     /translation="MGNFSFLLKNDEYESFSKPCIEAENMIATSTVATAFMARRALEQ
                     AVHWIYSHDSYLEAPYRATLSSLVWDDDFRDIVDSELHKQIVLLIRWGNHAAHGGEIK
                     EREAILALHHLYQFVNFIDYCYSNEFVERYFDEKCLPLSANIKYRETPQSMIKLQDSL
                     PELPDFHEQMAAQSVEVQETYTEKRETAAQRQDVPFHIDQLSEAETRKLFIDIDLRLA
                     GWIFEENCRVEIAVDGLKHGSGIGYCDYVLYGKNGKILAIVEAKKASVNPEVGEVQVK
                     EYAEALEKHIGYQPICFITNGLKHYILDGPNRRQIAGFYSQEELQLVMDRRHLQKPLE
                     DISSKIRDDISGRHYQKHAIASVCEAFSNHRRQALLVMATGAGKTRTAVSLVDILSRH
                     NWVKNVLFLADRTSLVKQAYDSFRKLLPDLSVCNFLEDKEGAQSSRMVFSTYPTMIGA
                     ISGQEEVNQRPFTVGHFDLIIIDESHRSIYQKYKSIFDYFDARIVGLTATPRQDLDKN
                     TYGFFNLENGVPTYAYDLEEAVKDGYLVAYHSIETKLKLPTDGLHYDDLSEEEKEHFD
                     SKFEDDSCEKDIDGSVFNSFIFNKSTVEIVLNELMTRGIQTASGDEIGKTIIFAKNHD
                     HAEYIRGIFNNRYPEKGSDYAQVIDYSIKHYQTLIDDFKIKEKYPQIAISVDMLDTGI
                     DVPEVVNLVFFKKVRSKTKFWQMIGRGTRLCKDLFGPEQDKENFLVFDYGDNFDYFRA
                     DPRDGEGRHIVSLTQRLFNIKVDLIRELQGLQYQEDQFARAYRQQLVSELQGRIESLN
                     ELDFRVRMVLDTVYSYRKLESWQNLTAVTSETIQKNLSPLLFDEDKEDEMARRFDLWL
                     LHIQLGQLTAKSSTVHISQVMKTARALSAIGNIPQVFEQAEIIRKVQEPEFWKEVNLS
                     DLEKIRLAIRDLLQFLDKTDRKPYYVNFEDRILSTVHETTAFLQVNDLRSYNEKVEHY
                     LKTHLDEESISKLYHNKKLTSDDMLALEKLLWEKLGSKADYQSHYENKAIPRLVREII
                     GLDRESANRIFSKFLSDENLNARQISFVKLIVDYIVENGFLETKVLTQEPFKSYGSVQ
                     LLFQHQLPVLRSIVQIIELINNRAGEAA"
     gene            complement(6856..7905)
                     /locus_tag="ACL29Z_000156"
     CDS             complement(6856..7905)
                     /locus_tag="ACL29Z_000156"
                     /EC_number="3.1.21.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000756118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006304 - DNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HGR0068539.1"
                     /translation="MKKVKLGQVATFINGYAFKPQDWSSEGKEIIRIQNLTKTSKGIN
                     YYSGTIDKKYIVEAGDILISWSGTLGVFQWCGRSAVLNQHIFKVVFDKIDIDKSYFKY
                     VVEKGLQDAVKHTHGSTMKHLTKKYFDNIIVPYTNLGEQQRIASELDLLSKLILRRQE
                     QLEELNLLVKSRFNEMFGDPLNNNKKFAVKTGQQCFKFSSGKFLDKHDRVFEGYPAYG
                     GNGIAWKSRKYLIDNPTIIIGRVGAYCGNVRTTHGKVWISDNAIYIKEFKNSDFNLVF
                     LLELMKVIDFSKFADFSGQPKITQKPLENQKYILPPLALQNEFADFVVQVDKSQFACE
                     IAIKVWRNSLKFSII"
     gene            complement(7939..8904)
                     /gene="xerA"
                     /locus_tag="ACL29Z_000157"
     CDS             complement(7939..8904)
                     /gene="xerA"
                     /locus_tag="ACL29Z_000157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000444451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008907 - integrase activity [Evidence
                     IEA];
                     GO_function: GO:0009037 - tyrosine-based site-specific
                     recombinase activity [Evidence IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific tyrosine recombinase/integron
                     integrase"
                     /protein_id="HGR0068540.1"
                     /translation="MESKVTIIMQEMLPLLNNEQLLALRESLEHHLVDGKKQQKYSNN
                     NLLQLFITAKQVEGCSSKTIRYYQRTIENLFNAIKESVTQLTTDDLRSYLANYQSEKD
                     CSKANLDNIRRILSSFFAWLEQEEYIIKNPIQRIKKIKTEQNVKETYTDEHLEIMRDN
                     CENLRDLAIIDLLASTGMRVGELVQLNRSDIDFENRECVVFGKGKKERPVYFDARTKI
                     HLRNYLNDRKDSHPALFVTLVGKAQRLGIAGVEIRLRKLGDKLGIQKVHPHKFRRTLA
                     TKAIDKGMPIEQVQKLLGHSKIDTTLAYAMVNQNNVKHSHQKFIS"
     gene            complement(9022..9435)
                     /locus_tag="ACL29Z_000158"
     CDS             complement(9022..9435)
                     /locus_tag="ACL29Z_000158"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000158364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system death-on-curing
                     family toxin"
                     /protein_id="HGR0068541.1"
                     /translation="MTIYLTEKQIEKINALAIQRYSPNEKIQTVSSSALNMIVNLPEQ
                     FVFGKSLYPTIFDKATILFVQLIKKHVFANANKRTAFFVLVKFLQLNGYRFSVTVEEA
                     VKMCVTIAVEALTDEKMTSYSKWVSEHSVREKVKK"
     gene            complement(9432..9668)
                     /locus_tag="ACL29Z_000159"
     CDS             complement(9432..9668)
                     /locus_tag="ACL29Z_000159"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000260605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AbrB family transcriptional regulator"
                     /protein_id="HGR0068542.1"
                     /translation="MVVKTRKQGNSITITIPSEFNIPSGVKYEAKLLQSGEIIFTPEE
                     LGQQVSYVSDDAFDLNLDKIFDEYDDVFKALVEK"
     gene            complement(9728..10849)
                     /locus_tag="ACL29Z_000160"
     CDS             complement(9728..10849)
                     /locus_tag="ACL29Z_000160"
                     /EC_number="3.1.21.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000756162.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006304 - DNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HGR0068543.1"
                     /translation="MKKVKLGEILSLKKGKKATVLAEQTTLSQRYIQIDDLRNNNNLK
                     FTESLNMTEALPDDILIAWDGANAGTVGYGLSGAVGSTITVLKKNERYKEKIISDYLG
                     VFLESKSQYLREHSTGATIPHLNKNILLDLQLELLGIEEQENIICILNTIKRLITKRK
                     FQLDELNLLVKSRFNEMFGENKIFESIDNLFDIIDGDRGKNYPKSDELFSEEYCLFLN
                     TKNVTKNGFSFDTKQFITKTKDKLLRKGKLERYDIVLTTRGTVGNVAYYDELIKYKHL
                     RINSGMVILRPKTPNLNQKFIIHVLRNNNYSRVISGSAQPQLPITKLKKILLPLPPLA
                     LQNEFADFVVQVDKSQLAIQKSLEELETLKKSLMQEYFG"
     gene            complement(10862..12355)
                     /locus_tag="ACL29Z_000161"
     CDS             complement(10862..12355)
                     /locus_tag="ACL29Z_000161"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000627753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0008170 - N-methyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="N-6 DNA methylase"
                     /protein_id="HGR0068544.1"
                     /translation="MITGELKNKIDQLWEILWTEGNANPLTNIEQLTYLLFMKDLDSV
                     ELGRESDAEFLGIPYEGVFPKDKPEYRWSTFKNIGDAQEVYRLMTQEIFPFIKNLKGD
                     TDDTAFSRYMREAIFQINKPATLQKAISILDVFPTRGLDVDFDNDKQSITDIGDIYEY
                     LLSKLSTAGKNGQFRTPRHIIDMMVELMQPTIKDIISDPAMGSAGFLVSASRYLKRKK
                     DEWETNTDNINHFHNQMFHGNDTDTTMLRLGAMNMMLHGVENPQISYLDSLSQDNEEA
                     DKYTLVLANPPFKGSLDYNSTSNDLLATVKTKKTELLFLSLFLRTLKPGGRAAVIVPD
                     GVLFGSSKAHKGIRQEIVENHKLDAVISMPSGVFKPYAGVSTAILIFTKTGNGGTDKV
                     WFYDMKADGLSLDDKRQPISDNDIPDIIERFHHLEKEAERQRTDQSFFVPVAEIKEND
                     YDLSINKYKEIEYEKVEYEPTEVILKKINDLEKEIQAGLAELEKLLK"
     gene            complement(12863..14029)
                     /locus_tag="ACL29Z_000162"
     CDS             complement(12863..14029)
                     /locus_tag="ACL29Z_000162"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001108652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-grasp domain-containing protein"
                     /protein_id="HGR0068545.1"
                     /translation="MNYLVISPYYPQNFQQFTIELANKGITVLGIGQESYEQLDEPLR
                     NSLTEYFRVDNLENIDEVKRAVAFLFYKHGPIDRIESHNEYWLELDATLREQFNVFGA
                     KPEDLKKTKYKSEMKKLFKKAGVPVVPGAVIKTEADVDQAVKEIGLPMIAKPDNGVGA
                     AATFKLETEDDINHFKQEWDHSTLYFFEKFVTSSEICTFDGLVDKDGKIVFSTTFDYA
                     YTPLDLMIYKMDNSYYVLKDMDPKLRKYGEAIVKEFGMKERFFHIEFFREGDDYITIE
                     YNNRPAGGFTIDVYNFAHSLDLYRGYAAIVAGEEFPASDFETQYCLATSRRANAHYVY
                     SEEDLLAKYSQQFKVKKVMPAAFAELQGDYLYMLTTPSRQEMDQMIADFGQRQE"
     gene            complement(14042..14781)
                     /locus_tag="ACL29Z_000163"
                     /pseudo
     CDS             complement(14042..14781)
                     /locus_tag="ACL29Z_000163"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000546805.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="esterase family protein"
     gene            complement(14803..15635)
                     /locus_tag="ACL29Z_000164"
                     /pseudo
     CDS             complement(14803..15635)
                     /locus_tag="ACL29Z_000164"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001076725.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
     gene            complement(15772..16986)
                     /gene="thiI"
                     /locus_tag="ACL29Z_000165"
     CDS             complement(15772..16986)
                     /gene="thiI"
                     /locus_tag="ACL29Z_000165"
                     /EC_number="2.8.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001200101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0140741 - tRNA-uracil-4 sulfurtransferase
                     activity [Evidence IEA];
                     GO_process: GO:0006400 - tRNA modification [Evidence IEA];
                     GO_process: GO:0009228 - thiamine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA uracil 4-sulfurtransferase ThiI"
                     /protein_id="HGR0068546.1"
                     /translation="MQYSEIMIRYGELSTKGKNRMRFINKLRNNISDVLSIYTQVKVT
                     ADRDRAHAYLNGADYTAVAESLKQVFGIQNFSPVYKVEKSVEVLKSSVQEIMRDIYKE
                     GMTFKISSKRSDHNFELDSRELNQTLGGAVFEAIPNVQVQMKSPDINLQVEIREEAAY
                     LSYETIRGAGGLPVGTSGKGMLMLSGGIDSPVAGYLALKRGVDIEAVHFASPPYTSPG
                     ALKKAQDLTRKLTKFGGNIQFIEVPFTEIQEEIKAKAPEAYLMTLTRRFMMRITDRIR
                     EVRNGLVIINGESLGQVASQTLESMKAINAVTNTPIIRPVVTMDKLEIIDIAQEIDTF
                     DISIQPFEDCCTIFAPDRPKTNPKIKNAEQYEARMDVEGLVERAVAGIMITEITPQAE
                     KDEVDDLIDNLL"
     gene            complement(16995..18137)
                     /locus_tag="ACL29Z_000166"
     CDS             complement(16995..18137)
                     /locus_tag="ACL29Z_000166"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000638948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase family protein"
                     /protein_id="HGR0068547.1"
                     /translation="MIYFDNSATTKPYPEALETYMQVASKILGNPSSLHRLGDQATRI
                     LDASRQQIADLIGKKSDEIFFTSGGTEGDNWVIKGVAFEKAQFGKHIIVSAIEHPAVK
                     ESALWLKSQGFEVDFAPVDKKGFVDVEVLAGLIRPDTILVSIMAVNNEIGSIQPIEAI
                     SEFLADKPTISFHVDAVQALAKIPTEKYLTERVDCATFSSHKFHGVRGVGFVYIKSGK
                     KITPLLTGGGQERDYRSTTENVAGIAATAKAFRLSMEKLDIFRSKTGQMKAVIRQALL
                     NYPDIFVFSDEEDFAPHILTFGIKGVRGEVIVHAFEDYDIFISTTSACSSKAGKPAGT
                     LIAMGVDKDKAKSAVRLSLDLENDMSQVEQFLTKLKLIYNQTRKVR"
     gene            18275..18712
                     /locus_tag="ACL29Z_000167"
     CDS             18275..18712
                     /locus_tag="ACL29Z_000167"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000073927.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF6556 family protein"
                     /protein_id="HGR0068548.1"
                     /translation="MSNYRRTSKPKTEHIKKGFTVFQKTITTIGSILGLITAGITIMN
                     ALDNNNKNTKKEPTTSQTTTFVKEIQKESPQENTTPNKENKTSQEKTQQEETPKSSVK
                     EEKKEEQKTSTQDSSTPAPTPSKPATENEKQSNTPTSENKTNQ"
     gene            complement(18757..21009)
                     /locus_tag="ACL29Z_000168"
     CDS             complement(18757..21009)
                     /locus_tag="ACL29Z_000168"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012512593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA translocase FtsK"
                     /protein_id="HGR0068549.1"
                     /translation="MERKEAIQRMLISLGIAILLIFAAFKLGAAGITLYNLIRLLVGS
                     LAYLAIFGLLIYLFFFKWIRKQEGLLSGFFTIFAGLLLIFEAYLVWKYGLDKSVLKGT
                     MAQVVTDLTGFRTTSFAGGGLIGVALYIPTAFLFSNIGTYFIGSILILVGSLLVSPWS
                     VYDIAEFFSRGFAKWWEGHERRKEERFVKQEEKARQKAEKEARLEQEETEKALLDLPP
                     VDMETGEILTEEAVQNLPPIPEEKWVEPEIILPQAELKFPEQEDDSDDEDVQVDFSAK
                     EALEYKLPSLQLFAPDKPKDQSKEKKIVRENIKILEATFASFGIKVTVERAEIGPSVT
                     KYEVKPAVGVRVNRISNLSDDLALALAAKDVRIEAPIPGKSLIGIEVPNSDIATVSFR
                     ELWEQSQTKAENFLEIPLGKAVNGTARAFDLSKMPHLLVAGSTGSGKSVAVNGIIASI
                     LMKARPDQVKFMMVDPKMVELSVYNDIPHLLIPVVTNPRKASKALQKVVDEMENRYEL
                     FAKVGVRNIAGFNAKVEEFNSQSEYKQIPLPLIVVIVDELADLMMVASKEVEDAIIRL
                     GQKARAAGIHMILATQRPSVDVISGLIKANVPSRVAFAVSSGTDSRTILDENGAEKLL
                     GRGDMLFKPIDENHPVRLQGSFISDDDVERIVNFIKAQADADYDESFDPGEVSENEGE
                     FSDGDAGGDPLFEEAKSLVIETQKASASMIQRRLSVGFNRATRLMEELEMAGVIGPAE
                     GTKPRKVLQQ"
     gene            complement(21146..23098)
                     /locus_tag="ACL29Z_000169"
     CDS             complement(21146..23098)
                     /locus_tag="ACL29Z_000169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000701424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022877 -
                     protein-N(PI)-phosphohistidine-fructose phosphotransferase
                     system transporter activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-specific PTS transporter subunit EIIC"
                     /protein_id="HGR0068550.1"
                     /translation="MKIQDLLRKDVMLLDLQATEKTAVIEEMIKSLVDHGYVTDFETF
                     KEGILAREALTSTGLGDGIAMPHSKNAAVKEATVLFAKSNKGVDYESLDGQATDLFFM
                     IAAPEGANDTHLAALAELSQYLMKDGFADKLRQATSADQVIELFDQALEKTEEPAQAL
                     ANNSGDFIVAVTACTTGIAHTYMAQEALQKVAAEMGVGIKVETNGASGVGNQLTGEDI
                     RKAKAVIIAADKAVEMDRFDGKPLINRPVADGIRKTEELINLALSGDAEIYRAANGAK
                     AATTSNEKQSLGGAFYKHLMSGVSQMLPFVIGGGIMIALAFLIDGALGVPNENLGNLG
                     SYHELASMFMKIGGAAFGLMLPVFAGYVAYSIAEKPGLVAGFVAGAIAKEGFAFGKIP
                     YAAGGEATSTLAGVSSGFLGALVGGFIAGALVLAIKKYVKVPRSLEGAKSILLLPLLG
                     TILTGFVMLAVNIPMAAINTAMNDFLGGLGGGSAVLLGIVLGGMMAVDMGGPVNKAAY
                     VFGTGTLAATVSSGGSVAMAAVMAGGMVPPLAIFVATLLFKDKFTKEERNSGLTNIIM
                     GLSFITEGAIPFGAADPARAIPSFILGSAVAGGLVGLTGIKLMAPHGGIFVIALTSNA
                     LLYLVSVLVGAIVSGVVYGYLRKPQA"
     gene            complement(23095..24006)
                     /gene="pfkB"
                     /locus_tag="ACL29Z_000170"
     CDS             complement(23095..24006)
                     /gene="pfkB"
                     /locus_tag="ACL29Z_000170"
                     /EC_number="2.7.1.56"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015605104.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008662 - 1-phosphofructokinase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="1-phosphofructokinase"
                     /protein_id="HGR0068551.1"
                     /translation="MIYTVTLNPSIDYIVRLDQVQVGSVNRMDSDDKFAGGKGINVSR
                     VLKRLDIPNTATGFIGGFTGKFITDTLAKEEIETRFVQVAEDTRINVKIKADQETEIN
                     GTGPTVEPAQLEELKDILSSLTAEDTVVFAGSSAKNLGNVIYKDLITLTRQTGAQVVC
                     DFEGQTLIDSLEYQPLLVKPNNHELGAIFGVELDSLDEIEKYARELLVKGAQNVIISM
                     AGDGALLVTSEGAYFAKPIKGTVKNSVGAGDSMVAGFTGEFVKSKDAVEAFKWGVACG
                     TATTFSDDLATAEFIKETYEKVEVEKR"
     gene            complement(24003..24743)
                     /locus_tag="ACL29Z_000171"
     CDS             complement(24003..24743)
                     /locus_tag="ACL29Z_000171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000920650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR family DNA-binding transcription
                     regulator"
                     /protein_id="HGR0068552.1"
                     /translation="MLKTERKQLILEELNQHHVVSLEKLVSLLETSESTVRRDLDELE
                     AENKLRRVHGGAELPHSLQEEETIQEKSVKNLQEKKLLAQKAASLIKEQDVIFIDAGT
                     TTAFLIHELVNKNITVVTNSIHHAAQLVEKQIPTVMVGGSVKMATDASIGGVALNQIN
                     QLHFDRAFIGMNGVDDGYYTTPDMEEGAVKRAILENAKQTYVLVDSSKIGQTCFAKVA
                     PLKRAIVITSQGHELLQAIKEKTEVIEV"
     gene            24905..24992
                     /locus_tag="ACL29Z_000172"
     tRNA            24905..24992
                     /locus_tag="ACL29Z_000172"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:24939..24941,aa:Ser,seq:gga)
     gene            complement(25071..26405)
                     /locus_tag="ACL29Z_000173"
     CDS             complement(25071..26405)
                     /locus_tag="ACL29Z_000173"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007521515.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Nramp family divalent metal transporter"
                     /protein_id="HGR0068553.1"
                     /translation="MSSHKKVSLSEINQSIDTPNNNHFWQNLNAFLGPGALVAVGYMD
                     PGNWITSVVGGASYKYSLLFVILISSLIAMQLQQMAGKLGIVTQMDLAQATAHHSPKW
                     LRYSLWVILELALMATDLAEVLGSAIALNLLFKIPIMIAILLTVLDVFLLLLLMKFGF
                     KKIEAIVTTLILTILAIFTYLVALSHPSFQGIVEGYLPNATLFESPLPGHESQLTLAL
                     GIVGATVMPHNLYLHSSLSQTRKINHKDKNDVRKAVRFMTWDSNLQLSLAFVVNSLLL
                     ILGAALFFGHASEISAFSQMYNALQDSTIAGAIASSTLSTLFALALLASGQNSTITGT
                     LTGQIVMEGFLHMRLPQWFIRLATRLFALLPVMIVAVLFGHQEKTLDQLLVYSQVFLS
                     IALPFSIFPLIYLTSKKSLMGEFTNAKWNTILGYIVSIILTILNVKLLFDIF"
     gene            complement(26711..27058)
                     /gene="ssrA"
                     /locus_tag="ACL29Z_000174"
     tmRNA           complement(26711..27058)
                     /gene="ssrA"
                     /locus_tag="ACL29Z_000174"
                     /product="transfer-messenger RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00023"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00023"
     gene            complement(27704..28813)
                     /gene="cozE"
                     /locus_tag="ACL29Z_000175"
     CDS             complement(27704..28813)
                     /gene="cozE"
                     /locus_tag="ACL29Z_000175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000489841.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell elongation protein CozE"
                     /protein_id="HGR0068554.1"
                     /translation="MFRRNKLFFWTTEILLLTIIFYLWRQMGSLINPFVSVLNTIMIP
                     FLLGGFLYYLTNPIVTFLNKVCKLNRLLGILITLCTLVWGMVIGVVYLLPILINQLSS
                     LIISSQTIYSRVQDLIIDLSNYPALQNLDVEATIQQLNLSYVDILQNILNSVSNSVGS
                     VLSALISTVLILIMTPVFLVYFLLDGHKFLPMLERTILKRDRLHIAGLLKNLNATIAR
                     YISGVSIDAIIIGCLAYIGYSIIGLKYALVFAIFSGVANLIPYVGPSIGLIPMIIANI
                     FTDPHRLLIAVIYMLVVQQVDGNILYPRIVGSVMKVHPITILVLLLLSSNIYGVVGMI
                     VAVPTYSILKEISKFLSRLYENHKIMKERERELAK"
     gene            28916..30157
                     /gene="pbp3"
                     /locus_tag="ACL29Z_000176"
     CDS             28916..30157
                     /gene="pbp3"
                     /locus_tag="ACL29Z_000176"
                     /EC_number="3.4.16.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-D-alanine carboxypeptidase PBP3"
                     /protein_id="HGR0068555.1"
                     /translation="MKKIFLTLLTVSLLGGASTAVAQDFTIAAKHAIAVEANTGKILY
                     EKDATQPVEIASITKLITVYLVYEALENGSITLSTPVDISDYPYQLTTNSEASNIPME
                     ARNYTVEELLEATLVSSANSAAIALAEKIAGSEKDFVDMMRAKLLEWGIQDATVVNTT
                     GLNNETLGDNIYPGSKKDEENKLSAYDVAIVARNLIKKYPQVLEITKKPSSTFAGMTI
                     TSTNYMLEGMPAYRGGFDGLKTGTTDKAGESFVGTTVEKGMRVITVVLNADHQDNNPY
                     ARFTATSSLMDYISSTFTLRKIVQQGDAYQDSKAPVQDGKEDTVTAVAPEDIYLIERV
                     GNQSSQSVQFTPDSKAIPAPLEAGTVVGHLTYEDKDLIGQGYITTERPSFEMVADKKI
                     EKAFFLKVWWNQFVRFVNEKL"
     gene            complement(30356..31768)
                     /gene="sufB"
                     /locus_tag="ACL29Z_000177"
     CDS             complement(30356..31768)
                     /gene="sufB"
                     /locus_tag="ACL29Z_000177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017769002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0016226 - iron-sulfur cluster assembly
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly protein SufB"
                     /protein_id="HGR0068556.1"
                     /translation="MAEERVEPKPIDLGEYKFGFHDDVEPVLSTGKGLNEGVIRELSA
                     AKGEPEWMLEFRLKSYETFKKMPMQTWGADLSEIDFDDLIYYQKPSDKPARSWDDVPE
                     KIKETFERIGIPEAERAYLAGASAQYESEVVYHNMKEEFQKLGIIFTDTDSALKEYPD
                     LFNQYFAKLVPPTDNKLAALNSAVWSGGTFIYVPKGVKVDIPLQTYFRINNENIGQFE
                     RTLIIVDEGASVHYVEGCTAPTYSSNSLHAAIVEIFALDGAYMRYTTIQNWSDNVYNL
                     VTKRAKAQKDATVEWIDGNLGAKTTMKYPSVYLDGEGARGTMLSIAFANAGQHQDTGA
                     KMIHNAPHTSSSIVSKSIAKGGGKVDYRGQVTFNKNSKKSVSHIECDTIIMDDLSASD
                     TIPFNEIHNSQVALEHEAKVSKISEEQLYYLMSRGLSESEATEMIVMGFVEPFTKELP
                     MEYAVELNRLISYEMEGSVG"
     gene            complement(31822..32262)
                     /gene="sufU"
                     /locus_tag="ACL29Z_000178"
     CDS             complement(31822..32262)
                     /gene="sufU"
                     /locus_tag="ACL29Z_000178"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005198 - structural molecule activity
                     [Evidence IEA];
                     GO_process: GO:0016226 - iron-sulfur cluster assembly
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly sulfur transfer protein
                     SufU"
                     /protein_id="HGR0068557.1"
                     /translation="MALSKLDSLYMAVVADHSKNPHHQGKLEDAEQTSLNNPTCGDVI
                     NLSVKFDAEDRLEDIAFLNSGCTISTASASMMTDAVLGKTKQEILELATIFSEMVQGQ
                     KDERQGQLGDAAFLSGVAKFPQRIKCATLAWNALKKTIENQEKQ"
     gene            complement(32249..33475)
                     /locus_tag="ACL29Z_000179"
     CDS             complement(32249..33475)
                     /locus_tag="ACL29Z_000179"
                     /EC_number="2.8.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000887707.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA];
                     GO_function: GO:0031071 - cysteine desulfurase activity
                     [Evidence IEA];
                     GO_process: GO:0006534 - cysteine metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase"
                     /protein_id="HGR0068558.1"
                     /translation="MLDVEAIRKDFPILDQIVNDEPLVYLDNAATTQKPLVVLKAINS
                     YYEQDNANVHRGVHTLAERATASYEAARETIRKFINAGSTKEVLFTRGTTTSLNWVAR
                     FAEEILAEGDQVLISVMEHHSNIIPWQEACRKTGAELVYVYLKDGALDMEDLRAKLTD
                     KVKFVSLAHASNVLGVVNPIKEITQLAHQVGAIMVVDGAQSTPHMKIDVQDLDLDFFA
                     FSGHKMAGPTGIGVLYGKEKYLEQMSPVEFGGEMIDFVYEQFASWKELPWKFEAGTPN
                     MAGAIGLATAVDYLEKIGMDAVEAHEQELIAYVYPKLQAIEGLTIYGSQDLAQRSGVI
                     AFNLGDLHPHDLATALDYEGVAVRAGHHCAQPLLQYLEVPATARASFYIYNTKADCDK
                     LVDALQKTKEFFNGTF"
     gene            complement(33486..34748)
                     /gene="sufD"
                     /locus_tag="ACL29Z_000180"
     CDS             complement(33486..34748)
                     /gene="sufD"
                     /locus_tag="ACL29Z_000180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0016226 - iron-sulfur cluster assembly
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly protein SufD"
                     /protein_id="HGR0068559.1"
                     /translation="MTRENIKLFSEMHAEPSWLADLRQKAFDKIETLELPVIERVKFH
                     RWNLGDGTITENEPSANVPDFTALDHHLKLVQVGTQTVFEQTPVELAEQGVVFTDFHS
                     ALEEIPELIEEFFMSSVKYDDDKLAAYHTAYFNSGAVLYIPDNVEITEPIEGIFYQDS
                     DSNVPFNKHIMIIAGKNSKINYLERLESRGEGSAKATANITVEVIARSGAQVKFAAID
                     RLGENVTAYISRRGKLGNDASIDWAIGVMNEGNVVADFDSDLIGNGSHADLKVVALSS
                     GRQVQGIDTRVTNYGCNSIGNILQHGVILEKATLTFNGIGHIIKGAKGADAQQESRVL
                     MLSDQARSDANPILLIDENDVTAGHAASIGQVDPEDMYYLMSRGLDKATAERLVVRGF
                     LGSVIVEIPVKEVRDEMIATIEEKLSKR"
     gene            complement(34776..35546)
                     /gene="sufC"
                     /locus_tag="ACL29Z_000181"
     CDS             complement(34776..35546)
                     /gene="sufC"
                     /locus_tag="ACL29Z_000181"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000114488.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0016226 - iron-sulfur cluster assembly
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly ATPase SufC"
                     /protein_id="HGR0068560.1"
                     /translation="MSVLEIKDLHVEIEGKEILKGVNLTLKTGEIAAIMGPNGTGKST
                     LSAAIMGNPNYEVTKGEVLFDGVNILELEVDERARMGLFLAMQYPSEIPGITNAEFLR
                     AAMNAGKEDDEKISVREFITKLDEKMELLNMKEEMAERYLNEGFSGGEKKRNEILQLL
                     MLEPTFALLDEIDSGLDIDALKVVSKGVNAMRGEGFGAMIITHYQRLLNYITPDVVHV
                     MMEGRVVLSGGPELAARLEREGYAKLAEELGYDYKEEL"
     gene            complement(35696..35890)
                     /locus_tag="ACL29Z_000182"
     CDS             complement(35696..35890)
                     /locus_tag="ACL29Z_000182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001041548.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3272 domain-containing protein"
                     /protein_id="HGR0068561.1"
                     /translation="MNKQQFIIMALFTAAETYFFNESWMTGRYIMAAFWAILLFRNFR
                     VSYVMGKIVDVIDQHFNRKD"
     gene            complement(35918..37573)
                     /gene="dnaX"
                     /locus_tag="ACL29Z_000183"
     CDS             complement(35918..37573)
                     /gene="dnaX"
                     /locus_tag="ACL29Z_000183"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000283769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009360 - DNA polymerase III complex
                     [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit gamma/tau"
                     /protein_id="HGR0068562.1"
                     /translation="MYQALYRKYRSQNFSQLVGQEVVAKTLKQAVEQEKISHAYLFSG
                     PRGTGKTSVAKIFAKAMNCPNQVGGEPCNNCYICQAVTDGSLEDVIEMDAASNNGVDE
                     IREIRDKSTYAPSLARYKVYIIDEVHMLSTGAFNALLKTLEEPTQNVVFILATTELHK
                     IPATILSRVQRFEFKSIKTQDIKEHIHYILEKENISSEPEAVEIIARRAEGGMRDALS
                     ILDQALSLTQGNELTTAISEEITGTISLSALDDYVAALSQQDVPKALSCLNLLFDNGK
                     SMTRFVTDLLHYLRDLLIVQTGGENTHHSSVFVENLALPQKNLFEMIRLATVSLADIK
                     SSLQPKIYAEMMTVRLAEIKPEPALSGAVENEIATLRQEVARLKQELSNVGAVPKQVA
                     PAPSRPATGKTVYRVDRNKVQSILQEAVENPDLARQNLIRLQNAWGEVIESLGGPDKA
                     LLVGSQPVAANEHHAILAFESNFNAGQTMKRDNLNTMFGNILSQAAGFSPEILAISME
                     EWKEVRAAFSAKAKSSQTEKEVEESLIPEGFEFLADKVKVEED"
     gene            complement(37573..38070)
                     /locus_tag="ACL29Z_000184"
     CDS             complement(37573..38070)
                     /locus_tag="ACL29Z_000184"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000920162.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005515 - protein binding [Evidence IEA];
                     GO_function: GO:0033745 - L-methionine-(R)-S-oxide
                     reductase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GAF domain-containing protein"
                     /protein_id="HGR0068563.1"
                     /translation="MLKSEKQSRYQMLNEELSFLLEGETNVLANLSNASALIKSRFPN
                     TVFAGFYLFDGKELVLGPFQGGVSCIRIALGKGVCGEAAHFQETVIVGDVTTYLNYIS
                     CDSLAKSEIVVPMMKNGQLLGVLDLDSSEIEDYDAMDRDYLEQFVAILLEKTTWDFTM
                     FEEKS"
     gene            complement(38156..39358)
                     /gene="rpsA"
                     /locus_tag="ACL29Z_000185"
     CDS             complement(38156..39358)
                     /gene="rpsA"
                     /locus_tag="ACL29Z_000185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002897515.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S1"
                     /protein_id="HGR0068564.1"
                     /translation="MNEFEDLLNSVSQVETGDVVSAEVLTVDATQANVAISGTGVEGV
                     LTLRELTNDRDADINDFVKVGEVLDVLVLRQVVGKDTDTVTYLVSKKRLEARKAWDKL
                     VGREEEVVTVKGTRAVKGGLSVEFEGVRGFIPASMLDTRFVRNAERFVGQEFDTKIKE
                     VNAKENRFILSRREVVEAATAAARAEVFGKLAVGDVVTGKVARITSFGAFIDLGGVDG
                     LVHLTELSHERNVSPKSVVTVGEEIEVKILDLNEEEGRVSLSLKATVPGPWDGVEQKL
                     AKGDVVEGTVKRLTDFGAFVEVLPGIDGLVHVSQISHKRIENPKEALKVGQEVQVKVL
                     EVNADAERVSLSIKALEERPVQEEGQKEEKRAARPRRPRRQEKRDFELPETQTGFSMA
                     DLFGDIEL"
     gene            complement(39520..39591)
                     /locus_tag="ACL29Z_000186"
     tRNA            complement(39520..39591)
                     /locus_tag="ACL29Z_000186"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(39557..39559),aa:Gln,seq:ttg)
     gene            complement(39601..39681)
                     /locus_tag="ACL29Z_000187"
     tRNA            complement(39601..39681)
                     /locus_tag="ACL29Z_000187"
                     /product="tRNA-Tyr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(39645..39647),aa:Tyr,seq:gta)
     gene            complement(39731..39961)
                     /locus_tag="ACL29Z_000188"
     CDS             complement(39731..39961)
                     /locus_tag="ACL29Z_000188"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000037109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2969 domain-containing protein"
                     /protein_id="HGR0068565.1"
                     /translation="MSKKDKKIEIQVADAKVNVGKDSFEGYTLTIGKKVIGEIAELDG
                     QFAIIKNGNVDSFYKKLEKAVEILIENYNLAK"
     gene            complement(40129..40773)
                     /gene="pcp"
                     /locus_tag="ACL29Z_000189"
     CDS             complement(40129..40773)
                     /gene="pcp"
                     /locus_tag="ACL29Z_000189"
                     /EC_number="3.4.19.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005829 - cytosol [Evidence IEA];
                     GO_function: GO:0008234 - cysteine-type peptidase activity
                     [Evidence IEA];
                     GO_function: GO:0016920 - pyroglutamyl-peptidase activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyroglutamyl-peptidase I"
                     /protein_id="HGR0068566.1"
                     /translation="MKILVTGFNPFGGEKINPALEAVKLLPSEINGAEVRWVEIPTVF
                     YKSSEVLEAEILRYQPDAVLCIGQAGGRTGLTPERVAINQDDARIPDNEGNQPIDTPI
                     RIDGASAYFSSLPIKAMVQAIKKQGLPAVVSNSAGTFVCNHLMYQALYLVDKKFPNMR
                     AGFMHIPYMMEQVVNKPNTAGMSLCDIVRGIEVAIEAIVDYKDKDLQLVGGETH"
     gene            complement(40788..41711)
                     /locus_tag="ACL29Z_000190"
     CDS             complement(40788..41711)
                     /locus_tag="ACL29Z_000190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000137265.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SP_0859 family membrane protein"
                     /protein_id="HGR0068567.1"
                     /translation="MTELAKQLLELTYIVIGCQFLHTAYCSYKDKTNPVRLGTSAFWT
                     LLSITFIGGSYMPNMSIGIIVILLSLLTLFKQVRIGTLPSLDEMKANIESNRLKNKIF
                     IPVMLMAILALVLAQMIPEFSKISISLAALFATISVLVITNSHPKSLLSENNRMTQQV
                     STSGIVPQLLGALGAIFTVAGVGDVISHLISGIVPSDSRFIGVLAYVLGMVLFTMIMG
                     NAFAAFTVITAGVGVPFVFALGANPIVAGALAMTAGYCGTLLTPMAANFNALPAALMD
                     MKDQNGVIKAQAGVALVMIVIHIFLMYFLAF"
     gene            complement(41708..42397)
                     /locus_tag="ACL29Z_000191"
     CDS             complement(41708..42397)
                     /locus_tag="ACL29Z_000191"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000454809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SP_0858 family membrane protein"
                     /protein_id="HGR0068568.1"
                     /translation="MEWIRLIGIAIIVVGFILKFDTIATVVLAGLVTALVSGVSLVEF
                     LEILGKEFSNQRVLTIFMVTLPLVGLSETFGLKQRSIDLIRKIKGLTVGNFYTVYFFI
                     RELAGFFSIRLGGHPQFVRPLVQPMGEAAAESQLGRKLTEVEDETIKARAAANENFGN
                     FFAQNTFVGAGGVLLIGGTLDQLGYESNYAGIASTSIIVAVITLIVVGIYNYLFDKKL
                     ISKKTRGGEQK"
     gene            complement(42462..43166)
                     /locus_tag="ACL29Z_000192"
     CDS             complement(42462..43166)
                     /locus_tag="ACL29Z_000192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001810388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide ABC transporter substrate-binding
                     protein"
                     /protein_id="HGR0068569.1"
                     /translation="MVLSTSAILVACGKTDKEADAPTTFSYVYAVDPASLGYSIATRT
                     SRTDVIGNVIDGLMENDKYGNVAPSQKDYDLNSTGWAPSYQDPASYLNIMDPKSGSAM
                     KHLGITKGKDKDVVAKPGLDKYKKLLEDAVSETTDLEKRYEKYAKAQAWSTDSSLLMP
                     TASSGGSPVVSNVVPFSKPYSQVGIKGEPYIFKGMKLQKDIVTTKEYNEVFKKWQKEK
                     LESNSKYQKELEKYIK"
     gene            complement(43222..44244)
                     /locus_tag="ACL29Z_000193"
     CDS             complement(43222..44244)
                     /locus_tag="ACL29Z_000193"
                     /EC_number="2.6.1.42"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004084 - branched-chain-amino-acid
                     transaminase activity [Evidence IEA];
                     GO_process: GO:0009081 - branched-chain amino acid
                     metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid aminotransferase"
                     /protein_id="HGR0068570.1"
                     /translation="MTVTIDWENLGFSYMKLPYRYLAHFKNGQWDQGELTEDATLHIS
                     ESSPSLHYGQQAFEGLKAYRTKDGSVQLFRPDENAKRLQRTCDRLLMPQVPTDMFVEA
                     CKAVVRANEEYVPPYGIGGTLYLRPLLIGVGDIIGVKPAEEYIFTIFAMPVGNYFKGG
                     LVPTNFLIQDEYDRAAPNGTGAAKVGGNYAASLLPGKMAKSRHFSDVIYLDPSTHTKI
                     EEVGSANFFGITADNEFVTPLSPSILPSITKYSLLYLAEHRLGLTPIEGDVPIDNLDR
                     FVEAGACGTAAVISPIGGIQHGDDFHVFYSETEVGPVTRKLYNELTGIQFGDIEAPEG
                     WIVKVD"
     gene            complement(44374..46845)
                     /gene="parC"
                     /locus_tag="ACL29Z_000194"
     CDS             complement(44374..46845)
                     /gene="parC"
                     /locus_tag="ACL29Z_000194"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012512618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005694 - chromosome [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003918 - DNA topoisomerase type II
                     (double strand cut, ATP-hydrolyzing) activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006265 - DNA topological change [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase IV subunit A"
                     /protein_id="HGR0068571.1"
                     /translation="MSNIQNMSLEDIMGERFGRYSKYIIQDRALPDIRDGLKPVQRRI
                     LYSMNKDGNTFDKSYRKSAKSVGNIMGNFHPHGDSSIYDAMVRMSQNWKNREILVEMH
                     GNNGSMDGDPPAAMRYTEARLSEIAGYLLQDIEKNTVPFAWNFDDTEKEPTVLPAAFP
                     NLLVNGSTGISAGYATDIPPHNLAEVIDAAIYMIDHPTAKIDKLMEFLPGPDFPTGAI
                     IQGRDEIKKAYETGKGRVVVRSKTEIEKLKGGKEQIVITEIPYEINKANLVKKIDDVR
                     VNNKVAGIAEVRDESDRDGLRIAIELKKDANTELVLNYLFKYTDLQINYNFNMVAIDN
                     FTPRQVGIVPILSSYIAHRREVILARSRFDKEKAEKRLHIVEGLIRVISILDEVIALI
                     RASENKADAKENLKVSYDFTEEQAEAIVTLQLYRLTNTDVVVLQEEEAELREKIAMLA
                     AIIGDERTMYNLMKKELREVKKKFATPRLSSLEDTAKAIEIDTASLIAEEDTYVSVTK
                     AGYIKRTSPRSFAASTLEEIGKRDDDRLIFVQSAKTTQHLLMFTSLGNVIYRPIHELA
                     DIRWKDIGEHLSQTITNFETNEEILYVEVLDQFDDATTYFAVTRLGQIKRVERKEFTP
                     WRTYRSKSVKYAKLKDDTDQIVAVAPIKLDDVVLVSQNGYALRFNIEEVPVVGAKAAG
                     VKAMNLKEDDVLQSGFICNTSSFYLLTQRGSLKRVSIEEILATSRAKRGLQVLRELKN
                     KPHRVFLAGAVAEQGFVGDFFSTEVDVNDQTLLVQSNKGTIYESRLQDLNLSERTSNG
                     SFISDTISDEEVFDAYLQEVVTEDK"
     gene            complement(47046..47250)
                     /locus_tag="ACL29Z_000195"
                     /pseudo
     CDS             complement(47046..47250)
                     /locus_tag="ACL29Z_000195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009014166.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="N-6 DNA methylase"
     gene            complement(47265..49208)
                     /gene="parE"
                     /locus_tag="ACL29Z_000196"
     CDS             complement(47265..49208)
                     /gene="parE"
                     /locus_tag="ACL29Z_000196"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522163.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005694 - chromosome [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003918 - DNA topoisomerase type II
                     (double strand cut, ATP-hydrolyzing) activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006265 - DNA topological change [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase IV subunit B"
                     /protein_id="HGR0068572.1"
                     /translation="MSKKEININNYNDDAIQVLEGLDAVRKRPGMYIGSTDGAGLHHL
                     VWEIVDNAVDEALSGFGDRIDVTINKDGSLTVQDHGRGMPTGMHAMGIPTVEVIFTIL
                     HAGGKFGQGGYKTSGGLHGVGSSVVNALSSWLEVEITRDGAVYKQRFENGGKPVTTLK
                     KIGTAPKSKTGTKVTFMPDATIFSTTDFKYNTISERLNESAFLLKNVTLSLTDKRTDE
                     AIEFHYENGVQDFVSYLNEDKEILTPVLYFEGEDNGFQVEVALQYNDGFSDNILSFVN
                     NVRTKDGGTHETGLKSAITKVMNDYARKTGLLKEKDKNLEGSDYREGLAAVLSILVPE
                     EHLQFEGQTKDKLGSPLARPVVDGIVADKLTFFLMENGELASNLIRKAIKARDAREAA
                     RKARDESRNGKKNKKDKGLLSGKLTPAQSKNPAKNELYLVEGDSAGGSAKQGRDRKFQ
                     AILPLRGKVINTAKAKMADILKNEEINTMIYTIGAGVGADFSIEDANYDKIIIMTDAD
                     TDGAHIQTLLLTFFYRYMRPLVEAGHVYIALPPLYKMSKGKGKKEEVAYAWTDGELEE
                     LRKQFGKGATLQRYKGLGEMNADQLWETTMNPETRTLIRVTIEDLARAERRVNVLMGD
                     KVEPRRKWIEDNVKFTLEEATVF"
     gene            49344..49985
                     /gene="plsY"
                     /locus_tag="ACL29Z_000197"
     CDS             49344..49985
                     /gene="plsY"
                     /locus_tag="ACL29Z_000197"
                     /EC_number="2.3.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000628793.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0008374 - O-acyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0006654 - phosphatidic acid biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol-3-phosphate 1-O-acyltransferase PlsY"
                     /protein_id="HGR0068573.1"
                     /translation="MITIVLLILAYLLGSIPSGLWIGQVFFQINLREHGSGNTGTTNT
                     FRILGKKAGMATFVIDFFKGTLATLLPIIFHLQGVSPLIFGLLAVIGHTFPIFAGFKG
                     GKAVATSAGVIFGFAPIFCLYLAIIFFGALYLGSMISLSSVTASIAAVIGVLLFPLFG
                     FILSNYDSLFIAIILALASLIIIRHKDNIARIKNKTENLVPWGLNLTHQDPKK"
     gene            complement(50028..51251)
                     /locus_tag="ACL29Z_000198"
                     /pseudo
     CDS             complement(50028..51251)
                     /locus_tag="ACL29Z_000198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611512.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
     gene            complement(51336..52292)
                     /locus_tag="ACL29Z_000199"
     CDS             complement(51336..52292)
                     /locus_tag="ACL29Z_000199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000060306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HGR0068574.1"
                     /translation="MSIITLLPLLVSSMLIYSAPLIFTSIGGVFSERGGVVNVGLEGI
                     MVMGAFSGVVFNLEFAEQFGAATPWLSLLVAGLVGSVFSIIHAAATVHFRADHVVSGT
                     VLNLMAPALAVFLVKVLYNKGQTDNLSQTFGRFDFPVLANIPVIGDIFFKSTSLLGYL
                     AIAFSFLAWFILFKTQFGLRLRSVGEHPQAADTLGINVYKMRYLGIIISGFLGGIGGA
                     IYAQSISVNFSVTTIVGPGFIALAAMIFGKWNPIGAMLSSLFFGLSQSLAVIGSQLPF
                     LQGVPAVYLQIAPYVLTILVLAAFFGKAVAPKADGINYIKSK"
     gene            complement(52295..53353)
                     /locus_tag="ACL29Z_000200"
     CDS             complement(52295..53353)
                     /locus_tag="ACL29Z_000200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000038644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HGR0068575.1"
                     /translation="MSKKLQQISVPLISVFLGILLGAIVMWIFGYDAIWGYEELFYTA
                     FGSLRGIGEIFRAMGPLVLIGLGFAVASRAGFFNVGLPGQALAGWILSGWFALSHPDM
                     PRPLMILATIVIALIAGGIVGAIPGILRAYLGTSEVIVTIMMNYIVLYVGNAFIHAFP
                     KDFMQSTDSTIRVGANATYQTPWLAELTGNSRMNIGIFFAIIAVAVIWFMLKKTTLGF
                     EIRAVGLNPHASEYAGISAKRTIILSMIISGALAGLGGAVEGLGTFQNVYVQGSSLAI
                     GFNGMAVSLLAANSPIGILFAAFLFGVLQVGAPGMNAAQVPSELVSIVTASIIFFVSV
                     HYLIERFVKPKKQVKGGK"
     gene            complement(53346..54881)
                     /locus_tag="ACL29Z_000201"
     CDS             complement(53346..54881)
                     /locus_tag="ACL29Z_000201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000929819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGR0068576.1"
                     /translation="MAHENVIEMRDITKVFGGFVANDKINLHLRKGEIHALLGENGAG
                     KSTLMNMLAGLLEPTSGEIAVNGQVVNLDSPSKAASLGIGMVHQHFMLVEAFTVAENI
                     ILGSELTKNGVLDIAGASKEIKALSERYGLAVDPSAKVADISVGAQQRVEILKTLYRG
                     ADILIFDEPTAVLTPSEIDELMAIMKNLVKEGKSIILITHKLDEIRAVSDRVTVIRRG
                     KSIETVEIAGATNADLAEMMVGRSVSFKTEKQASKPKEVVLSIKDLVVNENRGVPAVK
                     NLSLDVRAGEIVGIAGIDGNGQSELIQAITGLRKVESGSIELKGDSIVGLHPRQITEL
                     SVGHVPEDRHRDGLILEMMISENIALQTYYKEPHSKNGILNYSNITSYAKKLMEEFDV
                     RAASELVPAAALSGGNQQKAIIAREINRDPDLLIVSQPTRGLDVGAIEYIHKRLIEER
                     DNGKAVLVVSFELDEILNVSDRIAVIHDGKIQGIVSPETTNKQELGVLMAGGNLGKEK
                     SDV"
     gene            complement(55025..56077)
                     /locus_tag="ACL29Z_000202"
     CDS             complement(55025..56077)
                     /locus_tag="ACL29Z_000202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001036143.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BMP family protein"
                     /protein_id="HGR0068577.1"
                     /translation="MNKKQWLGLGLVAVAAVGLAACGNRSSRNAASSSDVKTKAAIVT
                     DTGGVDDKSFNQSAWEGLQDWGKEHNLSKDNGFTYFQSTSEADYANNLQQAAGSYNLI
                     FGVGFALHNAVEEAAKEHTDLNYVLIDDVIKDQKNVASVTFADNESGYLAGVAAAKTT
                     KTKQVGFVGGIESEVISRFEAGFKAGVASVDPSIKVQVDYAGSFGDAAKGKTIAAAQY
                     AAGADIVYQVAGGTGAGVFAEAKSLNESRPENEKVWVIGVDRDQEAEGKYTSKDGKES
                     NFVLVSTLKQVGTTVKDISNKAEKGEFPGGQVIVYSLKDKGVDLAVTNLSEEGKKAVE
                     DAKAKILDGSVKVPEK"
     gene            complement(56167..56556)
                     /locus_tag="ACL29Z_000203"
     CDS             complement(56167..56556)
                     /locus_tag="ACL29Z_000203"
                     /EC_number="3.5.4.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004126 - cytidine deaminase activity
                     [Evidence IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_process: GO:0009972 - cytidine deamination [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cytidine deaminase"
                     /protein_id="HGR0068578.1"
                     /translation="MATTELIELAIETSKHAYVPYSHFPIGAVLVAKDGSVYTGVNIE
                     NASYPLTNCGERTAVFKAISEGQREFSELIVYGQTEKPISPCGACRQVMVEFFEQDLK
                     VTLVAKDKSTVEMTVGELLPYSFTDLN"
     gene            complement(56543..57205)
                     /gene="deoC"
                     /locus_tag="ACL29Z_000204"
     CDS             complement(56543..57205)
                     /gene="deoC"
                     /locus_tag="ACL29Z_000204"
                     /EC_number="4.1.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000773666.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004139 - deoxyribose-phosphate aldolase
                     activity [Evidence IEA];
                     GO_process: GO:0009264 - deoxyribonucleotide catabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="deoxyribose-phosphate aldolase"
                     /protein_id="HGR0068579.1"
                     /translation="MKLNKYIDHTLLKQDAKKKQIDSLLSEAREYDFASVCVNPTWVE
                     HAKKGLEGTDVKVCTVVGFPLGATTSAVKAFETKEAIQNGADEIDMVINVGALKSGNL
                     ALVESDIRAVVEASGDKLVKVIIEACLLTDQEKIVVCQLAQKAGADFVKTSTGFSTGG
                     ATIADVTLMRETVGSDMGVKAAGGARSYADALAFVEAGATRIGTSAGVAILKGELADG
                     DY"
     gene            complement(57223..58500)
                     /locus_tag="ACL29Z_000205"
     CDS             complement(57223..58500)
                     /locus_tag="ACL29Z_000205"
                     /EC_number="2.4.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001202959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016154 - pyrimidine-nucleoside
                     phosphorylase activity [Evidence IEA];
                     GO_process: GO:0006213 - pyrimidine nucleoside metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyrimidine-nucleoside phosphorylase"
                     /protein_id="HGR0068580.1"
                     /translation="MRAVDLIQKKRDGQELTSSEIEWLVEGYVSGTVPDYQMSAFAMA
                     VYFKGMTTREISDLTMNMVKTGQEFDLSAIDGVKVDKHSTGGVGDKVTLILAPLVASF
                     GVPVAKMSGRGLGHTGGTIDKLESIKGYQVERSQEDFIRQVQDIGVSVIGQSDQLVKA
                     DKLLYALRDVTATVDTIPLIASSVMSKKIAAGADAILLDVTVGEGAFMKTVDEARELA
                     QTMVDLGKVVGRKTVAVITDMSQPLGRAIGNRLEILEALEILQGQGRQDITHFICELA
                     QIMLGLANVNKTVEEVRQHLENGQALAKFEEMVQAQGGDLEDLYRPVNVAHVVEIPAQ
                     ETGVISALPAMDFGLYAMRLGAGRAVKSDALDYETGIVFEKKMGDSVQKGEIVAKVYT
                     NEKIPPQLVTDFQKCVKISDEVKKIREIVEIIS"
     gene            complement(58497..59087)
                     /locus_tag="ACL29Z_000206"
     CDS             complement(58497..59087)
                     /locus_tag="ACL29Z_000206"
                     /EC_number="2.1.1.172"
                     /EC_number="2.1.1.174"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013670199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0052916 - 23S rRNA
                     (guanine(1835)-N(2))-methyltransferase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HGR0068581.1"
                     /translation="MSKMYYAENPDAAHDIHELRVELLGQKMTFLTDAGVFSKKIVDF
                     GSQLLLKCLEVNQGETVLDVGCGYGPLGLSLAKAYGVQATMVDINTRALDLARRNAEK
                     NNAKATIFQSNIYEQVEGHFDHVISNPPIRAGKQVVHEIIEKSKDFLETGGDLTIVIQ
                     KKQGAPSAKSKMEDVFGNCEILKKDKGYYILRSVKE"
     gene            complement(59294..59697)
                     /locus_tag="ACL29Z_000207"
                     /pseudo
     CDS             complement(59294..59697)
                     /locus_tag="ACL29Z_000207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000698118.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            59887..60807
                     /gene="coaA"
                     /locus_tag="ACL29Z_000208"
     CDS             59887..60807
                     /gene="coaA"
                     /locus_tag="ACL29Z_000208"
                     /EC_number="2.7.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004261526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004594 - pantothenate kinase activity
                     [Evidence IEA];
                     GO_process: GO:0015937 - coenzyme A biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type I pantothenate kinase"
                     /protein_id="HGR0068582.1"
                     /translation="MTNEFLHFEKISRQTWQSLHRKTTPPLTEEELESIKSFNDQISL
                     QDVTDIYLPLAHLIQIYKRTKEDLAFSKGIFLQRESKSQPFIIGVSGSVAVGKSTTSR
                     LLQILLSRTFTDATVELVTTDGFLYPNQTLIEQGILNRKGFPESYDMEALLNFLDRIK
                     NGQDVDIPVYSHEVYDIVPEEKQSVKAADFVIVEGINVFQNPQNDRLYITDFFDFSIY
                     VDAGVDDIESWYLDRFLKMLSLAQNDPDSYYYRFTQMPIGEVEAFAHQVWTSINLTNL
                     QNYIEPTRNRAEVILHKSKNHEIDEIYLKK"
     gene            60875..61111
                     /gene="rpsT"
                     /locus_tag="ACL29Z_000209"
     CDS             60875..61111
                     /gene="rpsT"
                     /locus_tag="ACL29Z_000209"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001274003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S20"
                     /protein_id="HGR0068583.1"
                     /translation="MANIKSAIKRAELNVKQNEKNSAQKSAMRTAIKAFEANPSEELF
                     RAASSAIDKAETKGLIHKNKASRDKARLSAKLAK"
     gene            61164..61688
                     /locus_tag="ACL29Z_000210"
     CDS             61164..61688
                     /locus_tag="ACL29Z_000210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000684222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topology modulation protein"
                     /protein_id="HGR0068584.1"
                     /translation="MKITIIGYSGSGKSTLAEKLSNYYSIPKLHMDTLQFQPGWQDSD
                     CEWMLTEIKNFLTKHKAWVIDGNYSWCYYQERMQEADQIIFLNFLPLTCLFRAFKRYL
                     KYRGKVRESMAADCPERFEWEFIRWILWDGRSKTQKENYQKLCQEYSHKVTILRNQRE
                     LDQFLDKKRKSYNS"
     gene            complement(61711..62421)
                     /gene="deoD"
                     /locus_tag="ACL29Z_000211"
     CDS             complement(61711..62421)
                     /gene="deoD"
                     /locus_tag="ACL29Z_000211"
                     /EC_number="2.4.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004731 - purine-nucleoside phosphorylase
                     activity [Evidence IEA];
                     GO_process: GO:0006139 - nucleobase-containing compound
                     metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="purine-nucleoside phosphorylase"
                     /protein_id="HGR0068585.1"
                     /translation="MSIHIAAQQGEIADKILLPGDPLRAKFIAENFLGDAVCFNEVRN
                     MFGYTGTYKGHRVSVMGTGMGMPSISIYARELIVDYGVKKLIRVGTAGSLNEEVHVRE
                     LVLAQAAATNSNIVRNDWPQYDFPQIASFDLLDKAYHIAKELGMTTHVGNVLSSDVFY
                     SNYFEKNIELGKWGVKAVEMEAAALYYLAAQYHVDALAIMTISDSLVNPDEDTTAEER
                     QNTFTDMMKVGLETLIAE"
     gene            complement(63079..63591)
                     /locus_tag="ACL29Z_000212"
     CDS             complement(63079..63591)
                     /locus_tag="ACL29Z_000212"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001275913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiol-activated cytolysin C-terminal
                     domain-containing protein"
                     /protein_id="HGR0068586.1"
                     /translation="MSAQITINHKKVRYVRIELEGYNALSLAEVEVFRFIATNAETAT
                     QVSKPVQPISQTPVKDKTLTIQHSGAYIARYSITWEEVPVDKDGNQVVRSHSWEGNGC
                     NQTAGFVLNLPIKENMRNLRVKIEKKTGLLWNRWQTIYENRPILAQPHRKITHWGTTL
                     NSKVSDDDVL"
     gene            complement(63616..64191)
                     /locus_tag="ACL29Z_000213"
     CDS             complement(63616..64191)
                     /locus_tag="ACL29Z_000213"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000445853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="discoidin domain-containing protein"
                     /protein_id="HGR0068587.1"
                     /translation="MESRKLAVSGKIKHYVVDNDNVVTPLIHNNRDIVTFTGNSRFKH
                     RSRGYFESPMNDIPNFNIGKQATLDKHGYRDPKLDKARFFKKQALPQSSSQPSAEPME
                     NIALGKQVTQSSTAFGGDARRAVDGKVDGNYGHNSVTHTNFQSKPWWQVDLAKEETIR
                     QINIYNRTDTAQDRLANFDVILLDSSGKEIE"
     gene            complement(64201..64596)
                     /locus_tag="ACL29Z_000214"
     CDS             complement(64201..64596)
                     /locus_tag="ACL29Z_000214"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000887334.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipase family protein"
                     /protein_id="HGR0068588.1"
                     /translation="MLDSKEELKESENDAPKLETPLREEPRLAPQTLPEASEVLENKR
                     EESKVEITEPAQADDIRKVVGELAKDISITKLYMTGHSLGGYLAQIAAVEDYQKYPDF
                     YNHVLRKVTTFSAPKVITSRTVWDAKNGF"
     gene            complement(65072..65881)
                     /locus_tag="ACL29Z_000215"
     CDS             complement(65072..65881)
                     /locus_tag="ACL29Z_000215"
                     /EC_number="2.4.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004731 - purine-nucleoside phosphorylase
                     activity [Evidence IEA];
                     GO_process: GO:0009116 - nucleoside metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="purine-nucleoside phosphorylase"
                     /protein_id="HGR0068589.1"
                     /translation="MTFLNKIHETATFLKEKGIAAPEFGLILGSGLGELAEEIENPVV
                     VDYAEIPNWGRSTVVGHAGKLVYGELAGRKVLALQGRFHFYEGNPLEVVTFPVRVMKV
                     LGCEGVIVTNAAGGIRFGPGTLMAISDHINMTGQNPLMGENLDDFGPRFPDMSRAYTP
                     EYRATAHEVAKKLNIKIDEGVYIGVTGPTYETPAEIRSYKTLGADAVGMSTVPEVIVA
                     AHSGLKVLGISCITNFAAGFQEELNHEEVVEVTERVKGDFKGLLKAILAEL"
     gene            complement(65897..66439)
                     /locus_tag="ACL29Z_000216"
     CDS             complement(65897..66439)
                     /locus_tag="ACL29Z_000216"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1697 domain-containing protein"
                     /protein_id="HGR0068590.1"
                     /translation="MTRYALLVRGINVGSKNKVVMAELHQELTNLGLEKVESYINSGN
                     IFFASIDSKAQLVEKLETFFAVHYPFIQSFSLLSLEDFEAELENLPAWWSRDLARKDF
                     LFYTEGLDVDQVIATVESLELKDEVLYFGKLGIFWGKFSEESYSKTAYQKYLLKVPFY
                     RHITIRNAKTFDKIGQMLKK"
     gene            complement(66441..67652)
                     /locus_tag="ACL29Z_000217"
     CDS             complement(66441..67652)
                     /locus_tag="ACL29Z_000217"
                     /EC_number="5.4.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019318858.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000287 - magnesium ion binding [Evidence
                     IEA];
                     GO_function: GO:0008973 - phosphopentomutase activity
                     [Evidence IEA];
                     GO_process: GO:0009117 - nucleotide metabolic process
                     [Evidence IEA];
                     GO_process: GO:0043094 - cellular metabolic compound
                     salvage [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopentomutase"
                     /protein_id="HGR0068591.1"
                     /translation="MSKFNRIHLVVLDSVGIGAAPDANNFVNAGVPDGASDTLGHISK
                     TVGLNVPNMAKIGLGNIPRETPLKTVAAESNPTGYATKLEEVSLGKDTMTGHWEIMGL
                     NITEPFDTFWNGFPEEILTKIEEFSGRKVIREANKPYSGTAVIDDFGPRQMETGELII
                     YTSADPVLQIAAHEDIIPLDELYRICEYARSITLERPALLGRIIARPYVGEPGNFTRT
                     ANRRDLAVSPFSPTVLDKLNEADIDTYAVGKINDIFNGAGINHDMGHNKSNSHGIDTL
                     LKTMGLAEFEKGFSFTNLVDFDALYGHRRNAHGYRDCLHEFDERLPEIIAAMRENDLL
                     LITADHGNDPTYAGTDHTREYIPLLAYSPAFKGNGLIPVGHFADISATVADNFGVETA
                     MIGESFLDKLV"
     gene            complement(67666..68349)
                     /gene="rpiA"
                     /locus_tag="ACL29Z_000218"
     CDS             complement(67666..68349)
                     /gene="rpiA"
                     /locus_tag="ACL29Z_000218"
                     /EC_number="5.3.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000429260.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004751 - ribose-5-phosphate isomerase
                     activity [Evidence IEA];
                     GO_process: GO:0009052 - pentose-phosphate shunt,
                     non-oxidative branch [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-5-phosphate isomerase RpiA"
                     /protein_id="HGR0068592.1"
                     /translation="MENLKKMAGIKAAEFVSDGMVVGLGTGSTAYYFVEEIGRRIKEE
                     GLQITAVTTSSVTTKQAEGLNIPLKSIDQVDFVDVTVDGADEVDSQFNGIKGGGGALL
                     MEKVVATPSKEYIWVVDESKLVEKLGAFKLPVEVVQYGAEQVFRHFERAGYKPSFREK
                     DGQRFVTDMQNFIIDLALDVIENPIAFGQELDHVVGVVEHGLFNQMVDKVIVAGRDGV
                     QISTSKKGK"
     gene            complement(68631..69503)
                     /locus_tag="ACL29Z_000219"
     CDS             complement(68631..69503)
                     /locus_tag="ACL29Z_000219"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000864675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016836 - hydro-lyase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-hydrate dehydratase"
                     /protein_id="HGR0068593.1"
                     /translation="MKVINQILLEKVIIERSRSSHKGDYGRLLLLGGTYPYGGAIIMA
                     ALAAVKSGAGLVTVGTDRENIPALHSHLPEPMAFSLQDQQLLKEQLEKAEVVLLGPGL
                     RDDASGENLVKQVFVNLSQNQILIVDGGALTILARTSLSFPSSQLILTPHQKEWEKLS
                     GITIEKQKEDATASVLTSFPQGTILVEKGPATRIWEVGQSDYYQLQVGGPYQATGGMG
                     DALAGMIAGFVGQFRQASLYERVAVATHLHSAIAQELSQENYVVLPTEISRYLPKIMK
                     IICQQERVSKDKLV"
     gene            complement(69645..70502)
                     /locus_tag="ACL29Z_000220"
     CDS             complement(69645..70502)
                     /locus_tag="ACL29Z_000220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000192112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004488 - methylenetetrahydrofolate
                     dehydrogenase (NADP+) activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional methylenetetrahydrofolate
                     dehydrogenase/methenyltetrahydrofolate cyclohydrolase"
                     /protein_id="HGR0068594.1"
                     /translation="MTQIIDGKALAAKLQGQLAEKTAKLKEETALVPGLVVILVGDNP
                     ASQVYVRNKERSALAAGSRSEVVRVPETITQEELLDLIAKYNQDPAWHGILVQLPLPK
                     HIDEEAVLLAIDPEKDVDGFHPLNMGRLWSGHPVMIPSTPAGIMEMFHEYGIDLEGKN
                     AVVIGRSNIVGKPMAQLLLAKNATVTLAHSRTHNLAKVAAKADILVVAIGRAKFVTAD
                     FVKPGAVVIDVGMNRDENGKLCGDVDYEAVAPLASHITPVPGGVGPMTITMLMEQTYQ
                     AALRTLDRK"
     gene            complement(70656..71390)
                     /locus_tag="ACL29Z_000221"
     CDS             complement(70656..71390)
                     /locus_tag="ACL29Z_000221"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000140960.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HGR0068595.1"
                     /translation="MTETLIKIENLHKSFGKNEVLKGINLEIKRGEVVVIIGPSGSGK
                     STLLRSMNLLEEATKGKVIFEGVDITDKKNDLFAMREKMGMVFQQFNLFPNMTVMENI
                     TLSPIKTKGESREVAEKRAQELLEKVGLPDKADAYPQSLSGGQQQRIAIARGLAMEPD
                     VLLFDEPTSALDPEMVGEVLAVMQDLAKSGMTMVIVTHEMGFAREVADRVIFMADGVV
                     VEDGTPEQIFEQTQEQRTKDFLSKVL"
     gene            complement(71390..72073)
                     /locus_tag="ACL29Z_000222"
     CDS             complement(71390..72073)
                     /locus_tag="ACL29Z_000222"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001011621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0006865 - amino acid transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HGR0068596.1"
                     /translation="MNFSFLPKYLPYFNYGAVVTILISICVIFLGTILGVVLAFGQRS
                     KFKPLVWLANLYVWIFRGTPMMVQIMIAFALMHINAPTIQIGILGVDFSRLIPGILII
                     SMNSGAYVSEIVRAGINAVPKGQLEAAYSLGIRPKNAMRYVILPQAVKNILPALGNEF
                     ITIIKDSSLLSAIGVMELWNGATTVSTTTYLPLTPLLFAAFYYLIMTSILTVALKAFE
                     KHMGQGDKK"
     gene            72263..72493
                     /locus_tag="ACL29Z_000223"
     CDS             72263..72493
                     /locus_tag="ACL29Z_000223"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005592360.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1797 family protein"
                     /protein_id="HGR0068597.1"
                     /translation="MESHLVRIINRLEAMANDGGNLKRNFEREGVVVAEVAYSHDEEN
                     GPIFTLRDVEDRETYTFDSIDLIAMEIYELLY"
     gene            72722..74980
                     /locus_tag="ACL29Z_000224"
     CDS             72722..74980
                     /locus_tag="ACL29Z_000224"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HGR0068598.1"
                     /translation="MLCQNCKINDSTIHLYTNLNGKQKQIDLCQNCYKIIKTDPNNSL
                     FKGMTDLNNRDFDPFGDFFNDLNNFRPSSNTPPIPPTQSGGGYGGNGGYGSQNRGSAQ
                     TPPPSQEKGLLEEFGINVTEIARRGDIDPVIGRDDEIIRVIEILNRRTKNNPVLIGEP
                     GVGKTAVVEGLAQKIVDGDVPHKLQGKQVIRLDVVSLVQGTGIRGQFEERMQKLMEEI
                     RKREDIILFIDEIHEIVGAGSASDGNMDAGNILKPALARGELQLVGATTLNEYRIIEK
                     DAALERRMQPVKVDEPTVDETITILKGIQKKYEDYHHVQYTDAAIEAAATLSNRYIQD
                     RFLPDKAIDLLDEAGSKMNLTLNFVDPKVIDQRLIEAENLKSQATREEDFEKAAYFRD
                     QIAKYKEMQKKKITDQDTPIISEKTIEHIIEQKTNIPVGDLKEKEQSQLIHLAEDLKS
                     HVIGQDDAVDKIAKAIRRNRVGLGTPNRPIGSFLFVGPTGVGKTELSKQLAIELFGSA
                     DSMIRFDMSEYMEKHSVAKLVGAPPGYVGYDEAGQLTEKVRHNPYSLILLDEVEKAHP
                     DVMHMFLQVLDDGRLTDGQGRTVSFKDAIIIMTSNAGTGKTEASVGFGAAREGRTNSV
                     LGELGNFFSPEFMNRFDGIIEFKALSKDNLLQIVELMLADVNKRLSSNNIRLDVTDKV
                     KEKLVDLGYDPKMGARPLRRTIQDYIEDTITDYYLENPSEKDLKAVMTSKGNIQIKSA
                     KKAEVKSSEKEK"
     gene            complement(75187..>75482)
                     /locus_tag="ACL29Z_000225"
     CDS             complement(75187..>75482)
                     /locus_tag="ACL29Z_000225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HGR0068599.1"
                     /translation="EEMMTSDFFEAWFQKFLLPTLTTPSVIIMDNARFHRMGKLELLC
                     EEFGHKLLPLPPYSPEYNPIEKTWAHIKKHLKKVLPSCCNTFYEALLSCSCFN"
BASE COUNT        22580 a        16653 c        13442 g        22807 t
ORIGIN      
        1 tctcctagaa cttttatacc ctatctattt attcttattg ttactctgtt ctctatattg
       61 aatttagtac tttattcatt tttattggat tatttccttt tgaagttaac aattcccttt
      121 ctgctttttt tttgatataa taaccttaac tgtcattcta tatggaggtt ctatgcgttt
      181 taatcaatat agttatatca attttccaaa agaaaatgtc ttatctgaac taaaaaaatg
      241 tggctttgat ttacaaaata cagccaatca caaagactca cttgaaacct ttttacgtcg
      301 tttctttttc acttatcaag acaccaacta cccactttct atcctagcag ctgataaaaa
      361 aacagacctg ctgacatttt ttcaatcaga agatgaactg acagcagata ttttttatac
      421 tgttgctttt caacttttag gcttttctta tttggttgac ttcgaagata gtgacgtttt
      481 tcgtaaagaa actggatttc ccattatata tggtgacttg attgaaaatc tctatcagtt
      541 actcaatact cgcaccaaaa aaggaaatac tcttatcgac caacttgtta gtgatggtct
      601 tattccggag gataatgact accactactt taacggcaag agtttggcta ctttttctaa
      661 ccaggatgtc attcgtgaag tcgtttacgt tgagtctcgt gtcgatactg accaaaaagg
      721 gctatcagac ctagtaaagg ttagcattat tcgccctcgt tttgatggaa aaatccctgc
      781 catcatgaca gccagccctt atcatcaggg aaccaatgac aaggctagtg acaaggctct
      841 ctacaagatg gagggcgagc ttgaggttaa gcttcctcac aagattgagc tagagaaacc
      901 tcaactaaat ctcgtccaac cccaaggtaa agctgagctt atagcagagg ctgaggaaaa
      961 gctaactcac atcaactcta gctatacact aaacgactac ttccttccga gaggctttgc
     1021 caatctctat gtctcaggtg ttggtaccaa agactcgaca ggtttcatga ctaatggaga
     1081 ctaccagcaa atcgaggctt ataaaaatgt catcgattgg cttaacggcc gttgccgtgc
     1141 ctttactgat cacacgcgcc agtgtcaagt caaggctgat tggtcaaacg gaaaagttgc
     1201 tacaacagga ctttcctatc taggtaccat gtccaatggt cttgcgacta caggagtcga
     1261 tggtttagaa gttatcattg ccgaggcagg aatttcatca tggtacaact actaccgtga
     1321 aaacggtctg gtgactagcc caggtggtta tccaggtgag gactttgact cccttgctga
     1381 gttaacctat tctcgtaatc tcttagctgg cgactatatc cgtggcaatg aagctcacca
     1441 agctgactta gaaaaagtga aagctcagct agaccgaaaa actggggact acaatcagtt
     1501 ttggcatgac cgcaattatc tgctcaatgc ccataaagta aaggcagagg ttgtctttac
     1561 tcatggttct caggattgga atgtcaaacc acttcatgtt taccagatgt tccatgctct
     1621 tcctactcat atacacaagc atctcttttt ccataatggt gctcatgttt acatgaacaa
     1681 ttggcaatca attgacttcc gtgagtccat aaatgcctta ttgaccaaga aattactagg
     1741 acaggaaaca gactttcaac ttcctactgt tatctggcag gacaatacag ctccacagac
     1801 ttggttatca cttgataact tcggtgggca agaaaactgt gaaaccttct cacttggtca
     1861 agaagagcaa gctattcaaa accagtaccc agataaggat tttgagcgct atggtaagac
     1921 ataccaaacc ttcaatacag agctctatca agggaaagcc aatcagatta ctattaacct
     1981 tcctgtgact aaagatctcc acctaaacgg tcgcgctcag ctcaatcttc gtatcaaatc
     2041 cagtacaaac aaggggctct tatctgccca actgctagaa tttgggcaaa agaaatacct
     2101 acaaccttat ccagccattt taagtgctag aaccattgat aacggtcgct atcacatgtt
     2161 ggaaaatctc tgtgaattgc catttagacc agaggcacaa cgagtcgtga caaaaggtta
     2221 ccttaattta caaaatagaa atgatttact gttagtagag gatattactg cagatgaatg
     2281 gatggacgtt caatttgaac tgcagccaac tatttacaag ctaaaagaag gagacactct
     2341 ccgtttagtc ctctatacta ctgactttga aatcaccatc cgtgacaata cagactacca
     2401 cttgactgtc gacctcgctc agtccatgct taccttacct tgctaaaagg agttacatta
     2461 ttatgaataa atcagaacac cgccaccaac ttatacgcgc tcttatcaca aaaaacaaga
     2521 ttcatacaca ggctgagttg caagcccttc ttgctgagaa cgacattcaa gtaacccagg
     2581 caaccctctc acgcgacatc aaaaatatga acctatcaaa agtccgcgaa gaagatagcg
     2641 cttattatgt tcttaacaat ggttccatct caaaatggga aaaacgtctc gaactctaca
     2701 tggaagacgc ccttgtctgg atgcgcccag ttcaacacca agtcctacta aaaacccttc
     2761 ctggactggc tcaatccttt ggttctatca ttgatacttt gagcttccct gacgctatcg
     2821 ctaccctttg tggtaatgat gtctgtctta tcatctgtga agatgcagat actgctcaaa
     2881 agtgctttga agaactgaaa aaattcgccc caccattttt ctttgaagaa taataaatga
     2941 ctacaactaa caattatgct taaaaaaaaa ctggtagaaa gtctttaaca tcagaaaacg
     3001 catagtatca agtgttgaaa acccttgata ctatgcgttt tgctttatcc taggaagatt
     3061 tatactcttc gaaaatctct tcaatccgcg tcaacgtcgc cttgccgtag gtatggttac
     3121 tgacttcgtc agtttcatct acaacctcaa aacagtgttt tgagcagcct gcagctagtt
     3181 tcctagtttg ctctttgatt ttcattgagt attatttcat tttctcctgc aattgaattc
     3241 ttgctcagct ttttgttttc tatttcttta aaatcaaagt agctcttttg ttaataactc
     3301 gatcaacaaa catcgtggta caagtatcta ctttgaaatt tatcaaccac ttaacaactg
     3361 atactgtatt ctaggaaaac gatgacattc ttcctaataa aacttctcat atatagcata
     3421 aatttctact ctttttaatt ttaaatgagt ctcagcatgg caatcacttt agaatttaag
     3481 ccgcttctcc agctcgatta ttgataagtt caatgatttg aacaatacta cgaagtactg
     3541 gtagttggtg ttggaagagt agttgaacag atccataaga tttaaacggc tcttgcgtta
     3601 acactttcgt ctctaaaaaa ccattttcta caatgtagtc tacaatcaat tttacaaatg
     3661 aaatctgcct ggcattaaga ttctcatccg acaaaaattt agaaaaaata cgattggcag
     3721 actctctatc taagccaata atctcacgaa ccaatctcgg aattgcctta ttttcataat
     3781 gactttggta gtctgcttta ctacctaatt tttcccaaag caatttttca agtgcaagca
     3841 tatcatcaga tgtcaacttt ttattatggt atagcttaga aatggactcc tcatccagat
     3901 gagttttcaa ataatgctca actttttcat tgtaagaccg aagatcgttg acctgcaaaa
     3961 atgctgtggt ctcgtgaaca gtggagagta tacgatcttc aaagttaaca tagtagggtt
     4021 tacggtctgt tttatccaaa aactgtaata aatctcgaat agcaagacga attttttcca
     4081 aatcagacaa gttaacttct ttccaaaatt caggctcctg tactttcctg ataatttcag
     4141 cctgctcaaa aacctgcggg atattgccaa tagcagaaag agctctagcc gtcttcatca
     4201 cttgggaaat atgaacagtg gaagatttag ctgtcagttg ccccaactga atatgaagca
     4261 accacaaatc aaatctcctc gccatctcat cttctttatc ttcatcaaat aaaagcggag
     4321 agagattttt ttgaatggtt tcacttgtaa cagcagttag attctgccaa ctttccaatt
     4381 tcctatagct ataaactgta tctaaaacca tacgaaccct gaagtccaac tcatttaagc
     4441 tctctatacg accttgaagt tccgagacaa gctgctgacg gtatgctctc gcaaactgat
     4501 cttcttggta ttggagtccc tgaagttctc gaatcaagtc cactttgata ttaaataaac
     4561 gctgagtcag cgaaacaatg tgacgaccct ctccatctct tggatctgca cgaaaataat
     4621 caaaattgtc cccataatca aataccaaga agttttcctt atcctgctca ggtccaaata
     4681 aatctttaca tagacgggtt cctcgaccaa tcatctgcca aaacttagtt ttagagcgta
     4741 ctttcttgaa gaagactaaa ttaacaacct ctggtacatc aatacctgta tctaacatat
     4801 cgacagaaat cgcaatttga ggatacttct ccttaatttt aaaatcatca atcaaggtct
     4861 gataatgctt aatactataa tcaatcacct gagcatagtc gctccctttt tcaggatagc
     4921 ggttgttaaa aatacctctg atatattccg catgatcatg atttttagca aaaataatag
     4981 ttttaccaat ttcatcaccc gaggctgtct gaattcctct tgtcatgagt tcatttaaaa
     5041 caatttctac tgtactttta ttgaaaataa aggaattaaa tacactccca tcaatatctt
     5101 tttcacagct atcgtcttca aatttgctat caaaatgttc cttttcttct tcggacaaat
     5161 catcataatg tagaccatcc gtaggtagtt tcagtttggt ttcgatagaa tgataggcta
     5221 ctaaatatcc gtctttaaca gcctcttcca aatcatatgc atatgttgga accccattct
     5281 ccaaattaaa gaatccatag gtgtttttat ctaaatcttg acgcggagta gctgttaagc
     5341 ctacaattct tgcatcaaaa taatcaaaaa tggacttgta tttctgataa atagaacggt
     5401 gagattcgtc aattatgata aggtcaaaat gcccaacagt gaaagggcgt tgatttactt
     5461 cttcttgacc actaatcgct ccaatcatgg tcggataagt tgaaaagacc atgcgacttg
     5521 attgagctcc ttctttatct tctaagaagt tacaaacgga aagatctggg agtaattttc
     5581 taaacgaatc ataggcttgc ttaaccaagg aagttctatc ggctaagaag agaacgtttt
     5641 ttacccagtt atgacgtgat aagatatcaa ctagagaaac tgctgtacga gttttcccag
     5701 ccccagttgc cataaccaaa agtgcctgtc tacgatgatt agagaaagct tcacaaacgc
     5761 ttgcaatggc gtgtttttgg tagtgacgcc cggaaatatc gtccctaatt ttactagaaa
     5821 tatcctcaag tggtttttga agatgacgtc tatccatcac taattgcaat tcttcttgag
     5881 agtaaaagcc tgcaatctgg cggcggttcg gaccatcaag tatatagtgc ttcaagccat
     5941 ttgtaataaa gcaaattggc tgatagccga tatgtttctc aagagcttca gcatattctt
     6001 tgacctgtac ttcccctact tctggattga cagaggcttt tttagcctct acaatcgcta
     6061 aaattttccc atttttacca taaagtacat agtcacagta accaattcct gaaccgtgct
     6121 tgagaccatc aacggctatc tcaacacgac agttttcttc aaatatccat cctgctaaac
     6181 ggagatcgat atcaataaag agctttcttg tctctgcctc agataattga tcaatatgga
     6241 aaggcacatc ttgccgttgc gctgcagtct cacgtttttc agtataagtc tcttgaactt
     6301 ctacggactg agcagccatc tgttcatgaa aatcaggcag ttctggtaaa ctgtcttgta
     6361 actttatcat agattgtgga gtttctcggt atttgatgtt tgctgaaagt ggtaagcact
     6421 tctcatcaaa ataacgctcc acaaactcat tgctgtaaca ataatcgata aaattaacaa
     6481 actgatacaa atgatgcaaa gctaaaatcg cttctcgttc cttaatttca ccaccatgag
     6541 cagcatggtt tccccaccga atcaacagaa ctatctgctt gtggagttca gaatctacga
     6601 tatccctaaa atcatcatcc catactaaag aagatagagt agcacgatag ggagcttcta
     6661 aatatgaatc gtgactatat atccaatgga cagcctgctc taaagcacga cgcgccataa
     6721 aggcagtagc cacagttgat gtagcaatca tattctcagc ttcaatgcaa ggttttgaaa
     6781 aagattcata ttcgtcattt tttaaaagaa agctaaaatt tcccattttt ttctcacttt
     6841 aaacaaatag tttagctata ttatactaaa tttcaagcta tttctccaca cttttatagc
     6901 tatctcacaa gcaaattgtg atttgtcgac ctgaactaca aagtctgcga actcattttg
     6961 gagggctaga ggggggagga tatatttctg attttctaat ggtttttgag ttatctttgg
     7021 ttgacctgag aaatcagcaa atttactaaa atcaattact ttcattaatt ctaataaaaa
     7081 tacaagattg aaatcggaat tcttaaattc ttttatatat atagcattgt cacttatcca
     7141 taccttaccg tgggtagttc ttacattacc acaatatgca cctacacgac caatgatgat
     7201 agtaggatta tcaattaaat attttcgact tttccaagca atgccatttc caccataggc
     7261 aggataacct tcaaaaactc tatcatgttt atcaagaaat tttccacttg aaaatttaaa
     7321 acactgttgt cccgttttta ctgcaaattt cttgttatta tttaaaggat ccccaaacat
     7381 ctcgttaaat cgggatttta caagtagatt aagctcttca agttgttctt gtctccttaa
     7441 aatcagcttg cttaacaaat ccagctcact tgcaattctt tgttgctctc ccaaatttgt
     7501 atatggaact ataatattat caaaatattt tttagttaaa tgtttcattg tggaaccatg
     7561 agtatgtttt acagcatctt gtaaaccttt ttcaacaaca tatttaaaat acgatttatc
     7621 tatatctatc ttatcaaaaa ccactttaaa aatgtgctga tttaacactg cggatcttcc
     7681 acaccactga aaaaccccta atgtacccga ccacgaaata agaatatcac cagcttcaac
     7741 aatgtatttt ttatcaatcg tacccgaata ataatttatc ccttttgaag ttttagtcag
     7801 attctgtatt ctgataatct ctttcccttc agatgaccaa tcttgaggtt taaaagcata
     7861 gccattgata aaagtagcca cttgccctaa tttcactttc ttcatgcaac cacctcctcg
     7921 gaatatcggg atttgctttt aagagatgaa tttttggtgt gaatgcttga cattattttg
     7981 attgaccatg gcataggcca gggttgtgtc aatcttgcta tgacctagca gtttttggac
     8041 ttgttcgata ggcatacctt tatcaattgc cttagtcgct aaagttcttc tgaacttatg
     8101 tgggtgaacc ttttgtatgc cgagtttgtc tcctaacttt cttaagcgaa tctctacacc
     8161 agcaattcca agtctctggg cttttccaac tagcgttaca aaaagagcag ggtgactatc
     8221 ttttctgtcg ttaagataat ttcttaaatg aattttcgtc cgagcatcaa aatatactgg
     8281 tctctccttc tttcctttac caaagacaac acactctctg ttttcaaaat caatatctga
     8341 acgattcaac tgtacaagct cccctacacg catacctgtc gatgctagta agtctattat
     8401 tgccaaatct ctcaaatttt cacagttatc acgcataatt tccaaatgtt catcagtata
     8461 agtttccttc acattttgct cagtcttaat tttctttatc cgttgaatgg gatttttaat
     8521 gatatattcc tcttgctcaa gccaagcaaa aaaagaagac aatatacgcc taatattgtc
     8581 taaatttgcc ttactacaat ccttttcaga ctggtaattt gctaaataac tccttaaatc
     8641 atctgttgtg agttgtgtca cagactcttt aatagcatta aacaagtttt caatcgtcct
     8701 ctggtaataa cgaattgttt ttgagctaca gccctctacc tgcttggcgg taataaatag
     8761 ttgcaacagg ttattattcg aatacttctg ctgctttttt ccgtctacta gatgatgttc
     8821 taaactctct ctcaacgcta gtaattgttc attatttaaa agaggtaaca tttcttgcat
     8881 gataattgta acttttgatt ccataatttc tcactttctt attcatcaat aaaaagagac
     8941 aatatcagtt tctgcattac agaattctaa tattgtctgt tcatttattt tcttgtgctc
     9001 attcaaatcc agcatactag gttacttttt gaccttttct ctaacagaat gttcagaaac
     9061 ccatttggaa tagcttgtca ttttttcatc agttaaagct tctactgcga tggttacaca
     9121 catttttact gcttcttcta ccgttacaga aaaacgatag ccgtttaatt gtaaaaattt
     9181 gaccaaaacg aagaaagcag ttcttttatt agcattagca aaaacatgct tctttatcaa
     9241 ttggacaaat agtatcgttg ctttatcaaa aattgttgga taaagagact tcccaaagac
     9301 aaattgttct ggtaagttca caatcatatt taaggcagaa gaactaactg tttgaatttt
     9361 ctcatttgga gaataccgtt gaattgctaa agcatttatt ttttcaattt gcttttctgt
     9421 cagatagatt gtcatttttc caccaaagct ttgaaaacat cgtcgtattc gtcaaatatt
     9481 ttatctaaat ttaagtcaaa ggcatcatca gatacataag aaacctgctg ccccaattct
     9541 tcaggagtaa agataatctc accactttgt aacaatttcg cttcgtattt aacaccactt
     9601 ggaatattaa attcacttgg aatcgtaatg gtgattgaat ttccttgttt tcttgttttt
     9661 actaccatct gatttcctcc tttgaagtat tataacaaat cattaccgta attacaatgg
     9721 cagaatatca gccaaaatac tcctgcatca gagatttctt caaagtttca agttcttcca
     9781 gagatttttg gattgccaat tgtgatttgt cgacctgaac tacaaagtct gcgaactcat
     9841 tttggagggc tagtgggggg agggggagaa gtattttttt taattttgta attggtaact
     9901 gaggctgagc acttcctgat atcactcgac tataattatt atttcttaaa acatggataa
     9961 taaatttctg atttagattt ggtgtcttgg gacgtaatat taccatacct gaatttatac
    10021 gtaaatgttt atattttatt aattcatcgt agtacgctac atttccaaca gtacctcttg
    10081 ttgtcaagac tatatcataa cgctcaagtt tgccttttcg aagtaattta tcctttgttt
    10141 tagtgataaa ttgctttgta tcgaatgaaa atccgttttt agtaacattc tttgtattta
    10201 aaaataaaca gtactcctca ctaaacaact catctgattt aggataattt ttgcccctat
    10261 caccatctat aatatcaaat aagttatcaa tgctttcaaa tattttattt tccccaaaca
    10321 tctcgttaaa tcgggatttg acgagcaagt ttagttcatc taactgaaat tttcttttag
    10381 taataagcct tttaatcgta ttaagaatac agataatgtt ctcttgttct tcgataccta
    10441 gcaattctaa ttgtaaatca agtaatatat tcttgtttaa atgaggaata gttgcacctg
    10501 ttgaatgttc tcgtaaatac tgcgatttac tttccaaaaa gactcccaag taatctgata
    10561 taattttttc tttgtatcgc tcattctttt ttaagaccgt aattgtacta ccaacagctc
    10621 ccgataaccc atagccaact gttcctgcat tagcaccatc ccatgctatt agaatatcat
    10681 ctgggagtgc ttcagtcata tttaaacttt cagtgaattt taaattatta ttatttctta
    10741 aatcatctat ttgaatataa cgttggctta gagttgtttg ttcagcaagt acagtggctt
    10801 tctttccttt ttttagagat aagatttccc ccaacttcac ttttttcata cagccacctc
    10861 cctacttgag taatttttcc aattcagcca agccagcttg aatttctttt tctaaatcat
    10921 tgattttctt taagatgact tctgttggtt catactcaac tttttcatac tcaatctctt
    10981 tatatttatt gatagacaaa tcataatcat tttcctttat ctcagcaact ggaacaaaga
    11041 aagattgatc cgttctctga cgttctgctt ctttttcaag atgatgaaag cgttcgataa
    11101 tatctggaat atcattgtcg ctaatcggtt gtcgcttatc atccaaactt aaaccatccg
    11161 ctttcatatc gtaaaaccag actttgtcag taccaccatt accagttttt gtaaagatga
    11221 gaatggcagt tgaaactcca gcataaggct tgaacacacc actaggcatt gagattacag
    11281 catcaagctt atgattctct acaatttcct gacgaattcc tttatgagct ttagacgaac
    11341 caaaaaggac accatcaggt acgataactg ctgctcgtcc acctggtttt aaagttcgca
    11401 agaaaagaga aagaaagagt aattctgttt ttttggtttt tacggttgca agaaggtcat
    11461 tagaggttga attgtagtca agtgagccct taaaaggagg atttgctaaa accaaagtat
    11521 atttatcggc ttcttcatta tcttgagaca gcgagtcaag gtaactgatt tgtggatttt
    11581 ctactccatg tagcatcatg ttcatcgccc caagtctcaa catagtcgta tccgtatcat
    11641 ttccatgaaa catctgatta tgaaaatgat tgatattatc tgtattggtt tcccattcat
    11701 ctttcttacg ctttaagtaa cggctagcag atactaagaa gccagcagaa cccatagcgg
    11761 gatctgagat gatatctttg atagtcggtt gcatcaactc aaccatcata tcgatgatgt
    11821 gacgaggtgt acggaactgt ccatttttac ctgcggtcga caattttgat aacagatatt
    11881 catagatatc tccgatatca gtaatacttt gtttgtcatt atcaaaatct acatctaatc
    11941 ccctagttgg aaaaacatct aagatagaaa ttgccttttg aagcgtagca ggtttattta
    12001 tttgaaaaat agcttctcgc atatatcgtg aaaaggctgt atcatctgta tcccccttga
    12061 gatttttaat aaacggaaaa atctcctgag tcattaaacg ataaacttcc tgagcatctc
    12121 ctatattttt aaaagttgac caacggtatt caggtttatc ttttggaaaa actccctcat
    12181 aaggaatccc tagaaattca gcatcacttt cacgtccaag ctcgacacta tccaaatctt
    12241 tcataaataa gagataagtc aactgttcaa tatttgttaa aggatttgcg tttccttctg
    12301 tccaaagaat ttcccacagc tgatcgattt tattttttaa ttcgcctgta atcatatctt
    12361 cccttttctt tagtttttaa aacttagtaa tatcattatt ttatcagatt tcaaacaaag
    12421 cttcaattaa ctatatctat gcgtcacctg aatattttat actcttcgaa aatctcttca
    12481 aaccacgtca gcttcacctt gccgtaggta tatgatactg actctgtcag ttctatccac
    12541 aacctcaaaa cagtgttttg agcaacctgc ggctagcttc ctagtttgct ctttgatttt
    12601 cattgagtat taatagactg gtttggtatc ctgaaaacta tatcgtatag gtgtcgtcat
    12661 ggatcctttt agctgattta aggatacgaa aacacaatac tatgactaaa ttgaaatgtt
    12721 aaaattcaat ttctagccac ctaatcctgc ttcaaatagt tatcgaacaa gttttatgat
    12781 agctaccttg ttaggatgct cttatttttt accagacaaa acaaaaggat taagggagtg
    12841 aatttcctta atccgatagt tcttattctt gacgttgtcc gaaatcagca atcatctgat
    12901 ccatttcttg tcgactcgga gttgtcagca tatacaggta atctccttga agttccgcga
    12961 aggcagctgg catgactttt ttaaccttga actgctggct atatttggca agcaaatcct
    13021 cttctgaata aacatagtga gcatttgcac ggcgagaagt agccaaacaa tactgagttt
    13081 caaagtctga cgccgggaac tcctctcctg cgacaatagc tgcatagcca cgataaaggt
    13141 ccaaggaatg agcaaagtta taaacatcaa tggtaaaacc acctgcaggg cggttattgt
    13201 actcgatggt aatataatcg tccccctcac ggaagaactc aatatggaaa aaccgttctt
    13261 tcataccaaa ttctttgaca attgcttccc catacttgcg cagtttagga tccatatcct
    13321 tgagcacata ataagaattg tccatcttat aaatcatgag gtcaagcggt gtataggcgt
    13381 agtcaaaggt tgttgagaag acaatctttc catccttgtc cacgagcccg tcaaaggtac
    13441 agatttcgct ggaagtgaca aatttttcaa agaaataaag ggttgaatgg tcccattctt
    13501 gcttgaagtg attgatatcg tcttctgtct caagtttaaa ggttgcggct gctcccactc
    13561 cattatcagg tttggcaatc attggaagac cgatttcttt cactgcttga tcaacatctg
    13621 cttccgtctt gataacagct ccaggtacca caggaacacc tgcttttttg aaaagtttct
    13681 tcatttcaga cttatatttc gtctttttga gatcctctgg tttggcacca aaaacattga
    13741 attgttctct gagtgttgcg tctagctcaa gccagtattc attgtgagac tcgatgcggt
    13801 caattggacc atgtttataa aagagaaaag caactgcacg tttgacttca tctatgttct
    13861 caagattatc aacacgaaaa tactcggtca agctattgcg caagggctca tccaattgct
    13921 cgtaagactc ttgaccaatt cccaagactg tgatgccttt attagctagt tcgatggtaa
    13981 actgttgaaa gttttgtgga tagtagggag aaataacaag gtaattcata ggtaactcct
    14041 tttataaata gagattaccg aggaaataag gcatttgttt acgccaccat tcccagtcgt
    14101 gggcgacatc atgtccccat tcagcaaacc aggctggaat ttgtttctgg tcaaaggctt
    14161 ctttgagctt gtaaaaggat ggcaaaccat cttgttccca ggctccaagc cccgtacaca
    14221 gcacaatctc tgcctgacgg taacggtcaa taaaccagcc gtcgttttgg ttccaaatat
    14281 aatctactgg cgagttttgg taaatagcat catcgttgta gtaatcaccg acaaagaaac
    14341 gtgcgtcgta aacaccactg agagcaatca ctttggtaaa gacatctgga tgctggagga
    14401 agaaattgag tgcatgatag gctcccatag agcaacctgt cgtcatcatg ccatcaaacc
    14461 aacctgtctt gtgcttgata aaagaatggc ctcctcaatc acataacatt cgtaggcacg
    14521 gtgcatttcc gcttggtcat gagcattttt ccaagtagcc aaccagctct cactatccaa
    14581 actagatagg gtaaagaact ggacacggcc ttcctcgata aaggaagcac aggcatcaat
    14641 catgccaaaa tcatagtatt cgttgtgact actacctgat gaagcaaaga ccacaactgg
    14701 aatcccacca tgtccataac ggttaaggta catttcacgg ttaggatgac cactccagtg
    14761 gctaagatgt tcaatatgca tttcgttttt tcctttctta acttaccatt tttctgcaaa
    14821 aaatctcaga caatctggta gattttctga ccaagggatt tcactatgga tggcaccaga
    14881 ctgaactttt agcacaagat tatccagatg tactccccct gctatcaaat catggtaata
    14941 gcaaagcgac gagtcgatat aggcttgttt gatattgcca tccatcaagg tcttgtctgt
    15001 atcatctgct tcttctgttc ctacatagat gaagatgcgc tggtcaggcg atagtttctg
    15061 gcactcgata tagcggttaa aggcttcttg gtggagccag tttgcagatg aaaaaacgcc
    15121 caagcaacca atttggtctt ggtattccaa accgataaac tgggtaatat tgcctcctag
    15181 tgaggaacca atcatagccg tatgctggca gtctgctttt gtacgatagg tctcatcgat
    15241 aaaaggcttg accacctcca tgacaaactc agcatactcc acacccttac caccaaactg
    15301 ctgctctggg ataggaaatt cttggaactt ccaagccgca tactcattca ttcgccccat
    15361 accatcattg tcaatagcaa cgacaatcat gcgactgata tactgatatc cggatttcgt
    15421 ttgatagctg ggataatctt ccatgaatat ccaatgaaag actctttgct ataaaaaaca
    15481 ttttgcccgt catgaaagta tacaacagga taggaacggt ctgtatcttt ctcataatct
    15541 ttaggaagaa gaatacgtac acggcgctcc ttacctgtat aaggaacctt gagtttgtgt
    15601 tctttcattt ttagataaaa gtaggattga ttcattgtca gaaaactctc tatattcaaa
    15661 attttatatc attatatcat gaaaatagaa aaaagctagt tttttacctg tttttagaaa
    15721 aaaaaactaa ctttttttac tgattttcgc tattcttttg gattttctga attagagtag
    15781 attatcaatc aagtcatcaa cttcatcttt ttcggcttga ggtgtgattt cagtaatcat
    15841 gattccagcc actgctcgct caaccaagcc ttcaacatcc atacgcgctt cgtactgctc
    15901 cgcattctta attttaggat ttgtttttgg acgatctggt gcaaaaatgg tacaacagtc
    15961 ttcaaacggt tggattgaaa tgtcaaaggt atcgatttcc tgggcgatgt caatgatttc
    16021 caacttgtcc atggtaacca caggacgaat gatgggagtg ttggtaacag cattgatagc
    16081 cttcatactt tcaagggttt ggctggctac ttgacctaga ctttccccat tgatgataac
    16141 caaaccattt cgtacctcac gaatacggtc agtaatccgc atcataaagc gacgagttag
    16201 agtcatcaaa taagcttctg gcgctttggc tttgatttcc tcttgaatct ctgtgaaagg
    16261 cacctcgata aactggatat ttccgccaaa cttggtcaat ttacgggtca agtcctgcgc
    16321 tttcttgagg gcaccaggac tagtatatgg tggactagca aagtgaactg cctcgatatc
    16381 caccccacgc ttaagagcaa gataacctgc tacaggtgag tcaatccctc ctgacaacat
    16441 gagcatccct ttacctgaag ttccaactgg caaaccacca gccccacgaa tggtttcata
    16501 agaaagatag gctgcttctt cacgaatctc cacctgaaga ttgatgtcag gacttttcat
    16561 ttgaacttgc acatttggaa tggcttcgaa tacagcccct ccaagtgttt ggttgagttc
    16621 acgactatca agttcaaagt tgtggtcgct acgcttgcta gaaatcttaa aggtcatacc
    16681 ttccttgtag atgtcccgca taatctcttg gacagaagac ttcaaaactt ctacagattt
    16741 ttcaacctta taaacaggag aaaagttttg aattccaaaa acttgtttga gagattctgc
    16801 aactgctgtg taatcagctc cattgaggta agcgtgggca cggtcgcgat ctgctgttac
    16861 cttaacttgg gtatagatag acaaaacgtc cgaaatatta ttacgaagtt tattgatgaa
    16921 acgcatacgg tttttaccct tggttgacaa ctctccgtag cgaatcataa tttctgaata
    16981 ctgcatgaat gctcctatct tacttttcta gtttgattgt aaatcaattt taacttggtc
    17041 aaaaactgct cgacctgact catatcattt tccaagtcta ggctaagacg cacagctgac
    17101 ttggccttat ctttgtccac tcccatggca atcaaggtac cggctggttt tcctgcctta
    17161 gatgaacaag ctgaggttgt tgagatgaaa atatcatagt cttcaaaggc gtgaacgatg
    17221 acttcacctc gaacaccttt gattccaaaa gtcagaatat gaggtgcaaa gtcttcctca
    17281 tctgaaaaga caaaaatatc cggatagttc agaagagctt ggcgaatcac tgccttcatc
    17341 tgcccagtct tgctcctaaa gatatctagc ttttccatag ataaacggaa ggccttggct
    17401 gtcgctgcaa tccctgccac attttcagtt gtcgaacgat aatctcgctc ctgaccacca
    17461 cctgtaagaa gaggtgtaat cttcttgcca gatttgatat agacaaagcc aacaccacgg
    17521 acaccatgaa atttatgact cgagaaggtc gcgcaatcca cccgttctgt cagatacttt
    17581 tcagtcggaa ttttggcaag cgcctgaacc gcatcaacgt ggaaggaaat agtcggcttg
    17641 tctgccaaga attctgaaat agcctcaata ggttggatag agccgatttc attgttcaca
    17701 gccatgatgg aaacgaggat tgtatcaggc cgtatcaaac ctgctaacac ctcaacatcg
    17761 acaaagcctt tcttatcaac tggagcaaaa tccacttcaa atccttgact tttcaaccag
    17821 agggctgact ctttgactgc tggatgttca atggctgaaa caatgatgtg cttgccaaac
    17881 tgagcttttt caaaggccac acccttgata acccagttat ccccttctgt tccaccagag
    17941 gtaaagaaga tttcatcgct tttcttaccg attaaatctg caatctgttg gcgagaagca
    18001 tctaagattc gtgttgcttg gtctcccaaa cgatggagac tagatgggtt tcctaaaatt
    18061 tttgaagcga cctgcatata ggtttcaagg gcttcaggat aaggcttggt cgtcgctgaa
    18121 ttatcaaagt aaatcatgtt tctcacgctt tctaaaatca ctccctctat tgtatcatga
    18181 aacggagctt gcgacaagaa agggcaattt ctcttttttt aagatttttt taaagaaaca
    18241 gagtataata aatcataatc aaaggagaga atgtatgtct aactatcgta gaacttcaaa
    18301 accgaaaaca gaacatatca aaaaaggctt tactgttttt caaaaaacca ttactactat
    18361 cggtagtatc cttggtttga ttaccgcggg tatcacgatc atgaacgcct tggataataa
    18421 taataaaaat actaaaaaag aacctacgac aagccagacg acaacctttg tcaaagaaat
    18481 tcaaaaagaa tcccctcagg aaaatactac tccaaataag gaaaataaga cttctcaaga
    18541 aaaaacacaa caagaagaaa cgccaaaatc cagcgtcaag gaagagaaaa aagaagagca
    18601 gaaaacatca actcaggatt cttctactcc tgctcctact ccaagtaaac ctgctactga
    18661 aaacgaaaaa cagtccaata ccccaacttc ggaaaataaa actaatcaat aatcactaaa
    18721 atagcctcct tccaaacttg gaaagaagct atttttttat tgttgtaaaa cttttcttgg
    18781 tttggtacct tcagctggac caatgacacc tgccatctca agctcttcca tgagacgggt
    18841 cgcacggtta aatccaactg acaaacgacg ctgaatcatg gatgcactgg ctttctgtgt
    18901 ttcgataacc aaagacttag cttcttcaaa aagcggatca ccaccagcat ctccatccga
    18961 aaattctcct tcattttcag aaacctcacc tggatcaaaa ctctcatcgt agtctgcatc
    19021 tgcctgagcc ttgatgaagt tcacaatgcg ctcaacatcg tcatccgaga taaaggagcc
    19081 ttggagacga actggatgat tttcatcaat cggtttaaag agcatgtctc ctcgaccaag
    19141 aagtttttct gctccatttt catccaaaat cgtacgggag tctgttcctg atgaaaccgc
    19201 aaatgctaca cgagatggaa cattggcctt aatcaaacca gagatgacat caacagatgg
    19261 acgctgagtt gcaagaatca tgtggatacc tgcagcacgc gccttctgcc caagacggat
    19321 gatagcatct tccacttcct tgctggccac catcatgagg tcagccaact catccacaat
    19381 cacgacaatg agtggtagcg gaatttgctt gtactcagac tgggaattga actcttctac
    19441 cttggcatta aaacctgcaa tattccgaac tcccaccttg gcaaagagtt cataacggtt
    19501 ttccatttca tccacaacct tttgcagagc cttgctggct ttgcgtggat tggtcacgac
    19561 tggaatcaag aggtggggaa tatcattgta aacagataac tcaaccatct tgggatcgac
    19621 catcataaat ttaacttgat ctggtctcgc cttcatgaga atgctagcaa taatgccgtt
    19681 aactgctact gacttccctg aacccgttga acctgcaact agcaagtggg gcattttaga
    19741 aaggtcaaaa gctcttgcgg ttccattaac agccttccct aaaggaattt ccaagaaatt
    19801 ttctgctttc gtttgcgatt gttcccatag ttctcggaaa gatacagtgg caatatcgga
    19861 gttgggcact tcaattccga ttagggattt cccagggatt ggcgcttcaa tccggacatc
    19921 cttggcagcc aaggctagag cgaggtcatc tgatagattg gaaatgcggt tgacccttac
    19981 accaacagcc ggcttgactt catacttggt cactgatggc ccaatttcgg cccgttcaac
    20041 tgttacctta ataccaaagc tagcaaaggt tgcttctaag attttgatat tttctctgac
    20101 aattttcttc tctttagact gatcttttgg tttatctggt gcaaagagtt gtaagcttgg
    20161 aagtttgtat tcaagggctt ctttggctga aaaatcgacc tgaacatctt cgtcatctga
    20221 gtcatcttcc tgttcaggga atttaagttc agcttgaggc aggatgattt ctggttccac
    20281 ccacttttct tctggaatag gtggaagatt ttgaacagct tcctctgtca gaatttcacc
    20341 cgtttccata tcaacaggag gcaaatcgag taaggctttt tcagtctctt cttgttctaa
    20401 tctagcctct ttctcagcct tttggcgagc tttttcttct tgtttgacaa agcgttcctc
    20461 ttttcgacgc tcgtgccctt cccaccattt agcaaagcct ctactgaaaa attcagcaat
    20521 atcgtaaaca gaccaagggc tgactaggag agaacccact aaaatcaaga tagaaccaat
    20581 aaagtaagtt ccgatatttg aaaagagaaa ggctgttgga atataaagag cgaccccgat
    20641 caagccccct ccagcaaaac tagtcgttcg aaaaccagtc agatctgtca caacctgagc
    20701 catggtccct tttagaacgg acttgtccaa accatatttc caaaccaagt aggcttcaaa
    20761 aatcaagagt aagccagcaa atatggtgaa aaagccagat aagagtcctt cctgttttcg
    20821 tatccacttg aaaaaaaaga gatagattaa taggccgaat atcgccagat aagctaggct
    20881 acccactagc aagcgaatta aattataaag ggttatacct gcagccccta atttgaaggc
    20941 tgcgaaaatc aataaaatcg caattcctaa tgaaatcaac attcgttgaa tcgcttcttt
    21001 tctttccagt tctgctttag acggtctccg tcttgttgta cttgtattct tgtttgccat
    21061 tcttctatta taccatattt cacaggcatt tcgggaagag aaaaagactg caccaaacgg
    21121 tccaatcttt tcatttttct attttttatg cttgtggttt gcgtaggtaa ccataaacca
    21181 caccacttac gattgctcct accaagacag aaacgaggta aaggagagca tttgaagtaa
    21241 gggcgataac gaagattcct ccgtgtggcg ccatgagttt gataccagta agaccaacga
    21301 gtccacctgc tactgctgaa ccaaggatga agcttggaat cgcacgagct gggtcagcgg
    21361 caccaaatgg aatcgctccc tcagtgataa atgacaagcc catgatgatg tttgtcaaac
    21421 cagagttacg ttcttcctta gtaaatttat ctttgaaaag aagagttgcg acaaagattg
    21481 caagtggtgg caccattcct ccagccataa ctgctgccat ggctacagaa ccacctgaag
    21541 aaacagttgc tgcaagcgta cctgtaccaa agacataagc tgctttatta actggtccac
    21601 ccatgtcaac agccatcatt ccaccaagga cgataccaag aaggacagct gaacctcctc
    21661 caagaccgcc taggaagtca ttcatagcag tgttgattgc tgccattggg atattcacag
    21721 ctagcataac aaatcctgtc aagattgttc caagaagtgg caatagaagg attgatttag
    21781 caccttcgag tgaacgagga actttaacgt atttcttgat ggcaagaacc aaggcacctg
    21841 cgataaatcc accaacaagg gcacctagga aaccagatga gacacctgca agagttgaag
    21901 ttgcttcacc acctgcggca taaggaattt taccaaaggc aaaaccttct ttggcaatag
    21961 caccagccac gaaacctgct accaaacctg gtttttcagc aatagagtag gcaacataac
    22021 ccgcaaagac tggaagcatc aaaccaaagg cagctccacc aattttcatg aacatagaag
    22081 ctaactcatg gtaagaacca agattgccaa ggttttcatt tggaacaccc aaagcaccgt
    22141 caatcaagaa ggcaagggca atcatgatac caccaccgat aacgaatggt aacatttgag
    22201 atacaccact catcaagtgt ttgtagaagg caccaccaag gctttgtttt tcgttagagg
    22261 ttgttgcagc ttttgcacca ttagcagcac ggtagatttc agcatcccca gaaagagcca
    22321 agttaatcag ctcttctgtt ttacggatac cgtcagcaac tggacgattg atcaatggtt
    22381 tgccatcgaa acgatccatt tcaactgcct tgtctgcagc gatgataaca gctttagcct
    22441 tgcggatgtc ctcaccagtt agttggttac caacaccgct agcaccgttg gtttcgacct
    22501 taattccaac acccatttca gcagccactt tttgaagagc ttcttgagcc atataagtat
    22561 gggcaatacc tgttgtacaa gctgtaacag ctacgataaa gtcaccagag ttattggcaa
    22621 gtgcttgagc aggttcctca gttttttcta aagcttggtc aaaaagttca atgacttggt
    22681 cagctgatgt tgcttgacga agtttgtcag caaaaccgtc tttcatcaag tattgagaca
    22741 attctgccaa ggctgccaag tgggtgtcat ttgcaccttc tggagctgca atcatgaaga
    22801 agaggtcagt tgcctgccca tccaaactct catagtcaac acccttgttt gacttggcaa
    22861 agagaactgt cgcttctttg acagcagcgt ttttgctatg aggcattgcg ataccgtctc
    22921 ctaaaccagt agaagtcaag gcttcacgcg ccaaaattcc ttctttaaag gtttcaaaat
    22981 ctgtcacata cccgtggtct accaagcttt taatcatctc ttcgatgaca gcagtttttt
    23041 cagttgcctg caaatcaagc aacataacat cttttctcaa taggtcttga attttcatcg
    23101 tttttctacc tcaacttttt catatgtttc tttaataaat tctgctgttg ccaagtcatc
    23161 cgagaaggtg gttgccgttc cgcaagccac tccccatttg aaggcttcta ctgcgtcttt
    23221 tgatttgaca aattcacctg taaatccagc gaccatagaa tcgccagctc cgactgaatt
    23281 tttcactgtt cccttgattg gtttagcgaa gtaagctccc tcagatgtga caagaagggc
    23341 accgtcacca gccatagaga taatgacgtt ttgagcacct ttaaccagta actcacgagc
    23401 atatttttca atttcatcta aactatcgag ttcaactcca aagatagctc caagttcgtg
    23461 attatttggt ttaaccaaga gcggttggta ttccaaacta tcaatcaagg tctgtccttc
    23521 aaagtcacaa accacttgcg caccagtctg acgtgtcaag gtaatcaaat ccttgtagat
    23581 gacattgcct agatttttag cacttgaacc cgcaaataca accgtatctt ctgctgtcag
    23641 actcgataaa atatctttca actcttctag ctgagccggt tcaacagttg ggcccgttcc
    23701 gttgatttct gtttcttggt ctgctttaat cttgacattg atacgagtat cttctgccac
    23761 ttggacaaaa cgtgtctcga tttcttcctt tgccaaagta tctgtgataa atttaccagt
    23821 aaagccaccg ataaatcccg tcgctgtatt tggtatatcc aaacgtttca agacacgact
    23881 gacattgatt cctttcccac cagcaaactt atcatcactg tccatacgat tgacactacc
    23941 gacttgaact tggtccaagc gcacgatata gtcaatagat ggattgagtg tgactgtata
    24001 aatcatactt ctattacctc cgttttctcc ttaatagcct gcaagagctc atgcccttga
    24061 cttgtgataa caatagcgcg tttgagtggt gccaccttgg caaagcaagt ttgtccaatt
    24121 ttagacgaat ccaccaagac ataggtctgt ttggcatttt ctaaaatagc acgcttcaca
    24181 gctccctctt ccatatcagg agtcgtataa taaccatcgt ccacaccatt catcccgata
    24241 aaggcacggt caaagtgcaa ttggttaatc tggttaagag caacgccccc gatactagca
    24301 tctgtcgcca tcttgacact tcctccaacc atgacagttg gaatctgctt ttcaaccaac
    24361 tgagcggcat ggtgaatcga atttgtcaca acagtaatat tcttattaac caattcatga
    24421 atcaaaaaag cagttgttgt tccagcatcg ataaagatga catcttgttc cttgatgaga
    24481 gaggctgcct tctgagccag caacttcttt tcttgaaggt ttttgacaga tttttcttga
    24541 atggtttctt cttcctgcaa ggaatggggc aattctgctc caccatgcac gcgacgaagc
    24601 ttgttttccg cttccaactc atccaaatct cttcgaaccg ttgattctga cgtttctaac
    24661 aaactaacta atttttctag agaaactaca tgatgttgat ttaactcctc taaaatcagt
    24721 tgcttccgct ctgtttttaa cactgaatca cctcctgtta tcgtttacac tattcattct
    24781 atcacacttt ctttcaaagt caagcgcttt ttgtcatttt ctttcaaaat ctatcatttt
    24841 tcttatttcc aaaattttta ttgcaagata agagccttta tggtagacta tttgagtaag
    24901 tattggaaga ttactcaaga ggcttaagag gccgtgttgg aaacgcggta ggcgtgtaac
    24961 agcgtgcgtg ggttcgaatc ccatgtcttc cgtttatttt aaaaaagata cccaagaaat
    25021 cttgggtatc ttttttctta tatgcttgtt ttataactcg ggtgaatttc ttagaaaata
    25081 tcaaataaca atttcacatt gagaattgtt aagataatgg aaacgatata gccaaggatg
    25141 gtattccatt tggcattggt aaattctccc atcagtgatt tcttagaagt tagataaatc
    25201 agtgggaaga ttgaaaatgg aagagcaatc gaaagaaaga cttgtgaata aaccaataac
    25261 tgatctaatg ttttttcctg atgaccaaac agaaccgcta caatcatgac aggcaacaag
    25321 gcaaagagac gagttgccaa acgaatgaac cattgaggta atctcatatg caagaaacct
    25381 tccataacga tttgtccagt caaggtaccc gtaattgtcg aattttgacc actggctaat
    25441 aaagccaagg caaacaaggt tgataaggtc gagctagcta tagctcctgc aatagtagaa
    25501 tcctgcaagg cattatacat ttgagagaag gcagaaatct cagatgcatg gccgaaaaag
    25561 agagccgccc cgagaattaa tagaagggag ttaaccacaa aggccaagga taattggaga
    25621 tttgaatccc aggtcataaa gcgcacggct tttcgaacat cattcttgtc cttgtgattg
    25681 attttccgag tttgagacaa ggaagaatgc aaatagaggt tatggggcat aaccgttgct
    25741 cccacgatcc ctagtgccaa ggttaattga ctttcatgcc ctggcaaggg actttcaaat
    25801 aaggttgcat tcggtagata accctcaacg attccttgga agcttggatg tgacaaagct
    25861 accagatagg taaaaattgc tagaatggtt aaaatcagtg ttgtcacaat agcttcaatc
    25921 ttcttaaagc caaatttcat cagaagcaat aagagaaaaa catccaacac ggtcaagaga
    25981 attgctatca taatcggaat cttaaagaga agattgagag caatcgctga acctagaact
    26041 tctgccagat ctgtcgccat caaggctaat tctaaaatca cccatagact ataacgaagc
    26101 catttaggtg aatgatgagc cgttgcttga gccaggtcca tctgggttac aataccaagc
    26161 tttcctgcca tctgctgaag ttgcatggca atgagagatg aaatcaagat aacaaacaag
    26221 agactatact tataggaagc accaccgact acactggtaa tccagtttcc tggatccata
    26281 taaccaactg cgacaagagc acccggacct aaaaaggcat ttaaattttg ccagaaatga
    26341 ttgttatttg gagtatcgat agattgatta atctcagaga gtgacacttt tttatgagaa
    26401 gacatagata cttacctctt tctaaaccta ctttttcatt attttctatt agagaaaaat
    26461 aagattgact ttaaactatt aaaacaatga aaactatatg aaaaacattt agttttttca
    26521 ttatttttct taaggcacct taattataac agaaaatatg ataaaaactt aagaaaattc
    26581 aggacttgat ttaatattta ggatacaaca aaatgttgta ttcttttttt gcaaaagaat
    26641 accaaagaat aaaataaaaa acgttgtaaa aacaacgttt tagaaagatt tacaaaacaa
    26701 tgtaaattat caatggagcc ggtgggagtc gaacccacgt ccaaacatct gctaacatat
    26761 ttgtctacaa ccataggtta tgtattattt taacagcccc tcgacacata actcaagtct
    26821 agaaactgcg agtctatcaa tctcttatca agccgctaga caaggcttaa tcgtatctcg
    26881 ctaataataa gacctgtcat tgaacacgag caatccaaat cgggtcacgc ctgctggttt
    26941 ttaggcagct agagcgtaag aagtgttatt ttttgcagtt atatttaact gagcgtttac
    27001 gtcgccacac gagtcgcaaa atatgcctca taatgcctgt cgaatccgta acgaccccaa
    27061 aagacaataa aaccattata ccttatctaa ctcaaaaatg caaaaagaaa tcacatacct
    27121 aaaaaagata ctattcgaga aatttagcaa actggaagac taactacaac tttttcagtg
    27181 cataacttta cgattgtaaa tagagcttac gaaatccaat taacacatac ctaagatgaa
    27241 gctatctgtt ttgaagaaat tcacgaagag aattattcta aaatactttc agatgagaat
    27301 tttcgtactc tctttatttt aattcatttg agtttaaaaa ctataaaatc aatccttata
    27361 ttattcggac tacttttcac ttattgcacc aaaatatagt aaaatgaaat aagaatagga
    27421 cgaatagatc aggacagtca aatcgatttc taacaatgtt ttagaattag aggtgtacta
    27481 ttctagtttc aatatactat aaataggttt cattcgaact ttaatagact atgaaaacca
    27541 gtggaactta ccctgacacg gaattccact ggttttttcg atttttatca gattaacttc
    27601 tactattctt agctgtgaaa attagtttaa gactttaact tattttcagt cttctaatct
    27661 aaaggccact tccagtaaag aaaaatcagg gttctcctga cttttactta gctaattctc
    27721 tttctcgttc tttcattatt ttatgatttt catacaaacg ggataagaac ttagaaattt
    27781 ctttcaagat agaataggtt ggcactgcga caatcattcc aactacacca tagatattgc
    27841 ttgacaacaa aagtaaaact aaaatcgtga ttggatgaac cttcataaca cttcctacaa
    27901 ttcgaggata taagatattg ccatctacct gctgaacaac aagcatataa atcactgcaa
    27961 tcagcagtct atggggatca gtgaatatat ttgcgatgat cataggaatc aaaccaatac
    28021 ttggccccac ataaggaatt aaattggcta caccagaaaa aatggcaaaa actaaagcat
    28081 attttaaacc aataatacta tagccaatat aagctaaaca acctataatg attgcgtcaa
    28141 tcgaaactcc actaatatag cgagcaatcg tcgcatttaa attctttaat aagcctgcaa
    28201 tatgcaagcg atccctcttt agaatcgttc tttcaagcat gggcaagaat ttatgtccat
    28261 ctaataagaa ataaaccaaa aaaactggag tcataatcaa aatcaaaaca gtactgataa
    28321 gagctgacaa gacgctcccc acactatttg atacgctatt taggatattt tgaagaatat
    28381 ccacatagga taagtttaac tgctgaattg tagcttctac atccaaattc tggagcgcag
    28441 gataattaga taagtctatg attaagtctt gtactcgact ataaatagtt tgactagata
    28501 taatcaaact agataactga ttaatcaaaa taggtaagag atagacaaca cctatgacca
    28561 ttccccagac caaagtacac aaggtaatta aaataccaag caaacgattg agtttacaga
    28621 ctttatttaa gaaagtaaca atagggtttg tcaaataata aagaaagccc cctaataaaa
    28681 atggaatcat aattgtatta agcacgctaa caaaagggtt aatcaaagac cccatctgtc
    28741 tccataggta aaagatgatg gttaagagta aaatttctgt ggtccaaaaa aataatttat
    28801 ttctacgaaa catgagttac ctccctcact ttattttacc atattttcaa aaagcttaac
    28861 agatgaatta ttaaagcaag aatatttttt ttctttatga tagaataaga ctactatgaa
    28921 aaaaatattt ttaactttgt taactgtctc tcttttaggg ggtgcttcta ctgctgttgc
    28981 tcaagatttt accattgccg ctaaacatgc gattgctgtt gaggcaaata ctggtaaaat
    29041 tctctatgag aaggatgcaa cgcaacctgt cgaaattgct tccataacaa aattgattac
    29101 tgtttatctg gtctatgaag ctttggaaaa cggaagtatt accctctcca ctcctgtaga
    29161 tatttctgat tatccttatc aattgacgac aaattctgaa gccagtaata ttcctatgga
    29221 ggcccgtaat tatactgtcg aagagttgct tgaagcaact ctggtatcta gtgccaacag
    29281 cgccgctatt gccctagctg agaaaattgc tggctcagaa aaagatttcg tcgatatgat
    29341 gcgggcaaaa ctcttggaat ggggaattca ggatgccact gttgtcaata cgacaggtct
    29401 taacaatgaa actctagggg ataacattta cccaggttct aaaaaagatg aggaaaataa
    29461 gcttagtgct tatgatgtcg ctatcgttgc tcgcaacctc atcaaaaaat acccacaagt
    29521 cttagaaatc accaaaaaac cttcttctac ttttgctggg atgacaatca cttcaaccaa
    29581 ctacatgtta gaaggtatgc ctgcttaccg tggtggtttt gatgggctaa aaacaggaac
    29641 aacagataag gctggagagt cttttgttgg tactactgtc gaaaaaggca tgagagtcat
    29701 cacagttgtt ttaaatgcag atcatcaaga caataatcct tacgctcgat ttacagctac
    29761 atcttcccta atggattata tttcttctac atttacactt cgcaaaatcg ttcaacaagg
    29821 cgatgcctat caagatagca aagcccctgt acaagatgga aaagaagata cagtaactgc
    29881 agtggctcca gaggatatct atctaataga acgtgttggg aatcaatctt cccaatctgt
    29941 tcaattcaca cctgattcca aagcaatccc agcaccactt gaagctggaa cagtggttgg
    30001 ccatttgact tatgaagaca aggacttgat tggtcaaggt tacatcacca cagagcgccc
    30061 tagtttcgaa atggtagcag acaagaaaat tgaaaaagcc ttcttcttaa aagtttggtg
    30121 gaatcagttt gtccgttttg ttaacgagaa attataaaaa atcgcgattt taaaccgcga
    30181 ttttttgata caagttcatc ttcaaaatca aagaacaaac taggaagcta gccgcaggtt
    30241 gctcaaaaca ctgttttgag gttgtagatg aaactgacga agtcagtaac catacatacg
    30301 gtaaggcgat gctgacgtgg tttgaagaga ttttcgaaga gtataaaatc aaattttatc
    30361 caactgatcc ctccatttca tagctaatca agcggttcag ctcaactgcg tattccattg
    30421 gaagttcttt tgtaaagggt tctacaaatc ccatgacaat catttcagtt gcctcagatt
    30481 ctgacaatcc acggctcatg agataataca attgctcttc tgaaatctta gatactttgg
    30541 cttcgtgttc caaagccact tgcgagttgt gaatttcatt aaatggaata gtatctgatg
    30601 ctgacaagtc atccatgata atggtatcac attcaatgtg ggaaacagat ttcttagagt
    30661 tcttgttaaa ggtgacttgt ccacggtagt caacctttcc tccaccttta gcgatggatt
    30721 tagacacaat agacgagctg gtatgtggag cattgtgaat catcttagca cccgtgtctt
    30781 ggtgttgccc tgcattagca aaggcgatag agagcatggt accacgcgct ccttctccat
    30841 caaggtaaac agatggatat ttcatagtcg ttttggcacc caagtttcca tcaatccact
    30901 caacagtggc atccttttga gccttagcac gctttgttac caagttatag acgttatcag
    30961 accagttttg gatagttgta taacgcatat aagctccgtc caaagcaaaa atttctacaa
    31021 tggcagcgtg taagctattg cttgaatatg ttggtgctgt acatccttct acgtagtgga
    31081 cgcttgctcc ctcatcaacg ataatcaagg tacgttcgaa ctgacctata ttttcgttat
    31141 tgatacggaa ataagtttga agtggaatat ctaccttgac accttttggc acgtagataa
    31201 aagttccacc cgaccatact gctgagttga gggctgccaa cttgttatct gtcggcggta
    31261 ccaacttcgc aaagtattga ttaaataagt ctgggtattc cttgagtgcg gaatctgtat
    31321 ctgtaaagat aatacctaat ttttggaact cttccttcat gttgtggtaa accacttctg
    31381 actcgtactg ggcagaagcc cctgctaaat aagcacgttc agcttctgga atcccgatac
    31441 gttcaaaggt ttctttaatc ttttcaggta catcatccca agaacgggct ggtttgtcag
    31501 atggtttttg gtagtagatt aagtcatcaa agtcaatctc tgacaagtct gctccccaag
    31561 tttgcatggg catttttttg aaggtttcat aagacttcaa acggaactcc aacatccact
    31621 caggctcacc cttagcagca gataattcac gaataacacc ttcgttgagt ccttttcctg
    31681 tcgataagac aggctctaca tcgtcatgga aaccaaattt atattcacca aggtcaattg
    31741 gttttggttc tactctttct tcagccatag tatcctttct ttcttcattt ctaataattc
    31801 ataagacaaa agaaacttgt cttactgttt ttcttgattt tcaattgttt tcttaagggc
    31861 attccaagct agggttgcac acttgattct ttgagggaat ttggcaacac ctgacaagaa
    31921 tgccgcgtct ccaagttggc cttgacgctc atctttttgc ccttgaacca tttcagaaaa
    31981 aatagtcgcc agttctaaaa tttcttgttt ggtttttcct aaaacggcat ctgtcatcat
    32041 actagcagaa gcagttgaaa tcgtgcatcc tgaatttaga aaagcaatat cttccaaacg
    32101 gtcctctgca tcaaacttga cagagaggtt gatgacatcc ccacaagtcg gattgttgag
    32161 actggtttgc tcagcatctt ctaacttccc ttggtgatgt ggatttttcg aatggtctgc
    32221 taccactgcc atataaaggc tatctagttt agaaagtgcc attgaaaaac tcctttgtct
    32281 tttgtagggc atcgactagt ttgtcgcaat ctgccttggt attgtagata taaaaacttg
    32341 cacgagctgt tgctgggact tccaaatact gaagcaaggg ttgcgcacaa tggtgaccag
    32401 cacgaacagc cactccttca taatccagag ccgtcgcaag atcgtgagga tggagatcac
    32461 ctaggttaaa ggcaataaca cccgaacgtt gagccaaatc ctgagaaccg taaatggtca
    32521 atccctcaat tgcctgcagt tttggataga cgtacgcaat caattcctgt tcatgagctt
    32581 caacggcatc cataccaatc ttttccagat aatcaactgc agtcgcaagt ccaatagctc
    32641 ctgccatatt tggcgttcca gcctcaaatt tccaaggcaa ttccttccaa ctagcaaatt
    32701 gctcgtagac aaaatcaatc atctcgccgc caaattctac tggagacatt tgctcaagat
    32761 acttttcttt gccgtaaagg acaccgatac cagtcggacc agccatcttg tgacccgaaa
    32821 aggcgaaaaa gtccagatcc aagtcctgga catcaatctt catatgaggt gtagattgag
    32881 caccatccac taccataatt gccccaactt ggtgggctaa ttgagtgatt tccttgatcg
    32941 gattgaccac accaagaaca ttggaggcat gagctaggga aacaaattta accttatcag
    33001 tcaatttagc tcgcaaatcc tccatatcca aggcaccgtc tttaagatag acatagacaa
    33061 gctctgctcc agtctttcga caagcttcct gccatggaat gatattagaa tggtgttcca
    33121 ttactgaaat caagacctgg tctccctcag cgagaatttc ctcagcaaag cgtgccaccc
    33181 agttaaggct ggttgtcgtt cctctggtaa agagaacttc ctttgtagag cctgcattaa
    33241 taaacttacg aatggtttca cgagcagctt cataagaagc tgtcgctcgt tccgctaagg
    33301 tatggacacc acggtgaaca ttggcattgt cctgctcata gtaactgtta atagctttca
    33361 gaactactag tggtttttgt gtcgtcgcag cattgtccag atagaccaga ggttcatcat
    33421 tgacaatctg atctaaaatt ggaaaatcct tgcgaatcgc ttctacatct aacataggct
    33481 tccccttagc gttttgacaa tttctcttcg atagttgcaa tcatttcatc acgaacttcc
    33541 ttgactggaa tctccacgat aacagatcca aggaaaccac gaacaaccaa acgctctgca
    33601 gttgccttat ccaatccacg actcatgagg taatacatgt cttctggatc aacttgtccg
    33661 atagacgctg cgtgtcctgc agtgacatca ttttcatcaa tcaaaagaat tgggttagca
    33721 tctgaacgcg cttggtctga aagcatgaga acacggctct cttgttgggc atctgctccc
    33781 ttagcaccct tgatgatgtg gccgatacca ttgaaagtca aagttgcttt ttcaaggata
    33841 accccatgtt gtaggatatt tccgatagag ttgcagccat agttagttac acgagtatca
    33901 atcccttgta cctgacgacc acttgaaaga gctacaacct tgaggtcagc atggctacca
    33961 ttaccaatca agtcactatc aaaatcagca acgacatttc cttcgttcat gacaccgata
    34021 gcccagtcaa tacttgcatc gttgcctaat ttaccacgac ggctaatgta ggcagtgacg
    34081 ttttcaccta gacggtcgat agcagcaaac ttgacttgcg cacctgaacg tgcaatcact
    34141 tctactgtga tattagcagt tgctttggca cttccttcac cgcgtgactc taaacgctcc
    34201 agataattaa tcttagaatt tttaccagcg ataatcataa tatgcttgtt aaacggcaca
    34261 ttgctatcgc tatcttggta gaaaattcct tcaattggct ctgtgatttc tacgttatct
    34321 ggaatataga gtacagcacc actgttaaag taagctgtgt ggtaagccgc caacttgtca
    34381 tcatcatact taacagatga catgaagaat tcttcgatca gctctggaat ttcttctaaa
    34441 gctgagtgaa agtctgtgaa gacaacaccc tgttcagcta actcaactgg agtttgttcg
    34501 aaaacagttt gagttcctac ttgcaccaac ttcaagtgat gatctaaagc tgtgaaatct
    34561 ggaacatttg ctgatggctc attttctgta atcgttccat cacccagatt ccaacggtgg
    34621 aatttgacac gctcaataac tggtaattcc aaagtctcaa tcttgtcaaa agctttttga
    34681 cggagatcag ccaaccagct tggttcagcg tgcatttctg aaaaaagttt aatattttct
    34741 ctagtcattt acttctccta aaagatacga ggaaattaca attcttcctt gtagtcgtag
    34801 ccaagttctt cagctaattt tgcgtatcct tcacgttcca aacgcgcagc caattctgga
    34861 ccaccagaaa ggacaacacg accttccatc atcacgtgta ccacatcagg tgtgatatag
    34921 ttcaaaagac gttggtagtg agtgatgatc atagcaccaa aaccttcacc acgcatggca
    34981 ttgacacctt tagacacaac tttaagagcg tcaatatcaa gacctgagtc aatctcgtcc
    35041 aaaagagcaa atgttggctc caacatcaaa agttgaagaa tttcattgcg ttttttctca
    35101 ccaccagaga agccttcgtt gaggtaacgc tctgccattt cttctttcat gttgagcaat
    35161 tccatttttt catctagctt agtaataaac tcacgaactg aaatcttctc atcatcttct
    35221 ttacccgcat tcatagcggc acgaagaaac tcagcattgg taattccagg gatttctgat
    35281 gggtattgca tagcaaggaa aagtcccata cgcgcacgct catccacttc caactcaagg
    35341 atgtttacgc catcaaacaa aacttcacct ttagttactt catagtttgg atttcccatg
    35401 atagcggcag aaagagtcga tttacctgta ccatttggtc ccatgatagc ggcaatttct
    35461 cctgttttca gggtcaggtt aacccctttt aaaatttctt ttccttcaat ctcaacgtga
    35521 agatctttga tctctaatac tgacatgata gttcctttct ttttcaaaac ttttacagta
    35581 cttactagaa aaacgtctga tttccccaga aatagagcaa aaattctata aatatacttt
    35641 tctagtataa caaaaaaaag cctaaaaggc tttgattttg tctggaagct gagggctagt
    35701 ctttcctatt aaaatgctga tcgatgacat caacgatttt gcccatcaca taactgactc
    35761 ggaaatttct aaagagtaaa attgcccaaa aggctgccat aatatagcgg ccagtcatcc
    35821 aggattcatt gaaaaaatag gtctcagcag ctgtaaacag cgccataata ataaattgtt
    35881 gtttattcat aaacttattg tatcatgaaa tctttcttta gtcttcctct accttcactt
    35941 tatcagccaa aaattcaaat ccttctggaa tcaggctttc ttctacttct ttttcagttt
    36001 gagaagattt ggcttttgct gaaaaggctg cgcgaacttc tttccattcc tccatggaaa
    36061 tagctaaaat ctcaggtgaa aaacctgccg cctgactgag gatattacca aacatggtat
    36121 tgagattgtc tcgtttcata gtttgaccag cattgaagtt agactcaaaa gcaagaatag
    36181 catggtgttc attggcagca accggttgag aaccaactag cagagccttg tccggcccac
    36241 ctagactttc aattacctct ccccatgcat tctgcaaacg aattagattt tgacgtgcta
    36301 aatcaggatt ttcgacggcc tcctgtaaga tagattgtac tttattgcga tcgacacgat
    36361 agactgtttt gcccgtagct ggtcgactag gagctggtgc aacttgttta ggaaccgcac
    36421 ctacattaga aagctcttgt ttgagacggg caacttcctg tctcagcgta gcaatttcat
    36481 tttcaaccgc tcctgataga gctggttcgg gcttgatttc cgccaaacgg acggtcatca
    36541 tttcagcata aatcttgggc tgcaaactag acttaatatc tgctaaactc actgttgcta
    36601 agcgaatcat ttcaaacaga tttttttgag gaagtgccaa attttctaca aagactgaac
    36661 tatgatgagt attttctccc cctgtttgaa caattaacaa gtctcttaaa tagtgcaaaa
    36721 gatcggtcac aaaacgagtc atgctcttac cattgtcaaa aagaagattc aagcaagaca
    36781 aagctttggg aacatcctgt tgagacaagg ccgccacata atcatccaag gctgataggc
    36841 taatggtgcc agtaatttct tcagagatag cagtcgtcag ctcatttccc tgtgtcaaac
    36901 tcagggcttg atccaaaata gacaaggcgt cccgcattcc accttccgcc cgtctggcaa
    36961 tgatttccac agcctctggt tcagaactga tattttcttt ttctaagata tagtgaatat
    37021 gttccttaat atcctgtgtc ttaattgatt taaactcaaa acgttgcaca cgggatagaa
    37081 tagtagcagg aatcttgtgc aattcagtag tggccaaaat aaagactaca ttctgtgttg
    37141 gttcttccag cgtctttagg agggcattaa aagcccctgt agacagcatg tgaacctcat
    37201 ctatgatata aaccttataa cgagcaaggc taggcgcata ggtagattta tcacgaattt
    37261 cgcgaatttc atctactcca ttattagaag ctgcatccat ttcaatgaca tcttctaaac
    37321 taccgtccgt cactgcttga caaatatagc agttattgca aggttcgcca cccacttgat
    37381 tgggacagtt catagccttg gcaaagattt tagcaacact ggtttttccc gttccacgag
    37441 gaccagaaaa aagataagcg tgacttattt tctcttgctc caccgcttgt ttaagagtct
    37501 tagccacaac ttcttgacca actaactggg agaagttttg acttctatat tttcgataaa
    37561 gtgcttgata cattaagatt tttcctcaaa catcgtaaag tcccatgttg tcttttcaag
    37621 caaaatagcg acaaattgtt ccaaataatc tcgatccata gcatcgtaat cctcaatctc
    37681 tgaagaatcc agatccagaa ctccaagtaa ctgaccattc ttcatcatcg gcaccacaat
    37741 ttcactttta gctagactat cacaagaaat atagttgaga taggtcgtca catctccaac
    37801 aataacagtt tcctgaaagt gagctgcctc accacaaaca cccttgccta gtgcaatacg
    37861 gatgcaggaa acacctcctt ggaagggacc taaaaccaat tcctttccat cgaacaaata
    37921 aaagcctgca aatacggtat taggaaaacg tgattttatg agagcactgg cgttggaaag
    37981 attagccaaa acattggttt cgccttccaa taggaaggac aattcttcat ttaacatttg
    38041 ataacgtgat tgtttttctg attttaacat agaactatta tatcaaaaaa ggagcagaga
    38101 caaaagaaaa atcccttgtt tagtaaacaa aggattttgt gaattttcaa tttgattaaa
    38161 gttcgatatc accaaacaaa tcagccattg aaaatcctgt ttgtgtttct ggaagttcga
    38221 aatcacgctt ttcttgacgt cttggacgac gtggacgagc agcacgtttt tcttcttttt
    38281 gtccttcttc ttggactgga cgttcttcaa gagctttaat agaaagtgac acgcgttctg
    38341 catctgcgtt aacttcaaga actttaactt gaacttcttg accaacttta agagcttctt
    38401 ttggattttc aatccgtttg tgtgaaattt gtgatacgtg aacaagtcca tcgatacctg
    38461 gcaatacttc aacaaatgca ccgaagtcag tcaaacgttt aactgttcct tctactacat
    38521 cacctttagc caatttttgc tcaacgccat cccatggtcc tggtactgtt gctttaagtg
    38581 aaagtgatac acgtccttct tcttcgttaa gatcaaggat tttcacttca atttcttcac
    38641 caacagttac aactgatttt ggtgatacgt tacgttcatg tgacaattca gtcaagtgaa
    38701 ccaatccgtc aacaccacca aggtcgatga aagcgccgaa gcttgtgata cgagcaactt
    38761 taccagttac aacatcacca acagccaatt taccgaatac ttcagcgcga gctgctgcag
    38821 tagctgcttc aacaacttca cgacgtgaaa ggatgaagcg gttttcttta gcgttaactt
    38881 ctttgatttt agtatcaaat tcttgaccta caaaacgctc agcgttacgt acgaaacgag
    38941 tatccaacat tgaagctggg ataaatccac gaacaccttc aaattctact gaaagtccac
    39001 ctttaacggc acgcgttcct ttaacagtaa caacttcttc ttcgcgacca acaagtttgt
    39061 cccatgcttt gcgagcttca aggcgttttt tagatacaag gtatgtaact gtatcagtat
    39121 ctttaccaac tacttgacga agtacaagaa catccaatac ttctcctact ttaacaaagt
    39181 cattgatatc tgcatcacga tcgtttgtca attcgcgaag agtcaagaca ccttcaacac
    39241 cagttccaga gattgcaacg ttagcttgag tcgcatcaac tgtcaatact tcagcactaa
    39301 caacatcacc agtctcaact tgactaacgc tatttagcaa atcttcaaat tcgttcatct
    39361 aaaaaatcct ccaacaatca agtttttctt aaacttgaca tacttataat ttttttccta
    39421 agcacccgca aggacatgtt catatcattc acgtctttca attataaaaa taaaataccc
    39481 taagatattt tgctttctat cttgattatt acctaagaac tggggtagct ggattcgaac
    39541 caacgcatga gggagtcaaa gtcccttgcc ttaccgcttg gctatacccc attaatgaaa
    39601 tggagagaga gggattcgaa cccccgaacc cgaaggagcg gatttacagt ccgccgcgtt
    39661 tagcctcttc gctatctctc ctacaatcaa catggactat tatatcatga aaatttcaaa
    39721 aaaacaagac ttattttgct aaattataat tttcaatcaa aatttccaca gctttttcca
    39781 attttttata aaaactatcg acattcccat tctttataat ggcaaattgt ccgtctaatt
    39841 cggcaatttc tccgataact tttttaccga tagtcaatgt ataaccttca aaactgtctt
    39901 taccaacatt aactttggca tccgctactt gaatttcgat ttttttatct ttcttgctca
    39961 tttcatacct ctcttcactt tttctatttt acaagaaaat cctaaaacta gcaagaaaaa
    40021 actctatatc aggcttctct gatatagagt tttatgtaaa caacctcaat tgatttagca
    40081 tagttaatag ttagtaaaca agcataattg actatccttt ttaggttatc agtgagtctc
    40141 accgcctact aactgcaaat ccttatcttt gtagtctaca atagcttcaa tagctacctc
    40201 tatgcctctt acaatatcac atagactcat tcctgcagta ttcggcttat ttactacttg
    40261 ttccatcata tatggaatat gcatgaaacc tgctctcata ttagggaatt ttttatccac
    40321 taaataaaga gcttggtaca tcaaatgatt gcaaacaaag gttcctgcac tattggatac
    40381 aactgccgga agtccctgtt ttttgatagc ttgtaccatc gctttgatag gtaaactact
    40441 aaaataggcc gatgctccat caatacgaat cggtgtatca attggttgat tgccttcgtt
    40501 atcaggtatg cgagcatcat cttgattaat agccactcgt tcaggtgtta agccggtcct
    40561 gccgcctgct tgtccaatac aaagtacagc atctggttga tatcgtaata tttctgcctc
    40621 taaaacttct gacgacttat aaaaaaccgt tggaatttct acccagcgaa cttcagcccc
    40681 attaatctca gatggtaata attttacagc ctccaaagct ggattaatct tttcacctcc
    40741 aaaaggatta aaacctgtaa ccaatatttt cattttattt tcctttacta aaatgcgaga
    40801 aagtacatta agaatatgtg aataacaatc attactagag caacacctgc ttgagccttt
    40861 ataacgccat tctgatcttt catatccatc aatgctgctg gtagagcgtt aaaattagca
    40921 gccattgggg tcaataaggt cccacaataa cctgctgtca tggcaagagc accagccaca
    40981 attggattag ctcccagagc aaatacaaag ggaactccaa cacctgctgt aataacggtg
    41041 aatgctgcaa aagcatttcc cataatcatt gtgaatagaa ccattccaag aacataagcc
    41101 aaaactccta taaagcgact atctgaagga acaataccgc taatcagatg agagataaca
    41161 tcaccaacac ctgctacagt aaaaatagcc cccaaagccc ctaataattg aggaacaatc
    41221 ccacttgttg aaacttgctg agtcattcga ttattttctg ataacagact cttagggtga
    41281 ctattggtaa tcacaagaac agaaattgta gcaaacaagg cggcaaggct aatcgaaatc
    41341 ttgctaaatt ctggaatcat ttgcgctaag accaacgcaa gtattgccat cagcataact
    41401 ggaataaaaa ttttattttt caacctgtta gattcaatat tggctttcat ttcatctaag
    41461 gatggcaagg ttccgatacg gacttgctta aacaatgtta acagcgataa taggattaca
    41521 ataataccaa tactcatatt tggcatatag gaaccaccta taaacgtaat agacaataga
    41581 gtccaaaatg cagatgtccc aagtcgaact gggtttgttt tatctttata actacaatag
    41641 gctgtatgga gaaattgaca accaatcaca atataggtca actctaatag ttgctttgcc
    41701 aactctgtca tttttgttct cctcccctag tcttttttga tatcaatttt ttatcaaata
    41761 aataattgta aatccccact acaataagtg ttataacagc aacaataata gatgtagaag
    41821 caatccctgc ataattgctt tcatagccta actgatctaa tgttccccct atcaagagga
    41881 ctcccccagc acctacaaac gtattttgag caaagaaatt tccaaaattt tcattcgcag
    41941 ccgcacgcgc ttttattgtc tcatcttcaa cctctgttaa ctttctacct aattgagact
    42001 ctgcagctgc ttctcccata ggttgaacca aaggtctgac aaactgaggg tgtcctccta
    42061 gacgaattga aaagaaacca gctaactctc gaataaagaa ataaactgta tagaagtttc
    42121 caactgtcag acctttaatc tttcgaatca aatcgattga tcgttgcttg agtccaaagg
    42181 tttctgacag ccccacaaga ggcaaggtaa ccataaaaat cgtgagcact cgctgattgc
    42241 taaattcttt tcccaaaatc tccaaaaatt caacgagaga aacacctgaa actaaagctg
    42301 taaccaaacc agctaagact actgttgcaa ttgtatcaaa ttttaaaata aaacccacaa
    42361 caatgattgc tattcctatt aatctaatcc actccatatc aaactccttt atattcaaaa
    42421 tgacagtatt ttaaaaattt tatcaagatc aataccattc cttatttaat gtatttttct
    42481 agttcttttt ggtatttgct attggattcc aatttttctt tttgccattt tttaaaaacc
    42541 tcgttatatt cttttgttgt aacaatatct ttttgcaatt tcattccttt aaagatatat
    42601 ggttccccct taataccaac ttgtgagtat ggttttgaga atggtactac gttacttaca
    42661 actggagaac caccagatga agctgttggc atcaataatg aactatctgt cgaccaagct
    42721 tgagctttgg catatttttc atatctcttc tctaggtcag tggtctcaga aacagcatct
    42781 tctaacaatt tcttatattt atccaaacca ggtttagcta caacatcctt atcttttcct
    42841 ttcgtaatgc caaggtgttt catggcagaa ccagattttg gatccataat attcaagtaa
    42901 gacgctggat cttgatagct tggagcccat cctgtactgt tcaaatcata gtctttttga
    42961 gaaggagcaa cattgccgta tttatcattt tccatcaaac catcaataac atttccaata
    43021 acgtctgtcc tcgatgttcg agtcgctata ctgtagccca atgatgctgg atctactgca
    43081 tagacataag aaaatgttgt cggtgcatct gcttctttat cagtttttcc acaagccact
    43141 aaaatagctg acgtgctcag gaccactcct gctgttaaga gccacttttt ctatttcata
    43201 aaaaatctcc tttggtttat tttaatctac ttttacaatc caaccttctg gcgcttcaat
    43261 atcgccaaac tgaatacccg tcaattcatt atataattta cgcgtcacag gacctacttc
    43321 tgtttcacta tagaatacat ggaaatcatc accatgttga atacctccaa ttggagaaat
    43381 aaccgctgct gtaccacagg cacctgcctc tacaaaacgg tcaagattat caattggaac
    43441 atcaccctca ataggagtta atcccaagcg atgttctgcc aaataaagca aggaatactt
    43501 ggtaatagat ggcaagatag atggactcaa tggtgttaca aattcattat cagctgtaat
    43561 tccaaagaaa ttagctgatc cgacttcttc aatctttgta tgagttgatg ggtccagata
    43621 gataacatct gagaaatggc gtgacttggc catttttcct ggtaagagac ttgcagcata
    43681 gtttccacca accttagccg cacctgtacc atttggtgct gcacggtcgt actcatcctg
    43741 aatcaagaag ttggttggga ccaaaccacc tttaaagtaa tttccaactg gcatagcaaa
    43801 gatggtgaaa atgtactctt ctgccggttt taccccgata atatctccga caccaatcaa
    43861 aagagggcga agatataaag ttccacctat tccgtatggt ggtacgtatt cttcattcgc
    43921 acggacaact gctttacaag cttctacaaa catgtctgtc ggaacttgtg gcatcaagag
    43981 acggtcacat gtacgttgca ggcgtttagc attttcatca ggacggaaca gttgaacact
    44041 gccatcctta gtacgataag ctttcaaacc ttcaaatgct tgttgtccat agtgaagact
    44101 tggagaagac tctgaaatat gcaaagttgc atcctctgta agctctcctt gatcccattg
    44161 tccatttttg aaatgagcaa gatagcgata aggtaatttc atataggaaa aaccgaggtt
    44221 ttcccaatca atcgttactg tcatattcca ctccttattc taaaaaccta tttcttatat
    44281 tctacactat ttttctaaaa tagcaagtat attttgtaat tttcagaaaa tttctccaat
    44341 aaaaaccatc ttagaactga ttcttcattt cacttattta tcttcagtaa ctacttcctg
    44401 aagataagcg tcaaaaactt cttcatctga aatcgtgtca gaaatgaagc ttccattgct
    44461 agtgcgttct gacaagttca agtcttgcaa tcggctttca tagattgttc ctttattgga
    44521 ttggacaagc agagtttggt cgttcacatc cacttccgta ctgaagaaat cgccaacaaa
    44581 tccttgctct gcaactgctc ctgccaagaa gacacgatgc ggtttgtttt tcaactcacg
    44641 caagacttgt aatcctcgtt tggcacggct ggttgctaga atttcctcaa tagaaacacg
    44701 tttcaagctt ccacgctggg tcaagaggta gaaggacgaa gtattacaga taaagccaga
    44761 ttggaggaca tcatcttctt tcaaattcat agccttgaca cctgctgcct tagcaccgac
    44821 aaccggaacc tcttcgatat tgaaacgcag ggcataacca ttttgactaa ccaagacaac
    44881 atcatctagt ttaatcggag ccactgctac aatctgatct gtatcgtctt tgagcttagc
    44941 atacttgaca gacttagatc tataggtccg ccatggagtg aattcttttc gctctacccg
    45001 tttgatttga ccaaggcgag tcactgcaaa gtaggttgtc gcatcgtcaa actgatccag
    45061 tacttccaca taaaggattt cttcattcgt ttcaaagttt gtgatggttt ggctcagatg
    45121 ctctccgatg tccttccaac gaatatctgc caactcatgg attggtctgt agatgacatt
    45181 tccaagactt gtgaacatca agaggtgctg ggttgtcttg gcagattgaa caaaaatcaa
    45241 acggtcatca tcacgcttgc caatttcttc caaggtggaa gccgcaaagg aacgtggact
    45301 ggtacgcttg atgtaacctg ccttggtcac gctgacgtag gtatcttcct cagcgataag
    45361 actagctgta tcaatctcaa ttgctttcgc agtgtcttct aaagaactca aacgaggagt
    45421 tgcaaatttc ttcttgacct cacgaagttc tttcttcatg agattgtaca tagtcctttc
    45481 atcaccgata atagccgcca gcatagcaat cttctcacga agctctgctt cttcttcctg
    45541 caagacaacc acatcggtat tggtcaaacg gtacagttgc aaagttacga tagcctcagc
    45601 ctgttcttcc gtaaaatcat agctaacttt gaggttttcc ttggcgtccg ccttattctc
    45661 agaagcacgg ataagagcaa tgacttcatc caaaatcgaa atcacacgaa tcaaaccttc
    45721 gacgatatgg agacgtttct cagccttttc tttgtcaaag cgtgaacgcg ccaaaatcac
    45781 ttctcgacgg tgagcgatgt agctagacag gattggaaca atcccaacct gacgaggtgt
    45841 gaaattgtca atcgccacca tattaaagtt gtagttgatt tgtaggtcgg tgtacttaaa
    45901 taagtagttg agaacaagct cagtattagc gtctttctta agttcgatag cgatacgaag
    45961 accatcacgg tcagactcat cacgaacctc agcaatccca gctaccttgt tattaacacg
    46021 aacatcatcg attttcttga ctagattggc cttattgatt tcataaggaa tctcagtaat
    46081 aacgatttgt tccttaccac cttttagctt ttcaatttca gtcttggaac gaacaaccac
    46141 gcgccctttc ccagtctcat aagctttctt gatttcatca cgaccctgaa taatagcccc
    46201 tgtagggaag tctggtccag gcaagaattc catgagttta tcaatctttg cagttgggtg
    46261 gtcaatcatg taaattgcag catctatgac ctcagctaaa ttatggggag gaatgtctgt
    46321 ggcataacca gccgaaatcc cagtcgaacc attgaccaag aggtttggaa aggctgctgg
    46381 caagaccgtt ggttctttct ccgtatcgtc aaagttccat gcaaaaggaa ctgtattttt
    46441 ctcgatatcc tgaagaaggt aacctgcaat ttcagacaaa cgtgcctcag tataacgcat
    46501 agccgcagga ggatctccgt ccatagaacc gttattaccg tgcatttcaa ctagaatctc
    46561 acgatttttc cagttctgtg acatacgaac catggcatca tagatagaag aatccccgtg
    46621 tgggtggaaa ttccccatga tgttcccgac tgacttggcc gacttacggt agctcttgtc
    46681 aaaagtattg ccatccttat tcatagaata aagaatacgg cgctgaaccg gcttcaaccc
    46741 atcacgaata tctggcaaag cccggtcttg aataatgtac ttggagtagc gaccaaagcg
    46801 ctctcccatg atgtcctcca gggacatgtt ttgaatgtta gacataagat acaaagccca
    46861 taaaatacca agtgaaaata gaaaattctt gaagtaagca aactcacaag agaatttatc
    46921 tttttcacac agtatctagg gcgtgttcaa ctcctttcaa agaatgtaga gtaggttttt
    46981 atgcagtaaa agatatttta cgggaattcc tcccgtgttc agttacgata agtaaccaaa
    47041 ctatcctgtt tgtatttttc aatatgaaaa tctggttttc caaaattagt cttagtttgt
    47101 gtcttatccg ctcccttaag cgcctctttg agataagcac tcatagcaga ttcttcatta
    47161 ataatcctgc aattttttca aaccaagatt ttcaaactgc tttttcacat agtcattcac
    47221 atccgactct aatttccagt ttactaacat attattttct ttcattaaaa cactgtcgct
    47281 tcttctagcg taaacttgac attatcttca atccatttac ggcgtggttc taccttatct
    47341 cccatgagaa cattgacgcg gcgttcggcg cgcgctaaat cttcaattgt gacacggatg
    47401 agggtacgtg tttctgggtt catggttgtt tcccagagct ggtccgcatt catctcacca
    47461 agtcctttgt atcgttggag ggtagcgcct ttaccgaact gtttacggag ttcttctagt
    47521 tctccgtccg tccaagcgta ggccacttct tctttctttc ctttaccttt ggacatcttg
    47581 taaagaggtg ggagggcaat atagacatga cctgcctcga ctagcggacg catgtaacgg
    47641 tagaaaaatg tcaagagcaa ggtctggata tgggcaccgt cggtatccgc atcggtcatg
    47701 ataatgatct tatcatagtt ggcatcttca atagagaagt ctgctccaac acccgcacca
    47761 atggtataaa tcatggtatt gatctcttca tttttgagga tatccgccat cttggccttg
    47821 gctgtattga taaccttacc acgaagaggt agaatagcct ggaacttgcg gtcacgacct
    47881 tgtttggcag aaccaccggc agagtccccc tcaactagat agagttcatt cttagcagga
    47941 ttcttagatt gggctggggt caatttccca gacaacaagc ccttatcttt cttgtttttc
    48001 ttcccatttc ggctctcatc acgcgcctta cgtgctgctt cacgagcatc acgggccttg
    48061 atagccttgc ggatgaggtt agaagctaat tccccatttt ccataaggaa aaaggtcaac
    48121 ttatcagcca ctattccatc cacaactggg cgagctaggg ggcttcctag tttatccttg
    48181 gtctgtcctt caaactgcaa gtgttcttca ggaactaaga tagaaagaac ggccgctagt
    48241 ccctcacgat agtctgaacc ttcaaggttt ttatcttttt ccttgagaag acctgtttta
    48301 cgtgcatagt cattcatgac cttggtaatg gcagacttga gtcctgtctc gtgcgttcca
    48361 ccgtccttgg tgcgaacgtt attgacaaag gatagaatgt tatctgagaa tccgtcattg
    48421 tactggaggg ctacttccac ttgaaaacca ttgtcttccc cttcaaagta aagaactggc
    48481 gtcaagattt ccttatcttc gttgagataa gaaacaaaat cttgtactcc attctcatag
    48541 tggaactcaa tcgcttcatc tgttcgcttg tccgttaaag acaaggtcac atttttcaag
    48601 agaaaggctg attcattaag gcgctctgaa atggtattgt acttgaaatc tgtcgtagaa
    48661 aatatagtcg cgtcaggcat aaaagtaact ttggtgcctg ttttagactt gggtgctgta
    48721 ccgattttct tcaaagtcgt gacaggtttt ccaccatttt cgaaacgttg cttgtaaact
    48781 gcgccatcac gggtaatttc aacttctaac cagctagaaa gggcgttaac aacggaagaa
    48841 cccactccgt gaagtccacc tgatgtctta tagccacctt gaccgaattt ccctccggca
    48901 tgaagaatgg taaagataac ctcaacagtt ggaattccca tagcgtgcat acctgtcggc
    48961 atcccacgtc catggtcttg aaccgttaga ctaccgtctt tattgatggt tacatcgata
    49021 cgatcaccaa acccagacaa ggcttcatcg actgcattat caacgatttc ccaaactagg
    49081 tgatgaagac cagcgccatc ggtcgatcca atatacatcc ctggacgttt tcggaccgca
    49141 tccaaccctt ctagcacctg aatagcatca tcattataat tgttaatatt gatttccttt
    49201 tttgacacaa ggaacctcct attcgttcat ctttactatt ctacaggttt tccaaggatt
    49261 ttgcaaaatt tttctttctc cgatgtgaca attttagcag agattctctg cttttctttc
    49321 ccaattcatg atataatagg agtatgatta caatagtttt attaatccta gcctatctgc
    49381 tgggttcgat tccatctggt ctctggattg gacaagtatt ctttcaaatc aatctacgcg
    49441 agcatggttc tggtaacact ggaacgacca ataccttccg cattttaggt aagaaagctg
    49501 gtatggcaac ctttgtgatt gactttttca aaggaaccct agcaacgctg cttccgatta
    49561 tttttcatct acaaggcgtt tctcctctca tctttggact tttggctgtt atcggccata
    49621 ccttccctat ctttgcagga tttaaaggtg gtaaggctgt cgcaaccagt gctggagtaa
    49681 ttttcggatt tgcgcctatc ttctgtctct accttgcgat tatcttcttt ggagctctct
    49741 atcttggcag tatgatttca ctgtctagtg tcacagcatc gatcgcggct gttatcgggg
    49801 ttctgctctt tccacttttt ggttttatcc tgagtaacta tgactctctc ttcatcgcta
    49861 ttatcttagc acttgctagt ttgattatca ttcgtcataa ggacaatata gctcgtatca
    49921 aaaataaaac tgaaaatttg gtcccttggg gattgaacct aacccatcaa gatcctaaaa
    49981 aataaaacgc cagttctgta ctgcccccca aaagttagac aaataattta tccgaaggat
    50041 ttagttctgt attgcacagg actaagtcct tttagtttta tcttaatttt cttattgttg
    50101 tagtaatcaa tatagtctac aatagcttgt tccaattgct taagcgactg aaatgacttc
    50161 tcataaccat aaaacatctc cgatttcaga atcccaaaga aggactccat catagtgttt
    50221 ctctgtgaat gcctgttcca acattgtttg tacttgttct aagttgggtg aagttgaaag
    50281 attataggcg ataatttcgc tgttaaagcc atctaaaact ggtgataagt aaagcttttg
    50341 agtacttgct ggaatggcaa attctgtcac atctgtgtag cacttttcca ttgttttaga
    50401 gccttcaaat tggccttgaa tgagattctc tgccttcttg ccaacgtctc ctttatgaga
    50461 agaatatttt cgtttctgtc gcattttagc ttgtaaattg agtactttta tcaagccttg
    50521 aactctttta tgatttacca gataaccacg atttcttagt tctaaatgaa cccggcgata
    50581 agtataattt cccttgtgtt cgataaaaat ggattgaatt tcagctttaa gctattggtc
    50641 cttatctggt ttatctagct gtttcaagtg atagtagtag gtccaacgag ctagtttaat
    50701 ggcttctaga agaagatcta acgaaaactc agtcattaat tcttgaacaa tttctgtctt
    50761 tcttctttct ctttttcctc cttcaatcgg agttctctta acttttttag gatggcattc
    50821 tccgctctca ggtactcatt ttctgcttga agacgttcta attctgtcct ctcttcaggt
    50881 ctcgttcttg gcttacgtcc cattttaggt actctccctc ttggtttctc aacaatagta
    50941 tacccgtttt tcctgtattg tgctagccag ttaagaagta tcgtacgact tgggagaccg
    51001 tattcaagag aaactctatc tttagtctag ccttcatgtc agactttatg aatcatttct
    51061 tgttttaaat caggagaata gtaacgattt tttccttttt tgacgaactc tattccgtaa
    51121 cgatcaatca atttaatcat gtacctaaga ttagaattgt ttatcccaaa tttatttgaa
    51181 agcttctcta agctatatcc ttgttttcta agttcataga tctgaacttt atcatcataa
    51241 gttagtttca taataaaaac accccaaaag ttagattttt tctgtctaac ttttgggggg
    51301 cagttcagtc attggactga cgtttttttg tatgcttatt ttgatttgat gtagttgata
    51361 ccatctgctt ttggtgcgac tgcttttcca aagaaggctg ctaagacaag aattgtcaaa
    51421 acataaggtg caatttgaag ataaaccgct ggcactcctt gtaggaacgg caattgagaa
    51481 ccgataacag ccaaactttg tgaaagtcca aagaagagac tagaaagcat agcaccgatt
    51541 ggattccatt tcccaaagat catcgcagca agggcgataa atccaggtcc aacaatagtt
    51601 gtcactgaga agttaactga gattgattgc gcataaatcg ctccgccaat tccacctaga
    51661 aaacctgaaa taataatccc taaatatctc atcttgtaga cgttgattcc caaggtatcc
    51721 gctgcttgag gatgttcacc gacagagcgg agacgaagac caaattgagt cttaaagaga
    51781 ataaaccaag caaggaatga gaaggcaatc gccagataac caagtagact agttgacttg
    51841 aagaagatat caccaatcac tgggatattt gccaagactg ggaaatcaaa gcgtccaaaa
    51901 gtttgactta ggttgtcggt ttgtcctttg ttataaagaa ctttaactaa gaaaacagcc
    51961 aaggcaggcg ccatcaagtt caataccgta ccgctgacaa catggtctgc acggaaatga
    52021 accgtcgctg ctgcgtggat gatagagaaa acactaccaa ccaatcctgc tacaagcaag
    52081 gatagccatg gagttgctgc tccaaattgt tctgcaaatt caaggttaaa gacaactcca
    52141 gaaaaggcac ccataaccat aattccttca aggccaacgt ttaccacacc accacgttca
    52201 gagaaaacac caccgatact tgtaaagatg agaggtgctg agtaaatcag catagaagac
    52261 accaagaggg ggagcaaggt tataatagac atctttactt acctccttta acttgttttt
    52321 tcggtttgac aaagcgttcg ataaggtaat gaacactgac aaagaagata atagacgctg
    52381 ttacaatgct gacaagctca gatggtacct gcgccgcatt cataccagga gccccaactt
    52441 ggagaacgcc aaataggaag gctgcaaaga gtataccaat tggtgagttg gccgcaagca
    52501 aactaaccgc cattccgtta aatccgatag ctaatgacga accttgaaca tagacgttct
    52561 ggaaggttcc caaaccttca acagctccac caagacctgc caaggcacct gaaataatca
    52621 tagataggat aatagtccgc ttggcagaaa taccagcata ttctgaagca tgtggattaa
    52681 gaccaactgc acggatttca aaaccaagag ttgttttctt gagcatgaac caaataactg
    52741 caacggcaat gatggcaaag aaaataccaa tattcatccg tgagttacca gtcaactcag
    52801 ccaaccaagg tgtctgatag gttgcattag ccccaacacg aatggtcgaa tctgtacttt
    52861 gcatgaagtc tttaggaaaa gcatggataa aggcattccc tacatacaag acaatgtagt
    52921 tcatcatgat ggttacaata acctctgacg tccctagata ggccctaaga atacctggaa
    52981 tcgctccgac aatcccacca gcaatcaagg caatcacgat ggttgctaga atcatcaagg
    53041 gacggggcat atctggatgc gacagcgcaa accaaccact gagaatccaa cctgccaaag
    53101 cctgaccagg aagtccgacg ttaaagaaac cagctcgact ggcaaccgca aaaccaagac
    53161 caatcaagac cagaggaccc atagcacgga agatttcgcc aatcccacgc agactgccaa
    53221 aggctgtata gaacaattct tcgtagcccc aaatagcatc ataaccgaag atccacatga
    53281 caatggctcc gagtaaaatt cctagaaata cagaaatcaa gggaaccgaa atttgttgta
    53341 attttttaga catcactctt ctcctttccc aagtttccac cagccatcaa gacaccaagt
    53401 tcttgtttat tggttgtttc tggtgataca ataccttgaa tcttaccatc gtggataacg
    53461 gcaatacggt ctgagacgtt taaaatctca tccaattcaa agctgacaac aaggacagcc
    53521 ttgccattat cacgctcttc aatcaagcgt ttgtggatat actcaatggc accgacatcc
    53581 aacccacgag ttggctggct aacgataagg agatcaggat ctcgattaat ttcacgagca
    53641 ataattgctt tttgttgatt tcctcctgag agtgcagctg caggaactaa ttcactggca
    53701 gcacgaacat caaactcttc catcagcttt ttagcataag aagtaatatt tgaataattc
    53761 aaaattccat ttttactatg tggttcttta tagtaggttt gaagggcaat attttcagat
    53821 atcatcattt ccaaaatcaa gccatcacgg tgacggtctt ctggaacgtg cccaacactt
    53881 agttctgtaa tctgacgtgg gtgcaagcct acaattgaat ctccttttag ctcaatgcta
    53941 ccagattcaa ccttacgaag acctgtaatg gcttgaatca gttcagactg accatttcca
    54001 tcaatccccg caataccaac aatctctcca gcacgaacat ccaaggacag atttttaaca
    54061 gctggaacac cacggttttc attgaccacc aaatctttga tagacaaaac cacttctttt
    54121 ggtttagagg cttgcttctc tgttttaaag gaaacagaac gtcctaccat catttccgcc
    54181 aaatcagcat tggtagcccc tgcaatttca acggtttcaa ttgatttccc acgacggata
    54241 actgtaacac ggtcagaaac tgctcgaatt tcatccaatt tgtgggtaat caagataatt
    54301 gattttcctt ctttgacaag atttttcata atagccatca actcatcaat ttctgatgga
    54361 gtcaaaacag ccgttggttc gtcaaagata aggatatcag ccccccgata aagtgttttt
    54421 aaaatttcta cacgttgttg ggctccaact gagatatctg ctaccttggc agaagggtca
    54481 acagctaagc cataacgttc agaaagagcc ttgatttctt tgctagctcc agcgatatct
    54541 agcacaccat ttttagtcaa ttcactacct aaaatgatgt tttcagccac tgtgaaggct
    54601 tcaaccaaca taaagtgctg gtgaaccatc ccgattccca agctagctgc tttagatggg
    54661 gagtcgagat tgacaacttg accgttgacc gcgatttcac cactagttgg ttcaagaagg
    54721 cctgctaaca tgttcattag cgtggactta ccagccccat tttctcctaa aagtgcatga
    54781 atttcacctt ttcgtaggtg caagttgatt ttgtcgttgg caacaaatcc accaaacacc
    54841 ttggtaatat cacgcatctc aatgacattt tcgtgtgcca tgtgctcttc ctttcagagt
    54901 cttattttat ttcaataaaa cttgctagtt tgtctagtag caagctttac tgagacaaaa
    54961 tgactttgtc tcaactctta aaaaagcggc ccttggccgc ttcctaagaa atgacttcca
    55021 tccattattt ttcaggaact tttacgcttc catcaaggat tttagctttt gcatcttcga
    55081 cagctttttt accttcttct gaaaggtttg ttactgccaa gtcaacccct ttatccttca
    55141 atgagtaaac gatcacttga ccgccaggga attctccttt ttctgccttg ttagaaatat
    55201 cttttacagt tgtaccaact tgtttcaaag tagatacaag aacaaagttt gattctttgc
    55261 catctttaga agtgtattta ccttctgctt cttggtcacg atcaacaccg ataacccaaa
    55321 ctttttcatt ttcaggacgg ctttcgttga gagattttgc ctctgcaaag acacctgcac
    55381 ctgtaccacc agctacttgg taaacaatat ctgcaccggc tgcgtattgt gcggctgcaa
    55441 ttgttttacc tttagccgca tcaccaaatg aaccagcgta gtcaacttgg actttgatag
    55501 atgggtctac tgacgcaaca ccagccttga atcctgcctc aaaacgagag ataacttcag
    55561 attcgatacc acctacaaaa ccaacttgtt ttgtcttagt tgtttttgct gcagccacac
    55621 ctgcaaggta acctgactca ttatcagcga aagttacgct agcaacattt ttttggtctt
    55681 taatcacatc atcaatcaag acatagttca agtcagtgtg ttcttttgct gcttcttcaa
    55741 ctgcattgtg aagggcaaaa ccaacaccaa agattaggtt gtaacttcca gccgcttgtt
    55801 gcaagttgtt agcgtagtca gcttcacttg ttgattggaa gtaagtgaaa ccgttatctt
    55861 ttgaaagatt gtgttcttta ccccagtctt gcaaaccttc ccaagctgat tggttgaatg
    55921 atttgtcatc aacaccacca gtatcagtga cgattgctgc ttttgtcttc acatcagaag
    55981 atgaagctgc gttacgagaa gagcggttac cacatgcagc aagtccaact gctgccactg
    56041 caactaggcc aagacctagc cattgtttct tgttcattac tgaacctcct aaataagatg
    56101 tgcaacgatg ttgcaagtat ggattggttg gccacaagga ccgtgccact cagagagcga
    56161 ctcagactag tttaagtctg taaaagagta tggaagtaat tccccgaccg tcatctcgac
    56221 cgtcgattta tcttttgcga ctaaggtcac ttttaaatct tgttcaaaaa attcgaccat
    56281 tacttggcga caagcaccac atggcgagat cggtttttca gtttgaccat agacaatcaa
    56341 ttctgaaaat tctctttggc cttcagatat agccttaaaa acagctgttc tctcaccgca
    56401 attggtcaaa ggatagctag cattttcgat attcactccc gtgtaaacac ttccgtcttt
    56461 ggctactaaa actgctccga taggaaagtg agaatagggg acataggcat gtttgctggt
    56521 ttcaattgcc agttcaatca actcagtagt cgccatctgc caattctcct tttaaaatag
    56581 ctaccccagc tgacgttccg atacgggtcg cacctgcttc gacaaaggca agagcatctg
    56641 cataagaacg agctccacca gcagccttga ctcccatatc agatccaact gtttcacgca
    56701 ttaatgtaac atctgctatc gtagcaccac cagttgaaaa accagtagat gttttaacaa
    56761 agtcagcccc agctttttgg gccaattggc aaacaacaat tttttcttgg tctgtcagaa
    56821 ggcaagcttc aataatgact ttcactaact tatcaccact tgcttccact actgcgcgaa
    56881 tatctgactc aaccaaggct aaattacctg atttgagagc tccaacattg atcaccatat
    56941 caatctcatc tgcaccattt tggatagctt cttttgtctc aaatgctttc acggctgaag
    57001 ttgttgctcc caaagggaaa cctactactg tgcaaacctt aacatctgtg ccttcaagtc
    57061 cttttttagc atgttcaacc caggtcggat taacgcaaac actggcaaag tcatactctc
    57121 tagcctcaga caacaaacta tcaatttgtt ttttctttgc atcttgtttt aaaagcgtat
    57181 gatctatata tttatttaat ttcatttcgg ttttccctcc atttaggaga tgatttctac
    57241 aatttcacgg atttttttta cttcatcact tattttaaca catttttgga aatctgtaac
    57301 tagttgaggt ggaatttttt catttgtgta tacttttgca acaatttcac ccttttgaac
    57361 ggagtctccc atcttctttt caaaaacaat tcctgtttca tagtccaagg catcagactt
    57421 aactgcacga ccagcaccca gcctcatggc ataaagacca aagtccatag ctggaagagc
    57481 tgaaatgaca cccgtttcct gagcagggat ttccaccaca tgagctacat ttacaggacg
    57541 atagaggtct tccaagtctc caccttgggc ttgcaccatt tcctcaaact tagccagtgc
    57601 ttgaccattc tcaagatgtt ggcgaacttc ttcaacagtt ttgttaacat ttgccaaacc
    57661 aagcataatt tgagccaatt cacaaataaa gtgggtaata tcctgacgtc cttgaccttg
    57721 caaaatctcc aatgcttcaa ggatttccag acgatttcca atcgctcgtc ccaaaggctg
    57781 gctcatatcc gtaatcactg ctactgtctt ccgtccaaca accttaccaa gatctaccat
    57841 agtttgagcc aactcacgcg cctcatcaac cgtcttcatg aaggcaccct caccgacagt
    57901 cacgtctagc aaaatagcat ccgcccctgc cgcgattttc ttgctcatca ccgaactcgc
    57961 aatcaaagga atcgtgtcga cagttgcggt cacatcacga agggcataga gaagcttatc
    58021 tgctttgacc agctggtctg attgcccaat gacagatact ccaatatcct gaacctgacg
    58081 aataaaatcc tcttgactac gttctacttg atagccctta atggactcca atttatcaat
    58141 tgttccgcct gtatggccaa gaccacgacc actcattttt gctacaggca caccgaagct
    58201 agcaacaaga ggagctaaaa tcaaggttac cttatcgccg acaccaccag tagaatgctt
    58261 gtcaactttc acaccatcaa tggctgacag gtcaaactct tgcccagtct taaccatatt
    58321 catcgttaaa tcagaaattt cacgagtcgt cattccttta aaataaacag ccatagcaaa
    58381 ggcagacatc tgataatcag gaacagttcc tgacacatag ccttctacca gccattcaat
    58441 ttcacttgaa gtcagttctt gaccgtctcg ttttttttgt attaaatcaa ctgctctcat
    58501 tctttcacac ttctaaggat atagtatcct ttgtcttttt taaggatttc acaattacca
    58561 aacacatcct ccatcttgga cttagcactt ggagcccctt gttttttctg gatgacgatt
    58621 gtcaaatccc caccagtttc caagaaatct ttacttttct caatgatttc atgaacgact
    58681 tgcttgcccg cacggatagg aggattggaa atgacatgat caaaatgtcc ttcaacttgt
    58741 tcatagatgt tggactggaa aatcgtcgct tttgcattat ttttttcagc atttctccga
    58801 gctaaatcca aggcacgagt gttgatatca accatagtag cctgaactcc ataagcctta
    58861 gctaaggaca aacccaaagg tccgtaacca cagcctacat caaggacagt ttctccttgg
    58921 ttgacctcaa gacacttgag caatagttga cttccaaagt caactatttt cttgctaaaa
    58981 acacccgcat ccgttaaaaa ggtcattttt tgtcccaaca actctactct caactcatga
    59041 atgtcgtgag cagcgtcagg attttctgca taatacattt tactcatgac actattttac
    59101 cataatttga ctcaaattgt aaatcgttta caaattgata ataaaacgaa aaagaccgaa
    59161 gaaagcgagt cacgaagcca ttttcttcaa tctctttcaa cacttataaa taataaacca
    59221 tttagaacta taaatatcac agtccagata aaaacaaaaa gtttatcatc tataatcagg
    59281 cagattatta tttctattgc ttaaccttaa aatactttat tatcaacaaa attcccaaca
    59341 aaatgtttag ataaaagccc aactgatacg tttgtgtcag gatttccaaa cttgtccaaa
    59401 gtcgtatcaa atcttctagt gacatgcgga agaaataacc ctctgtcgca atccatagga
    59461 ctaaaaagca ataactacca gcagcaatcc atttcgccca tcgtttttta gtaagaaagc
    59521 aattaaaaac gaacagataa agacagctgt tacaatagca tgttccatca aaaaagtaaa
    59581 accgtaatag gtttccacaa agcatctacc attatctgca ttggctcctt ttataaaagg
    59641 taaagcaaaa cttaaaataa aacagagttc caatatgtaa cattttaaga ttttcatagt
    59701 acacctccta taagttgtga accaaaaagc cccctttata agcttataaa tcagtagaat
    59761 ctatctccta tttcatcaat aaattgatcg cttatattat atatcattga cttacaacat
    59821 tcaagaaacc gctttatttt tttagctttt tatggtatga tagataaaat acctagggga
    59881 aaacaaatga ccaacgaatt tttacatttt gaaaaaatca gccgccagac ttggcaatct
    59941 ttacatcgaa agacaacacc tcctttgaca gaagaagaat tggaatctat caagagtttt
    60001 aatgaccaaa tcagtctcca agacgttaca gatatctatc tccccttggc tcatctgatt
    60061 cagatttaca agcgaactaa ggaagattta gccttttcaa aaggaatttt cctccaacgt
    60121 gaaagtaaat ctcaaccttt tattattggg gtttctggga gtgttgccgt tggaaaatcc
    60181 acaaccagtc gcctacttca aatcctactg tcccgtacgt ttacagatgc tacggttgag
    60241 ttggttacaa ctgatggttt tctctatccc aatcaaacct tgattgagca ggggatttta
    60301 aatcgtaaag gatttcctga aagctatgat atggaagctc ttctcaactt cttggaccgc
    60361 atcaaaaatg gacaagatgt agatattcct gtctattctc atgaagttta cgacatcgta
    60421 cccgaagaga aacaaagtgt caaagctgct gattttgtaa ttgttgaggg aatcaatgtc
    60481 tttcaaaatc cacaaaacga tcgtctctat atcactgact tctttgactt ttccatctat
    60541 gtagatgctg gagtggatga tattgaaagt tggtatctgg accgtttctt gaaaatgctg
    60601 agtctagccc aaaacgaccc tgatagctac tattatcgtt ttactcagat gccgattggg
    60661 gaagtggaag cctttgccca tcaggtctgg accagtatca atctcacaaa tctacaaaat
    60721 tatattgaac caaccagaaa tcgtgcagaa gtgattcttc ataaaagcaa gaaccatgaa
    60781 atcgatgaaa tttacttaaa aaaataattt tcccttgtca aaacgtaagt tttcatatat
    60841 aatggtatag ttagtaaata tggaggtaag aacattggca aacattaaat cagctatcaa
    60901 acgcgctgaa ttgaacgtta aacaaaacga aaagaactca gctcaaaaat cagctatgcg
    60961 tactgctata aaagctttcg aagcaaaccc atctgaagaa cttttccgtg ctgctagctc
    61021 agctatcgat aaagcagaaa ctaaaggttt gattcacaaa aacaaagcaa gccgcgataa
    61081 agctcgtctt tcagctaaac ttgctaaata agaaacagtc catagaggct gtttttttgt
    61141 ctccaaatag gaaaaggtag aaaatgaaaa tcacaattat cggatattct ggttctggta
    61201 agtcaactct agcagaaaag ttatctaact actactccat tccaaaactg cacatggaca
    61261 cactccaatt tcaacctggt tggcaagaca gtgactgcga atggatgtta accgagataa
    61321 aaaactttct caccaagcat aaagcttggg tcatcgatgg taattattct tggtgctact
    61381 accaagaacg aatgcaagaa gctgaccaaa tcatctttct caattttttg ccattgacct
    61441 gtctctttag agcctttaag cgttatctta aataccgtgg aaaagtcaga gaaagtatgg
    61501 cggcagattg ccctgaacgc tttgagtggg agtttatcag atggattctt tgggatgggc
    61561 gtagcaaaac tcaaaaagaa aattaccaaa aactttgcca agaatattca cataaagtca
    61621 ctatccttcg aaatcagaga gagctagatc aatttctgga taagaaaagg aagtcctaca
    61681 attcataaag ggcttccttt ttggctataa ttattctgca atcaaggttt ctaaaccaac
    61741 cttcatcata tcagtgaagg tattttgacg ttcttctgca gttgtgtctt cgtctggatt
    61801 gaccaagcta tcagagatgg tcatgatagc tagcgcatca acatggtatt gggcagcaag
    61861 atagtaaaga gctgctgctt ccatttccac agccttgact ccccatttac caagctcgat
    61921 attcttttca aagtaatttg agtaaaagac atcagatgac aaaacgttcc caacgtgagt
    61981 agtcatacca agttctttgg cgatatggta ggctttatca agcaaatcaa agctagcaat
    62041 ttgtggaaaa tcgtactgtg gccagtcatt acgaacgatg tttgagttgg ttgcagccgc
    62101 ctgcgccaaa actaattcac gaacatgaac ctcttcattc aaagaacctg cagttcccac
    62161 acgaatcaat ttcttcacac cgtagtctac gattaactca cgcgcataaa tcgaaataga
    62221 tggcattccc atcccagttc ccatgacaga tacacggtga cccttgtaag taccagtgta
    62281 accaaacatg ttacgcactt cgttaaaaca aacagcatca ccaaggaaat tctccgcaat
    62341 aaacttagca cgaagaggat ccccaggaag aagaatttta tcagcaattt caccctgctg
    62401 agcagcaata tggatagaca taatttatga tacaaagagc gagaagaaaa cgactgaaaa
    62461 ttaggaagcc gacgagaaat cctgattttt cagtcagatt atctattttc cgagttttcc
    62521 gctcgtgttc aaatcaaaac acacgctcta cctttcttta ttttatattt tatattgaga
    62581 aagataccaa acccgtcaaa aagcgaaggg aaaataggag ttgggcgcag tgagcgatgc
    62641 tcgctagacc aactatcttt ttcccactgc ttttagggtg ggttcaattc ctttctttct
    62701 taattttgat ttagaggaga gtcgcccgta ttcagttcag cgaatacagt ttacccatcc
    62761 tttcgttttt gtttttagaa aagttttcta ctcgtgttca aattagaaca cgcgctctac
    62821 ctttctgttt atactcttcg aaaatctctt caaaccacgt caacgtcgcc ttggattata
    62881 tatgtgactg acttcgtcag tcttatctac aacctcaaag cagtgctttg agcaacctgc
    62941 ggctagtttc ctagtttgct ctttgatttt cattgagtat taattttgtt ctttcacaga
    63001 gagctacctg agttctattc aagctcaggt agtactttct tataaactag acaaactaac
    63061 tgtcattcta ccatcagatt acaagacatc atcgtcactc accttggaat tcaatgtcgt
    63121 accccaatgg gtaattttac ggtggggttg agctaaaatt ggtctgtttt catagattgt
    63181 ttgccatcta ttccatagta ggcccgtctt tttctcaatc ttaactcgca gatttctcat
    63241 attttctttg attgggaggt tgaggacaaa acctgcagtc tggttgcaac cgtttccttc
    63301 ccaagaatga ctacgaacaa cttggtttcc atctttatct actggaactt cttcccaagt
    63361 tatggagtag cgggcaatgt aagctccact atgttgaatt gtcaatgttt tatctttcac
    63421 aggagtctga ctgattggtt gaactggctt agaaacttgt gtcgccgttt cagcattcgt
    63481 agctataaag cggaaaactt caacttctgc aagactgagg gcattatagc cttctagctc
    63541 aatccgaaca tagcgcactt ttttatggtt aatcgtaatt tgtgctgaca catctttagg
    63601 agatgttata cgttttcact caatttcttt accagaactg tctaaaagaa tgacatcaaa
    63661 gtttgccaat ctatcctggg cagtgtctgt tcggttgtaa atattgattt ggcgaatggt
    63721 ttcttcttta gccaaatcta cttgccacca aggcttagat tggaagtttg tatgagtgac
    63781 agaattgtga ccatagttac catcgacttt gccatccaca gctcttctag catctcctcc
    63841 gaaagctgtc gaactttgag taacctgttt tcctaaggca atattttcca ttggttcagc
    63901 gcttggttga ctagaagatt gaggtagagc ctgtttctta aagaatcgcg ctttatccaa
    63961 tttcggatca cgataaccat gtttatccaa ggtagcttgt ttaccaatat taaagttagg
    64021 aatatcattc attggacttt caaaatagcc acgagaacgg tgtttaaagc gtgaattacc
    64081 tgtaaatgta acaatatcac gattattatg aatcaaggga gtcacaacat tgtcattatc
    64141 aaccacataa tgcttaattt ttccactaac agctaattta cgactttcca aaccaacatc
    64201 tcagaaacca ttcttagcat cccaaacagt tctggaagta atcactttag gagcactgaa
    64261 agttgtcact ttcctcaata catggttata aaaatcagga tatttttggt aatcttcaac
    64321 cgctgcaatc tgagctaggt agcctccaag agaatgacct gtcatataca acttagtaat
    64381 acttatatcc ttggctaatt ccccaacaac cttgcggata tcatccgctt gagctggctc
    64441 tgttatctct acttttgact cttccctttt gttttcaaga acttcacttg cttccggaag
    64501 cgtttgagga gctagtcttg gctcctctct aagaggagtt tctagttttg gagcatcatt
    64561 ttctgactct ttcaattcct ccttagaatc tagcacacct attaccactt cagatgttac
    64621 atcttgcttt acttcattgg ctgaaattcc agctggagct agaaatcaaa gccgactaca
    64681 acagatacaa ctccgatact taatttttta tgccaaagcg cataattcgt tgaccaattt
    64741 tcattatttc ttatctttct tttcgtttat ttacaagcag actcaagcga aatctcattg
    64801 tgctatatat gataagactg agaaattcag aaagtcaatt cattctcatc tctccttatc
    64861 atactagtct gcttggctag gaagctaatg ctagtatcct agaatcttgt ctttcacaat
    64921 gctggctatc agatcagaca cacctattct tccgcttctt tcagttataa gagcaggaag
    64981 aagctcatag tattcctctg tttcttcttt aatacggata ggcagtcaat cctgaaaaga
    65041 cagaggcact ccccctttta aatctttttt cttacaattc agcaagaatc gctttaagca
    65101 agcctttgaa atcaccttta acacgttcag tcacttctac aacttcttcg tgattgagtt
    65161 cttcttggaa accagccgca aagttagtga tacatgaaat tcccagaact ttcaagccag
    65221 agtgggctgc cacgataact tcaggaaccg tagacatacc aactgcatct gctcccagtg
    65281 tcttatagga acgaatttct gctggtgttt cataagtcgg accagtaact ccgatataga
    65341 caccttcatc aatcttgata ttaagttttt tagccacttc atgggcagtg gcacggtatt
    65401 ctggtgtgta ggccctagac atatctggga aacgtgggcc aaagtcatcc aagttttcac
    65461 ccatcaatgg attttgcccc gtcatgttga tatggtctga gatagccatc aaggtaccag
    65521 gaccaaatct gataccgcca gctgcattgg ttacaataac accttcacat ccaagaactt
    65581 tcatcacacg aactgggaaa gtcaccactt ccagaggatt cccttcatag aaatggaaac
    65641 gcccttgaag agccaagacc ttgcgacctg ccagttcacc atataccaat ttaccagcat
    65701 gaccgactac tgttgaacgg ccccagtttg gaatctcagc atagtctact acaactggat
    65761 tttcgatttc ttctgccaat tctccaagtc ctgacccaag gattagaccg aactcagggg
    65821 ctgcaattcc cttttctttc aggaaagtag cagtttcatg gattttgttt aaaaatgtca
    65881 ttgtgtgtct cctttattat ttttttagca tttgaccaat tttgtcaaag gttttagcat
    65941 tacgaatagt aatgtggcgg tagaaaggca ccttcagcaa gtacttctga taggcagtct
    66001 tagaatagga ttcttcagaa aatttccccc agaaaatccc aagttttcca aaataaagca
    66061 cttcatcttt cagctctaaa ctttcaactg tcgcgatgac ttggtccaca tccaaaccct
    66121 cagtgtaaaa gagaaaatct tttcgtgcca agtctctgct ccaccaagct ggtagatttt
    66181 caagttccgc ctcaaagtcc tctagactca gtaaagaaaa gctctgaata aatggataat
    66241 ggactgcaaa gaaagtctct agcttttcaa ccaattgggc tttggaatct atcgaagcaa
    66301 agaaaatatt gccactgttg atgtagctct caaccttttc cagtcccaag tttgtcaatt
    66361 cttgatgaag ctccgccatg acgaccttat tcttactacc aacattgata cctctcacca
    66421 gcaaagcata gcgcgtcatc ttataccaat ttatctaaga aactttcccc aatcatagca
    66481 gtttccacac caaagttatc ggcaacagtc gctgaaatat ctgcaaaatg tcctactgga
    66541 atgagaccat ttcctttaaa ggcagggcta taggccaaca atggaatata ttcccgagtg
    66601 tgatccgttc ctgcatacgt tgggtcattt ccatggtccg cagtaatcaa gagaaggtca
    66661 ttctctctca tagctgcgat aatttcaggt aagcgttcat caaactcatg caagcaatca
    66721 cggtaaccgt gagcattacg acgatggccg taaagggcat caaagtcaac taggtttgtg
    66781 aatgagaatc ctttttcaaa ctcagcaagt cccatagtct tcaatagtgt atcaattcca
    66841 tgactatttg acttgttgtg acccatgtca tggttgatac cagcaccgtt aaagatatcg
    66901 ttgattttac ccacagcata agtatcgata tcagcctcat tcaatttatc caaaacagtt
    66961 ggggaaaatg gagatacagc caagtcacga cggtttgccg tacgagtgaa gttacctggt
    67021 tcacctacat aagggcgagc aatgatgcga ccaagaaggg caggacgctc aagggtaatc
    67081 gaacgagcgt attcacagat acggtacaat tcatccaaag gaataatgtc ttcgtgggca
    67141 gcaatctgca aaacagggtc agctgaagta tagataatca actctccagt ttccatctga
    67201 cgtggtccaa aatcatcgat aacagccgtt cctgaataag gtttgttggc ttcacgaata
    67261 accttgcgtc ctgagaattc ttcaattttt gtcaggattt cttctgggaa tccgttccag
    67321 aaagtatcga aaggctcagt aatgttgagt cccatgattt cccagtgtcc agtcatagta
    67381 tccttaccaa gagatacttc ctctaatttt gttgcatatc cagttggatt gctttcagct
    67441 gctacagtct taagaggagt ttcacgagga atatttccaa gacctatttt agccatgttt
    67501 gggacattca aaccaactgt ttttgaaatg tgtcccagtg tgtcagaagc tccatctgga
    67561 acccctgcat tgacaaagtt attagcatct ggtgctgcac cgattcctac agaatccagt
    67621 accaccaaat gaatacgatt aaatttagac atcttatgcc cccttctatt ttcctttttt
    67681 tgaagttgaa atctgaactc catctcgtcc agcaacgatt accttatcca ccatttggtt
    67741 gaataaacca tgctccacaa caccaacgac atggtccaat tcttgtccaa aagcaattgg
    67801 attttcaatg acatccaagg cgaggtcaat gataaaattc tgcatatccg tcacaaaacg
    67861 ttggccgtct ttttcacgga aacttggttt gtagccagct cgttcaaaat gacgaaagac
    67921 ctgctctgca ccatactgaa ccacttctac tggcaattta aaagcaccta gtttttcgac
    67981 cagcttgctt tcatccacca cccaaatgta ttcttttgat ggtgttgcga ccaccttttc
    68041 catgagaagg gcaccaccac cgcctttgat tccattaaac tgactatcca cttcatccgc
    68101 gccatcaacc gtcacatcga caaagtctac ttggtcaata gacttgagcg ggatattaag
    68161 gccttctgcc tgtttagtgg tcacactaga agttgttaca gctgtaatct gtaatccttc
    68221 ttccttgata cgacgaccga tttcttcgac aaaataatag gcagtcgagc ctgttccaag
    68281 tccaacgacc attccatcgc tcacgaactc agcagccttg atacctgcca ttttcttcag
    68341 attttccacc gatttacctc catcattctc agttcttatt ttactatgaa accgcttttt
    68401 attcaagtaa aaacatcaaa tctacatttt tcatcaatct ttctttaaaa atatgcattt
    68461 tatttttacc aaacgaataa aaatgagttt atcttttatg tatttgattt gttcatctct
    68521 ttccagttac aaaaacaaac tcttaacttt gatacgtcta gtttagcctt aaagcaggcg
    68581 catttcaaga atcatacatt aagagaagga agtagattta tctgtctatt ttaaacaagt
    68641 ttatctttgc ttaccctctc ttgttgacaa ataattttca ttattttggg aagatacctg
    68701 ctgatttccg tcggtaagac cacataattt tcttgagata gttcttgggc tatggctgaa
    68761 tgaagatgag tcgctactgc cacacgctcg tagagactgg cctgtcggaa ttggcctaca
    68821 aatcctgcga tcatcccagc cagagcatct cccattcccc cagtcgcctg ataaggacca
    68881 ccaacctgta actggtaata atcagattgg ccaacttccc aaatacgagt agctgggcct
    68941 ttctccacca aaattgttcc ttgagggaag gaagtcagaa cactagccgt tgcatcttcc
    69001 ttttgctttt caatcgtaat tccagataat ttttcccatt ctttttggtg aggagttagg
    69061 ataagctggc ttgagggaaa tgacaaactt gtcctagcaa gaatggtcaa ggcacctccg
    69121 tctacaatca aaatctgatt ttggcttaaa ttaacaaaga cctgttttac tagattttct
    69181 ccagaagcat cgtctcgtaa accaggcccc agcaagacaa cttctgcctt ctccaattgc
    69241 tcttttaaca attgctggtc ttgaagagaa aaggccatag gctcaggtaa atggctgtgc
    69301 agagccggga tattttccct gtccgttcca acggtcacca atcctgcacc gctttttaca
    69361 gctgctaaag cagccatgat gatggcacct ccataaggat aagtaccacc aagcagcagc
    69421 agacgaccat aatctccttt atgacttgaa cgagaacgtt caataataac tttttctaat
    69481 aagatttgat taatcacttt catccttttt tcctctcact tttattatac aataaaaagg
    69541 agacgcagac ctccttttgt aatcttatat ctaaaattta atattcattt ctgccatttt
    69601 agatatagct atagaaaata cactctatta atcgaatgtt tctcttattt tctatccaat
    69661 gtccgaagtg ctgcttgata agtttgctcc atcagcatgg taatggtcat aggaccgaca
    69721 cctccaggga ctggcgtgat atggctagca agtggtgcaa ctgcctcata atcaacatct
    69781 ccacagagct tcccattttc atctcgattc atcccaacgt caatgacaac cgcacctggt
    69841 ttgacaaagt cagcagtcac aaacttggcg cggccgattg cgactacaag aatatctgct
    69901 ttagcagcca ccttggcaag attatgagtt cgtgagtggg ccaaggttac tgtcgcattt
    69961 ttagccaaaa gaagctgagc cataggtttt ccaacgatat ttgaacgacc gattacgacc
    70021 gcatttttac cttccaagtc aatcccatat tcatgaaaca tttccataat tcctgcaggt
    70081 gtcgagggaa tcatgactgg atgtccagac caaagacgtc ccatgtttag gggatggaaa
    70141 ccatccacat ccttttctgg gtcaatggct aataaaaccg cctcttcatc gatatgtttt
    70201 ggtaatggca actggaccaa aatcccatgc caagctggat cctgattata tttagcaatc
    70261 aggtctaaca attcctcttg agtaatggtc tctggaactc gcactacttc gctacgggaa
    70321 ccagccgcaa gagctgacct ctccttgttg cgaacgtaga cttggctggc tggattatcc
    70381 ccaaccaaaa tcactaccaa accaggcact agagctgttt cttcctttaa ttttgcagtc
    70441 ttttcagcca actgcccctg caatttggcc gctaaagctt tcccatcaat aatctgtgtc
    70501 atatcacttc tcttttcttt caaatatctt ccattatacc aaaaactgct agtgccctct
    70561 aacacttctt tcctaggtta tcctatagtt tcaaactata agaaaaagct ctggttgaac
    70621 ttttcactaa tcttgtcttg aaattttaaa atagattata aaaccttact caagaaatct
    70681 ttagtccgtt gttcttgggt ttgttcaaaa atctgctcag gtgtcccatc ttcaacaacc
    70741 acaccgtctg ccataaagat aacacgatct gccacctcac gggcaaatcc catctcatgt
    70801 gttacgataa ccatagtcat ccctgacttg gcaaggtctt gcataacagc caatacctca
    70861 cctaccattt caggatccaa ggctgaagtt ggttcgtcaa agagcaaaac atctggttcc
    70921 atagccaacc cacgcgcgat ggcaatccgt tgttgttgcc cacccgacag actctgtgga
    70981 taagcgtctg ccttatctgg caaaccaact ttttccaaaa gctcttgggc tctcttctca
    71041 gcaacttccc tgctttcacc tttagtcttg ataggtgaca aggtaatatt ttccatcaca
    71101 gtcatattag gaaagaggtt aaattgttgg aaaaccatgc ccatcttctc acgcatggca
    71161 aacaggtcat tcttcttgtc cgtaatatcg actccctcaa agataacctt ccccttggtt
    71221 gcttcctcca acaaattcat agagcgaagc aaggtagatt tcccactccc tgaaggaccg
    71281 atgataacga caacttctcc tcttttaatc tcgaggttga tgcccttcaa tacttcattc
    71341 tttccaaaag atttatgtaa attttcaatt tttatcaagg tttctgtcat tatttcttat
    71401 ctccttgtcc catatgtttt tcaaaagctt tcaaggctac tgtcagaata gaggtcataa
    71461 tcaagtagta aaatgctgca aataaaagtg gtgttaaagg tagataggtt gttgtagaaa
    71521 ctgttgtagc cccattccac aactccatga ccccaatagc tgataagagg gagctgtcct
    71581 tgataatggt gataaattcg ttccccaatg ctggcaagat atttttgact gcttgtggca
    71641 aaatcacata acgcatcgca tttttaggac gaatccctag cgaataagcc gcctctagct
    71701 gaccttttgg aaccgcattg attccggcac gaacaatctc cgaaacataa gcaccactat
    71761 tcatagagat aatcaaaatc cctggaatca gacgcgaaaa atcaacacct aaaattccaa
    71821 tctgaatagt cggagcattg atatgcataa gagcaaaggc aatcataatt tgaaccatca
    71881 tcggtgtccc acggaaaatc caaacgtaca agttggccaa ccaaacaagc ggtttaaact
    71941 ttgaacgttg cccaaaagcc aagacaacac ccaaaatagt tcccaaaaag ataacacaga
    72001 tagaaataag aatcgtcaca acagccccat agttaaaata aggtaaatac ttaggtaaaa
    72061 aagaaaaatt catagtcaca ctgctttcta aaatagaata ctgtatgatt ataacatgtt
    72121 ttgaattaaa atttaaattt tttatccaat ttatttaaaa atctttaaac tagcagaatt
    72181 agcgagaaat cttagttttt tctagtcaag ttggcctcct ttatggtaaa atagtaacga
    72241 taagaaatga aggagaatca aaatggaatc acatttggtt agaatcatca accgccttga
    72301 agcaatggca aacgatggcg gaaatttaaa acgtaatttt gaacgcgaag gagttgttgt
    72361 tgcagaagtt gcgtacagcc acgacgaaga aaacggccca atctttaccc ttcgtgacgt
    72421 agaagatcgc gaaacgtata cgtttgatag cattgactta atcgcaatgg aaatttacga
    72481 acttctctac taatctaaaa caagctggga ttgtccctgc atgtctaagt aaaatccttt
    72541 ttgtctcaca aataggattt ttttatagtc caaattcaca aaaattttca ttgtaacaac
    72601 ttctcaaagc ttcaatcttt ttacttgctt tacaccccaa tcctgttata atgagagtat
    72661 agaatttgac tatttttgac ctttaaacaa gtcaggctaa agaaagaaat gaggtagatg
    72721 tatgctttgt caaaactgta aaattaacga ctcaacaatt catctttaca ccaatctcaa
    72781 tggaaaacaa aaacaaattg acctctgtca aaactgctat aagattatca aaacagatcc
    72841 taacaatagc ctcttcaaag gtatgacgga tctgaacaat cgtgacttcg atccctttgg
    72901 tgatttcttc aatgatctaa acaatttcag accttctagc aatactcctc ctattccccc
    72961 aacccaatca ggtggaggtt acggtggaaa cggcggttat ggttcccaaa atcgtggatc
    73021 tgctcaaact ccgccaccta gccaagaaaa aggcctgctg gaagaatttg gtattaatgt
    73081 aactgaaatt gcccgtcgtg gagacattga ccccgttatt gggcgcgacg atgagattat
    73141 ccgtgtcatc gagattctca atcgtagaac caagaataat cctgtcctta tcggtgaacc
    73201 tggtgtcgga aaaacggccg ttgtcgaagg tctagctcag aaaattgtcg atggcgatgt
    73261 gccacataaa ctccaaggta aacaagtcat ccgtctggat gtggttagct tagttcaagg
    73321 aacggggatt cgaggacaat ttgaagaacg catgcaaaaa ctcatggaag aaattcgcaa
    73381 acgtgaagac atcatcctct ttatcgatga aatccatgaa attgttggtg ctggttctgc
    73441 gagtgatggt aatatggacg caggaaatat cctcaagcca gcccttgctc gtggagaact
    73501 gcaactagtc ggtgctacta ccctcaatga ataccgtatc attgaaaagg atgctgccct
    73561 cgagcgtcgt atgcagcctg ttaaagtcga tgaaccaacg gtggacgaaa caatcactat
    73621 tctcaaaggg attcaaaaga aatacgaaga ttaccaccac gttcaatata cagatgctgc
    73681 gattgaagca gctgcaactc tttccaatcg ctacatccaa gatcgcttct tgcctgacaa
    73741 ggccattgac ctcctagatg aagctggttc taagatgaac ttgaccttga attttgtgga
    73801 tcctaaagta attgatcagc gcttgattga ggctgaaaat ctcaagtctc aagctacacg
    73861 agaagaagat tttgagaagg cggcctactt ccgcgaccag attgccaagt ataaggaaat
    73921 gcaaaagaaa aagatcacag accaggatac tcctatcatc agcgagaaaa ctattgagca
    73981 cattatcgag cagaaaacca atatccctgt tggtgatttg aaagagaaag aacaatctca
    74041 actcatccat ctagccgaag atctcaagtc tcatgttatt ggccaagatg atgcagtcga
    74101 taagattgcc aaggctattc gccgtaatcg tgtcggactt ggtaccccta accgcccaat
    74161 cggaagcttc ctcttcgttg ggccaactgg tgtcggtaag acagaacttt ccaaacaact
    74221 ggctatcgaa ctttttggtt ctgctgatag tatgattcgc tttgatatga gtgaatacat
    74281 ggaaaaacat agtgtggcta agttggtcgg cgctcctcca ggttatgttg gctatgatga
    74341 ggctggtcaa ttaactgaaa aagttcgcca caatccatat tctctcatcc ttctcgatga
    74401 agtggaaaaa gctcacccag atgttatgca catgtttctt caagtcttgg acgatggtcg
    74461 tttgacagac gggcaaggac gcaccgttag cttcaaggat gccatcatta tcatgacctc
    74521 aaatgcaggt acaggaaaga ccgaagctag cgttggattt ggtgctgcta gagaaggacg
    74581 taccaattct gtcctcggtg aactcggtaa cttctttagc ccagagttta tgaaccgttt
    74641 tgatggcatt atcgaattta aggctctcag caaggataac ctccttcaga ttgtcgagct
    74701 catgctagca gatgttaaca agcgcctctc tagcaacaac attcgtttgg atgtaactga
    74761 caaggtcaag gaaaagttgg ttgacctagg ttatgatcca aaaatgggag cacgcccact
    74821 tcgtcggact attcaagact atattgagga cacaatcact gactactacc ttgaaaatcc
    74881 aagcgaaaaa gatctcaaag cagttatgac tagcaaggga aacattcaga ttaaatctgc
    74941 caaaaaagct gaagttaaaa gttctgaaaa agaaaaataa atcctataga aaaggagtag
    75001 aaaatgaaat ttttctgctt ctttttttac taaaataact gtaatttctt gacagcttgc
    75061 cctttgtcca ttatgatata tagtagactg aatctgaaat agtacgaaac aattgctaaa
    75121 acatttatag aaattaattt tactttccca atcgatttgt tctcatctta tttcaatctg
    75181 ctatagtcaa ttgaaacaag agcaggacaa aagagcctcg taaaaggtat tgcaacaact
    75241 tggtaatacc tttttgaggt gctttttgat atgagcccat gttttctcaa taggattgta
    75301 ctcaggtgag tagggaggaa gaggtaaaag tttatgccca aactcctcgc ataaaagttc
    75361 taacttaccc attctatgga atcttgcatt atccataata ataaccgatg gtgtggttaa
    75421 tgttggtaag agaaacttct gaaaccaagc ttcaaaaaag tcgctcgtca tcatctcttc
    75481 gt
//
LOCUS       DBEJAU010000003        73671 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC323 isolate 683620
            SAMN38261939-rid24807223.denovo.003, whole genome shotgun sequence.
ACCESSION   DBEJAU010000003 DBEJAU010000000
VERSION     DBEJAU010000003.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261939
            Sequence Read Archive: SRR26833919
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 73671)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 73671)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576303.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576303.1
            Genome Coverage       :: 154x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/19/2025 01:05:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,121
            CDSs (total)                      :: 2,078
            Genes (coding)                    :: 1,943
            CDSs (with protein)               :: 1,943
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 36
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 72 of 135
            Pseudo Genes (incomplete)         :: 63 of 135
            Pseudo Genes (internal stop)      :: 51 of 135
            Pseudo Genes (multiple problems)  :: 46 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..73671
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261939-rid24807223.denovo.003"
                     /strain="GPSC323"
                     /isolate="683620"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            complement(34..228)
                     /locus_tag="ACL29Z_000226"
     CDS             complement(34..228)
                     /locus_tag="ACL29Z_000226"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0068600.1"
                     /translation="MKIKEQTRKLAAGCSKHRFEVVDRTDEVSSKHCFEVVDRTDEVS
                     NHTYGKVKLTWFEESFEEYK"
     gene            299..955
                     /locus_tag="ACL29Z_000227"
     CDS             299..955
                     /locus_tag="ACL29Z_000227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006155086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_process: GO:0006865 - amino acid transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="AzlC family ABC transporter permease"
                     /protein_id="HGR0068601.1"
                     /translation="MPTALGYVSIGLACGTIGAPYVTPVEMGLMSLFVYAGSAQFAML
                     ALIVVQAPVAAIAMTVFLINLRLFLLSLHASTYFRHTSLWYNIGMSSILTDETYGVLM
                     GELAHTDKVNPMWMHGNNLNSYVAWFVGTVVGTALGGLLPNPEIFGLDFALVGMFIGI
                     FASQFQIMQRRIPVRNLLIILAVVAVSFFLLLTVVSQSLAVLFATLLGCSMGVVLDGQ
                     "
     gene            945..1268
                     /locus_tag="ACL29Z_000228"
     CDS             945..1268
                     /locus_tag="ACL29Z_000228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000253911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AzlD domain-containing protein"
                     /protein_id="HGR0068602.1"
                     /translation="MVSKYLLLAVIFSGLVTWILRMIPFILVKYKGLPAIVERFLKFL
                     PVSIIFALILSSVVTGKVGSLPQIKWLDFLAVFPTAWVAFRYRNLVGTVLFGVVLIAI
                     LRLVF"
     gene            1372..2202
                     /locus_tag="ACL29Z_000229"
     CDS             1372..2202
                     /locus_tag="ACL29Z_000229"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter substrate-binding
                     protein"
                     /protein_id="HGR0068603.1"
                     /translation="MKKIVKYSSLAALALVAAGVLAACSGGAKKEGEAASKKEIIVAT
                     NGSPKPFIYEENGELTGYEIEVVRAIFKDSDKYDVKFEKTEWSGVFAGLDADRYNMAV
                     NNLSYTKERAEKYLYAAPIAQNPNVLVVKKDDSSIKSLDDIGGKSTEVVQATTSAKQL
                     EAYNAEHTDNPTILNYTKADFQQIMVRLSDGQFDYKIFDKIGVETVIKNQGLDNLKVI
                     ELPSDQQPYVYPLLAQGQDELKSFVDKRIKELYKDGTLEKLSKQFFGDTYLPAEADIK
                     "
     gene            2356..3210
                     /locus_tag="ACL29Z_000230"
     CDS             2356..3210
                     /locus_tag="ACL29Z_000230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000694494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MetQ/NlpA family ABC transporter
                     substrate-binding protein"
                     /protein_id="HGR0068604.1"
                     /translation="MKIKKWLGLAALATVAGLALAACGNSEKKADNATTIKIATVNRS
                     GSEEKRWDKIQELVKKDGITLEFTEFTDYSQPNKATADGEVDLNAFQHYNFLNNWNKE
                     NGKDLVAIGDTYISPIRLYSGLNGSANKYTKVEDIPANGEIAVPNDATNESRALYLLQ
                     SAGLIKLGVSGTALATVANIKENPKNLKITELDASQTARSLSSVDAAVVNNTFVTEAK
                     LDYKKALFKEQADENSKQWYNIIVAKKDWETSPKADAIKKVIAAYHTDDVKKVIEETS
                     DGLDQPVW"
     gene            3310..4683
                     /locus_tag="ACL29Z_000231"
     CDS             3310..4683
                     /locus_tag="ACL29Z_000231"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="M20/M25/M40 family metallo-hydrolase"
                     /protein_id="HGR0068605.1"
                     /translation="MVFPSEQEQIEKFEKDHVVQHYFEVLRTLISKKSVFAQQVGLKE
                     VANYLGEIFKRVGAEVEIDESYTAPFVMAHFKSSRPDAKTLIFYNHYDTVPADGDQVW
                     TEAPFTLSVRNGFMYGRGVDDDKGHITARLSALRKYMQHHDDLPVNISFIMEGAEESA
                     STDLDKYLEKHADKLRGADLLVWEQGTKNALEQLEISGGNKGIVTFDVKVKSADVDIH
                     SSYGGVVESAPWYLLQALQSLRAADGRILVEGLYEEVQEPNEREMALLETYGQRNPEE
                     VSRIYGLELPLLQEERMAFLKRFFFEPALNIEGIQSGYQGQGVKTILPAEASAKLEVR
                     LVPGLEPHDVLEKIRKQLDKNGFDKVELYYTLGEMSYRSDMSAPAILNVIELAKKFYP
                     QGVSVLPTTAGTGPMHTVFDALEVPMVAFGLGNANSRDHGGDENVRIADYYTHIELVE
                     ELIRSYE"
     gene            4676..5737
                     /locus_tag="ACL29Z_000232"
     CDS             4676..5737
                     /locus_tag="ACL29Z_000232"
                     /EC_number="7.4.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000085652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0033232 - ABC-type D-methionine
                     transporter activity [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0048473 - D-methionine transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="methionine ABC transporter ATP-binding protein"
                     /protein_id="HGR0068606.1"
                     /translation="MSRDIIKLDQIDVTFHQKKRTITAVKDVTIHIQEGDIYGIVGYS
                     GAGKSTLVRVINLLQKPSAGKITIDDDVIFDGKVTLTAEQLRRKRQDIGMIFQHFNLM
                     SQKTAEENVAFALKHSGLSKEEKKAKVAKLLDLVGLADRAENYPSQLSGGQKQRVAIA
                     RALANDPKILISDESTSALDPKTTKQILALLQDLNQKLGLTVVLITHEMQIVKDIANR
                     VAVMQDGHLIEEGSVLEIFSNPKQPLTQDFISTATGIDEAMVKIEKQEIVEHLSENSL
                     LVQLKYAGASTDEPLLNELYKHYQVMANILYGNIEILDGTPVGELVVVLSGEKAALAG
                     AQEAIRQAGVQLKVLKGGQ"
     gene            5739..6431
                     /locus_tag="ACL29Z_000233"
     CDS             5739..6431
                     /locus_tag="ACL29Z_000233"
                     /EC_number="7.4.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0033232 - ABC-type D-methionine
                     transporter activity [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0048473 - D-methionine transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="methionine ABC transporter permease"
                     /protein_id="HGR0068607.1"
                     /translation="MESLIQTYLPNVYKMGWAGQAGWGTAIYLTLYMTVLSFIIGGFL
                     GLVAGLFLVLTAPGGVLENKVVFWILDKITSIFRAVPFIILLAILSPLSHLIVKTSIG
                     PNAALVPLSFAVFAFFARQVQVVLAELDGGVIEAAQASGATFWDIVGVYLSEGLPDLI
                     RVTTVTLISLVGETAMAGAVGAGGIGNVAIAYGFNRYNHDVTILATIIIILIIFAIQF
                     LGDFLTKKLSHK"
     gene            complement(6461..7030)
                     /locus_tag="ACL29Z_000234"
     CDS             complement(6461..7030)
                     /locus_tag="ACL29Z_000234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000748387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MptD family putative ECF transporter S
                     component"
                     /protein_id="HGR0068608.1"
                     /translation="MKKSILTTLLFAVLYFLCMGIGVLLGNLFDQTGNMFYAPAFTAL
                     VGGSVYMILVAKVPRFGAITTIGLVIALFFLGTKHGAGSFLPGIICGLLADGVAHLGK
                     YKDKTKNFLSFIIFAFSTTGPILLMWIAPKAYMATLLARGKSQEYIDRIMVAPNPGTV
                     LLFIASIVIGALVGALIGQALSKKFAQKI"
     gene            7165..7779
                     /locus_tag="ACL29Z_000235"
     CDS             7165..7779
                     /locus_tag="ACL29Z_000235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000532354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YesL family protein"
                     /protein_id="HGR0068609.1"
                     /translation="MGRFLDFVFNRFFLGMIATAFFWLLTLAGGIILGLAPASATLMS
                     LYAEHGYSFREYSLKEAWSLYKQNFISSNLIFYSFLGVGLVLTYGLYLLVQLPHQTIV
                     HLIATLLNVLVVALIFLAYTVSLKLQVYFALSYRNSLKLSLIGIFMSLAAVAKVLLGT
                     VLLVAIGYYMPALLFFVGIGMWHFFISDMLEPVYEIIHEKLATK"
     gene            7757..9427
                     /locus_tag="ACL29Z_000236"
     CDS             7757..9427
                     /locus_tag="ACL29Z_000236"
                     /EC_number="2.7.13.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000800582.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA];
                     GO_function: GO:0004673 - protein histidine kinase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0007165 - signal transduction [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HGR0068610.1"
                     /translation="MKNWRQNRMKQFWLHTLLRTYSSVMIIIIASFAILLSYADWDSR
                     EKEAQRVAQRVTARTVSEIEYYHRESTQIAQALVENQARIEGIYKYFSLSMPDYFYWQ
                     LERKASPYISVSLYENVDDLYVRNDFVTGVAIAFQDYKEVYVSTKDKRSGEKIRAEDF
                     KPAGNSFAIPVSDPVSDQDLGVIYISLDPAVLYHAIDNTRGHTPMAVTVTSPFDTEIF
                     HIGETVDRESENWLVGLTSHGYQVQVAVPKNFVLQGTVTSSALIVGLSLLFIVILYLT
                     LRQTFANYQKQVVDLVESIQVIAQGEEGRRIDISEKDQELLLIAETTNDMLDRLEKNI
                     HDIYQLELSQKDANMRALQAQINPHFMYNTLEFLRMYAVMQSQDELADIIYEFSSLLR
                     NNISDERETLLKQELEFCRKYSYLCMVRYPKSIAYGFKIDPELENMKIPKFTLQPLVE
                     NYFAHGVDHRRTDNVISIKALKQDGFVEILVVDNGRGMSAEKLANIREKLSQKYFEHQ
                     ASYSDQRQSIGIVNVHERFVLYFGDRYAITIESAEQAGVQYRITIQDE"
     gene            9439..10725
                     /locus_tag="ACL29Z_000237"
     CDS             9439..10725
                     /locus_tag="ACL29Z_000237"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000278884.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HGR0068611.1"
                     /translation="MYKVLLVDDEYMVTEGLKRLIPFDKWDMEVVATASHADEALEYV
                     QENPVDVIISDVNMPDKTGLDMIREMKEFLPDAAYILLSGYQEFDYVKRAMNLSVVDY
                     LVKPVDKVELGNLLEKIAGQLGERGKKSQTLSQELDEAGFVSYLGDKENWWIGLSKEK
                     QGSFTIPYYVLGQDWQIFISDQPLDGLVVTPFEAPYQEHFERWKLNAEKTLFYGSVNL
                     QQSESLFAYYEPIYRVIIQGNLNQIVEELNLLEKVVLENTPRVPITKQLFIQFVMDVF
                     HLFEHLKADDLTDIVKTIHAIQSFDELVPYIKETLSSFFGQYRMNENVVSVLEVIGRD
                     YQKELSLKDISKALFINPVYLGQLIKRETDSTFAELLNKQRIKAAQQLLLSTSDSIED
                     ICYAVGYSNLGYFYKVFRKLCGKSPKAYRKQVETIL"
     gene            10777..11310
                     /locus_tag="ACL29Z_000238"
     CDS             10777..11310
                     /locus_tag="ACL29Z_000238"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399110.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HGR0068612.1"
                     /translation="MKKKPIYLWVLLILSALISVPSLFGIVSPLPSKEALRAAQKQVA
                     GVNAQQLEDQLNYTYRVAEASHSIFNVALIVLSTILVVVAIVFLVRKNLQYANYTYVG
                     YVLLAIIGSIYGYVGLQDAVQLVQDESMRLTVSIGSKAVSIFYIVINVLFLALVFYKM
                     WRQQKALAEEEETEELA"
     gene            11388..11858
                     /gene="nrdI"
                     /locus_tag="ACL29Z_000239"
     CDS             11388..11858
                     /gene="nrdI"
                     /locus_tag="ACL29Z_000239"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000849618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0010181 - FMN binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="class Ib ribonucleoside-diphosphate reductase
                     assembly flavoprotein NrdI"
                     /protein_id="HGR0068613.1"
                     /translation="MKTISLVYISLSGNTESFVTRLKDYLLSQYKRIEVQKIHIKDLV
                     KEGKNFYEMDHPYVAFLPTYLEGGNGVDNGDVEILTTPVGDFIAYGNNASKCFGVVGS
                     GNRNFNNQYCLTAKQYSQRFGFPVLADFEMRGMLEDIKHVAAIIADLYELEKEN"
     gene            complement(12151..13413)
                     /locus_tag="ACL29Z_000240"
     CDS             complement(12151..13413)
                     /locus_tag="ACL29Z_000240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000075801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_function: GO:0046873 - metal ion transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0030001 - metal ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NRAMP family divalent metal transporter"
                     /protein_id="HGR0068614.1"
                     /translation="MSQAISLNQSTWASKLKAMGPGILMATAAVGGSHIVSSTQAGGS
                     YGWSLLLLVILANVFKYPFFRFGAEYTADTGKTLVEGYAEKGKLYLWIFFILNVFSAM
                     VNTAGVAILCSAIIASAFPMIGLSITQWSLILVAIIWAMLLFGGYKLLDGMVKWIMSA
                     LTIATVLAVIIAAVKHPEYSSDFVEKTPWQMAALPFIVSLLGWMPAPIEISAINSLWS
                     AEKRKTVNFNTEDALFDFNTGYIGTAILAVFFVALGALIQYPTGQAVEAASAKYISQF
                     VGMYASVLGEWSRYLITFIAFLCIFGTVITVIDGYSRVNQESLRLLISQKEDNRKSLN
                     IWMTITAIIGIVIIKFFAGQVSTMLRFAMIGSFLTTPFFALLNYALVTRENKNLPSWL
                     KHLAIAGLIFLFGFAIFFIYALAIGKAG"
     gene            complement(13723..14181)
                     /locus_tag="ACL29Z_000241"
     CDS             complement(13723..14181)
                     /locus_tag="ACL29Z_000241"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3021 domain-containing protein"
                     /protein_id="HGR0068615.1"
                     /translation="MKKQVFHDAAAGVLIGLILSILFSLIYAPNTYAPLNPYSLIGQV
                     MDQHQVHGALVLLYCTLIWAAIGMLFNFGNRLFSRDWSMLRATLTHFFLMLAGFVPLA
                     TLAGWFPFHWIFYLQLIIEFAIVYLIIWAILYKREAKKVDHINQLLEHRK"
     gene            complement(14178..14618)
                     /locus_tag="ACL29Z_000242"
     CDS             complement(14178..14618)
                     /locus_tag="ACL29Z_000242"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000861967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LytTR family DNA-binding domain-containing
                     protein"
                     /protein_id="HGR0068616.1"
                     /translation="MKVELQISETYEEEKLIVQAPQETEKVQKVIEFAENLDQREKIK
                     GKIDDQVYLVEIGKIQRFYIENRKVLAETASQTYSIDLRLYQVLKLLPTNFIQISQSE
                     IINIDSISHLKLTPNGLVEIFLKNESFTYSSRRYLKTIKEKLEL"
     gene            14974..16923
                     /gene="mutL"
                     /locus_tag="ACL29Z_000243"
     CDS             14974..16923
                     /gene="mutL"
                     /locus_tag="ACL29Z_000243"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004250478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0032300 - mismatch repair complex
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0030983 - mismatched DNA binding [Evidence
                     IEA];
                     GO_process: GO:0006298 - mismatch repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA mismatch repair endonuclease MutL"
                     /protein_id="HGR0068617.1"
                     /translation="MSHIIELPEMLANQIAAGEVIERPASVVKELVENAIDAGSSQII
                     IEIEEAGLKKVQITDNGHGIAHDEVELALRRHATSKIKNQADLFRIRTLGFRGEALPS
                     IASVSVLTLLTAVDGASHGTKLVARGGEVEEVIPATSPVGTKVCVEDLFFNTPARLKY
                     MKSQQAELSHIIDIVNRLGLAHPEISFSLISDGKEMTRTAGTGQLRQAIAGIYGLVSA
                     KKMIEIENSDLDFEISGFVSLPELTRANRNYISLFINGRYIKNFLLNRAILDGFGSKL
                     MVGRFPLAVIHIHIDPYLADVNVHPTKQEVRISKEKELMTLVSEAIANSLKEQTLIPD
                     ALENLAKSTVRNREKVEQTILPLKENTLYYEKTEPSRPSQTEVADYQVELTDEGQDLT
                     LFAKETLDRLTKPAKLHFAERKPANYDQLDHPELDLASIDKAYDKLEREEASSFPELE
                     FFGQMHGTYLFAQGRDGLYIIDQHAAQERVKYEEYRESIGNVDQSQQQLLVPYIFEFP
                     ADDALRLKERMPLLEEVGVFLAEYGENQFILREHPIWMAEEEIESGIYEMCDMLLLTK
                     EVSIKKYRAELAIMMSCKRSIKANHRIDDHSARQLLYQLSQCDNPYNCPHGRPVLVHF
                     TKSDMEKMFRRIQENHTSLRELGKY"
     gene            complement(17248..17715)
                     /gene="ribE"
                     /locus_tag="ACL29Z_000244"
     CDS             complement(17248..17715)
                     /gene="ribE"
                     /locus_tag="ACL29Z_000244"
                     /EC_number="2.5.1.78"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001099498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009349 - riboflavin synthase complex
                     [Evidence IEA];
                     GO_function: GO:0000906 - 6,7-dimethyl-8-ribityllumazine
                     synthase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="6,7-dimethyl-8-ribityllumazine synthase"
                     /protein_id="HGR0068618.1"
                     /translation="MNTYEGNLVANNIKIGIVVARFNEFITSKLLSGALDNLKRENVN
                     EKDIEVAWVPGAFEIPLIASKMAKSKKYDAIICLGAVIRGNTSHYDYVCSEVSKGIAQ
                     ISLNSEIPVMFGVLTTDTIEQAIERAGTKAGNKGSECAQGAIEMVNLIRTLDA"
     gene            complement(17716..18921)
                     /locus_tag="ACL29Z_000245"
     CDS             complement(17716..18921)
                     /locus_tag="ACL29Z_000245"
                     /EC_number="3.5.4.25"
                     /EC_number="4.1.99.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001842537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003935 - GTP cyclohydrolase II activity
                     [Evidence IEA];
                     GO_function: GO:0008686 -
                     3,4-dihydroxy-2-butanone-4-phosphate synthase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional
                     3,4-dihydroxy-2-butanone-4-phosphate synthase/GTP
                     cyclohydrolase II"
                     /protein_id="HGR0068619.1"
                     /translation="MEYRKIQEALEALQKGRLVLVIDDKDRENEGDLICSAQAATTEN
                     VNFMATYAKGLICMPMSESLANQLMLSPMVENNTDNHKTAFTVSIDYKETTTGISAEE
                     RGLTARMCVAEDITPSDFRRPGHMFPLIAKKGGVLERNGHTEATVDLLKLAGLKECGL
                     CCEIMNHDGKMMRTDDLIQFSKKHNIPLITIKELQEYRKVYDQLVERVSTVNMPTRYG
                     NFKAISYIDKLNGEHHLALIMGNIEDEANVLCRVHSECLTGDVLGSLRCDCGQQFDKA
                     MKMIVENGSGVLLYLRQEGRGIGLINKLKAYHLQDQGMDTLDANLALGFEGDLREYHI
                     GAQMLKDLGLQSLHLLTNNPDKVEQLEKYGITISSRISIEIEANPYDSFYLETKKNRM
                     GHILNMEEK"
     gene            complement(18941..19576)
                     /gene="ribE"
                     /locus_tag="ACL29Z_000246"
     CDS             complement(18941..19576)
                     /gene="ribE"
                     /locus_tag="ACL29Z_000246"
                     /EC_number="2.5.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000493842.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004746 - riboflavin synthase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="riboflavin synthase"
                     /protein_id="HGR0068620.1"
                     /translation="MFTGIIEEIGKVERIQKDSRNCKLSIKASKILTDIHLGDSIAVN
                     GICLTVTHFNHQSFTVDVMNETWSRTALTLLKHGSEVNLERALSINGRLGGHVVTGHI
                     DGTGKISSIKKDDNAVWYQINTQKEILDLIVEKGSITIDGISLTVAKVSKVNFSVSVI
                     PHTLKQTILKSKQVGSTVNLENDILGKYVQKLMDNSPKSEISKELLYQNGF"
     gene            complement(19561..20661)
                     /gene="ribD"
                     /locus_tag="ACL29Z_000247"
     CDS             complement(19561..20661)
                     /gene="ribD"
                     /locus_tag="ACL29Z_000247"
                     /EC_number="1.1.1.193"
                     /EC_number="3.5.4.26"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001284110.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008703 -
                     5-amino-6-(5-phosphoribosylamino)uracil reductase activity
                     [Evidence IEA];
                     GO_function: GO:0008835 -
                     diaminohydroxyphosphoribosylaminopyrimidine deaminase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional
                     diaminohydroxyphosphoribosylaminopyrimidine
                     deaminase/5-amino-6-(5-phosphoribosylamino)uracil
                     reductase RibD"
                     /protein_id="HGR0068621.1"
                     /translation="MSDSKYMKLAIKLAQKGAGYVNPNPMVGAVIVKDNHIIGQGYHE
                     FFGGPHAERNALKNCRKSPVGATLYVTLEPCCHFGKTPPCIDAIIDSGITRVVIGSLD
                     CNPIVSGKGVKILEENNLQVTVGILENECLNLIKSFRKYITQHVPYVFMKYAMSMDGK
                     IATKTNQSKWITEEEARKHVHQLRHYVSAIMVGVNTVIQDDPLLTCRLEEGKNPIRII
                     CDTHLRTPLTSKIVKTANDIKTYIATSSEDKNKMKLYQNHGCEILSIKKKGNHIDLSS
                     LMQHLGNMQIDSLVLEGGSLMNWSALEQQIVDELKIYIAPKIFGGSAKFPVGGEGISL
                     PNDAIRLKPYAFSQIGNDYLIESEVIYPCSQE"
     regulatory      complement(20795..20909)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00050"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="FMN riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="flavin mononucleotide"
                     /db_xref="RFAM:RF00050"
     gene            21066..21659
                     /gene="ruvA"
                     /locus_tag="ACL29Z_000248"
     CDS             21066..21659
                     /gene="ruvA"
                     /locus_tag="ACL29Z_000248"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000271492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009379 - Holliday junction helicase
                     complex [Evidence IEA];
                     GO_function: GO:0003678 - DNA helicase activity [Evidence
                     IEA];
                     GO_function: GO:0009378 - four-way junction helicase
                     activity [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction branch migration protein RuvA"
                     /protein_id="HGR0068622.1"
                     /translation="MYAYLKGIITKITAKYIVLETNGIGYILHVANPYAYSGQVNQEA
                     QIYVHQVVREDAHLLYGFRSEDEKKLFLSLISVSGIGPVSALAIIAADDNAGLVQAIE
                     TKNITYLTKFPKIGKKTAQQMVLDLEGKVVVAGDGLPAKVAVQASAENQELEEAMEAM
                     LALGYKATELKKIKKFFEGTTDTAENYIKSALKMLVK"
     gene            21669..22232
                     /locus_tag="ACL29Z_000249"
     CDS             21669..22232
                     /locus_tag="ACL29Z_000249"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000166575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-3-methyladenine glycosylase I"
                     /protein_id="HGR0068623.1"
                     /translation="MTKRCSWVKMTNPLYIAYHDEEWGQPLHDDQALFELLCMETYQA
                     GLSWETVLNKRQAFREAFHSYQIHSVAEMTDTELEAMLENPAIIRNRAKLFATRANAQ
                     VFLQLQAEYGSFDAYLWSFVEGKTVVNDVPDYRQAPAKTPLSEKLAKDLKKRGFKFTG
                     PVAVLSFLQAAGLVDDHENDCEWKGLK"
     gene            22229..22906
                     /locus_tag="ACL29Z_000250"
     CDS             22229..22906
                     /locus_tag="ACL29Z_000250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000987430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II CAAX endopeptidase family protein"
                     /protein_id="HGR0068624.1"
                     /translation="MMSNKNKGILIFAILYTVLFVFDGVKLLASLMPSVIANYLVYVV
                     LALYGSFLFKDRLIQQWKEIRKTKRKFFFGVLTGWLFLILMTVVFEFVSEMLKQFVRL
                     DGQGLNQSNIQSTFQEQPLLIAVFACVIGPLVEELFFRQVLLHYLQERLPGLLSIIMV
                     GLVFALTHMHSLALSEWIGAVGYLGGGLAFSIIYVKEKENIYYPLLVHMLSNSLSLII
                     LAISIVK"
     gene            complement(23061..24092)
                     /locus_tag="ACL29Z_000251"
     CDS             complement(23061..24092)
                     /locus_tag="ACL29Z_000251"
                     /EC_number="3.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000255096.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="S66 peptidase family protein"
                     /protein_id="HGR0068625.1"
                     /translation="MVSTIGIVSLSSGIIGEDFVKHEVDLGIQRLKDLGLNPIFLPHS
                     LKGLDFIKDHPEARAEDLIHAFSDDSIDMILCAIGGDDTYRLLPYLFENDQLQKVIKQ
                     KIFLGFSDTTMNHLMLHKLGIKTFYGQSFLADICELDKEMLAYSLHYFKELIETGRIS
                     EIRPSDVWYEERTDFSPTALGTPRVSHTNTGFDLLQGSAQFEGKILGGCLESLYDIFD
                     NSRYADSTELCQKYKLFPDLSDWEGKILLLETSEEEPKPEDFKKMLLTLKDTGIFAVI
                     NGLLVGKPMDETFHDDYKEALLDIIDNNIPIVYNLNVGHATPRAIVPFGVHAHVDAQE
                     QVIRFDYNK"
     gene            complement(24347..25030)
                     /locus_tag="ACL29Z_000252"
     CDS             complement(24347..25030)
                     /locus_tag="ACL29Z_000252"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000078028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1129 domain-containing protein"
                     /protein_id="HGR0068626.1"
                     /translation="MSQIDLQKLTKKNQEFVHIATQQFIKDGKTDAEIQTIFEEVIPQ
                     ILEEQSKGTTARSLYGAPTHWAHSFTVKEQYEKEHPKENDDPKLMIMDSALFITSLFA
                     LVSALTTFFAADQAFGYGLITLLLVGLVGGFAFYLMYYFVYQYYGPDMDRSQRPPFWK
                     SVLVILASMFLWLLVFFATSFLPASLNPVLDPLPLAIIGAALLALRFYLKKRLNIRSA
                     SAGPTRYQE"
     gene            complement(25042..25986)
                     /locus_tag="ACL29Z_000253"
     CDS             complement(25042..25986)
                     /locus_tag="ACL29Z_000253"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004250490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046873 - metal ion transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0030001 - metal ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium transporter CorA family protein"
                     /protein_id="HGR0068627.1"
                     /translation="MKQVFLSTTTEFKEIDTLEPGTWINLVNPTQNESLEIANTFDID
                     IADLRAPLDAEEMSRITIEDEYTLIIVDVPVTEERNNRTYYVTIPLGIIITEETIITT
                     CLEPLPVLDVFINRRLRNFYTFMRSRFIFQILYRNAELYLTALRSIDRKSEQIESQLH
                     QSTRNEELIELMELEKTIVYFKASLKTNERVIKKLTSSTSNIKKYLEDEDLLEDTLIE
                     TQQAIEMADIYGNVLHSMTETFASIISNNQNNIMKTLALVTIVMSIPTMVFSAYGMNF
                     KDNEIPLNGEPNAFWLIVFIAFAMSVSLTLYLIHKKWF"
     gene            26118..28949
                     /gene="uvrA"
                     /locus_tag="ACL29Z_000254"
     CDS             26118..28949
                     /gene="uvrA"
                     /locus_tag="ACL29Z_000254"
                     /EC_number="3.1.25.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_process: GO:0006289 - nucleotide-excision repair
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrA"
                     /protein_id="HGR0068628.1"
                     /translation="MQDKIVIHGARAHNLKNIDVEIPRDKLVVVTGLSGSGKSSLAFD
                     TLYAEGQRRYVESLSAYARQFLGNMEKPDVDAIDGLSPAISIDQKTTSKNPRSTVGTT
                     TEINDYLRLLYARVGTPYCINGHGAINASSVEQIVDKVLELPERQRLQILAPVIRKKK
                     GQHKSVIEKVQKDGYVRVRVDGEVYDVTEVPELSKSKQHNIDVVVDRIVIKEGIRSRL
                     FDSIEAALRIAEGYVIIDTMDDSELLFSEHYACPVCGFTVPELEPRLFSFNAPFGSCS
                     ECDGLGIKLEVDTDLVVPDASKTLHEGALAPWNPISSNYYPNMLEQAMKVFGVAMDKP
                     FEDLSEEDKNLILYGSDGKEFHFHYENEFGGVRDIDIPFEGVINNIKRRYHETNSDYT
                     RTQMRLYMNELTCGTCQGYRLNDQALSVRVGGQQGPHIGEISDLSIADHLDLVSQLTL
                     SENEAIIARPILKEIKDRLTFLNNVGLNYLTLSRSAGTLSGGESQRIRLATQIGSNLS
                     GVLYILDEPSIGLHQRDNDRLIASLKKMRDLGNTLIVVEHDEDTMREADYLIDVGPGA
                     GVFGGEIVAAGTPKQVARNSKSITGQYLSGKRVIPVPEERRVGNGRFIEVIGARENNL
                     QNVTARFPLGKFIAVTGVSGSGKSTLINSILKKAIAQKLNRNSDKPGKFKTITGIEHV
                     DRLIDIDQSPIGRTPRSNPATYTGVFDDIRDLFAQTNEAKIRGYKKGRFSFNVKGGRC
                     EACSGDGIIKIEMHFLPDVYVACEVCHGTRYNSETLEVHYKEKNISQVLDMTVNDAVE
                     FFQHIPKIQRKLQTIKDVGLGYVTLGQPATTLSGGEAQRMKLASELHKRSTGKSFYIL
                     DEPTTGLHTEDIARLLKVLARFVDDGNTVLVIEHNLDVIKTADHIIDLGPEGGVGGGT
                     IIVTGTPEEVAANEASYTGHYLKGKLHHE"
     gene            28942..30003
                     /locus_tag="ACL29Z_000255"
     CDS             28942..30003
                     /locus_tag="ACL29Z_000255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466358.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008233 - peptidase activity [Evidence
                     IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="M24 family metallopeptidase"
                     /protein_id="HGR0068629.1"
                     /translation="MNKRVQAFLAKMQEKELDGVIINNLKNVYYLTGFWGSNGTVFIS
                     RDRQVLVTDSRYIIAAKQETSGFEIVADRDELAVIAGIVKDMGLTRIGFEDEISVSYY
                     HRMQAAFAGLDLLPQTQFVEGLRMIKDEAEIAAIRKACSISDQAFRDALDFIKPGKTE
                     IEIANFLDFRMRELGASGLSFDTILASGINSSKPHAHPMHKPVELGEAITMDFGCLYD
                     HYVSDMTRTIYLGHVSDEQAEIYNTVLKANQALIDQAKAGLGFRDFDKIPRDIIIEAG
                     YGDYFTHGIGHGIGLDIHEEPYFSQTSTETIKTGMALTDEPGIYIEGKYGVRIEDDIL
                     ITETGCELLTLAPKELIVI"
     gene            30135..30533
                     /gene="spx"
                     /locus_tag="ACL29Z_000256"
     CDS             30135..30533
                     /gene="spx"
                     /locus_tag="ACL29Z_000256"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017768833.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator Spx"
                     /protein_id="HGR0068630.1"
                     /translation="MIKIYTVSSCTSCKKAKTWLNAHQLSYKEQNLGKEGITREELLD
                     ILTKTDNGIASIVSSKNRYAKALGVDIEDLSVNEVLNLIMETPRILKSPILVDEKRLQ
                     VGYKEDDIRAFLPRSVRNVENAEARLRAAL"
     gene            30599..31168
                     /locus_tag="ACL29Z_000257"
     CDS             30599..31168
                     /locus_tag="ACL29Z_000257"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000725124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SP0191 family lipoprotein"
                     /protein_id="HGR0068631.1"
                     /translation="MKKIVLVSLAFLFVLVGCGQKKETGTATKTEKDTLQSALPVIEN
                     AEKNTVVTKTLVLPKSDDGSQQTQTITYKDKTFLSLTIQQKRPVSDELKTYIDQHGVE
                     ETQKALLEAEEKDKSIIEARKLAGFKLETKLLSATELQTTTSFDFQVLDVKKASQLEH
                     LKNIGLENLLKNEPSKYISDRLANGATEQ"
     gene            31255..31521
                     /locus_tag="ACL29Z_000258"
     CDS             31255..31521
                     /locus_tag="ACL29Z_000258"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004250500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IreB family regulatory phosphoprotein"
                     /protein_id="HGR0068632.1"
                     /translation="MGFTEETVRFKLDDSNKKEISETLTDVYASLNDKGYNPINQIVG
                     YVLSGDPAYVPRYNNARNQIRKYERDEIVEELVRYYLKGQGVDL"
     gene            31525..31944
                     /gene="ruvX"
                     /locus_tag="ACL29Z_000259"
     CDS             31525..31944
                     /gene="ruvX"
                     /locus_tag="ACL29Z_000259"
                     /EC_number="3.1.21.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003090938.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006364 - rRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction resolvase RuvX"
                     /protein_id="HGR0068633.1"
                     /translation="MRIMGLDVGSKTVGVAISDPLGFTAQGLEIIQINEEQGQFGFDR
                     VKELVDTYKVERFVVGLPKNMNNTSGPRVEASQAYGAKLEEFFGLPVDYQDERLTTVA
                     AERMLIEQADISRNKRKKVIDKLAAQLILQNYLDRKF"
     gene            31960..32265
                     /locus_tag="ACL29Z_000260"
     CDS             31960..32265
                     /locus_tag="ACL29Z_000260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1292 domain-containing protein"
                     /protein_id="HGR0068634.1"
                     /translation="MSHDHNHDHEERELITLVDEQGNETLFEILLTIDGKEEFGKNYV
                     LLVPVNAEEDEDGQVEIQAYSFIENEDGTEGELQPIPEDSEDEWNMIEEVFNSFMEE"
     gene            32473..33723
                     /locus_tag="ACL29Z_000261"
     CDS             32473..33723
                     /locus_tag="ACL29Z_000261"
                     /EC_number="6.3.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000464354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004326 - tetrahydrofolylpolyglutamate
                     synthase activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008841 - dihydrofolate synthase activity
                     [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0006730 - one-carbon metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="folylpolyglutamate synthase/dihydrofolate
                     synthase family protein"
                     /protein_id="HGR0068635.1"
                     /translation="MFEVEEWLHSRIGLNFRSGLGRMQQAVDLLGNPEKSYPIIHVTG
                     TNGKGSTIAFMRELFMGHGKKVATFTSPHIVSINDRICINGQPIADTDFIRLAEQVKE
                     MEKTLLQTHDQLSFFELLTLIAFLYFREQEVDLVLLEVGIGGLLDTTNVVTGELAVIT
                     SIGLDHQETLGDSLEAIAEQKAGIFKAGKKAVIAKLAPEARLVCQKKAESLAVDLYQA
                     GQDFSMLNGDFSSSLVNLSQLKIGLEGAYQQENAALALQTFLLFMGERKETVDEQAVR
                     QALEKTHWAGRLERIRPQIYLDGAHNLPALTRLVEFIKEKEQEGYRPQILFGALKRKD
                     YQGMLAYLTQKLPQVELKVTGFDYQGSLDETDVIGYDIVPSYREFISSFEERADAQDL
                     LFVTGSLYFISEVRGYLLGHEQIN"
     gene            33811..34281
                     /locus_tag="ACL29Z_000262"
     CDS             33811..34281
                     /locus_tag="ACL29Z_000262"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SP_0198 family lipoprotein"
                     /protein_id="HGR0068636.1"
                     /translation="MTFKTAALSIVSLASVSLLVACSQRTQPVQQPVAQQQVQQPAQQ
                     PAQQNTNTANAGSNQNQAAPVQNQPVAQPTDIDGTYTGQDDGDRITLVVTGTTGTWTE
                     LESDGDQKVKQVTFDAANQRMIIGDDVKIYTVNGNQIVVDDMDRDPSDQIVLTK"
     gene            34533..36065
                     /gene="cls"
                     /locus_tag="ACL29Z_000263"
     CDS             34533..36065
                     /gene="cls"
                     /locus_tag="ACL29Z_000263"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000877342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008808 - cardiolipin synthase activity
                     [Evidence IEA];
                     GO_function: GO:0016780 - phosphotransferase activity, for
                     other substituted phosphate groups [Evidence IEA];
                     GO_process: GO:0032049 - cardiolipin biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cardiolipin synthase"
                     /protein_id="HGR0068637.1"
                     /translation="MKYRKFQLLMSKYGFSLSIMLLELCLVFGLFLYLGRMAPILWIT
                     VLILLSIITIISIVNRNTTPENKVTWLLVAFVPVFGPLLYLMFGERRLSKKEIKQLKK
                     LGSMHFQEANSQLLKEELKESDKAAYGVIKSLLSMDTNADIYDQTASTFFPNGEAMWK
                     KMVEDLKKAEKFIFLEYYIIEEGLMWNRILDILEQKVAQGVEVKMLYDDIGCMATLTG
                     DYAHRLRQLGIEAHKFNKVIPRLTVAYNNRDHRKILIVDGQIAYTGGVNLADEYINHV
                     ERFGYWKDSGIRLDGLAVKALTRLFLTTWYINRGEISDFDQYHLENHSIPSDGLTIPY
                     GSGPKPIFRAQVGKKVYQSLINQATESVYITTPYLIIDYDLTETIKNAAMRGVDVRII
                     TPYIPDKKFIQLVTRGAYPDLLSAGVRIYEYSPGFIHSKQMLVDEDFAVVGTINLDYR
                     SLVHHYENAVLLYKTPSIREIARDFRNIFADSQEVYPHSIKTSWYQKLVKEIAQLFAP
                     IL"
     gene            36323..37861
                     /locus_tag="ACL29Z_000264"
     CDS             36323..37861
                     /locus_tag="ACL29Z_000264"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844448.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="damage-inducible protein CinA"
                     /protein_id="HGR0068638.1"
                     /translation="MSVYGRVEEVHKENREPLEYQIEQESHHRESSRLPLVKILLWST
                     LVTGITLGVPLLLDLMSAQEVQDFYAGWALHQTGKIYSDYYGSQGLLYYLLTYVSQGG
                     FFFAIFEWLALVAGGFFLFRSADTLTEQGDQAGHLVTIFYMLVTGLAFGGGYATLLAL
                     PFLFAAFSLVAAYLSNPSHDKGFVRIGLALAGGFFFAPLSSLLFIAVVSLGLLVFNLG
                     HRRFVHGFYQFLAVALGFSLVFYPTAYYSAATGSFGDAISGIRYPIDSIRFDFTSKIL
                     ENMFFYGLLSLGLGFVVCIFLGLFQSKPFKLYVISVPASLVVILGLILLFFSQEPLHA
                     SYLMVVFPVFLLLLVTNIKSQQRGRSARRSRRETPVSLWSRFFKGNLYLLVFGFVYLL
                     SVPFLMKFVLYPVPYQERNRLADLVKEETNTEDAIYAWDDTATLYRKSERLSPSAILS
                     PLHYTATEENRNKLLNDLKEKQPKVIVVNDKVVVWSEVETLLKENYQQVKTDYSEFKV
                     YKIK"
     gene            37981..40188
                     /gene="nrdD"
                     /locus_tag="ACL29Z_000265"
     CDS             37981..40188
                     /gene="nrdD"
                     /locus_tag="ACL29Z_000265"
                     /EC_number="1.17.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004239081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008998 - ribonucleoside-triphosphate
                     reductase (thioredoxin) activity [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic ribonucleoside-triphosphate reductase"
                     /protein_id="HGR0068639.1"
                     /translation="MIALEEKITILPTLFVEKRDGRRVVFDVDKIDKALHKAADKVMD
                     VTPLVEKRLNDLTERIITEIHSRFPQGIKIYEIQNIVEHELLEAKEYALAEEYITYRT
                     QRDFERSKATDINFSIHKLLNKDQTVVNENANKDSDVFNTQRDLTAGIVGKSIGLQML
                     PKHVANAHQKGDIHYHDLDYSPYTPMTNCCLVDFKGMLENGFKIGNAEVESPKSIQTA
                     TAQISQIIANVASSQYGGCSADRIDEILAPYAEKNYQKHLKDAEEWVLPEKREDYAWK
                     KTQKDIYDAMQSLEYEINTLFTSNGQTPFTSLGFGLGTSRFEREIQKAILNIRIKGLG
                     SEHRTAIFPKLIFTLKRGLNLEEGTPNYDIKQLALECATKRMYPDVLSYDKIVDLTGS
                     FKVPMGCRSFLQGWKDENGVEVNSGRMNLGVVTVNLPRIALESEGDMNKFWEIFNERM
                     NIAEDALVYRVERTKEATPANAPILYQYGAFGHRLGKEESVDQLFKNRRATVSLGYIG
                     LYEVATVFFGNSWESNPDAKEFTLDIIHDMKRRVEEWSDQYGYHFSIYSTPSESLTDR
                     FCRLDIDKFGSIPDITDKEYYTNSFHYDVRKNPTPFEKLDFEKVYPEAGASGGFIHYC
                     EYPVLQQNPKALEAVWDYAYDRVGYLGTNTPIDRCYKCDFEGDFEPTERGFACPNCGN
                     SDPKTVDVVKRTCGYLGNPQARPMVNGRHKEIAARVKHMNGSTIKIAGHQVTN"
     gene            40200..40340
                     /locus_tag="ACL29Z_000266"
     CDS             40200..40340
                     /locus_tag="ACL29Z_000266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000521630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0068640.1"
                     /translation="MGKYQLDDKGRAQVTRYHEKYSKGGAGKKERLLSFREQFLNKNK
                     KK"
     gene            40384..40890
                     /locus_tag="ACL29Z_000267"
     CDS             40384..40890
                     /locus_tag="ACL29Z_000267"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000423398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HGR0068641.1"
                     /translation="MELRRPRLADKKAVLDMMTEFEKSQSAHDGGFWDTENFVYEEWL
                     ESNQEQEMGINLPEGWVPAIQLVAFSEKGQAVGFLNLRLRLSNFLLEEGGHIGYSIRP
                     SERGKGYAKETLRQGLQVAKEKNIKKALVTCSVNNPASRAVILANGGIFEDAHNGVER
                     YWIEVANE"
     gene            40883..41473
                     /gene="nrdG"
                     /locus_tag="ACL29Z_000268"
     CDS             40883..41473
                     /gene="nrdG"
                     /locus_tag="ACL29Z_000268"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001064213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0043365 -
                     [formate-C-acetyltransferase]-activating enzyme activity
                     [Evidence IEA];
                     GO_function: GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic ribonucleoside-triphosphate reductase
                     activating protein"
                     /protein_id="HGR0068642.1"
                     /translation="MNNPKPQEWKSEELSQGRIIDYKAFNFVDGEGVRNSLYVSGCMF
                     HCEGCYNVATWSFNAGIPYTAELEEQIMADLAQPYVQGLTLLGGEPFLNTGILLPLVK
                     RIRKELSDKDIWSWTGYTWEEMMLETPDKLELLSLIDILVDGRYDRTKRNLMLQFRGS
                     SNQRIIDVQKSLKSGQVVIWDKLNDGKESYEQVKRE"
     gene            41470..42087
                     /locus_tag="ACL29Z_000269"
     CDS             41470..42087
                     /locus_tag="ACL29Z_000269"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000725987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uridine kinase"
                     /protein_id="HGR0068643.1"
                     /translation="MKKKDLVDQLVSEIETGKVRTLGIYGHGASGKSTSAQELYQALD
                     STTVNLLETDPYITSGRHLVVPKDAPNQKVTAGLPVAHELESLQRDILALQASMDVLT
                     IEEPWKASEVLSGAKPILIVEGMSVGFRPKELFEKTICFYTDEETELKRRLARDTTVR
                     NRDASFILASHQMRREQYLRYYKETESKADILVDQSEDKFDVKRT"
     gene            42353..42661
                     /gene="rpsJ"
                     /locus_tag="ACL29Z_000270"
     CDS             42353..42661
                     /gene="rpsJ"
                     /locus_tag="ACL29Z_000270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003046044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S10"
                     /protein_id="HGR0068644.1"
                     /translation="MANKKIRIRLKAYEHRTLDTAAAKIVESATRTGAQVAGPIPLPT
                     ERSLYTIIRATHKYKDSREQFEMRTHKRLIDIVNPTQKTVDALMKLDLPSGVNVEIKL
                     "
     gene            42878..43504
                     /gene="rplC"
                     /locus_tag="ACL29Z_000271"
     CDS             42878..43504
                     /gene="rplC"
                     /locus_tag="ACL29Z_000271"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L3"
                     /protein_id="HGR0068645.1"
                     /translation="MTKGILGKKVGMTQIFTEAGELIPVTVIEATPNVVLQVKTVETD
                     GYNAIQVGFDDKREVLSNKPAKGHVAKANTAPKRFIREFKNVEGLEVGAEITVETFAA
                     GDVVDVTGTSKGKGFQGVIKRHGQSRGPMAHGSRYHRRPGSMGPVAPNRVFKGKNLAG
                     RMGGDRVTIQNLEVVQVVPEKNVILIKGNVPGAKKSLITIKSAVKAGK"
     gene            43529..44152
                     /gene="rplD"
                     /locus_tag="ACL29Z_000272"
     CDS             43529..44152
                     /gene="rplD"
                     /locus_tag="ACL29Z_000272"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0022625 - cytosolic large ribosomal
                     subunit [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L4"
                     /protein_id="HGR0068646.1"
                     /translation="MANVTLFDQTGKEAGQVVLSDAVFGIEPNESVVFDVIISQRASL
                     RQGTHAVKNRSAVSGGGRKPWRQKGTGRARQGSIRSPQWRGGGVVFGPTPRSYGYKLP
                     QKVRRLALKSVYSEKVAENKFVAVDALSFTAPKTAEFAKVLAALSIDSKVLVILEEGN
                     EFAALSARNLPNVKVATATTASVLDIANSDKLLVTQAAISKIEEVLA"
     gene            44152..44448
                     /locus_tag="ACL29Z_000273"
     CDS             44152..44448
                     /locus_tag="ACL29Z_000273"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007518994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L23"
                     /protein_id="HGR0068647.1"
                     /translation="MNLYDVIKKPVITESSMAQLEAGKYVFEVDTRAHKLLIKQAVEA
                     AFEGVKVANVNTINVKPKAKRVGRYTGFTNKTKKAIITLTADSKAIELFAAEAE"
     gene            44466..45299
                     /gene="rplB"
                     /locus_tag="ACL29Z_000274"
     CDS             44466..45299
                     /gene="rplB"
                     /locus_tag="ACL29Z_000274"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019790357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015934 - large ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_function: GO:0016740 - transferase activity [Evidence
                     IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L2"
                     /protein_id="HGR0068648.1"
                     /translation="MGIRVYKPTTNGRRNMTSLDFAEITTSTPEKSLLVALKSKAGRN
                     NNGRITVRHQGGGHKRFYRLVDFKRNKDNVEAVVKTIEYDPNRSANIALVHYTDGVKA
                     YIIAPKGLEVGQRIVSGPEADIKVGNALPLANIPVGTLIHNIELKPGRGGELVRAAGA
                     SAQVLGSEGKYVLVRLQSGEVRMILGTCRATVGVVGNEQHGLVNLGKAGRSRWKGIRP
                     TVRGSVMNPNDHPHGGGEGKAPVGRKAPSTPWGKPALGLKTRNKKAKSDKLIVRRRNE
                     K"
     gene            45403..45684
                     /gene="rpsS"
                     /locus_tag="ACL29Z_000275"
     CDS             45403..45684
                     /gene="rpsS"
                     /locus_tag="ACL29Z_000275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000533767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015935 - small ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S19"
                     /protein_id="HGR0068649.1"
                     /translation="MGRSLKKGPFVDEHLMKKVEAQANDEKKKVIKTWSRRSTIFPSF
                     IGYTIAVYDGRKHVPVYIQEDMVGHKLGEFAPTRTYKGHAADDKKTRRK"
     gene            45696..46040
                     /gene="rplV"
                     /locus_tag="ACL29Z_000276"
     CDS             45696..46040
                     /gene="rplV"
                     /locus_tag="ACL29Z_000276"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018371349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015934 - large ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L22"
                     /protein_id="HGR0068650.1"
                     /translation="MAEITSAKAMARTVRVSPRKSRLVLDNIRGKSVADAIAILTFTP
                     NKAAEIILKVLNSAVANAENNFGLDKANLVVSEAFANEGPTMKRFRPRAKGSASPINK
                     RTAHITVAVAEK"
     gene            46053..46706
                     /gene="rpsC"
                     /locus_tag="ACL29Z_000277"
     CDS             46053..46706
                     /gene="rpsC"
                     /locus_tag="ACL29Z_000277"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000529931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S3"
                     /protein_id="HGR0068651.1"
                     /translation="MGQKVHPIGMRVGIIRDWDAKWYAEKEYADYLHEDLAIRKFVQK
                     ELADAAVSTIEIERAVNKVNVSLHTAKPGMVIGKGGANVDALRAKLNKLTGKQVHINI
                     IEIKQPDLDAHLVGEGIARQLEQRVAFRRAQKQAIQRAMRAGAKGIKTQVSGRLNGAD
                     IARAEGYSEGTVPLHTLRADIDYAWEEADTTYGKLGVKVWIYRGEVLPARKNTKGGK"
     gene            46710..47123
                     /gene="rplP"
                     /locus_tag="ACL29Z_000278"
     CDS             46710..47123
                     /gene="rplP"
                     /locus_tag="ACL29Z_000278"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003029477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_function: GO:0019843 - rRNA binding [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L16"
                     /protein_id="HGR0068652.1"
                     /translation="MLVPKRVKHRREFRGKMRGEAKGGKEVAFGEYGLQATTSHWITN
                     RQIEAARIAMTRYMKRGGKVWIKIFPHKSYTAKAIGVRMGSGKGAPEGWVAPVKRGKV
                     MFEIAGVSEEIAREALRLASHKLPVKCKFVKREAE"
     gene            47133..47339
                     /gene="rpmC"
                     /locus_tag="ACL29Z_000279"
     CDS             47133..47339
                     /gene="rpmC"
                     /locus_tag="ACL29Z_000279"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006739716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L29"
                     /protein_id="HGR0068653.1"
                     /translation="MKLNEVKEFVKELRGLSQEELAKRENELKKELFELRFQAATGQL
                     EQTARLKEVKKQIARIKTVQSEAK"
     gene            47364..47624
                     /gene="rpsQ"
                     /locus_tag="ACL29Z_000280"
     CDS             47364..47624
                     /gene="rpsQ"
                     /locus_tag="ACL29Z_000280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006738952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S17"
                     /protein_id="HGR0068654.1"
                     /translation="MERNNRKVLVGRVVSDKMDKTITVVVETKRNHPVYGKRINYSKK
                     YKAHDENNVAKEGDIVRIMETRPLSATKRFRLVEVVEEAVII"
     gene            47650..48018
                     /gene="rplN"
                     /locus_tag="ACL29Z_000281"
     CDS             47650..48018
                     /gene="rplN"
                     /locus_tag="ACL29Z_000281"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012727667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015934 - large ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L14"
                     /protein_id="HGR0068655.1"
                     /translation="MIQTETRLKVADNSGAREILTIKVLGGSGRKFANIGDVIVASVK
                     QATPGGAVKKGDVVKAVIVRTKSGARRADGSYIKFDENAAVIIREDKTPRGTRIFGPV
                     ARELREGGFMKIVSLAPEVL"
     gene            48096..48401
                     /gene="rplX"
                     /locus_tag="ACL29Z_000282"
     CDS             48096..48401
                     /gene="rplX"
                     /locus_tag="ACL29Z_000282"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011921687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L24"
                     /protein_id="HGR0068656.1"
                     /translation="MFVKKGDKVRVIAGKDKGTEAVVLTALPKVNKVIVEGVNIVKKH
                     QRPTNELPQGGIIEKEAAIHVSNVQVLDKNGVAGRVGYKFVDGKKVRYNKKSGEVLD"
     gene            48425..48967
                     /gene="rplE"
                     /locus_tag="ACL29Z_000283"
     CDS             48425..48967
                     /gene="rplE"
                     /locus_tag="ACL29Z_000283"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018376779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L5"
                     /protein_id="HGR0068657.1"
                     /translation="MANRLKEKYLNEVVPALTEQFNYSSVMAVPKVDKIVLNMGVGEA
                     VSNAKSLEKAAEELALISGQKPLITKAKKSIAGFRLREGVAIGAKVTLRGERMYEFLD
                     KLVSVSLPRVRDFHGVPTKSFDGRGNYTLGVKEQLIFPEINFDDVDKTRGLDIVIVTT
                     ANTDEESRALLTGLGMPFAK"
     gene            48985..49254
                     /gene="rpsN"
                     /locus_tag="ACL29Z_000284"
     CDS             48985..49254
                     /gene="rpsN"
                     /locus_tag="ACL29Z_000284"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006738440.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S14"
                     /protein_id="HGR0068658.1"
                     /translation="MAKKSMVAREAKRQKIVDRYAEKRAALKAAGDYEGLSKLPRNAS
                     PTRLHNRCRVTGRPHSVYRKFGLSRIAFRELAHKGQIPGVTKASW"
     gene            49539..49937
                     /gene="rpsH"
                     /locus_tag="ACL29Z_000285"
     CDS             49539..49937
                     /gene="rpsH"
                     /locus_tag="ACL29Z_000285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009754342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S8"
                     /protein_id="HGR0068659.1"
                     /translation="MVMTDPIADFLTRIRNANQAKHEVLEVPASNIKKGIAEILKREG
                     FVKNVEIIEDDKQGVIRVFLKYGPNGEKVITNLKRVSKPGLRVYKKREDLPKVLNGLG
                     IAILSTSEGLLTDKEARQKNVGGEVIAYVW"
     gene            50129..50665
                     /gene="rplF"
                     /locus_tag="ACL29Z_000286"
     CDS             50129..50665
                     /gene="rplF"
                     /locus_tag="ACL29Z_000286"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_function: GO:0019843 - rRNA binding [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L6"
                     /protein_id="HGR0068660.1"
                     /translation="MSRIGNKVIVLPAGVELANNDNVVTVKGPKGELTREFSKDIEIR
                     VEGTEVTLHRPNDSKEMKTIHGTTRALLNNMVVGVSEGFKKELEMRGVGYRAQLQGSK
                     LVLAVGKSHPDEVEAPEGITFELPNPTTIVVSGISKEVVGQTAAYVRSLRSPEPYKGK
                     GIRYVGEFVRRKEGKTGK"
     gene            50749..51105
                     /gene="rplR"
                     /locus_tag="ACL29Z_000287"
     CDS             50749..51105
                     /gene="rplR"
                     /locus_tag="ACL29Z_000287"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018374469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L18"
                     /protein_id="HGR0068661.1"
                     /translation="MISKPDKNKLRQKRHRRVRGKLSGTADRPRLNVFRSNTGIYAQV
                     IDDVAGVTLASASTLDKEVSKGTKTEQAVAVGKLVAERANAKGISEVVFDRGGYLYHG
                     RVKALADAARENGLKF"
     gene            51123..51617
                     /gene="rpsE"
                     /locus_tag="ACL29Z_000288"
     CDS             51123..51617
                     /gene="rpsE"
                     /locus_tag="ACL29Z_000288"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018376782.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015935 - small ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S5"
                     /protein_id="HGR0068662.1"
                     /translation="MAFKDNAVELEERVVAVNRVTKVVKGGRRLRFAALVVVGDHNGR
                     VGFGTGKAQEVPEAIRKAVDDAKKNLIEVPMVGTTIPHEVLSEFGGAKVLLKPAVEGS
                     GVAAGGAVRAVVELAGVADITSKSLGSNTPINIVRATVEGLKQLKRAEEIAALRGISV
                     SDLA"
     gene            51631..51813
                     /gene="rpmD"
                     /locus_tag="ACL29Z_000289"
     CDS             51631..51813
                     /gene="rpmD"
                     /locus_tag="ACL29Z_000289"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018377726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015934 - large ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L30"
                     /protein_id="HGR0068663.1"
                     /translation="MAQIKITLTKSPIGCIPSQRKTVVALGLGKLNSSVIKEDNAAIR
                     GMITAVSHLVTVEEVN"
     gene            51958..52398
                     /gene="rplO"
                     /locus_tag="ACL29Z_000290"
     CDS             51958..52398
                     /gene="rplO"
                     /locus_tag="ACL29Z_000290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004225266.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015934 - large ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L15"
                     /protein_id="HGR0068664.1"
                     /translation="MKLHELKPAEGSRKVRNRVGRGTSSGNGKTSGRGQKGQKARSGG
                     GVRLGFEGGQTPLFRRLPKRGFTNINAKEYAIVNLDQLNVFEDGAEVTPVVLIEAGIV
                     KAEKSGIKILGNGELTKKLTVKAAKFSKSAEEAITAKGGSVEVI"
     gene            52411..53721
                     /gene="secY"
                     /locus_tag="ACL29Z_000291"
     CDS             52411..53721
                     /gene="secY"
                     /locus_tag="ACL29Z_000291"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001860634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0015031 - protein transport [Evidence IEA];
                     GO_process: GO:0043952 - protein transport by the Sec
                     complex [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecY"
                     /protein_id="HGR0068665.1"
                     /translation="MFFKLLREALKVKQVRSKILFTIFIVLVFRIGTSITVPGVNANS
                     LNALSGLSFLNMLSLVSGNALKNFSIFALGVSPYITASIVVQLLQMDILPKFVEWGKQ
                     GEVGRRKLNQATRYIALVLAFVQSIGITAGFNTLAGAQLIKTALTPQVFLTIGIILTA
                     GSMIVTWLGEQITDKGYGNGVSMIIFAGIVSSIPEMIQGIYVDYFVNVPSSRITSSII
                     FVIILIITVLLIIYFTTYVQQAEYKIPIQYTKVAQGAPSSSYLPLKVNPAGVIPVIFA
                     SSITAAPAAILQFLSATGHDWAWVRVAQEMLATTSPTGIAMYALLIILFTFFYTFVQI
                     NPEKAAESLQKSGAYIHGVRPGKGTEEYMSKLLRRLATVGSLFLGVISILPIAAKDVF
                     GLSDVVAFGGTSLLIIISTGIEGIKQLEGYLLKRKYVGFMDRTE"
     gene            53872..54510
                     /locus_tag="ACL29Z_000292"
     CDS             53872..54510
                     /locus_tag="ACL29Z_000292"
                     /EC_number="2.7.4.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001050429.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylate kinase"
                     /protein_id="HGR0068666.1"
                     /translation="MNLLIMGLPGAGKGTQAAKIVEQFHVAHISTGDMFRAAMANQTE
                     MGVLAKSYIDKGELVPDEVTNGIVKERLSQDDIKETGFLLDGYPRTIEQAHALDKTLN
                     ELGIELEGVINIEVNPDSLLERLSGRIIHRVTGETFHKVFNPPVDYKEEDYYQREDDK
                     PETVKRRLDVNIAQGEPIIAHYRAKGLVHDIEGNQDINDVFSDIEKVLTNLK"
     gene            54627..54845
                     /gene="infA"
                     /locus_tag="ACL29Z_000293"
     CDS             54627..54845
                     /gene="infA"
                     /locus_tag="ACL29Z_000293"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003130554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003743 - translation initiation factor
                     activity [Evidence IEA];
                     GO_process: GO:0006413 - translational initiation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-1"
                     /protein_id="HGR0068667.1"
                     /translation="MAKDDVIEVEGKVVDTMPNAMFTVELENGHQILATVSGKIRKNY
                     IRILAGDRVTVEMSPYDLTRGRITYRFK"
     gene            54870..54986
                     /gene="rpmJ"
                     /locus_tag="ACL29Z_000294"
     CDS             54870..54986
                     /gene="rpmJ"
                     /locus_tag="ACL29Z_000294"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013773089.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L36"
                     /protein_id="HGR0068668.1"
                     /translation="MKVRPSVKPICEYCKVIRRNGRVMVICPANPKHKQRQG"
     gene            55004..55369
                     /gene="rpsM"
                     /locus_tag="ACL29Z_000295"
     CDS             55004..55369
                     /gene="rpsM"
                     /locus_tag="ACL29Z_000295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S13"
                     /protein_id="HGR0068669.1"
                     /translation="MARIAGVDIPNDKRVVISLTYVYGIGLATSKKILAAAGISEDVR
                     VRDLTSDQEDAIRREVDAIKVEGDLRREVNLNIKRLMEIGSYRGIRHRRGLPVRGQNT
                     KNNARTRKGKAVAIAGKKK"
     gene            55387..55770
                     /gene="rpsK"
                     /locus_tag="ACL29Z_000296"
     CDS             55387..55770
                     /gene="rpsK"
                     /locus_tag="ACL29Z_000296"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003130556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S11"
                     /protein_id="HGR0068670.1"
                     /translation="MAKPTRKRRVKKNIESGIAHIHATFNNTIVMITDVHGNAIAWSS
                     AGALGFKGSRKSTPFAAQMASEAAAKSAQEHGLKSVEVTVKGPGSGRESAIRALAAAG
                     LEVTAIRDVTPVPHNGARPPKRRRV"
     gene            55813..56748
                     /locus_tag="ACL29Z_000297"
     CDS             55813..56748
                     /locus_tag="ACL29Z_000297"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000568977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit alpha"
                     /protein_id="HGR0068671.1"
                     /translation="MIEFEKPNITKIDENKDYGKFVIEPLERGYGTTLGNSLRRVLLA
                     SLPGAAVTSINIDGVLHEFDTVPGVREDVMQIILNIKGIAVKSYVEDEKIIELDVEGP
                     AEVTAGDILTDSDIEIVNPDHYLFTIGEGSSLKATMTVNSGRGYVPADENKKDNAPVG
                     TLAVDSIYTPVTKVNYQVEPARVGSNDGFDKLTLEILTNGTIIPEDALGLSARILTEH
                     LDLFTNLTEIAKSTEVMKEADTESDDRILDRTIEELDLSVRSYNCLKRAGINTVHDLT
                     EKSEAEMMKVRNLGRKSLEEVKLKLIDLGLGLKDK"
     gene            56760..57146
                     /gene="rplQ"
                     /locus_tag="ACL29Z_000298"
     CDS             56760..57146
                     /gene="rplQ"
                     /locus_tag="ACL29Z_000298"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002887523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L17"
                     /protein_id="HGR0068672.1"
                     /translation="MAYRKLGRTSSQRKAMLRDLTTDLLINESIVTTEARAKEIRKTV
                     EKMITLGKRGDLHARRQAAAFVRNEIASENYDEATDKYTSTTALQKLFSEIAPRYAER
                     NGGYTRILKTEPRRGDAAPMAIIELV"
     gene            57411..57677
                     /locus_tag="ACL29Z_000299"
     CDS             57411..57677
                     /locus_tag="ACL29Z_000299"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002905356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ACT domain-containing protein"
                     /protein_id="HGR0068673.1"
                     /translation="MKAIITVVGKDKSGIVAGVSGKIAELGLNIDDISQTVLDEYFTM
                     MAIVSSDEKQDFTYLRNEFEAFGQTLNVKINIQSAAIFEAMYNI"
     gene            57687..59024
                     /locus_tag="ACL29Z_000300"
     CDS             57687..59024
                     /locus_tag="ACL29Z_000300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018166727.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PFL family protein"
                     /protein_id="HGR0068674.1"
                     /translation="MDIRQVTETIAMIEEQNFDIRTITMGISLLDCIDPDINRAAEKI
                     YQKITTKAANLVAVGDEIAAELGIPIVNKRVSVTPISLIGAATDATDYVVLAKALDKA
                     AKEIGVDFIGGFSALVQKGYQKGDEILINSIPRALAETDKVCSSVNIGSTKSGINMTA
                     VADMGRIIKETANLSDMGVAKLVVFANAVEDNPFMAGAFHGVGEADVIINVGVSGPGV
                     VKRALEKVRGQSFDVVAETVKKTAFKITRIGQLVGQMASERLGVEFGIVDLSLAPTPA
                     VGDSVARVLEEMGLETVGTHGTTAALALLNDQVKKGGVMACNQVGGLSGAFIPVSEDE
                     GMIAAVQNGSLNLEKLEAMTAICSVGLDMIAIPEDTPAETIAAMIADEAAIGVINMKT
                     TAVRIIPKGKEGDMIEFGGLLGTAPVMRVNGASSVDFISRGGQIPAPIHSFKN"
     gene            59268..59960
                     /locus_tag="ACL29Z_000301"
     CDS             59268..59960
                     /locus_tag="ACL29Z_000301"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016791 - phosphatase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HGR0068675.1"
                     /translation="MVKVRLYLVRHGKTMFNTIGRAQGWSDTPLTAEGERGIQELGIG
                     LRESDLQFERAYSSDSGRTIQTMGIILEELGLQGKIPYRMDKRIREWCFGSFDGAYDG
                     DLFMGIIPRIFNVDHVHQLSYAELAEGLVEVDTAGWAEGWEKLSGRIKEGFEMIAKEM
                     EDQGGGNALVVSHGMTIGTIVYLINGMHPHGLDNGSVTILEYEDGQFRVEVVGDRSYR
                     ELGREKMEEGSI"
     gene            complement(60063..61708)
                     /locus_tag="ACL29Z_000302"
                     /pseudo
     CDS             complement(60063..61708)
                     /locus_tag="ACL29Z_000302"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520796.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0006826 - iron ion transport [Evidence
                     IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
     gene            complement(61698..62789)
                     /locus_tag="ACL29Z_000303"
     CDS             complement(61698..62789)
                     /locus_tag="ACL29Z_000303"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001289361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGR0068676.1"
                     /translation="MSEIEIINAKKIYHDVPVIENLNITIPKGSLFTLLGASGCGKTT
                     LLRMIAGFNSIKDGEFYFDDTKINNMEPSKRNIGLVFQNYAIFPHLTVRDNVAFGLMQ
                     KKVPKEELIQQTNKYLELMQIAQYADRKPDKLSGGQQQRVTLACALAVNPSVLLMDEP
                     LSNLEAKLRLDMRQTIREIQHEVGITTVYVTHDQEEAMAISDQIAVMKDGVIQQIGRP
                     KELYHKPANEFVATFIGRTNIIPANLEKRSDGAYIVFSDGYALRMLALDQVEEQAIHV
                     SIRPEEFIKDESGDIEGTISDSVYLGLNTEYFIETGFASKIQVSEESTFEEDLQKDNR
                     IRLRINTQKLNIFSADGSQNLIKGVNHGT"
     gene            complement(62802..63803)
                     /locus_tag="ACL29Z_000304"
                     /pseudo
     CDS             complement(62802..63803)
                     /locus_tag="ACL29Z_000304"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003085230.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
     gene            complement(64140..64364)
                     /locus_tag="ACL29Z_000305"
                     /pseudo
     CDS             complement(64140..64364)
                     /locus_tag="ACL29Z_000305"
                     /inference="COORDINATES: protein motif:HMM:NF024242.4"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0043565 - sequence-specific DNA binding
                     [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
     gene            complement(64412..65188)
                     /locus_tag="ACL29Z_000306"
     CDS             complement(64412..65188)
                     /locus_tag="ACL29Z_000306"
                     /EC_number="1.97.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000406168.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA];
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA];
                     GO_process: GO:0043687 - post-translational protein
                     modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycyl-radical enzyme activating protein"
                     /protein_id="HGR0068677.1"
                     /translation="MEISKGIIFNIQHFSIHDGPGIRTTVFLKGCPLRCPWCSNPESQ
                     RMKPEKMKDAQREKFTLVGEEKTVEEIITEVLKDKEFYEESGGGLTLSGGEIFAQFEF
                     AKAILKSAKEHHIHTAIETTAFVDHEKFIDLIQYVDFIYTDLKHYNSIKHKKVTGVFN
                     QMIIKNIHYAFSQNKTIVLRIPVIPNFNNSLEDAEKFATLFNSLNIDQVQLLPFHQFG
                     ENKYRLLNRKYEMDGINALHPEDLIDYQKVFLNHHINCYF"
     gene            65310..66056
                     /locus_tag="ACL29Z_000307"
     CDS             65310..66056
                     /locus_tag="ACL29Z_000307"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000824973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR family DNA-binding transcription
                     regulator"
                     /protein_id="HGR0068678.1"
                     /translation="MKRLEQIIKLVSEYEKIDVNTLSEKLNVSKVTIRKDLDKLESKG
                     LLHREHGYAVLNSGDDLNVRLSINYEIKRKIVQEAVKLVSDNETIMIESGSTCALLAE
                     EICKQKRNVTIVTNSFFIANFVRAYDSCRIIVLGGEFQKDSQVTVGPLLKEMIQTFHV
                     HQAFVGTDGYDKEMGFTGKDLMRSEVVQYISAASDKVIVLTDSSKFDKRGTVRRFALS
                     QVYEVITDEKLSKQNIATLENAGIMVKVVS"
     gene            66069..67049
                     /locus_tag="ACL29Z_000308"
     CDS             66069..67049
                     /locus_tag="ACL29Z_000308"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001070834.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0030246 - carbohydrate binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sugar-binding transcriptional regulator"
                     /protein_id="HGR0068679.1"
                     /translation="MNQDRNKLLSKIAYLYYIENLNQSQIAAKLGIYRTSISRMLTEA
                     RNAGIVKIEIENFDTNMFKLENYVKEKYGLESLEIIPNEFDDNPTILSERISQVAAGV
                     LRNLIDDNMKIGFSWGKSLSNLVDLIHSKSVRNVHFYPLAGGPSHIHAKYHVNTLIYE
                     MSRKFHGECTFMNATIVQENKLLADGILQSRYFENLKNSWKDLDIAVVGIGDFSNKGK
                     HQWLDMLTEDDFKELTKVKTVGEICCRFFDSKGKEVYENLQERTIAISLEDLKNIPQS
                     LAVAYGDTKVSSILSVLRANLVNHLITDKNTILKVLEEDGDLTFREILGE"
     gene            67244..67564
                     /locus_tag="ACL29Z_000309"
     CDS             67244..67564
                     /locus_tag="ACL29Z_000309"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000402908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HGR0068680.1"
                     /translation="MEIIVPDQIIMGLILYAGDAKQHIYKALDYIKNGTCERCEEEIQ
                     LADAALLEAHNLQTKFLAQEASGTKTEITALFVHSQDHLMTSMTEINLIKEIISLRKE
                     LHKK"
     gene            67610..67918
                     /locus_tag="ACL29Z_000310"
     CDS             67610..67918
                     /locus_tag="ACL29Z_000310"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000238716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HGR0068681.1"
                     /translation="MVKIGLFCAAGFSTGMLVNNMKIAAQSSGVEAEIEAFSQSKLAD
                     YAPNIDVALLGPQVAYTLDKSKEICDKCDVPIAVIPMMDYGMLDGKKVLDLALSLISG
                     "
     gene            67935..69233
                     /locus_tag="ACL29Z_000311"
     CDS             67935..69233
                     /locus_tag="ACL29Z_000311"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000041357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0016773 - phosphotransferase activity,
                     alcohol group as acceptor [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HGR0068682.1"
                     /translation="MSKMDVQKIIAPMMKFVNMRGIIALKDGMLAILPLTVVGSLFLI
                     MGQLPFEGLNKSIASVFGANWTEPFMQVYSGTFAIMGLISCFSIAYSYAKNSGVEALP
                     AGVLSVSAFFILLRSSYIPKQGEAIGDAISKVWFGGQGIIGAIIIGLVVGSIYTFFIK
                     RKIVIKMPEQVPQAIAKQFEAMIPAFVIFLSSMIVYILAKSLTNGGTFIEMIYSAIQV
                     PLQGLTGSLYGAIGIAFFISFLWWFGVHGQSVVNGVVTALLLSNLDANKAMLASANLS
                     LENGAHIVTQQFLDSFLILSGSGITFGLVVAMLFAAKSKQYQALGKVAAFPAIFNVNE
                     PVVFGFPIVMNPVMFVPFILVPVLAAVIVYGAIATGFMQPFSGVTLPWSTPAILSGFL
                     VGGWQGVVTQLLVLVISTVVYFPFFKIQDRLAYQNEIKQS"
     gene            69384..71822
                     /locus_tag="ACL29Z_000312"
     CDS             69384..71822
                     /locus_tag="ACL29Z_000312"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000248319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycyl radical protein"
                     /protein_id="HGR0068683.1"
                     /translation="MVNTEVARTTIKTEYFGSLTERMNKYREDVLNKKPYIDAERAVL
                     ATRAYERYKEQPNVLKRAYMLKEILENMSIYIEEESMIAGNQASSNKDAPIFPEYTLE
                     FVLNELDLFEKRDGDVFYITEETKEQLRSIAPFWENNNLRARAGALLPEEVSVYMETG
                     FFGMEGKMNSGDAHLAVNYQKLLQFGLRGFEERARKAKVALDLTDPASIDKYHFYDSI
                     FIVIDAIKVYAKRFVALAKSLAENANPKRKKELLEIADICSRVPYEPATTFAEAIQSV
                     WFIQCILQIESNGHSLSYGRFDQYMYPYMKADLESGKETEDSIVERLTNLWIKTITIN
                     KVRSQSHTFSSAGSPLYQNVTIGGQTRDKKDAVNPLSYLVLKSVAQTHLPQPNLTVRY
                     HAGLDARFMNECIEVMKLGFGMPAFNNDEIIIPSFIAKGVLEDDAYDYSAIGCVETAV
                     PGKWGYRCTGMSYMNFPKVLLITMNDGIDPASGKRFAPSFGHFKDMKNFSELENAWDK
                     TLRYLTRMSVIVENSIDLSLEREVPDILCSALTDDCIGRGKHLKEGGAVYDYISGLQV
                     GIANLSDSLAAIKKLVFEEERISPSQLWHALETDYAGEEGKVIQEMLIHDAPKYGNDD
                     DYADKLVTAAYDIYVDEIAKYPNTRYGRGPIGGIRYSGTSSISANVGQGRGTLATPDG
                     RNAGTPLAEGCSPSHNMDQHGPTSVLKSVSKLPTDEIVGGVLLNQKVNPQTLAKEEDK
                     LKLIALLRTFFNRLHGYHIQYNVVSRETLIDAQKHPEKHRDLIVRVAGYSAFFNVLSK
                     ATQDDIIGRTEHSL"
     gene            71841..72509
                     /locus_tag="ACL29Z_000313"
     CDS             71841..72509
                     /locus_tag="ACL29Z_000313"
                     /EC_number="4.1.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000395441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016832 - aldehyde-lyase activity
                     [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-6-phosphate aldolase"
                     /protein_id="HGR0068684.1"
                     /translation="MEFMLDTLNLDEIKKWSEILPLAGVTSNPTIAKREGSINFFERI
                     KDVRELIGSTPSIHVQVISQDFEGILKDAHEIRRQAGDDIFIKVPVTPAGLRAIKVLK
                     KEGYHITATAIYTVIQGLLAIEVGADYLAPYYNRMENLNIDSNSVIRQLALAIDRQNS
                     PSKILAASFKNVAQVNNALAAGAHAVTAGADVFESAFAMPSIQKAVDDFSDDWFVTQN
                     SRSI"
     gene            72527..73615
                     /locus_tag="ACL29Z_000314"
     CDS             72527..73615
                     /locus_tag="ACL29Z_000314"
                     /EC_number="1.1.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001860765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_function: GO:0008888 - glycerol dehydrogenase (NAD+)
                     activity [Evidence IEA];
                     GO_function: GO:0030554 - adenyl nucleotide binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol dehydrogenase"
                     /protein_id="HGR0068685.1"
                     /translation="MRIFASPSRYIQGENALFENAKSILDLGNYPILLCDQLVYDIVG
                     KRFEDYLHRYGFHIVLALFNGEASDNEINRVVALAEKENCDSIIGLGGGKTIDSAKAI
                     ADLIEKPVIIAPTIASTDAPVSALSVIYTDEGAFDHYLFYSKNPDLVLVDTKVISQAP
                     KRLLASGIADGLATWVEARAVMQANGKTMLGQQQTLAGVAIAKKCEETLFADGLQAMA
                     ACEAKVVTPALENIVEANTLLSGLGFESGGLAAAHAIHNGFTALTGDIHHLTHGEKVA
                     YGTLVQLLLENRPKEELDKYIEFYKKIGMPTTLKEMHLDQVGYDDLIKVGKQATMEGE
                     TIHQMPFKISPSDVAQAIIAVDAYVNSK"
BASE COUNT        22309 a        13403 c        16113 g        21846 t
ORIGIN      
        1 aatagtccat gctgtggctg gattcttttc agcctactta tactcttcga aactctcttc
       61 aaaccacgtc agcttcacct tgccgtaggt atggttactg acttcgtcag ttctatccac
      121 aacctcaaaa cagtgttttg agctgacttc atcagttcta tccacaacct caaaacggtg
      181 ttttgagcaa cctgcggcta gtttcctagt ttgctctttg attttcattg agtattatta
      241 agacaatata aggagaaaga tgaaagaaaa aggattttag gagggggcgc aggcagccat
      301 gccaacggct cttggctatg tcagtatcgg cctggcctgt gggactatcg gtgcgcccta
      361 tgtgacacct gttgagatgg gcttgatgag tctctttgtt tatgctggga gtgcccagtt
      421 tgccatgttg gcactgattg tggttcaagc tcctgtggca gctattgcta tgacggtttt
      481 tctaatcaac ttgcgtctct ttttgttgag tttacacgca tcgacttatt tccgtcatac
      541 cagtctttgg tacaatatcg gtatgtctag tatcttgaca gatgagacct atggcgtttt
      601 gatgggtgaa ttggcccata cagacaaggt aaatcctatg tggatgcacg gaaacaatct
      661 taacagctat gtggcttggt ttgtggggac agtagtcgga acggctctgg gtggcctgct
      721 accaaatcca gaaatctttg gcttggattt tgccctggtt gggatgttta ttggtatttt
      781 tgcttcgcaa tttcagatta tgcaaagacg gattcctgtc cgcaatctgc tcattatcct
      841 agcagttgtt gcggtgtcct tctttttgct cttgacagtg gtgtctcagt cactagctgt
      901 tctgtttgcg acgctacttg gttgtagcat gggggtggtt ttagatggtc agtaagtatc
      961 ttttattagc agttattttc tctggcttgg tgacttggat tctccgtatg attcccttca
     1021 tcttagtcaa gtataagggc ttgcctgcaa tcgttgagcg ttttttgaag ttcttgcccg
     1081 tttccattat ctttgccttg attctttcaa gcgtagtgac aggtaaggtt gggagccttc
     1141 ctcaaattaa atggctagac ttcttagccg tctttccaac agcttgggta gcctttcgct
     1201 accgcaatct agtcggaaca gttctctttg gagtggtctt gattgccatc ttgcgtttgg
     1261 tcttttaaat tacccataaa aaaaacttat cacagagata gatatcatat aatggcgtaa
     1321 atgctctttt tctgttaaga ttataaggta ttctattttg gaggaaatga catgaaaaaa
     1381 atcgttaaat actcatctct tgcagccctt gctcttgttg ctgcaggtgt gcttgcggct
     1441 tgctcaggtg gtgctaagaa agaaggagaa gcagctagca agaaagaaat catcgttgca
     1501 accaatggat caccaaagcc atttatctat gaagaaaatg gcgaattgac tggttatgag
     1561 attgaagtcg ttcgcgctat ctttaaagat tctgacaagt atgatgtcaa gtttgaaaag
     1621 acagaatggt caggtgtctt tgctggtctt gacgctgatc gttacaatat ggctgtcaac
     1681 aatcttagct acactaaaga acgtgcggag aaatacctct atgccgcacc aattgcccaa
     1741 aatcctaatg tccttgtcgt gaagaaagat gactctagta tcaagtctct cgatgatatc
     1801 ggtggaaaat cgacggaagt cgttcaagcc actacatcag ctaagcagtt agaagcatac
     1861 aatgctgaac acacggacaa cccaactatc cttaactata ctaaggcaga cttccaacaa
     1921 atcatggtac gtttgagcga tggacaattt gactataaga tttttgataa aatcggtgtt
     1981 gaaacagtga tcaagaacca aggtttggac aacttgaaag ttatcgaact tccaagcgac
     2041 caacaaccgt acgtttaccc acttcttgct cagggtcaag atgagttgaa atcgtttgta
     2101 gacaaacgca tcaaagaact ttataaagat ggaactcttg aaaaattgtc taaacaattc
     2161 ttcggagaca cttatctacc ggcagaagct gatattaaat aatttcttga aatcatccat
     2221 tctgagtaag gtgggtggtt tctcagtttt tagggatata gttttaaact atatatctga
     2281 ctatctaata acaatttgtg aaatcaaaca aattgtgaga tactagtacg gtattatttt
     2341 taaggagaaa gaatcatgaa aatcaaaaaa tggcttggtc tagcagccct tgctacagtc
     2401 gcaggtttgg ctcttgcagc ttgcggaaac tcagaaaaga aagcagacaa tgcaacaact
     2461 atcaaaatcg caactgttaa ccgtagcggt tctgaagaaa aacgttggga caaaatccaa
     2521 gaattggtta aaaaagacgg aattaccttg gaatttacag agttcacaga ctactcacaa
     2581 ccaaacaaag caactgctga tggcgaagta gatttgaacg ctttccaaca ctataacttc
     2641 ttgaacaact ggaacaaaga aaacggaaaa gaccttgtag cgattggaga tacttacatc
     2701 tctccaatcc gcctttactc aggtttgaat ggaagtgcca acaagtacac taaagtagaa
     2761 gacatcccag caaacggaga aatcgctgta ccgaatgacg ctacaaacga aagccgtgcg
     2821 ctttacttgc ttcaatcagc tggcttgatt aaattgggtg tttctggaac tgctcttgca
     2881 acagttgcca acatcaaaga aaatccaaag aacttgaaaa tcactgaatt ggacgctagc
     2941 caaacagctc gttcattgtc atcagttgac gctgccgttg taaacaatac cttcgttaca
     3001 gaagcaaaat tggactacaa gaaagcactt ttcaaagaac aagctgatga aaactcaaaa
     3061 caatggtaca acatcattgt tgcgaaaaaa gattgggaaa catcacctaa ggctgatgct
     3121 atcaagaaag taatcgcagc ttaccacaca gatgacgtga aaaaagttat cgaagaaaca
     3181 tcagacggtt tggatcaacc agtttggtaa taagaaacag ggaggtggga gagagaattc
     3241 cacctcttgc ttttgtatag agcacggagt gtaaagaaga ttattcgttc atagaaaggt
     3301 agagagaata tggtttttcc tagcgaacaa gaacagattg aaaaatttga aaaggatcat
     3361 gtagtccaac attattttga ggttttgcgt accttgattt ctaagaaatc agtctttgcc
     3421 cagcaggttg gactcaagga agtcgcaaat tatctgggtg agattttcaa gcgtgttgga
     3481 gctgaagtgg agattgatga gagctataca gcgccctttg tcatggcaca tttcaagagt
     3541 tcgcgtccag atgccaagac cttgattttc tataaccact atgacactgt gccagcggat
     3601 ggggatcagg tctggacaga ggctcctttt acgctttcgg tccgcaatgg cttcatgtat
     3661 gggcgtgggg ttgatgacga caagggtcat atcacagctc gcttgagtgc tttgagaaaa
     3721 tatatgcagc accatgatga tttacctgtc aatatcagct ttatcatgga gggagcggag
     3781 gaatcggctt caacagacct agataagtat ttggaaaagc atgcagacaa actccgtggg
     3841 gcggatttgt tggtctggga acaagggacc aaaaatgcct tggaacagct ggaaatttct
     3901 ggtggcaata aggggattgt gacctttgat gtcaaggtaa aaagcgctga tgtggatatc
     3961 cactcgagtt atggtggtgt tgtggaatca gctccttggt atctcctcca agccttacag
     4021 tctcttcgtg ctgcggatgg ccgtatcttg gttgaaggct tgtacgaaga agtacaagag
     4081 cccaatgaac gagaaatggc cttgctagaa acttatggtc aacgaaaccc agaggaagtt
     4141 agtcggattt atggattgga gttgcctctc ttacaggagg agcggatggc ctttctaaaa
     4201 cgtttctttt tcgagccagc gcttaatatc gaaggaatcc agtctggtta tcaaggtcag
     4261 ggtgttaaga ctattttgcc tgcagaagcc agtgccaagc tagaggttcg tctggttccg
     4321 ggtctagaac cgcatgatgt tctggaaaaa attcggaaac agctagacaa aaatggcttt
     4381 gataaggtag aattatacta taccttggga gagatgagct atcgaagcga tatgagcgca
     4441 ccagccattc tcaatgtgat cgagttggcc aagaaattct atccacaggg cgtttcagtc
     4501 ttgccgacga cagcggggac aggacctatg catacggtct ttgatgccct agaggtgcca
     4561 atggttgcat tcggtctagg aaatgccaat agccgagacc acggtggaga tgaaaatgtg
     4621 cgaatcgctg attattatac ccatatcgaa ttagtagagg agctgattag aagctatgag
     4681 tagagatatt atcaagttag atcagatcga tgtgactttt caccaaaaga agagaaccat
     4741 cacagcggtt aaggatgtga ccattcacat ccaagaaggg gatatctacg gaatcgttgg
     4801 atattctgga gcagggaaat caacccttgt acgggtgatt aacctcttgc aaaaaccatc
     4861 tgcagggaaa attaccattg acgacgatgt gatttttgat ggtaaggtga ccttgacggc
     4921 agagcagttg cgtcgtaaac gtcaagatat cgggatgatt ttccagcatt ttaacctgat
     4981 gagccaaaag acagcagagg agaatgtagc ctttgccctt aaacactctg gactcagcaa
     5041 ggaagaaaag aaggctaaag tagctaagtt gttggacttg gttggtttgg cagatcgtgc
     5101 tgaaaactac ccttcacaac tatctggagg gcaaaaacag cgtgtggcaa ttgcgcgtgc
     5161 cttggccaat gatccaaaaa tcttgatttc agacgagtca acttctgccc ttgaccctaa
     5221 gacaaccaag cagattttgg ccttgttgca agatttgaac caaaaattag gattgacagt
     5281 tgtcttgatt acgcatgaaa tgcagattgt caaagacatt gccaaccgtg tggcggttat
     5341 gcaggatggg catttgattg aagagggaag tgtccttgaa atcttctcaa accctaaaca
     5401 acctttgact caagacttta tctcaacagc cacaggtatt gacgaagcca tggtcaaaat
     5461 cgagaagcaa gaaatcgtgg aacacttgtc tgaaaacagt ctcttggtgc aactcaagta
     5521 cgctggagct tcaacagacg agccactttt gaatgaattg tacaagcatt accaagtaat
     5581 ggctaatatt ctctatggga atatcgaaat tctcgatggt actcctgttg gagaattggt
     5641 ggtggtcttg tcaggtgaaa aagcagcgtt ggcaggtgcc caagaagcca ttcgtcaagc
     5701 aggtgtacaa ctaaaagtat tgaagggagg acagtaagat ggaatcattg attcaaacct
     5761 atttaccaaa tgtctataaa atgggttggg ctggtcaggc aggctgggga acggctatct
     5821 acttaactct ttatatgaca gttctttcct tcattatcgg aggcttcttg gggctagtgg
     5881 caggtctctt tctcgtcttg acagcgccag gtggtgtctt ggagaataaa gtcgtattct
     5941 ggattttaga caaaattacc tcaatttttc gtgcggttcc ctttatcatc ctcttggcaa
     6001 tcttgtcacc actttctcac ttgattgtta aaacaagtat cgggccaaat gcagcccttg
     6061 tcccactttc ttttgcagtc tttgccttct ttgcccgtca ggtgcaggtt gtcttggctg
     6121 aattggatgg cggtgtcatt gaggcggctc aagcgagcgg agcgactttc tgggacatcg
     6181 tgggtgttta cctatcagaa ggtcttccag atttgatccg tgtgacgact gtgaccttga
     6241 tttcccttgt tggggaaaca gctatggccg gtgcggttgg agctggtggt atcggtaacg
     6301 tagccatcgc ttatggattt aaccgctaca atcacgatgt gaccatcttg gcaaccatta
     6361 ttatcatttt gattatcttt gcaatccaat tcttgggaga tttcttgact aagaaattga
     6421 gccataaata aaaaagagcc gcgtggctct ttttaactga tcagattttc tgtgcaaatt
     6481 ttttactcaa ggcttgtcca atcaaggcac ccactagggc tccgatgaca atacttgcga
     6541 taaatagaag gacagttcca gggtttggag cgaccatgat acggtcgata tattcttggg
     6601 attttcctct tgccagaaga gtagccatat aggctttggg cgcaatccac ataagcaaga
     6661 ttggtcctgt tgtactaaag gcgaaaataa tgaaagaaag gaagttcttt gttttgtcct
     6721 tgtattttcc taaatgagct actccatctg ctaggaggcc acagataatt ccaggaagga
     6781 aggaaccagc accgtgttta gttcccaaga aaaagagggc aatgacaagg ccgatagtgg
     6841 taatggctcc aaagcgcgga acttttgcga ctaggatcat gtagacgcta ccgccgacaa
     6901 gggcagtaaa ggcaggcgca taaaacatgt ttccagtttg gtcaaagaga ttgcccaaaa
     6961 ggacaccaat ccccatgcag aggaagtaaa gaactgcaaa aagcagtgta gttaagatag
     7021 atttcttcat gaattgtctc ctgataattt tttcacaatt ctcattttac catggtttgg
     7081 tgggattgta aatggatact agaagttttt gaaaacgctt gaaatatgat ataatggttt
     7141 catagttatt tttaggggaa tatcatgggt agatttttag actttgtctt taatcgtttc
     7201 tttttaggga tgattgcgac agccttcttt tggctattaa ctttagcagg agggattatc
     7261 cttggtctag cgccggctag tgccaccttg atgagcttat atgcagaaca tggttatagc
     7321 tttcgggaat acagtttgaa ggaggcttgg tctctttaca agcaaaattt tatctcaagc
     7381 aacctgattt tctatagctt tttaggtgtg ggtctagttt tgacctatgg tttgtatctc
     7441 ttggtgcaat tacctcatca gaccattgtt catttgattg cgaccctttt gaatgtccta
     7501 gtagttgccc tgatcttttt ggcttataca gtatctttaa aattacaagt ttattttgcc
     7561 ttgtcctatc gaaatagtct caaattatcc ttgattggca tctttatgag tctagcagct
     7621 gtggctaagg ttctccttgg gactgtgcta cttgtagcaa ttggttatta tatgcctgcc
     7681 ctgctatttt ttgtaggaat tgggatgtgg catttcttta tcagtgatat gttggaacct
     7741 gtctatgaaa tcatccatga aaaattggcg acaaaataga atgaagcagt tttggctaca
     7801 tacgcttcta agaacctata gttcagtgat gatcattatc attgcgagtt ttgcaatctt
     7861 actctcttac gctgactggg attcacgtga aaaggaagcc cagagagtag cccagcgtgt
     7921 aactgctaga acagtgagtg aaattgaata ttaccataga gagtcaaccc agatagctca
     7981 ggctttagtt gaaaatcaag ctcgtatcga gggaatctat aaatacttta gccttagcat
     8041 gccagactat ttttactggc aattagagcg gaaagcttcg ccttatatat cagtctctct
     8101 gtatgaaaat gttgatgacc tctatgttcg aaatgatttt gtaactgggg tggccattgc
     8161 ttttcaagat tacaaggaag tctatgtttc tactaaagac aaacgtagtg gagaaaaaat
     8221 cagggctgag gatttcaaac cagcaggaaa tagttttgcc attccggtgt cagatccagt
     8281 gtcagatcaa gatttaggag tgatttacat ctccttggat cctgctgttt tataccatgc
     8341 cattgataat actagaggtc atactccgat ggcagtaaca gtgacctcac cttttgatac
     8401 ggagattttt catattggtg agacagttga tagggagagt gaaaattggc tagttggctt
     8461 aacttctcat ggatatcagg ttcaggtggc agttcctaaa aactttgttt tacaaggaac
     8521 agtgactagc tctgctttga ttgtgggttt gagccttctc tttattgtca ttctttatct
     8581 gactttgagg cagacttttg ctaattacca aaagcaggta gtggatttag tagaatccat
     8641 tcaagtcatt gctcaaggcg aagaggggcg tcggattgac atttccgaga aagatcagga
     8701 attactccta atcgcggaga cgaccaatga tatgttggat cgattggaaa agaatatcca
     8761 tgatatttac cagttagagc ttagtcaaaa agatgccaat atgcgagcct tgcaggcgca
     8821 aatcaatcct cattttatgt ataatacgct ggagttcttg cgcatgtatg cagttatgca
     8881 gagtcaagat gagttggcag atatcattta tgaattcagt agtctcttgc gtaacaatat
     8941 ttccgacgaa agagagaccc tcctcaaaca ggaattagaa ttttgccgta aatacagcta
     9001 tctctgcatg gttcgctatc ccaagtccat tgcctatggt ttcaagatag atccagagtt
     9061 agagaatatg aagattccca agtttacctt gcaaccgctg gtagaaaact atttcgcgca
     9121 tggtgttgac cacaggcgga cagataatgt gattagcatc aaggctctta aacaggatgg
     9181 ttttgtggaa attttggtgg tcgataatgg tagaggaatg tcggctgaaa agttggcaaa
     9241 tatccgagaa aaattaagtc agaaatattt tgaacaccaa gccagctaca gtgatcaaag
     9301 gcagtctatc gggattgtca atgtacacga gcgttttgtg ctctattttg gagaccgcta
     9361 tgccattact atagagtctg cagagcaagc cggtgttcag tatcgtatta caattcaaga
     9421 tgagtagaaa gggagaaaat gtataaagta ttattagtag atgatgagta catggtgaca
     9481 gaaggtctga agcgtttgat tccctttgat aagtgggata tggaggtcgt cgcaacagcc
     9541 agtcatgccg atgaagctct agaatatgtt caggaaaatc ctgtcgatgt catcatttcc
     9601 gatgtcaata tgccagacaa aacagggctt gatatgattc gggagatgaa agagttctta
     9661 ccagatgctg cctatatcct gctctcaggt taccaggagt ttgattatgt aaaaagagca
     9721 atgaacctta gtgtggtgga ctatttggtc aagcctgttg ataaggtaga gctgggaaat
     9781 ctgctggaga agattgcagg tcagctcggc gagagaggga agaaaagtca gactcttagt
     9841 caagaattag acgaggctgg atttgttagt tatttagggg ataaggagaa ttggtggata
     9901 ggtctatcca aggaaaaaca aggttctttc accattccct actatgtctt gggtcaagac
     9961 tggcagattt tcatttctga ccaaccccta gatggtttag tcgttacacc ttttgaagct
    10021 ccttatcaag aacactttga acgctggaag ctgaatgctg agaaaaccct cttttacggt
    10081 tctgtaaatc tgcagcagtc tgagagtctc tttgcctatt acgaaccgat ttatagggtt
    10141 atcattcagg gaaatctcaa tcaaatcgta gaagagttaa atcttttgga gaaggtagtt
    10201 cttgaaaata cgccgcgtgt tccgattact aaacagcttt ttattcagtt tgtcatggat
    10261 gttttccatt tatttgaaca tctcaaagct gatgacctga cagacatcgt caaaaccatt
    10321 catgctattc aatccttcga tgaattggtt ccttatatca aggaaactct gagcagcttt
    10381 ttcggtcaat accgtatgaa tgaaaatgtg gtcagtgtgc tggaagtcat tggtcgtgat
    10441 taccaaaaag agctttccct caaggatatc agtaaggctc tctttatcaa tcctgtctat
    10501 ctagggcagt tgattaagcg tgaaaccgat tcgacttttg cagagttact aaacaaacaa
    10561 cgtattaagg ctgcccaaca acttttgctt tcaactagtg acagcatcga agatatttgt
    10621 tatgctgttg gttacagtaa ccttggatat ttctataaag ttttccgaaa attgtgcgga
    10681 aaatcgccaa aagcctaccg aaaacaggta gaaactatac tataaaattt gtattccttt
    10741 acaaaaggtg ctataatatt atcaggaggt tctatcatga aaaagaaacc aatttatcta
    10801 tgggtcttgc taatcttgtc tgcccttatt tcagttccgt ctctgtttgg aattgtgagt
    10861 cccttgccta gtaaagaagc ccttcgtgct gctcagaaac aagttgcagg ggtcaatgct
    10921 cagcaattag aagaccagct taattatacc tatagagtag cagaagcatc tcattctatt
    10981 tttaatgttg ctttgattgt gctatctact attttagtgg tcgtagcgat tgtcttcctt
    11041 gttcgtaaaa atttgcaata tgcaaattat acttacgttg gctatgtttt gttagctatt
    11101 attggttcga tttatggcta tgttggttta caggacgctg tgcagttggt tcaagatgag
    11161 agcatgcgtt tgacagtgag tattggttca aaagctgtta gcattttcta tatcgtcatc
    11221 aatgttctct tcctagccct tgtcttctat aagatgtggc gacaacagaa agccttggca
    11281 gaggaagagg aaacagaaga gcttgcctaa gtattgacaa aaaagaacta tcaagataca
    11341 atcttggtag ttgttttttg attatagata aaatcatgga ggtacatatg aagacaattt
    11401 ctttagttta tattagtttg agtggcaaca ctgaaagttt tgtgacgcgc ttgaaagact
    11461 atctcttgtc ccagtacaaa aggattgagg ttcaaaagat tcatatcaag gatttggtca
    11521 aggaaggcaa aaatttctat gaaatggacc atccctatgt cgcttttttg ccgacctatc
    11581 tcgaaggtgg gaatggcgtg gataacggag atgttgagat tttgacgaca ccggtgggag
    11641 attttattgc ctatggtaac aatgctagta agtgttttgg tgtggttggg tcaggaaatc
    11701 gtaactttaa taaccaatac tgcctaacag ccaagcaata cagtcaacgc tttggcttcc
    11761 ctgtattggc tgactttgaa atgcgaggca tgctggaaga tatcaaacat gtcgcagcta
    11821 ttatcgcaga tttgtatgag ttggaaaagg agaattaata ctcaatgaaa atcaaagagc
    11881 aaactaggaa gctagtcgca ggttgctcaa agcacagctt tgaggttgca gatagagctg
    11941 acgtggtttg aagagattct cgaatagtat aaagttctta taagaggtgg ttgaagttgt
    12001 tcaactgttt tttgagtata aacagtcttt aagaacgtaa aaaagcataa gttcaggtct
    12061 tcaaaacctt gttcttatgc tttttatcat agaaatattt gctgaatttt ctcttgaaat
    12121 gaaaccttat cttcatctcg cgcttgtccc ttaccctgct tttccgattg cgagtgcgta
    12181 gataaagaag atggcgaagc caaagaggaa aatcaatccc gcaatggcaa ggtgtttgag
    12241 ccaagaagga agatttttgt tttcacgcgt taccaaggcg taattcaaaa gagcaaagaa
    12301 aggtgttgtc aggaaagatc caatcatggc aaagcggagc atggttgaaa cctgaccagc
    12361 gaagaacttg ataatgacga taccgatgat agcagtgatg gtcatccaga tgttcaaaga
    12421 tttacgattg tcctcttttt gactgattag cagtcggaga gattcctgat taacgcgaga
    12481 atagccatcg ataacagtta taactgttcc aaagatacag aggaaggcaa taaaggtaat
    12541 caagtaacgg gaccattcgc caagaacaga ggcatacatg cccacgaatt gagagatgta
    12601 tttggctgaa gcagcttcaa ccgcctgccc tgtaggatac tgaatcagtg ctcccagtgc
    12661 cacaaagaag acggctagga tagctgttcc aatataacca gtgttaaagt caaacagagc
    12721 gtcttctgtg ttaaagttga cggtctttct cttttcagct gaccaaagtg aattgatggc
    12781 tgaaatttca ataggagccg gcatccatcc taggagggag acgatgaagg gcagagctgc
    12841 catttgccaa ggtgtcttct cgacaaaatc agaactgtat tctggatgct tgaccgctgc
    12901 tatgataact gccagaacag tcgcaatggt taaggcagac ataatccatt tgaccatgcc
    12961 gtctaaaagt ttgtagcctc caaagagtag catagcccaa atgattgcaa cgagaatgag
    13021 ggaccactga gtaatgctaa gtccaatcat tgggaaggca ctggcgatga tagctgagca
    13081 cagaatggca acaccagccg tgttgaccat agccgaaaag acattgagaa taaagaaaat
    13141 ccagagatag agttttcctt tttcggcata accttcaacc aaagtctttc cagtatcagc
    13201 tgtgtattca gcaccaaaac ggaaaaatgg atatttaaag acattggcta agatgaccaa
    13261 gagaagtaga gaccaaccgt aagaaccgcc agcttgagtt gaggatacaa tgtgggaacc
    13321 tccaacagcg gcagttgcca ttaggattcc aggtcccatt gcttttagct tgcttgccca
    13381 ggttgattga tttaaggaaa tagcttgcga catgataaat actccttttt gaattttcag
    13441 aataatctgt atatgcaatc tatattctac aaaaaatttt ggaaaaatgc aagaatattt
    13501 tgaaaaaaga tagaaaattt acaaagaaaa tctgaaataa ctgttatgat atagcagatt
    13561 gaaactagaa tagtacactt ttgcttctaa aacattgtta gaaatcgatt tgactgtcct
    13621 gattgattta tcctgttctt atttcatttc actatagtaa ggtgcagcag gataaagcaa
    13681 aaccgagaag tttctttctc ggttttgctt attatgaggt tcctattttc tatgctccaa
    13741 gagttgattg atgtgatcta cttttttagc ctctctttta tagagaatag cccagatgat
    13801 gagatagaca atcgcaaact cgataatgag ctggaggtag aaaatccagt ggaaggggaa
    13861 ccaaccagca agagttgcta gtgggacaaa gccagccagc ataaggaaga aatgagtcag
    13921 agtggcacga agcatgctcc agtcacggct gaataagcgg ttgccaaagt tgaagagcat
    13981 accgatggct gcccagataa gtgtgcagta gagcaagacc agggcaccgt gaacctgatg
    14041 ctgatccatc acttggccga tgagagagta gggatttagt ggtgcgtagg tatttggtgc
    14101 ataaatgagt gaaaagagga tggagaggat gaggccgata agaacaccgg cagctgcatc
    14161 gtgaaatact tgttttttca tagttctaat ttctccttga tggtttttag ataacggcgt
    14221 gaagagtagg tgaagctttc gtttttcaag aaaatttcta ccagaccgtt tggcgtgagc
    14281 ttgaggtgag agatggaatc gatattgatg atttctgatt gggaaatttg gataaaattg
    14341 gttggcaaga gtttaagaac ctgatagagt cgcaaatcaa tgctgtaggt ctgactcgcg
    14401 gtttctgcta gaaccttccg attctcgata tagaagcgct gaatcttgcc aatctcaact
    14461 agatagacct gatcatcgat ttttcctttg attttttctc tttggtccag attttctgcg
    14521 aactcgatga ctttctggac tttttcggtt tcttgaggtg cttggacaat cagcttttcc
    14581 tcctcgtaag tctcactaat ctgtagttct actttcataa atttctctcc ttgtttttca
    14641 tacaaaatta atctcacttc ttgtacacct ttattaatac tcttcaaaaa tctcttcaaa
    14701 ccacgtcagc gtcgtcttgc cgtaggatag ttgttgactt tgtcagtttt atctacaacc
    14761 tcaaaacagt gttttgagct gtctgcgtct agctttctag tttgctcttt gatttttatt
    14821 gagtatacca ctattttact ccctctggca aggtactttg tctatgtgga gggattgggc
    14881 tcctatgtgg tggagctttt ctgttctttc tgaaatatgg tataatagca ctaattaatt
    14941 tctaggaaaa tagatacaga aaggggctga aagatgtctc atattattga attgccagag
    15001 atgctggcaa accaaatcgc ggctggagag gtcattgaac gtcctgccag tgtggtcaaa
    15061 gagttggtag aaaatgccat tgacgcgggc tctagtcaga ttatcattga gattgaggaa
    15121 gctggtctca agaaggttca aatcacggat aacggtcatg gaattgccca cgatgaggtg
    15181 gagttggccc tgcgtcgcca tgcgaccagt aagataaaaa atcaagcaga tctctttcgg
    15241 attcggacgc ttggttttcg tggtgaagcc ttgccttcta ttgcgtctgt tagtgtcttg
    15301 actctgttaa cggcggtgga tggtgctagt catggaacca agttagtcgc gcgtgggggt
    15361 gaagttgagg aagtcatccc agcgactagt cctgtgggaa ccaaggtttg tgtggaggat
    15421 ctctttttca acacgcctgc ccgtctcaag tatatgaaga gccagcaagc ggagttgtct
    15481 catatcattg atattgtcaa ccgtctgggc ttggcccatc ctgagatttc ttttagcttg
    15541 attagtgatg gcaaggaaat gacgcggaca gcagggactg gtcaactgcg ccaagcaatc
    15601 gcaggaattt acggtttggt cagtgccaag aagatgattg aaattgagaa ctctgaccta
    15661 gatttcgaaa tttcaggttt tgtgtccttg cctgagttga ctcgggctaa ccgcaattat
    15721 atcagcctct tcatcaatgg ccgttatatt aagaacttcc tgctcaatcg tgctattttg
    15781 gatggttttg gaagcaagct tatggttgga cgttttccac tggctgtcat tcacatccat
    15841 atcgaccctt atctagcgga tgtcaatgtg catccaacta agcaagaggt gcggatttcc
    15901 aaggaaaaag aactgatgac tctggtttca gaagctattg caaatagtct caaggaacaa
    15961 accttgattc cagatgcctt ggaaaatctt gccaaatcga ccgtgcgcaa tcgtgagaag
    16021 gtggagcaaa ctattctccc actcaaagaa aatacgctct actatgagaa aactgagccg
    16081 tcaagaccta gtcaaactga agtagctgat tatcaggtag aattgactga tgaagggcag
    16141 gatttgaccc tgtttgccaa ggaaaccttg gaccgattga ccaagccagc aaaactgcat
    16201 tttgcagaga gaaagcctgc taactacgac cagctagacc atccagagtt agatcttgct
    16261 agcatcgata aggcttatga caaactggag cgagaagaag catccagctt cccagagttg
    16321 gagtttttcg gacaaatgca cgggacttat ctctttgccc aagggcgaga tggactttac
    16381 atcatagatc agcacgctgc tcaggaacgg gtcaagtacg aggagtaccg tgaaagcatt
    16441 ggcaatgttg accagagcca gcagcaactc ctagtgccct atatctttga atttcctgcg
    16501 gatgatgccc tgcgtctcaa ggaaagaatg cctctcttag aggaagtggg cgtctttcta
    16561 gcagagtacg gagaaaatca atttattcta cgtgaacatc ctatttggat ggcagaagaa
    16621 gagattgaat caggcatcta tgagatgtgc gacatgctcc ttttgaccaa ggaagtttct
    16681 atcaagaaat accgagcaga gctggctatc atgatgtctt gcaagcgatc tatcaaggcc
    16741 aatcatcgta ttgatgatca ttcagctaga caactcctct atcagctttc tcaatgtgac
    16801 aatccctata actgtcctca cggacgtcct gttttggtgc attttaccaa gtcggatatg
    16861 gaaaagatgt tccgacgtat tcaggaaaat cacaccagtc tccgtgagtt ggggaaatat
    16921 taaaagtata aaaaagtctg ggaaaaattt tcaaaatcag aaaaacgcat aaaatcaggt
    16981 gttcaaaaac cttgatttta tgcgttttat catagaaata tttacttcat tttttcctaa
    17041 ttcttttcga aactcttttt aaaccacgtc agttttatca gtaatctcaa aacagtgttt
    17101 tgagctaatt ttgccagttt tgtctgtaac atcgaagttg tgttttacca ctctgcgact
    17161 ggtttcctag tttgctctat gattttcaca gagtattaaa ttgcgatttt gccaagtttc
    17221 tttattcgtc taaaagtaga gtctgttcta tgcgtctaat gtacgaatta ggttaaccat
    17281 ttcaatagct ccttgtgcac actcagaacc cttatttcct gctttagtac cagctcgttc
    17341 tatggcttgt tcaattgtat ctgtcgttaa cacaccaaac ataacaggaa tttcgctatt
    17401 taaactgatt tgggcgattc ccttagatac ctcgctacat acataatcat aatgacttgt
    17461 attccctcta atgacagctc ccaagcagat aattgcatca tattttttac tttttgccat
    17521 ttttgatgca atcagtggta tttcaaaagc tcctggaacc caggctacct cgatatcttt
    17581 ctcgtttaca ttctctcttt tgagattatc tagtgctcca gataataatt ttgaagttat
    17641 aaattcatta aatctcgcta caacaatacc tattttaata ttgtttgcta ctaaattacc
    17701 ttcataagtg ttcatttatt tttcctccat atttaaaatg tgacccattc gatttttctt
    17761 tgtttctaaa taaaaactat cgtaaggatt ggcttctatt tcgattgata ttctactgga
    17821 aatggtaatt ccatattttt ctaactgttc aaccttgtca ggattatttg tcagtaaatg
    17881 aagtgactga agtcccagat ctttaagcat ttgtgctcca atatgatatt ctcttaaatc
    17941 accttcaaag cctaatgcaa gattggcatc aagcgtatcc atgccttgat cttgtaaatg
    18001 ataggctttt aatttattga taagtccaat tcctcgtccc tcctgtcgca agtaaagtaa
    18061 gacacccgaa ccattctcaa caatcatttt catagcttta tcgaattgct gtccacaatc
    18121 gcaacgtaag gagcctaaaa catcccctgt taaacattcg gagtggaccc gacataatac
    18181 attggcttca tcctctatgt ttcccataat aagagcaaga tgatgttccc catttagttt
    18241 atctatatag ctaattgctt tgaaattacc gtatctagta ggcatattga cagttgaaac
    18301 tcgttctacc agctgatcat atacttttct atattcttgt aattctttga tggtaattag
    18361 tggaatgttg tgtttcttcg agaactgaat taaatcatct gttctcatca ttttgccatc
    18421 atgattcatt atttcacaac ataggccaca ctcttttagt ccagctaatt ttaataaatc
    18481 aacagttgct tctgtgtgtc catttctttc tagaacacca cctttttttg caattaaagg
    18541 aaacatgtgt cctggcctgc gaaaatcaga gggtgttata tcttcagcta cacacatacg
    18601 tgcggtcagt cctctttcct cggcagaaat acctgtggtc gtttctttat aatcaattga
    18661 aactgtaaaa gcagtcttat gattatctgt attgttttca accataggtg aaagcattaa
    18721 ttgattagct aaactttcgc tcataggcat acaaattaat cctttggcat aagtagccat
    18781 aaaattaaca ttttctgttg tagctgcttg tgcagaacaa attaagtctc cttcattttc
    18841 tctatccttg tcgtctataa caagaacaag tcgtcccttc tgcaatgctt ctaatgcttc
    18901 ttgtattttt cgatattcca ttgactgatt atcctttctg ctaaaatcca ttttgatata
    18961 atagttcctt agatatttct gattttggag agttatccat cagtttttgc acatatttac
    19021 ctaagatatc attttcaaga tttactgtac tcccgacttg tttactctta agaatggttt
    19081 gtttcaaggt atgagggata acagatactg aaaagtttac tttggagact ttagcgacag
    19141 tcagactaat gccgtcaatt gtaatagatc ctttttcaac tattaaatct aaaatttctt
    19201 tttgtgtgtt gatttgatac catacagcat tatcatcttt ttttattgac gagatttttc
    19261 ctgtaccatc aatgtgtcct gtaacgacgt gacccccaag tcgaccgttg atagataagg
    19321 ctctttctag attcacctca cttccatgtt ttaatagagt aagagctgtt cgactccatg
    19381 tttcattcat tacatcaact gtaaaggatt gatgattgaa atgagtaact gtaagacaga
    19441 taccatttac tgctatacta tcgcctaaat ggatatccgt taatattttt gaggctttaa
    19501 ttgatagttt acaattacga gagtctttct gtattctttc aacttttccg atttcttcaa
    19561 ttattcctgt gaacatggat aaatcacttc actttctatg agatagtcat ttcctatttg
    19621 agaaaaagca taaggtttca atctaatagc gtcatttggc aaagaaatgc cttcacctcc
    19681 gacaggaaac ttggcactgc ctccaaaaat ttttggtgca atatatattt tcagctcatc
    19741 aacaatttgt tgttccaaag cactccaatt cattagactg cccccttcta gaactaggct
    19801 atcaatctgc atgtttccta gatgttgcat taaactcgat aagtctatat gattgccttt
    19861 tttctttatg gaaagtattt cacagccatg attttgatat agcttcattt tatttttgtc
    19921 ttcagaggaa gtggcaatgt aagttttaat atcatttgct gtttttacga ttttagaggt
    19981 aagaggagtt cgtaaatgtg tatcgcatat gatacggata ggatttttcc cttcctccaa
    20041 tctacatgtc agcaaaggat cgtcttgaat aacagtattg actcccacca taattgcact
    20101 aacatagtgt cgtaactgat gcacatgctt tcttgcttct tcttcagtaa tccatttgga
    20161 ttgatttgtt ttagtggcta tttttccatc cattgacatt gcatatttca taaaaacata
    20221 gggtacatgc tgggtaatat actttctaaa actttttatt aagttaagac actcattttc
    20281 taaaattcca acagtaactt gaagattatt ttcctcaagt atctttactc cttttccaga
    20341 tacaatagga ttacagtcta ggcttccaat gactactctt gtaataccac tatcgattat
    20401 agcatctata cagggaggtg ttttcccgaa gtgacaacag ggttcaagtg ttacataaag
    20461 cgtcgctccg acaggggatt ttctacagtt tttaagagca tttctctcag catgtgggcc
    20521 accaaaaaac tcatgataac cttgtccgat gatgtgatta tcttttacaa taactgcgcc
    20581 gaccatagga ttgggattga cgtaaccagc ccctttttgt gccagtttta ttgctaattt
    20641 catatatttt gaatcgctca tctcactacc tccaaaaaaa tatgccttga ataggggact
    20701 actcaaggca tacaaaagaa aacttatgcg attaacaaaa atgctctgaa atgacaagta
    20761 atcatttcag agcacgcaaa aagcacaaat atacttttat cttctttcat ccagactata
    20821 ctgtcggctt tggaatttca ccaaatcatg cctttcggct cgtgggctat accaccggta
    20881 gggaatttca ccctgccctg aagatagtta ttcaattaca gatgattata gtacttaatt
    20941 ttgaatatgt caacagataa ataccgattg tttttgatat actgtatttg tgataatcga
    21001 ttctcgctcc tcggataaag aaaatatgat atactagata aacgaaataa gagagaagga
    21061 atactatgta cgcatattta aaaggaatca ttaccaaaat tactgccaaa tacattgttc
    21121 ttgaaaccaa tggtattggt tatatcctgc atgtggccaa tccttatgcc tattcaggtc
    21181 aggttaatca ggaggctcag atttatgtgc atcaggttgt gcgtgaggac gcccatttgc
    21241 tttatggatt tcgctcagag gatgagaaaa agctctttct tagtctgatt tcggtctctg
    21301 ggattggtcc tgtatcagct cttgctatta tcgctgctga tgacaatgct ggcttggttc
    21361 aagccattga aaccaagaac atcacctact tgaccaagtt ccctaaaatt ggcaagaaaa
    21421 cagcccagca gatggtgctg gacttggaag gcaaggtagt agttgcagga gatggccttc
    21481 ctgccaaggt cgcagtgcaa gcaagtgctg aaaaccaaga attggaagaa gctatggaag
    21541 ccatgttggc tctgggctac aaggcaacag agctcaagaa aatcaagaaa ttctttgaag
    21601 gaacgacaga tacagctgag aactatatca agtcggccct taaaatgttg gtcaaatagg
    21661 agcagagaat gacaaaacgt tgttcgtggg tcaagatgac caacccactc tacatcgcct
    21721 atcatgatga ggagtggggc cagcccctcc atgatgacca agcgttgttt gagttgttgt
    21781 gtatggaaac ctatcaggca ggcctgtctt gggaaacggt actcaacaaa cgccaagctt
    21841 tccgagaagc ctttcatagc tatcaaattc actcagtcgc agagatgact gacactgaat
    21901 tggaagccat gctggagaat ccagctatca ttcgaaatag agccaagctt tttgctacac
    21961 gcgctaacgc ccaagtcttt ctacagttac aggcagagta cggctctttt gatgcctatc
    22021 tttggtcttt tgttgagggg aaaactgtcg ttaacgatgt tcctgattat cgccaagcgc
    22081 cagctaaaac acccttatct gagaaattag ccaaagatct caaaaaacga ggcttcaagt
    22141 tcacaggccc agtcgccgta ttgtcttttc tacaggctgc agggctagtt gatgaccacg
    22201 agaatgattg tgagtggaaa ggtcttaaat gatgtctaac aaaaataagg gaattctgat
    22261 ttttgcgatt ctctatacag tcctctttgt gtttgatggc gttaaattgc tggcttcttt
    22321 aatgccatct gtcattgcaa attatcttgt ttatgtagtt ttagctttat atggctcctt
    22381 cttgttcaag gatagattga tccaacaatg gaaggagatt agaaagacta aaagaaaatt
    22441 cttctttggc gtcttaacag gatggctctt tctcattctg atgactgttg tctttgaatt
    22501 tgtatcagag atgttgaagc agtttgtgag actagatgga caaggtctaa atcagtctaa
    22561 tattcaaagt acctttcaag aacaaccact actgatagct gtttttgctt gtgtcattgg
    22621 acctctggta gaagaattat ttttccgtca ggtcttattg cattacttgc aggaacggtt
    22681 gccaggttta ctaagcatta ttatggtagg acttgttttt gctctgactc atatgcacag
    22741 tttggcccta tcagagtgga ttggtgcagt tggttactta ggtggaggcc ttgccttttc
    22801 tattatttat gtgaaagaaa aagagaatat ctactatccc ctacttgttc acatgttaag
    22861 caacagcctc tccttaatca ttttagctat cagtatagta aaatgaaata agaacaggac
    22921 aaatcaatca ggacagtcaa atcgatttct aacaatgttt tagaagtaga ggtgtactat
    22981 tctagtttca atacactgta acatgtgatg aaaatgccag taatgatacc gagaaaaaag
    23041 ctgagaaact tttcccagct ttatttgtta tagtcaaagc gaatgacttg ttcctgtgca
    23101 tctacatgag catggacccc aaagggtaca attgctcttg gagttgcgtg gccgacattc
    23161 agattataga caatcgggat attgttgtca atgatatcca atagtgcctc tttatagtcg
    23221 tcatggaaag tttcatccat aggttttccg accaagagtc cattgatgac cgcgaatatg
    23281 ccagtgtcct ttaaagttag caacatcttt ttgaagtctt ctggcttagg ctcttcttcg
    23341 cttgtttcga gcaagaggat tttcccttcc cagtctgaca agtcagggaa aagtttgtat
    23401 ttttggcaga gttccgtgct atctgcgtat cgagagttgt caaagatatc gtagagggat
    23461 tcgaggcaac caccgaggat tttcccctcg aactgagcac ttccttgcaa caagtcaaaa
    23521 cctgtatttg tatgactgac acgaggtgtt cccagggccg tgggactaaa atcagttcgt
    23581 tcctcatacc aaacgtcact agggcggatt tctgaaattc ttcccgtctc aatcaattct
    23641 ttaaagtagt gaaggctata ggctagcatt tctttgtcta attcacaaat gtctgctaaa
    23701 aaggattgac cataaaaagt cttgattcct aatttatgca acatgaggtg gttcatggtt
    23761 gtatccgaga agccaagaaa aattttttgc ttgataacct tttggagttg gtcattttca
    23821 aaaagataag gtagcaagcg ataggtatcg tctccaccga tggcacatag gatcatgtcg
    23881 atgctatcat cagaaaaggc atgaatcaaa tcctctgcac gagcttcagg atggtccttg
    23941 ataaagtcta atccttttaa cgaatggggc aaaaagatgg gattgagtcc cagatccttg
    24001 agacgttgga tacccaagtc cacttcgtgt ttgacaaaat cctctccgat aatgccacta
    24061 gataaactaa caataccaat agtagaaacc atatctcatc ctcctagaaa tagattgagc
    24121 ctattttatc acaaaatata agagaaagct atgtgggatt tcagaagaat acttttaata
    24181 ctcttcgaaa atctcttcaa accacgtcag ttttatctgc aacctcaaag ctgtgctttg
    24241 agcaacctgc agctagcttc ctagtttgct ctttgacttt cattgagtat aactcaaaaa
    24301 agtaagtgaa aaagcaaccg cacctgcagt tgcttttatc gttttcttat tcttgatagc
    24361 gtgttggtcc tgcacttgca ctacggatat tcaagcgttt cttgagatag aagcgaaggg
    24421 ctaggagggc tgctccaata atagctagtg gcaatggatc cagtactggg ttaaggctag
    24481 ctggtaggaa gcttgttgca aagaagacaa gcaaccaaag gaacatagaa gctaggataa
    24541 ctagtacaga tttccagaaa ggtggacgtt gactgcgatc catatctggt ccatagtatt
    24601 ggtaaacaaa gtagtacatc aagtagaagg caaatccacc aaccagtcca actaatagaa
    24661 gagtaatcaa tccatagccg aaagcttgat ctgccgcaaa gaaggttgtg agggcgctga
    24721 caagggcaaa gaggctagtg atgaaaagag ctgagtccat aatcatcagt tttgggtcat
    24781 cattttcttt tggatgctct ttttcgtact gctctttgac agtgaagcta tgagcccaat
    24841 gagttggtgc gccgtatagg gaacgggcag ttgtaccttt agattgctcc tcaaggattt
    24901 ggggaatgac ttcctcaaaa atagtctgga tttcagcgtc tgttttccca tctttgatga
    24961 attgttgggt agcaatgtgg acaaactctt ggtttttctt agttaatttt tgtagatcaa
    25021 tttgagacat aggaactcct cttagaacca ttttttatgg atgagataga gagtgagcga
    25081 gacactcata gcaaaggcga taaagacgat taaccagaag gcatttggct ctccgtttag
    25141 ggggatttca ttatccttaa agttcatccc gtaggcagaa aagaccatgg ttgggatgga
    25201 catgacgatg gtcacaaggg ccaaggtttt catgatgttg ttctggttgt tagaaatgat
    25261 agaggcaaag gtctctgtca tagaatgcaa gacgtttcca taaatatctg ccatctcgat
    25321 ggcctgttgg gtttcaatca gggtgtcttc aagcaggtct tcgtcctcaa ggtatttctt
    25381 gatattgctg gttgaactgg tcaatttctt aatcacgcgc tcatttgttt tgagggaggc
    25441 cttgaaatag acgatagttt tttccaattc catgagctca atcaattctt cattacgagt
    25501 tgattgatgc agttgacttt cgatttgttc actcttgcgg tcgattgaac gaagggctgt
    25561 taggtaaagc tctgcattgc gataaagaat ttgaaagata aaacgtgaac gcatgaaggt
    25621 atagaaatta cgcaatcgac ggttgataaa gacatcaagg acaggtagtg gttccaaaca
    25681 cgtagtgata atggtttcct cagtgatgat aataccaagc gggatggtta cgtagtaggt
    25741 gcggttattt ctttcctccg tgaccggcac gtctacgata atcagggtat actcgtcttc
    25801 aatggtaata cgagacattt cttccgcatc gagcggtgct cgaaggtcgg caatatcaat
    25861 atcgaaggtg ttggcgattt cgagtgattc attttgagtc ggattgacga gattgatcca
    25921 agtacccggt tcaagcgtat cgatctcttt aaattcagtt gttgtagaga gaaaaacttg
    25981 tttcatatcc cttatccttt ctcatttttc agattttttc acactgtact attatactac
    26041 aaaatcggcc ttttgggtaa tagaatctca ctttttttgg tataatggta agcaataatg
    26101 gactagaaag aacaaagatg caagataaaa ttgtcattca tggggcgcgt gcccataatt
    26161 taaaaaatat tgatgtggag attccgcgag acaagttggt tgtcgtgact ggcttgtcag
    26221 gttcagggaa gtccagtctg gcttttgata ccctctatgc ggagggacaa cgtcgctatg
    26281 tagagagttt gtccgcctac gctcgtcagt tcttgggaaa tatggaaaaa ccagatgtag
    26341 atgccattga tggtctcagc ccagctattt ccatcgacca gaaaacgact agtaaaaatc
    26401 ctcgctcgac ggtgggaacg acgactgaaa tcaatgacta tctgcgtctc ctctacgcac
    26461 gtgtggggac gccttactgt atcaacggac atggagctat caatgcttct tctgtggagc
    26521 aaatcgttga taaggttttg gagttacctg aacgccagcg cttgcagatc ttggctcctg
    26581 tcatccgcaa gaaaaaaggc caacataaga gtgttatcga gaaggttcag aaagacgggt
    26641 atgttcgtgt tcgtgtggat ggggaagtct atgatgtgac cgaagtgcca gagttgtcta
    26701 agagcaagca acacaatatc gatgtcgtgg ttgaccgtat tgttatcaag gagggcattc
    26761 gtagccgtct ctttgattcc attgaagctg cccttcgtat cgcagaaggt tatgtgatta
    26821 tcgacaccat ggacgactct gagttgttgt tctctgagca ttatgcctgt ccagtttgtg
    26881 gatttactgt cccagagtta gaacctcgtc tcttctcttt caatgctccc tttggctctt
    26941 gtagtgagtg tgacggcttg gggattaagc tggaggtgga tactgatttg gtagtgccag
    27001 atgccagcaa aaccttacat gagggagcgc tggcaccttg gaatcctatc tcatccaact
    27061 actatccaaa catgttagag caggccatga aagtctttgg agtggctatg gataagcctt
    27121 ttgaggacct gtcagaagaa gataagaact tgattctcta cggctcagat ggtaaggaat
    27181 tccatttcca ttatgaaaat gaatttggtg gtgtgcgcga tatcgacatt ccgtttgagg
    27241 gagttatcaa taatatcaaa cgtcgttacc atgaaaccaa tagcgattac actcgcactc
    27301 agatgcgtct ctacatgaat gagctgacct gcggaacctg tcaaggctat cgtctcaatg
    27361 accaggcctt gtctgtccgt gtgggcggcc agcaagggcc acatattgga gaaatctcag
    27421 acctgtctat cgctgaccac ttggacttgg tgagccagtt aactttgtct gaaaatgaag
    27481 ccatcattgc tcgtcccatt ctcaaggaaa tcaaggatcg tttgaccttc cttaataatg
    27541 tgggtcttaa ctatctaacc ctgtcacgtt cagcaggaac cctttcaggt ggggaaagtc
    27601 agcgcattcg tttggcaacc cagattggtt ccaacctatc aggtgtcctc tatatcctag
    27661 acgagccgtc aatcggtctt caccagaggg acaatgaccg cctgattgcc agtctgaaaa
    27721 agatgcgtga cttgggcaat actcttatcg tggtggaaca cgacgaagat accatgcgtg
    27781 aagctgatta tctgattgac gttggtcctg gtgccggtgt ttttggtggt gagattgttg
    27841 cagcaggtac acctaagcaa gtggctcgca acagcaagtc tatcacaggt cagtacttgt
    27901 caggcaaacg tgtcatccca gtaccagaag agcgccgtgt cggaaatggt cgttttattg
    27961 aagtgatagg agcgcgtgag aacaacttgc aaaatgtcac ggctcgcttt ccactaggaa
    28021 aatttatcgc agtgacaggt gtgtcgggtt cagggaaatc gactctaatc aacagcattc
    28081 tcaaaaaagc cattgcccag aagctcaacc gtaattcaga caaacctggt aagtttaaga
    28141 ctattacagg gattgagcat gtcgaccgtt tgattgatat tgaccagagc cctatcggac
    28201 ggacgccgag gtctaaccca gctacctata caggagtttt tgacgatata cgtgaccttt
    28261 ttgctcagac aaatgaagcc aagattcgag gctacaagaa ggggcgcttc agtttcaacg
    28321 tcaagggagg tcgctgtgaa gcttgctcag gtgacgggat tatcaagatt gagatgcact
    28381 tcttgccaga tgtttatgtg gcttgtgaag tttgccacgg aacccgctat aacagtgaaa
    28441 ccctagaagt tcactacaag gaaaagaata tttcgcaggt cttggatatg acggtcaacg
    28501 atgcggtaga atttttccaa cacattccga aaattcaacg caaactccag accatcaagg
    28561 atgtagggct aggctatgtg accttgggac agccagctac caccctttct gggggagaag
    28621 cccaacgtat gaagttagct agcgaactcc acaaacgctc gacaggaaaa tctttctaca
    28681 ttctggatga gccgacgaca gggcttcata cagaggacat tgctcgcctg ctcaaggttt
    28741 tagctcgctt tgtagacgat ggcaatacag tcctcgtcat cgagcacaat ctggatgtta
    28801 tcaagacggc agaccatatc attgacttgg gacctgaggg cggtgtcggt ggtggaacca
    28861 tcatcgtaac aggaactcca gaagaagtag ctgccaacga agccagctat acaggacact
    28921 atttgaaagg aaagttacat catgaataaa cgcgtacaag catttctagc taaaatgcaa
    28981 gaaaaagaac tagatggtgt catcatcaac aatcttaaaa acgtctatta tttgactggt
    29041 ttttggggct caaacggaac agtctttatc agccgtgacc gtcaggtctt agtgacagac
    29101 tctcgctata tcatcgcagc taagcaagaa accagtggtt ttgagattgt ggctgatcgt
    29161 gatgaattgg ctgtcattgc aggaattgtt aaggacatgg gcttgactcg tatcggtttt
    29221 gaagatgaga tttcagtgtc ttattaccac cgtatgcagg cagcttttgc aggtttggac
    29281 ttgcttccac aaactcagtt tgtggaaggt cttcgtatga ttaaggatga ggcagagatt
    29341 gcagcgattc gcaaggcttg ttctatctca gaccaagctt tccgcgatgc gcttgacttt
    29401 atcaaaccag gaaaaactga aattgagatt gccaacttcc ttgatttccg catgcgtgag
    29461 ttgggagcat ctggcttatc ttttgatacg atcctagcta gcggtatcaa ttcttctaaa
    29521 ccccatgccc atccaatgca caaaccagtg gagttgggag aagccattac catggacttc
    29581 ggctgtctct atgaccacta tgtcagtgat atgacccgga ctatctatct agggcatgtt
    29641 agcgatgagc aggcagagat ttacaatacg gttctaaaag ctaaccaagc cttgattgac
    29701 caagctaagg caggcttagg tttccgtgac tttgacaaaa tccctcgtga tattatcatt
    29761 gaggcaggtt atggcgacta ctttactcac ggcattggcc acggtattgg tctggatatc
    29821 catgaggaac cctactttag ccagacttct acagaaacta ttaagacagg tatggccttg
    29881 accgatgaac caggtatcta tatcgaaggc aaatatggcg ttcgtatcga ggatgatatc
    29941 ctgattacag agacaggttg tgaattattg accctagctc caaaagagtt gatagtcatt
    30001 tagttgtttg tcaagaaaaa agtacgaaaa tgacgaaaaa agtcaaaaaa aattaaaaat
    30061 aggtcgcaag tcggatgttt tttatggtat aatagactaa actgatagta acatgtagcg
    30121 aaaggggtag gtacatgatt aaaatttata cagtctcaag ttgtactagc tgtaaaaaag
    30181 caaaaacctg gctcaatgcc caccagttaa gttataaaga acaaaacctt ggtaaagaag
    30241 gaattacgag agaagaatta ctggatattc taaccaaaac agataacgga atagccagca
    30301 tcgtttcgtc taaaaatcgc tatgccaaag cccttggagt ggatattgaa gatttgagtg
    30361 tcaatgaagt tctcaatctg attatggaaa caccgagaat tttaaagagc ccaatccttg
    30421 tagatgaaaa acgcctgcaa gttggctaca aggaagacga tattcgtgcc ttcctaccac
    30481 gctctgtccg taatgtagaa aatgcagaag cacgtttacg tgcagctcta taaacatcaa
    30541 ggctgggagc acttcccagt cttattctat tttaatttca aaaagaaaga agagagaaat
    30601 gaaaaaaata gttcttgtta gtctagcttt cctttttgtc ctggttggtt gcggacagaa
    30661 aaaagaaact ggaacagcta caaaaacaga aaaggatacg cttcagtcgg cattgccagt
    30721 tattgaaaat gccgagaaga atacagttgt aaccaagact ttggtcttgc ccaagtcaga
    30781 tgatggtagc cagcagacac aaacaattac ttacaaagac aagacttttt tgagtctaac
    30841 tatccaacaa aaacgtccag tctctgatga gttgaagact tatattgacc aacatggagt
    30901 ggaggaaact caaaaagctc ttcttgaagc ggaggagaag gataagtcta tcattgaagc
    30961 tcgtaaattg gcaggtttca aacttgaaac aaaactattg agcgcaacgg aacttcaaac
    31021 aacgactagt tttgattttc aagttctgga tgtcaagaag gcttcccagt tggaacatct
    31081 gaagaatatt ggtttggaaa atcttttgaa aaatgaacca agcaaatata tttcagatag
    31141 attggcaaat ggcgcgacag aacaatagaa aatccaaata aatagactgc ctgaattgta
    31201 gaaggtaagg aattatgcta taatggtact attctaagga aagagggtgt tagaatggga
    31261 tttactgaag aaacagtacg ttttaaattg gacgattcca ataaaaaaga aattagcgaa
    31321 actttgacag atgtttatgc ttcgttgaac gataagggtt acaacccaat taaccaaatc
    31381 gtaggttacg tattgagtgg agaccctgcc tacgttcctc gttataataa tgcacgaaat
    31441 caaatccgta agtatgagcg tgatgaaatc gttgaggaat tggttcgcta ctacctcaaa
    31501 ggacaaggag tcgatctata acctatgaga attatgggat tggacgtcgg ttcaaaaacg
    31561 gtaggggtgg cgattagcga tccgcttggt tttacagctc aagggcttga aatcatccag
    31621 ataaatgaag aacaaggcca atttggtttt gaccgcgtta aggaattggt tgatacttac
    31681 aaggtggaac gatttgtagt gggcttgcct aaaaacatga acaatacaag tggaccgcgc
    31741 gtagaagcta gtcaagccta cggagcaaag ctagaagagt tttttggttt accagtagac
    31801 tatcaggatg aacgcttgac aacagtggct gctgagcgca tgttgattga acaagcagat
    31861 atcagtcgca ataagcgcaa gaaagtcatt gataagttag cagctcagct gattttacaa
    31921 aattatttag atagaaaatt ttaatataaa ggagaggcta tgtcacacga tcataaccac
    31981 gaccacgaag aacgtgaact aatcacacta gtagatgagc aaggaaatga aaccttgttt
    32041 gaaatccttt tgacaattga tggaaaagaa gaatttggta aaaactatgt tcttctagta
    32101 ccagttaacg cagaagaaga cgaagacgga caagttgaaa tccaagctta ctcattcatt
    32161 gaaaatgaag atggaacaga aggcgaattg caaccaatcc cagaagactc agaagacgaa
    32221 tggaacatga ttgaagaagt cttcaacagc tttatggagg agtgatacag tctgggagac
    32281 tgtatcagcc caactcccag aaattgggaa gagttggaat gtcctgtgga tgtttttagc
    32341 ccacgttaac atttatagta gctagttatt agctaaccag gtaagaggtc gggacgaaaa
    32401 tcctggcctt gtttttatta gtaaccatac tttaatgcga taattgattg gacttttgtc
    32461 aaggagatgt gtatgtttga agtagaagag tggcttcata gtcggattgg tttgaatttt
    32521 aggtcaggtt taggccgaat gcagcaagca gtggatttgt taggaaatcc cgagaagtct
    32581 taccctatta tccacgtaac agggactaat gggaaaggat ctaccattgc ttttatgagg
    32641 gagttattta tgggacatgg caaaaaagtc gcgaccttta cctctcctca tatcgtatcc
    32701 atcaatgacc gaatctgcat taatgggcaa cctatagcag acacagactt catccgtttg
    32761 gccgagcagg tcaaggagat ggagaaaacg cttctgcaaa cccatgatca gttgtccttt
    32821 tttgaattgc tgaccttgat tgcttttctt tattttaggg agcaagaggt ggatttggtt
    32881 ttactagaag tgggaattgg tggcttactt gacacgacca atgtggtaac tggagagctt
    32941 gctgtcatca cctccatcgg gctcgaccat caggagacct tgggtgatag tctggaagca
    33001 atcgcagagc agaaagctgg tattttcaag gctggtaaga aggcagtgat tgcgaaattg
    33061 gctccagaag ctaggcttgt ctgtcagaaa aaagccgaat ctttagctgt tgacctttat
    33121 caggcaggtc aagatttttc aatgctgaat ggggattttt caagctcttt ggttaacctg
    33181 tcacagttga aaataggttt agaaggagct tatcagcagg aaaatgcagc cttggcgttg
    33241 caaacgtttc ttctttttat gggagaaaga aaggaaactg ttgatgaaca ggctgtaaga
    33301 caggctttgg agaagaccca ttgggctggg cgtttggagc gtattcgtcc gcagatttat
    33361 ttggatggtg ctcataacct ccctgccttg actcgcttgg ttgaatttat caaagaaaaa
    33421 gagcaggaag gttatcgtcc tcaaatcctt tttggagcct tgaaacggaa ggattatcaa
    33481 gggatgttgg cttatctgac tcaaaaattg cctcaggtgg aactcaaggt gaccggcttt
    33541 gactatcaag gttctctgga cgagacagat gtaataggtt acgatatagt tccttcttac
    33601 cgagaattta ttagcagttt tgaagaaaga gcagatgctc aggatttgtt gttcgttaca
    33661 ggatctctct attttatctc agaagtacgg ggctatctac tggggcatga gcagataaat
    33721 tgacctcttc ttttgtcttt gttatactag atgaattgct ggctaaggaa aatctatttt
    33781 tctagcatgg caagagaaag gacatttatt atgacattca aaacagcagc actttctatt
    33841 gtttctttag cgagtgtatc tttgctagtt gcttgttccc aaagaacaca accagttcaa
    33901 cagcctgtgg ctcagcagca ggtccaacaa cctgctcaac aacctgctca acagaatacc
    33961 aatactgcaa atgcaggaag taatcaaaat caagcggctc cagtacagaa ccaacctgtt
    34021 gctcaaccga ctgatattga tgggacttat acaggccaag atgacggaga ccgtatcact
    34081 ttagtggtca ctggaacgac tggtacatgg actgagctcg aatctgacgg ggatcagaaa
    34141 gtcaaacagg tcacatttga tgcagcaaat caacgcatga ttattggcga tgatgtcaaa
    34201 atttacactg taaacggtaa tcaaatcgtc gtagatgata tggatagaga cccatcggac
    34261 caaatcgttt taactaaata agactatgca agtagaaagg gctggatttt tcagcctttt
    34321 tacttttgct tagaaaataa tcataaatac ttgccttctg tcgaatacct gagttatact
    34381 agtatcaatt acttgttttt agcattcata ctcttcgaaa atcaaattca aaccgcgtca
    34441 acgtcgcctt gccgtactca agtacagcct gcggctagtt tcctagtttg ctctttgatt
    34501 ttcattgagt atcaaaatat caaggagggg atatgaaata tagaaaattt caattattga
    34561 tgtccaagta tggctttagt ctttcgatta tgctacttga actttgtctg gtttttggtc
    34621 tctttcttta tttaggacgc atggctccca ttttatggat tactgtcctc attctattga
    34681 gtatcatcac aatcatttcg atagtcaacc gtaatacgac tcctgagaat aaggtaacct
    34741 ggttattagt agcctttgtg ccagtatttg gccccttgct ctatctgatg tttggtgaaa
    34801 ggcgattgtc caaaaaagaa atcaaacaac tgaagaagct aggctccatg catttccaag
    34861 aagcaaatag ccagctacta aaagaggaat taaaagaaag tgataaggca gcttatggcg
    34921 tcatcaagtc cttattgagt atggatacca atgctgacat ctatgatcaa actgcctcta
    34981 cattttttcc taacggagag gctatgtgga aaaagatggt agaagatctt aaaaaggctg
    35041 agaaatttat tttcttggaa tattacatta tagaagaagg tttgatgtgg aatcgcatac
    35101 tagatatact agagcaaaag gtagctcagg gtgtagaggt taagatgctc tatgatgata
    35161 tcggctgtat ggctacttta acaggagatt atgcacatcg acttcgtcag ctgggcatcg
    35221 aggcccataa attcaataaa gttattcctc gtttgacagt ggcttataat aacagagatc
    35281 atagaaaaat attgattgtt gatggtcaga tagcctatac tggtggggtc aatctggcag
    35341 atgagtacat taaccacgtc gagagatttg gttattggaa ggatagtgga attcgcttag
    35401 acggactagc agtaaaagct ctgacacgct tatttttgac cacttggtac attaatcgag
    35461 gagaaattag tgattttgat caatatcatt tagaaaatca ttctatcccg agtgacggtt
    35521 taaccattcc atacggaagt ggacccaagc caatttttcg agcgcaggta gggaaaaaag
    35581 tttatcagag tttaatcaat caagcaacag aatcggtcta tattacgaca ccttatttga
    35641 ttatagatta tgatttaaca gagacaatca aaaatgcagc tatgagaggg gtcgatgttc
    35701 gaattatcac cccttacata ccagataaga agttcattca gttagtcacg agaggagctt
    35761 atcccgacct tctttctgct ggtgttcgga tttatgagta tagtccaggt tttattcata
    35821 gtaagcagat gttggtagac gaagattttg cggtggtggg gacaatcaat ctcgactacc
    35881 ggagcttggt acaccattat gaaaatgcag tcttactcta taaaactcct tctataaggg
    35941 aaatcgcccg agattttcga aatatatttg cagattctca ggaagtctat cctcattcta
    36001 tcaaaacgag ctggtatcaa aagcttgtaa aagaaatcgc ccagctattc gcccctatct
    36061 tataagaaat ctagaactta ggatacaaac cagacctatt tttcttgtct tttacgaata
    36121 gaaagaaaga ggaggggaat tcatgctaac taaggaagaa gtgaatgata tgattgagtt
    36181 caaacagaca catttacacc gctttcggga aattgaaacc tttgtgaaac tatgcaaaaa
    36241 atcactcaaa cagccatcgc aagctgacaa tcctaggact ttttgatata ctaagacaga
    36301 taaattgaac aggagaaacg atatgagtgt gtatggtaga gtagaagaag ttcataagga
    36361 gaatcgtgaa cctctagaat accaaatcga acaagaatcg catcatcgtg aatcaagtcg
    36421 tcttcctttg gtgaaaattt tactatggag tacgcttgta acggggataa ctctaggagt
    36481 gccgctatta ctcgacttaa tgagtgcaca agaagtgcag gatttttatg caggttgggc
    36541 gcttcatcag acagggaaga tttacagcga ctattatgga agtcaaggtt tgctttatta
    36601 tttgctgact tacgtgagtc agggcggatt tttctttgcc atctttgagt ggttagcctt
    36661 ggtagcagga ggatttttcc tttttagatc agcggacacc ttgacagagc aaggagacca
    36721 agctggacat ctggtgacta ttttttacat gctagttaca ggtcttgctt ttggtggagg
    36781 ctatgcgact cttttagcgc ttcctttctt attcgcagcc tttagtttag ttgcggctta
    36841 cctaagcaat ccaagccatg ataagggatt tgtacggatt gggctagctt tggcaggcgg
    36901 atttttcttt gctcccttat catcgctcct gtttattgct gtagtgagtt taggcttgtt
    36961 ggtctttaac cttgggcata gacgttttgt gcatgggttt tatcagtttc ttgcagtggc
    37021 tttaggtttt tcacttgtct tttatccaac tgcctactat agtgctgcaa caggaagttt
    37081 tggggatgcg attagtggta ttcgttatcc tattgacagt attcgctttg attttacttc
    37141 taaaatttta gagaatatgt ttttttatgg cttgttgtcc cttggtttgg gatttgtggt
    37201 ttgtatcttt ttaggtctct ttcaatccaa accctttaaa ctatacgtca tttcggttcc
    37261 tgcaagtctt gtggtaattt taggtttgat tttacttttc ttttcacaag agcctctgca
    37321 cgcttcttat ttgatggtcg tcttccctgt tttcctactt ttattggtaa ccaatattaa
    37381 gagtcaacag agggggcgta gtgctagaag aagccgaaga gaaacgccag ttagcctatg
    37441 gagtcgtttc ttcaaaggaa atctatatct gctagttttt gggtttgtct atcttttgtc
    37501 tgttcctttt ttgatgaagt ttgtccttta tccagtacct tatcaagaac gtaatcgtct
    37561 tgctgatttg gtaaaagagg agacaaatac ggaagatgct atctatgcat gggatgatac
    37621 tgcgactctt tatcgtaaga gtgagcgctt gtcgccatcg gcgattttgt ccccgttgca
    37681 ctatacagca actgaggaaa atcgtaataa gttacttaat gacttgaaag aaaaacaacc
    37741 taaggtgatt gtggtaaatg acaaggtggt agtctggtct gaagtggaaa cactcttaaa
    37801 agaaaattac caacaagtaa agactgatta ctcagagttt aaagtctata aaattaaata
    37861 accaaatcaa tatcttgtgt atttttaaaa attttaggat ttttaacaca agatattgat
    37921 ttttcttttt agagtggtat aatacttttt agaaagaaca ttttagaaaa gagcatgcgt
    37981 atgattgcac tagaagaaaa aattacaatt ttgccaactc tcttcgtcga gaaacgagat
    38041 gggagacgtg ttgtatttga tgtggacaag attgacaagg ctctccacaa ggcggctgac
    38101 aaggttatgg atgtgacacc cctggttgaa aaacgcctca atgatctgac tgagcgaatt
    38161 attacagaaa ttcatagtcg ctttccacag ggaattaaga tttacgaaat tcaaaatatc
    38221 gtagaacatg aactccttga agccaaagaa tatgcgctgg ctgaggagta tattacttat
    38281 cggacacaga gggattttga gcgctcaaaa gcgacggata tcaactttag tattcataaa
    38341 cttctcaaca aagaccagac agttgtcaat gaaaatgcta ataaagacag tgatgtcttt
    38401 aacactcagc gtgatttgac agcagggatt gttgggaaat caatcggact gcaaatgctt
    38461 cctaagcacg tagccaatgc ccaccaaaag ggggatatcc actatcacga tttggactac
    38521 agtccctata cccctatgac caactgctgt ttggttgatt ttaagggtat gttggaaaat
    38581 ggttttaaga ttggaaatgc agaggtagag agtcccaagt ctatccagac tgcgacagca
    38641 cagatttctc aaatcattgc caacgttgct tctagccagt acggtggctg ttcagctgac
    38701 cgtatcgatg aaattttggc gccttatgca gagaagaact atcaaaaaca tctcaaagat
    38761 gcagaagagt gggtattgcc tgaaaaacgg gaagattacg cttggaagaa aacgcaaaag
    38821 gacatctacg atgccatgca atctcttgag tatgaaatca atactctctt cacttcaaat
    38881 ggacaaacac cttttacttc gttaggtttt ggtctgggaa ccagtcgttt tgaacgagaa
    38941 attcaaaaag ctattttaaa cattcgcatc aagggtcttg gttcagaaca ccgtacggct
    39001 atctttccta aacttatttt cactctgaaa agaggcctta atttagagga aggaactccc
    39061 aactacgaca tcaagcagtt ggctcttgag tgtgcaacca aacggatgta tccagatgtt
    39121 ttatcttacg ataagattgt tgacttgaca ggatccttca aggtgcctat gggttgccgt
    39181 tctttcctcc aaggatggaa ggatgaaaat ggtgtagaag tcaattcagg tcgcatgaat
    39241 ctgggtgttg tgacggttaa tctgcctcgt attgctcttg agtctgaagg tgatatgaat
    39301 aagttctggg aaatcttcaa cgagcgaatg aatatcgcag aagatgctct tgtttaccgt
    39361 gtcgaacgca ctaaagaggc gacaccagca aatgctccta ttctttatca gtacggtgct
    39421 tttggccatc gtctaggtaa agaagaaagt gttgaccagc tctttaagaa tcgtcgtgcg
    39481 accgtttcgc tgggctatat cggcttgtat gaagtagcga cagttttctt tggtaacagc
    39541 tgggaaagta atccagatgc taaggaattc acgctagaca tcattcacga tatgaaacgc
    39601 cgtgtagaag agtggtcaga ccaatatggc taccatttct ctatctactc aacaccatcc
    39661 gaaagtctga cagaccgttt ctgccgacta gatatagaca agtttggctc tattcctgat
    39721 atcacagaca aggaatacta caccaactct ttccactacg atgttcgtaa aaatccaaca
    39781 ccgtttgaaa aattggactt tgagaaagtc tatccagaag caggtgcgtc aggtggtttc
    39841 atccattatt gtgagtatcc agtccttcag caaaatccaa aggccttgga agctgtctgg
    39901 gattatgctt atgaccgtgt aggctatcta ggcaccaata ctccgattga ccgttgctac
    39961 aagtgtgact ttgaagggga ttttgaacca actgagagag ggtttgcttg tccaaactgt
    40021 ggcaatagcg atcctaaaac agtagacgtt gttaaacgga cttgtggcta tcttggcaat
    40081 cctcaagcaa gaccgatggt caacgggcgt cacaaggaaa tcgctgcgcg tgtcaaacat
    40141 atgaatggtt caacgattaa aatagctggg catcaagtaa caaattagaa agaaatgaaa
    40201 tggggaaata tcaactagac gataaggggc gcgcacaagt gacccgttat cacgagaaat
    40261 actctaaagg tggagctggt aagaaagaac gcttgcttag cttcagagaa caatttttaa
    40321 acaagaacaa gaaaaaataa aagtgagagc cagctctcgc ttttctcata gtgggaggta
    40381 aggatggaat tacgcagacc aagattagcg gataagaaag ctgttttaga tatgatgaca
    40441 gagtttgaaa agagccaatc agcccatgat ggaggatttt gggatacaga gaactttgtg
    40501 tatgaagagt ggttggaaag caatcaggaa caggaaatgg ggattaatct gcctgaagga
    40561 tgggttcctg caattcagtt agtggctttt tctgagaaag gtcaagcagt tggatttctt
    40621 aatctccggt tgcgcctcag taactttcta ctagaagaag gtgggcacat tggctactcc
    40681 atccgtccat ctgaaagagg caagggttat gcaaaagaga ctctccgtca gggcttgcaa
    40741 gttgctaagg aaaagaacat caagaaagct ctggtgacct gtagcgtgaa taatcctgct
    40801 agcagagcag tcattctagc aaatggtgga atatttgagg atgctcacaa tggagtcgag
    40861 cgttattgga tagaggtagc gaatgaataa tccaaaacca caagaatgga aaagcgagga
    40921 acttagtcaa ggtcgtatca ttgactacaa ggcctttaac tttgtggacg gcgaaggcgt
    40981 gcgcaactct ctctatgtat caggctgtat gtttcactgc gagggatgtt ataatgttgc
    41041 gacttggtct tttaatgctg gcattcccta tacagcagaa ttagaagagc agatcatggc
    41101 agaccttgcc caaccctatg ttcaaggctt gactttgctg ggaggggaac cttttctcaa
    41161 tactggcatt ctcttgcctc tagttaaacg catccgaaag gaattgtcag acaaggacat
    41221 ttggtcctgg acgggctaca cttgggaaga aatgatgttg gaaactccag ataaactgga
    41281 actcttatca ttgattgaca ttcttgtcga tggacgatac gatcgaacta agagaaatct
    41341 catgctccag tttcgaggtt cgtccaacca acgaattatc gatgtgcaaa aatcgctcaa
    41401 aagtgggcaa gtagtgattt gggacaagct caatgacgga aaagaaagct atgaacaggt
    41461 gaagagagaa tgaagaaaaa agacttagta gaccaactag tctcagagat cgagacgggg
    41521 aaagtcagga cactgggaat atacggtcat ggagcttcag gtaaatcaac ctctgcacag
    41581 gaattgtacc aagctttaga ttctactaca gtaaatttgc tagaaacaga tccctatatc
    41641 acctcaggac gccatctggt agtacccaag gacgcgccga atcaaaaggt gacagccggt
    41701 ctgccagtgg cgcatgaact ggagagtttg cagagagata tccttgcctt gcaggcgagt
    41761 atggatgtct tgacaattga agaaccttgg aaggctagtg aggtcttgtc tggagccaaa
    41821 ccaattttga ttgtcgaagg gatgtctgtt ggctttcgac ccaaggaact ctttgaaaaa
    41881 accatctgtt tctacacgga tgaggagacc gaattaaagc gacgccttgc tagagatacg
    41941 actgtgagaa atcgtgatgc atcctttata ttggctagcc atcagatgag acgggagcag
    42001 tatctgcgat actataaaga aactgagtct aaggcggata tcttagtgga tcaatcagaa
    42061 gataaatttg atgtcaagag gacttaactt atgtatagaa gaaatataga agaaaatccc
    42121 taattttaga aagaaaaagt aggaaaacag tttcatccca aaaaaacgaa aaaacctaac
    42181 aaatcccttg caatcgcagg ggatttgtgt tattctatta tggtgctgta aattacagcc
    42241 ttagttttga tgcaagaggt tgcgacacgc tcggttgcat tgccacgcaa caccgtgtcg
    42301 gttttcttgt ggagctagcc tattatctta aatagacgaa aaggagaaaa agatggcaaa
    42361 caaaaaaatc cgtatccgtt tgaaagctta cgaacaccgt acgcttgaca cagcggctgc
    42421 aaaaatcgta gaatcagcta ctcgtacagg tgcacaagtt gcgggtccaa tcccacttcc
    42481 aactgaacgt agcctctaca caatcattcg tgcgactcac aaatacaaag actctcgcga
    42541 acaatttgaa atgcgtacac acaaacgttt gatcgatatc gttaacccaa ctcaaaaaac
    42601 agttgatgcc ttgatgaaat tggatcttcc aagtggtgta aacgtagaaa tcaaacttta
    42661 atctaaaata taaaagagca gaggctggtg tttcaatcta attgaacacg ggctaaactc
    42721 ggtgtgaaaa agataaactt cctagtgtct gctagacact gcgtcagttt cctattttca
    42781 agttgagttt gacgcccttt gtatcttaga cttgagcata aaaaacgctc gttaaaaact
    42841 ttttgaataa aaaatataga aaaggaacta ttttctcatg acaaaaggaa tcttagggaa
    42901 aaaagtggga atgactcaaa tcttcactga agctggcgaa ttgatccctg taacagttat
    42961 tgaagcaact ccaaacgttg ttcttcaagt taaaactgtt gaaacagacg gatacaacgc
    43021 tatccaagtt ggtttcgatg acaaacgcga agtattgagc aacaaacctg ctaaaggaca
    43081 tgtagcgaaa gctaacacgg ctcctaagcg cttcattcgt gaattcaaaa acgttgaagg
    43141 cttggaagtt ggtgctgaaa ttacagttga aacattcgca gctggagacg ttgttgacgt
    43201 aactggtact tctaaaggta aaggtttcca aggtgttatc aaacgccacg gacaatcacg
    43261 tggaccaatg gctcacggtt ctcgttacca ccgtcgtcca ggttctatgg gacctgttgc
    43321 acctaaccgc gtattcaaag gtaaaaacct tgcagggcgt atgggtggcg accgcgtaac
    43381 aattcaaaac cttgaagttg tacaagttgt tccagaaaag aacgttatcc ttatcaaagg
    43441 taacgtacca ggtgctaaga aatctcttat cactatcaaa tcagcagtta aagctggtaa
    43501 ataataaaga aaggggaaat cagtcacaat ggcaaacgta acattatttg accaaactgg
    43561 taaagaagct ggccaagttg ttcttagcga tgcagtattt ggtatcgaac caaatgaatc
    43621 agttgtgttt gatgtaatca tcagccaacg cgcaagcctt cgtcaaggaa cacacgctgt
    43681 taaaaaccgc tctgcagtat caggtggtgg acgcaaacca tggcgtcaaa aaggaactgg
    43741 acgtgctcgt caaggttcta tccgctcacc acaatggcgt ggtggtggtg ttgtcttcgg
    43801 accaactcca cgttcatacg gctacaaact tccacaaaaa gttcgtcgcc tagctcttaa
    43861 atcagtttac tctgaaaaag ttgctgaaaa caaattcgta gctgtagacg ctctttcatt
    43921 tacagctcca aaaactgctg aatttgcaaa agttcttgca gcattgagca tcgattctaa
    43981 agttcttgtt atccttgaag aaggaaatga attcgcagct ctttcagctc gtaaccttcc
    44041 aaacgtgaaa gttgcaactg ctacaactgc aagtgttctt gacatcgcaa atagcgacaa
    44101 acttcttgtc acacaagcag ctatctctaa aatcgaggag gttcttgcat aatgaatttg
    44161 tatgatgtta tcaaaaaacc tgtcatcact gaaagctcaa tggctcaact tgaagcagga
    44221 aaatatgtat ttgaagttga cactcgtgca cacaaacttt tgatcaagca agctgttgaa
    44281 gctgctttcg aaggtgttaa agttgccaat gttaacacaa tcaacgtaaa accaaaagct
    44341 aaacgtgttg gacgttacac tggttttact aacaaaacta aaaaagctat catcacactt
    44401 acagctgatt ctaaagcaat cgagttgttt gctgctgaag ctgaataatc taaggaggaa
    44461 atatcgtggg aattcgtgtt tataaaccaa caacaaacgg tcgccgtaat atgacttctt
    44521 tggatttcgc tgaaatcaca acaagcactc ctgaaaaatc attgcttgtt gcattgaaga
    44581 gcaaggctgg tcgtaacaac aacggtcgta tcacagttcg tcaccaaggt ggtggacaca
    44641 aacgtttcta ccgtttggtt gacttcaaac gtaataaaga caacgttgaa gcagttgtta
    44701 aaacaatcga gtacgatcca aaccgttctg caaacatcgc tcttgtacac tacactgacg
    44761 gtgtgaaagc atacatcatc gctccaaaag gtcttgaagt aggtcaacgt atcgtttcag
    44821 gtccagaagc agatatcaaa gtcggaaacg ctcttccact tgctaacatc ccagttggta
    44881 ctttgattca caacatcgag ttgaaaccag gtcgtggtgg tgaattggta cgtgctgctg
    44941 gtgcatctgc tcaagtattg ggttctgaag gtaaatacgt tcttgttcgt cttcaatcag
    45001 gtgaagttcg tatgattctt ggaacttgcc gtgctacagt tggtgttgtc ggaaacgaac
    45061 aacatggact tgtaaacctt ggtaaagcag gacgtagccg ttggaaaggt atccgcccaa
    45121 cagttcgtgg ttctgtaatg aaccctaacg atcacccaca cggtggtggt gaaggtaaag
    45181 caccagttgg tcgtaaagca ccatctactc catggggcaa acctgctctt ggtcttaaaa
    45241 ctcgtaacaa gaaagcgaaa tctgacaaac ttatcgttcg tcgtcgcaac gagaaataat
    45301 attaaactag tcgcttaagc aactagtaaa tccgccagct cggtagcgct ccataggagt
    45361 gcaagccgct gtggtacaac atttaaagga gaaaatataa aaatgggacg cagtcttaaa
    45421 aaaggacctt tcgtcgatga gcatttgatg aaaaaagttg aagctcaagc taacgacgaa
    45481 aagaaaaaag ttattaaaac ttggtcacgt cgttcaacga tcttcccaag tttcattggt
    45541 tacactattg cagtttatga cggacgtaaa cacgtacctg tttacatcca agaagacatg
    45601 gtaggccaca aacttggtga atttgcacca actcgtactt acaaaggtca cgctgcagac
    45661 gacaagaaaa cacgtagaaa ataaggagaa cataaatggc agaaattact tcagctaaag
    45721 caatggctcg tacagtacgt gtttcacctc gtaaatcacg tcttgttctt gataacatcc
    45781 gtggtaaaag cgtagccgat gcaatcgcaa tcttgacatt cactccaaac aaagctgctg
    45841 aaatcatctt gaaagttttg aactcagctg tagctaacgc tgaaaacaac tttggtttgg
    45901 ataaagctaa cttggtagta tctgaagcat tcgcaaacga aggaccaact atgaaacgtt
    45961 tccgtccacg tgcgaaaggt tcagcttcac caatcaacaa acgtacagct cacatcactg
    46021 tagctgttgc agaaaaataa ggaggtaaaa tcgtgggtca aaaagtacat ccaattggta
    46081 tgcgtgtcgg catcatccgt gattgggatg ccaaatggta tgctgaaaaa gaatacgcgg
    46141 attaccttca tgaagatctt gcaatccgta aattcgttca aaaagaactt gctgacgcag
    46201 cagtttcaac tattgaaatc gaacgcgcag taaacaaagt taacgtttca cttcacactg
    46261 ctaaaccagg tatggttatc ggtaaaggtg gtgctaacgt tgatgcactc cgtgcaaaac
    46321 ttaacaaatt gactggaaaa caagtacaca tcaacatcat cgaaatcaaa caacctgatt
    46381 tggatgctca ccttgtaggt gaaggaattg ctcgtcaatt ggagcaacgt gttgctttcc
    46441 gtcgtgcaca aaaacaagca atccaacgtg caatgcgtgc tggagctaaa ggaatcaaaa
    46501 ctcaagtatc aggtcgtttg aacggtgcag atatcgcccg tgctgaagga tactctgaag
    46561 gaactgttcc gcttcacaca cttcgtgcag atatcgatta cgcttgggaa gaagcagata
    46621 ctacatacgg taaacttggt gttaaagtat ggatctaccg tggtgaagtt cttccagctc
    46681 gtaaaaacac taaaggaggt aaataaccaa tgttagtacc taaacgtgtt aaacaccgtc
    46741 gtgagttccg tggaaaaatg cgcggtgaag caaaaggtgg aaaagaagta gcattcggtg
    46801 aatacggtct tcaagctaca actagccact ggatcactaa ccgccaaatc gaagctgctc
    46861 gtatcgccat gactcgttac atgaaacgtg gtggtaaagt ttggattaaa atcttcccac
    46921 acaaatcata cactgctaaa gctatcggtg tgcgtatggg atctggtaaa ggggcacctg
    46981 aaggttgggt agcaccagtt aaacgtggta aagtgatgtt cgaaatcgct ggtgtatctg
    47041 aagagattgc acgtgaagcg cttcgacttg ctagccacaa attgccagtt aaatgtaaat
    47101 tcgtaaaacg tgaagcagaa taaggagaag gcatgaaact taatgaagta aaagaatttg
    47161 ttaaagaact tcgtggtctt tctcaagaag aactcgcgaa gcgcgaaaac gaattgaaaa
    47221 aagaattgtt tgaacttcgt ttccaagctg ctactggtca attggaacaa acagctcgct
    47281 tgaaagaagt taaaaaacaa atcgctcgta tcaaaacagt tcaatctgaa gcgaaataat
    47341 agactaggga aggagaaatt tcaatggaac gcaataatcg taaagttctt gttggacgtg
    47401 ttgtatctga caaaatggac aagacaatca cagttgtagt tgaaacaaaa cgtaaccacc
    47461 cagtctatgg taaacgtatt aactactcta aaaaatacaa agctcatgat gaaaacaatg
    47521 ttgccaaaga aggcgatatc gtacgtatca tggaaactcg cccgctttca gctacaaaac
    47581 gtttccgtct tgtagaagtt gttgaagaag cggtcatcat ctaatcaaac ctgaaaggag
    47641 aaaactgaaa tgattcaaac agaaactcgt ttgaaagtcg cagacaacag cggtgctcgc
    47701 gaaatcttga ctatcaaagt tcttggtggt tcaggacgta aatttgcaaa catcggtgat
    47761 gttatcgtgg catctgtaaa acaagctact cctggtggtg cggttaaaaa aggtgacgtt
    47821 gttaaagcag ttatcgttcg tactaaatca ggtgctcgtc gtgctgatgg ttcatacatc
    47881 aaatttgacg aaaacgcagc agttatcatc cgtgaagaca aaactcctcg cggaacacgt
    47941 atctttggcc cagttgcacg tgaattgcgt gaaggtggct tcatgaagat cgtgtcactt
    48001 gctccagaag tactttaatt tttaggaaca aactagtccc ctagcttcaa gctagggtgc
    48061 ccttatgggc gtaagaaaaa tcaaggagaa acctaatgtt tgtaaaaaaa ggcgacaaag
    48121 ttcgcgtaat cgctggtaaa gataagggaa cagaagctgt tgtccttact gcccttccaa
    48181 aagtaaacaa agttatcgtt gaaggtgtta acattgttaa gaaacaccaa cgtccaacta
    48241 acgagcttcc tcaaggtggt atcatcgaga aagaagcagc tatccacgta tcaaacgttc
    48301 aagttttgga caaaaatggt gtagctggtc gtgttggtta caaatttgta gacggtaaaa
    48361 aagttcgcta caacaaaaaa tcaggcgaag tgcttgatta atcacgaagg aaaggagaag
    48421 tataatggca aatcgtttaa aagaaaaata tcttaatgaa gtagttcctg ctttgacaga
    48481 acaattcaac tactcatcag tgatggctgt gcctaaagta gataagattg ttttgaacat
    48541 gggtgttggt gaagctgtat caaacgctaa aagccttgaa aaagctgctg aagaattggc
    48601 acttatctca ggtcaaaaac cacttatcac taaagctaaa aaatcaatcg ccggcttccg
    48661 tcttcgtgaa ggtgttgcga tcggtgcaaa agttaccctt cgtggtgaac gtatgtacga
    48721 attcttggat aaattggtat cagtttcact tccacgtgta cgtgacttcc acggtgtccc
    48781 aacaaaatca tttgatggac gcgggaacta cacacttggt gtgaaagaac aattaatctt
    48841 cccagaaatc aacttcgatg acgttgacaa aactcgtggt cttgacatcg ttatcgtaac
    48901 aactgctaac actgacgaag agtcacgtgc attgcttaca ggccttggaa tgccttttgc
    48961 aaaataatat aggaggtaaa tctaatggct aaaaaatcaa tggtagctag agaggctaaa
    49021 cgccaaaaaa ttgttgaccg ttatgctgaa aaacgtgctg cattaaaggc ggcaggggac
    49081 tacgaaggtt tatctaaatt acctcgcaac gcttcaccga ctcgtttaca taatcgttgt
    49141 agagttacgg ggcgcccaca ttcagtttac cgcaaatttg gtctgagtcg tatcgctttt
    49201 cgcgaacttg cgcataaagg tcaaattcct ggtgtaacaa aagcatcttg gtaatttaag
    49261 atatcaaggg cgtcaaaact ccaagtaaaa ataggaaact tgacgaagaa actaaagttt
    49321 ctaggaaagt ttatcttttt cacacagagt ttagcccggg ttcaattggg cttgccaatt
    49381 tgaacacgag ctacagcttt ggcaaaaaag accaatttgc tttggagcat tgcttctgca
    49441 ttaaattgtc tatttttgct cgtgctgtta cgctctttgt atcatgtatt aactagcaag
    49501 tgcaacttgc aaactactag taagaggaga aaaacaaaat ggttatgact gacccaatcg
    49561 cagacttcct aactcgtatt cgtaatgcta accaagctaa acacgaagta cttgaagtac
    49621 ctgcatcaaa catcaaaaaa gggattgctg aaatccttaa acgcgaaggt tttgtaaaaa
    49681 acgttgaaat catcgaagat gacaaacaag gcgtcatccg tgtatttctt aaatacggac
    49741 caaatggtga aaaagttatc actaacttga aacgtgtttc taaaccagga cttcgtgtct
    49801 acaaaaaacg tgaagacctt ccaaaagttc ttaacggact tggaattgcc atcctttcaa
    49861 cttctgaagg tttgcttact gataaagaag cacgccaaaa gaatgttggt ggtgaggtta
    49921 tcgcttacgt ttggtaaaat caagatacaa agctcgtaaa gaacaaagca aaattaggaa
    49981 gttggagaag tttgtttaca aacaagccaa cttatctatt ttgcacagtt cttagagcgt
    50041 gttcagttca gctcttgaac taaataagta tctgaacccc gtgaaaactg gccgttttgg
    50101 cctgacaatt taacaggaga aaataaacat gtcacgtatt ggtaataaag ttatcgtgtt
    50161 gcctgctggt gttgaactcg ctaacaatga caacgttgta actgtaaaag gacctaaagg
    50221 agaacttact cgtgagttct caaaagatat tgaaatccgt gtggaaggta ctgaagtaac
    50281 tcttcaccgt ccaaacgatt caaaagaaat gaaaactatc cacggaacta ctcgtgccct
    50341 tttgaacaac atggttgttg gtgtatcaga aggattcaag aaagaacttg aaatgcgtgg
    50401 ggttggttac cgtgcacagc ttcaaggatc aaaacttgtt ttggctgttg gtaaatctca
    50461 tccagacgaa gttgaagctc cagaaggaat tacttttgaa cttccaaacc caacaacaat
    50521 cgttgttagc ggaatttcaa aagaagtagt tggtcaaaca gctgcttacg tacgtagcct
    50581 tcgttcacca gaaccatata aaggtaaagg tatccgttac gttggtgaat tcgttcgccg
    50641 taaagaaggt aaaacaggta aataatgttg agtggttgat catcaaccac caacctattt
    50701 tccaactttg tgcatagcac acgatttaaa actaaagagg tgaaaactgt gatttcaaaa
    50761 ccagataaaa acaaactccg ccaaaaacgc caccgtcgcg ttcgcggaaa actctctgga
    50821 actgctgatc gcccacgttt gaacgtattc cgttctaata caggcatcta cgctcaagtg
    50881 attgatgacg tagcgggtgt aacgctcgca agtgcttcaa ctcttgataa agaagtttca
    50941 aaaggaacta aaactgaaca agccgttgct gtcggtaaac tcgttgcaga acgtgcaaac
    51001 gctaaaggta tttcagaagt ggtgttcgac cgcggtggat atctatatca cggacgtgtg
    51061 aaagctttgg ctgatgcagc tcgtgaaaac ggattgaaat tctaatagga ggacactaga
    51121 aaatggcatt taaagacaat gcagttgaat tagaagaacg cgtagttgct gtcaaccgtg
    51181 ttacaaaagt tgttaaaggt ggacgtcgtc ttcgtttcgc agctcttgtt gttgttggtg
    51241 accacaatgg tcgcgtagga tttggtactg gtaaagctca agaagttcca gaagcaatcc
    51301 gtaaagcagt agatgatgct aagaaaaact tgatcgaagt tcctatggtt ggaacaacaa
    51361 tcccacacga agttctttca gaattcggtg gagctaaagt attgttgaaa cctgctgtag
    51421 aaggttctgg agttgccgct ggtggtgcag ttcgtgccgt tgtggaattg gcaggtgtgg
    51481 cagatattac atctaaatca cttggttcta acactccaat caacattgtt cgtgcaactg
    51541 ttgaaggttt gaaacaattg aaacgcgctg aagaaattgc tgcccttcgt ggtatttcag
    51601 tttctgattt ggcataagaa aggggataaa atggctcaaa ttaaaattac tttgactaag
    51661 tctccaatcg gatgcattcc atcacaacgt aaaactgttg tagcacttgg acttggcaaa
    51721 ttgaacagct ctgttattaa agaagataac gctgctatcc gtggtatgat cacagcagta
    51781 tctcacttag taacagttga agaagtaaac taatgaagtt ttaggggatg tgcactgtac
    51841 catcccctaa aactagatat agtcatctat gatgacatcg tataggcgag ttgatggggg
    51901 agacaacctt ttctccctta tcggcgctag cattttacaa aagaggagaa aataaaaatg
    51961 aaacttcatg aattgaaacc tgcagaaggt tctcgtaaag tacgtaaccg cgttggtcgt
    52021 ggtacttcat caggtaacgg taaaacatct ggtcgtggtc aaaaaggtca aaaagctcgt
    52081 agcggtggcg gagttcgcct tggttttgaa ggtggacaaa ctccattgtt ccgtcgtctt
    52141 ccaaaacgtg gattcactaa catcaacgct aaagaatacg caattgtgaa ccttgaccaa
    52201 ttgaacgtct ttgaagatgg tgctgaagta actccagttg ttcttatcga agcaggaatt
    52261 gttaaagctg aaaagtcagg tattaaaatt cttggtaacg gtgagttgac taagaaattg
    52321 actgtgaaag cagctaaatt ctctaaatca gctgaagaag ctatcactgc taaaggtggt
    52381 tcagtagaag tcatctaaga gaggtgacct atgtttttta aattattaag agaagctctt
    52441 aaagtcaagc aggttcgatc aaaaatttta tttacaattt ttatcgtttt ggtctttcgt
    52501 atcggaacta gcattacagt tcctggtgtg aatgccaata gcttgaatgc tttaagtgga
    52561 ttatccttct taaacatgtt gagcttggtg tcggggaatg ccctaaaaaa cttttcgatt
    52621 tttgccctag gagttagtcc ctatatcacc gcttctattg ttgtccaact cttgcaaatg
    52681 gatattttac ccaagtttgt agagtggggt aaacaagggg aagtaggtcg aagaaaattg
    52741 aatcaagcta ctcgttatat tgctctagtt ctcgcttttg tgcaatctat cgggattaca
    52801 gctggtttta ataccttggc tggagctcaa ttgattaaaa ctgctttaac tccacaagtt
    52861 tttctgacga ttggtatcat cttaacagct ggtagtatga ttgtcacttg gttgggtgag
    52921 caaattacag ataagggata cggaaacggt gtttccatga ttatctttgc cgggattgtt
    52981 tcctcaattc cagagatgat tcagggcatc tatgtggact actttgtgaa cgtcccaagt
    53041 agccgtatca cttcatctat cattttcgta atcattttga ttattactgt attgttgatt
    53101 atttacttta caacttatgt tcaacaagca gaatacaaaa ttccaatcca atatactaag
    53161 gttgcacaag gtgctccatc tagctcttac cttccgttaa aggtaaaccc tgctggagtt
    53221 atccctgtta tctttgccag ttcgattact gcagcgcctg cggctattct tcagtttttg
    53281 agtgccacag gtcatgattg ggcttgggta agggtagcac aagagatgct ggcaactact
    53341 tctccaactg gtattgccat gtatgctttg ttgattattc tctttacatt cttctatacg
    53401 tttgtacaga ttaatcctga aaaagcagca gagagcctac aaaagagtgg tgcctatatc
    53461 catggagttc gtcctggtaa aggtacagaa gaatatatgt ctaaacttct tcgtcgtctt
    53521 gcaactgttg gttccctctt ccttggtgtg atttccattt taccgattgc agctaaagat
    53581 gtatttggtc tttctgatgt tgttgccttt ggtggaacaa gtctcttgat cattatctct
    53641 acaggtatcg aaggaatcaa gcaattggaa ggttacctat tgaaacgtaa gtatgttggt
    53701 ttcatggaca gaacagaata aaagtattta ctgaatcagt aaatactgag ggagtggagg
    53761 tttaaactct gacatttgta agagttggat ctcccctctt ctattttgtt tttaaatagg
    53821 ggtgaaaaga ctttttgctt ctatttaaaa ataaaataag gagatcaaat catgaatctt
    53881 ttgattatgg gcttacctgg tgcaggtaag ggaactcaag cagcaaaaat cgtagaacaa
    53941 ttccatgttg cacatatctc aacaggtgat atgttccgcg ctgcaatggc aaatcaaact
    54001 gaaatgggtg ttcttgctaa gtcatatatt gacaagggtg aattggttcc tgacgaagtt
    54061 acaaatggaa tcgtaaaaga acgtctttca caagatgata ttaaagaaac aggattctta
    54121 ttggatggtt acccacgtac aattgaacaa gctcatgcct tggacaaaac attgaatgaa
    54181 cttggcattg aactagaagg tgttatcaat attgaagtga accctgacag ccttttggaa
    54241 cgtttgagtg gccgtatcat ccaccgcgta actggagaaa ctttccacaa ggtctttaac
    54301 ccaccagttg actataaaga agaagattac taccaacgtg aagatgataa gcctgagaca
    54361 gtaaaacgtc gtttggatgt taatattgct caaggagaac caatcattgc tcactaccgt
    54421 gccaaaggtt tggttcatga catcgaaggt aatcaagata tcaatgatgt cttctcagat
    54481 attgaaaaag tattgacaaa tttgaaataa agcgtttttc acacttgcaa aaatccgcta
    54541 caaatgttat actgaaatag tctgacttat aattgttgtc tctgtgtcta gaggcatcga
    54601 atcgaaattt atggaggtgc ttttgcgtgg caaaagacga tgtgattgaa gttgaaggca
    54661 aagtagttga tacaatgccg aatgcaatgt ttacggttga acttgaaaat ggacatcaga
    54721 ttttagcaac agtttctggt aaaattcgta aaaactatat tcgtatttta gcgggagatc
    54781 gtgttactgt cgaaatgagt ccatatgact tgacacgtgg acgtatcact taccgcttta
    54841 aataatcgaa aaacttggag ggataagaaa tgaaagtaag accatcggtc aaaccaattt
    54901 gcgaatactg taaagttatt cgtcgtaatg gtcgtgttat ggtaatttgc ccagcaaatc
    54961 caaaacacaa acaacgtcaa ggataagata gaaaggagaa aacatggctc gtattgctgg
    55021 agttgatatt ccaaatgaca aacgcgtagt aatctcattg acttatgttt atggtatcgg
    55081 acttgcaaca tctaagaaaa ttttggctgc tgctggaatc tcagaagatg ttcgtgtacg
    55141 tgatcttaca tcagatcaag aagatgctat ccgtcgtgaa gtggatgcaa tcaaagttga
    55201 aggtgacctt cgtcgtgaag taaacttgaa catcaaacgt ttgatggaaa tcggttcata
    55261 ccgtggtatc cgtcaccgtc gtggacttcc tgtccgtgga caaaacacta aaaacaacgc
    55321 tcgcactcgt aaaggtaaag ctgttgcgat tgctggtaag aaaaaataat ataggaggta
    55381 aaagtcttgg ctaaaccaac acgtaaacgt cgtgtgaaaa agaatatcga atctggtatt
    55441 gctcatattc acgctacatt taataacact attgttatga ttactgatgt gcatggtaat
    55501 gcaattgctt ggtcatcagc tggtgctctt ggtttcaaag gttctcgtaa atctacacca
    55561 ttcgctgctc aaatggcttc tgaagctgct gctaaatctg cacaagaaca cggtcttaaa
    55621 tcagttgaag ttactgtaaa aggtccaggt tctggtcgtg agtcagctat tcgtgcgctt
    55681 gctgccgctg gtcttgaagt aacagcaatt cgtgatgtga ctccagtgcc acacaatggt
    55741 gctcgtcctc caaaacgtcg ccgtgtataa tcatcgcatt acactgcttt tcgtttaaga
    55801 gggagtaact aaatgatcga gtttgaaaaa ccaaatataa caaaaattga tgaaaataaa
    55861 gattatggca agtttgtaat cgaaccactt gaacgtggct acggtacaac tcttggtaac
    55921 tctcttcgtc gtgtacttct agcttctcta ccaggagcag ctgtgacatc tatcaacatt
    55981 gatggtgtgt tacatgagtt tgacacagtt ccaggtgttc gtgaagacgt gatgcaaatc
    56041 attctgaaca ttaaaggaat tgcagtgaaa tcgtacgttg aagacgaaaa aatcatcgaa
    56101 ctggatgttg aaggtcctgc tgaagtaaca gctggtgaca ttttgacaga tagcgatatt
    56161 gaaattgtaa atccagatca ttatctcttt acaatcggtg aaggttcttc tctaaaagcg
    56221 actatgactg ttaacagtgg tcgtggatat gtacctgctg atgaaaataa aaaggataat
    56281 gcaccagttg gaacacttgc tgtagattct atttatacac cagttacaaa agtcaactat
    56341 caagtggaac ctgctcgtgt aggtagcaat gatggtttcg acaaattaac ccttgaaatc
    56401 ttgacaaatg gaacaattat tccagaagat gctttagggc tttcagcacg tattttgaca
    56461 gaacatcttg atttgtttac aaatcttact gagattgcta agtcaactga agtgatgaaa
    56521 gaagctgata ctgaatctga cgaccgtatt ttagatcgta cgattgagga actggacttg
    56581 tctgtgcgtt catacaactg tttaaaacgt gccggtatca atactgtgca tgatttgaca
    56641 gaaaaatctg aagcagagat gatgaaagta cgaaatcttg gacgcaagag tttggaagaa
    56701 gtgaaactca aactcattga tttgggtctt ggattaaaag ataaataaag gaggaataca
    56761 tggcttaccg taaactagga cgcactagct cacaacgtaa agcaatgctt cgcgatttga
    56821 caactgacct tttgatcaac gaatcaatcg tgacaactga agctcgtgct aaagaaatcc
    56881 gtaaaactgt tgaaaaaatg attactctag gtaaacgtgg tgatttgcat gcacgtcgtc
    56941 aagcagctgc tttcgtacgt aatgaaatcg catctgaaaa ctatgatgaa gcaactgata
    57001 agtacacttc tactacagca cttcaaaaat tgttctcaga aatcgcacct cgttatgctg
    57061 aacgtaacgg tggatacact cgtatcctta aaactgaacc acgtcgtggt gatgcagcgc
    57121 caatggcgat catcgaatta gtataaaatc atcaattttg ttgagtgtta tgatgatgga
    57181 gtcttgtgct cttagtctag ctctggtcta ccgctaggat ttcggtccta gcgggaacac
    57241 tcatcataag ttgggatagt agacgcttgt ttacgaaatt gtttttttct taagaacaac
    57301 ttcgtaagca ggcgtttttg agtattttcg ttagaattat gctatactat ttgaaaagaa
    57361 tcctgtttaa tgttaaggtt tcttatttta agaagaattg gagtttgctt atgaaagcga
    57421 ttataactgt tgttggtaaa gataaatctg gaattgttgc aggtgtttct ggtaaaattg
    57481 cagaattagg attgaatatt gacgatatct ctcaaactgt cttggatgaa tattttacga
    57541 tgatggctat tgtatctagt gatgaaaagc aagattttac ctatcttcgt aatgaatttg
    57601 aagcttttgg gcaaactttg aatgtaaaaa tcaatattca gagtgcagcg attttcgaag
    57661 ctatgtataa tatctaggag gttatcatgg atattagaca agttactgaa accatcgcca
    57721 tgattgagga gcaaaatttc gatatcagaa ccattaccat ggggatttct cttttggact
    57781 gtatcgatcc agatatcaat cgtgctgcgg agaaaatcta tcaaaaaatt acgacaaagg
    57841 cggctaattt agtagctgtt ggtgatgaaa ttgcggctga gttgggaatt cctatcgtta
    57901 ataagcgtgt atcggtgaca cctatttctc tgattggggc agcgacagat gcgacggact
    57961 acgtggttct ggcaaaagcg cttgataagg ctgcgaaaga gattggtgtg gactttattg
    58021 gtggtttttc tgccttagta caaaaaggtt atcaaaaggg agatgagatt ctcatcaatt
    58081 ccattcctcg cgctttggct gagacggata aggtctgctc gtcagtcaat atcggctcaa
    58141 ccaagtctgg tattaatatg acggctgtgg cagatatggg acgaattatc aaggaaacag
    58201 caaatctttc agatatggga gtggccaagt tggttgtatt cgctaatgct gttgaggaca
    58261 atccatttat ggcgggtgcc tttcatggtg ttggggaagc agatgttatc atcaatgtcg
    58321 gagtttctgg tcctggtgtt gtgaaacgtg ctttggaaaa agttcgtgga cagagctttg
    58381 atgtagtagc cgaaacagtt aagaaaactg cctttaaaat cactcgtatc ggtcaattgg
    58441 ttggtcaaat ggccagtgag agactgggtg tggagtttgg tattgtggac ttgagtttgg
    58501 caccaacccc tgcggttgga gactctgtgg cacgtgtcct tgaggaaatg gggctagaaa
    58561 cagttggcac gcatggaacg acggctgcct tggccctctt gaacgaccaa gttaaaaagg
    58621 gtggagtgat ggcctgtaac caggtcggtg gtttatctgg tgcctttatc cctgtttctg
    58681 aggatgaagg aatgattgct gcagtgcaaa atggctctct taatttagaa aaactagaag
    58741 ctatgacggc tatctgttct gttggattgg atatgattgc catcccagaa gatacgcctg
    58801 ctgaaactat tgcggctatg attgcggatg aagcagcaat cggtgttatc aacatgaaaa
    58861 caacagctgt tcgtatcatt cccaaaggaa aagaaggcga tatgattgag tttggtggtc
    58921 tattaggaac tgcacccgtt atgagggtta atggggcttc gtctgtcgac ttcatctctc
    58981 gcggtggaca aatcccagca ccaattcata gttttaaaaa ttaagaaaat aggagaaatt
    59041 ttaagttcta tttaagatta gatgtgtata ctataatcat taaataaaga cctcctaata
    59101 ttatttgaaa cagataacac tgaattagtt tgaatttgat tttcatctaa tatctttatt
    59161 taatgaactc ctaaactttt tcataataat ctccttcaaa agtcgcctgt atgggtggct
    59221 tttattttat cattcatgat ataatagaag caaacggagg acggaaaatg gtaaaagtac
    59281 gattgtattt ggtacgtcat ggcaagacca tgtttaacac gattggtcgc gcgcaaggtt
    59341 ggagcgatac tcccttaact gctgaaggtg aacgagggat tcaagagtta ggaatcggtt
    59401 tgcgagaatc tgatctacag tttgagcgcg cttattcgag tgattctggt cgtaccattc
    59461 agaccatggg aattatcctt gaagaacttg gcttgcaggg gaaaatccct tatcgcatgg
    59521 acaagcgtat cagagaatgg tgtttcggta gttttgatgg agcctatgat ggcgatcttt
    59581 tcatgggcat tattcctcgt atctttaatg tggaccacgt tcaccaattg tcttatgctg
    59641 aactggctga gggcttggta gaggtcgata cagctggttg ggctgaaggc tgggaaaaac
    59701 tcagtggccg aatcaaggaa ggctttgaaa tgattgcaaa agaaatggaa gatcaaggtg
    59761 gaggtaacgc ccttgttgtc agccatggaa tgactattgg aaccattgtt tatctgatta
    59821 atggcatgca tccgcatggt ctagataatg gtagcgtgac gattcttgaa tatgaggacg
    59881 gtcagtttag ggttgaagtt gtcggtgacc gtagttaccg agagctagga cgtgagaaga
    59941 tggaagaagg ctctatttaa tcagtctaga cttgcttgcc atgagctagg gatttgataa
    60001 gaatatcaag ataagaaaaa acagccgagg gtactccttt cggctgtttt tgatgtggaa
    60061 aactaaagtg taatgctatt gcttttagag attttcataa acaagagcaa ggaacctact
    60121 gttagaacag tcaggatagt tgacaaggct gcggctacac cgtaatttcc tctgagaacc
    60181 tctgtataaa tagctacagt cattgttctt gttttgacat tgtagaggag gatagaagta
    60241 gagagttttg aaatcattgt gacccaagat aagatggctc cagaaatgat accagatagc
    60301 atcattggag ttgtaatctt agcaaaggta ttgagacgac tacttcctaa gctttcagca
    60361 gcttcttcaa tacttggtgc tatttgttgt aagctagcaa cagatgagcg aatagtataa
    60421 ggtaatcttc tgacagatag agacataatc aagatgaaag cagtccctgt aatcataaga
    60481 aatccacttc caaatagacc agtattgaag gaagaaatga aggcaatccc tagaacggtt
    60541 cctggtacaa tataaggtac catactgagg ctgtcaatta agtttgtaaa caaattccgt
    60601 tttctaacgg ctaggtagga gataaatgtc gcaaatagaa caactagaac taaggcaatc
    60661 aaagggatac gaatggtatt gaaaatagca gatcccatac gattgaaagc tagcttgtaa
    60721 ctgtttggag aataaccttt aacaaatacc atacctgatg tttttaggaa agaggtataa
    60781 attaagtaga tttgaggtaa aatatagata aagataattc cgtagactgt tgcataaatg
    60841 gcagccattt ttccttttgt agttttttta ggctcaattg gatggagcgg attcatgctg
    60901 aaactgtagc ggtttgcaat gtgtttttgg ataaggaaaa ttgccaaggc aatgataatc
    60961 gccataattg caaaagcaga atttcctcca acctcgctaa taaattgggt ataaatcagg
    61021 acagggaaag tccgatatcc ttcgccaatc aacataggcg ttccaaagtc tgagaatgct
    61081 ctcataaata caagcaagga gctgctagta aggttggaac taggagaggt aaaacaaccg
    61141 ttacgatagg tttaaatccg aaggacccca tgctttcagc tgcttcaagt agagaattgt
    61201 caatactgtt cattgttcca gcaacatata gaaataccag tgggaatagt tgcagtgtaa
    61261 agacaagtat aattcctttg aatccataaa tatcgatagc tggaagatga agggcatttg
    61321 tcaaaaattt agtgatgacc ccatttcgtc ctagcaagag aatccaggag taggctccta
    61381 cgaaaggagc tgacatggaa gcaatgataa tcaatatttg tagaaatttc ttccccttga
    61441 agtcatacat agagaagaga taagctaata gggttcctac aactaaggaa gtgacagtag
    61501 cggtaatgga aaccctgaaa ctgttgacta gtgtctcaga gtagtaggtt ttactaaaga
    61561 aagtgacaaa attagctagt gagaattatc cttcatgtat aagtgcttac ttgagcacgg
    61621 taacgatagg ataaacgaga aagacaagat aggtaagaaa gatgaagaaa gaggaggctg
    61681 tccaaatatt tagtttttta cgttccatgg ttgactcctt ttatcaggtt ttgggaacca
    61741 tctgcagaaa agatgtttaa tttttgcgta ttgattcgta gacgaatacg attgtctttt
    61801 tgtagatctt cttcaaaagt tgattcttca ctaacttgaa tttttgaggc aaaacctgtc
    61861 tcaatgaaat actccgtatt tagtccaaga tagacgctat cgctaatagt tccttcgata
    61921 tctccagatt catctttgat aaactcttcg ggacgaatgc ttacatgaat agcttgctcc
    61981 tcaacctgat caagagctag cattcgaagg gcatagccat ctgaaaagac gatataagcg
    62041 ccgtcgctcc gtttttcaag attggcaggg ataatatttg tgcgtccgat aaaggttgcc
    62101 acaaactcat tagctggttt atgatagagt tcttttggtc ggccgatttg ttggatcacc
    62161 ccatctttca taacagcaat ttggtctgaa atagccatgg cttcttcttg gtcgtgggtt
    62221 acataaacag ttgtaattcc cacttcgtgt tggatttctc ggatggtttg acgcatatcc
    62281 aagcgaagtt tggcctccag attactaagt ggctcgtcca tgaggagaac acttggatta
    62341 accgctaagg cgcatgccaa ggtgacacgt tgttgttgtc caccactgag tttatcgggc
    62401 tttcgatccg catattgagc aatttgcatg agttcaagat acttgttggt ctgttgaatc
    62461 aattcttctt ttggaacctt cttttgcata agaccaaaag caacgttgtc tcggacagtc
    62521 aaatgtggga aaatagcgta gttttggaaa accagcccga tattgcgttt gctgggttcc
    62581 atattattga tttttgtatc atcgaagtaa aattctccat ctttgatact gttgaaacct
    62641 gcaatcatac gaagaagggt cgttttccca catcctgaag ctccaagaag ggtaaagaga
    62701 cttccttttg gaattgtaat gttcaaattc tcaataacag ggacatcgtg gtagattttt
    62761 ttggcgttaa taatttcgat ctcactcata gtgaacctct tttactgttt agattggata
    62821 tctgtaaaga cttcgttgta tttcttaacg atatctgatt tattcttgat gacataatca
    62881 taatcttaag tgagtgtttt gattttgtca attggtttca tgttttcgct tgttttagca
    62941 tttttacgaa caggacggtt agtagtggtt gtaccaagtg tatcttgtac ttcttgagag
    63001 ataataaaat cgataaattt cttggcattt tccatatttt tagatttttt aacgatagca
    63061 gcactagcag gtaggaagac ggttccttct tttggataga ctaccttaat gttagctccg
    63121 tcatttaaga gtttaactgc tggatcttca taagagagac caacagtcat ttctccatca
    63181 gcgactgctt tatagacacc agatgaactt gaaccgattt tatagtatat tgaaactaga
    63241 atagtacaca tctacttcta aaacattgtt agaaatcgat ttgactgtcc tgattaattt
    63301 gtcctgttct tatttcattt cactatgcca tcaataagtg tgaaaagatc ttttacataa
    63361 gaccaagcct tatcatcttt gtaaccacct tgagcttgta gcatatttgt taattgagca
    63421 aaggcgctag aagagtttgc tgggtcagca gttgcgattt ttccttttag ttcaggtttg
    63481 agaagatcgt tatatccttc gatgttcatg cctttagtta aatcagggtt gacgattaaa
    63541 acactaccat ctagtgtata aggagtagag tagccagttg tgttttgata ttctttgata
    63601 acattatcat tttcttttga aatatagttt tcaaagagtt ctccgtgggt agcatattgt
    63661 gtataagaac caccaaagat aatatcagct acaggaactt ctttttctga ctctagtttt
    63721 ttgaaaagtt ctccagtacc agcttgaatc agttctattt tgataccata tttttcttca
    63781 aaggcaggaa tagttgctcc aattaagccc tctgagtttg gtcaataaac gactagcgaa
    63841 ccgccgtctc ctttatcaga tgaactgtca tcggcagatt cattagaaga acaagcagca
    63901 taatacatcc atttcttttt catgatggat acctccgttg tgttatttaa gtttatttta
    63961 aaacaatgta agcgttttta aaacctacaa ttctattcta tagtatattg aatctataac
    64021 agtacacttt aactgctaaa atatttctat aaattaattt gactttcctg atagagatgt
    64081 ttacatctta tttcaattcg ctatattaga gtaaaattct ctacaaaaag aagaatagcc
    64141 tattttacta ttcttccgag tgatttcaat ttctttgggg aaatatggag atacttttta
    64201 aatactttgg caaaatattt atagtctgaa aatccaactt ggtcagagat agcgcttaaa
    64261 gaggagttgg gagattcagc catcttatct atagcttgtt tcaggcgata ttgtaagata
    64321 tattcattta gagtcatggg gaagtcttct ttgataacct tatatagatg cttgttatct
    64381 gcaaatagct agagcatttc aaggaaataa actagaaata acaattaata tggtggttca
    64441 gaaatacctt ttgataatca ataagatctt caggatgaag tgcgttgatt ccatccattt
    64501 catatttccg atttaataaa cgatatttgt tttcaccaaa ttgatgaaaa gggagtagtt
    64561 gaacttggtc gatatttaat gagttaaata gagtagcgaa tttttctgca tcctctaaac
    64621 tattgttaaa attaggaata actgggattc ttaaaacgat agttttattt tgagaaaaag
    64681 cataatgaat gtttttaata atcatttgat taaaaacccc agtcactttt ttatgtttta
    64741 tagaattata atgttttagg tctgtgtaga taaaatccac atattgaatt aaatcgataa
    64801 atttttcatg atcaacaaag gcagtagttt caatggcagt gtgtatgtga tgttctttag
    64861 ctgattttaa gatggcttta gcaaattcaa actgagcaaa tatttcacct cctgataaag
    64921 ttaaacctcc accggattct tcgtaaaatt ctttgtcttt taatacctct gtaataattt
    64981 cttctacagt cttttcttca ccgactaagg tgaatttctc tcgttgagca tctttcattt
    65041 tttcaggttt cattctttga gattcaggat tagaacacca tggacagcgc agaggacatc
    65101 cttttaaaaa aacagttgta cgaatacccg ggccgtcatg aattgaaaag tgttgaatat
    65161 taaaaataat tcctttagat atttccataa gagttcctcc tcttcataag tctatcctat
    65221 cacaaaaacg aaagaaaaac aattacgaac gaaaggttaa tttgttgttt tttgcttttt
    65281 attttggtag aataaaacgg aggtgtaaaa tgaaaagatt ggaacaaatt attaaattag
    65341 tatcagaata tgaaaagatc gacgttaata cattatcgga aaaattaaat gtatcgaaag
    65401 taacgattag aaaagattta gataaattag agtcaaaagg tttattacac agagagcatg
    65461 gatatgctgt attaaatagt ggagatgact taaatgtacg tttgtcaatt aattatgaaa
    65521 ttaagagaaa aattgttcag gaagcagtaa aattggtgtc agataatgaa acaataatga
    65581 tagaatctgg atcgacctgt gctttacttg ctgaggaaat ttgcaagcaa aaaagaaatg
    65641 ttacgattgt aacaaattca ttttttatag caaattttgt gagagcttat gattcatgtc
    65701 gtattattgt tcttggtgga gagtttcaga aggattcaca ggttactgtg ggacctttat
    65761 taaaagaaat gatacagact tttcatgtgc atcaagcttt tgttgggaca gatggttacg
    65821 ataaagagat gggctttaca ggaaaagatt taatgcgcag tgaggtagtt caatatattt
    65881 cagcagcgtc ggataaagtc attgtcctaa ctgactcaag taaatttgat aaaaggggta
    65941 cagtaagaag atttgcttta agtcaagtct atgaagtaat aacagacgaa aaactttcta
    66001 aacaaaatat agctacatta gaaaatgctg ggataatggt taaggtagtt tcgtaagagg
    66061 ttaagtgtat gaatcaagat aggaataaac tgctctctaa aattgcttat ctgtattata
    66121 ttgaaaactt aaatcagtca caaatagcag caaaattagg aatttataga acctctatta
    66181 gtagaatgtt aacagaagca aggaatgcag gaattgttaa aattgaaata gagaattttg
    66241 ataccaatat gtttaagttg gaaaattatg taaaagaaaa atatggtctg gaaagtttag
    66301 aaattattcc aaatgaattt gatgataatc caacaatttt atctgaaaga atttctcaag
    66361 ttgcagcagg tgtccttagg aatctaattg atgataatat gaaaattggc ttttcttggg
    66421 ggaaaagttt aagtaattta gtagatttaa ttcacagtaa aagtgtccga aatgttcact
    66481 tctatcctct agcaggtggt cctagtcaca tacacgctaa ataccatgtg aatacactga
    66541 tttatgaaat gtctagaaaa tttcatggag agtgtacatt tatgaatgca acgattgtgc
    66601 aagaaaataa attgttagca gatggtattt tgcaatcaag atattttgaa aatttgaaaa
    66661 atagttggaa agatttagat atagctgtag tcggaattgg tgattttagc aataaaggaa
    66721 agcatcaatg gttagacatg cttacagagg atgactttaa agaattgacc aaagttaaaa
    66781 ctgtaggaga aatttgttgt cgattttttg attcaaaagg taaagaagtc tatgaaaact
    66841 tacaggaaag aacgatagca atctctttgg aagatttaaa aaatattcct caaagtttag
    66901 ctgttgctta cggtgatacg aaagtatctt cgattctttc tgtcttgcgt gctaatttag
    66961 taaatcattt gattacagac aaaaatacaa ttttaaaagt tttggaagaa gatggggatt
    67021 tgacttttag agagattcta ggtgagtgaa aatgatagac tgattcagtt tatcgttttt
    67081 ctttttagtt gattgcacat ttgtgcttat ataaacaaaa atagtttatc tgttgttttt
    67141 ggattgacaa ctttattatg tagttgtatt ctatagttac aaaagaaaat tttaaaattt
    67201 caaatgaaaa aagcttttta catagtgaaa tgaggaggaa tttatggaaa ttattgttcc
    67261 agatcaaatt atcatgggtt taattttata tgctggcgat gcgaaacaac atatttataa
    67321 agcattagat tacataaaga acggtacatg tgaacgatgt gaagaagaaa tccagttagc
    67381 tgatgcagcc ttattagaag ctcataatct acaaacaaaa ttcttggcac aggaagcgtc
    67441 tggtacaaag acagaaatta cagctctctt tgttcattca caagatcatc tcatgactag
    67501 tatgacggag attaatttaa tcaaagaaat tattagtttg agaaaagaac ttcataaaaa
    67561 ataatactag agtattatca ttgttattaa catagaggag gaaaacataa tggtgaagat
    67621 tggtttgttt tgtgcagcag gtttttctac tggtatgctt gtaaataata tgaaaattgc
    67681 agcgcaatct agtggagttg aggcagaaat agaggcgttt tctcagtcta aattagcgga
    67741 ttatgcgcca aatatagatg ttgcactatt gggtccacaa gttgcttata cattagataa
    67801 atcaaaagaa atttgtgata agtgtgatgt tccgatagct gttattccga tgatggacta
    67861 tggtatgtta gatgggaaaa aagtattaga tttggcccta tctttgatta gtgggtaaga
    67921 aaaggagatt tattatgtca aagatggatg ttcagaaaat cattgcaccg atgatgaagt
    67981 ttgtgaatat gcgtggcatt atagctctaa aagatgggat gttagcaatt ttgccattga
    68041 cagtagttgg cagtttgttc ttgattatgg gacaattgcc gttcgaagga ttaaataaga
    68101 gcattgctag tgtttttgga gctaattgga cagagccgtt tatgcaagta tattcaggaa
    68161 cttttgctat tatgggtcta atttcttgtt tttcaattgc ctattcttat gctaagaata
    68221 gcggagtaga ggctttacca gctggagttc tatctgtatc tgcattcttt attttgctaa
    68281 gatcatctta tatccctaaa caaggtgagg cgattgggga cgctattagt aaagtttggt
    68341 ttggaggcca aggaattatc ggtgctatca ttataggttt ggtagtagga agtatttata
    68401 ccttctttat aaagagaaaa attgttatta agatgccaga acaagttcca caagctattg
    68461 ccaaacagtt tgaagcaatg attccagcat ttgtaatttt cttatcttct atgattgtat
    68521 atattttagc gaagtcattg actaatggcg gaacattcat agaaatgatt tattctgcta
    68581 ttcaagttcc gttgcaaggt ttaactggat ctttgtatgg tgctattgga attgcattct
    68641 ttatatcatt tttgtggtgg tttggtgttc atgggcaatc ggtagtaaat ggagtagtga
    68701 cagctctgct tttatctaat cttgacgcta ataaagctat gttagcctct gctaatctat
    68761 cattagaaaa tggtgcacat attgttactc aacaattttt agattcattt ttaattctat
    68821 caggttcagg gattacgttt ggtcttgtag ttgccatgct ttttgcagca aaatcaaaac
    68881 aataccaagc cttaggaaaa gttgcagctt ttccagcaat atttaacgta aatgagccag
    68941 ttgtatttgg atttccgatt gtcatgaatc cagttatgtt tgtacctttc attcttgttc
    69001 ctgtacttgc agctgtgata gtatatggag ctattgcaac aggtttcatg cagccattct
    69061 caggggtaac attgccttgg agtacaccag ctattctatc aggatttttg gtgggtggat
    69121 ggcaaggtgt tgtgactcag ttattagtat tggtgatatc tacagtggtt tactttccat
    69181 tctttaagat acaagatcgt ttagcttacc aaaatgaaat caaacaatct tagaggtatt
    69241 tgtgtgttac tgttaaactc acacatttgt gctaaaaatt agagagttaa aatttttcta
    69301 gttaaaagct tgaaaatttc tataaaaatc ggtattatat tttcgaaaga aataaaaata
    69361 ttttcgaaag aaaggtgctt acgatggtaa atacagaagt agcaagaaca acaatcaaga
    69421 cagaatattt tggcagcctt actgaaagga tgaacaaata tcgagaagat gttttaaata
    69481 aaaaacctta tattgatgct gagagagcag ttctagcaac acgcgcctat gaacgataca
    69541 aggaacaacc taatgtccta aaacgtgcat atatgctgaa agaaattttg gaaaatatgt
    69601 ctatctatat tgaagaagaa tctatgattg cgggaaatca agcttcttcc aataaagatg
    69661 ctcctatttt tccggaatat acgctagaat ttgttctcaa tgagttggat ctttttgaaa
    69721 agcgtgatgg agatgttttc tatattacag aagaaacaaa agaacaactt agaagtattg
    69781 ctccgttttg ggaaaataat aatttacgtg ctagagctgg tgccttatta cctgaagaag
    69841 tgtcagttta tatggaaaca ggattcttcg gtatggaagg taagatgaat tctggagatg
    69901 ctcacttagc agttaactat cagaaacttt tgcaatttgg tttaagaggt tttgaagagc
    69961 gggctcgtaa agcaaaagta gctctagatt taacagatcc agcaagtatt gataaatatc
    70021 atttttacga ctctatattt atcgtaatcg atgctattaa agtatatgca aagcgctttg
    70081 ttgctcttgc taaaagttta gccgaaaatg caaatcctaa acgtaagaaa gaattacttg
    70141 agattgcaga tatttgctct agagtcccat atgaaccggc aactactttt gcagaagcta
    70201 ttcaatcagt ttggtttatt caatgtattt tacaaattga atctaatggc cactctcttt
    70261 catatggccg ttttgatcaa tatatgtatc catatatgaa ggctgattta gaaagtggta
    70321 aagaaacaga agatagcatt gttgaacgtc tgacaaatct ttggattaag acaattacaa
    70381 ttaataaggt tcgcagtcaa tcacatacat tttcttcagc aggaagtcct ttatatcaaa
    70441 atgttacaat tggtggacag actcgagata agaaggatgc tgttaaccca ttatcttatt
    70501 tggtattaaa atcagttgca caaacccatc taccgcaacc taatctaact gtacgttacc
    70561 atgcaggttt agatgctcgt ttcatgaatg agtgtattga agtgatgaaa cttggttttg
    70621 gtatgcctgc atttaataat gatgagatta ttattccttc ttttattgca aaaggagtat
    70681 tggaagatga tgcttatgat tacagtgcca ttggatgtgt tgaaacggca gttccaggga
    70741 aatggggcta tcgttgcaca ggtatgagtt atatgaactt ccctaaggtt ctacttatca
    70801 cgatgaatga tggaattgat ccggcttcgg gtaaacggtt tgcaccaagc tttggtcatt
    70861 ttaaggatat gaagaacttt tctgaattag aaaatgcttg ggataaaaca ctaagatatt
    70921 tgacacgaat gagtgttatt gttgaaaatt ctattgattt atcattggaa cgagaagttc
    70981 ctgatattct atgttcagca ttgactgatg attgtattgg tcgtggaaaa caccttaaag
    71041 aaggtggagc agtatatgat tatatatcag gattgcaagt tggaattgca aatttgtcgg
    71101 attcgttagc tgcaattaaa aaattggtgt ttgaggaaga acgtataagc ccaagtcaac
    71161 tttggcatgc actggaaaca gattatgccg gagaagaagg taaggtcatt caagaaatgt
    71221 tgattcatga tgcacctaag tatggtaatg atgatgatta tgctgacaaa ttggttactg
    71281 ctgcttatga catttatgtt gatgaaattg ctaaatatcc taatacacgt tatggaagag
    71341 ggcctattgg aggaattcgt tattcaggaa catcttctat ctcagccaac gtagggcagg
    71401 gacgtggaac attagcaact ccagatggac gcaacgcggg tacaccgtta gcagagggtt
    71461 gttcaccatc acataatatg gatcaacacg gccctacatc tgttttaaaa tctgtttcaa
    71521 aattaccaac agatgaaatc gtaggtgggg ttctcttaaa tcagaaagta aatcctcaaa
    71581 cgttagccaa agaagaagat aaattaaaac taattgcttt gttacgaaca ttctttaatc
    71641 gtttacatgg gtaccatatt caatacaatg ttgtttccag agagacgttg attgacgctc
    71701 agaaacatcc tgaaaaacac agagacttaa ttgttcgtgt tgcaggatac tctgcattct
    71761 tcaatgttct ttctaaggca acccaagatg acattatagg acgtactgag cattctttgt
    71821 aaaataaaga ggttcttttt atggaattta tgcttgacac attaaattta gatgagatta
    71881 aaaagtggtc tgaaattttg ccgctagctg gggtaacttc aaatcccact attgcaaaaa
    71941 gagagggttc tattaatttt tttgaacgaa tcaaagatgt aagagaattg attggctcta
    72001 caccctctat tcatgttcag gtgatttctc aagattttga aggcatctta aaggatgctc
    72061 atgaaattcg aagacaagca ggagatgata tatttatcaa agtacctgtt actccagctg
    72121 gattacgtgc aataaaggtg ctaaaaaaag agggctacca tatcactgca acagctattt
    72181 atacagttat tcagggatta ttagctatcg aagtaggagc ggattaccta gctccatatt
    72241 ataatagaat ggaaaatctg aacattgatt caaattctgt cattcgtcaa ttagctcttg
    72301 ctattgatag acagaactct cctagtaaga ttttagctgc atcctttaaa aatgtagcac
    72361 aagtaaataa tgctttagct gcaggtgcgc atgctgttac agcaggagca gatgtttttg
    72421 aatcagcttt cgccatgcca tctatccaaa aggcggttga tgatttttct gacgattggt
    72481 ttgttactca aaatagtcgt tccatttaga tagagaggaa atacatatga gaatttttgc
    72541 tagtccttct agatatattc agggggaaaa tgccttgttt gaaaatgcca aatcaatttt
    72601 ggatttggga aattacccga ttctattatg cgatcagttg gtttatgata ttgttggaaa
    72661 acgatttgaa gattatctac ataggtatgg tttccatatt gttctggcgc tatttaatgg
    72721 tgaagcttct gacaatgaaa tcaatcgagt tgttgccttg gctgagaaag aaaattgtga
    72781 tagtattatc ggtcttggtg ggggaaagac gattgatagc gcaaaagcta ttgcagattt
    72841 gattgaaaag cctgttatta ttgctccaac aattgcatcg accgacgcac ctgtatctgc
    72901 tttatctgtt atttatacag atgaaggtgc atttgatcat tatctatttt attctaaaaa
    72961 tccagattta gttttggttg atacaaaagt tatttcacaa gcccctaagc gtttattagc
    73021 gtctggtatt gcagatggtt tagcaacttg ggttgaggcg cgtgcggtta tgcaggcaaa
    73081 tggaaaaact atgttgggac aacagcaaac attggctgga gttgcaattg cgaagaaatg
    73141 tgaagaaacg ctgtttgcag atggtttaca ggctatggca gcttgtgaag ctaaagtggt
    73201 gacaccagca ttagaaaata ttgttgaagc taatacttta ttgagtggcc taggttttga
    73261 aagtggagga ttagctgcgg cgcatgcaat tcataatggt tttactgcat tgacaggcga
    73321 cattcatcat ttaacacatg gtgaaaaagt agcttatgga actttagtac aactattatt
    73381 ggaaaataga cctaaagaag aacttgataa gtatattgag ttttacaaaa aaattggtat
    73441 gccaacaact ctaaaagaaa tgcatttgga tcaagttgga tatgatgatt taataaaagt
    73501 tggtaaacaa gcaactatgg agggtgagac aattcatcag atgccgttta agatttcgcc
    73561 ttcagatgtt gctcaagcta ttatcgctgt agatgcctat gtaaattcaa aataaacaat
    73621 aaggactact gttttccaaa tggtagtctt ttattgatcc tcgtattgaa t
//
LOCUS       DBEJAU010000004        68416 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC323 isolate 683620
            SAMN38261939-rid24807223.denovo.004, whole genome shotgun sequence.
ACCESSION   DBEJAU010000004 DBEJAU010000000
VERSION     DBEJAU010000004.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261939
            Sequence Read Archive: SRR26833919
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 68416)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 68416)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576303.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576303.1
            Genome Coverage       :: 154x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/19/2025 01:05:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,121
            CDSs (total)                      :: 2,078
            Genes (coding)                    :: 1,943
            CDSs (with protein)               :: 1,943
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 36
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 72 of 135
            Pseudo Genes (incomplete)         :: 63 of 135
            Pseudo Genes (internal stop)      :: 51 of 135
            Pseudo Genes (multiple problems)  :: 46 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..68416
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261939-rid24807223.denovo.004"
                     /strain="GPSC323"
                     /isolate="683620"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            complement(<1..1970)
                     /gene="pfbA"
                     /locus_tag="ACL29Z_000315"
     CDS             complement(<1..1970)
                     /gene="pfbA"
                     /locus_tag="ACL29Z_000315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010976622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multi-ligand-binding adhesin PfbA"
                     /protein_id="HGR0068686.1"
                     /translation="MLKIVKKLEVLMKYFVPNEVFSIRKLKVGTCSVLLAISILGSQG
                     ILSDEVVTSSSPMATKESSNAITNDLDNSPTVNQNRSAEMIASNSTTNGLDNSLSVNS
                     ISSNGTIRSNSQLDNRTVESTVTSTNENKSYKEDVISDRIIKKEFEDTALSVKDYGAV
                     GDGIHDDRQAIQDAIDAAAQGLGGGNVYFPEGTYLVKEIVFLKSHTHLELNEKATILN
                     GINIKNHPSIVFMTGLFTDDGAQVEWGPTEDISYSGGTIDMNGALNEEGTKAKNLPLI
                     NSSGAFAIGNSNNVTIKNVTFKDSYQGHAIQIAGSKNVLVDNSRFLGQALPKTMKDGQ
                     IISKESIQIEPLTRKGFPYALNDDGKKSENVTIQNSYFGKSDKSGELVTAIGTHYQTL
                     STQNPSNIKILNNHFDNMMYSGVRFTGFTDVLIKGNRFDKKVKGESVHYRENGAALVN
                     AYSYKNTKDLLDLNKQMVIAENIFNIADPKTKAIRVAKDSAEYLGKVSDITVTKNVIN
                     NNSKETEQPNIELLRVSDNLVVSENSIFGGKEGIVIEDSKGKITVLNNQFYNLSGKYI
                     SFIKSNANGKEPVIRDSDGNFNIVTENGLYKIVTNNLSDKNEKEKNKEEKQSNSNNVI
                     DSNQKNGEFNSSKDNRQMNDKIDNKQDNKTEEV"
     gene            complement(3100..4326)
                     /locus_tag="ACL29Z_000316"
     CDS             complement(3100..4326)
                     /locus_tag="ACL29Z_000316"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001134527.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegT/DnrJ/EryC1/StrS family aminotransferase"
                     /protein_id="HGR0068687.1"
                     /translation="MPNYNIPFSPPDITEAEIAEVADTLRSGWITTGPKTKELERRLS
                     LYTQTPKTVCLNSATAALELILRVLEVGPGDEVIVPAMTYTASCSVITHVGATPVMVD
                     IQADTFEMDYDLLEQAITEKTKVIIPVELAGIVCDYDRLFQVVEKKRDFFTASSKWQK
                     AFNRIVIVSDSAHALGSTYKGQPSGSIADFTSFSFHAVKNFTTAEGGSATWKANPVID
                     DEEMYKEFQILSLHGQTKDALAKMQLGSWEYDIVTPAYKCNMTDIMASLGLVQLDRYP
                     SLLQRRKDIVDRYDSGFAGSRIHPLAHKTETVESSRHLYITRVEGASLEERNLIIQEL
                     AKAGIASNVHYKPLPLLTAYKNLGFDMTNYPKAYAFFENEITLPLHTKLSDEEVDYII
                     ETFKTVSEKVLTLSKK"
     gene            complement(4369..5061)
                     /locus_tag="ACL29Z_000317"
     CDS             complement(4369..5061)
                     /locus_tag="ACL29Z_000317"
                     /EC_number="2.7.8.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000922225.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016740 - transferase activity [Evidence
                     IEA];
                     GO_process: GO:0006486 - protein glycosylation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sugar transferase"
                     /protein_id="HGR0068688.1"
                     /translation="MLKWEDLPVEMKSSEVESYYQLVSKRKGSLIFKRCLDWVLALVL
                     LVLTSPIFLILSIWIKLDSKGPVIYKQERVTQYNRRFKIWKFRTMVTDADKKGSLVTS
                     ANDSRITKVGNFIRRVRLDELPQLVNVLKGEMSFVGTRPEVPRYTEQYSPEMMATLLL
                     QAGITSPASINYKDEDTIISQMTEKGLSVDQAYVEHVLPEKMRYNLAYLREFSFFGDI
                     KIMFQTVFEVLK"
     gene            complement(5234..6985)
                     /locus_tag="ACL29Z_000318"
     CDS             complement(5234..6985)
                     /locus_tag="ACL29Z_000318"
                     /EC_number="7.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001180175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGR0068689.1"
                     /translation="MQNKQEQWTVLKRLMSYLKPYGLLTFLALSFLLATTVIKSVIPL
                     VASHFIDQYLSNLNQLAVTVLLVYYGLYILQTVVQYVGNLLFARVSYSIVRDIRRDAF
                     ANMEKLGMSYFDKTPAGSIVSRLTNDTETISDMFSGILSSFISAVFIFLTTLYTMLVL
                     DFRLTALVLLFLPLIFLLVNLYRKKSVKIIEKTRSLLSDINSKLAENIEGIRIIQAFN
                     QEKRLQAEFDEINQEHLAYANRSVALDALFLRPAMSLLKLLGYAVLMTYFGYRGLSIG
                     ITAGTMYAFIQYINRLFDPLIEVTQNFSTLQTSMVSAGRVFALIDERTYEPLQENGQA
                     KVKEGNIRFEHVCFSYDGKHPILDDISFSVNKGETIAFVGHTGSGKSSIINVLMRFYE
                     FQSGRVLLDDVDIRDFSQEELRKNIGLVLQEPFLYHGTIKSNIAMYQEISDEQVQAAA
                     AFVDADSFIQELPQGYDSPVSERGSSFSTGQRQLLAFARTVASQPKILILDEATANID
                     SETESLVQASLAKMRQGRTTIAIAHRLSTIQDANCIYVLDKGRIIESGTHEELLTLGG
                     TYHKMYSLQAGAMAYTL"
     gene            complement(6975..8720)
                     /locus_tag="ACL29Z_000319"
     CDS             complement(6975..8720)
                     /locus_tag="ACL29Z_000319"
                     /EC_number="7.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000022567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGR0068690.1"
                     /translation="MSIIQKLWWFFKLEKRRYLVGIVALILVSVLNLIPPMVMGRVID
                     AITSGQLTQQDLLLSLFYLLLAAFGMYYLRYVWRMYILGTSYCLGQIMRSRLFKHFTK
                     MSSAFYQTYRTGDLMAHATNDINALTRLAGGGVMSAVDASITALVTLLTMLFSISWQM
                     TLVAILPLPFMAYATSRLGRKTHKAFGESQAAFSELNNKVQESVSGIKVTKSFGYQAD
                     ELKSFQAVNELTFQKNLQTMKYDSLFDPMVLLFVGSSYVLTLLVGSLVVQEGQITVGN
                     LVTFISYLDMLVWPLMAIGFLFNTTQRGKVSYQRIENLLSQESPVQDPEFPLDGIENG
                     RLEYAIDSFAFENEETLTDIHFSLAKGQTLGLVGQTGSGKTSLIKLLLREYDVDKGAI
                     YLNGHDIRDYRLTDLRSLMGYVPQDQFLFATSILDNIRFGNPNLPLSAVEEATKLARV
                     YQDIVDMPQGFDTLIGEKGVSLSGGQKQRLAMSRAMILDPDILILDDSLSAVDAKTEY
                     AIIDNLKETRKDKTTIITAHRLSAVVHADLILVLQNGQIIERGRHEDLLALDGWYAQT
                     YQSQQLEMKGEEDAE"
     gene            complement(8926..9303)
                     /locus_tag="ACL29Z_000320"
     CDS             complement(8926..9303)
                     /locus_tag="ACL29Z_000320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000825490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DUF421 domain-containing protein"
                     /protein_id="HGR0068691.1"
                     /translation="MKRLIDGKPTLLIKNGNIDPEACRSVGLSASDVSLKLRSQGIFQ
                     MKQVKRAVQEQNGQLIVVQMGDENPKYPVVTDGVIQVDVLESIGRSEEWLLDNLSKQG
                     HDNVANIFIAEYDKGAVTVVTYE"
     gene            complement(9375..9831)
                     /locus_tag="ACL29Z_000321"
                     /pseudo
     CDS             complement(9375..9831)
                     /locus_tag="ACL29Z_000321"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730499.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3290 family protein"
     gene            9965..10792
                     /locus_tag="ACL29Z_000322"
     CDS             9965..10792
                     /locus_tag="ACL29Z_000322"
                     /EC_number="3.1.11.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006596696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004518 - nuclease activity [Evidence
                     IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease III"
                     /protein_id="HGR0068692.1"
                     /translation="MKLISWNIDSLNAALTSDSARAKLSQEVLQTLVAENADIIAIQE
                     TKLSAKGPTKKHVEILEELFPGYENTWRSSQEPARKGYAGTMFLYKKELTPTISFPEI
                     GAPSTMDLEGRIITLEFDAFFVTQVYTPNAGDGLKRLEERQVWDAKYAEYLAELDKEK
                     PVLATGDYNVAHNEIDLANPASNRRSPGFTDEERAGFTNLLATGFTDTFRHVHGDVPE
                     RYTWWAQRSKTSKINNTGWRIDYWLTSNRIADKVTKSDMIDSGARQDHTPIVLEIDL"
     gene            10804..10899
                     /locus_tag="ACL29Z_000323"
                     /pseudo
     CDS             10804..10899
                     /locus_tag="ACL29Z_000323"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809023.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="glyoxalase"
     gene            10947..11186
                     /locus_tag="ACL29Z_000324"
     CDS             10947..11186
                     /locus_tag="ACL29Z_000324"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glyoxalase"
                     /protein_id="HGR0068693.1"
                     /translation="MLEEGTKDQLAELTYPFGRGVNLSFGIKDVPKLYQKVMEANYPI
                     YRLLTKRKFRVSDPYIYPHKFAVLDPDGYFLRFSE"
     regulatory      11569..11664
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00167"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="purine riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="guanine and/or adenine"
                     /db_xref="RFAM:RF00167"
     gene            12064..12645
                     /locus_tag="ACL29Z_000325"
     CDS             12064..12645
                     /locus_tag="ACL29Z_000325"
                     /EC_number="2.4.2.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000770427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016763 - pentosyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0043101 - purine-containing compound
                     salvage [Evidence IEA];
                     GO_process: GO:0046110 - xanthine metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="xanthine phosphoribosyltransferase"
                     /protein_id="HGR0068694.1"
                     /translation="MKLLEERILKDGHILGDNILKVDSFLTHQVDFSLMQEIGKVFAE
                     KFAATGITKVVTIEASGIAPAVFTAEALNVPMIFAKKAKNITMNEGILTAQVYSFTKQ
                     VTSTVSIAGKFLSPEDKVLIIDDFLANGQAAKGLIQIIEQAGATVQAIGIVIEKSFQD
                     GRDLLEKAGYPVLSLARLDRFENGQVVFKEADL"
     gene            12645..13907
                     /locus_tag="ACL29Z_000326"
     CDS             12645..13907
                     /locus_tag="ACL29Z_000326"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001194492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015205 - nucleobase transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nucleobase:cation symporter-2 family protein"
                     /protein_id="HGR0068695.1"
                     /translation="MQTQEKHSQAAVLGLQHLLAMYSGSILVPIMIATALGYSAEQLT
                     YLISTDIFMCGVATFLQLQLNKYFGIGLPVVLGVAFQSVAPLIMIGQSHGSGAMFGAL
                     IASGIYVVLVSGIFSKVANLFPSIVTGSVITTIGLTLIPVAIGNMGNNVPEPTGQSLL
                     LSAITVLIILLINIFTKGFIKSISILIGLVVGTAIAATMGLVDFSPVAVAPLVHVPTP
                     LYFGMPTFEISSIVMMCIIATVSMVESTGVYLALSDITKDPIDSTRLRNGYRAEGLAV
                     LLGGIFNTFPYTGFSQNVGLVKLSGIKKRLPIYYAAGFLVLLGLLPKFGALAQIIPSS
                     VLGGAMLVMFGFVSIQGMQILARVDFANNEHNFLIAAVSIAAGVGLNNSNLFVSMPTA
                     FQMFFSNGIVVASLFAIVLNAVLNHKKK"
     gene            complement(13994..14860)
                     /locus_tag="ACL29Z_000327"
     CDS             complement(13994..14860)
                     /locus_tag="ACL29Z_000327"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000815109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II restriction endonuclease"
                     /protein_id="HGR0068696.1"
                     /translation="MKQTRNFDEWLSTMTDTVADWTYYTDFPKVYKNVSSIKVALNIM
                     NSLIGSKNIQEDFLDLYQNYPEILKVVPLLIAKRLRDTIIVKDPIKDFYFDFSKRNYS
                     IEEYTMFLEKSGIFDLLQNHLVSNLVDYVTGVEVGMDTNGRKNRTGDAMENIVQSYLE
                     AEGYILGENLFKEIEQNEIEEIFSVDLSAITNDGNTVKRFDFVIKNEQVLYLIEVNFY
                     SGSGSKLNETARSYKMIAEEIKAIPNVEFMWITDGQGWYKAKNNLRETFDILPFLYNI
                     NDLEHNILKNLK"
     gene            complement(14847..15617)
                     /locus_tag="ACL29Z_000328"
     CDS             complement(14847..15617)
                     /locus_tag="ACL29Z_000328"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001810592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific DNA-methyltransferase"
                     /protein_id="HGR0068697.1"
                     /translation="MTKPYYNKNKMILVHSDTFKFLSKMKPESMDMIFADPPYFLSNG
                     GISNSGGQVVSVDKGDWDKISSFEEKHEFNRKWIRLAKEVLKPNGTVWISGSLHNIYS
                     VGMALEQEGFKILNNITWQKTNPAPNLSCRYFTHSTETILWARKNDKKARHYYNYDLM
                     KELNDGKQMKDVWTGSLTKKVEKWAGKHPTQKPEYLLERIILASTKEGDYILDPFVGS
                     GTTGVVAKRLGRRFIGIDAEKEYLKIARKRLEAENETN"
     gene            complement(15643..16497)
                     /locus_tag="ACL29Z_000329"
     CDS             complement(15643..16497)
                     /locus_tag="ACL29Z_000329"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012972462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA adenine methylase"
                     /protein_id="HGR0068698.1"
                     /translation="MKIKEIKKVTLQPFTKWTGGKRQLLPVIRELMPKTYNRYFEPFV
                     GGGALFFDLAPKDAVINDFNAELINCYQQIKDNPQELIEILKVHQEYNSKEYYLDLRS
                     ADRDERIDMMSEVQRAARILYMLRVNFNGLYRVNSKNQFNVPYGRYKNPKIVDEELIS
                     AISVYINNNQLEIKVGDFEKAIVDVRTGDFVYFDPPYIPLSETSAFTSYTHEGFSFAD
                     QVRLRDAFKRLSDTGAYVMLSNSSSALVEELYKDFNIHYVEATRTNGAKSSSRGKISE
                     IIVTNYEK"
     gene            complement(16654..17058)
                     /locus_tag="ACL29Z_000330"
     CDS             complement(16654..17058)
                     /locus_tag="ACL29Z_000330"
                     /EC_number="3.1.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000651202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016790 - thiolester hydrolase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PaaI family thioesterase"
                     /protein_id="HGR0068699.1"
                     /translation="MKDFHFDAISAFENYEIEKMRDGHVVVTTKVVNSSLNYYGNAHG
                     GYLFTLCDQISGLVVISLGLDGVTLQSSINYLKAGKLDDVLTIKGECVHQGRTTCVMD
                     VDITNQEGRNVCKATFTMFVTGQRSEERQVRI"
     gene            complement(17128..18609)
                     /locus_tag="ACL29Z_000331"
     CDS             complement(17128..18609)
                     /locus_tag="ACL29Z_000331"
                     /EC_number="2.7.7.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose--hexose-1-phosphate
                     uridylyltransferase"
                     /protein_id="HGR0068700.1"
                     /translation="MTLVDKFVTHVISESSFEEMDRIYLTNRVLARVGEGVLEVETNL
                     DKLIDLKDQLVEEAVRLETIEDSQTAREILGTELMDLVTPCPSQVNRDFWEAYAYSPE
                     QAIEDFYQLSRKNDYIKLKAIAKNIAYRIPSDYGELEITINLSKPEKDPKEIAVAKLV
                     QASNYPQCQLCLENEGYHGRVNHPARSNHRIIRFEMVGQEWGFQYSPYAYFNEHCIFL
                     DGQHRPMAISRQSFERLLAIVEQFPGYFAGSNADLPIVGGSILTHDHYQGGRHVFPME
                     LAPLQKTFRFAGFEQVKAGIIKWPMSVLRLTSDSKEDLINLADKIFQEWRQYSDSSVQ
                     ILAETDGTPHHTITPIARKRDGQFELDLVLRDNQTSAEHPDGIYHPHKDVQHIKKENI
                     GLIEVMGLAILPPRLKEEVEQVASYLVGEAVTVADYHQEWADQLKSQHPDLTDKEKAL
                     AIVKDSVGAIFVRVLEDAGVYKQTEQGQTAFMRFVEHVGISLD"
     gene            complement(18628..19806)
                     /locus_tag="ACL29Z_000332"
     CDS             complement(18628..19806)
                     /locus_tag="ACL29Z_000332"
                     /EC_number="2.7.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000047000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004335 - galactokinase activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006012 - galactose metabolic process
                     [Evidence IEA];
                     GO_process: GO:0046835 - carbohydrate phosphorylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="galactokinase"
                     /protein_id="HGR0068701.1"
                     /translation="MTQHLTAETLRKDFLAVFGQEADQTFFSPGRINLIGEHTDYNGG
                     HVFPAAISLGTYGAARKRDDQVLRFYSANFEDKGIIEVPLADLKFEKEHNWTNYPKGV
                     LHFLQEAGHVIDKGFDFYVYGNIPNGAGLSSSASLELLTGVVAEHLFDLKLERLDLVK
                     IGKQTENNFIGVNSGIMDQFAIGMGADQRAIYLDTNTLEYDLVPLDLKDNVVVIMNTN
                     KRRELADSKYNERRAECEKAVEELQVALDIQTLGELDEWAVDQYSYLIKDENRLKRAR
                     HAVLENQRTLKAQAALQAGDLETFGRLMNASHVSLEHDYEVTGLELDTLVHTAWAQEG
                     VLGARMTGAGFGGCAIALVQKDTVEAFKEAVGKHYEEVVGYAPSFYIAEVAGGTRVLD
                     "
     gene            19970..20977
                     /gene="galR"
                     /locus_tag="ACL29Z_000333"
     CDS             19970..20977
                     /gene="galR"
                     /locus_tag="ACL29Z_000333"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000212522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding transcriptional regulator GalR"
                     /protein_id="HGR0068702.1"
                     /translation="MATLKDIAQLASVSIATVSRVLNRDQSLSVTEETRHRILTVAEE
                     LGYTKHLKTGESHKPKQKIAIIQWVSEQGELDDLYYYQIRLGIEKRAQELDYDILRYF
                     NDHPFTLSEEVIGILCIGKFSRAQISAFEEYQKPLVFLDSDTLSLGHTCIITDFYTAM
                     KQVVDYFLSQGMDRIGILTGLEETTDQEEIIQDKRLENFKNYSQARGIYHDELVFQGR
                     FTAQSGYDLMKEAIQSLGDQLPPAFFAASDSLAIGALRALQEAGINLPDRVSLISYND
                     TSLTKQVYPPLSSITVYTEEMGRAGMDILNKEVLHGRKIPSLTMLGTRLTLRESTLNQ
                     E"
     gene            complement(21024..22061)
                     /locus_tag="ACL29Z_000334"
     CDS             complement(21024..22061)
                     /locus_tag="ACL29Z_000334"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000833740.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-binding dehydrogenase"
                     /protein_id="HGR0068703.1"
                     /translation="MKSAVYTKAGQVGLASIERPQIIEADDVIIRVVRACVCGSDLWR
                     YRNPETKAGHKNSGHEAIGIVEEAGEAITTVKPGDFVIVPFTHGCGECDACLAGFDGS
                     CDNHIGNNLGGDFQAEYIRFHYANWALVKIPGQPSDYTEGMLKSLLTLADVMPTGYHA
                     ARVANVQKGDKVVVIGDGAVGQCAVIAAKMRGASQIILMSRHEDRQKMAMESGATAVV
                     AERGQEGITKVREILGGGADAALECVGTEVAIEQALGVLHNGGRMGFVGVPHYNNRAL
                     GSTFMQNISVAGGAASATTYDKQFLLKAVLDGDINPGRVFTSSYKLEDIDQAYKDMDE
                     RKTIKSMIVIE"
     gene            complement(22062..22415)
                     /gene="nmlR"
                     /locus_tag="ACL29Z_000335"
     CDS             complement(22062..22415)
                     /gene="nmlR"
                     /locus_tag="ACL29Z_000335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="stress response transcriptional regulator NmlR"
                     /protein_id="HGR0068704.1"
                     /translation="MNIKSASDLLGISADTIRYYERVGLVPPITRTATGIRDFQDQDI
                     EALEFIKCFRSACVSVDSLVDYMSLYQKGDETREERLGILEEEKQKLEERLSQLQTAL
                     NRLNLKIKLYKEGKF"
     gene            complement(22659..23549)
                     /gene="czcD"
                     /locus_tag="ACL29Z_000336"
     CDS             complement(22659..23549)
                     /gene="czcD"
                     /locus_tag="ACL29Z_000336"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000645106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation diffusion facilitator family transporter
                     CzcD"
                     /protein_id="HGR0068705.1"
                     /translation="MKAKYAVWVAFFLNLTYAIVEFIAGGVFGSSAVLADSVHDLGDA
                     IAIGMSAFLETISNREEDNQYTLGYKRFSLLGALVTAVILVTGSVLVILENVTKILHP
                     QPVNDEGILWLGIIAITINLLASLVVGKGKTKNESILSLHFLEDTLGWVAVILMAIVL
                     RFTDWYILDPLLSLVISFFILSKALPRFWSTLKIFLDAVPEGLDIKQVKSGLERLDNV
                     ASLNQLNLWTMDALEKNAIVHVCLKEMEYMETCKESIRIFLKDCGFQNITIEIDADLE
                     THQTHKRKVCDLERSYEHQH"
     gene            23682..24218
                     /locus_tag="ACL29Z_000337"
     CDS             23682..24218
                     /locus_tag="ACL29Z_000337"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000181689.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HGR0068706.1"
                     /translation="MTNIDRRISKTKKAIYQAFIQLLNAKGYEATTVQDIIDLADVGR
                     STFYCHYESKELLLDQLCRYLFHHLFEREQAISTEDYLAHLFLHFQKNQDHIASLLFS
                     KNDYFLRQLQRELEHHVYPMLAADLKQTHPSLPTSYLQHFVVTNFIETLTWWLKKGQD
                     FTDQEVVQFYLDLLIPKN"
     gene            complement(24385..25191)
                     /gene="pnuC"
                     /locus_tag="ACL29Z_000338"
     CDS             complement(24385..25191)
                     /gene="pnuC"
                     /locus_tag="ACL29Z_000338"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015663 - nicotinamide mononucleotide
                     transmembrane transporter activity [Evidence IEA];
                     GO_process: GO:0015890 - nicotinamide mononucleotide
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinamide riboside transporter PnuC"
                     /protein_id="HGR0068707.1"
                     /translation="MHTYLQKKIENIKTTLGEMSGGYRRMVAAMADLGFSGTMKAIWD
                     DLFAHRSFAQWIYLLVLGSFPLWLELVYEHRIVDWIGMICSLTGIICVIFVSEGRASN
                     YLFGLINSVIYLILALQKGFYGEVLTTLYFTVMQPIGLLVWIYQAQFKKEKQEFVARK
                     LDGKGWTKYLSISVLWWLAFGFIYQSIGANRPYRDSITDATNGVGQILMTAVYREQWI
                     FWAATNVFSIYLWWGESLQIQGKYLIYLINSLVGWYQWSKAAKQNTDLLN"
     gene            complement(25536..27056)
                     /locus_tag="ACL29Z_000339"
     CDS             complement(25536..27056)
                     /locus_tag="ACL29Z_000339"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007521043.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease/substrate-binding
                     protein"
                     /protein_id="HGR0068708.1"
                     /translation="MTNLIATFQDRFSDWLTALSQHLQLSLLTLLLAILLAIPLAVFL
                     RYHEKLADWVLQIAGIFQTIPSLALLGLFIPLMGIGTLPALTALVIYAIFPILQNTIT
                     GLKGIDPSLQEAGIAFGMTRWERLKKFEIPLAMPVIMSGIRTAAVLIIGTATLATLIG
                     AGGLGSFILLGIDRNNASLILIGALSSAVLAIAFNFLLKVMEKAKLRTIFSGFALVAL
                     LLGLSYSPALLVQKEKENLIIAGKIGPEPEILANMYKLLIEENTSMTATVKPNFGTTS
                     FLYEALKKGDIDIYPEFTGTVTESLLQPSPKVSHEPEQVYQVARDGIAKQDHLAYLKP
                     MSYQNTYAVAVPKKIAQEYGLKTISDLKKVEGQLKAGFTLEFNDREDGNKGLQSMYGL
                     NLNVATMQPALRYQAIQSGDIQITDAYSTDAELERYDLQVLEDDKQLFPPYQGAPLMK
                     EALLKKHPELERVLNTLAGKITESQMSQLNYQVGVEGKSAKQVAKEFLQEQGLLKK"
     gene            complement(27049..27777)
                     /locus_tag="ACL29Z_000340"
     CDS             complement(27049..27777)
                     /locus_tag="ACL29Z_000340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HGR0068709.1"
                     /translation="MIEYKNVALCYTEKDVLRDVNLQIEDGEFMVLVGPSGSGKTTML
                     KMINRLLEPTDGNIYMDGKRIKDYDERELRLSTGYVLQAIALFPNLTVAENIALIPEM
                     KGWSKEEITKKTEELLAKVGLPVAEYGHRLPSELSGGEQQRVGIVRAMIGQPKIFLMD
                     EPFSALDAISRKQLQVLTKELHKEFGMTTIFVTHDTDEALKLADRIAVLQDGEIRQVA
                     NPETILKVPATDFVADLFGGSVHD"
     gene            complement(27791..28555)
                     /locus_tag="ACL29Z_000341"
     CDS             complement(27791..28555)
                     /locus_tag="ACL29Z_000341"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000043863.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nuclear transport factor 2 family protein"
                     /protein_id="HGR0068710.1"
                     /translation="MSQQVKNAHNLYIHAIQDGRVAEAQAQSVGDTYIQHSTGVPDGK
                     EGFAAFFADFFERHPERQIKIVRTIEDGNLVFVHVHQYLNGGEAQWVTTDTFRADENG
                     RIVEHWDVIDYYRTPENDQLDQIFGDFEIKDLDKKAENKKLVRRFLTEIFQNGELEQW
                     SDYVADDLIQHNHDIGQGSAAYKNYVAEYSVTFDFVFQLLGQGNYVVSYGQTQIDGVA
                     YAQYDIFRLENGKIVEHWDNKEVMPKVEDLTNRGKF"
     gene            complement(28559..29002)
                     /locus_tag="ACL29Z_000342"
     CDS             complement(28559..29002)
                     /locus_tag="ACL29Z_000342"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000655204.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HGR0068711.1"
                     /translation="MKDGHLLAHHIRLLNGRIFQKLLSQDPEALYRGEQGKILAVLWN
                     SETGCATATDIALATGLANNTLTTMIKKLEEQKLVIVSPCGKDKRKKYLVLTELGKSQ
                     KEVGHRVSQKLDTIFYKGFSEEEIHQFEGFQERILANLKEKGNEV"
     gene            complement(29684..29980)
                     /locus_tag="ACL29Z_000343"
     CDS             complement(29684..29980)
                     /locus_tag="ACL29Z_000343"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000230158.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0030153 - bacteriocin immunity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin immunity protein"
                     /protein_id="HGR0068712.1"
                     /translation="MVEPNLESLIKDLYNHVRHDLSEDLVAALLETTKKLPTTNEQLQ
                     AVRLSGLVNRELLLNPKHPAPELLNLASFIKREEAKYRGTATSALMYEELFKML"
     gene            complement(30002..31066)
                     /gene="pepA"
                     /locus_tag="ACL29Z_000344"
     CDS             complement(30002..31066)
                     /gene="pepA"
                     /locus_tag="ACL29Z_000344"
                     /EC_number="3.4.11.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamyl aminopeptidase"
                     /protein_id="HGR0068713.1"
                     /translation="MTTLFSKIKEVTELAAVSGHEAPVRAYLREKLTPHVDEVVTDGL
                     GGIFGIKHSEAVDAPRVLVASHMDEVGFMVSEIKLDGTFRVVEIGGWNPMVVSSQRFK
                     LLTRDGHEIPVISGSVPPHLTRGKGGPTMPAIADIVFDGGFADKAEAESFGIRPGDTI
                     VPDSSAILTANEKNIISKAWDNRYGVLMVSELAEALSGQKLGNELYLGSNVQEEVGLR
                     GAHTSTTKFDPEVFLAVDCSPAGDVYGGQGKIGDGTLIRFYDPGHLLLPGMKDFLLTT
                     AEEAGIKYQYYCGKGGTDAGAAHLKNGGVPSTTIGVCARYIHSHQTLYAMDDFLEAQA
                     FLQALVKKLDRSTVDLIKHY"
     gene            31467..32168
                     /locus_tag="ACL29Z_000345"
     CDS             31467..32168
                     /locus_tag="ACL29Z_000345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000167854.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent epimerase/dehydratase family
                     protein"
                     /protein_id="HGR0068714.1"
                     /translation="MTKTILVTGGTSYIGSHTVKALLNAGYQVHVLDNLSTGNRAAVD
                     SRASFKELDVYDASALKAYLEENQIDAVLHCAGEIVVSESIENPSKYFTANVAGMNQV
                     LKVLSEVGIQKIMFSSTASLYRNNCIDKPVTEDTLLDPVNPYAETKLMGERMIYWMAN
                     RYDWKYVIFRYFNASGAEMDASNGLRVKNPTHIIPNINKTALGQNDSLKIFGDDYDTR
                     DGSCIRDYIYVLDLA"
     gene            32184..32294
                     /locus_tag="ACL29Z_000346"
     CDS             32184..32294
                     /locus_tag="ACL29Z_000346"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001108391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose 4-epimerase"
                     /protein_id="HGR0068715.1"
                     /translation="MNYLFQEDSSSQIFNLGTKKGYTIKEIFKTAEELLN"
     gene            32591..33550
                     /locus_tag="ACL29Z_000347"
     CDS             32591..33550
                     /locus_tag="ACL29Z_000347"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000777236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HGR0068716.1"
                     /translation="MKLSHYLIGLLLLLVFLSISIGTSDFSWGKLFDFDQQTWLLFQE
                     SRLPRTISILLTASSMSMAGLLMQTITQNQFAAPSTVGTTEAAKLGMVLSLFVFPSAS
                     LTQKMLFAFVSSIVFTLFFLAFMTIFTVKERWMLPLIGIIYSGIIGSVTEVIAYRFNL
                     VQSMTAWTQGSFSMIQTHQYEWLFLGLIILITVWKLSQTFTIMNLGKETSESLGISYS
                     LLEKLALFLVALTTSVTMITVGGLPFLGVIVPNLVRKRYGDNLSQTKLMVALVGANLV
                     LACDILSRVLIRPYELSVSLLLGIIGSLVFILLLWRGGRKDAD"
     gene            33540..34496
                     /locus_tag="ACL29Z_000348"
     CDS             33540..34496
                     /locus_tag="ACL29Z_000348"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001193667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron chelate uptake ABC transporter family
                     permease subunit"
                     /protein_id="HGR0068717.1"
                     /translation="MQTKSKHTKLFWILIILAIGACLLYFWPITHLSAFAWKLRSQKI
                     IVYLLVAIATGISTISFQTLTENRFLTPSILGIESFYVLLQTLLLVFESKFLQLGKSP
                     ILEFLVLLLVQSFFFLALQGYLKTLMKQDLVFILLICLALRSLFRNISTFLQVLMDPN
                     EYDKLQNSLFASFQHLNTSILAIGSLIILALTIFFFRKAVVLDVLHLQRETAQILGLD
                     VEKEQKELLWGIVLLTSTATALVGPMAFFGFMLANLTYLIVKDYQHKLLFIVAILVGF
                     ISLTLGQALIERVFALEIRISMIIESVGGFLFFILLYRRARQ"
     gene            34493..35245
                     /locus_tag="ACL29Z_000349"
     CDS             34493..35245
                     /locus_tag="ACL29Z_000349"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000764290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGR0068718.1"
                     /translation="MKLENIDKSIQKQDILQGISLEVSPQKLTAFIGPNGAGKSTLLS
                     IMSRLTKKDQGVLSIKGREIESWNSQELAQELTILKQKINYQAKLTVEELVSFGRFPY
                     SRGRLRSEDWEKIRETLNYLELTNLKDRYINSLSGGQLQRVFIAMVLAQDTDFILLDE
                     PLNNLDIKQSVSMMQILRRLVEELGKTIIIVLHDINMASQYADEIVAFKDGQVFSKGR
                     TDQIMQADLLSQLYEIPITLADINDKKICIYS"
     gene            35341..36306
                     /locus_tag="ACL29Z_000350"
     CDS             35341..36306
                     /locus_tag="ACL29Z_000350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000858258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="siderophore ABC transporter substrate-binding
                     protein"
                     /protein_id="HGR0068719.1"
                     /translation="MKTSLKLYFTALVASFLLLLGACSTNSSTSQTETSSSAPTEITI
                     KSSLDEVKLSKVPEKIVTFDLGAADTIRALGFEKNIVGMPTKTVPTYLKDLVGTVKNV
                     GSMKEPDLEAIAALEPDLIIASPRTQKFVDKFKEIAPTVLFQASKDDYWTSTKANIES
                     LASAFGETGTQKAKEELAKLDKSIQEVATKNESSDKKALAILLNEGKMAAFGAKSRFS
                     FLYQTLKFKPTDTKFEDSRHGQEVSFESVKEINPDILFVINRTLAIGGDNSSNDGVLE
                     NALIAETPAAKNGKIIQLTPDLWYLSGGGLESTKLMIEDIQKALK"
     gene            complement(36531..36773)
                     /gene="yidD"
                     /locus_tag="ACL29Z_000351"
     CDS             complement(36531..36773)
                     /gene="yidD"
                     /locus_tag="ACL29Z_000351"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertion efficiency factor
                     YidD"
                     /protein_id="HGR0068720.1"
                     /translation="MKRILIAPVRFYQRFISPVFPPSCRFELTCSNYMIQAIEKHGFK
                     GVLMGLARILRCHPWSKTGKDPVPDHFSLKRNQEGE"
     gene            complement(36773..37495)
                     /locus_tag="ACL29Z_000352"
     CDS             complement(36773..37495)
                     /locus_tag="ACL29Z_000352"
                     /EC_number="5.4.99.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006150169.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009982 - pseudouridine synthase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pseudouridine synthase"
                     /protein_id="HGR0068721.1"
                     /translation="MRINKYIAHAGVASRRKAEELIKQGLVTVNGQVVRELATTIKSG
                     DKVEVEGQPIYNEEKVYYLLNKPRGVISSVTDDKGRKTVVDLLPNVKERIYPVGRLDW
                     DTSGVLILTNDGDFTDEMIHPRNEIDKVYVARVKGVANKDNLRPLTRGLEIDGKKTKP
                     AVYEILKVDPVKNRSVVQLTIHEGRNHQVKKMFEAVGLQVDKLSRTRFGHLDLTGLRP
                     GESRRLNKKEISQLHTMAVTKK"
     gene            complement(37482..38051)
                     /gene="scpB"
                     /locus_tag="ACL29Z_000353"
     CDS             complement(37482..38051)
                     /gene="scpB"
                     /locus_tag="ACL29Z_000353"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000105309.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005515 - protein binding [Evidence IEA];
                     GO_process: GO:0007059 - chromosome segregation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SMC-Scp complex subunit ScpB"
                     /protein_id="HGR0068722.1"
                     /translation="MSTLAKIEALLFVAGEDGIRVRQLAELLSLPPTGIQQSLGKLAQ
                     KYEKDPDSSLALIETSGAYRLVTKPQFAEILKEYSKAPINQSLSRAALETLSIIAYKQ
                     PITRIEIDAIRGVNSSGALAKLQAFDLIKEDGKKEVLGRPNLYVTTDYFLDYMGINHL
                     EELPVIDELEIQAQESQLFGERIEEDENQ"
     gene            complement(38070..38798)
                     /locus_tag="ACL29Z_000354"
     CDS             complement(38070..38798)
                     /locus_tag="ACL29Z_000354"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000351912.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="segregation/condensation protein A"
                     /protein_id="HGR0068723.1"
                     /translation="MDIKLKDFEGPLDLLLHLVSKYQMDIYDVPITEVIEQYLAYVST
                     LQAMRLEVTGEYMVMASQLMLIKSRKLLPKVAEVTDLGNDLEQDLLSQIEEYRKFKLL
                     GEHLEAKHQERAQYYSKAPTELIYEDAELVHDKTTIDLFLAFSNILAKKKEEFAQNHT
                     TILRDEYKIEDMMIIVKESLVGRAQLRLQDLFKEAQNVQEVITLFLATLELIKTQELI
                     LVQEESFGDIYLMEKKEESQVPQS"
     gene            complement(38798..39532)
                     /gene="xerD"
                     /locus_tag="ACL29Z_000355"
     CDS             complement(38798..39532)
                     /gene="xerD"
                     /locus_tag="ACL29Z_000355"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001808689.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific tyrosine recombinase XerD"
                     /protein_id="HGR0068724.1"
                     /translation="MRDRISAFLEEKQGLSVNSKQSYKYDLEQFLDMVGERISETSLK
                     IYQAQLANLKISAQKRKISACNQFLYFLYQKGEVDSFYRLELAKQAEKKTEKPEILYL
                     DSFWQESDHPEGRLLALLILEMGLLPSEILAIKVADINLDFQVLRISKASQQRIVTIP
                     TALLSELEPLMGQTYLFERGEKPYSRQWAFRQLESFVKEKGFPSLSAQVLREQFILRQ
                     IENKVDLYEIAKKLGLKTVLTLEKYR"
     gene            complement(39529..39990)
                     /gene="cbpB"
                     /locus_tag="ACL29Z_000356"
     CDS             complement(39529..39990)
                     /gene="cbpB"
                     /locus_tag="ACL29Z_000356"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000560721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0180001 - cyclic-di-AMP binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cyclic-di-AMP-binding protein CbpB"
                     /protein_id="HGR0068725.1"
                     /translation="MIAKEFETFLLGQEETFLTPAKNLAVLIDTHNADHATLLLSQMT
                     YTRVPVVTDEKQFVGTIGLRDIMAYQMEHDLSQEIMADTDIVHMTKTDVAVVSPDFTI
                     TEVLHKLVDESFLPVVDAEGIFQGIITRKSILKAVNALLHDFSKEYEIRCQ"
     gene            complement(39987..40508)
                     /locus_tag="ACL29Z_000357"
     CDS             complement(39987..40508)
                     /locus_tag="ACL29Z_000357"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001118598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HGR0068726.1"
                     /translation="MAKQTIIVMSDSHGDSLIVEEVRDRYVGKVDAVFHNGDSELRPY
                     SPLWEGIRVVKGNMDFYAGYPERLVTELGSTKIIQTHGHLFDINFNFQKLDYWAQEEE
                     AAICLYGHLHVPSAWMEGKILFLNPGSISQPRGTIRECLYARVEIDDSYFKVDFLTRD
                     HEVYPGLSKEFSR"
     gene            complement(40484..41455)
                     /locus_tag="ACL29Z_000358"
     CDS             complement(40484..41455)
                     /locus_tag="ACL29Z_000358"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000182414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0047429 - nucleoside triphosphate
                     diphosphatase activity [Evidence IEA];
                     GO_process: GO:0009143 - nucleoside triphosphate catabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside-triphosphate diphosphatase"
                     /protein_id="HGR0068727.1"
                     /translation="MTNKIYEYKDDQDWYVGSYSIFGGVNSLSDYKTDFPLFEFSKIF
                     GDEEYGFPLSVTVLRYGSTYRLFSFVVDMLNQEMGRNLEVIQRHGALLLVENGQLLYV
                     ELPKEGVNVHDFFETSKVRETLLIATRNEGKTKEFRAIFDKLGYDVENLNDYPDLPEV
                     AETGMTFEENARLKAETISQLTGKMVLADDSGLKVDVLGGLPGVWSARFAGVGATDRE
                     NNAKLLHELAMVFELKDRSAQFHTTLVVASPNKESLVVEADWSGYINFEPKGENGFGY
                     DPLFLVGETGESSAELTLEEKNSQSHRALAVKKLLEVFPSWQSKLSL"
     gene            complement(41452..42246)
                     /gene="racE"
                     /locus_tag="ACL29Z_000359"
     CDS             complement(41452..42246)
                     /gene="racE"
                     /locus_tag="ACL29Z_000359"
                     /EC_number="5.1.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000370386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008881 - glutamate racemase activity
                     [Evidence IEA];
                     GO_process: GO:0008152 - metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate racemase"
                     /protein_id="HGR0068728.1"
                     /translation="MDNRPIGFLDSGVGGLTVVRELMRQLPHEEIVYIGDSARAPYGP
                     RPAEQIREYTWQLVNFLLTKDVKMIVIACNTATAVVWEEIKAQLDIPVLGVILPGASA
                     AIKSSQGGKIGVIGTPMTVQSDIYRQKIHDLDPDLQVESLACPKFAPLVESGALSTSV
                     TKKVVYETLRPLVGKVDSLILGCTHYPLLRPIIQNVMGPKVQLIDSGAECVRDISVLL
                     NYFEINRGRDAGPLHHRFYTTASSQSFAQIGEEWLEKEIHVEHVEL"
     gene            complement(42453..42701)
                     /locus_tag="ACL29Z_000360"
     CDS             complement(42453..42701)
                     /locus_tag="ACL29Z_000360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000364981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YneF family protein"
                     /protein_id="HGR0068729.1"
                     /translation="MDLLLAIVLIVLAFLGGALGGMYLVRKQIEKEFADNPRLNAEAV
                     RTLLSANGQKPSEAKVQQVYHQIIRQQKAALANNKKKK"
     gene            complement(42957..44582)
                     /gene="treC"
                     /locus_tag="ACL29Z_000361"
     CDS             complement(42957..44582)
                     /gene="treC"
                     /locus_tag="ACL29Z_000361"
                     /EC_number="3.2.1.93"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000171230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0008788 - alpha,alpha-phosphotrehalase
                     activity [Evidence IEA];
                     GO_process: GO:0005991 - trehalose metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alpha,alpha-phosphotrehalase"
                     /protein_id="HGR0068730.1"
                     /translation="MTLDKGKVVYQIYPKSYKDTTENGIGDFRGIIEKIPYLAKLGVD
                     MVWLNPFYPSPQRDNGYDISDYMAVDPLFGDMADFEEMVCVGKEHKIDFMLDMVLNHC
                     STEHEWFQKALAGDKYYQDFFFIQDQPTDWQSKFGGSAWAPFGDTGKYYLHLFDETQA
                     DLNWRNPNVRKELFKVVNFWRDKGVKGFRFDVINLIGKDEVSVDCPENEGKPAYTDKP
                     IVHNYLRMMNQATFGSDDSFMTVGEMSSTTMENCVLYSSPDRQELSMTFNFHHLKVDY
                     KDGQKWTLAPFDFEELKSLYHSWGKEMSDKDGWSALFWNNHDQPRALNRFVDIQNFRK
                     EGATMLAASIHLSRGTPYIYMGEEIGMIDPDYDSMADYVDVESLNAYQMLLEEGKSQQ
                     EAFQIIQAKSRDNSRIPMQWDASENAGFSTGTPWLKAGKSYKDINVENEIQGPIFTFY
                     QDLIRLRKEMPIISEGSYKPAFEDSKQVYAFERQFEDQKLLVLNNFYAKEVEIDLPAV
                     YQNGQILISNYEDAEVSEKILLKPYQTLAIYVN"
     gene            complement(44760..46727)
                     /gene="treP"
                     /locus_tag="ACL29Z_000362"
     CDS             complement(44760..46727)
                     /gene="treP"
                     /locus_tag="ACL29Z_000362"
                     /EC_number="2.7.1.201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_function: GO:0015574 - trehalose transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0015771 - trehalose transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system trehalose-specific EIIBC component"
                     /protein_id="HGR0068731.1"
                     /translation="MGKFEQEAKDLLQAIGGKENVTAVTHCATRMRFVLRDDKKANVK
                     AIESIPAVKGTFTNAGQFQVIIGNDVPIFYNDFTAVSGIEGVSKEATKSAAKSNQNVV
                     QGVMTTLAEIFTPIIPALIVGGLILGFRNVLEGVHWSMLDGKTITESSQFWAGVNHFL
                     WLPGEAIFQFLPVGITWSVSRKMGTSQILGIVLGICLVSPQLLNAYAVASTPAADIAA
                     NWVWNFGYFTVNRIGYQAQVIPALLAGLSLSYLEIFWRKHIPEVISMIFVPFLSLIPA
                     LILAHTVLGPIGWTIGQGLSSVVLAGLTGPVKWLFGAIFGALYAPFVITGLHHMTNAI
                     DTQLIADAGGTALWPMIALSNIAQGSAVFAYYFMHRHDEREAQVSLPATISAYLGVTE
                     PALFGVNVKYIYPFVAGMTGSALAGMLSVTFNVTAASIGIGGLPGILSIQPQYMLPFA
                     GTMLVAIVVPMLLTFFFRKAGLFTKIEGDTNLQAEFVAQEEAEFVSHEPVELTSVEII
                     SPLTGQVKELSQATDPVFASGVMGQGLVIEPSQGELTSPVNGTVTVLFPTKHAIGIVS
                     DEGVELLIHIGMDTVGLDGKGFESLVVQGDHVIVGQQLIRFDMDVIKAAGLVTETPVI
                     ITNQDAYTATITGTYPTTIQAGASLMVATRI"
     gene            46912..47622
                     /gene="treR"
                     /locus_tag="ACL29Z_000363"
     CDS             46912..47622
                     /gene="treR"
                     /locus_tag="ACL29Z_000363"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001865045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="trehalose operon repressor"
                     /protein_id="HGR0068732.1"
                     /translation="MKKYQQLFKQIQETIQNETYAVGDFLPSEHDLMEQYQVSRDTVR
                     KALSLLQEEGLIKKIRGQGSQVVKEETVNFPVSNLTSYQELVKELGLRSKTNVVSLDK
                     IIIDKKSSLITGFPEFRMVWKVVRQRVVDDLVSVLDTDYLDMELIPNLTRQIAEQSIY
                     SYIENGLKLLIDYAQKEITIDHSSDRDKILMDIGKDPYVVSIKSKVYLQDGRQFQFTE
                     SRHKLEKFRFVDFAKRKK"
     gene            complement(47655..48458)
                     /locus_tag="ACL29Z_000364"
     CDS             complement(47655..48458)
                     /locus_tag="ACL29Z_000364"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000157668.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGR0068733.1"
                     /translation="MASLLTLENIHKTFEAGTVNENHVLKGLDLEVEEGDFISVICGN
                     GAGKSTLMNILAGNLSVDEGDLLLAGKSIKHLNVRKRANDIARVFQDPKMGTASRLTI
                     EENMAIALRCEQKRGLGWGVKEKDRIQFQEALKELNIGLENRLKVDTQYLSGGQRQAL
                     TLVMAALVKPKLLLLDEHTAALDLKTSQMVMNLTQKIVEHHQWTTLMITHDMNHAIEY
                     GNRLIMLYQGKIVVDVKGEEKKHLTVEDLMHLFQKNSGQSLVSDELVLG"
     gene            complement(48471..49348)
                     /locus_tag="ACL29Z_000365"
                     /pseudo
     CDS             complement(48471..49348)
                     /locus_tag="ACL29Z_000365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001012086.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
     gene            complement(49360..50297)
                     /locus_tag="ACL29Z_000366"
                     /pseudo
     CDS             complement(49360..50297)
                     /locus_tag="ACL29Z_000366"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000512061.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate binding protein"
     gene            complement(50788..51714)
                     /locus_tag="ACL29Z_000367"
     CDS             complement(50788..51714)
                     /locus_tag="ACL29Z_000367"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001291287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HGR0068734.1"
                     /translation="MSEKLVEIKDLEISFGEGSKKFVAVKNANFFINKGETFSLVGES
                     GSGKTTIGRAIIGLNDTSNGDIIFDGQKINGKKSREQAAELIRRIQMIFQDPAASLNE
                     RATVDYIISEGLYNHRLFKDEEERKEKVQNIIREVGLLAEHLTRYPHEFSGGQRQRIG
                     IARALVMQPDFVIADEPISALDVSVRAQVLNLLKKFQKELGLTYLFIAHDLSVVRFIS
                     DRIAVIYKGVIVEVAETEELFNNPIHPYTQALLSAVPIPDPILERKKVLKVYDPSQHD
                     YETDKPSMVEIRPGHYVWANQAELARYQKGLN"
     gene            complement(51725..52792)
                     /locus_tag="ACL29Z_000368"
     CDS             complement(51725..52792)
                     /locus_tag="ACL29Z_000368"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866499.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGR0068735.1"
                     /translation="MTKEKNVILTARDIVVEFDVRDKVLTAIRGVSLELVEGEVLALV
                     GESGSGKSVLTKTFTGMLEENGRIAQGSIDYRGQDLTALSSHKDWEQIRGAKIATIFQ
                     DPMTSLDPIKTIGSQITEVIVKHQGKTAKEAKELAIDYMNKVGIPDADRRFNEYPFQY
                     SGGMRQRIVIAIALACRPDVLICDEPTTALDVTIQAQIIDLLKSLQNEYHFTTIFITH
                     DLGVVASIADKVAVMYAGEIVEYGTVEEVFYDPRHPYTWSLLSSLPQLADDKGDLYSI
                     PGTPPSLYTDLKGDAFALRSDYAMQIDFEQKAPQFSVSETHWAKTWLLHEDAPKVEKP
                     AVIANLHDKIREKMGFAHLAD"
     gene            complement(52801..53727)
                     /gene="oppC"
                     /locus_tag="ACL29Z_000369"
     CDS             complement(52801..53727)
                     /gene="oppC"
                     /locus_tag="ACL29Z_000369"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="oligopeptide ABC transporter permease OppC"
                     /protein_id="HGR0068736.1"
                     /translation="MSTIDKEKFQFVKRDDFASETIDAPAYSYWKSVFKQFMKKKSTV
                     VMLGILVAIILISFIYPMFSKFDFNDVSKVNDFSVRYIKPNAEHWFGTDSNGKSLFDG
                     VWFGARNSILISVIATVINLVIGVFVGGIWGISKSVDRVMMEVYNVISNIPPLLIVIV
                     LTYSIGAGFWNLIFAMSVTTWIGIAFMIRVQILRYRDLEYNLASRTLGTPTLKIVAKN
                     IMPQLVSVIVTTMTQMLPSFISYEAFLSFFGLGLPITVPSLGRLISDYSQNVTTNAYL
                     FWIPLTTLVLVSLSLFVVGQNLADASDPRTHR"
     gene            complement(53727..55223)
                     /locus_tag="ACL29Z_000370"
     CDS             complement(53727..55223)
                     /locus_tag="ACL29Z_000370"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000759888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HGR0068737.1"
                     /translation="MKKYIFMRVLRSLVSIFLVTTLTYTIIYTLVPRKLIFKQDPNYN
                     KIATTADKRDNYENTVFERMGYIEYYDTKELQEKASSMDSSVTVEANATNKAIYEKYI
                     NQLGHGWTLGEFTESGQFYATREIPIFERVFHFYANLIDIDHTNKIQDPENPDLKRYL
                     RFENDPAIGWSLVGSGTKHKYLLYFNSQFPFVHQNFVNLNLGDSYPTYANTPVLQVIT
                     QGQGQTKTAQVQFPTGKKTSSVNIYSRTYKSPSQADSREVASYGKDDPYTATESNYQY
                     PSMIVSSAITGLIGLVLAYALAVPLGSAMARFKNTWIDSLSTGTLTFLLALPTIALVY
                     IVRLIGSSIALPDSFPILGAGDWRSYVLPAVILGLLGAPVTAIWIRRYMIDLQSQDFV
                     RFARAKGLSEKEISNKHIFKNAMVPLVSGIPGAIIGVIGGATLTETVFAFPGMGKMLI
                     DSVKASNNSMVVGLVFIFTCISIFSRLLGDIWMTIIDPRIKLTEKGGK"
     gene            complement(55290..57269)
                     /locus_tag="ACL29Z_000371"
     CDS             complement(55290..57269)
                     /locus_tag="ACL29Z_000371"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000742236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptide ABC transporter substrate-binding
                     protein"
                     /protein_id="HGR0068738.1"
                     /translation="MKKNRVFATAGLVLLAAGVLAACSSSKSSDSSAPKAYGYVYTAD
                     PETLDYLISSKNSTTVVTSNGIDGLFTNDNYGNLAPAVAEDWEVSKDGLTYTYKIRKG
                     VKWFTSDGEEYAEVTAKDFVNGLKHAADKKSEAMYLAENSVKGLADYLSGTSTDFSTV
                     GVKAVDDYTLQYTLNQPEPFWNSKLTYSIFWPLNEEFETSKGSDFAKPTDPTSLLYNG
                     PFLLKGLTAKSSVEFVKNEQYWDKENVHLDTINLAYYDGSDQESLERNFTSGAYSYAR
                     LYPTSSNYSKVAEEYKDNIYYTQSGSGIAGLGVNIDRQSYNYTSKTTDSEKVATKKAL
                     LNKDFRQALNFALDRSAYSAQINGKDGAALAVRNLFVKPDFVSAGEKTFGDLVAAQLP
                     AYGDEWKGVNLADGQDGLFNADKAKAEFAKAKKALEADGVQFPIHLDVPVDQASKNYI
                     SRIQSFKQSVETVLGVENVVVDIQQMTSDEFLNITYYAANASSEDWDVSGGVSWGPDY
                     QDPSTYLDILKTTSSETTKTYLGFDNPNSPSVVQVGLKEYDKLVDEAAKETSDLNVRY
                     EKYAAAQAWLTDSSLFIPAMASSGAAPVLSRIVPFTGASAQTGSKGSDVYFKYLKLQD
                     KVVTKEEYEKAREKWLKEKAESNEKAQKELASHVK"
     gene            complement(57955..59148)
                     /locus_tag="ACL29Z_000372"
     CDS             complement(57955..59148)
                     /locus_tag="ACL29Z_000372"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008293041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008754 - O antigen ligase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="O-antigen ligase family protein"
                     /protein_id="HGR0068739.1"
                     /translation="MKSIGFIEKLKGLSSKELILLGIILSIFLPFYLFVVVLCLYIIS
                     LIFTGDMKSILQKMGEHPMLLLFLSYSTVISILAQNWMGLVASVGMFLFTIFFLHYQS
                     ILSHKFFRLILQFVLFGSVLSAAFASLEHFQIVKKFNYAFLSPNMQVWHQNRAEVTFF
                     NPNYYGIICCFCIMIAFYLFTTTKLNWLKVFCVIAGFVNLFGLNFTQNRTAFPAIIAG
                     AIIYLFTTIKNWKAFWLSIGVFAIGLSFLFSSDLGVRMGTLDSSMEERISIWDAGMAL
                     FKQNPFWGEGPLTYMHSYPRIHAPYHEHAHSLYIDTILSYGIVGTILLVLSSVAPVRL
                     MMDMSQESGKRPIIGLYLSFLTVVAVHGIFDLALFWIQSGFIFLLVMCSIPLEHRMLV
                     SDMTD"
     gene            complement(59286..60728)
                     /gene="gtfA"
                     /locus_tag="ACL29Z_000373"
     CDS             complement(59286..60728)
                     /gene="gtfA"
                     /locus_tag="ACL29Z_000373"
                     /EC_number="2.4.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001122330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004645 - 1,4-alpha-oligoglucan
                     phosphorylase activity [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sucrose phosphorylase"
                     /protein_id="HGR0068740.1"
                     /translation="MPIQNKTMLITYSDSLGNNLKDLYDNLEEHFGDAIGGVHLLPFF
                     PSTGDRGFAPVDYDEVDSAFGDWEDVKRLGERYYLMFDFMINHISRQSKYYKDYQEKH
                     EASEFKDLFLNWDKFWPENRPTQSDVDLIYKRKDRAPKQEIVFEDGSVEHLWNTFGEE
                     QIDLDVTKEVTMEFIRKTIQHLASNGCDLIRLDAFAYAVKKLDTNDFFVEPDIWDLLD
                     KVRDIAAEYGTELLPEIHEHYSIQFKIADHDYYVYDFTLPMVTLYTLYSSRTERLAKW
                     LKMSPMKQFTTLDTHDGIGVVDVKDILTDEEIDYASNELYKVGANVKRKYSSAEYNNL
                     DIYQINSTYYSALGDDDVKYFLARLIQAFAPGIPQVYYVGLLAGKNDLKLLEETKEGR
                     NINRHYYSNEEIAKEVQRPVVKALLNLFSFRNRSEAFDLEGTTEIETPTAHSIVIKRQ
                     NKDKSVTAVVEIDLQNQTYRVIENGVEVSF"
     gene            complement(61039..61872)
                     /locus_tag="ACL29Z_000374"
     CDS             complement(61039..61872)
                     /locus_tag="ACL29Z_000374"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000711263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HGR0068741.1"
                     /translation="MKQDERKALIGKYILLILGSVLILVPLLATLFSSFKPTKDIVDN
                     LFGFPTNFTWDNFSRLLADGIGGYYWNSVVITVLSLLAVMIFIPMAAYSIARNMSKRK
                     AFTIMYTLLILGIFVPFQVIMIPITVMMSKLGLANTFGLILLYLTYAIPQTLFLYVGY
                     IKISIPESLDEAAEIDGANQFTTYFRIIFPMMKPMHATTMIINALWFWNDFMLPLLVL
                     NRDSKMWTLPLFQYNYAGQYFNDYGPSFASYVVGIISITIVYLFFQCHIISGMSNGAV
                     K"
     gene            complement(61886..62752)
                     /locus_tag="ACL29Z_000375"
     CDS             complement(61886..62752)
                     /locus_tag="ACL29Z_000375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000757171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HGR0068742.1"
                     /translation="MKKVLQKYWAWAFVVIPLLLQAIFFYVPMFQGAFYSFTNWTGLT
                     YNYKFVGLNNFKLLFMDPKFMNAIGFTAIITIAMVVGEIALGIFIARVLNSKIKGQTF
                     FRAWFFFPAVLSGLTVALIFKQVFNYGLPAIGNALHIEFLQTSLLGTKWGAIFAAVFV
                     LLWQGVAMPIIIFLAGLQSIPTEITEAARIDGATSKQVFWNIELPYLLPSVSMVFILA
                     LKGGLTAFDQVFAMTGGGPNNATTSLGLLVYNYAFKNNQFGYANAIAVILFFLIVVIS
                     IIQLRVSKKFEI"
     gene            complement(62766..64025)
                     /locus_tag="ACL29Z_000376"
     CDS             complement(62766..64025)
                     /locus_tag="ACL29Z_000376"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HGR0068743.1"
                     /translation="MEWYKKIGLLATTGLALVGLGACSNYGKSADGTVTIEYFNQKKE
                     MTKTLEEITRDFEKENPKIKVKVVNVPNAGEVLKTRVLAGDVPDVVNIYPQSIELQEW
                     AKAGVFEDLSNKDYLKRVKNGYAEKYAVNEKVYNVPFTANAYGIYYNKDKFEELGLKV
                     PETWDEFEQLVKDIVAKGQTPFGIAGADAWTLNGYNQLAFATATGGGKEANQYLRYSQ
                     PNAIKLSDPIMKDDIKVMDILRINGSKQKNWEGAGYIDVIGAFARGDVLMTPNGSWAI
                     TAINEQKPNFKIGTFMIPGKEKGQSLTVGAGDLAWSISATTKHPKEANAFVEYMTRPE
                     VMQKYYDVDGSPTAIEGVKQAGEDSPLAGMTEYAFTDRHLVWLQQYWTSEADFHTLTM
                     NYVLTGDKQGMVNDLNAFFNPMKADVD"
     gene            complement(64060..66222)
                     /locus_tag="ACL29Z_000377"
     CDS             complement(64060..66222)
                     /locus_tag="ACL29Z_000377"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000538915.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-galactosidase"
                     /protein_id="HGR0068744.1"
                     /translation="MGVRIENNLFYVESKNLSLIIENRNGYLLLKHLGKTIKNYKGSN
                     SVYERDHAFSGNPTATNRTFSLDTQRQIFGQHGLGDFRKPTIQVQHSVTEVTDFRFVE
                     AKILKGQNGPQGLPSPHSMDDTETLVLMLEDSKAQLSLTLYYTTFNNDATIASYSKLD
                     NNSNQEVVIHKDFSFMADFPAADYEIVTLQGAYAREKTVRRQQVEQGIFSISSNRGAS
                     GHAQTPALLLCEQGVTEDAGNVFAIQLMYSGNFEAFVQKNQLNEVRVAIGINPENFSC
                     KLAPEEYFETPVALVTHSDQGLTGISHESQNFVLKHIMLSEFSKKERPILINNWEATY
                     FDFQIEKLLELADEAKKVGIELFVLDDGWFGNRFDDNRALGDWVVNEEKLGGSLESLI
                     SAIHERGLQFGLWLEPEMISVDSDLYRRHPDWAIQVPDYEHTYSRNQLVLNLANPQVV
                     EYLKSVLDQLLSYHDIDYIKWDMNRNITKLGNGLTYLETQMQSHQYMLGLYELVSYLT
                     EKHSHILFESCSGGGGRNDLGMMRYFPQVWASDNTDAIARLPIQYGSSYLYPTISMGA
                     HVSAVPNHQMGRMTPLETRGLVAMMGNLGYELDLTNLSDEEKATIANQVNLYKELRPV
                     VQLGQQYRLINPDTVSNEAAVQFNYENQTIVTYVRVLSVVETMETTLKLKDLDEEGLY
                     KLQENGEIYSGAELMYAGLTVILSQGDFLSRQYIFRRL"
     gene            66330..67190
                     /locus_tag="ACL29Z_000378"
     CDS             66330..67190
                     /locus_tag="ACL29Z_000378"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000959966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HGR0068745.1"
                     /translation="MLVFSEYQTGTIDLALSFYGYEECTPNYSFGPAIRDTYVLHYIT
                     KGQGKFHYKGKIVDLKEGDFFLLKPEELTFYQADSKEPWAYYWLGITGGKSPDYFALS
                     QISDQSYLIQSETCHTQTTAKLISDIVRFAQITKSSELSQLHIMGQLHELMFHLGTIA
                     PNQKKKNISSTHQLYLECKRLIDSHYPQSLTIQDLAKELSVHRSYLSSVFKEFNTLSP
                     KEYLLYIRMHRARQLLENTQESIKVIAYSVGFSDPLHFSKAYKQYFNQTPSHTRKEYS
                     QYQLVRKATL"
     gene            67187..68122
                     /gene="birA"
                     /locus_tag="ACL29Z_000379"
     CDS             67187..68122
                     /gene="birA"
                     /locus_tag="ACL29Z_000379"
                     /EC_number="6.3.4.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000844514.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional biotin--[acetyl-CoA-carboxylase]
                     ligase/biotin operon repressor BirA"
                     /protein_id="HGR0068746.1"
                     /translation="MKSYQAVYQILSKETDYISGEKIAEKLSLSRTSIWKAIKRLEQE
                     GIEIDSIKNRGYKLMNGDLILPEILEENLPIKVSFKPETKSTQLDAKEAIDLGHEANT
                     LYLASYQTAGRGRFQRSFYSPQGGIYMTLHLKPNLPYDKLPSYTLLVAGAVYKAIKNL
                     TLIDVDIKWVNDIYLNNHKIGGILTEAMTSVETGLVTDIIIGVGINFTIKDFPQELKE
                     KAASLFKATAPITRNELIIEIWRAFFETPAEELLYLYKKQSFILGKEVTFTLEQKDYK
                     GLAKDISENGKLLIQCDNGKEIWLNSGEISLNSWK"
     gene            complement(68248..68335)
                     /locus_tag="ACL29Z_000380"
     tRNA            complement(68248..68335)
                     /locus_tag="ACL29Z_000380"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(68299..68301),aa:Ser,seq:gct)
     gene            complement(68342..68415)
                     /locus_tag="ACL29Z_000381"
     tRNA            complement(68342..68415)
                     /locus_tag="ACL29Z_000381"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(68379..68381),aa:Ile,seq:gat)
BASE COUNT        20555 a        15281 c        12496 g        20084 t
ORIGIN      
        1 acttcttctg tcttattatc ttgtttattg tcgatcttgt cattcatttg tctattatct
       61 ttacttgagt taaactctcc gttcttctgg ttactatcaa ttacattatt tgaattagat
      121 tgtttttcct ctttgttttt ttctttttcg tttttatcac ttaaattatt tgttacaatt
      181 ttgtaaagcc cattctccgt tacaatattg aaattaccat cgctatcacg tataacaggt
      241 tctttcccat ttgcattaga tttgatgaat gatatatact taccggataa attataaaat
      301 tggttattta aaacggttat tttacccttt gaatcctcaa taacaattcc ttctttacca
      361 ccgaatatac tattctctga gactactaaa ttatcactaa ctcgtaataa ttcaatattt
      421 ggttgttctg tttccttaga attattatta attacatttt ttgttacagt aatatctgat
      481 acttttccta aatattctgc actatctttt gcaactcgta tcgcttttgt tttaggatcg
      541 gcaatattaa atatattttc ggcgataacc atctgtttat ttaaatctaa taggtcttta
      601 gtgtttttat agctataagc atttactaaa gctgctccgt tttctcgata atgtacactc
      661 tctcctttaa ctttcttatc aaagcgattt cctttgatta atacatcagt gaatcctgta
      721 aaacgtacac ctgaatacat catgttatca aaatgattat ttaaaatttt aatattagag
      781 gggttctgtg tcgacaatgt ttgatagtgt gtgccaattg ctgttactaa ttccccagat
      841 ttatcacttt tgccaaaata ggaattttga atagtcacat tttcagattt tttcccatca
      901 tcattcaagg cataaggaaa accttttcta gttaatggtt caatctgaat gctctcctta
      961 cttatgattt gcccatcctt catcgttttg ggtaaggctt gcccaagaaa acgagaatta
     1021 tcaactaata catttttcga acctgcaatt tgaatagcat gcccttgata actatccttg
     1081 aatgttacat tttttatagt tacgttattt gaattcccaa tagcaaatgc acctgaagaa
     1141 tttataagtg gtagattttt tgctttagtt ccttcttcat tcaaagcacc gttcatatca
     1201 atcgtaccac cagaataact aatatcttct gttgggcccc attctacttg cgcaccatca
     1261 tccgtaaata aacctgtcat aaaaacaatg gaagggtgat tcttaatatt tataccattt
     1321 agaattgtag ctttctcatt caattctaag tgtgtatgac tttttaaaaa aacaatttct
     1381 tttactaaat aagttccttc aggaaaatat acatttcctc cacctagccc ttgagctgca
     1441 gcatctattg catcttgaat tgcttgtcga tcatcatgaa tcccatcacc taccgcacca
     1501 taatctttta cacttaaagc agtatcttca aattcttttt tgataattct gtcacttata
     1561 acatcttcct tataactctt attttcatta gtagatgtta ctgtagattc aactgttctg
     1621 ttgtctaatt gtgaattgga acgaatagta ccattagagc tgatactatt aacacttaac
     1681 gaattatcta aaccattagt ggttgaatta gaggcaatca tttcagcaga acgattctga
     1741 ttaacagttg gtgaattatc taaatcatta gtaattgcat tagaagactc ttttgtagcc
     1801 atcggtgaag aactagtaac aacttcatcc gataaaatac cttggcttcc caaaattgaa
     1861 attgccaata gtaccgagca agtccccacc tttaatttac gaatactgaa tacctcatta
     1921 ggaacaaaat atttcatcag aacctccaat ttttttacta tttttaacaa ttgattatta
     1981 cttttcttaa aatagataga atgacaccgc tgtcattatc tttatcatat attttccaaa
     2041 ttgaattgtc aaggaataac acaagaaaat attaaaattt atactcttcg gaaatctctt
     2101 caaactaggt cagtgccgcc ttgacctaag tctaggttac tgacttggtc agttctatag
     2161 tagactgaaa ctaaaatagt acacctctac ttctaaaaca ttgttagaaa tcgatttgac
     2221 tgtcccgatc aatttgtcct attcttattt cattttacta tatctacaac ctcaaagcag
     2281 ggttttgagc tatctatggc caacttccta gtttgctctt tagccttcca ttcaaaagtg
     2341 atgctatctt tcttagcttg aatataaaat atcccattta ctatatttaa atttgttgat
     2401 atgttgtaaa ttataaatga aagaacaaat atcttgtcat acaagcattc gccagggata
     2461 tttacatgaa tatcgctcat atggcggatt gaaactaaaa cactacaata tatttcttaa
     2521 atagaccttc tataaaagct agatttaacc tcgataaaaa tagatgcagt gcttctaaaa
     2581 tactggaata gggcatatag gtaatcgtag acaagtgttt tatagattgt ctcgcgggag
     2641 atctaatgat gtatagcaag catcactaaa catatagaat atttgtatta ttataatatc
     2701 aatatgctat aaattctatc atgcaaaaga atgactagaa catgaaagac aggcacaaaa
     2761 ctttgaacaa tattctgaaa acaaaaaaag acgcgagttt ccacaatctc actcatggaa
     2821 actcacgtct ttcaaaaaat agggtgaatt gaaaactaga acaagacact agattttcta
     2881 aatgatgtct agtaaggatt ctaaatgcta caccaaattg ctcacatctt atttcaaacc
     2941 acgggactcc cacaagaaag gaaaatccta taaaaattct ctctctgagg agaaaggagc
     3001 ctcaactaca ggtgtaaact attatcaatt gaaaacaaca gtttttacac tcaattagac
     3061 tttttaagga caggatcact ttcgcttgac tgtagtttgt catttttttg ataaagttag
     3121 cactttttca gaaactgttt tgaaagtctc aatgatatag tctacttctt catcgcttaa
     3181 tttagtatga agagggaggg taatttcatt ctcaaagaag gcataggcct taggatagtt
     3241 cgtcatatca aatccaagat tcttataggc tgtcaagaga ggaagcggtt tgtagtgaac
     3301 attacttgca attcctgctt tagccaattc ttggatgatg aggttgcgtt cttctaggct
     3361 tgctccttct acacgggtga tgtagaggtg gcgtgaagat tcgacagttt cagtcttgtg
     3421 tgccaaagga tggatgcgag aacctgcaaa accactatca tagcggtcca caatgtcctt
     3481 acggcgttgc aacaaacttg gatagcggtc caattgtacc aaaccaagtg aagccatgat
     3541 atcggtcatg ttgcacttat aggctggtgt aacgatatcg tattcccatg accccagttg
     3601 catcttggca agagcatcct tagtttgccc gtgaagggaa aggatttgga attccttgta
     3661 catctcttcg tcatcaatca ctggattggc tttccaagtc gcacttccac cttctgccgt
     3721 tgtaaagttc ttaacggcat ggaatgagaa ggaagtaaaa tcagcgatag aaccagaagg
     3781 ttgtccttta taagtagatc ccaaagcgtg ggcactatca gagacaatga caatacggtt
     3841 aaaggccttt tgccacttgc ttgaagcggt aaagaagtca cgttttttct ccacgacttg
     3901 gaacaaacgg tcataatcgc aaacaatccc tgcgagctct actgggataa tcaccttagt
     3961 tttctcagtg atagcttgct caagcaggtc atagtccatc tcaaacgtat ctgcttggat
     4021 atccaccatg acaggggttg ctcccacgtg cgtaatgaca ctacatgaag ccgtataggt
     4081 catggctgga acgatgactt catcaccagg tcccacttcc aaaacgcgta aaatcaactc
     4141 cagagcggct gtcgcagagt tgagacaaac agtcttaggt gtctgtgtgt aaagagacaa
     4201 gcggcgctcc agttcttttg ttttaggacc tgttgtgatc caaccagaac gcagggtatc
     4261 cgctacttca gcaatttctg cttctgtgat atcaggcggt gaaaatggaa tattgtaatt
     4321 tggcattgat ttgctccttt tatctgtact cattttctta tgactacttt attttagtac
     4381 ctcaaacacg gtttgaaaca tgattttgat gtccccaaag aaactaaact ctcggagata
     4441 ggcgaggtta tagcgcatct tttcaggaag aacatgctcc acataggcct gatcaactga
     4501 cagacctttc tccgtcattt gactgatgat ggtgtcctca tccttgtagt tgatgctggc
     4561 tggagaggta attcctgctt gcaagagcaa ggttgccatc atttcagggc tatactgctc
     4621 tgtataacgt ggcacttcag gtcgtgtacc gacaaaggac atctcacctt taaggacatt
     4681 gaccaactga ggcagttcgt ccaaacggac acgtcggatg aaatttccaa ccttggtaat
     4741 acggctatcg ttagcagaag tcaccagact tcctttttta tccgcatccg tcaccatggt
     4801 acggaacttc caaatcttga accgacggtt gtactgggtc acacgctctt gcttgtaaat
     4861 cactggcccc ttgctatcca acttgatcca aatgctcaag atgagaaaga tgggagaagt
     4921 tagaaccagt aagaccaagg ccaaaaccca gtccaagcaa cgcttgaaaa tcagcgaacc
     4981 cttcctttta gagacaagct ggtagtaaga ctcaacctcg cttgatttca tttccacagg
     5041 caagtcttcc catttcagca tgctgttctc ctttgttttt attatactat ttgtcaacat
     5101 ttttcattat accacaaaat ggaaaaggcg gtgaaagaaa tctgtaattt gaaggatttc
     5161 cttctagtac tcaatgaaaa tcaaagtaca gctttgagat tgcagataaa gctgacatgg
     5221 tttaaagaga ttttcaaaga gtataggcca tggcccctgc ctgcaaacta tacatcttgt
     5281 gataggttcc tcccagagtc aagagttcct catgggttcc actctcgata atgcgtccct
     5341 tatccaagac atagatgcag ttggcgtctt gaatagtaga aaggcggtga gcgatagcaa
     5401 tagttgttcg gccctgtctc atcttcgcca gagaagcttg aaccaagctt tctgtttcag
     5461 agtcaatatt ggctgtcgct tcatccaaaa tcaggatttt aggctggctg gcgactgttc
     5521 tagcaaaggc aagaagctgg cgctgcccag tagagaagct cgaaccacgc tcggaaacag
     5581 gggagtcgta cccctgagga agttcttgaa taaaggaatc tgcatccaca aaggctgccg
     5641 cagcctgaac ctgctcatca ctgatttctt ggtacatggc gatattggac ttaatagttc
     5701 catgatagag gaagggttcc tgtaagacca aaccgatgtt ttttctcagc tcttcttgac
     5761 tgaaatccct gatatccaca tcatccaaga gaactctccc tgactggaat tcataaaagc
     5821 gcatgaggac attgataata gacgatttcc ctgaacctgt atgacctaca aaggcaatgg
     5881 tttcaccctt attaacagag aaagaaatgt catccagaat cggatgttta ccgtcatacg
     5941 agaaacacac atgttcaaaa cggatattgc cttctttgac tttggcttgc ccattttctt
     6001 gaaggggctc ataggtcctc tcatcgatta aggcaaagac acggcctgca gaaaccatag
     6061 acgtttgcag tgttgaaaag ttttgcgtca cctcaatcaa agggtcaaag aggcggttga
     6121 tgtactggat aaaagcatac atggtcccgg ccgttatccc gatagaaaga ccacgatagc
     6181 caaaataggt catcaagaca gcataaccta gaagtttcaa caaactcatg gcaggtctca
     6241 aaaagagggc atccaaggct acagaacggt tggcataggc caagtgctct tggttgattt
     6301 catcaaattc tgcctgcagg cgcttctctt gattaaaagc ctgaataatc ctgattccct
     6361 cgatattctc tgccagctta ctattgatat ctgacaagag acttctggtt ttctcgatga
     6421 ttttcactga cttttttcga tagagattga ccaaaaggaa aatcaagggg agaaagagca
     6481 agactaatgc tgtcaaacga aaatccagca ccaacatggt ataaagggtt gtcagaaaga
     6541 taaaaactgc tgagataaag ctggataaaa tcccagaaaa catatcacta atcgtctcgg
     6601 tatcgttggt caaacgagaa acgatagaac ctgctggcgt cttgtcaaag taagacatgc
     6661 ccagtttctc catattggca aaggcatccc gacgaatatc cctaacaata ctgtaagaca
     6721 cgcgcgcaaa gagaagattg ccgacatact gaactacagt ttgtaggatg tagagaccat
     6781 agtagaccag caaaacggtc acggctagtt ggttaagatt gctgagatac tggtcgataa
     6841 agtgggaagc cacaagggga atgacacttt taatgaccgt cgtcgctagg agaaaactga
     6901 gtgccaaaaa ggtaaggagt ccataaggct tgagatagga catcaagcgc ttcaatacag
     6961 tccattgttc ttgtttattc tgcatcttct tctcccttca tttccagctg ctgagactgg
     7021 taggtttggg cataccagcc atccaaagct agcaagtctt cgtgcctgcc tcgttcgata
     7081 atttgaccat tttgcaggac taaaatcaaa tctgcatgga caactgcact caggcgatgg
     7141 gcagtgataa tggttgtctt gtcctttcgc gtctccttga ggttgtcgat aatcgcatac
     7201 tctgtcttgg catctacggc ggataaggaa tcatccaaaa tcaagatatc agggtctaaa
     7261 atcatagccc gactcatagc caaccgttgc ttttgaccac cagaaagact gactcctttt
     7321 tcaccaatca gcgtatcaaa tccttgaggc atgtctacaa tatcttggta aactcgggct
     7381 agcttagtag cttcctcgac cgctgaaagg ggcaagttag gattgccaaa gcggatattg
     7441 tctaggattg aagtcgcaaa aagaaactgg tcctgaggaa catagcccat gagactgcga
     7501 aggtctgtca gacgatagtc ccgaatatcg tgaccgttta gataaatggc gcccttatcc
     7561 acatcgtatt cacgcaagag gagcttgatt aaggacgttt tcccagagcc tgtctgccca
     7621 accaagccca gtgtttgccc ttttgccaaa ctaaagtgaa tatccgtcag tgtttcctca
     7681 ttttcaaaag caaagctgtc aatggcatac tccaaacgcc cattttcaat accatccaga
     7741 ggaaactccg ggtcttgtac aggagattcc tgagacaaaa gattttcaat ccgctggtaa
     7801 gaaaccttcc ctcgctgagt agtattaaag aggaagccga tggccataag aggccagacc
     7861 agcatatcca aatagctgat aaaggtgact agattcccaa ctgtaatctg cccttcctga
     7921 accaccaagg agccaaccaa aagcgttaaa acataggacg aaccaacaaa caagagaacc
     7981 atagggtcaa agagactatc atatttcatg gtttgcaggt tcttttggaa ggttaattca
     8041 ttgactgcct gaaaagactt caactcgtct gcctgataac cgaaagactt ggtcactttg
     8101 atacctgata cggactcctg taccttgtta ttgagttcag aaaaagcagc ttgggattcg
     8161 ccaaaggcct tatgagtctt tctccctagg cgactagtcg cataggccat gaaaggtagg
     8221 gggagaatgg caacaagagt catttgccat gagatgctaa agagcatggt caacaaagtc
     8281 accagagccg tgatagaggc atccaccgca gacatgacac cgccacctgc taaacgagtc
     8341 aaggcattga tatcattggt tgcgtgtgcc atcagatcac ccgtccgata ggtttgataa
     8401 aaggctgacg acatttttgt gaaatgctta aacaagcgag accgcatgat ctgtcccaag
     8461 caataagagg tcccaaggat atacatacgc cacacatagc gcaaatagta cataccaaag
     8521 gctgcaagta gcaagtaaaa taggctaaga aggaggtcct gctgggttaa ttgccccgat
     8581 gtgatggcat caatgacccg ccccataacc ataggaggaa tgagattgag gacggaaacc
     8641 aagatcaggg ccacaattcc gactagataa cggcgttttt ctaacttgaa aaaccaccaa
     8701 agtttttgaa taatggacat aaaatccctt tctgattgca aatggaaacc tgaggccaat
     8761 actcaatgaa aatcaaagag caaactagga aactagccgc aggctgctca aagcactgct
     8821 ttgaggttgt agatagaact gacgaagtca gtaacctaca tacggcaagg cgacgttgac
     8881 gcggtttgaa gagattttcg aagagtacaa gaccccaggt ttttcttatt cataagttac
     8941 gactgtaaca gcacccttgt catattcagc aataaagata ttggctacat tgtcatgccc
     9001 ttgtttactg aggttatcaa gcaaccactc ttcgctacga ccaatcgatt ccaagacatc
     9061 tacttgaatc acaccgtcag tcacaactgg atacttagga ttttcatctc ccatttgcac
     9121 aacgatgagt tgcccatttt gctcttgcac agctcgtttg acttgcttca tctggaaaat
     9181 cccttggcta cgaagtttga gggatacatc cgatgcagac aaaccaactg aacgacaggc
     9241 ttctgggtca atattcccat ttttgataag gagagttggc ttaccatcaa tcaaacgttt
     9301 cacaaagtga acattgttgt tgagctattt gagagtcaag accagtttga ttaaaatttc
     9361 gatataatta agtgtcattt gttcacatcc accagttcaa ttgcgtctgt cttatacaat
     9421 tcgactttct ctaacaggta cttgtctggc tcacttccgt ttagggcacg ataatagcga
     9481 tctcccacct tgataagtgc gccatctgtg tttgtggaag tattaacata gacttctgac
     9541 ttgtctactc acaaatcttt ggaaacaacc tcgatgaaat gaagtgaagt ttgaaattta
     9601 ttgttagaaa cttgattgtt ttgataagtc gtgatgctga ccaaaagcag agctaaataa
     9661 ggccagatct gaaatcatga ccaactcacg aaattcgctt ccatttttat tatggtatgc
     9721 cttgaaagca aaaaaaactg tcacagctaa tagaacaatc ccaaagccaa ccatgatacc
     9781 attttgctga ccgatttggc tgagtacata gtcataagag tagaatttca tgtattttca
     9841 ctccctttca taaaatcatt cttaattata aacgaaagag agtaattttt caaaccatac
     9901 gttggggaaa tagatctttt tttggtataa taaaatctat aatctgaatg aaaaaggtaa
     9961 ctttatgaaa cttatctcat ggaatattga ttccctaaac gctgccctaa ctagtgactc
    10021 agctcgtgcc aaattgtccc aagaagtcct acaaaccttg gtcgctgaaa atgctgatat
    10081 cattgctatc caagaaacca agctttctgc caaaggacct acaaagaaac acgtggaaat
    10141 tttagaagaa ctcttcccag gctacgaaaa cacgtggcgc tcttcccaag agcctgcccg
    10201 taaaggctat gctggaacca tgttccttta taagaaagaa cttacaccta ctatcagctt
    10261 cccagaaatc ggtgcccctt ctaccatgga cttggaaggt cgtatcatca ctctagaatt
    10321 tgatgcattt ttcgtaaccc aagtttacac tccaaacgct ggtgacggtc tcaaacgctt
    10381 ggaagaacgc caagtctggg atgccaaata tgctgagtat ttggctgaac tagacaaaga
    10441 aaaaccagtc cttgcgaccg gtgactacaa cgtagcccac aatgaaatcg accttgcaaa
    10501 tcctgctagc aaccgccgtt cacctggatt tactgacgag gaacgtgctg gatttaccaa
    10561 ccttttggca actggattta cagacacctt ccgccatgtt catggcgatg ttcctgaacg
    10621 ctacacttgg tgggcacaac gcagcaaaac ttctaaaatc aacaatacag gctggagaat
    10681 cgactactgg ctcacaagta accgtatcgc tgacaaggtc actaaatctg atatgattga
    10741 ctcaggtgct cgccaagacc atacaccgat tgtcttggaa attgacttgt aaggattttc
    10801 tatatggact acaatgcggt cattcccgag ttgcttgtat cgaatatcga acagtcccgg
    10861 tccttctact gtggtttact gggttttagg attgaatact aacgtccaga agaaaacttt
    10921 ctctttctct tgaagagtgt caactaatgt tagaggaggg aacaaaggat caactagctg
    10981 aactgaccta cccctttggt cgtggagtca atctctcctt tggcataaag gatgttccaa
    11041 aactctatca aaaagtgatg gaggcaaact atcctattta tcgtctcttg accaaaagaa
    11101 agtttcgtgt cagtgatccc tatatctatc ctcataaatt tgcagttttg gatccagatg
    11161 gctatttttt aagatttagc gagtagaata ataaaaattg ggaaaagtct ttaaagttag
    11221 aaaaaggcat attgtcaggt gtctaaaaac ttgatagtat gccttttatg atggaaaaat
    11281 cttctaatac tcttcgaaaa tctcttcaag ccacgtcaac gtcgccttac cgtaggtata
    11341 tgatactgac tctgtcaatt ctatccacaa cctcaaaaca gtgttttgag gttgtggata
    11401 gcttcctagt ttgctctttg attttcattt agtataaatg ttagcttaca atggagtttt
    11461 tgttcaccct ctcttctgtt tgttcgtttt ttaaaccaaa acactaacaa aatagttgat
    11521 ttctaaagtt atttagtgta aaataaaaac attggctcaa gcctatttaa aattgaatat
    11581 cgttttactt gtttatgtcg tgaattggca cgacgtttct acaaggtgcc ggaacaccta
    11641 acaataagta agtcagcagt gagatatggc cgtttttgcc atgtctattt aggggactta
    11701 cttagagatt aagtaggtct tttttgaata tttttaatat ttcccttaat tagtgcggac
    11761 gggaggtgaa attatcctgt gaataatttc aggaatccag ggaatttcat ccctaatttt
    11821 tgagccccta gctctttcat ttctaggctt aggctaaaat agttccccga actattttac
    11881 tctcaaaaat cccgtcatag acaataacaa gattattgtc tatgatacca ctacaacggg
    11941 aaatatttga taagactcgc ttcgctcgta atagttttat caaatatata gtattagcaa
    12001 aagggatcac tatagaaaca tttaaacaac aagtaaatta acttttagac tttaggaggt
    12061 cttatgaaat tattagaaga gcgcatcctc aaggatgggc atatcttggg tgataacatc
    12121 ctcaaggtag attccttttt aacccaccaa gttgacttta gcttgatgca agagattggt
    12181 aaggtttttg cggaaaaatt tgctgctact ggcattacca aggtcgtaac cattgaagcg
    12241 tcgggtattg ccccagccgt ttttacagct gaagccttaa acgttcccat gattttcgcc
    12301 aaaaaagcta agaacatcac catgaacgaa ggcatcttaa ctgctcaagt ctactccttt
    12361 accaagcagg tgaccagcac tgtttctatc gctggaaaat tcctctcacc agaggacaag
    12421 gttttgatta tcgacgattt ccttgctaat ggccaagctg ctaaaggctt gattcaaatc
    12481 atcgaacagg ccggtgccac agtccaagct atcggtatcg tgattgagaa atccttccaa
    12541 gatggtcgtg atttgcttga aaaagcaggc taccctgtcc tatcacttgc tcgtttggat
    12601 cgttttgaaa atggtcaagt cgtatttaag gaggcagatc tctaatgcaa actcaagaaa
    12661 aacactcgca agcagccgtt cttggcttgc agcacttact agccatgtac tcaggatcta
    12721 tcctggttcc catcatgatt gcgacagccc ttggctattc agctgagcag ttgacctacc
    12781 tgatttctac agatatcttc atgtgtgggg tggcaacctt cctccaactc caactcaaca
    12841 aatactttgg gattggactc ccagtcgttc ttggagttgc attccagtcg gtcgctccct
    12901 tgattatgat tgggcaaagc catggtagtg gcgctatgtt tggtgccctt atcgcatctg
    12961 ggatttacgt ggttcttgtt tcaggcatct tctcaaaagt agccaatctt ttcccatcta
    13021 tcgtaacagg atctgttatt accacgattg gtttaacctt gatccctgtc gctattggaa
    13081 atatgggaaa taacgttcca gagccaactg gtcaaagtct cttgctttca gctattactg
    13141 ttctgattat cctcttgatc aacatcttta ccaaaggatt tatcaagtct atctctattt
    13201 tgattggtct ggttgttgga actgccattg ctgctactat gggcttggtg gacttctctc
    13261 ctgttgcggt agctccactt gtccatgtcc caactccact ctactttggg atgccaacct
    13321 ttgaaatctc atctattgtc atgatgtgta tcatcgcaac ggtgtctatg gttgagtcaa
    13381 ctggtgttta tctagccttg tctgatatca caaaagatcc aatcgacagc acgcgccttc
    13441 gcaacggtta ccgcgcagaa ggtttggccg tacttctcgg aggaatcttt aacaccttcc
    13501 cttacaccgg attttcacaa aacgttggtt tggttaaatt gtcaggcatc aaaaaacgcc
    13561 tgccaatcta ctacgcagct ggtttcctgg ttctccttgg actgcttcct aagtttggcg
    13621 cccttgccca aatcattcca agctccgtcc tcggtggtgc catgctggtg atgtttggtt
    13681 ttgtatctat tcaagggatg caaatcctag cccgagttga ctttgctaac aatgaacaca
    13741 acttccttat cgcagctgtt tcaatcgctg caggtgtcgg tctcaacaac agtaatctct
    13801 ttgtcagcat gccgacagcc ttccaaatgt tcttctcaaa cggaatcgtc gtagccagcc
    13861 tattcgctat tgtcctcaat gccgtattaa atcataaaaa gaaataagaa aaagaggtgc
    13921 gagcctcttt tttgtttatc acaaattgat tataaataca atcaatccca attcccatct
    13981 aattgaattg gacctatttc aaattcttta aaatattatg ttccaaatcg ttaatattat
    14041 ataagaatgg taaaatatca aatgtttctc gtaaattatt cttagcctta taccaacctt
    14101 gtccatcagt aatccacata aactcaacat taggaatagc tttaatttct tcagcaatca
    14161 ttttgtaaga tctagccgtc tcatttaatt ttgaaccact tcctgaataa aaattaacct
    14221 caatcagata aagcacttgt tcatttttta tgacaaaatc aaaacgtttc acagtattcc
    14281 catcattcgt aatagcagat aaatcgacag aaaaaatttc ctctatttca ttttgttcaa
    14341 tctctttaaa taaattctct cctaaaatat acccttcagc ttcaagatag ctttgaacaa
    14401 tattttccat cgcatctcca gtccgatttt tgcgcccatt agtatccata ccaacctcaa
    14461 cacctgtaac gtagtcaact aaatttgata ctaaatgatt ttgcaataaa tcaaatatac
    14521 ctgatttttc caaaaacata gtatattctt caatactata gtttcgttta ctaaaatcaa
    14581 aatagaaatc ttttatcgga tccttaacaa taatcgtatc tctcaaacgt ttagcaataa
    14641 gtagaggcac aactttcaaa atttctggat aattttgata taagtctaaa aaatcctctt
    14701 gtatattttt actaccaata agactattca taatatttag agcaactttt atactagata
    14761 catttttata aaccttagga aaatctgtat aataagtcca gtcagctact gtgtcggtca
    14821 tcgttgacaa ccactcatca aaatttctag tttgtttcat tttctgcctc caacctcttc
    14881 cttgcaattt ttaaatattc tttttcagca tcgataccta taaatcttct acctaaccgc
    14941 ttcgcaacaa cacccgtagt gccactacca acaaatgggt ctagaatata gtcaccctct
    15001 ttagtagagg ctaaaataat gcgttctaac aaatactctg gtttttgagt tggatgtttc
    15061 ccagcccatt tttcaacttt ctttgttaaa gaaccggtcc agacatcttt catttgtttt
    15121 ccatcattca attctttcat taaatcataa ttgtagtaat gacgagcttt tttatcattt
    15181 tttctggccc ataaaatggt ttcagtagaa tgggtaaaat aacgacaaga taaattgggg
    15241 gcagggtttg ttttctgcca agtaatatta ttcagaattt taaaaccttc ttgttctaat
    15301 gccattccaa ctgagtatat gttgtgcaaa ctacctgaaa tccataccgt cccattaggc
    15361 ttcagaactt cttttgctag gcgaatccat ttacgattaa actcatgttt ttcttcgaat
    15421 gaagaaattt tatcccaatc tcctttatca acagaaacaa cttgtccccc agaattagat
    15481 attccaccat tacttaaaaa ataaggtgga tcagcaaaaa tcatatccat actttctggt
    15541 ttcatttttg ataagaactt gaacgtatct gaatgaacaa gaatcatctt atttttattg
    15601 tagtatggtt ttgtcataag aacacctcca tacttatatt cgttattttt cataatttgt
    15661 gactataatt tcagaaattt ttcctcgact tgaagatttt gctccattag ttcgggtagc
    15721 ttcaacataa tgtatattaa aatccttata caactcctct actaaagcac tagaagaatt
    15781 tgataacata acataagctc ctgtatcact caatctctta aaggcatctc ttaatcttac
    15841 ttgatctgca aaagagaatc cctcatgagt ataagacgta aatgcactcg tctcagacaa
    15901 tggaatatat ggagggtcaa aatacacaaa atctcctgtt cgaacatcta caattgcctt
    15961 ttcaaaatct cccactttaa tttctagttg attgttattt atataaactg aaatagcaga
    16021 tatcaattcc tcatcaacaa ttttaggatt cttataacgt ccatatggaa cattaaattg
    16081 attcttagaa ttcacacgat atagaccatt aaagttcact ctcaacatat atagaatacg
    16141 tgcagctctt tgtacttcgg acatcatatc tattctttca tcacgatctg cagaacgtaa
    16201 atctaaataa tattcttttg aattatattc ctgatgaact ttcaaaattt caatcaattc
    16261 ttgaggattg tccttaattt gttgatagca atttattagt tcagcgttaa aatcattaat
    16321 aactgcatct ttaggagcca aatcaaaaaa taaagctcca cctccaacaa aaggttcgaa
    16381 atacctgtta taggttttag gcattaattc tctaataaca ggcaataatt gtcttttacc
    16441 acctgtccat ttcgtgaacg gttgtaaagt aactttcttt atttctttta tcttcatgct
    16501 tttaattata ccatagaaat taaaacacaa ctcttgtatt ttctaccaca ttactaaatt
    16561 ttctatttta gaattaaatc atatcaatat caaaaaatga gtaaggcaaa tcttataaat
    16621 tccaaaattc acctcactct attaaattac tctttatatc cttacctgtc tttcttctga
    16681 ccgctggcct gtgacaaaca tggtaaaggt tgctttacag acatttctgc cctcttgatt
    16741 ggtgatatcc acatccatca cacaggttgt acggccttga tggacacatt ctcctttaat
    16801 ggtcaataca tcgtcgagtt ttcctgcctt aaggtagttg atagaggatt ggagtgtcac
    16861 cccatcaagt cccagcgaga taaccaccaa accactgatt tggtcacata gcgtgaatag
    16921 atagccacca tgggcattgc catagtagtt gagcgacgag ttcactactt tggtcgtcac
    16981 cacaacgtga ccatctctca ttttttcaat ttcgtaattt tcaaaggcag atatagcgtc
    17041 aaaatgaaag tctttcatcg tttcctcctg atatttcaaa cgacactatg atactacttt
    17101 ttataggact gtgcaaggag aaagctccta gtctagtgaa attccgacat gttccacaaa
    17161 gcgcataaag gctgtctgcc cttgttctgt ctgcttgtag actcctgcat cctcaagtac
    17221 acgcacaaag atagcaccca cagagtcctt gacgattgca agggcttttt ctttatccgt
    17281 taggtctgga tgttgggatt tgagttggtc tgcccactcc tgatgataat cggcaactgt
    17341 aacagcttct cctacaagat agctagcgac ttgctccact tcttctttca gacgtggtgg
    17401 caagattgcc aagcccatga cctcaatcaa gccgatattt tccttcttga tatgttggac
    17461 atccttgtgg ggatgataga tgccatcagg atgctctgct gaagtctgat tgtctcgcaa
    17521 gaccaagtcc aactcaaact gtccatcacg cttacgcgct attggtgtga tggtgtgatg
    17581 cggtgtcccg tctgtctctg ccaaaatctg cacactagaa tctgaatact gacgccattc
    17641 ctggaaaatc ttatcagcta agttaatcaa atcctctttg gaatccgaag tcaagcgtag
    17701 gacagacatt ggccacttga taattccagc cttgacctgc tcaaaaccag caaatcggaa
    17761 ggtcttttgc aagggagcca attccatagg aaatacgtga cggcctccct gataatgatc
    17821 atgagttaga atagagcccc ccacaatcgg caggtcggca ttagatccag caaaatatcc
    17881 tggaaactgc tctacgatag ccaacagacg ttcaaaactc tgacgactaa tggccatggg
    17941 acgatgctgg ccatctaaaa agatacaatg ctcattaaag taagcatagg gcgaatactg
    18001 gaacccccat tcctgaccaa ccatttcaaa acggataatc cggtggttgc tgcgagctgg
    18061 gtggttgacc cgaccatggt aaccctcatt ctctaaacaa agttgacact gaggataatt
    18121 actagcttgc accaacttgg ctaccgcaat ctctttcgga tccttttcag gcttagagag
    18181 attgatggta atttcaagtt ctccataatc agatggaata cgataagcga tatttttagc
    18241 aatggccttg agtttgatgt agtcattttt ccgactgagt tgataaaaat cctctatcgc
    18301 ttgctcagga gagtaggcat aggcttccca gaagtcacga ttgacctgac tcggacaagg
    18361 agtcaccaag tccatcagtt cagtaccaag gatttcacgc gcagtctgac tatcctcaat
    18421 cgtctctaat cgaacggctt cctcaactag ctggtccttg aggtcaatca atttatccag
    18481 attggtctca acttccaaaa caccttctcc cactcgtgcc aaaacacgat tggtcaggta
    18541 gattcgatcc atttcctcaa atgaactttc agaaatgaca tgtgttacaa atttatctac
    18601 taaggtcact atagagcctc cttttgacta gtcaaggacg cgagtgccac ctgcaacttc
    18661 agcgatatag aagcttggag cgtatccaac tacttcctcg tagtgtttgc ctacagcttc
    18721 cttaaaggcc tcaacagtat ctttttgaac caaggcaatg gcacagccac caaaaccagc
    18781 ccctgtcata cgagcaccga gaactccttc ttgtgcccaa gctgtgtgaa caagagtatc
    18841 caattccaaa ccagttactt cataatcatg ctccagagaa acgtgtgacg cattcatcaa
    18901 acgaccaaat gtttccaaat cacctgcttg aagggctgct tgagctttaa gggtacgttg
    18961 gttttcaagc acagcatggc gagcacgttt caaacgattt tcatctttaa tcagatagct
    19021 atattggtca acggcccact cgtccaattc acccagggtc tgaatatcca aggcaacttg
    19081 caattcttcc actgcttttt cacactcagc acgacgttca ttgtatttag agtccgccaa
    19141 ttcacggcgt ttgttggtgt tcatgataac aacgacattg tccttcaaat caagtggcac
    19201 caagtcgtat tctaaagtat tggtatctaa gtaaatagca cgttggtcag cccccatacc
    19261 aatagcaaat tggtccataa tgccagaatt tactccgata aagttatttt ctgtttgttt
    19321 tccgatttta accaaatcga gacgctctaa ttttaaatca aagagatgct ctgccactac
    19381 ccctgtcaag agttcaaggg atgctgaaga agacaaacca gcaccatttg ggatattccc
    19441 ataaacataa aaatcaaaac ctttgtcaat cacgtgccca gcttcttgca agaaatgaag
    19501 gacacctttt ggataattgg tccagttgtg ctctttttca aacttgaggt cagcgagagg
    19561 cacttcgata atgcccttgt cctcaaagtt agctgagtag aaacgcaaga cttggtcatc
    19621 acgcttgcga gctgcaccat aagttcctaa ggaaatagca gctggaaaaa cgtgcccacc
    19681 gttgtagtct gtgtgttcac caatcaaatt aatacggcct ggtgaaaaga aagtttggtc
    19741 tgcttcttga ccaaaaacag caagaaagtc tttgcgaaga gtttcagcag taagatgttg
    19801 tgtcatatga tttctccttt gactgtccgt taagccacct taacgtgtaa tcgttttctt
    19861 ctattgtatc caagggattt cccaaggtca atccttttta ctaaaatttt actaaactat
    19921 cagtaaaaag cagaaaaata tgatatacta atctaatcaa ggaggattta tggctacctt
    19981 aaaagacatt gcacagctag cctctgtctc tatcgcgacc gtatcccgcg tcctcaaccg
    20041 cgaccagagc ctatctgtta cagaagaaac cagacaccgt attttaaccg ttgctgaaga
    20101 gctgggctac accaagcacc tcaagacagg cgagtcccat aaacccaagc aaaagattgc
    20161 cattattcaa tgggtcagcg aacaagggga gctggacgac ctctactact accagattcg
    20221 cctaggaata gaaaaaagag cccaagagtt ggactacgat atcttgcgct attttaatga
    20281 ccaccctttt accctaagcg aggaagtgat tgggattctc tgcatcggaa agtttagtcg
    20341 agctcagatt tctgcctttg aagaatacca aaagcctctt gtatttctag acagcgatac
    20401 actttccctg ggacatacct gtattattac ggacttttac actgccatga aacaggttgt
    20461 cgattatttc ctcagtcaag ggatggaccg tatcgggatt ctaacaggcc ttgaagaaac
    20521 aactgaccaa gaagaaatca ttcaggacaa gcgtctagaa aacttcaaaa actacagtca
    20581 agcgagggga atctatcatg atgaactggt ctttcaagga agatttactg cccagtctgg
    20641 ctatgactta atgaaggagg ccattcagag cttgggagac caacttccgc cagcattttt
    20701 cgcagccagc gatagtttag ctatcggtgc cctccgtgcc ctccaagaag ctggaatcaa
    20761 cctgccagat cgcgtcagcc tcatttccta taacgacact agtctgacca aacaggtcta
    20821 tcctcccctc tctagtatta cagtttatac tgaagaaatg ggccgagcag gtatggatat
    20881 tcttaacaag gaagtcctcc acggtcggaa aatccctagc ctgaccatgc tgggaaccag
    20941 actgacatta agagaaagta ccctaaatca agaataggat aacataaaaa acgaatagga
    21001 gttttagaac tcctattcgt tttttattcg attacaatca tagacttaat ggtcttacgt
    21061 tcatccatat ctttgtaggc ttggtcgata tcttccagtt tataacttga agtaaagacg
    21121 cgacctggat tgatatcacc atcaaggacg gcttttagta aaaattgctt atcgtatgtt
    21181 gtagcagaag ctgccccacc tgctacagag atattttgca taaatgtcga accaagagca
    21241 cgattattat agtgtgggac tcctacaaag cccatacgcc ctccattatg aagaacacct
    21301 agcgcctgtt ctatagcaac ctccgtacca acacattcaa gtgctgcatc tgctcctcca
    21361 ccgaggattt cacgcacctt ggtaattcct tcttgaccac gttctgcaac aacagctgtc
    21421 gcacctgact ccatagccat cttttgacgg tcttcatgac ggctcataag gataatttgt
    21481 gatgctccac gcatcttagc cgcgatgaca gcacattgac caacagcccc atcaccgata
    21541 acaacaacct tgtccccttt ttgaacattt gcaacacgcg ccgcatgata gcctgtcggc
    21601 atgacatctg caagagtcaa aagggacttg agcatccctt ctgtatagtc agaaggttga
    21661 ccagggattt taaccagcgc ccagtttgca tagtggaagc gaatatattc tgcctgaaaa
    21721 tcacccccca aattattgcc aatatgattg tcgcaagaac cgtcaaatcc agcaagacag
    21781 gcatcacact caccacatcc atgtgtaaaa gggacaatca caaaatcacc tggtttcacc
    21841 gtcgtaatgg cttccccagc ttcttcaaca atcccaatcg cttcgtgtcc actatttttg
    21901 tgtccagctt tcgtttctgg attacggtac ctccataaat ctgaaccaca aacgcacgca
    21961 cgaaccacac gaataatcac atcatccgct tctattattt gcggacgttc aatgctagca
    22021 agtccaacct gacctgcctt tgtatatact gctgatttca tttaaaattt tccttcctta
    22081 taaagtttaa ttttgagatt taaacgattt aaagctgtct gtagctgaga caagcgctcc
    22141 tctaattttt gcttttcctc ttctaaaata ccaagcctct cctctctcgt ttcatctccc
    22201 ttttggtaga gcgacatata gtcaactaaa ctatctacag agacacacgc cgaacgaaaa
    22261 cacttaataa attccagcgc ttcgatatcc tgatcttgaa aatcacgaat cccagtagca
    22321 gtacgagtaa tcggtggcac aagaccaacc cgttcataat accgaatcgt atccgctgaa
    22381 attcccaaca aatcactggc agatttaata ttcacacgct aacctcctct catttcattc
    22441 actgaattca cgctattcta actcacttat cttattatat aactttgagt tgactccaag
    22501 tcaagcattt tgtatctaat cgaaaaattt ttatcattaa caatcatata tctgaagttt
    22561 atacaatgct cttctcttac caatttttga aatatttaaa taataaagaa attactctat
    22621 tccaaataag atagtaccca agtatttttc acttttttct aatgttgatg ctcataactc
    22681 cgttccaagt cacacacctt tcgcttatgg gtttggtgag tttctaggtc agcatcaatt
    22741 tcaatggtaa tattttgaaa accacaatct tttaggaaaa ttcgaataga ctctttacaa
    22801 gtttccatat attccatttc ttttagacaa acatggacaa tggcattttt ttccaaagca
    22861 tccatagtcc agagattaag ctgattaagg ctggccacat tgtccaatcg ctccaggcca
    22921 ctctttactt gcttgatatc aagaccttct ggcacagcat ccaagaaaat cttgagtgta
    22981 gaccaaaaac gtggaagggc ttttgaaaga ataaagaaag aaatgacaag ggacaaaaga
    23041 ggatctagga tataccagtc cgtaaatcga agaacaatcg ccatcaggat aacagctacc
    23101 caccctagcg tatcttccag aaaatgcaga ctcagaatag actcattctt tgtctttccc
    23161 ttaccaacca ccagactcgc taacagattg atagtaatcg caataattcc taaccagaga
    23221 atcccctcat cattgactgg ttgcggatgc aaaatcttcg tgacattttc caaaatgact
    23281 agaacagagc ccgttacgag aatcacagct gttaccaagg ctcctagcag gctaaaccgc
    23341 ttatagccca aggtgtactg attgtcttct tcacgattgg agattgtttc tagaaaagct
    23401 gacattccaa ttgcaatcgc atctcccaag tcatgcacag agtcagcaag aacagcgcta
    23461 gaaccaaata ctccacctgc aataaactca acaatggcat aagtcaaatt taagaaaaaa
    23521 gccacccaaa cagcatattt tgccttcata tttctcattc ctttgttata atagatttat
    23581 gaacaccttg ttcattatca ttatccacta aaactcaaag aaaggataga agcaaaacgt
    23641 cagctttatt cagttctgaa caatttgcct taagtgtcca tatgactaac attgaccgcc
    23701 gtatcagcaa aaccaaaaaa gccatctatc aagcttttat acaacttttg aatgctaagg
    23761 gctacgaggc cactactgtt caggatatca ttgatctcgc agatgtggga cgatccacct
    23821 tttactgtca ctatgaaagt aaagagcttc ttctggatca gctctgccgc tacctcttcc
    23881 atcatctttt tgaaagagag caagccattt caaccgaaga ctacctcgcc cacctctttc
    23941 tgcattttca gaaaaaccaa gaccatatcg ccagtctact attctccaaa aatgactatt
    24001 tcctccgtca actacagaga gagcttgagc accacgtcta tcccatgctg gctgctgatt
    24061 tgaagcaaac tcacccaagt ctacctactt cttacctcca acattttgtc gtaactaact
    24121 ttatcgaaac attgacctgg tggctcaaaa aaggtcaaga tttcacagac caggaagttg
    24181 tccaatttta tctagacctt ctcattccta aaaattgaat atagagtaaa acttcagttg
    24241 tcttatttct aggttactga gttttttatc ttttcaacaa caaaagagga cccgccgatc
    24301 ctctttttca tactataaat ccttgattat caactatatc tgttttaatc gaaatctcaa
    24361 aacagcactt tcaaacatct tttcctagtt aagtaaatca gtattctgct tagctgcctt
    24421 gctccattga taccaaccaa ctagactgtt aatgagataa attagatatt tcccttgaat
    24481 ttgcaggctt tctccccacc agagatagat tgaaaagaca ttggtagccg cccagaatat
    24541 ccactgttca cggtaaacag ctgtcatgag gatttgccct accccattgg ttgcatctgt
    24601 gattgaatca cgatagggac gattggcacc aatagactga taaatgaagc caaaggccaa
    24661 ccaccaaagc acactaatgg aaagatactt tgtccagccc ttgccgtcca gtttacgcgc
    24721 gacaaactcc tgcttttcct tcttaaactg tgcctgataa atccaaacta gaagtccaat
    24781 tggctgcatg actgtgaagt aaagtgtcgt cagcacctca ccataaaagc ctttctgtag
    24841 ggccaaaata aggtaaataa cagagttaat caagccaaaa agataattac ttgctcgacc
    24901 ttccgataca aagattacac agataatccc tgtcaagcta caaatcatcc caatccagtc
    24961 aacaatacga tgttcgtaaa ccaactccag ccagagagga aaacttccta aaaccagcaa
    25021 ataaatccac tgggcaaaac tacgatgggc aaagaggtca tcccagatag ccttcatagt
    25081 tcctgaaaat cctaaatcag ccatagccgc aaccatacga cggtaaccac ctgacatttc
    25141 acctagggtt gttttgatat tttcaatttt cttttgcaaa taagtatgca tcatttctcc
    25201 ttttgttttt aaagagccgt gtctggatag actttcggac gcaacgctct attagataat
    25261 gaactgccta tacacaagat ttctaacctt agtcgacatg agctgaaacc tcttatttgt
    25321 taagtagttc acaaaatatt atacacctat tttatgaata gtcaactgtc tttacagtaa
    25381 aattttagaa aatcatgaaa attttctctt tctttccatt ttaagtgaca ttcagtcatt
    25441 ctcacatcaa aaaagcccag acgaaattgt ctgagcattc ttttatctag tcgtttaagg
    25501 aagttgagtt cagtatgttt aaagtctctg tcccatcatt tcttcaacaa accttgttct
    25561 tggagaaact ccttggctac ttgctttgct gacttgcctt caacaccgac ttggtagttg
    25621 agctggctca tctggctttc tgtaatctta ccagccaatg tattaagaac tctttccaac
    25681 tctgggtgtt tcttgagaag agcttctttc atgagtggag ccccttgata aggtgggaag
    25741 agttgcttgt catcttccaa gacctgtaaa tcataacgct ccaattccgc atcagtcgaa
    25801 taggcatccg tgatttgaat atcccctgac tgaattgcct gataacgaag agctggctgc
    25861 atagtcgcca cattgagatt gagaccatac attgattgca agcccttatt tccatcttca
    25921 cggtcgttaa actcaagcgt aaagcctgcc ttcagctgcc cttccacttt tttcaaatcc
    25981 gaaatggtct tcaagccata ttcttgagca atctttttcg gaacagctac agcataggta
    26041 ttttgataag acataggttt gagataggct agatgatcct gcttggcaat gccatcacgc
    26101 gccacttgat aaacctgctc tggctcatga ctcaccttgg gtgatggttg aagcaaactt
    26161 tcagtcaccg taccggtaaa ttcaggataa atgtcaatat cacctttttt cagagcttca
    26221 taaaggaaac ttgtcgtccc aaaattcggt ttaacagtcg cagtcatgct ggtattttct
    26281 tcaatcagca atttatacat attagccaaa atttctggtt ctgggcctat tttcccagca
    26341 ataatcaagt tttccttctc tttttgaacc aaaagagctg gactataaga cagacccagt
    26401 aataaagcca ccaaggcaaa accagagaaa atcgtccgta attttgcttt ttccattact
    26461 tttagtagga agttaaaggc aatagctagc actgcagaag aaagtgcccc aatcaaaatc
    26521 agactggcat tattacggtc aattcccaaa aggataaagg aacctagtcc ccctgcccca
    26581 atcaaggtcg ccaaggtagc cgtaccgata atcaagaccg ctgccgtccg aattccagac
    26641 atgataacag gcatggcaag tggaatttca aacttcttga gacgctccca tctggtcatc
    26701 ccaaaggcaa tcccagcctc ttgcagactc ggatcaattc ccttcagccc agtaatagta
    26761 ttttgtaaaa tcggaaaaat cgcataaatc actagagctg tcaaagccgg caaggtccca
    26821 attcccatca aagggataaa gagccccaac aaggccagag acgggatggt ctggaaaata
    26881 cctgcaatct gcaagaccca gtcggccagc ttctcatgat agcgaagaaa aacagccaag
    26941 ggaatcgcaa gcaaaatagc tagtaacaag gtcaaaagtg acaactgcaa atgttgagat
    27001 agagctgtca accaatcact aaaacgatcc tgaaaagttg caattaaatt agtcatgaac
    27061 actacctcca aacaagtctg ctacaaagtc tgttgcaggc acttttaaaa ttgtctcggg
    27121 attcgctacc tggcgaattt ctccatcctg caagacagca atacggtccg ccaacttcaa
    27181 ggcttcatcc gtatcatggg ttacaaaaat cgttgtcatc ccaaactctt tatgcaattc
    27241 ttttgtcaga acctgcaact gttttctcga aatagcatcc aaggccgaaa agggttcatc
    27301 catgaggaaa atcttgggct gaccaatcat agctcggaca ataccgaccc gttgctgttc
    27361 tccaccagat aattcactag gtaagcgatg cccatactca gctactggta aaccaacctt
    27421 agccaaaagc tcttctgttt tcttcgtaat ttcttccttg ctccacccct tcatttcagg
    27481 aatgagagca atattttccg caactgttag atttggaaaa agagcaatag cctgtaaaac
    27541 ataaccagta gaaagacgaa gttcacgctc atcatagtct ttgatgcgct tcccatccat
    27601 ataaatattt ccatcagttg gttccaaaag acggttaatc atcttgagca tggtcgtctt
    27661 acctgaccca gaaggcccta ctaaaaccat aaattcccca tcctcaatct gtaagttgac
    27721 atctctcaag acatcctttt ctgtgtagca tagtgctaca tttttgtatt caatcattct
    27781 ttgtcctcat ttaaaacttc cctcgattag tcaagtcttc taccttaggc atgacttcct
    27841 tattatccca atgctccaca attttcccgt tctctaaacg gaagatatcg tactgggcat
    27901 aagcaacgcc atcaatctga gtctgaccat agctaaccac atagtttcct tgtcctaaga
    27961 gttggaaaac aaagtcaaaa gtgacactat attcagccac atagttttta taagcagcac
    28021 ttccttgtcc aatatcatga ttatgctgaa tcaaatcgtc tgccacataa tcactccact
    28081 gctctagctc cccattttgg aaaatttctg tcaagaaacg gcgaaccagc tttttatttt
    28141 ctgctttctt gtccaaatcc ttgatttcaa aatctccaaa aatttgatct agttggtcat
    28201 tttcaggtgt tcgatagtag tcaatgacat cccaatgctc aacaatacga ccattctcat
    28261 ccgcacggaa agtatccgtc gtcacccatt gagcttctcc accattcaga tattgatgaa
    28321 catgaacaaa gaccagattg ccatcctcaa tggtgcggac aatcttaatc tgacgctctg
    28381 gatgacgctc aaagaaatct gcaaagaagg ctgcaaatcc ttctttcccg tcaggaacac
    28441 ctgtcgaatg ttggatatag gtatccccta cagactgggc ttgagcctca gcaactcgtc
    28501 cgtcttgaat ggcatggatg tataggttgt gagcattttt cacttgttgt gacatattct
    28561 aaacctcatt tcccttctct ttcagattcg ccaaaattct ttcttgaaaa ccttcaaatt
    28621 ggtgaatttc ttcctctgaa aatcctttgt aaaagatagt atccaatttc tgactgacac
    28681 gatgccccac ttctttctgg gacttgccta actccgttaa aactaaatac ttcttacgct
    28741 tgtcttttcc acacggacta acaattacaa gcttttgttc ctctagcttt tttatcatag
    28801 tcgtcagcgt attattcgca agtccagtcg caagcgcgat atctgtcgca gttgcgcagc
    28861 cagtttcact attccataaa accgctaaaa tcttgccctg ttcaccccta taaagagcct
    28921 caggatcttg actcagtaac ttttgaaaaa tccgcccatt caacaaacga atatgatggg
    28981 ctagcaaatg accatctttc ataacacctc caatttattt cgatatcgaa atgaataaaa
    29041 caattgtaac actcatcgtt ctaactgtca actatttcga tttagaaata atttttgata
    29101 attatccaca ccaccatact ccggctcaac taacttttaa cgagagtttc taaactcctt
    29161 cgtcctccag tctacaaaag ccttccatcc gtactatcct atattttatg aggggacaca
    29221 tttttcctat cagagcattt attttaaaga tagaagtaaa tcataattgc ttccatctgt
    29281 tcttttatag tatattgaag ttggactagg gcactgtatc ttctaaaaca ttgatagaaa
    29341 gcgatttgaa tttcccaatc aatttgctcg tatttatagc attttgaaac tagaatagga
    29401 cgccatgact gctaaaagat ttctataaat tcatttgatt ttcctaatca atttgttcat
    29461 gtcttatttc atctcgctat aatttcacct taccctatct ttttcgtagc acccttcaaa
    29521 cagcctatcc cctaccgttt gacgattcct cacttcactc cacttccatt acagaagttt
    29581 cttcactact atggtctcgg ctgacttctc atgattcctt gttactacta tttgaacgct
    29641 cacgagatag gtcttataaa aaatgctttg atccacaatg gaatcaaagc attttaaaga
    29701 gttcctcata cataagcgca gaagtcgcag ttcctctgta cttggcttct tctcttttga
    29761 taaagctagc caagttgagc aactcaggtg ctggatgttt gggatttagg agcaattcac
    29821 gattgaccag gcctgagaga cgaactgcct gcaattgctc atttgtagta ggcagttttt
    29881 tagtagtctc taggagagca gcaactaaat cttcactcaa atcatgtcga acatgattgt
    29941 aaagatcttt tataaggctt tctaggtttg gttctaccat ccctaccacc tcccttatgg
    30001 tttaataatg tttaatcaaa tcaaccgttg aacgatccaa tttcttcacc aaggcttgta
    30061 agaaagcttg cgcttctagg aagtcatcca ttgcatagag ggtttggtga gaatggatat
    30121 aacgagcgca gacaccgata gttgttgatg ggacaccacc atttttcaga tgagctgcac
    30181 ctgcatctgt tccgccttta ccacagtagt attggtactt gataccagct tcttcagccg
    30241 ttgtcaaaag gaaatccttc atccctggaa gaagcaagtg acctggatca tagaaacgaa
    30301 tcaaggttcc atctccaatc ttgccttgac caccgtagac atcacctgct ggtgagcaat
    30361 caactgcgag gaagacttct gggtcaaact tggttgtaga ggtatgagcg ccacgcagac
    30421 caacttcttc ttggacgtta gaacccagat agagttcatt gccgagtttt tgacctgata
    30481 aagcttcagc tagctcgctt accatgagga caccgtagcg gttatcccaa gcttttgaga
    30541 tgatattttt ttcattggct gtcaaaattg cagaactatc tggtacgatg gtatcaccag
    30601 gacggatgcc aaaactttct gcctcagcct tgtccgcaaa accaccatca aaaacgatat
    30661 cggcaatggc tggcatggtt ggtcccccct ttccacgagt caaatgcgga ggaacagaac
    30721 ctgaaatcac aggaatttca tgaccatcac gagtcaagag tttgaaacgt tggctgctaa
    30781 ccaccatggg gttccagcca ccgatttcta cgacacggaa ggtaccatct agcttgattt
    30841 cgctgaccat aaaaccaact tcgtccatat gagaagcgac caagacgcgc ggtgcatcca
    30901 cagcttctga atgtttgata ccaaaaatac cacccaagcc atctgtcacc acttcatcca
    30961 catgcggtgt caacttttca cgaagataag cacggacagg cgcttcatga cctgagactg
    31021 cagcaagttc tgttacttct ttaatttttg aaaataatgt tgtcatttca gttccttctt
    31081 tctttcatcc attttaccac tttttatagg agaaggatag tgggaaggtg gatttctaag
    31141 ttagtatctt agtcctgctc tatcttagaa aaggatagta ttctcttgca tgtagtgcaa
    31201 aatctagtaa acattccaaa attaactcga atatttattt ccaaacaaaa aaacaataca
    31261 ccatcaaagt tgtttagatt tttcatgaaa tttacagaaa atagttgact tccctttctt
    31321 ctttctttaa atatatagtt ggttgagttt ggaatagtac gctgtagctg ctaaaacatt
    31381 tctagaaatt aatttgactt tcctaataga gttgttcata tcttatttca atttactata
    31441 gtacaaaact agaaaaggaa aaaatcatga ccaaaacaat tcttgttaca ggtgggacta
    31501 gctacattgg ctcccatacc gttaaagctc ttttaaatgc tggctatcag gtgcatgtcc
    31561 tcgataatct ctccacagga aatcgagcgg ctgtggatag tcgtgctagc tttaaagaac
    31621 tggatgttta tgatgctagc gccttaaagg cttacttaga agaaaatcag attgatgctg
    31681 tcctccattg tgcaggtgaa attgttgtga gcgaaagtat tgaaaatcca agtaaatact
    31741 tcactgccaa cgttgctggt atgaaccaag ttctcaaagt cttatctgaa gttggcattc
    31801 aaaaaatcat gttctcttcg actgcttctc tctatagaaa taactgtatt gacaagccgg
    31861 tgactgaaga taccctgctc gaccctgtca acccttatgc agagacaaaa ctgatgggcg
    31921 aacgaatgat ttactggatg gccaatcgct acgactggaa atatgttatt ttccgttact
    31981 ttaatgcttc tggggctgaa atggatgctt caaacggtct gcgtgtgaaa aatccaactc
    32041 acatcattcc aaatatcaac aagaccgcat tgggacaaaa tgatagctta aaaatatttg
    32101 gagatgacta cgatacacgt gacggttcat gtattcgaga ttacatttat gtcttggacc
    32161 ttgcataggc tcatgttaaa ggaatgaact acctatttca agaagacagt tcttctcaaa
    32221 tctttaactt aggaactaaa aaaggctata ctatcaaaga aatctttaaa actgctgaag
    32281 aattactaaa ttaaaaaatc ccacacgaga ttgttgctcg acgtgctagt gacccagcca
    32341 gtgtcctagc agatgcttca aaagctaaac aatatcttga ttggacggct agctactccc
    32401 tcgaagatat tattttatca gattaaggta aaaacatttt agaataggat aacaaaggag
    32461 aaagtcttgt tgctctctcc ttgttatatt tattaaattg tcagaaattt tattgacaga
    32521 ttagaaaaat aatgttacat ttatatccgc agatatcttt cgataccaaa tctacatgaa
    32581 aggacggggt atgaaacttt ctcattattt aattggctta cttctactcc tagtctttct
    32641 ctctattagc attgggacca gtgatttttc atggggaaag ctatttgatt tcgaccagca
    32701 gacctggctc ctttttcaag agtcccgtct cccaagaact atcagtattc tcctgactgc
    32761 ctctagtatg agtatggcag gccttctcat gcagactatt acccaaaatc agtttgctgc
    32821 accgagtaca gttggaacga ctgaagccgc caaactggga atggtgctga gcctttttgt
    32881 ctttccatcg gctagtctga cccaaaagat gctcttcgct tttgtttcat ccatcgtatt
    32941 caccctcttc ttcctagcct ttatgaccat ttttactgta aaggaaaggt ggatgttgcc
    33001 tctgattggg atcatctata gcgggattat cggctcagtc acagaagtta tcgcctatcg
    33061 tttcaatctg gttcagagta tgactgcctg gacccagggc tccttctcca tgattcagac
    33121 ccatcagtat gagtggctct tcttaggcct catcatcctg ataaccgttt ggaaattatc
    33181 ccaaaccttc accatcatga atctggggaa agaaaccagc gagagtttgg ggatttccta
    33241 ctccctactt gaaaaactgg ccctctttct ggtggcgcta acgacaagcg tcaccatgat
    33301 taccgtgggt ggcttaccat ttctcggagt tatcgttccc aatcttgttc gcaagcgcta
    33361 tggagataat ctaagtcaaa ccaaactcat ggtcgcactg gttggtgcca atctagttct
    33421 ggcttgcgat atcctatccc gagttctgat taggccctat gagttgtctg tcagtctctt
    33481 gctaggaatc atcggtagtc tcgtctttat cctacttctc tggagagggg gacgaaaaga
    33541 tgcagactaa aagcaaacat accaagctct tctggattct cattattctt gccatcggag
    33601 cttgtcttct ctacttttgg cccatcactc acttgtcagc ctttgcttgg aagttgcgtt
    33661 cccaaaagat catcgtttat ctcttggtag ccatcgcgac tgggatttcg accattagtt
    33721 ttcaaaccct gacggaaaat cgcttcctga cgcctagtat tttgggaatt gaatccttct
    33781 acgtcctact acaaacccta ctactggttt ttgaaagcaa gtttcttcaa cttggcaaat
    33841 cccctatctt agaattccta gtcttacttc ttgtccagtc cttcttcttt ctcgccttac
    33901 aaggttactt gaagacactg atgaagcaag acctggtctt catcctgctg atctgtctag
    33961 cgctcagaag tctctttcga aatatcagca ccttccttca agtcctaatg gatccaaacg
    34021 aatacgataa actgcaaaat agtctttttg cctcctttca acatcttaac acttccatcc
    34081 tagccatcgg ttctctgatc atcctcgctt tgacaatctt tttctttcga aaagcagtcg
    34141 ttctagatgt cttgcacctg caaagagaaa cggctcagat attgggactc gatgttgaaa
    34201 aagaacagaa agagctcctc tggggaatcg tgcttttgac ctcaacggcc actgccttgg
    34261 taggacctat ggccttcttc ggctttatgc tggccaacct cacctacctg attgtcaaag
    34321 actatcagca caagttactc tttatagtgg ccattctggt tggatttatt agcttaacct
    34381 tggggcaagc cttgattgaa cgagtctttg cactggaaat tcgtatcagt atgatcattg
    34441 agagtgtggg tggcttctta ttctttatct tactatatag gagggctcgt cagtgaaact
    34501 ggaaaacatt gacaaatcca ttcaaaaaca ggatattttg caaggcattt cgcttgaagt
    34561 cagtcctcaa aaactgacag cctttattgg tccaaatggt gctggaaaat cgactctcct
    34621 ctccatcatg agcagactaa ccaagaaaga tcagggagtt ctcagtatca aaggacgtga
    34681 aatcgagagc tggaattcgc aagaactggc ccaagaacta accatcctaa aacagaaaat
    34741 caattaccaa gccaaattga ctgttgaaga actggtcagt tttggacgtt ttccctacag
    34801 ccgaggtcga cttagatcag aagactggga aaaaatccga gaaactctga actatttgga
    34861 actgaccaac ttaaaagacc gctacatcaa tagcctgtca ggggggcaac tccagcgcgt
    34921 ctttatcgct atggtactgg cccaggatac ggactttatc ttgctggacg aaccactcaa
    34981 caatctcgat atcaagcaaa gcgtcagcat gatgcagatt cttcgacgac tggtggagga
    35041 actcggcaag accattatca tcgtcctcca cgatatcaac atggccagtc agtatgcaga
    35101 tgaaattgtc gccttcaagg acggccaggt ctttagcaag ggaagaaccg atcaaatcat
    35161 gcaggctgac ctgctcagtc aactttatga gattcccatc acgctagctg atatcaatga
    35221 caaaaagatc tgtatctata gctagtaaca taaaagctca agttagagaa ccttcagtct
    35281 cttagtcaat aagattaaga gactccctaa atcgttatca cattttaaaa aggagaaatt
    35341 atgaaaacat cccttaaact ttatttcact gccctagtgg ccagcttctt gctcctactt
    35401 ggtgcatgta gtacaaactc aagcactagt cagacagaga ccagtagctc tgctccaaca
    35461 gagataacca ttaaaagttc actggacgag gtcaaacttt ccaaagttcc tgaaaagatt
    35521 gtgacctttg acctcggcgc tgcggatact attcgcgctt taggatttga aaaaaatatc
    35581 gtcggaatgc ctacaaaaac tgttccgact tatctaaaag acctagtggg aactgtcaaa
    35641 aatgttggtt ctatgaaaga acctgattta gaagctatcg ccgcccttga gcctgatttg
    35701 attatcgctt caccacgtac acaaaaattc gtagacaaat tcaaagaaat cgccccaacc
    35761 gttctcttcc aagcaagcaa ggatgactac tggacttcta ccaaggctaa tatcgaatcc
    35821 ttagcaagtg ccttcggcga aactggtaca cagaaagcca aggaagaatt ggccaagcta
    35881 gacaagagca tccaagaagt cgctactaaa aatgaaagct ctgacaaaaa agcccttgcg
    35941 atcctcctta atgaaggaaa aatggcagcc tttggtgcca aatctcgttt ctctttcttg
    36001 taccaaacct tgaaattcaa accaactgat acaaaatttg aagactcacg ccacggacaa
    36061 gaagtcagct ttgaaagtgt caaagaaatc aaccctgaca tcctctttgt catcaaccgt
    36121 acccttgcca tcggtgggga caactctagc aacgacggtg tcctagaaaa tgcccttatc
    36181 gctgaaacac ctgctgctaa aaatggtaag attatccaac taacaccaga cctctggtat
    36241 ctaagcggag gcggacttga atcaacaaaa ctcatgattg aagacataca aaaagctttg
    36301 aaataagcca cttcaaactc aatttaatac tcaatgaaaa tcaaagagca aactaggaaa
    36361 ctagccgcag gttgctcaaa acactgtttt gaggttgcag atgaaagctg acgcggtttg
    36421 aagagatttt cgaagagtat aaaattttga cattctaaaa cgcatcctat caagtttact
    36481 caaacctgat aggatgcgtt tttatcattt tgaaatctat ttaccccacc tcattcccct
    36541 tcttgatttc gtttaaggga aaagtggtct ggaacgggat ccttacctgt tttcgaccag
    36601 ggatgacaac gtaaaatccg agccaagccc atcaataccc ccttaaaacc atgtttttca
    36661 atagcctgaa tcatgtagtt ggaacaagtc agctcaaagc gacaagaggg tggaaagact
    36721 ggtgagataa aacgttggta aaagcgcaca ggcgctatta aaattcgttt cattatttct
    36781 tagttacagc catggtgtgt agttggctga tttctttttt attaagacga cgggattctc
    36841 ctggacggag tcctgtcaag tctaggtgtc cgaaacgagt ccgagacaac ttatctactt
    36901 ggagaccaac agcttcaaac atctttttaa cctgatggtt acgcccttca tggatggtca
    36961 actgcaccac agagcgattt ttgactgggt ccactttgag aatttcataa acagctggct
    37021 tggttttctt accatcaatc tcaagaccac gggtcaaggg gcggagattg tccttattgg
    37081 ccacaccttt aacacgcgcg acataaacct tgtcaatctc attacgaggg tgaatcatct
    37141 cgtctgtaaa gtccccatca ttggtcaaaa tcaagacacc tgatgtatcc cagtccaaac
    37201 gacccacagg gtaaatacgc tctttgacat tgggcaagag gtcgacaacc gtcttgcgac
    37261 ccttatcatc tgtcacactg gaaatcacac cgcgtggttt gttaagcaga tagtagacct
    37321 tttcttcgtt gtagataggt tgaccttcaa cttcgacctt gtcgcctgac ttgatagtgg
    37381 ttgctagttc acgcaccact tggccgttaa ccgtcaccaa gccttgctta atcagctctt
    37441 ctgcttttct cctactggcc acacctgcgt gggcaatata cttattgatt ctcatcttct
    37501 tctatccttt caccaaataa ttggctttct tgggcttgaa tctcaagctc atcaatcact
    37561 ggtaattctt ctaaatggtt tatccccatg taatctagga aataatccgt agtcacatag
    37621 aggttggggc gccccaatac ttcctttttc ccgtcttcct ttatcaggtc aaaagcctgc
    37681 aactttgcca aggctccact cgagttaact ccacggatgg catcaatttc tatccgcgta
    37741 atcggctgtt tgtaggcaat aatggacaag gtctcaaggg cagcccgaga caagctctgg
    37801 ttgataggcg ccttagagta ttccttcaaa atctctgcaa attgaggctt ggtcaccaat
    37861 ctataagcac cacttgtctc aatcaaagcc aaactggaat ctgggtcctt ttcatacttc
    37921 tgggctaatt ttcctaaact ttgctggatg cctgtcggtg gcagagagag gagttcagct
    37981 aactggcgga cccgaatccc atcttcaccc gctacaaaca agagcgcttc tatttttgct
    38041 aaagtactca tctttcctct ctatcaagtc tagctttgag gcacttgact ttcttccttc
    38101 ttttccatga gatagatatc tccaaaactc tcctcttgca cgaggatcaa ctcctgggtt
    38161 ttgattaact ctagggttgc caaaaagagg gtgatgacct cttggacatt ctgggcttcc
    38221 ttgaacaaat cctgcaagcg caattgagct cgtccaacca aggactcttt cacgataatc
    38281 atcatgtcct caatcttata ctcatcccgc aagatcgtcg tgtgattttg tgcaaactcc
    38341 tcttttttct tggctaggat atttgaaaaa gccaaaaaga ggtcaatggt cgtcttgtca
    38401 tgcacaagct ccgcatcttc gtaaatcaac tctgtcggcg ctttggaata atactgggcc
    38461 cgttcttggt gcttggcttc caagtgctca cccaagagct tgaacttgcg atattcttcg
    38521 atttgagaga ggaggtcctg ctccaggtca ttccccaagt ctgtcacttc tgctaccttc
    38581 ggaaggagtt tacgactctt aatcagcatg agctgactag ccatgaccat gtactcaccc
    38641 gtcacttcca gacgcatggc ctgcagggtt gagacatagg ctagatactg ttcgatgact
    38701 tccgtaatgg gcacatcgta gatatccatc tggtacttag aaaccagatg caagagcaag
    38761 tccaggggtc cttcaaaatc ttttaattta atatccatta tctatatttt tctaaggtca
    38821 ggactgtttt taatcctaat ttttttgcaa tttcgtacaa atcgaccttg ttttctattt
    38881 gtcttagaat aaactgttca cgtaagactt gagctgataa ggatggaaaa cctttctcct
    38941 tgacaaaaga ttctaactga cgaaaggccc actgacgaga atagggtttc tctcctcttt
    39001 caaaaagata ggtctgcccc atcaagggtt ccaattctga aagcaaggcc gtgggaatgg
    39061 tgacaattct ctgttgggaa gccttgctga ttcgcaacac ctgaaaatcc agattgatgt
    39121 ccgcaacctt gatggctaaa atctcactgg gcaagagccc catttctagg attaagagcg
    39181 ctagcaagcg gccctctgga tggtcgcttt cctgccaaaa agagtctagg tatagaatct
    39241 ctggcttttc cgtcttcttt tcagcttgtt tggctaattc caagcggtaa aagctgtcca
    39301 cctctccttt ttgatagaga aagtatagaa attggttaca ggccgaaatc tttcgcttct
    39361 gggcgctgat ttttagattg gctagctggg cttggtaaat cttgagactg gtctcagaaa
    39421 tccgctcacc taccatgtct aaaaattgct ccaaatcata cttataggac tgcttggaat
    39481 tgacagacaa gccctgcttt tcctctaaaa aggctgaaat cctgtctctc attggcatcg
    39541 aatctcatat tccttactaa agtcatgcaa gagggcatta acggccttga ggatggactt
    39601 gcgcgtaata atcccttgga aaataccctc tgcatccaca accggtaaga aggactcatc
    39661 tactagcttg tgcaagacct ccgtaatggt gaaatcaggc gaaacaaccg ctacgtccgt
    39721 ttttgtcata tgaacgatat ccgtatccgc catgatttct tggctcaagt catgctccat
    39781 ctgataagcc ataatatctc tgagtccaat cgtcccaaca aactgttttt catctgtcac
    39841 aacgggaaca cgggtatagg tcatctgact gagcaagagg gtcgcatgat ccgcattgtg
    39901 ggtatcaatc aacacagcta gatttttagc aggggtcaaa aaagtttcct cctgccccaa
    39961 caagaaagtc tcaaactcct tggcaatcat cggctaaact ccttggacaa acctggatac
    40021 acctcgtgat ctcgtgtcaa aaagtccact ttgaagtaac tatcatcaat ctccacacga
    40081 gcatagagac attctctgat ggtacctcgt ggttgactga tagaacctgg atttagaaag
    40141 aggatcttgc cttccatcca agcacttggc acatgcaagt gaccatagag gcagatagcg
    40201 gcctcttcct cctgagccca gtagtccaac ttttgaaagt tgaaattgat gtcaaacaag
    40261 tgaccatgag tttggataat cttggtcgaa ccaagctcag tcaccagacg ttctgggtag
    40321 ccggcgtaga agtccatgtt ccctttaaca acgcggatgc cctcccaaag tggagaatac
    40381 ggacgtagtt cagaatcgcc gttatgaaaa acggcatcga ctttgcccac atagcgatca
    40441 cggacttctt ccacaatcaa gctatcgcca tgggaatcgc tcattacaat gatagtttgc
    40501 tttgccatga tggaaatacc tccaaaagtt tcttaacggc taaggcacgg tgagattgac
    40561 tatttttttc ttccagggtt aattcagctg atgactcacc tgtctctcct acaaggaaga
    40621 ggggatcata gccaaagcca ttttcaccct taggttcaaa gttaatataa cctgaccagt
    40681 ctgcttcaac aactaaactt tccttatttg ggctggctac gactagggtt gtgtggaact
    40741 gagccgagcg gtccttgagt tcaaagacca tggccaattc gtgcaagagt ttggcattat
    40801 tttcacggtc agttgctccc acacctgcga aacgagctga ccagacgcct ggtaagccac
    40861 caaggacatc gactttgaga ccagaatcat ctgccaaaac catcttgccc gttaattgag
    40921 aaatggtttc tgccttaagg cgggcatttt cttcaaaggt catacctgtt tctgctactt
    40981 caggcaggtc agggtagtca ttaagatttt ccacatcgta gcctaactta tcaaagatag
    41041 ctcggaattc cttggtttta ccttcgttac gagtcgcaat caacaaggtt tctctgacct
    41101 tgcttgtctc aaagaaatca tgaacattga ccccttcttt aggcaattct acatacaaga
    41161 gttgcccatt ttcaaccaag agcagggccc catgacgttg aataacttcc aagtttcgtc
    41221 ccatttcttg attaagcatg tctaccacaa aggagaacaa acggtaggta gaaccatagc
    41281 gtaaaacagt aactgaaagc gggaaaccat actcttcatc tccaaatatt ttggagaatt
    41341 caaacagagg aaaatctgtc ttatagtcgc tcaaactgtt aacgccacca aaaatactat
    41401 aagacccaac ataccagtcc tggtcatcct tatattcata aattttattt gtcataattc
    41461 tacatgctcc acatgaatct ctttttccag ccattcttca ccaatttgtg caaaactttg
    41521 gctactggct gttgtgtaaa aacggtgatg gagtggtcca gcatcgcgac cacgattgat
    41581 ttcaaaataa ttgagtaaga ctgagatatc ccgtacgcac tctgccccac tatcgatgag
    41641 ctgaaccttt ggccccatca cattttggat aatagggcga aggagtggat aatgagtaca
    41701 gcccaaaatc aggctatcca cctttccaac caagggacgc agggtttcat agaccacctt
    41761 cttggtaaca ctggttgaca gggcacctga ctcaaccaag ggagcaaact tgggacaggc
    41821 caagctctcc acctgtaagt cgggatccag atcatggatt ttctgacggt atatgtctga
    41881 ttgtaccgtc atgggcgttc caatcactcc gattttccca ccttgactgg acttgatggc
    41941 tgccgaagct cctggcaaaa ttacacccaa gacaggaata tctagttgag ccttgatttc
    42001 ttcccagacg accgcagtcg cagtgttaca agcaatgaca atcattttga catccttggt
    42061 caagagaaag ttgaccagct gccaagtata ttcacgaatt tgctcagcag gacgggggcc
    42121 atagggcgcc cgcgccgaat ctccaatata gacgatttct tcatggggaa gctggcgcat
    42181 gagctcgcgc acaacggtca agcccccgac acccgaatcc aaaaaaccaa ttggtcgatt
    42241 atccatacag tcttctttct agtctttttt ctgattgatc gttcattatg attccttgta
    42301 ctgaacgaac tgaccgacag cttgatagaa tgtcaactac ctctctctta atcataatca
    42361 aatatcaata gaatgcaagg aaaaagtctc atccctaaac cataaccaac atagtgagaa
    42421 gtctggaact ttcatcccag acttttcctt atttattttt tctttttatt gttagcaagg
    42481 gctgcctttt gttggcggat gatttggtgg taaacttgtt gtaccttagc ttcgcttggt
    42541 ttttgaccat ttgcactcaa aagagtacga actgcttcag cattcaaacg tgggttgtca
    42601 gcaaattctt tttcgatttg cttacgaacc aagtacattc ctccaagagc tcctcctaga
    42661 aaagctagca caatcaatac aattgctaaa agtaaatcca tcatttttct cctgtttctt
    42721 tttgaatccc tttcattata ccacaaacta gccaccctga ccagtttgtt ctacactttc
    42781 agggatggaa tagacagcaa aaagaaccct gcttttctga aaaagaggtc tccttgctaa
    42841 gtttatactc aatgaaaatc aaagagcaaa ctaggaagct agccacaggt tgctcaaagc
    42901 accgctttga ggttgcagat aaaactgaca cggtttgaag agattttcga agagtattaa
    42961 tttacataaa tagccagtgt ttgatagggt ttgagtagaa ttttctcaga cacttctgca
    43021 tcttcatagt ttgatatcaa aatctgtcca ttttggtaga ctgctggcaa gtcgatttcc
    43081 acttctttag cataaaagtt attgagcact agtaactttt gatcctcaaa ctgacgttca
    43141 aaagcgtaga cttgtttgct atcttcaaag gctggtttgt aacttccttc tgaaatgatt
    43201 ggcatttcct tacgcagtcg aatcaagtct tgatagaagg taaaaatcgg accctggatt
    43261 tcattttcta cattgatatc tttataggat ttaccagctt tcaaccatgg agtgcctgtt
    43321 gaaaatcctg cattttccga agcatcccac tgcatgggaa tgcgtgaatt atcacgcgac
    43381 ttagcttgaa taatctggaa ggcttcttgc tgactctttc cttcttctaa gagcatctga
    43441 taggcattaa gcgattcgac atccacataa tcagccatag aatcatagtc tgggtcaatc
    43501 atcccgattt cctcacccat gtagatataa ggtgtcccac gtgacaggtg aatgctggct
    43561 gctagcatgg tggctccttc cttgcggaag ttttgaatat cgacaaaacg gttcaaggca
    43621 cgtggttgat cgtgattgtt ccaaaagagg gcactccaac cgtctttatc actcatttcc
    43681 ttaccccaac tatggtaaag actcttcaac tcttcaaaat caaagggagc caaggtccac
    43741 ttttgtccat ccttatagtc caccttgagg tgatgaaaat taaaggtcat ggataattcc
    43801 tgacgatcag gcgacgaata gaggacacag ttttccatgg tggtagaaga catttcccca
    43861 actgtcataa agctatcgtc agatccaaaa gtggcttggt tcatcatacg caaatagtta
    43921 tgaacgatgg gtttgtctgt ataagctggc ttcccttcat tttcaggaca gtccactgaa
    43981 acctcgtcct taccgatcaa attgatcaca tcaaatcgaa aacctttgac acccttgtcg
    44041 cgccagaaat taacaacctt gaaaagctcc ttacggacat tgggattgcg ccagttaagg
    44101 tcagcctggg tctcatcaaa taggtgaaga tagtatttcc cagtatcccc gaaaggcgcc
    44161 catgcagaac caccaaactt agactgccaa tctgttggtt ggtcttggat gaagaaaaag
    44221 tcttgataat acttatcacc agctagggct ttctgaaacc attcatgctc tgtcgaacaa
    44281 tgattaagta ccatgtccag cataaagtca atcttgtgct ctttaccgac acacaccatt
    44341 tcctcaaaat cagccatatc accaaaaaga ggatccactg ccatataatc tgaaatatcg
    44401 taaccattat cccgttgagg gcttggatag aatggattga gccagaccat atccacacct
    44461 agtttggcta aatagggaat tttttcgata atcccacgga aatccccaat accgttttca
    44521 gtggtgtctt tgtaagattt tggatagatt tgatagacta cttttccttt atcaagtgtc
    44581 atctgtttct ccttttctga taaaagggag gaagcagtct tccgtcccta tttgtgctat
    44641 ttcaattata ctcaatgaaa atcaaagaac aaactaggaa gctagccaca ggttgctcaa
    44701 aacactattt tgaggttgca gatagagctg acgtggtttg aagagatttt cgaagagtat
    44761 tagattcgtg tagcgaccat gagagatgct ccagcttgga tcgttgtcgg ataagttcca
    44821 gtaatagtcg ctgtataagc atcttggttg gtgatgataa caggagtttc tgtcaccaga
    44881 cctgcagcct taatgacatc catatcaaaa cgaatcagtt gctggccaac tataacgtga
    44941 tctccttgga ctacaagact ttcaaaacct ttgccatcaa gacctactgt atccataccg
    45001 atgtggatga gcaattcaac tccctcgtca gagacaatgc cgatggcatg cttggtaggg
    45061 aaaagaaccg tcactgttcc attaactgga gaggtcaact caccttggct tggttcaatg
    45121 accagacctt gccccatgac acctgatgca aaaacaggat ccgtcgcttg actcaattct
    45181 ttcacttggc cagttagtgg gctgataatt tctaccgaag taagttctac tggttcatgg
    45241 ctcacaaatt ctgcttcttc ttgagcaacg aattctgcct gcaagttcgt atcgccctct
    45301 atttttgtga agagaccagc cttgcgaaag aagaaagtca agagcattgg aacaacaatc
    45361 gcaactagca tagttcctgc aaatggcagc atgtattgag gttgaataga gagaatacct
    45421 ggcaaaccac cgataccaat agaagccgca gttacattaa aagtaacgga taacatgcct
    45481 gcaagggctg agccagtcat cccagcaaca aatggataaa tatattttac gttaacccca
    45541 aaaagagctg gttctgtaac accgagatag gctgaaatgg ttgcaggaag tgaaacctga
    45601 gcctcacgct catcatggcg atgcatgaaa taataggcaa acacggctga gccttgagca
    45661 atattagaaa gagcaatcat tggccatagg gcagtgccac cagcatccgc aatcaattgt
    45721 gtatcaatgg cattggtcat atggtgcaga cctgtgatga caaatggagc gtagagggca
    45781 ccaaaaattg caccgaagag ccatttaact ggaccagtta aacctgccaa gacaactgat
    45841 gaaagtcctt gtccaattgt ccaaccgatt ggtcccaaaa cagtatgagc caaaatcaag
    45901 gctggaatca atgacaaaaa aggtacaaaa atcatggaaa tgacttctgg gatatgtttg
    45961 cgccagaaaa tttcaagata agacagactc aaacctgcaa gcaaggctgg gataacttgg
    46021 gcttggtaac caatacgatt aacagtaaaa taaccaaaat tccaaaccca gtttgccgcg
    46081 atatcagctg ctggcgttga agcaaccgca taggcattga gcaactgagg cgataccaaa
    46141 cagattccga gaacaatccc caaaatttgg ctggttccca tcttacgaga aacagaccaa
    46201 gtaatcccta ctggtaagaa ctggaagata gcttcaccag gcaaccagag gaagtgatta
    46261 acccctgccc aaaactgaga ggattctgtg atggtcttgc catccaacat cgaccaatgg
    46321 acaccttcca agacattacg gaaaccgagg atcaatccac caacaatcaa ggctggaata
    46381 atcggagtaa agatttccgc cagagtggtc ataacacctt gaaccacgtt ttgattactc
    46441 ttagctgcag acttggttgc ttctttggaa acaccctcaa tacctgaaac ggctgtaaaa
    46501 tcattataaa agatgggcac gtcatttcca atgattacct gaaattgacc tgcatttgta
    46561 aaagttcctt taacagctgg aattgactcg atagctttaa cattagcctt cttatcatct
    46621 cttaaaacaa agcgcatccg tgtcgcacag tgagttacgg cagtcacatt ttctttgcct
    46681 ccaattgcct gaagcagatc tttggcttct tgttcaaatt ttcccatttg attctcctta
    46741 tacttgtcaa agcaagtttg atttgataag tatattgtaa acgataccaa acttgtctac
    46801 aacttgtttg gtataaaaag ggtgtttttt tgtaaatttt ctagcacttg tatggtaaaa
    46861 tagatacagg tgttcattaa actagactaa aaacctattt aagcaggcaa aatgaagaaa
    46921 taccaacaat tatttaagca aatccaagaa accattcaaa acgagactta cgctgtcgga
    46981 gatttccttc ctagcgagca cgaccttatg gagcaatatc aagtgagtcg tgataccgtc
    47041 cgaaaggccc tgtctctcct ccaagaggaa ggattgatca aaaagataag agggcaaggt
    47101 tctcaagtcg tcaaagaaga aaccgtcaat ttccctgtat ccaacctaac cagctaccaa
    47161 gaactagtta aagaacttgg actgcgctct aaaaccaacg tggtcagtct ggacaagatt
    47221 attattgata aaaaatcctc actgataacc ggtttcccag agtttcggat ggtttggaag
    47281 gtggtccgcc agcgtgtggt ggatgatctg gtatccgttc tggatacaga ctatctggat
    47341 atggaactaa ttccaaatct cactcgccaa attgctgagc agtctatcta ttcttatata
    47401 gaaaatggcc tcaaactcct tattgattat gctcagaagg aaatcaccat tgaccactca
    47461 agcgaccgag acaagattct catggacatt ggcaaagacc cttatgtcgt ttcgattaaa
    47521 tcaaaagtct atctccaaga cggacgccaa tttcagttta ccgaaagtcg ccataagtta
    47581 gaaaaattta gatttgtaga ttttgcaaaa cgcaagaaat aaaagactga gacaccagat
    47641 ctcagccttt ttctttatcc caaaactaat tcatcactga ccagactttg gccactattt
    47701 ttctggaaga gatgcataag gtcttcaact gtcagatgct ttttctcttc tcccttgaca
    47761 tctaccacta tctttccttg atagagcata atgagacgat tgccgtactc aatcgcatga
    47821 ttcatatcat gggtaatcat caaagtcgtc cactgatggt gctccacaat cttttgcgtc
    47881 aagttcatca ccatttgact ggttttcagg tcaagtgccg cagtatgttc atccaaaagt
    47941 aaaagtttgg gtttcaccag agctgccatg actagggtca aagcctgtct ttgtcctcct
    48001 gagagatatt gagtatctac ttttaagcgg ttttcaagac caatattcaa ctccttcaag
    48061 gcctcttgga actggattct atccttctcc ttcacacccc aaccaagccc tctcttttgc
    48121 tcacatctca aggcaatagc catattctcc tcaatcgtca aacgagaagc tgttcccatc
    48181 ttaggatctt gaaaaacacg ggcgatatca ttggctctct ttcttacatt cagatgttta
    48241 atggatttcc ctgccaataa aaggtccccc tcgtccaccg atagattgcc agccaagata
    48301 ttcatcaaag tggatttccc tgctccattt ccacaaatca cagagataaa atctccctct
    48361 tcaacctcta aatctaatcc tttgaggaca tggttctcat tgaccgtccc tgcttcaaat
    48421 gtcttgtgaa tattttcaag tgttaacaaa cttgccataa ctttctcctc ctattcattt
    48481 ctcaatttca gaccacgaat ctttaatctc ttttgcaatt ctggtgcaaa taaaaccaaa
    48541 gcgagcaaga ttgcattaaa gagacgtacc aagttttgat ctagatttgg aatttcatag
    48601 atatttaaaa taatcaaacg gtaaacaata gcaccgattc cgatggataa taagcggcct
    48661 ccaatggtca agtcgtgtat caagacttcc gagctcaaac caacaacaat ggttcctgtc
    48721 ccagaagtca catctgaaaa tccatcattt tgggcaaaca aggaaccaca tagggcaatc
    48781 aaaccgtttg aaatcatgta accaacaatc ttcatggtgt ttacattgac tccattggcc
    48841 tcactcatcg ggatattgtc cccagtcgaa cgcaagacca aaccaatctc tgttttcatc
    48901 aaaagggtca agaccaaaca agtaagagac agactaaact aagtgagaaa acagctcctt
    48961 catttgtcag acccaagctc gccaactgtt taaagacggt tgcagaatct cccaaggaaa
    49021 gattgggtac actgcccata attttaatat tgattgaata gagccctgtc aaggtcacaa
    49081 tccctgtcaa gagagctggg attttcatat tggtgtggag cattcctgat acaagacctg
    49141 ctaccatacc tgccaccaaa gcaagtaaag tcgcaagcca aggatttgcc cctgcctgta
    49201 tctgtgatac aacgactgct gcccccagag gaaaggctcc ctcagcagtc atatccgcaa
    49261 tatccaaaat acggaaagtc aagtagaccc caattgccat aatcgaccac aacaaacctt
    49321 ctgataaact agataacaca aaattcatct taatcctcct tattccttgc cttctaactt
    49381 actaatatca attcccaatg catctgccat ttcttgattg gtatgcaatt ccagtttttc
    49441 aggcaactca actgctatat tttctggttc ctcacctttt aaaacacgaa tcagcatgcg
    49501 agctgtctgt cttcccaatt cttcataatt ggttccgtag ttatacaagc caccaacagc
    49561 aatcatttct gttgaaccac cgaatactgg aaccttgtgt ttaatagaaa cctgcttaac
    49621 tgtttccatg gttgacgaaa tgatattatc agttgggaca aaaaccatat ccacctctgc
    49681 catcaaactc tctgctgccg ccttgacgtt attactgtcc aagattgttt tttcaacaac
    49741 ggtaaagcct ttttctttca gaagtcgctt agcttcatcc ttttaagcaa ccgaattggg
    49801 ctcgctctga gtatagagga ttccaatcgt tttagccttt agcaacactt tctttatcaa
    49861 attgatttgg gttgaaatgg catctgatga ctgatcgctt gtcccagtta cattgccccc
    49921 aggatgttct cttgactcaa ccaacttggc actgactggg tctgttacag ctgaaaagat
    49981 aactggtgtc gtttgcgtcg tattggccaa gctctgagca gaaggccttg cgatggctag
    50041 aacgacatcg ctggattctg ctagttgctg ggaaatcgtt tttagatttc tttgttctcc
    50101 ctgtgcattt tgcaaatcaa tctcaatatt ttccccctca acatagcctt gtttggccag
    50161 ctcatccaca aatccttctc tagtagcgta taaggactgg tgggtaataa attgcgaaat
    50221 accgatacga aagacatctt tttcttatct gccttcaact gatgcaaact gatcagagaa
    50281 gtcaagagga gccccactac caagaggggg ctagtgattt tcgaacaact ttcataatga
    50341 aactccttct cagaaaagat aaaacaaaaa accgcctaga tactatctaa acggatactt
    50401 gaaataacct aacaagttac aacttagcta gtccatttag atattcatct atatggacca
    50461 caatcaaaaa tcttagccac atagatacaa acaaattgct tgaactgttt gcatccatgg
    50521 tgacatgtct acaaacacta tctaaagtag ctaaagtaaa agttttgatt catagttacg
    50581 gcttgtctct tattcatttc tttttctgct ttcttttttg atgcttccta tcctaccacc
    50641 tttttcatca cctgtcaata atatttcaga attttttaaa atttttcgaa aattctttca
    50701 ggaagctttc aaagtttttc aaatcagtcc aacaaaaaaa gttttataat ttccataaaa
    50761 attgacatgg aaattataaa accattacta gtttagtcct ttttgataac gtgccaattc
    50821 ggcttggttc gcccaaacat agtgacctgg acggatttct accatagatg gcttatcagt
    50881 ctcatagtcg tgttgacttg gatcgtaaac cttcaagacc ttcttacgtt ccaagattgg
    50941 atctgggatt ggtaccgctg aaagcaaggc ttgagtatat gggtgaattg gattgttaaa
    51001 caattcttct gtttctgcaa cctctacaat aacacccttg taaataactg cgatacgatc
    51061 tgaaataaag cgaacaaccg acaagtcatg ggcgatgaag agataggtca ggccgagctc
    51121 tttttggaat tttttgagca agttcaagac ttgggcacgt acagaaacgt ccaaggctga
    51181 aattggctca tctgcaataa caaagtctgg ttgcatgacc aaggcacggg caataccgat
    51241 acgttgacgt tgaccgcctg agaattcatg agggtaacga gtcaagtgct cagcaagaag
    51301 acctacttca cggataatat tttgaacttt ctctttacgt tcttcttcat ccttaaataa
    51361 acggtgattg taaagacctt cagaaataat ataatcaaca gtcgcacgtt cattcaaact
    51421 tgcggcaggg tcttggaaaa tcatctggat tcgacgaatc aattccgcag cttgttcacg
    51481 cgatttctta ccattaatct tttgaccatc aaaaatgata tctccattac ttgtatcatt
    51541 tagaccgatg atagcacgac caatagttgt tttcccacta ccggactcac ctacaagcga
    51601 gaaagtttct cccttgttga taaagaagtt agcattttta accgcgacaa acttcttact
    51661 tccttcaccg aaggaaattt ctaaatcttt gatttctact aatttttcag acatttcctt
    51721 cctcctagtc agccagatgg gcaaatccca ttttttcacg gatcttatca tggagatttg
    51781 caatcacagc tggtttttct acttttggag catcctcatg aagaagccaa gttttagccc
    51841 aatgtgtctc tgatactgag aattgaggag ctttttgttc gaagtcaatc tgcattgcgt
    51901 agtcagaacg caaggcaaaa gcatcccctt tcaggtcagt ataaagtgac ggaggtgttc
    51961 ctgggattga gtaaagatcc cctttatcat cagcaagctg aggcaagcta gacaagagac
    52021 tccatgtata tggatggcga gggtcataga agacttcctc aaccgttcca tactcaacga
    52081 tttctcctgc atacataacc gctaccttat ccgcaatact tgccaccaca ccaaggtcgt
    52141 gggtaataaa gattgttgtg aaatgatact cgttttgtaa agattttagc aaatcaataa
    52201 tctgagcttg aatagttaca tccaaggcag ttgttggctc atcacagatc aagacatcag
    52261 gtcggcaggc aagggcaatc gcaataacga tacgttgacg cattcctcca gaatattgga
    52321 atgggtattc attaaaacgt ctatctgcgt ctggaatgcc aaccttattc atgtagtcaa
    52381 tggccaattc tttcgcttct ttagctgttt ttccttggtg ttttacaata acttctgtaa
    52441 tctgactacc aattgtttta atggggtcca aactagtcat tgggtcctgg aagatagtcg
    52501 caatcttagc accacgaatt tgttcccaat ccttgtgaga agataaagct gtcaagtcct
    52561 gaccacggta gtcaatacta ccttgggcaa tacgaccatt ttcttcgagc atacctgtga
    52621 aggtctttgt caaaacagat ttacctgatc ctgactcacc taccaaggct aatacttctc
    52681 cttcgactag ttcaagggaa acgccgcgaa tggctgtcaa tactttgtca cgaacgtcaa
    52741 attccacgac aatatcgcga gcagtcaaaa ttacattttt ttcttttgtc atttctactc
    52801 ctatctatgt gtacgtggat cactagcatc cgctaagttt tgaccaacta cgaaaaggga
    52861 caaggatacc aagacaaggg ttgtcaatgg aatccagaac aagtaagcat tggttgttac
    52921 gttttgtgaa taatccgaaa tcaaacgacc caaacttggc actgtaatcg gtaatccaag
    52981 accgaagaaa gacaagaagg cttcgtatga gataaagctt ggaagcattt gagtcatggt
    53041 tgtcacaata acagatacca attgaggcat gatatttttg gcaacaatct tcaaggttgg
    53101 tgttcccaaa gtacgtgacg ccaagttgta ttccaagtca cgatagcgca agatttgcac
    53161 acggatcatg aaggcaatac caatccatgt tgttacgctc atggcaaaaa tcagattcca
    53221 gaatccagct ccgattgagt aagtcaagac aataacaatc aaaagaggtg ggatgtttga
    53281 gatgacgttg taaacttcca tcatgacacg gtcaactgat tttgaaatac cccaaatacc
    53341 accgacaaaa acaccgataa ccaagttaat cactgtcgca atcacagaaa tgaggatgga
    53401 gttacgagct ccgaaccaga caccgtcaaa gagcgattta ccgttactgt cagtaccgaa
    53461 ccaatgctcc gcatttggct tgatataacg aacactaaag tcgtttacct tgctgacatc
    53521 attgaaatca aacttagaaa acattgggta gatgaaactt atcaaaatga tggctaccaa
    53581 gattcccaac atgactacag ttgatttttt cttcataaat tgtttaaaca ctgatttcca
    53641 gtaagaatat gctggcgcat caatagtttc agaggcaaaa tcgtcacgtt ttacaaactg
    53701 aaatttttct ttatcgattg tagacattat ttgcctcctt tctcagtcaa tttaatacgt
    53761 gggtcaataa tagtcatcca aatatctccc aaaagacgtg agaagataga aatacatgta
    53821 aagatgaaga caagaccaac gaccatagag ttattagatg cttttacaga gtcaatcaac
    53881 attttaccca tacctgggaa ggcgaagact gtttcagtaa gggttgcacc accgataacc
    53941 ccaataatgg caccaggaat tcctgaaacc agcggaacca tggcattttt aaagatgtgt
    54001 ttgtttgaaa tttctttttc agacaaacct tttgcacgag cgaaacgaac aaagtcttga
    54061 gattgcaagt caatcatgta acgacgaatc caaatggctg taacaggagc acccaacaaa
    54121 ccaaggatga ctgctggtaa aacgtaagaa cgccaatctc cagctcccaa gatagggaat
    54181 gaatctggaa gggcaataga tgatccaatc aatcgaacaa tgtaaaccaa ggcaatcgtt
    54241 ggaagagcaa gcaagaaggt caaagtccct gttgagaggc tatcaatcca agtgttcttg
    54301 aaacgagcca tggctgaacc aagtggcacg gcaagagcat aggcaagaac caaaccaatc
    54361 aaaccagtaa tagcagagct gacaatcata gatggatatt ggtaattact ttcagtcgct
    54421 gtataaggat catctttccc atagctagct acttcacgag agtcagcctg actaggtgac
    54481 ttgtaggttc ttgagtaaat atttacagaa gacgttttct tacctgttgg gaactgaact
    54541 tgggcagttt tggtttgtcc ttgaccttga gtaataacct gaagaactgg tgtattagca
    54601 taggttgggt aagagtcacc taaattcaag ttcacaaagt tttgatgaac aaatgggaac
    54661 tgactgttaa agtacaagag atatttatgt ttagttcctg aaccgaccaa tgaccatccg
    54721 atagctggat cattttcaaa acgaaggtag cgtttcaagt ctggattttc agggtcttgg
    54781 attttatttg tatggtcaat gtcaatcaag ttagcataga agtgaaaaac acgttcaaaa
    54841 attggaattt cacgagtagc atagaattga ccactttcag taaattctcc caaagtccaa
    54901 ccatgaccta attgattgat gtacttttca taaatagctt tattggtcgc atttgcttct
    54961 actgttacag aagaatccat gctacttgcc ttttcttgca actctttagt atcgtaatac
    55021 tcaatgtagc ccatacgctc aaacacagta ttttcatagt tatcacgttt atcagccgtt
    55081 gtcgcaattt tattatagtt aggatcctgc ttgaaaatca attttcgagg aaccaaggta
    55141 tagataatcg tgtaggtcaa agtcgttact aagaaaatcg aaaccaatga ccgcaaaaca
    55201 cgcataaaaa tatatttttt catattattt cctttaaaaa tcccaaaaga accttctcct
    55261 catggagaga aagttctatt agaaattatt tacttcacat gacttgccaa ttctttttga
    55321 gctttctcat ttgattcagc tttttctttc aaccattttt cacgagcttt ttcatactct
    55381 tccttagtca ccactttatc ttgtaatttc aaatatttga agtaaacatc tgacccctta
    55441 gagcctgttt gcgcagaagc tccagtaaat ggaacaattc gtgaaagcac tggtgctgca
    55501 ccagaagaag ccatagcagg aataaagagt gaactatctg tcaaccatgc ttgagccgct
    55561 gcatattttt cataacggac attcaagtcg cttgtctctt tggcagcttc atcaactaat
    55621 ttatcgtatt ctttcaaacc aacttgaact actgaagggc tatttggatt atcaaatcct
    55681 aaatatgttt ttgtagtttc actgctagtt gtttttaaaa tatccaggta agtagatggg
    55741 tcttgatagt ctggccccca tgaaactcct cccgatacat cccaatcctc agatgaagca
    55801 ttggcagcat agtaagtaat attaaggaat tcatcacttg tcatttgttg aatatcaaca
    55861 acgacatttt caacaccaag aactgtttct acagattgtt taaaggactg aatacgagat
    55921 atgtagtttt ttgatgcttg gtctactgga acgtccagat gaataggaaa ctgaacgccg
    55981 tctgcttcta aagctttctt agctttcgca aactctgcct tggccttgtc agcattgaat
    56041 aaaccatcct gcccatcagc taaattcaca cctttccact catcaccata agcaggaagt
    56101 tgagcagcga ctaaatcacc aaaggtcttc tcaccagctg aaacaaagtc tggttttaca
    56161 aataaattac gaactgctaa agctgctcca tctttaccat tgatttgagc tgagtaagct
    56221 gagcgatcaa gagcaaaatt caaggcttga cggaaatctt tgttaagcaa tgccttctta
    56281 gtagctactt tctctgaatc tgtagtttta gaagtatagt tgtaactttg gcgatcaata
    56341 ttcacaccca gaccagcaat cccagagcct gattgtgtgt aatagatatt gtccttgtat
    56401 tcttctgcaa ccttagaata gttggagctg gtagggtaaa gacgggcata actataagct
    56461 ccactagtga agttacgctc tagcgactcc tgatctgatc catcatagta agctagattg
    56521 atagtatcta ggtggacatt ttctttatcc caatattgct cattttttac aaactctaca
    56581 gaagattttg cagtcaaccc tttcaacaag aatggaccat tataaagcaa ggatgtcgga
    56641 tctgttggtt tagcaaaatc gcttcctttt gatgtttcga attcttcatt cagaggccag
    56701 aaaatagaat aggtcaactt agagttccag aacggttcag gctggttcaa agtgtattgt
    56761 aacgtataat catcaaccgc cttgacacca actgttgaaa aatctgttga agttcctgat
    56821 agataatctg ccaagccttt aaccgaattt tcagctaaat acatagcttc tgatttttta
    56881 tctgctgcgt gttttaaacc gttcacgaaa tctttagccg tcacctctgc atattcttct
    56941 ccatcagagg taaaccattt aaccccttta cgaatcttat aagtgtaggt caaaccatcc
    57001 ttagagactt cccaatcctc tgcaactgca ggagcaagat taccgtaatt atcgttagtg
    57061 aataaaccat caatcccatt tgaagtcact actgttgtac tatttttact tgaaatcagg
    57121 tagtccaagg tttctgggtc tgctgtataa acatagccat aagctttagg ggctgatgaa
    57181 tcagatgatt ttgaagaact gcatgctgca agtacacctg ctgctaataa aacaagacct
    57241 gctgtagcaa atacacgatt ttttttcatt ttctactcct ctgtttatgt gaattataga
    57301 ttgacaacca ttatatcaca ttatccatta aaaatcaaac aaattttcag aatatttagg
    57361 cttgttggca caaatttttc attttttttg aatatatgat tcaaattgtc gttcgaagtg
    57421 tcaaagacta cagtgaaaat aggaaatttg acgcagaaac tttggagttt aggaagacat
    57481 acagtaaaat gaaatacgga cggaacaatg tgattttgga attcaaatta aattataaca
    57541 atattgtaga agtatcattc tagtattcaa gattcagttt actatgtctt ttcacaccaa
    57601 ccttattccg aattcaatta cttttgtgat ttacatatat agattaagac tatcttttat
    57661 actttaaaat ttctcgctac cttatccact atatgctcct cgctatcacg tttctattca
    57721 tagcctacga tttcactatt gctttctctg acaattctta tttcctgcgt cagacttaaa
    57781 acgatctatc cccagaccat tttaatccgc tacctcacga cagtcaggct tggggagcgc
    57841 tattgtattc accggtagtg gatccctaca gaggacttac acctcagatg cacgacatgc
    57901 ccatagtata aaaaaatctc ctacccaagg tagaagattt caaacttata aaacttaatc
    57961 cgtcatgtcc gataccaaca ttcgatgctc caatggaata ctgcacataa ctagcaagaa
    58021 aataaagcct gactgaatcc agaagagagc caagtcaaaa attccgtgca cagcaaccac
    58081 tgtaaggaaa gatagataaa ggccgataat cggacgtttc cccgactcct gactcatatc
    58141 catcatcaag cgaacaggag caacagaaga caaaactaat aaaatggtac ccacaattcc
    58201 gtaactcaga atcgtatcaa tataaagact gtgggcatgt tcatgataag gagcatgtat
    58261 ccgaggataa gagtgcatat aggtcaatgg cccttcaccc caaaaaggat tttgcttaaa
    58321 caaggccatc ccagcatccc agatagaaat gcgttcttcc atagaagagt ctaaagtacc
    58381 cattcgaact cccaaatcac tagaaaagag gaaactcaaa ccaatcgcga agaccccaat
    58441 actaagccaa aaggccttcc agtttttaat agtcgtaaag agatagataa ttgctccagc
    58501 gataatagca ggaaaggcag ttcgattttg agtaaagttc aaaccaaaga gattaacaaa
    58561 gcctgcaatc acacagaata ctttcaacca attcaacttg gtcgttgtaa acagatagaa
    58621 agcaatcata atacagaaac aacaaataat tccataataa ttaggattaa agaaggtcac
    58681 ttctgcccgg ttctgatgcc acacctgcat attgggtgaa agaaaagcat agttaaattt
    58741 cttcacaatt tggaaatgtt ctaaactggc aaaagcagct gacaagacac taccaaacaa
    58801 gacgaactgc aaaatcaatc gaaagaattt atgggataaa atcgactgat agtgcaaaaa
    58861 gaaaatagta aatagaaaca ttcctactga agccacaaga cccatccaat tttgtgcaag
    58921 aatggatata acagtactat agctaagaaa aagaagcagc atcggatgct cccccatttt
    58981 ctgaagaata cttttcatgt ctcctgtaaa aatcaaactg ataatatata aacagagtac
    59041 aactacaaaa agataaaagg gtaaaaagat acttaggata attcccaata aaatcagctc
    59101 tttactagac aaccccttca gcttttcaat aaagcctatt gatttcaaaa tgaatccttt
    59161 ctctccaaat cagctgattc agataatagt aagctatcct atattgtacc acttttttag
    59221 caatttgaaa acaaaggaaa cgttttccaa aataaaaacc ctattttatc caccatatca
    59281 aggcttcaaa atgatacttc aactccattc tcaattaccc gataagtctg attttgcaaa
    59341 tcaatttcta ctactgctgt tacggactta tctttatttt gacgtttgat tacaatgctg
    59401 tgagctgttg gtgtctctat ctcagtagtc ccttctagat caaaggcttc tgaacggtta
    59461 cggaaagaaa atagattgag aagggccttc acaacaggtc gttgcacttc ttttgctatt
    59521 tcctcgttgc tatagtaatg acgattaata tttcgacctt ctttagtttc ttctaataat
    59581 ttcaagtcat tcttgcctgc taatagaccc acatagtaaa cctgaggaat acctggggca
    59641 aaagcttgaa ttagacgagc gagaaaatac ttgacatcat catctccaag cgctgaatag
    59701 taggttgaat tgatttggta gatatctaag ttgttatact cggcactaga gtacttacgt
    59761 ttgacattag ctccaacctt atagagttca tttgaagcat agtcaatctc ctcatcggtc
    59821 aggatatcct tgacatctac tactccaatc ccatcatggg tatctagcgt cgtaaattgc
    59881 ttcatcgggc tcatcttcag ccacttagcc aaacgctctg ttctggaact gtaaagagta
    59941 taaagtgtca ccattggaag agtaaaatca taaacatagt aatcatggtc tgctatttta
    60001 aactgaatcg aatagtgttc atgaatctca ggtaaaagct ctgtcccata ctcagcagcg
    60061 atatctcgaa ctttgtccaa taaatcccaa atatctggtt ccacaaagaa atcattagta
    60121 tccaatttct tcactgcata agcaaaggca tctagacgaa tcaaatcaca cccattactt
    60181 gccaagtgct gaatggtctt acggataaat tccatagtta cttctttggt cacatcaaga
    60241 tcaatctgct cctcaccaaa ggtattccac aaatgttcca ctgaaccatc ttcaaacaca
    60301 atctcttgct ttggtgcacg atccttacgc ttgtaaatta aatctacatc agactgtgtc
    60361 ggacggtttt ctggccaaaa cttatcccag tttaaaaaga gatctttaaa ttcactggct
    60421 tcatgttttt cttgatagtc cttataatac ttggattgac gagaaatatg attaatcata
    60481 aaatcaaaca taagataata tctctcacct aaacgcttaa catcctccca atcaccaaaa
    60541 gctgagtcca cttcgtcgta gtcaactggc gcaaatccac gatcacctgt tgatgggaaa
    60601 aatggtaaaa ggtgaactcc tccaatagca tctccaaaat gctcttccaa attatcatat
    60661 aagtctttaa gattatttcc aaggctatca gaataggtaa tcaacatggt tttattttga
    60721 attggcatca ttactctcct ttttctaatt gaagccaagt ctcatatgat ctggcttcat
    60781 aaataaaatt cattttaaat ctctatttat catcaaactc gtactaatat agactgtgat
    60841 aaacaaagta ctactttctt gttttctaca tagaattatc aacaagctga actcttcctc
    60901 tgtgtcaaag actatagatt ccatgagctc ttcttatact attcgaaaat ctcttcaaac
    60961 cacgtcagct tcaccttacc gtactcaagt acagcctgcg gctagcttcc tagtttgctc
    61021 tttgattttc attgagtatt acttcactgc cccgttgctc attcctgaaa tgatatggca
    61081 ttggaagaag agatagacaa tggtgatact gataatgccg accacgtaag aggcaaagct
    61141 tggtccgtag tcgttgaaat attggcctgc gtagttgtat tggaacaaag gcagagtcca
    61201 cattttggaa tcccggttca agacaaggag tggcaacatg aagtcattcc agaaccaaag
    61261 ggcattgatg atcatggttg tcgcatgcat cggtttcatc attgggaaga tgatgcggaa
    61321 ataggttgta aattgattag ccccatcgat ctctgctgct tcatccagac tttctggaat
    61381 cgagattttg atatagccaa catagagaaa gagggtctgt ggaatcgcat aggtcaagta
    61441 gagcaagatc aaaccaaagg tattagccaa accgagttta ctcatcataa ccgtaatcgg
    61501 aatcatgatg acttggaaag gtacgaagat tccgaggatt aagagggtat acatgatggt
    61561 aaaggctttt cttttactca tattgcgagc gatggagtag gctgccatag ggataaagat
    61621 cattactgca agtaaagaca agacagtgat gacgacagag ttccaataat agcctccaat
    61681 cccatcagct aagagacggc taaagttgtc ccatgtgaag ttggttggaa agccaaataa
    61741 attatctaca atatccttag tgggtttgaa ggaactaaag agggtagcaa ggagcggcac
    61801 taaaatcaga accgatccta gaatcaatag aatgtatttg ccaatcaggg cttttctttc
    61861 atcttgtttc atcatgcttc tcctcttaaa tttcaaattt cttagatact ctcaattgga
    61921 tgatcgaaat cactacaatt aagaagaaca agattacggc aatggcattg gcataaccga
    61981 attggttgtt tttaaaggca tagttataaa ccaagagccc aagtgaggtt gtggcattgt
    62041 ttggaccacc accggtcatg gcaaagactt ggtcaaaggc agtcagccca ccttttaggg
    62101 ctaggataaa gaccatagag acacttggta gcaagtaagg caattcaatg ttccagaaaa
    62161 cttgcttgct cgtcgcacca tcaatccttg ctgcctctgt aatctcagtt ggaatagatt
    62221 gcaaaccagc taggaagatg atgatgggca tagccacccc ttgccaaaga aggacaaaga
    62281 cagccgcaaa gattgctccc cacttagtcc ctaaaagact ggtttggaga aattcaatat
    62341 gaagggcatt cccaatcgct ggaagaccgt agttgaagac ttgcttgaag atcaaagcca
    62401 ctgtcaaacc agataaaaca gctgggaaga agaaccaagc acggaagaag gtttggcctt
    62461 tgattttaga attcaagaca cgcgcaatga agatcccgag tgcaatctca ccaaccacca
    62521 tggcaatcgt aatgattgcg gtaaagccaa tcgcattcat gaattttgga tccatgaaga
    62581 ggagcttaaa gttgtttaag ccgacaaatt tgtagttata agtcaatcct gtccagttgg
    62641 taaaactgta aaaggctcct tgaaacatcg gcacatagaa gaaaattgct tgtaacaaga
    62701 gggggatgac cacaaaagcc catgcccaat atttttgtaa tacttttttc atagtctctc
    62761 tactcctaat ccacatccgc tttcatcggg ttaaagaagg cattcaaatc attgaccatg
    62821 ccttgtttat caccggtcaa gacatagttc atggtcaagg tatggaagtc tgcttcactg
    62881 gtccagtatt gttgcaacca gaccaagtga cgatccgtaa aggcatattc ggtcatacca
    62941 gcaagcggtg aatcttctcc tgcttgtttg accccttcga tcgctgttgg agatccgtcc
    63001 acatcgtagt atttttgcat gacttctgga cgggtcatat attccacaaa ggcattggct
    63061 tcttttggat gtttggtggt ggctgagata gaccatgcca agtctcccgc accaacggtt
    63121 aagctttgtc ctttttcttt tcctggaatc atgaaggtcc caatcttaaa gttcggtttt
    63181 tgttcattaa tcgctgtgat cgcccaagac ccatttggtg tcatgaggac atccccacgt
    63241 gcgaaggctc cgataacatc gatatagcca gcaccttccc agttcttttg cttagagcca
    63301 ttgatgcgaa ggatgtccat gaccttgata tcatctttca taatcggatc cgacaattta
    63361 atggcatttg gttgagaata acgaaggtat tgatttgctt cttttcctcc acctgttgct
    63421 gtcgcaaagg ctaattgatt gtaaccattg agtgtccaag catctgcacc tgcaattcca
    63481 aatggtgttt gtcctttagc aacgatatct ttgactaact gttcaaattc atcccaggtt
    63541 tcaggaacct tcaagcccag ttcttcgaat ttatctttgt tgtagtaaat tccataagca
    63601 ttagctgtaa aaggaacgtt gtaaactttt tcgtttacag catatttttc agcgtagcca
    63661 tttttcacgc gtttcaggta gtctttgttg ctcaaatctt caaaaacacc tgcttttgcc
    63721 cattcttgca gttcgatgga ctgtgggtaa atattgacca catcaggcac atctcctgcg
    63781 agaacgcgtg tcttcaatac ttcaccagca tttggtacat tgacgacttt gaccttgatc
    63841 ttagggtttt ccttctcaaa atcacgagtg atttcttcca aggttttggt catttctttt
    63901 ttctggttga aatactcgat ggtcactgtg ccatccgcag atttaccata gttggagcaa
    63961 gcgccgagcc caaccaaagc taaacctgta gttgcaagaa gtccgatttt tttataccat
    64021 tccattagaa agcctccttt ataaatttat acacccttat catagtcttc taaaaatata
    64081 ctgtctactc aaaaaatctc cttgggataa gataacagtt aggcccgcat acattagttc
    64141 tgcacctgag taaatttcgc cattttcctg taatttatat agtccctctt catccaaatc
    64201 ttttaatttt aaagttgttt ccatggtctc tacaacagat aaaacgcgaa cgtaggttac
    64261 aatcgtttga ttttcgtaat taaattgtac agctgcttca ttggatacag tatcaggatt
    64321 aattagtcta tactgctgtc ctaactgaac tactggtcgt aattctttat acaagttcac
    64381 ctgattagca atcgtagctt tctcttcatc tgataaattt gtcaaatcaa gttcatagcc
    64441 caaatttccc atcattgcta caaggccacg tgtttctaat ggtgtcattc gtcccatctg
    64501 atgattcggt actgctgaca catgagcccc catagaaatg gttggataga gataggatga
    64561 accgtattga attggtaaac gtgcaatggc atcagtatta tcactagccc aaacttgtgg
    64621 gaaatagcgc atcataccaa gatcatttcg tccaccacca ccagagcagg actcaaagag
    64681 aatatggctg tgcttctctg tcagataaga aacgagttcg taaagcccca gcatgtactg
    64741 atgagattgc atctgtgtct ctagataagt taatccattc cctagcttag tgatattgcg
    64801 gttcatatcc catttaatgt aatcaatatc atgataagat aggagttgat ctaagacact
    64861 tttcaagtat tctactacct gaggattggc aagattaagt actaattgat tccgagaata
    64921 agtatgctca tagtcaggaa cctgaatagc ccagtcagga tgtcgacgat acaaatcact
    64981 atctacagaa atcatttcgg gttctaacca aagtccaaac tgcaaacctc tttcatggat
    65041 agctgaaatc agactttcta gacttccacc cagtttttcc tcattaacaa cccaatcacc
    65101 taaagcacga ttatcatcaa aacgattgcc aaaccaacca tcatctaata caaaaagttc
    65161 aatgccaact ttcttagctt catctgctaa ctctaacagt ttttctatct gaaagtcaaa
    65221 gtaagtagct tcccagttat tgattagaat tggacgttct tttttagaaa attcacttag
    65281 cataatgtgc ttcagtacaa aattctgact ttcatgacta ataccagtta atccctgatc
    65341 tgaatgggtc actaaagcta ccggtgtttc aaagtattcc tcaggagcta acttacaaga
    65401 aaagttttct ggattaatgc caatagccac ccgaacttca ttcaattgat ttttttgaac
    65461 aaaagcttca aagttgccac tatacattag ttgaatagca aacacattcc cagcatcctc
    65521 tgtgactcct tgttcgcata gtaaaagagc tggtgtttga gcatgaccag aagcacctcg
    65581 gtttgagcta atcgaaaaga ttccttgttc tacctgttga cgtctaacag tcttttcacg
    65641 agcataagca ccctgcagag ttactatttc gtaatctgca gctggaaaat cagccataaa
    65701 agaaaaatct ttatggatga caacttcctg attactatta ttatctaatt tactgtagct
    65761 agcaatagtc gcatcattat taaaagtagt ataatacaaa gtcagactaa gttgagcctt
    65821 agaatcttct aacattaaga caagagtctc tgtatcgtcc atgctatgtg gagaaggtaa
    65881 gccctgtgga ccattctgac cttttaaaat ctttgcttct acaaatcgaa agtctgttac
    65941 ttcagttaca ctatgctgaa cctgtatggt tggtttccta aaatctccta agccatgttg
    66001 tccaaaaatc tgtcgctgag tatctaaact aaaggttcga ttagtagccg ttggatttcc
    66061 tgaaaaggca tggtctcgtt cataaacact attggaacct ttatagttct taatagtctt
    66121 tcctaaatgt ttcaaaagta agtagccatt tcgattttca ataatcaaac ttagattttt
    66181 actctcaaca taaaatagat tattctctat cctaactccc atttacttca cctcatcact
    66241 ttattgatta tattttatca cctgaaatcg ctttccaaaa tagaaaaatg tctcaagaat
    66301 atggtaaaat gttaggtagg aggtagcaca tgctagtttt ttcagaatac cagactggaa
    66361 caattgacct tgccctaagc ttttatggat atgaggaatg cacacctaat tactcttttg
    66421 gtccagccat tcgtgataca tacgtcctac attacattac taaaggacaa ggaaaatttc
    66481 attacaaggg taaaattgtt gatttaaaag aaggagattt ctttctatta aaaccagagg
    66541 aactaacctt ttatcaagca gatagtaaag aaccttgggc ctactactgg ttaggaatca
    66601 ctggagggaa atcccctgat tattttgctc tttctcaaat ttctgatcaa tcctatctca
    66661 tccaatctga aacttgtcat acccagacta ctgcaaaact catctcagac attgtccgct
    66721 tcgctcagat tacaaaatca agtgaattat ctcaactcca tatcatggga caacttcatg
    66781 aactgatgtt tcatctggga actattgctc ccaatcagaa aaaaaagaat atttcatcaa
    66841 cccaccaact ctatcttgaa tgcaaacgat taattgatag ccactatcct caatcactta
    66901 caattcaaga tttagcaaaa gaactatccg ttcacagaag ctacttatca agcgtattca
    66961 aagaatttaa taccttatca cccaaagaat acctactcta cattcgaatg caccgagcta
    67021 gacaacttct cgaaaatacc caagagtcca tcaaggtaat tgcatactcg gtaggttttt
    67081 cagatccact ccatttttcg aaagcttata aacaatactt taatcagact ccaagtcata
    67141 caagaaaaga atactctcaa taccaactag tgagaaaggc aacattatga aatcctacca
    67201 agctgtctac caaatcctat ctaaagaaac cgactatatc agcggagaaa aaatcgcaga
    67261 aaaactatcc ctaagccgaa catcaatttg gaaagccatc aagcgactag aacaagaagg
    67321 cattgaaatt gatagtatca aaaatagagg atataaattg atgaatggtg accttattct
    67381 tccagagatt ctagaagaaa atcttccaat taaagtcagc tttaaacccg aaacaaaatc
    67441 aacacaacta gatgcaaaag aagcaattga tttaggccat gaagcaaata ccctctatct
    67501 agcttcctat caaacagcag gccgaggccg ttttcaacgt tccttctact caccacaagg
    67561 tggtatttat atgacactcc atcttaaacc aaatctcccc tatgacaaat taccatccta
    67621 cacactactt gtagctggag ctgtctacaa agctattaag aacctaactt taatagatgt
    67681 cgacataaaa tgggtcaatg atatctatct aaacaatcat aaaattggag gaatccttac
    67741 tgaagcaatg acctctgtag aaactggctt agtcacagat atcattattg gagtaggtat
    67801 caatttcact attaaagact tccctcagga attaaaagaa aaagctgcca gcttatttaa
    67861 agctacagct cctataacaa ggaatgaatt gatcatagaa atctggcgtg ctttcttcga
    67921 aacaccagca gaagagctat tatacctata caaaaaacag tcattcattc taggaaaaga
    67981 agtcactttc acactagagc aaaaagacta caagggactt gctaaagaca tctcagaaaa
    68041 tggaaaactt ttaattcaat gtgataacgg aaaagaaatc tggctaaata gtggcgaaat
    68101 ttctctcaat agttggaagt aaaataacac aattataata taaacgatat aaaaataact
    68161 tcagattagt aattcaatta agttttacgg atctgaagtt ttattgtctc taaaaacaaa
    68221 aaagagagtt acaaactctc attaaaacgg agaataaggg attcgaaccc ttgcgccagt
    68281 tacccgacct aacgatttag caaaccgtcc tcttcagcct cttgagtaat tctccaatta
    68341 atgggcacga gtggactcga accaccgacc tcacgcttat caggcgtgcg ctctaaccac
    68401 ctgagctacg cgccca
//
LOCUS       DBEJAU010000005        51977 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC323 isolate 683620
            SAMN38261939-rid24807223.denovo.005, whole genome shotgun sequence.
ACCESSION   DBEJAU010000005 DBEJAU010000000
VERSION     DBEJAU010000005.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261939
            Sequence Read Archive: SRR26833919
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 51977)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 51977)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576303.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576303.1
            Genome Coverage       :: 154x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/19/2025 01:05:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,121
            CDSs (total)                      :: 2,078
            Genes (coding)                    :: 1,943
            CDSs (with protein)               :: 1,943
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 36
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 72 of 135
            Pseudo Genes (incomplete)         :: 63 of 135
            Pseudo Genes (internal stop)      :: 51 of 135
            Pseudo Genes (multiple problems)  :: 46 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..51977
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261939-rid24807223.denovo.005"
                     /strain="GPSC323"
                     /isolate="683620"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            complement(224..586)
                     /locus_tag="ACL29Z_000382"
     CDS             complement(224..586)
                     /locus_tag="ACL29Z_000382"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000895063.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein-export chaperone SecB"
                     /protein_id="HGR0068747.1"
                     /translation="MLEVGLNSLINLFTFTFDILYPIVKVGHADDYSHGAVKLSVSLV
                     DKDAMKKISVTVIGYFEINIDENITDILYVNGTAILYPYLRSIVSTVSAIDSSEAMLL
                     PTINVLELLDKSQPFEEE"
     gene            600..746
                     /locus_tag="ACL29Z_000383"
     CDS             600..746
                     /locus_tag="ACL29Z_000383"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0068748.1"
                     /translation="MKTKEQTRKLAVGCSKHCFEVVDRTDEVSNHTHGKATLTWFEEI
                     FEEY"
     gene            complement(856..1014)
                     /locus_tag="ACL29Z_000384"
                     /pseudo
     CDS             complement(856..1014)
                     /locus_tag="ACL29Z_000384"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000040325.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="group II intron reverse transcriptase/maturase"
     gene            complement(1392..2081)
                     /gene="rplA"
                     /locus_tag="ACL29Z_000385"
     CDS             complement(1392..2081)
                     /gene="rplA"
                     /locus_tag="ACL29Z_000385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006145049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015934 - large ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L1"
                     /protein_id="HGR0068749.1"
                     /translation="MAKKSKQLRAALEKIDSTKAYSVEEAVALAKETNFAKFDATVEV
                     AYNLNIDVKKADQQIRGAMVLPNGTGKTSRVLVFARGAKAEEAKAAGADFVGEDDLVA
                     KINDGWLDFDVVIATPDMMALVGRLGRVLGPRNLMPNPKTGTVTMDVAKAVEESKGGK
                     ITYRADRAGNVQAIIGKVSFEAEKLVENFKAFNETIQKAKPATAKGTYVTNLTITTTQ
                     GVGIKVDVNSL"
     gene            complement(2289..2714)
                     /gene="rplK"
                     /locus_tag="ACL29Z_000386"
     CDS             complement(2289..2714)
                     /gene="rplK"
                     /locus_tag="ACL29Z_000386"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004226069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L11"
                     /protein_id="HGR0068750.1"
                     /translation="MAKKVEKLVKLQIPAGKATPAPPVGPALGQAGINIMGFTKEFNA
                     RTADQAGMIIPVVISVYEDKSFTFVTKTPPAAVLLKKAAGVEKGSGTPNKTKVATVTR
                     AQVQEIAETKMPDLNAANVESAMRMIEGTARSMGFTVVD"
     gene            complement(3023..3739)
                     /gene="ldcB"
                     /locus_tag="ACL29Z_000387"
     CDS             complement(3023..3739)
                     /gene="ldcB"
                     /locus_tag="ACL29Z_000387"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000747760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LD-carboxypeptidase LdcB/DacB"
                     /protein_id="HGR0068751.1"
                     /translation="MKKRYLVLTALLALSLAACSQEKAKNEDGTAKTEQTAKADGTVG
                     SKSQGAAQKKAEVVNKGDYYSIQGKYDEIIVANKHYPLSKDYNPGENPTAKAELVKLI
                     KAMQEAGFPISDHYSGFRSYETQTKLYQDYVNQDGKAAADRYSARPGYSEHQTGLAFD
                     VIGTDGDLVTEEKAAQWLLDHAADYGFVVRYLKGKEKETGYMAEEWHLRYVGKEAKEI
                     AASGLSLEEYYGFEGGDYVD"
     gene            complement(3742..4212)
                     /locus_tag="ACL29Z_000388"
     CDS             complement(3742..4212)
                     /locus_tag="ACL29Z_000388"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HIT family protein"
                     /protein_id="HGR0068752.1"
                     /translation="MCLICQRIDLIKKEENPYFVKELETGYLVIGDHQYFAGYSLFLA
                     KEHVTELHHLKKETRLRFLEEMSLVQEAVAKAFAAEKMNIELLGNGDAHLHWHLFPRR
                     TGDMNGHGLKGRGPVWWVPFEEMTAETCQVKPEEIKRLVECLSSEVDKLLEIKE"
     gene            complement(4214..5251)
                     /locus_tag="ACL29Z_000389"
     CDS             complement(4214..5251)
                     /locus_tag="ACL29Z_000389"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001077203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M42 family metallopeptidase"
                     /protein_id="HGR0068753.1"
                     /translation="MNQTVEYIKELTAIASPTGFTREISNYLVKTLEGFGYQPVRTAK
                     GGVNVTIKGQNDEQHRYVTAHVDTLGAIVRAVKPDGRLKLDRIGGFPWNMIEGENCTV
                     HVASTGEKVSGTILIHQTSCHVYKDAGTAERTQDNMEVRLDVKVSNEKETRALGIEVG
                     DFISFDPRTVVTDTGFIKSRHLDDKVSAAILLNLLRIYMEEKIELPVTTHFAFSVFEE
                     VGHGANSNIPAQVVEYLAVDMGAMGDDQQTDEYTVSICVKDASGPYHYDFRQHLVTLA
                     KNQDIPFKLDIYPFYGSDASAAMSAGAEVKHALLGAGIESSHSYERTHIDSVVATERM
                     VDAYLKSGLVD"
     gene            complement(5349..6674)
                     /gene="brnQ"
                     /locus_tag="ACL29Z_000390"
     CDS             complement(5349..6674)
                     /gene="brnQ"
                     /locus_tag="ACL29Z_000390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006152071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015658 - branched-chain amino acid
                     transmembrane transporter activity [Evidence IEA];
                     GO_process: GO:0015803 - branched-chain amino acid
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid transport system II
                     carrier protein"
                     /protein_id="HGR0068754.1"
                     /translation="MAKKGTLTGLLLFGIFFGAGNLIFPPSLGALSGEHFLPAIAGFV
                     FSGVGIAVLTLIIGTLNPKGYIYEISTKIAPWFATLYLSVLYLSIGPFFATPRTATTA
                     YEVGISPLLSDANKGLGLIVFTVLYFAAAYLISLNPSKILDRIGRILTPVFAILIVIL
                     VVLGAIKYGGTSPQAASAAYQASAFGTGFLEGYNTLDALASVAFSVIAVQTLKQLGFS
                     SKKEYISTIWVVGIVVALAFSALYIGLGFLGNHFPVPAEAMKGGTPGVYILSQATQEI
                     FGSTAQLFLAAMVTVTCFTTTVGLIVSTAEFFNERFPQISYKVYATAFTLIGFAIANL
                     GLDAIIKYSIPVLVILYPITIAIVMIVIVNKFVALSKPGMQLTIAVVTVIAIASVLGS
                     SFKVEFLANLVSVLPFAKASLPWLVPAIVGILLSLVLPNKQESDVFEME"
     gene            complement(6845..7132)
                     /locus_tag="ACL29Z_000391"
                     /pseudo
     CDS             complement(6845..7132)
                     /locus_tag="ACL29Z_000391"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000658232.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
     gene            complement(7292..7870)
                     /locus_tag="ACL29Z_000392"
     CDS             complement(7292..7870)
                     /locus_tag="ACL29Z_000392"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520460.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil-DNA glycosylase family protein"
                     /protein_id="HGR0068755.1"
                     /translation="MSQIERIKQAIMADSQNASYTERGIEPLFAAPKTARINIIGQAP
                     GLKTQEAGLYWKDKSGDRLRDWLGVDEDTFYNSGYFAVLPMDFYFPGHGKSGDLPPRT
                     GFAEKWHPQLLQELPDIQLTLLIGQYAQAYYLQEKISGKVTERVKHYKDYLPAYFPLV
                     HPSPRNQIWMAKNPWFEAEVVPDLKKRIKTIL"
     gene            complement(7924..9324)
                     /gene="pepV"
                     /locus_tag="ACL29Z_000393"
     CDS             complement(7924..9324)
                     /gene="pepV"
                     /locus_tag="ACL29Z_000393"
                     /EC_number="3.4.13.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000125034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004151 - dihydroorotase activity
                     [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0006221 - pyrimidine nucleotide
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dipeptidase PepV"
                     /protein_id="HGR0068756.1"
                     /translation="MTAIDFTAEVEKRKEDLLADLFSLLEINSERDDSKADAQHPFGP
                     GPVKALEKFLEIADRDGYPTKNVDNYAGHFEFGDGEEVLGIFAHMDVVPAGSGWDTDP
                     YTPTIKDGRLYARGASDDKGPTTACYYGLKIIKELGLPTSKKVRFIVGTDEESGWADM
                     DYYFEHVGLAKPDFGFSPDAEFPIINGEKGNITEYLHFAGENTGAARLHSFTGGLREN
                     MVPESATAVVSGDLADLQAKLDAFVAEHKLRGELQEEAGKYKVTIIGKSAHGAMPASG
                     VNGATYLALFLSQFGFAGPAKDYLDIAGKILLNDHEGENLKIAHVDEKMGALSMNAGV
                     FRFDETSADNTIALNIRYPKGTSPEQIKSILENLPVVSVSLSEHGHTPHYVPMEDPLV
                     QTLLNIYEKQTGLKGHEQVIGGGTFGRLLERGVAYGAMFPDSIDTMHQANEFIALDDL
                     FRAAAIYAEAIYELIK"
     gene            complement(9337..9942)
                     /locus_tag="ACL29Z_000394"
     CDS             complement(9337..9942)
                     /locus_tag="ACL29Z_000394"
                     /EC_number="1.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002924506.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA];
                     GO_function: GO:0016657 - obsolete oxidoreductase
                     activity, acting on NAD(P)H, nitrogenous group as acceptor
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase family protein"
                     /protein_id="HGR0068757.1"
                     /translation="MKFLELNKKRHATKHFTDKPVDPKDVRTAIEIATLAPSAHNSQP
                     WKFVVVREKNAELAKLAYGSNFEQVSSAPVTIALFTDTDLAKRARKIARVGGANNFSE
                     EQLQYFMKNLPAEFARYNEQQVSDYLALNAGLVAMNLVLALTDQGIGSNIILGFDKSK
                     VNEVLEIEDRFRPELLITVGYTDDKLEPSYRLPVDEIIEKR"
     gene            10113..10913
                     /locus_tag="ACL29Z_000395"
     CDS             10113..10913
                     /locus_tag="ACL29Z_000395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000714621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter substrate-binding
                     protein"
                     /protein_id="HGR0068758.1"
                     /translation="MKKFSLLLAILPFLVACGNQATPKESSSQKTIVLATAGDVPPFD
                     YEDKGNLTGFDIEVLKAVDEKLSDYEIQFQRTAWESIFPGLDSGHYQAAANNLSYTKE
                     RAEKYLYSLPISNNPLVLVSNKKNPLTYLDQIAGKTTQEDTGTSNAQFINNWNQKHTD
                     NPATIDFSGEDIGKRILDLANGEFDFLVFDKVSVQKIIKDRGLDLSVVDLPSTDSPSN
                     YIVFSSDQKEFKEKFDKALKELYQDGTLEKLSNTYLGGSYLPDQSQLQ"
     gene            complement(11095..11928)
                     /locus_tag="ACL29Z_000396"
     CDS             complement(11095..11928)
                     /locus_tag="ACL29Z_000396"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001015777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase family protein"
                     /protein_id="HGR0068759.1"
                     /translation="MNHKIAILSDVHGNATALEAVIADAKNQGASEYWLLGDIFLPGP
                     GANDLVALLKDLPITASVRGNWDDRVLEALDGQYGLEDPQEVQLLRMTQYLMERMDPA
                     TIVWLRSLPLLEKKEIDGLRFSISHNLPDKNYGGDLLVENDTEKFDQLLDAETDVAVY
                     GHVHKQLLRYGSQGQQIINPGSIGMPYFNWEALKNHRAQYAVIEVEDGELLNIQFRKV
                     AYDYEAELELAKSKGLPFIEMYEELRRDDNYQGHNLELLASLIEKHGYVEDVKNFFDF
                     L"
     gene            complement(11918..13762)
                     /gene="uvrC"
                     /locus_tag="ACL29Z_000397"
     CDS             complement(11918..13762)
                     /gene="uvrC"
                     /locus_tag="ACL29Z_000397"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001061148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009380 - excinuclease repair complex
                     [Evidence IEA];
                     GO_function: GO:0009381 - excinuclease ABC activity
                     [Evidence IEA];
                     GO_process: GO:0006289 - nucleotide-excision repair
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrC"
                     /protein_id="HGR0068760.1"
                     /translation="MNNLIKSKLELLPTSPGCYIHKDKNGTIIYVGKAKNLRNRVRSY
                     FRGSHDTKTEALVSEIVDFEFIVTESNIEALLLEINLIKENKPKYNIMLKDDKSYPFI
                     KITNERYPRLIITRQVKKDGGLYFGPYPDVGAANEIKRLLDRIFPFRKCTNPPSKVCF
                     YYHIGQCMAHTICKKDEAYFKSMAQEVSDFLKGQDDKIIDDLKSKMAVAAQSMEFERA
                     AEYRDLIQAIGTLRTKQRVMAKDLQNRDVFGYYVDKGWMCVQVFFVRQGKLIERDVNL
                     FPYFNDPDEDFLTYVGQFYQEKSHLVPNEVLIPQDIDEEAVKALVDSKILKPQRGEKK
                     QLVNLAIKNARVSLEQKFNLLEKSVEKTQGAIENLGRLLQIPTPVRIESFDNSNIMGT
                     SPVSAMVVFVNGKPSKKDYRKYKIKTVVGPDDYASMREVIRRRYGRVQREALTPPDLI
                     VIDGGQGQVNIAKQVIQEELGLDIPIAGLQKNDKHQTHELLFGDPLEVVDLSRNSQEF
                     FLLQRIQDEVHRFAITFHRQLRSKNSFSSQLDGIDGLGPKRKQNLMRHFKSLTKIKEA
                     SVDEIVEVGVPRVVAEAVQRKLNPQGEALLQVAEERVDYQTEGNHNEP"
     gene            complement(13802..14503)
                     /locus_tag="ACL29Z_000398"
     CDS             complement(13802..14503)
                     /locus_tag="ACL29Z_000398"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001267193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M57 family metalloprotease"
                     /protein_id="HGR0068761.1"
                     /translation="MRWLFRLIGAFFSFVWRLFWRLVWIVVLLCVLAFGLLWYLNGDF
                     QGALKQAERSVKIGQQSIDQWEKTGQLPKLSQTDSHQHSEGRWAQASARIYLDPQMDS
                     RFQEAYLEAIQNWNQTGAFNFELVTESSKADITATEMNDGGTPVAGEAESQTNLLTGQ
                     FLSVTVRLNHYYLSNPYYGYSYERLVHTAEHELGHAIGLDHTDEKSVMQPAGSFYGIQ
                     EEDVANLRKIYETSE"
     gene            complement(14582..15814)
                     /gene="murN"
                     /locus_tag="ACL29Z_000399"
     CDS             complement(14582..15814)
                     /gene="murN"
                     /locus_tag="ACL29Z_000399"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001229509.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan bridge formation alanyltransferase
                     MurN"
                     /protein_id="HGR0068762.1"
                     /translation="MALTTLTKEEFQTYSDQVSSRSFMQSVQMGDLLEKRGARIVYLA
                     LKQEGEIQVAALVYSLPMLGGLHMELNSGPIYTQQDALPVFYAELKEYAKQNGVLELL
                     VKPYETYQTFDSQGNSIDAEKKSIIQGLTDLGYQFDGLTTGYPGGEPDWLYYKDLTEL
                     TEKSLLKSFSKKGKPLVKKAETFGIRLKKLKREELSIFKNITKETSERREYSDKSLEY
                     YEHFYDTFGEQAEFLIASLNFSDYMSKLQGEQSKLEENLDKLRLDLSKNPHSEKKQNQ
                     LREYSSQFETFEVRKAEARDLIEKYGEEDIVLAGSLFVYMPQETTYLFSGSYTEFNKF
                     YAPALLQKYVMLESIKRGIPKYNFLGIQGIFDGSDGVLRFKQNFNGYIVRKAGTFRYH
                     PSPLKYKAIQLLKKIVGR"
     gene            complement(15819..17039)
                     /gene="murM"
                     /locus_tag="ACL29Z_000400"
     CDS             complement(15819..17039)
                     /gene="murM"
                     /locus_tag="ACL29Z_000400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001819885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan bridge formation alanyltransferase
                     MurM"
                     /protein_id="HGR0068763.1"
                     /translation="MYRYQIGIPTLEYDQFVKEHELANVLQSSAWEEVKSNWQHEKFG
                     VYREEKLLATASILIRTLPLGYKMFYIPRGPILDYGDKELLNFVIQSIKSYARSKRAV
                     FVTFDPSICLSQSLINQEKTEFPENLAIIDSLQQMGVRWSGKTEEMGDTIQPRIQAKI
                     YKENFEEDKLSKSTKQAIRTARNKELEIQYGGLELLDSFSELMKKTEKRKEIHLRNEA
                     YYKKLLDNFKDKAYITLATLDVSKRSQELEEQLAKNRALEETFTESTRISKVEAQKKE
                     KERLLEELTFLQEYIDVGQARVPLAATLSLEFGTTSVNIYAGMDDDFKRYNAPILTWY
                     ETARYAFERGMVWQNLGGVENSLNGGLYHFKEKFNPTIEEYLGEFTMPTHPLYPLLRL
                     ALDFRKTLRKKHRK"
     gene            complement(17151..17930)
                     /locus_tag="ACL29Z_000401"
     CDS             complement(17151..17930)
                     /locus_tag="ACL29Z_000401"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000290006.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HGR0068764.1"
                     /translation="MAVMKIEYYSQVLDMEWGVNVLYPDANRVEEPECEDIPVLYLLH
                     GMSGNHNSWLKRTNVERLLRGTNLIVVMPNTSNGWYTDTQYGFDYYTALAEELPQVLK
                     RFFPNMTSKREKTFIAGLSMGGYGCFKLALATNRFSHAASFSGALSFQNFSPESQNLG
                     SPAYWRGVFGEIKDWTTSPYSLESLAKKSDKKTKLWAWCGEQDFLYEANNLAVKNLKK
                     LGFDVTYSHSAGTHEWYYWEKQLEVFLTTLPIDFKLEERLT"
     gene            complement(17999..19660)
                     /locus_tag="ACL29Z_000402"
     CDS             complement(17999..19660)
                     /locus_tag="ACL29Z_000402"
                     /EC_number="3.1.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0004540 - RNA nuclease activity [Evidence
                     IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease J"
                     /protein_id="HGR0068765.1"
                     /translation="MSNISLTTLGGVRENGKNMYIAEIGESIFVLNVGLKYPENEQLG
                     VDVVIPNMDYLFENSDRIAGVFLTHGHADAIGALPYLLAEAKVPVFGSELTIELAKLF
                     VKGNDAVKKFNDFHVIDENTEIDFGGTVVSFFPTTYSVPESLGIVLKTSEGSIVYTGD
                     FKFDQTASESYATDFARLAEIGRDGVLALLSDSANADSNIQVASESEVRDEITQTIAD
                     WEGRIIVAAVSSNLSRIQQIFDAADKTGRRIVLTGFDIENIVRTAIRLKKLSLANEIL
                     LIKPKDMSRFEDHELIILETGRMGEPINGLRKMSIGRHRYVEIKDGDLVYIATAPSIA
                     KEAFVARVENMIYQAGGVVKLITQSLHVSGHGNVRDLQLMINLLQPKYLFPVQGEYRE
                     LDAHAKAAMAVGMLPEHIFIPKKGTTMAYENGDFVPAGSVSAGDILIDGNAIGDVGNV
                     VLRDRKVLSEDGIFIVAITVNRREKKIVARARVHTRGFVYLKKSRDILRESSELINQT
                     VEEYLQGDDFDWADLKGKVRDNLTKYLFDQTKRRPAILPVVMEAK"
     gene            complement(19835..22057)
                     /gene="recJ"
                     /locus_tag="ACL29Z_000403"
     CDS             complement(19835..22057)
                     /gene="recJ"
                     /locus_tag="ACL29Z_000403"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001832038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008409 - 5'-3' exonuclease activity
                     [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded-DNA-specific exonuclease RecJ"
                     /protein_id="HGR0068766.1"
                     /translation="MITPTYEWQFALQVEDADFTKIAKKAGLGPEVARLLFERGIQDQ
                     ESLKKFLEPSLEDLHDAYLLHDMDKAVERIRQAIEERENILVYGDYDADGMTSASIVK
                     ESLEQLGAECRVYLPNRFTDGYGPNASVYKYFIEQEGISLIVTVDNGVAGHEAIALAQ
                     SMGVDVIVTDHHSMPETLPDAYAIVHPEHPDADYPFKYLAGCGVAFKLACALLEEVQV
                     ELLDLVAIGTIADMVSLTDENRILVQYGLEMLGHTQRIGLQEMLDMAGIAANEVTEET
                     VGFQIAPRLNALGRLDDPNPAIDLLTGFDDEEAHEIALMIHQKNEERKEIVQSIYEEA
                     KTMVDPEKKVQVLAKEGWNPGVLGIVAGRLLEELGQTVIVLNIEDGRAKGSARSVEAV
                     DIFEALDPHRDLFIAFGGHAGAAGMTLEVEQLSDLSQVLEDYVREKGADAGGKNKLNL
                     DEELDLEALSLETVKSFERLAPFGMDNQKPIFYIKNFQVESARTMGAGNAHLKLKISK
                     GGASFEVVAFGQGRWATEFSQTKNLELAVKLSVNQWNGQTALQLMMVDARVEGVQLFN
                     IRGKNAVLPEGVPVLDFPGELPNLAASEAIVVKNIPEDITQLKTIFQEQHFSAVYFKN
                     DIDKAYYLTGYGTRDQFAKLYKTIYQFPEFDIRYKLKDLAAYLNIQQILLVKMIQVFE
                     ELGFVTIKDGVMTVNKEAPKREIGESQIYQNLKQTVKDQEMMALGTVQEIYDFLMEKE
                     "
     gene            22334..23092
                     /locus_tag="ACL29Z_000404"
     CDS             22334..23092
                     /locus_tag="ACL29Z_000404"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HGR0068767.1"
                     /translation="MALVEFKNVEKYYGDYHALRNINLRFEKGQVVVLLGPSGSGKST
                     LIRTINGLEAVDKGSLLVNGHQVAGASQKDLVPLRKEVGMVFQHFNLYPHKTVLENVT
                     LAPIKVLGIDKKEAEKTAKKYLEFVNMWDKKDSYPAMLSGGQKQRIAIARGLAMHPEL
                     LLFDEPTSALDPETIGDVLAVMQKLARDGMNMIIVTHEMGFAREVADRIIFMADGEVL
                     VDTTDVDNFFDNPSEPRAQQFLSKIINHESDKVK"
     gene            23103..23897
                     /locus_tag="ACL29Z_000405"
     CDS             23103..23897
                     /locus_tag="ACL29Z_000405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000726191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter substrate-binding domain-containing
                     protein"
                     /protein_id="HGR0068768.1"
                     /translation="MKKKFFLSALLISLFGLAAAKPVQADTSIADIQKRGELVVGVKQ
                     DVPNFGYKDPKTGTYSGIETDLAKMVADELKVKIRYVPVTAQTRGPLLDNEQGDMDIA
                     TFTITDERKKLYNFTSPYYTDASGFLVNKSAKIKKIEDLNGKTIGVAQGSITQRLITE
                     LGKKKGLKFKFVELGSYPELITSLHAHRIDAFSVDRSILSGYTSKRTALLDDSFKPSD
                     YGIVTKKSNTEFNDYLDNLVTKWSKDGSLQKLYDRYKLKPSSHTAD"
     gene            23910..24587
                     /locus_tag="ACL29Z_000406"
     CDS             23910..24587
                     /locus_tag="ACL29Z_000406"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0006865 - amino acid transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HGR0068769.1"
                     /translation="MTDLSSWTAYFQDFGQFFNGFLFTLALAIGSFILAMVLGIFFGA
                     MSTSKRPILRILARIFVEFYQNTPLLVQFVIVFYGLPLISDHTIMIPIYWTAVLCVGL
                     YHGAYIAEVIRSGIQSIPSGQMEAALSQGFTYISAMRLIILPQTFRIILPPLTNQIVN
                     LIKNTSTVAIISGVDLMFVTKSWSALNGNYIPAFLGAALLYFALCFPVAQFGRKMEQA
                     NKKAYSL"
     gene            24597..25256
                     /locus_tag="ACL29Z_000407"
     CDS             24597..25256
                     /locus_tag="ACL29Z_000407"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000443867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0006865 - amino acid transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HGR0068770.1"
                     /translation="MESILEVLTPDNLVFIFKGFGLTLYISLIAIILSTIIGTVLAVM
                     RNGKNSVLRIISSIYIEFVRNVPNLLWIFTIFLVFKMKSTPAGITAFTLFTSAALAEI
                     IRGGLNAVDKGQYEAGMSQGFTSAQILYYIILPQAIRKMLPAIISQFVTVIKDTSLLY
                     SVIALQELFGASQILMGRYFEPEQVFSLYILIALIYFSFNLAISSLSHMLAKRWQQAA
                     E"
     gene            25552..26742
                     /locus_tag="ACL29Z_000408"
     CDS             25552..26742
                     /locus_tag="ACL29Z_000408"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000835812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferric reductase-like transmembrane
                     domain-containing protein"
                     /protein_id="HGR0068771.1"
                     /translation="MKSVKGLLFIIASFILTLLTWMNTSPQFMIPGLALTSLSLTFIL
                     ATRLPLLESWFHGLEKVYTVHKFTAFLSIILLIFHNFSMGGLWGSRLAAQFGNLAIYI
                     FASIILVAYLGKYIQYEAWRWIHRLVYLAYILGLFHIYMIMGNRLLTFNLLSFLVGSY
                     ALLGLLAGFYIIFLYQKISFPYLGKITHLKRLNHDTREIQIHLSRPFNYQSGQFAFLK
                     IFQEGFESAPHPFSISGGHGQTLYFTVKNSGDHTNNIYDNLQAGSKVTLDRAYGHMII
                     EEGRENQVWIAGGIGITPFISYIREHPILDKQVHFYYSFRGDENAVYLDLLRNYAQKN
                     PNFELHLIDSTKDGYLNFEQKEVPEHATVYMCGPISMMKALAKQIKKQNPKTELIYEG
                     FKFK"
     gene            complement(27063..27944)
                     /locus_tag="ACL29Z_000409"
     CDS             complement(27063..27944)
                     /locus_tag="ACL29Z_000409"
                     /EC_number="4.1.2.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004332 - fructose-bisphosphate aldolase
                     activity [Evidence IEA];
                     GO_process: GO:0006096 - glycolytic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="class II fructose-bisphosphate aldolase"
                     /protein_id="HGR0068772.1"
                     /translation="MAIVSAEKFVQAARDNGYAVGGFNTNNLEWTQAILRAAEAKKAP
                     VLIQTSMGAAKYMGGYKVARNLIANLVESMGITVPVAIHLDHGHYEDALECIEVGYTS
                     IMFDGSHLPVEENLKLAKEVVEKAHAKGISVEAEVGTIGGEEDGIIGKGELAPIEDAK
                     AMVETGIDFLAAGIGNIHGPYPVNWEGLDLDHLQKLTEALPGFPIVLHGGSGIPDEQI
                     QAAIKLGVAKVNVNTECQIAFANATRKFARDYEANEAEYDKKKLFDPRKFLADGVKAI
                     QASVEERIDVFGSEGKA"
     gene            complement(28085..29413)
                     /gene="vncS"
                     /locus_tag="ACL29Z_000410"
     CDS             complement(28085..29413)
                     /gene="vncS"
                     /locus_tag="ACL29Z_000410"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000831335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase VncS"
                     /protein_id="HGR0068773.1"
                     /translation="MKRTGLFAKIFIYTFSIFSVLVICLHLAIYFLFPSTYLSHRQET
                     IGQKATAIAQSLEGKDRQSIEQVLDLYSQTSDIKGTVKGEMTEDKLEVKDSLPLDTDR
                     QTTSLFIEEREVKTQDGGTMILQFLASMDLQKEAEQISLQFLPYTLLASFLISLLVAY
                     IYARTIVAPILEIKRVTRRMMDLDSQVRLRVDSKDEIGNLKEQINSLYQHLLTVIADL
                     HEKNEAILQLEKMKVEFLRGASHELKTPLASLKILIENMRENIGRYKDRDQYLGVALG
                     IVDELNHHVLQILSLSSVQELRDDRETIDLLQMTQNLVKDYALLAKERELQIDNSLTH
                     QQAYLNPSVMKLILSNLISNAIKHSVPGGLVRIGEREGELFIENSCSSEEQEKLAQSF
                     SDNASRKVKGSGMGLFVVKSLLEHEKLAYRFEMEENRLTFFIDFPKVVQD"
     gene            complement(29410..30066)
                     /gene="vncR"
                     /locus_tag="ACL29Z_000411"
     CDS             complement(29410..30066)
                     /gene="vncR"
                     /locus_tag="ACL29Z_000411"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor VncR"
                     /protein_id="HGR0068774.1"
                     /translation="MKILIVEDEEMIREGVSDYLTDCGYETIEAADGQEALEQFSSYE
                     VALVLLDIQMPKLNGLEVLAEIRKTSQVPVLMLTAFQDEEYKMSAFASLADGYLEKPF
                     SLSLLKVRVDAIFKRYYDTGRIFSYKDTKVDFESYSASIAGQEVPINAKELEILDYLV
                     KNEGRALTRSQIIDAVWKATDEVPFDRVIDVYIKELRKKLDLDCILTVRNVGYKLERK
                     "
     gene            complement(30115..30198)
                     /gene="pep27"
                     /locus_tag="ACL29Z_000412"
     CDS             complement(30115..30198)
                     /gene="pep27"
                     /locus_tag="ACL29Z_000412"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_198523890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative autolysis signal peptide Pep27"
                     /protein_id="HGR0068775.1"
                     /translation="MRKEFHNVLSSGQLLTDKRPARDYNRK"
     gene            complement(30378..31757)
                     /gene="vex3"
                     /locus_tag="ACL29Z_000413"
     CDS             complement(30378..31757)
                     /gene="vex3"
                     /locus_tag="ACL29Z_000413"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease subunit Vex3"
                     /protein_id="HGR0068776.1"
                     /translation="MLHNAFAYVTRKFFKSIVIFLIILLMASLSLVGLSIKGATAKAS
                     QETFKNITNSFSMQINRRVNQGTPRGAGNIKGEDIKKITENKAIESYVKRINAIGDLT
                     GYDLIETPETKKNLTADRAKRFGSSLMITGVNDSSKEDKFVSGSYKLVEGEHLTNDDK
                     DKILLHKDLAAKHGWKVGDKVKLDSNIYDADNEKGAKETVEVTIKGLFDGHNKSAVTY
                     SQELYENTAITDIHTAAKLYGYTEDTAIYGDATFFVTADKNLDDVMKELNGISGINWK
                     SYTLVKSSSNYPALEQSISGMYKMANLLFWGSLSFSVLLLALLLSLWISARRKEVGIL
                     LSIGLKQASILGQFITESILIAIPALVSAYFLANYTARAIGNTVLANVTSGVAKQASK
                     AAQASNLGGGAEVDGFSKTLSSLDISIQTSDFIIIFVLALVLVVLVMALASSNLLRKQ
                     PKELLLDGE"
     gene            complement(31809..32456)
                     /gene="vex2"
                     /locus_tag="ACL29Z_000414"
     CDS             complement(31809..32456)
                     /gene="vex2"
                     /locus_tag="ACL29Z_000414"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000173730.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding subunit Vex2"
                     /protein_id="HGR0068777.1"
                     /translation="MTLLQLQDVTYRYKNTAEAVLYQINYNFEPGKFYSIIGESGAGK
                     STLLSLLAGLDSPVEGSILFQGEDIRKKGYSYHRMHHISLVFQNYNLIDYLSPLENIR
                     LVNKKASKNTLLELGLDESQIKRNVLQLSGGQQQRVAIARSLVSEAPVILADEPTGNL
                     DPKTAGDIVELLKSLAQKTGKCVIVVTHSKEVAQASDITLELKDKKLTETRNTSK"
     gene            complement(32469..33746)
                     /locus_tag="ACL29Z_000415"
     CDS             complement(32469..33746)
                     /locus_tag="ACL29Z_000415"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001068247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HGR0068778.1"
                     /translation="MNPIQRSWAYVSRKRLRSFILFLILLVLLAGISACLTLMKSNKT
                     VESNLYKSLNTSFSIKKIENGQTFKLSDLASVSKIKGLENVSPELETVAKLKDKEAVT
                     GEQSVERDDLSAADNNLVSLTALEDSSKDVTFTSSAFNLKEGRHLQKGNSKKILIHEE
                     LAKKNGLSLHDKIGLDAGQSESGKGQTVEFEIIGIFSGKKQEKFTGLSSDFSENQVFT
                     DYESSQTLLGNSEAQVSAARFYVENPKEMDGLMKQVENLALENQGYQVEKENKAFEQI
                     KDSVATFQTFLTIFLYGMLIAGAGALILVLSLWLRERVYEVGILLALGKGKSSIFLQF
                     CLEVVLVSLGALLPAFVAGNGITTYLLQTLLASGDQASLQDTLAKASSLSTSILSFAE
                     SYVFLVLLSCLSVALCFLFLFRKSPKEILSSIS"
     gene            complement(33883..34167)
                     /locus_tag="ACL29Z_000416"
                     /pseudo
     CDS             complement(33883..34167)
                     /locus_tag="ACL29Z_000416"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000040325.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="group II intron reverse transcriptase/maturase"
     gene            complement(34310..34909)
                     /locus_tag="ACL29Z_000417"
     CDS             complement(34310..34909)
                     /locus_tag="ACL29Z_000417"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001166174.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0068779.1"
                     /translation="MQILCYFTITVVAKPNNSGEVHLDVSIEDNQGGSGHNFSSVSSS
                     SQTAKYEETGYNNNLSLYTTIDKTSDATALLKLKLNNVDNQPATEVLSSGITVKLNAK
                     DNAGNWTSASNKKEITVKIVSAKPTYPDKILVKNPDNIKDTEKNAIIEKLKEANKNYP
                     VGAPTFAKGEGEHANDIVATYSDGTTYYVPLNDVTKYAR"
     gene            complement(35046..35930)
                     /locus_tag="ACL29Z_000418"
     CDS             complement(35046..35930)
                     /locus_tag="ACL29Z_000418"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844585.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HGR0068780.1"
                     /translation="MRAKELQDWFPEARISDQPVEKEGYLTLPLASQQWILLEEAGLS
                     EREKQLVALLTQQEQARSLNPWYSYLVEGKGQAPQVFKKIQLVYCHLSYFQQENLTSW
                     LDMMRTLFPNCQTVLQVGAQDYVFVLQQDKYTSVRDILSDTIEAVEYDFGLRLSIMLG
                     QVWSQTGHQALSDLIKAERDLFKTWWRQGHQGVHTFSQLYLWSMGERLVDLKPIKECL
                     HQMILDQDQIQEIILSLWENSAVLTKTAQQLYLHRNSLQYKIDKWEELTGLQLKELTD
                     LTLCYQLILGSLSTIVGL"
     gene            complement(35934..36320)
                     /locus_tag="ACL29Z_000419"
     CDS             complement(35934..36320)
                     /locus_tag="ACL29Z_000419"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006148900.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Mini-ribonuclease 3"
                     /protein_id="HGR0068781.1"
                     /translation="MIDVNLINGIALAFEGDAVYSMYIRRHLILKGMTKPNKLHQEAT
                     KYVSAKAQARLISLMLEEQILTEKEEEIYKRGRNTNSHTKAKNADVVTYRMSTGFEAV
                     MGYLHMTENLERLESLVSWCIQKVEG"
     gene            complement(36313..37656)
                     /gene="cysS"
                     /locus_tag="ACL29Z_000420"
     CDS             complement(36313..37656)
                     /gene="cysS"
                     /locus_tag="ACL29Z_000420"
                     /EC_number="6.1.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002916477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004817 - cysteine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006423 - cysteinyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine--tRNA ligase"
                     /protein_id="HGR0068782.1"
                     /translation="MIKIYDTMSRDLREFVPIEDGKIKMYVCGPTVYNYIHVGNARST
                     VAFDTIRRYFEYRGYKVAYISNFTDVDDKIINRAREEGITPQEVADKYIAAFREDVTA
                     LGVKPATRHPRVVEFMADIIRFVEDLIEKGFAYESQGDVYFRVEKSHNYAKLANKTLE
                     DLDLGASGRTDEETARKENPVDFALWKSSKPGEISWDSPWGPGRPGWHIECSVMSTEI
                     LGDTIDIHGGGADLEFPHHTNEIAQSEAKTGKAFANYWMHNGFVNIDNVKMSKSLGNF
                     ITVHDALKTLDGQVLRFFFATQHYRKPINFTEKAVRDAETNLKYLKNTYEQPFTGNVD
                     AQELQNFKDKFVAAMDEDFNAANGITVVFEMTKWINSGNYDASVKQALADMLEIFGIV
                     FVEEVLDAEIEDLIQKRQEARANRDFATADQIRDQLVTQGIKLLDTKDGVRWTRD"
     gene            complement(37738..38622)
                     /locus_tag="ACL29Z_000421"
     CDS             complement(37738..38622)
                     /locus_tag="ACL29Z_000421"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000613615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HGR0068783.1"
                     /translation="MIQARNKLSQEELSEAKKVINCCQNYDGTYRDPYLSNMLNFDPN
                     MPAFFLYYEKGELVGLLTVYADDQDVEVTILVHPGHRRQGIARALFTSFERETASFPI
                     RSVTFQTERIFLENHPDFASNWGLIEDEETETWLGKDRRPYPLANVSHLEVLLADSSY
                     QDQISQLKFQAFSEEHESREVVDRYVAEALKDPESRLYILLKDGQVIGTCTVDLSTNT
                     NYFYGLAISEPERGKGYGSYLAKSLVNQLIEQNDKEFQIAVEDSNVGAKRLYEKIGFV
                     KQTQVVYLNEKGARDSEV"
     gene            complement(38634..39251)
                     /gene="cysE"
                     /locus_tag="ACL29Z_000422"
     CDS             complement(38634..39251)
                     /gene="cysE"
                     /locus_tag="ACL29Z_000422"
                     /EC_number="2.3.1.30"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000539958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0009001 - serine O-acetyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0006535 - cysteine biosynthetic process
                     from serine [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="serine O-acetyltransferase"
                     /protein_id="HGR0068784.1"
                     /translation="MGWWRETIDIVKENDPAARTTLEVLLTYPGVKALAAHRLSHFLW
                     KHGFKLLARMYSQFWRFWTQIEIHPGAQIDSGVFIDHGSGLVIGETAIVEKGVLLYHG
                     VTLGGTGKDCGKRHPTVRKGALISAHAQVIGPVEIGENAKVGAAAVVVADVPSDVTVV
                     GIPAKIVRLHGKKDEPVIHEVEEKREYYVNKLEQAKDASHRSSGL"
     gene            complement(39267..41480)
                     /gene="pnp"
                     /locus_tag="ACL29Z_000423"
     CDS             complement(39267..41480)
                     /gene="pnp"
                     /locus_tag="ACL29Z_000423"
                     /EC_number="2.7.7.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001854499.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0004654 - polyribonucleotide
                     nucleotidyltransferase activity [Evidence IEA];
                     GO_process: GO:0006402 - mRNA catabolic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="polyribonucleotide nucleotidyltransferase"
                     /protein_id="HGR0068785.1"
                     /translation="MAKQVFQTTVAGRELIVETGQVAKQANGSVVVRYGESTVLTAAV
                     MSKKMATGDFFPLQVNYEEKMYAAGKFPGGFMKREGRPSTDATLTARLIDRPIRPMFA
                     EGFRNEVQVINTVLSYDENASAPMAAMFGSSLALSISDIPFDGPIAGVQVGYVDGQII
                     INPSQEQAEQSLLELTVAGTKHAINMVESGAKELSEEIMLEALLKGHEAVKELIAFQE
                     EIVAAVGKEKAEVELLHVDAELQAEIIAAYNSDLQKAVQVEEKLAREAATQVVKDQVT
                     AVYEEKYADHEEFDRIMRDVAEILEQMEHAEVRRLITEDKVRPDGRKVDEIRPLDAVV
                     DFLPRVHGSGLFTRGQTQALSVLTLAPMGETQIIDGLDLEYKKRFMHHYNFPQYSVGE
                     TGRYGAPGRREIGHGALGERALAQVLPSLEEFPYAIRLVAEVLESNGSSSQASICAGT
                     LALMAGGVPIKAPVAGIAMGLISDGNNYTVLTDIQGLEDHFGDMDFKVAGTRDGITAL
                     QMDIKIQGITAEILTEALAQAKKARFEILDVIEATIPEVRPELAPTAPKIDTIKIDVD
                     KIKIVIGKGGETIDKIIAETGVKIDIDEEGNVSIYSSDQDAINRAKEIIAGLVREAKV
                     DEVYRAKVVRIEKFGAFVNLFDKTDALVHISEMAWTRTNRVEDLVEIGDEVDVKVIKI
                     DEKGRIDASMKALLPRPPKPEHDEKGEKSERPHRPRHQKDHKPKKEFTETPKDSE"
     gene            complement(42167..43033)
                     /gene="metF"
                     /locus_tag="ACL29Z_000424"
     CDS             complement(42167..43033)
                     /gene="metF"
                     /locus_tag="ACL29Z_000424"
                     /EC_number="1.5.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000089969.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005829 - cytosol [Evidence IEA];
                     GO_function: GO:0004489 - methylenetetrahydrofolate
                     reductase (NAD(P)H) activity [Evidence IEA];
                     GO_process: GO:0009086 - methionine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="methylenetetrahydrofolate reductase [NAD(P)H]"
                     /protein_id="HGR0068786.1"
                     /translation="MSRQTPSLSFEVFPPNPAVGNDNIISALQDMQELAPHFISVTAS
                     NNKFNIKETTVRLADFIQNDLAIPTIAHLPAIYLTKDKVAETIADLDKVGVQKILALR
                     GDIIPDVEPQKDFRYATDLIEFIKEQTPHFDIIGACYPEGHPDSPNQISDIQNLKKKV
                     DAGCSSLVTQLFFDNERFYDFQDKCILAGIDVPIHAGIMPILNRNQALRLLKTCENIH
                     LPRKFKAILDKYEHDPESLRAAGLAYAVDQIVDLVTQDVAGVHLYTMNNADTAKYIHQ
                     ATHALFNHQSLG"
     gene            complement(43097..45346)
                     /gene="metE"
                     /locus_tag="ACL29Z_000425"
     CDS             complement(43097..45346)
                     /gene="metE"
                     /locus_tag="ACL29Z_000425"
                     /EC_number="2.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009729869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003871 -
                     5-methyltetrahydropteroyltriglutamate-homocysteine
                     S-methyltransferase activity [Evidence IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_process: GO:0008652 - amino acid biosynthetic process
                     [Evidence IEA];
                     GO_process: GO:0009086 - methionine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="5-methyltetrahydropteroyltriglutamate--
                     homocysteine S-methyltransferase"
                     /protein_id="HGR0068787.1"
                     /translation="MSTTIIGFPRLGEFRELKFTTEKYFRKEISEEELLAAAKDLRAK
                     HWNIVKEKGITEIPSNDFSHYDNFLDAAFLFNVVPASVQNLDLSDLERYFALGRGYQG
                     EKGDVRALPMKKWFNTNYHYIVPKFEKDTQVKLAGHKIFDEFQEAKELGLNTRPVLVG
                     PFTFLQLSDFEEGVKADDFVDSLVAAYQEVFAKLAELGATRIQLDEAALVKDLTAEEK
                     ALFLNLYNKLLADKKGLEVLLQTYFGDVRDVYADLVNLPVDAIGLDFVEGKKTLELVK
                     GGFPADKTLYVGIVNGKNIWRNNYEKSLAVLEQIPAENIVLTSSCSLLHVPFTTANEE
                     FEPALLNHFAFAVEKLDEIRDLDAIRNGQGSEALAANKELFATERVGENAELRARIAG
                     LTDADYTRLPAFAEREAIQEEAFKLPALPTTTIGSFPQTKEVRAKRLAYRKGELSQKE
                     YDAFLAETIDEWIKWQEDIDFDVLVHGEFERNDMVEYFGQNLSGYLFSKNGWVQSYGM
                     RGVKPPIIWGDVTRLNPITVKWSSYAQSRTNKPVKGMLTGPVTILNWSFPREDISIKD
                     STLQIALAIKDEVLDLEAAGVKIIQIDEAALREKLPLRRSDWYEDYLDWAIPAFCLVH
                     STVAPDTQIHTHMCYSEFTDIIPAIDNMDADVISFEASRSNLEILDELKAKNFQTEVG
                     PGVYDIHSPRVPNEGEIDNTIEAILAKVPSKKVWINPDCGLKTRGIPETKESLIRLVE
                     AAKAAREKL"
     gene            complement(45607..45873)
                     /locus_tag="ACL29Z_000426"
     CDS             complement(45607..45873)
                     /locus_tag="ACL29Z_000426"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001808618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HGR0068788.1"
                     /translation="MEGCPSELFSKEEILESDMRVAIMSELIEARYEQGISQKKLEEV
                     SGISQPVIARMETGKTSPQLDTVLKVLASLGKTLAIVPLEQGKS"
     gene            complement(45999..46402)
                     /locus_tag="ACL29Z_000427"
                     /pseudo
     CDS             complement(45999..46402)
                     /locus_tag="ACL29Z_000427"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001155321.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
     gene            46558..47559
                     /locus_tag="ACL29Z_000428"
     CDS             46558..47559
                     /locus_tag="ACL29Z_000428"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000597989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease/exonuclease/phosphatase family
                     protein"
                     /protein_id="HGR0068789.1"
                     /translation="MIKTFLSALSVILFSIPIITYSFFPSSNLNIWLSTQPILAQIYA
                     FPLATATMAAILSFLFFFLSFYKKNKQIRFYSGILLLLSLILLLFGTDKTLSSASNKT
                     KTLKLVTWNVANQIEAQHIERIFSHFDADMAIFPELATNIRGEQENQRIKLLFHQVGL
                     SMANYDIFTSPPTNSGIAPVTVIVKKSYGFYTEAKTFHTTRFGTIVLHSRKQNIPDII
                     ALHTAPPLPGLMEIWKQDLNIIHNQLASKYPKAIIAGDFNATMRHGALAKISSHRDAL
                     NALPPFERGTWNSQSPKLFNATIDHILLPKNHYYVRDLDIVSFQNSDHRCIFTEITF"
     gene            complement(47627..50032)
                     /gene="pheT"
                     /locus_tag="ACL29Z_000429"
     CDS             complement(47627..50032)
                     /gene="pheT"
                     /locus_tag="ACL29Z_000429"
                     /EC_number="6.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002897790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000287 - magnesium ion binding [Evidence
                     IEA];
                     GO_function: GO:0004826 - phenylalanine-tRNA ligase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006432 - phenylalanyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanine--tRNA ligase subunit beta"
                     /protein_id="HGR0068790.1"
                     /translation="MLVSYKWLKELVDIDVPSQELAEKMSTTGIEVEGVESPAAGLSK
                     IVVGEVLSCEDVPETHLHVCQVNVGEEEERQIVCGAPNVRAGIKVMVALPGARIADNY
                     KIKKGKIRGLESLGMICSLGELGISDSVVPKEFADGIQILPENAVPGEEVFSYLDLDD
                     EIIELSITPNRADALSMCGVAHEVAAIYDKAVNFKEFTLTETNEAAADALSVSIGTDK
                     APYYAARILDNVTIAPSPQWLQNLLMNEGIRPINNVVDVTNYILLYFGQPMHAFDLDT
                     FEGTDIRVREARAGEKLVTLDGEERDLDVNDLVITVADKPVALAGVMGGQATEISEKS
                     SRVVLEAAVFNGKSIRKTSGHLNLRSESSSRFEKGINVATVNEALDAAASLIAELAGA
                     TVRKGIVSAGELDTSDVEVSSTLADVNRVLGTELSYADVEDVFRRLGFGLSGNADSFT
                     VSVPRRRWDITIEADLFEEIARIYGYDRLPTSLPKDDGTAGELTVTQKLRRQVRTIAE
                     GAGLTEIITYALTTPEKAVEFTAQPSNLTELMWPMTVDRSVLRQNMISGILDTVAYNV
                     ARKNKNLALYEIGKVFEQTGNPKEELPNEINSFAFALTGLVAEKDFQTAAVPVDFFYA
                     KGILEALFTRLGLQVTYTATSEIASLHPGRTAVISLGDQVLGFLGQVHPVTAKAYDIP
                     ETYVAELNLSAIEGALQPAVPFVEITKFPAVSRDVALLLKAEVTHQEVVDAIQAAGVK
                     RLTDIKLFDVFSGEKLGLGMKSMAYSLTFQNPEDSLTDEEVARYMEKIQASLEEKVNA
                     EVR"
     gene            complement(50109..50618)
                     /locus_tag="ACL29Z_000430"
     CDS             complement(50109..50618)
                     /locus_tag="ACL29Z_000430"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000619935.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016747 - acyltransferase activity,
                     transferring groups other than amino-acyl groups [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HGR0068791.1"
                     /translation="MIRKVEMADVEVLAKIAKQTFRETFAYDNTEEQLQEYFEEAYSL
                     KTVSTELGNPDSETYFIMHEEEIAGFLKVNWGSAQTERELEDAFEIQRLYVLQKFQGF
                     GLGKQLFEFALELATKNSFSWAWLGVWEHNTKAQAFYNRYGFEKFSQHHFMVGQKVDT
                     DWLLRKKLR"
     gene            complement(50618..51664)
                     /gene="pheS"
                     /locus_tag="ACL29Z_000431"
     CDS             complement(50618..51664)
                     /gene="pheS"
                     /locus_tag="ACL29Z_000431"
                     /EC_number="6.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013903845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004826 - phenylalanine-tRNA ligase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006432 - phenylalanyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanine--tRNA ligase subunit alpha"
                     /protein_id="HGR0068792.1"
                     /translation="MSTIEEQLKALREETLASLKQITAGNEKEMQDLRVSVLGKKGSL
                     TEILKGMKDVSAEMRPIIGKHVNEARDVLTAAFEETAKLLEEKKVAAQLASESIDVTL
                     PGRPVATGHRHVLTQTSEEIEDIFIGMGYQVVDGFEVEQDYYNFERMNLPKDHPARDM
                     QDTFYITEEILLRTHTSPVQARAMDAHDFSKGPLKMISPGRVFRRDTDDATHSHQFHQ
                     IEGLVVGKNISMADLQGTLQLIVQKMFGEERQIRLRPSYFPFTEPSVEVDVSCFKCGG
                     EGCNVCKKTGWIEIMGAGMVHPRVLEMSGIDATVYSGFAFGLGQERVAMLRYGINDIR
                     GFYQGDVRFSEQFK"
BASE COUNT        14707 a        11851 c         9781 g        15638 t
ORIGIN      
        1 ataaactaac ctcctcatta ttagcaaggc ttctactgat tataacctaa ttcttagact
       61 acttcaagac taactgtcca ataataatct acagataaat catccactct taatcaaatt
      121 ttattcaatc catctactca ttcccaaaag gttgctgtat aatgcaagac atttttctta
      181 ctgattttac ttttccttac cctcaattta gtgagctaat aaattattct tcttcaaaag
      241 gttgagattt atctagtaac tctaaaacat taatggtagg tagcaacatt gcttcactgc
      301 tatcaattgc cgaaactgtt gaaacaatag aacgtaaata aggataaaga atagcagtac
      361 catttacgta tagaatatcg gtgatatttt catctatatt tatttcaaaa tatcctatta
      421 cagttacaga tatttttttc atggcatctt tgtcaactaa agaaacacta agttttacgg
      481 ctccatgact ataatcatct gcatgaccaa ccttaactat gggatataat atatcgaagg
      541 taaatgtgaa caaattgatt agggaattta aaccaacttc taacaatgtg ttatactcaa
      601 tgaaaaccaa agagcaaact aggaaactag ccgtaggttg ctcaaaacac tgttttgagg
      661 ttgtggatag aactgacgaa gtcagtaacc atacgcacgg caaggcgacg ttgacgtggt
      721 ttgaagagat tttcgaagag tattagaaag ctcgatggac tattccagat tcattccact
      781 agatttcgaa atcgagtagg ggataatctc tagcccctct cacaccaccg tacgtgccgt
      841 tcggcatacg gcagttcaac taacttttaa cgcatgtcgt tcaaggtaat aatccaaaca
      901 cgaaaccagt tcacgttttt caaggactgg ttttgatata gcacgtttaa gtaccgactt
      961 ctgagctact aattgatagt ggtcgcccca gccagatacc ttatccgcta tataggcctt
     1021 attatcacgt tcctgttcgt agagccacga tttcgctatc ccttcctctg acgattctta
     1081 tttccagcgt cagacttaaa acggtctatc cccagaccgt tttaatccgc tacctcacga
     1141 tagtcagact tgggaatcgc tattgggttc accggtagca ggtgcccacc gaggacttac
     1201 acctcaaata tataataaaa tgaaataaga acaggacgaa tcgatcagga cagtcaaatc
     1261 aatttctaac aatgttttag aagtagatgt gtactattct agtttcaatc tactatacaa
     1321 catgcccgtc gtacatcaaa aaaagttgag acatagcgtc ttcaactttt ttacattact
     1381 ttaactactg attaaagtga gtttacgtca actttgatac caacaccttg agtagttgtg
     1441 atagtcaagt ttgttacgta agttccttta gctgtagctg gttttgcttt ttggattgtt
     1501 tcgttgaaag ctttaaagtt ttcaaccaat ttttcagctt caaatgatac tttaccgatg
     1561 attgcttgaa cgttacctgc acggtcagca cggtaagtga ttttaccacc tttagactct
     1621 tcaactgctt tagcaacatc cattgttaca gtaccagttt tagggtttgg catcaagtta
     1681 cgtggtccaa ggacacgtcc aagacgtcca acaagagcca tcatatcagg tgtagcgata
     1741 actacgtcga agtccaacca accgtcgttg attttagcaa caaggtcatc ttcaccaaca
     1801 aagtctgcac cagcagcttt tgcttcttca gcttttgcac cacgtgcgaa aacaagaaca
     1861 cgtgaagttt taccagtacc gtttggcaat accattgctc cacggatttg ttggtcagct
     1921 tttttaacgt cgatgttcaa gttgtaagca acttctacag ttgcgtcaaa ttttgcaaag
     1981 ttagtttctt ttgcaagtgc tacagcttct tctacactgt atgcttttgt gctgtcgatt
     2041 ttctcaagag cagcacgaag ttgtttgctt tttttagcca ttttctattc tccttgtaag
     2101 tggttcaatc gattttcatc tcccacgtca cttctcgaaa tgatgaagtc ttgcgggttt
     2161 tcagtctact atttttctct tcctacggcc ttaagctccc ttgctgtacc caagtacaag
     2221 gctcagtcac ttgcctagta tgaaaagcaa ctaatagact gctgtgagat tttctactgt
     2281 gttattgatt agtcaacaac agtgaatccc atagaacgag cagtaccttc gatcatacgc
     2341 attgcagact ctacgtttgc tgcgttcaaa tctggcatct tagtttctgc aatttcttgt
     2401 acttgtgcac gagtaactgt agcaacttta gttttattag gtgtacctga tcctttttca
     2461 acacctgcag cttttttcaa aagaacagca gctggtggtg ttttcgtaac gaaagtaaat
     2521 gatttatctt cgtaaactga gataacaact ggaatgatca taccagcttg gtcagctgta
     2581 cgagcgttga actcttttgt gaatcccatg atgttgatac cagcttgacc aagagcaggt
     2641 ccaaccggtg gagctggtgt agctttacca gcagggattt gcaattttac aagtttttcg
     2701 acttttttag ccatttttaa atcctccttt gtggttttgg cggtaattag agatttttac
     2761 ctcccacaag tatgtttttc acatacccat ccattataca ctatttatct ggaattgcaa
     2821 gagaaaagtt tattttttgt actcaatgaa aatcaaagag caaactagga agctagccgc
     2881 aggctgctca aagtacagct ttgaggttgc agataaaact gacgaagtca gctcaaaaca
     2941 ctgttttgag gttgtgaata gaaccgacgc agtcagtagg taaggcgacg ctgacgtggt
     3001 ttgaagagat tttcgaagag tattaatcga cgtagtctcc gccttcaaag ccatagtatt
     3061 cttccaaact gagaccactt gcagcaattt ctttagcttc ttttcctaca taacgcaggt
     3121 gccattcttc agccatatag cctgtttcct tttccttgcc tttgagataa cggacaacaa
     3181 agccataatc agctgcatga tccaagagcc attgggctgc tttttcttct gtcaccaaat
     3241 caccatcagt cccaatcaca tcaaaggcca agcctgtctg gtgttcgcta tagccaggac
     3301 gggcagagta acggtcagct gctgcctttc catcttggtt gacataatct tgatagagct
     3361 tggtctgagt ttcataactt ctaaaaccac tgtaatgatc actaataggg aaacctgcct
     3421 cttgcatcgc tttgatgagt ttgaccaact cagccttggc tgttggattt tccccgggat
     3481 tatagtcttt cgacaaagga taatgtttat tggctacgat gatttcgtcg tattttcctt
     3541 ggatgctgta gtaatcacct ttattgacca cttctgcttt tttctgggca gccccttgag
     3601 acttactgcc gactgtccca tcagctttgg ctgtctgttc tgtcttagct gtgccatctt
     3661 cattttttgc tttttcttgt gaacaagctg ctagactcaa ggctagcaag gctgtcaaga
     3721 caaggtatct ttttttcatt tctactcctt tatttctaat agtttatcta cttctgacga
     3781 taaacattcg actaatcttt taatctcttc cggttttact tggcaagttt ctgctgtcat
     3841 ttcttcaaag ggaacccacc aaactggccc acgaccttta agaccgtggc cattcatatc
     3901 acctgtccgt cgtggaaaca gatgccaatg aagatgggca tcgccatttc ctagcagttc
     3961 gatattcatt ttctcagcag caaatgcctt ggcaactgcc tcttggacta gactcatttc
     4021 ttcgagaaaa cggagtcttg tttccttttt caaatggtgc aattcggtaa cgtgttcctt
     4081 agctagaaaa agactatatc ctgcaaaata ctggtggtct ccaatcacaa gatagcctgt
     4141 ttccaactct ttgacaaagt aaggattttc ttccttcttg atgaggtcaa ttctctggca
     4201 aatcaggcac atattagtct accaacccac tcttaagata agcatcaacc atacgctctg
     4261 ttgcgaccac cgagtcaata tgagtacgct cataagaatg actagactcg atacccgcac
     4321 caagaagagc gtgtttaact tctgcacctg cagacatagc cgctgaagcg tccgaaccat
     4381 aaaatggata gatatccagc ttgaatggaa tatcttggtt tttagccaag gtcaccaaat
     4441 gttgacggaa gtcatagtga taaggacctg aagcatcctt gacacagatg gacactgtgt
     4501 actcatctgt ttgctgatca tcccccatag ctcccatatc cacagccaga tattcgacta
     4561 cttgagcagg aatattagaa ttagcaccat gccccacttc ttcaaagact gaaaaggcaa
     4621 aatgggttgt tactggcaac tcaatcttct cttccatata aatacgaagc aggttaagca
     4681 aaatcgctgc gctgaccttg tcatccaaat gacgagactt gataaaacct gtatcagtca
     4741 caacagttcg tggatcgaag ctgataaaat caccgacctc aatcccaaga gcacgagttt
     4801 ctttttcatt gcttactttt acatccaaac gcacttccat attgtcctgc gtgcgttctg
     4861 cagttcctgc atccttgtag acatggcaag aagtttggtg gatgaggatg gtgcctgata
     4921 ctttttcacc tgtgctagcc acatgaacgg tacagttttc accttcaatc atgttccaag
     4981 gaaaaccacc gatacggtcc aatttaagac gaccatctgg tttgacagca cgaacaatag
     5041 cacccagcgt atccacatga gcagtcacat agcgatgttg ctcatcattt tgacctttga
     5101 tggtcacatt gacaccaccc ttagctgtgc gaactggctg gtaaccaaaa ccttctagag
     5161 tcttgactaa ataattcgaa atttcacgag taaagcccgt tggcgatgcg atggctgtca
     5221 gttctttgat atattctact gtttgattca tttcttcacc tctttcgcta cctattataa
     5281 cacatttatc atcggataaa aaaagaaaat cactcctgta gacttggcta caaaagtgat
     5341 ttaagtgatt attccatttc aaaaacatcg ctttcttgct tgtttggtag aaccaatgag
     5401 agcaagattc caacaatggc tggcaccaac catgggagag atgccttggc aaaaggaaga
     5461 acgctaacaa gatttgcaag aaactcaacc ttaaacgagc ttcctagtac gcttgcaatg
     5521 gcaataactg taaccacagc aattgtcaac tgcatacctg gttttgaaag ggcaacaaat
     5581 ttgttgacaa tgacaatcat aacgatagca atcgtgattg ggtacaagat aaccaatact
     5641 ggaattgagt acttgataat cgcatcaaga cccaaattgg caatagcaaa tccaatcaag
     5701 gtaaaggctg tcgcataaac cttgtagctg atttgtggga agcgttcatt aaagaactca
     5761 gctgttgaca caatcaaacc aacagtcgtt gtgaagcagg ttacggtaac catagctgca
     5821 aggaagagtt gagctgttga gccaaagatt tcttgagtgg cttgtgacaa gatgtaaaca
     5881 cctggtgttc cacccttcat cgcttcagct ggtactggga aatgatttcc aagaaaacct
     5941 aaaccgatgt aaagagcgct gaaggcaagg gcaacaacga taccaacaac ccaaatagtt
     6001 gaaatgtatt ctttcttact tgaaaatcca agttgtttca aggtttgaac tgcgattacg
     6061 ctaaaggcca ctgaggcaag ggcgtccaag gtattataac cttctaggaa acctgtacca
     6121 aaggcagaag cttgataagc agctgaagca gcttgaggac ttgttccacc atatttgata
     6181 gctcccagaa cgaccaagat aacaatcaaa attgcaaaga ctggcgttaa aatacgtcca
     6241 atgcggtcta agatttttga tggattaagc gaaatcaaat aggctgccgc aaaatacaga
     6301 accgtaaata caatcaagcc aagtccttta tttgcatccg acaaaagggg gctaatccct
     6361 acttcgtaag ctgttgtagc agtacgtggg gtagcaaaga atggaccgat tgacaagtaa
     6421 agaactgaga ggtaaagagt cgcaaaccaa ggcgctatct tcgttgaaat ctcgtagata
     6481 tatcctttag gatttagcgt tccaataata agggtcaaga cggcgatacc aacgcctgaa
     6541 aagacaaaac ctgcgatggc aggaagaaaa tgttctccag atagagcacc tagagaaggc
     6601 ggaaaaatca agttccccgc accaaaaaat attccaaaca ggagcaaacc tgttagggta
     6661 ccttttttag ccataaaaat ctccttcata tttataaaat actgacctag tataccacga
     6721 ttaggagtct gaaaaaagca tcacgaggca aatattaaat gttttcaatt ttcttaaaaa
     6781 taagaattat ctaaaaataa aactctccta cccagtccac accaagtagg agaaatgcaa
     6841 aattttaaag ttcttcaaag gctaacatgc caccctggac attgataaca ttataacctt
     6901 gttctaacag gaattggcaa gcacgcgccg atctcattcc agatttgcaa ataatataat
     6961 gcaagcgatc tttgtccaat taatcataac tatcagccaa ttgactaagc ggtaggttgt
     7021 gggcacattc taaatgaaga gctgcaaact catccacttc tctcacatcc actagagaaa
     7081 gctggtcgtt ttggtaaagc tggtaaaatg cgtcaaaggc tatttctttc attctttttc
     7141 ttctaatact cttcgaaaat ctcttcaaac cacgtcagcg tcgccttacc gtgcgtatgt
     7201 taccgacttc gtcagtttta tctgcaacct caaagctgta ctttgagcag cctacgacta
     7261 gcttcctagt ttgctctttg attttcattg actataaaat ggttttaatt ctttttttca
     7321 aatctggcac tacttctgcc tcaaaccaag gatttttggc catccagatt tgatttcgtg
     7381 gtgatgggtg aactagcgga aaataggctg gcagatagtc tttatagtgt ttcaccctct
     7441 ccgttacctt cccactgatt ttctcctgta aatagtaggc ttgggcatat tgcccaatca
     7501 agagggttaa ctgaatatca ggcaattcct gtaagagctg cggatgccat ttttctgcaa
     7561 aacctgtacg aggcggaaga tcacccgact tgccatgtcc tggaaagtag aaatccatag
     7621 gcaaaacagc aaaataacct gaattgtaaa aggtatcttc atccacacct agccagtccc
     7681 gcaagcggtc accactttta tctttccagt aaaggcctgc ttcttgagtt ttaagtcccg
     7741 gagcctgacc gatgatattg atgcgagcag tttttggcgc tgcaaagaga ggctcaatgc
     7801 cacgctctgt atagctggca ttctgtgaat ccgccatgat agcctgtttg attctttcga
     7861 tttgagacat ctactttccc tccaaaaaga agtccaagca taagatctca gacttctatc
     7921 gttttatttg atcaattcgt aaatagcttc ggcataaatt gctgctgctc ggaaaagatc
     7981 atccaaggcg ataaattcat tggcttggtg catggtatca atcgagtctg ggaacatagc
     8041 accgtaggca actccgcgtt ctagcaagcg accaaaggtt ccaccaccga tgacttgttc
     8101 atgaccttta aggccagttt gtttttcata gatattcaac aaggtttgca caagtggatc
     8161 ttccattggc acatagtgag gcgtgtgacc gtgttcagac agactaacag aaacaactgg
     8221 caagttttca aggattgact tgatttgttc tggacttgtt ccttttggat agcggatgtt
     8281 gagggcaatg gtattatcag cacttgtttc atcgaagcgg aagacgccgg cattcataga
     8341 aagagcaccc atcttttcat ccacatgagc aatcttaaga ttttcaccct catgatcgtt
     8401 caagagaatt ttacctgcga tgtcaaggta gtctttggct ggaccagcaa agccaaactg
     8461 gctgaggaag agggcaaggt aagttgcgcc attgacacct gaagcaggca tagcaccgtg
     8521 ggctgattta ccaatgatcg tcaccttgta tttgccagct tcttcttgga gttctcctct
     8581 aagtttgtgt tctgcaacaa aggcatctag tttagcttgc aagtcagcca aatcacctga
     8641 aacgactgct gttgctgatt ctggtaccat attttcacgt aaaccacctg taaagctgtg
     8701 aagacgggca gcacctgtat tttctcctgc aaagtggagg tattccgtga tatttccttt
     8761 ttcaccattg atgattggaa attcagcatc tggagagaaa ccgaaatctg gtttggcaag
     8821 tcctacgtgc tcaaagtagt agtccatgtc tgcccagcct gattcttcgt ctgttccaac
     8881 gatgaagcga actttcttag aagttggaag acccaattct ttgatgattt tcaaaccata
     8941 gtaacaagct gttgtaggac ccttatcgtc cgaagccccg cgcgcataaa ggcgaccatc
     9001 tttgatagtt ggtgtgtaag gatctgtgtc ccaaccgcta ccagcaggca ccacatccat
     9061 atgggcaaag attccgagaa cttcttctcc atcaccaaac tcaaaatgtc ctgcgtagtt
     9121 atcgacattc ttagttgggt agccatcgcg gtctgcgatt tcaaggaatt tctccaaggc
     9181 ttttactgga ccaggtccaa atggatgctg ggcatcagcc ttgctatcat cacgttctga
     9241 gttgatttcc aaaaggctaa acaagtcagc caagaggtct tctttgcgtt tttctacttc
     9301 tgctgtaaaa tcaattgctg tcattttttc ttctttctat cttttctcga tgatttcatc
     9361 tactggcaag cggtagcttg gttccaattt gtcgtctgtg taacccactg tgatcaagag
     9421 ttctgggcgg aaacggtctt cgatttccaa aacttcatta acttttgatt tgtcaaaacc
     9481 aaggataata ttggaaccaa ttccttggtc tgtaagagcg agaaccaagt tcatagcaac
     9541 caaacctgca ttgagtgcta ggtagtcgct gacttgttgt tcattgtagc gtgcaaattc
     9601 agctggcaaa tttttcatga agtattgaag ttgttcttct gagaaattgt tagcaccacc
     9661 aactcgggca atcttacgag cgcgtttggc aaggtctgta tctgtaaata gggcaatagt
     9721 tacaggtgct gatgatacct gctcaaagtt tgaaccataa gccaactttg ccagttcagc
     9781 atttttctca cgaacaacta caaatttcca aggctggctg ttgtgggcgc ttggcgccaa
     9841 ggttgcaatt tcgatagccg tacgcacatc ttttggatca acaggcttat cagtgaaatg
     9901 cttggtcgca tgacgttttt tatttaattc aagaaatttc ataatcgatt tccttttcta
     9961 attctactgc ttccattcta ccataatttg aaagagcttg cagggatttt tcatgattaa
    10021 gtttttctat cacagacata aaagatatat attggtttat caggaaagtt tctgataaac
    10081 tagcaagtac tttacatttg aatggagaca gtatgaaaaa atttagccta ttactagcta
    10141 tcctaccatt tttggttgcc tgtgggaatc aagctacacc caaagagtcc agctctcaaa
    10201 agacaatcgt ccttgctaca gctggcgatg tgccaccatt tgactacgaa gacaagggca
    10261 atctgacagg cttcgatatc gaagtcctaa aagcagtgga tgaaaaactc agcgattacg
    10321 agattcaatt ccaaagaact gcttgggaga gcatcttccc aggacttgat tctggtcact
    10381 atcaagcagc agctaataat ttgagttaca caaaagagcg cgctgaaaaa tacctctact
    10441 cgcttccaat ttccaacaat cccctcgtcc ttgtcagcaa caagaaaaat cctttgactt
    10501 atcttgacca gatcgctggt aaaacaacac aagaggatac cggaacttct aacgctcaat
    10561 tcatcaataa ctggaatcag aaacacactg ataatcccgc tacaattgat ttttctggtg
    10621 aggatattgg taaacgaatc ctagaccttg ctaacggaga gtttgatttc ctagtttttg
    10681 acaaggtatc cgttcaaaag attatcaagg accgtggttt agacctctca gtcgttgatt
    10741 taccttctac agatagcccc agcaactata tcgttttctc aagtgaccaa aaagagttta
    10801 aagagaaatt tgataaagcg ctcaaagaac tctatcaaga cggaaccctt gaaaaactca
    10861 gcaataccta tctaggtggt tcttacctcc cagatcaatc tcagttacaa taacactctt
    10921 cgaaaatctc ttcaaaccac gtcagcttta tctgcaacct caaagctgtg ctttgagcaa
    10981 cctacggcta gcttcctagt ttgctctttg attttcattg agtataagat atactaaaag
    11041 cgattggacc agccaatcgc ttttttagtt tgcattggct attttaggaa actcttacaa
    11101 aaaatcaaaa aaattcttca catcctctac atacccatgc ttttctatta agctggctaa
    11161 taattccaga ttgtgcccct gatagttatc gtcacgacgc agttcttcat acatttcgat
    11221 aaagggaagc cccttggact tggccaattc taactcagct tcgtaatcat aagcaacttt
    11281 acgaaattgg atattgagta attccccatc ttcaacttct atcacggcat actgggcacg
    11341 gtgatttttt aacgcctccc aattaaaata gggcatgcca atcgaccctg gattgatgat
    11401 ttgttgccct tgacttccat aacgaagcaa ctgcttgtga acatgaccat aaactgccac
    11461 gtccgtttcc gcatctagca gttggtcaaa tttctctgta tcattctcaa ctagcaagtc
    11521 accaccatag tttttgtcag gtaaattatg agagatagaa aagcgcaatc cgtcaatttc
    11581 tttcttttcc agcaaaggca agcttcgtag ccagacaatc gttgcaggat ccattcgctc
    11641 catcaaatac tgtgtcatac gcaagagctg aacttcctgt gggtcttcta agccatattg
    11701 cccatctaaa gcctcaagga cacgatcatc ccaattgcct cgaacacttg ctgtgatagg
    11761 aaggtccttt agcagggcga ctaagtcatt tgcgcctgga ccaggaagaa aaatatctcc
    11821 cagaagccaa tattcactgg ccccttgatt tttagcatct gcaatcactg cttctagcgc
    11881 cgtcgcattg ccatgaacat ctgataaaat tgcgatttta tggttcattg tggtttcctt
    11941 ccgtttggta atctactctt tcttctgcta cttgaagcaa ggcttctccc tgcgggttca
    12001 actttctttg cacagcctct gcaacgactc taggtacccc aacttcgaca atctcatcca
    12061 cactggcttc cttgattttg gtcaaagact tgaaatgcct catgagattt tgcttgcgtt
    12121 taggtcccag accatcaatc ccatccaatt gagatgagaa agaatttttg gagcgcagtt
    12181 ggcggtggaa agtgatagca aagcggtgga cctcatcttg gatgcgttgg aggaggaaaa
    12241 attcctgaga attgcgagac aagtccacca cctcaagcgg atctccaaag agcaattcat
    12301 gggtttggtg cttatcattc ttttgcagcc cagcaattgg aatatccaag cccagttcct
    12361 cttggataac ctgcttagcg atattgactt gaccttgccc cccatcaatc acaatcaaat
    12421 ctggaggagt caaagcctca cgctgtactc gaccatagcg tctgcgaatg acctctctca
    12481 tgctggcata gtcgtctggt ccaacaaccg tttttatctt gtacttacgg taatccttct
    12541 tactcggttt accgttgaca aagaccacca tagccgaaac agggctagtt cccatgatat
    12601 tagagttatc gaaggactcg atacgtactg gggtcgggat ttggagcaaa cgccctagat
    12661 tttcaatagc tccttgggtc ttttcgacag atttttctag cagattgaac ttctgctcta
    12721 gactaacacg agcatttttt atggctagat tgaccagttg ttttttctct ccacgttgag
    12781 gcttaagaat cttggaatcc accaaggcct tgacagcctc ttcgtcaata tcctgcggaa
    12841 tcagtacctc attgggaact agatgagatt tttcttgata gaattgtcct acataggtca
    12901 aaaaatcctc atctggatca ttgaagtagg ggaagagatt gacatcgcgc tcgataagct
    12961 taccctgacg gacaaagaaa acctgcacac acatccagcc cttatccaca tagtagccaa
    13021 agacatcgcg attttgcaaa tctttcgcca tgacccgttg cttggttcga agcgttccaa
    13081 tagcctgaat caggtcacgg tattccgccg cacgttcaaa ctccatactt tgtgctgcta
    13141 ctgccatttt actcttgaga tcatcgatga ttttgtcatc ctgacctttc agaaaatcag
    13201 acacctcctg agccatagac ttgaaataag cctcatcctt cttacagatg gtgtgggcca
    13261 tacactggcc gatatggtaa taaaaacaga ccttagaggg cgggttggta cattttcgaa
    13321 aagggaaaat cctatctaga agtcgcttga tttcattggc tgcccccaca tctggataag
    13381 ggccaaaata aagaccaccg tcctttttga cctgacgagt aatgataagc cgtggatagc
    13441 gctcattggt gattttgatg aaaggatagg acttgtcatc cttgagcatg atattgtact
    13501 tgggcttgtt ttccttgatc aggttgattt ctaggagaag tgcctcaata ttagactccg
    13561 taacaataaa ttcaaaatcc acaatttcag acaccagagc ctctgtcttg gtatcatgac
    13621 ttccacgaaa ataggaccgt actcgattac gcagattttt agcctttcct acatagataa
    13681 tggtgccatt tttatcctta tgaatgtagc aaccagggct ggtcggcaag agctctagtt
    13741 ttgatttaat caagttgttc atagttccat tatagcaaaa aaagtaggga aagatagtac
    13801 cctactcact agtctcatat atttttcgga ggtttgcaac atcctcttcc tggataccat
    13861 aaaaggaacc tgctggttgc atgacagact tctcatctgt atggtccaag ccaatcgcat
    13921 gacctaactc atgttctgcc gtatggacaa ggcgttcata ggagtagcca tagtatggat
    13981 tggacaaata ataatgattc aaccgcaccg ttacggacaa gaattgccct gttaagagat
    14041 tagtttgact ttccgcctct cctgccacag gagtgcctcc gtcgttcatc tccgtagccg
    14101 taatatccgc cttactagac tcagtcacga gttcaaagtt aaaagcacca gtttgattcc
    14161 agttctggat tgcttctaaa taagcctctt gaaagcgtga atccatctgc ggatccaggt
    14221 aaatacgagc agaggcctgt gcccaccttc cttcagaatg ctggtgacta tctgtctggc
    14281 ttaacttagg cagttgccct gttttctccc attggtcaat actttgttga ccaattttta
    14341 ctgaccgttc tgcttgcttt agcgctcctt gaaaatcccc gttcagatac cagagaagtc
    14401 cgaaagcaag cacacataag agcacaacta tccaaaccag acgccaaaac aaacgccaca
    14461 caaaagaaaa gaaagcccct atcaaacgaa aaagccagcg catgtctctc cacctttcta
    14521 gcaaataaga attattttac taaaagaagc taaaagaaat ctaaatactg actttttcat
    14581 cttaacgtcc tactattttt ttgagtaact ggatagcttt gtattttaaa ggcgatggat
    14641 ggtaacggaa agtacccgct ttgcgtacaa tatagccatt aaaattctgt ttaaaacgca
    14701 aaacaccatc acttccatca aaaatccctt gaatgcctag gaagttgtat ttaggtattc
    14761 cacgttttat gctttccaac ataacatatt tttgaagcag ggcaggggca tagaacttat
    14821 taaactcagt gtaggaacca ctaaagagat aagtcgtttc ctgaggcata taaacaaata
    14881 aactcccagc taaaacaata tcttcttctc catatttttc aatcaagtct cgcgcttctg
    14941 cttttcgaac ttcaaacgtt tcaaattgac tagaatattc tctcagttga ttttgttttt
    15001 tctcagaatg aggattttta ctcaaatcaa gtcgcaactt gtccaagttt tcttctagtt
    15061 tactttgttc accttgcaat ttgctcatat agtccgaaaa atttaagctt gctatgagaa
    15121 actccgcttg ttctccaaaa gtatcataaa aatgctcata atattctaaa cttttatcac
    15181 tatattctct acgttcagag gtttcttttg ttatattctt aaaaatcgat agttcttcac
    15241 gttttaactt tttcaaccga atgccaaagg tttcagcctt tttcaccaag ggtttaccct
    15301 ttttgctaaa acttttaagc aaactctttt cagttaattc agttaaatct ttatagtata
    15361 accaatctgg ttctccacct gggtaacctg ttgttaagcc atcaaattga taacctaaat
    15421 cagtcaaacc ttgaataata ctttttttct cagcatctat tgaattacct tggctatcaa
    15481 aagtttgata agtttcataa ggttttacaa gcaactctaa tacaccattt tgcttggcat
    15541 attcttttaa ctctgcataa aaaactggaa gagcatcttg ttgggtataa atcggccccg
    15601 aattgagttc catatgcaga ccacccagca tgggcaagct ataaaccaga gctgcaactt
    15661 gaatttctcc ttcttgtttc aaagcaagat aaacaattcg agcccctctt ttttctagca
    15721 aatcccccat ctggacagat tgcataaagg aacgagaaga aacctgatca gaataagtct
    15781 gaaactcttc tttcgtgagt gttgttagtg ccatatactt actttctatg tttttttctt
    15841 aatgttttac ggaaatcaag agcaagtctt aacagaggat agagaggatg agtgggcatt
    15901 gtaaattcac ccaagtattc ttcaatcgtt ggattaaatt tttccttaaa atgataaagt
    15961 ccaccattga gagagttttc aacaccacct aaattttgcc aaaccatacc tcgctcaaag
    16021 gcatagcgag ccgtttcata ccatgttaaa attggtgcat tgtaacgttt aaaatcatca
    16081 tccataccag catatatatt gacagaggta gtaccaaatt ccaaactcaa agtagccgct
    16141 aaaggaactc tcgcttgacc tacatctata tattcctgca agaaggtcaa ttcctctaac
    16201 aaacgttctt tttccttctt ctgcgcttct acttttgaaa ttcgagtcga ctcagtaaac
    16261 gtctcttcca aggctctatt tttcgctaac tgttcttcta attcttgcga acgtttagaa
    16321 acatccaagg tggccaaggt gatataggcc ttgtccttaa aattatctaa caatttttta
    16381 taataggctt cattcctcaa atgaatctct tttcgcttct cagttttttt catcaactcc
    16441 gaaaatgaat ctaatagttc cagtccacca tattgaatct caagctcttt gtttcgtgct
    16501 gttcgaatag cctgttttgt tgacttggaa agtttatctt cttcaaaatt ttccttgtat
    16561 attttcgcct gaatacgagg ttgaatggtg tctcccattt cctccgtttt tcctgaccac
    16621 cttactccca tttgttgcaa actatcaata atagccagat tttcaggaaa ttctgtcttt
    16681 tcctgattga ttaaactttg agataggcaa atacttgggt caaaagtcac aaaaaccgct
    16741 ctcttactgc gagcatagga cttaatagac tgaatgacaa aattcaagag ttctttatcc
    16801 ccataatcca atataggtcc tcttgggatg taaaacattt tatagcctag cggaagagtt
    16861 ctaatcaaaa tactagctgt cgccagtaat ttttcttccc tgtaaacacc aaacttctca
    16921 tgttgccaat tagacttaac ttcctcccaa gcactacttt gtaatacatt ggctaattca
    16981 tgttctttga caaactgatc atattctaat gtgggaatgc caatttgata acggtacatt
    17041 tcctactctc tttcctccag tattttatta ctattctact actttcgttt gaaaagtcta
    17101 gtgaaaacat attttatttt agttctactc cccctatgct gaagttcaaa ctaagtcagt
    17161 ctctcttcta atttgaaatc aattggtagg gttgttaaaa aaacttccaa ttgtttttcc
    17221 cagtagtacc actcgtgagt tccagcgcta tggctatagg tcacatcaaa acctagtttt
    17281 ttgagatttt tcactgcgag attattggct tcgtacaaga aatcctgttc gccacaccac
    17341 gcccaaagtt tggtcttttt atccgatttt ttagccagac tttcaagaga atagggacta
    17401 gttgtccagt ctttaatctc tccaaaaaca cctctccagt aggctggact tcccagattt
    17461 tgactttcag gagaaaagtt ttgaaagctg agggcacctg aaaagctagc tgcatgagaa
    17521 aaacgatttg tcgcaagagc cagtttgaag cagccgtagc ctcccataga aagaccagcg
    17581 ataaaggtct tttcacgctt gctagtcata ttagggaaga agcgtttcag aacctgtggc
    17641 aattcctctg ctagagccgt gtagtagtca aaaccatact gggtatcggt gtaccaacca
    17701 ttgctggtat tgggcataac aacgatgaga ttagttcctc gaagcaagcg ttctacattg
    17761 gtccgcttaa gccaactatt atgatttcca gacatcccgt gcaaaaggta caagacggga
    17821 atatcttcac actctggttc ttccactcga ttggcatcag ggtagaggac attcaccccc
    17881 cactccatat ccaatacttg tgagtaatac tcgattttca ttactgccat gattttctcc
    17941 ttctattttt ctataagaaa aagccgaaac tcgactttct ctctgtttat ttcaacgatt
    18001 attttgcttc catgactact ggtaaaatag ctggacgacg cttggtttgg tcaaagagat
    18061 acttggtcaa attatctcga accttccctt taagatctgc ccagtcaaag tcatctcctt
    18121 gaagatactc ttctaccgtt tggttaatca attctgaact ttcacggaga atatcgcgac
    18181 tcttcttgag ataaacaaat ccgcgcgtat gaacacgagc cctagccaca attttcttct
    18241 cacgacggtt gactgtaata gccacgatga aaattccatc ctctgacaag accttacggt
    18301 cacgaagaac aacatttcca acatcaccaa tggcattccc atcaatcaag atatctcctg
    18361 ctgaaaccga tccagctgga acaaagtctc cattctcgta agccatggtc gtcccctttt
    18421 taggaatgaa gatgtgttct ggcaacatcc caactgccat ggcagcctta gcgtgagcat
    18481 ccaactcacg atactcccct tggacaggga agaggtactt aggttgcaaa agattgatca
    18541 tcagctgcaa atcacgcaca tttccgtgcc ctgatacatg taaactttgg gtaatcaatt
    18601 tgacaacccc acctgcctga taaatcatat tttccacacg cgcaacaaag gcttctttag
    18661 caatagacgg agccgtagca atatagacca ggtccccatc cttgatttct acataacgat
    18721 ggcgaccaat cgacatctta cgaagtccat tgataggttc acccatacga cctgtctcaa
    18781 gaataatcaa ctcatggtct tcaaagcgag acatatcttt aggcttaatc aagagaattt
    18841 cgttggctaa agacaacttc ttaagacgaa tcgctgtgcg gacgatattt tcaatatcaa
    18901 atcctgtcaa gacgatacgt cgacctgttt tatccgcagc gtcaaaaatc tgctgaatac
    18961 gagaaagatt actggaaaca gctgcaacga tgatacgacc ttcccagtca gcaatagttt
    19021 gggtaatttc atccctaact tcactttcac tagccacctg aatattgctg tctgcattgg
    19081 ccgaatcact gaggagagcc aggacgccgt cacgaccaat ctctgccaaa cgagcaaaat
    19141 cagttgcata agattcacta gccgtttggt caaatttgaa gtcacctgta taaacgatgc
    19201 ttccttccga tgtcttcaag acaattccca gactctctgg aacggagtaa gtcgtaggga
    19261 agaaggaaac cactgtccca ccaaaatcaa tctccgtatt ctcatcaatg acatggaaat
    19321 cattaaattt cttaacggca tcatttcctt tgacaaagag ctttgccaac tcaatggtca
    19381 actcagaccc aaatacagga actttagcct ctgccaagag ataaggtaga gcaccaatgg
    19441 catccgcatg cccgtgggtc aagaaaaccc cagcaatacg gtcgctattt tcaaaaaggt
    19501 aatccatgtt tggaatcacc acatcgaccc ctaattgttc attttcagga tattttaacc
    19561 ctacattcaa aacaaaaatg gactctccaa tttcagcaat gtacatattt tttccattct
    19621 cacgcacacc accaagtgtt gttaaactga tattactcat ttttcctcca aaatcttagt
    19681 ttatcttgat tatagggcaa ctctaccctc ttattctaaa agttctaata ctttcagccg
    19741 aatcttttcc taccattata ccattttttt gatgattttc aaaatgaagg tctgttttca
    19801 aaaaagagtt gatttcccaa ctctttccta acttctactc tttttccatc aaaaaatcat
    19861 aaatttcttg caccgtaccc agcgccatca tttcttggtc tttaacggtt tgtttgagat
    19921 tttggtaaat ttgactttct cctatctccc gctttggcgc ctctttattg actgtcatca
    19981 caccatcttt tatcgtcaca aagcctagtt cttcaaatac ttgaatcatc ttgaccagca
    20041 agatttgttg aatattaaga tatgcagcca aatctttcag cttgtagcga atatcaaact
    20101 ctgggaactg gtaaatagtc ttgtacaatt tggcaaactg atctctagtc ccataacctg
    20161 tcagataata ggccttgtca atatcatttt tgaaatagac agcagagaaa tgctgttcct
    20221 gaaaaatggt cttcagctga gtaatatcct ctggaatgtt ttttacgaca atagcttcac
    20281 tagccgcaag atttggcagt tctccaggaa aatccaagac tggaacacct tctggcaaga
    20341 ctgcattttt tccacgaatg ttaaaaagtt gaacaccttc cactcgcgca tccaccatca
    20401 tcaactggag ggcagtttgg ccattccatt ggttgacaga caatttaacc gctaactcta
    20461 gattcttggt ttgagaaaac tctgtcgccc atctgccttg accaaaggct accacttcaa
    20521 aactcgcccc acccttggaa attttcagct ttagatgggc attacctgcc cccatagtac
    20581 gagcactttc gacctgaaaa ttcttgatat aaaaaatagg tttctgatta tccattccaa
    20641 aaggagctaa acgttcaaaa cttttgaccg tttccaagct aagtgcctcc aaatccaact
    20701 cttcatctag gtttaactta ttcttgccac cagcatctgc acctttttca cgaacataat
    20761 cttccaaaac ctgagataaa tctgagagtt gctcaacttc cagcgtcata cccgctgcac
    20821 ctgcatgacc tccaaaggcg atgaagaggt ctcgatgggg atccagagct tcaaaaatat
    20881 cgaccgcttc cacactacga gcactgccct tggcacgacc gtcttctata ttaagaacaa
    20941 tgactgtctg tcccaattct tccaataaac gaccagccac gattcctaga accccaggat
    21001 tccagccttc cttggccaag acctgaacct tcttctcagg atccaccatg gtcttggctt
    21061 cttcatagat agactgaacg atttccttgc gctcttcgtt tttctggtga atcataaggg
    21121 caatctcatg cgcttcctca tcatcaaatc cagtcaacaa atcaatggca ggattgggat
    21181 catccaagcg acccaaggca ttcaaacgag gagcaatctg gaaaccaacc gtttcttctg
    21241 ttacttcgtt ggcagcaatc ccagccatgt ccagcatttc ttgcagacca atgcgctggg
    21301 tatgacccaa catttccaga ccatattgaa ctaagatacg attttcatcc gtcagactca
    21361 ccatatctgc aatagttcca atagcgacca aatcaagcaa ttccacttgc acttcttcta
    21421 acagggcaca agccaacttg aaagcaactc cacaaccagc caaatattta aaaggataat
    21481 ccgcatctgg atgttcagga tggacaatag cataagcatc tggcagggtt tcaggcatgg
    21541 aatgatggtc tgtcacaatg acatctactc ccatagactg agccaatgca atagcctcat
    21601 gaccagcaac cccattgtcc accgtcacaa tcaaggaaat tccttcttgc tcgataaagt
    21661 atttataaac actagcatta gggccatagc catcggtaaa acgatttggc aggtaaactc
    21721 ggcactccgc accaagttgt tccaaacttt ccttcacaat agaagccgaa gtcatgccat
    21781 ccgcatcgta gtctccataa acgagaatat tttccctttc ttcaatagcc tgacgaatcc
    21841 gctccactgc cttgtccata tcatggagca gataagcatc atgtaagtcc tccaaggaag
    21901 gttctaaaaa cttcttcaga ctttcttggt cctgaatccc tctctcaaac aataaccgag
    21961 ccacctcagg acccagtcca gccttcttgg ctatctttgt aaaatccgca tcttctacct
    22021 gcagggcaaa ctgccattca taagtaggtg ttatcaaaaa gacatccact ccttctaaga
    22081 attctattgc ttcattataa catgatttag acgttttctc tatccagatt gcttttttat
    22141 aacatttcat agtatattga aactagaata gtacacctct acttctaaaa tattgttaga
    22201 aatcgatttg actgtcccga tcgatttttc ctgttcttat ttcactatag tgaatttttt
    22261 cagatatggt ttgacaagaa cattctttta ttgcagaatt gtgttataaa atctaacata
    22321 aaggagttct ctcatggctt tagtagaatt taaaaacgtc gaaaaatatt acggagacta
    22381 ccacgcactc cgcaacatca atctccgttt tgaaaaagga caagttgttg tcctgcttgg
    22441 accttctggc tctgggaagt ccactcttat ccgtacgatc aatggtttag aggctgttga
    22501 caaaggaagt ctcctagtca atgggcacca agttgctggt gccagccaga aagatttggt
    22561 acctcttcgc aaggaagtcg gcatggtttt tcaacatttt aacctttatc cacacaaaac
    22621 agtgttagaa aacgtgacac ttgcacccat taaagttcta ggaattgata aaaaagaagc
    22681 tgaaaaaacc gccaaaaaat atctggaatt tgtaaatatg tgggacaaga aagattccta
    22741 tcccgccatg ctatctggtg gacaaaaaca gcggatcgcc atcgctcgtg gtcttgctat
    22801 gcatccggaa ctcctcctct ttgatgaacc aacatctgct cttgatcctg agactatcgg
    22861 agatgttcta gcagttatgc agaaactggc gcgtgatggg atgaacatga tcatcgttac
    22921 ccacgaaatg ggctttgctc gagaggttgc ggaccgcatt atctttatgg ccgacggaga
    22981 agttttagta gatacgacag atgtcgataa cttttttgac aatccaagcg aacctcgtgc
    23041 ccaacaattc ctcagcaaaa ttatcaacca cgaaagtgac aaagtcaaat aaggaggcgc
    23101 ctatgaaaaa aaaattcttt ttatcagcat tattgattag ccttttcggc cttgctgctg
    23161 ccaaaccagt ccaggctgat acaagtatcg cagacattca aaaaagaggc gaactggttg
    23221 tcggtgtcaa acaagacgtt cccaattttg gttacaaaga tcccaagacc ggtacttatt
    23281 ctggtatcga aaccgacttg gccaagatgg tagctgatga actcaaggtc aagattcgct
    23341 atgtgccggt tacagcacaa acccgcggcc ccctcctaga caatgaacag ggcgatatgg
    23401 atatcgcgac ctttaccatc acggacgaac gcaaaaaact ctacaacttt accagtccct
    23461 actacacaga cgcttctgga tttttggtca ataaatctgc caaaatcaaa aagattgagg
    23521 acctaaacgg caaaaccatc ggagtcgccc aaggttctat cacccaacgc ctgattactg
    23581 aactgggtaa aaagaaaggt ctgaagttta aattcgtcga acttggttcc tacccagaat
    23641 tgattacttc ccttcacgct catcgtatcg atgccttttc cgttgaccgc tctattctat
    23701 ctggctacac tagtaaacgg acagcactac tagatgatag tttcaagcca tctgactacg
    23761 gtattgttac caagaaatca aatacagagt tcaacgacta tcttgataac ttggttacta
    23821 aatggagcaa ggatggtagt ttgcagaaac tttatgatcg ttacaagctc aaaccatcta
    23881 gccatactgc agattaagga ggacacccca tgacagattt atcatcttgg acagcctatt
    23941 ttcaggattt tggacaattt ttcaatggtt tcctcttcac ccttgcccta gcgattggat
    24001 cctttatcct cgccatggtc ttaggaatct tctttggtgc catgtcaacc agtaaacgtc
    24061 caattttacg cattttagct cgcatctttg tggaatttta ccaaaacact cccctcttgg
    24121 tgcagtttgt tattgttttt tatggcctac ctcttatcag tgaccatact atcatgattc
    24181 cgatttattg gacagctgtt ctctgcgtgg gactctatca cggcgcttat atcgctgagg
    24241 ttattcgttc agggattcag tctattccta gtggtcagat ggaggccgcc ttatcgcaag
    24301 gttttaccta tatcagtgcc atgcgcttga ttatcttgcc tcagaccttc cgcatcattc
    24361 tccctccatt gaccaaccaa attgttaacc tcatcaagaa cacctctact gtagctatca
    24421 tctctggagt agacttgatg tttgtgacta agtcttggtc ggctctcaac ggaaactata
    24481 tcccagcctt tttaggtgct gctcttctct actttgccct atgcttccct gttgcccagt
    24541 ttggtcgcaa gatggagcaa gccaacaaaa aagcctattc actttaggag gttactatgg
    24601 aatctatttt agaagtttta accccagata acctagtctt tatctttaaa ggatttggct
    24661 tgaccctcta tatttctctg attgccatca tcctctctac tatcatcggt acggtgctag
    24721 ctgtcatgag aaatggcaaa aattctgtct tgcgaatcat ctccagtatt tatatcgagt
    24781 ttgtgcgcaa cgttcccaac cttctctgga tttttactat ctttttggtg ttcaaaatga
    24841 aatccacacc agcaggtatt acagccttta ctctctttac atcagcagcc ttggctgaga
    24901 ttattcgagg cggtctcaat gccgtagaca agggacaata cgaagcagga atgtcacaag
    24961 gcttcacctc agcccaaatc ctctactaca tcattctccc acaagccatc cgcaaaatgc
    25021 taccagccat catttctcag tttgttaccg tgattaagga taccagtctc ctctactctg
    25081 ttatcgccct acaagaactc tttggagcca gccaaattct catgggccgt tatttcgaac
    25141 cagagcaggt cttcagtctt tacatcctga ttgccctcat ctacttcagc tttaacctag
    25201 caatttctag cctgtctcat atgctagcca aacgttggca acaagccgca gaataatact
    25261 cttcgaaaat ctcttcaaac cacgtcagct tcaccttgcc gtatatatgt tactgacttc
    25321 gtcagttcta tccacaacct caaaacggtg ttttgagcag cctgcgggct agcttcctag
    25381 tttgctcttt gattttcatt gagtataaac agccactctc caattcaatt ggagagtttt
    25441 ttgatgagag tagatattta tagacctcaa tttgacacca tacattttct atgataaaat
    25501 gtaacaaatt catttacaac aaatcgaaat ctaaatgaaa tggaattttc tatgaaatca
    25561 gtcaaaggac tactctttat catagctagt tttatcttga ctcttttgac ttggatgaac
    25621 acttctcccc aattcatgat tccaggacta gctttaacaa gcctatctct gacttttatc
    25681 ctagccactc gtctcccact actagaaagc tggtttcacg gtttggagaa ggtctacacc
    25741 gtccacaaat tcacagcctt tctctccatc atcctactaa tctttcataa ctttagtatg
    25801 ggcggtttgt ggggctctcg cttagctgct cagtttggca atcttgccat ctatatcttt
    25861 gccagcatca tccttgtcgc ctatttaggc aaatacatcc aatacgaagc ttggcgatgg
    25921 attcaccgct tggtttacct agcctatatt ttaggactct ttcacatcta catgataatg
    25981 ggcaatcgtc tccttacatt taatcttcta agttttcttg ttggtagcta tgccctttta
    26041 ggcttactag ctggttttta tatcattttt ctatatcaaa agatttcctt cccctatcta
    26101 gggaaaatta cccatctcaa acgcttaaat cacgatacta gagaaattca aatccatctt
    26161 agcagacctt tcaactatca atcaggacaa tttgcctttc taaagatttt ccaagaaggc
    26221 tttgaaagtg ctccgcatcc cttttctatc tcaggaggtc atggtcaaac tctttacttt
    26281 actgttaaaa attcaggcga ccataccaat aatatctatg ataatcttca agccggcagc
    26341 aaagtaaccc tagacagagc ttacggacac atgatcatag aagaaggacg agaaaatcag
    26401 gtttggattg ctggaggtat tgggatcacc cccttcatct cttacatccg tgaacatcct
    26461 attttagata aacaggttca cttctactat agcttccgtg gagatgaaaa tgcagtctac
    26521 ctagatttac tccgtaacta tgctcagaaa aatcctaatt ttgaactcca tctaatcgac
    26581 agtacgaaag acggctatct taattttgaa caaaaagaag tgcccgaaca tgcaaccgtc
    26641 tatatgtgtg gtcctatttc tatgatgaag gcacttgcca aacagattaa gaaacaaaat
    26701 ccaaaaacag agcttattta cgaaggattc aagttcaaat aagtaatcat actctcctgg
    26761 gatttcccag gagagttttt tatagccaaa tgaaataaga ccggaacgat ggaattttgg
    26821 cattcaaatc aattgataag aatattttat agtggagtga aataggatac gaacaaattg
    26881 attaggaaaa tcaaatgaat ttatagaaat cttttagcag ttatgttgtc ctattctagt
    26941 ttcaaaacgc tatagaagca gcattgtact agtctagatt cagtttacta tactaaaacg
    27001 agtagcttga aatcaaaaaa cccaccctca caggcaggtt ttatctgtat tattcagcta
    27061 gattatgctt taccttctga accgaatacg tcgatacgtt cttcaaccga tgcttggata
    27121 gcttttacac cgtcagccaa gaatttacgt gggtcgaaga gttttttctt gtcgtattct
    27181 gcttcgtttg cttcgtagtc acgagcaaat ttacgagttg cgttagcgaa tgcgatttgg
    27241 cattctgtgt taacgttaac tttggcaaca ccaagtttga tagctgcttg gatttgctca
    27301 tcaggaatac ctgatccacc gtgcaatacg attgggaatc ctggaagagc ttctgtcaat
    27361 ttttgcaagt ggtcaaggtc aagaccttcc cagtttactg ggtaagggcc gtggatgtta
    27421 ccgataccag ctgccaagaa gtcgatacca gtttcaacca ttgctttagc gtcttcgatt
    27481 ggagccaatt cacctttacc gatgattccg tcttcttcac caccgatagt accaacttca
    27541 gcttctactg agataccttt agcgtgtgct ttttcaacaa cttctttagc caatttaagg
    27601 ttttcttcaa ctggaaggtg tgaaccgtca aacatgattg aagtataacc aacttcgata
    27661 cactcaagtg catcttcgta gtgaccgtgg tcaaggtgga tagctactgg tacagtgata
    27721 cccattgatt caacaaggtt agcgatcaag ttgcgagcaa ctttgtaacc acccatgtat
    27781 ttagcagcac ccattgaagt ttggatcaaa actggagctt ttttagcttc tgctgcgcgc
    27841 aagatagctt gagtccactc aaggttgttt gtgttaaatc caccaactgc ataaccgttg
    27901 tcacgggctg cttggacaaa tttttctgct gaaacgattg ccattttatc aggcctcctg
    27961 tatattttta tgggtcatcc catttacatt gttcatttta tcactttttg ccaaaaaaat
    28021 ctagtttttc ccgcagtttc gattgatttt cttctaactc catctatgta aaccctttct
    28081 ctccctagtc ttggacgact tttggaaaat ctataaagaa ggttaaacga ttctcctcca
    28141 tctcgaaacg ataagctaat ttttcatgtt ctaatagact cttaaccaca aagagcccca
    28201 taccagaccc cttgaccttg cgactggcat tgtcagaaaa agactgggct agtttttctt
    28261 gttcctctga gctacagcta ttttcgataa aaagttctcc ttctctttct ccaattcgaa
    28321 ctaagccacc tggaacagag tgcttaatgg cattgctgat gagattagaa agaatcaact
    28381 tcataactga tgggtttaga taagcctgct gatgggtcaa actattgtct atctggagct
    28441 ctctttcctt ggctagcaag gcataatctt tgaccagatt ttgcgtcatc tggaggaggt
    28501 caattgtttc cctatcatct cgcaattcct gcacagaaga gagggaaagt atctgcagaa
    28561 catggtgatt gagttcatcc acaatcccca aggcaactcc cagatactgg tctctatcct
    28621 tataacgacc gatattctct ctcatatttt cgattaggat tttcaaacta gccagcggtg
    28681 ttttcaattc atgagaagct cctcgtagga attcgacctt catcttctcc agctggagaa
    28741 tggcttcatt cttttcatgc aagtccgcaa taacagtcaa gagatgctgg tagaggctat
    28801 tgatttgttc cttgagatta cctatctcat ccttagaatc cacgcgcaat cgcacttggg
    28861 aatccaggtc catcatccga cgggtcaccc gcttgatttc caaaatcggt gcaacaatag
    28921 tccgagcgta gatgtaggcc accaagaggg aaatcagaaa ggaggccagc aaggtatagg
    28981 gaagaaactg gagactgatt tgctccgctt ccttttgtaa atccatggaa gctagaaact
    29041 ggagaatcat agtaccaccg tcttgcgttt tcacctcgcg ctcctcaata aagagagagg
    29101 ttgtctggcg gtctgtgtcc agaggaagac tgtccttgac ttctaacttg tcctcggtca
    29161 tctcaccttt gacggtcccc ttgatatcac tagtctggga atacaagtct aacacttgct
    29221 cgatactctg cctatctttc ccttctaggg actgggcaat ggctgttgcc ttttgaccaa
    29281 tggtttcctg acgatgactc agataagtcg aaggaaaaag aaaataaata gctaaatgaa
    29341 ggcagataac cagaacacta aatatcgaga aggtatagat aaatatcttt gcaaataaac
    29401 ctgttcgttt cattttcgct ccaatttata accaacattg cgcacagtga ggatacaatc
    29461 caagtctagc tttttccgca attccttgat ataaacatca ataacacggt caaagggaac
    29521 ctcatctgtc gctttccaga cggcatcgat aatctgagat cgagtcaagg cccggccttc
    29581 atttttcact agatagtcca gaatttccaa ctctttggca ttgataggca cttcttgacc
    29641 tgcgatgctt gcactgtagc tttcaaagtc caccttggta tccttgtaag aaaagattcg
    29701 tcctgtatcg tagtagcgct tgaaaatcgc gtccaccctc acttttaaaa gggagaggga
    29761 gaaaggtttt tccagatagc catctgccaa agaggcaaag gcactcatct tgtattcctc
    29821 atcctgaaaa gctgtcaaca tcaagacagg aacctgactg gttttacgaa tctcagctag
    29881 gacttctaag ccgttgagct tgggcatctg gatatccagt aaaaccaggg ccacctcata
    29941 gctagaaaat tgctccagag cttcctgacc gtccgctgcc tcaatagttt catagccaca
    30001 atccgtcaaa taatcactga ccccctcacg gatcatctct tcatcttcta caattaaaat
    30061 tttcatactt taactgctct ctatttttta tttttcttag aataaatacc tactctattt
    30121 tctattatag tctcttgctg gccttttgtc tgtaagtaac tgaccactag ataaaacgtt
    30181 gtgaaattcc tttctcataa attccataac tttagtatat tatatttaag cactaaagta
    30241 caaagaaagc aactgaaagc aatgattttc accactgctt tcagatttat tttgaattgt
    30301 taaatagcca ttcctatcca ctattcttga atagaaacac aagatgcaat ctttattcca
    30361 gactcatttt ttcaaattta ttcaccatcc agcaagagct cttttggttg ttttctaagg
    30421 agattgcttg aagcaagcgc cataacgaga accactagaa ccaaggcaag gacaaaaatg
    30481 atgataaagt ctgatgtctg aatagaaatg tctaggctcg acaaggtctt gctaaagcca
    30541 tctacttctg caccaccacc aaggttagag gcttgagccg ccttactagc ctgtttggca
    30601 acacctgaag tcacattggc aaggacagtg tttccaattg cacgggcagt gtaattagct
    30661 aggaagtaag cagaaactag agcagggata gcaatcaaga tagattcggt gatgaattga
    30721 cccaagatac ttgcctgctt gaggccgata gagaggagaa ttcccacttc cttgcgacgg
    30781 gcgctgatcc aaaggctgag caagagggca aggaggagaa ctgagaagct caagctaccc
    30841 cagaagagga ggttggccat cttgtacata ccagagatag attgctcaag agctgggtag
    30901 ttagaggagc tcttgacgag tgtgtagctc ttccagttga taccactgat gccattcaac
    30961 tctttcataa catcatccaa gttcttgtct gctgttacaa agaaggttgc gtccccataa
    31021 atggctgtgt cttctgtgta tccataaagt tttgcagcag tgtgaatgtc tgtaatagct
    31081 gtgttttcgt aaagttcttg tgagtaggtt actgctgact tattatgacc atcaaagagt
    31141 cccttgattg tcacttcaac tgtttccttg gctccttttt cattatctgc atcgtagata
    31201 ttagagtcca gtttaacctt gtcccctact ttccagccgt gtttggctgc caagtccttg
    31261 tgcaagagga ttttatcctt gtcgtcgttg gttaagtgct ctccttcgac tagtttataa
    31321 gaaccagaga caaacttgtc ttctttagag gagtcattga cacctgtaat catcaagcta
    31381 cttccaaaac gtttggcacg atcagcagtg agattcttct tggtttctgg cgtttcaatc
    31441 aggtcatatc cagtcaaatc tccgatagcg ttgatacgtt tgacataaga ctcaatggcc
    31501 ttgttttcgg tgattttttt gatgtcttca cccttgatat tcccagcacc gcgaggcgtt
    31561 ccttggttga cgcgacgatt gatttgcatg gagaagctat tggtgatatt tttaaaggtc
    31621 tcctgagaag ccttggcagt agctcccttg attgacaagc cgaccaaact caagctcgcc
    31681 atgaggagaa taatcaggaa gatgacaatc gatttgaaaa acttccttgt aacataggca
    31741 aatgcgttgt gtaacataga ttccctttct agattttgtt ttaatcattc tattaaagta
    31801 agctcaaatt atttactagt attgcgcgtt tcagtcagtt tcttatcctt taattcaagt
    31861 gtaatatctg acgcttgtgc cacttcttta ctgtgagtta cgacaatcac acatttacct
    31921 gttttctggg caagtgattt gagtagttcg acaatatctc cagcagtttt aggatccaga
    31981 tttcctgttg gctcatcagc tagaataact ggagcttctg agaccaaact gcgagcaatg
    32041 gcaacacgtt gctgttgacc acctgataac tggagaacat tccgcttgat ctggctttca
    32101 tccaaaccaa gctcaagaag tgtattcttg cttgcctttt tgttgaccaa tcggatattt
    32161 tccagcggag aaagataatc tatcaagtta taattttgaa agaccaggga aatatggtgc
    32221 atgcgatggt aagaatagcc cttcttacga atatcctctc cttgaaaaag gatagaacct
    32281 tcaacaggac tatctagacc agcaagtagg gacaagagtg tggattttcc tgctcctgac
    32341 tccccaataa tactgtaaaa ttttccgggt tcaaaattat aattgatctg atataggact
    32401 gcttcagcag tattcttata acggtaggta acatcttgta attgtaataa agtcatgatt
    32461 tctccttctt aactaataga tgataaaatt tctttcggtg attttctaaa taagaatagg
    32521 aaacaaaggg ctacagataa gcaactaagc agaactagaa aaacatagga ttctgcaaaa
    32581 gataagatgc tagttgataa actgcttgct ttggctagtg tatcttgtaa gcttgcctga
    32641 tctccacttg ctagtagagt ttggagtagg taagttgtga ttccgtttcc tgcaacaaat
    32701 gctggaagca aagctccaag agataccaaa actacctcta aacagaattg taggaaaatc
    32761 gagctcttgc cttttccaag tgcaagtaaa atccccactt catagacccg ttctctcaac
    32821 cagagagaca aaaccagaat taaggctcca gctcctgcta tcaacatccc ataaaggaag
    32881 atggtcagga aggtttggaa agttgcaact gagtctttga tttgttcaaa agccttgttt
    32941 tccttttcga cttggtagcc ttgattttcc aaggccaagt tttctacctg cttcatgagt
    33001 ccgtccattt ccttaggatt ttctacatag aagcgtgctg cactgacttg agcttcacta
    33061 ttgcccaaaa gggtttggct actttcatag tctgtaaaga cttgattttc actgaagtca
    33121 gaagacaagc ctgtgaattt ctcttgtttt ttaccagaaa agatgccgat aatctcaaac
    33181 tctactgttt gtccttttcc agattcagac tgaccagcat ccaagccaat cttgtcatga
    33241 agtgaaagac cgttcttctt agccaattct tcgtggataa ggattttctt ggaattccct
    33301 ttttgaaggt gtcgcccttc ttttagattg aaagccgaac tggtaaaggt tacatccttg
    33361 gatgaatcct caagagccgt taagctaacc aagttattgt ctgcagctga taaatcatca
    33421 cgctccacgc tctgctcgcc agtcactgct tccttgtctt ttagttttgc gaccgtctca
    33481 agttcaggag agacattttc cagcccctta atcttgctta cagatgctag gtctgacaac
    33541 ttgaatgtct gaccattctc tatcttctta atagaaaaag atgtattgag tgatttataa
    33601 agattgcttt ctactgtttt gttggacttc atcagagtca aacaggctga aattccggcc
    33661 aataagacca ataaaatcag aaataaaata aaacttctca gtcgctttct gctgacataa
    33721 gcccaagatc tttggattgg attcatttgt cacctccata tttgtaagac tattataaaa
    33781 cccaaatatg aaatgtttat gaaatacgaa aaaaaatatc gagtagggga taatctctag
    33841 cccctctcac accaccgtac gtgccgttcg gcatacggcg gttcaactaa cttttaacgc
    33901 atgtcgttca aggtaataat ccaaacacga aaccagtcca cgtttttcaa gggctggttt
    33961 tgatatagca cgtttaagta ccgacttctg agctactaat tgatagtggt cgccccagcc
    34021 agatacctta tctgctatcc atttaggaac ccctaactta agcaatcccc ataatcgtct
    34081 cgatttcttc ttccattgct tccagataat cactcgtagg cgagtacgca agcgctcatc
    34141 tatgctagtg actatacttt tcatatttat aattcattcc tttcgtttca ctcaaggcac
    34201 aacacagaat gaaaaagtgt tgtgctcttt attttgtttt ataataatag ttagaaagcc
    34261 tatcactact acaaatcacg gggaggtgaa taagtgagtg gtacagccac tacctcgcat
    34321 attttgtcac atcatttaac ggtacataat aagttgtacc atctgaataa gttgctacaa
    34381 tatcatttgc atgctctcct tcacctttag caaaggttgg agctcctact ggataatttt
    34441 tatttgcctc tttcaatttt tcaataatgg catttttttc tgtatctttt atattatcag
    34501 gatttttcac taagattttg tctggatatg tcggtttagc agaaacaatt tttactgtta
    34561 tttctttttt attcgaagca cttgtccagt ttccagcatt atctttagca tttaatttta
    34621 cagtaattcc tgaactaaga acttcagtag caggttgatt atcaacatta ttcaacttta
    34681 atttcaaaag agctgttgca tcagacgttt tatcaatcgt tgtatataat gataaattgt
    34741 tattataacc agtttcttca tatttagctg tttgtgagct acttgaaaca gaactgaaat
    34801 tatgcccact acctccctga ttatcttcaa tgcttacgtc taaatgaact tccccactat
    34861 tatttggctt agcaacaact gttatagtaa aataacataa aatttgcata aatagattag
    34921 ggaaatcaaa gcaacttcta ggaatgtttt agcagtcaca gtgtactttc ccagcatcaa
    34981 tccactataa ctctgcacat aaaaatggag aagatggcca tcctcttctc caaatattaa
    35041 cttctttaca aaccaactat agttgacaaa gaacctaaaa tcaattgata acacaaggtc
    35101 aggtcggtca actctttcaa ctgaagccct gtcaactctt cccatttatc aatcttgtat
    35161 tggagagaat tgcggtgcag atagagttgc tgggctgttt tagtgagaac agcactattt
    35221 tcccaaagag agagaatgat ttcctgaatc tgatcttgat ccaaaatcat ctggtgtaga
    35281 cattctttaa ttggcttcaa gtccacgagt ctttctccca tactccaaag atagagctga
    35341 gaaaaagtat gaacaccttg gtgaccctga cgccaccatg tcttgaacaa atcccgctca
    35401 gctttgatta agtctgatag ggcttgatgt cctgtctgag accaaacctg acccaacatg
    35461 atagaaagac gaagtccaaa gtcatactca accgcttcaa tcgtatcact caaaatatct
    35521 cttacagaag tgtatttgtc ttgttgaagc acgaaaacat aatcctgagc tccgacctgt
    35581 agcactgtct gacaattcgg aaaaagagtc cgcatcatat ctagccaaga agtcagattt
    35641 tcctgctgaa aataagaaag atggcaataa accaactgaa tctttttaaa aacttgcggt
    35701 gcctgtccct tgccctcaac cagataggaa taccatgggt ttagcgaacg agcctgctcc
    35761 tgctgggtca aaagggcaac caactgcttt tcacgctcgc tgagcccagc ttcctccagc
    35821 aaaatccact gctgagaagc taaaggaagc gtgagatagc cctctttctc tactggttgg
    35881 tctgaaatcc gagcctcagg aaaccagtct tgtagttctt ttgccctcat gttctagccc
    35941 tccacttttt ggatgcacca tgaaaccaaa ctctcaagac gttccagatt ctcagtcata
    36001 tggagatagc ccataactgc ttcaaatccc gtggacatac gataagtcac gacatctgca
    36061 tttttagcct ttgtgtgact attggtattg cggccacgtt tgtagatttc ttcttctttt
    36121 tccgttagga tctgctcctc caacatgagg gaaatcaggc gagcttgagc cttggctgac
    36181 acgtacttgg tcgcctcttg gtggagttta ttgggcttgg tcataccttt gaggatgagg
    36241 tggcggcgaa tatacataga atacaccgca tctccctcaa aggctagcgc aatcccgtta
    36301 atgagattga catcaatcac gtgtccacct cactccatcc ttggtatcaa ggagcttaat
    36361 tccttgagta accaattggt cacggatttg gtctgctgtc gcaaagtcac gattggcacg
    36421 cgcctcttgg cgtttttgaa tcaagtcttc aatctctgca tccaaaactt cctcaacaaa
    36481 gacaattcca aaaatttcta acatatctgc aagagcttgc ttgacacttg catcatagtt
    36541 ccctgagttg atccatttgg tcatttcaaa gacaactgtg ataccgttgg cagcattaaa
    36601 atcttcatcc atagctgcta caaacttatc tttaaagttt tgtaactctt gggcatccac
    36661 gtttcctgta aatggttgtt cgtaagtatt cttcagatac ttgagattgg tctcggcatc
    36721 gcgaactgcc ttttccgtga agttgatagg cttacggtag tgctgggtcg caaagaagaa
    36781 acgaagtact tgcccatcaa gagttttaag ggcatcgtgt accgtaatga agttacccaa
    36841 ggacttagac attttgacat tgtcgatatt gacaaagcca ttgtgcatcc agtagttagc
    36901 aaaagccttg cctgttttag cttcagattg ggcaatttca ttggtgtggt gtggaaactc
    36961 taggtcagct ccaccaccgt ggatatcaat ggtatcacct aaaatctctg tcgacatgac
    37021 tgaacactca atatgccaac ccggacgtcc aggtccccaa ggactatccc aagaaatctc
    37081 acctggtttg gaagatttcc atagagcaaa atctacagga ttttccttac gagccgtttc
    37141 ttcatcggta cgacctgaag cacctagatc caaatcttcc aaggttttat tagccaattt
    37201 agcatagttg tgggattttt ctacacggaa atagacatcc ccttgactct cataggcaaa
    37261 gcctttctcg atcaagtctt ccacaaaacg gatgatgtct gccataaact ccactacacg
    37321 cggatggcga gtcgcaggtt tcacgcctaa ggccgtcaca tcctcacgaa aggcagcgat
    37381 gtacttatcc gcaacctcct gaggcgtgat accttcttcc ctggcacggt tgataatctt
    37441 atcatccaca tctgtaaaat tggaaatata ggcaacctta tacccacggt actcaaaata
    37501 gcgacgaatc gtatcaaaag ctaccgtcga acgggcgttt cccacgtgga tatagttgta
    37561 caccgttggc ccacaaacat acatcttgat cttgccgtcc tcaatcggga caaattctcg
    37621 caaatcacga gacatggtgt catagatttt aatcataaat cataatcaag aaagctgaaa
    37681 tccaagaaca attagtttca tcactaaaag ttcaagtaaa tttcagtccg aatatctcta
    37741 cacttcggaa tcccttgctc ctttctcatt cagataaacc acctgagtct gtttgacaaa
    37801 gccaattttt tcatacaaac gtttggcacc tacattgcta tcttccactg caatctgaaa
    37861 ttccttgtca ttttgctcaa ttagttggtt gacgagggat tttgctaagt agcttccata
    37921 gcctttccca cgttcaggtt ccgatattgc taaaccgtag aagtaattcg tattagtcga
    37981 taaatctacc gtgcaagtcc caataacctg accgtctttt aacaaaatat ataagcgact
    38041 ttctggatcc ttcagagctt cagcgacata tctatccaca acttctctcg attcatgttc
    38101 ctctgaaaat gcctgaaatt ttaattgact aatttgatcc tgatacgaac tatctgctaa
    38161 caaaacttca agatgggaaa catttgctaa cggataaggt cttctatcct tacctaacca
    38221 agtttctgtc tcttcatcct cgattagtcc ccagttactg gcaaagtcag gatgattctc
    38281 taaaaaaata cgttctgtct gaaaagtgac tgaccgaatg gggaaagaag ctgtttctct
    38341 ctcaaaacta gtaaacaatg cacgcgcaat cccctgacgg cgatgacctg gatgaaccag
    38401 tatcgttact tctacatctt ggtcatctgc ataaacagtt aataaaccaa caagttcgcc
    38461 tttttcataa taaaggaaaa aggcgggcat gtttgggtca aaattaagca tgttagagag
    38521 atagggatcg cgataggtac cgtcatagtt ttggcaacag ttaattactt ttttcgcctc
    38581 agatagctcc tcttggctta acttgtttct tgcttgaatc atataggtat cctctacaaa
    38641 ccagacgatc tgtgactggc atctttagcc tgctcgagtt tattgacata atactctcgt
    38701 ttttcttcga cttcgtgaat gacaggctca tctttcttac catgaagacg gacaatcttg
    38761 gccggaatac cgacaaccgt cacgtcacta ggtacatctg ctacgacaac tgctgcagca
    38821 ccgaccttgg cattttcacc aatttccaca ggcccgataa cttgggcatg ggctgatatg
    38881 agggctccct ttcgtacagt cggatggcgt ttgccacagt ctttccctgt tcccccgaga
    38941 gtcactccgt gatagagaag aacgcctttt tcaacaatcg ctgtctctcc aatcaccaga
    39001 ccagaaccat ggtcaataaa aacacctgaa tcaatctggg ctcctggatg aatctcaatc
    39061 tgagtccaaa agcgccaaaa ctgactgtac atacgagcta atagtttgaa gccgtgcttc
    39121 cagagaaaat gcgagagacg gtgggccgcc aaggccttga cacctggata agtcagcaaa
    39181 acctccaaag tggtgcgggc cgctggatca ttttctttta caatatcaat ggtttcgcgc
    39241 caccacccca tacatttctc cttttcttat tctgaatctt ttggtgtttc tgtaaattct
    39301 ttcttaggtt tgtgatcctt ttgatgacgt gggcggtgag ggcgctcaga cttttcacct
    39361 ttttcatcat gctcaggttt tggcggacga ggtagaagag ccttcataga ggcatcgata
    39421 cggccttttt catcaatttt gataacctta acatcaactt catccccgat ttctaccaaa
    39481 tcctctacac gattggtacg agtccaagcc atctcagaga tatgaacaag ggcatctgtc
    39541 ttatcaaaga ggttaacaaa ggcaccaaat ttctcgatac gaacgacttt agcacggtaa
    39601 acttcatcca ctttggcttc acgaaccaaa ccagcaataa tttctttggc acggttaata
    39661 gcatcttggt cactagagta gatagacaca tttccttctt cgtctatatc aatcttaaca
    39721 cctgtttcag cgataatctt gtcgatggtt tctccaccct taccgatgac aatcttaatc
    39781 ttgtccacat caatcttgat cgtatcaatt ttcggagcag ttggagccaa ttctggacga
    39841 acttctggaa tggttgcttc aatgacatca aggatttcaa aacgcgcttt cttggcttga
    39901 gcaagagcct ccgtcaagat ttctgcagta atcccttgaa tcttgatatc catttgaagg
    39961 gctgtaatcc catcacgagt acctgcaacc ttgaagtcca tatctccaaa gtgatcttcc
    40021 aaaccttgga tatctgtcaa tactgtgtag ttatttccat ctgagataag tcccatagca
    40081 ataccagcta ctggcgcctt gattggcaca ccaccagcca taagggcaag agttcccgca
    40141 cagatagaag cttgagatga agaaccgttt gattccaaaa cttctgctac tagacggata
    40201 gcgtatggga attcttccaa gcttggcaag acttgagcaa gagcacgctc accaagggca
    40261 ccgtgaccga tttcacgacg acctggcgca ccgtaacgac ctgtttcccc tacagaatat
    40321 tgagggaagt tatagtggtg cataaagcgt ttcttgtact ccagatccaa accatcaatg
    40381 atttgagttt ctcccatcgg agccaaggtc aagacagaaa gggcttgcgt ttgtccacga
    40441 gtgaagagac ctgaaccgtg cacacgagga aggaagtcga caaccgcatc caaaggacgg
    40501 atttcatcga ccttacgacc atcaggacgc accttgtctt ctgtaattaa acgtcgcact
    40561 tctgcgtgtt ccatttgttc caagatttca gccacatcac gcataatacg gtcaaattct
    40621 tcgtggtccg catatttttc ttcgtaaacg gcagtcactt ggtctttcac tacttgagtc
    40681 gcagcttcac gggccaattt ctcttctact tgaactgcct tttggaggtc actgttgtag
    40741 gctgcaatga tttcagcttg caattcagca tccacgtgaa gcaattccac ttctgctttt
    40801 tctttaccga cagcagcaac gatttcttct tggaaggcaa tcaattcttt gacagcttcg
    40861 tgccctttaa ggagcgcttc caacatgatt tcttctgaca attctttagc accagactct
    40921 accatgttga tagcgtgctt ggttccagct actgtcaatt caagaagaga ttgctctgct
    40981 tgttcttgac ttgggttgat gatgatttgg ccatctacat atcccacttg taccccagca
    41041 attggtccgt caaatggaat atctgaaata gacagtgcca aagatgaacc aaacatagca
    41101 gccattggtg cagacgcatt ttcatcataa gaaagcactg tattgatgac ttggacttca
    41161 ttacggaaac cttccgcaaa cataggacga atcggacggt caatcaaacg cgctgtcaag
    41221 gtcgcatctg ttgaaggacg tccttcacgt ttcataaagc caccaggaaa cttcccagcc
    41281 gcatacattt tttcttcgta gttgacttgg agtgggaaga aatccccagt tgccattttc
    41341 ttagacataa cggcagcagt caagacagtt gactcaccgt aacgtacgac aacagatcca
    41401 tttgcttgct tagcaacctg accagtctct acaattaact cacgacccgc aacagtcgtt
    41461 tgaaacactt gttttgccat tttaatcccc tttggattga tgaaattata cgccttgcct
    41521 acaaagatca agataccaag gacgtcaaaa acaaagtaaa aataggaaac tgacgaagtc
    41581 ttcgatgaag acaagacagt ttatcttttt tacacagctt ttcggccgtg ttcaattaca
    41641 caagatattt tggacggttc ggcttgccga acatttctgt agaaaaatag gaaggtgacg
    41701 tcgcactcga cgagtgctag gaagcttatc ttttttccta agaaatgaga ccaaaattca
    41761 attactcaag atactaagcc gtcaagcaac tcaaaggaaa ataggaaatc gaacgacgga
    41821 gcgactgctc ctagggagat ttatcttttt ccacagagtt ttaggcgagt tcagttttca
    41881 agatataaat cattagaaag gtttaatact aaagtatcta aagctttcac gctaatcgct
    41941 atcgggcgat tagctaaatg ctttactaac tctctcgtca aataacatcg atttgactca
    42001 ctcgtgtcgt taaatcttac agtttaaatg cattgtatta tttaatacct tcatctttgt
    42061 atcaagtacg tacagaatct attttatcat atttttctta aaaagtgagg tctttaccat
    42121 taaaaaggaa ccattcccct cacctgagaa gaatggtttg cttttattat cctagagact
    42181 ggtgattaaa caaggcatgg gttgcttgat ggatgtattt tgctgtatca gcattattca
    42241 tcgtatagag atgcacaccg gcaacatcct gagttaccaa gtccacgatt tggtccactg
    42301 cataggcaag ccctgctgct ctgagcgact cagggtcatg ctcatacttg tctaagatgg
    42361 ctttaaattt gcgtggaaga tggatattct cacaagtctt caagagtcgg agagcctgat
    42421 ttcgattcag aattggcata attcctgcat gaatgggaac atcaatccca gccaagatgc
    42481 acttgtcctg aaaatcatag aagcgctcat tgtcaaagaa gagctgagtt acgaggctcg
    42541 aacagcctgc atccactttc ttcttaagat tttgaatatc tgaaatctga tttggcgaat
    42601 ctggatgccc ttctggatag caagctccaa taatatcaaa gtgaggggtt tgttccttga
    42661 taaactcaat caagtcggtt gcatagcgga aatccttttg tggttccacg tctggaataa
    42721 tatccccacg aagagccaag attttctgca ccccaacttt gtccaagtca gcaatagttt
    42781 cagcaacctt gtccttagtt agataaatag ctggcaagtg ggcaatggtc ggaatcgcca
    42841 aatcattttg gataaagtca gccaaacgaa ccgtcgtttc cttgatatta aatttattat
    42901 tgctggcagt tacactgata aaatggggag ccaactcctg catatcctgc aaggctgaaa
    42961 taatgttatc attacccacg gctgggtttg gagggaacac ttcaaatgag agtgacggtg
    43021 tttggcgtga catatgtaat aaccttttct agttgatttc tttttgaaca accactgtat
    43081 ggagagaaat ccaatcttac aatttctcac gcgcagcttt agctgcttca acaaggcgga
    43141 tcaagctttc ttttgtttct gggataccac gtgttttcaa accacagtca gggttgatcc
    43201 aaactttctt gcttggcact ttagcaagga tggcttcgat tgtgttgtcg atttcgcctt
    43261 catttggtac acgaggtgag tggatatcgt aaaccccagg tcccacttct gtttggaagt
    43321 ttttcgcttt gagttcgtcc aagatttcaa ggtttgaacg gctagcttca aaggaaataa
    43381 cgtctgcatc catgttatcg atagctggga tgatatctgt aaattctgag taacacatgt
    43441 gagtgtggat ttgtgtgtct ggcgctactg ttgagtgtac caagcagaag gcaggaatag
    43501 cccagtcaag gtagtcttcg taccagtcgc tacggcggag tggcaatttt tcacgaagag
    43561 cagcctcgtc gatttggatg attttcacac cagcagcttc aaggtcaagt acttcatcct
    43621 tgatagcaag ggcgatttgg agagttgaat ccttgataga gatgtcttca cgtgggaatg
    43681 accagttaag gatggtaaca ggtccagtca acataccttt aacaggtttg tttgtacgac
    43741 tttgtgcata gctagaccat ttaacagtga tagggttaag acgagtgaca tcaccccaga
    43801 tgattggtgg ttttacccca cgcataccgt atgattgtac ccatccattt ttagagaaga
    43861 ggtatcctga caagttttga ccgaagtact caaccatgtc attacgctca aattcaccgt
    43921 gaacaaggac atcaaagtca atatcttctt gccacttgat ccattcgtca atcgtttcag
    43981 caaggaaagc atcgtactct ttttgagaca attcaccttt acggtaagcc aaacgtttgg
    44041 cacgaacttc ttttgtttga gggaatgaac caatcgttgt tgttggaaga gctggaagtt
    44101 tgaaagcttc ttcttggata gcttcacgtt ctgcaaaggc tggcaaacga gtgtagtctg
    44161 cgtctgtcaa gccagcgata cgcgcacgaa gttcagcatt ttcaccaaca cgctcagtcg
    44221 caaaaagttc tttgttggct gcaagagctt ctgaaccttg accattgcgg atagcatcca
    44281 agtcacggat ttcatccaat ttttcaactg caaaggcaaa gtggttcaag agtgctggtt
    44341 caaattcttc attagcagtt gtaaatggca catgaagaag tgagcaagag cttgtcaaaa
    44401 cgatgttttc agctggaatt tgctcaagaa cagccaagct cttttcgtag ttgttgcgcc
    44461 agatgttttt accattgaca atacctacat agagagtctt gtcagctggg aagccacctt
    44521 taacgagttc aagagttttc ttaccttcaa caaagtcaag accgatagca tctactggta
    44581 agtttacaag gtcagcgtat acgtcacgaa catcaccgaa ataagtttga agcaagactt
    44641 caagaccttt tttgtcagcc aagagtttgt tgtaaaggtt caagaagaga gctttttctt
    44701 cagctgtcaa gtcttttaca agagccgctt catccaattg gatgcgagtc gcaccaagtt
    44761 cagccaattt agcaaaaact tcttggtaag cagccactaa gctatctacg aagtcgtctg
    44821 ctttcacgcc ttcttcaaag tctgacaatt gaaggaaagt gaagggacct acaagaacag
    44881 gacgagtgtt caatccaagt tctttggctt cttggaactc atcgaaaatc ttgtgaccag
    44941 ccaattttac ttgagtgtct ttttcaaatt taggaacgat gtagtggtag ttagtgttga
    45001 accatttctt cattggaagg gcgcgaacgt cccctttttc tccctggtaa ccacgtccca
    45061 aagcgaagta gcgctcaagg tcagacaagt ccaagttttg aacggatgca ggcaccacgt
    45121 tgaaaaggaa agccgcatct aggaagttat catagtgaga aaagtcattt gatggaattt
    45181 cagtgatgcc tttttctttg acaatgttcc agtgtttagc acgcaagtct tttgctgctg
    45241 ctaaaagttc ttcttctgag atttcttttc taaagtattt ttcagttgta aattttaatt
    45301 cacggaattc gcccaaacga gggaaaccga tgattgtagt tgacatgatg tgtcctccaa
    45361 aatttgttgt tgaaactatc ttaacagaaa agaaagcgtc tgtataattg taaaaaatta
    45421 gggtttgata tagtttgaaa ctatatatct gtttcggaca aaagaaaaag acttgaagca
    45481 aacgtctcaa atcctttgta attcttactt tacagctata ttccaattag aatactaaaa
    45541 catgttatta gtaattctta taagtgacta tgacctgtta ttagaaaaga ctataactga
    45601 ttctagtcaa ctttttccct gttcaagtgg gacgattgct agtgtctttc ctaaactggc
    45661 taggactttt aagactgtat ccaactgagg actagtcttt cctgtctcca tcctagctat
    45721 gacaggctgg cttattccac tgacttcttc cagctttttc tgactgattc cttgttcata
    45781 cctagcctca atcaactcgc tcatgatagc cactcgcata tcactttcaa ggatttcctc
    45841 cttgctaaag agctcagatg gacatccttc caattactcc caatagcact attcttcatc
    45901 acttaaccct ctttttttta cgtctatgta tttttaaaaa aatgagcgaa ttatgattcg
    45961 atagattgac cagtgggttt aaagttggtg ctagcctatt tcttaagcga ttttcctttt
    46021 ctaggataaa gtagatcctg cttgcttaac cccaattttc cacgatgaat ccaatagtaa
    46081 atggttgaaa ttcccacgtt aaccccttta gccatcacca tcatttcagg cgaaaatttt
    46141 tggttatgta tagtggagaa tcttttcctt tagtttctta agactgttga gcgtagtcgg
    46201 cagaataaat ctctttgaag cgcccttttc caagacattg tcggactgtc ccacgcttga
    46261 tttcagtgtg gatagtttga ggagcttttc caagtagaga ggcaatttct ctatttgatt
    46321 ttccttcttt tttccatcgt tcgattaagc gacggctatc gattgtcaaa tgtttgcctt
    46381 ttgtagtata attgtcttgc atttctgtgc cttttaatca tttcaatctt aaattggact
    46441 ttttttactt gggttgtact taatctatga ggaagacaag aaaaagaata tcaatcaagt
    46501 aaagtcacaa agttacatta gctccgagca accattgcaa attgaggtac tcacacaatg
    46561 attaaaacat ttctctctgc cctttcggtc attctctttt ctatccctat cataacttat
    46621 tcttttttcc catcttctaa tcttaacatt tggctatcta cccaacctat cttggcacag
    46681 atttatgcct tccccttagc tactgcaact atggctgcta ttttaagttt cttatttttt
    46741 ttcctatctt tttacaagaa aaataaacaa atacggtttt actctggcat tttgctctta
    46801 ctatcgctca tattactatt attcggaaca gataaaaccc tttcttctgc atcaaataag
    46861 actaaaacct taaaattagt aacttggaac gtcgctaatc aaatagaagc acaacatatt
    46921 gagcgaattt ttagccattt tgacgccgat atggctatat tccctgaact agctaccaat
    46981 atcagaggtg agcaagaaaa ccagagaatc aaactattgt ttcatcaagt tggactttct
    47041 atggccaact atgatatttt cacttctcca cctaccaata gtggaatagc tcctgtgact
    47101 gtgattgtca agaaaagtta tggtttctat acagaagcta aaacttttca tacaacacgg
    47161 ttcgggacaa ttgtattaca ttcgagaaaa caaaatatac cagatatcat tgccttgcat
    47221 actgctcctc ctctgccagg tttaatggaa atctggaagc aagacttaaa catcattcat
    47281 aatcaattgg cttcaaaata tccaaaggct attattgcag gtgattttaa tgcaactatg
    47341 cgtcatggag cacttgcaaa aataagctct catagggacg cattgaatgc acttccacct
    47401 tttgaaagag gaacttggaa tagccaaagt ccaaaacttt ttaatgcaac gatagatcat
    47461 atcttattgc ctaaaaacca ctactatgtt agagatttag acattgtaag ttttcaaaac
    47521 tctgatcata gatgtatttt tacagaaatc acattttaat tattttatat aaaattcccc
    47581 ctctagtgtt cataaactag agggggaatt tgtatcctac tatcgtttaa cgcacttctg
    47641 cattcacttt ttcttcgagc gatgcttgga ttttttccat atagcgtgcg acttcttcgt
    47701 ccgttaagct atcttctgga ttttggaagg tcaagctata agccatggac ttcataccaa
    47761 gtcccaattt ctcacctgag aagacgtcaa agagtttgat atctgtcaaa cgtttcacgc
    47821 cggcagcttg gatagcatct acaacttctt gatgagtcac ttctgccttg aggagaaggg
    47881 caacgtcacg gctgactgct gggaatttcg tgatttccac aaatggaaca gcaggttgga
    47941 gcgccccttc gatggctgaa aggttaagct cagctacata cgtttctgga atatcgtaag
    48001 ccttggcagt gactggatgc acttggccaa ggaaaccaag aacttggtca ccgagtgaaa
    48061 tcacggctgt acgacctgga tgaaggctag cgatttcaga tgttgctgta taggttactt
    48121 ggagtcccaa acgagtaaat agggcttcaa ggattccctt agcatagaag aaatcaactg
    48181 gaactgctgc tgtttggaaa tctttttcag caaccaagcc tgtcaaggca aaggcaaagc
    48241 tgttgatctc atttggaagt tcttcttttg gattacctgt ttgttcaaag acttttccaa
    48301 tctcataaag ggccaagttt ttattcttac gagccacgtt gtaggcaacg gtatcaagga
    48361 tccctgaaat catattttga cggaggactg aacgatccac agtcattggc cacatgagtt
    48421 cagtaaggtt acttggttga gctgtgaact caactgcttt ttcaggagtt gtcagagcat
    48481 aggtgataat ttctgtcaaa cctgctcctt cagcaatggt acgaacttga cggcggagtt
    48541 tttgtgtcac agtcaattca ccagctgtac catcgtcttt tggaaggctg gttggcaagc
    48601 ggtcatatcc atagatacga gcgatttctt caaagagatc agcttcgatt gtgatatccc
    48661 aacgacgacg tggtacgctg actgtaaagc tgtctgcatt tccagaaaga ccaaagccaa
    48721 gacgacggaa gacgtcttcg acatcagcat aagacagctc agttccgagg acacggttaa
    48781 catcagcaag agttgaagaa acttctacat ctgaagtatc aagctcaccc gctgaaacga
    48841 tacccttacg caccgtcgca cctgcaagtt ccgcaatcag gctagctgcc gcatcaaggg
    48901 cttcattaac tgttgccaca ttaattcctt tttcaaagcg agaagatgac tcagaacgaa
    48961 ggttcaggtg accacttgtc ttacggatag atttgccatt gaaaacagca gcttcaagga
    49021 caacacgact agatttttca gagatttctg ttgcttgacc acccatgaca cctgcaaggg
    49081 ctactggctt gtctgcaaca gtgatgacta ggtcattcac gtccaagtca cgttcttcac
    49141 cgtccaaggt caccaatttt tcaccagcac gcgcttcacg cacacggatg tcagtccctt
    49201 caaatgtgtc caagtcaaaa gcatgcatag gttgaccaaa gtagagcagg atgtagtttg
    49261 tcacgtctac aacgttattg atgggacgga tgccttcgtt catgagaagg ttttgcaacc
    49321 attgtggact tggtgcgata gtcacattgt ccaagatacg agctgcatag taaggcgcct
    49381 tgtctgtccc aatgctgaca gaaagggcat ctgccgcagc ttcattagtt tctgttagag
    49441 taaattcttt aaagttgact gccttgtcat agatggctgc cacttcgtga gccactccac
    49501 acatagaaag ggcatctgca cggtttggtg tgatggaaag ttcgatgatt tcatcatcca
    49561 agtctaggta agaaaagact tcctcacctg gcacggcatt ttctggcaag atttggatgc
    49621 catctgcgaa ttccttaggc acaactgagt cagaaattcc caattcacca agtgaacaga
    49681 tcattccaag tgactccaaa ccacggattt ttcctttttt gattttgtag ttatcagcga
    49741 tacgagctcc tggaagagcc accatgacct tgatcccagc acgcacattt ggggcaccac
    49801 aaacgatctg acgctcttct tcttcgccaa cgttaacctg acaaacatgg aggtgagtct
    49861 ctggcacatc ttcgcaagac aagacctcac cgacgacaat ttttgagaga ccagcagctg
    49921 gtgattcgac accctctacc tcgattcctg tagttgacat tttttcagcc aactcttgtg
    49981 atggcacatc aatgtccacc aattctttta accatttata agatacaagc ataatttagt
    50041 tctccagaat gaccattgcc acactggttc ttttcctttc ctatcatttc aatagaagaa
    50101 tcctcttctt accttaattt ctttctcagt aaccaatccg tatctacttt ttgaccaacc
    50161 ataaaatgat gttggctaaa tttttcaaaa ccatatcggt tataaaaggc ttgagctttt
    50221 gtattatgct cccaaacacc tagccaagcc caagaaaaac tattttttgt agcaagttca
    50281 agtgcgaatt caaacagttg cttacctagt ccaaatcctt ggaatttttg tagcacatag
    50341 aggcgttgaa tttcaaaagc gtcctctaat tctctctcag tttgagcact tccccagttg
    50401 actttgagaa aaccagctat ctcctcctca tgcataatga aataggtttc agagtcagga
    50461 tttcccaact cagttgacac agttttcaga ctataagcct cttcaaagta ttcctgtaac
    50521 tgctcttccg tattatcata cgcaaaggtt tcacgaaagg tttgtttggc aattttagcc
    50581 aacacctcaa catctgccat ttctactttt ctaatcatta tttaaactgt tctgagaagc
    50641 ggacatctcc ttggtagaat ccacggatat cgttgattcc ataacggagc atagctacac
    50701 gctcttgtcc aagaccaaag gcaaagccag agtatacagt cgcatcgata ccactcattt
    50761 caaggacacg tgggtgaacc ataccggccc ccataatttc gatccaacct gttttcttac
    50821 atacattaca gccttctcca ccacacttga agcaagaaac atccacctca acagatggct
    50881 ctgtgaatgg gaagtaagat ggacgcaaac gaatttgacg ctcttcacca aacatttttt
    50941 ggacaatcaa ctgaagcgtt ccttgaagat cagccataga gatatttttc ccaactacca
    51001 agccttcgat ttggtggaat tggtgactgt gggtcgcatc gtccgtatcg cgacggaaga
    51061 cacgccctgg cgagatcatc ttcaaaggac ctttagaaaa atcatgggca tccatagcac
    51121 gcgcctgaac tggagacgtg tgggtacgga gcaagatttc ttcagtgata tagaaagtat
    51181 cctgcatatc acgagctggg tggtcttttg gaaggttcat acgttcaaag ttatagtagt
    51241 cttgctccac ttcaaaacca tccacgactt gataacccat accgatgaag atatcttcga
    51301 tttcttcact ggtttgtgtc aaaacgtgac ggtgaccagt cgcaactgga cgacctggaa
    51361 gcgtcacatc gatactctcg ctagccagtt gagccgcgac tttcttttct tccaagagct
    51421 tagctgtttc ttcaaaagca gcagtcaaga catcacgagc ttcattgacg tgtttcccga
    51481 tgattggacg catctcagca gaaacatctt tcatcccttt gaggatttca gtgagcgaac
    51541 cctttttacc aaggacagag acacgcaaat cttgcatctc tttttcattt ccagcagtaa
    51601 tctgcttcaa gctagccagc gtttcttcgc gaagcgcttt taattgttct tcaatagttg
    51661 acatatttcc tccatcagtc tctcgtagat aaaaagaaaa ccacatgcca aaaactccac
    51721 tcggagcgtt gacacgcggt accatccgtt ttcatctgac aagtcagacc ttcatttcta
    51781 aatccatgcg caagtgaatt cacccagctt tcatatagag agcttgcagt cacggctctc
    51841 ctccctgata tacttccctt gggctactag tctttcagat tcctattcaa ttactactta
    51901 gtttatcaga tttttaccat tcttgcaaga cctatcttac ttctgcttgt tagcttattc
    51961 ttatctaact ttatagc
//
LOCUS       DBEJAU010000006        48644 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC323 isolate 683620
            SAMN38261939-rid24807223.denovo.006, whole genome shotgun sequence.
ACCESSION   DBEJAU010000006 DBEJAU010000000
VERSION     DBEJAU010000006.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261939
            Sequence Read Archive: SRR26833919
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 48644)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 48644)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576303.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576303.1
            Genome Coverage       :: 154x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/19/2025 01:05:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,121
            CDSs (total)                      :: 2,078
            Genes (coding)                    :: 1,943
            CDSs (with protein)               :: 1,943
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 36
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 72 of 135
            Pseudo Genes (incomplete)         :: 63 of 135
            Pseudo Genes (internal stop)      :: 51 of 135
            Pseudo Genes (multiple problems)  :: 46 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..48644
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261939-rid24807223.denovo.006"
                     /strain="GPSC323"
                     /isolate="683620"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            complement(227..1213)
                     /locus_tag="ACL29Z_000432"
     CDS             complement(227..1213)
                     /locus_tag="ACL29Z_000432"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001145427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HGR0068793.1"
                     /translation="MPVTIKDVAKAAGVSPSTVTRVIQNKSTISDETKKRVRKAMKEL
                     NYHPNLNARSLVSSYTQVIGLVLPDDSDAFYQNPFFPSVLRGISQVASENHYAIQIAT
                     GKDEKERLNAISQMVYGKRVDGLIFLYAQEEDPLVKLVAEEQFPFLILGKSLSPFIPL
                     VDNDNVQAGFDATEYFIKKGCKRIAFIGGSKKLFVTKDRLTGYEQALKHYKLTTDNNR
                     IYFADEFLEEKGYKFSKRLFKHDPQIDAIITTDSLLAEGVCNYIAKHQLDVPVLSFDS
                     VNPKLNLAAYVDINSLELGRVSLETILQIINDNKNNKQICYRQLIAHKIIEK"
     gene            complement(1223..2023)
                     /locus_tag="ACL29Z_000433"
     CDS             complement(1223..2023)
                     /locus_tag="ACL29Z_000433"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000938258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1189 domain-containing protein"
                     /protein_id="HGR0068794.1"
                     /translation="MLPYPFSFFSSILGFRKPLSKRFGLNWFQLLFTSIFLISLSMVP
                     IAIQNSSQETYPLETFIDNVYEPLTNEVVQDLSEHATIVDGTLTYTGTVSQASSVVIG
                     PSQIKELPKNLQLHFDTNELVISKESKELTRISYRAIQTESFKSKDSLTQAISKDWYQ
                     QNRVYISLFLVLGASFLFGLNFFIVSLGASLLLYITKKSRLFSFRTFKECYHFILNCL
                     GLPTLITLILGLFGQNMTTLITVQNILFVLYLVTIFYKTHFRDPNYHK"
     gene            complement(2276..3118)
                     /locus_tag="ACL29Z_000434"
     CDS             complement(2276..3118)
                     /locus_tag="ACL29Z_000434"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001065636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HGR0068795.1"
                     /translation="MNNSIKLKRRLTQSLTYLYLIGLSIVIIYPLLITIMSAFKAGNV
                     SAFKLDTNIDLNFDNFKGLFTETLYGTWYLNTLIIALITMAVQTSIIVLAGYAYSRYN
                     FLARKQSLVFFLIIQMVPTMAALTAFFVMALMLNALNHNWFLIFLYVGGGIPMNAWLM
                     KGYFDTVPMSLDESAKLDGAGHFRRFWQIVLPLVRPMVAVQALWAFMGPFGDYILSSF
                     LLREKEYFTVAVGLQTFVNNAKNLKIAYFSAGAILIALPICILFFFLQKNFVSGLTSG
                     GDKG"
     gene            complement(3120..4412)
                     /locus_tag="ACL29Z_000435"
     CDS             complement(3120..4412)
                     /locus_tag="ACL29Z_000435"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000414940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease subunit"
                     /protein_id="HGR0068796.1"
                     /translation="MEKQQPSKAALLSIIPGLGQIYNKQKAKGFIFLGVTIVFVLYFL
                     ALATPELSNLITLGDKPGRDNSLFMLIRGAFHLIFVIVYVLFYFSNIKDAHTIAKRIN
                     NGIPVPRTLKDMIKGIYENGFPYLLIIPSYVAMTFAIIFPVIVTLMIAFTNYDFQHLP
                     PNKLLDWVGLTNFTNIWSLSTFRSAFGSVLSWTIIWALAASTLQIVIGIFTAIIANQP
                     FIKGKRIFGVIFLLPWAVPAFITILTFSNMFNDSVGAINTQVLPILAKFLPFLDGALI
                     PWKTDPTWTKIALIMMQGWLGFPYIYVLTLGILQSIPNDLYEAAYIDGANAWQKFRNI
                     TFPMILAVAAPTLISQYTFNFNNFSIMYLFNGGGPGSVGGGAGSTDILISWIYRLTTG
                     TSPQYSMAAAVTLIISIIVISISMIAFKKLHAFDMEDV"
     gene            complement(4523..5794)
                     /locus_tag="ACL29Z_000436"
     CDS             complement(4523..5794)
                     /locus_tag="ACL29Z_000436"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000095461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HGR0068797.1"
                     /translation="MSSKFMKSTAVLGTVTLASLLLVACGSKTADKPADSGSSEVKEL
                     TVYVDEGYKSYIEEVAKAYEKEAGVKITLKTGDALGGLDKLSLDNQSGNVPDVMMAPY
                     DRVGSLGSDGQLSEVKLSDGAKTDDTTKSLVTAANGKVYGAPAVIESLVMYYNKDLVK
                     DAPKTFADLENLAKDSKYAFAGEDGKTTAFLADWTNFYYTYGLLAGNGAYVFGQNGKD
                     AKDIGLANDGSIAGINYAKSWYEKWPKGMQDTEGAGNLIQTQFQEGKTAAIIDGPWKA
                     QAFKDAKVNYGVATIPTLPNGKEYAAFGGGKAWVIPQAVKNLEASQKFVDFLVATEQQ
                     KVLYDKTNEIPANTEARSYAEGKNDELTTAVIKQFKNTQPLPNISQMSAVWDPAKNML
                     FDAVSGQKDAKTAANDAVTLIKETIKQKFGE"
     gene            6329..7861
                     /gene="malQ"
                     /locus_tag="ACL29Z_000437"
                     /pseudo
     CDS             6329..7861
                     /gene="malQ"
                     /locus_tag="ACL29Z_000437"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001847831.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0004134 - 4-alpha-glucanotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0005980 - glycogen catabolic process
                     [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="4-alpha-glucanotransferase"
     gene            7887..10145
                     /gene="glgP"
                     /locus_tag="ACL29Z_000438"
     CDS             7887..10145
                     /gene="glgP"
                     /locus_tag="ACL29Z_000438"
                     /EC_number="2.4.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000950172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004645 - 1,4-alpha-oligoglucan
                     phosphorylase activity [Evidence IEA];
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycogen/starch/alpha-glucan family
                     phosphorylase"
                     /protein_id="HGR0068798.1"
                     /translation="MLSLQEFVQNRYNKTIAECSNEELYLALLNYSKLASSQKPVNTG
                     KKKVYYISAEFLIGKLLSNNLINLGLYDDVKKELAAAGKDLIEVEEVELEPSLGNGGL
                     GRLAACFIDSIATLGLNGDGVGLNYHFGLFQQVLKNNQQETIPNAWLTEQNWLVCSSR
                     SYQVPFADFTLTSTLYDIDVTGYETATKNRLRLFDLDSVDSSIIKDGINFDKTDIARN
                     LTLFLYPDDSDRQGELLRIFQQYFMVSNGAQLIIDEAIEKGSNLHDLADYAVVQINDT
                     HPSMVIPELIRLLTARGIELDEAISIVRSMTAYTNHTILAEALEKWPLEFLQEVVPHL
                     VPIIEELDRRVKAEYKDPAVQIIDESGRVHMAHMDIHYGYSVNGVAALHTEILKNSEL
                     KAFYDLYPEKFNNKTNGITFRRWLMHANPRLSHYLDEILGDGWHHEADELEKLLSYED
                     KAAVKEKLESIKAHNKRKLARHLKEHQGVEINSNSIFDIQIKRLHEYKRQQMNALYVI
                     HKYLDIKAGNIPARPITIFFGGKAAPAYTIAQDIIHLILCMSEVIANDPAVAPHLQVV
                     MVENYNVTAASFLIPACDISEQISLASKEASGTGNMKFMLNGALTLGTMDGANVEIAE
                     LVGEENIYIFGEDSETVIDLYAKAAYKSSEFYAREAIKPLVDFIVSDAVLAAGNKERL
                     ERLYNELINKDWFMTLLDLEDYIKVKEQMLADYEDRDAWLDKVIVNISKAGFFSSDRT
                     IAQYNEDIWHLN"
     gene            complement(11190..11762)
                     /locus_tag="ACL29Z_000439"
     CDS             complement(11190..11762)
                     /locus_tag="ACL29Z_000439"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0068799.1"
                     /translation="MNKLMKFISFFLTSIVLIVSAIPSVSAVYASEQVSQIETNMELQ
                     PVTSLTEEQINTLANEIQSFHPDVSQQWIKEVINRQLQGDYTIPPTYSPFRAAWQGIT
                     VNQMGALLDTTIALALGGTTAGLANLIKVKGKHAAKSAIRSAISRYLGSWFVNDVALE
                     SAMNLLSPGTYLAQLWDKNDAIPNNGRINF"
     gene            11840..12046
                     /locus_tag="ACL29Z_000440"
     CDS             11840..12046
                     /locus_tag="ACL29Z_000440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000915303.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0068800.1"
                     /translation="MLKKYFSKYKWTDLFWILFVILTCLYIGNHDLFTLNHQEFSFRG
                     SVWGLVLALYHLLFIDKFVISNRK"
     gene            complement(12385..13233)
                     /locus_tag="ACL29Z_000441"
     CDS             complement(12385..13233)
                     /locus_tag="ACL29Z_000441"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001095523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative RNA methyltransferase"
                     /protein_id="HGR0068801.1"
                     /translation="MNTNLKPKLQRFASATAFACPICQENLTLLETNFKCCNRHSFDL
                     AKFGYVNLAPQIKQSANYDKENFQNRQQILEAGFYQAILDAVSDLLASSKTTTTILDI
                     GCGEGFYSRKLQESHSEKTFYAFDISKDSVQIAAKSEPNWAVNWFVGDLACLPIKDAN
                     MDILLDIFSPANYGEFRRVLSKDGILIKVIPTENHLKEIRQRVQDQLTNKEYSNQDIK
                     EHFQEHFTILSSQTASLTKTITAEQLQALLSMTPLLFHVDQSKIDWSQLTEITIEAEI
                     LVGKAF"
     gene            13385..13663
                     /locus_tag="ACL29Z_000442"
     CDS             13385..13663
                     /locus_tag="ACL29Z_000442"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003075836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF6110 family protein"
                     /protein_id="HGR0068802.1"
                     /translation="MLKEVLTVAKVAKKSSLFLGGVAFGTLGLKILASKEAKKGYSKA
                     LAKAYKLKDELDASVSVVKQHGDDVLQDAKYLYEQEKKEEQLDSLIGE"
     gene            13665..15728
                     /locus_tag="ACL29Z_000443"
     CDS             13665..15728
                     /locus_tag="ACL29Z_000443"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000008803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heavy metal translocating P-type ATPase"
                     /protein_id="HGR0068803.1"
                     /translation="MSFKVLHRGYQHIRLSSSFSLTLDIQDYLRSLARDEKGIESIQF
                     YMDQQHFTLRIKEGFSVLDNAEAFLKRIDKGKVSELMTLPIRREESAYSIVSGAAVKR
                     VLFRSFVPYPIRYIWTCYQALGYIREAYQTLARKELTMEVLDCSAILLSLFMNQSKTA
                     SNIMFMLDLGNHLDQWSLKKTATDLEQSLLAKESDVFLVQGDTVVSIKSSDVQIGDVL
                     ILSQGNEILFDGQVVSGLGMVNESSLTGESFPVEKRESDLVCANTVLETGELRIRVTD
                     NQMNSRILQLIKLMKKSEENKKTKQRYFIKMADKVVKYNFLGAGLTYLLTGSFSKAIS
                     FLLVDFSCALKISTPVAYLTVIKEGLNREMVIKDGDVLEKYLEVDTFLFDKTGTITTS
                     YPIVEKVLPFGDYSEEDILRISACLEEHIYHPIANAIVKQAEIEGIEHEEMHGKLQYI
                     ASKGIKSHIDGQPVLIGNYVLMQDEQIHISSEQNALIEEYKSHYNLLFLAYQNELIGM
                     FCIHTPLRKEAKTALDKLKAQGKKLILATGDTLIRTEELVKDLPFDQVYTDLKPDGKF
                     ELVEKLQKAGHTILMVGDGLNDSAALTLSDIGVVMNESADISKQMSDILLLDNRLDFF
                     QELDSLSSSLQTLIKKNIQDTVVVNSSLIGFGLFNWLSPSNLSILHNLTTLRIVLRSL
                     SIKNR"
     gene            complement(15806..17062)
                     /gene="tyrS"
                     /locus_tag="ACL29Z_000444"
     CDS             complement(15806..17062)
                     /gene="tyrS"
                     /locus_tag="ACL29Z_000444"
                     /EC_number="6.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000546895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004831 - tyrosine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006437 - tyrosyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine--tRNA ligase"
                     /protein_id="HGR0068804.1"
                     /translation="MHIFDELKERGLIFQTTDEEALRKALEEGQVSYYTGYDPTADSL
                     HLGHLVAILTSRRLQLAGHKPYALVGGATGLIGDPSFKDAERSLQTKDTVDGWVKSIQ
                     GQLSRFLDFENGENKAVMVNNYDWFGSISFIDFLRDIGKYFTVNYMMSKESVKKRIET
                     GISYTEFAYQIMQGYDFFVLNQDHNVTLQIGGSDQWGNMTAGTELLRRKADKTGHVIT
                     VPLITDATGKKFGKSEGNAVWLNPEKTSPYEMYQFWMNVMDADAVRFLKIFTFLSLDE
                     IEDIRKQFEAAPHERLAQKVLAREVVTLVHGEESYKEALNITEQLFAGNIKNLSVKEL
                     KQGLRGVPNYQVQADEHNNIVELLVSSGIVNSKRQAREDVQNGAIYVNGDRIQDLDYV
                     LSDADKLENELTVIRRGKKKYFVLTY"
     gene            17204..19669
                     /gene="pbp1b"
                     /locus_tag="ACL29Z_000445"
     CDS             17204..19669
                     /gene="pbp1b"
                     /locus_tag="ACL29Z_000445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein PBP1B"
                     /protein_id="HGR0068805.1"
                     /translation="MQNQLNELKRKMLEFFQQKQKNKKSARPGKKGSSTKKSKTLDKS
                     AIFPAILLSIKALFNLLFVLGFLGGMLGVGIALGYGVALFDKVRVPQTEELVNQVKDI
                     SSISEITYSDGTVIASIESDLLRTSISSEQISENLKKAIIATEDEHFKEHKGVVPKAV
                     IRATLGKFVGLGSSSGGSTLTQQLIKQQVVGDAPTLARKAAEIVDALALERAMNKDEI
                     LTTYLNVAPFGRNNKGQNIAGARQAAEGIFGVDASQLTVPQAAFLAGLPQSPITYSPY
                     ENTGELKSDEDLEIGLRRAKAVLYSMYRTGALSKDEYSQYKDYDLKQDFLPSGTVTGI
                     SRDYLYFTTLAEAQERMYDYLAQRDNVSAKELKNEATQKFYRDLAAKEIENGGYKITT
                     TIDQKIHSAMQSAVADYGYLLDDGTGRVEVGNVLMDNQTGAILGFVGGRNYQENQNNH
                     AFDTKRSPASTTKPLLAYGIAIDQGLMGSETILSNYPTNFANGNPIMYANSKGTGMMT
                     LGEALNYSWNIPAYWTYRMLREKGVDVKGYMEKMGYEIPEYGIESLPMGGGIEVTVAQ
                     HTNGYQTLANNGVYHQKHVISKIEAADGRVVYEYQDKPVQVYSKATATIMQGLLREVL
                     SSRVTTTFKSNLTSLNPTLANADWIGKTGTTNQDENMWLMLSTPRLTLGGWIGHDDNH
                     SLSRRAGYSNNSNYMAHLVNAIQQASPSIWGNERFALDPSVVKSEVLKSTGQKPGKVS
                     VEGKEVEVTGSTVTSYWANKSGAPATSYRFAIGGSDADYQNAWSSIVGSLPTPSSSSS
                     SSSSSSDSSNSSTTRPSSSRARR"
     gene            19734..20645
                     /locus_tag="ACL29Z_000446"
     CDS             19734..20645
                     /locus_tag="ACL29Z_000446"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007285066.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DMT family transporter"
                     /protein_id="HGR0068806.1"
                     /translation="MNQYQKKIVNGKIYSLLSGLIWGICGILGEYFFTHYQVSSGWIT
                     SMRLTLAGSLVLIWSAIQLKSQVLDIWRDKKNYLPFLAYAILGIFSVQYFFYLCVEYS
                     NATTATILQFISPVFILFYNRLVYQKRASKSAVFYVLVAMLGVCLMATKGDLSQLSMT
                     PLALITGLLSAMGVMFNVILPQPFAKRYGFVPTVGWGMILAGLFSNVLSPVYQLSFTL
                     DIWSILICLIIAFFGTAFAFFISMKAVSLVSPLVVSVISASEPLSSALLSVLFLGLVV
                     DWSFLLAIALIILPMIFLSIEEAKESR"
     gene            20875..21573
                     /gene="dapD"
                     /locus_tag="ACL29Z_000447"
     CDS             20875..21573
                     /gene="dapD"
                     /locus_tag="ACL29Z_000447"
                     /EC_number="2.3.1.89"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0047200 - tetrahydrodipicolinate
                     N-acetyltransferase activity [Evidence IEA];
                     GO_process: GO:0009089 - lysine biosynthetic process via
                     diaminopimelate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="2,3,4,5-tetrahydropyridine-2,6-dicarboxylate
                     N-acetyltransferase"
                     /protein_id="HGR0068807.1"
                     /translation="MTATKMNAQEIIQFIANAEKKTSVKVTFEGQLATAVPSSVVKLG
                     NVLFGDWKDVAPLLEGLVENQDYVVEQDARNSAVPLLDKRAINARIEPGAIIRDQVEI
                     GDNVVIMMGAVINIGAEIGAGTMIDMGAILGGRAIVGKNSHVGAGAVLAGVIEPASAE
                     PVRVGDNVLIGANAVVIEGVQIGSGSVVAAGAIVTQDVPENVVVAGVPARIIKEIDAQ
                     TQQKTALEDALRTL"
     gene            21641..22771
                     /locus_tag="ACL29Z_000448"
     CDS             21641..22771
                     /locus_tag="ACL29Z_000448"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006151341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetyldiaminopimelate deacetylase"
                     /protein_id="HGR0068808.1"
                     /translation="MLDLIQTRRDLHQIPEIGLEEFKTQAYLLDVIEKLTTGKDFVQI
                     RTWRTGILVYLQGSQPERTIGWRTDIDGLPIVEQTGLPFASQHQGRMHACGHDFHMTI
                     ALGCLERALEEQPKNNLLFLFQPAEENEAGGMLMYEAGAFGDWLPDQFYGLHVRPDLK
                     VGQIATNTHTLFAGTCEVKIRFKGKGGHAAFPHEANDALVAASYFVTQVQSVVSRNVN
                     PIEGAVVTFGVFQAGTTNNVITDTAFLHGTIRALTQDMSLLVQKRVKTVAEGVAAAFD
                     MEVEVELKQGGYLPVENNPALARELMDFFDEKDGIELIDIEPAMTGEDFGYLLSKVDG
                     VMFWLGIDSPYALHHPQMSPKEEVLAIGVAAVSSFLKKKAAE"
     gene            22783..23322
                     /locus_tag="ACL29Z_000449"
     CDS             22783..23322
                     /locus_tag="ACL29Z_000449"
                     /EC_number="6.3.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030272 - 5-formyltetrahydrofolate
                     cyclo-ligase activity [Evidence IEA];
                     GO_process: GO:0006730 - one-carbon metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="5-formyltetrahydrofolate cyclo-ligase"
                     /protein_id="HGR0068809.1"
                     /translation="MKSELRKQVLQGMKAISQEQKQFIDQTLTERLLHHPFYQEAKVI
                     ATYLSFPHEFQTQELIEQALKDGKKVLIPKTYPKGRMDFVVYDPQQLVKTSFGLLEPQ
                     GDLEVVDASQIDLIHVPGLAFTTKGYRIGYGGGYYDRYLEHFSGHTLSTVHPCQIQDF
                     IPENHDIPVQEVLIDEGNL"
     gene            23306..23983
                     /locus_tag="ACL29Z_000450"
     CDS             23306..23983
                     /locus_tag="ACL29Z_000450"
                     /EC_number="3.4.21.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004252 - serine-type endopeptidase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="rhomboid family intramembrane serine protease"
                     /protein_id="HGR0068810.1"
                     /translation="MKEIFDRRYPVTSFFLLVTALVFLLMLVTAGGNFDRADTLFRFG
                     AMYGPAIRLFPEQVWRLLSAIFVHIGWEHFIVNMLSLYYLGRQVEEIFGSKQFFFLYL
                     LSGMMGNLFVFVFSPKSLAAGASTSLYGLFAAIIILRYATRNPYIQQLGQSYLTLFVV
                     NIIGSVLIPGISLAGHIGGAVGGAFLAVIFPVRGEKRMYNTSQRLGAVVLFVGLAILL
                     FYKGMGM"
     gene            complement(24050..24949)
                     /gene="galU"
                     /locus_tag="ACL29Z_000451"
     CDS             complement(24050..24949)
                     /gene="galU"
                     /locus_tag="ACL29Z_000451"
                     /EC_number="2.7.7.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000202216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003983 - UTP:glucose-1-phosphate
                     uridylyltransferase activity [Evidence IEA];
                     GO_process: GO:0006011 - UDP-glucose metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UTP--glucose-1-phosphate uridylyltransferase
                     GalU"
                     /protein_id="HGR0068811.1"
                     /translation="MTSKVRKAVIPAAGLGTRFLPATKALAKEMLPIVDKPTIQFIVE
                     EALKSGIEDILVVTGKSKRSIEDHFDSNFELEYNLKEKGKTDLLKLVDETTGMRLHFI
                     RQTHPRGLGDAVLQAKAFVGNEPFVVMLGDDLMDITDEKAVPLTKQLMDDYERTHAST
                     IAVMPVPHDEVSAYGVIAPQGEGKDGLYSVETFVEKPAPEDAPSDLAIIGRYLLTPEI
                     FEILEKQAPGAGNEIQLTDAIDTLNKTQRVFAREFTGARYDVGDKFGFMKTSIDYALK
                     HPQVKDDLKNYLIQLGKELTEKE"
     gene            complement(24971..25987)
                     /locus_tag="ACL29Z_000452"
     CDS             complement(24971..25987)
                     /locus_tag="ACL29Z_000452"
                     /EC_number="1.1.1.94"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000415108.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009331 - glycerol-3-phosphate
                     dehydrogenase (FAD) complex [Evidence IEA];
                     GO_function: GO:0047952 - glycerol-3-phosphate
                     dehydrogenase [NAD(P)+] activity [Evidence IEA];
                     GO_function: GO:0051287 - NAD binding [Evidence IEA];
                     GO_process: GO:0046168 - glycerol-3-phosphate catabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent glycerol-3-phosphate
                     dehydrogenase"
                     /protein_id="HGR0068812.1"
                     /translation="MEKQTVAVLGPGSWGTALSQVLNDNGHEVRIWGNLPEQINEINT
                     HHTNKHYFKDVVLDENIIAYTDLAETLKNVDAILFVVPTKVTRLVAQQVAQTLDHKVI
                     IMHASKGLEPDSHKRLSTILEEEIPEHLRSDIVVVSGPSHAEETIVRDLTLITAASKD
                     LQTAQYVQELFSNHYFRLYTNTDVIGVETAGALKNIIAVGAGALHGLGFGDNAKAAII
                     ARGLAEITRLGVALGASPLTYSGLSGVGDLIVTGTSIHSRNWRAGDALGRGESLADIE
                     ANMGMVIEGISTTRAAYELAQELGVYMPITQAIYQVIYHGTNIKDAIYDIMNNEFKAE
                     NEWS"
     gene            26235..26339
                     /locus_tag="ACL29Z_000453"
                     /pseudo
     CDS             26235..26339
                     /locus_tag="ACL29Z_000453"
                     /inference="COORDINATES: protein motif:HMM:NF024252.4"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="XRE family transcriptional regulator"
     gene            26504..26638
                     /locus_tag="ACL29Z_000454"
     CDS             26504..26638
                     /locus_tag="ACL29Z_000454"
                     /inference="COORDINATES: protein motif:HMM:NF037495.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0068813.1"
                     /translation="MFEEYYDRLPEEERFIIPNYSYLALTNYTVQKLPEKLVEILSFW
                     "
     gene            complement(26843..27184)
                     /locus_tag="ACL29Z_000455"
                     /pseudo
     CDS             complement(26843..27184)
                     /locus_tag="ACL29Z_000455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001808790.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(27246..27896)
                     /gene="phoU"
                     /locus_tag="ACL29Z_000456"
     CDS             complement(27246..27896)
                     /gene="phoU"
                     /locus_tag="ACL29Z_000456"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001245788.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006817 - phosphate ion transport [Evidence
                     IEA];
                     GO_process: GO:0030643 - intracellular phosphate ion
                     homeostasis [Evidence IEA];
                     GO_process: GO:0045936 - negative regulation of phosphate
                     metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate signaling complex protein PhoU"
                     /protein_id="HGR0068814.1"
                     /translation="MRNQFDLELHELEQSFLGLGQLVLETASKALLALASKDKEMAEL
                     IINKDHAINQGQSAIELACARLLALQQPQVSDLRFVISIMSSCSDLERMGDHMAGIAK
                     AVLQLKENQLAPDEEQLHQMGKLSLSMLADLLVAFPLHQASKAISIAQKDEQIDQYYY
                     ALSKEIIGLMKDQETSIPNGTQYLYIIGHLERFADYIANICERLVYLETGELVDLN"
     gene            complement(27911..28663)
                     /gene="pstB"
                     /locus_tag="ACL29Z_000457"
     CDS             complement(27911..28663)
                     /gene="pstB"
                     /locus_tag="ACL29Z_000457"
                     /EC_number="7.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003101281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009898 - cytoplasmic side of plasma
                     membrane [Evidence IEA];
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0015415 - ATPase-coupled phosphate ion
                     transmembrane transporter activity [Evidence IEA];
                     GO_process: GO:0006817 - phosphate ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter ATP-binding protein
                     PstB"
                     /protein_id="HGR0068815.1"
                     /translation="MGTFSVRHLDLFYGDFQALKNISIQLPERQITALIGPSGCGKST
                     FLKTLNRMNDLVPSCHIEGQVLLDEQDIYSSKFNLNQLRKRVGMVFQQPNPFAMSIYD
                     NVAYGPRTHGIRDKKQLDALVEKSLKGAAIWEEVKDDLKKSAMSLSGGQQQRLCIARA
                     LAVEPDILLMDEPTSALDPISTLKIEDLIQQLKKDYTIIIVTHNMQQASRISDKTAFF
                     LTGEICEFGDTVDVFTNPKDQRTEDYISGRFG"
     gene            complement(28665..29480)
                     /gene="pstA"
                     /locus_tag="ACL29Z_000458"
     CDS             complement(28665..29480)
                     /gene="pstA"
                     /locus_tag="ACL29Z_000458"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015057412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0015415 - ATPase-coupled phosphate ion
                     transmembrane transporter activity [Evidence IEA];
                     GO_process: GO:0006817 - phosphate ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease PstA"
                     /protein_id="HGR0068816.1"
                     /translation="MSKYLLKLLVYCFSALTFGSLFLIIGFILIKGLPHLSLSLFSWT
                     YTSENISLMPAIISTVILVFGALLLALPIGIFAGFYLVEYTKKDSLCVKIMRLASDTL
                     SGIPSIVFGLFGMLFFVVFLGFQYSLLSGILTSVIMVLPVIIRSTEEALLSVSDSMRQ
                     ASYGLGAGKLRTVFRIVLPVAMPGILAGVILAIGRIVGETAALMYTLGTSTNTPSSLM
                     SSGRSLALHMYMLSSEGLHVNEAYATGVILIITVLMINTLSSLLSRKLVKGAS"
     gene            complement(29473..30336)
                     /gene="pstC"
                     /locus_tag="ACL29Z_000459"
     CDS             complement(29473..30336)
                     /gene="pstC"
                     /locus_tag="ACL29Z_000459"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000595184.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0015415 - ATPase-coupled phosphate ion
                     transmembrane transporter activity [Evidence IEA];
                     GO_process: GO:0006817 - phosphate ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease subunit PstC"
                     /protein_id="HGR0068817.1"
                     /translation="MIKQAFKEAVFRAIFFMSATVAVVAILLICFFIFSNGLPFMANY
                     GFARFLLGSDWSPTNIPASYGILPMIVGSLLITLGAIVIGVPTGILTSVFMVYYCPKP
                     VYGFLKSAINLMAAIPSIVYGFFGLQLLVPWIRSFLGNGMSVLTASLLLGIMILPTII
                     SLSESAIRTVPKTYYSGSLALGASHERSIFSVILPAARSGILSAVILGIGRAVGETMA
                     VILVAGNQPIIPSGLFSGTRTLTTNIVLEMAYASGQHREALIATSAVLFFLILLINAY
                     FAYLKGKSSYE"
     gene            complement(30454..31329)
                     /locus_tag="ACL29Z_000460"
     CDS             complement(30454..31329)
                     /locus_tag="ACL29Z_000460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000669496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="substrate-binding domain-containing protein"
                     /protein_id="HGR0068818.1"
                     /translation="MKFKKMLTLAAIGLSGFGLVACGNQSAASKQSASGTIEVISREN
                     GSGTRGAFTEITGILKKDGDKKIDNTAKTAVIQNSTEGVLSAVQGNANAIGYISLGSL
                     TKSVKALEIDGVKASRDTVLDGEYPLQRPFNIVWSSNLSKLGQDFISFIHSKQGQQVV
                     TDNKFIEAKTETTEYTSQHLSGKLSVVGSTSVSSLMEKLAEAYKKENPEVTIDITSNG
                     SSAGITAVKEKTADIGMVSRELTPEEGKSLTHDAIALDGIAVVVNNDNKASQVSMAEL
                     ADVFSGKLTTWDKIK"
     gene            complement(31496..32827)
                     /gene="pnpS"
                     /locus_tag="ACL29Z_000461"
     CDS             complement(31496..32827)
                     /gene="pnpS"
                     /locus_tag="ACL29Z_000461"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000833277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system histidine kinase PnpS"
                     /protein_id="HGR0068819.1"
                     /translation="MKRYLQFWLVNLSVSLILIAGMALTWISKGIGLFLLALSLGQGG
                     YWLFCLWKWEVAFETLHQPLLTSSEYFLEKGQEDLKSLAQYVSGLKTKVSQQDQQYKD
                     LAETMEVLLSHLTMGTFLVSAQGQMLLSSRSLPHYFPDVDGDISSLDDLKRMDIRNLV
                     HQAFDQKTRLKQEVSGFHEGDLILEVTAVPVFSPTQSVEAVLVLLYDLTTIRTYEKLN
                     LAFVSNASHELRTPVTSIKGFAETIKGMSAEEEALKDDFLDIIYKESLRLEHIVEHLL
                     TLSKAQQMPIQWTTLSLAEFVQDLTQSLQPQLKKKDLQLKVQVPDDVTLVSDSQLLSQ
                     ILLNLLSNAIRYTEQGGKIEVKTQKVNEGIKISVSDTGIGISQLEQERIFERFYRVNK
                     GRSRQTGGTGLGLAIVKELSQLLGGQVTVTSQLGRGSCFTIFLPNQSFAQD"
     gene            complement(32828..33535)
                     /locus_tag="ACL29Z_000462"
     CDS             complement(32828..33535)
                     /locus_tag="ACL29Z_000462"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000166478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HGR0068820.1"
                     /translation="MTKQVLLVDDEEHILKLLDYHLSKEGFSTQLVTNGRKALALAET
                     EPFDFILLDIMLPQLDGMEVCKRLRAKGVKTPIMMVSAKSDEFDKVLALELGADDYLT
                     KPFSPRELLARVKAVLRRTKGEQEGDDSDNIADDSWLFGTLKVYPERHEVYKANKLLS
                     LTPKEFELLLYLMKHPNMTLTRERLLERIWGYDFGQETRLVDVHIGKLREKIEDNPKA
                     PQFIRTIRGYGYKFKEL"
     gene            complement(33619..34104)
                     /locus_tag="ACL29Z_000463"
     CDS             complement(33619..34104)
                     /locus_tag="ACL29Z_000463"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001855144.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cupin domain-containing protein"
                     /protein_id="HGR0068821.1"
                     /translation="MAPTDKEDLIRTLELAPHIEGGYFRQTKKASDTINLAGKGRALY
                     TSIYFLLEETNPSHFHRLTADEIWYFHAGSPLTVHMITADGHYEAVTLGLDISKGQQL
                     HYCVPKGTIWGSTVDKDYALVSCLVAPGFEFEDFELFERADLLATYPEHKEMIEHLTR
                     Y"
     gene            34090..34647
                     /locus_tag="ACL29Z_000464"
                     /pseudo
     CDS             34090..34647
                     /locus_tag="ACL29Z_000464"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase family protein"
     gene            complement(34962..36653)
                     /gene="argS"
                     /locus_tag="ACL29Z_000465"
     CDS             complement(34962..36653)
                     /gene="argS"
                     /locus_tag="ACL29Z_000465"
                     /EC_number="6.1.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015632348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004814 - arginine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006420 - arginyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="arginine--tRNA ligase"
                     /protein_id="HGR0068822.1"
                     /translation="MNTKELIASELASIIDSLDQEAILKLLETPKNSEMGDIAFPAFS
                     LAKVERKAPQMIAAELAEKMNSQAFEKVVATGPYVNFFLDKSAISAQVLQAVTTEKEH
                     YADQNIGKQENVVIDMSSPNIAKPFSIGHLRSTVIGDSLSHIFQKIGYQTVKVNHLGD
                     WGKQFGMLIVAYKKWGDEEAVKAHPIDELLKLYVRINAEAENDPSLDEEAREWFRKLE
                     NGDEEALALWQWFRDESLVEFNRLYNELKVEFDSYNGEAFYNDKMDAVVDILSEKGLL
                     LESEGAQVVNLEKYGIEHPALIKKSDGATLYITRDLAAALYRKNEYQFAKSIYVVGQE
                     QSAHFKQLKAVLQEMGYDWSDDITHVPFGLVTKEGKKLSTRKGNVILLEPTVAEAVSR
                     AKVQIEAKNPELENKDQVAHAVGVGAIKFYDLKTDRTNGYDFDLEAMVSFEGETGPYV
                     QYAYARIQSILRKADFKPETAGNYSLNDTESWEIIKLIQDFPRIINRAADNFEPSIIA
                     KFAISLAQSFNKYYAHTRILDESPERDSRLALSYATAVVLKEALRLLGVEAPEKM"
     gene            36789..37235
                     /gene="argR"
                     /locus_tag="ACL29Z_000466"
     CDS             36789..37235
                     /gene="argR"
                     /locus_tag="ACL29Z_000466"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001227366.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA];
                     GO_process: GO:0006525 - arginine metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="arginine repressor"
                     /protein_id="HGR0068823.1"
                     /translation="MRKRDRHQLIKKMITEEKLSTQKEIQDRLEAHNVCVTQTTLSRD
                     LREIGLTKVKKNDMVYYVLVNETEKIDLVEFLSHHLEGVARAEFTLVLHTKLGEASVL
                     ANIVDVNKDKWILGTVAGANTLLVICRDQHVAKLMEDRLLDLMKDK"
     gene            37286..39820
                     /gene="mutS"
                     /locus_tag="ACL29Z_000467"
     CDS             37286..39820
                     /gene="mutS"
                     /locus_tag="ACL29Z_000467"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0030983 - mismatched DNA binding [Evidence
                     IEA];
                     GO_process: GO:0006298 - mismatch repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA mismatch repair protein MutS"
                     /protein_id="HGR0068824.1"
                     /translation="MAIEKLSPGMQQYVDIKKQYPDAFLLFRMGDFYELFYEDAVNAA
                     QILEISLTSRNKNADNPIPMAGVPYHSAQQYIDVLIEQGYKVAIAEQMEDPKQAVGVV
                     KREVVQVITPGTVVDSSKPDSQNNFLVSIDREGNQFGLAYMDLVTGDFYVTGLLDFTL
                     VCGEIRNLKAREVVLGYDLSEEEEQILSRQMNLVLSYEKESFEDLHLLDLRLATVEQT
                     ASSKLLQYVHRTQMRELNHLKPVIRYEIKDFLQMDYATKASLDLVENARSGKKQGSLF
                     WLLDETKTAMGMRLLRSWIHRPLIDKERIVQRQEVVQVFLDHFFERSDLTDSLKGVYD
                     IERLASRVSFGKTNPKDLLQLATTLSSVPRIRAILEGMEQPTLAYLIAQLDAIPELES
                     LISAAIAPEAPHVITDGGIIRTGFDETLDKYRCVLREGTSWIAEIEAKERENSGISTL
                     KIDYNKKDGYYFHVTNSQLGNVPAHFFRKATLKNSERFGTEELARIEGDMLEAREKSA
                     NLEYEIFMRIREEVGKYIQRLQALAQGIATVDVLQSLAVVAETQHLIRPEFGDDSQID
                     IRKGRHAVVEKVMGAQTYIPNTIQMAEDTSIQLVTGPNMSGKSTYMRQLAMTAVMAQL
                     GSYVPAESAHLPIFDAIFTRIGAADDLVSGQSTFMVEMMEANNAISHATKNSLILFDE
                     LGRGTATYDGMALAQSIIEYIHEHIGAKTLFATHYHELTSLESSLQHLVNVHVATLEQ
                     DGQVTFLHKIEPGPADKSYGIHVAKIAGLPADLLARADKILTQLENQGTESPPPMRQT
                     SAVTEQISLFDRAEEHPILAELAKLDVYNMTPMQVMNVLVELKQKL"
     gene            39967..41661
                     /gene="patA"
                     /locus_tag="ACL29Z_000468"
     CDS             39967..41661
                     /gene="patA"
                     /locus_tag="ACL29Z_000468"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000908145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux ABC transporter subunit PatA"
                     /protein_id="HGR0068825.1"
                     /translation="MLIQKIKTYKWQALASLLMTGLMVASSLLQPRYLQEVLDALLTG
                     KYEAIYSIGAWLIGVAVVGLVAGGLNVVLAAYIAQGVSSDLREDAFRKIQTFSYADIE
                     QFNAGNLVVRMTNDINQIQNVVMMTFQILFRLPLLFIGSFILAVQTLPSLWWVIVLMV
                     VLIFGLTAVMMGMMGPRFAKFQTLLERINAIAKENLRGVRVVKSFVQEKEQFAKFTEV
                     SDELFGQNLYIGYAFSVVEPFMMLVGYGAVFLSIWLVAGMVQSDPSVVGSIASFVNYL
                     SQIIFTIVMVGFLGNSVSRAMISMRRIREILDAEPAMTFKDIPDEELVGSLSFENVTF
                     TYPMDKEPMLKDVSFTIEPGQMVGVVGATGAGKSTLAQLIPRLFDPQNGAIKIGGKDI
                     REVSEGTLRKTVSIVLQRAILFSGTIADNLRQGKGNATLFEMERAANIAQASEFIHRM
                     EKTFESPVEERGTNFSGGQKQRMSIARGIVSNPRILIFDDSTSALDAKSERLVQEALN
                     KDLKGTTTIIIAQKISSVVHADKILVLNQGRLIGQGTHADLVANNAVYREIYETQK"
     gene            complement(41811..42260)
                     /locus_tag="ACL29Z_000469"
                     /pseudo
     CDS             complement(41811..42260)
                     /locus_tag="ACL29Z_000469"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844241.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            42452..44218
                     /gene="patB"
                     /locus_tag="ACL29Z_000470"
     CDS             42452..44218
                     /gene="patB"
                     /locus_tag="ACL29Z_000470"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000859866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux ABC transporter subunit PatB"
                     /protein_id="HGR0068826.1"
                     /translation="MKTVQFFWHYFKVYKFSFVVVILMIVLATFAQALFPVFSGQAVT
                     QLANLVQAYQNGNPELVWQSLSGIMVNLGLLVLVLFISSVIYMCLMTRVIAESTNEMR
                     KGLFGKLAQLTVSFFDRRQDGDILSHFTSDLDNILQAFNESLIQVMSNIVLYIGLILV
                     MFSRNVTLALITIASTPLAFLMLIFIVKMARKYTNLQQKEVGKLNAYMDESISGQKAV
                     IVQGIQEDMMAGFLEQNERVRKATFKGRMFSGILFPVMNGMSLINTAIVIFAGSAVLL
                     NDKSIETSTALGLIVMFAQFSQQYYQPIIQVAASWGSLQLAFTGAERIQEMFDAEEEI
                     RPEKAPTFTKLQESVEISHIDFSYLPDKPILKDVSISAPKGQMTAVVGPTGSGKTTIM
                     NLINRFYDVDAGGIYFDGKDIRGYDLDSLRSKVGIVLQDSVLFSGTIRDNIRFGVPDA
                     SQEMVEVAAKATHIHDYIESLPDKYDTLIDDDQSIFSTGQKQLISIARTLMTDPEVLI
                     LDEATSNVDTVTESKIQHAMEVVVAGRTSFVIAHRLKTILNADQIIVLKDGEVIERGN
                     HHELLKLGGFYSELYHNQFVFE"
     gene            44357..45046
                     /locus_tag="ACL29Z_000471"
     CDS             44357..45046
                     /locus_tag="ACL29Z_000471"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466883.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gamma-glutamyl-gamma-aminobutyrate hydrolase
                     family protein"
                     /protein_id="HGR0068827.1"
                     /translation="MARTVVGVAANLCPVDAEGKIIHSSVSCRFAEIIRQVGGLPLVI
                     PVGDESVVRDYVEMIDKLILTGGQNVHPQFYGEKKTVESDDYNLVRDEFELALLKEAL
                     RQNKPIMAICRGVQLVNVAFGGTLNQEIEGHWQGLPFGTSHSIETVEGSVVAKLFGKE
                     SQVNSVHRQSIKDLAPNFRVTAIDSRDQTIEAIESIDEHRIIGLQWHPEFLVNEEDGN
                     LELFEYLLNEL"
     gene            45050..45229
                     /locus_tag="ACL29Z_000472"
     CDS             45050..45229
                     /locus_tag="ACL29Z_000472"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866816.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0068828.1"
                     /translation="MEHLVVLSFIFSKFLECGILRKRLNSDKNWRNSTKKLEKNEGKR
                     YDRKEEILEEEHVTY"
     gene            45216..46565
                     /locus_tag="ACL29Z_000473"
     CDS             45216..46565
                     /locus_tag="ACL29Z_000473"
                     /EC_number="5.3.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017648691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004347 - glucose-6-phosphate isomerase
                     activity [Evidence IEA];
                     GO_process: GO:0006096 - glycolytic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-6-phosphate isomerase"
                     /protein_id="HGR0068829.1"
                     /translation="MSHIKFDYSKVLDKFVAPHEVEYMQSQVTAADELIRKGTGAGSD
                     FLGWLDLPEKYDREEFDRILKAAEQIKSDSDVLVVIGIGGSYLGAKAAIDFLNHHFAN
                     LQTKEERKAPQILYAGNSISSTYLADLVEYVADKDFSVNVISKSGTTTEPAIAFRVFK
                     ELLVKKYGQEEANKRIYATTDRQKGAVKVEADANGWGTFVVPDDIGGRFSVLTAVGLL
                     PIAASGADIKALMEGANAARKDYTSDKISENEAYQYAAVRNILYRKGYATEILVNYEP
                     SLQYFSEWWKQLAGESEGKDQKGIYPTSANFSTDLHSLGQFIQEGTRIMFETVVRVDK
                     PRKNVLIPTLEEDLDGLGYLQGKDVDFVNKKATDGVLLAHTDGDVPNMYVTLPEQDAF
                     TLGYTIYFFELAIALSGYLNAINPFDQPGVEAYKRNMFALLGKPGFEELSKELNARL"
     gene            46689..48149
                     /gene="gltX"
                     /locus_tag="ACL29Z_000474"
     CDS             46689..48149
                     /gene="gltX"
                     /locus_tag="ACL29Z_000474"
                     /EC_number="6.1.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004818 - glutamate-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006424 - glutamyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate--tRNA ligase"
                     /protein_id="HGR0068830.1"
                     /translation="MSKDIRVRYAPSPTGLLHIGNARTALFNYLYARHHGGTFLIRIE
                     DTDRKRHVEDGERSQLENLRWLGMDWDESPESHENYRQSERLDLYQKYIDQLLAEGKA
                     YKSYVTEEELAAERERQEVAGETPRYINEYLGMSEEEKAAYIAEREAAGIIPTVRLAV
                     NESGIYKWHDMVKGDIEFEGGNIGGDWIIQKKDGYPTYNFAVAIDDHDMQISHVIRGD
                     DHIANTPKQLMVYEALGWEAPEFGHMTLIINSETGKKLSKRDTNTLQFIEDYRKKGYL
                     PEAVFNFIALLGWNPGGEDEIFSREELIKLFDENRLSKSPAAFDQKKLDWMSNDYIKN
                     ADLETIFEMAKPFLEEAGRLTDKAEKLVELYKPQIKSVDEIIPLTDLFFSDFPELTEA
                     EREVMTGETVPTVLEAFKAKLEEMTDNEFVTENIFPQIKAVQKETGIKGKNLFMPIRI
                     AVSGEMHGPELPDTIFLLGREKSIQHIENMLKEISK"
     gene            48163..48597
                     /locus_tag="ACL29Z_000475"
     CDS             48163..48597
                     /locus_tag="ACL29Z_000475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytidine deaminase"
                     /protein_id="HGR0068831.1"
                     /translation="MDIWEKMYEEAQKLYNPHEVSDFVYANHVVAAVEAEDGQIFTGF
                     CMEGTCGVFHLCAERAALFNMYQFSGQTKVKKVLAFRDKPPYGGSSAMPCGACREFLL
                     ELNAENKDAEFMMDYNIRKTVKVAELIPYWWGEERASKFNER"
BASE COUNT        14351 a         9231 c        10553 g        14509 t
ORIGIN      
        1 tgacttcgtc agttctatcc acaacctcaa aacagtgttt tgagcaacct gcggctagct
       61 tcctagtttg cactttgatt ttcattgagt ataaaaagat cttgggaaaa gactcaattt
      121 cagtagaaaa ggaagtaaat cttcccacat taaaacgcat agtatcaagt tttttcaata
      181 cctgatagta tgcgtttttg cttttaacga ctttttgccc agtctcttat ttttcgataa
      241 ttttgtgggc gatcaattga cggtaacaaa tttgtttatt gtttttatta tcattaataa
      301 tctggagaat agtttcaagg gaaacacgac caagctctaa actattgata tcgacatagg
      361 ctgccaagtt gagcttggga ttaaccgagt caaagctgag aacagggaca tccagctggt
      421 gtttggcaat atagttacaa acaccttcag ctaggaggct atcggttgtg atgatagcat
      481 caatttgtgg atcgtgcttg aataatcgct tgctaaattt atagcccttt tcttccagaa
      541 actcgtcggc aaagtagatg cgattgttgt cagtggtaag tttgtaatgt ttaagcgcct
      601 gttcatagcc tgttaaacgg tctttggtca cgaagagctt tttacttcct ccgataaagg
      661 caatgcgttt gcagcctttt ttgatgaaat attcagtcgc atcaaaacca gcttgaacat
      721 tgtcgttgtc gacaagtggg atgaaaggag atagagattt acctaagata aggaagggga
      781 actgttcttc tgcgacgagt tttacgagag ggtcttcttc ttgggcatag agaaagatta
      841 gcccatctac acgcttgccg tagaccattt gtgaaatagc gttgagacgc tccttctcat
      901 ctttccctgt tgctatctga atggcatagt ggttttcaga tgcgacttga gagatgccac
      961 gtagaaccga tggaaagaaa ggattctggt agaaggcgtc tgagtcatca ggaagaacta
     1021 atccgataac ctgagtatag ctgcttacca agctacgagc gttgaggttt gggtggtagt
     1081 tgagttcctt catagctttg cgaacgcgtt tttttgtttc gtcgctaatg gttgatttat
     1141 tttgaataac acgggttacg gttgaaggcg aaacaccagc agccttggcc acgtctttaa
     1201 tcgtaacggg cataaaaatc tcctatttat ggtaatttgg atcacggaaa tgtgttttat
     1261 aaaagatagt gaccagatac agaacaaaaa gaatattttg tacagtaatc agggttgtca
     1321 tattttggcc aaataatccc aaaataagtg taatcagagt cggcaatcct aaacagttca
     1381 agataaagtg atagcactct ttaaaggttc taaatgaaaa gaggcgtgat ttcttagtga
     1441 tataaaggag aagactagct cctagagaga cgataaagaa attcaaacca aagaggaagc
     1501 tcgcaccgag aactaggaag aggctgatat agacacgatt ttgttggtac cagtctttag
     1561 aaattgcttg ggtcaagctg tctttgcttt tgaaactctc agtctgaatg gctcggtaag
     1621 agatgcgggt cagttccttg ctttccttgc tgatgactag ctcatttgta tcgaaatgca
     1681 gttgcaagtt cttaggtaat tccttgattt gacttggacc aatcacaaca gaagaggctt
     1741 gactaactgt tccagtataa gttaatgtgc catcgacaat tgtagcatgt tcagaaagat
     1801 cctggacaac ctcatttgtc agaggttcat agacattatc gataaaagtt tctagcggat
     1861 aggtctcctg ggagctgttt tggatagcaa tgggtaccat agacaagctg ataaggaaga
     1921 tactggtaaa gagaagttga aaccagttga gcccgaaacg tttggacagg ggcttacgaa
     1981 accccaaaat acttgaaaaa aaggaaaatg gatatggaag cataggtatc tttctaaaag
     2041 gtgttttcta tataagtatt attatataga gaaatgcgct ttatttcaag tctaggagaa
     2101 aaattgcttg ctacaaggat attatttaca gtgacaattg ctaatagtca atgaaaatca
     2161 aagtgcaaac tagccacagg ttgctcaaag cacaactttg aggttggaga taaagctgac
     2221 gtggtttgaa gagattttcg aagagtataa aatgaaaaag ggtggcgggg ataaattatc
     2281 ccttgtcgcc accacttgta agtcctgaaa caaagttctt ttgtaggaag aagaagagaa
     2341 tacagattgg aagggcgatg aggatagcac ctgctgagaa gtaggcaatc ttcaagtttt
     2401 tcgcattgtt aacgaaggtt tggagaccta cggcaacagt aaagtattct ttctcacgaa
     2461 gcaagaaact agagaggatg tagtccccga aaggtcccat gaaggcccag agagcttgta
     2521 cggcaaccat tgggcgaaca agtggaagaa caatttgcca gaagcggcgg aagtgtcctg
     2581 caccgtctag ttttgcagat tcgtctaaag acattggcac tgtatcgaag tagcctttca
     2641 tgagccaagc attcatcggg ataccaccac caacgtagag gaagatgagg aaccagttgt
     2701 ggttaagggc gttcaacata agcgccataa cgaagaaggc tgtcaaagcg gccatagttg
     2761 gcaccatttg gatgatcaag aagaagacca aactttgttt acgagccaag aagttgtaac
     2821 ggctgtaagc ataaccagca agtacgatga tacttgtttg aacagccatg gtaattaagg
     2881 cgataatcaa agtgttgagg taccaagtac cgtacaaggt ttcagtgaag aggcctttaa
     2941 agttatcaaa attgaggtcg atattagtat ctagtttaaa ggctgagaca ttacctgctt
     3001 taaaggctga cataatggta atcaacagtg gatagataat tacaattgat agaccaatca
     3061 ggtaaaggta agtaaggctt tgagtcagtc tacgtttgag tttaattgag ttattcatct
     3121 tagacgtcct ccatatcaaa tgcgtgtagt ttcttgaatg cgatcataga gattgagatg
     3181 acaatgatag agataatcaa ggtaacagct gccgccattg agtattgagg agatgtacct
     3241 gttgtcaaac ggtagatcca tgagatcaag atatcggttg aaccagctcc acctccgaca
     3301 ctaccaggtc ctccaccatt gaagaggtac atgatagaga agttgttaaa gttgaaggtg
     3361 tattggctaa tcaaagtagg tgccgcaaca gccaaaatca ttgggaaagt gatgttgcgg
     3421 aatttttgcc aagcgttggc accgtcaata taagctgctt cgtaaaggtc gttaggaata
     3481 gattgcaaga tacccaaagt caaaacgtag atgtatggga atccgagcca accttgcatc
     3541 ataatcaagg caatcttagt ccaagttgga tctgttttcc aaggaataag agctccatca
     3601 aggaaaggaa ggaatttagc caagattggc aatacttgag tgttgatagc accgacacta
     3661 tcgttaaaca tgtttgagaa tgtcaagata gtgatgaagg ctgggacagc ccaaggaaga
     3721 aggaaaataa caccaaagat acgttttcct ttgataaatg gttggttggc aatgatagct
     3781 gtgaagatac caattacgat ttgtaaagta gaagctgcca aagcccaaat gatagtccaa
     3841 gaaagaacag aaccaaaggc agaacgaaag gtactcaagc tccaaatgtt tgtaaagttg
     3901 gtcaaaccaa cccagtccaa caacttgttt ggtggcaaat gttggaagtc atagttggta
     3961 aaggcgatca tcaaggttac gataactggg aagataatcg cgaaggtcat ggcaacataa
     4021 gatggaatga tcaagaggta agggaagcca ttttcataaa tccctttgat catgtctttg
     4081 agtgtgcgtg gaactggaat tccattgtta atgcgttttg caatcgtatg tgcatctttg
     4141 atatttgaga aataaaagag tacataaacg attacaaaga ttagatggaa ggcaccacga
     4201 atcagcataa agagggaatt atcacgacct ggtttgtcac caagagtgat gagattgctc
     4261 aattcagggg ttgcaagtgc taggaagtaa aggacaaata cgatggttac accaaggaag
     4321 ataaaacctt tggctttttg tttattgtaa atctgtccta acccaggaat gatagacagc
     4381 agggctgctt tactaggttg ttgcttttcc atattaactc ctttcatagg atactacttt
     4441 tttataagaa agctaaatta tttgtgtctc tattgataaa ttcaaagggg gatttgattt
     4501 ccacccccct tgaacaaatt ttttattcac caaatttttg tttgattgtt tctttgatca
     4561 atgttacagc atcgttagca gctgttttag catctttttg accacttaca gcatcaaaga
     4621 gcatattttt cgctggatcc caaactgcag acatttgaga gatgtttggc agtggttgag
     4681 tgttcttgaa ctgtttgata acagctgttg tcaactcatc gtttttacct tcagcgtatg
     4741 aacgagcctc agtattagct gggatttcgt tagtcttatc atataatact ttttgttgtt
     4801 cagttgcaac aaggaagtct acaaattttt gagaagcttc aaggttctta acggcttgag
     4861 gaatgaccca agctttacca ccaccgaatg cagcatattc ttttccattt ggaagagttg
     4921 ggatagttgc aactccgtag tttactttag catctttaaa ggcttgagct ttccaaggtc
     4981 cgtcgatgat agcagctgtt ttaccttctt ggaattgagt ttggattaag tttccagcac
     5041 cttctgtatc ttgcatacct ttaggccatt tttcgtacca agatttagcg tagttgatac
     5101 ctgcgataga accgtcgttt gcaagaccga tgtctttagc gtctttaccg ttttggccaa
     5161 agacgtaagc accgttaccg gcaagaagtc catatgtata gtagaagttt gtccagtcag
     5221 ctaggaaggc agtagtttta ccatcttcac cagcgaatgc gtatttgcta tctttagcaa
     5281 ggttttccaa gtcagcaaat gtttttggag catctttcac caagtctttg ttgtagtaca
     5341 taacaagtga ctcgataacg gcaggagcac cgtaaacttt accattagca gctgttacaa
     5401 gagatttagt tgtgtcgtct gttttagcac catcgctcaa tttcacttct gaaagttgtc
     5461 cgtcagaacc aaggctacct acacggtcgt atggagccat cataacatca gggacattac
     5521 cagattggtt gtcaagagaa agtttatcaa gacctcctag agcatcacca gttttaagag
     5581 tgatttttac tccagcttct ttttcataag ctttagcaac ctcttcaata tagctcttat
     5641 atccctcgtc tacatataca gtgagttctt tgacttcaga tgaaccagaa tcagcaggct
     5701 tatcagcagt tttgcttccg caagctacca agagcaagct agcaagtgta acagttccaa
     5761 gcaccgcagt gctcttcata aatttagatg acatagtgta ttcctcccaa agaatagcaa
     5821 gttttattga taaggaaacg caaacgtttt cctttatgag cttagtatag cacaaataga
     5881 aaacggttgc aagtattttt tgtaaaaatt ttaaaaaatt tttaagcttg atttgatagc
     5941 ataattttgc attttaatag aagaaaagta tgaaatagat aagaatacag tatttttaat
     6001 aaaaatatat ggaatctgtc taaagaggga aatcaggagg ggctacctcc ctatttctaa
     6061 tctatatcta ttttctatag acgtttgtgc tttgttgcat ataaattcaa gctccctaag
     6121 gaggttttgt actttgtata ctgtctcgtg agagtcaaac cttaggatta gatagtttta
     6181 agttatcttt gctaaaatga gttagtctcc ttaaaaataa tcaaaaaagt tttttaaaaa
     6241 cgcttgcaat tatgcttgaa aaggagtata cttataagta acgcaaacgt ttgcgtctga
     6301 aaaatacgca acgttccatt attttaacac acgaggtgct attatgaaaa aacgtcaaag
     6361 tggtgtgttg atgcacatct cttctcttcc aggagcttac ggaatcggat catttggtca
     6421 aagtgcttac gacttcgttg atttcttggt ccgtacaaaa caacgttact ggcaaatcct
     6481 tccattagga gcaactagtt acggggattc tccttaccaa tctttctcag ccttcgcagg
     6541 aaacactcat tttatcgatt tagatatctt ggtggagcaa ggtttgttgg aagcaagtga
     6601 ccttgaagga gttgactttg gtagcgatgc gtctgaagtt gactatgcta aaatctacta
     6661 tgcacgtcgt cctcttttag aaaaagcggt gaagcgtttc tttgaagtcg gagatgttaa
     6721 agattttgag aaatttgctc aagacaacca atcatggctt gagctctttg ctgagtatat
     6781 ggctatcaaa gagcattttg acaatcttgc ttggactgaa tggccagatg cagatgctcg
     6841 tgctcgtaaa gcttcagcac ttgaaagcta tcgtgagcaa ttggcagaca agttggttta
     6901 ccaccgtgtg actcaatact tcttcttcca acaatggttg aaattgaaag cttacgctaa
     6961 cgacaaccac atcgaaatcg ttggggacat gccaatctac gtagcggaag attcaagtga
     7021 tatgtgggca aatccacatc tcttcaaaac agatgtcaat ggtaaggcta cttgtatcgc
     7081 aggatgtcca ccagatgagt tttctgtaac tggtcagctt tggggtaacc caatctatga
     7141 ctgggaagca atggacaaag acggctacaa atggtggatt gaacgcttgc gtgaaagctt
     7201 caaaatctac gatatcgttc gtatcgacca cttccgtggc ttcgaatctt attgggaaat
     7261 ccctgctggt tccgatacag cagcacctgg tgagtgggtg aaaggtccag gctacaagct
     7321 ttttgcagcc gttaaggaag aacttggtga gctaaacatc atcgcagaag accttggctt
     7381 catgacagat gaagtgatcg aattgcgtga acgtactggc ttcccaggaa tgaagattct
     7441 tcaatttgcc ttcaacccag aagacgaaag cattgatagc ccacacttgg cacctgctaa
     7501 ctcagttatg tacacaggaa cacacgataa caatacggtt cttggttggt accgtaatga
     7561 gattgatgat gcgactcgtg agtacatggc tcgttacacg aaccgtaaag aatacgaaac
     7621 agtggtacac gctatgcttc gtacagtatt ttcatcagtt agctttatgg caattgcgac
     7681 tatgcaagat ttactagaat tggatgaggc agctcgtatg aacttcccat ctacccttgg
     7741 tggaaactgg tcttggcgta tgactgaaga tcaattgaca ccagctgtcg aggaaggttt
     7801 gcttgacttg acaacaattt atcgccgaat taatgaaaat ttggtagatt taaagaaata
     7861 agacaataat caggagacaa ctaaacatgt tatcactaca agaatttgta caaaatcgtt
     7921 acaataaaac cattgcagaa tgtagcaatg aagagcttta ccttgctctt cttaactaca
     7981 gcaagcttgc aagcagccaa aaaccagtca acactggtaa gaaaaaagtt tactacatct
     8041 cagctgagtt cttgattggt aaactcttgt caaacaactt gattaacctt ggtctttacg
     8101 acgatgttaa aaaagaactt gcagctgcag gtaaagactt gatcgaagtt gaagaagttg
     8161 aattggaacc atctcttggt aatggtggtt tgggacgttt ggctgcctgc tttatcgact
     8221 caattgctac tcttggtttg aatggtgacg gtgttggtct taactaccac tttggtcttt
     8281 tccaacaagt tcttaaaaac aaccaacaag aaacaattcc aaatgcatgg ttgacagagc
     8341 aaaactggtt ggtttgctca agccgtagct accaagtacc atttgcagac tttactttga
     8401 catcaactct ttacgatatt gatgttactg gttatgaaac agcgactaaa aaccgcttgc
     8461 gtttgtttga cttggattca gttgattctt ctattattaa agatggtatc aactttgaca
     8521 agacagatat cgctcgcaac ttgactctct tcctttaccc agatgatagt gaccgtcaag
     8581 gtgaattgct ccgtatcttc caacaatact tcatggtttc aaacggtgcg caattgatca
     8641 tcgacgaagc aatcgaaaaa ggaagcaact tgcatgacct tgctgactac gcagttgtcc
     8701 aaatcaacga tactcaccca tcaatggtga ttcctgaatt gattcgtctt ttaactgcac
     8761 gtggtatcga gcttgacgaa gcaatctcaa ttgttcgtag catgactgcc tacactaacc
     8821 acacaatcct tgctgaagcg cttgaaaaat ggcctcttga attcttgcaa gaagtggttc
     8881 ctcacttggt accaatcatc gaagaattgg accgtcgtgt gaaggcagag tacaaagatc
     8941 cagctgttca aatcatcgat gagagcggac gtgttcacat ggctcacatg gatatccact
     9001 acggatacag tgttaacggg gttgcagcac tccatactga aatcttgaaa aattctgagt
     9061 tgaaagcctt ctacgacctt tacccagaaa agttcaacaa caaaacaaac ggtatcactt
     9121 tccgtcgttg gcttatgcat gctaacccaa gattgtctca ctacttagat gagattcttg
     9181 gagatggttg gcaccatgaa gcagatgagc ttgaaaaact tttgtcttat gaagacaaag
     9241 cagctgtcaa agaaaaattg gaaagcatca aggctcacaa caaacgtaaa ttggctcgtc
     9301 acttgaaaga acaccaaggt gtggaaatca attcaaattc tatctttgat atccaaatca
     9361 aacgtcttca cgagtacaaa cgccaacaaa tgaacgcttt gtacgtgatc cacaaatacc
     9421 ttgacatcaa agctggtaac atccctgctc gtccaatcac aatcttcttt ggtggtaaag
     9481 cagctccagc ctacacaatc gctcaagaca ttatccattt aatcctttgc atgtcagaag
     9541 ttattgctaa cgatccagca gtagctccac acttgcaagt agttatggtt gaaaactaca
     9601 acgttactgc agcaagtttc cttatcccag catgtgatat ctcagaacaa atttcacttg
     9661 cttctaaaga agcttcaggt actggtaaca tgaaattcat gttgaacgga gctttgacac
     9721 ttggtactat ggacggtgct aacgtggaaa tcgctgagtt ggttggagaa gaaaacatct
     9781 acatcttcgg tgaagattca gaaactgtta tcgaccttta cgcaaaagca gcttacaaat
     9841 caagcgaatt ctacgctcgt gaagctatca aaccattggt tgacttcatc gttagtgatg
     9901 cagttcttgc agctggaaac aaagagcgct tggaacgtct ttacaatgaa ttgatcaaca
     9961 aagactggtt catgactctt cttgacttgg aagactacat caaagtcaaa gagcaaatgc
    10021 ttgctgacta cgaagaccgt gacgcatggt tggataaagt catcgttaac atttctaaag
    10081 caggattctt ctcatctgac cgtacaatcg ctcagtataa tgaagacatc tggcacttga
    10141 actaatactc ttcgaaaatc tcttcaaacc acgtcagctt tatctgcaac ctcaaagcgg
    10201 tgctttgagc aacctgcggc tagcttccta gtttgctctt tgattttcat tgagtataag
    10261 atacaaattt atactaatac attttgtaaa aaagcgagtt tcgattgaaa ttcgcttttt
    10321 taaatgctgt ggatttgggt caatcttgtc taaaaatagg gaaatcctag atacagtgaa
    10381 ggctttaaat gctggttttt attgtcttca gccttatatt ttttcgtagt tggttacctc
    10441 atatctcttg tattcgctta cataaagtat tataatataa ttgtaggaaa gaaggtgttt
    10501 ttatgatata cacacttaaa ttggtgttgt ttattacctt tcttgtaata agcttgttac
    10561 ctgataagat ttttggaaaa aataaaaaaa tttggaaaat agtttttgca atattgacgg
    10621 cagtggcagc attgtcattt atgtactaag ttattttaag aatgtaggga aataaaccct
    10681 acattctttt tagttttttc tgttttctaa attctattta tccaagcgat tcaacatttc
    10741 ttgcttcttc gcttcaagtt ctgcacgctt ttcttcgatt tcggcatgtt ttttctcgag
    10801 ttcagaacaa cttgcatcat tgctaaattc ttttcgccat caggagatag ggtgagtcga
    10861 catgtctatt actcacccaa agcagtccta caaagcagga attttctgtt acttttttgg
    10921 aaatagtaac gtttatacag ctttgacact tcgtatcaaa gcgccaaaca cactccgagg
    10981 gatttacaga aagcagaaaa ggaatgatct ggtataagat cattcctttt ctctcttttt
    11041 ctttaagtaa ttatatacaa tgtacgacga agtcgtcatt gcaatgctga tccaccacct
    11101 aaagggaact ttaaacaaca ttgataagat aaagaatata aacaacgaaa atacgttata
    11161 cccaattaat tttattgtat atctcatgat taaaagttaa tccttccgtt gttaggaatg
    11221 gcatcatttt tatcccataa ttgtgctaaa taagtccccg gtgataataa attcatagcg
    11281 gattctaaag caacatcatt tacaaaccaa ctacctagat atctagaaat tgctgaacga
    11341 atagcacttt ttgctgcatg ttttcctttt actttaatta gatttgcaag gcctgcagta
    11401 gttcctccta atgctaaagc tattgtagta tctaatagag cacccatttg attaactgta
    11461 ataccttgcc aagctgctct aaatggagag tatgtaggtg ggattgtata atcgccttgt
    11521 aattgtcggt taattacttc tttgatccat tgttgtgaga cgtctggatg aaaagattgg
    11581 atttcgtttg caagtgtatt gatttgttct tctgttagag aagtgacagg ttgaagttcc
    11641 atatttgttt caatttgcga tacttgttca gaagcgtata cagctgaaac acttggaatc
    11701 gctgatacaa ttaacacaat tgacgtcaaa aaaaacgaaa taaatttcat taatttgttc
    11761 atgagctttt ctccttttta tttgtatctg cttacatttt attatatact gttattatag
    11821 tcaagaaaaa tatgctatta tgttaaaaaa atatttttca aaatataaat ggacggattt
    11881 attttggatt ttatttgtta ttttgacctg cctctatatt ggtaaccatg atttgtttac
    11941 tctcaatcat caagaattct cttttcgtgg tagcgtttgg ggtctggtac tggccttata
    12001 tcacttattg ttcattgata agtttgtaat ttcgaatcga aaataaagat tagagctatg
    12061 cttgactgtg tacttttagg attgattttg gaggaagatt ttgtctctat tatttattat
    12121 tttaaattta tttattttgt ataagatcta ttctttgagg cgggaaaaat cgaaatactt
    12181 gatttatacg gcctatatca tatttggggt aaatgtagta tatggtattc aatggttatt
    12241 aagagaactg atttcaacta tttcccctta atgtgtatgg aaactataac aaaacgcata
    12301 agattaaggt ttgtgtacct gttcttatgc gtttttgtaa tattgaagat tttcggtaag
    12361 ttttatacct ttgggaagtc tagtttagaa tgctttccca accagaatct ctgcttcgat
    12421 ggtaatctct gtcagttggc tccagtcaat cttgctctgg tcaacatgaa agaggagagg
    12481 agtcatactg agtagggctt ggagttgttc tgctgtgata gtcttagtca gagaggcagt
    12541 ttgactagat aggatggtaa agtgttcctg gaaatgctcc ttgatatctt ggttagaata
    12601 ctccttgttt gtcagctggt cctgtactct ttgacggatt tctttgaggt gattttcagt
    12661 tgggataacc tttatcaaga taccgtcttt ggataaaacg cgacgaaatt ctccatagtt
    12721 ggcaggtgag aagatatcaa gcagaatatc catgttagcg tcttttatag gaaggcatgc
    12781 caagtcgcca acgaaccaat tgactgccca gttgggttca cttttagcag cgatttggac
    12841 tgaatctttg gagatgtcaa aggcatagaa agttttttca gagtgacttt cttgtagttt
    12901 gcgagaatag aatccttcac cacaaccgat atccaaaatt gttgtggtag tttttgagct
    12961 tgcaagcaag tcagatacag catctaagat agcttggtaa aagccggctt ctaggatttg
    13021 ttgacggttt tgaaaatttt ccttgtcata gttagcagat tgcttgattt gaggtgctag
    13081 attgacatag ccaaatttcg ccaagtcaaa agaatgacgg ttgcagcact tgaaattagt
    13141 ctctaacaga gtcagatttt cttgacagat aggacaggca aaggcagtcg cagaagcaaa
    13201 acgctgaagt ttgggcttga gatttgtatt catagtttaa gtgtatcaaa agaggcaaat
    13261 gaaagcaact ttaggaataa gtagatggga gattcagtag aaataaaact aattctccaa
    13321 tttatagaat gaaattgctt ttatatctaa attgctatat aataatgata aggaggaaat
    13381 aagtatgtta aaagaagtat taaccgttgc aaaagttgcg aaaaaatctt cattattttt
    13441 gggtggtgtc gcatttggta cccttggttt gaaaatctta gcaagtaagg aagctaaaaa
    13501 aggttattct aaagctttgg ctaaggctta caagttgaaa gacgagctag atgcatctgt
    13561 ttctgttgtg aagcaacatg gagacgatgt cttgcaagat gccaaatatt tgtacgagca
    13621 agagaaaaaa gaagagcaat tagatagcct tataggtgaa taatatgtct tttaaagtgc
    13681 tacatagagg ataccaacat atccgactat catcttcttt ttcacttacc ttggatattc
    13741 aagactatct tcgttccttg gcgagagatg aaaaggggat tgagtctatc cagttttaca
    13801 tggatcaaca gcactttact ctacgcataa aagaaggctt ttctgtatta gataatgcag
    13861 aagccttttt aaaaagaatt gataaaggga aagtttctga gttgatgact cttcccattc
    13921 gtagagaaga gagtgcttat tctattgttt caggtgcagc ggttaagcgt gtactttttc
    13981 gtagttttgt gccgtatcct attcgctata tatggacttg ttatcaggct ttgggttata
    14041 ttagagaagc ctatcaaaca ctagcgcgta aggaactaac gatggaagtc ttggactgtt
    14101 cggctatttt attgtctttg tttatgaacc aatccaagac agctagcaat atcatgttta
    14161 tgcttgattt ggggaatcat ttagatcagt ggtccttgaa aaaaactgca acagatttag
    14221 aacagagtct tcttgcaaaa gagagcgatg tattcctagt acagggcgat acggttgtta
    14281 gtatcaagag ttccgatgtt caaataggag atgtcttgat cttatctcaa ggaaatgaaa
    14341 ttctgtttga tggacaagta gtttcaggtt taggtatggt caacgaaagt tccttgacag
    14401 gagagagttt tccagttgaa aaaagagagt ctgatttggt ttgtgcaaat acagtattag
    14461 aaactggaga gttacgcatt cgtgtaacag ataatcagat gaacagccgt attttacagc
    14521 tgattaagtt gatgaagaaa tctgaagaaa acaagaaaac gaaacaacgc tatttcatca
    14581 agatggcgga taaagtcgtt aaatataatt tcttgggggc tgggctgact tacctattga
    14641 caggttcttt ttctaaggct atttctttcc tattggtcga tttctcctgc gctttgaaaa
    14701 tctctactcc tgtagcttat ttgacagtta tcaaggaagg gttgaaccgt gaaatggtga
    14761 ttaaggatgg agatgttctg gagaaatatc tggaagttga tactttcttg tttgataaga
    14821 caggaacaat cacaactagt tatcctatag ttgaaaaggt gttacctttt ggagactata
    14881 gtgaggaaga tattctcaga atcagtgcct gtcttgagga acacatttat catcctattg
    14941 ctaatgccat cgtcaagcaa gctgagatag agggaattga acatgaggaa atgcatggga
    15001 aactccaata tatcgcaagc aaggggatca aatctcatat agatggccaa ccagttctta
    15061 ttgggaatta tgtcttgatg caggatgagc agattcatat cagttcagaa caaaatgctt
    15121 taattgaaga gtacaagagt cactacaatc tcttattctt ggcttatcaa aatgaattga
    15181 ttggaatgtt ctgcattcat actcctttga gaaaagaagc aaaaacagcc ttggataaac
    15241 ttaaggcaca ggggaaaaaa ttgattctgg caacaggaga caccttgatt aggacagagg
    15301 aattagtcaa agatttgccc tttgatcagg tctatacaga cttgaaacct gatgggaaat
    15361 ttgagttagt agagaaactg cagaaagcag gtcacactat tttgatggtt ggagatggat
    15421 tgaatgactc agcggcttta actctatcag atatcggtgt ggtgatgaat gagagtgcag
    15481 atatttctaa gcagatgagt gatatcttat tgttagataa tcgtttggat ttcttccaag
    15541 agttggattc gttatcatca tctttgcaaa cactcatcaa gaaaaatatt caagataccg
    15601 ttgtcgtaaa tagtagtttg attggctttg gcttatttaa ttggctcagt ccttcaaatc
    15661 tctctatctt acataatcta acaaccttgc gcattgtctt gcgtagcctg tctattaaaa
    15721 atagatagat gagagttatt aacagcaaaa aggagttacc tttctcgagg ttaactcctt
    15781 tgtttataga taaatgttga atagtttagt aagtcaatac aaagtatttt ttcttcccac
    15841 gacggataac agtcagttca ttttctaact tatcagcgtc actcaagaca tagtcaaggt
    15901 cttggatgcg gtcgccgttt acgtagatgg ctccgttttg gacgtcttca cgggcttggc
    15961 gttttgagtt aactatacca gatgagacga gcagttccac gatattgttg tgttcgtctg
    16021 cctgtacttg gtagtttggc acaccacgaa gtccttgttt gagctctttg acagaaaggt
    16081 ttttgatgtt tcctgcaaag agttgctcag tgatgttaag tgcttctttg taggattctt
    16141 ctccgtgaac aagtgtaaca acttcacgag ccaagacttt ttgagccaag cgttcgtgtg
    16201 gcgctgcttc aaattgtttg cgaatatctt caatctcatc aagtgacaag aaagtaaaga
    16261 ttttcaagaa gcgaacagcg tcagcgtcca tcacgttcat ccagaattgg tacatttcgt
    16321 atggagaagt cttttcggga ttgagccaga cggcatttcc ttctgattta ccaaatttct
    16381 taccagttgc atctgtgatt agtggaacag tgataacgtg accagtcttg tccgccttac
    16441 gacgaagcaa ttcggtacca gctgtcatat ttccccactg gtcagaacca ccgatttgaa
    16501 gagtgacatt atggtcttgg ttaaggacga agaagtcata cccttgcatg atttggtaag
    16561 cgaactcagt gtaagaaatt cctgtttcga tccgtttttt aacagattcc ttactcatca
    16621 tgtagttgac cgtgaagtat tttccaatat cacggaggaa gtcaatgaag ctgatgctgc
    16681 caaaccagtc gtagttgttg accatgacag ccttgttttc gccattttca aagtcaagaa
    16741 aacgagaaag ttgtccttgg atagacttga cccagccatc tactgtgtct tttgtttgga
    16801 gactacgttc agcatctttg aaggacggat ctccgatgag acctgtagca ccgccaacga
    16861 gcgcataagg tttgtgacct gctagttgca agcgacgact tgtcaagatt gcgacaaggt
    16921 ggcctaggtg aaggctgtca gcagttggat cgtagccagt atagtaagaa acttgacctt
    16981 cttctagggc tttacgcaaa gcttcttcat cagtcgtttg aaatatcaaa ccacgctctt
    17041 ttagctcatc aaaaatgtgc atgtgtcttt tctccttttt aaaattattg tttctaccta
    17101 ttgtatcaca aacttgggca atagcctagc agaataggga agaaagtggc tattttattg
    17161 aaaatttccc ttttgtggta taatagatag agtgaggaaa tccatgcaaa atcaattaaa
    17221 tgaattaaaa cgaaaaatgc tggaattttt ccagcaaaaa caaaaaaata aaaaatcagc
    17281 tagacctggc aagaaaggtt caagtaccaa aaaatctaaa accttagata agtcagccat
    17341 tttcccagct attttactga gtataaaagc cttatttaac ttactctttg tactcggttt
    17401 tctaggagga atgttgggag ttgggattgc tttggggtac ggagtggcct tatttgacaa
    17461 ggttcgggtg cctcagacag aagaattggt gaatcaggtc aaggacatct cttctatttc
    17521 agagattacc tattcggacg ggacggtgat tgcttccata gagagtgatt tgttgcgcac
    17581 ttctatctca tctgagcaaa tttcggaaaa tctgaagaag gctatcattg cgacagaaga
    17641 tgaacacttt aaagaacata agggtgtagt acccaaggcg gtgattcgtg cgaccttggg
    17701 gaaatttgta ggtttgggtt cctctagtgg gggttcaacc ttgacccagc aactaattaa
    17761 acagcaggtg gttggggatg cgccgacctt ggctcgtaag gcggcagaga ttgtggatgc
    17821 tcttgccttg gaacgcgcca tgaataaaga tgagatttta acgacctatc tcaatgtggc
    17881 tccctttggc cgaaataata agggacagaa tattgcaggg gctcggcaag cagctgaggg
    17941 aattttcggt gtagatgcca gtcagttgac tgttcctcaa gcagcatttt tagcaggact
    18001 tccacagagt cccattactt actctcctta tgaaaatact ggggagttga agagtgatga
    18061 agacctagaa attggcttaa gacgggctaa ggcagttctt tacagtatgt atcgtacagg
    18121 tgcattaagc aaagacgagt attctcagta caaggattat gaccttaaac aggacttttt
    18181 accatcgggc acggttacag gaatttcacg agactattta tactttacaa ctttggcaga
    18241 agctcaagaa cgtatgtatg attatctagc tcagagagac aatgtctccg ctaaggagtt
    18301 gaaaaatgag gcaactcaga agttttatcg agatttggca gccaaggaaa ttgaaaatgg
    18361 tggttataag attactacta ccatagatca gaaaattcat tctgccatgc aaagtgcggt
    18421 tgctgattat ggctatcttt tagacgatgg aacaggtcgt gtagaagtag ggaatgtctt
    18481 gatggacaac caaacaggtg ctattctagg ctttgtaggt ggtcgtaatt atcaagaaaa
    18541 tcaaaataat catgcctttg ataccaaacg ttcgccagct tctactacca agcccttgct
    18601 ggcctacggt attgctattg accagggctt gatgggaagt gaaacgattc tatctaacta
    18661 tccaacaaac tttgctaatg gcaatccgat tatgtatgct aatagcaagg gaacagggat
    18721 gatgaccttg ggagaagctc tgaactattc atggaatatc cctgcttact ggacctatcg
    18781 tatgctccgt gaaaagggtg ttgatgtcaa gggttatatg gaaaagatgg gttacgagat
    18841 tcctgagtac ggtattgaga gcttgccaat gggtggtggt attgaagtca cagttgccca
    18901 gcataccaat ggctatcaga ccttagctaa taatggagtt tatcatcaga agcatgtgat
    18961 ttcaaagatt gaagcagcag atggtagagt ggtgtatgag tatcaggata aaccggttca
    19021 agtctattca aaagctactg cgacgattat gcagggattg ctacgagaag ttctatcttc
    19081 tcgtgtgaca acaaccttca agtctaacct gacttcttta aatcctactc tggctaatgc
    19141 agattggatt gggaagactg gtacaaccaa ccaagacgaa aatatgtggc tcatgctttc
    19201 gacacctaga ttaaccctag gtggctggat tgggcatgat gataatcatt cattgtcacg
    19261 tagagcaggt tattctaata actctaatta catggctcat ctggtaaatg cgattcagca
    19321 agcttcccca agcatttggg ggaacgagcg ctttgcttta gatcctagtg tagtgaaatc
    19381 ggaagtcttg aaatcaacag gtcaaaaacc agggaaggtt tctgttgaag gaaaagaggt
    19441 agaggtcaca ggttcgactg ttaccagcta ttgggctaat aagtcaggag cgccagcgac
    19501 aagttatcgc tttgctattg gcggaagtga tgcggattat cagaatgctt ggtctagtat
    19561 tgtggggagt ctaccaactc catccagctc cagcagttca agtagtagtt ctagcgatag
    19621 cagtaactca agtactacac gaccttcttc ttcaagggcg agacgataat tctctaaatg
    19681 aagtggccaa tcaatggatt gccacttttt tcctttcgtg ttacaataag ggtatgaatc
    19741 agtatcagaa aaagattgtt aacggaaaaa tttattcgct cctatccggc ttaatatggg
    19801 gaatctgtgg aattttagga gagtacttct ttactcatta tcaggtgtct tcgggctgga
    19861 ttacctctat gcgtttgaca ctggcaggga gtcttgtact tatttggtct gcaatacaat
    19921 taaaatcgca agtgctagat atttggcgag acaagaaaaa ttacctgccc tttttagcct
    19981 atgctatttt ggggattttt tcagttcagt attttttcta tctctgtgta gaatactcaa
    20041 atgctacgac agcaactatt ttacagttta ttagccctgt ctttatcctc ttttacaatc
    20101 gcttggttta tcaaaaacga gcgtcaaaaa gcgctgtttt ctatgttttg gttgccatgc
    20161 tgggtgtttg cttgatggcg acaaagggag atctctctca gttatccatg acgccgctag
    20221 ctcttataac aggtttgctg agtgccatgg gtgttatgtt taatgttatc ttgccccaac
    20281 cttttgctaa gcgttatggt tttgttccta cggttgggtg ggggatgatt ttggcaggtt
    20341 tgtttagcaa tgtcctctcg ccggtttatc agctttcctt tactcttgat atttggagta
    20401 tcttgatttg cctcattatc gctttctttg gaacggcttt tgcttttttc atttccatga
    20461 aggctgtgtc cttggtttct cctttggtgg tttccgttat cagtgccagt gaacctctct
    20521 cttctgctct cttgagtgtt ttgttcttag gattagtagt ggattggtcc ttccttctag
    20581 ctatagcctt gattatttta cccatgatat ttttgtctat agaagaagcg aaagaaagta
    20641 gataaaaagt cttttcttaa ttctaaaagt gtgctatact agaatagtca ataaaacacg
    20701 gggagatagt tgtgaagagt gtttttaggt tgtatcggta ggggcttgct tttaccgaca
    20761 gcacgtttta tctcacatcc ctaaaaaatc atacctaaaa acagacaaaa aggtttcaaa
    20821 tttgaggcct tttttggtag aataggtatc attataacga accaggaggc acctatgact
    20881 gctacaaaaa tgaacgctca agaaattatc caatttatcg ccaatgctga aaagaaaacc
    20941 agtgtcaaag taacctttga ggggcaactc gcaactgctg tgcctagctc tgttgtcaaa
    21001 ctagggaatg tcctattcgg ggattggaag gacgtggctc cgcttcttga aggtttagta
    21061 gaaaatcaag attatgttgt cgagcaagat gctcgtaatt ctgcagttcc tttgctagat
    21121 aagcgtgcta tcaacgctcg tatcgagcca ggtgctatta tccgtgacca ggtggaaatt
    21181 ggtgacaatg ttgttatcat gatgggagct gttatcaata tcggtgctga aatcggtgct
    21241 ggaaccatga ttgacatggg tgccatcctt ggtggccgtg ccatcgttgg aaaaaatagc
    21301 cacgttggtg caggtgcagt tttggcaggt gtgattgagc cagctagtgc tgaaccagtc
    21361 cgtgtcggag acaatgttct catcggggct aatgcagtgg ttatcgaagg agtccaaatc
    21421 ggtagtggtt cagttgtcgc agcaggagct attgttaccc aagatgtccc agaaaacgtg
    21481 gtagtagcag gtgttccagc tcgtattatc aaagaaattg atgcccaaac tcaacaaaaa
    21541 acagcgctag aggatgcgct tcgtaccttg taattgtaaa agtaaaaaag aggcggaacc
    21601 ctttttccag cctctttctg ctatatcgga ggacagatag atgttagatt tgattcagac
    21661 tagacgagat ttacaccaga ttccagagat tggcttggag gagttcaaga ctcaggctta
    21721 tttgctggat gtgattgaga aattgactac gggcaaggat tttgttcaaa ttcgtacttg
    21781 gcggacaggg attttggtct acctgcaggg aagtcagccg gagcgaacca ttggttggcg
    21841 gacagatatt gatggcctgc ctatcgtcga acaaacaggt ctaccttttg cttctcaaca
    21901 ccaaggtcgc atgcatgcct gtggccatga ttttcatatg accattgcct taggctgtct
    21961 tgagcgcgcc cttgaggagc aacctaaaaa taatctgctc tttctatttc agcctgctga
    22021 agaaaatgaa gctggtggta tgctcatgta tgaggctggt gcttttggag attggttgcc
    22081 agatcaattt tatggcctcc atgtccgtcc agatttgaaa gtcggccaga ttgcgactaa
    22141 tactcataca ctctttgcag gaacttgcga ggtgaagatc cgtttcaaag gtaaaggtgg
    22201 ccacgcggct tttcctcatg aagccaatga cgccttggtg gcggctagtt actttgtgac
    22261 ccaagtgcag tcagttgtta gccgcaatgt caacccaatc gagggagcag tggtgacctt
    22321 cggcgttttt caagctggaa ccaccaacaa tgtcatcaca gacacagctt ttttacatgg
    22381 aactattcgt gccttgacac aggacatgag tctcttggtg caaaagaggg taaaaacagt
    22441 tgcagaaggg gttgcagctg cctttgatat ggaagtcgaa gtggaactca aacaaggtgg
    22501 atacctacct gttgagaaca atccagcctt ggcgcgtgaa ctgatggact tctttgacga
    22561 aaaagacgga atcgagttga ttgatatcga acctgctatg acaggcgagg actttggtta
    22621 tctcctttca aaggttgatg gcgtgatgtt ttggctaggt atcgatagtc cctacgctct
    22681 tcatcaccct caaatgagtc ctaaggaaga agtcttagct attggggtgg ctgcggtgtc
    22741 tagtttcctg aaaaagaagg cagcagaata gagggcttgt ctatgaaatc ggaattacgc
    22801 aagcaagtct tgcaaggaat gaaggctata tctcaagaac aaaaacagtt tatagatcaa
    22861 actttaaccg agcggctttt acaccatccc ttctatcaag aagccaaggt catcgcaacc
    22921 tatctctctt ttcctcatga gtttcaaacg caggaactga ttgagcaggc gctgaaggac
    22981 ggcaagaagg ttttaatacc caaaacttat cccaaggggc gcatggactt tgtggtctat
    23041 gatccgcaac agttggtaaa aacttccttt ggattactgg agccacaggg agatttggaa
    23101 gtggtggatg catctcagat tgatttgatt catgttcctg gcctggcttt tacgacaaaa
    23161 ggatatcgga taggatacgg tggaggctat tatgaccgct atctggaaca tttttctggt
    23221 catactttga gtacggttca tccttgtcaa attcaggact ttatacctga aaaccatgat
    23281 attcctgttc aggaggtatt aattgatgaa ggaaatcttt gatagacgtt accctgtgac
    23341 gagtttcttc ctcttagtga cggccttggt atttttacta atgttggtca ctgcaggcgg
    23401 aaactttgac agggcagata cattatttcg atttggagcc atgtatgggc cagctattcg
    23461 cctctttccc gagcaggttt ggcgtctctt gtctgccatt tttgttcata ttgggtggga
    23521 acatttcatt gttaatatgc tttcacttta ttatcttgga aggcaggtag aggagatttt
    23581 cggttctaag cagtttttct ttctctatct tttatcagga atgatgggca atctctttgt
    23641 ttttgtattt agtcctaaat ccttagcagc aggcgcctct acctctcttt atgggctatt
    23701 tgccgcgatt atcattcttc gctatgcaac tcgcaatcct tatatccaac agctagggca
    23761 atcttatctg acactttttg tggttaacat tattggaagt gttctgattc caggaatcag
    23821 cctagcaggc catatcggtg gtgcagttgg tggcgcattt ctagcagtta tctttccagt
    23881 tagaggagaa aaacggatgt ataacaccag ccagagatta ggagcggtag tcttgttcgt
    23941 aggactcgcc attttgcttt tctacaaggg aatgggaatg tgacgaagtt gaaagaaaat
    24001 ttgtgtaatg aaaaaagata aggcattttt tgaaccttat ctttttattt tattccttct
    24061 cagtcaattc ttttccaagt tggatgaggt aattcttcaa atcatctttg acttgtggat
    24121 gtttgagggc gtagtcaata gatgttttca taaagccaaa cttatcccca acgtcgtaac
    24181 gagctcctgt aaattcacgg gcaaaaacac gctgtgtttt attaagagta tcgattgcat
    24241 cagtaagttg gatttcattc ccagcaccag gagcttgctt ttcgagaatc tcaaaaattt
    24301 caggcgtgag gaggtagcgt ccgataatag caaggtcgct aggagcgtcc tctggagctg
    24361 gtttttcaac aaaggtttca acactgtaaa gaccatcttt tccttcgcct tgcggagcaa
    24421 taaccccgta agcagatact tcgtcatgag ggactggcat gacagcgata gtagacgcgt
    24481 gggtacgctc gtagtcatcc atgagttgtt tggtaagtgg aacagccttt tcgtctgtga
    24541 tatccatcaa gtcatcacca agcataacga caaaaggttc atttccgacg aaagccttgg
    24601 cttgcaaaac agcatctccg agaccgcgtg gatgagtttg gcggataaaa tgcagacgca
    24661 tgccagttgt ttcatcaact agcttcaaaa gatctgtttt ccctttttct ttgaggttat
    24721 attccaattc gaagtttgaa tcgaagtggt cctcaataga acgttttgat ttaccagtga
    24781 caactagaat atcttcaata cctgatttga gagcctcttc cacgataaac tggatagttg
    24841 gtttgtctac gattggcaac atttctttgg caagggcctt ggttgctggt aaaaatcgag
    24901 ttcctagtcc agcagcaggg ataactgcct ttctaacttt tgatgtcata aaaatccttt
    24961 ctatagaggg ttaagaccac tcattttctg ctttaaattc attgttcatg atgtcataaa
    25021 tggcatcttt gatattggtt ccgtgataaa taacttggta aatagcctgt gtaatgggca
    25081 tatagactcc aagttcttgg gctagttcat aggctgctcg agtcgttgaa attccttcga
    25141 ttaccatgcc catattagct tctatatcag ctagggattc tcctcgtccg agagcatctc
    25201 cagctctcca gttacgagag tggatggaag ttcctgttac gattaaatct cccacaccag
    25261 ataagccgct ataggtcaat ggactggccc cgagtgctac ccctaggcgg gtgatttctg
    25321 ctaaacctcg agcgatgatg gctgccttag cattatcacc aaatccaaga ccatgtaaag
    25381 ctccagcacc gacagcaata atatttttaa gagcaccagc agtttcaacc ccgataacat
    25441 ccgtattggt ataaagtcgg aagtagtgat tactaaatag ctcctgaacg tattgagctg
    25501 tttgtaaatc tttagaagca gcagttatta aagttaggtc acgcacaatg gtctcttctg
    25561 catgactagg ccctgaaaca acgacgatat cactacggag atgttcagga atttcttctt
    25621 caagaatggt tgataatcgt ttatggctat caggttctaa tccctttgat gcgtgcatga
    25681 tgataacctt atggtccaag gtttgtgcaa cttgctgggc aacaagtcgt gtcacttttg
    25741 ttgggacaac aaacaaaatc gcatccacat ttttcaatgt ttctgctaag tcggtgtagg
    25801 caatgatatt ttcgtctaga acgacatctt taaagtagtg cttattagta tggtgtgtat
    25861 taatttcatt gatttgctcg ggaagatttc cccaaatacg tacctcgtgt ccattgtcat
    25921 ttaagacttg tgaaagggcg gttccccaag aaccaggccc caagacggcg acggtttgtt
    25981 tttccatgat ttcctccttg atagagttct ttctcttatt ctatcatatt ctaggggatt
    26041 ttgcacttgc attactgggg tatggtggaa aaatacacaa aaaccgagat gaagggataa
    26101 actcttagtc tttagttaaa gtgagaagaa atctgataga tagtttgatt cagtatatgc
    26161 tataaataga ggtaaacaac tcaggaggtt cttgtaggtt gcgagagttt ggcgaaaaaa
    26221 ttaaaagatt acgtttggct aaaaaaatca gtcgttcaga attttgtggt gatgagtctg
    26281 aattaagtat ccgtcaatta attagaattg aaaatggaga atccagacca acactaacaa
    26341 agttaaaata tatcgctgaa cgtttggggg ttgaagatta caagttgatg ccaagttata
    26401 tagagttgga taaggaatac ctagaattga agtatttctt gatgaggact cctacatacg
    26461 aagatgaaac tatcgcccaa aagaaagaga gcgttttgat aagatttttg aagagtatta
    26521 tgataggcta cctgaggaag aaagatttat catcccaaat tattcatatc tggcactaac
    26581 gaactacaca gttcaaaaat taccagaaaa gctagttgaa atactgtcct tctggtgatt
    26641 ttgcttaatt tctgatgttc gagacatgat tgaggagatt tgtcttgatt ttttcctaaa
    26701 aaagggcaga ctcctccctt ggtttgatgc tcgattttta aagtaaggtg acttattctg
    26761 ttaggcatgt tttcccctgc cctctagctc tatatggaac agggagtatc agatttatct
    26821 ggcagattgt atcaaataag gcttaaaact gttttgaata ggcatataga cttgagaatt
    26881 tgagaatatg tcgtctagca gtagagacat attttccggc aatatgaagg aagagacgtc
    26941 gaaaacgctt gatagtcaag gcctttactt catcaccagc tagctgcttt aaaaagaggt
    27001 agagattata agccagacag cccatcatca tacgtacttc attcttaatc atggtcgaac
    27061 tatctgtctt atccccaaag aatcctgctt tcctttcttt gataaagttt tcagcattcc
    27121 ctcgttcacg atagaattga aacagctcct cactatctac actgcttaaa ttgttcaaat
    27181 gaactttttt acaaccataa aaaagagcac ttaatcgtac tcttctcttt taaggattag
    27241 ttgaattaat tcaaatccac tagttctcct gtttctaggt agactaggcg ttcacaaatg
    27301 ttagcaatgt aatcagcgaa gcgttccaga tgccctatga tataaaggta ttgtgttcca
    27361 ttgggaattg aggtttcttg gtctttcata agtccaatga tttcctttga taaggcataa
    27421 taatattggt caatctgttc atctttttga gcaatactaa tagcttttga ggcttggtgc
    27481 aaaggaaagg caaccaacaa atcggctagc atgctgaggg ataatttacc catttggtgt
    27541 aactgttctt cgtcaggggc tagttgattt tcttttagtt gcaaaacagc tttggcaatg
    27601 cctgccatat ggtctcccat acgttcaagg tctgaacaag aagacatgat gctaattaca
    27661 aatcgaaggt cagacacttg tggctgctgc aaggctaaca aacgggcaca ggccaattcg
    27721 atagcgcttt gaccttggtt gatagcatga tccttattga taattagctc tgccatctcc
    27781 ttgtctttgg aggctaaggc cagtaaggct tttgaagctg tttcaaggac aagttgccct
    27841 agtcctaaaa aggattgttc taattcatgc aattctaagt caaattgatt tctcataggt
    27901 ttttccttcc ttatccgaac cgtcctgaaa tatagtcttc tgtgcgctga tcttttggat
    27961 tggtaaacac gtcaacggta tctccaaatt cgcaaatttc tcctgttaag aaaaaagcag
    28021 ttttatctga aatacgtgaa gcttgttgca tgttatgggt aacaatgata atcgtataat
    28081 ccttttttag ttgctgaatg aggtcttcaa tttttaaagt ggagataggg tctaaggctg
    28141 aagtcggctc atccattaac agaatatcag gttctactgc taaagctcgc gcaatgcaaa
    28201 ggcgttgctg ctgaccgcca gataaggaca tggcactctt tttaagatca tctttgactt
    28261 cttcccaaat ggctgcccct tttaaagatt tctccactaa ggcatctaat tgttttttgt
    28321 ctcgaatacc atgtgtcctt ggaccataag ccacgttatc atagatagac atggcaaagg
    28381 gattaggctg ttgaaaaacc atccctacac gcttgcgtag ctgattaagg ttgaatttgc
    28441 tactataaat atcttgctca tctaagagga cttggccttc aatatggcaa gaaggaacca
    28501 aatcgttcat ccgattaagg gtttttagaa aagttgattt gccacaacca gatgggccta
    28561 tcaaggcagt aatctgtctt tctggtaatt gaatcgaaat attttttaag gcttgaaaat
    28621 ccccgtaaaa taagtctagg tgtctaactg aaaatgttcc catactagga agctcctttc
    28681 acaagtttcc gagataataa gcttgataga gtatttatca ttaaaacagt aataatcaaa
    28741 atcacgccgg tagcataggc ttcattgaca tgtagcccct cacttgacag catatacata
    28801 tgtagggcta gagaacggcc tgaagacatg agactacttg gcgtattggt agaggtacct
    28861 aatgtataca tgagggcagc tgtttcacca acgatacggc caatagctag tatcactcca
    28921 gctaaaatac ctggcatggc aactggtaga acaattctaa aaacagtccg taacttacct
    28981 gccccaagtc cataacttgc ttgacgcata ctatcactaa cagataaaag ggcttcttct
    29041 gttgagcgaa taatgactgg caacaccatg ataactgagg ttaagattcc tgataacaga
    29101 gagtattgaa aacctaagaa gactacaaag aagagcatgc caaacagacc aaaaacaatg
    29161 gaaggaatcc cagataaggt atctgaggcc aatcgcatga ttttaacaca aagggaatct
    29221 ttttttgtat attccacaag ataaaaacca gcaaaaatcc ctatgggcaa ggctaaaaga
    29281 agagcaccaa agaccagaat aacggtggaa ataatcgctg gcataaggga aatgttctca
    29341 gaagtataag tccaagaaaa gagggataga cttagatgag gtaagccttt gatgaggata
    29401 aaaccaatga ttaaaaagag agagccaaag gttaaagctg aaaaacaata aacgagaagt
    29461 tttagcaggt atttactcat aagatgattt tcctttcaag taggcaaagt aggcattaat
    29521 caagagaata aggaaaaaga gaactgctga ggttgcaata agggcttccc tatgctgacc
    29581 tgatgcgtaa gccatttcca gaacaatatt ggttgttaag gttctggttc ctgaaaagag
    29641 tccacttgga ataatcggct ggttgcctgc caccaaaata actgccatgg tttcacctac
    29701 tgcgcgaccg attcctaaaa taactgctga taaaatacca gatctcgcag ctggcaagat
    29761 gacactaaaa atactccgtt catgactagc tcctagagcc aagctaccag aataatacgt
    29821 tttgggaact gttcggatag cagattctga caaactgata atggttggca aaatcattat
    29881 tcctaatagt aacgaagcgg ttaggacact catgccattt cctaaaaagc ttctaatcca
    29941 aggcaccaat aattgtaggc cgaaaaaacc ataaacaata gatggaatgg ctgccatcaa
    30001 gttgatagct gattttaaga agccatagac gggctttgga caataataaa ccataaacac
    30061 cgatgtcaag atgcctgttg gcaccccaat cacaatcgct cctaaggtaa ttaataagga
    30121 accaacgatc attggtaaaa taccatagct tgccggaatg ttcgttggcg accaatcact
    30181 gcctaataaa aaacgggcaa agccgtagtt agccatgaaa ggtaagccat tactaaaaat
    30241 aaagaaacag attagcaaaa tagctacaac agctactgtt gcactcatga aaaaaattgc
    30301 cctaaaaact gcttctttga aggcttgttt tatcacatct tgtcctttct agtgaagaaa
    30361 gtaagggaga tacgacacct ccctacttgc cttctttatc ttattgtacg atgaaacgtc
    30421 tgcatctctt tagagattta tggagcaaac attttattta atcttgtccc aggtggttaa
    30481 tttaccacta aaaacgtctg caagttcagc catactgact tggcttgcct tattgtcatt
    30541 attgaccaca acagcaatac cgtctaaagc aatagcatca tgggtgagac tcttaccttc
    30601 ttcaggagtt aattccctag aaaccatacc aatatcagcg gttttctcct taacagcggt
    30661 aatacctgct gaagacccat tagaggtaat atcaatcgta acttctggat tttctttttt
    30721 ataagcttct gctaattttt ccattaaaga agatactgaa gtggaaccta caacagacaa
    30781 cttgcctgat aagtgttggc ttgtatattc tgtggtttca gttttagctt caataaattt
    30841 attatctgtg accacttgtt gaccttgttt ggagtggata aagctgataa aatcttgacc
    30901 tagcttggaa agattagaag accaaacaat gttgaaggga cgttgaagag ggtattcacc
    30961 atctaaaact gtgtctcgac tagccttgac accatcaatc tctaaagcct tgacagattt
    31021 cgttaaagat cccaaggaga tgtagccgat agcattagca ttcccttgaa ctgctgagag
    31081 aacaccttct gtactatttt gaatcacagc tgttttggca gtgttgtcaa tttttttatc
    31141 accgtctttt ttgagaatcc ctgtgatttc tgtgaaggca ccccgtgttc cagagccatt
    31201 ttctcgtgaa atcacctcaa tcgttcctga agctgactgt ttggaagcag ctgactgatt
    31261 gccacaggca acaagcccaa atcctgataa gccaatggct gcaagagtaa gcattttttt
    31321 gaatttcata ataatcacct ttatctctat gtatttttct tgtgtaggct tactacattt
    31381 atagtctaac aagtctttgt aaaggtttat ccctgattca tgtaaagatt gtgtaaagaa
    31441 tcaaaaaaag ccacttttga aaaatggctg ctcctaaaaa tagctttaaa aattattagt
    31501 cctgtgcgaa agattggtta ggaagaaaaa tcgtgaagca actgcctctg ccaagctgac
    31561 ttgtcaccgt gacttggcca cctaataatt gactgagttc tttgacaatg gcaaggccaa
    31621 gaccagtgcc accagtttgt ctgcttcgac ctttattaac tcggtaaaaa cgttcaaaaa
    31681 tacgctcctg ctctaattga ctaataccaa tccctgtatc tgatacagaa atcttaatgc
    31741 cttcgttcac cttttgggtc ttgacctcaa tttttccccc ttgttcagtg taacggatgg
    31801 cattggataa aagattgagt aagatttggg aaagtaattg actatctgat acgagggtga
    31861 catcatctgg cacctgcacc tttagctgta aatccttctt cttgagctga ggttgcaagc
    31921 tttgagtcaa atcctgtaca aattctgcca aagaaagggt cgtccattgt ataggcattt
    31981 gttgagcctt agataaggta agaagatgct caacaatatg ctcaagacgc aagctttctt
    32041 tgtaaataat gtctagaaag tcatccttga gcgcttcttc ttcagctgac atccccttaa
    32101 tggtttcagc aaagccctta atcgaagtaa ctggtgtcct caattcatgg gaggcatttg
    32161 agacaaaggc taaatttaac ttttcataag ttctaatcgt tgttaaatca tatagcaaga
    32221 cgagcacagc ttccacagat tgggtggggc taaaaacggg aactgctgtc acttctaaaa
    32281 tcaagtcacc ctcatgaaac ccacttactt cttgttttaa ccttgttttt tgatcaaagg
    32341 cttggtgaac taaatttcga atatccatcc gtttgaggtc atcaagtgaa cttatgtcgc
    32401 cgtccacatc gggaaaataa tgaggcagag agcgactgga taataacatc tgaccttgag
    32461 cggaaactaa aaacgtcccc atggttaggt gcgacagaag aacctccatt gtttcggcta
    32521 ggtccttgta ttgctgatcc tgttgggaga ctttggtttt taggccagac acatactgag
    32581 ccaaagactt taagtcttct tgcccttttt ctaaaaagta ttcactactg gtcaagagag
    32641 gttggtgcaa ggtctcaaaa gcaacttccc atttccaaag gcaaaagagc cagtagccac
    32701 cttgtcccaa agaaagggct agaagaaaga gaccgatgcc tttactgatc caagttaatg
    32761 ccatccctgc aatcagaatg aggctaacac ttagattgac tagccaaaat tgaaggtagc
    32821 gtttcatcta taactccttg aacttataac cataaccccg aatggttcga ataaattgag
    32881 gggctttagg attgtcttca attttttccc tcaacttacc aatatgaacg tccaccaaac
    32941 gtgtttcctg cccaaagtca tacccccaga tacgttccaa aagacgctct ctagtcagtg
    33001 tcatgttggg atgtttcata agatagagca agagttcaaa ttcttttggg gtcaaactca
    33061 gtaacttatt cgccttgtag acttcatgac gctcagggta tactttcaag gtcccaaata
    33121 gccaagaatc gtcagcgata ttatctgaat catctccttc ttgttctcct ttagttcgcc
    33181 tgaggacagc cttgacacgc gccagcaatt ctctagggct aaaaggcttg gtcaggtagt
    33241 catcagcccc taattccaag gccaaaacct tatcaaattc atcacttttc gcagaaacca
    33301 tcataattgg agttttgacg cctttggctc tcagccgctt acaaacttcc atgccatcta
    33361 attgtggtaa catgatatca agcaagataa aatcaaaggg ttctgtttct gccaaagcta
    33421 aggccttccg tccatttgtt accaattgag tagaaaagcc ttccttactt aaatggtagt
    33481 caagcaattt cagaatgtgt tcttcatcat ccactaataa gacttgtttt gtcatctatt
    33541 atctcctatt ggtaacatta taacacaatt atcagaaatc ctaacattgc taaattagat
    33601 taaatttgct tatcaagact agtatctggt caaatgctca atcatctcct tgtgctctgg
    33661 ataggtcgcc agtagatctg ccctttcaaa taattcaaaa tcctcaaatt caaaaccagg
    33721 agcaacaaga caagaaacca gagcataatc cttatcaact gttgatcccc aaatagtgcc
    33781 cttaggaaca cagtagtgaa gttgttgccc tttggatatg tccaggccta aagtgactgc
    33841 ttcgtagtga ccatctgctg taatcatgtg aacagtaagt ggggatcctg catgaaaata
    33901 ccagatttca tctgctgtca atcggtgaaa atgtgaagga ttcgtttctt ctaataagaa
    33961 ataaatactg gtataaagcg cccttccctt accagcaagg tttatagtgt ctgaagcttt
    34021 ttttgtttgt ctaaaatagc caccttcaat atggggagct aactctagag ttcttatcaa
    34081 gtcttcttta tccgtcggag ccaatgggtt gaagtaactc ttgttcaaag tggttttacg
    34141 atttcaagaa ctcctctcag ttctgaggac acggtaatga ttgatgcgac ggaagtacaa
    34201 atcaatcgcc ctaaaaaaag aattagcgaa ttattctggt aaaaaaaatg ccacgctatg
    34261 aaggctcaag cgattgtcac aagtcaaggg agaattgttt ctttggatat cgctgtgaac
    34321 tattgtcatg atatgaagtt gttcaaaatg agtcgcagaa atatcggaca agctggtaaa
    34381 atcttggctg acagtggtta tcaagggctc atgaagatat atcctcaagc acaaactcca
    34441 cgtaaatcca gcaaactcaa gccactaaca gttgaagata aagcctataa ccatgcgcta
    34501 tccaaggaga gaagcaaggt tgagaacatc tttgccaaag taaaaacgtt taaaatgatt
    34561 tcaacaacct atcgaaatca tcgtaaacac ttcggattac gaatgaattt gattgctggc
    34621 attatcaatc atgaactagg attctagttt tgcaggaagt ctattatttg gttaggtgaa
    34681 ttagtgaagc gtttaggcaa gtgtctctgg ttacgacgtc atggactcta aatcgattat
    34741 atttaggggt catgactagt gaagcagtta gctagttcgc atataagcgg ctagcgtcta
    34801 acaattagga actttagttc caataacttt aagattacga cgttttagga cataaatcga
    34861 tcatatttat gtcctaaaac tagtgaagcg cctagccaaa gtccgaatag gatttggcgt
    34921 tagttactta gattgctttg caatcaagta actttggcga tttacatctt ctctggcgct
    34981 tctactccaa gcaagcgaag ggcttctttg agaacgactg cggttgcgta gctgagggct
    35041 agacggctgt cgcgttctgg gctttcatcc aagatacgtg tatgtgcata gtatttgtta
    35101 aaggattgag ccaggctaat tgcaaattta gcaatgatag aaggttcaaa gttatctgcc
    35161 gcacggttga taatacgtgg gaagtcttga atgagtttaa tgatttccca gctttcagta
    35221 tcattcaagc tatagttgcc agctgtttct ggtttgaaat cggctttgcg taagatagat
    35281 tggatacgag cgtaggcata ttgaacgtaa ggtccagttt caccctcgaa ggataccata
    35341 gcttctaggt cgaagtcgta tccatttgta cggtcagttt tgaggtcata gaatttaatg
    35401 gctccaaccc caacagcatg tgctacttgg tctttgtttt ctagttcagg atttttagcc
    35461 tcgatttgga ccttggcacg gctaacagcc tctgcaacag taggctctag caagatgaca
    35521 ttccctttac gagtagagag cttcttccct tcttttgtaa ccagaccaaa aggaacgtgg
    35581 gtaatgtcgt cactccaatc gtagcccatc tcttgcaaga cagctttgag ttgtttaaag
    35641 tgggcagatt gctcttgacc aacgacgtag atagatttag caaattggta ttcattttta
    35701 cggtagaggg ctgcagccaa gtcacgtgtg atatagagag ttgcaccatc agacttcttg
    35761 atgagggctg gatgttcaat tccatatttc tcaagattca caacttgggc accttctgat
    35821 tcaagaagta gtcctttttc agaaagaatg tctacaactg catccatctt atcattgtag
    35881 aaggcttctc cgttatagct gtcaaattca accttcaatt cattgtaaag gcggttaaat
    35941 tccactaaac tttcatcgcg gaaccattgc caaagagcga gagcttcctc atctccattt
    36001 tcaagtttac ggaaccattc gcgcgcttct tcatccaagc tagggtcatt ttcagcttca
    36061 gcgttgatgc ggacatagag tttaaggagt tcatcgattg gatgagcttt tacagcttct
    36121 tcgtcgcccc attttttgta ggcaacaatc aacatcccaa attgtttacc ccagtctccc
    36181 aaatggttga ccttgaccgt ttgataaccg attttttgga aaatatgtga caagctatct
    36241 ccgataacag ttgaacgcag gtggccaata gaaaatggtt tagcgatatt cggactagac
    36301 atgtcgataa caacattttc ttgtttgcca atattttggt cagcatagtg ttctttttca
    36361 gtggtaacag cttgcaatac ttgagcagaa atggcagatt tatcaaggaa aaagttaacg
    36421 taaggtcctg ttgcgacaac tttttcaaag gcttggctgt tcattttttc agccagttca
    36481 gccgcaatca tttgtggtgc tttacgttcg actttggcaa gagaaaaagc agggaaagcg
    36541 atgtcaccca tttctgagtt tttaggggtt tccagtaact ttaaaatagc ctcttggtcc
    36601 aggctatcaa tgatgctagc caattcgcta gcaatcaatt cttttgtatt cattaagagc
    36661 tcctttttgg acttttctac tattttatca caattttaaa gaaagaagaa aaaatttttg
    36721 aaatctcctg tttttttggt ataatatggt tataaatata gttataaata tgcacgcaag
    36781 aggattttat gagaaaaaga gatcgtcatc agttaataaa aaaaatgatt actgaggaga
    36841 aattaagtac acaaaaagaa attcaagatc ggttggaggc gcacaatgtt tgtgtgacgc
    36901 agacaacctt gtctcgtgat ttgcgcgaaa tcggcttgac caaggtcaag aaaaatgata
    36961 tggtgtatta tgtactagta aatgagacag aaaagattga tttggtggaa tttttgtctc
    37021 atcatttaga aggtgttgca agagcagagt ttaccttggt gcttcatacc aaattgggag
    37081 aagcctctgt tttggcaaat attgtagatg taaacaagga taaatggatt ttaggaacag
    37141 ttgctggtgc caatacctta ttggttattt gtcgagatca gcacgttgcc aaactcatgg
    37201 aagatcgttt gctagatttg atgaaagata agtaaggtct tgggagttgc tctcaagact
    37261 tatttttgaa aaggagagac agaaaatggc gatagaaaag ctatcacccg gcatgcaaca
    37321 gtatgtggat attaaaaagc aatatccaga tgcttttttg ctctttcgga tgggtgattt
    37381 ttatgaatta ttttatgagg atgcggtcaa tgctgcgcag attctggaaa tttccttaac
    37441 gagtcgcaac aagaatgccg acaatccgat ccctatggcg ggtgttccct atcattctgc
    37501 ccaacagtat atcgatgtct tgattgagca gggttataag gtggctatcg cagagcagat
    37561 ggaagatcct aaacaagcag ttggggttgt taaacgagag gttgttcagg tcattacgcc
    37621 agggacagtg gtcgatagca gtaagccgga cagtcagaat aattttttgg tttccataga
    37681 ccgcgaaggc aatcaatttg gcctagctta tatggatttg gtgacgggtg acttttatgt
    37741 gacaggtctt ttggatttca cgctggtttg tggggaaatc cgtaacctca aggctcgaga
    37801 agtggtgttg ggttatgact tgtctgagga agaagaacaa atcctcagcc gccagatgaa
    37861 tctggtactc tcttatgaaa aagaaagctt tgaagacctt catttattgg atttgcgatt
    37921 ggcaacggtg gagcaaacgg catctagtaa gctgctccag tatgttcatc ggactcagat
    37981 gagggaattg aaccacctca aacctgttat ccgctacgaa attaaggatt tcttgcagat
    38041 ggattatgcg accaaggcta gtctggattt ggttgagaat gctcgctcag gtaagaaaca
    38101 aggcagtctt ttctggcttt tggatgaaac caaaacggct atggggatgc gtctcttgcg
    38161 ttcttggatt catcgcccct tgattgataa ggaacgaatc gtccaacgtc aagaagtagt
    38221 gcaggtcttt ctcgaccatt tctttgagcg tagtgacttg acagacagtc tcaagggtgt
    38281 ttatgacatt gagcgcttgg ctagtcgtgt ttcttttggc aaaaccaatc caaaggatct
    38341 cttgcagttg gcgactacct tgtctagtgt gccacggatt cgtgcgattt tagaagggat
    38401 ggagcaacct actctagcct atctcatcgc acaactggat gcaatccctg agttggagag
    38461 tttgattagc gcagcgattg ctcctgaagc tcctcatgtg attacagatg ggggaattat
    38521 ccggactgga tttgatgaga ctttagacaa gtatcgttgc gttctcagag aagggactag
    38581 ctggattgct gagattgagg ctaaggagcg agaaaactct ggtatcagca cgctcaagat
    38641 tgactacaat aaaaaggatg gctactattt tcatgtgacc aattcgcaac tgggaaatgt
    38701 gccagcccac tttttccgca aggcgacgct gaaaaactca gaacgctttg gaaccgaaga
    38761 attagcccgt atcgagggag atatgcttga ggcgcgtgag aagtcagcca acctcgaata
    38821 cgaaatattt atgcgcattc gtgaagaggt cggcaagtac atccagcgtt tacaagctct
    38881 agcccaagga attgcgacgg ttgatgtctt acagagtctg gcggttgtgg ctgaaaccca
    38941 gcatttgatt cgacctgagt ttggtgacga ttcacaaatt gatatccgga aagggcgcca
    39001 tgctgtcgtt gaaaaggtta tgggggctca gacctatatt ccaaatacga ttcagatggc
    39061 agaagatacc agtattcaac tggttacagg gccaaacatg agtgggaagt ctacctatat
    39121 gcgtcagtta gccatgacgg cggttatggc ccagctgggt tcctatgttc ctgctgaaag
    39181 cgcccattta ccgatttttg atgcgatttt tacccgtatc ggagcagcag atgacttggt
    39241 ttcgggtcag tcaaccttta tggtggagat gatggaggcc aataatgcca tttcgcatgc
    39301 gaccaagaac tctctcattc tctttgatga attgggacgt ggaactgcaa cttatgacgg
    39361 gatggctctt gctcagtcca tcatcgaata tatccatgag cacatcggag ctaagaccct
    39421 ctttgcgacc cactaccatg agttgactag tctggagtct agtttacaac acttggtcaa
    39481 tgtccacgtg gcaactttgg agcaggatgg gcaggtcacc ttccttcaca agattgaacc
    39541 gggaccagct gataaatcct acggtatcca tgttgccaag attgctggct tgccagcaga
    39601 ccttttagca agggcggata agattttgac tcagctagag aatcaaggaa cagagagtcc
    39661 tcctcccatg agacaaacta gtgctgtcac tgaacagatt tcactctttg atagggcaga
    39721 agagcatcct atcctagcag aattagctaa actggatgtg tataatatga cacctatgca
    39781 ggttatgaat gtcttagtag agttaaaaca gaaactataa aaccaagact cactagttaa
    39841 tctagctata tcaaggagac ttctttgaca attctccact tttttgctag aataacatca
    39901 cacaaacaga atgaaaagga gctgacgcat tgtcgctccc ttttgtctat tttttaagga
    39961 gaaagtatgc tgattcagaa aataaaaacc tacaagtggc aggccttggc ttcgctcctg
    40021 atgacaggct tgatggttgc tagttcactt ctgcaaccgc gttatctgca ggaagtatta
    40081 gacgccctcc ttactgggaa atatgaagct atttatagta tcggggcttg gttgattggt
    40141 gtggccgtag tcggtctagt tgctggtgga ctcaatgttg tcctcgcagc ctatattgcc
    40201 caaggagttt catccgacct tcgggaggat gccttccgta aaattcaaac cttttcttat
    40261 gctgatattg aacaatttaa tgcgggaaat ctagtcgttc gaatgacaaa tgatatcaac
    40321 cagattcaga acgttgtcat gatgaccttc caaattcttt tcagacttcc cctcttgttc
    40381 atcggttcgt ttatcctagc ggttcaaacc ttaccttctc tgtggtgggt gattgttctc
    40441 atggtagtct tgatttttgg tttgactgct gtcatgatgg gaatgatggg gcctcgtttt
    40501 gccaagtttc aaacccttct tgagcgcatc aatgccattg ccaaggaaaa tttacgtggc
    40561 gttcgtgtgg tcaagtcctt tgtccaagaa aaagagcaat ttgctaagtt tacagaggtc
    40621 tcagacgagc tttttggtca aaacctttac attggttatg ccttttcagt agtggaaccc
    40681 tttatgatgt tggttggtta cggggcggtc ttcctctcta tttggctggt cgcgggaatg
    40741 gttcagtcgg atccgtctgt tgttggttcc atcgcttctt ttgttaatta cctaagccag
    40801 attatcttta ccattgttat ggttggattt ttgggaaatt ctgtcagccg tgccatgatt
    40861 tccatgcgtc gtattcgaga aattcttgac gcagagccag ctatgacctt caaggatatc
    40921 ccagatgaag agttggttgg aagccttagc tttgaaaatg tgacctttac ctatccaatg
    40981 gacaaggaac cgatgctgaa agatgtgagc tttactattg aacctggtca aatggttggt
    41041 gtagttggag cgactggtgc aggaaagtca accttggctc aattgattcc acgtctcttt
    41101 gatccacaga acggggccat taaaatcggt ggcaaggata ttcgagaagt gagtgaagga
    41161 accctgcgta aaacagtttc catcgttctc caacgtgcca ttctttttag tggaacgatt
    41221 gcagataact tgagacaggg gaagggaaat gctactctat ttgaaatgga gcgcgcagcc
    41281 aatattgccc aggctagtga attcattcat cgtatggaga aaacctttga aagtccagtt
    41341 gaagaacggg gaaccaattt ctctggtgga caaaaacaaa ggatgtcgat tgcgcgtggg
    41401 attgtcagca atccacgtat tctgattttt gacgattcga cctcagcctt ggatgccaaa
    41461 tcagagcgct tggtgcaaga agctttgaat aaggacttga aggggacgac aaccattatt
    41521 attgctcaaa aaattagctc ggttgtccat gcagacaaga tcttggttct aaatcaagga
    41581 cgattgattg gtcaaggcac gcatgcagac ttggttgcca acaatgccgt ttaccgtgaa
    41641 atctatgaaa cacagaaatg aaagacaaac tataagaaaa gtcaatagtt ttatctaaat
    41701 tatttcttat ttcaatttga tgatttggcg atgattttag agcacggcaa aaagcccttg
    41761 aaaaagtcca ttttttcaaa ggtaatcctg tgttgatttc agaaattaca tcactttttg
    41821 ttcgtcaaat ggcagctctt ttttaggata taaaacaggg ttcggataag tttttttgca
    41881 aggtggatga tggctacatt gtaatgtttt ccttattcta acttagtctt aagataggcc
    41941 ttaaaagcag gtgaaaagcg agggcatgct ttggcagctt gtatgagtgc ctaccgcaga
    42001 tgaggggaac cccgtttgat cattcttcca gctaaatcaa tctgatctga ctgataaata
    42061 gaagaatcca gtccagcgaa agcttgtaat tgagcaagat tatcaaaggc atgaatattt
    42121 cgaatctcgg ctaaaatgac cgcccctaaa cgattcccaa tcccagtaac cgtcgtgatg
    42181 atcgagttga actcagccat caagtcattg acacatgttt ccgccttgtc aatgagcctc
    42241 ttgtaatgtt tgatgttttc attacacgag ataaaacgtt tatgcgttat caaactcatg
    42301 accaattgaa acaaaaagct gtggttagat cctttcggaa attgtcaagc gattggagga
    42361 aatgaactaa tccacagcgg cttattccaa gtataccact tgggctttgg cagtagctaa
    42421 ctgcgctaaa tataatataa ggaggagtaa aatgaagaca gttcaatttt tttggcatta
    42481 ttttaaggtt tacaagttct catttgtagt tgtcatcctg atgattgttc tggcgacttt
    42541 tgcccaagcc ctctttccag tcttttctgg acaagcggtg acgcagctag ccaatttagt
    42601 tcaagcttat caaaatggca atccagaact tgtatggcaa agcctatcag gaatcatggt
    42661 caatcttggc ctgctggttt tggttctatt tatctctagt gtaatataca tgtgtctcat
    42721 gacgcgcgtg attgcagaat cgaccaacga gatgcgcaaa ggcctctttg gtaagcttgc
    42781 tcagttgacg gtttctttct ttgaccgtcg acaagatggc gatatcctgt ctcattttac
    42841 cagtgatttg gataatatcc tccaagcctt taacgaaagc ttgattcagg tcatgagcaa
    42901 tattgtttta tacattggtc tgattcttgt catgttttcg agaaatgtga cgctggctct
    42961 catcaccatt gccagcaccc cattggcttt ccttatgctg attttcatcg tgaaaatggc
    43021 acgcaaatac accaacctcc agcagaaaga ggtagggaag ctcaacgcct atatggatga
    43081 gagcatctca ggccaaaaag ccgtgattgt gcaaggaatt caagaggata tgatggcagg
    43141 atttcttgaa caaaatgagc gcgtgcgcaa ggcaaccttt aaaggaagaa tgttctcagg
    43201 aattcttttc cctgtcatga atgggatgag cctgattaat acagccatcg tcatctttgc
    43261 tggttcggct gtacttttga atgataagtc tattgaaaca agtacagccc taggtttgat
    43321 tgttatgttt gcacaatttt cacagcagta ctaccagcct attatccaag ttgcagcgag
    43381 ttggggaagc cttcagttgg cctttactgg agctgaacga attcaggaaa tgtttgatgc
    43441 agaggaggaa atccgacctg aaaaggctcc aaccttcact aagttgcaag aaagtgttga
    43501 aatcagtcat atcgattttt catacttgcc tgataaacct attttgaaag atgtcagcat
    43561 ttctgcccct aaaggccaga tgacagcagt tgttgggccg acaggttcag gaaaaacgac
    43621 tattatgaac ctcatcaatc gcttttatga tgttgatgct ggtggtattt attttgatgg
    43681 taaagacatt cgtggctatg atttagatag tcttagaagc aaggtgggaa ttgtattgca
    43741 agattcggtc ttgtttagcg gaacgattcg agacaatatc cgatttggtg tgccagatgc
    43801 tagtcaggaa atggttgagg tagcagcaaa agcaacccac attcacgact atatcgaaag
    43861 tttgcctgat aagtacgata ctcttattga tgatgaccag agcatctttt caacagggca
    43921 gaagcaattg atttcaatcg ctcgaaccct gatgacagat ccagaagttc tcattctcga
    43981 tgaagcaact tcaaacgtag atacggtgac agaaagcaag attcagcatg ccatggaggt
    44041 ggttgtagca ggtagaacta gtttcgtcat tgcccaccgc ttgaaaacca ttctcaatgc
    44101 agatcagatt attgtcctta aagatggaga agtcattgaa cgtggtaacc accatgaact
    44161 tttgaagcta ggtggctttt attcagaact ctatcacaat caatttgttt tcgaataaga
    44221 aagaagttgt cctatgtggg cagctttttc ttgtccataa aaaatgttta tcacagcctt
    44281 aaaaaaaaca tattagacga aagtcatttt gagtgatatg ataggactat cgttagcatt
    44341 cgaaaggaga ggcatcatgg ctagaacggt tgtaggagtt gctgcaaatc tatgtcccgt
    44401 agacgcagaa ggcaaaatca ttcattcatc tgtatcttgt agattcgcag agatcattcg
    44461 tcaagtcggt ggtctccctt tagtcattcc tgttggtgat gagtcagttg tgcgtgatta
    44521 tgtggaaatg attgacaaac tcattttgac aggaggccaa aatgttcatc ctcagtttta
    44581 tggagagaaa aagactgtcg agagcgatga ttacaatctg gtccgtgacg aatttgaatt
    44641 ggcactcttg aaggaagcgc ttcgtcagaa taaaccaatt atggcaatct gtcgcggtgt
    44701 ccaacttgtc aatgttgcct ttggtggaac cctcaatcaa gaaatcgaag gtcactggca
    44761 aggactacct ttcgggacat ctcactctat tgagacagta gaaggaagcg tggtggctaa
    44821 gctatttggg aaagaaagtc aggtcaactc agtccatcgt caaagcatta aagatttggc
    44881 acctaatttc cgtgtaactg ctattgattc aagagaccaa actattgaag cgattgagtc
    44941 tatcgacgag caccgcatta tcggtttaca gtggcatcca gagtttctgg ttaatgaaga
    45001 agatggcaat ttagaattat ttgagtattt attgaatgaa ctgtaacgat tggaacatct
    45061 ggtcgttctt tcttttattt tttcaaaatt tttagaatgt ggcattttac gcaaacgttt
    45121 gaattctgat aaaaattgga gaaattcgac aaaaaaactt gaaaaaaacg aaggtaagcg
    45181 ttatgataga aaagaagaaa tattggagga agaacatgtc acatattaaa tttgattatt
    45241 caaaagtttt agacaaattt gttgcaccac atgaagtgga atacatgcaa tcacaagtaa
    45301 cagcagcaga tgaattgatc cgtaaaggaa ctggtgctgg tagcgacttc ttgggatggt
    45361 tggaccttcc tgaaaaatac gatcgcgaag aatttgaccg catcttgaaa gctgctgagc
    45421 aaatcaagtc agacagcgat gttttggttg tgatcggtat tggtggatct taccttggtg
    45481 caaaagcagc aatcgacttc ttgaatcacc attttgctaa cttgcaaaca aaagaagaac
    45541 gcaaagctcc acaaatcctt tacgcaggaa actcaatctc atctacttac cttgctgact
    45601 tggtagagta tgttgcagac aaagacttct cagtaaacgt aatttctaaa tcaggtacaa
    45661 caactgaacc agcgattgct ttccgtgtct ttaaagaact cttggttaag aaatacggtc
    45721 aagaagaagc taacaaacgt atctatgcaa caactgaccg ccaaaagggt gctgttaagg
    45781 ttgaagcaga cgctaacggt tggggaacat ttgttgttcc agatgatatc ggtggacgct
    45841 tctcagtatt gacagccgtt ggtttgcttc caatcgcagc atcaggagct gacatcaaag
    45901 ctcttatgga aggtgcgaat gcagctcgca aagactacac ttcagacaaa atctctgaaa
    45961 acgaagctta ccaatacgca gccgttcgta acatccttta tcgtaaaggc tatgcaactg
    46021 agatcttggt aaactatgag ccatcacttc aatacttctc agaatggtgg aaacaattgg
    46081 ctggtgaatc agaaggaaaa gaccaaaaag gtatctaccc aacttcagcc aacttctcaa
    46141 ctgacttgca ctcacttggt caatttatcc aagaaggaac tcgtatcatg tttgaaacag
    46201 ttgtccgtgt tgacaaacct cgtaaaaacg tgcttattcc tactttggaa gaagaccttg
    46261 acggacttgg ttaccttcaa ggaaaagacg ttgactttgt aaacaaaaaa gcaactgacg
    46321 gtgttcttct tgcccacaca gatggtgatg taccaaacat gtatgtgact cttccagagc
    46381 aagacgcttt cactcttggt tacactatat acttcttcga attggcaatt gccctttcag
    46441 gttacttgaa tgctatcaac ccatttgacc aaccaggtgt tgaagcttat aaacgtaaca
    46501 tgtttgccct tcttggaaaa ccaggatttg aagaattgag caaagaactt aacgcacgtc
    46561 tataatagaa gaaaagagtg gtttgcccac tctttttact ctctttatcc atagaaattg
    46621 gactcagcta agacttgtga tataatatag aaagcaaaaa ggcagacgcc tagataatag
    46681 gagaaactat gtcaaaagat atccgcgtac gttacgcacc aagtccaaca ggactactac
    46741 acatcggaaa tgctcgtaca gcattgttta actacttgta tgcgcgccat catggtggaa
    46801 catttctcat ccgtatcgaa gatactgacc gtaaacgcca tgtcgaggat ggtgaacgtt
    46861 cacaacttga aaaccttcgc tggttaggca tggattggga tgaaagtcca gaatcacatg
    46921 agaattatcg ccagtctgag cgtttggact tgtatcaaaa atacattgac caactattag
    46981 ctgaaggaaa agcctataaa tcttacgtta cagaagaaga gttggcagct gaacgcgaac
    47041 gccaagaagt agctggcgaa acaccacgct acatcaatga ataccttggt atgagtgaag
    47101 aagaaaaagc agcttacatc gcagaacgtg aagcagcagg gatcatccca actgttcgtt
    47161 tggctgtcaa tgagtcaggt atctacaagt ggcatgatat ggtcaaaggc gatatcgaat
    47221 ttgaaggtgg caatatcggt ggtgactgga ttatccaaaa gaaagacggt tacccaactt
    47281 acaactttgc cgttgccatc gatgaccatg atatgcaaat ctcccatgtt atccgtggag
    47341 acgaccatat tgctaacaca ccaaaacagc tcatggttta tgaagcactt ggttgggaag
    47401 ctccagagtt tggtcacatg accttgatta tcaactctga gactggtaag aagttatcta
    47461 aacgtgatac taatacactt caatttatcg aagattaccg aaagaaaggt taccttccag
    47521 aagcagtctt taactttatt gctcttcttg gttggaaccc aggtggtgaa gatgagattt
    47581 tctctcgtga agaactcatt aaactttttg atgaaaaccg cctcagcaag tcaccagcag
    47641 cctttgatca gaaaaaacta gactggatga gcaatgatta tatcaagaat gcagaccttg
    47701 aaaccatctt tgaaatggca aaaccattct tagaggaagc aggccgtttg actgacaagg
    47761 ctgaaaaatt agttgagctc tataaaccac aaataaaatc agtagatgag attatcccat
    47821 tgacagatct tttcttctca gatttcccag aattgacaga agcagagcgc gaagtcatga
    47881 cgggtgaaac agttccaaca gttcttgaag cattcaaagc aaaacttgaa gagatgacag
    47941 ataatgaatt tgtgacagaa aatatcttcc cacaaattaa agcagtccaa aaagaaacag
    48001 gtattaaagg gaaaaatctt ttcatgccta ttcgtatcgc agtttcaggc gaaatgcatg
    48061 ggccagaatt accagataca attttcttgc ttggacgtga aaaatcaatt cagcatatcg
    48121 aaaacatgct aaaagaaatc tctaaataaa gaggatacaa taatggacat ctgggaaaag
    48181 atgtacgaag aagcacagaa actatacaat ccacatgaag tatcagactt tgtttatgcc
    48241 aatcatgttg tagctgcagt agaagcagaa gatggacaaa tatttacagg attctgtatg
    48301 gagggaacct gtggtgtttt ccatctctgc gcagaacggg cggccctctt caatatgtac
    48361 caattttcag gacaaactaa ggttaagaaa gtattagcct ttcgagataa accaccttat
    48421 ggtggaagtt cagccatgcc ttgcggtgct tgtagagaat tccttttaga gcttaatgct
    48481 gaaaataaag atgcagaatt catgatggac tataatataa gaaaaacagt taaagtcgca
    48541 gaactaatcc cttattggtg gggagaagaa cgtgcttcta agtttaatga gcgatagaag
    48601 agtcagtata attctggctc tttttgccat aagttgaaaa aata
//
LOCUS       DBEJAU010000007        47082 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC323 isolate 683620
            SAMN38261939-rid24807223.denovo.007, whole genome shotgun sequence.
ACCESSION   DBEJAU010000007 DBEJAU010000000
VERSION     DBEJAU010000007.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261939
            Sequence Read Archive: SRR26833919
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 47082)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 47082)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576303.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576303.1
            Genome Coverage       :: 154x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/19/2025 01:05:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,121
            CDSs (total)                      :: 2,078
            Genes (coding)                    :: 1,943
            CDSs (with protein)               :: 1,943
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 36
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 72 of 135
            Pseudo Genes (incomplete)         :: 63 of 135
            Pseudo Genes (internal stop)      :: 51 of 135
            Pseudo Genes (multiple problems)  :: 46 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..47082
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261939-rid24807223.denovo.007"
                     /strain="GPSC323"
                     /isolate="683620"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            19..399
                     /locus_tag="ACL29Z_000476"
     CDS             19..399
                     /locus_tag="ACL29Z_000476"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000769852.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0068832.1"
                     /translation="MKLKTLALISGIVGLVGGILLLIGPFVLLGTTVNTAATTLNGGA
                     TAGAFSGVALLLNALKIENLVLGIIAIVYYKGDKRVGAAPSVLMIVSGGVSLIPFLGW
                     VGGILAIIGGSLFLATLKKFKSEE"
     gene            934..1626
                     /locus_tag="ACL29Z_000477"
     CDS             934..1626
                     /locus_tag="ACL29Z_000477"
                     /EC_number="5.4.2.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006703946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglycerate mutase"
                     /protein_id="HGR0068833.1"
                     /translation="MVKLVFARHGESEWNKANLFTGWADVDLSEKGTQQAIDAGKLIK
                     EAGIEFDQAYTSVLKRAIKTTNLALEASDQLWVPVEKSWRLNERHYGGLTGKNKAEAA
                     EQFGDEQVHIWRRSYDVLPPNMDRDDEHSAHTDRRYASLDDSVIPDAENLKVTLERAL
                     PFWEDKIAPALKDGKNVFVGAHGNSIRALVKHIKGLSDDEIMDVEIPNFPPLVFEFDE
                     KLNVVSEYYLGK"
     gene            1679..4090
                     /locus_tag="ACL29Z_000478"
     CDS             1679..4090
                     /locus_tag="ACL29Z_000478"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000620712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 95 protein"
                     /protein_id="HGR0068834.1"
                     /translation="MIRNKKQDYVLAYKQPASTTYMGWEEEALPIGNGSLGAKVFGLI
                     GSERIQFNEKSLWSGGPLPDSSDYQGGNLQDQYVFLAEIRQALEKRDYNLAKELAEQH
                     LIGPKTSQYGTYLSFGDIHIEFSQQGTTLSQVTDYQRQLNISKALATTSYVYKGTRFE
                     REAFASFPDDLLVQCFTKEGLETLDFTIELSLTCDLASDGKYEQEKSDYKECKLDITD
                     SHILMKGRVKDNDLRFASYLAWETDGDIRVWSDRVQISGASYANLFLAAKTDFAQNPA
                     SNYRKKLDLEQQVIDLVDTAKEKGYTQLKSRHIEDYQALFQRVQLDLEADVDASTTDD
                     LLKNYKPQEGQALEELFFQYGRYLLISSSRDCPDALPANLQGVWNAVDNPPWNSDYHL
                     NVNLQMNYWPAYVTNLLETVFPVINYVDDLRVYGRLAAVKYAGIVSQKGEENGWLVHT
                     QATPFGWTAPGWDYYWGWSPAANAWMMQTVYEAYSFYRDQDYLREKIYPMLRETVRFW
                     NAFLHKDQQAQRWVSSPSYSPEHGPISIGNTYDQSLIWQLFHDFIQAAQELGLDENLL
                     TEVKEKSDLLNPLQITQSGRIREWYEEEEQYFQNEKVEAQHRHASHLVGLYPGNLFSY
                     KGQEYIEAARASLNDRGDGGTGWSKANKINLWARLGDGNRAHKLLAEQLKISTLPNLW
                     CSHPPFQIDGNFGATSGMAEMLLQSHAAYLVPLAALPDAWSTGSVSGLMARGHFEVSM
                     SWEDKKLLQLTILSRSGGDLRVSYPDIEKSVIKMNQEKIKAKCMGKDCISVATAEGDL
                     VQFYF"
     gene            4340..5041
                     /locus_tag="ACL29Z_000479"
     CDS             4340..5041
                     /locus_tag="ACL29Z_000479"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGR0068835.1"
                     /translation="MAYIEMKHCYKRYQVGDTEIVANRDVNFEIEKGELVIILGASGA
                     GKSTVLNLLGGMDTNDEGEIWIDGVNIADYSSHQRTNYRRNDVGFVFQFYNLVSNLTA
                     KENVELASEIVTDALNPAQVLTDVGLAHRLNNFPAQLSGGEQQRVSIARAVAKNPKIL
                     LCDEPTGALDYQTGKQVLKILQDMSRQKGATVIIVTHNGALAPIADRVIHMHDASVKD
                     VVLNQHPQDIDSLEY"
     gene            5043..7751
                     /locus_tag="ACL29Z_000480"
     CDS             5043..7751
                     /locus_tag="ACL29Z_000480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000595876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FtsX-like permease family protein"
                     /protein_id="HGR0068836.1"
                     /translation="MIKRKTYWKDLIQSFTGSKGRFLSILILMMLGSLALVGLKVTSP
                     NMETTANAYLTTAQTLDLAVMSNYGLDQADQEELKQTEGAEVEFGYLTDVTMDNGQDA
                     IRLYSKPERISTFQLRKGRLPQSDKEIALATHLQGQYSVGQEISFKEKEEGHSSLKDH
                     TYTITGFVDSAEILSQRDMGYAGSGSGTLTAYGVILPSQFDQKVYNIARLKYQDLAGL
                     NAFSSAYEEKSKQHQEELEQILSDNGKVRLQLLKKEGQESLDKGQETLDKAQTNLQEG
                     KRRLAAAQARIQAQESQLALFPQVQREQASAQLTQAKQELGKEEAKLKQAEQNLAQEK
                     EKLEKHQQVLDDLAEPRYQVYNRQTMPGGQGYLMYSNASSSIRAVGNIFPVVLYAVAA
                     MVTFTTMTRFVDEERTHAGIFKALGYRSKDIIAKFLLYGLVAGTVGTALGSILGHYLL
                     ANVISSVITKGMVVGETQIQFYWTYSLLALVLSLLASVLPAYLVAWRELHDEAAQLLL
                     PKPPVKGAKILLERIGFIWRRLSFTHKVTARNIFRYKQRMLMTIFGVAGSVALLFAGL
                     GIQSSVAGVPSKQFQQIQQYQMLVSENPSATNQDKVELAEVLKGQEILAYQKIYSKAL
                     DKDFKGKAGLQNITLMMIEKEDLTPFIHLQHHQQELTLKDGIVITAKLAQLAGVKVGQ
                     TLEIEGKELKVAAITENYVGHFIYMSQASYEQLYGQLPQANTYLVSLRDTSATSIESQ
                     AGLLMNQSAVSSVVQNASAIRLFDSIASSLNQTMTILVIVSVLLAIVILYNLTNINVA
                     ERIRELSTIKVLGFHNNEVTLYIYRETIVLSLVGIVLGLVAGFYLHQFLIQMISPATI
                     LFYPQVGWEVYVIPVATVSIILTLLGFFVNYYLRKVDMLEALKSVE"
     gene            complement(7847..8338)
                     /gene="tpx"
                     /locus_tag="ACL29Z_000481"
     CDS             complement(7847..8338)
                     /gene="tpx"
                     /locus_tag="ACL29Z_000481"
                     /EC_number="1.11.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004245092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008379 - thioredoxin peroxidase activity
                     [Evidence IEA];
                     GO_function: GO:0016684 - oxidoreductase activity, acting
                     on peroxide as acceptor [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="thiol peroxidase"
                     /protein_id="HGR0068837.1"
                     /translation="MVTFLGNPVSFTGKQLQVGDKALDFSLTTTDLSKKSLADFDGKK
                     KVLSVVPSIDTGICSTQTRRFNEELAGLDNTVVLTVSMDLPFAQKRWCGAEGLDNAIM
                     LSDYFDHSFGRDYALLINEWHLLARAVFVLDTDNTIRYVEYVDNINSEPNFEAAIAAA
                     KAL"
     gene            complement(8461..9390)
                     /gene="psaA"
                     /locus_tag="ACL29Z_000482"
     CDS             complement(8461..9390)
                     /gene="psaA"
                     /locus_tag="ACL29Z_000482"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000733059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter substrate-binding
                     lipoprotein/adhesin PsaA"
                     /protein_id="HGR0068838.1"
                     /translation="MKKLGTLLVLFLSAIILVACASGKKDTTSGQKLKVVATNSIIAD
                     ITKNIAGDKIDLHSIVPIGQDPHEYEPLPEDVKKTSEADLIFYNGINLETGGNAWFTK
                     LVENAKKTENKDYFAVSDGVDVIYLEGQNEKGKEDPHAWLNLENGIIFAKNIAKQLSA
                     KDPNNKEFYEKNLKEYTDKLDKLDKESKDKFNKIPAEKKLIVTSEGAFKYFSKAYGVP
                     SAYIWEINTEEEGTPEQIKTLVEKLRQTKVPSLFVESSVDDRPMKTVSQDTNIPIYAQ
                     IFTDSIAEQGKEGDSYYSMMKYNLDKIAEGLAK"
     gene            complement(9422..10270)
                     /locus_tag="ACL29Z_000483"
     CDS             complement(9422..10270)
                     /locus_tag="ACL29Z_000483"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000559784.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter permease subunit"
                     /protein_id="HGR0068839.1"
                     /translation="MIAEFIDGLQKFHFLQNALITAIVVGIVAGAVGCFIILRGMSLM
                     GDAISHAVLPGVALSFILGLDFFIGAIVFGLLAAIIITYIKGNSIIKSDTAIGITFSS
                     FLALGIILIGVAKSSTDLFHILFGNILAVQDTDMFITMGVGAAILLLIWIFFKQLLIT
                     SFDELLAKAMGMPVNFYHYLLMVLLTLVSVTAMQSVGTILIVAMLITPAATAYLYANS
                     LKSMIFLSSTFGATASVLGLFIGYSFNVAAGSSIVLTAASFFLISFFIAPKQRYLKLK
                     NKHLLK"
     gene            complement(10267..10989)
                     /locus_tag="ACL29Z_000484"
     CDS             complement(10267..10989)
                     /locus_tag="ACL29Z_000484"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000619140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter ATP-binding protein"
                     /protein_id="HGR0068840.1"
                     /translation="MIRIENLSVSYKETLALKDISLVLHGPTITGIIGPNGAGKSTLL
                     KGMLGIIPHQGQAFLDDKEVKKSLHRIAYVEQKINIDYNFPIKVKECVSLGLFPSIPL
                     FRSLKAKHWKKVQEALEIVGLADYAERQISQLSGGQFQRVLIARCLVQEADYILLDEP
                     FAGIDSVSEEIIMNTLRDLKKAGKTVLIVHHDLSKIPHYFDQVLLVNREVIAFGPTKE
                     TFTETNLKEAYGNQLFFNGGDL"
     gene            11280..13172
                     /gene="pepO"
                     /locus_tag="ACL29Z_000485"
     CDS             11280..13172
                     /gene="pepO"
                     /locus_tag="ACL29Z_000485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000199272.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endopeptidase PepO"
                     /protein_id="HGR0068841.1"
                     /translation="MTRYQDDFYDAINGEWQQTAEIPADKSQTGGFVDLDQEIEDLML
                     ATTDKWLAGEEVPEDAILENFVKYHRLVRDFDKREADGITPVLPLLKEFQELETFADF
                     TAKLAEFELAGKPNFLPFGVSPDFMDARINVLWASAPSTILPDTTYYAEEHPQREELL
                     TLWKESSANLLKAYDFSDEEIEDLLEKRLELDRRVAAVVLSNEESSEYAKLYHPYSYE
                     DFKKFAPALPLDDFFKAVIGQLPDKVIVDEERFWQAAEQFYSEEAWSLLKATLILSVV
                     NLSTSYLTEDIRVLSGAYSRALSGVPEAKDKVKAAYHLAQEPFKQALGLWYAREKFSP
                     EAKADVEKKVATMIDVYKERLLKNDWLTPETCKQAIVKLNVIKPYIGYPEELPARYKD
                     KVVNETASLFENALAFARVEIKHSWSKWNQPVDYKEWGMPAHMVNAYYNPQKNLIVFP
                     AAILQAPFYDLHQSSSANYGGIGAVIAHEISHAFDTNGASFDENGSLKDWWTESDYAA
                     FKEKTQKVIDQFDGQDSYGATINGKLTVSENVADLGGIAAALEAAKREADFSAEEFFY
                     NFGRIWRMKGRPEFMKLLASVDVHAPAKLRVNVQVPNFDDFFTTYDVKEGDGMWRSPE
                     ERVIIW"
     gene            complement(13295..13924)
                     /locus_tag="ACL29Z_000486"
     CDS             complement(13295..13924)
                     /locus_tag="ACL29Z_000486"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000690864.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HGR0068842.1"
                     /translation="MKIHKTVNPVAYENTYYLEGEKHLIVVDPGSHWEAIRQTIEKIN
                     KPICAILLTHAHYDHIMSLDLVRETFGNPPVYIAESEASWLYTPVDNLSGLPRHDDMA
                     DVVTKPAEHTFVFHEEYQLEEFRFKVLPTPGHSIGGVSLVFPDAHLVLTGDALFRETI
                     GRTDLPTGSMEQLLHSIQTQLFTLPNYDVYPGHGPATTIAHEKAFNPFF"
     gene            14920..17142
                     /locus_tag="ACL29Z_000487"
     CDS             14920..17142
                     /locus_tag="ACL29Z_000487"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019316080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0015968 - stringent response [Evidence
                     IEA];
                     GO_process: GO:0015969 - guanosine tetraphosphate
                     metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RelA/SpoT family protein"
                     /protein_id="HGR0068843.1"
                     /translation="MPKEVNLTGEEVVALTKEYLTEEDVHFVHKALVYAVECHSGQYR
                     KSGEPYIIHPIQVAGILAKLKLDAVTVACGFLHDVVEDTDATLDDLEREFGPDVRVIV
                     DGVTKLGKVEYKSIEEQLAENHRKMLMAMSEDIRVILVKLSDRLHNMRTLKHLRKDKQ
                     ERISKETMEIYAPLAHRLGISSVKWELEDLSFRYLNPTEFYKITHMMKEKRREREALV
                     DEVVTKLEEYTTERHLKGKIYGRPKHIYSIFRKMQDKRKRFEEIYDLIAIRCILDTQS
                     DVYAMLGYVHEFWKPMPGRFKDYIANRKANGYQSIHTTVYGPKGPIEFQIRTKEMHEV
                     AEYGVAAHWAYKKGIKGQVNSKESAIGMNWIKEMMELQDQADDAKEFVDSVKENYLAE
                     EIYVFTPDGAVRSLPKDSGPIDFAYEIHTKVGEKATGAKVNGRMVPLTTKLKTGDQVE
                     IIANPNSFGPSRDWLNMVKTSKARNKIRQFFKNQDKELSVNKGREMLMAQFQENGYVA
                     NKFMDKRHMDQVLQKTSYKTEDSLFAAIGFGEIGAITVFNRLTEKERREEERAKAKAE
                     AEELVKGGEVKVENKETLKVKHEGGVVIEGASGLLVRIAKCCNPVPGDDIVGYITKGR
                     GVAIHRVDCMNLRAQENYEQRLLDVEWEDQYSSSNKEYMAHIDIYGLNRTGLLNDVLQ
                     VLSNTTKNISTVNAQPTKDMKFANIHVSFGIANLSTLTTVVDKIKSVPEVYSVKRTNG
                     "
     gene            17172..17615
                     /gene="dtd"
                     /locus_tag="ACL29Z_000488"
     CDS             17172..17615
                     /gene="dtd"
                     /locus_tag="ACL29Z_000488"
                     /EC_number="3.1.1.96"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004045 - aminoacyl-tRNA hydrolase
                     activity [Evidence IEA];
                     GO_process: GO:0008152 - metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="D-aminoacyl-tRNA deacylase"
                     /protein_id="HGR0068844.1"
                     /translation="MKIIIQRVKKAQVSIEGQIQGKINQGLLLLVGVGPEDQEEDLDY
                     AVRKLVNMRIFSDAEGKMNLSVKDIEGEILSISQFTLFADTKKGNRPAFTGAAKPDMA
                     SDFYDAFNQKLAQEVPVQTGIFGADMQVELVNNGPVTIILDTKKR"
     gene            18406..18789
                     /locus_tag="ACL29Z_000489"
     CDS             18406..18789
                     /locus_tag="ACL29Z_000489"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000514168.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0068845.1"
                     /translation="MGKENVRMRLASESRQILDKLKDDVYNKLGYEVSYSSIVSQAVR
                     EYVPKKERIDWIKLKETAIPFSSLKQSNNWEYQTSLMLEKDVLILLSELQNFFLDVFQ
                     AKRIHRAFCIRLCLRAQFLLSNNDS"
     gene            19197..19496
                     /locus_tag="ACL29Z_000490"
     CDS             19197..19496
                     /locus_tag="ACL29Z_000490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001081475.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0068846.1"
                     /translation="MNRNVLNFLRTESAERVSLYIDKANRLEGDVTLLAPSSQDLEDI
                     KNAMFSNPNLELKVARLDVMKKIAYASTRNHYLTGATIFGDISKGTYNCDPKSYV"
     gene            complement(19591..20028)
                     /locus_tag="ACL29Z_000491"
     CDS             complement(19591..20028)
                     /locus_tag="ACL29Z_000491"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000737922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0068847.1"
                     /translation="MKKLYRIHFIAIAVIDLLLFAFFITRLETSFEWLLLSGLIFFLA
                     QGLLLFLLVVRLKHQFAEIYPQINKKIRFYYLGVLTIDFLFFVLLAFISSQRFSSLMP
                     IITACHSTFYYMTADYLRENYPDFYDKHISNTYTILSISSFLV"
     gene            complement(20130..20679)
                     /locus_tag="ACL29Z_000492"
                     /pseudo
     CDS             complement(20130..20679)
                     /locus_tag="ACL29Z_000492"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820364.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0034257 - nicotinamide riboside
                     transmembrane transporter activity [Evidence IEA];
                     GO_process: GO:0034258 - nicotinamide riboside transport
                     [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinamide mononucleotide transporter"
     gene            complement(21003..21653)
                     /locus_tag="ACL29Z_000493"
     CDS             complement(21003..21653)
                     /locus_tag="ACL29Z_000493"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000188500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-dependent transcriptional regulator"
                     /protein_id="HGR0068848.1"
                     /translation="MTPNKEDYLKCIYEIGIDLHKITNKEIAARMQVSPPAVTEMIKR
                     MKSENLILKDKECGYLLTDLGLKLVSELYRKHRLIEVFLVHHLDYTSDQIHEEAEVLE
                     HTVSDLFVERLDKLLGFPKTCPHGGTIPAKGELLVEINNLPLADIKEAGAYRLTRMHD
                     SFDILHYLDKHSLHIGDQLQVKQFDGFSNTFTILSNDEDLQVNMDIAKQLYVEKIN"
     gene            21765..22607
                     /locus_tag="ACL29Z_000494"
     CDS             21765..22607
                     /locus_tag="ACL29Z_000494"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase family protein"
                     /protein_id="HGR0068849.1"
                     /translation="MTKIALLSDIHGNTTALEAVLADARQLGVDEYWLLGDILMPGTG
                     RRRILDLLDQLPITARVLGNWEDSLWHGVRKELDSTRPSQRYLLRQCQYVLEEISLEE
                     IEVLHNQPLQIHRQFGDLTVGISHHLPDKNWGRELIHTGKQEEFDRLVTHPPCDIAVY
                     GHIHQQLLRYGTGGQLIVNPGSIGQPFFLDAQLRKDLRAQYMILEFDDKGLVDMDFRR
                     VDYDVAAELQLAKDLRLPYFEVYYESLVNGIHHTHHQEFLRELAQKEGCDRELDDWLK
                     SGND"
     gene            22683..23120
                     /locus_tag="ACL29Z_000495"
     CDS             22683..23120
                     /locus_tag="ACL29Z_000495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004263219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Rrf2 family transcriptional regulator"
                     /protein_id="HGR0068850.1"
                     /translation="MQIPSRFTIATHMLIIIALEGKKSKVTSDFLAASVGVNPVIIRK
                     ILSQLKKAELISVARGTGGTDIVKDLKDISLLDVYQAVECLGKTGQLFSFHDNPNPNC
                     PVGAHIHDVLDQKLERIQLTMEAELGQTSLEKVVADAESQMKD"
     gene            23188..23490
                     /locus_tag="ACL29Z_000496"
     CDS             23188..23490
                     /locus_tag="ACL29Z_000496"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000281600.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0068851.1"
                     /translation="MYLVIGIVLAFIVSFWKDNRSLWNPVLFLLSLISSYFYLSYLFY
                     KNGYENVQLAFYVFAFVLLPFLLFLSGIFLIYNGVILLKREGRSKPNYLSMLFDFY"
     gene            complement(23581..24654)
                     /locus_tag="ACL29Z_000497"
     CDS             complement(23581..24654)
                     /locus_tag="ACL29Z_000497"
                     /EC_number="3.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001273827.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2974 domain-containing protein"
                     /protein_id="HGR0068852.1"
                     /translation="MANIFDYLKDVAYDSYYDLPLNELDILTLIEITYLSFDNLVSTL
                     PQRLLDLAPQVPREPTMLTSKNRLQLLDELAQHKRFKNCKLSHFINDIDPELQKQFAA
                     MTYRVSLDTYLIVFRGTDDSIIGWKEDFHLTYMKEIPAQKHALRYLKNFFAHHPKQKV
                     ILAGHSKGGNLAIYAASQIEQSLQNQITAVYTFDAPGLHQELTQTAGYQRIMDRSKIF
                     IPQGSIIGMMLEIPAHQIIVQSTALGGIAQHDTFSWQIEDKHFVQLDKTNSDSQQVDT
                     TFKEWVATVPDEELQLYFDLFFGTILDAGISSINDLASLKALEYIHHLFVQAQSLTPE
                     ERETLGRLTQLLIDTRYQAWKNR"
     gene            24810..25487
                     /locus_tag="ACL29Z_000498"
     CDS             24810..25487
                     /locus_tag="ACL29Z_000498"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000548969.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HGR0068853.1"
                     /translation="MHKILLVEDDQVIRQQVGKMLSEWGFEVVLVEDFMEVLSLFVQS
                     EPHLVLMDIGLPLFNGYHWCQEIRKISKVPIMFLSSRDQAMDIVMAINMGADDFVTKP
                     FDQQILLAKVQGLLRRSYEFGRDESLLEYAGVILNTKSMDLHYQGQVLNLTKNEFQIL
                     RVLFEHAGNIVARDDLMRELWNSDFFIDDNTLSVNVARLRKKLEEQGLVGFIETKKGI
                     GYGLKHA"
     gene            25480..26454
                     /locus_tag="ACL29Z_000499"
     CDS             25480..26454
                     /locus_tag="ACL29Z_000499"
                     /EC_number="2.7.13.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA];
                     GO_function: GO:0004673 - protein histidine kinase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0007165 - signal transduction [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HGR0068854.1"
                     /translation="MLDWKQFFLAYLRSRSRLFIYLLSLAFLVLLFQFLFASLGIYFL
                     YFFFLCCFVTILFFTWDILVETQVYRQELLYGEREAKSPLEIALAEKLEAREMELYQQ
                     RSKAERKLTDLLDYYTLWVHQIKTPIAASQLLVAEVVDRQLKQQLEQEIFKIDSYTNL
                     VLQYLRLESFHDDLVLKQVQIEDLVKEIIRKYALFFIQKGLNVNLHDLDKEIMTDKKW
                     LLVVIEQIISNSLKYTKEGGLEIYMDDQELCIKDTGIGIKNSDVLRVFERGFSGYNGR
                     LTQQSSGLVLYLSKKISEELGHQIRIESEVGKGTTVRIQFAQVNLVLE"
     gene            complement(26503..28446)
                     /gene="thrS"
                     /locus_tag="ACL29Z_000500"
     CDS             complement(26503..28446)
                     /gene="thrS"
                     /locus_tag="ACL29Z_000500"
                     /EC_number="6.1.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000608363.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004829 - threonine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006435 - threonyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="threonine--tRNA ligase"
                     /protein_id="HGR0068855.1"
                     /translation="MINITFPDGAVREFESGVTTFEIAQSISNSLAKKALAGKFNGKL
                     IDTTRAITEDGSIEIVTPDHEDALPILRHSAAHLFAQAARRLFPDIHLGVGPAIEDGF
                     YYDTDNTAGQISNEDLPRIEEEMQKIVKENFPSIREEVTKDEAREIFKNDPYKLELIE
                     EHSEDEGGLTIYRQGEYVDLCRGPHVPSTGRIQIFHLLHVAGAYWRGNSDNAMMQRIY
                     GTAWFEKKDLKNYLQMREEAKERDHRKLGKELDLFMISQEVGQGLPFWLPNGATIRRE
                     LERYIVNKELASGYQHVYTPPLASVELYKTSGHWDHYQEDMFPTMDMGDGEEFVLRPM
                     NCPHHIQVFKHHVHSYRELPIRIAEIGMMHRYEKSGALTGLQRVREMSLNDGHLFVTP
                     EQIQEEFQRALQLIIDVYEDFNLTDYRFRLSLRDPQDTHKYFDNDEMWENAQTMLRAA
                     LDEMGVDYFEAEGEAAFYGPKLDIQIKTALGKEETLSTIQLDFLLPERFDLKYIGADG
                     EDHRPVMIHRGVISTMERFTAILIENYKGAFPTWLAPHQVTLIPVSNEKHVDYAWEVA
                     KKLRDRGVRADVDERNEKMQFKIRASQTSKIPYQLIVGDKEMEDETVNVRRYGQKETQ
                     TVSVDNFVQAILADIANKSRVEK"
     gene            complement(28504..28827)
                     /locus_tag="ACL29Z_000501"
     CDS             complement(28504..28827)
                     /locus_tag="ACL29Z_000501"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000422771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MazG-like protein"
                     /protein_id="HGR0068856.1"
                     /translation="MELQELVERSWAIRQAYHELEVKHHDSKWTVEEDPLALSNDIGN
                     FQRLVMTKQGRYYDETPYTLEQKLSENIWWLLELSQRLDIDILTEMENFLSDKEKQLN
                     VRTWK"
     gene            complement(29258..29458)
                     /locus_tag="ACL29Z_000502"
     CDS             complement(29258..29458)
                     /locus_tag="ACL29Z_000502"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001826938.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0068857.1"
                     /translation="MRRFYSHLPYYLVILFFYWPLYELFLLVVSDPLTLKELYINNLL
                     FFTPLVILIVSLLYSYRFRFSL"
     gene            29696..30325
                     /locus_tag="ACL29Z_000503"
     CDS             29696..30325
                     /locus_tag="ACL29Z_000503"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)-dependent oxidoreductase"
                     /protein_id="HGR0068858.1"
                     /translation="MKLAVIAANGQAGKAIVEEVVKRGHEVTAIVRSENKSQSESIIK
                     KDLFELTKDDLTGFDAVISAFGAYTPDTLPLHSKSIELFNQLLAGTQTRFLVVGGAGS
                     LYIDETKTTRLLDTSDFPEEFKSLAKAQADELDLLRTKNNLNWTFVSPAVDFIPDGEK
                     TGNYILAGEIFTTNEKGISQISYADYAIGLVDELEKGHHIKERISLLEK"
     gene            30466..30735
                     /gene="rpsO"
                     /locus_tag="ACL29Z_000504"
     CDS             30466..30735
                     /gene="rpsO"
                     /locus_tag="ACL29Z_000504"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001018251.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S15"
                     /protein_id="HGR0068859.1"
                     /translation="MAISKEKKNEIIAQYARHEGDTGSVEVQVAVLTWEINHLNEHIK
                     QHKKDHATYRGLMKKIGRRRNLLAYLRKNDVNRYRELINSLGLRR"
     gene            31550..32164
                     /locus_tag="ACL29Z_000505"
     CDS             31550..32164
                     /locus_tag="ACL29Z_000505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000531723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CadD family cadmium resistance transporter"
                     /protein_id="HGR0068860.1"
                     /translation="MGQTIISAIGVYISTSIDYLIILIILFAQLSQNKQKWHIYAGQY
                     LGTGLLVGASLVAAYVVNFVPEEWMVGLLGLIPIYLGIRFAIVGEDAEEEEEEIIERL
                     EQSKANQLFWTVTLLTIASGGDNLGIYIPYFASLDWSQTLVALLVFVIGIIIFCEISR
                     VLSSIPLIFETIEKYERIIVPLVFILLGLYIMYENGTIETFLIV"
     gene            complement(32456..33205)
                     /locus_tag="ACL29Z_000506"
     CDS             complement(32456..33205)
                     /locus_tag="ACL29Z_000506"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000500208.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysophospholipid acyltransferase family protein"
                     /protein_id="HGR0068861.1"
                     /translation="MFYTYLRGLVVLLLWSINGNAHYHNTDKIPNQDENYILVAPHRT
                     WWDPVYMAFATKPKQFIFMAKKELFTNRIFGWWIRMCGAFPIDRENPSASAIKYPINV
                     LKKSDRSLIMFPSGSRHSNDVKGGAALIAKMAKVRIMPVTYTGPMTLKGLISRERVDM
                     NFGNPIDISDIKKMNDEGIETVANRIQTEFQRLDEETKQWHNDKKPNPLWWFIRIPAL
                     ILAIILAILTIIFSFIASFIWNPDKKREELA"
     gene            33338..35674
                     /locus_tag="ACL29Z_000507"
     CDS             33338..35674
                     /locus_tag="ACL29Z_000507"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000360031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation-translocating P-type ATPase"
                     /protein_id="HGR0068862.1"
                     /translation="MDKNKIMGLTQREVKERQAEGLVNDFTASASTSTWQIVKRNVFT
                     LFNALNFAIALALAFVQAWSNLVFFAVICFNAFSGIVTELRAKHMVDKLNLMTKEKVK
                     TIRDGQEVALNPEELVLGDVIRLSAGEQIPSDALVLEGFAEVNEAMLTGESDLVQKEV
                     DGLLLSGSFLASGSVLSQVHHVGADNYAAKLMLEAKTVKPINSRIMKSLDKLAGFTGK
                     IIIPFGLALLLEALLLKGLPLKSSVVNSSTALLGMLPKGIALLTITSLLTAVIKLGLK
                     KVLVQEMYSVETLARVDMLCLDKTGTITQGKMQVEAVLPLTETYGEEAVASILTSYMA
                     HSEDKNPTAQAIRQRFVGDVAYPMISNLPFSSDRKWGAMELEGLGIVFLGAPEMLLDS
                     EVPEAREALERGSRVLVLALSQEKLDHHKPQKPSDIQALALLEILDPIREGAAETLDY
                     LRSQEVGLKIISGDNPVTVSSIAQKAGFADYHNYVDCSKITDEELMAMAEETAIFGRV
                     SPHQKKLIIQTLKKAGHTTAMTGDGVNDILALREADCSIVMAEGDPATRQIANLVLLN
                     SDFNDVPEILFEGRRVVNNIAHIAPIFLIKTIYSFLLAVICIASALLGRSEWILIFPF
                     IPIQITMIDQFVEGFPPFVLTFERNIKPVEPNFLRRSMLRALPSALMVVFSVLFVKIF
                     GTSQGWSELEISTLLYYLLGSIGFLSVFRACMPFTLWRVLLIVWSVGGFLATALFPRI
                     QKLLEIATLTGQTLPVYGVMMLVFTVIFILTSRYQARK"
     gene            35776..36453
                     /locus_tag="ACL29Z_000508"
     CDS             35776..36453
                     /locus_tag="ACL29Z_000508"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000624068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (adenine(22)-N(1))-methyltransferase TrmK"
                     /protein_id="HGR0068863.1"
                     /translation="MISKRLELVASFVSQGAILLDVGSDHAYLPIELVERGQIKSAIA
                     GEVVEGPYQSAVKNVEAHGLKEKIQVRLANGLAAFEETDQVSVITIAGMGGRLIARIL
                     EEGLGKLANVERLILQPNNREDDLRIWLQDHGFQIVAERILEEAGKFYEILVVEAGQM
                     KLSASDVRFGPFLSKEVSPVFVQKWQKEAEKLEFALGQIPEKNLEERQVLVDKIQAIK
                     EVLHVSK"
     gene            36440..37237
                     /locus_tag="ACL29Z_000509"
     CDS             36440..37237
                     /locus_tag="ACL29Z_000509"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000881127.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0051540 - metal cluster binding [Evidence
                     IEA];
                     GO_process: GO:0008150 - biological_process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Nif3-like dinuclear metal center hexameric
                     protein"
                     /protein_id="HGR0068864.1"
                     /translation="MLASEVIQAYEAFCPQEFSMEGDSCGLQIGTLDKGIQRVMVALD
                     IREETVAEAIEKGVDLIIVKHAPIFRPIKDLLASRPQNQIYIDLIKHDIAVYVSHTNI
                     DIVENGLNDWFCQMLGIEETTYLQETGPERGIGRIGNIQPQTFWELAQQVKQVFDLDS
                     LRMVHYQENDLQKPISRVAICGGSGQSFYKDALAKGADVYITGDIYYHTAQDMLSDGL
                     LALDPGHYIEVLFVEKIAALLTQWKEKKGWELEILPSQASTNPFRHI"
     gene            37254..38357
                     /locus_tag="ACL29Z_000510"
     CDS             37254..38357
                     /locus_tag="ACL29Z_000510"
                     /EC_number="1.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397627.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HGR0068865.1"
                     /translation="MKKVAIIGAGIVGATAAYYLSRESDLEVTVFDHEQGQATKAAAG
                     IISPWFSKRRNKAWYKMARLGADFYVDLLADLEKSGQKIDFYQRSGVFLLKKDESKLE
                     ELYQLALQRREESPLIGQLAILDQASANELFPGLQGFDRLLYASGGARVDGQLLVTRL
                     LEASHVKLVKEKVTLTLLSSGYQIGEEVFDQVILATGAWLGDMLEPLGYEVDVRPQKG
                     QLRDYQLAQDMEDYPVVMPEGEWDLIPFAGGKLSLGATHENDMGFDLTVDEPLLQQME
                     EAALPHYPVLARATSRAERVGIRAYTSDFSPFFGQVPELAGVYVASGLGSSGLTTGPI
                     IGYHLAQLIQDKELTLDPLNYPIENYVKRVKSE"
     gene            38364..38555
                     /locus_tag="ACL29Z_000511"
     CDS             38364..38555
                     /locus_tag="ACL29Z_000511"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0068866.1"
                     /translation="MKIKEQTRKLAAGYSKHCFEVVYRTDEVSSKHCFEVVDRTDEVS
                     NHTHGKATLTWFELDFRRV"
     gene            38658..39677
                     /gene="galE"
                     /locus_tag="ACL29Z_000512"
     CDS             38658..39677
                     /gene="galE"
                     /locus_tag="ACL29Z_000512"
                     /EC_number="5.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006153709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003978 - UDP-glucose 4-epimerase activity
                     [Evidence IEA];
                     GO_process: GO:0006012 - galactose metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose 4-epimerase GalE"
                     /protein_id="HGR0068867.1"
                     /translation="MQEKILVTGGAGFIGTHTVIELIQAGHQVVVVDNLVNSNRKSLE
                     VVERITGVEIPFYEADIRDTVTLRDIFKQEEPTGVIHFAGLKAVGESTRIPLAYYDNN
                     IAGTVSLLKAMEENNCKNIIFSSSATVYGDPHTVPILEDFPLSVTNPYGRTKLMLEEI
                     LTDIYKADSEWNVVLLRYFNPIGAHESGDLGENPNGIPNNLLPYVTQVAVGKLEQVQV
                     FGDDYDTEDGTGVRDYIHVVDLAKGHVAALKKIQKGSGLNVYNLGTGKGYSVLEIIQN
                     MEKAVGRPIPYRIVERRPGDIAACYSDPAKAKAELGWEAELDITQMCEDAWRWQSKHP
                     NGFED"
     gene            39679..40632
                     /locus_tag="ACL29Z_000513"
     CDS             39679..40632
                     /locus_tag="ACL29Z_000513"
                     /EC_number="2.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014931854.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016757 - glycosyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HGR0068868.1"
                     /translation="MMISIIVPCLNEEEVLPLFYQALEALLPDLETEIEYVFVDDGSS
                     DGTLELLKAYREQNPAVHYISFSRNFGKEAALYAGLQYATGDLVVVMDADLQDPPSML
                     FEMKNVLDKNVDLDCVGTRRTSREGEPFFRSFCAVLFYRLMQKISPVALPSGVRDFRM
                     MRRSVVDAILSLTESNRFSKGLFAWVGFKTHYLDYPNVERQAGKTSWSFRQLFFYSIE
                     GIVNFSDFPLTIAFVAGLLSCFLSLLMTFFVVVRTLILGNPTSGWTSLMAVILFLGGI
                     QLLTIGILGKYISKIYLETKKRPLYLIKEKSDLPDFTEKIK"
     gene            complement(40694..40900)
                     /locus_tag="ACL29Z_000514"
     CDS             complement(40694..40900)
                     /locus_tag="ACL29Z_000514"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001843159.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005506 - iron ion binding [Evidence IEA];
                     GO_function: GO:0009055 - electron transfer activity
                     [Evidence IEA];
                     GO_function: GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ferredoxin"
                     /protein_id="HGR0068869.1"
                     /translation="MKITLIPERCIACGLCQTYSDLFDYHDNGIVRFYDDPDQLEKEI
                     SPSQDVLEAVKNCPTRALIGNQEA"
     gene            40952..41428
                     /locus_tag="ACL29Z_000515"
     CDS             40952..41428
                     /locus_tag="ACL29Z_000515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399345.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SAG1386/EF1546 family surface-associated
                     protein"
                     /protein_id="HGR0068870.1"
                     /translation="MAKEPWQEDIYDQEESRAGRRHRNHGGADRMANRILTILASIFF
                     VIVVVMVIVLIYLSSGGSNRTVALKDFHDSDASVVQISSSSSSQPEQSSEPESTSSSS
                     EEAANPEGTIKVLAGEGEAAIAARAGISIAQLEALNPGHMATGSWFANPGDVIKIK"
     gene            41437..42108
                     /gene="cmk"
                     /locus_tag="ACL29Z_000516"
     CDS             41437..42108
                     /gene="cmk"
                     /locus_tag="ACL29Z_000516"
                     /EC_number="2.7.4.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000849376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004127 - (d)CMP kinase activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0015949 - nucleobase-containing small
                     molecule interconversion [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="(d)CMP kinase"
                     /protein_id="HGR0068871.1"
                     /translation="MKTIQIAIDGPASSGKSTVAKIIAKDFGFTYLDTGAMYRAATYM
                     ALKNQLGVEEVEALLALLDQHPISFGRSETGDQLVFVGDVDITHPIRENEVTNHVSAI
                     AAIPEVREKLVSLQQEIAQQGGIVMDGRDIGTVVLPQAELKIFLVASVDERAERRYKE
                     NIAKGIETDLETLKKEIAARDYKDSHRETSPLKQAEDAVYLDTTGLNIQEVVEKIKAE
                     AEKRM"
     gene            42239..42577
                     /locus_tag="ACL29Z_000517"
     CDS             42239..42577
                     /locus_tag="ACL29Z_000517"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002920966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ribbon domain-containing protein YjdM"
                     /protein_id="HGR0068872.1"
                     /translation="MNNLPNCPKCNSEYVYEDGALLVCPECAHEWNPAEVAEVEEGLV
                     AIDANGNKLADGDIVTLIKDLKVKGAPKDLKQGTRVKNIRIVEGDHNIDCKIDGFGAM
                     KLKSEFVRKI"
     gene            42580..43209
                     /locus_tag="ACL29Z_000518"
     CDS             42580..43209
                     /locus_tag="ACL29Z_000518"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000033944.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Pr6Pr family membrane protein"
                     /protein_id="HGR0068873.1"
                     /translation="MSKHYKLVFYSRIFLFLAAFTGVYLEITRHGGFGMLLYYTVLSN
                     LLVTIFTLYLLKVMSRVGENWQRPSLLRLKGGVTMSIMITCVIYHFLLAPIATNFYTL
                     ENFLCHYIVPIWFLADTLFFDKQGQYKIWDPAVWTILPFLYMMFALFNGLVLKLNIPN
                     AKDNPFPYFFLNVNKGWNVVFKWCLIIFVAYMVAGFIFYFIKQIKRKSS"
     gene            43449..44600
                     /locus_tag="ACL29Z_000519"
     CDS             43449..44600
                     /locus_tag="ACL29Z_000519"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000808687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HGR0068874.1"
                     /translation="MKQFLERASILALSLVLITSFSISSALPAMFDYYQGYSKEQIEL
                     LVSLPSFGIMMMLLLNGFLEKIFPERLQISLGLLILSLSGTAPFWYQAYPFVFGTRLL
                     FGLGLGMINAKAISIISERYQGKRRIQMLGLRASAEVVGASLITLAVGQLLAFGWTAI
                     FLAYSAGFLVMPLYLLFVPYGKSKKEVKKRAKEASRLTREMKGLIFTLAIEAAVVVCT
                     NTAITIRIPSLMVERGLGDAQLSSFVLSIMQLIGIVAGVSFSFLISIFKEKLLLWSGI
                     TFGLGQIVIALSSSLWVVVAGSVLAGFAYSVVLTTVFQLVSERIPAKLLNQATSFAVL
                     GCSFGAFTTPFVLGAIGLLTHNGMLVFSILGGWLIVISIFVMYLLQKRA"
     gene            44913..45662
                     /gene="truA"
                     /locus_tag="ACL29Z_000520"
     CDS             44913..45662
                     /gene="truA"
                     /locus_tag="ACL29Z_000520"
                     /EC_number="5.4.99.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011999919.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0009982 - pseudouridine synthase activity
                     [Evidence IEA];
                     GO_process: GO:0001522 - pseudouridine synthesis [Evidence
                     IEA];
                     GO_process: GO:0009451 - RNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(38-40) synthase TruA"
                     /protein_id="HGR0068875.1"
                     /translation="MTRYKATISYDGYAFDGFQRQPHARSVQEEIEKTLTRLNKGQTI
                     TVHGAGRTDSGVHALGQVIHFDLPYQMDEEKLRFALDTQSPEDIDVISIELVADDFHC
                     RYAKHSKTYEFIVDRGRPKNPMRRHYATHFPYPLDVERMQIAIKKLEGTHDFTGFTAS
                     GTSVEDKVRTITEASLIVDETGQFLTFTFSGNGFLYKQIRNMVGTLLKIGNNRMPVEQ
                     IALILEKKDRQLAGPTAAPNGLYLKEIRYEE"
     gene            45652..46425
                     /locus_tag="ACL29Z_000521"
     CDS             45652..46425
                     /locus_tag="ACL29Z_000521"
                     /EC_number="2.7.1.49"
                     /EC_number="2.7.4.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008972 - phosphomethylpyrimidine kinase
                     activity [Evidence IEA];
                     GO_process: GO:0009228 - thiamine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional hydroxymethylpyrimidine
                     kinase/phosphomethylpyrimidine kinase"
                     /protein_id="HGR0068876.1"
                     /translation="MKNNRILALSGNDIFSGGGLSADLATYTLNGLHGFVAVTCLTAL
                     TEKGFEVFPTDDTIFQHELDSLRDVEFGGIKIGLLPTVSVAEKALDFIKQRPGVPVVL
                     DPVLVCKETHDVAVSELCQELIRFFPYVSVITPNLPEAELLSGQEIKTLEDMKTAAQK
                     LHDLGAPAVIIKGGNRLSQDKAVDVFYDGQTFTILENPVIQGQNAGAGCTFASSIASH
                     LVKGDKLLPAVESSKAFVYRAIAQADQYGVRQYEANKNN"
     gene            46403..46864
                     /locus_tag="ACL29Z_000522"
     CDS             46403..46864
                     /locus_tag="ACL29Z_000522"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000814967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HGR0068877.1"
                     /translation="MKQTKTTKIALVSLLTALSVVLGYFLKFPTPTGILTLLDAGVFF
                     AAFYFGSREGAVVGGLASFLIDLLSGYPQWMFFSLVNHGLQGFFAGFKGKSQWLGLIL
                     ATIAMVGGYALGSTLMNGWAAALPEILPNFMQNMVGMIVGFILSQSIKKIK"
BASE COUNT        13725 a         8742 c        10728 g        13887 t
ORIGIN      
        1 aaaaaaggag attttattat gaaattaaaa acacttgctt taattagtgg tatcgtcggt
       61 cttgtgggag gaattttact tcttattggt ccttttgtct tgttgggaac aacggtaaac
      121 acagctgcta caactcttaa tggaggagct actgcagggg ctttttcagg tgttgcctta
      181 ctcttgaatg ccttgaagat tgaaaatctt gttcttggta tcattgctat tgtttactat
      241 aaaggagata agcgtgtagg tgcagctccg tctgtactaa tgattgtttc tggtggagtt
      301 agtctcattc cattcttagg atgggttggg gggattcttg ctattatcgg aggatctcta
      361 ttccttgcaa cattgaagaa attcaaatca gaagaataaa aggtatttta gcatgaaaag
      421 aacaaaaaag tttatcggta taggagtagc tctattatct ctttctcttc tagttgcatg
      481 tggaacataa agttcaaaga atacttcaac aagtaatgat gagaagacag tagcaacatc
      541 caatagttca aaagaaacaa tcactttcga tacaccggtt gtaacagacg atgcgattga
      601 atcaatacgc acttatgcag attatataga tctttataaa aatatttttg atgattattt
      661 tactaaagct gaggaaggtt tcaaaggcac agctatggaa aataatgact cgtttactaa
      721 actaaaagag tcaactcaaa aattattcga tgcgcagaaa aaaaggttaa ataatgaaga
      781 tagaatagaa acaaccaaaa acaatgtgat tgccaaacat tgtcaaacag tcctttcctt
      841 tttggttttg actagctttt ttgtgaaaaa ttgtgtaaaa tagaatagat aaacgagggg
      901 aaacctcgga aaatttaaag gagaatccat ctaatggtaa aattggtttt tgctcgccac
      961 ggtgagtctg aatggaacaa agctaacctt ttcactggtt gggctgatgt tgatttgtct
     1021 gaaaaaggta cacaacaagc gattgacgct ggtaaattga tcaaagaagc tggtatcgaa
     1081 tttgaccaag cttacacttc agtattgaaa cgtgctatca aaacaactaa cttggctctt
     1141 gaagcttctg accaattatg ggttccagtt gaaaaatcat ggcgcttgaa cgaacgtcac
     1201 tacggtggtt tgactggtaa aaacaaagct gaagctgctg aacaatttgg tgatgagcaa
     1261 gttcacatct ggcgtcgttc atacgatgta ttgcctccaa atatggaccg tgatgatgag
     1321 cactcagctc acacagaccg tcgttatgct tcacttgacg actcagtaat cccagatgct
     1381 gaaaacttga aagtgacttt ggaacgtgct cttccattct gggaagataa aatcgctcca
     1441 gctcttaaag atggtaaaaa cgtattcgta ggagctcacg gtaactcaat ccgtgccctt
     1501 gtaaaacaca tcaaaggttt gtcagatgat gagatcatgg acgtggaaat ccctaacttc
     1561 ccaccattgg tattcgaatt cgatgaaaaa ttgaacgttg tttctgaata ctaccttgga
     1621 aaataaaaaa ttgtaagcct aggattgatt tctaggcttt ttatgttagt atggaagtat
     1681 gataaggaat aaaaaacaag attatgtact ggcctacaag caaccagctt caaccactta
     1741 catgggttgg gaagaagaag ctttaccgat aggtaatggt tctttaggag caaaagtatt
     1801 tggccttata gggtctgaac ggattcaatt taatgaaaaa agtctctggt ctggaggtcc
     1861 acttcctgat agttcagatt atcagggtgg aaatcttcag gatcagtatg tttttttagc
     1921 tgagattcgg caggctttgg agaagagaga ttacaatctg gctaaggaac tggctgagca
     1981 gcacctaatt gggccaaaaa cgagtcaata tgggacctat ctgtcttttg gggatattca
     2041 cattgagttc agccagcaag gtacgacttt gtctcaggtg acggactatc agagacagtt
     2101 gaatattagt aaggcacttg cgacgacttc ttatgtctat aagggaacgc gatttgaacg
     2161 tgaagctttt gcgagttttc cagatgatct cttggttcaa tgttttacta aggaagggtt
     2221 ggaaactcta gattttacta tagaactatc cttgacctgt gatttggctt ctgatggaaa
     2281 gtatgagcag gaaaaatctg attacaagga gtgtaagttg gatattactg attctcatat
     2341 cttgatgaag ggaagagtta aggataatga tctgcggttt gctagttatc tagcttggga
     2401 aacggatgga gatattagag tttggtcaga tagggttcag atatcaggag ccagttatgc
     2461 caatctcttc ttggccgcta agacggattt tgcccaaaat cctgctagca attatcgcaa
     2521 gaaactagat ttagagcaac aggtgataga cttggtggac acagctaaag aaaagggcta
     2581 tacccaattg aaatcaaggc atatcgagga ctaccaagcc ttattccagc gtgttcaatt
     2641 ggatttggaa gctgatgttg acgcatccac tacagatgat ttgttaaaaa attataagcc
     2701 acaagaaggg caggctttgg aggagctgtt cttccagtat ggacggtatt tattgattag
     2761 ttcgtccaga gactgcccag atgctctacc agctaaccta cagggagtct ggaatgcggt
     2821 cgacaatcct ccttggaatt cggactatca cttaaatgtc aatctgcaga tgaattattg
     2881 gccagcctat gttaccaatc tcctagagac ggtctttcca gtcatcaact atgtagatga
     2941 tttgcgtgtc tatggtcgtc tagcggctgt aaagtatgca ggaatcgtct ctcagaaagg
     3001 tgaggaaaat ggttggttgg ttcatactca agcgactccc tttggttgga cggcacctgg
     3061 ttgggattac tattggggtt ggtcaccagc tgccaatgcg tggatgatgc aaaccgttta
     3121 tgaagcctat tcattttata gggaccaaga ctatcttagg gagaaaattt atcccatgtt
     3181 gagggaaacg gttcgttttt ggaatgcctt tttacataag gatcagcagg cgcagcgttg
     3241 ggtgtcttct ccgtcttatt ctccagaaca tgggccgatt tcgattggca atacctatga
     3301 ccaatctctg atttggcagt tatttcatga ttttattcag gctgctcagg aattgggact
     3361 ggatgagaac ttgttgactg aggttaagga gaagtctgat ttactaaatc ctttgcaaat
     3421 cactcaatct ggtcgaatca gggagtggta tgaggaggaa gagcagtatt ttcaaaatga
     3481 gaaagtggag gcccagcacc ggcacgcttc ccatctagtg ggactctatc ctggcaatct
     3541 ctttagctac aagggacaag agtatattga agcggcgcgt gctagcctca atgatcgtgg
     3601 agatggcggc acaggctggt ccaaggctaa taagatcaat ctctgggcgc gtttgggaga
     3661 tggcaatcga gcccataaat tattggcaga gcagttaaag atatccacct tgccaaatct
     3721 ttggtgtagc catcctcctt ttcagataga tggtaatttt ggtgctacta gtggcatggc
     3781 agaaatgtta ctccagtctc atgcagctta tctggtacct ctagctgccc tacctgatgc
     3841 ttggtcaaca ggttctgttt caggcttaat ggcacgtgga cattttgaag tgagcatgag
     3901 ctgggaagat aaaaaactct tacagttgac cattttatca aggagtggag gagatttgcg
     3961 agtttcttat ccagatattg agaagagtgt gattaaaatg aatcaagaaa aaataaaagc
     4021 gaaatgcatg gggaaagatt gtatttcggt ggcaacagca gaaggtgatc ttgttcaatt
     4081 ttatttttaa gaagatgtta taaggcagta atttgaaact gccttttaat aaggatttaa
     4141 gaatataggc agtttccaac tagttgaaaa agcgttataa tgataatagg aagtaatact
     4201 caatgaaaat caaagagcac aaactaggaa gctagccgca ggttgctcaa aacagtgttt
     4261 tgaggttgta gatggaagct gacgtggttt gaagagagat tttcgaggag tataatttgt
     4321 ttgatagagg gtgggtctga tggcttatat tgagatgaaa cactgttaca agcgttatca
     4381 ggttggggac acggagattg tggccaatcg tgatgtgaat tttgagattg aaaaggggga
     4441 gctggttatt atccttggtg cttcaggtgc aggcaagtca acagttctta accttcttgg
     4501 gggaatggat accaatgatg aaggggaaat ctggattgat ggtgttaata ttgcggatta
     4561 tagttcccac cagcgcacca attaccgtag aaatgatgtg gggtttgttt ttcagtttta
     4621 taatctagtt tctaatctga cagctaagga aaatgtggaa ctggcttctg aaattgtgac
     4681 agatgccttg aatcctgctc aggttttgac agatgtaggt ctggctcatc gtctcaataa
     4741 ctttccagcc cagctttctg gaggggagca acagcgagtc tccattgcac gcgcggtagc
     4801 caaaaatcct aaaattcttc tttgtgatga accgactgga gccttggatt atcagacggg
     4861 caagcaggtt ttgaaaattc tccaagatat gtctcgtcaa aagggagcga cggtgatcat
     4921 cgtgactcat aatggagctt tggcgcccat tgctgatcgc gtgattcata tgcacgatgc
     4981 cagtgtcaag gatgtggtgc tcaaccagca tcctcaggat attgacagtt tggagtacta
     5041 gcatgatcaa gcgaaaaact tattggaagg acttaattca gtccttcaca ggctccaagg
     5101 ggcgtttttt atccatcttg atcctgatga tgttgggatc tctagcctta gtaggcctca
     5161 aagtaaccag tcccaacatg gagacgacag ctaatgctta tttaacaact gctcaaacct
     5221 tggatttggc agtcatgtct aactatggct tggatcaagc agaccaagaa gaactaaaac
     5281 agacggaggg cgcagaggtc gagtttggct atttgacaga tgtgactatg gataatgggc
     5341 aggatgccat tcggctgtac tccaaaccag agcgaatttc aacctttcag ctaagaaagg
     5401 gacgacttcc tcagtcagac aaggaaatcg ctttggccac tcatttgcaa ggccaataca
     5461 gcgtgggaca ggagattagt tttaaagaaa aagaagaggg tcattcctct ttaaaagacc
     5521 atacttatac cattactggt tttgtggatt cggctgaaat cctctcccag cgagatatgg
     5581 gctacgcagg aagtggaagt gggactctga cagcctatgg ggtgatttta cctagtcaat
     5641 ttgatcagaa agtctacaat atagctcgtt tgaaatatca agatttagca ggtttaaatg
     5701 ccttttcatc agcttatgaa gaaaaatcca agcaacatca ggaagagctt gaacaaattt
     5761 tatcagataa tggcaaggta cgtctgcaac ttttgaaaaa agaaggacaa gagtctctag
     5821 acaaggggca agagaccctt gacaaggctc agactaattt gcaggaaggc aagcgtcgtt
     5881 tagcagctgc tcaagctcgt atacaggctc aagaaagtca actagccttg tttcctcaag
     5941 ttcagagaga gcaggctagt gctcaactta cccaagccaa gcaggaattg ggcaaggaag
     6001 aggccaaact aaagcaagct gaacaaaatc tagcccaaga aaaggaaaaa ttagaaaaac
     6061 atcagcaagt cttggacgat ttggcggagc caaggtatca ggtctataat cgtcagacca
     6121 tgccaggtgg tcagggctat cttatgtata gcaatgcttc atccagtatt cgagcagtgg
     6181 gcaatatctt tcctgtggta ctttatgccg tagcagccat ggtgaccttt acgaccatga
     6241 ctcgctttgt agacgaagag cgaactcatg cagggatttt taaggccttg ggttatcgta
     6301 gtaaggatat tatcgccaag tttctccttt atggactagt agctgggact gtcggaacgg
     6361 ctctaggtag tatacttggt cattatttgc tagccaatgt aatttcaagt gtcattacaa
     6421 aaggcatggt ggtgggagaa actcagattc agttctattg gacctatagc ttactagctc
     6481 ttgtcttgag cttgttggcg agtgtgttac cagcctatct ggtggcttgg agggaacttc
     6541 atgacgaagc agcccagctt ctacttccta aacctcctgt caaaggagct aaaatcttat
     6601 tggagcgtat cggttttatc tggcgtcgtc tcagttttac tcataaggta acagctcgca
     6661 acatctttcg ttataagcag agaatgttga tgacaatctt tggtgtggca ggttctgtag
     6721 ctctgctctt tgcaggtttg ggaatccaat cttctgtagc aggagttccg tctaaacagt
     6781 ttcaacaaat ccaacagtat cagatgcttg tctctgaaaa tcctagtgcg accaatcagg
     6841 acaaggtaga gctagcagaa gtgttgaaag ggcaggagat actagcctac cagaaaatct
     6901 attctaaagc gctagacaag gatttcaaag gcaaggctgg tcttcaaaac attactctta
     6961 tgatgataga gaaggaagat ttgactccct ttatccatct tcaacatcat cagcaggagc
     7021 tgacattaaa agatggcatc gttattacag ctaaactcgc ccagctggca ggtgtcaagg
     7081 ttgggcagac tttagaaatt gaaggtaagg aactaaaggt cgctgctatt actgagaact
     7141 acgttggtca ctttatttat atgagtcagg ctagctatga gcaactttac ggacagctac
     7201 cccaagccaa cacttatctg gtctcattaa gggataccag tgcaactagt atcgaaagtc
     7261 aggcgggctt gcttatgaat caatctgcgg tgtccagcgt tgtccaaaat gcttcagcca
     7321 ttcgactctt cgactctatc gctagctcac tcaatcagac catgaccatc ttggtcatcg
     7381 tatcggttct attagctatt gtcatccttt acaatctgac caatatcaac gtagctgaga
     7441 gaatccgtga actctccact atcaaggttc tcggttttca taataatgaa gtcaccctct
     7501 acatttaccg tgagacgatt gtgctgtccc ttgtgggaat cgtacttggt ctggtagctg
     7561 gtttctattt acaccaattt ttgattcaaa tgatttcgcc tgcgactatt ctcttttatc
     7621 cgcaggtagg ctgggaagtc tatgtaatcc cagtggcaac agtaagcatc attttgacct
     7681 tgcttggttt cttcgtcaat tattatctga gaaaggttga tatgttagaa gccctgaaat
     7741 ctgtagagta aggtagttat ttttagctga ttgaacttct atttactaat attcaaaaat
     7801 cctccgtttc aaagagcagg gagctctttg tgacagagga ttttttctat agggctttag
     7861 cagctgcaat tgcggcttcg aagtttggct cagaattgat attatccacg tattcaacgt
     7921 agcgaatcgt attgtcagta tcgaggacaa agactgcgcg tgctaatagg tgccattcgt
     7981 tgatcaagag ggcataatcg cgcccgaaag aatggtcaaa gtagtctgaa agcataatgg
     8041 cattgtcaag gccttcagca ccgcaccaac gtttttgagc aaaaggtagg tccattgaaa
     8101 cagtcaatac gaccgtgttg tccagtccag ccaattcttc attaaaacga cgtgtttgag
     8161 ttgagcagat acctgtatcg atagaaggaa cgacactcaa gacttttttc ttgccatcaa
     8221 aatcagccag agatttttta gaaagatctg ttgtagtaag agaaaaatca agcgccttgt
     8281 cgccgacttg tagttgttta cctgtaaagc tcacaggatt tccgagaaaa gttaccatag
     8341 gatactctaa tcttttttct tccattgtat ctaaaacagt cagaattttc caatgatttg
     8401 accggaaatg tgtgcataga aaaaacgcca gctcacatga gaatgacgtt tttcagaggc
     8461 ttattttgcc aatccttcag caatcttgtc aaggttgtat ttcatcatgc tgtagtagct
     8521 gtcgccttct ttaccttgtt ctgcgataga gtcagtaaag atttgtgcgt agattgggat
     8581 gtttgtgtct tgagaaacag ttttcattgg acggtcatcc acacttgatt ctacaaagag
     8641 tgatggaact tttgtttggc gaagtttttc aaccaaggtc ttgatttgtt caggagttcc
     8701 ttcttcttca gtattgattt cccagatgta ggcacttggg acaccatagg ctttagagaa
     8761 gtatttgaat gctccttcgc tggttacaat gagtttcttt tcagcaggga tcttattaaa
     8821 tttatcctta ctttctttat caagtttgtc taacttatca gtatattctt tgagattttt
     8881 ttcatagaat tctttattgt tagggtcttt ggcgctcaat tgtttggcga tatttttagc
     8941 aaaaataata ccgttttcaa ggttaagcca agcgtgtggg tcttcttttc ctttttcatt
     9001 ttgaccttca aggtagataa catcaacgcc gtcgctgact gcgaagtagt ctttgttttc
     9061 agttttcttg gcattttcta ccaattttgt aaaccaagca ttgccacctg tttcaaggtt
     9121 gataccgtta tagaaaatca aatcagcctc agaagttttc ttaacgtctt caggaagtgg
     9181 ttcgtattcg tgtgggtctt gcccaatcgg aacgatacta tgaaggtcaa ttttgtcacc
     9241 agcaatattt ttagtaatat cagcgatgat tgagtttgta gcaacaactt ttagtttttg
     9301 accagaagtt gtatcttttt ttccgctagc acatgctaca agaatgattg cagaaagaaa
     9361 gagaacgagt aatgtaccta attttttcat tagatcctcc aatttattag ggctttgccc
     9421 cttattttaa caaatgttta tttttcagtt tcaaatatcg ttgtttggga gcgataaaga
     9481 agctaatgag aaagaaacta gcagctgtaa gcacgatact agaacctgcc gcaacattaa
     9541 aactatagcc aataaagagt cccaaaactg aagcagtagc tccgaaggtt gaggaaagga
     9601 aaatcatact tttcagacta ttagcataca gataagcagt tgcagctggg gtaatcagca
     9661 tggctacaat caggatagtt ccgacacttt gcatggctgt cacagacacg agagtcagga
     9721 gtaccatgag aaggtagtga tagaaattga caggcattcc catggcttta gccaagagtt
     9781 catcaaagga agttatcaag agttgcttga agaaaatcca gattaacaag aggatggctg
     9841 cccccacacc catagtaata aacatatccg tatcttggac ggccaggata ttaccaaaaa
     9901 ggatatggaa aaggtcagtt gaacttttag cgacaccaat caagatgata ccgagggcta
     9961 agaaagaaga aaaggtaatg ccgatggcgg tatcgctttt gataatcgag tttcctttga
    10021 tgtaggtaat gatgatggca gctagcaatc caaagacaat ggctccgata aagaagtcaa
    10081 ggcccaagat gaaggagagg gctacacctg gtaagacagc atgtgaaatg gcatctccca
    10141 tgagtgacat cccgcgtaga ataatgaaac atcccacagc tccagctaca atcccgacga
    10201 caatagctgt tatcaaggca ttttgtagga aatggaattt ttgcaatcca tcgataaatt
    10261 ctgcaatcat aggtcacctc cattgaaaaa gagttgatta ccgtaagctt cttttagatt
    10321 ggtttcggta aaagtttctt ttgttggacc aaaggcaatc acttctcgat tgacaagtaa
    10381 gacttgatcg aagtagtggg gaatcttgct gaggtcgtgg tgaacgatga gaaccgtctt
    10441 cccagctttt ttcaaatctc tcagcgtatt catgatgatt tcctcactga cagagtcaat
    10501 cccagcaaag ggttcatcca agaggatata gtcggcttcc tgcaccaaac atctggcaat
    10561 caagacccgc tggaattgac ctccagacag ttgactaatt tgacgttcag cgtagtcagc
    10621 taggccgacg atttcaaggg cctcttgcac tttcttccaa tgtttagcct ttaaacttcg
    10681 aaagagagga atagagggaa atagtcctaa cgagacgcat tccttgacct tgatgggaaa
    10741 gttgtagtcg atattgattt tttgttcgac ataggcaatt cggtgtaagg attttttaac
    10801 ttccttgtca tcgagaaatg cctgaccttg atgtgggata attcccagca taccttttaa
    10861 tagtgttgat ttcccagcgc cgtttggacc aatgatgccg gtaattgttg gtccatggag
    10921 cactagtgaa atatccttaa gtgccaacgt ttctttgtag gagacactga ggttttcgat
    10981 acgtatcata aacttgtatt cctcctgtct cttaatatac attaaaaaaa aaattaagtc
    11041 aagttaattt ttgaaaaaat taaaataata actgaaaaat agattctaaa gataactttc
    11101 aggataaatt tctaaattat aaaacgcata gtatcaagtg taaaaaactt ggaattatgc
    11161 gttttatcat ggaaagattt tttataatag ctaaaaaata atagttaaat ggttattaat
    11221 tgcattccct agtgattttt gttaagataa atgcaaatac aaatgaaagc gagaacaaga
    11281 tgacacgtta tcaagatgat ttttatgatg ctatcaatgg agaatggcaa cagacagctg
    11341 aaatcccagc agataagtct caaacaggag gttttgttga tttagaccag gaaattgaag
    11401 acctgatgct ggcgacaaca gacaagtggt tagcaggtga agaagtgcct gaggatgcta
    11461 tcttggaaaa ctttgtcaaa taccaccgcc tagttcgtga ttttgacaag agagaagctg
    11521 acggtatcac acctgtctta ccactcctta aagaattcca agaattggaa acttttgcgg
    11581 attttacagc taaactagca gagtttgagc ttgcaggaaa accaaacttc cttccttttg
    11641 gtgtatcgcc agactttatg gatgctagaa tcaatgttct atgggctagc gctccaagca
    11701 caatcttgcc agatacgacc tactatgcag aagaacatcc tcagcgcgaa gagctcttga
    11761 ctctttggaa agaaagcagc gcaaatctcc tcaaggctta tgatttctct gatgaagaaa
    11821 ttgaagactt gctagaaaaa agacttgaat tggaccgccg agttgcggca gtggtgctct
    11881 ctaatgaaga aagttcagaa tatgctaaac tctatcatcc atattcttac gaagatttca
    11941 agaaattcgc gcctgcccta cctttggatg acttcttcaa agcagttatt gggcaattac
    12001 cagacaaggt tattgtagac gaggaacgtt tctggcaagc agcagagcaa ttttacagtg
    12061 aggaagcctg gtctctcctt aaagcaacct tgattttgag tgttgtcaat ctttcaacca
    12121 gctatttaac agaggatatc cgtgttttgt ctggtgccta cagccgtgcc ctttctggag
    12181 ttccagaggc aaaagataag gtcaaagcag cttatcatct agcacaggaa cctttcaagc
    12241 aagccctggg gctttggtac gcccgtgaga agttctctcc agaagccaag gcggatgtgg
    12301 agaaaaaagt ggcaaccatg attgatgtct ataaggagcg tctgcttaag aatgactggc
    12361 tcactccaga aacctgtaaa caggctatcg tgaagctcaa tgtgatcaaa ccttatattg
    12421 gctatccaga agaattgcct gcacgttaca aggataaggt agtgaatgaa actgccagtc
    12481 tttttgagaa tgctctagcc tttgcgcgtg tggaaatcaa gcacagttgg agtaagtgga
    12541 accagcctgt agactataag gaatggggca tgcctgctca tatggtcaat gcctactaca
    12601 atcctcagaa gaacctgatt gtctttccag cggccatttt acaggcgcct ttctatgact
    12661 tgcatcagtc atcttctgct aactacggtg gtattggggc agtgattgcc catgaaattt
    12721 cccacgcctt tgatactaac ggggcttcct ttgacgaaaa tggtagcctc aaggattggt
    12781 ggacagagag cgactatgct gccttcaagg agaaaacaca aaaagtcatt gaccaatttg
    12841 atggacagga ttcttatgga gcaaccatta acggtaaatt gactgtatca gaaaacgtgg
    12901 ctgacttggg aggaatcgca gcagcgcttg aagcagctaa gagagaagca gacttctcag
    12961 cagaagagtt cttctacaac ttcggtcgca tctggcgcat gaaaggtcga ccagaattta
    13021 tgaaactttt ggctagcgtc gatgtgcacg caccagccaa actccgtgtc aatgtgcaag
    13081 taccaaactt cgacgatttc tttacaacct atgatgtcaa agaaggagac ggaatgtggc
    13141 gttcaccaga ggagcgcgtg attatttggt aatacaaaaa atctagtcat cagaaaaaag
    13201 gcatccaatc acgtgtgaaa accttgatag gatgcctttt gtaatagaaa gatttgctgg
    13261 atagtttact taaatttcga ttgtcatcat cttgctagaa aaagggattg aaggcctttt
    13321 cgtgagcgat agtagtagct ggaccatgtc ctggatagac atcgtagttt ggtagggtga
    13381 agagttgggt ctggatacta tgaaggagtt gctccatgct accagtcgga aggtcggtcc
    13441 gtccgatagt ttcgcggaat agagcatctc ccgtcaagac taggtgagca tcaggaaaga
    13501 ctagggaaac accaccgata gagtgccctg gggtcggtag aaccttaaaa cgaaattcct
    13561 ctagttggta ttcttcgtga aagacaaagg tgtgttctgc aggttttgtg accacatctg
    13621 ccatatcatc gtggcgaggg agaccggaga gattatcgac aggagtgtag agccagctgg
    13681 cttcgctctc tgcgatatag acaggaggat tgccaaacgt ctcgcgaacc aagtccagac
    13741 tcatgatatg gtcataatgg gcgtgggtca agagaatagc acagatcggt ttgttgatct
    13801 tctcgattgt ctgacgaatg gcttcccaat gactaccagg atcgacgacg atgaggtgct
    13861 tttcgccttc tagataatag gtattttcat aggcaacagg attcacggtt ttatggattt
    13921 tcatactagc tccaatctca aagaatgtac taatactctt cgaaaatctc ttcaaactgc
    13981 gtcaacttta tctgcaacct caaagcagtg ctttgaacag cctgcggcta gctttctagt
    14041 ttgctctttg attttcattg agtataaatt aagtatagca cagttaggga gaataggtaa
    14101 ggatttaaaa tgaacttaaa aaccagcatg actagatgaa gacaggctgg ttatcaattt
    14161 atcaatattg gaaaggtgtc aattgccctt cataggttgc ataaactccg tcattagctt
    14221 gtttgataga cgtgatgttt agagtgctac cgtagttggc ttctcgtttg tcgctatatt
    14281 cactataagt tatcctactg ggcaggttct ggtcgttagc atagtattga acgactgttt
    14341 tttatagctt tgctggctga ataggaacag gcagcaaact cctaacatta ggagagcaaa
    14401 gatagaaata gcagtttttt tcataggtat tctccttata aactaaagga tagaagaaag
    14461 tatcttgagg atttttatac tcttcgaaaa tctcttcaaa ccgcgtcaac gtcgccttgc
    14521 cgtatatatg tgactgactt tgtcagtctt atctacaacc tcaaagcagt gctttgagca
    14581 acctgcggct agtttcctag tttgctcttt gattttcatt gagtattaat tccaaaatcc
    14641 agtcaaggta ccagtgtatg tgatacgagt tccaccgttt atctttcgta tcttcaatgg
    14701 aattggggaa atcagaaagt ctttgggtta caatatggtt tccgttcttc tatctctcct
    14761 tctatcacct aagtttaaaa tctaacttcg tagtatatta tgggccgata attcagaatt
    14821 atcaagcaat tttgaattat ttttttctta ttctgttcca atctagtttt catattctta
    14881 aaaaagtgat aaaatggtag gaagaattgg agagtagaga tgccgaaaga agtgaattta
    14941 acaggcgaag aagttgtcgc tttaaccaaa gaatatttaa cggaagagga tgttcatttt
    15001 gtccataagg ccttggtcta tgctgttgaa tgccacagtg gtcaatatcg caaatcaggc
    15061 gagccttata tcattcaccc tatccaagtg gcaggtattt tagctaagct aaagctggat
    15121 gctgtaacag tagcttgtgg attcttgcat gatgtggtgg aagatacaga tgcgaccttg
    15181 gacgatttgg aaagagagtt tggtcctgat gtgcgggtga ttgttgacgg agttaccaag
    15241 cttggcaagg tcgagtacaa atcaatcgag gagcaattag cggaaaatca tcgcaagatg
    15301 ctcatggcca tgtctgagga catccgcgtt attttggtca aactgtctga ccgcttgcac
    15361 aatatgcgga ccctgaaaca tcttcgaaaa gacaagcagg agcgtatttc caaagaaacc
    15421 atggaaatct atgccccact tgcccatcgt ttggggattt ccagtgtcaa atgggaatta
    15481 gaagacttgt ctttccgtta tctcaatcca acggagtttt acaagattac ccatatgatg
    15541 aaggaaaagc gcagggagcg tgaggccttg gtggatgagg tagtcacaaa attagaggag
    15601 tatacgacag aacgtcactt gaaagggaag atttatggtc gtcccaagca tatttactca
    15661 attttccgca aaatgcagga caagagaaaa cggtttgagg aaatctatga tctgattgct
    15721 attcgttgta ttttagatac ccaaagtgat gtttatgcca tgcttggtta cgtgcatgaa
    15781 ttttggaaac cgatgccagg tcgcttcaaa gactatattg ccaaccgcaa ggccaatggt
    15841 tatcagtcta tccatacgac tgtttatggg ccaaaagggc cgattgaatt ccagattcga
    15901 accaaggaaa tgcacgaggt ggctgagtac ggggttgcgg ctcactgggc ttataagaaa
    15961 ggtataaagg ggcaagttaa cagcaaggaa tcagctattg gaatgaactg gatcaaggag
    16021 atgatggagc tccaagacca ggctgatgat gctaaggaat ttgtggactc tgttaaggaa
    16081 aactatctgg ctgaggagat ttacgttttt accccagatg gagctgtccg ttcccttccc
    16141 aaagattcag gaccgattga ttttgcctac gaaatccata ccaaggtcgg tgaaaaagca
    16201 actggtgcca aggtcaatgg ccgcatggtt ccactgacaa ccaagttaaa gacaggggat
    16261 caggttgaaa ttatcgccaa cccgaactcc tttggaccta gccgtgactg gctcaatatg
    16321 gtcaagacta gcaaggcgcg caataagatt cgccagttct ttaaaaacca agataaggaa
    16381 ttgtctgtca acaagggtcg tgagatgctg atggctcagt tccaagaaaa tggctatgtg
    16441 gcaaataaat ttatggacaa gcgccacatg gatcaagttc tgcaaaagac cagttacaag
    16501 acagaagact ccctctttgc ggccattggt tttggggaaa tcggtgcgat taccgtcttt
    16561 aaccgtctga ctgaaaagga acgccgtgag gaagagcgtg ccaaggccaa ggctgaggca
    16621 gaggagcttg tcaaaggtgg cgaggtcaag gttgaaaata aagaaactct caaggtcaag
    16681 catgaggggg gagtggttat tgaaggtgct tctggtctcc tagtgcggat tgctaagtgt
    16741 tgtaaccccg tgcctggtga cgatattgtt ggctacatta ccaagggtcg tggtgtggct
    16801 attcaccgtg tggactgtat gaacctgcgt gcccaagaaa actacgagca acgtctcctt
    16861 gatgtggaat gggaagacca gtactctagc tcaaataagg agtatatggc ccatatcgat
    16921 atctacggtc tcaaccgtac aggactgttg aacgatgtac tgcaagttct ttcaaataca
    16981 accaagaata tttcaacggt caatgcccaa ccaaccaagg atatgaagtt tgctaatatc
    17041 catgtgtcct tcggtattgc caacctctct acactgacca cggttgtcga taaaattaag
    17101 agtgtgccag aagtttactc tgtcaaacgg accaacggct agttgtccta gctcttacta
    17161 gaaaggctat tatgaaaatc attatccaac gggttaaaaa agcccaagtg agtatagaag
    17221 gccagattca gggaaaaatc aatcagggac ttttattgct ggttggtgtt ggaccagagg
    17281 accaagagga agatttggac tatgctgtga gaaaactggt caatatgcgg attttttcag
    17341 acgcagaagg caagatgaac ctgtctgtca aagatattga aggagaaatc ctctctattt
    17401 ctcagtttac cctctttgcg gatactaaga aaggcaatcg tccagccttt acaggggcag
    17461 ctaaacctga tatggcatca gacttctatg atgctttcaa tcaaaaatta gcgcaagaag
    17521 tgcccgttca gacaggtatc tttggagcag atatgcaggt tgagctggtt aataacggac
    17581 ctgttaccat tatcctagat actaaaaaga gataagaaag accaagccca gtcggcttgg
    17641 tctttctcat cgatcataaa atactccaaa aagaaatcgg ttcttgatat gcttggggga
    17701 agtctctttt caggctttgg cagatgcgat aggaagggat gagatgtcct aggatgagga
    17761 gagttccctg aaggaaaagt ggaatatcac ttaaagacac caaggagaga atcatcaggc
    17821 tatcccatag gagaatttgt aaagcaaaac gccagaatct cggtctaatc tgggaataga
    17881 gttgactaaa gtggtcacaa agttggtttg aaagataggt caatagcacg ggatgaaaga
    17941 aaatgagcca accactataa atcaaaatcc agtcccaagt aagcccccct tttaaatgtc
    18001 aaaaatacca gcatgattcc atcaatgaca aggagttgaa tggttttgat gaagatgatt
    18061 tttttcatgc taaaacctcc ttttccttag agacactccc ctacaggtat tttagaatgt
    18121 atattgctta gatattcctt attttattag ctttttaagg tattaaagta gttatataag
    18181 tttatgaagg gtatcctatc ctgcacggct aattttgagt tcgaaactga ggagtttata
    18241 actcaaaatt tcgattaaat cagcatttaa cgatagtatg tttgtcataa aatgataaat
    18301 ttttagattg tggaattttt ttcaacttaa ttcttgattt tttttctaaa ttgttatata
    18361 cttaatttac gggataacag aatcccgtca gaaaggggtg ataatatggg aaaagagaat
    18421 gttagaatgc gtttagcgtc tgaatccaga cagatattag ataagcttaa agatgatgtt
    18481 tacaataaat taggctatga agtaagctat tccagtattg ttagtcaagc tgttagagaa
    18541 tacgttccta aaaaagaacg tatagattgg ataaaattaa aagagacagc tatacctttt
    18601 tcatcgttaa aacagagcaa taattgggag taccagacat cacttatgtt agagaaagat
    18661 gtattaatct tactgtctga actacaaaat tttttcttag atgtcttcca agcgaaacgt
    18721 atacataggg cattttgtat acgtctatgt ttgagagcgc aatttttatt aagtaataat
    18781 gattcttaat actatcaata ttaatgcgga gtgtaatgct ccgcaaaaat aaaacctatt
    18841 acgggataaa aacactactt tatttaggat ggaaataaga acgtattttt tactaatatt
    18901 gtttagaaag gagtttcttt atgacaccag aagaacaaac tgctttggaa tacttttatg
    18961 aggaactcga gagttacggt gaagatgagc aaggagaggt ctttgatttg tatgataatt
    19021 aaatcatctc catagtttct gagaataatt gagaaactat actctaaatc ataggtttat
    19081 gtaaagctag atatacacaa aaggaggtac gaatgaagat gaaagctaga gcttcaccgt
    19141 tgaattgatt ttgtttctag aaaaaatcaa taattagaaa aatacgaggt aaaaaaatga
    19201 atagaaatgt actaaatttt ctgcgaacag aaagtgctga aagagttagt ctttatatag
    19261 acaaggctaa tagattggag ggcgatgtaa ctctactcgc acctagttct caagatttgg
    19321 aagatattaa aaatgctatg ttttccaatc ctaatctcga gctaaaagta gcgagactgg
    19381 atgtgatgaa gaaaatagca tatgcttcta caagaaatca ttatttaaca ggggctacga
    19441 tttttgggga tatttcgaaa ggaacataca attgtgatcc taaaagttat gtctaatata
    19501 agggaggtta atccctcccc ttgtttttga aaatcgaaag gaaaagtata aaaatgaaag
    19561 ttaatgaata tttctggaga acgagctgtc ttatactaaa aaagaagaaa tcgataaaat
    19621 agtatacgtg ttagagatgt gtttgtcgta aaagtctgga tagttttctc ttaggtagtc
    19681 agctgtcata taataaaaag tagaatggca agcagtgatg attggcataa gagatgaaaa
    19741 acgctgagaa ctaatgaagg ctaagagaac aaaaaataga aaatcaatgg tgagaacccc
    19801 taaatagtag aagcgaatct ttttattgat ttgaggataa atctcagcga attgatgttt
    19861 gagtcggacg accaagagaa atagcaggag tccttgagca aggaagaaaa ttaaaccaga
    19921 gagcaagagc cactcaaaag atgtctcgag tctagtgata aaaaatgcaa atagtagcaa
    19981 atcaataact gcaattgcta taaaatggat tctatagagt tttttcatga caagacctcc
    20041 ctcttttatc taacttcatt ctactctaaa agaatgggag ttacaactaa aatgataaaa
    20101 atagcagagg ggagattctc ttaagttggc tagtattctt tatttgagtt tccttctatt
    20161 atctaacttc ttcatcattc cagacaaata aagctccgat tgcattgagg atataaaaga
    20221 tgtatttacc gatattggcg aagtttcctt gaataccagc ttttgtcagc tgaacgaaat
    20281 tgtaaatcaa ccaaaagccc cactgtccct cattgccaat gcattcaaag cattggcaat
    20341 gagggacagt gcaaaggcaa tagttgttac gtaggcaagg agattcatct tgcccccata
    20401 tccgatatag ttggtcacaa aggcaaagag gaaggcgatg atggaaatga tgatggccgc
    20461 caattttacc tgtttttggc tcatttggtt gggtctgcct tcttgcgaag ctttccattt
    20521 ctttatagca aaggtataaa tgaggaaggt gacgggatag gtaatgatgg ccgccttatt
    20581 tccaaggata taatcaatag caccggacaa aatggtatta acaataccaa agtaattttc
    20641 ccatttgctt aatttccccg tgaaacgagt ggacaacatg gaaatcccaa cgttggttac
    20701 ggaaatcaat ccaaagggta caagagctgt ccatggtccc cagtctacaa atttatcgag
    20761 gcgtgagttg aggtaaccag atgcaatcgc aatccaacga ccaaagcaac cccgaagagg
    20821 tcaaactatt tagatgtagc aaaaattttt agtgattttt tcataggtta aactaccttt
    20881 ctttttttca aatattctcc catttttttt caaatattct accaccaaat gaaagtaaaa
    20941 taaaatgata gaaataaaac cctgaaaata aaactttcag ggttggtagg ggacttgaga
    21001 aattagttga ttttctcgac atagagttgt tttgcaatgt ccatattcac ttgtaaatcc
    21061 tcgtcgttac tgaggatagt gaaggtattg ctgaagccat caaactgctt aacttggagc
    21121 tggtcaccga tgtgaagtga gtgcttgtcc agataatgga gaatgtcaaa actatcgtgc
    21181 atccgagtca ggcggtaggc gccagcttcc ttgatatcag ctagtgggag gttattgatt
    21241 tcaacgagga gttctccctt ggcaggaata gttcctccgt gggggcaggt tttagggaaa
    21301 cctagcagtt tatctagtct ttccacgaac aggtcagaga cagtgtgttc caagacctca
    21361 gcttcctcgt gaatctggtc acttgtatag tctaaatgat gaactagaaa aacttcaatc
    21421 aagcggtgct tacgatagag ctcagagacc agtttgagac cgaggtcagt cagtagatag
    21481 ccacattcct tgtcctttag gatgagattt tcacttttca ttcgtttgat catttcagtt
    21541 acggcagggg gagagacttg catgcgagcc gcaatttcct tgttggtaat cttatgcagg
    21601 tctatgccaa tttcataaat acattttaga tagtcttctt tgtttggggt cattcgtttc
    21661 ctcttgtcta atatctttat ctagtatatc aaaaaaagct agatttctct agctgtgact
    21721 ttttatgtta tacttattgc aagagaaaaa acgaggagat ggatatgacg aaaatagctc
    21781 ttctttcaga tattcatgga aataccaccg ccttggaggc tgttttggca gatgctcggc
    21841 agctaggagt ggatgaatac tggcttttgg gagatattct catgccaggg acagggcgta
    21901 gaaggatttt ggacttgttg gatcaactac cgattacggc tagagttttg ggaaactggg
    21961 aagacagtct ttggcatggt gtccgtaagg aattggatag tactcgccct agtcaacgct
    22021 atctcttgcg ccagtgccag tatgttttag aggaaatttc cctagaagaa attgaagtgc
    22081 tccacaatca acctcttcaa attcatcgtc agtttgggga tttgacagtg ggaattagcc
    22141 atcatctgcc tgataagaac tgggggcgag agttgattca tactggcaaa caagaggaat
    22201 ttgaccgctt ggtgactcat cctccctgtg atattgctgt ttatggacac attcaccagc
    22261 agttgcttcg ttacgggact ggtgggcaat tgattgtcaa tccgggttcg attggccaac
    22321 ctttcttttt ggacgctcag ctacggaagg acttgcgggc ccagtatatg attttggagt
    22381 ttgatgacaa gggcctggta gatatggact tccgacgggt agactacgat gtggcagcgg
    22441 aattgcagct ggctaaagac ctgagacttc cctattttga ggtttactat gaaagtctgg
    22501 tcaatgggat ccaccatact catcatcagg aatttttgag agaattggct cagaaagagg
    22561 gttgcgatcg ggagttagac gactggttga aaagtggtaa cgattgacat tacaactaaa
    22621 aagggtataa taatagaaaa agaagagtag aggcagggta gcctcgtaaa aaggagaaga
    22681 ggatgcaaat tccaagtaga tttaccattg cgactcatat gctgataatc attgccctcg
    22741 aggggaagaa aagcaaggtg accagtgatt ttctggctgc tagtgtcggg gtcaatcctg
    22801 tcattatcag aaagatcttg tcccagttga agaaggcaga gctgatttca gtagcgcgtg
    22861 gaacgggcgg aacagatatt gtcaaggacc ttaaggatat tagtctttta gatgtttatc
    22921 aggcggtcga atgtcttggt aagacaggtc aactcttcag tttccatgac aatccgaatc
    22981 caaattgccc tgtaggagct catattcatg atgttttgga tcaaaaattg gagagaattc
    23041 agttgactat ggaggcagaa cttggtcaaa ccagtctaga aaaagtcgtg gccgatgcag
    23101 agagtcagat gaaggattaa gagggataaa tgccctcttt tttctttgga taattatgat
    23161 aaaatgtagc tattaaagga gtaagaaatg tatctcgtta taggaattgt attagccttt
    23221 atagtgtcat tttggaagga taatagaagt ttgtggaatc cagtattatt tttattatcc
    23281 ctcatttcaa gttattttta tctatcctac cttttttata aaaatggata cgagaatgtt
    23341 cagttagctt tttatgtatt tgcctttgtc ttacttcctt ttttgctttt tctaagtggc
    23401 atctttttaa tctataatgg ggtcattttg ttgaaacgag agggacgttc caagcccaat
    23461 tatctttcaa tgctatttga tttttattga ctattagatt ctatttaaaa agacttagaa
    23521 tgcacatgaa agtatgtatt ctaggtcttt tgttttgtat acatttaatt ttcaagagta
    23581 ttatctattt ttccatgcct ggtaacgagt atcaatcaat aactgggtaa ggcgacccaa
    23641 ggtttctctt tcttctggag tgagggattg agcttggaca aagagatgat gaatgtattc
    23701 aagcgccttt aaggaagcca agtcattgat agagctaata ccagcatcaa gaatagtgcc
    23761 aaagaagagg tcgaagtaga gctgaagttc ttcgtcaggg actgtggcca cccattcttt
    23821 aaaggttgtg tctacttgct ggctatcact gttggtctta tccagttgaa cgaagtgctt
    23881 gtcctcaatc tgccaactaa aggtatcgtg ctgggcgatg ccacccaggg cagtactctg
    23941 aacgatgatt tggtgagcag gaatttccag catcataccg ataatggaac cttgtggaat
    24001 gaatatcttg cttctatcca ttatcctttg ataacccgca gtctgtgtca attcttgatg
    24061 gagaccaggt gcatcaaatg tataaactgc tgtgatctga ttttgcaaac tttgctcaat
    24121 ttggctagca gcatagatag cgagatttcc tcccttggaa tgcccagcca gaataacctt
    24181 ttgcttagga tgatgggcaa aaaagttctt taaatagcga agggcgtgct tttgagcagg
    24241 aatttccttc atataggtca ggtggaaatc ttccttccag ccaatgatac tgtcatctgt
    24301 cccacgaaag acaatcagat aggtatcgag gctgacacga taagtcatag ccgcaaattg
    24361 cttttgcagt tcagggtcga tgtcgttgat aaaatgggag agtttgcaat ttttgaagcg
    24421 cttgtgttga gccaattcat ctaataattg aaggcgattt ttgctagtaa gcatggtggg
    24481 ctctcttgga acctgaggtg ctagatctaa aagacgttga ggaagtgtgg agaccagatt
    24541 atcaaaggag aggtaggtga tttctattaa ggttagaatg tctaactcat tcaagggaag
    24601 gtcgtaataa gaatcatatg cgacatcttt cagatagtca aaaatattgg ccataagagc
    24661 tcctttcttt ttatttatct tagcaaattt ccctcaaatt agctagtagc attgcctgtt
    24721 tgtactggct aaaaacaggc tatttcaaat tcagtttcag accatctagc atggaaaaat
    24781 ctgttataat agtagaaaag gagaagcgca tgcacaagat tttattagtg gaagatgatc
    24841 aggtcattcg tcaacaggtc gggaaaatgc tctctgaatg gggatttgaa gtggtcctgg
    24901 tagaagactt tatggaagtt ttgagtctat ttgttcagtc ggaacctcat ctggtcctca
    24961 tggatattgg tttgcccttg tttaatggtt atcactggtg tcaggaaatc cgcaagattt
    25021 ccaaggtacc tatcatgttt ctttcttcga gagaccaggc tatggatatt gtcatggcaa
    25081 tcaatatggg ggcggatgac tttgtgacca agccttttga ccagcagatt cttttagcta
    25141 aggttcaggg cttgttgcgt cgttcctatg agtttgggcg tgatgagagt ttgctggaat
    25201 atgctggtgt tatcctcaat accaaatcca tggatttaca ttatcaaggg caagtcttga
    25261 atttgaccaa gaatgaattc cagattttac gcgtgttatt tgagcatgca ggcaacatcg
    25321 tagcacgtga cgacctgatg cgggaacttt ggaacagtga ctttttcatt gatgataata
    25381 ccctctctgt caatgtggct cgtttgcgta aaaagttgga ggagcaggga ttggtaggat
    25441 ttatcgagac caagaaagga atagggtacg gattgaagca tgcttgattg gaaacaattt
    25501 tttctagcct atctgcgctc ccgtagtcgt ctttttatct atctgctttc tttggcattt
    25561 cttgtcttac tctttcagtt tttatttgcc agtctaggaa tttacttcct ctactttttc
    25621 ttcttgtgtt gctttgtaac catcttattt ttcacttggg acatattggt ggaaacgcag
    25681 gtctatcgcc aggaacttct ctatggagag agggaagcca agtctccttt ggaaatagct
    25741 ttagcagaaa aattagaagc gcgtgagatg gaactctatc agcagaggtc aaaagcagaa
    25801 agaaaactga cggatttgct ggattactat accttgtggg tccatcagat aaagaccccc
    25861 attgcagcca gtcaactctt agttgcagaa gtggtcgacc gccaactgaa gcagcagcta
    25921 gaacaggaaa ttttcaaaat cgactcctat accaacctag ttttacagta cctgcgttta
    25981 gaaagtttcc atgatgattt ggtcttaaag caggttcaaa ttgaggactt ggtcaaggaa
    26041 ataattcgta aatatgctct tttctttatt caaaaaggct taaatgtcaa tctacatgac
    26101 cttgataaag aaatcatgac ggataaaaag tggctgctag tggttattga gcaaatcatc
    26161 tcaaacagtc tcaagtacac caaggaaggt ggtctggaga tttatatgga tgaccaagag
    26221 ctttgtatca aagatacggg aatcgggata aaaaacagtg atgtcctccg agtatttgaa
    26281 cgtggctttt caggatacaa tggccgtttg acccagcagt cctctggact tgtcctttat
    26341 ctatctaaga aaatttctga agaactgggg caccagattc gtatcgagtc tgaggtcgga
    26401 aaaggaacga cagtgcggat tcagtttgct caagtgaact tagtccttga gtaaaaatag
    26461 atgagaaaaa gcctccagat tggaggcttt tatgctagac tcttatttct caacgcgtga
    26521 tttgttggcg atatcagcta ggatagcttg aacaaaatta tcaactgaga cagtttgtgt
    26581 ttctttttgg ccgtagcgac gaacgttgac tgtttcgtct tccatttctt tgtctccaac
    26641 aattaattgg taaggaatct tgctggtttg tgaagcacgg atcttgaact gcattttttc
    26701 attgcgctca tctacgtctg cacggacacc gcggtcacgg agtttcttgg ctacttccca
    26761 agcgtagtcc acgtgttttt cgttagatac tgggataagg gttacttggt gtggtgccag
    26821 ccatgttggg aaggcaccct tgtagttctc aatcaagata gctgtgaagc gttccatagt
    26881 tgagataacc ccacggtgga tcatgactgg acggtgatct tcgccatcag ctccgatgta
    26941 tttgaggtcg aagcgttctg gcaacaagaa atcaagttgg atagtagaaa gggtttcttc
    27001 ttttccaagg gcagttttaa tctggatatc caattttggt ccgtagaagg ccgcttcacc
    27061 ttcggcttca aagtagtcca cgcccatttc atcaagagct gcacgaagca tggtttgggc
    27121 attttcccac atctcatcgt tatcaaagta cttatgagta tcttgagggt cacgaagaga
    27181 gaggcggaag cggtagtcag tcaagttgaa gtcttcataa acatcgataa tcaactgaag
    27241 ggcacgttgg aattcttctt ggatttgttc tggagtaacg aataggtgac cgtcgttgag
    27301 tgacatttca cgtacacgtt gaaggccagt gagggcacca gatttttcgt aacggtgcat
    27361 cataccgatt tcagcgatac ggattggcaa ttcacggtaa gagtgaacat ggtgtttgaa
    27421 aacttggatg tggtgcggac agttcattgg acgaaggaca aattcttccc cgtcacccat
    27481 gtccatggtt gggaacatgt cttcttggta atgatcccag tggccagaag tcttgtaaag
    27541 ctcaacagaa gcaagtggtg gagtgtagac gtgttggtag ccagaagcca actctttgtt
    27601 tacgatgtag cgttccaatt cacgacggat agtcgcacca tttggcaacc agaatggcaa
    27661 accttgtccc acttcttgtg aaatcataaa gaggtcaagc tctttaccaa gtttacggtg
    27721 gtcacgttcc ttagcttctt cacgcatttg aaggtagttt ttcaagtctt tcttttcaaa
    27781 ccaagctgta ccgtagatac gttgcatcat agcgttgtcg ctgtttccac gccagtacgc
    27841 accagctaca tggagaaggt ggaagatttg gatacgacct gttgatggaa cgtgaggtcc
    27901 acggcagagg tctacatatt caccctgacg atagatagtc aaaccgcctt cgtcttctga
    27961 gtgttcttca atcaattcca acttgtaagg gtcatttttg aagatttcac gtgcctcgtc
    28021 tttagtcact tcttcacgaa tagatgggaa gttttctttg acgatttttt gcatttcttc
    28081 ttcgatacga ggaaggtctt cgttagagat ttgaccagct gtgttgtcag tatcgtagta
    28141 gaaaccatct tcgatggctg gaccaactcc caagtgaatg tctgggaaaa gacgacgagc
    28201 tgcttgggcg aacaagtgag ctgctgagtg gcgcaagatt ggaagggcat cttcgtgatc
    28261 aggtgtcaca atttcgatgc ttccatcttc agtgatagcg cgagtagtgt cgatgagttt
    28321 gccgttgaat ttaccagcca aggctttttt agctagggaa ttgctgatag attgggcaat
    28381 ttcaaaagtt gttacgccag attcgaattc acgaacagcg ccatctggga aagtaatgtt
    28441 aatcatgatg ttctcctttt ttattatttc atagtttcta agcattgatt ttttatcatc
    28501 agactacttc caagtcctaa cgttcaattg cttttcttta tcagagagga agttttccat
    28561 ttccgtcaga atgtctatat ccaaacgttg agaaagttct aatagccacc agatattttc
    28621 tgaaagtttt tgttccagtg tgtagggtgt ttcatcatag tagcgtcctt gctttgtcat
    28681 caccagtcgt tggaaatttc caatatcatt agataaagcc aaggggtctt cttctaccgt
    28741 ccacttggaa tcatgatgct taacttccag ttcgtgataa gcttgtcgga ttgcccaact
    28801 gcgctccact aattcttgca actccataat tagtatccta ataaaaaaat gcgacatcct
    28861 cgaaaggacg tcgcaacgtg gttccacctt catttatgta cctcaaaaga gagggacacc
    28921 tctgattggc tctaacgtgg ccaccgtttt atgttttcat aaaaaactca agagtagtat
    28981 cagtttagac ttcctatgcg tttccagcaa ccacgcactc tctagtagaa agggactaag
    29041 tgacttgtct ctatggatta ttatagcatg attgtgagat ttttcaagga ttttgtgaaa
    29101 gttttttgtt tttcattttt tgtagaatat gcttgatgct aataccagaa tccatgccca
    29161 ccagagcaac tgtttcatag attagcaagt aaattagtat aaactcacca aaggttatga
    29221 tagtaaagta aaagagcagt ccgttaccaa ctaaccatca aagtgagaaa cggaaacggt
    29281 agctatagag taacgataca atcaagatta ccagaggtgt aaagaagaga agattgttta
    29341 tatagagttc cttgagtgta agggggtcag aaacaactag taagaacaac tcataaagtg
    29401 gccaataaaa gaataatatg accagatagt aggggagatg ggaatagaat ctacgcatga
    29461 taatcacctc gttttaaaaa aacagacaac ttagatctct tgctatgatt attatagcat
    29521 gtttaaaaca agaaagtaaa tttgttggca aagaagattt ttttttcact agaatcatgg
    29581 ttagttttct tggtagaaat attttgataa taattaagca aaactattga cattgattat
    29641 taagagtgtc acaattgttg taactaaaat aattacaata agagaggtat aaaaaatgaa
    29701 actagcagtt attgcagcaa atggacaagc ggggaaagca attgttgaag aagtagtcaa
    29761 acgaggacat gaagtaacgg ctattgttcg ttctgaaaac aaaagtcaat ctgagtctat
    29821 tattaaaaaa gatttatttg agttgacaaa agatgatctt actggatttg atgctgttat
    29881 ttcagcgttt ggtgcttata caccagatac gctaccgctc cacagcaaat caatcgaact
    29941 atttaatcag cttcttgctg gaacacagac acgttttcta gttgtagggg gagcaggaag
    30001 tctttatata gatgaaacaa aaacgacacg acttttagat acgtctgatt ttcctgaaga
    30061 atttaagtca ctagcaaaag ctcaagcgga tgaattggat cttcttcgta caaaaaataa
    30121 tctcaactgg acttttgtca gtcctgctgt agattttatt cccgatggtg aaaaaacagg
    30181 aaactacatt ctagcaggag aaatttttac tactaatgaa aaaggaataa gccagattag
    30241 ttatgcagat tatgctattg gattggtaga tgaacttgaa aaaggtcatc atataaaaga
    30301 acgtatctct ttacttgaaa aataataact atgagagtat taatgtttga cagaaaattt
    30361 aaatcttggt aaaataggga ttgtcgtaaa gacaaataac ttcttcttgg ttacaggcat
    30421 gccaacctgt cactcggatg aagccaaata aaaaggagaa acatcatggc aatctcaaaa
    30481 gagaaaaaaa atgaaatcat tgcacaatat gcacgtcacg aaggtgatac aggttcagta
    30541 gaggttcaag ttgctgtcct tacttgggaa atcaaccacc ttaacgaaca catcaaacaa
    30601 cacaaaaaag accacgctac ttaccgtgga ttgatgaaaa aaatcggtcg ccgtcgtaac
    30661 ttgcttgcat acttgcgtaa aaacgacgtt aaccgttacc gtgagttgat caactctcta
    30721 ggacttcgtc gctaattcaa gatacaaagg ccgtcaaaaa cacaaagcaa aaataggaaa
    30781 attgacgaag aaacttcagt ttctaggaga ttttatcttt tttgccaagt gcttaggccg
    30841 tgttcaattg agcatatctt gataataaag ctactctaaa ttgggtagct ttgttgcgtt
    30901 gtcaccttac ctcgctatac tcaagtataa tcttcggtta cggttcctag cactgtaagg
    30961 taaaataaac tagcttttct cccttcgggg agattttttt gtttcactga aagtttcgta
    31021 cgatcttcac ctcgtcccct agtctataaa cgatttatct agcaagaatc atgatgctaa
    31081 gggcgtcaaa aatccgtatg aaaataggga aatgacacag tgttcgatga gcacaaggag
    31141 tttcatcttt ttcactagga ttttagcccg ggctaaaatc agctctctga cttcagaggg
    31201 cttttttatt gaggttttat cggtaacaat tttggagact acaaaaacct caaatggtat
    31261 cagctaatta caccataaag gtgcgcagtt actcggcttt tcaagccgag tagctgtatg
    31321 caagccccct agaagagccc actctttaca aagtaaagta tagtatgtta tactttacat
    31381 ggaagtagtc actgaattcc agttagaaat tactttgtaa ctacgttttg aggaggagaa
    31441 aaatgctttc ctacgttcga cattacccac tagcgatagc taaattaatg tgtctgtgct
    31501 ctcctaaaat ctgctgattt attactgact aatacaggag gtttttttta tgggacagac
    31561 aatcatatct gctattggtg tttatatttc caccagtatc gattatttaa ttattttaat
    31621 tattttattt gcacagctat cacagaataa acagaaatgg catatttatg cggggcaata
    31681 tctaggcaca ggcttacttg taggggcgag tttagttgct gcttatgtcg ttaatttcgt
    31741 gcctgaagaa tggatggttg gattgcttgg tttaatccct atctatttag ggattcgctt
    31801 tgcaattgtt ggagaagatg cggaagaaga agaggaagaa attattgaaa gattagaaca
    31861 aagcaaggca aatcaactgt tttggacagt tacattgctg acaattgcgt ctggcggaga
    31921 taatttaggt atctatatac cttattttgc ttcgttagat tggtcacaga ccctcgtggc
    31981 cttgcttgtg tttgtaatcg gcataattat cttttgcgag attagtcggg tgttatcctc
    32041 tattccgtta atattcgaga caattgaaaa atacgagcga atcattgtgc ccttagtatt
    32101 cattctactt ggactataca tcatgtatga aaatggcacg atagagactt ttctgatcgt
    32161 gtagattttt ttgtttcact aggattttag cccgagctca aatcagctct ctgattttca
    32221 gggggctttt tcattgagta taaatggaca atcttaaagt tactctattg tagagtggct
    32281 tttgatttga ttaggagatt cttataaata tagtaaaatg aaataagaat aggacaaatc
    32341 gatcaggaca gtcaaatcga tttctaaaaa tgttttagaa gtagaggtgt actattctag
    32401 ttccaatcta ctatataaat gaaaacctta gctgtttggc caaggttcat ttcttctatg
    32461 caagttcttc tcttttctta tctgggttcc agatgaagct tgcgataaag ctaaagatga
    32521 tggttaggat agcgaggata atagcaagga tgagggcagg gatgcggata aaccaccaga
    32581 gtggatttgg ttttttatca ttgtgccatt gtttcgtttc ttcgtccaga cgttggaatt
    32641 ctgtttgaat acgattggcg actgtttcaa tgccttcatc attcattttc ttgatatctg
    32701 agatatcgat tggatttcca aagttcatat cgacacgttc acggctaatc aagcccttca
    32761 aagtcatggg accggtgtag gtaaccggca tgatacggac cttggccatt ttggcaatca
    32821 gtgctgcgcc ccccttgaca tcgtttgagt ggcggctacc acttggaaac atgatgagag
    32881 agcggtcact ttttttgaga acgttgatag gatatttgat ggctgaggcg ctgggatttt
    32941 cacggtcgat gggaaaggcg ccacacatac gaatccacca accaaagata cggttggtaa
    33001 agagttcttt ttttgccata aagatgaact gttttggctt ggtcgcaaag gccatataaa
    33061 caggatccca ccaggtacgg tgaggcgcaa ctaaaatata attttcatct tgattaggaa
    33121 ttttatcagt attatgatag tgagcattgc cattgatgga ccataagagc aatacaacta
    33181 atccacgcaa ataagtataa aacatgcgat ctccttcaat tgttttcttg ttattattat
    33241 accttatcaa aggagggctg gcaaactttt cccttgacta gatgcatatt tgggatgaaa
    33301 ttagaattct gttaaaaaaa atgatataat agaatttatg gataaaaata agattatggg
    33361 attaacccaa agagaagtca aggaaagaca ggctgagggt ttggtcaatg actttaccgc
    33421 atcagccagt accagcactt ggcaaatcgt taaacgaaat gtctttaccc tttttaacgc
    33481 tttgaacttt gccattgctt tggcccttgc ctttgtgcag gcttggagca atctggtctt
    33541 ctttgctgtt atctgcttta acgctttttc tgggattgtg accgagctac gagccaaaca
    33601 catggtggac aagctcaatc tcatgaccaa ggaaaaggtc aaaaccatcc gtgatggtca
    33661 ggaagttgct cttaatcctg aagaattagt gctaggagat gtcattcgtt tgtctgcagg
    33721 agagcagatt cctagtgatg ccttggtttt ggaaggcttt gcggaagtca atgaagccat
    33781 gttaacggga gaaagtgatt tggtgcaaaa ggaagttgac ggcttacttt tgtcaggaag
    33841 tttcctagcc agtgggtcag ttttatctca agttcaccat gtcggtgcag acaactatgc
    33901 tgccaaactc atgcttgagg ctaagaccgt taaacccatc aactcccgta tcatgaaatc
    33961 gctggacaag ttggctggtt ttactgggaa gattatcatt ccctttggtc tggctctctt
    34021 gctggaagcc ttgcttttaa aaggcctgcc tctcaagtca tctgttgtaa actcgtcgac
    34081 agctcttttg ggaatgttgc ctaagggaat tgcccttttg accattactt cgctcttgac
    34141 tgcagtgatt aagctaggtt tgaaaaaggt cttggtgcag gagatgtact ctgttgagac
    34201 cttggcgcgc gtggatatgc tctgtctgga caagacgggt accatcaccc aaggaaagat
    34261 gcaggtggag gctgttcttc cactgacgga aacttatggt gaagaggctg ttgccagcat
    34321 cctgaccagc tatatggccc atagtgagga taaaaatcca acagctcaag ccattcgcca
    34381 gcgttttgtg ggagatgttg cttatcctat gatttccaat cttcccttct cgagcgaccg
    34441 caagtggggg gctatggagt tagaaggttt gggaatagtt ttcttagggg cacctgagat
    34501 gttgctggat tctgaagtcc cagaagccag ggaggccttg gagagaggat cacgtgtctt
    34561 ggtcttagct ctcagtcagg agaaattaga ccatcacaaa ccacagaaac catctgatat
    34621 tcaggctcta gccttgctgg aaatcttgga ccccattcga gagggagcag cagagacgct
    34681 ggactatctc cgttctcagg aggtgggact caagattatc tctggtgaca atccagttac
    34741 ggtgtccagc attgcccaga aggctggttt tgcggactat cacaactatg tagattgctc
    34801 aaaaatcacc gatgaggaat tgatggccat ggcggaggag acagcgattt tcggacgtgt
    34861 ttcccctcat caaaagaaac tcatcatcca aacgttgaaa aaagcgggtc atacaacggc
    34921 tatgacaggg gacggggtta atgatatctt ggcccttcgt gaggcggatt gttctatcgt
    34981 gatggcggag ggggatccag caacccgtca gattgccaat ctggttctct taaactcaga
    35041 ctttaatgat gttcctgaga ttctcttcga gggtcgtcgc gtggtcaata acattgccca
    35101 catcgccccg attttcttga taaagaccat ctattccttc ctgttagcag tcatctgtat
    35161 tgccagtgct ttactaggtc ggtcagagtg gattttgatt ttccccttca ttccgatcca
    35221 gattaccatg attgaccagt ttgtggaagg tttcccacca ttcgttttga cttttgagcg
    35281 aaatatcaaa cctgtcgagc caaacttcct cagaagatcc atgcttcgtg ccctaccaag
    35341 tgccctcatg gtcgtgttta gcgttctttt tgtgaaaatc tttggaacga gtcaaggttg
    35401 gtctgagtta gaaatctcaa ctctcctcta ttatctcttg gggtcaattg gtttcttatc
    35461 cgtatttaga gcctgcatgc cattcactct atggcgagtc ctattgattg tctggtcagt
    35521 aggaggcttc ctagccacag ctctcttccc aagaattcaa aaactgcttg aaattgcaac
    35581 cttaacagga caaacattac ctgtttatgg tgtcatgatg ttggtcttta ccgtgatttt
    35641 catcctgacc agtcgctatc aagccagaaa ataaagaaag gctgcaatct gtggattgca
    35701 gtttttttag gtacaagatt gccagccgaa atgtggtata ataagaggta atagagtttt
    35761 ggaaagtgag agaagatgat ttcaaagaga ttagaattgg tagcttcctt tgtgtcacag
    35821 ggggctattt tactagatgt gggaagtgac catgcttatc tgcctatcga gttggttgag
    35881 agaggccaaa tcaaaagcgc tattgcaggt gaggtggtgg aaggtcccta tcagtctgcg
    35941 gttaaaaatg ttgaggctca cggcctaaag gagaaaatcc aagtccgttt agccaatggc
    36001 ttggcagctt ttgaagagac tgaccaagtg tctgtcatta ccattgctgg catgggtggt
    36061 cgtttgattg ctaggatttt agaagaaggt ttggggaagt tagctaatgt agagcgtttg
    36121 atcctccagc ccaataatcg tgaagacgac ttgcgtatct ggctacagga tcatggattc
    36181 cagattgtag cagaaagaat cttagaagaa gctggaaagt tttatgagat tttggtggtg
    36241 gaagcaggac aaatgaagct atcagccagt gatgttcgct ttggtccctt cttgtccaaa
    36301 gaagtcagtc cagtatttgt ccaaaaatgg caaaaagaag ctgagaagct agagttcgcc
    36361 ctcggacaaa tcccagaaaa aaatctggaa gaacgtcaag ttctagtaga taagattcaa
    36421 gctatcaagg aggtgctcca tgttagcaag tgaagtgatc caagcttatg aagccttttg
    36481 ccctcaggaa ttttctatgg agggagacag ctgtggtctg caaattggca ctttagacaa
    36541 gggtatccaa agggtcatgg ttgccctcga tattcgtgaa gagacggtgg ctgaagccat
    36601 tgaaaagggt gtagacttga ttatcgtcaa gcacgcgcct atctttcgtc ctatcaagga
    36661 cttgcttgcc agccgtccgc aaaatcagat ttacattgac ctgattaagc atgacatcgc
    36721 agtttatgtc agccatacca atattgatat cgttgaaaat gggctcaatg actggttttg
    36781 tcagatgcta ggaatcgagg agacgactta tctgcaggaa acaggtccag aacgtggaat
    36841 tggacgtatt gggaatattc agcctcagac attttgggaa ttggcccaac aggtcaagca
    36901 agtctttgac ctagatagcc ttcgaatggt gcattatcaa gagaatgatt tgcagaagcc
    36961 tatttcaaga gtagcaattt gtggtggaag cgggcagtct ttctataagg atgctttggc
    37021 aaagggggca gatgtctata tcactggtga tatctactac catactgctc aggatatgct
    37081 gtctgatggc ttgttagcat tggatccagg tcactatatc gaagtgcttt ttgtggaaaa
    37141 aatcgcagca ctccttactc aatggaaaga gaaaaaaggc tgggaactag agattttacc
    37201 tagtcaagca tcgaccaatc ctttccgtca tatctagtta gaaagtgaag acaatgaaaa
    37261 aagttgccat tattggagca ggaattgtgg gagcaacagc tgcctactac ctctcgagag
    37321 aaagtgacct agaggtgacc gtttttgacc atgagcaagg tcaagccacc aaggccgcag
    37381 caggaattat cagtccttgg ttttccaaac gccgtaataa agcctggtac aagatggcgc
    37441 gcttgggggc tgacttttat gtggatttat tagctgattt agagaaatca ggacaaaaaa
    37501 tcgactttta ccagcgttcg ggagtctttc tcttgaaaaa ggatgaatcc aagttggaag
    37561 aactttatca actggccctc cagcgcagag aagaatctcc cttgataggg caattagcca
    37621 ttctggacca agcttcagct aatgaattat tccctggttt gcagggattt gaccgcctgc
    37681 tctatgcttc tggtggagcg agagtagatg gccaactctt ggtaactcgt ctgctagaag
    37741 ccagtcatgt caagctggtc aaagaaaaag tgactctgac actcttatca tcaggctacc
    37801 agattggcga agaggtgttt gatcaggtta ttttggcaac gggagcttgg ttgggggaca
    37861 tgttagagcc tttaggttat gaagtggatg tccgtcctca aaaaggacaa ctacgagatt
    37921 atcagcttgc ccaagacatg gaagattacc ctgttgtcat gccagaaggg gagtgggatt
    37981 tgattccctt tgcaggtggg aaattatcct tgggcgctac ccatgaaaat gacatgggat
    38041 ttgatttgac ggtagatgaa cccttgctcc aacaaatgga ggaggcggcc ttgcctcatt
    38101 acccagtttt agctagagcg acttcaaggg ctgagcgtgt gggaatccgt gcctatacca
    38161 gtgatttctc tcccttcttt gggcaggtgc cagaattggc aggtgtctat gtagccagtg
    38221 gactaggttc atcaggcctc acaactggtc ctatcattgg ttaccatcta gcccaactga
    38281 tccaagacaa ggagttgacc ttggaccctc taaattaccc aattgaaaac tatgtcaaac
    38341 gagtaaaaag cgaataatac tcaatgaaaa tcaaagaaca aactaggaaa ctagccgcgg
    38401 gttactcaaa gcactgcttt gaggttgtgt atagaactga cgaagtcagc tcaaaacact
    38461 gttttgaggt tgtagataga actgacgaag tcagtaacca tacccatggc aaggcgacgt
    38521 tgacgtggtt tgaattggat tttcgaagag tataagcatt ttactgaaat tttatcaggt
    38581 agtttaggat ggcaaatgac attccctgtc aaaaatggta aaataagaaa aaataatctg
    38641 agaatcgagg aaaaaagatg caagaaaaga ttttggtaac tggtggtgcc ggttttattg
    38701 gaacccacac tgttattgaa ttgatccaag caggccatca agttgttgtg gtggataatc
    38761 ttgtcaatag caatcgtaag agtttagaag ttgttgaaag aatcacagga gttgagattc
    38821 ctttctatga ggcagatatt cgtgacacag ttaccctcag agatattttc aagcaggaag
    38881 aaccgactgg tgtcattcac tttgctggtt tgaaggctgt tggcgaatca acacgtatcc
    38941 ctcttgccta ctatgacaac aatatcgctg gaactgtcag ccttttgaaa gccatggaag
    39001 aaaacaactg taaaaacatc atcttcagtt cttctgcgac agtttacggg gatccgcaca
    39061 cagtgcccat cttggaagat ttcccacttt cagtgaccaa cccatacggt cgtaccaagc
    39121 tcatgctaga ggaaattttg accgatattt acaaagcaga ctcagaatgg aatgttgtct
    39181 tgcttcgtta ctttaaccca atcggagccc atgagagtgg tgatttggga gaaaatccaa
    39241 acggtattcc aaacaatctc ttgccatatg tgactcaagt agccgttgga aaattagagc
    39301 aagtgcaagt gtttggagac gattacgata cggaagatgg aacaggtgtt cgtgactata
    39361 tccacgttgt cgatttggct aagggtcacg ttgcagcttt gaaaaaaatc caaaaaggtt
    39421 caggactaaa cgtttataac cttggaactg gtaaaggtta ctcagttctt gaaattatcc
    39481 aaaacatgga aaaagcggtg ggacgtccta ttccttaccg catcgtagaa cgtcgcccag
    39541 gtgatatcgc tgcctgctac tcagacccag caaaagctaa agcagaactc ggttgggaag
    39601 cagaactcga catcacccaa atgtgtgaag acgcatggcg ttggcaaagc aagcatccaa
    39661 atggatttga agactaagat gatgatttca atcatcgtcc cttgtttaaa cgaagaggaa
    39721 gtacttcctc ttttttatca ggctctggaa gctttacttc cagatttgga aacagaaatc
    39781 gagtatgtct ttgtcgatga tggatcaagt gatgggacct tggaactctt aaaggcctat
    39841 cgggagcaaa atccggcagt ccattatatt tctttctctc gaaattttgg caaagaagca
    39901 gccctttatg caggcttgca atatgcgaca ggagatttgg tggtggtgat ggatgcagac
    39961 ctccaagatc ctcctagtat gttgtttgag atgaaaaatg tactagacaa aaatgtagac
    40021 ttggactgcg ttgggacacg gagaactagt cgggagggag aacccttctt tcgcagtttc
    40081 tgtgctgttc tcttttatcg cctcatgcaa aaaatcagcc cagtagctct gccgtcgggt
    40141 gtccgtgact ttcgtatgat gagaaggtct gtggtcgatg ccattttaag cttgactgag
    40201 tccaatcgtt tttctaaggg actctttgcc tgggtcggct ttaaaaccca ctatctggac
    40261 tatccaaatg tcgaaaggca ggctggcaag accagttgga gttttaggca actctttttt
    40321 tactccattg aagggattgt taatttttca gatttccctt tgactatagc ctttgtagct
    40381 ggtctcctat cttgttttct ttctctgctg atgacctttt ttgttgtggt tcggaccctc
    40441 attttgggca atccgacatc tggttggacc tctctgatgg ctgttattct ctttcttgga
    40501 ggcattcaac tcttgaccat tgggattctc ggtaagtata tcagtaagat ttatttagag
    40561 actaaaaaaa gaccacttta tcttatcaaa gaaaaaagtg accttcctga ttttacagaa
    40621 aaaataaagt gaaaagacta taattttaca tggaaatgtg ctaaactaga gggagtggat
    40681 tatcgccatt gatttaggct tcctggtttc caatcagggc gcgagttggg caatttttaa
    40741 cagcctctaa gacatcctga ctaggagaaa tttctttttc cagttggtca gggtcatcgt
    40801 aaaaacgcac gattccatta tcgtggtaat caaataaatc agaataagtt tggcaaagtc
    40861 cacaggcgat acatcgttca ggtataagtg tgattttcat gttcatattt atattgtaat
    40921 aagaaaagta aaaaaaaaca aggagtaagg tatggcaaaa gaaccgtggc aagaagatat
    40981 ttatgatcaa gaagaatcaa gagcagggcg tcggcatcga aaccacggag gggctgatag
    41041 gatggctaat cgtattttga cgatcctagc tagtattttc tttgtaattg tggtggtgat
    41101 ggtcatcgtt ctcatctatc tatcatcggg ggggagtaat cgcacagtag ccttaaaaga
    41161 ctttcatgat tctgatgcaa gtgtagtaca aatctcatct tcaagcagtt ctcagcctga
    41221 gcagagttca gagccagaat ctacttctag tagttcagaa gaagctgcta atcctgaagg
    41281 aacgattaaa gttctcgcag gagaagggga agcagctatt gccgctcgtg caggaatctc
    41341 cattgctcag ttagaggcct tgaatcctgg gcacatggct acaggatctt ggtttgctaa
    41401 tccaggtgat gttataaaaa taaaatagga gccgatatga aaacaattca aattgctatt
    41461 gatggtcctg cttccagcgg taagagtacg gtcgcaaaga ttattgctaa ggattttgga
    41521 ttcacctacc ttgatacagg agctatgtat cgtgcagcga cctatatggc tcttaagaac
    41581 caattaggag ttgaagaagt cgaagccctt ctagccttgt tggaccagca tccaatcagc
    41641 tttggacgtt cagaaactgg agaccagctt gtttttgtag gagatgtgga tattacccat
    41701 cctatccgtg aaaatgaagt gaccaatcat gtttctgcta ttgcagcaat tcctgaagtg
    41761 cgtgagaaac tggtttctct ccaacaagaa attgcccagc aaggcgggat tgtcatggat
    41821 ggtcgcgata ttggaactgt tgtattgcca caagcagaat tgaaaatttt cctagtagct
    41881 tctgttgatg agagagcaga gcgtcgttac aaggaaaata ttgccaaggg aattgaaaca
    41941 gaccttgaaa ccctaaaaaa ggaaattgct gcgcgtgact acaaggatag tcatcgtgag
    42001 acttctcctc tcaaacaagc agaggatgct gtctaccttg atacaactgg tttgaacatt
    42061 caagaagtag ttgaaaaaat caaagcagaa gctgaaaaaa gaatgtaaat gtagaaaagc
    42121 cgatagattg atatcggttt ttttctaaat ttgtcaaaat gctgatttta gggtataata
    42181 gttgctgttc gagaaatttt gattttcaaa gaatagtgaa tgatgataag gagaaaccat
    42241 gaacaattta ccaaattgtc caaaatgtaa ctcagagtat gtctacgaag acggtgccct
    42301 actggtttgc ccagagtgtg ctcatgagtg gaatcctgct gaagttgcag aagtagaaga
    42361 aggtcttgtc gctatcgatg ccaacggaaa taaattggct gatggtgata tagtaactct
    42421 catcaaggac ttgaaagtaa aaggtgcgcc aaaagatttg aaacaaggga cgcgcgtgaa
    42481 aaatatccgc atcgtagaag gcgaccacaa tatcgactgt aagattgatg gttttggtgc
    42541 catgaaactt aaatcagagt ttgtgaggaa gatttaagca tgtcaaaaca ctataaactt
    42601 gtattttata gccgtatctt cttgtttcta gcggctttta cgggagttta tcttgaaatt
    42661 actaggcatg gtggttttgg gatgcttctc tattacacgg ttctgtccaa cctcttggta
    42721 actattttta ccctttatct tctaaaggtt atgagccgtg taggtgaaaa ttggcaaagg
    42781 ccaagtctct tgcgcttaaa aggtggggtc accatgagta tcatgattac ctgtgtgatt
    42841 taccatttcc tcttggcgcc cattgcgact aatttctata ccctagaaaa tttcctttgc
    42901 cactatatcg ttcccatctg gtttttagcg gataccctct tttttgacaa acagggtcaa
    42961 tacaagattt gggatccagc agtgtggacc attttaccct ttctgtatat gatgtttgct
    43021 ctttttaatg gcttggttct aaaactcaat attccaaatg ccaaggataa tcctttccct
    43081 tacttctttt tgaatgtgaa caagggttgg aatgttgtgt ttaagtggtg tctgattatc
    43141 tttgttgcct atatggtagc aggatttatt ttctacttta tcaagcaaat caagagaaag
    43201 tcatcctaat actcttcgaa aatctcttca aaccacgtta gtttccatct gcaacctcaa
    43261 aacactgttt tgaacaacct gcggctagct ttctagtttg ctctttgatt ttcattgagt
    43321 atgagataca agggattcat tttcgaattt aagaaggagt ctacaaacca atgaggcttc
    43381 ttcttttctt gcttatttga taactatcaa aaaagtagaa gattaagaga aatatagaaa
    43441 gagatttcat gaaacaattt ttagaacggg ccagcatttt ggctctctcc ctcgttttga
    43501 ttacctcctt ttccatttcg agtgccctac cagccatgtt tgactattat cagggttatt
    43561 ctaaggaaca aattgagctc ttggtgagct tgccttcctt tggaatcatg atgatgttac
    43621 tgctaaatgg tttcttagaa aaaatatttc ctgagcgctt acagattagt ttgggcttgc
    43681 tgattttatc attgagcggt acagctccct tctggtacca agcctatccc tttgtctttg
    43741 gaacacggct tctctttggt ttgggtcttg ggatgatcaa tgccaaggcc atttctatta
    43801 tcagtgaacg ctaccaagga aaaaggcgaa ttcagatgtt agggctacgc gcttctgcag
    43861 aggtcgttgg agcttctctc attaccttgg ccgtcggtca gttgttggcc tttggttgga
    43921 cagctatctt tctagcctat agtgctggat ttttggtgat gcccctttat ctgctctttg
    43981 tcccttatgg aaaatcaaag aaagaagtca agaaaagagc gaaggaagca agtcgtttaa
    44041 ctcgagaaat gaaaggcttg atttttacct tagctatcga agcggcagtt gtagtttgta
    44101 ccaatacagc tattaccatc cgtattccaa gtttgatggt ggaaagagga ttgggggatg
    44161 cccagttatc tagttttgtt cttagtatca tgcagttgat cgggattgtg gctggggtga
    44221 gtttttcttt cttgatttct atctttaaag agaaactgct cctctggtct ggtattacct
    44281 ttggcttggg gcaaatcgtg attgccttgt cttcatcctt gtgggtggta gtagcaggaa
    44341 gtgttctggc tggatttgcc tatagtgtag tcttgacgac ggtctttcaa cttgtctctg
    44401 aacgaattcc agctaaactc ctcaatcaag caacttcatt tgctgtatta ggctgtagtt
    44461 tcggagcctt tacgacccca tttgttctag gtgcaattgg cttactaact cacaatggga
    44521 tgttggtctt tagtatctta ggaggttggt tgattgtaat ctctatcttt gtcatgtacc
    44581 tacttcagaa gagagcttag gattgattcc taagtttttc ttttgatact caatgaaaat
    44641 caaagagcat agttgattga gtttggaata gtacgctgta gctgctaaaa tatttctaga
    44701 aattaatttg acttttctaa tagagttatt catatcttat ttcaatctac tatagaaagc
    44761 tagccgcagg ttgctcaaaa tagtgttttg aggttgcaga tggaaactga cgtggtttga
    44821 agagattttc gaagagtatg agatttttat acccatacaa tatttgtttt aggtccttgt
    44881 ttacagacta atttcttgat aaaatagagg ttatgacgag atataaagca actatttcct
    44941 atgatggtta tgcctttgat ggctttcagc gccagcctca tgcgcgtagc gttcaggaag
    45001 aaattgaaaa aaccttgacc agattaaata aagggcaaac cattactgtt cacggtgctg
    45061 gtaggacaga tagtggggtt catgccctgg gacaggtcat tcattttgac ctgccttatc
    45121 agatggatga ggagaaactc cgttttgcct tggataccca gtctcctgaa gatattgatg
    45181 tgatttcgat tgagcttgtg gcagatgatt ttcattgccg ttatgccaaa catagcaaga
    45241 cctatgagtt tattgtggat agaggacgtc ccaaaaatcc tatgcgccgt cactatgcca
    45301 cccactttcc ctacccactc gatgtggaac gaatgcagat tgcaatcaaa aagctagagg
    45361 gaacccatga ttttaccggt tttacagcct ctgggactag tgtagaggat aaggttcgca
    45421 ccatcacaga agctagttta atagtcgatg agacaggaca atttttgacc tttacctttt
    45481 caggaaatgg tttcttgtat aaacagattc gcaatatggt ggggactctt ctcaaaatcg
    45541 gtaacaaccg catgccagta gagcagattg ctctcatctt ggagaagaag gacaggcaac
    45601 ttgcaggtcc cactgcagca ccaaatggtt tgtatttaaa ggagattcgt tatgaagaat
    45661 aatcgtattt tagcactttc tggaaatgat atttttagtg gtggtggact gtcagctgat
    45721 ttggctacct ataccttgaa cggcttgcat gggtttgtag cagtgacttg tttgacagcc
    45781 ttgacagaaa aaggatttga agtctttcca actgatgata ccatttttca acatgaatta
    45841 gatagcttgc gtgatgtgga atttggggga attaagattg gtcttctccc tactgtcagt
    45901 gtggctgaga aggccttgga ctttatcaaa caacgcccag gagtacctgt ggtgttggat
    45961 cctgtcttgg tctgcaagga aacgcatgat gtagctgtca gtgagctctg ccaagagttg
    46021 attcgcttct tcccttatgt cagtgtgatt acgcctaatc tcccagaagc agaattatta
    46081 tccggtcagg aaattaaaac cttggaagac atgaaaactg cagcgcagaa attgcatgat
    46141 ttaggagcgc cagcagtcat tatcaaggga ggcaatcgtc ttagtcagga caaggctgtg
    46201 gatgtctttt atgatggaca gacctttact atcctagaaa atccagttat ccaaggccaa
    46261 aatgctggtg caggttgtac ctttgcctct agcattgcca gtcacctggt taaaggtgat
    46321 aaacttttgc cagcagtaga aagctctaag gctttcgttt atcgtgctat tgcacaagca
    46381 gatcagtatg gagtaagaca atatgaagca aacaaaaaca actaaaatcg cccttgtatc
    46441 cctattaacc gccctttctg tggttctagg ttatttctta aaattcccaa cacctacagg
    46501 aattctaact cttttagatg ctggtgtctt ctttgcggcc ttttactttg gtagtcgtga
    46561 aggagcggta gtcggaggac tagcaagttt cttgattgac ctcttatcag gctaccctca
    46621 gtggatgttc tttagcttgg tcaaccatgg cttgcaggga tttttcgcag gatttaaagg
    46681 aaaaagtcag tggttaggcc ttattttagc aactattgcc atggtaggag gctacgcctt
    46741 gggttctact ttgatgaatg gctgggcagc agccctccca gaaattctac cgaattttat
    46801 gcaaaatatg gtagggatga ttgtaggatt tattcttagt caaagtatca agaagattaa
    46861 gtaatactct tcgaaaatct cttcaaacca cgtcagcttc catctgcaac ctcaaaacac
    46921 tgttttgagc agcctgaggc tagctttcta gtttgcactt tgattttcat tgagtataaa
    46981 gaggttgagt aaaaagtatt tcaaataaga aaaacgcata gtatcaggtg ttgaatgaac
    47041 tgccccccaa aagttagaca gaaaaaatct aacttttggg gt
//
LOCUS       DBEJAU010000008        46485 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC323 isolate 683620
            SAMN38261939-rid24807223.denovo.008, whole genome shotgun sequence.
ACCESSION   DBEJAU010000008 DBEJAU010000000
VERSION     DBEJAU010000008.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261939
            Sequence Read Archive: SRR26833919
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 46485)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 46485)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576303.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576303.1
            Genome Coverage       :: 154x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/19/2025 01:05:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,121
            CDSs (total)                      :: 2,078
            Genes (coding)                    :: 1,943
            CDSs (with protein)               :: 1,943
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 36
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 72 of 135
            Pseudo Genes (incomplete)         :: 63 of 135
            Pseudo Genes (internal stop)      :: 51 of 135
            Pseudo Genes (multiple problems)  :: 46 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..46485
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261939-rid24807223.denovo.008"
                     /strain="GPSC323"
                     /isolate="683620"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            complement(846..1259)
                     /gene="ndk"
                     /locus_tag="ACL29Z_000523"
     CDS             complement(846..1259)
                     /gene="ndk"
                     /locus_tag="ACL29Z_000523"
                     /EC_number="2.7.4.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000438285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004550 - nucleoside diphosphate kinase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside-diphosphate kinase"
                     /protein_id="HGR0068878.1"
                     /translation="MEQTFFIIKPDGVKRGLVGEVLKRIEQRGFTIEKLEFRSQVSEE
                     LIDQHYQDLVGQSFYLPIREFMTSGPVLVGVISGPKVIETWRTMMGATRPEEALPGTI
                     RGDFAKAAGENEVIQNVVHGSDSEESAKREIALWF"
     gene            complement(1370..5047)
                     /gene="rpoC"
                     /locus_tag="ACL29Z_000524"
     CDS             complement(1370..5047)
                     /gene="rpoC"
                     /locus_tag="ACL29Z_000524"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000228741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003899 - DNA-directed 5'-3' RNA
                     polymerase activity [Evidence IEA];
                     GO_process: GO:0006351 - DNA-templated transcription
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta'"
                     /protein_id="HGR0068879.1"
                     /translation="MVDVNRFKSMQITLASPSKVRSWSYGEVKKPETINYRTLKPERE
                     GLFDEVIFGPTKDWECACGKYKRIRYRGIVCDRCGVEVTRTKVRRERMGHIELKAPVS
                     HIWYFKGIPSRMGLTLDMSPRALEEVIYFAAYVVIDPKDTPLEHKSIMTEREYRERLR
                     EYGYGSFVAKMGAEAIQDLLKQVDLEKEIAELKEELKTATGQKRVKAIRRLDVLDAFY
                     KSGNKPEWMILNILPVIPPDLRPMLQLDGGRFASSDLNDLYRRVINRNNRLARLLELN
                     APGIIVQNEKRMLQEAVDALIDNGRRGRPITGPGSRPLKSLSHMLKGKQGRFRQNLLG
                     KRVDFSGRSVIAVGPTLKMYQCGVPREMAIELFKPFVMREIVARDIVQNVKAAKRLVE
                     RGDERIWDILEEVIKEHPVLLNRAPTLHRLGIQAFEPVLIDGKALRLHPLVCEAYNAD
                     FDGDQMAIHVPLSEEAQAEARILMLAAEHILNPKDGKPVVTPSQDMVLGNYYLTMEEA
                     GREGEGMVFKDRDEAVMAYRNGYVHLHSRVGIATDSLNKPWTEEQRHKVLLTTVGKIL
                     FNDIMPEGLPYLQEPNNANLTEGVPAKYFLPLGGDIKEAISNLELNPPFKKKNLGNII
                     AEIFKRFRTTETSALLDRMKNLGYHHSTLAGLTVGIADIPVVDDKTEIIEESHKRVEQ
                     ITKQFRRGMITDDERYNAVTAEWRAAREKLEKRLIANQDPKNPIVMMMDSGARGNISN
                     FSQLAGMRGLMAAPNGRIMELPILSNFREGLSVLEMFFSTHGARKGMTDTALKTADSG
                     YLTRRLVDVAQDVIIREDDCGTDRGLLIRSIAEGKEMIESLEERLNGRYTKKTVKHPE
                     TGAVIIGPNELITEDKAREIVNAGVEEVTIRSVFTCNTRHGVCRHCYGINLATGDAVE
                     VGEAVGTIAAQSIGEPGTQLTMRTFHTGGVASNTDITQGLPRVQEIFEARNPKGEAVI
                     TEVKGQVTAIEEDASTRTKKVFVKGETGEGEYVVPFTARMRVEVGGQVARGAALTEGS
                     IQPKRLLAVRDVLSVETYLLGEVQKVYRSQGVEIGDKHIEVMVRQMIRKVRVMDPGDT
                     DLLMGTLMDINDFTDANKDVLIAGGVPATGRPVLMGITKASLETNSFLSAASFQETTR
                     VLTDAAIRGKKDHLLGLKENVIIGKIIPAGTGMARYRNLEPHAVNEEEYLNPPVEEEG
                     NEETTEVVVDTAVETVEETVE"
     gene            complement(5080..8691)
                     /gene="rpoB"
                     /locus_tag="ACL29Z_000525"
     CDS             complement(5080..8691)
                     /gene="rpoB"
                     /locus_tag="ACL29Z_000525"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000907130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003899 - DNA-directed 5'-3' RNA
                     polymerase activity [Evidence IEA];
                     GO_process: GO:0006351 - DNA-templated transcription
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta"
                     /protein_id="HGR0068880.1"
                     /translation="MAGHDVQYGKHRTRRSFSRIKEVLDLPNLIEIQTDSFKAFLDHG
                     LKEVFEDVLPISNFTDTMELEFVGYEIKEPKYTLEEARIHDASYSAPIFVTFRLINKE
                     TSEIKTQEVFFGDFPIMTEMGTFIINGGERIIVSQLVRSPGVYFNDKVDKNGKVGYGS
                     TVIPNRGAWLELESDSKDITYTRIDRTRKIPFTTLVRALGFSGDDEIFDIFGDSELVR
                     NTVEKDIHKNPMDSRTDEALKEIYERLRPGEPKTAESSRSLLVARFFDPRRYDLAAVG
                     RYKINKKLNVKTRLLNQTIAEPLVDPETGEILVEAGTIMTRSVIESIESHLDGDLNKI
                     VYIPNDAAVVTEPVVLQKFKVIAPTDPDRVVTIIGNANPDDKVRTVTPADILAEMSYF
                     LNLAEGLGRVDDIDHLGNRRIRAVGELLANQVRLGLSRMERNVRERMSVQDNEVLTPQ
                     QIINIRPVTAAVKEFFGSSQLSQFMDQHNPLSELSHKRRLSALGPGGLTRDRAGYEVR
                     DVHYTHYGRMCPIETPEGPNIGLINNLSSYGHLNKYGFVQTPYRKVDRETGVVTNEIV
                     WLTADEEDEYTVAQANSRLNEDGTFAEKIVMGRHQGVNQEYPANIVDYMDVSPKQVVA
                     VATACIPFLENDDSNRALMGANMQRQAVPLINPQAPYVGTGMEYQAAHDSGAAVIAQY
                     DGKVTYADADKVEVRREDGSLDVYHIQKFRRSNSGTAYNQRTLVKVGDVVEKGDFIAD
                     GPSMENGEMALGQNPIVAYMTWEGYNFEDAVIMSERLVKDDVYTSVHLEEYESETRDT
                     KLGPEEITREIPNVGEDALKDLDEMGIIRIGAEVKEGDILVGKVTPKGEKDLSAEERL
                     LHAIFGDKSREVRDTSLRVPHGADGVVRDVKIFTRVNGDELQSGVNMLVRVYIAQKRK
                     IKVGDKMAGRHGNKGVVSRIVPVEDMPYLPDGTPVDIMLNPLGVPSRMNIGQVMELHL
                     GMAARTLGIHIATPVFDGASSEDLWSTVKEAGMDSDAKTILYDGRTGEPFDNRVSVGV
                     MYMIKLHHMVDDKLHARSVGPYSTVTQQPLGGKAQFGGQRFGEMEVWALEAYGASNVL
                     QEILTYKSDDINGRLKAYEAITKGKPIPKPGVPESFRVLVKELQSLGLDMRVLDEDDQ
                     EVELRDLDEGMDEDVIHVDDLEKAREKAAQEAKAAFEAEEAEKATKAEATEEAAEQE"
     gene            9107..9177
                     /locus_tag="ACL29Z_000526"
     tRNA            9107..9177
                     /locus_tag="ACL29Z_000526"
                     /product="tRNA-Cys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:9139..9141,aa:Cys,seq:gca)
     gene            complement(9375..10706)
                     /locus_tag="ACL29Z_000527"
     CDS             complement(9375..10706)
                     /locus_tag="ACL29Z_000527"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000390004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="hemolysin family protein"
                     /protein_id="HGR0068881.1"
                     /translation="MEDPSSQNLLLQFVLLFILTVLNAFFSATEMAMVSLNRARVEQK
                     AEEGDRRYIRLLKVLENPNHFLSTIQVGITLITILSGASLTNTLGRVIASWLGNGETA
                     QAVATFLSLAFLTYISIVFGELYPKRIALNLKDALAIRTAPVIIGIGKLVSPFVWLLA
                     ASTNFLSHLTPMSFDDADEKMTRDEIAYMLTNSEETLDADEIEMLQGVFSLDELMARE
                     VMVPRTDAFMVDIQDDSQAIIQSILKQNYSRIPVYDGDKDNVIGIIHTKSLLKAGFVD
                     GFDNIVWKRILQDPLFVPETIFVDDLLKELRNTQRQMAILLDEYGGMAGLVTLEDLLE
                     EIVGEIDDETDKAAIDVHQIGEDTYIVQGTMTLNDFNNYFDVELESDDVDTIAGYYLT
                     GVGTIPTTEKLSYELVSQNKQFILTNDKVKNGRVTKVKVQITEVEIEEETE"
     gene            complement(10935..11759)
                     /gene="endA"
                     /locus_tag="ACL29Z_000528"
     CDS             complement(10935..11759)
                     /gene="endA"
                     /locus_tag="ACL29Z_000528"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001036779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-entry nuclease EndA"
                     /protein_id="HGR0068882.1"
                     /translation="MNKKTRQTLIGLLVLLLLSTGSYYIKQMPSAPNSPKTNLSQKKQ
                     ASEAPSQALAESVLTDAVKSQIKGSLEWNGSGAFIVNGNKTNLDAKVSSKPYADNKTK
                     TVGKETVPTVANALLSKATRQYKNRKETGNGSTSWTPPGWHQVKNLKGSYTHAVDRGH
                     LLGYALIGGLDGFDASTSNPKNIAVQTAWANQAQAEYSTGQNYYESKVRKALDQNKRV
                     RYRVTLYYASNEDLVPSASQIEAKSSDGELEFNVLVPNVQKGLQLDYRTGEVTVTQ"
     gene            complement(11798..11986)
                     /locus_tag="ACL29Z_000529"
     CDS             complement(11798..11986)
                     /locus_tag="ACL29Z_000529"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004245549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta"
                     /protein_id="HGR0068883.1"
                     /translation="MNKKSSYVVKRLLLVIIVLILGTLALGIGLMVGYGILGKGQDPW
                     AILSPAKWQELIHKFTGN"
     gene            complement(11979..13262)
                     /gene="murA"
                     /locus_tag="ACL29Z_000530"
     CDS             complement(11979..13262)
                     /gene="murA"
                     /locus_tag="ACL29Z_000530"
                     /EC_number="2.5.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397009.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008760 - UDP-N-acetylglucosamine
                     1-carboxyvinyltransferase activity [Evidence IEA];
                     GO_process: GO:0019277 - UDP-N-acetylgalactosamine
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine
                     1-carboxyvinyltransferase"
                     /protein_id="HGR0068884.1"
                     /translation="MDKIVVQGGDNRLVGSVTIEGAKNAVLPLLAATILASEGKTVLQ
                     NVPILSDVFIMNQVVGGLNAKVDFDEEAHLVKVDATGDITEEAPYKYVSKMRASIVVL
                     GPILARVGHAKVSMPGGCTIGSRPIDLHLKGLEAMGVKISQTAGYIEAKAERLHGAHI
                     YMDFPSVGATQNLMMAATLADGVTVIENAAREPEIVDLAILLNEMGAKVKGAGTETIT
                     ITGVEKLHGTTHNVVQDRIEAGTFMVAAAMTGGDVLIRDAVWEHNRPLIAKLLEMGVE
                     VIEEDEGIRVRSQLENLKAVHVKTLPHPGFPTDMQAQFTALMTVAKGESTMVETVFEN
                     RFQHLEEMRRMGLHSEIIRDTARIVGGQPLQGAEVLSTDLRASAALILTGLVAQGETV
                     VGKLVHLDRGYYGFHEKLAQLGAKIQRIEASDEDE"
     gene            complement(13286..13516)
                     /locus_tag="ACL29Z_000531"
     CDS             complement(13286..13516)
                     /locus_tag="ACL29Z_000531"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014017351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1146 family protein"
                     /protein_id="HGR0068885.1"
                     /translation="MVQLLFTLSSHMFFIYVSFYLLKDLVRWEKVLKVTDDNTRKVRL
                     LVAFFSIVIGYILSSFFISLYHLWQEALRGLL"
     gene            complement(13574..14611)
                     /locus_tag="ACL29Z_000532"
     CDS             complement(13574..14611)
                     /locus_tag="ACL29Z_000532"
                     /EC_number="3.4.21.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001813016.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SepM family pheromone-processing serine
                     protease"
                     /protein_id="HGR0068886.1"
                     /translation="MKKKIRWPLYVIAALIVTFLAFVVPLPYYIEVPGGSEDIRQVLK
                     VNDTEDKEAGAYQFVTVGVQHATLAHMIYAWLTPFTDIRSAQETTGGSSDVEFMRINQ
                     FYMQTSQNMAKYQGLKTAGKDIELKYFGVYVLNVTDNSTFKEILNISDTVTAVNDQTF
                     DSSKDLIDYVSSQKLGDSVKVTYEEDGQTKSAEGKIITLENGKNGIGIGLIDRTEVIS
                     NVPISFSTAGIGGPSAGLMFSLAIYTQIAHPDLRNGRIVAGTGTIDRDGNVGDIGGID
                     KKVVASARAGAAIFFAPDNPVSEEEQKAHPDAKNNYQTALEAAKTIKTDMKIVPVKTL
                     QDAIDYLKNNP"
     gene            complement(14595..15083)
                     /gene="coaD"
                     /locus_tag="ACL29Z_000533"
     CDS             complement(14595..15083)
                     /gene="coaD"
                     /locus_tag="ACL29Z_000533"
                     /EC_number="2.7.7.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001280753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004595 - pantetheine-phosphate
                     adenylyltransferase activity [Evidence IEA];
                     GO_process: GO:0015937 - coenzyme A biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pantetheine-phosphate adenylyltransferase"
                     /protein_id="HGR0068887.1"
                     /translation="MSDKIGLFTGSFDPMTNGHLDIIERASRLFDKLYVGIFFNPHKQ
                     GFLPLENRKRGLEKALGHLENVEVVASHDELVVDVAKRLGATFLVRGLRNAADLQYEA
                     SFDYYNHQLSSDIETIYLHSRPEHLYISSSGVRELLKFGQDIACHVPESILEEIRNEK
                     KD"
     gene            complement(15073..15612)
                     /gene="rsmD"
                     /locus_tag="ACL29Z_000534"
     CDS             complement(15073..15612)
                     /gene="rsmD"
                     /locus_tag="ACL29Z_000534"
                     /EC_number="2.1.1.171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006147838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0052913 - 16S rRNA
                     (guanine(966)-N(2))-methyltransferase activity [Evidence
                     IEA];
                     GO_process: GO:0031167 - rRNA methylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (guanine(966)-N(2))-methyltransferase
                     RsmD"
                     /protein_id="HGR0068888.1"
                     /translation="MKIVSGIYGGRPLKTLEGKTTRPTSDKVRGAIFNMIGPYFEGGR
                     VLDLYAGSGGLSIEAVSRGMSSAVLVERDRKAQTIVAENIQMTKEVGKFQLLKMDAER
                     ALEQVSGEFDLVFLDPPYAKEQIVADIEKMAKRELFSEDVMVVCETDKAVELPEEIAC
                     LGIWKEKIYGISKVTVYVR"
     gene            complement(15677..16669)
                     /gene="asnA"
                     /locus_tag="ACL29Z_000535"
     CDS             complement(15677..16669)
                     /gene="asnA"
                     /locus_tag="ACL29Z_000535"
                     /EC_number="6.3.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016502595.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004071 - aspartate-ammonia ligase
                     activity [Evidence IEA];
                     GO_process: GO:0006529 - asparagine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate--ammonia ligase"
                     /protein_id="HGR0068889.1"
                     /translation="MKKSFIHQQEEISFVKNTFTQYLKDKLEVVEVQGPILSKVGDGM
                     QDNLSGVENPVSVKVLQIPDATYEVVHSLAKWKRHTLARFGFGEGEGLFVHMKALRPD
                     EDSLDATHSVYVDQWDWEKVIPNGKRNIVYLKETVEKIYKAIRLTELAVEARYDIESI
                     LPKQITFIHTEELVERYPDLTPKERENAICKEFGAVFLIGIGGELPDGKPHDGRAPDY
                     DDWTSESENGYKGLNGDILVWNESLGGAFELSSMGIRVDEETLRRQVEITGDEDRLEL
                     EWHKSLLNGLFPLTIGGGIGQSRMAMFLLRKRHIGEVQTSVWPQEVRDTYENIL"
     gene            complement(16780..17463)
                     /locus_tag="ACL29Z_000536"
     CDS             complement(16780..17463)
                     /locus_tag="ACL29Z_000536"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015545711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Bax inhibitor-1/YccA family protein"
                     /protein_id="HGR0068890.1"
                     /translation="MNHTIIHDRAGLNQFYAKVYAFVGLGIGLSALVSGLMLTVFQSQ
                     LVYLLMQGRLWLTIATFAELALVFVASSMASRNSPAALPVFLLYSVLNGFTLSFVVAF
                     YTPGTVLSAFVSSALLFFVMAAVGIFTKKDLSGIGRAMMAALIGLLIAMVVNIFLASG
                     FFDYMISVAMVLVFSGLIAWDNQKIRLAYEQSQGRVATGWVVSMALSIYLDFINLFLS
                     ILRIFGRND"
     gene            complement(17519..18259)
                     /locus_tag="ACL29Z_000537"
     CDS             complement(17519..18259)
                     /locus_tag="ACL29Z_000537"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000152696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008173 - RNA methyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0016740 - transferase activity [Evidence
                     IEA];
                     GO_process: GO:0001510 - RNA methylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TrmH family RNA methyltransferase"
                     /protein_id="HGR0068891.1"
                     /translation="MTIITSKANSVVKNAKKLHQKKYRKSAYLIEGWHLFEEAVQAGV
                     TIEKIFALENYRNQLAAFPQTVWISEDILLDLADSQTPQGIVAVVQKEEVGQADLSQG
                     KFLFLEDVQDPGNVGTIIRTADAAGFTGVIVSDKSADIYSLKTLRSMQGSHFHLPIYR
                     MTSQALLDETKKVAIPVLATTLSKDSVDYRELPSIENFVLVMGNEGQGISPLMAESAD
                     QLVHISMKGQAESLNVAVATGILIFHLS"
     gene            18293..18571
                     /locus_tag="ACL29Z_000538"
     CDS             18293..18571
                     /locus_tag="ACL29Z_000538"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001174612.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acylphosphatase"
                     /protein_id="HGR0068892.1"
                     /translation="MQKVRMIAQGRVQGVGFRWGVYSLALEIGGITGRVWNNDDGTVE
                     ILAQADSSAIMAKFIQEIRKGPTPFSKVSYLDVKLSNFPPYSDFKIAN"
     gene            18649..19575
                     /gene="yidC"
                     /locus_tag="ACL29Z_000539"
     CDS             18649..19575
                     /gene="yidC"
                     /locus_tag="ACL29Z_000539"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000835957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertase YidC"
                     /protein_id="HGR0068893.1"
                     /translation="MKSIKRFAFSAMGVAMLLVLTGCVNVDKTTGQPTGFIWNTIGAP
                     MAEAIKYFATDKGLGFGVAIIIVTIIVRLIILPLGIYQSWKATLHSEKMNALKHVLEP
                     HQTRLKEATTQEEKLEAQQALFAAQKEHGISMFGGVGCFPILLQMPFFSAIYFAAQHT
                     EGVAQASYLGIPLGSPSMILVACAGVLYYLQSLLSLHGVEDEMQREQIKKMIYMSPLM
                     IVVFSLFSPASVTLYWVVGGFMMILQQFIVNYIVRPKLRKKVREELAKNPPKASAFSK
                     PSGRKDVTPEQPTAITSKKKHKNRNAGKQRSR"
     gene            complement(19650..20444)
                     /gene="pflA"
                     /locus_tag="ACL29Z_000540"
     CDS             complement(19650..20444)
                     /gene="pflA"
                     /locus_tag="ACL29Z_000540"
                     /EC_number="1.97.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001288284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0043365 -
                     [formate-C-acetyltransferase]-activating enzyme activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate formate-lyase-activating protein"
                     /protein_id="HGR0068894.1"
                     /translation="MSEETIDYGQVTGMVHSTESFGSVDGPGIRFIVFLQGCHMRCQY
                     CHNPDTWAMESNKSRERTVDDVLTEALRYRGFWGNKGGITVSGGEALLQIDFLIALFT
                     KAKEQGIHCTLDTCALPFRNKPRYLEKFDKLMAVTDLVLLDIKEINEEQHKIVTSQTN
                     KNILACAQYLSDIGKPVWIRHVLVPGLTDRDDDLIELGKFVKTLKNVDKFEILPYHTM
                     GEFKWRELGIPYSLEGVKPPTADRVKNAKKLMDTESYQDYMKRVHG"
     gene            complement(20570..21820)
                     /locus_tag="ACL29Z_000541"
     CDS             complement(20570..21820)
                     /locus_tag="ACL29Z_000541"
                     /EC_number="4.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000856498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008836 - diaminopimelate decarboxylase
                     activity [Evidence IEA];
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA];
                     GO_process: GO:0009089 - lysine biosynthetic process via
                     diaminopimelate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="diaminopimelate decarboxylase"
                     /protein_id="HGR0068895.1"
                     /translation="MKTPFINREELEAIVAEFPTPFHLYDEKGIREKARAVNQAFSWN
                     KGFKEYFAVKATPTPAILKILQEEGCGVDCSSYVELLMSHKLDFLGSEIMFSSNNTPD
                     KEYAYARELGATINLDAFEDIEHLERVAGIPEIISCRYNPGGVFELGTDIMDNPGEAK
                     FGMTKDQLFEAFAILKEKGAKTFGIHSFLASNTVTHLYYPELARQLFELAVEIKEKLG
                     ISLDFINLSGGIGVNYRPDQEPNDIALIGEGVRKVYEEVLTSAGLGQVKIFTELGRFM
                     LAPHGALVTRVTHKKETYRTYLGVDASAVNLMRPAMYGAYHHISNVTHPDGPAEAVDV
                     VGSLCENNDKFAVNRELPHTEIGDLLVIHDTGAHGFSMGYQYNAKLRSAEILYTEEGK
                     ARQIRRAERPEDYFATLYGFDFEE"
     gene            complement(21887..22714)
                     /gene="purR"
                     /locus_tag="ACL29Z_000542"
     CDS             complement(21887..22714)
                     /gene="purR"
                     /locus_tag="ACL29Z_000542"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004242125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA];
                     GO_process: GO:0009116 - nucleoside metabolic process
                     [Evidence IEA];
                     GO_process: GO:0045892 - negative regulation of
                     DNA-templated transcription [Evidence IEA];
                     GO_process: GO:0045982 - negative regulation of purine
                     nucleobase metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pur operon repressor"
                     /protein_id="HGR0068896.1"
                     /translation="MKLRRSDRMVVISNYLINNPYKLTSLNTFAEKYESAKSSISEDI
                     VIIKRAFEEIEIGHIQTVTGAGGGVIFTPSISSQDAKEMVEDLRTKLSESDRILPGGY
                     IYLSDLLSTPAILKHIGRIIAKSFMDQKIDAVMTVATKGVPLANAVANVLNVSFVIVR
                     RDLKITEGSTVSVNYVSGSSGDRIEKMFLSKRSLKAGSRVLIVDDFLKGGGTVNGMIS
                     LLREFDSELAGVAVFADNAQEEREKQFDYKSLLKVTNIDVKNQAIDVEVGNIFDEDK"
     gene            complement(22981..23922)
                     /locus_tag="ACL29Z_000543"
     CDS             complement(22981..23922)
                     /locus_tag="ACL29Z_000543"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3'-5' exoribonuclease YhaM family protein"
                     /protein_id="HGR0068897.1"
                     /translation="MKISHMKKDELFEGFYLIKSADLRQTRAGKNYLAFTFQDDSGEI
                     DGKLWDAQPHNIEAFTAGKVVHMKGRREVYNNTPQVNQITLRLPQAGEPNDPADFKVK
                     SPVDVKEIRDYMSQMIFKIENPVWQRIVRNLYTKYDKEFYSYPAAKTNHHAFETGLAY
                     HTATMVRLADAISEVYPQLNKSLLYAGIMLHDLAKVIELTGPDQTEYTVRGNLLGHIA
                     LIDSEITKTVMELGIDDTKEEVVLLRHVILSHHGLLEYGSPVRPRIMEAEIIHMIDNL
                     DASMMMMSTALALVDKGEMSNKIFAMDNRSFYKPDLD"
     gene            complement(23912..25168)
                     /gene="rmuC"
                     /locus_tag="ACL29Z_000544"
     CDS             complement(23912..25168)
                     /gene="rmuC"
                     /locus_tag="ACL29Z_000544"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000444769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA recombination protein RmuC"
                     /protein_id="HGR0068898.1"
                     /translation="MESLLILLLIANLAGLFLIWQRQDRQEKHLSKSLEDQADHLSDQ
                     LDYRFDQARQASQLDQKDLEVAVSDRLQEVRIELHQGLTQVRQEMTDNLLQTRDKTDQ
                     RLQALQESNEQRLEQMRQTVEEKLEKTLQTRLQASFETVSKQLESVNRGLGEMQTVAR
                     DVGALNKVLSGTKTRGILGELQLGQIIEDIMTPAQYEREYATVENSSERVEYAIKLPG
                     QGDQEYVYLPIDSKFPLADYYRLEEAYETGDKDEIERCRKSLLASVKRFAKDIKSKYI
                     APPRTTNFGILFVPTEGLYSEIVRNPVFFDDLRREEQIIVAGPSTLSALLNSLSVGFK
                     TLNIQKSADHISKTLASVKTEFGKFGGILVKAQKHLQHASGNIDELLNRRTIAIERTL
                     RHIELSEGEPALDLLYFQENEEEYED"
     gene            complement(25170..25832)
                     /locus_tag="ACL29Z_000545"
     CDS             complement(25170..25832)
                     /locus_tag="ACL29Z_000545"
                     /EC_number="2.7.6.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000006147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004788 - thiamine diphosphokinase
                     activity [Evidence IEA];
                     GO_process: GO:0006772 - thiamine metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine diphosphokinase"
                     /protein_id="HGR0068899.1"
                     /translation="MSEYKLSENNWTRVAVFAGGNRGHYRTDFDAFVGVDRGSLWVLE
                     EDLPLALAVGDFDSVTEEERQVIQKRAQHFVQARPEKDDTDLELALLTIFEQNPQAEV
                     TIFGALGGRIDHMLANVFLPSNPKLAPYMRQIEIEDGQNLIAYCSEGTSQLEPRSDYD
                     YLAFMPVRDSQLTILGAKYELTEENFFFKKVYASNEYIDREVSVTCPDGYVVVLHSKD
                     RR"
     gene            complement(25795..26451)
                     /gene="rpe"
                     /locus_tag="ACL29Z_000546"
     CDS             complement(25795..26451)
                     /gene="rpe"
                     /locus_tag="ACL29Z_000546"
                     /EC_number="5.1.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004750 - D-ribulose-phosphate 3-epimerase
                     activity [Evidence IEA];
                     GO_process: GO:0006098 - pentose-phosphate shunt [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribulose-phosphate 3-epimerase"
                     /protein_id="HGR0068900.1"
                     /translation="MSQYKIAPSILAADYANFEREIKRLEATGAEYAHIDIMDSHFVP
                     QISFGAGVVESLRPHSKMVFDCHLMVSNPEHHLEDFARAGADIISIHVEATPHIHGAL
                     QKIRSLGVKPSVVINPGTPVEAIKHVLHLVDQVLVMTVNPGFGGQAFLPETMDKVREL
                     VALREEKGLNFEIEVDGGIDDQTIAQAKEAGATVFVAGSYVFKGEVNERVQTLRKQLD
                     "
     gene            complement(26462..27340)
                     /gene="rsgA"
                     /locus_tag="ACL29Z_000547"
     CDS             complement(26462..27340)
                     /gene="rsgA"
                     /locus_tag="ACL29Z_000547"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_function: GO:0043022 - ribosome binding [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome small subunit-dependent GTPase A"
                     /protein_id="HGR0068901.1"
                     /translation="MQGQIIKALAGFYYVESDGQVYQTRARGNFRKKGHTPYVGDWVD
                     FSAEENSEGYILKIHERKNSLVRPPIVNIDQAVVIMSVKEPDFNSNLLDRFLVLLEHK
                     GIHPIVYISKMDLLEDRGELDFYRQTYGDIGYDFVTSKEELLSLLTGKVTVFMGQTGV
                     GKSTLLNKLVPDLNLETGEISDSLGRGRHTTRAVSFYNLNGGKIADTPGFSSLDYEVS
                     RAEDLNQAFPEIATVSRDCKFRTCTHTHEPSCAVKPAVEEGVIATFRFDNYLQFLSEI
                     ENRRETYKKVSKKIPK"
     gene            complement(27342..28214)
                     /gene="rsmA"
                     /locus_tag="ACL29Z_000548"
     CDS             complement(27342..28214)
                     /gene="rsmA"
                     /locus_tag="ACL29Z_000548"
                     /EC_number="2.1.1.182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000179 - rRNA
                     (adenine-N6,N6-)-dimethyltransferase activity [Evidence
                     IEA];
                     GO_process: GO:0006364 - rRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA
                     (adenine(1518)-N(6)/adenine(1519)-N(6))-
                     dimethyltransferase RsmA"
                     /protein_id="HGR0068902.1"
                     /translation="MRIADYSVTKAVLERHGFTFKKSFGQNFLTDTNILQKIVDTAEI
                     DDQVNVIEIGPGIGALTEFLAERAAQVMAFEIDHRLVPILADTLRDFDNVTVVNEDIL
                     KVDLAQHIQNFKNPNLPIKVVANLPYYITTPILMHLIESGIPFSEFVVMMQKEVADRI
                     SAQPNTKAYGSLSIAVQYYMTAKVAFIVPRTVFVPAPNVDSAILKMVRRPEPAVAVED
                     ENFFFKVSKASFIHRRKTLWNNLTGYFGKTEEVKDKLTKALDQAGLSPSVRGEALSLA
                     EFAGLADALKGQGL"
     gene            complement(28345..28653)
                     /locus_tag="ACL29Z_000549"
     CDS             complement(28345..28653)
                     /locus_tag="ACL29Z_000549"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000333253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0068903.1"
                     /translation="MCEKIRIRRVSDYPSARGGLEDILIMENMTNHLLLVQIRVHGYL
                     LDFASIEGQRQKHYRLKNLPQTVELTVDDVEEDVDLTLPENRSYQEADFFERMFRENC
                     "
     gene            complement(28646..29287)
                     /locus_tag="ACL29Z_000550"
     CDS             complement(28646..29287)
                     /locus_tag="ACL29Z_000550"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000565534.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGR0068904.1"
                     /translation="MIDIQGLEKKFNDRAIFSGLNLKLEKGKVYALIGKSGSGKTTLL
                     NILGKLEKIDGGRVLYQGKDLKTIPTREYFRDQMGYLFQNFGLLENQSIKENLDLGFV
                     GQKISKVERLERQVGALEKVNLGYLDLEQKIYTLSGGEAQRVALAKTILKNPPLILAD
                     EPTAALDPENSEEVMNLLVDLKDENRIIIIATHNPLVWNKADEIIDMRKLAHV"
     gene            complement(29289..31319)
                     /locus_tag="ACL29Z_000551"
     CDS             complement(29289..31319)
                     /locus_tag="ACL29Z_000551"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000825281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-associated integral membrane family
                     protein"
                     /protein_id="HGR0068905.1"
                     /translation="MKRLFILISMVLVSLYMVITSVDHREEILFGNYPSVDVTGMMIN
                     QPVASREEVTEALSHLAVEHNSLIARRIVEPNEAGETLFTYATYGEGELPEGLTISSK
                     ESAETSDLLGSYLIVSGSLDGVSLQTTLKELGYQGFVSNGEDPFSIVLLLTATPMVLL
                     SLAIFLLTFMSLTLIYRIKSLRQAGIRLIAGESLFGVALRPVLEDVRQLICSVLVSSL
                     LGLGILWYQGALFMATVQLVIIALLLYGLTLAGISTLLSVVYLLGLQENSLVDLLKGK
                     LPLKRMMTLMMVGQLLAVLVVGSSATALLPHYREMQEMERASNKWSQSSDRYRLSFGW
                     SSAFADEEGTRKDNREWQTFTEERLANTDSFYIMSNVDNFSDGAEVDLDGNRLSDYTP
                     SGNVIYVSPRYLIEEKITVSSEFMDKMQNLSEGEFGLILPESLREQSTYYQGLFTDYL
                     QNFSSESVEVTSQKYYLPQVRLAFTETGQERFLYNDGYKTTRQYLKDPIIVVLTPQAT
                     GTRPVAGMLWGTTANSALKLDRYGDSITALKEQGLYHKVSYLVKSQLFFAKVLNDKRV
                     EFYSLLIGTILTLSTAILLFDSMNLLYFEQFRRELMIKRLAGMTIYELHGKYLLAQGG
                     VLLLGLVLSSILTRDGLISALVVALFTLNALLILVRQDKKEEAGSMAVLKGK"
     gene            complement(31396..31692)
                     /locus_tag="ACL29Z_000552"
     CDS             complement(31396..31692)
                     /locus_tag="ACL29Z_000552"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000815395.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactococcin 972 family bacteriocin"
                     /protein_id="HGR0068906.1"
                     /translation="MKQTVKKLALVASIAATLGGSVAVASAAVQYPEGGVWTYGSGNG
                     GAYSNYYHPSKYHSSTVVSRKTGSSDKGYAGAGGTSRAWIRTSWGEKVAFYYNV"
     gene            complement(32012..32911)
                     /locus_tag="ACL29Z_000553"
     CDS             complement(32012..32911)
                     /locus_tag="ACL29Z_000553"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000904853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XRE family transcriptional regulator"
                     /protein_id="HGR0068907.1"
                     /translation="MLIGQKIKEIRIEKGISRPDFCGDEQELTVRQLSRIESGASQPS
                     LPKLAYIARRLGVPVYSLLPDFSALPSAYLELKYQILREPIYGKEEEYDKKEACLEEI
                     YKTYFDNLPKEEQLACEVLQACLDTSRTRRPEYAELILEEHMPQIIEKEAYSINDMLL
                     IRLFFYQMLIRKDLAKFINQIEKLMLFLLEQKKVTQIENYFIIRDTLISGMCCLEKVG
                     VTDCFNDYLSCLQEIMDKTQDYQKKPLVFMFLWKQALRVERDFSLAESFYQSSKTFAK
                     LIGDGFLVKKLTEEWQEDVKKYL"
     gene            complement(32983..33543)
                     /gene="rnmV"
                     /locus_tag="ACL29Z_000554"
     CDS             complement(32983..33543)
                     /gene="rnmV"
                     /locus_tag="ACL29Z_000554"
                     /EC_number="3.1.26.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000660004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0043822 - ribonuclease M5 activity
                     [Evidence IEA];
                     GO_process: GO:0006364 - rRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease M5"
                     /protein_id="HGR0068908.1"
                     /translation="MKERISQVIVVEGRDDTVNLKRYFDVETYETRGSAINDQDIERI
                     QRLHQRHGVIVFTDPDFNGERIRRMIMTAIPTVQHAFLKRDEAVPKSKTKGRSLGIEH
                     ASYEDLKTALAQVTEQFEHESQFDISRSDLIRLGFLAGADSRKRREYLGETLRIGYSN
                     GKQLLKRLELFGVTLAEVEEAMKSYE"
     gene            complement(33543..34316)
                     /locus_tag="ACL29Z_000555"
     CDS             complement(33543..34316)
                     /locus_tag="ACL29Z_000555"
                     /EC_number="3.1.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000575597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TatD family hydrolase"
                     /protein_id="HGR0068909.1"
                     /translation="MIFDTHTHLNVEEFAGREAEEIALAAEMGVIQMNIVGFDKPTIE
                     RALELVDEYEQLYATIGWHPTEAGTYTEEVEAYLLDKLKHPKVVALGEIGLDYHWMTA
                     PKEVQEQVFRRQIRLSKDLDLPFVVHTRDALEDTYEIIKSEGVGPRGGIMHSFSGTLE
                     WAEKFVDLGMTISFSGVVTFKKATDLQEAAKELPLDKMLVETDAPYLAPVPKRGRENK
                     TAYTRYVVDFIADLRGMTTEELAVATTANAERIFGLDSK"
     gene            complement(34621..35373)
                     /locus_tag="ACL29Z_000556"
     CDS             complement(34621..35373)
                     /locus_tag="ACL29Z_000556"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001099757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1542 domain-containing protein"
                     /protein_id="HGR0068910.1"
                     /translation="MCPVIILFYYKVEVAGDGTATITFPDGSVVTILGKDTVQQSAKG
                     ESVTQEVTPEYKLETTPGGDKGGNTGSSDANVNEGGGSQAGGSAHTGSQNSAQSQASK
                     QLATEKESAKNAIEKAAKDKQDEIKGAPLSDKEKAELLARVEAEKQAALKEIENAKTM
                     EDVKEAETIGVQAIAMVTVPKRLVAPNAAPKTTSAPQATAGTMQDVTYQSPAGKQLPN
                     TGSASSAALASLGLVVATSGFALLGRKTRRRK"
     gene            complement(35549..35683)
                     /gene="rpmH"
                     /locus_tag="ACL29Z_000557"
     CDS             complement(35549..35683)
                     /gene="rpmH"
                     /locus_tag="ACL29Z_000557"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000831903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0000315 - organellar large ribosomal
                     subunit [Evidence IEA];
                     GO_component: GO:0022625 - cytosolic large ribosomal
                     subunit [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L34"
                     /protein_id="HGR0068911.1"
                     /translation="MKRTYQPSKLRRARKHGFRNRMSTKNGRRVLAARRRKGRKVLAA
                     "
     gene            complement(35828..37042)
                     /locus_tag="ACL29Z_000558"
     CDS             complement(35828..37042)
                     /locus_tag="ACL29Z_000558"
                     /EC_number="2.6.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011836593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA];
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA];
                     GO_process: GO:0009058 - biosynthetic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HGR0068912.1"
                     /translation="MKEYNKSSKLEHVAYDIRGPVLEEAMRMRANGEKILRLNTGNPA
                     EFGFTAPDEVIHDLIMNARDSEGYSDSKGIFSARKAIMQYCQLKKFPNVDIDDIYLGN
                     GVSELIVMSMQGLLDNGDEVLVPMPDYPLWTAAVSLAGGNAVHYICDEAVEWYPDIDD
                     IKSKITSNTKAIVLINPNNPTGALYPKELLLEIIEIARQNDLIIFADEIYDRMVMDGH
                     VHTPVASLAPDVFCVSMNGLSKSHRIAGFRVGWMVLSGPKTHVKGYIEGLNMLSNMRL
                     CSNVLAQQVVQTSLGGHQSVDELLLPGGRIYEQRNFIYNAIQDIPGLSAVKPKAGLYI
                     FPKIDRNMYRIDDDEQFVLDFLKQEKVLLVHGRGFNWQEPDHFRIVYLPRVDELAQIQ
                     EKMTRFLKQYRR"
     gene            complement(37198..37492)
                     /locus_tag="ACL29Z_000559"
                     /pseudo
     CDS             complement(37198..37492)
                     /locus_tag="ACL29Z_000559"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009014348.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            37654..38106
                     /locus_tag="ACL29Z_000560"
     CDS             37654..38106
                     /locus_tag="ACL29Z_000560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000079155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="universal stress protein"
                     /protein_id="HGR0068913.1"
                     /translation="MAQRYQNIMVAIDGSKEADLAFVKGVHSALRNDAKLTIAHVIDT
                     RALQSVSTFDAEVYEELQVDAESLMKEYEKRAKDAGVADVHIVIEMGNPKTLLARTIP
                     DAEEVDLILVGATGLNAFERLLVGSSSEYILRHAKVDLLVVREQEKTL"
     gene            complement(38141..39529)
                     /locus_tag="ACL29Z_000561"
     CDS             complement(38141..39529)
                     /locus_tag="ACL29Z_000561"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000453140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HGR0068914.1"
                     /translation="MEVKAVFFDIDGTLVNNRKSVLKSTKDAIKIVKEQGVLVGVATG
                     RGPFFVKELMDDLDLDFAVTYNGQYIFSKDRVLFTSPISKLHLRHLISYAKKEGTEIA
                     LGTKDAMLGSKIMSFGLGSFSQRISRFVPSVLTRTVSQSFNRMVSKVVPQKEEDLLHL
                     MNQPIYQVLMLMTPEESEKAAADFEDLKLTRSNPFASDVINQGNSKLEGIRRVGKEYG
                     FDLNQVMAFGDSDNDLEMLAGVGMSVAMGNGSSSVKEAAKHITTSNQQDGIHKALEHF
                     GVLSSEKVFVSRDYHFNKVKTFHHMMDERTQEEPRAWDLEGATHRAGFKIEELVEFVR
                     SASPSEEDFGQAVSQLHQALDKAAGKVAKKTPAQQDLIGQVDALIDTLYFTYGSFVLM
                     GVDPERIFDIVHQANMGKIFPDGKAHFDPVTHKILKPDNWEEKYAPEPAIKKELQRQL
                     KAYERHKERNKS"
     gene            39595..40557
                     /locus_tag="ACL29Z_000562"
     CDS             39595..40557
                     /locus_tag="ACL29Z_000562"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="asparaginase"
                     /protein_id="HGR0068915.1"
                     /translation="MPKKILVLHTGGTISMQADASGAVVTSSDNPMNHVSNPLEGIQV
                     HALDFFNLPSPHIKPKHMLVLYQKIKEEADNYDGVVITHGTDTLEETAYFLDTMEVPH
                     MPIVLTGAMRSSNELGSDGVYNYLSALRVASDDRAADKGVLVVMNDEIHAAKYVTKTH
                     TTNVSTFQTPTHGPLGLIMKQEILYFKTAEPRVRFDLDHIQGLVPIISAYAGMTDELI
                     DMLDLEHLDGLIIQAFGAGNIPKETAQKLESLLQKGIPVALVSRCFNGIAEPVYAYQG
                     GGVQLQKAGVFFVKELNAQKARLKLLIALNAGLTGQALKDYMEG"
     gene            complement(40763..41773)
                     /gene="ccpA"
                     /locus_tag="ACL29Z_000563"
     CDS             complement(40763..41773)
                     /gene="ccpA"
                     /locus_tag="ACL29Z_000563"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000990602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0001228 - DNA-binding transcription
                     activator activity, RNA polymerase II-specific [Evidence
                     IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="catabolite control protein A"
                     /protein_id="HGR0068916.1"
                     /translation="MNADDTVTIYDVAREAGVSMATVSRVVNGNKNVKENTRKKVLEV
                     IDRLDYRPNAVARGLASKKTTTVGVVIPNITNGYFSSLAKGIDDIAEMYKYNIVLANS
                     DEDNEKEVSVVNTLFSKQVDGIIYMGYHLTDKIRSEFSRSRTPIVLAGTVDVEHQLPS
                     VNIDYKQATIDAVSYLAKENERIAFVSGPLVDDINGKVRLVGYKETLKKAGITYSEGL
                     VFESKYSYDDGYALAERLISSNATAAVVTGDELAAGVLNGLADKGVSVPEDFEIITSD
                     DSQISRFTRPNLTTIAQPLYDLGAISMRMLTKIMHKEELEEREVLLPHGLTERSSTRK
                     RK"
     gene            complement(42198..42797)
                     /locus_tag="ACL29Z_000564"
     CDS             complement(42198..42797)
                     /locus_tag="ACL29Z_000564"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HGR0068917.1"
                     /translation="MKVLVAEDQSMLRDAMCQLLTLQPDVESVLQAKNGQEAIQLLEK
                     ESVDIAILDVEMPVKTGLEVLEWIRSERLETKVVVVTTFKRAGYFERAVKAGVDAYVL
                     KERSVADLMQTLHTVLEGRKEYSPELMEVVMTRPNPLTEQEIAVLKGIARGLSNQEIA
                     DQLYLSNGTIRNYVTNILSKLDAGNRTEAANIAKESGWL"
     gene            complement(42799..43896)
                     /locus_tag="ACL29Z_000565"
     CDS             complement(42799..43896)
                     /locus_tag="ACL29Z_000565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004258104.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HGR0068918.1"
                     /translation="MLERLKSIHYMFWTSLIFMLFPILPVVIGELPAWHLLVDILFVV
                     TYLGVLITKNQRLSWLFWGLMLVYVAGNTAFVAGNYIWFFFFLSNLLIYHFGVRSLKS
                     LHVWTFLLAQVLVVGRLLIFQRIEVEFLVYMLVILTFVDLMTLGSVRIRLVEDLKEAQ
                     VKQNTQINLLLAENERNRIGQDLHDSLGHTFAMLSVKTDLALQLFQMQAYPQVEKELR
                     EIQQISKESMREVRTIVENLKSRTLTSELETVKKMLEIAGIEVETDNQLDTASLTQEL
                     ESMASMILLELVTNIIKHAKASKAYLKLERTEKELILTVSDDGCGFAFLKGDELHTVR
                     DRVFPFSGEVSVISQKHPTEVQVRLPYKERN"
     gene            complement(43896..44633)
                     /locus_tag="ACL29Z_000566"
     CDS             complement(43896..44633)
                     /locus_tag="ACL29Z_000566"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004249339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HGR0068919.1"
                     /translation="MKRWIALNKIEFLLTKRQLVYYLLSVGMPTAFYLFFSGIYQETP
                     GGPANFMRDYLISMTAFSMMSTAMFSFPAVLHTDKINNWQKTLRHSPVNMVEYYLSKI
                     TSMLVDYLVSILVVFSVGHFVRGVDMPLVKWVGAAILLIVGSIAFVALGLTLTLLPTS
                     QLMSVVGNLLYLGLAVLGGLWMPISLFPDWMQAIGKCLPTYQLMELLKTFLNEGGINL
                     SATVYLLVFSAVLFGLTIYLQGHKENA"
     gene            complement(44635..45519)
                     /locus_tag="ACL29Z_000567"
     CDS             complement(44635..45519)
                     /locus_tag="ACL29Z_000567"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000219360.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGR0068920.1"
                     /translation="MTVVKVEKLSKKIKDKEILRNISFEINDGECVALIGPNGAGKTT
                     LLDCLLGDKLVTSGQVSIQGLPVTSSKLDYTRAYLPQENVIVQKLKVKELIAFFQRIY
                     PNPLSNQEIDQLLQFVKQQKEQLAEKLSGGQKRLFSFVLTLIGRPKIVFLDEPTASMD
                     TSTRQRFWEIVQELKAQGVTILYSSHYIEEVEHTADRILLLNKGELIRDTTPLAMRSE
                     EIEKHFILPIAYKEVVEQSNLVENWTLKQDSLQVVTREADAFWELLAQAGCRMQEIEV
                     NNRSLLDTIFEETQKGDD"
     gene            complement(45506..45700)
                     /locus_tag="ACL29Z_000568"
     CDS             complement(45506..45700)
                     /locus_tag="ACL29Z_000568"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000820182.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0068921.1"
                     /translation="MKRGIIYFFIGLSLLVWLVEMFTDWFDQALLRQFIRGALGFGFM
                     IFVVFLMGMEWLKGESHDGG"
     gene            complement(45697..45903)
                     /locus_tag="ACL29Z_000569"
     CDS             complement(45697..45903)
                     /locus_tag="ACL29Z_000569"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000503440.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0068922.1"
                     /translation="MGEEEMRNKMIIAVSLVVAGVMTYLMFSGLDEDFYHFPWKVFAG
                     FGIMSWLVREGLKLVRDVKKEFEE"
BASE COUNT        13378 a        10757 c         8781 g        13569 t
ORIGIN      
        1 attaatattg aggtaacttt ttcttgataa aggaagaaat aatggagagg aagttagaat
       61 gaaaaaattc gacaattata ttattgagaa gccttgcgat tctaattcag ataaactgca
      121 aaaaatctta ataattgaaa gtttggtaga tgatattttg caattttctc tcagaatcaa
      181 taatagtgta ggagagattt tcctcctaca accgttttaa aagaaaacta tctttattcc
      241 atgttatttt gaggaagata ttgtgaaagt caaagatgat gataaagttg agtggaattt
      301 gttagaattt caaaaattta gagcattttt ggcttagtaa tctgtgttga aggctcaaaa
      361 cctatggtaa aaaagtagct ttgaaaacgt attgcctcca aagatttagt taaataatga
      421 tttaacacaa aaagaaatta ttgaagttct ggaaagatgt tgtttcagta ttgagaaaag
      481 gtgggaaaaa cttgcgattt tcacagagaa aggaagaaaa agtatagaaa tatagtcaat
      541 tgaaacaaga acaggataaa agaacctttt gtgccatatt tttctccttt cgctttacaa
      601 ttggcttgaa cacctttatt gtatcgcgtt tggagttttt ttggtataac cttcgacgcg
      661 cacccgcata gcgggtgttt ttttgtctcg cacctaacgg agcgagacga actaatagtc
      721 acttaatcaa aaaacgcacc atatcaaaaa ctaaaaagtt tgatatcatg cgtcatgtct
      781 taaactaatt gactatactt tctattcaaa tgagctttta accaattgat tgagccaatc
      841 cactcttaaa accaaagagc aatttctcgc ttagctgact cttctgaatc tgaaccatgt
      901 acaacatttt ggataacctc attttctcca gcagcttttg caaagtcacc tcgaatagtg
      961 cctggtaaag cttcttctgg acgagttgca cccatcatgg tccgccaagt ttcgattact
     1021 ttgggaccag aaatgacacc cacaagaact ggacctgaag tcatgaattc acgaatcggt
     1081 aggtaaaaac tctgaccaac caagtcctga tagtgctggt caatcaactc ttctgaaacc
     1141 tgtgaacgaa actccaattt ttcgattgta aatccacgtt gttcgatgcg ctttaacact
     1201 tcacccacta gccctctttt tacaccatct ggtttgatga taaagaatgt ttgttccata
     1261 cccgtctcct ttgtcagctt ctttctttta ttttaccaca tttcgtggaa aaatggagaa
     1321 agttttcaga agagagaatg agagaaccct cgggttctct cattctctct tattctactg
     1381 tttcttccac agtttcaacg gcagtatcca caactacttc tgttgtttct tcatttcctt
     1441 cttcctctac tggaggatta aggtattctt cttcgttgac agcatgtggt tcaaggttac
     1501 ggtaacgggc cataccagta ccagctggga tgatcttacc gatgataaca ttttctttaa
     1561 gtccaaggag atggtctttc ttaccacgga tagctgcgtc agtaaggaca cgagttgttt
     1621 cttggaagga agctgctgac aagaaactgt ttgtttcaag tgaggctttg gtaattccca
     1681 taaggactgg gcgacctgtc gctggaactc cacctgcgat aaggacatct ttgttggcat
     1741 ctgtaaagtc attgatatcc atgagggtac ccatgagaag atctgtatca cctggatcca
     1801 tgacacggac tttacggatc atttgacgaa ccattacctc gatgtgtttg tcaccgattt
     1861 ctaccccttg gctacggtaa actttttgta cttcaccgag aaggtacgtt tcaactgaca
     1921 agacatcacg aactgcaagg agacgttttg gttggataga accttctgtc agagcagcac
     1981 cacgcgctac ttggccccca acttcgacac gcatacgagc tgtaaatgga acgacatatt
     2041 caccttcgcc agtttcaccc ttaacaaaga ctttcttggt acgagttgat gcatcttctt
     2101 cgatagcagt aacttgtcct ttaacctctg tgataaccgc ttccccttta ggattacggg
     2161 cttcaaagat ttcttggaca cgaggaagac cctgagtgat atcggtattt gaggcaaccc
     2221 cacctgtgtg gaaggtacgc attgtaagct gtgtaccagg ttccccgata gattgggcag
     2281 caattgtacc aactgcttca ccaacttcaa ccgcatcacc agtcgccaag ttgataccgt
     2341 aacagtgacg gcagacaccg tgacgagtgt tacatgtaaa tacagaacgg atagtcactt
     2401 cttccacacc agcattgaca atttcacgcg ccttgtcttc tgtaatcaat tcatttggac
     2461 caataatcac tgcaccagtt tctggatgtt taacagtttt cttagtgtaa cgaccgttga
     2521 gacgctcttc gagagactcg atcatctctt ttccttctgc gatagaacgg atcaagagac
     2581 cacggtcagt tccacagtcg tcctcacgga tgataacgtc ttgggcaacg tcgaccaaac
     2641 gacgagtcaa gtaacctgag tcggctgtct taagggccgt atcggtcata cctttacgag
     2701 caccgtgagt tgagaagaac atttccaata ccgacaaacc ttcgcggaag tttgaaagga
     2761 ttggcaattc catgatacgt ccattcggag cagccatcag accacgcata ccggcaagct
     2821 gtgagaagtt tgagatgtta ccacgggctc cagagtccat catcataacg attgggttct
     2881 taggatcttg gttggcaatc aagcgtttct caagtttttc acgggcagca cgccattcag
     2941 ctgtaacagc attgtaacgc tcgtcgtctg tgatcatacc acgacggaat tgtttggtga
     3001 tttgttcgac acgtttgtgt gattcttcaa tgatttcagt cttgtcatca acgactggga
     3061 tatcggcaat acccactgtc aatcctgcaa gagttgagtg gtggtaaccg aggttcttca
     3121 tgcggtcaag tagggcagaa gtttctgtcg tacggaaacg tttgaagatt tcagcgatga
     3181 tatttccaag gtttttcttc ttgaatggag ggttgagctc aagattgctg atagcttcct
     3241 tgatatctcc accaagtggc aagaagtatt tagctggaac accttctgtc aagttggcat
     3301 tgtttggttc ttgcaagtat ggtagcccct ctggcatgat atcgttgaag agaattttac
     3361 caactgttgt aagcaagacc ttatgtcttt gctcttctgt ccaaggcttg ttgaggctgt
     3421 ctgttgcgat accaacacgt gagtggaggt gaacataacc attgcggtaa gccataaccg
     3481 cttcgtcacg gtctttgaag accattcctt caccttcgcg accagcttct tccatggtca
     3541 agtagtagtt acccaaaacc atgtcctgag atggagtaac taccggtttc ccatctttcg
     3601 ggttcaagat gtgctcagca gctagcatga ggatacgagc ttctgcttgt gcttcttctg
     3661 aaagtggtac gtggatggcc atttggtccc cgtcaaagtc agcattgtag gcttcacaga
     3721 caagtgggtg caagcgaaga gccttaccat caattaagac tggctcgaag gcttggatac
     3781 ccaaacggtg aagggtcggt gcgcggttca aaagcactgg gtgttcttta atcacttctt
     3841 caaggatatc ccagatacgc tcatctccgc gttccaccaa gcgtttagct gctttgacgt
     3901 tttgcacgat atcacgggca acgatttcac gcatgacaaa tggtttaaag agttcaatcg
     3961 ccatttcacg tggcacacca cattggtaca tcttaagagt tggaccaacg gcgataacgg
     4021 aacgtcctga gaagtcaaca cgtttaccga gcaagttttg acggaagcgt ccttgtttac
     4081 ctttaagcat gtggctcaat gatttcaatg gacggctacc tggtcctgtg attggacgac
     4141 cacgacgacc attgtcaatc aaagcgtcaa ctgcttcttg aagcatacgc ttctcatttt
     4201 gaacgatgat acctggtgca tttaactcaa gcaaacgagc caaacggttg ttacggttga
     4261 taacacggcg gtaaaggtca ttcaagtcag atgaggcaaa acggccacca tccaactgca
     4321 acattggacg aagatctggt gggataaccg gaaggatgtt aagaatcatc cattcaggtt
     4381 tgtttccaga cttgtaaaag gcatccaaaa catccaaacg acggatggct ttgacacgct
     4441 tttgtccagt agctgttttc aattcttctt tgagttcagc aatttctttt tcaagatcta
     4501 cttgcttcaa aaggtcttgg atggcttccg cacccatctt ggcaacaaat gaaccataac
     4561 catattcacg caagcgctct cggtattcgc gctctgtcat gatagacttg tgctcaagtg
     4621 gtgtatcctt aggatcaatc accacataag ccgcaaagta gataacttcc tcgagggcac
     4681 gagggctcat atcaagggtc aagcccatac ggcttggaat ccccttgaag taccagatgt
     4741 gagatacagg agctttcaat tcgatatgtc ccatacgctc acgacgaact ttcgtacgcg
     4801 ttacttcaac cccacagcgg tcacaaacaa ttcctctgta acgaatgcgt ttgtacttac
     4861 cacaagcaca ttcccagtct tttgtaggac caaagatcac ttcatcaaag agtccttcac
     4921 gttctggttt caaggtacga taattgattg tttcaggttt tttgacttct ccataagacc
     4981 atgaacggac tttacttgga gaagctaggg tgatttgcat acttttaaaa cgatttacat
     5041 caaccactat ttcttccctt tctattctaa gtgaactgct tattcttgtt cagcagcttc
     5101 ttctgttgct tccgcttttg ttgctttctc agcttcttca gcttcaaagg ctgctttagc
     5161 ctcttgggct gctttttcgc gggctttttc aaggtcatct acgtggatga catcttcgtc
     5221 cattccttca tccaagtcgc gaagttccac ttcttggtca tcttcgtcta ggacacgcat
     5281 gtcaagacca agagattgca attctttgac aagaactcgg aaggattctg gaacacctgg
     5341 ttttggaatt ggtttgcctt ttgtaatagc ttcataggct ttcaaacgtc cgttgatatc
     5401 gtccgacttg taagtcaaga tttcttgaag gacatttgac gcaccgtagg cttcaagagc
     5461 ccaaacctcc atctcaccga aacgttgtcc accaaactga gccttacctc cgagtggttg
     5521 ttgggtaaca gttgagtatg gtccgactga acgcgcgtgc aatttatcat caaccatgtg
     5581 gtggagtttg atcatgtaca tgactccgac agaaacacgg ttatcaaacg gttcaccagt
     5641 acgtccatcg taaaggatcg ttttggcatc gctatccata cctgcttctt taacagttga
     5701 ccaaagatct tcagaacttg ctccatcaaa gactggtgta gcgatgtgaa taccaagagt
     5761 acgagctgcc ataccaaggt gaagctccat aacctgaccg atattcatac gtgatggtac
     5821 cccaagtggg ttcaacatga tgtcgactgg agttccgtct ggaaggtaag gcatgtcttc
     5881 tacaggaacg atacgagaga caaccccttt gtttccgtga cgtccggcca ttttatctcc
     5941 gaccttaatc ttacgttttt gagcgatgta aacacgaacc aacatgttaa cacctgattg
     6001 caactcatct ccatttacac gtgtaaagat cttaacatca cgaacgacac catcggcacc
     6061 gtgtggtaca cgaagagaag tatcacgcac ttcacgagac ttgtctccaa agatagcgtg
     6121 caagagacgt tcttcagctg aaagatcttt ctcaccctta ggtgttactt tacctacaag
     6181 aatatcacct tctttaacct cagcaccaat acggataatc cccatttcgt caaggtcttt
     6241 gagggcatct tcaccaacgt ttggaatttc gcgagtgatt tcttcaggcc caagctttgt
     6301 atcgcgcgtt tctgattcgt attcttcaag gtgaacagat gtgtagacat cgtccttcac
     6361 caagcgttcg ctcatgataa cggcatcctc gaagttgtaa ccttcccaag tcatgtaggc
     6421 aacgattggg ttttgtccaa gcgccatttc tccattttcc atagaaggtc cgtcagcgat
     6481 gaaatcgcct ttttcaacga catcaccaac ttttacgaga gtgcgttggt tgtaagcagt
     6541 acctgagttt gaacgacgga atttttggat gtggtaaaca tccaatgaac catcttcacg
     6601 acgaacttct accttgtcag catctgcgta agtaacttta ccatcatact gagcaatcac
     6661 agccgcacca gaatcgtggg ctgcttggta ttccatacca gtaccaacgt aaggtgcctg
     6721 aggattaatc aatggcacag cctgacgttg catattggct cccatgaggg cacggttgga
     6781 gtcatcgttt tccaagaaag gaatacatgc tgtcgcaacg gcaactacct gttttggtga
     6841 aacgtccatg tagtcaacaa tattagctgg atactcttgg ttgacccctt ggtgacgtcc
     6901 catgacaatc ttctcagcaa aggttccatc ttcattcaga cgagagttag cctgagctac
     6961 agtatattca tcttcttcat cagctgtcaa ccaaacaatt tcgttcgtga caacacctgt
     7021 ttcacggtca accttacggt atggtgtttg aacaaaacca tatttgttca agtgtccata
     7081 agatgacaag ttattgatca aaccgatgtt aggtccttca ggtgtctcga ttggacacat
     7141 acgaccatag tgagtgtagt gcacgtcacg tacttcatat ccagcacggt cacgagtcaa
     7201 accaccaggt cctaaggctg acaaacggcg tttgtgagac aactcagaaa gcgggttgtg
     7261 ttggtccatg aactgtgaca actgtgatga accaaagaat tctttaactg cagctgttac
     7321 aggacggata ttgataattt gttgtggtgt caagacttca ttgtcctgaa cagacatacg
     7381 ttcacggaca ttacgttcca tacgagaaag tcccaaacgt acttggttgg caagcaattc
     7441 accaaccgca cggatacgac gatttccaag gtggtcgata tcatctacac ggccaagtcc
     7501 ttcagccaag ttgaggaagt agctcatctc agcaaggata tctgcaggag tcaccgtacg
     7561 aaccttgtca tctgggttag cattaccaat gatcgttacg acgcgatctg gatcagttgg
     7621 agcaataacc ttgaattttt gaagaacaac aggctcagtc acaacggctg catcgtttgg
     7681 gatgtagaca atcttgttca agtcgccatc caaatggctt tcaatgcttt caatcacgct
     7741 acgagtcata atcgtaccag cttctaccaa gatttctcca gtttcagggt ctaccaatgg
     7801 ctctgcaatg gtttggttga gcaaacgtgt tttaacattg agttttttat tgattttgta
     7861 acgaccaact gctgccaagt cataacgacg tgggtcaaag aagcgagcta caagcaagct
     7921 acgtgagctt tcagccgtct taggctcacc tggacgaagg cgttcgtaaa tttctttcaa
     7981 ggcttcgtct gtacgagagt ccattggatt cttgtggata tctttttcaa cagtgttgcg
     8041 aaccaattcg ctgtcaccaa agatatcaaa gatttcatca tcacctgaga aaccaagagc
     8101 acgaaccaag gttgtaaatg gaatcttacg agtacggtcg atacgagtgt aggtgatatc
     8161 ttttgagtcg ctttcaagtt ccaaccaagc tccacggtta gggataacag ttgaaccata
     8221 gcccacctta ccatttttgt ctactttgtc gttaaagtaa acacctggtg agcggaccaa
     8281 ctgagaaacg ataatacgtt caccaccatt gatgatgaaa gtacccattt ctgtcatgat
     8341 tgggaaatca ccaaagaaaa cttcttgggt cttgatttcg cttgtttctt tattgatcaa
     8401 acggaaggtt acaaaaattg gtgctgagta gctagcatcg tggatacgag cttcttctag
     8461 cgtatatttt ggttccttga tttcatatcc aacaaattcc aactccattg tgtctgtgaa
     8521 gtttgaaatt ggcaatacat cttcaaacac ttccttaaga ccgtggtcta ggaaagcttt
     8581 gaatgagtca gtttgaattt caatcaaatt tggtaagtca agaacttctt tgattcttga
     8641 aaaactacga cgggtacgat gtttcccgta ttgaacgtca tgtcctgcca agatgattct
     8701 cctttgtaaa taagttccaa gccttgtcaa tcaggctttt ctaatcgtca tatggttgta
     8761 aaccccttat caccgtgtcc tcttgatgaa ttttcagaat ctttaagcct ctgttacaaa
     8821 tgctcaaaat cttgaaaaaa agcacaaaaa gagcagctaa atctgacttt ttcagaagat
     8881 ttaactgctg tgagccttgt ctggacaata tttcagacaa aacctacgac aaatgattac
     8941 ccatattata ccctatttag ctagattttt caaggggttt cagtaggttt ttggtaaatt
     9001 ttttcccata gaaaacttgg catcacattc gaatcacgct atggtacaaa aaactgaaaa
     9061 aactattgac tgaaaatcat tttcaaggta taataataaa cgttaaggcg gtatagccaa
     9121 gtggtaaggc acggctctgc aaaagcttga tcgtcggttc aaatccgtct accgccttct
     9181 ataacttgat ttatcaggtt tcaaatgaac agaaagccca atttgaaggg ctttttttat
     9241 tttccctcga ataaatacgt ataactttaa aaacttttgg agcgagtttg tggcagagtt
     9301 ctttccatgg cataattccc ttttgaaatc aattgaaaaa agcttcgtca cgcctggtga
     9361 caaaagcctc tagtttattc tgtttcttct tctatttcga cttctgtgat ttggactttt
     9421 accttggtaa cacgtccatt cttcacttta tcattggtta agataaactg tttgttttgg
     9481 ctaaccaatt catagctgag tttctcagtc gttggaatag ttcccactcc tgtcaaataa
     9541 taaccagcga tggtatcaac gtcatcactt tccagttcaa catcaaagta attattgaaa
     9601 tcattgaggg tcatagttcc ttgaacaatg taggtatcct cgccaatctg atgaacatct
     9661 attgctgctt tgtccgtttc atcatcaatt tcaccaacaa tttcctctaa gaggtcttcc
     9721 aaagtcacca aaccagccat accaccgtat tcatccagca agattgccat ttgtctttgg
     9781 gtatttcgca gttcttttag caagtcatcc acaaaaatag tttcaggtac aaaaagtgga
     9841 tcttgcaaaa ttctcttcca aacaatattg tcaaaaccgt ccacaaagcc tgccttaagg
     9901 agactcttgg tgtgaatgat tccaattaca ttgtccttat ccccatcata aaccgggata
     9961 cgagaataat tttgttttaa aatactttgg ataatggctt gactatcatc ctgaatatcc
    10021 accataaagg catccgttcg aggaaccata acctctcgtg ccatcagttc atcgagcgaa
    10081 aagacacctt gtagcatctc aatctcatca gcatccaatg tttcttcact atttgtcagc
    10141 atataggcaa tttcatcacg ggtcatcttt tcatccgcat catcgaatga cataggagtc
    10201 aaatggctca agaaattggt cgaagcagct aaaagccaaa caaaaggact gactagtttt
    10261 ccaatcccaa tgataaccgg cgctgtacga attgccaagg catcctttag attaagagcg
    10321 attctcttag gatataattc cccaaaaacg atggaaatat aggtcaaaaa tgccaaggat
    10381 agaaaagttg ccacggcttg tgctgtttcg ccattcccaa gccaagaggc aatcacacgt
    10441 cctagagtat tagttaaact cgcccctgat aagattgtaa tcagggtgat tcctacctga
    10501 atggttgata aaaagtggtt aggattttct agtaccttca gcaggcggat gtagcgtctg
    10561 tctccttctt ccgccttttg ttcaactcgg gcacgattaa gagaaaccat ggccatttct
    10621 gtggctgaga aaaaggcatt taataccgtc aagataaaca ataaaacaaa ttgtagcaac
    10681 aaattctgac tacttgggtc ttccatagtt cttctcctaa aatagtatct tatcctttat
    10741 tatatcacaa aatttaatcc aatacatatt attttttctt accgtaactt ctcaaagtaa
    10801 cttccatctc tctcccaaaa ctggaagtta gttttagaag ttgctatttt ttcttagtac
    10861 ctgttctagc cctgcttaaa ctagtaaaaa gaactcctac atccataagt gacataggag
    10921 tttaggctta tcttttactg agttacagtt acttctccag ttcggtaatc cagttgaagt
    10981 cccttttgaa cattgggaac tagaacattg aattccaatt ctccatccga agacttggct
    11041 tcaatctgtg aagctgaagg aactaaatcc tcgtttgaag cgtagtaaag ggttacacgg
    11101 taacggacac gcttgttttg gtccaaggct ttacgcacct tgctttcata gtagttttga
    11161 ccagtcgaat actcggcttg tgcctgattt gcccaggctg tctgaacagc aatgttttta
    11221 ggattgcttg ttgaggcatc aaaaccatcc aaaccaccga ttaaggcata gcctaacaaa
    11281 tgacctctat cgactgcatg ggtataagag ccctttagat tcttgacctg atgccaacct
    11341 ggaggagtcc aagaagttga accattccca gtttctttac gattcttgta ctgacgagtg
    11401 gccttagaca agagggcatt agctacggtt ggaacagttt ccttgcccac tgtctttgtt
    11461 ttattgtcag cgtagggctt acttgaaacc ttggcatcta gatttgtttt attaccattg
    11521 acgataaaag cacctgagcc attccactcc agactcccct ttatttgact cttgactgcg
    11581 tctgttaaga cactctctgc caatgcttga ctaggagctt cagacgcttg ttttttctga
    11641 ctaagattgg ttttgggact attaggtgcc gacggcatct gcttgatata atagctccct
    11701 gtagacaaaa gcaataacac tagcagtccg attagtgtct gtcttgtttt tttgttcata
    11761 tttctcctta tctttagaaa aaggctggtt ctccagccta atttcctgta aatttatgaa
    11821 tcaattcctg ccattttgct ggagacagga tagcccatgg atcttgaccc ttgcccaaga
    11881 ttccataacc taccattaaa ccgattccta gagccagagt acctaaaatc agtactatga
    11941 tgactaaaag taaacgcttg actacgtagc ttgatttctt attcatcttc atcacttgcc
    12001 tcaatccgct gaatcttagc acctagctgc gccaacttct catggaaacc gtagtaacct
    12061 ctatccaagt gaaccaattt accgaccaca gtttctccct gtgctaccaa acctgtcaaa
    12121 atcaaggctg cactggcacg aaggtcagtt gaaagaactt ctgctccctg caaaggctgt
    12181 ccaccaacaa tacgagctgt atcacggata atctcagaat gcaagcccat gcggcgcatc
    12241 tcttctaggt gttggaaacg attttcgaaa actgtctcca ccatggttga ttcgcctttt
    12301 gcaactgtca tcaaggctgt aaattgagcc tgcatatctg ttggaaatcc tgggtggggc
    12361 aaggttttca catgaacagc ttttagattt tctagttgag aacgaacacg aattccttcg
    12421 tcttcttcaa ttacttcaac acccatttca agtaacttgg caatcaaggg acggttgtgc
    12481 tcccagacag cgtctcgaat caagacatca ccaccagtca tggcagcagc taccataaag
    12541 gttcctgctt cgatacggtc ttggactaca ttgtgagtcg taccatgaag tttctcaaca
    12601 ccagtaatgg ttatagtctc tgtaccagca cctttgacct tggctcccat ttcattaagg
    12661 agaatggcta agtcaacaat ctcaggctca cgcgcagcat tctcaatcac tgtcacccca
    12721 tcagccagag tcgctgccat catcaagttc tgcgttgcac caacacttgg aaagtccata
    12781 tagatatgag cgccatgcaa gcgttctgcc ttggcttcga tgtaaccagc tgtctgacta
    12841 atcttaaccc ccatagcttc cagacctttc aaatgaagat caataggacg gctaccaatc
    12901 gtacaaccac ctggcatgga taccttggca tgacccacac gggcaaggat tggccctaat
    12961 acaacgatgg aggcgcgcat cttgctgaca tacttgtaag gggcttcctc agtgatgtcg
    13021 ccagtagcat ccaccttgac aagatgagct tcctcatcaa agtcaacctt ggcattcaaa
    13081 ccaccaacta cctgattcat aataaagaca tccgacaaaa tcggaacatt ctgcaagacg
    13141 gtctttcctt cacttgctag aatagtcgct gccaacaagg gtaagactgc attttttgct
    13201 ccctcgatcg tcacgcttcc taccagacga ttatcgccac cttgaaccac aattttatcc
    13261 atactcgttt cctttactct tgatttcata ataatcctct aagcgcttct tgccacaaat
    13321 gatacaggct aataaagaaa gaactcagga tgtagcctat gacaatgcta aaaaaggcta
    13381 ctaataaacg aacttttctt gtattatcat ctgtcacttt taaaaccttc tcccatctaa
    13441 caagatcctt taaaaggtaa aaactcacat aaataaagaa catatgacta cttagagtga
    13501 ataataattg aaccatttga ctattatacc atcttctctg tttgtgcgct agtttggaaa
    13561 cttcactcaa aaattaggga ttgtttttca agtaatcaat cgcatcttgt agggttttaa
    13621 cgggcacgat tttcatatcc gtcttgattg ttttagccgc ttctagggct gtttggtagt
    13681 tgtttttcgc gtccggatgc gccttttgtt cttcttcgct aacagggtta tcaggagcaa
    13741 agaaaatagc agcacctgcc ctagccgaag ctacaacctt cttatcaata cctccaatgt
    13801 ctcccacatt accatcgcgg tcaatggtac ctgtaccggc aacaatacga ccattacgaa
    13861 gatctgggtg agctatttga gtatagatag ctagactaaa catgagacca gcacttggac
    13921 cgccaatacc agctgttgaa aagctaattg ggacattgct gattacctct gtacggtcaa
    13981 tcaagccgat tccaattcca tttttgccat tttccaaggt gatgattttt ccttctgcag
    14041 acttggtttg cccatcctct tcataggtga ccttgacgga atcccctaat ttttgagaac
    14101 tgacgtaatc aatcaagtct ttggaactat caaaggtctg atcattgact gctgtgactg
    14161 tatcagagat attgagaatc tctttaaagg ttgaattatc cgtcacattc aaaacataaa
    14221 ctccaaagta cttgagttcg atatccttac cagctgtttt tagtccttga tacttggcca
    14281 tattttgcga tgtttgcatg tagaattgat tgattcgcat aaattcaaca tcggaagaac
    14341 cacctgtagt ctcctgagca ctacgaatat ctgtaaaagg tgtcaaccaa gcataaatca
    14401 tatgagctaa agtggcatgt tgaacaccaa ccgtaacgaa ttgataggca ccagcttcct
    14461 tatcttctgt gtcatttact ttaaggactt ggcgaatatc ttccgaacca cctggaacct
    14521 ctatataata aggcaagggc actacaaatg ccaagaaagt cacaatcaag gccgcaatga
    14581 cgtataaggg ccatctaatc ttttttttca tttcttattt cctccaaaat actctcggga
    14641 acatggcagg caatatcctg accaaacttc aaaagctctc gaacacctga tgaactgata
    14701 tagagatgtt caggccggct atgtaaataa atagtctcta tatcagaaga cagctgatga
    14761 ttgtagtaat caaaactagc ttcatattgc aaatccgccg cattcctcaa cccccgtact
    14821 aggaaagtag cccccagtct ttttgcaaca tcgaccacca attcatcatg agaagccacg
    14881 acttcaacat tttccaaatg tcccaaagcc ttttctagcc cccgtttacg attttcaaga
    14941 gggagaaatc cttgtttgtg gggattaaaa aaaataccca cataaagctt atcaaaaagt
    15001 ctgctcgccc gttcaatgat atccagatgc ccatttgtca tcggatcaaa tgagcctgtg
    15061 aataagccaa tcttatctga catagactgt caccttacta attccataaa tcttttcctt
    15121 ccagataccc agacaggcaa tctcttctgg aagttcaacg gccttatccg tctcgcacac
    15181 aaccataaca tcttcagaaa aaagctctct cttagccatt ttttcaatat ctgctacgat
    15241 ttgttccttg gcatagggag ggtctaagaa aacgaggtca aattccccag atacctgttc
    15301 caatgccctc tctgcatcca tcttgaggag ttgaaatttt ccaacttcct tggtcatctg
    15361 gatattttca gccacgatgg tctgagcctt acggtctcgc tccaccaaaa cagcactgga
    15421 catgccacgc gatactgctt cgatagataa accaccacta cctgcataaa ggtccaagac
    15481 tcgtccccct tcaaagtagg gaccaatcat gttaaaaatg gctcccctaa ccttatccga
    15541 agtaggtctt gttgtcttgc cttctagtgt cttgagggga cgtcccccat agattcctga
    15601 tacgattttc atactgttta ttataccaaa ttatagacaa aaagagaaag aaaaccgaac
    15661 cttgcggttc gattctctac aaaatatttt cgtaagtatc gcggacttct tgaggccaaa
    15721 cacttgtttg cacttctccg atgtgtctct tgcgaagtag gaacatggcc atacgagatt
    15781 gtccaattcc tccaccgatt gtcaatggga ataggccatt caacaaagac ttgtgccatt
    15841 ccaattccaa gcggtcttca tcacctgtaa tttccacctg acgtctaaga gtttcttcat
    15901 ctacacgaat tcccatagaa gacaactcaa aggctccacc taaagactca ttccagacaa
    15961 gaatatcacc atttagaccc ttgtagccat tctcagactc gcttgtccag tcatcatagt
    16021 ctggtgcacg tccatcgtgc ggtttaccat ctggcaactc gccaccgata ccaatcaaaa
    16081 agacggctcc aaattcttta caaatcgcat tttcacgttc tttaggtgtc aagtctgggt
    16141 agcgttctac caattcttct gtatggataa aggtgatttg ttttggcaag atagactcga
    16201 tgtcatagcg ggcttcaaca gctagctcag tcaagcgaat agccttataa atcttctcaa
    16261 ctgtttcttt tagataaacg atgttacgct taccatttgg gataaccttc tcccagtccc
    16321 actggtcaac ataaacagag tgggttgcat ccaaggaatc ctcatctgga cgaagggctt
    16381 tcatgtggac aaagagaccc tctccttcac caaagccaaa acgagccaag gtgtggcgtt
    16441 tccatttagc aagtgagtgc accacttcat aagtagcatc agggatttgg agaaccttga
    16501 ccgatactgg attttccaca ccagacaggt tgtcctgcat tccgtcaccg accttactca
    16561 agataggacc ttgaacttcg acaacttcta gcttatcttt caaatactgg gtaaaagtat
    16621 ttttgacaaa ggaaatttct tcttgttgat ggataaaact tttcttcata gacaactcct
    16681 caaaaattta ataaacgtat tatacaccta tttccaagaa aagaaaagag aaaatttaaa
    16741 aaaatcagtg tcactcaaaa cactgatttc atagaccttt tagtcattgc gaccaaagat
    16801 acgtagaata cttaggaaaa gattgataaa atcaagatag atgctgagag ccattgacac
    16861 cacccagcct gtcgctacac gaccttgtga ttgttcatag gcgaggcgaa tcttttggtt
    16921 atcccaagca atcaaccctg aaaaaaccaa aaccatggct acgctaatca tataatcaaa
    16981 gaagccacta gccaagaaaa tattgactac catagcaatc agtaaaccaa tgagagctgc
    17041 catcattgct cgaccaatcc cactcaagtc tttcttggta aaaataccaa ctgccgccat
    17101 gacaaagaag agaagggcgc tcgatacaaa ggcagataaa actgtacccg gagtatagaa
    17161 agccaccaca aaactaaggg taaagccgtt taaaacggag taaagtaaaa atactggaag
    17221 agcagctgga ctatttcttg aagccatgct actggcaacg aaaaccaaag ccaactccgc
    17281 aaaagtagca atggtcaacc agagacgccc ctgcatcaac aagtaaacca actgagactg
    17341 aaagaccgtc aacataaggc ctgataccaa agcagatagt ccgattccca gaccaacaaa
    17401 ggcataaacc ttagcgtaaa attgattgag acctgcacgg tcatgtataa tagtgtgatt
    17461 catccttttc tccttttctg tgaacatctt tccttgatta taacaaaaaa agttaaaatt
    17521 agcttaaatg gaagattaaa ataccggttg caactgcaac attcaaactc tcggcctgcc
    17581 ccttcatgct aatatggacc aactggtctg cactttcagc cataagggga ctaattcctt
    17641 gaccctcatt tcccataact agtacaaaat tttctataga aggcagttct ctgtaatcaa
    17701 cagaatcttt agatagggtt gttgctagca ctgggatagc taccttttta gtttcgtcaa
    17761 gaagcgcttg actagtcatc cggtaaatgg gcagatggaa atgactacct tgcatggaac
    17821 gtagggtttt gagactgtag atgtctgccg acttatctga aacaatcact cctgtaaaac
    17881 ctgctgcatc cgcagttcga atgatagttc ctacattacc aggatcttgc acatcttcca
    17941 aaaacaagaa cttgccctga ctcaaatcag cttgtcctac ttcttctttt tgaaccacgg
    18001 caacaattcc ctgtggagtc tgagaatccg ccaaatctag caaaatatcc tctgaaatcc
    18061 agacagtttg cggaaaagca gctaactgat ttcgataatt ttctagggca aagattttct
    18121 caatcgtcac tccagcttgg acagcttctt caaacaagtg ccagccttca atcaaatagg
    18181 cagacttgcg gtattttttt tggtgtaatt tcttggcatt ttttaccaca gaattggctt
    18241 ttgaggttat aatagtcata gaaatattat aacacaatca aaggggtttg gtatgcaaaa
    18301 ggttagaatg attgcccaag gtagggtgca gggagtcggc tttcgttggg gtgtttatag
    18361 cctggccctt gaaatcggtg gcatcacagg tcgggtatgg aataacgacg atggcacagt
    18421 ggaaatctta gcccaagcag actcatctgc tatcatggca aaatttatcc aagaaatccg
    18481 aaaaggaccg acaccttttt caaaagtaag ctacttagat gtcaaactaa gcaactttcc
    18541 tccctactct gactttaaaa tcgcaaatta ggtctccaga actattgtat attttgtaaa
    18601 aaaacagtag aatagaaagg tataattttt aaagaaggaa taaaaacagt gaaatctatt
    18661 aaacgttttg cattctcggc tatgggagtg gctatgttgc ttgtcttgac tggctgtgtc
    18721 aatgtcgata aaaccacagg tcagccaaca ggatttattt ggaatacgat cggagcgcct
    18781 atggctgaag ccatcaagta cttcgctact gataaaggtc taggctttgg tgtcgctatc
    18841 attatcgtaa ccattatcgt acgcttgatt atcttaccac ttggtatcta ccaatcatgg
    18901 aaggcaacgc ttcactctga aaagatgaac gctctcaagc atgtccttga gccacaccaa
    18961 acacgtctca aagaagcaac tactcaagaa gaaaaactcg aagcccaaca agccctcttt
    19021 gccgctcaaa aagagcacgg catcagcatg tttggtggtg taggatgttt ccctatcctc
    19081 cttcaaatgc ctttcttctc tgctatctac tttgctgccc aacatactga aggggttgct
    19141 caagcaagct acctaggcat tcctctaggt tctccaagta tgattttggt tgcctgtgct
    19201 ggtgtccttt actatcttca atcgctcctt tcacttcacg gagtagaaga tgaaatgcaa
    19261 agagaacaaa tcaagaaaat gatttacatg agcccactca tgatcgtcgt cttctccctc
    19321 ttctcaccag ctagtgtcac actttactgg gttgtcggtg gtttcatgat gattctccaa
    19381 cagtttatcg tcaactatat cgttcgtcca aaacttcgca aaaaagtccg tgaagaacta
    19441 gccaagaacc caccaaaagc aagtgctttc tctaaaccaa gtggacgaaa agacgttacc
    19501 cctgaacaac caactgctat cacaagcaag aaaaaacaca aaaatcgcaa cgctggaaaa
    19561 caacgttcga gataagaaga aaaaggctta gctgatttgc taagtctttt tgcaaatcaa
    19621 aagcccgatg tttccatcag gtttcttttc tatccatgta cacgtttcat ataatcttga
    19681 taactttcgg tatccatgag ttttttagcg ttcttgacgc gatctgctgt tggtggtttg
    19741 actccttcga gggaatatgg aattccaagt tcacgccact tgaactcacc catggtgtga
    19801 taaggtagaa tttcaaactt atcaacattt ttgagggtct tgacgaactt accaagttca
    19861 atcaagtcat catctctgtc tgtcaatcct ggaactagca cgtggcgaat ccagacaggt
    19921 tttccaatat ctgatagata ctgggcacaa gccaagatat ttttattagt ttggctagtg
    19981 acaatcttgt gctgttcttc gttgatttcc ttgatatcca aaagaaccaa gtcagtgaca
    20041 gccatgagtt tgtcaaactt ctcaaggtaa cgtggtttat tacggaaagg aagagcacag
    20101 gtatccaagg tacagtggat tccttgttcc ttagccttgg tgaagagagc aatcaggaaa
    20161 tcaatctgca agagagcttc tcctccactg actgtaatcc cacccttatt tccccagaaa
    20221 ccacggtagc gcaaggcctc tgtcaagaca tcatctaccg tccgttcacg tgacttattg
    20281 gactccatag cccaagtgtc tgggttgtgg caatactggc aacgcatgtg acagccctgc
    20341 aaaaagacaa taaagcgaat accaggccca tctactgacc caaagctttc tgtcgaatgc
    20401 accattcctg tcacttgtcc ataatcaatt gtttcttcag acatatcgtt accttccttg
    20461 aaaacgtttt atagttttat tatatcacga cttgaaggaa aaacaagatt tttgcctatt
    20521 ttttagaaag caatctgttt ttcaatttca ttttcaatct attatcagat tattcttcaa
    20581 aatcgaagcc atataaggtt gcaaaatagt cctcagggcg ctctgcacgg cggatttgac
    20641 gggctttacc ttcttcggta tagaggattt ccgcagaacg taatttggca ttatactggt
    20701 agcccattga aaatccgtgg gcacctgtat catgaattac cagcaaatca ccgatttctg
    20761 tatgaggcag ttcgcgattg actgcaaatt tatcattgtt ttcacagagt gaaccaacca
    20821 catctaccgc ttcagctggt ccatctggat gggtcacgtt gctaatatga tggtaagctc
    20881 cgtacatagc tggacgcatg aggttgactg ctgaggcatc cacacctaga taggtacggt
    20941 aggtttcctt cttatgagtc actcttgtga ctagagcacc gtgaggtgcc agcataaaac
    21001 gacccaattc ggtgaaaatc ttgacctgac caagacctgc tgacgtaaga acttcttcat
    21061 acaccttacg aactccctca ccaatcaagg cgatatcgtt cggctcctgg tctggacgat
    21121 aattaacacc aataccgcca gaaagattga taaagtctag cgaaatgccc aacttttcct
    21181 tgatttcaac agccagttca aagagctgac gagccaactc tggataatag agatgggtca
    21241 cggtattgga cgctaggaag gagtgaatcc caaaagtctt ggctcctttt tccttcaaga
    21301 tagcaaaggc ttcaaagagc tggtccttgg tcatgccaaa cttagcctcc ccaggattgt
    21361 ccataatgtc tgtccccagt tcaaaaacgc ctccaggatt ataacgacaa gagatgattt
    21421 ctggaatgcc tgctactctc tccagatgtt caatatcttc aaaggcatcc aagttaatgg
    21481 tcgcacccaa ttcacgtgca taggcgtatt ccttgtctgg cgtgttgttg gaagagaaca
    21541 taatctcaga acccagaaag tccagtttat ggctcatcaa aagctctaca taactagagc
    21601 agtccacacc acaaccttct tcttggagaa ttttcaaaat agctggagtt ggagtagcct
    21661 taactgcaaa atattcctta aagcccttgt tccacgaaaa agcttggtta acggctcttg
    21721 ccttctcacg aatccccttc tcatcataca agtgaaaggg agtcgggaac tcggcaacaa
    21781 tcgcttctaa ctcttctcta ttgataaatg gtgttttcat aagcttcctt ctattctgtt
    21841 tgcaaagaaa ggctgggaca atcgttccaa cctttagttc tatctcttat ttatcttcgt
    21901 caaagatatt gccaacctca acatcgatgg cttggttctt gacatcaata ttggttacct
    21961 tcaagagtga cttgtagtca aactgctttt cacgttcttc ttgggcattg tccgcaaaga
    22021 ccgctacacc tgccagttct gagtcgaact cgcgcaagag actaatcata ccattgactg
    22081 ttccgccacc tttcaagaag tcatccacaa tcaagacacg gctgcctgcc ttaagactac
    22141 gttttgaaag gaacattttc tcgatacggt caccacttga acctgaaaca tagttgacgc
    22201 taacagttga accttcggta attttcaggt cacggcgcac aatgacaaaa gagacattga
    22261 ggacattggc aactgcattt gcaagtggca cacccttagt tgctacggtc ataaccgcgt
    22321 caattttttg gtccataaag cttttggcaa taatacgacc aatatgtttc aagatggctg
    22381 gtgtgctaag caaatcagac agatagatat aaccacctgg caagatacgg tcactttctg
    22441 acaacttggt acgcaagtct tcaaccattt ccttagcatc ctgactcgaa atagacggtg
    22501 tgaagatgac acctccgcca gccccagtca ctgtctggat atgaccgatt tcaatttcct
    22561 caaaggcgcg tttgataatg acgatatctt ctgagatgga tgatttagca gactcatact
    22621 tttcagcaaa agtattgaga ctagttagtt tataaggatt attaatcaaa tagttggaaa
    22681 tgacaaccat ccgatcactt cttcttaatt tcatttctat ttcctattcc atttttattc
    22741 aaaaaatcaa aaagcaaact agaaagctgg tcgctggtgg ttcaaaacac tgttttgaga
    22801 ttgtcgatag aactgacaaa ccctgtaata tacctgcata tatacatacg acaaagcgat
    22861 actaccctag tttgaagaga ttttcgaaga gtattcattt ttgtctttta cttattatac
    22921 catattcaca taaaaaaacg aacattctta tcctaaaaaa tgctcatttt tcttaaatta
    22981 tcaatctaaa tctggtttat agaaggaacg attatccata gcgaagattt tattggacat
    23041 ctctccttta tccaccaaag ccagagctgt tgacatcatc atcatgcttg catccagatt
    23101 gtcaatcata tggataatct ctgcctccat aatacgtgga cggactggac ttccatattc
    23161 aagcaagccg tggtgactga ggatgacatg acgaagcaaa acgacttctt ccttggtatc
    23221 atcgatgccg agttccataa ctgtcttggt aatttcgcta tcaatgagag cgatatgtcc
    23281 aagaagatta cctcgcactg tgtactctgt ctggtctggc cccgtcaact cgataacctt
    23341 agctaagtca tgcagcataa tccccgcata gagtaagctc ttattgagct gaggataaac
    23401 ttcgctaata gcgtctgcca aacgtaccat ggtcgccgta tgataagcca agcccgtttc
    23461 aaaggcatgg tggttggtct tggcagctgg ataggagtag aattccttat catacttggt
    23521 gtagagattt cggacaatcc gttgccagac aggattttca attttgaaaa tcatttgcga
    23581 catgtagtca cgaatttcct tgacatcaac tggtgacttg accttgaaat cagctgggtc
    23641 attgggttca ccagcttgag gcaggcggag agtaatttga ttgacttgag gggtattgtt
    23701 ataaacttct cggcgtcctt tcatgtggac aaccttacct gcggtaaagg cctcaatgtt
    23761 atgaggttgg gcatcccaga gcttcccatc aatctcgcca ctatcatctt ggaaggtaaa
    23821 ggctaggtag tttttcccag ctcgagtttg cctcaggtca gctgatttga ttaggtaaaa
    23881 gccttcaaat aactcatctt ttttcatgtg actaatcttc atattcttcc tcattttctt
    23941 gaaaatagag tagatcaagc gcaggctcac cttctgacaa ctcaatgtga cggagcgtcc
    24001 gctcgatagc tatggtacga cggtttaata attcatcaat attgccagag gcatgttgga
    24061 gatgtttttg tgccttgacc agaataccac caaacttgcc aaactcggtc ttgacactgg
    24121 caagagtctt gctgatatgg tcggcactct tttggatatt aagggtcttg aaaccaactg
    24181 atagggagtt aagaagggct gatagggtac ttggtcctgc aacaataatc tgttcttccc
    24241 gtctcaaatc atcaaagaag accggattgc gcacaatctc tgaataaaga ccttctgtcg
    24301 gaacaaacaa gattccaaag ttggttgtcc gaggcggtgc tatgtacttg ctcttgatat
    24361 ccttggcaaa gcgcttgacg cttgctagga gtgacttacg acagcgttca atctcatcct
    24421 tgtcacctgt ctcataggct tcttccaagc ggtaataatc tgccagtgga aacttagagt
    24481 caattggaag atagacgtat tcttggtcgc cttgtccggg taacttgatg gcatactcca
    24541 ctcgttcact agagttttca accgttgcgt attctcgttc gtactgggca ggtgtcatga
    24601 tgtcttcaat aatttgcccc agttgcaatt ctcccagaat ccctcgcgtc ttggttccag
    24661 agagaacctt gttaagagct ccgacatcac gggcaactgt ctgcatttct ccaagaccac
    24721 gattgacaga ctccagttgt ttagaaactg tctcaaagga agcctgtaag cgtgtctgca
    24781 aggtcttttc tagtttttcc tcgaccgtct ggcgcatttg ttccaaacgt tgctcatttg
    24841 attcctgcaa ggcttggaga cgttggtctg tcttgtctct agtttggagg agattatctg
    24901 tcatttcttg acggacttgg gtcaggcctt ggtgcaattc aatccgcact tcttgcaaac
    24961 ggtcgctgac agccacttcc aaatcttttt ggtctaactg gctggcttgt ctggcttggt
    25021 caaagcggta atccaactgg tctgacaaat gatctgcctg atcctccaag ctcttactta
    25081 agtgtttctc ctgcctatcc tgtctttgcc aaatcagaaa gagaccagct aggttggcaa
    25141 ttaataatag aataagtaaa ctttccatcc tacctcctgt ccttgctatg cagtacgacc
    25201 acataaccat ctgggcaagt caccgacact tccctatcta tatattcgtt agaagcgtac
    25261 acttttttaa agaaaaaatt ctcctctgtc aactcatact tagctccaag aatagtcagc
    25321 tggctatccc gaactggcat aaaggctaga tagtcgtagt ctgaacgagg ttctagctga
    25381 ctggtccctt ctgaacaata ggcaatcaaa ttttgcccat cctcaatttc tatttgacgc
    25441 atatagggtg ccaacttagg attgctaggt agaaagacat tggccaacat atggtcaata
    25501 cggccaccca aggcaccgaa aatagtgacc tcagcctgag gattttgttc aaagatggtt
    25561 aagagagcca attccagatc tgtatcatcc ttttctggtc gggcttggac aaaatgctgg
    25621 gcacgttttt gaatcacctg tcgctcttct tccgtcacag aatcaaaatc tccgactgct
    25681 agagcaagag gtaagtcttc ttccaagacc cagagcgagc ctcgatccac cccaacaaaa
    25741 gcatcaaaat ctgtccgata atgaccgcgg tttccgcctg caaaaactgc aaccctagtc
    25801 cagttgtttt ctgagagttt gtactcgctc attgacttct cccttaaaga cataggaacc
    25861 tgctacaaaa acagtcgcac cagcttcttt ggcttgagca atagtttggt catcaatccc
    25921 accatccact tcgatttcaa agttcaaacc tttttcctca cgaagagcaa ccaactcacg
    25981 aaccttatcc atggtttctg gcagaaaggc ttgcccacca aaacctggat taaccgtcat
    26041 gactaaaact tggtcaacta gatgaaggac gtgcttgatg gcttcaactg gtgtgccagg
    26101 attgataacg actgaaggct taactccgag tgaacgaatt ttttggaggg cgccatgaat
    26161 atgaggtgtt gcttctacat ggatactgat gatgtctgca cctgcacgcg caaaatcttc
    26221 cagatgatgc tcagggtttg acaccatcaa gtggcaatcg aaaaccatct tactatgagg
    26281 acgaaggctc tcgaccacac ctgcaccaaa actgatttgc ggtacaaaat gactgtccat
    26341 gatatcgata tgggcatatt ctgccccagt tgcttctaga cgtttgattt cacgttcaaa
    26401 gttggcataa tctgctgcca gaattgacgg agcaatcttg tattgagaca taggtttctc
    26461 cttattttgg aatttttttg ctgacttttt tataggtttc tctacgattt tcaatttcac
    26521 taaggaattg caggtaatta tcaaaacgga aggttgcaat aacaccctct tcaacagctg
    26581 gtttgacggc acaagacggc tcatgggtat gggtacaagt acggaactta caatctcggc
    26641 taacagtagc aatctctggg aaagcctgat tgaggtcttc agcccttgat acttcatagt
    26701 ccagagatga aaagcctggt gtatctgcga ttttaccccc gttgagattg taaaaactaa
    26761 cagctcgagt ggtatggcga ccgcgaccta gactgtctga aatttctccc gtttcaagat
    26821 tgaggtctgg tacgagttta ttgagaagag ttgacttccc aacacctgtc tgccccataa
    26881 agaccgtaac cttgcctgtt aacaaagaca ggagttcctc tttactggtc acaaagtcat
    26941 agccgatgtc accataggtc tgccggtaaa aatccagttc tcccctatct tccaacaaat
    27001 ccattttgga aatatagaca atgggatgga tgcccttgtg ctccaaaaga accaagaaac
    27061 gatccagcaa attgctgtta aaatcaggtt ccttgacgga catgattact acagcttgat
    27121 cgatattgac aataggcgga cgaaccagac tgtttttccg ttcgtgaatt tttaggatat
    27181 agccttctga attttcctcg gcagagaaat ctacccagtc cccaacataa ggggtatggc
    27241 cttttttacg gaaattccca cgcgcgcgtg tttgataaac ctggccatca ctctccacat
    27301 agtagaaacc tgccaaggct ttaatgattt gtccctgcat cttagagtcc ttgcccttta
    27361 agtgcgtctg ctagaccggc aaattctgcc aagctgagag cttccccacg cacacttggt
    27421 gacaagcctg cctggtccaa agccttggtc agcttgtcct tgacctcttc agtcttacca
    27481 aagtaacctg tcaagttatt ccacaaggtc ttacggcgat ggataaaact agccttggaa
    27541 accttaaaga agaagttctc atcttccact gctacagctg gctctggacg gcgcaccatt
    27601 ttcaagatgg ctgaatccac atttggcgct ggcacaaaga ccgtacgagg cacgataaag
    27661 gcaaccttgg ctgtcatgta atactgcacg gcgatagaca agctaccgta agccttggtg
    27721 ttaggctggg ctgaaatgcg gtccgctact tctttctgca tcatgaccac aaactcacta
    27781 aaaggaatgc cactctcaat caagtgcatg agaataggcg tcgtgatgta gtaaggcaaa
    27841 ttagccacta ccttgattgg caggttagga tttttaaaat tttggatatg ttgcgccaaa
    27901 tcaaccttga gaatatcttc gttaactaca gtcacattat caaaatcacg cagggtatct
    27961 gccaaaattg gcaccaaacg gtggtcaatc tcaaaagcca tgacttgggc tgcacgctca
    28021 gccagaaact ccgtcaaggc accaatacct ggcccgattt cgatgacatt gacctggtca
    28081 tcaatttcag ccgtatccac aattttttga aggatattgg tatccgtcag gaaattttgc
    28141 ccgaaggact ttttaaaggt aaaaccgtga cgctccagca ctgccttggt cacgctataa
    28201 tctgcaattc tcatctattc tcttttctat tatctgttac tactattgta acacattccc
    28261 cttgtatttt gggaatgaaa atcataccaa aaaactatct ttcctcatga agaaagatag
    28321 tcttggaaat ctttaaaagt ggccttaaca gttctctcga aacatgcgtt caaaaaaatc
    28381 agcttcttga taacttcgat tttcgggtag ggtcaaatcc acatcctcct ccacatcatc
    28441 cactgtcagt tcaaccgtct gaggtaaatt tttcaaacga taatgctttt gcctttgccc
    28501 ttcaatacta gcaaaatcaa gcaaatagcc atgcactcgg atttgaacca aaaggagatg
    28561 attggtcata ttttccatga tgaggatatc ttctaaacca cctctggcac taggataatc
    28621 agataccctg cgaatacgga ttttttcaca catgagcaag tttcctcata tcaatgattt
    28681 catcagcctt attccagact aggggattat gggtcgcaat gatgataatt cgattttcat
    28741 ctttcaaatc caccaagaga ttcataacct cctctgaatt ttcaggatca agagctgctg
    28801 ttggttcatc tgccaaaatc aagggtggat ttttcaaaat agtcttagca agggcaactc
    28861 gttgggcctc tcccccagat aaagtataaa ttttttgttc taaatccaaa taccctagat
    28921 taactttttc taaagccccc acttgccttt ccaaacgttc tacttttgag attttctgac
    28981 caacaaaacc caaatccaaa ttttctttga ttgattggtt ttctaagagg ccaaaatttt
    29041 gaaagagata gcccatctga tctcgaaaat actcacgagt gggaatggtt tttaaatctt
    29101 tcccctgata gagaaccctt cctccatcta tcttttctag ctttcccaag atattcagca
    29161 gcgtcgtctt tccgcttcca ctctttccga ttaaggcata aaccttgccc ttctccagct
    29221 tgagattcaa accagagaaa atcgcgcggt cattaaattt cttttccaat ccttgaatat
    29281 caatcatctt attttccttt caatactgcc atgctaccag cttcttcttt tttgtcctgc
    29341 cttactaaaa tcaagagggc gttaagcgta aacaaagcta caactagagc gctaatcaaa
    29401 ccatctcttg tcaaaatact agataggact aggccaagca agagaactcc tccttgcgcc
    29461 agtaaatact tgccatgaag ctcatagatt gtcataccag caagacgttt aatcataagc
    29521 tcccgtctga actgctcaaa atagagaaga ttcatggaat caaataacaa gatagccgta
    29581 gacagggtca aaatcgtccc aataaggaga gagtaaaact ccacccgttt gtcatttagt
    29641 accttggcaa aaaatagctg gctttttacc aagtaagaaa ccttgtgata cagaccttgc
    29701 tcttttagag ctgtgatgct gtctccatat cgatctagtt tcaaggcact attagccgta
    29761 gttccccaca acatccctgc aacaggtctt gttccagtcg cttgcggcgt tagaactaca
    29821 ataatcggat cttttaggta ctggcgtgtt gtcttgtacc catcattata gaggaaacgt
    29881 tcctgtcctg tttctgtaaa agctagcctt acctgtggga ggtagtattt ctgactcgtc
    29941 acttctacac tttcagatga aaagttttgc aggtaatctg taaacaatcc ttggtagtag
    30001 gtagactgct ctcgcaagct ctcaggcaag atcagcccaa actctccctc agacaagttt
    30061 tgcatcttgt ccataaactc tgaagaaacg gtaatctttt cttctatcag atagcgtggt
    30121 gagacataga taacattccc tgacggtgtg tagtcactga gacgattgcc atctaggtcc
    30181 acttctgctc catctgagaa attgtcaaca ttgctcataa tataaaaaga gtctgtattg
    30241 gctaaccgtt cttcagtaaa tgtctgccac tcacgattat ccttacgcgt tccttcttca
    30301 tcggcaaatg cactagacca accaaaggat agacggtaac ggtctgagga ctggctccat
    30361 ttattgctag ctctctccat ttcctgcatt tcacggtagt ggggtaggag agctgtcgca
    30421 ctcgatccga ccaccaatac agctaagagt tgccccacca tcatcaatgt catcatacgt
    30481 ttgagaggga gtttcccttt caatagatcc accagactat tttcctgtaa accaagtaga
    30541 tagacgacac ttagtaaggt agaaatccct gccagggtca atccataaag tagaagagca
    30601 atgatgacca gttgcaccgt tgccataaac aaggcacctt gataccagag aatccccaat
    30661 cccaaaagac tggataccag cactgagcag ataagctgtc tcacatcttc taacactggt
    30721 ctgagagcaa ctccaaacaa gctctcacca gctattaagc gaatccctgc ctgacgaagg
    30781 gatttgatcc gataaatcag ggtcagactc ataaaggtca gcagaaaaat agctaaactc
    30841 agtagcacca taggggtggc cgtcaatagt aagactatcg aaaatggatc ttctccattc
    30901 gaaacaaagc cttgatagcc aagttctttc aaggtggtct gtaagctcac tccatccaaa
    30961 cttcctgaca caatcaagta agaccctaat aaatcactcg tttctgcact ctccttggag
    31021 gaaatggtca gaccttctgg aagctctccc tcaccataag tggcataggt aaagagtgtt
    31081 tctccagctt catttggctc aacgattcga cgggcgatga gactattatg ctctaccgcc
    31141 aagtgactca aagcctctgt cacctcttcg cgactagcta ctggttgatt tatcatcatt
    31201 cctgtcacat caacagaagg atagttacca aataaaatct cttctcgatg gtcaacggaa
    31261 gttatcacca tataaagcga taccaatacc attgaaatca aaataaataa acgtttcatc
    31321 atttcctcca aaaagttact tggtcactta gtgagaaggt gaccaagtaa agctaaacaa
    31381 tagggctata ccattctaaa cattatagta gaatgcaact ttctctcccc aagaagtacg
    31441 aatccatgca cgagaagtcc ctccagcacc agcatatccc ttgtcagatg aaccagtttt
    31501 tctgctaaca actgttgaac tatggtattt tgaagggtga tagtagtttg agtaagcacc
    31561 accgttacct gaaccataag tccaaacacc accttctggg tattgaacgg ctgcagaggc
    31621 aactgctaca cttccaccta atgttgctgc aatgctcgct acaagagcta attttttaac
    31681 tgtttgtttc atattgatac tcctctattt ttgattacaa gattgttgag ttacttgctc
    31741 ctctttccat tatcaacgtt gatactatta tattaccaaa tgatattcta aaattatttg
    31801 tttttctcta aattgtcaaa atagcaccct gaaatgaact tttatagtca ttatactcca
    31861 tctttatcac actatcaagg acatcaatgt ccttaaaatc taactatttc atattatttt
    31921 tagcttatat ctaaaaaaac agttctaaag acgaacttta gaactgtttt gatacgagga
    31981 caaggacatt tttgtcactg attcactatg tttataaata ttttttgaca tcctcttgcc
    32041 attcctctgt caatttcttt actagaaatc catctccaat tagcttcgca aatgttttag
    32101 aagactgata aaatgattca gctaaactaa aatctctttc tactcttaat gcttgcttcc
    32161 acaaaaacat aaatacaaga ggtttctttt gataatcttg agttttatcc ataatttctt
    32221 gtaaacacga tagataatca ttaaaacaat cagttactcc taccttttca agacaacaca
    32281 ttcctgaaat aagagtatct ctaattataa agtaattctc tatttgagtt accttcttct
    32341 gttccaaaag aaagagcatt agcttttcga tttgatttat aaatttggca agatcttttc
    32401 taatgagcat ttgataaaaa aacaaacgaa tcaacaacat atcatttatt gaataagctt
    32461 ctttttctat aatctgaggc atatgttcct caagtattaa ctctgcatat tcaggccttc
    32521 tagttctaga agtatccaaa cacgcctgca atacttcaca tgctaattgt tcttctttag
    32581 gaagattatc aaagtatgtt ttataaatct cttccaaaca cgcttccttc ttatcgtact
    32641 cctcttcttt accatagatt ggttcacgta aaatctggta tttcaattct aaataagcag
    32701 aaggaagagc tgaaaaatcc ggcagaaggc tataaactgg aactcctagc cggcgagcaa
    32761 tataggctaa cttgggcaaa ctcggttgcg aagctccact ttcaattcgc gacagttgac
    32821 gaactgtcag ttcttgctca tctccacaaa aatctggacg actaattcct ttttctatcc
    32881 gaatctcttt aattttttga ccaattaaca tcagacgcct cctcttctac ctgcttcgaa
    32941 aaatactgtg aaacttaaaa aattgtaacg gctacatctt tcctactcat aagatttcat
    33001 agcttcttcc acttctgcca aagtaacccc aaacaactct aggcgtttga ggagttgctt
    33061 gccgttagaa tagccgattc ggagagtctc tccgagatat tctctacgct tacggctgtc
    33121 tgcccctgct agaaaaccaa ggcgaatcaa atcgctacga ctaatgtcaa actgactctc
    33181 atgttcaaat tgttctgtca cctgagctag agccgttttc aggtcttcat agctggcatg
    33241 ctcaattccc agagaacgcc ccttggtctt ggacttggga acagcttcat ctcgcttgag
    33301 aaaggcatgc tgaactgttg gaatggccgt cataatcatg cgccgaatcc gctccccatt
    33361 aaaatctggg tctgtaaaga caatgactcc atgacgttgg tgtagacgct gaatccgctc
    33421 tatgtcctgg tcattgatgg cagaacctcg agtctcatag gtctccacat cgaaataacg
    33481 cttgagattg accgtatcat cacgaccttc aaccacgata acttgggaaa ttctctcttt
    33541 cattacttgc tgtccaatcc aaaaatgcgt tctgcatttg cagtcgttgc taccgccagc
    33601 tcttctgtcg tcataccacg caagtcagcg ataaagtcga ccacatagcg agtataggct
    33661 gttttatttt cacgaccacg cttgggtaca ggtgctaagt aaggcgcatc tgtttctacc
    33721 aacatcttgt ccaaaggtaa ctctttagct gcttcttgga ggtcagttgc cttcttgaag
    33781 gtcaccactc ctgagaagga aatggtcata ccaagatcca caaacttctc tgcccactca
    33841 agcgtccctg aaaatgaatg catgatacca ccacgaggac caacgccctc actcttgata
    33901 atctcatagg tatcttccag cgcatcacgg gtatggacaa caaaaggcaa atccaagtcc
    33961 ttagatagcc gaatctgacg gcgaaaaacc tgctcctgca cctctttggg cgctgtcatc
    34021 caatggtaat ctaagccaat ttcacctaaa gccacaacct tgggatgttt taacttatcc
    34081 aacaagtaag cctcaacttc ctctgtataa gtaccagctt ctgtaggatg ccaaccaata
    34141 gtcgcataga gctgctcata ctcatctacc aactccaagg cacgctcaat cgtcggttta
    34201 tcaaaaccaa caatattcat ctgtatcaca cccatctcag cagccaaggc aatttcttct
    34261 gcctcacgac ctgcaaattc ttctacattc aagtgtgtat gtgtatcaaa aatcatctct
    34321 tctaacctcg ttttctatct tctattatac caaaaaagag gaggggcacc taatttttcg
    34381 gtttcccctc ctctcttcaa tagagagcta ttctgctatc ttttctatcc gatattgccc
    34441 atctcctatt ccacagttag agacagaaga gattggctac attgatagaa tattcctatt
    34501 cagctaaagt atgtgattat cttgggttct cacttttctc acccatcact aggattgatg
    34561 acttctcaaa atccccctta taatctaact ttaagtagag aatagaattt tctagctgtt
    34621 ctattttcta cgtctagtct ttcttcctag caaagcaaaa ccacttgttg ccaccactag
    34681 accaagacta gcaagtgctg cacttgatgc tgaacctgtg ttaggtaatt gtttgccagc
    34741 aggtgactgg taggtaacat cttgcattgt tcctgcagtt gcttgcggtg cacttgttgt
    34801 cttaggagca gcattaggag ccactagtct cttaggaact gtaaccatgg caatggcttg
    34861 cactccaatc gtttctgctt ccttcacatc ttccatagtt ttcgcatttt caatctcttt
    34921 gagagctgct tgtttttctg cttccactct tgctaaaagt tctgcttttt ctttatcaga
    34981 aagcggtgcg cctttgattt catcctgctt gtccttggct gctttttcaa tggcattttt
    35041 agctgattct ttttcagtag ctaattgctt agaagcttgt gattgagctg agttttgtga
    35101 acctgtgtga gctgatccac ccgcctggct accaccgcct tcattcacat tagcatctga
    35161 gcttccagta ttgcctccct tatctccacc tggtgtagtt tctagcttat actctggtgt
    35221 aacttcttga gttacagatt cacctttcgc agattgttga actgtatctt ttcctagaat
    35281 cgtcactact gaaccatctg ggaatgtgat tgttgctgta ccatctccag ctacttcaac
    35341 tttatagtaa aataaaataa taacaggaca aatcgatcag gacagtcaaa tcgatttcta
    35401 acaatgtttt agaaacagag gtgtactatt ctagtttcaa tctactataa catcgcttcc
    35461 gaatccattt gcatctactg aactttttta caaaaataaa aatcagtaga ctcgagttcc
    35521 tactgatttt tgatagaatt cgtttggatt atgcagccaa aactttgcgt cctttacgac
    35581 gacgagctgc caatacgcga cgaccatttt tagttgacat acggttacgg aatccgtgtt
    35641 tgcgcgcacg acgaagttta cttggttgat aagtacgttt cacgatgaat acctcctcat
    35701 agattttgta ttcgtttagc cggctataaa gtgatcagtt actaaacata ctttactatt
    35761 ctatctgatt ctttcacttt tgtcaatagc cctaggcaaa tgtttccagc tttttcgaat
    35821 gcaagcccta tctacgatac tgtttcaaga aacgagtcat cttttcttgg atttgggcta
    35881 actcatcaac acgaggaagg taaacgatac ggaagtggtc tggttcctgc cagttaaagc
    35941 ctcgaccatg aaccaagaga accttttcct gcttcaagaa atcaaggaca aactgctcat
    36001 catcatcgat acggtacata ttgcggtcga tttttgggaa gatatagagc cccgccttgg
    36061 gtttaacggc agacaaacct ggaatatctt gaatggcatt atagatgaaa tttctttgct
    36121 cgtagattcg tccaccagga agaagcaatt catcgactga ttggtgaccc cccaaggaag
    36181 tttgtacgac ttgttgggcc aaaacgttag agcaaaggcg catattggac agcatattga
    36241 gcccttcgat atagccctta acatgagtct tagggccaga caagaccatc caacccacac
    36301 ggaaacctgc tatgcggtgg gattttgaca gaccattcat gctgacacag aagacatctg
    36361 gtgccaagct cgccacaggc gtatgcacat gtccgtccat taccatgcgg tcatagattt
    36421 catccgcaaa gataatcaaa tcgttttgac gggcaatctc aataatctcc agcaagagtt
    36481 ccttaggata aagggctcca gttgggttat ttggattgat aaggacaatt gccttggtat
    36541 tggaagtgat ttttgacttg atatcgtcaa tatctgggta ccattccaca gcttcatcac
    36601 agatatagtg aacggcattt cctccagcta ggctgacagc cgccgtccat agaggatagt
    36661 ctggcattgg cactaagacc tcatccccat tgtccaaaag cccctgcatg gacatgacaa
    36721 tcaactcact gacaccattt ccaaggtaaa tatcatcaat atctacgttt gggaatttct
    36781 tcagctggca atactgcatg atggccttac gggctgagaa aatccctttg gagtcagaat
    36841 agccttcact atcacgcgca ttcataatca agtcatgaat gacctcgtct ggcgctgtaa
    36901 agccaaattc tgctggattt cctgtattca gacgtaaaat cttttctcca ttcgctcgca
    36961 tccgcatggc ttcttccaat acaggaccac ggatatcata agcaacatgc tctaacttac
    37021 tagacttgtt atattctttc atcttgtttc ctcaattcat caggatagta acattatacc
    37081 actagaaaga gaatgcgaca agtttactga aatgtgttac tagtttcgta tagaagaaaa
    37141 accttgctaa aggcgaggtt aagaacgtag agatagcagg tattttgcaa agacacatca
    37201 cataccaaaa gataaaccta gaaaaaagca agcctagaaa ggagtcataa agaagattaa
    37261 acatgaggaa aagcccccat atcatcaagt aatcccaacg cccacttcgt tttgcaacta
    37321 gaaataagat tagatggtag agtacatgaa aaactaaaaa tccaataaaa cttggataaa
    37381 gaagcggtac cagactctct aattgacaga tcatgatcac ttctaccaag actgaaacta
    37441 ggataattcc ataataaagg aaatttgatt tttgaaaaga gtttttcatc attctccctt
    37501 ccttcacttc tttcctgcta tcctttcttt tattttatca tatatttata tagagtttaa
    37561 gccctaatat tcttttgaaa aatacttttt ttgctttact tctatagtga aaaggtttac
    37621 aattatagta agaaaatttc aggaggtttc attatggcac aacgttacca aaatatcatg
    37681 gtcgcaatcg atggttctaa ggaagcggac ttggcttttg tcaagggagt tcattctgct
    37741 ctacgaaacg acgctaaact caccatcgca catgtcattg acacacgcgc tctccaaagc
    37801 gtatccacct ttgatgctga agtttacgaa gaactccaag tcgacgctga aagtctgatg
    37861 aaagagtacg aaaaacgtgc taaagatgct ggggtagcag atgttcatat cgtcattgaa
    37921 atgggaaatc caaagaccct gctagcacgt actattccag atgccgagga agtggacctc
    37981 atcctcgttg gcgcaactgg tctcaacgcc tttgaacgcc tcttggtcgg ctcttcatct
    38041 gaatacatac tccgccatgc taaggtcgat ttgctggttg tgagagaaca agaaaaaacc
    38101 ttataatcac aaagaaaagg agcccctagc tcctttttgt ttacgattta tttctctctt
    38161 tatggcgttc gtaagccttg agctggcgct gcagttcctt tttaatagca ggttctggag
    38221 catatttttc ttcccaatta tctggtttta agattttatg ggtcactgga tcaaaatgag
    38281 ccttgccatc tggaaaaatt ttccccatat tggcctgatg gacaatatca aaaatacgtt
    38341 ctgggtccac ccccatcaag acaaaactgc cgtaggtgaa gtaaagcgtg tcaatcaagg
    38401 catccacttg ccctatcaaa tcttgctgag caggtgtctt cttggctact ttacctgctg
    38461 ccttatcaag ggcctgatga agttgcgata cagcttgacc aaaatcttct tcagaaggac
    38521 tggctgatcg aacaaactcc accaattctt ctattttaaa accagcccta tgggttgcac
    38581 cctctaaatc ccaagctcga ggttcttctt gggttcgttc atccatcatg tggtggaagg
    38641 tcttgacctt attgaaatga tagtcacggc tgacaaaaac tttttctgaa gacaaaacac
    38701 caaaatgttc caaggccttg tggatcccat cttgttgatt gctagtggta atgtgcttgg
    38761 cagcttcctt gacactgcta ctaccatttc ccatagcgac cgacataccg acgccagcca
    38821 gcatttcaag gtcattatct gagtcaccaa aagccatgac ttggttgagg tcaaagccat
    38881 attctttccc aactcggcga atgccttcta atttagaatt tccctgattg atgacatccg
    38941 atgcaaaagg attgctacgt gtcaatttca agtcttcaaa atcagctgcc gccttctcag
    39001 attcttctgg tgtcatcagc atcaaaactt ggtaaatagg ttgattcatc aggtgaagca
    39061 ggtcctcttc cttttgggga acaaccttgc tgaccatgcg attaaaagac tgactcaccg
    39121 tccgagttaa aacagaggga acgaagcgac taattcgttg ggaaaaagaa cccagaccaa
    39181 aggacatgat tttagaaccc aacatggcat ccttggtccc taaggcaatc tccgtgccct
    39241 cttttttagc atagctaatt agatggcgca aatgtaactt ggaaataggg ctcgtgaaca
    39301 agactctgtc tttactaaag atatactggc cattataggt taccgcaaaa tccagatcca
    39361 aatcgtccat caattcctta acaaaaaaag gtcctcgccc tgtcgctacg ccaactagta
    39421 ccccttgttc tttgacaatc ttaatcgcat ccttagtgga tttcaaaaca ctcttgcgat
    39481 tgttgaccaa ggttccatcg atatcaaaaa aaacagcttt gacttccatc ctatcccaat
    39541 ctcccctttt gtgatacaat gattatacca catttcagaa agagtgagta aatcatgcct
    39601 aagaaaatcc ttgttttaca tacgggtgga actatttcca tgcaggccga tgcttctggc
    39661 gctgttgtga cgagttcaga taatcccatg aaccatgtgt ccaacccact tgaaggaatc
    39721 caagtccacg ccttggactt ttttaacctt ccaagtcccc atatcaaacc caaacatatg
    39781 ctggtcctct accagaaaat taaagaggaa gcagataact acgatggagt ggtgatcaca
    39841 cacggaaccg atactttaga ggaaacagcc tatttccttg ataccatgga agttccccat
    39901 atgcctatcg ttctaacagg agccatgcgt agctccaatg aactcggtag tgatggtgtt
    39961 tataattacc taagtgcttt acgagtggcc agcgatgaca gggctgctga caaaggagtt
    40021 ttggtcgtta tgaacgatga aatccacgct gccaagtatg tcaccaaaac acatacgact
    40081 aatgtcagca ccttccagac tccaacacat ggcccccttg gtctcatcat gaaacaggaa
    40141 atcctctact tcaaaacagc tgaacctcgt gttcgctttg accttgatca catacaaggt
    40201 ttagtcccta tcatctcggc ttatgctggt atgacagatg agctgattga tatgctggat
    40261 ttagaacact tggacggttt gattatccaa gccttcggag ctggtaatat tcccaaagaa
    40321 acggctcaaa aattagaaag ccttctgcaa aaaggaattc cagtcgctct ggtatcacga
    40381 tgctttaacg gtattgccga gcctgtttat gcctaccagg gtgggggcgt acagttgcaa
    40441 aaagcaggcg ttttctttgt taaagaactc aacgcccaaa aagctcgctt gaaactcctc
    40501 atcgccctca atgccggact aacaggacag gctttgaaag actatatgga aggctaatac
    40561 tcttcgaaaa tctctgcaaa ccacgtcacg tcgccttacc gtatgtatgg ttactgactt
    40621 cgtcagtttc atctacaacc tcaaaacagt gtgttgcgca gcctttaacc agccgcctag
    40681 tccgctctat ggtattcatt aagtcaacat ctcttgttta agagcacaaa atcaggaaat
    40741 cttctcgatt ccctgatttt ttctatttac gttttcgtgt tgagctacgt tctgtcaaac
    40801 catgaggtaa gagaacttca cgttcttcca actcttcctt atgcataatc ttggtcaaca
    40861 tacgcatact aatggcacca aggtcataaa gaggttgggc aatcgttgtc aagtttggac
    40921 gggtaaagcg tgagatttgt gaatcatcac tagtaataat ttcaaaatct tctggcacag
    40981 aaacaccctt atcagccaaa ccgttcaaga ctcctgctgc caactcatca cctgtcacaa
    41041 ctgctgcagt tgcatttgat gaaatcaaac gctctgctaa ggcgtaacca tcatcatagc
    41101 tatatttaga ttcaaatacc aaaccctcac tataagtgat tcctgctttt ttcaaggttt
    41161 ccttgtagcc aactaaacga accttaccat tgatgtcatc cactagcgga ccgctaacga
    41221 aagcaatacg ctcattttct ttagcaaggt aactcactgc atcaattgtt gcttgcttat
    41281 agtcaatatt gacacttggc aactggtgct caacatcgac agttcctgcg agaacaatcg
    41341 gagtacgtga acgcgaaaat tctgagcgaa ttttatctgt caagtgatac cccatataga
    41401 taatgccatc tacctgcttt gaaaagaggg tattgacaac agaaacttct ttctcgttat
    41461 cttcatcgct attagctagg acaatattgt acttgtacat ttctgcaata tcatcaatcc
    41521 ccttagccaa actcgaaaaa taaccattgg taatatttgg aatcacgaca ccgacagtgg
    41581 ttgtcttttt acttgcaaga ccacgcgcaa ctgcatttgg acgataatcc aaacgatcaa
    41641 ttacctctag cactttttta cgggtattct cttttacatt tttattgcca ttgaccacac
    41701 ggctgaccgt cgccatggaa acacctgctt cacgagcgac atcataaatg gttactgtat
    41761 catctgcatt cattcctttt cctgtccttt ctatctcaca cattctttta caagtagagg
    41821 tactgattga agctctatat ctacttacaa aagtgaagat gtgaaaattt cgttttcata
    41881 tttctactta ttccattcta tcactaattg taaacacttt caagtgtttt ttgaagattg
    41941 attgaaaaaa tttcatagaa aacctaggtt tagctccttg ctaccacctt agactaaaca
    42001 aaaaggagga aactaagccc tcctaaagtt atagtaaaat gaaataagaa caggataaat
    42061 cgatcaggac agtcaaatcg atttctaaca atgttttaga agtagaggtg tactattcta
    42121 gtttcaatct actataggta ttgttccatt cactaccgtc aattttagca catagtcttc
    42181 atgaaaatat tatatcatca taaccaacca gattcttttg cgatattagc tgcctctgtt
    42241 cgattaccag catccagttt tgaaagaata ttggtgacat agtttcgaat agttccgttt
    42301 gagaggtaaa gctgatctgc gatttcttgg ttggataagc cccgggcgat cccctttaag
    42361 acagcaatct cttgttctgt caacggattg ggacgggtca tcaccacttc catcaattca
    42421 ggcgaatact ccttgcgtcc ttcgaggacg gtgtgcaagg tttgcatgag gtctgcaacg
    42481 cttcgttcct ttaatacata agcatccact ccagccttga ccgcacgttc aaaataccca
    42541 gcacgcttga aggtcgtcac cacaaccacc tttgtttcaa gcctttctga tcgtatccac
    42601 tccaagactt caagacctgt cttaacaggc atttctacgt caaggatggc gatatctaca
    42661 gactcctttt ctaatagttg gattgcttct tgcccattct tggcttgaag gacagactcc
    42721 acatctggtt gaagcgtgag caattgacac atggcatctc gcaacatact ttgatcttct
    42781 gcgactaata ctttcatctt agtttctctc cttataaggt agtcgaactt gcacttccgt
    42841 tggatgtttc tgactgatta cacttacttc tcctgaaaat ggaaaaacac gatctcggac
    42901 tgtatggagc tcatctcctt ttagaaaagc aaagccgcag ccatcatcac ttactgttaa
    42961 aatgagttcc ttctctgtcc gttctaattt taagtaagct ttagacgctt tggcatgttt
    43021 gatgatattg gtcaccaact caagcaaaat catagaagcc attgactcca attcttgagt
    43081 aaggctagca gtatctagtt ggttatccgt ttccacctca attccagcaa tttctaacat
    43141 ctttttcaca gtctctagtt cggatgtcaa agttctagac ttaagatttt ccacaatggt
    43201 tcgaacttca cgcattgatt ctttgctaat ttgctgtatt tctcttaatt ccttttccac
    43261 ttgtggataa gcctgcattt gaaatagctg caaggctaga tctgtcttga cactaagcat
    43321 agcaaaggta tgtcccagac tatcatgcaa atcctgaccg atacgattgc gctcattttc
    43381 tgctagcaat agatttatct gggtattttg cttgacctga gcttctttca aatcctcgac
    43441 aaggcgaatt cgaaccgagc ccaaagtcat caaatcgaca aaagtaagaa ttacaagcat
    43501 atagactaga aactcaactt cgattctctg aaaaatcaaa agtcgcccca caacaaggac
    43561 ttgagcaagg agaaatgtcc atacatgtaa agactttaaa ctacgtacgc caaaatgata
    43621 aattaagaga ttggaaagga aaaagaaaaa ccagatataa ttcccagcaa caaaggcggt
    43681 attcccagct acatagacca gcatgagccc ccagaaaagc caagataggc gctggttctt
    43741 agttattaaa acacccaaat acgtcactac aaatagaata tcaaccaata aatgccaagc
    43801 aggaagctcc ccaatcacta caggtaggat gggaaaaagc ataaaaatca aactggtcca
    43861 aaacatatag tgtatgcttt tcagtctttc aagcattaag cattctcctt atgaccttga
    43921 aggtaaatag tcaaaccaaa taaaactgct gaaaaaacaa gtaaataaac tgtggctgat
    43981 agattgatgc caccctcgtt taagaaggtc ttgagcaact ccatcaactg ataagttggg
    44041 agacacttac cgatcgcttg catccagtct ggaaataaag agataggcat ccagagtccg
    44101 cctaaaacag ccaatcctag ataaagaaga ttgcccacaa cagacatcag ctgactagtt
    44161 ggtaagagag tcaaggtcaa gccaagggct acaaaagcaa tactccccac aatcagcaaa
    44221 atcgcagctc caacccattt tactagaggc atgtctacac ctcttacaaa gtgcccaact
    44281 gagaaaacca ccaagattga aaccaaataa tcaaccagca tacttgttat ctttgataga
    44341 taatattcta ccatatttac agggctatga cgtaatgttt tctgccagtt gttgatttta
    44401 tctgtatgta aaacagctgg gaatgaaaac atagctgtcg acatcatgga aaaggctgtc
    44461 atggagatga ggtaatcacg cataaaatta gctggtccac ctggtgtctc ctggtagatg
    44521 ccagaaaaga ataaatagaa agccgtcggc attcctacgg ataataaata atagacgagt
    44581 tgccgtttgg tcaataaaaa ttctatctta tttaatgcta tccatcgttt catcttagtc
    44641 atctcctttt tgcgtttctt caaagattgt atccagcaaa ctacgattat taacttcgat
    44701 ttcttgcatc ctacatcctg cttgggctaa tagttcccag aaagcatctg cttctcgagt
    44761 gactacttgt aaagaatctt gctttagggt ccagttttca accaaatttg actgctctac
    44821 gacttccttg taagctatag gaaggataaa gtgcttttct atttcctcgc tacgcatagc
    44881 tagaggcgtc gtatctcgaa tcaactctcc cttatttaag agcaaaatgc ggtctgcagt
    44941 gtgttccact tcctcaatat aatgggacga atagagaatg gtgactcctt gcgcttttaa
    45001 ctcctggaca atttcccaaa aacgttgacg agttgaggta tccatggacg cagtaggctc
    45061 atctaaaaaa acaatctttg gtcgcccaat taaggtcaag acgaaagaaa agagacgctt
    45121 ttgaccgcct gataattttt ctgccaactg ttctttttgt tgcttgacaa actgcaatag
    45181 ttgatcaatt tcctgattgc tcaaaggatt tggatagata cgttgaaaga aagcaatcaa
    45241 ctctttaact tttaatttct gaacgattac attttcttga gggaggtaag ccctagtata
    45301 gtctaactta gaactcgtca ctggtaaacc ttgaatagat acttgaccgc ttgtgaccag
    45361 tttatctcca agcaaacaat ctaagagtgt tgtctttccg gcaccatttg gaccaattaa
    45421 ggcaacacat tcaccatcgt tgatttcaaa ggagatattc cgcaaaattt ccttgtcttt
    45481 tattttctta ctcaatttct caactttaac caccgtcatg agactctcct ttcaaccact
    45541 ccattcccat aaggaaaacg acgaaaatca taaatccaaa ccccaaagca ccacgaatga
    45601 attggcgaag caaggcttga tcaaaccaat cagtaaacat ttccactaac cataccaaga
    45661 gtgacaggcc gataaagaaa tagatgatcc ctctcttcat tcctcaaact cctttttcac
    45721 atctctgact aatttcaaac cttctctaac aagccaagac atgattccaa agccagcaaa
    45781 gaccttccaa ggaaaatggt agaaatcctc atccaatccc gaaaacatga gataggtcat
    45841 aactcctgct actactaaac ttactgcgat aatcatttta tttctcatct cttcttcccc
    45901 catttcatac tacaattata gtcttttaaa atcagaggag acagaagctt ctgtcactag
    45961 aaaatatgac aaatgtcata aaaaattctg ttcaaaacaa gcaagataca ctatacaata
    46021 aaacacaatc agaaaaatct aaggcaactt cctcaaaaga gatatcaaac ccaattcaca
    46081 ccataatgta aactaatact tatttaaaat caaaaagagt aaaaattttt atcagacaaa
    46141 cacatatata gtgtattgaa tctataacag taggccttaa atactaaaat atttctataa
    46201 attaatttaa ctttcctgat agaactgttc atatcttatt tcaattctct atattatacg
    46261 ttgaaccaaa cccttctatt gctttcttaa aaatttataa gagttataaa atctgttaaa
    46321 tttcaatgtg tatatctaaa ctacggtatt tattgaaaag actggagaca aaaagtatac
    46381 gctgccaaaa tgaattactg aaaatcaaaa aagagagaac caaactgatt ccctcttaat
    46441 gtatataata tctagtttta aaaatacaca ctcacatatc tctgt
//
LOCUS       DBEJAU010000009        44507 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC323 isolate 683620
            SAMN38261939-rid24807223.denovo.009, whole genome shotgun sequence.
ACCESSION   DBEJAU010000009 DBEJAU010000000
VERSION     DBEJAU010000009.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261939
            Sequence Read Archive: SRR26833919
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 44507)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 44507)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576303.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576303.1
            Genome Coverage       :: 154x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/19/2025 01:05:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,121
            CDSs (total)                      :: 2,078
            Genes (coding)                    :: 1,943
            CDSs (with protein)               :: 1,943
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 36
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 72 of 135
            Pseudo Genes (incomplete)         :: 63 of 135
            Pseudo Genes (internal stop)      :: 51 of 135
            Pseudo Genes (multiple problems)  :: 46 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..44507
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261939-rid24807223.denovo.009"
                     /strain="GPSC323"
                     /isolate="683620"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            <1..2660
                     /locus_tag="ACL29Z_000570"
     CDS             <1..2660
                     /locus_tag="ACL29Z_000570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000682791.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009986 - cell surface [Evidence IEA]"
                     /codon_start=3
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HGR0068923.1"
                     /translation="KGDKGERGEDGKTPEVTVTPGKDGHSTDITFTVPGKDPVTVNVK
                     DGENGLNGKTPKVDLLRVQGKNGNPSHTVVTFYTDENNDGKYTPGTDELLGSEMIKDG
                     AKGADGRDGKSLLTVKDGKETKVYQEDPANPGQPLNPEKPLAVIRDGVDGKSPTVTAV
                     RKDEAGHKGVEITVDNHDGSQPTTVFVQDGAKGKTGATGQDGQTPTITTQRGQDGQST
                     VVTITTSGKDPVTFTVKDGKNGKDGRAPKIKVEDITSPSRIRRDTDAAATPTRNGIRV
                     TVYDDVNDNGVYDEGVDKVLNSKDIYNGIDGRDGSAPTITTKDNGDGTHTITVQNPDG
                     SESTTVVKDGKDGKTANITTTENPDGSHTITVTNPDGSTKETVVKNGKDGKTPKVEVT
                     DNNDGTHTVKVTDGDGNVTNAIIKDGKDGKAATATTTENPDGSHTVTITNPDGTKNEF
                     VVKNGRDGVDGRTPTASVRDNGDGSHTIVITNPEGVTTETTVRDGKSPKVTITDEQNG
                     THKISVLNGDGTTTETIIKDGKSPVATVRDNQDGTYTIRVENGNGTVSETTVRDGKSP
                     TAKVVDNGDGTHTITVVNSDGTTTTTTVRDGREPKLEVIDNNDGSHTIKVTGADGKET
                     TTTIFDGKSPKANIVDNGDGTHTLTIVDSDGREYKSIIKDGKDGKDGVSPTVTVENNN
                     DGTHVVTITNPDGSKTEMVIKDGKDGKSPKVSVEDNGDGSHTITIINSDGTVTKTVIK
                     DGKDGRDGRDGRDGKDGKDGKCGCQDKPVTPSNDKPVPPTPNVPTPEVPVKPVPAQPT
                     PNVPTPEVPVQPTPAVPTPNVPVPKQPVVPTPAQPATPVNANPVAPTTGKENRGDKLP
                     ETGSQSDYISVLLGSGILLSLYVGRRKED"
     gene            complement(2897..3445)
                     /locus_tag="ACL29Z_000571"
     CDS             complement(2897..3445)
                     /locus_tag="ACL29Z_000571"
                     /EC_number="1.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000039625.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008752 - FMN reductase (NAD(P)H) activity
                     [Evidence IEA];
                     GO_function: GO:0010181 - FMN binding [Evidence IEA];
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA];
                     GO_function: GO:0052873 - FMN reductase (NADPH) activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NADPH-dependent FMN reductase"
                     /protein_id="HGR0068924.1"
                     /translation="MSKKVLFIVGSLRQGSFNHQMALEAEKALAGKAEVSYLDYSALP
                     LFSQDLEVPTHPAVAAAREAVLVADAIWIFSPVYNFSIPGTVKNLLDWLSRALDLSDT
                     RGASALQDKFVTVSSVANAGHDQLFAIYKDLLPFIRTQGVGDFTAARVNDSAWADGKL
                     VLEETVLNSLEKQAQDLVEAIQ"
     gene            3766..4254
                     /locus_tag="ACL29Z_000572"
     CDS             3766..4254
                     /locus_tag="ACL29Z_000572"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000747178.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5590 domain-containing protein"
                     /protein_id="HGR0068925.1"
                     /translation="MKKRQNKAKNNLLWQYGLGMTILFVVISGSFLYMVSLSMKPYQT
                     AKSEGEKLAQQYAGLEQAVQVDLYNGLESYYSVLGRNKQQEALAVLIGKDDHKIYVYQ
                     LNQGVSQEKAETVSKEKGAGEIDKITFGRYQDKPIWEVKSGSDFYLVDFETGALVNKE
                     GL"
     gene            4251..5438
                     /locus_tag="ACL29Z_000573"
     CDS             4251..5438
                     /locus_tag="ACL29Z_000573"
                     /EC_number="2.6.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000777780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008483 - transaminase activity [Evidence
                     IEA];
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA];
                     GO_process: GO:0009058 - biosynthetic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HGR0068926.1"
                     /translation="MKLSNRVLEMEESVTLAAGARAKALKAEGRDILSLTLGEPDFTT
                     PKNIQDAAIASIRDGRASFYTVTSGLPELKAAVNSYFERFYGYSVASNQVTVAAGAKY
                     SLYTFFMAVVNPGDEVIIPTPYWVSYGDQVKMAEGVPVFVSAKEDNHFKVTVEQLEAA
                     RTDKTKVLVLNSPSNPTGMIYTREELLAIGNWAVENDILILADDIYGRLVYNGHEFTP
                     ISSLSEAIRKQTVVINGVSKTYAMTGWRIGYAVGEADIIAAMSKIAGQTTSNPSAVAQ
                     YAAVEALSGEQDTVESMRQAFEERLNTIYPLLAEVPGFEVVKPQGAFYLFPNVKKAME
                     MKGYTDVTDFTTAILEEAEVALVTGAGFGAPENVRLSYATDLDTLKEAVERLKAFMGS
                     END"
     gene            5431..5796
                     /locus_tag="ACL29Z_000574"
     CDS             5431..5796
                     /locus_tag="ACL29Z_000574"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HGR0068927.1"
                     /translation="MIDHFEIKVKDLQISEGFYRSFLAPLDYKMAFKTSSLISFLSPN
                     SPHPGGDFWLTQGTQDPVHFAFLAENKEEVQACYEAGIEAGGRDNGVPGYRSEHPIYY
                     AAFMIDLDGNNIEVVCHKE"
     gene            5812..7158
                     /gene="asnS"
                     /locus_tag="ACL29Z_000575"
     CDS             5812..7158
                     /gene="asnS"
                     /locus_tag="ACL29Z_000575"
                     /EC_number="6.1.1.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000038477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004816 - asparagine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006421 - asparaginyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="asparagine--tRNA ligase"
                     /protein_id="HGR0068928.1"
                     /translation="MMTKRVTIIDVKDYVGQEVTIGAWVANKSGKGKIAFLQLRDGTA
                     FFQGVAFKPNFVEKFGEEVGLEKFDVIKRLSQETSVYVTGIVKEDERSKFGYELDITD
                     IEVIGESQDYPITPKEHGTDFLMDNRHLWLRSRKQVAVLQIRNAIIYATYEFFDKNGF
                     MKFDSPILSGNAAEDSTELFETDYFGTPAYLSQSGQLYLEAGAMALGRVFDFGPVFRA
                     EKSKTRRHLTEFWMMDAEYSYLTHDESLDLQEAYVKALLQGVLDRAPQALETLERDTE
                     LLKRYIAEPFKRITYDQAIDLLQEHENDEDADYEHLEHGDDFGSPHETWISNHFGVPT
                     FVMNYPAAIKAFYMKPVPGNPERVLCADLLAPEGYGEIIGGSMREEDYDALVAKMDEL
                     GMDRTEYEFYLDLRKYGTVPHGGFGIGIERMVTFAAGTKHIREAIPFPRMLHRIKP"
     gene            7311..7601
                     /gene="rpsF"
                     /locus_tag="ACL29Z_000576"
     CDS             7311..7601
                     /gene="rpsF"
                     /locus_tag="ACL29Z_000576"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018030687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0000314 - organellar small ribosomal
                     subunit [Evidence IEA];
                     GO_component: GO:0022627 - cytosolic small ribosomal
                     subunit [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S6"
                     /protein_id="HGR0068929.1"
                     /translation="MAKYEILYIIRPNIEEEAKNALVARFDSILTDNGATVVESKTWE
                     KRRLAYEIQDFREGLYHIVNVEANDDAALKEFDRLSKINADILRHMIVKIDA"
     gene            7613..8083
                     /gene="ssbA"
                     /locus_tag="ACL29Z_000577"
     CDS             7613..8083
                     /gene="ssbA"
                     /locus_tag="ACL29Z_000577"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003083754.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein SsbA"
                     /protein_id="HGR0068930.1"
                     /translation="MINNVVLVGRMTRDAELRYTPSNVAVATFTLAVNRTFKSQNGER
                     EADFINVVMWRQQAENLANWAKKGSLIGVTGRIQTRSYDNQQGQRVYVTEVVAENFQM
                     LESRSVREGHTGGAYSAPTANYSAPTNSVPDFSRNENPFGATNPLDISDDDLPF"
     gene            8115..8354
                     /gene="rpsR"
                     /locus_tag="ACL29Z_000578"
     CDS             8115..8354
                     /gene="rpsR"
                     /locus_tag="ACL29Z_000578"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983142.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0000314 - organellar small ribosomal
                     subunit [Evidence IEA];
                     GO_component: GO:0022627 - cytosolic small ribosomal
                     subunit [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S18"
                     /protein_id="HGR0068931.1"
                     /translation="MAQQRRGGFKRRKKVDYIAANKIEYVDYKDTELLSRFVSERGKI
                     LPRRVTGTSAKNQRKVTTAIKRARVMALMPFVNED"
     gene            8649..10049
                     /locus_tag="ACL29Z_000579"
     CDS             8649..10049
                     /locus_tag="ACL29Z_000579"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006145273.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional Cof-type HAD-IIB family
                     hydrolase/peptidylprolyl isomerase"
                     /protein_id="HGR0068932.1"
                     /translation="MDAKLRYKAKKIKIVFFDIDDTLRNSKTGFIPTTIPTVFKQLRE
                     KGILTGIASGRGIFGVVPEIRDLKPDFFVTLNGAYIEDKKGQVIYQHQIEKSDVEEYI
                     SWAKQEGIEYGLVGSHDAKLSTRTDMMSEAINPIYPDLDVDPDFHEKEDIYQMWTFED
                     KGDDLHLPDSLSDKLRMVRWHQHSSDIVPISGSKATGVEKVVEHLGLKPEKVMVFGDG
                     LNDLELFDYAGISVAMGISHDKIKEKADYITKTLEEDGIFAALEVFGMVEKELHFPQV
                     DIETVEGPLATIKTNHGDLRIKLFPEHAPKTVANFVSLSKDGYYDGVIFHRIIKDFMI
                     QGGDPTGTGMGGQSIYGESFEDEFSEELYNIRGALSMANAGPNTNGSQFFIVQNQHLP
                     YSKKEITRGGWPEPIAEIYANQGGTPHLDRRHTVFGQLADEASYAVLDAIAAVETGAM
                     DKPVEDVVIETIEIED"
     gene            10051..10410
                     /locus_tag="ACL29Z_000580"
     CDS             10051..10410
                     /locus_tag="ACL29Z_000580"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000689596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S1 RNA-binding domain-containing protein"
                     /protein_id="HGR0068933.1"
                     /translation="MKIGDKLKGRITGIQPYGAFVELETGDTGLIHISEIRTGFIENI
                     HETLKVDEEVQVQVVDLDEFTGKASLSIRTLEEEKYQFPRRRRFSSDRFNYGFAPFRR
                     MLPIWTGEALHHLKKKK"
     gene            10464..11213
                     /locus_tag="ACL29Z_000581"
     CDS             10464..11213
                     /locus_tag="ACL29Z_000581"
                     /EC_number="2.1.1.223"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000390787.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008170 - N-methyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0016430 - tRNA
                     (adenine-N6)-methyltransferase activity [Evidence IEA];
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA1(Val) (adenine(37)-N6)-methyltransferase"
                     /protein_id="HGR0068934.1"
                     /translation="MEEEQLLKSGERINQLFSTDIKIIQNREVFSYSVDSVLLSRFPR
                     FPKKGLIVDFCAGNGAVGLFASTRTQAQILSVEIQERLADMAERSVRLNGLEEQMQVI
                     CDDLKNMPAHIQGSKVDMILCNPPYFKVDPYSNLNESEHYLLARHEITTNLEEICRSA
                     QSILKSNGRLAMVHRPDRLLDILDTLKRHNLAPKRLQFVYPKREKEANMLLIEAIKDG
                     STSGFKVLPPLIVHNDDGSYTPEIEEIYYGS"
     gene            11203..11502
                     /locus_tag="ACL29Z_000582"
     CDS             11203..11502
                     /locus_tag="ACL29Z_000582"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004518 - nuclease activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GIY-YIG nuclease family protein"
                     /protein_id="HGR0068935.1"
                     /translation="MDHKAYMYVLECRDGSYYIGYTTDVRRRLAIHNSGKGAKYTRAR
                     LPVKLIYAQGFASKEEAMSAEALLKRKKRPQKEEFLSENQDRNLLSYFEESWGVL"
     gene            11573..12508
                     /locus_tag="ACL29Z_000583"
     CDS             11573..12508
                     /locus_tag="ACL29Z_000583"
                     /EC_number="3.6.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000036024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004427 - inorganic diphosphate
                     phosphatase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="manganese-dependent inorganic pyrophosphatase"
                     /protein_id="HGR0068936.1"
                     /translation="MSKILVFGHQNPDSDAIGSSVAFAYLAKEAYGLDTEAVALGTPN
                     EETAFVLNYFGVEAPRVITSAKAEGAEQVILTDHNEFQQSVSDIAEVEVYGVVDHHRV
                     ANFETASPLYMRLEPVGSASSIVYRMFKEHGVAVPKEIAGLMLSGLISDTLLLKSPTT
                     HPTDKIIAPELAELAGVNLEEYGLAMLKAGTNLASKSAEELIDIDAKTFELNGNNVRV
                     AQVNTVDIAEVLERQAEIEAAMQAANESNGYSDFVLMITDIVNSNSEILALGANMDKV
                     EAAFNFKLENNHAFLAGAVSRKKQVVPQLTESFNA"
     gene            12595..13107
                     /locus_tag="ACL29Z_000584"
     CDS             12595..13107
                     /locus_tag="ACL29Z_000584"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000892254.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YiiX/YebB-like N1pC/P60 family cysteine
                     hydrolase"
                     /protein_id="HGR0068937.1"
                     /translation="MLENGDLIFVRDGSDMGQAIQTSTGNYSHVAIYLDGMIYHASGQ
                     AGVVCQEPADFFESNHLYDLYVYPEMDIQSVKERACRHLGAPYNASFYPDAAGFYCSQ
                     YIAEILPIFETIPMKFGDGEQEISDFWREYYIELGLPVPLNQAGTNPSQLAASPLLQC
                     KERNLHDSDF"
     gene            13091..13740
                     /locus_tag="ACL29Z_000585"
                     /pseudo
     CDS             13091..13740
                     /locus_tag="ACL29Z_000585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000614493.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1803 domain-containing protein"
     gene            13841..14035
                     /locus_tag="ACL29Z_000586"
     CDS             13841..14035
                     /locus_tag="ACL29Z_000586"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000051203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CsbD family protein"
                     /protein_id="HGR0068938.1"
                     /translation="MSLENKLEQATGAVKEGFGKVTGDSKTELEGAVEKTVAKAKDVV
                     EDAKGAVEGAVEGLKNVFTK"
     gene            complement(14081..15526)
                     /locus_tag="ACL29Z_000587"
     CDS             complement(14081..15526)
                     /locus_tag="ACL29Z_000587"
                     /EC_number="6.3.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--L-
                     lysine ligase"
                     /protein_id="HGR0068939.1"
                     /translation="MIKIETVLDILKKDGLFREIIDQGHYHYNYSKVIFDSISYDSRK
                     VTEDTLFFAKGAAFKKEYLLSAITQGLAWYVAEKDYEVDIPVIIVNDIKKAMSLIAME
                     FYGNPQEKLKLLAFTGTKGKTTATYFAYNILSQGHRPAMLSTMNTTLDGETFFKSALT
                     TPESIDLFDMMNQAVQNDRTHLIMEVSSQAYLVHRVYGLTFDVGVFLNITPDHIGPIE
                     HPSFEDYFYHKRLLMENSRAVIINSDMDHFSVLKEQVEDQDHDFYGSQFDNQIENSKA
                     FSFSATGKLAGDYDIQLIGNFNQENAVAAGLACIRLGASLEDIKKGIAATRVPGRMEV
                     LTQKNGAKVFIDYAHNGDSLKKLINVVETHQTGKIALVLGSTGNKGESRRKDFGLLLN
                     QHPEIQVFLTADDPNYEDPMAIADEISSYINHPVEKIADRQEAIKAAMAITNHELDAV
                     IIAGKGADCYQIIQGKKESYPGDTAVAENYL"
     gene            15632..17254
                     /locus_tag="ACL29Z_000588"
     CDS             15632..17254
                     /locus_tag="ACL29Z_000588"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398581.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="oligosaccharide flippase family protein"
                     /protein_id="HGR0068940.1"
                     /translation="MSHENNHQQAQMLRGTAWLTASNFISRLLGAVYIIPWYIWMGAY
                     AAKANGLFTMGYNIYAWFLLVSTAGIPVAVAKQVAKYNTMREEEHSFALIRSFLGFMT
                     GLGLVFALVLYVFAPWLADLSGVGKDLIPIMQSLAWGVLIFPSMSVIRGFFQGMNNLK
                     PYAMSQIAEQVIRVIWMLLATFIIMKLGSGDYLAAVTQSTFAAFVGMVASFAVLIYFL
                     AQEGSLKRVFETGDKINSKRLLVDTIKEAIPFILTGSAIQLFQILDQLTFINSMSWFT
                     NYSNEDLVVMFSYFSANPNKITMILISVGVSIGSVGLPLLTENYVKGDLKAASRLVQD
                     SLTLLFMFLLPATVGVVMVGEPLYTVFYGKPDSLALGLFVFAVLQSIILGLYMVLSPM
                     LQAMFRNRKAVLYFIYGSIAKLVLQLPTIALFHSYGPLISTTIALIIPNVLMYRDICK
                     VTGVKRKVILKRTILISLLTLVMFLLIGTTQWLLGFFFQPSGRLWSFFYVALVGAMGG
                     GLYMVMSLRTYLLDKVIGKAQADRLRAKFKLS"
     gene            17457..19415
                     /locus_tag="ACL29Z_000589"
     CDS             17457..19415
                     /locus_tag="ACL29Z_000589"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000748873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptide ABC transporter substrate-binding
                     protein"
                     /protein_id="HGR0068941.1"
                     /translation="MKKSKSKYLTLAGLVLGTGVLLSACGNSSTASKTYNYVYSSDPS
                     SLNYLAENRAATSDIVANLVDGLLENDQYGNIIPSLAEDWTVSQDGLTYTYKLRKDAK
                     WFTSEGEEYAPVTAQDFVTGLQYAADKKSEALYLVQDSVAGLDDYITGKTSDFSTVGV
                     KALDDQTVQYTLVKPELYWNSKTLATILFPVNADFLKSKGDDFGKADPSSILYNGPFL
                     MKALVSKSAIEYKKNPNYWDAKNVFVDDVKLTYYDGSDQESLERNFTAGAYTTARLFP
                     NSSSYEGIKEKYKNNIIYSMQNSTSYFFNFNLDRKSYNYTSKTSDIEKKSTQEAVLNK
                     NFRQAINFAFDRTSYGAQSEGKEGATKILRNLVVPPNFVSIKGKDFGEVVASKMVNYG
                     KEWQGINFADGQDPYYNPEKAKAKFAEAKKELEAKGVQFPIHLDKTVEVTDKVGIQGV
                     SSIKQSIESVLGSDNVVIDIQQLTSDEFDSSGYFAQTAAQKDYDLYHGGWGPDYQDPS
                     TYLDIFNTNSGGVLQNLGLEPGEANDKAKEVGLDVYTQMLEEANKEQDPAKRYEKYAD
                     IQAWLIDSSLVLPSVSRGGTPSLRRTVPFAAAYGLTGTKGVESYKYLKVQDKIVTTDE
                     YAKAREKWLKEKEESNKKAQEELAKHVK"
     gene            19587..20522
                     /locus_tag="ACL29Z_000590"
     CDS             19587..20522
                     /locus_tag="ACL29Z_000590"
                     /inference="COORDINATES: protein motif:HMM:NF012869.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGR0068942.1"
                     /translation="MKLKLLRVDTKVIMGSFLLVLSSLLALLLPLILKGLIDGSSIEN
                     IGSKVFQSFLIFIGQALFSSIGYYLFSQSGEKKIAKIRKKVTEGLIYAEKSFFDKSQS
                     GELTSAIVNDTSVIREFLITTFPNIILSLVMVLGSIVVLFSLDWNLSLLLFITLPCMM
                     FIILPLSNISEKYSRRLQEEIGFLTGQLTEKIQEHELIKTNQAEKSVQDVLDNCIERV
                     QNNSLKSDRITSFETPFALLFIFATIAVMLTYGGYRVSAGYISVGTLVSFLIYLFQLL
                     NPISNIANFVTVYSRSKGSSVALENLLAVPKEKFE"
     gene            20547..21269
                     /locus_tag="ACL29Z_000591"
     CDS             20547..21269
                     /locus_tag="ACL29Z_000591"
                     /EC_number="7.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGR0068943.1"
                     /translation="MNFNHVYFGYDENRPVLKDITCSIFKGQKIAFVGPSGSGKSTIV
                     RLLEQFYKPLSGDILMEQSSIYDFNLKEWRSKIAWVSQNNAVLSGSIRDNLCLGLNRL
                     VTDDELMKVLDLVSLGDEIRSMKEGLDTEVGERGRFLSGGQSQRLQIARTYLKDAEIL
                     IFDESTANLDADSEYAIISILYSALKEKTVVIIAHRLSTVKDVDCIFFLEEGKITGSG
                     THKELLENHERYARFVQEQMIE"
     gene            21427..22521
                     /locus_tag="ACL29Z_000592"
     CDS             21427..22521
                     /locus_tag="ACL29Z_000592"
                     /EC_number="2.5.1.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007521335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cystathionine gamma-synthase"
                     /protein_id="HGR0068944.1"
                     /translation="MSKELHINTILAQAGIKSDEATGALVTPLHFSTTYQHPEFGRST
                     GFDYTRTKNPTRSKAEEVLAAIESADYALATSSGMSAIVLAFSVFPVGSKVLAVRDLY
                     GGSFRWFNQVEQEGHFHFTYANTEEELIAELEKDVDVLYIETPTNPLMLEFDIEKLAK
                     LAHAKGAKVVVDNTFYSPIYQRPIEDGADIVLHSATKYLAGHNDVLAGVVVTNSLELY
                     EKLFYNLNTTGAVLSPFDSYQLLRGLKTLSLRMERSTANAQEVVAFLKDSPAVKEVLY
                     TGRGGMISFKVADETRIPHILNSLKVFSFAESLGGVESLITYPTTQTHADIPAEVRHS
                     YGLTDDLLRLSIGIEDARDLIADLRQALEG"
     gene            22529..23695
                     /locus_tag="ACL29Z_000593"
     CDS             22529..23695
                     /locus_tag="ACL29Z_000593"
                     /EC_number="4.4.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000521357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA];
                     GO_function: GO:0047804 - cysteine-S-conjugate beta-lyase
                     activity [Evidence IEA];
                     GO_process: GO:0009086 - methionine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MalY/PatB family protein"
                     /protein_id="HGR0068945.1"
                     /translation="MGKYDFTSLPNRLGHHTYKWKETETDSEVLPAWIADMDFVVLPE
                     IRQAVQTYADQLVYGYTYASEDLIKEVQKWEATQYGYNFDKEALVFIEGVVPAISTAI
                     QTFTKEGEAVLINTPVYPPFARSVKLNNRRLITNSLVEKDGLFEIDFDQLEKDLVEEE
                     VKLYILCNPHNPGGRVWEKEVLEKIGQLCQKHGVLLVSDEIHQDLTLFGHKHQSFNTI
                     NPAFKNFAIVLSSATKTFNIAGTKNSYAVIENPKLRLAFQKRLLANNQHEISGLGYLA
                     TEAAYRYGKDWLEELKQVFEDHINYVVDLFGKETKIKVMKPQGTYLIWLDFSAYDLTD
                     ETLQELLRNEAKVILNRGLDFGEEGSLHARINIAMPKSLLQEVCQRIVATFAKR"
     gene            23788..26886
                     /locus_tag="ACL29Z_000594"
     CDS             23788..26886
                     /locus_tag="ACL29Z_000594"
                     /EC_number="3.6.4.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001096241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004386 - helicase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HGR0068946.1"
                     /translation="MAKLIPGKIRIEGVALYETGKVDIIKEKNNRLYARVAEEELRYS
                     LEDDLVFCACDFFQKRGYCVHLAALEHFLKNDERGQEILWSLEEGHEEKEAVETKVTL
                     GGKFLDRILSPKSECAYELSAVGQVEAGTNHILWTLRIGQINSQKYYIIRDIPLFLRI
                     VEQRKSYMIGKIYEESLSWETFDDASQELLTFLHGLTEEGLVPDLFFQNQGRHLFFPL
                     TFFEQGVNLLMALPHFQFDHQVDSYQTLLFQDMHADANLFAFAVTEYSDYFEMEISES
                     PRVNVFYQGAVLFHKGQVYFLTDQQMRLLKEIKALPVGQQGKKYLQFDSSDRDKLASC
                     LTLFIQMGTVSAPERLQIKTFAPSFYFDREEDNRIRLEIQFDYGNRQVSSRQELEELP
                     FSSDADLEERIFQVCLAAGFEADFQSWRQALKAESVYHFFHDIIPVFEKLGHVDLSDK
                     LEELYSLASPQVQIASKGGLLEIQFDFQNIAQEEIDQAMQALVANQDFYIDSSNQVYF
                     FDEETKKIRQNLQELGQFELKDGTLQARKSLAYSLAHLFEGRDRVSFSQEFQNLAQDL
                     THPEDFPLQATQVKADLRDYQEKGIGWLQMLHHYGFGGILADDMGLGKTLQTIAFLTS
                     QVTKESRVLILAPSGLIYNWADEFQKFAPQLDVAVVHGLKASREEILAESHQIYVTSY
                     ATFRQDSELYQGMAFDFLFLDEAQVMKNAQTKIAQTLRQFVVPSVFALSGTPIENHLG
                     ELWSIFQIVMPGLLPSKKEFMKLPAERVAQFIKPFVMRRKKEEVLTELPDLIEVVYKN
                     ELEDQQKAIYLAQLQQMRDHLAQVSEQEFQRSRVEILSGLMRLRQICDTPALFMEDYQ
                     GASGKLDSLRDLLVQVADGGHRVLIFSQFKGMLEKIEQELPDLGLTSFKITGSTPAKE
                     RQDMTKAFNQGERDAFLISLKAGGVGLNLTGADTVILVDLWWNPAVEAQAIGRAHRMG
                     QEETVEVYRLVTKGTIEEKIQELQEQKKHLVSQVLDGTESRGSLTLAEIREILGISEA
                     ST"
     gene            26934..27551
                     /locus_tag="ACL29Z_000595"
     CDS             26934..27551
                     /locus_tag="ACL29Z_000595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000808222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cystathionine gamma-synthase"
                     /protein_id="HGR0068947.1"
                     /translation="MKQERFPLVSDDEVMLTEMPVMNLYDESDLISNIKGEYRDKNYL
                     EWAPIAEEKPVKPIEKQVEKPKKAPLGVKKEGKSYAEVAREEARADLKKKRSANYLTQ
                     DFSLARRHSQPSLVRQGNQPTAPFQKENPGEFVKYSQKLTQSHYILAEEVHSIPTKNE
                     EVSAPAPKKNNYDFLKKSQIYNKKSKQTEQERRVAQELNLTRMTE"
     gene            27562..28896
                     /gene="murC"
                     /locus_tag="ACL29Z_000596"
     CDS             27562..28896
                     /gene="murC"
                     /locus_tag="ACL29Z_000596"
                     /EC_number="6.3.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015511317.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008763 - UDP-N-acetylmuramate-L-alanine
                     ligase activity [Evidence IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramate--L-alanine ligase"
                     /protein_id="HGR0068948.1"
                     /translation="MSKTYHFIGIKGSGMSALALMLHQMGHKVQGSDVEKYYFTQRGL
                     EQAGITILPFDEKNLDGDMEIIAGNAFRPDNNVEIAYADQNGISYKRYHEFLGSFMRD
                     FVSMGVAGAHGKTSTTGMLSHVLSHITDTSFLIGDGTGRGSANAKYFVFESDEYERHF
                     MPYHPEYSIITNIDFDHPDYFTSLEDVFNAFNDYAKQITKGLFVYGEDAELRKITSDA
                     PIYYYGFEAEGNDFVASDLLRSITGSTFTVHFRGQNLGQFHIPTFGRHNIMNATAVIG
                     LLYTAGFDLNLVREHLKTFAGVKRRFTEKIVNDTVIIDDFAHHPTEIIATLDAARQKY
                     PSKEIVAVFQPHTFTRTIALLDDFAHALNQADAVYLAQIYGSAREVDHGDVKVEDLAN
                     KINKKHQVITVENVSPLLDHDNAVYVFMGAGDIQTYEYSFERLLSNLTSNVQ"
     gene            28906..29370
                     /locus_tag="ACL29Z_000597"
     CDS             28906..29370
                     /locus_tag="ACL29Z_000597"
                     /EC_number="2.3.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000405282.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0016746 - acyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HGR0068949.1"
                     /translation="MEIPIKIIQASKSDLPEIGALQTSSFPAEKQQLSHILEESIRKC
                     ADTFLLARDENQLLGYILSSPQSDNPQCLKVHSLVIESDHQRQGLGTLLLAALKEVAV
                     ELDYKGIRLESPDELLSYFEMNGFVDEEATLLYATSQGYSMIWFNPFYLEEQ"
     gene            29367..29861
                     /locus_tag="ACL29Z_000598"
     CDS             29367..29861
                     /locus_tag="ACL29Z_000598"
                     /EC_number="2.3.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000702438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0016746 - acyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HGR0068950.1"
                     /translation="MKIRQARLEDLDRIVELEFENFSVEEAIPPSVFEAHLREIQTSF
                     LVAEKEGRIMGYIEGPVGLHRHLQDQSFTEEIKDYSHEPGGYISVTCLSIAKEAQGLG
                     LGQKLLTALKEVALEDERDGINLTCHDYLIAYYEKHGFVNEGQSQSTFAGETWYDMVW
                     EMKK"
     gene            29942..31597
                     /gene="mltG"
                     /locus_tag="ACL29Z_000599"
     CDS             29942..31597
                     /gene="mltG"
                     /locus_tag="ACL29Z_000599"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001291636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008932 - lytic endotransglycosylase
                     activity [Evidence IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA];
                     GO_process: GO:0071555 - cell wall organization [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="endolytic transglycosylase MltG"
                     /protein_id="HGR0068951.1"
                     /translation="MSEKSREEEKLSFKEQILRDLEKVKGYDEVLKEDEAVVRTPANE
                     PSTEELMADSLSTVEEIMRKAPTVPTHPSQGVPASPADEIQRETPGVPSHPSQDVPSS
                     PAEESGSRPGPGPVRPKKLEREYNETPTRVAVSYTTAEKKAEQAGPETPTPATETVDI
                     IRDTSRRSRREGAKPVKPKKEKKSHVKAFVISFLVFLALLSAGGYFGYQYVLDSLLPI
                     DANSKKYVTVGIPEGSNVQEIGTTLEKAGLVKHGLIFSFYAKYKNYTDLKAGYYNLQK
                     SMSTEDLLKELQKGGTDEPQEPVLATLTIPEGYTLDQIAQAVGQLQGDFKESLTAEAF
                     LAKVQDETFISQAVAKYPTLLESLPVKDSGARYRLEGYLFPATYSIKESTTIESLIDE
                     MLAAMDKNLSPYYSTIKSKNLTVNELLTIASLVEKEGAKTEDRKLIAGVFYNRLNRDM
                     PLQSNIAILYAQGKLGQNISLAEDVAIDTNIDSPYNVYKNVGLMPGPVDSPSLDAIES
                     SINQTKSDNLYFVADVTEGKVYYANNQEDHDRNVAEHVNSKLN"
     gene            31668..32150
                     /gene="greA"
                     /locus_tag="ACL29Z_000600"
     CDS             31668..32150
                     /gene="greA"
                     /locus_tag="ACL29Z_000600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018370745.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription elongation factor GreA"
                     /protein_id="HGR0068952.1"
                     /translation="MAEKTYPMTLEEKEKLEKELEELKLVRRPEVVERIKIARSYGDL
                     SENSEYEAAKDEQAFVEGQISSLETKIRYAEIVNSDAVAQDEVAIGKTVTIQEIGEDE
                     EEVYIIVGSAGADAFVGKVSNESPIGQALIGKKTGDTATIETPVGSYDVKILKVEKTA
                     "
     gene            32658..33056
                     /locus_tag="ACL29Z_000601"
     CDS             32658..33056
                     /locus_tag="ACL29Z_000601"
                     /EC_number="2.3.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000428147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0016746 - acyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HGR0068953.1"
                     /translation="MENKESHKSQEIGNLIRVYNRSKREEAESEPLNLYVEDEKGNLL
                     AGLIAETFGNWLEIEYLFVKEELRGQGIGSKLLQQAESEAKNRNCCFAFVNTYQFQAP
                     DFYQKHGYKEVFSLQDCLYIRQRYYYQKNL"
     gene            33501..34507
                     /locus_tag="ACL29Z_000602"
                     /pseudo
     CDS             33501..34507
                     /locus_tag="ACL29Z_000602"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001153868.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
     gene            34582..34782
                     /locus_tag="ACL29Z_000603"
     CDS             34582..34782
                     /locus_tag="ACL29Z_000603"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015545704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit C"
                     /protein_id="HGR0068954.1"
                     /translation="MNLTFLGLCIACMGVSVGEGLLMNGLFKSVARQPDMLSEFRSLM
                     FLGVAFIEGTFFVTLVFSFIIK"
     gene            34817..35533
                     /gene="atpB"
                     /locus_tag="ACL29Z_000604"
     CDS             34817..35533
                     /gene="atpB"
                     /locus_tag="ACL29Z_000604"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000392848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015078 - proton transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0015986 - proton motive force-driven ATP
                     synthesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit A"
                     /protein_id="HGR0068955.1"
                     /translation="MEESINPIISIGPVIFNLTMLAMTLLIVGVIFVFIYWASRNMTL
                     KPKGKQNVLEYVYDFVIGFTEPNIGSRYMKDYSLFFLCLFLFMVIANNLGLMTKLQTI
                     DGTNWWSSPTANLQYDLTLSFLVILLTHIESVRRRGFKKSIKSFMSPVFVIPMNILEE
                     FTNFLSLALRIFGNIFAGEVMTSLLLLLSHQAIYWYPVAFGANLAWTAFSVFISCIQA
                     YVFTLLTSVYLGNKINIEEE"
     gene            35547..36041
                     /gene="atpF"
                     /locus_tag="ACL29Z_000605"
     CDS             35547..36041
                     /gene="atpF"
                     /locus_tag="ACL29Z_000605"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006145707.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0045263 - proton-transporting ATP
                     synthase complex, coupling factor F(o) [Evidence IEA];
                     GO_function: GO:0015078 - proton transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0015986 - proton motive force-driven ATP
                     synthesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit B"
                     /protein_id="HGR0068956.1"
                     /translation="MHVTVGELIGNFILITGSFILLLVLIKKFAWSNITGIFEERAEK
                     IASDIDRAEEARQKAEVLAQKREDELAGSRKEAKTIIENAKETAEQSKANILADAKLE
                     AGHLKEKANQEIAQNKVEALQSVKGEVADLTISLAGKIISQNLDSHAHKALIDQYIDQ
                     LGEA"
     gene            36041..36577
                     /locus_tag="ACL29Z_000606"
     CDS             36041..36577
                     /locus_tag="ACL29Z_000606"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000358986.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit delta"
                     /protein_id="HGR0068957.1"
                     /translation="MDKKTVKVIEKYSMPFVQLVLEKGEEDRIFSDLTQIKQVVEKTG
                     LPSFLKQVAVDESDKEKTIAFFQDSVSPLLQNFIQVLAYNHRANLFYDVLVDCLNRLE
                     KETNRFEVTITSAHPLTDEQKTRLLPLIEKKMSLKVRSVKEQIDESLIGGFVIFANHK
                     TIDVSIKQQLKVVKENLK"
     gene            36592..38097
                     /gene="atpA"
                     /locus_tag="ACL29Z_000607"
     CDS             36592..38097
                     /gene="atpA"
                     /locus_tag="ACL29Z_000607"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011889023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0045261 - proton-transporting ATP
                     synthase complex, catalytic core F(1) [Evidence IEA];
                     GO_component: GO:0045262 - plasma membrane
                     proton-transporting ATP synthase complex, catalytic core
                     F(1) [Evidence IEA];
                     GO_function: GO:0046933 - proton-transporting ATP synthase
                     activity, rotational mechanism [Evidence IEA];
                     GO_process: GO:0015986 - proton motive force-driven ATP
                     synthesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit alpha"
                     /protein_id="HGR0068958.1"
                     /translation="MAINAQEISALIKQQIENFKPNFDVTETGVVTYIGDGIARAHGL
                     ENVMSGELLNFENGSYGMAQNLESTDVGIIILGDFTDIREGDTIRRTGKIMEVPVGES
                     LIGRVVDPLGRPVDGLGEIHTDKTRPVEAPAPGVMQRKSVSEPLQTGLKAIDALVPIG
                     RGQRELIIGDRQTGKTTIAIDTILNQKDQDMICIYVAIGQKESTVRTQVETLRQYGAL
                     DYTIVVTASASQPSPLLFLAPYAGVAMAEEFMYQGKHVLIVYDDLSKQAVAYRELSLL
                     LRRPPGREAFPGDVFYLHSRLLERSAKVSDELGGGSITALPFIETQAGDISAYIATNV
                     ISITDGQIFLGDGLFNAGIRPAIDAGSSVSRVGGSAQIKAMKKVAGTLRIDLASYREL
                     EAFTKFGSDLDAATQAKLNRGRRTVEVLKQPVHKPLPVEKQVTILYALTHGFLDTVPV
                     DDIVRFEEEFHAFFDAQHPEILETIRDTKDLPEEAVLDAAITEFLNQSSFQ"
     gene            38113..38991
                     /locus_tag="ACL29Z_000608"
     CDS             38113..38991
                     /locus_tag="ACL29Z_000608"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002895995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0045261 - proton-transporting ATP
                     synthase complex, catalytic core F(1) [Evidence IEA];
                     GO_function: GO:0046933 - proton-transporting ATP synthase
                     activity, rotational mechanism [Evidence IEA];
                     GO_process: GO:0015986 - proton motive force-driven ATP
                     synthesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit gamma"
                     /protein_id="HGR0068959.1"
                     /translation="MAVSLNDIKTKIASTKNTSQITNAMQMVSAAKLGRSEEAARNFQ
                     VYAQKVRKLLTDILHGNGAGASTNPMLISRSVKKTGYIVITSDRGLVGGYNSSILKAV
                     MELKEEYHPDGKGFEMICIGGMGADFFKARGIQPLYELRGLSDQPSFDQVRKIISKTV
                     EMYQNELFDELYVCYNHHVNTLTSQMRVEQMLPIVDLDPNEADEEYSLTFELETSREE
                     ILEQLLPQFAESMIYGAIIDAKTAENAAGMTAMQTATDNAKKVINDLTIQYNRARQAA
                     ITQEITEIVAGASALE"
     gene            39077..40483
                     /gene="atpD"
                     /locus_tag="ACL29Z_000609"
     CDS             39077..40483
                     /gene="atpD"
                     /locus_tag="ACL29Z_000609"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0045261 - proton-transporting ATP
                     synthase complex, catalytic core F(1) [Evidence IEA];
                     GO_component: GO:0045262 - plasma membrane
                     proton-transporting ATP synthase complex, catalytic core
                     F(1) [Evidence IEA];
                     GO_function: GO:0046933 - proton-transporting ATP synthase
                     activity, rotational mechanism [Evidence IEA];
                     GO_process: GO:0015986 - proton motive force-driven ATP
                     synthesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit beta"
                     /protein_id="HGR0068960.1"
                     /translation="MSSGKIAQVIGPVVDVLFAAGEKLPEINNALVVYKNDERKTKIV
                     LEVALELGDGMVRTIAMESTDGLTRGMEVLDTGRPISVPVGKETLGRVFNVLGDTIDL
                     EAPFTEDAERQPIHKKAPTFDELSTSSEILETGIKVIDLLAPYLKGGKVGLFGGAGVG
                     KTVLIQELIHNIAQEHGGISVFAGVGERTREGNDLYWEMKESGVIEKTAMVFGQMNEP
                     PGARMRVALTGLTIAEYFRDVEGQDVLLFIDNIFRFTQAGSEVSALLGRMPSAVGYQP
                     TLATEMGQLQERITSTKKGSVTSIQAIYVPADDYTDPAPATAFAHLDSTTNLERKLVQ
                     LGIYPAVDPLASSSRALAPEIVGEEHYAVAAEVKRVLQRYHELQDIIAILGMDELSDE
                     EKTLVARARRIQFFLSQNFNVAEQFTGQPGSYVPVAETVRGFKEILDGKYDHLPEDAF
                     RGVGSIEDVIAKAEKMGF"
     gene            40494..40913
                     /locus_tag="ACL29Z_000610"
     CDS             40494..40913
                     /locus_tag="ACL29Z_000610"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0045261 - proton-transporting ATP
                     synthase complex, catalytic core F(1) [Evidence IEA];
                     GO_function: GO:0046933 - proton-transporting ATP synthase
                     activity, rotational mechanism [Evidence IEA];
                     GO_process: GO:0015986 - proton motive force-driven ATP
                     synthesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit epsilon"
                     /protein_id="HGR0068961.1"
                     /translation="MAQLTVQIVTPDGLVYDHHASYVSVRTLDGEMGILPRHENMIAV
                     LAVDEVKVKRIDDKDHVNWIAVNGGVIEIANDMITIVADSAERARDIDISRAERAKLR
                     AERAIEEAQDKHLIDQERRAKIALQRAINRINVGNRL"
     gene            complement(40958..41971)
                     /locus_tag="ACL29Z_000611"
     CDS             complement(40958..41971)
                     /locus_tag="ACL29Z_000611"
                     /EC_number="3.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000665618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0052689 - carboxylic ester hydrolase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="lactonase family protein"
                     /protein_id="HGR0068962.1"
                     /translation="MKETVYFGTYTRRTSQGIYKADFDTETGQLSNLELFAAEPSPTY
                     LAFDQHQHLYTVGSQDDKGGIAAYQTDGTVLNHVVEEGAPHCYVAVDEKRDLVYAANY
                     HKGQVLVYKRQEDGSLLLSDMDQHSGQGPHENQASPHVHYTDLTPDHYLVTCDLGTDQ
                     VITYDLDQEGKLSKLYTYHSKPGAGSRHIIFHNHYKIAYLICELNSTIEVLIYDGVGE
                     FERMQVISTLPEAYEGFNGTAAIHLSKDGKYLYASNRGHDSIAVYTILADGSLELLEI
                     VPTHGQTPRDFDLTPDQKFLIVVHQDSDNATVFKRNCDNGRLAELSNDFHVPEAVCIR
                     FAP"
     gene            42115..43281
                     /locus_tag="ACL29Z_000612"
     CDS             42115..43281
                     /locus_tag="ACL29Z_000612"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000435446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015562 - efflux transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:1905887 - autoinducer AI-2 transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HGR0068963.1"
                     /translation="MEQKEKHFSLSWFFKWFLDNKAITVFLVTLLLGLNLFILSKISF
                     LFSPVLDFLAVVMLPVILSGLLYYLLNPIVDWMEKHKVNRVIAITIVFVIIALFIIWG
                     LAVAIPNLQRQVLTFARNVPVYLEDIDRIVNGLVAQHLPDDFRPQLEQVLTNFSSQAT
                     VLASKVSSQAVNWVSAFISGASQVIVALIIVPFMLFYLLRDGKGLRNYLTQFIPRKLK
                     EPVGQVLSDVNQQLSNYVRGQVTVAIIVAVMFIIFFKIIGLRYAVTLGVTAGILNLVP
                     YLGSFLAMLPALVLGLIAGPVMLLKVVIVFIVEQTIEGRFVSPLILGSQLNIHPINVL
                     FVLLTSGSMFGIWGVLLGIPVYASAKVVISAIFEWYKVVSGLYELEGEEVKSEQ"
     gene            43271..44500
                     /locus_tag="ACL29Z_000613"
     CDS             43271..44500
                     /locus_tag="ACL29Z_000613"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864303.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005515 - protein binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tetratricopeptide repeat protein"
                     /protein_id="HGR0068964.1"
                     /translation="MNNSQQMLQALEEQDLTKAEHYFAKALENDSSDLLYELATYLEG
                     IGFYPQAKEIYLKIVEDFPEVHLNLAAIASEDGQIEEAFTYLEEIQADSDWYVSSLAL
                     KADLYQLEGLTDVAREKLLEALTYSEDSLLILGLAELDSELENYQAAIQAYAQLDNRS
                     IYEQTGISTYQRIGFAYAQLGKFETATEFLEKALELEYDDLTAFELASLYFDQEEYQK
                     ATLYFKQLDTISPDFEGYEYGYSQALHKEHQVQEALRIAKQGLEKNPFETRLLLAASQ
                     FSYELHDASGAENYLLTAKEDAEDTEEILLRLATIYLEQERYEDILELQSEEPENLLT
                     KWMIARSYQEMDDLDTAYEYYQELTGDLKDNPEFLEHYIYLLRELGHFEEAKVHAHTY
                     LKLVPDDVQMQELFERL"
BASE COUNT        13551 a         8245 c         9899 g        12812 t
ORIGIN      
        1 ctaagggtga caaaggtgaa cgcggagaag atggtaagac tccagaagta actgtaactc
       61 caggtaaaga tggccatagt actgacatta cattcactgt tccaggtaaa gatccagtta
      121 cagtaaatgt taaggacgga gaaaatggtc tgaacggtaa aactccaaaa gttgatttac
      181 ttcgtgtcca aggaaaaaac ggaaatccat ctcatacagt tgtgacattc tatacagatg
      241 aaaacaatga cggcaaatat acaccaggaa ctgatgaact tctaggttca gaaatgatta
      301 aagatggtgc taaaggcgcg gacggacgag atggtaaatc attgcttact gtcaaggatg
      361 gtaaagaaac taaagtttac caagaagatc cagctaaccc aggacaacca ttaaatccag
      421 aaaaaccact tgcggtaatt agagatggag tagatggaaa atcacctaca gttacagctg
      481 ttcgtaaaga tgaagcaggg cataaaggtg tagaaatcac tgttgataac catgatggtt
      541 cacaaccaac tacagtcttt gttcaagatg gtgctaaggg aaaaactggt gcaaccggtc
      601 aggatggaca aactcctaca atcactactc aacgtggaca agatggccaa agcactgttg
      661 taactatcac aacatcaggt aaagatccag taaccttcac tgtaaaagat ggtaagaatg
      721 gtaaagatgg ccgtgcaccg aaaatcaaag tagaagatat tacttcacct tcaagaatta
      781 gacgcgatac agatgctgct gcaactccaa cgcgtaacgg tatccgtgtt acagtttatg
      841 atgatgttaa tgacaatggg gtatacgacg aaggtgtcga taaagtatta aatagtaaag
      901 atatttataa cggtatagat ggacgtgatg gttcagctcc aactattact acaaaagata
      961 atggagatgg aactcacact atcacagttc aaaacccaga tggttctgaa tcaacaacag
     1021 ttgttaaaga tggtaaagac ggtaaaactg cgaatatcac tacaacagaa aacccagatg
     1081 gaagccacac aattacggtg acaaatccag atggttcaac taaagaaact gttgttaaaa
     1141 acggtaaaga cggtaagact cctaaagttg aagtaacgga taacaacgat ggaactcata
     1201 ctgttaaagt tacagatgga gacggcaatg ttaccaacgc tatcatcaaa gatggtaaag
     1261 acggtaaagc tgcaacagca acaactactg aaaatccaga tggaagccac acagtaacaa
     1321 tcactaaccc agacggaact aagaatgagt ttgttgttaa gaatggacgt gacggtgttg
     1381 acggacgtac tccaaccgca tctgttcgtg ataatggaga cggaagtcat acaatcgtta
     1441 ttacaaatcc agaaggtgtg acaactgaaa ccacagttcg tgatggtaaa tcaccaaaag
     1501 tgactataac tgatgaacaa aatggaactc ataagatctc tgttctaaat ggtgacggaa
     1561 caactactga aacaatcatt aaagatggta aatcaccagt agcaacagtt agagataacc
     1621 aagatggtac ttacactatt cgtgtggaaa acggtaatgg cactgtttct gaaaccacag
     1681 ttcgtgacgg taaatcacca actgctaagg ttgtggataa cggagatgga actcacacta
     1741 tcacagttgt gaactcagac ggaacaacta caacaactac agttcgtgat ggtagagaac
     1801 caaaacttga agttattgat aacaacgatg gttcacacac tattaaagtg acaggtgctg
     1861 atggtaaaga aacgacaact acaatctttg atggtaaatc accaaaagcg aacatcgttg
     1921 ataacggaga tggaactcat acattaacaa tcgtagattc tgatggtcgt gaatacaaat
     1981 ctattattaa agatggtaaa gacggcaaag atggcgtttc accaactgta actgttgaaa
     2041 ataataacga tggaactcac gttgttacaa tcactaatcc agatggaagt aagacagaaa
     2101 tggtgattaa agacggtaaa gatggtaaat caccaaaagt ttctgttgaa gataatggtg
     2161 atggtagtca tacaatcaca atcatcaatt ctgatggaac tgtgacaaaa acagttatta
     2221 aagatggcaa agatggtaga gatggacgtg atggtcgaga cggcaaagac ggcaaagatg
     2281 gaaaatgtgg atgccaagac aaaccagtaa caccatcaaa tgacaaacca gttcctccaa
     2341 caccaaatgt gccgacacca gaagtaccgg ttaaacctgt gccagcgcaa ccaacaccaa
     2401 atgtaccgac accagaagtg ccagtacaac caactccagc agttccaaca ccaaatgtac
     2461 cggttccaaa acaaccagta gtaccaacac cggctcaacc agcaactcca gtaaatgcta
     2521 atccagtagc accaactaca ggtaaagaaa accgtgggga caaattacct gaaactggaa
     2581 gccaatctga ttatatctct gttcttttag gtagcggtat tctattgagc ctatatgtag
     2641 gacgaagaaa agaagattaa tcagccaaaa gcagtcacta atttctcgaa agaagatgat
     2701 aagtgataga tctcgaatga aagaatattc ttagaatgat tttcctatga tggaaaagac
     2761 tgctaaaaac cttgagtggt aacgctcaag gtttttttgg atggctgatg tttgtctgaa
     2821 aatcttgatt gagaaataaa aagccaccct attaggtggc tataattgat ttagactttc
     2881 taaaattttc tattttttac tgaatcgctt cgaccaagtc ttgagcttgt ttttcaagtg
     2941 agtttaggac tgtttcttca agaaccaatt ttccgtctgc ccaggcagag tcattaacac
     3001 gtgcagcagt gaaatcacca acgccttgtg tacggataaa tggcaagagg tctttgtaga
     3061 tagcgaaaag ttgatcgtgc cctgcattgg ctacagatga tactgtgaca aacttgtctt
     3121 gaagggcaga agcgccacgt gtatcagaca agtcaagggc acgagatagc cagtcaagca
     3181 agttttttac tgtaccaggg atagagaagt tgtagactgg agagaaaatc cagatagcat
     3241 ccgcaacgag aactgcttca cgagcagcag ctacagctgg atgtgttgga acttccaaat
     3301 cttggctgaa gagaggaagg gctgaataat caaggtagct aacttccgct ttaccagcaa
     3361 gtgctttctc agcttcgagc gccatttggt ggttgaaaga accttgacgt agtgatccga
     3421 cgataaataa tactttttta gacatgatgt gtctcctttt tcttcaaatt tcgagaactc
     3481 tctcgttgtt ataaaacata ttacaacaaa acaaaagaac ttgcaagaaa tttgctcaga
     3541 gtttatttga aaattgtaaa atttcggaaa ctctagtcat ttgtgactga aaaagtaaga
     3601 actgtttcac tttcaaaatc ggttttgttt gaagggagaa atagaattgg ttgctcaaag
     3661 cacagctttg aggttgcaga taaagctgac gtggtttgaa gagattttcg aagagtattc
     3721 ttatattcac ttgtaataaa gcttaataga tggtaaaata gacgagtgaa aaaaagacaa
     3781 aacaaagcaa aaaataatct actgtggcag tatggtctag ggatgacgat tttgtttgtg
     3841 gttatcagtg gttcctttct gtatatggtt tctcttagca tgaaacccta tcaaacagct
     3901 aaaagtgaag gagaaaaatt agctcagcag tatgcaggat tagagcaggc tgttcaggtt
     3961 gatttataca atggcttgga atcttattac agcgttcttg gtcgtaataa acagcaagaa
     4021 gcgcttgctg tcctgattgg taaagatgac cataagattt acgtttatca gctaaatcag
     4081 ggtgtttcac aagaaaaagc agaaacggtt tctaaggaaa agggagctgg cgagattgac
     4141 aagataacct ttggccgtta tcaagataag ccaatctggg aagttaagtc aggatctgat
     4201 ttttatctag tagattttga aacaggagca ttggtcaaca aggagggcct atgaaattat
     4261 ccaaccgtgt tttagaaatg gaagaaagtg tgactttggc tgctggagcc cgtgccaaag
     4321 cactgaaggc tgagggtaga gatattttgt ctctaacctt gggtgagcca gatttcacta
     4381 ctcccaaaaa tatccaagat gccgccattg catcgattcg agatgggcgt gcttcttttt
     4441 atacagtaac ctcaggtctg ccagagctta aggcggcggt caatagctac tttgagcgct
     4501 tttacggcta ttctgtagcg tcaaatcaag tgacagtcgc tgcgggagcc aaatattctc
     4561 tctatacctt ctttatggct gtggtcaatc caggtgatga agtcatcatc ccaaccccat
     4621 actgggttag ctatggagat caggtcaaga tggcagaagg cgttcccgtc tttgtttctg
     4681 ctaaggaaga caatcacttt aaggtgaccg tggagcagtt agaagcagct cggactgaca
     4741 agaccaaggt tttggtgctg aattcgccat ctaatcccac aggtatgatt tacacccgtg
     4801 aggaactctt ggcaattgga aactgggctg tagaaaatga tattctcatc ctagcagacg
     4861 atatctatgg ccgcttagtt tataatggtc atgagttcac accgatttct agcctatcgg
     4921 aagcgattcg caagcaaaca gtggtcatca atggtgtgtc taaaacctat gccatgactg
     4981 gttggcggat tggttatgcc gttggagaag cagacattat cgctgccatg tccaagattg
     5041 caggtcaaac aacttcgaat ccgtcagcag tagcccaata tgcagcagtt gaggctctat
     5101 caggtgagca agatactgta gaaagcatgc gtcaggcctt tgaggaacgt cttaatacta
     5161 tctatcccct ccttgcagag gtgccaggat ttgaagtggt caaaccgcaa ggggccttct
     5221 atctcttccc aaatgtcaaa aaggccatgg agatgaaagg ctacacggat gtgacagact
     5281 ttacaactgc tatcttagaa gaagccgaag tggccttggt aacaggagct ggatttggag
     5341 caccagaaaa tgtccgcctc agctatgcga cagacctaga cacgcttaaa gaagcagtcg
     5401 aacgcttgaa agcatttatg ggtagtgaga atgattgatc attttgagat taaggtaaag
     5461 gatttacaaa tttcagaagg attttatagg agttttctcg ctcctttgga ctataaaatg
     5521 gcttttaaga ctagttctct aattagtttt ctatccccga acagccctca tcctggtggt
     5581 gatttttggc tgactcaggg aacacaagat cctgttcatt ttgctttttt agcagaaaat
     5641 aaggaagaag ttcaggcttg ttatgaggct ggcatagagg caggtgggcg agacaatggg
     5701 gttcctggtt atcgaagtga gcatccgatt tactatgctg cttttatgat tgacctggat
     5761 gggaacaata tagaggtggt ttgccataaa gaataaaaaa gaaaaggaaa aataatgaca
     5821 aaacgtgtaa cgattattga cgtaaaagac tatgttggtc aggaagtgac gattggcgct
     5881 tgggttgcca acaaatcagg aaaaggaaaa atcgctttct tacaattgcg tgatggaaca
     5941 gccttctttc aaggtgtggc ttttaaacca aactttgtcg aaaaatttgg tgaagaagtg
     6001 ggacttgaga agtttgatgt tatcaaacgc ttgagccaag aaacgtctgt ttatgtgaca
     6061 ggtattgtca aagaggacga acgttctaaa tttggctatg agttggacat cacagacatc
     6121 gaagtgatcg gtgaatctca agactaccca atcacaccaa aagaacacgg aacagacttt
     6181 ttgatggata accgtcactt gtggctacgc tctcgtaagc aagtagctgt gttgcaaatc
     6241 cgtaacgcta ttatctatgc aacttatgag ttctttgaca agaacggttt tatgaagttt
     6301 gacagcccaa ttctttcagg aaatgcggca gaagattcta cagaactctt tgaaactgac
     6361 tacttcggaa cgccagccta cttgagccaa tcaggtcagc tttacctaga agcaggggct
     6421 atggctcttg gtcgtgtctt tgactttggt ccagttttcc gtgctgaaaa atcaaaaaca
     6481 cgccgtcact tgactgagtt ctggatgatg gatgctgagt actcatactt gacacatgat
     6541 gagtcgcttg acttgcaaga agcttatgtg aaagctcttc tacaaggtgt tcttgaccgc
     6601 gcgcctcaag ccttggaaac cttggaacgt gatacagaac tcttgaaacg ctacattgca
     6661 gagccattca aacgtatcac ttacgatcaa gccattgacc tcttgcaaga gcatgaaaat
     6721 gatgaagatg ctgactacga gcatcttgag catggtgatg actttgggtc accacacgaa
     6781 acttggattt caaaccactt tggtgtgcca acatttgtca tgaactatcc agcagccatc
     6841 aaggccttct acatgaaacc agttcctgga aatccagagc gcgtgctttg tgcagacttg
     6901 cttgctccag aaggctatgg agaaattatc ggtgggtcta tgcgtgagga agattacgat
     6961 gcccttgtcg ctaagatgga tgaacttggc atggatcgta cagaatatga attctacctt
     7021 gaccttcgta aatacggtac agttccacac ggaggatttg gtatcggtat cgaacgtatg
     7081 gtaaccttcg cagcaggaac aaaacatatc cgtgaagcta ttccattccc acgtatgttg
     7141 caccgtatca aaccataaga acaggaaaac gcccatgtgg cgttttttcg aattctagtg
     7201 tttttacttg cgtaaaaaaa ttttttctag tataatagtt tattgtgagc gaacctcact
     7261 taccccttgc aaagtcttgg ggtcattaga ccaaaaggag gaacatatca atggctaaat
     7321 acgaaattct ttatatcatt cgtccaaaca ttgaagaaga agctaaaaac gctttggtag
     7381 cacgttttga ctctattttg actgacaacg gtgcaactgt tgttgaatca aaaacttggg
     7441 aaaaacgtcg tcttgcatac gaaatccaag atttccgtga aggactttac cacatcgtta
     7501 acgttgaagc aaatgacgat gcagctctta aagagtttga ccgtctttca aaaatcaacg
     7561 ctgacattct tcgtcacatg atcgtcaaaa ttgacgcgta agaaggtaaa ctatgattaa
     7621 caatgttgta cttgtagggc gtatgacacg tgacgctgag ttgcgttata ccccatcaaa
     7681 tgtagcagtt gcgactttta ctcttgcagt aaaccgtaca tttaagagtc aaaatggtga
     7741 acgtgaggct gattttatca atgtcgttat gtggcgccaa caggctgaaa atcttgctaa
     7801 ctgggctaaa aaaggctcac ttatcggggt gacaggtcgt atccagactc gtagttacga
     7861 taaccagcaa ggacaacgtg tctacgtgac agaggtcgtg gctgagaatt tccaaatgtt
     7921 ggaaagccgt agtgtgcgtg agggtcacac aggtggagct tactctgcac caactgcaaa
     7981 ctattcagca cctacaaatt cagtaccaga cttttcacgt aatgaaaatc catttggagc
     8041 aacaaaccca ttggatattt cagatgatga tttaccattc taatggacaa ctaaacttat
     8101 aaaggagaaa aaacatggct caacaacgtc gtggcggatt caaacgccgt aaaaaagttg
     8161 attacatcgc agcaaacaaa attgaatatg ttgattacaa agatactgag cttcttagcc
     8221 gtttcgtttc agaacgtggg aaaatccttc ctcgtcgtgt aacaggaact tcagctaaaa
     8281 accaacgtaa agtaacaaca gctatcaaac gcgctcgcgt aatggctttg atgcctttcg
     8341 taaacgaaga ttaaagaaaa gacccagttg ggtctctttt tcatgagctt gaaaacaaga
     8401 aagcgaatta agatcctaac gggtcttttt tcacaagctt tgaaatgaga gagcgagtta
     8461 ggctcagtgg ctcccttttt acgagtttga aaacaagaga acacattaaa agcacgatgg
     8521 agctttttca taaatatgtc tcttttctca tccaagaaat taaaataaaa atgataaact
     8581 ttttgaaaat aggggatttg cctactttat gatataatgg aaagagttag attgaaagag
     8641 gtagtgagat ggacgcgaaa ttaagataca aggcaaagaa gatcaagatt gtcttttttg
     8701 atattgatga tacattgcgg aattcaaaga cagggtttat tccaactaca attcccactg
     8761 tttttaaaca gttgcgtgaa aaaggaattt taacaggaat cgcctctgga cgtggcattt
     8821 ttggtgttgt tccagagatt cgtgatctca agcctgactt ttttgtaact ttgaatgggg
     8881 cttatatcga agataaaaaa ggtcaggtca tttatcagca tcagattgaa aagtcagatg
     8941 ttgaggagta tatctcttgg gctaagcaag aaggaattga gtatggcttg gttgggagtc
     9001 atgatgccaa gttgtcgact cgcaccgata tgatgagtga agctatcaat ccaatttatc
     9061 ccgacttaga tgtagatccc gatttccatg aaaaagaaga tatctatcag atgtggactt
     9121 ttgaagataa gggagatgac ttgcacttgc ctgacagtct ctcagacaaa cttcgcatgg
     9181 ttcgttggca tcaacattcg tctgatattg tgccgatttc aggctccaaa gcgacggggg
     9241 tggaaaaggt tgtggaacac cttggcttga aaccagagaa ggtcatggtt tttggagatg
     9301 gtctcaacga cttggaactc tttgattatg ctggaatcag cgttgccatg ggaatttctc
     9361 atgataaaat caaagaaaaa gcagattata ttacaaaaac attagaagaa gatggcattt
     9421 ttgctgcctt agaagtattt ggtatggtag aaaaagaatt gcattttcca caagtagaca
     9481 ttgaaacagt agaaggtcct cttgcgacta ttaagaccaa tcacggagac ttacgtatca
     9541 agcttttccc tgaacatgct cctaaaacag tggctaactt tgtatctctt tcaaaagatg
     9601 gctactatga tggtgtcatt ttccaccgta ttatcaagga ctttatgatc caaggtggag
     9661 acccaactgg aactggtatg ggtggccagt caatctacgg cgaatctttt gaggatgaat
     9721 tctcagaaga gctttacaat atccgtggtg ctctttccat ggcaaatgct ggtccaaata
     9781 ccaacggcag ccagttcttt atcgtgcaaa accaacacct accttattct aagaaagaaa
     9841 ttactcgtgg tggttggcca gaaccgattg cagaaatcta tgccaatcaa ggtgggacac
     9901 ctcacctaga ccgtcgtcac acggtttttg gtcagttagc tgatgaagca tcttacgctg
     9961 tcttggatgc cattgctgct gttgagacag gagctatgga caagccagtt gaagatgttg
    10021 taattgaaac tattgaaatc gaggactaag atgaaaatcg gtgataagct aaaggggcgt
    10081 attacaggga ttcagcccta cggtgccttt gttgagttag agacgggtga tacggggctg
    10141 attcacattt cagaaattcg gacaggattt attgaaaata ttcatgaaac cttgaaagtc
    10201 gatgaagagg ttcaagttca ggtagtggat ttagatgaat ttacggggaa agccagtctt
    10261 tctatccgca ctttggagga agaaaagtac cagtttccta gacggagacg cttttcaagc
    10321 gaccgcttta actacggttt tgctcccttt cgacgaatgc taccaatctg gactggagaa
    10381 gccctgcacc atttaaaaaa gaagaagtag tttagagttt tatatttttt gtaatgttaa
    10441 tataaatttg ctataatagg accatggaag aagaacaatt attaaaatca ggagagcgca
    10501 ttaaccagct cttttcgaca gatatcaaaa tcattcaaaa tagagaggtt tttagctatt
    10561 cggtggatag tgttctctta tcacgatttc cacgttttcc taagaagggg ttgattgtgg
    10621 atttttgtgc tgggaatgga gcagtggggc tttttgctag cactcgtact caagcacaga
    10681 tattgtctgt tgagattcag gagcgtttgg cggatatggc tgaacgctct gtccgtttga
    10741 atggattaga ggagcaaatg caggtcatct gcgatgattt gaaaaatatg cctgctcaca
    10801 ttcaggggag taaggtggat atgattttgt gtaatccacc ctatttcaag gtggatcctt
    10861 attctaatct gaacgagagt gaacattatc tcttggctcg acacgaaatc acgactaatt
    10921 tggaagaaat ctgtcgtagt gcccagagta ttctcaagtc taatgggcgt ttggccatgg
    10981 ttcatcgtcc tgatcgactt ctggatattt tggatacgtt aaaacgacat aatctagccc
    11041 ctaagcgcct gcagtttgtt tatccaaaaa gagaaaagga agccaatatg cttttgattg
    11101 aggcgatcaa ggatggctca acaagtggct ttaaggtctt acctcctttg attgtccaca
    11161 atgatgatgg ctcttatacg cccgaaatcg aagagattta ttatggatca taaggcttat
    11221 atgtacgttc tggagtgtcg tgatggatcc tactatatag gctatacgac tgatgtgaga
    11281 agacgcctcg ctatccacaa tagtgggaag ggagccaaat atacacgagc acgcttgcca
    11341 gtcaaactta tctatgctca aggttttgcc agtaaggaag aagccatgtc ggctgaagct
    11401 cttctcaagc gtaagaagag gccacagaag gaagaatttt tatctgaaaa tcaagataga
    11461 aatttactca gttattttga agaatcgtgg ggagtccttt gactcctctt acctttgtca
    11521 aaaagcgaaa aaaatgctac aataaagaaa ataaacaaaa tgaggtatta tcatgtccaa
    11581 gattctagta tttggtcacc aaaatccaga ctcagatgcc atcggatcat ctgtagcttt
    11641 tgcctacctt gcaaaagaag cttacggttt ggatacggaa gctgttgccc ttggaactcc
    11701 aaatgaagaa acagcctttg tcttgaacta ttttggtgtg gaagcaccac gtgttatcac
    11761 ttctgccaaa gcagaggggg cagagcaagt tatcttgact gaccacaatg aattccaaca
    11821 atctgtatca gatatcgctg aagtagaagt ttacggtgtt gtagaccacc accgtgtggc
    11881 taactttgaa actgcaagcc cactttacat gcgtttggag ccagttggat cagcgtcttc
    11941 aatcgtttac cgtatgttca aagaacatgg tgtagctgtg cctaaagaga ttgcaggttt
    12001 gatgctttca ggtttgattt cagataccct tcttttgaaa tcaccaacaa cacacccaac
    12061 agataaaatc attgctcctg aattggctga attggctggt gtgaacttgg aagaatatgg
    12121 tttggcaatg ttgaaagctg gtaccaactt ggctagcaaa tctgctgaag aattgattga
    12181 catcgatgct aagacttttg aactcaacgg aaataatgtc cgtgttgccc aagtgaacac
    12241 agttgacatc gctgaagttt tggaacgcca agcagaaatt gaagctgcaa tgcaagctgc
    12301 caacgaatca aacggctact ctgactttgt cttgatgatt acagatatcg tcaactcaaa
    12361 ctcagaaata ttggctcttg gtgccaatat ggacaaggtc gaagcggctt tcaatttcaa
    12421 acttgaaaac aatcatgcct tccttgctgg tgccgtttca cgtaagaaac aagtggtacc
    12481 tcaattaact gaaagcttta atgcgtaaga ttttgggtgt cagctcaaaa tcggaaagtc
    12541 tagtttgcct tatatcgaaa ggagtttcgg ctcctttttt tctaggagtg aagtatgtta
    12601 gaaaatggcg atttgatttt tgtgagagat gggtcagaca tgggacaggc catccagact
    12661 tccacaggta actatagcca tgttgccatt tatttggatg ggatgattta tcatgctagt
    12721 ggacaggctg gtgttgtctg tcaagaaccg gcagacttct ttgagtccaa tcatttgtac
    12781 gacctctatg tttacccaga aatggatatc cagtcggtga aggaaagagc ttgcagacat
    12841 cttggagcac cctacaatgc ttctttctat ccagatgcag ctggtttcta ctgctcccag
    12901 tatatagcag aaatcctacc tatttttgaa actattccta tgaaatttgg agatggggaa
    12961 caggagatta gtgatttttg gagggagtat tacatagaac taggtctgcc tgttcctctg
    13021 aaccaagctg ggaccaatcc tagtcagttg gcagcatcgc ctctgttaca atgtaaagaa
    13081 aggaatcttc atgattcaga tttttaatcc atctcgtttg acgagacagc catttttgga
    13141 gaattgatcc gctatctgga ccagtatgag gatgtgattc tacgggaaat taaggctcaa
    13201 tttccagatg ttgcagttga taaactcatg gaagagtata taaaggcaag cttgattcta
    13261 cgtgaaaata agcgctatta ccttaatttt cctacgcttg aatcacttga tagtcttgaa
    13321 ctggatcaag agatttttgt cagagaagct agtccggtct atcaagcctt gttggagcag
    13381 agttttgaga cggaattgcg caatcaaatc aatgcagcta ttttagttga aaagacggac
    13441 tttgcgcgca ttaaaatgac cctgtccaat tatttttaca aggtcaaaca gcagtatcct
    13501 ttgacagaaa aacagcagga gctctatgac attttaggag atgttaatcc tgagtatgcc
    13561 ctcaagtata tgacggcttt tttgttgaaa tttctcaaaa aagaccagct tatgcagaaa
    13621 tgccgtgata tctttgtgga cagtttggtt gtcttaggct atattgtgca aaatgaagat
    13681 ggaaagtatg agttggctat cgattttgat aaggagagat taactttcta cttagcgtga
    13741 tttcttgttt ctgagtacat tgtttgactt tccttagtat tcggtataaa ctatatgtaa
    13801 ccggtaacac atatcggaat aaactaaagg agacaatcat atgtcacttg aaaacaaatt
    13861 ggaacaagca acaggcgctg tcaaagaagg ttttggtaaa gttactggag acagcaagac
    13921 agaacttgaa ggagctgttg aaaaaacagt tgctaaggca aaagacgttg tagaagacgc
    13981 aaaaggtgct gtagaaggtg ccgttgaagg tttgaaaaac gtttttacta aataatagga
    14041 aaaaatcaag ggtttcattt tcccttgatt ttttctattc ttataaataa ttttctgcga
    14101 cggctgtatc tcctgggtag gattctttct tgccctggat gatttggtaa caatcggctc
    14161 ccttacccgc aataataact gcatctaatt cgtgatttgt gatagccatt gccgccttga
    14221 tggcttcttg gcgatccgca atcttttcaa caggatgatt gatgtagcta ctaatttcat
    14281 ctgcaatggc cattgggtct tcatagttag ggtcatcagc agtcagaaag acttgaatct
    14341 cagggtgttg attgaggagg aggccaaagt ccttacgacg actttctccc ttgtttcctg
    14401 ttgatcccag aaccagagca atctttccgg tttgatgagt ttcaaccaca ttgatgagtt
    14461 ttttcagact atccccattg tgggcatagt cgatgaagac cttggctcca tttttctgag
    14521 tgaggacttc catacgacca ggaacgcggg ttgcagcgat gccttttttg atgtcctcaa
    14581 gacttgctcc gagacggata caagcaagtc cagcagcaac tgcattttct tggttgaagt
    14641 tgccaatgag ttggatatca taatctccag cgagtttacc cgtagctgaa aagctaaagg
    14701 ctttggaatt ctcgatttgg ttatcaaatt ggctaccata gaaatcatgg tcttgatctt
    14761 caacctgttc tttcaagact gagaagtggt ccatgtcact gttaatgatg actgctcggc
    14821 tattttccat caagagacgc ttgtggtaga aatagtcttc aaagctaggg tgttcaatcg
    14881 ggccgatatg gtcaggagtg atgttaagaa agactcctac atcaaaggtc agtccataga
    14941 ctcgatggac tagataggct tgactggaga cttccatgat gaggtgggta cggtcatttt
    15001 gcacagcctg attcatcatg tcaaagaggt caatactctc aggggttgtc aacgctgact
    15061 taaagaaagt ctcgccatca agagttgtgt tcatggtcga caacatagca ggtctatgcc
    15121 cttgagataa gatgttatag gcgaaatagg ttgctgttgt cttaccctta gtaccagtaa
    15181 aggcaaggag tttgagtttc tcttgtggat taccatagaa ctccatggca atcaaactca
    15241 tggctttctt tatatcgttc acaatgatga cagggatatc gacttcgtag tccttttcag
    15301 ctacatacca agctaaacct tgtgttatag cagaaagaag gtattctttt ttaaaggcag
    15361 cgccttttgc aaaaaaaaga gtgtcttctg ttacttttcg gctgtcgtag ctgatgctat
    15421 caaaaataac tttgctgtag ttgtagtggt aatgaccttg gtcaataatt tcgcgaaaaa
    15481 ggccatcttt ctttaaaata tctaatacgg tttcaatctt aatcatactt tctattgtaa
    15541 accgaaagtc gtaaatttac aagtaacaag gaaaagttta taatggaaga taaggagttt
    15601 ttcctagtta tcaaaattga atgaggaatc tatgtcgcac gaaaacaatc accagcaggc
    15661 ccagatgtta cgggggactg cttggctaac ggctagtaac tttatcagtc gcctactcgg
    15721 ggctgtttac attatccctt ggtacatctg gatgggggct tatgcagcta aggcaaatgg
    15781 tctctttacc atgggttaca atatctatgc ttggttcttg ttggtttcaa cagcggggat
    15841 tccagttgcg gtggccaagc aagttgccaa gtataatacc atgcgagaag aagagcatag
    15901 ctttgccctg attcggagct tcttaggctt tatgacagga ctaggcctgg tttttgcttt
    15961 agtcttgtat gtctttgctc cttggctagc agacttgtct ggcgtgggca aagacttgat
    16021 cccaatcatg caaagcttgg cttggggagt cttgattttc ccgtctatga gtgttatccg
    16081 aggatttttc caagggatga ataacctcaa accctatgcc atgagccaaa ttgctgagca
    16141 ggtcattcgt gttatctgga tgctcctagc aacctttatc attatgaagc tcggttcagg
    16201 agattatcta gcagccgtta cccaatcaac ctttgctgcc tttgtcggta tggtagccag
    16261 ttttgcagtc ttgatttatt tccttgccca agaaggttca ctcaaaagag tctttgaaac
    16321 aggagataag attaacagta agcgtctctt ggttgatacc attaaggaag ccattccttt
    16381 tatcctgaca gggtctgcca tccagctctt ccagattttg gatcagctga cctttatcaa
    16441 tagtatgagc tggtttacca actacagcaa tgaggacttg gttgtcatgt tttcttattt
    16501 ctcagccaat cctaataaaa tcacgatgat tttgatttct gtaggggttt cgattgggag
    16561 tgttggtttg ccacttttga cggaaaacta tgtcaagggg gacttgaaag cggcttctcg
    16621 tctcgttcag gacagtctca ccctactctt tatgttcttg ctaccagcaa cggttggagt
    16681 ggttatggta ggagaacctc tttatacggt cttctatggt aagccagata gtttggctct
    16741 gggcttattt gtctttgcag ttttgcagtc tattatttta ggcttgtaca tggtcttgtc
    16801 tccaatgctt caggccatgt tccgcaaccg caaggccgtt ctctatttta tctatggttc
    16861 tattgccaag ctagtcttgc aactacctac catcgccctc ttccacagtt atggtccttt
    16921 gatttcaaca accattgctc tcatcattcc taacgtcttg atgtatcggg atatttgtaa
    16981 agtaactggt gtcaagcgca aggtgatttt gaagcgaacc attttaatca gtttgctgac
    17041 cctagtcatg tttctgttaa taggaaccac ccagtggctg ttaggatttt tcttccaacc
    17101 aagtggacgt ttgtggagct tcttttatgt agctcttgtc ggtgccatgg ggggtgggct
    17161 ttatatggtt atgagtctgc gtacctattt attagataag gtaataggaa aagcccaagc
    17221 agatcgcctg cgagcaaaat ttaagctttc gtaaggtagc atttataaat aaaaggaata
    17281 agttgaacaa tcttttagga gaacttgaaa cttattcctt ttttagcgta aaaatagcta
    17341 aaattatctt tcaaaaatag aaaatgaggt ttttttcgat tttttggaaa aataattgac
    17401 taaacaaacc aaacgttgta taataaaaca aatatttaaa gcaggaggtt ctggaaatga
    17461 aaaagtctaa gagcaaatat ctaaccttgg caggtcttgt cctgggtaca ggagttttat
    17521 tgagcgcgtg tggaaattct agcacggcgt caaaaaccta caactatgtt tattcaagtg
    17581 atccatctag cttgaactat ctagcagaaa accgcgcagc aacatccgat attgttgcaa
    17641 atttggtaga cgggttatta gaaaatgacc aatatgggaa tattattcca tcattagcag
    17701 aggattggac tgtttctcag gacggtttga cctataccta caaacttcgt aaggatgcca
    17761 agtggtttac ttctgaggga gaagaatatg cgcctgtaac tgcccaggat tttgtgacag
    17821 gtttgcaata tgcagctgat aaaaaatcag aagccttgta tctagtgcag gactctgttg
    17881 ctggtttgga tgactatatc actggtaaaa caagcgactt ttcaactgtc ggtgtcaagg
    17941 cacttgatga ccaaacggtt caatatactt tggttaaacc agaactttac tggaattcaa
    18001 aaacacttgc aacgatactt tttcctgtta atgcagattt cctgaaatca aaaggggatg
    18061 attttgggaa ggcggatcca tctagtattt tgtacaatgg acctttcttg atgaaagcac
    18121 ttgtctcaaa atctgctatt gaatataaga aaaaccctaa ttactgggat gctaagaatg
    18181 tctttgtaga cgatgtgaaa ttgacctact atgatggtag cgatcaagaa tcactggaac
    18241 gtaattttac agctggtgct tatactacgg ctcgtctttt tcctaacagc tccagctatg
    18301 aagggattaa agaaaaatac aaaaacaata tcatctatag tatgcaaaat tcaacttcat
    18361 atttctttaa ttttaaccta gataggaagt cttacaatta tacttctaaa acaagtgaca
    18421 ttgaaaagaa atcgactcag gaagcagttc tcaataaaaa cttccgtcag gctatcaatt
    18481 ttgcttttga cagaacatct tatggggctc agtctgaagg gaaagaaggt gcaacaaaga
    18541 ttttgcgtaa cctagtggtt cctccaaact ttgtcagtat caagggaaaa gactttggtg
    18601 aagttgtagc ctctaagatg gtcaactatg gtaaggaatg gcaaggtatc aactttgcgg
    18661 atggtcaaga cccttactac aatcctgaga aagccaaggc taagtttgcg gaagctaaga
    18721 aagaactcga agcaaagggt gttcaattcc caatccactt ggataagact gtggaagtaa
    18781 cagataaagt aggcatacaa ggagttagtt ctatcaaaca atcaattgaa tctgttttag
    18841 gttctgataa tgtagtgatt gacattcagc aattaacatc agatgagttt gacagttcag
    18901 gctactttgc tcaaacagct gctcagaaag actatgattt atatcatggc ggttggggac
    18961 ctgattatca agacccgtca acctatctcg atatttttaa tactaatagt ggaggagttc
    19021 tacaaaatct tggactagag cctggagaag ccaatgacaa ggctaaggaa gttggactgg
    19081 atgtctatac tcaaatgttg gaagaagcta ataaagagca agatccagcc aaacgttatg
    19141 agaaatatgc tgatattcaa gcttggttga ttgatagttc tttagttctt ccaagtgttt
    19201 cgcgtggggg aacaccatca ttgagaagaa ccgtaccatt tgctgctgcc tatggtttaa
    19261 ccggtacaaa aggggttgaa tcatataaat acctcaaagt acaagataag attgtcacaa
    19321 cagacgaata tgcaaaagcc agagaaaaat ggttgaaaga aaaagaagaa tccaataaaa
    19381 aagcccaaga agaattggca aaacatgtca aataaaatct aattgtagat aagtttgtgt
    19441 aagaagtctt tgtgcttaaa aacgcataat atcaggtata taaaatccta gatgttatgc
    19501 gttttgttat aggaagattt attagatttt atcctcaaat tgagttattc ccgactttat
    19561 ccgttgaaat attataagga gtatttatga aattaaaatt attaagagta gatactaagg
    19621 tgattatggg gagtttctta cttgttctgt ctagtctact tgctttgttg cttcccctta
    19681 tcttaaaggg tttaatagat gggagttcta ttgaaaatat aggttccaaa gtatttcaat
    19741 cgtttttgat ttttattggt caagccttgt tttcttctat tggttactat ctgtttagtc
    19801 aatcgggtga aaaaaagata gcaaaaatca ggaaaaaagt gacagagggg ttgatttatg
    19861 cagagaaatc cttctttgat aagagccaaa gtggggagtt gacttctgcc attgtcaatg
    19921 acacgagtgt cattcgtgag tttttaatta cgactttccc aaatattatt ctgagtttag
    19981 ttatggtact tggttccatt gtagtcttat ttagtcttga ttggaatctt tctctacttt
    20041 tattcatcac tcttccttgt atgatgttta ttatcttgcc cctttccaat atcagtgaaa
    20101 agtatagtcg tcgtttacag gaggaaatcg gatttttaac agggcaattg actgaaaaga
    20161 ttcaagaaca tgaattaatt aagactaacc aagcagagaa aagtgtacag gatgttttgg
    20221 ataattgtat tgaaagggta caaaacaatt cactgaaatc agataggatt acttcttttg
    20281 agaccccgtt tgctctctta tttatctttg cgactatagc tgtgatgcta acctatgggg
    20341 gttatcgggt cagcgcagga tatatatctg tgggaacctt ggtttcgttt ttaatttacc
    20401 tctttcaatt acttaatcct attagtaata tagctaattt tgtaactgtt tattctagga
    20461 gcaagggatc ttcagttgca ctggagaact tgcttgcagt tcctaaagaa aaatttgagt
    20521 gaggaaaatc ggtatcagga caagggttga attttaacca tgtctatttt ggttatgatg
    20581 aaaatcgacc tgtcttaaag gatattactt gttcaatttt caaggggcaa aaaattgctt
    20641 ttgttggacc atctggatca ggaaaatcaa cgattgtgcg tttgttagag cagttttata
    20701 aaccgctttc aggagatatt ctaatggagc aatcaagtat atatgatttt aacttaaaag
    20761 aatggagaag taaaatcgct tgggtttcac aaaataatgc agtcttatct ggcagtattc
    20821 gtgacaatct ttgtctcggt ttgaatcgct tagtaactga tgatgaattg atgaaagtgc
    20881 tagacttagt atcactaggt gatgagattc gctccatgaa agagggacta gatactgaag
    20941 ttggtgaacg cggacgattc ttgtcagggg ggcaaagcca aagacttcaa atagctagaa
    21001 cctacttaaa agatgctgaa attcttatat ttgatgaatc cactgctaat cttgatgcgg
    21061 attctgagta tgcgattatc agtatcctct attctgcatt aaaggagaag acggttgtga
    21121 ttatagcgca tcgtttgtca acggtaaaag atgtggattg tattttcttc ttagaggagg
    21181 ggaaaatcac tggctcagga actcataagg aactactgga aaatcatgag cgttatgctc
    21241 gttttgtgca ggagcaaatg atagagtgaa ggtgtctttt gagattcacc attttatagt
    21301 ctattaaagg gagcaggaaa aactcccttt ttatatagtt tgaaactata actagctctt
    21361 gaaaagaaga aaatgagttg atgaaaataa gtggtacaat agttactata gatttggagg
    21421 aattgtatga gcaaggaatt acacattaac acaattttag cacaagcagg gatcaagtct
    21481 gatgaggcaa caggtgcttt ggtgacacca cttcattttt caacgaccta tcagcatcca
    21541 gagtttggtc gatctactgg gtttgactat acgcgaacta aaaatccaac tcgtagtaag
    21601 gctgaggaag tcttggcggc tattgagtca gcagactatg ccctagcgac tagctcaggg
    21661 atgtcagcta ttgtactggc ctttagcgtc tttccagtag gaagtaaggt cttggcagtg
    21721 cgtgatcttt acggtggttc ttttcgctgg tttaaccaag tggagcagga aggtcatttc
    21781 cattttacct atgccaatac agaagaagag ttgattgccg agttagaaaa ggatgtggat
    21841 gttctctata tcgaaacccc aaccaatccc ttgatgttgg aatttgatat cgaaaaacta
    21901 gcaaaattgg ctcatgctaa gggtgccaaa gtggtggtgg acaatacctt ctatagccct
    21961 atctaccaac gtccgattga agatggagca gatatcgttc tccattcagc aaccaagtat
    22021 ctagcaggcc acaatgatgt cttggctgga gtggttgtga ccaatagttt agaactatac
    22081 gagaagcttt tttacaatct taatacaaca ggggcagtct tgtctccatt tgacagctac
    22141 cagttgcttc gtggtctcaa gaccttgtct cttcgtatgg agcgctcaac agctaacgcc
    22201 caagaagtgg ttgccttttt gaaggattct ccagcagtta aggaagttct ctacactggt
    22261 cgtggaggca tgatttcctt taaagtagcc gatgaaacac gcattcctca tattttgaac
    22321 agtctcaagg tcttctcttt tgcggaaagt ttgggcggag tggaaagtct tattacttat
    22381 ccaacgactc aaactcatgc tgatattcca gcagaagtac gccattctta tggtttgaca
    22441 gatgacctct tgcgtttgtc tattgggatt gaggatgcta gagatttgat tgcagatttg
    22501 cgccaagcct tagaaggata agacaaagat gggaaaatat gattttacaa gcctgcccaa
    22561 ccgtttaggg caccatacct ataaatggaa agaaacagaa acggatagtg aagttctacc
    22621 agcttggata gcggatatgg actttgtggt cttgcctgaa atccgccaag ccgtgcaaac
    22681 ttacgcagac caactggttt atggttatac ctatgccagt gaagacttaa ttaaggaagt
    22741 tcaaaagtgg gaagctacac aatacggtta caactttgac aaagaggctc ttgtctttat
    22801 cgagggtgtg gtaccagcca tctcaacagc tattcaaacc tttacaaaag aaggcgaggc
    22861 ggttttaatt aacacgcctg tctacccacc ctttgctcgc agtgtcaagt tgaataatcg
    22921 tagattgatt actaattcct tagtggaaaa ggatggtctg tttgagattg actttgacca
    22981 acttgaaaag gatttggtgg aagaggaggt taaactctat attctttgca accctcacaa
    23041 tcctggtgga cgtgtttggg aaaaagaagt gttggagaag attggccaac tctgccaaaa
    23101 acacggtgtt ttgttagttt cggatgagat tcaccaagat ttgaccctct ttggtcacaa
    23161 acaccagtct ttcaatacca tcaatcctgc cttcaaaaat tttgctatcg tcttgagcag
    23221 tgccactaaa acatttaata ttgctggaac aaaaaattcc tatgcagtca ttgaaaatcc
    23281 taagttgaga ctagctttcc agaaacgcct gttggccaat aatcagcatg aaatttcagg
    23341 cttgggttat ttggcgacag aagctgccta tcgatacggt aaagattggc tagaggaact
    23401 caagcaagtc tttgaagacc acatcaatta tgtggtggat ctatttggaa aagagactaa
    23461 aatcaaggtc atgaaaccgc aaggtaccta cttgatttgg cttgactttt cagcttatga
    23521 cctgactgat gaaacattgc aagagttgtt gagaaatgaa gccaaggtta tcctcaaccg
    23581 tggtttggat tttggagagg aaggaagtct ccatgcccgc atcaatatag ctatgcccaa
    23641 atctctgttg caagaagtct gtcagcggat tgtggctact tttgccaaac gttaaaaatc
    23701 cagccttcta ggagaaaagt cttcctagaa ggctattttc ataggcgaaa atatggtata
    23761 ataaaaagat aaggtaaagg tgaaaatatg gctaaattga ttccggggaa aattcgtatc
    23821 gaaggtgttg ccctttatga aactggtaag gttgatatca tcaaggaaaa gaacaatcgg
    23881 ctctacgctc gcgttgcaga agaagaactg cgctatagtt tagaggatga tttggttttt
    23941 tgtgcctgtg atttttttca aaagaggggt tactgtgtgc atttggcagc gctagagcat
    24001 tttctgaaaa atgatgagcg tggtcaggaa atcttgtgga gtctggaaga aggtcatgaa
    24061 gaaaaagagg ccgttgaaac caaggtgacc ttgggtggca agtttttgga tcgaatttta
    24121 tctccaaaat cagaatgcgc ctatgagtta tcagctgtgg gtcaggtgga agcaggaacc
    24181 aatcatatct tgtggactct gagaatcggc caaatcaata gccaaaaata ctatatcatt
    24241 cgggatattc cacttttttt aaggattgtc gagcagagaa agtcgtatat gattggcaag
    24301 atttatgagg agtctctttc ttgggaaacc tttgatgatg ccagccaaga acttttgact
    24361 ttcttgcacg gactaacgga ggaagggctg gttccagacc tctttttcca aaaccaaggt
    24421 cggcacctct ttttccctct gacctttttt gagcagggtg tgaatttact gatggccttg
    24481 ccccattttc aatttgacca tcaagtggat agctaccaaa ccctgctttt tcaggatatg
    24541 catgctgatg ccaatctatt tgcctttgca gtaacagaat actcggatta ttttgaaatg
    24601 gaaatcagtg agagtcctag ggtcaatgtc ttttatcagg gagcagtact tttccataaa
    24661 ggtcaggttt attttttaac agaccagcag atgcgtcttc tcaaggaaat taaagcgtta
    24721 cctgtgggtc aacaaggaaa gaaatacctg caatttgata gcagtgatcg agacaaattg
    24781 gcctcctgtc tgactctttt tatccagatg ggcaccgttt cagctccaga acgtctacaa
    24841 atcaaaactt ttgcgccctc tttttacttt gacagggaag aagataatcg gattcgttta
    24901 gaaattcagt ttgattatgg aaatagacag gtatctagcc gacaagagct agaagaatta
    24961 cccttttcaa gtgacgcaga cttagaagaa agaattttcc aagtctgttt ggctgcgggc
    25021 tttgaagccg attttcaatc ttggcgtcag gccttaaaag cggagtctgt ctatcatttt
    25081 tttcatgata tcattccagt ctttgaaaaa ctcgggcatg ttgacctatc agataaacta
    25141 gaagagcttt atagcctagc gagtcctcag gtgcagattg cctccaaggg aggtctcttg
    25201 gaaatccagt ttgattttca aaatattgcc caggaggaaa tcgaccaagc catgcaggcc
    25261 ttggttgcca atcaggattt ttatattgat tcgtctaatc aagtttactt tttcgatgaa
    25321 gaaaccaaga aaattcgcca aaatctacag gaactggggc aatttgaatt aaaagatggg
    25381 accttgcagg ctcggaaatc cttggcctac agtttagctc atctctttga agggcgagac
    25441 cgtgtttctt tttcacaaga attccagaat ctggcccagg atttgacgca tccagaggac
    25501 tttcctttgc aagcaactca ggtcaaggct gacttgcgag attatcagga aaagggaatt
    25561 ggctggttgc agatgctcca tcattatggt tttggtggga ttttggctga tgatatggga
    25621 cttgggaaaa cccttcagac cattgctttt ttgactagtc aagtgacaaa agaaagtcgg
    25681 gttttgattc tcgctccgtc gggtttgatt tacaactggg cagatgagtt tcagaaattt
    25741 gctccacagt tggatgtggc tgttgttcat ggtttgaaag caagtcgtga ggagattctt
    25801 gccgagagcc atcaaatcta tgtgactagc tatgccacct tccgtcagga cagtgagctt
    25861 tatcagggga tggcctttga cttccttttc ttagatgaag ctcaggtcat gaaaaatgcc
    25921 cagaccaaga ttgcccagac cttgagacaa tttgtggtgc cgtcggtctt tgccttgtca
    25981 ggaactccga ttgaaaacca tctgggtgag ttgtggtcta tttttcaaat cgtcatgcct
    26041 ggacttttgc caagcaagaa agaatttatg aaattgccag cagagcgagt ggctcagttt
    26101 atcaagcctt tcgtgatgcg acgcaagaaa gaagaagttc tgactgaatt gccagacttg
    26161 attgaggtgg tttataaaaa tgaactggaa gaccagcaaa aggctattta ccttgcccag
    26221 ttacaacaga tgcgagacca tctggctcaa gtgtcagaac aggaatttca gcgaagtcgt
    26281 gtggaaattt tatctggttt gatgcgcttg cgtcaaatat gtgacactcc tgccctgttt
    26341 atggaagatt atcagggagc cagcggcaaa ctagatagtc tccgagacct actggtacag
    26401 gtggcagacg gcggacaccg tgtcttgatt ttctctcagt tcaagggaat gttggaaaaa
    26461 attgaacaag aactgccaga cttgggcctg acttccttta aaattacggg ttcaacccca
    26521 gccaaggaaa gacaagacat gaccaaggcc tttaaccaag gagaaagaga tgcctttctg
    26581 atttccctca aggctggtgg ggtcggtctg aacctgacag gtgcagatac agtgatcttg
    26641 gttgaccttt ggtggaatcc tgcggtggaa gcgcaagcca ttggccgtgc ccatcggatg
    26701 ggtcaggaag aaacggttga ggtctatcgc ttggtgacca agggaaccat tgaagaaaaa
    26761 attcaggaac tccaagaaca aaagaaacat ctggtgtcac aagtattgga cggcacagag
    26821 tcacgtggta gtctgaccct agcagaaatt agagaaattt tgggaatttc tgaagccagc
    26881 acttgaaaaa tcaagacaat acgctataat gaagtgttga aaggaaatag aaaatgaaac
    26941 aagaacgatt tccattggtg tcagatgacg aggtcatgtt gactgaaatg ccagtcatga
    27001 atctctatga tgagtctgat ctgatcagta atatcaaggg tgagtatcga gataaaaatt
    27061 atttagaatg ggctcctatt gctgaagaaa aaccagtaaa accgattgaa aagcaagtcg
    27121 aaaaacctaa aaaggctcct ttaggggtta aaaaagaagg aaagagctat gcggaggtgg
    27181 cgcgtgaaga agcgcgtgcg gacttgaaaa agaaacgctc tgctaactac ctaactcagg
    27241 atttcagcct tgcgagacgt cattctcagc ccagtctagt tagacagggc aatcaaccga
    27301 cagctccttt ccaaaaggaa aatcctggtg aatttgtcaa atatagccaa aaattgaccc
    27361 agtctcatta tatcttggcg gaagaagttc attctatccc taccaagaat gaagaagtgt
    27421 cagcacctgc tccaaagaaa aacaattatg attttctaaa gaagagccaa atctacaata
    27481 aaaaaagtaa acaaacagaa caagaacgtc gggttgccca agagttgaat ctgaccagaa
    27541 tgacagaata ggggagaaaa catgtcaaag acatatcatt ttatcggaat taagggatca
    27601 gggatgagtg ccttggcctt gatgttgcac cagatggggc acaaggttca gggatcagat
    27661 gttgaaaagt actactttac ccaacgcggt cttgagcagg caggaattac cattcttcct
    27721 tttgatgaaa aaaatctaga cggtgatatg gaaattatcg ctggaaatgc ctttcgtcca
    27781 gataacaacg tcgaaattgc ctatgcggac caaaatggta tcagctacaa acgttaccat
    27841 gagtttctag gtagctttat gcgtgacttt gttagcatgg gagtagcagg agcacatgga
    27901 aaaacttcaa cgacaggtat gttgtctcat gtcttgtctc acattacaga taccagcttc
    27961 ttgattggag atgggacagg tcgtggttcg gccaatgcca aatattttgt ctttgaatct
    28021 gacgaatatg agcgtcactt catgccttac cacccagaat actctattat caccaacatt
    28081 gactttgacc atccagatta tttcacaagt ctcgaggatg tttttaatgc ctttaacgac
    28141 tatgccaaac aaatcaccaa gggtcttttt gtctatggtg aagatgctga attgcgtaag
    28201 attacgtctg atgcaccaat ttattattat ggttttgaag ctgaaggcaa tgactttgta
    28261 gctagtgatc ttcttcgttc aataactggt tcaaccttca ccgttcattt ccgtggacaa
    28321 aacttggggc aattccacat tccaaccttt ggtcgtcaca atatcatgaa tgcgacagcc
    28381 gttattggtc ttctttacac agcaggattt gatttgaact tggtgcgtga gcacttgaaa
    28441 acatttgccg gtgttaaacg tcgtttcact gagaaaattg tcaatgatac agtgattatc
    28501 gatgactttg cccaccatcc aacagaaatt attgcgacct tggatgcggc tcgtcagaaa
    28561 tacccaagca aggaaattgt agcagtcttt caaccgcata cctttacaag aaccattgcc
    28621 ttgttggacg actttgccca tgctttaaac caagcagatg ctgtttatct agcgcaaatt
    28681 tatggctcgg ctcgtgaagt agatcatggt gacgttaagg tagaagacct agccaacaaa
    28741 atcaacaaaa aacaccaagt gattactgtt gaaaatgttt ctccactcct agaccatgac
    28801 aatgctgttt acgtctttat gggagcagga gacatccaaa cctatgaata ctcatttgag
    28861 cgtctcttgt ctaacttgac aagcaatgtt caataggatg ttcccatgga aattccaatt
    28921 aagatcattc aggcaagcaa gtctgatttg cctgagatag gggcacttca gacctcgtct
    28981 tttccagctg aaaagcagca actttcccat attttagaag aaagtatccg taagtgtgcg
    29041 gatacctttc ttctagctag ggatgaaaat caacttttag gctatatttt atcaagtccc
    29101 cagtcagaca atccgcaatg tctaaaagta cattctttag tcatcgagtc tgaccatcag
    29161 agacagggcc tgggaacact tcttcttgca gccttgaaag aggtggcagt tgagctggat
    29221 tacaaaggga ttcgtttgga gagtcctgat gagctgcttt cctattttga aatgaacggt
    29281 tttgttgatg aagaagcaac tttgctctat gcaactagcc agggctatag tatgatttgg
    29341 tttaatccct tttatctgga ggaacaatga aaatcagaca agcaagatta gaagatttgg
    29401 atcggattgt tgaacttgaa tttgaaaatt tttcggtcga agaagccatt cctccttctg
    29461 tctttgaagc acatttgaga gaaattcaga cctcttttct ggttgctgaa aaagaaggaa
    29521 gaatcatggg ttatatcgaa ggaccagttg gcctgcaccg ccatctgcaa gaccagtctt
    29581 ttacagaaga aataaaagac tatagtcatg agcctggtgg ttatatctct gtgacctgtc
    29641 tgtctattgc caaggaggca cagggactcg gactgggtca gaaattgctg acagccttga
    29701 aagaagttgc tcttgaagat gagagagatg gcattaatct aacctgtcat gactatctca
    29761 tcgcctacta tgaaaaacat ggatttgtca acgaaggcca gtcccagtca acctttgcag
    29821 gggaaacatg gtatgatatg gtctgggaaa tgaaaaaata agttaggaaa agtatcatag
    29881 attgcttttt ttggactttt aagatataat attatggatt atcaacaagg aggaaaaact
    29941 tttgagtgaa aagtcaagag aagaagagaa attaagcttt aaagagcaga ttctgagaga
    30001 tttagaaaaa gtaaaaggct atgatgaagt tctgaaagaa gatgaggcag tagttcgcac
    30061 tcctgcaaat gaaccttcaa ctgaagaact catggctgat tccttgtcaa cggtagagga
    30121 gattatgaga aaagctccta ccgtgcctac tcacccaagt caaggtgtac cagcttctcc
    30181 agcagatgag attcaaagag aaactcctgg tgttccaagt catccaagtc aagatgtacc
    30241 ttcttctcca gcggaagaaa gtggatcaag accaggtcca ggtcctgtta gacctaagaa
    30301 acttgaaaga gaatacaatg aaaccccaac aagggtagct gtttcctata cgacggcaga
    30361 gaaaaaagca gaacaagcag gtccagaaac acctacgcct gctacagaaa cagtggatat
    30421 catcagagat acatcacgtc gtagccgtag agaaggagca aaacccgtta agcctaagaa
    30481 agagaagaag tcacatgtga aagcttttgt gatttcattc cttgtattcc ttgccttgct
    30541 ctcagcaggt ggttactttg gttaccagta cgtgctagat tccttattac ctatcgatgc
    30601 taattctaag aaatatgtga cggttggaat tccagaaggt tcaaacgttc aagaaatcgg
    30661 tacgacgctt gaaaaagctg gtttggtaaa gcatggtctg atttttagtt tttatgccaa
    30721 gtataaaaat tataccgact tgaaagcagg ttactacaat ttgcaaaaga gtatgagtac
    30781 agaagactta ctcaaagagt tgcaaaaagg tggaacagat gaaccgcaag aacctgtact
    30841 tgcgactttg acaattccag aaggttatac cttggatcag attgctcaag ctgtgggtca
    30901 attgcaaggt gacttcaaag agtctttgac agcggaggct ttcttggcta aagttcaaga
    30961 tgagacgttt atcagtcaag cagtagcgaa atatcctact ttactggaaa gtttgcctgt
    31021 aaaagacagc ggtgcgcgtt atcgtttgga aggatacctt ttcccagcta catactctat
    31081 caaggaaagc acaactattg agagcttgat tgatgagatg ttagctgcta tggataagaa
    31141 cctatctcct tactatagta ctatcaaatc taaaaacttg actgtcaatg agttgttgac
    31201 cattgcttcc ttggtcgaaa aagaaggtgc caagacagaa gatcgtaagc tcattgcagg
    31261 tgtattctac aatcgtttga atcgtgatat gccacttcaa agtaatattg caatcttgta
    31321 tgcccaagga aaactggggc aaaatatcag tctagctgag gatgttgcga ttgataccaa
    31381 cattgattca ccttataatg tttataaaaa tgtaggtctc atgcctggtc cagtcgatag
    31441 tccaagtctg gatgcgattg agtcaagcat caatcaaact aagagcgata acctctactt
    31501 tgtagcagat gtcacagaag gcaaggtcta ctatgctaac aatcaagaag accacgaccg
    31561 caatgtcgct gaacatgtca acagcaaatt aaactaaaca aactaaaatt atgtgatact
    31621 tcacataatt ttctttagaa aatattatca gaagaaagtt gagaaaaatg gcagaaaaaa
    31681 catatcctat gacccttgag gaaaaggaaa aacttgaaaa agaattagaa gaattgaaat
    31741 tggttcgtcg accagaagtg gtagaacgca ttaagattgc ccgttcatac ggtgaccttt
    31801 cagaaaacag tgagtacgaa gcagctaagg atgaacaagc ctttgtcgaa ggacaaatct
    31861 ctagcttaga aacaaaaatc cgctatgctg aaatcgtcaa tagcgacgca gttgcccagg
    31921 acgaagtagc gattggtaaa acagtcacca tccaagaaat tggtgaggac gaagaagaag
    31981 tttatattat cgtaggttca gctggtgcag atgcctttgt aggtaaggtt tcaaatgaaa
    32041 gcccaattgg gcaggccttg attggcaaga aaacaggtga tacagcaacc attgaaacgc
    32101 ctgttggtag ctatgatgta aaaatcttga aggttgaaaa aacagcctaa aaacagaaaa
    32161 aggagtgggg aggcgatgtg cttcactcac tcctttttcc attttgctac tcttcgaaaa
    32221 tctcttcaaa ccacgtcagc gtcgccttgc cgtatgtatg gttactgact ttgtcagttt
    32281 catctacaac ctcaaaacag tgttttgagc taacttcgtc agtttcatct acaacctcaa
    32341 aactatgttt tgagctgact tcgtcagttt catctacaac ctcaaaacca tgttttgagc
    32401 cgacttcgtc agtttcatct acaacctcaa aactatgttt tgagctgact tcgtcagttc
    32461 tatctacaac ctcaaaatag tgttttgagc aacctgcggc tagtttccta gtttgctctt
    32521 tgatttttat tgagtattag atgtatagtg cattgaagtt aaaatagtac actttgattt
    32581 ctaagacatt gttagaaatt agattaaatt ccttaatcga tttgcgcatg ttttatttca
    32641 tttcactata ctttagattg gaaaataagg aatcacataa atcgcaagaa atagggaatc
    32701 tgattcgtgt ttataaccgt tcaaaaagag aagaggctga aagtgagcca cttaatcttt
    32761 atgtcgaaga tgaaaagggc aatctcctgg caggtttgat agcagagact tttggaaatt
    32821 ggctagaaat cgagtatttg tttgtaaaag aggaactgcg agggcaagga atcggttcaa
    32881 aactattgca acaggcagaa agtgaagcta agaatcgaaa ttgttgtttt gcctttgtca
    32941 atacttacca gttccaggca ccggactttt atcagaaaca tggctacaag gaagtttttt
    33001 ctttgcaaga ctgtctctac attaggcaaa gatattatta ccaaaagaat ctgtaaggtg
    33061 agtatggagg tataatacaa agagaggctc gcacataagt atggaggtgg actgatgtat
    33121 atgagtaact atcgataaat accagttata acctagaaat tgtgtctttc tagacgatat
    33181 tgaggacaat ataatcgtag ccccaaaatt aggaatcaag acttatcagg ttaagaaaag
    33241 aagtgatgtt gttgatattt taaacaattt atttaaacta aaaactctct atctattaat
    33301 ccgagattcc cctctcggat tttgtgttgc tttcattaaa tttacaggta agacttgcta
    33361 gcttcagtaa atatacacaa gtttttcaga atagagtgaa atccaaaaga aaatggaaat
    33421 aatgaaagct cttgtaggca taagaaagca cctctgtgtt atacttgttg ttcaaccaca
    33481 aacacaagaa aggcacagag atgcaagaca attatactac aaaagccaaa catttgacaa
    33541 tcgatagccg tcgcttaatc gaaagatgga aaaaagaagg aaaatcaaat agagaaattg
    33601 cctctctact tggaaaagct cctcaaacta tcacactgaa atcaagcgtg ggacagtccg
    33661 acaatgtctt ggaaaagggc gcttcaaaga ggtttattct gccgactacg ctcaacagtc
    33721 ttatgaaaac aatcgcaagc gctcggtcaa gaaatcaagc ttgaccaagg aactaaagga
    33781 aaagattctc cactatcata accaaaaatt ttcgcctgaa atgatggtta tggctaaagg
    33841 ggttaacgtg ggaatttcaa ccatttacta ttggattcat catggaaaat tggggttaag
    33901 caagcaggat ttgctttacc ctagaaaagg aaaagcgctt aagaaacagg ctagcaccaa
    33961 ctttaaacct gctggtcaat ccatcgaaca gcggcctgaa gctatcaatc ttcgcttgga
    34021 gaatgggcat tatgagattg atacggttct acttacgaga tcgaaaaact actgcttgct
    34081 tgtcttgacg gatcgaaaga gtagacatca gatcatccga ttgattccaa ataaaagtgc
    34141 tgaggtggtc aatcaggctc taaaactcat cttaaaacaa cacaagattc tttccatcac
    34201 ggcagataat ggaacggaat tcaatcgctt gtttgatata ttttctgagg agcacatcta
    34261 ttatgcgcac ccctatgcct cttgggaaag gggaactaat gagaatcaca acaggctcat
    34321 tcgtagatag ttacctaagg gaaccaagaa aatgactccc aaagaagtcg cattcatcga
    34381 aaagtggatt aacaactatc ctaaaaaatg cttggactac aagtcaccca gagaagactt
    34441 ctggatggct aacttgaact tgaaatttag caaaatggaa ataattttta ttaaacgctt
    34501 ccaatagcgg ttaaaagttg acaaatttaa attttaggac tacactaagt aagtaaattt
    34561 tattttaaag gagaatttgt tatgaattta acatttttag gcttatgtat tgcctgtatg
    34621 ggcgtatctg tcggtgaagg tttattgatg aatggactgt ttaaatcagt agcacgccaa
    34681 ccagatatgc tttctgagtt tcgtagtttg atgtttttag gtgttgcctt tattgaagga
    34741 actttctttg taactcttgt cttctcattt attatcaaat aaatacatgg aacgagaaga
    34801 aaagggagga ttttagatgg aagaaagtat taatccaatc atctctattg gtcctgttat
    34861 cttcaatctg actatgttag ccatgacttt gttgattgtg ggagttattt ttgtctttat
    34921 ttattgggca agccgcaata tgaccttgaa acccaaagga aagcaaaatg tacttgagta
    34981 tgtctatgac tttgttattg gatttacaga acctaacatt ggttcgcgct acatgaaaga
    35041 ttactcactc tttttccttt gtttattcct tttcatggtg attgccaata accttggctt
    35101 aatgacaaag cttcaaacga tcgatgggac taactggtgg agttcgccaa ccgctaattt
    35161 acagtatgac ttaaccttat cttttcttgt cattttgttg acacatatag aaagcgttcg
    35221 tcgtcgtgga tttaaaaaaa gtataaaatc ttttatgagt cctgtttttg tcataccgat
    35281 gaatatcttg gaagaattta caaacttctt atctttggct ttgcggattt ttgggaatat
    35341 ctttgcagga gaggtcatga cgagtttgtt acttcttctt tcccaccaag ctatttattg
    35401 gtatccagta gcctttggag ctaatttggc ttggactgca ttttctgtct ttatttcctg
    35461 catccaagct tatgttttta ctcttttgac atctgtgtat ttagggaata agattaatat
    35521 tgaagaggaa tagaaaggag taactgatgc acgtaacagt aggtgaatta attggtaatt
    35581 ttattttaat cactggctct tttattcttt tgctagtctt gattaaaaaa tttgcatggt
    35641 ctaatattac aggcattttc gaagaaagag ctgaaaaaat tgcttcagat attgacagag
    35701 ctgaagaagc ccgtcaaaaa gcagaagtat tggctcaaaa acgcgaagat gaattggctg
    35761 gtagccgtaa agaagctaag acaatcattg aaaatgcaaa ggaaacagct gagcaaagta
    35821 aggctaatat cttagcagat gctaaactag aagcaggaca cttaaaagaa aaagccaatc
    35881 aagaaattgc tcaaaataaa gtagaagctt tacagagtgt taagggtgag gtcgcagatt
    35941 tgaccatcag cttagctggt aaaatcatct cacaaaacct tgacagtcat gcccataaag
    36001 cactcattga tcagtatatc gatcagctag gagaagctta atggacaaga aaacagtaaa
    36061 ggtaattgaa aaatacagca tgccttttgt ccaattggta cttgaaaaag gagaagaaga
    36121 ccgtatcttt tcagacttga ctcaaatcaa gcaagttgtt gaaaaaacag gtctgccttc
    36181 ttttttaaaa caagtggcag tagacgagtc ggataaggaa aaaacaattg cttttttcca
    36241 agattctgtg tcgcctttat tacaaaactt tatccaggtt ctggcctaca atcacagagc
    36301 aaatcttttt tatgatgtgc ttgtagattg cttgaaccga cttgaaaaag aaacaaatcg
    36361 atttgaagtg acgattacgt ctgctcatcc tctaactgat gaacagaaga ctcgtttgct
    36421 ccctttgatt gagaaaaaaa tgtctctgaa agtaaggagt gtaaaagaac aaatcgatga
    36481 aagtctcatt ggtggttttg tcatttttgc caatcacaag acaattgatg tgagtattaa
    36541 acaacaactt aaagttgtta aagaaaattt gaaatagaaa gtggtgttct tttggcaatt
    36601 aacgcacaag aaatcagcgc tttaattaag caacaaattg aaaatttcaa acccaatttt
    36661 gatgtgactg aaacaggtgt tgtaacctat atcggggacg gtatcgcgcg tgctcacggc
    36721 cttgaaaatg tcatgagtgg agagttgttg aattttgaaa acggctctta tggtatggct
    36781 caaaacttgg agtcaacaga cgttggtatt atcatcctag gtgactttac agatatccgt
    36841 gaaggcgata caatccgccg tacagggaaa atcatggaag tccctgtagg tgaaagtctg
    36901 attggtcgtg ttgtggatcc gcttggtcgt ccagttgacg gtcttggaga aatccacact
    36961 gataaaactc gtccagtaga agcaccagct cctggtgtta tgcaacgtaa gtctgtttca
    37021 gaaccattgc aaactggttt gaaagctatt gacgcccttg taccgattgg tcgtggtcaa
    37081 cgtgagttga ttatcggtga ccgtcagaca gggaaaacaa ccattgcgat tgatacaatc
    37141 ttgaaccaaa aagatcaaga tatgatctgt atctacgtcg cgattggaca aaaagaatca
    37201 acagttcgta cgcaagtaga aacacttcgt cagtacggtg ccttggacta cacaatcgtt
    37261 gtgacagcct ctgcttcaca accatctcca ttgctcttcc tagctcctta tgctggggtt
    37321 gctatggcgg aagaatttat gtatcaaggt aagcatgttt tgattgtata cgatgatcta
    37381 tcaaaacaag cggtagctta tcgtgaactg tcgctcttgc ttcgtcgtcc tccaggtcgt
    37441 gaagccttcc caggggatgt tttctatctc cacagccgtt tgcttgagcg ctcagctaaa
    37501 gtttctgatg aacttggtgg tggatcaatt acagccctac catttatcga gacacaagca
    37561 ggagatatct cagcctatat cgcaaccaac gtgatttcta tcactgatgg acaaatcttc
    37621 cttggcgatg gcctcttcaa tgcaggtatt cgtccagcca tcgatgcggg ttcatctgta
    37681 tctcgtgtag gtggttctgc acaaatcaaa gccatgaaga aggttgctgg tacacttcgt
    37741 atcgaccttg cttcataccg tgagttggaa gcctttacta agtttggttc tgacttggac
    37801 gcagcaacac aggctaagtt gaaccgtgga cgtcgtaccg ttgaggtctt gaaacaacct
    37861 gttcacaaac cattacctgt tgagaaacaa gtaaccattc tttatgcttt gacacatggt
    37921 ttcttggata ctgttccagt agatgatatt gttcgtttcg aggaagagtt ccatgccttc
    37981 tttgatgctc aacatccaga gattttggaa accattcgtg atacaaaaga cttgccagaa
    38041 gaagcagtct tggatgctgc gattacagag tttctcaatc aatctagctt ccaataagaa
    38101 tagaggtgtc agatggcagt atctctaaat gatattaaaa caaaaatcgc ctcaacaaaa
    38161 aatacgagtc aaatcactaa tgccatgcaa atggtatcgg ctgctaagct aggtcgttct
    38221 gaagaagctg ctcgcaactt ccaagtttac gctcagaaag tgcgtaaact tttgacagat
    38281 atccttcatg gtaatggagc tggtgcttca actaatccga tgttgattag ccgttctgtg
    38341 aagaagacag gctatatcgt tatcacttca gaccgcggtt tggttggagg ttataattcc
    38401 tctattttga aagctgttat ggagttgaaa gaagaatacc acccagacgg taaaggtttt
    38461 gaaatgatct gtatcggtgg gatgggagct gatttcttta aggctcgcgg tattcaacca
    38521 ctttatgaat tacgtggctt gtcagaccaa cctagctttg atcaagttcg taagattatt
    38581 tcaaaaactg ttgaaatgta ccaaaatgaa ctctttgatg agctttatgt ttgctacaac
    38641 caccatgtca atacgctaac cagtcaaatg cgtgtggaac aaatgcttcc gattgttgac
    38701 ttggatccaa atgaagcgga tgaagagtac agcttgactt ttgaattgga aaccagccga
    38761 gaagaaattc tggagcagtt gttgcctcag tttgcagaaa gtatgattta cggtgccatt
    38821 atcgatgcca agacagctga gaatgctgcg ggcatgacag ccatgcaaac agcgacagat
    38881 aatgctaaga aagtcatcaa tgatttgaca attcagtata accgtgccag acaggcggcg
    38941 attacacaag aaattacaga aatcgtagca ggtgctagtg ccttagaata ggctctagtc
    39001 cagctcgtat gaaaatgaac ttaggaccta gttgagctag gaaccgacag tatcttatat
    39061 agaataggag aaggagatga gttcaggtaa aattgctcag gttatcggtc ccgttgtaga
    39121 cgttttgttt gcagcagggg aaaaacttcc tgagattaac aatgcacttg tcgtctacaa
    39181 aaatgacgaa agaaaaacaa aaatcgtcct tgaagtagcc ttggagttag gagatggtat
    39241 ggttcgtact atcgccatgg aatcaacaga tgggttgact cgtggaatgg aagtattgga
    39301 cacaggtcgt ccaatctctg taccagtagg taaagaaact ttgggacgtg tcttcaacgt
    39361 tttgggagat accattgact tggaagctcc ttttacagaa gacgcagagc gtcagccaat
    39421 tcataaaaaa gctccaactt ttgatgagtt gtctacctct tctgaaatcc ttgaaacagg
    39481 gatcaaggtt attgaccttc ttgcccctta ccttaaaggt ggtaaagttg gacttttcgg
    39541 tggtgccgga gttggtaaaa ctgtcttaat ccaagaattg attcacaaca ttgcccaaga
    39601 gcacggtggt atttcagtat ttgctggtgt tggggaacgt actcgtgagg ggaatgacct
    39661 ttactgggaa atgaaagaat caggcgttat cgagaaaaca gccatggtct ttggtcagat
    39721 gaatgagcca ccaggagcac gtatgcgtgt tgcccttact ggtttgacaa tcgctgaata
    39781 cttccgtgat gtggaaggcc aagacgtgct tctctttatc gataatatct tccgtttcac
    39841 tcaggctggt tcagaagtat ctgccctttt gggtcgtatg ccatcagccg ttggttacca
    39901 accaacactt gctacggaaa tgggtcaatt gcaagaacgt atcacatcaa ccaagaaggg
    39961 ttctgtaacc tctatccagg ctatctatgt gccagcggat gactatactg acccagcgcc
    40021 agcaacagcc ttcgctcact tggattcaac aacaaacttg gaacgtaagt tggtacaatt
    40081 gggtatctac ccagccgttg acccacttgc ttcaagctca cgtgccttgg cacctgaaat
    40141 cgttggagaa gagcactatg cagttgctgc tgaagtaaaa cgtgtccttc aacgttacca
    40201 tgaattgcaa gatatcattg ctatccttgg tatggatgag ctttctgatg aagaaaagac
    40261 cttggttgct cgcgcccgtc gtatccagtt cttcttgtca caaaacttca acgttgcgga
    40321 acaatttact ggtcagccag gttcttatgt tccagttgct gaaactgtac gtggctttaa
    40381 ggaaatcctt gatggtaaat acgaccactt gccagaagat gccttccgtg gtgtaggttc
    40441 tatcgaagat gtgattgcaa aagctgaaaa aatgggattt taagaggtga tctatggctc
    40501 agttaactgt ccagatcgtg acaccagatg gtctcgtcta tgatcaccat gccagctatg
    40561 tatcggttcg aactctggat ggtgagatgg ggatcttgcc acgacatgaa aatatgattg
    40621 cggttttagc agttgatgaa gtaaaggtaa aacgtatcga tgataaagat cacgtgaact
    40681 ggattgcagt aaacggtggc gttattgaaa ttgccaatga tatgatcaca atcgtcgctg
    40741 actctgcaga acgtgctcgt gatatcgata tcagtcgtgc agaacgtgcc aaacttcgtg
    40801 cagaacgtgc aattgaagaa gcacaagaca aacatttgat tgaccaagaa cgtcgtgcta
    40861 agattgcttt gcaacgtgct attaaccgta ttaatgtcgg aaatagacta taagaaaaaa
    40921 tgaacttgaa aataccaagt tcatttttta tggtgtttta aggagcaaaa cggatgcaga
    40981 ctgcttcggg aacatggaag tcgttggaga gttctgctag acgaccattg tcacaattac
    41041 gtttaaagac agttgcattg tcagagtctt gatggacaac aatgagaaat ttttggtcgg
    41101 gtgtcaaatc aaaatcacgt ggagtctgac catgcgttgg aacgatttct aataactcta
    41161 agctaccgtc cgcaaggatg gtatatactg cgatagaatc atggccacgg ttagaagcgt
    41221 agaggtattt accgtcttta gagagatgaa tagcagcggt tccattaaag ccttcgtaag
    41281 cttccggtaa agttgaaatg acctgcatac gttcaaattc gccaacgcca tcgtagatta
    41341 aaacttcgat agtactattg agttcacaaa tgagataagc gattttatag tggttatgga
    41401 aaatgatatg gcgtgagcct gctcctggct tgctgtgata ggtatagagc ttagataatt
    41461 ttccttcttg atcgaggtca taggtgatga cttggtcagt tcccaagtcg caggtcacta
    41521 gatagtggtc aggtgttaaa tctgtatagt gaacatgggg ggaagcttga ttttcatgtg
    41581 gaccttggcc actgtgttga tccatatcac taagtagaag actaccatct tcctggcgtt
    41641 tataaacaag gacttgtccc ttgtgatagt tagctgcgta aaccaaatca cgcttttcat
    41701 cgacagcaac ataacagtgg ggagctcctt cttcaacaac atgatttaac acagtcccgt
    41761 cagtttgata ggctgcaatt ccccccttat cgtcttggct accaacagtg tataaatgtt
    41821 ggtgctggtc aaaggcaagg taggttggac ttggctcagc tgcaaaaagt tctagatttg
    41881 aaagctgacc agtttctgta tcaaagtctg ccttgtaaat cccttgagaa gtacgacgtg
    41941 tataagttcc aaaataaaca gtttctttca ttactatacc tctgtgtaaa gataagacta
    42001 ttatatcaca aaaacaagta aattaaagat atccaattag atgtaagcac tttaaaaaag
    42061 agttattttg tttcaaaaat ggtataatga gagaacaata gaaaggaagt atttatggag
    42121 caaaaagaga aacattttag cctatcttgg tttttcaagt ggtttttaga taacaaggca
    42181 attacggtat ttttagtaac cttattattg ggactgaatc tttttatttt aagtaagatt
    42241 agttttctat tttcacctgt tttagacttt ttagcagttg tgatgttgcc agtcattttg
    42301 tctggtttgt tatattattt gttgaatcct attgttgatt ggatggagaa gcataaggtt
    42361 aatcgtgtta tagctatcac tattgtcttt gttatcatcg ctctctttat catttggggc
    42421 ttggcagtcg ccattccaaa tctgcaacgt caggttttga cctttgcaag aaacgttcct
    42481 gtttacttag aagatataga taggattgtt aatggattgg tagcccagca cctgccagat
    42541 gatttcagac ctcaattaga gcaagttttg accaattttt ctagccaggc tacagttttg
    42601 gcaagtaagg tttcatctca ggcagtcaac tgggtgagtg cctttattag cggggcttct
    42661 caagtgattg ttgccttgat tatcgttcct ttcatgctct tttatctctt gcgtgatggg
    42721 aaaggcttgc gtaactattt gacccaattc attccaagaa aattgaagga acctgttgga
    42781 caagttttat cagatgtgaa tcaacagttg tccaactatg ttcgagggca agtgacagtg
    42841 gctattattg tagcagtaat gtttatcatc ttcttcaaga ttattggtct acgctatgcg
    42901 gttacgctgg gggttactgc tggtatttta aatctggtcc cttatcttgg tagctttcta
    42961 gccatgcttc ctgctctagt attgggtttg attgctggtc cagtcatgct tttgaaagta
    43021 gtgattgtct ttatcgtaga acaaactatt gaaggccgtt ttgtctctcc attgattttg
    43081 ggaagtcaat taaacatcca ccctattaat gttctctttg ttttgttaac ttcaggatct
    43141 atgtttggta tctggggagt tttacttggt attccggttt atgcctctgc taaggttgtc
    43201 atttcagcca ttttcgaatg gtataaggta gtcagtggtc tatatgaatt agagggtgag
    43261 gaagtcaaga gtgaacaata gtcaacagat gttacaggct ttggaggagc aagatttaac
    43321 taaggctgag cattatttcg ccaaagcttt agaaaatgat tcaagtgatc ttctgtatga
    43381 attggcaact tatcttgaag ggattggttt ctatcctcag gccaaggaaa tttacctgaa
    43441 aattgtagag gattttccag aggttcatct taatctagct gcaattgcta gcgaggatgg
    43501 tcaaatagaa gaagccttta cctatcttga ggaaatccaa gctgacagtg actggtatgt
    43561 ctcgtctttg gctctgaagg cagaccttta ccagctggaa ggtttgacag atgtggcacg
    43621 tgagaaatta ttggaggcct tgacctactc agaggattct ctcttgatat tgggtttggc
    43681 agagttggat agtgagttgg aaaattacca agcggctatt caagcctatg cccagttaga
    43741 taatcgctcg atttatgagc aaacgggcat ttccacctat caacgaattg gctttgccta
    43801 tgctcagtta gggaaatttg aaacggctac tgagttttta gaaaaagccc tggagttaga
    43861 atacgatgac ttaacagctt ttgagttggc cagtctttat tttgatcaag aagaatatca
    43921 aaaagccacc ctctacttta agcagcttga taccatttct cctgactttg aaggctatga
    43981 gtatgggtac agtcaggctt tacataagga acatcaagtt caagaagccc tgcgtatcgc
    44041 taagcaagga ttagagaaaa atccctttga aactcgcctc ttgctagctg cttcacaatt
    44101 ttcttatgaa ttgcatgatg ctagtggtgc agaaaattat ctccttactg caaaagaaga
    44161 cgctgaggat acagaagaaa tcttgcttcg tttagccact atttatctgg agcaggagcg
    44221 ttatgaggat attctagaat tgcagagtga ggagccagaa aatcttttga ccaagtggat
    44281 gattgctcgt tcttatcaag aaatggacga tttggatact gcttatgagt attatcaaga
    44341 gttgacagga gatttgaagg acaatccaga atttctggaa cactatatct atctcttgcg
    44401 tgaattggga cattttgaag aagcaaaagt ccatgctcac acttacttaa aactggttcc
    44461 agatgatgtg caaatgcaag aactgtttga gagattgtaa gaatgtt
//
LOCUS       DBEJAU010000010        44295 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC323 isolate 683620
            SAMN38261939-rid24807223.denovo.010, whole genome shotgun sequence.
ACCESSION   DBEJAU010000010 DBEJAU010000000
VERSION     DBEJAU010000010.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261939
            Sequence Read Archive: SRR26833919
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 44295)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 44295)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576303.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576303.1
            Genome Coverage       :: 154x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/19/2025 01:05:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,121
            CDSs (total)                      :: 2,078
            Genes (coding)                    :: 1,943
            CDSs (with protein)               :: 1,943
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 36
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 72 of 135
            Pseudo Genes (incomplete)         :: 63 of 135
            Pseudo Genes (internal stop)      :: 51 of 135
            Pseudo Genes (multiple problems)  :: 46 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..44295
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261939-rid24807223.denovo.010"
                     /strain="GPSC323"
                     /isolate="683620"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            84..1666
                     /locus_tag="ACL29Z_000614"
                     /pseudo
     CDS             84..1666
                     /locus_tag="ACL29Z_000614"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007518194.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="YhgE/Pip family protein"
     gene            complement(1696..4248)
                     /locus_tag="ACL29Z_000615"
     CDS             complement(1696..4248)
                     /locus_tag="ACL29Z_000615"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfhO family protein"
                     /protein_id="HGR0068965.1"
                     /translation="MKSFLKTYRTYFISFIIPVVIMSGVYLSQGIYWNSDNSPLLGDG
                     FHQYVIFDVALRNILHGNSSLFYTFTSGLGLNFYALSSYYLGSFLAPLVYFFDLTNMP
                     DAVYLTTLLKFGLIGLSTFFSLNKLFQSIPQTLKLALSTSYALMSFTVSQLEIKTWLD
                     VFILIPLIITGLHLLITEKKLLLYFTSLSILFIQNYYFGYMTVLFLIFWYLCQISWDF
                     KTRKSSVLDFIVISFLAGMASLIMTLPTLFDLQTHGEKLTEVTKFQTESSWYLDLFAK
                     QFIGSFDTTKYGAIPMIFVGLFPFILTILFFTLKSIKFHVKLIYVIFFAFLIASFYIE
                     ALDLFWQGMHTPNMFLHRYAWIFSTLLIYTAAEVLKRLKELKVWNFLVSLFLVVAGFL
                     ATIYLKSHYSFLTDLNILLTLEFLVVYSLLLLAVIKKFISVNLFAILISLFILVEMSL
                     NASSQMDGIAKEWGFASRSAYSRDIPAMESFSTYIGNQFTRTEKLQTQTGNDSMKFNY
                     NGISQFSSVRNRSSSSTLDKLGFKSSGTNLNLRYANNSILADSLFGIQYNISDSPIDK
                     YGFKDIYQKDNLTLYENQYSLPIAVASQSVYNDVKFNEHTLDNQASFLNQLANVNFDY
                     FSPIPYEKTEKIENTNDLISVTSSSNEDAAIQYQIEVPENSQVYLSFINLHFSNDKQK
                     KVDILVNGEKKTFTTDNVFSFFNLGYTKEKKTFNINVSFPGNSQVSFESPTFYRLDTK
                     TFTEAIQKIKKQPVTVSTSKNKVFATYDVQQDTSIFFTIPYDKGWSAYQDGKKIEIKQ
                     AQTGFMKVDIPKGKGTITLSFIPNGFITGAICSFTSLLLFGIYNHRRKSSKA"
     gene            complement(4310..5932)
                     /locus_tag="ACL29Z_000616"
     CDS             complement(4310..5932)
                     /locus_tag="ACL29Z_000616"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015511338.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HGR0068966.1"
                     /translation="MLTVSDVSLRFSDRKLFDDVNIKFTEGNTYGLIGANGAGKSTFL
                     KILAGDIEPTTGHISLGPDERLSVLRQNHFDYEDERAIDVVIMGNEKLYSIMKEKDAI
                     YMKEDFSDEDGVRAAELEGEFAELGGWEAESEASQLLQNLNIPEELHYQNMSELANGE
                     KVKVLLAKALFGKPDVLLLDEPTNGLDIQSITWLEDFLIDFDNTVIVVSHDRHFLNKV
                     CTHMADLDFGKIKLYVGNYDFWKESSELAAKLLADRNAKAEEKIKQLQEFVARFSANA
                     SKSRQATSRKKMLDKIELEEIVPSSRKYPFINFKAEREIGNDLLTVENLTVKIDGETI
                     LDNISFILRPDDKTALIGQNDIQTTALIRAIMGDIDYEGTVKWGVTTSQSYLPKDNSA
                     DFAGGESILDWLRQFASKEEDDNTFLRGFLGRMLFSGDEVNKPVNVLSGGEKVRVMLS
                     KLMLLKSNVLVLDDPTNHLDLESISSLNDGLKNFKESIIFASHDHEFIQTLANHIIVL
                     SKNGVIDRIDETYDEFLENAEVQAKVKELWKD"
     gene            6138..7163
                     /gene="trpS"
                     /locus_tag="ACL29Z_000617"
     CDS             6138..7163
                     /gene="trpS"
                     /locus_tag="ACL29Z_000617"
                     /EC_number="6.1.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000165445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004830 - tryptophan-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006436 - tryptophanyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan--tRNA ligase"
                     /protein_id="HGR0068967.1"
                     /translation="MTKPIILTGDRPTGKLHIGHYVGSLKNRVLLQEEDKYDMFVFLA
                     DQQALTDHAKDPQTIVESIGNVALDYLAVGLDPNKSTIFIQSQIPELAELSMYYMNLV
                     SLARLERNPTVKTEISQKGFGESIPTGFLVYPIAQAADITAFKANYVPVGTDQKPMIE
                     QTREIVRSFNNAYNCDVLVEPEGIYPENERAGRLPGLDGNAKMSKSLNNGIYLADDAD
                     TLRKKVMSMYTDPDHIRVEDPGKIEGNMVFHYLDVFGRPEDAQEIADMKERYQRGGLG
                     DVKTKRYLLEILERELGPIRERRIEFAKDMGEVYNMIQKGSERAREVAGQTLSEVKGA
                     MGLHYFN"
     gene            7315..8793
                     /gene="guaB"
                     /locus_tag="ACL29Z_000618"
     CDS             7315..8793
                     /gene="guaB"
                     /locus_tag="ACL29Z_000618"
                     /EC_number="1.1.1.205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000073411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003938 - IMP dehydrogenase activity
                     [Evidence IEA];
                     GO_process: GO:0006164 - purine nucleotide biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IMP dehydrogenase"
                     /protein_id="HGR0068968.1"
                     /translation="MSNWDTKFLKKGFTFDDVLLIPAESHVLPNDADLTTKLADNLTL
                     NIPIITAAMDTVTESQMAIAIARAGGLGVIHKNMSIAQQADEVRKVKRSENGVIIDPF
                     FLTPEHTIAEADELMGRYRISGVPVVETLENRKLVGILTNRDLRFISDYNQPISNHMT
                     SENLVTAPVGTDLATAESILQEHRIEKLPLVDEEGSLSGLITIKDIEKVIEFPNAAKD
                     EFGRLLVAGAVGVTSDTFERAEALFEAGADAIVIDTAHGHSAGVLRKIAEIRAHFPDR
                     TLIAGNIATAEGARALYEAGVDVVKVGIGPGSICTTRVIAGVGVPQVTAIYDAAAVAR
                     EYGKTIIADGGIKYSGDIVKALAAGGNAVMLGSMFAGTDEAPGETEIFQGRKFKTYRG
                     MGSIAAMKKGSSDRYFQGSVNEANKLVPEGIEGRVAYKGAAADIVFQMIGGIRSGMGY
                     CGAANLKELHDNAQFIEMSGAGLKESHPHDVQITNEAPNYSM"
     gene            complement(8844..9941)
                     /gene="recF"
                     /locus_tag="ACL29Z_000619"
     CDS             complement(8844..9941)
                     /gene="recF"
                     /locus_tag="ACL29Z_000619"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000266665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA replication/repair protein RecF"
                     /protein_id="HGR0068969.1"
                     /translation="MWLQHLSLKTFRNYKETKIDFNPKLNVFLGRNAQGKTNMLEAIY
                     FLALTRSHRTRTDKNLIHFDEEQLHLSGLVQKKTGSIPLEIELTQKGRVTKVNHLKQA
                     RLSDYVGHMNVVLFAPEDLQLIKGAPSIRRKFIDMELGQIKPIYLSDLTNYNHILKQR
                     NTYLKSDQKIDETFLSVLDDQLVDYGCRVMNHRLDFIKKLESFGRKKHFELSNQIEEL
                     SISYQSSVNITDKQNLSESFKIALEKSRSRDLFKKNTGVGPHRDDISFYINGMDASFG
                     SQGQHRSLVLSIKLAEIELMESITTESPILLLDDVMSELDNTRQLKLLETISQSIQTF
                     ITTTSLDHLQNLPENLSIFTIQDGKAAVNGN"
     gene            complement(9944..10312)
                     /gene="yaaA"
                     /locus_tag="ACL29Z_000620"
     CDS             complement(9944..10312)
                     /gene="yaaA"
                     /locus_tag="ACL29Z_000620"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000455867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="S4 domain-containing protein YaaA"
                     /protein_id="HGR0068970.1"
                     /translation="MEYKLFEEFITLQALLKELGITHSGGAIKSFLSEHSVYFNRELE
                     SRRGKKLRIGDKVDIPDMNIDILLTQPTSEEQDEYQADKVEKERIAKLVKKMNKGVKK
                     DKSKPASSPKSQQAPRFPGR"
     gene            10471..11721
                     /locus_tag="ACL29Z_000621"
     CDS             10471..11721
                     /locus_tag="ACL29Z_000621"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000424255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="M16 family metallopeptidase"
                     /protein_id="HGR0068971.1"
                     /translation="MELVHGISTHFIQSKKFKTNKITVRFTAPLSLDTIAGHMLSASM
                     LETANQMYPTSQDLRRHLASLYGTDMSTNCFRRGQSHIIELTFTYVRDEFLSRKNVLT
                     SQILELVKETLFSPVVVDNGFDPALFEIEKKQLLASLAADMDDSFYFAHKELDKLFFH
                     DERLQLEYSDLRNRILAETPQSSYSCFQEFLANDRIDFFFLGDFNEVEIQNVLESFGF
                     KGRKGDVKVQYCQPYSNILQEGMVRKNVGQSILELGYHYRSKYGDEQHLPMIVMNGLL
                     GGFAHSKLFTNVRENAGLAYTISSELDLFSGFLRMYAGINRENRNQARKMMNNQLLDL
                     KKGYFTEFELNQTKEMIRWSLLLSQDNQSSLIERAYQNALFGKSSADFKSWIVKLEQI
                     DKDAICRVANNVKLQAIYFMEGIE"
     gene            11718..13001
                     /locus_tag="ACL29Z_000622"
     CDS             11718..13001
                     /locus_tag="ACL29Z_000622"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="M16 family metallopeptidase"
                     /protein_id="HGR0068972.1"
                     /translation="MTKVVFEEKYYPAVKEKVYRTRLANGLTVALLPKKEFKEVYGSV
                     TVQFGSVDTFVTEVDGDVKQYPGGIAHFLEHKLFEREDSSDLMSAFTSLGADSNAFTS
                     FTKTNYLFSATDYFLENLDLLDELVTSAHFTEASILTEQDIIQQEREMYQDDPDSCLF
                     FSTLANLYPGTPLATDIVGSEESISQINLTNLQENFTKFYKPVNMSLFLVGNFDVERV
                     QDYFESKELKDSDFQEVAREKLFLQPVKPTDSMRMEVSSPKLAIGVRGKREVSEADCY
                     RHHILLKLLFAMMFGWTSDRFQKCYESGKIDASLSLEVEVTSRFHFVMLTMDTKEPVA
                     LSHQFRKSIRNFTKDLDITEEHLDIIKREMFGEFFSSMNSLEFIATQYDAFENGETIF
                     DLPKILQEITLEDVLDAGHHLIDDGDIVDFTIFPS"
     gene            13043..13864
                     /gene="rodZ"
                     /locus_tag="ACL29Z_000623"
     CDS             13043..13864
                     /gene="rodZ"
                     /locus_tag="ACL29Z_000623"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytoskeleton protein RodZ"
                     /protein_id="HGR0068973.1"
                     /translation="MRKKTIGEVLRLARINQGLSLDELQKKTEIQLDMLEAMEADDFD
                     QLPSPFYTRSFLKKYAWAVELDDQIVLDAYDSGSMITYEEVDVDEDELTGRRRSSKKK
                     KKKTSFLPLFYFILFALSILIFVTYYVWNYIQTQPEEPSLSNYSVVQSTSSTSSVPHS
                     SSSSSSSIESAISVSGEGNHVEIAYKTSKETVKLQLAVSDVTSWVSVSESELEGGVTL
                     SPKKKSAEATVATKSPVTITLGVVKGVDLTVDNQTVDLSKLTAQTGQITVTFTKN"
     gene            13875..14420
                     /gene="pgsA"
                     /locus_tag="ACL29Z_000624"
     CDS             13875..14420
                     /gene="pgsA"
                     /locus_tag="ACL29Z_000624"
                     /EC_number="2.7.8.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000712151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008444 -
                     CDP-diacylglycerol-glycerol-3-phosphate
                     3-phosphatidyltransferase activity [Evidence IEA];
                     GO_process: GO:0008654 - phospholipid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="CDP-diacylglycerol--glycerol-3-phosphate
                     3-phosphatidyltransferase"
                     /protein_id="HGR0068974.1"
                     /translation="MKKEQIPNLLTIGRILFIPIFIFILTIGNSIESHIVAAIIFAVA
                     SITDYLDGYLARKWNVVSNFGKFADPMADKLLVMSAFIMLIELGMAPAWIVAVIICRE
                     LAVTGLRLLLVETGGTILAAAMPGKIKTFSQMFAIIFLLLHWTLLGQVLLYVALFFTI
                     YSGYDYFKGSAYVFKGTFGSK"
     gene            14417..15244
                     /locus_tag="ACL29Z_000625"
     CDS             14417..15244
                     /locus_tag="ACL29Z_000625"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor ABC transporter
                     ATP-binding protein"
                     /protein_id="HGR0068975.1"
                     /translation="MKSIIDVKNLSFRYKENQNYYDVKDITFHVKRGEWLSIVGHNGS
                     GKSTTVRLIDGLLEAESGEIVIDGQRLTEENVWNIRRQIGMVFQNPDNQFVGATVEDD
                     VAFGLENQGLSRQEMKKRVEEALALVGMLDFKKREPARLSGGQKQRVAIAGVVALRPA
                     ILILDEATSMLDPEGRRELIGTVKGIRKDYDMTVISITHDLEEVAMSDRVLVMKKGEI
                     ESTSSPRELFSRNDLDQIGLDDPFANQLKKFLSQNGYNLPENYLTESELEDKLWELL"
     gene            15229..16068
                     /locus_tag="ACL29Z_000626"
     CDS             15229..16068
                     /locus_tag="ACL29Z_000626"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000510406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009898 - cytoplasmic side of plasma
                     membrane [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0006810 - transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter ATPase"
                     /protein_id="HGR0068976.1"
                     /translation="MGIALENVNFTYQEGTPLASAALSDVSLTIEDGSYTALIGHTGS
                     GKSTILQLLNGLLVPSQGSVRVFDTLITSTSKNKDIRQIRKQVGLVFQFAENQIFEET
                     VLKDVAFGPQNFGVSEEDAVKTAREKLALVGIDESLFDRSPFELSGGQMRRVAIAGIL
                     AMEPSILVLDEPTAGLDPLGRKELMTLFKKLHQSGMTIVLVTHLMDDVAEYANQVYVM
                     EKGRLVKGGKPSDVFQDVVFMEEVQLGVPKITAFCKRLADRGVSFKRLPIKIEEFKES
                     LNG"
     gene            16061..16855
                     /locus_tag="ACL29Z_000627"
     CDS             16061..16855
                     /locus_tag="ACL29Z_000627"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000377903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter transmembrane
                     protein EcfT"
                     /protein_id="HGR0068977.1"
                     /translation="MDSMILGRYIPGDSIVHRLDPRSKLLAMMLLILIVFWANNPLTN
                     LILFIATGIFIALSGVSLSFFIQGLKSMFFLIAFTTIFQLFFISNGNVLFEFSFVRIT
                     DYALQQAGIIFCRFVLIIFFSTLLTLTTMPLSLASAVEALLAPLKRVKVPVHEIGLML
                     SMSLRFVPTLMDDTTRIMNAQKARGVDFGEGSIVQKVKAMIPILIPLFATSLKRADSL
                     AIAMEARGYQGGKGRSQYRQLKWTLKDTLTILVILVLGCCLFFLKS"
     gene            16914..17732
                     /gene="mreC"
                     /locus_tag="ACL29Z_000628"
     CDS             16914..17732
                     /gene="mreC"
                     /locus_tag="ACL29Z_000628"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001078980.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0008360 - regulation of cell shape
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="rod shape-determining protein MreC"
                     /protein_id="HGR0068978.1"
                     /translation="MNRFKKSKYVIIVFVTVLLVSALLATTYSSTIVTKLGDGISLVD
                     RVVQKPFQWFDSVKSDLAHLTRTYNENESLKKQLYQLEVKSNEVESLKTENEQLRQLL
                     DMKSKLQATKTLAADVIMRSPVSWKQELTLDAGRSKGASENMLAIANGGLIGSVSKVE
                     ENSTIVNLLTNTENADKISVKIQHGSITIYGIIIGYDKENDVLKISQLNSNSDISAGD
                     KVTTGGLGNFNVADIPVGEVVATTHSTDYLTREVTVKLSADTHNVDVIELVGNS"
     gene            17732..18226
                     /gene="mreD"
                     /locus_tag="ACL29Z_000629"
     CDS             17732..18226
                     /gene="mreD"
                     /locus_tag="ACL29Z_000629"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001249461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0008360 - regulation of cell shape
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="rod shape-determining protein MreD"
                     /protein_id="HGR0068979.1"
                     /translation="MRQLKRVGVFLLLPFFVLIDAHISQLLGSFFPHVHLASHFLFLF
                     LLFETIEVSEYLYLVYCFVIGLVYDVYFFHLIGITTLLFILLGAFLHKLNSVILLNRW
                     TRMLAMIVLTFLFEMGSYLLAFMVGLTVDSMSIFIVYSLVPTMILNFLWITVFQFIFE
                     KYYL"
     gene            18320..19498
                     /gene="pcsB"
                     /locus_tag="ACL29Z_000630"
     CDS             18320..19498
                     /gene="pcsB"
                     /locus_tag="ACL29Z_000630"
                     /EC_number="3.2.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000727004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan hydrolase PcsB"
                     /protein_id="HGR0068980.1"
                     /translation="MKKKILASLLLSTVMVSQVAVLTTAHAETTDDKIAAQDNKISNL
                     TAQQQEAQKQVDQIQEQVSAIQAEQSNLQAENDRLQAESKKLEGEITELSKNIVSRNQ
                     SLEKQARSAQTNGAVTSYINTIVNSKSITEAISRVAAMSEIVSANNKMLEQQKADKKA
                     ISEKQVANNDAINTVIANQQKLADDAQALTTKQAELKAAELSLAAEKATAEGEKASLL
                     EQKAAAEAEARAAAVAEAAYKEKRASQQQSVLASANTNLTAQVQAVSESAAAPVRAKV
                     RPTYSTNASSYPIGECTWGVKTLAPWAGDYWGNGAQWATSAAAAGFRTGSTPQVGAIA
                     CWNDGGYGHVAVVTAVESTTRIQVSESNYAGNRTIGNHRGWFNPTTTSEGFVTYIYAD
                     "
     gene            19722..20501
                     /gene="rpsB"
                     /locus_tag="ACL29Z_000631"
     CDS             19722..20501
                     /gene="rpsB"
                     /locus_tag="ACL29Z_000631"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015935 - small ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S2"
                     /protein_id="HGR0068981.1"
                     /translation="MAVISMKQLLEAGVHFGHQTRRWNPKMAKYIFTERNGIHVIDLQ
                     QTVKYADQAYDFMRDAAANDAVVLFVGTKKQAADAVAEEAVRSGQYFINHRWLGGTLT
                     NWGTIQKRIARLKEIKRMEEDGTFEVLPKKEVALLNKQRARLEKFLGGIEDMPRIPDV
                     MYVVDPHKEQIAVKEAKKLGIPVVAMVDTNTDPDDIDVIIPANDDAIRAVKLITAKLA
                     DAIIEGRQGEDAVAVEAEFAASETQADSIEEIVEVVEGDNA"
     gene            20580..21620
                     /gene="tsf"
                     /locus_tag="ACL29Z_000632"
     CDS             20580..21620
                     /gene="tsf"
                     /locus_tag="ACL29Z_000632"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003053075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003746 - translation elongation factor
                     activity [Evidence IEA];
                     GO_process: GO:0006414 - translational elongation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="translation elongation factor Ts"
                     /protein_id="HGR0068982.1"
                     /translation="MAEITAKLVKELREKSGAGVMDAKKALVETDGDIEKAIELLREK
                     GMAKAAKKADRVAAEGLTGVYVNGNVAAVIEVNAETDFVAKNAQFVELVNTTAKVIAE
                     GKPANNEEALALIMPSGETLEAAYVSATATIGEKISFRRFALIEKTDAQHFGAYQHNG
                     GRIGVISVVEGGDEALAKQLSMHIAAMKPTVLSYKELDEQFVKDELAQLNHVIDQDNE
                     SRAMVNKPALPHLKYGSKAQLTDDVIAQAEADIKAELAAEGKPEKIWDKIIPGKMDRF
                     MLDNTKVDQAYTLLAQVYIMDDSKTVEAYLESVNASVVEFARFEVGEGIEKAANDFEA
                     EVAATMAAALNN"
     gene            21867..22217
                     /gene="tnpB"
                     /locus_tag="ACL29Z_000633"
     CDS             21867..22217
                     /gene="tnpB"
                     /locus_tag="ACL29Z_000633"
                     /inference="COORDINATES: protein motif:HMM:NF017528.4"
                     /note="TnpB, as the term is used for proteins encoded by
                     IS66 family insertion elements, is considered an accessory
                     protein, since TnpC, encoded by a neighboring gene, is a
                     DDE family transposase; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS66 family insertion sequence element accessory
                     protein TnpB"
                     /protein_id="HGR0068983.1"
                     /translation="MIIQLSDLGQVHLVCSKIDMRQGIDSLAYVVKTHFELDPFSGQV
                     FLFCGGRKDRFKALYWDGQGFWLLYKRFENVRLTWPSTEKDVKALTPEQVDWLMKGFS
                     ITPKINPSESRDFY"
     gene            complement(22240..22548)
                     /locus_tag="ACL29Z_000634"
                     /pseudo
     CDS             complement(22240..22548)
                     /locus_tag="ACL29Z_000634"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611577.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            22530..23059
                     /locus_tag="ACL29Z_000635"
                     /pseudo
     CDS             22530..23059
                     /locus_tag="ACL29Z_000635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_050084071.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(23134..24054)
                     /gene="cysK"
                     /locus_tag="ACL29Z_000636"
     CDS             complement(23134..24054)
                     /gene="cysK"
                     /locus_tag="ACL29Z_000636"
                     /EC_number="2.5.1.47"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000029859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004124 - cysteine synthase activity
                     [Evidence IEA];
                     GO_process: GO:0006535 - cysteine biosynthetic process
                     from serine [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine synthase A"
                     /protein_id="HGR0068984.1"
                     /translation="MSIYNNITELIGQTPIVKLNNIVPEGAADVYIKLEAFNPGSSVK
                     DRIALSMIEKAEQDGILKPGSTIVEATSGNTGIGLSWVGAAKGYKVVIVMPETMSVER
                     RKIIQAYGAELVLTPGSEGMKGAIAKAQEIAAERDGFLPLQFDNPANPEVHERTTGAE
                     ILAAFGKDGLDAFVAGVGTGGTISGVSHALKSENSNIQVFAVEADESAILSGEKPGPH
                     KIQGISAGFIPDTLDTKAYDGIVRVTSDDALALGREIGGKEGFLVGISSAAAIYGAIE
                     VAKKLGTGKKVLALAPDNGERYLSTALYEL"
     gene            complement(24339..24974)
                     /locus_tag="ACL29Z_000637"
     CDS             complement(24339..24974)
                     /locus_tag="ACL29Z_000637"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000395753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YigZ family protein"
                     /protein_id="HGR0068985.1"
                     /translation="MEFRTIKEDDQVQEEIKKSRFICHAKRVYSEEEARDFITAIKKE
                     HYKATHNCSAFIIGERSEIKRTSDDGEPSGTAGVPMLGVLENHNLTNVCVVVTRYFGG
                     IKLGAGGLIRAYAGSVALAVKEIGIIEIKEQAGIAIQMSYAQYQEYSNFLKEHDLMEL
                     DTNFTDQVDTMIYVDKEEKETIKAALVEFFNGKVTLTDQGLREVEVPVNLV"
     gene            25030..26328
                     /locus_tag="ACL29Z_000638"
     CDS             25030..26328
                     /locus_tag="ACL29Z_000638"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000867598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HGR0068986.1"
                     /translation="MKVNLDYLGRLFTENELTEEERQLAEKLPAMRKEKGKLFCQRCN
                     STILEEWYLPIGAYYCRECLLMKRVRSDQTLYYFPQEDFPKQDVLKWRGQLTPFQEKV
                     SEGLLQAVDKQKPTLVHAVTGAGKTEMIYQVVAKVINAGGAVCLASPRIDVCLELYKR
                     LQQDFSCGIALLHGESEPYFRTPLVVATTHQLLKFYQAFDLLIVDEVDAFPYVDNPML
                     YHAVKNSVKENGLRIFLTATSTNELDKKVRLGELKRLNLPRRFHGNPLIIPKPIWLSD
                     FNRYLDKNRLSPKLKSYIEKQRKTAYPLLIFASEIKKGEQLEEILQEQFPNEKIGFVS
                     SVTEDRLEQVQAFRDGELTILISTTILERGVTFPCVDVFVVEANHRLFTKSSLIQIGG
                     RVGRSMDRPTGDLLFFHDGLNASIKKAIKEIQMMNKEAGL"
     gene            26325..26987
                     /locus_tag="ACL29Z_000639"
     CDS             26325..26987
                     /locus_tag="ACL29Z_000639"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000649954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ComF family protein"
                     /protein_id="HGR0068987.1"
                     /translation="MKCLLCGQTMKTVLTFSSLLLLRNDDSCLCSDCDSTFERIGEEN
                     CPNCMKTELSTKCQDCQFWCKEGVGVSHRAIFTYNQAMKDFFSRYKFDGDFLLRKVFA
                     SFLSEELKKYKEYQFVVIPLSPDRYANRGFNQVEGLVEAAGFEYLDLLEKREERASSS
                     KNRSERLGTELPFFIKSGVTIPKKILLIDDIYTTGATINRVKKLLEEAGAKDVKTFSL
                     VR"
     gene            27067..27615
                     /gene="raiA"
                     /locus_tag="ACL29Z_000640"
     CDS             27067..27615
                     /gene="raiA"
                     /locus_tag="ACL29Z_000640"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000599099.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0045182 - translation regulator activity
                     [Evidence IEA];
                     GO_process: GO:0009386 - translational attenuation
                     [Evidence IEA];
                     GO_process: GO:0036211 - protein modification process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome-associated translation inhibitor RaiA"
                     /protein_id="HGR0068988.1"
                     /translation="MIKYSIRGENLEVTEAIRDYVVSKLEKIEKYFQPEQELDARINL
                     KVYREKTAKVEVTIPLGSITLRAEDVSQDMYGSIDLVTDKIERQIRKNKTKIERKNKN
                     KVATGQLFTDALVEDSNVVQSKVVRSKQIDLKPMDLEEAILQMDLLGHDFFIYVDVED
                     QTTNVIYRREDGEIGLLEVKES"
     gene            27751..29724
                     /locus_tag="ACL29Z_000641"
     CDS             27751..29724
                     /locus_tag="ACL29Z_000641"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255323.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DHH family phosphoesterase"
                     /protein_id="HGR0068989.1"
                     /translation="MKKFYVSPIFPILVGLIAFGVLSTFIIFVNNNLLTVLILFLFVG
                     GYVFLFKKLRVHYTRSDVEQIQYVNHQAEESLTSLLEQMPVGVMKLNLSSGEVEWFNP
                     YAELILTKEDGDFDLEAVQTIIKASVGNPSTYAKLGEKRYAVHMDASSGVLYFVDVSR
                     EQAITDELVTSRPVIGIVSVDNYDDLEDATSESDISQINSFVANFISEFSEKYMMFSR
                     RVSMDRFYLFTDYTVLEGLMNDKFSVIDAFREESKQRQLPLTLSMGFSYGDGNHDEIG
                     KVALLNLNLAEVRGGDQVVVKENDETKNPVYFGGGSAASIKRTRTRTRAMMTAISDKI
                     RSVDQVFVVGHKNLDMDALGSAVGMQLFASNVIENSYALYDEEQMSPDIERAVSFIEK
                     EGVTKLLSVKDAMGMVTNRSLLILVDHSKTALTLSKEFYDLFTQTIVIDHHRRDQDFP
                     DNAVITYIESGASSASELVTELIQFQNSKKNRLSRMQASVLMAGMMLDTKNFTSRVTS
                     RTFDVASYLRTRGSDSIAIQEIAATDFEEYREVNELILQGRKLGSDVLIAEAKDTKCY
                     DTVVISKAADAMLAMSGIEASFVLAKNTQGFISISARSRSKLNVQRIMEELGGGGHFN
                     LAAAQIKDVTLSEAGEKLTEIVLNEIKEKEKEE"
     gene            29721..30173
                     /gene="rplI"
                     /locus_tag="ACL29Z_000642"
     CDS             29721..30173
                     /gene="rplI"
                     /locus_tag="ACL29Z_000642"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011999581.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L9"
                     /protein_id="HGR0068990.1"
                     /translation="MKVIFLADVKGKGKKGEIKEVPTGYAQNFLIKKNLAKEATAQAV
                     GELRGKQKSEEKAHAEMIAEGKAIKAQLEAEETVVEFVEKVGPDGRTFGSITNKKIAE
                     ELQKQFGIKIDKRHIQVQAPIRAVGLIDVPVKIYQDITSVINLRVKEG"
     gene            30217..31569
                     /gene="dnaB"
                     /locus_tag="ACL29Z_000643"
     CDS             30217..31569
                     /gene="dnaB"
                     /locus_tag="ACL29Z_000643"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000852490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003678 - DNA helicase activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="replicative DNA helicase"
                     /protein_id="HGR0068991.1"
                     /translation="MAEVEELRVQPQDILAEQSVLGAIFIDESKLVFVREYIESRDFF
                     KYAHRLIFQAMVDLSDRGDAIDATTVRTILDNQGDLQNIGGLSYLVEIVNSVPTSANA
                     EYYAKIVAEKAMLRRLIAKLTESVNQAYEASQPADEIIAQAEKGLIDVSENANRSGFK
                     NIRDVLNLNFGNLEARSQQTTDITGIATGYRDLDHMTTGLHEEELIILAARPAVGKTA
                     FALNIAQNIGTKLDKTVAIFSLEMGAESLVDRMLAAEGLVESHSIRTGQLTDEEWQKY
                     TIAQGNLANASIYIDDTPGIRITEIRSRSRKLAQETGNLGLILIDYLQLITGTGRENR
                     QQEVSEISRQLKILAKELKVPVIALSQLSRGVEQRQDKRPVLSDIRESGSIEQDADIV
                     AFLYRDDYYERGGEEEEGIPNNKVEVIIEKNRSGARGTVELIFQKEYNKFSSISKREA
                     "
     gene            31571..31837
                     /locus_tag="ACL29Z_000644"
     CDS             31571..31837
                     /locus_tag="ACL29Z_000644"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001278167.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Veg family protein"
                     /protein_id="HGR0068992.1"
                     /translation="MSDAFTDVAKMKKIKEEIKAHEGQVVEMTLENGRKRQKNRLGKL
                     IEVYPSLFIVEFGDVEGDKQVNVYVESFTYSDILTEKNLIHYLD"
     gene            31926..33272
                     /gene="cbpD"
                     /locus_tag="ACL29Z_000645"
     CDS             31926..33272
                     /gene="cbpD"
                     /locus_tag="ACL29Z_000645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000698569.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline binding-anchored murein hydrolase CbpD"
                     /protein_id="HGR0068993.1"
                     /translation="MKILPFIARGTSYYLKMSVKKLVPFLVVGLMLAAGDSVYAYSRG
                     NGSIARGDDYPAYYKNGSQEIDQWRMYSRQCTSFVAFRLSNVNGFEMPAAYGNANEWG
                     HRARREGYRVDNTPTIGSITWSTAGTYGHVAWVSNVMGDQIEIEEYNYGYTESYNKRV
                     IKANTMTGFIHFKDLDGGSVGNSQSSASTGGTHYFKTKSAIKPEPLASGTVIDYYYPG
                     EKVHYDQIFEKDGYKWLSYTAYNGSYRYVQLEAVNKNPLGNSVLSSTGGTHYFKTKSA
                     IKTEPLVSATVIDYYYPGENVHYDQILEKDGYKWLSYTAYNGSRRYIQLEGVTSSQNY
                     QNQSGNISSYGSHSSSTVGWKKINGSWYHFKSNGSKSTGWLKDGSSWYYLKLSGEMQT
                     GWLKENGLWYYLGSSGAMKTGWYQVSGKWYYSYSSGALAVNTTVDGYRVNSDGERV"
     regulatory      33355..33457
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            33528..33818
                     /locus_tag="ACL29Z_000646"
     CDS             33528..33818
                     /locus_tag="ACL29Z_000646"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000647657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MTH1187 family thiamine-binding protein"
                     /protein_id="HGR0068994.1"
                     /translation="MKASIALQVLPLVQGIDRIAVIDQVIAYLQTQEVTMVVTPFETV
                     LEGEFDELMRILKEALEVAGQEADNVFANVKINVGEILSIDEKLEKYTETTH"
     gene            33781..34539
                     /locus_tag="ACL29Z_000647"
     CDS             33781..34539
                     /locus_tag="ACL29Z_000647"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009013602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HGR0068995.1"
                     /translation="MRNLRSILRRHISLLGFLGVLSIWQLAGFLKLLPKFILPTPLEI
                     LQPFVRDREFLWHHSWATLRVALLGLILGVLIACLMAVLMDSLTWLNDLIYPMMVVIQ
                     TIPTIAIAPILVLWLGYGILPKIVLIILTTTFPIIVSILDGFRHCDKDMLTLFSLMRA
                     KPWQILWHFKIPVSLPYFYAGLRVSVSYAFITTVVSEWLGGFEGLGVYMIQSKKLFQY
                     DTMFAIIILVSIISLLGMKLVDISEKYVIKWKRS"
     gene            34578..35585
                     /locus_tag="ACL29Z_000648"
     CDS             34578..35585
                     /locus_tag="ACL29Z_000648"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HGR0068996.1"
                     /translation="MKKTWKVFLTLVTALVAVVLVACGQGTASKDNKEAELKKVDFIL
                     DWTPNTNHTGLYVAKEKGYFKEAGVDVDLKLPPEESSSDLVINGKAPFAVYFQDYMAK
                     KLEKGAGITAVAAIVEHNTSGIISRKSDNVSSPKDLVGKKYGTWNDPTELAMLKTLVE
                     SQGGDFEKVEKVPNNDSNSITPIANGVFDTAWIYYGWDGILAKSQGVDANFMYLKDYV
                     KEFDYYSPVIIANNDYLKDNKEEARKVIQAIKKGYQYAMEHPEEAADILIKNAPELKE
                     KRDFVIESQKYLSKEYASDKEKWGQFDAARWNAFYKWDKENGILKEDLTDKGFTNEFV
                     K"
     gene            35585..36313
                     /locus_tag="ACL29Z_000649"
     CDS             35585..36313
                     /locus_tag="ACL29Z_000649"
                     /EC_number="7.6.2.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGR0068997.1"
                     /translation="MTEIRLEHVSYAYGQERILEDINLQVTSGEVVSILGPSGVGKTT
                     LFNLIAGILEVQSGRIVLDGEENPKGRVSYMLQKDLLLEHKTVLGNIILPLLIQKVDK
                     AEAISRADKILATFQLTAVRDKYPHELSGGMRQRVALLRTYLFGHKLFLLDEAFSALD
                     EMTKMELHAWYLEIHKQLQLTTLIITHSIEEALNLSDRIYILKNRPGQIVSEIKLDWS
                     EDEDKEVQKIAYKRQILAELGLDK"
     gene            36432..36890
                     /locus_tag="ACL29Z_000650"
     CDS             36432..36890
                     /locus_tag="ACL29Z_000650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001211265.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CtsR family transcriptional regulator"
                     /protein_id="HGR0068998.1"
                     /translation="MRFKNTSDHIEAYIKAILDQSGIVELQRSQLADTFQVVPSQINY
                     VIKTRFTESRGYLVESKRGGGGYIRIGRIEFSSHHEMLRDLLYSIGERVSQEIYEDIL
                     QLLVEQELMTKQEMNLLESVALDRVLGEEAPVVRANMLRQVIQEVDRKGK"
     gene            36892..39324
                     /locus_tag="ACL29Z_000651"
     CDS             36892..39324
                     /locus_tag="ACL29Z_000651"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001109706.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit"
                     /protein_id="HGR0068999.1"
                     /translation="MNYSKALNECIESAYMVAGHFGARYLESWHLLIAMSNHSYSVAG
                     ATLNDYPYEMDRLEEVALELTETDYSQDETFTELPFSRRLQVLFDEAEYVASVVHAKV
                     LGTEHVLYAILHDGNALATRILERAGFSYEDKKDQVKIAALRRNLEERAGWTREDLKA
                     LRQRHRTVADKQNSMANMMGMPQTPSGGLEDYTHDLTEQARSGKLEPVIGRDKEISRM
                     IQILSRKTKNNPVLVGDAGVGKTALALGLAQRIASGDVPAEMAKMRVLELDLMNVVAG
                     TRFRGDFEERMNNIIKDIEEDGQVILFIDELHTIMGSGSGIDSTLDAANILKPALARG
                     TLRTVGATTQEEYQKHIEKDAALSRRFAKVTIEEPSVADSMTILQGLKATYEKHHRVQ
                     ITDEAVETAVKMAHRYLTSRHLPDSAIDLLDEAAATVQNKAKYVKADDSDLSPADKAL
                     MDGKWKQAAQLIAKEEEVPVYKDLVTESDILTTLSRLSGIPVQKLTQTDAKKYLNLEA
                     ELHKRVIGQDQAVSSISRAIRRNQSGIRSHKRPIGSFMFLGPTGVGKTELAKALAEVL
                     FDDESALIRFDMSEYMEKFAASRLNGAPPGYVGYEEGGELTEKVRNKPYSVLLFDEVE
                     KAHPDIFNVLLQVLDDGVLTDSKGRKVDFSNTIIIMTSNLGATALRDDKTVGFGAKDI
                     RFDQENMEKRMFEELKKAYRPEFINRIDEKVVFHSLSSDHMQEVVKIMVKPLVASLAE
                     KGIDLKLQASALKLLANQGYDPEMGARPLRRTLQTEVEDKLAELLLKGDLVAGSTLKI
                     GVKAGQLKFDIA"
     gene            39645..40298
                     /gene="rr06"
                     /locus_tag="ACL29Z_000652"
     CDS             39645..40298
                     /gene="rr06"
                     /locus_tag="ACL29Z_000652"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001024075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system response regulator RR06"
                     /protein_id="HGR0069000.1"
                     /translation="MNILVADDEEMIREGIAAFLTEEGYHVIMAKDGQEVLEKFQDLP
                     IHLMVLDLMMPRKSGFEVLKEINQKHDIPVIVLSALGDETTQSQVFDLYADDHVTKPF
                     SLVLLVKRIKALIRRYYVIEDIWRYQDVTVDFTSYKAHYKNEEIDLKPKELLVLKCLI
                     QHKNQVLSREQILEEISKDVADLPCDRVVDVYIRTLRKKLALDCIVTVKNVGYKISL"
     gene            40295..41635
                     /gene="hk06"
                     /locus_tag="ACL29Z_000653"
     CDS             40295..41635
                     /gene="hk06"
                     /locus_tag="ACL29Z_000653"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000594665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system sensor histidine kinase
                     HK06"
                     /protein_id="HGR0069001.1"
                     /translation="MIKNPKLLTKSFLRSFAILGGVGLVIHIAIYLTFPFYYIQLEGE
                     KFNESARVFTEYLKTKTSDEIPSLLQSYSKSLTISAHLKRDIVDKRLPLVHDLDIKDG
                     KLSNYIVMLDMSVSTADGKQVTVQFVHGVDVYKEAKNILLLYLPYTFLVTIAFSFVFS
                     YFYTKRLLNPLFYISEVTSKMQDLDDNIRFDESRKDEVGEVGEVGKQINGMYEHLLKV
                     IHELESRNEQIVKLQNQKVSFVRGASHELKTPLASLRIILENMQHNIGDYKDHPKYIA
                     KSINKIDQMSHLLEEVLESSKFQEWTECRETLTVKPVLVDILSRYQELAHSIGVTIEN
                     QLTDATRVVMSLRALDKVLTNLISNAIKYSDKNGRVIISEQDGYLSIKNTCAPLSDQE
                     LEHLFDIFYHSQIVTDKDESSGLGLYIVNNILESYQMDYSFLPYEHGMEFKISL"
     gene            41718..42245
                     /locus_tag="ACL29Z_000654"
     CDS             41718..42245
                     /locus_tag="ACL29Z_000654"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000241939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isoprenylcysteine carboxyl methyltransferase
                     family protein"
                     /protein_id="HGR0069002.1"
                     /translation="MVLAIILVTFLIRLIFLKRSIENEKRILSNGGKEFGVENTKRLT
                     MAHIVFYLSCLVEAMVHKTIFDGMGMVGLVLLIFSMLMLMLVIHLLGDIWTVKLMLVN
                     NHKYVDHILFRTVKHPNYFLNILPELIGLTLLSHAYVTFVLVFPVYAVILYRRIAEEE
                     KLLHEVIIPNGSIKR"
     gene            42324..>44295
                     /gene="pspC"
                     /locus_tag="ACL29Z_000655"
     CDS             42324..>44295
                     /gene="pspC"
                     /locus_tag="ACL29Z_000655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000458100.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal surface protein PspC,
                     choline-binding form"
                     /protein_id="HGR0069003.1"
                     /translation="MFASKSERKVHYSIRKFSIGVASVVVASLFLGGVVHAEGVRSGN
                     NSTVTSSGQDISKKYADEVESHLQSILKDVNKNLKKVQHTQNADFNKKLSKIKTKYLY
                     ELNVLEEKSEAELTSKTKETKEELTAAFEQFKKDTLSTEPEKKVAEAKKKVEEAKKKA
                     EDQKEKDRRNYPTITYKTLELEIAESDVEVKKAELELVKVKANEPRDEEKIKQAEAKV
                     ESKQAEATRLKKIKTDREQAEATRLENIKTDREQAEEEAKVKDEPKKRTKRGVLGEPA
                     TPDKKENDAKSSDSSVGEETLPSPSLKPEKKVAEAEKKVEEAKKKAEDQKEEDRRNYP
                     TNTYKTLELEIAESDVEVKKAELELVKEEAKEPRNEEKVKQAKAEVESKQAEATRLEK
                     IKTDRKKAEEEAKRKAAEEDKVKEKPAEQPQPAPAPQPEKPAPKPEKPAPAPKPENPA
                     EQPKAEKPADQQAEEDYARRSEEEYNRLTQQQPPKTEKPAQPSTPKTGWKQENGMWYF
                     YNTDGSMATGWLQNNGSWYYLNSNGAMATGWLQNNGSWYYLNANGSMATGWLQNNGSW
                     YYLNANGSMATGWLQNNGSWYYLNANGSMATGWLQYNGSWYYLNANGDMATGWLQYNG
                     SWYYLNANGSMVTGWLQYNGSWYYLNANGSMAT"
BASE COUNT        14053 a         7255 c         9564 g        13423 t
ORIGIN      
        1 ttttagacaa tatgtttaaa aaaggagaaa ctatgtttaa agaatggaaa gcaatttaaa
       61 aaaaaacaac ctttattatt gtcatgatcg ggatttctct tattccagct ctgtacaata
      121 tcatattttt gtcatcaatg tgggatccat atgggcaatt gtctgactta cctgtggcag
      181 ttgtaaataa tgataaagag gcttcctata atggtaatac tatggcaata ggaaaagaca
      241 tggtgtccaa tttaaaagaa aataaaacct tggattttca ttttgtagat gaagaggaag
      301 gaaagaaggg attggaagat ggcgattact atatggtagt gactttacca agtgatttat
      361 ctaaaaaaac aactacatta tccaatattc aatcgacagc agcttatcaa tcattgacaa
      421 gtgagcaaca aactgggata agtgattctg tatctcaaaa ttcaactgat agtattcaat
      481 cggctcagtc aattgtagct ttagtacaag gtttacaggg aagtttagaa aacttacaaa
      541 atcaatcttc taatctttcg actttaaaaa atcaagctaa tcaagtatta cctattactt
      601 ctacttcttt gataggattg tcaagtggat taacagagat acaaggagct gttactagca
      661 aattagttcc tgccagtcag ttgattgcat caggtgtaaa cgcatatact acaggtgttg
      721 ataaagtttc tcagggcgca agtcaactaa gtgaaaaaaa tgccaccttg acaggtagtt
      781 tggataaact agtttcaggc tcaaacacct tgacacaaaa atcttctaga ttgacagcag
      841 gatctgggca attagcagac aaatccagtc agttactttc aggtgcttct ccattagaga
      901 atagagctaa taaattggca gatggatctg ggaaactagc agaaggtgga acaaagttaa
      961 cttctggatt ggaagattta cagacaggac ttgcttcttt aggacaagga ctaggtaatg
     1021 ctagtgatca actcaaatca gtatcaacag aatctaaaaa tgcagagatt ttgtcaaatc
     1081 cactcaatct ttcaaaaaca gacaatgatc aagttcctgt aaatggaatc gcaatagctc
     1141 cttatatgat atcagttgct cttttttttg cagcaatatc aacaaatatg atatttgcga
     1201 aattgccttc aggacgtcat ccagagagcc gttgggcttg gttgaaatct tgagctgaaa
     1261 taaatggtat tatagctgtt ttggcaggaa ttttggtata tggaggagtt cagcttattg
     1321 gtttaactgc taatcatgag atgagaatat ttattctcat catcctaaca agtttagtat
     1381 tcatgtctat ggtgaccact ttagcaacgt ggaatagccg tataggagct tttttctcac
     1441 ttattttgct tttactacag ttagcatcaa gtgcaggtac ttatccactt gctttgacaa
     1501 atgatttctt tagatctatt aatccctggt taccaatgag ctattcagtt tcgggattac
     1561 gacaaacaat ctctatcaac aagtcatttt cctagctgtc atactagctc tatttactgg
     1621 tttaggtatg ctagcctatc aacataagaa aatggaagaa gattaaaaaa atcgaccgat
     1681 taactggtcg attttttatg ccttagatga ctttcgtctg tgattataga ttccaaatag
     1741 taagagagaa gtaaaggaac agattgctcc agtaataaaa ccattgggaa tgaaggaaag
     1801 tgtaatagtt cctttcccct tgggaatgtc aactttcata aatccagttt gagcttgttt
     1861 aatttctatt ttcttaccat cttggtaggc agaccaacct ttgtcataag gaatggtgaa
     1921 gaaaatagat gtatcttgtt ggacatcata tgtagcaaaa accttgtttt tagaagttga
     1981 tactgtgaca ggttgttttt taattttttg aattgcctcg gtgaaagttt tggtatctaa
     2041 acgatagaag gtaggagatt caaatgatac ttgtgaattt ccagggaaac taacattgat
     2101 attgaaagtt tttttctctt tagtatatcc tagattaaag aaggagaaga cattatcagt
     2161 tgtaaaagtc tttttttcac catttacaag tatgtcaacc ttcttttgtt tatcgttaga
     2221 aaagtgaagg tttatgaaag agagataaac ttggctgttt tctggaactt caatttgata
     2281 ctggattgct gcatcttcat ttgaagaact tgtgacacta atcaaatcat tagtattttc
     2341 tattttttct gttttttcat aaggtattgg agaaaaataa tcaaaattga cgttagcaag
     2401 ttgatttaaa aatgaggcct gattatccaa ggtatgttca ttgaacttga catcattgta
     2461 aacagattga ctagcaactg caatcggaag agagtattga ttttcatata gggtaagatt
     2521 atctttttga tagatatctt taaagccata cttatcaata ggactgtctg agatattgta
     2581 ctggatacca aataaactat cagccaaaat actattattt gcatatcgga gattgagatt
     2641 agtcccagag gatttaaaac caagtttatc taaagtagag cttgatgaac gatttcgaac
     2701 agatgaaaat tgagagattc cattgtagtt gaatttcata ctgtcatttc ctgtctgagt
     2761 ttgtagtttt tcagtacgag taaattgatt tccaatatat gttgagaaag attccatagc
     2821 tgggatatct cgactataag cacttcgaga agcaaatccc cattccttag caattccgtc
     2881 catttgagat gaagcattta aactcatttc aaccagtata aataaagaga ttagaatggc
     2941 aaatagattc acagatataa actttttgat aactgcaagg agtaaaagag aatagacaac
     3001 caaaaattca agagtaagca gaatattcaa atctgttaaa aaagaataat gcgattttag
     3061 atagatggta gctaaaaatc ctgctactac aagaaaaagc gaaactaaaa aattccagac
     3121 tttaagttct ttcagacgct ttaagacttc tgctgctgtg taaattaaca aggtagagaa
     3181 aatccaagca taacgatgta aaaacatgtt tggagtatgc atgccttgcc aaaataagtc
     3241 aagagcttct atgtaaaagc ttgcaattag aaatgcaaag aatattacat atatgagttt
     3301 cacgtgaaac ttaatagatt tcagcgtaaa aaataaaatg gtcaaaataa agggaaatag
     3361 tccaacaaaa atcattggga tggccccata ctttgttgtg tcaaaggaac caatgaattg
     3421 cttagcaaag agatcaagat accagctact ttcagtttga aactttgtaa cttcagtcaa
     3481 tttttcccca tgtgtctgta aatcaaatag agtgggaaga gtcataatca aactagccat
     3541 accagctaaa aaggagataa ctatgaaatc aagaacagat gattttcgag tcttaaagtc
     3601 ccacgaaatt tgacagagat accagaaaat aagaaacaat actgtcatat atccaaaata
     3661 ataattttga ataaataaga ttgacagact tgtaaagtac aataggagtt tcttttcagt
     3721 tatcagtaga tgtaaaccag ttataattaa aggaatcaag ataaaaacat ctagccaggt
     3781 ttttatctct aattgactga cagtgaaact catcagagca taggaagtag ataaggctag
     3841 ttttaaagtc tgagggatag attgaaataa tttattcaaa ctaaaaaagg ttgacagacc
     3901 aatcaatcca aattttaaga gagtggtcag atagacagca tctggcatat tcgttagatc
     3961 aaaaaagtaa actagaggcg cgagaaaact acccaagtaa taactagata gggcatagaa
     4021 gtttagccct agaccacttg taaaggtgta aaacagacta ctatttccat gtaggatatt
     4081 tcgtaaggct acatcaaaaa taacgtattg atgaaagcca tctcctaata gaggagagtt
     4141 gtcgctattc cagtagatac cttgagatag atatactcca gacataatca ctacaggaat
     4201 gatgaaagaa ataaaatagg ttcgatatgt ttttaaaaat gatttcatgt tacctcgtag
     4261 aatgatagaa aactcagttg gttaacccaa ctgagttttg aagttttatt tagtctttcc
     4321 aaagttcttt aacttttgct tgtacttctg cattttctag gaattcatcg taggtttcat
     4381 cgatacggtc aatgacgcca tttttagata agacaatgat atggttagcc aaagtttgaa
     4441 taaattcgtg gtcatggcta gcaaagatga ttgattcttt aaagtttttc aatccatcat
     4501 tcaagcttga gatagattcc aagtccaagt gatttgttgg atcatcaagt acaaggacat
     4561 ttgattttaa gagcatgagt tttgaaagca tgacacgaac tttttctccc cctgacaaga
     4621 catttacagg tttgttaact tcatctccag agaagagcat acggccgagg aagccacgta
     4681 ggaaagtatt gtcatcttct tctttacttg cgaattgacg caaccagtca agaattgatt
     4741 ctcctcctgc aaaatcagct gagttatctt ttggtaggta agattgacta gttgtaactc
     4801 cccacttgac agttccttca tagtcaatat ctcccatgat tgcacgaatt aatgcagtcg
     4861 tttgaatatc attttgtcca ataagtgctg tcttatcatc tggacgcaag atgaaactaa
     4921 tattatccaa gatagtttca ccatcaatct ttacagttag attttctact gtcaagagat
     4981 cattaccaat ctcacgttcc gctttaaagt tgataaatgg atatttacga ctagatggca
     5041 caatctcttc tagctcaatc ttatcaagca ttttcttacg tgatgttgcc tgccttgact
     5101 tagaagcatt ggcagagaaa cgagcaacga attcttgcaa ttgtttaatt ttttcttctg
     5161 ctttagcatt acggtctgct agcaatttag cagcaagctc agaagattcc ttccagaagt
     5221 cgtagtttcc gacatagagt ttgatttttc caaagtcaag gtcggccatg tgagtacaaa
     5281 ctttgtttaa gaagtgacgg tcgtgggata ctacgataac tgtgttatca aagtcaatta
     5341 agaagtcttc taaccaagta atcgattgga tatccaaacc gttagtaggc tcgtccaaga
     5401 gaagaacatc tggtttacca aaaagtgctt tggcgaggag aacctttact ttttcaccgt
     5461 tggccaattc gctcatgttt tggtagtgta attcttctgg aatgtttagg ttttgaagta
     5521 gttgagaggc ttcactctct gcttcccaac ctccaagttc ggcaaactct ccttcgagtt
     5581 cggcagcacg aaccccgtcc tcgtctgaga aatcttcctt catgtagata gcatctttct
     5641 ctttcatgat gctataaagt ttttcatttc ccatgataac gacatcaatg gcacgttcat
     5701 cttcgtagtc aaagtgattt tgacgaagaa cagagagacg ttcatctgga ccaagagaga
     5761 tgtgaccagt agtaggttcg atatctccag ctaaaatttt taaaaaggtt gattttccgg
     5821 caccattagc accgattaat ccgtaagtat ttccttctgt aaatttgata ttgacatcat
     5881 caaaaagttt gcgatcacta aaacgtagtg aaacatcaga tactgtaagc aatatttttc
     5941 tcctatatgt gtaatatatt tattctacta gaaaatacag aaatattcaa atttttattt
     6001 gtcaattttg tgtcaattat atttacagta tcctttacac aaatctgtaa aaagcaaggc
     6061 tgatttattt tgataaatta cggttatttc attaaaaaaa tgctataatt gaaaggacta
     6121 tatcgaagga gaacaaaatg actaaaccca ttattttaac aggagaccgt ccaacaggaa
     6181 aattgcatat tggacattat gttggaagtc tcaaaaatcg agtattatta caggaagagg
     6241 ataagtatga tatgtttgtg ttcttggctg accaacaagc cttgacagat catgccaaag
     6301 atcctcaaac cattgtagag tctatcggaa atgtggcttt ggattatctt gcagttggat
     6361 tggatccaaa taagtcaact atttttattc aaagccagat tccagagttg gctgagttgt
     6421 ctatgtatta tatgaatcta gtttcgttag cacgtttgga gcgaaatcca acagtcaaga
     6481 cagagatttc tcagaaagga tttggagaaa gcattccgac aggattcttg gtctatccaa
     6541 tcgctcaagc agctgatatc acagctttca aggctaatta tgttcctgtt gggacagatc
     6601 agaaaccaat gattgagcaa actcgtgaaa ttgttcgttc ttttaacaat gcatataact
     6661 gtgatgtctt ggtagagccg gaaggtattt atccagaaaa tgagagagca gggcgtttgc
     6721 ctggtttaga tggaaatgct aaaatgtcta aatcactaaa taatggtatt tatttagctg
     6781 atgatgcgga tactttgcgt aaaaaagtaa tgagtatgta tacagatcca gatcatatcc
     6841 gcgttgagga tccaggtaag attgagggaa atatggtttt ccattatcta gatgtttttg
     6901 gtcgtccaga agatgctcaa gaaattgctg atatgaaaga acgttatcaa cgaggtggtc
     6961 ttggtgatgt gaagaccaag cgttatctac ttgaaatatt agaacgtgaa ctgggtccta
     7021 ttcgtgagcg ccgtattgaa tttgctaagg atatgggaga agtttataat atgattcaaa
     7081 aaggtagtga aagagcgcgt gaagttgcgg gtcaaaccct atctgaggta aaaggggcaa
     7141 tgggacttca ttactttaac taagtttatt ttacaagaaa ctatcatttc tatctcgaag
     7201 aaaagatagt tttttattta cccctgtaac atttgacaaa tttgtataga atggtatgat
     7261 agatacaata taaaaagagt caagctcaaa aagaaagaaa agaggaaact tcgaatgtct
     7321 aattgggaca ctaaattttt gaaaaaaggt tttacctttg atgatgtatt gcttattcca
     7381 gctgaaagtc atgtgttgcc taacgatgca gatttaacaa ctaaattggc agataatttg
     7441 actttaaata tcccaattat taccgctgcc atggacacag ttacagagag tcaaatggcc
     7501 attgctattg ctcgtgcagg tggtctcgga gttatccata aaaacatgtc aattgctcaa
     7561 caagcagacg aggttcgtaa ggtaaaacgt tctgaaaatg gagttattat tgatccgttc
     7621 ttcttgacgc ctgaacatac aattgctgaa gcagatgagc ttatgggtcg ttaccgcatc
     7681 agtggtgttc cagttgttga aacacttgaa aatcgtaaat tggttggtat tttgacaaac
     7741 cgagatcttc gttttatttc agattataat caaccaattt caaaccatat gactagtgaa
     7801 aatcttgtta ctgctcctgt gggtacggat cttgcaacgg ctgagagtat tcttcaagag
     7861 catcgtattg aaaaacttcc gttggtcgat gaagaaggca gtctttctgg tttgatcact
     7921 atcaaagata ttgaaaaagt tattgagttt ccaaatgcgg ctaaagatga gtttggtcgt
     7981 cttctagttg caggtgcagt aggtgttact tcagatacat ttgaacgtgc agaggctctt
     8041 tttgaggcag gagcggatgc gattgttatt gatactgcac atggtcattc tgcaggtgtc
     8101 ttgcgtaaaa ttgccgagat tcgtgctcat ttcccagatc ggactttgat tgctggaaat
     8161 attgctactg ctgaaggtgc acgtgccctt tatgaagcgg gtgtagacgt tgttaaggtt
     8221 ggtattggac caggttctat ctgtactact cgtgtgattg ctggtgttgg tgttccgcaa
     8281 gtaacagcta tctacgatgc tgcagctgtt gcgcgcgaat atggtaaaac gattattgct
     8341 gacggtggga tcaagtattc tggagatatt gtaaaagcac ttgctgcagg tggaaatgct
     8401 gttatgcttg gatctatgtt tgctggaact gatgaagctc caggcgaaac tgaaatcttc
     8461 caaggacgta aattcaagac ttaccgtggt atgggatcaa ttgctgctat gaagaaaggt
     8521 tcaagcgacc gttatttcca aggttctgtc aatgaagcaa acaagcttgt tccagaagga
     8581 attgaaggtc gtgttgctta taaaggagcg gcagctgata ttgttttcca aatgattggt
     8641 ggtattcgct ctggtatggg ttactgtggt gcagctaacc ttaaagaact acacgataat
     8701 gctcaattta ttgaaatgtc tggtgctggt ttgaaagaaa gccatcctca tgatgtgcaa
     8761 attactaatg aggcaccaaa ttattctatg taaaaaacaa tgaaaagaac tccagtgaaa
     8821 acaggagttc ttttacaatg ttgtcaattt ccatttacag cagctttacc atcctgaata
     8881 gtgaagatac ttagattttc tggcagattt tgaagatggt ctaagcttgt tgttgtgata
     8941 aaggtttgga ttgattgaga aatcgtttct aataatttta actgtctagt gttgtcaagt
     9001 tcactcatca catcgtcaag cagtaatatc ggagattctg tggtaatgct ttccattaat
     9061 tcgatttctg ctaattttat cgagaggacg agactacgat gttgaccttg gcttccgaaa
     9121 ctagcatcca tcccatttat ataaaaagaa atgtcatctc gatgaggacc gacaccagta
     9181 ttctttttaa ataaatctct ggatctactt ttttctaaag caattttgaa agattcggat
     9241 aagttttgtt tgtcagttat attgacagaa gattgatagg atattgacaa ctcttcgatc
     9301 tgattagaga gttcaaaatg tttcttacgc ccaaatgatt ctagtttttt tatgaaatct
     9361 aagcggtgat tcattacacg acatccataa tcaactagct gatcatctaa cacagaaagg
     9421 aatgtttcat ctattttttg atctgatttt aggtaagtgt ttctttgctt taggatgtgg
     9481 ttataattgg ttaagtcaga taagtagatt ggcttaattt gcccaagttc catatcaatg
     9541 aattttcgtc gaatcgaagg tgctccttta attagttgta aatcttcagg agcaaataag
     9601 acaacattca tgtgtcctac ataatctgaa aggcgtgcct gttttaagtg attaactttt
     9661 gttacacggc ctttttgtgt tagttcgatt tctaggggaa tggatccagt ttttttctga
     9721 acgagacctg aaagatgaag ttgttcctca tcaaaatgaa tgagattttt atctgttcga
     9781 gttcgatgac tacgcgttaa ggctaaaaaa tagatagcct ctaacatgtt tgtttttcct
     9841 tgtgcattac gtcccaaaaa gacattcaat ttaggattaa agtctatttt cgtttctttg
     9901 taattacgaa aagtcttgag agatagatgt tgtagccaca tgattatcta ccagggaatc
     9961 gtggagcttg ttggctttta ggtgatgaag caggtttcga tttgtctttt ttaactccct
    10021 tattcatctt tttgacaagt ttagcgatcc gttctttttc aactttatca gcttggtatt
    10081 catcttgttc ttcagaagta ggttgtgtca acaagatgtc aatgttcatg tcagggatgt
    10141 caactttatc gccaatacga agtttttttc cacgacgact ctctaattcc ctattaaagt
    10201 aaacagaatg ttcagagaga aatgatttaa tagctcctcc gctatgtgta attccaagtt
    10261 ctttgagtag tgcttggagg gtaataaatt cttcaaataa tttgtattcc ataattcacc
    10321 tcaatctttg gtattatacc atattttcct aaaaatagtg agagagacag agagaaatgt
    10381 aagcgatttt tatttcaaaa gtgttacagg gaataagaaa atttcaggtt ttcgtgatat
    10441 aatagaagtc tgtatataag gaggtaaatc atggagttag tgcatggaat ttcaacacat
    10501 tttatccaat caaaaaagtt taaaacaaac aaaattaccg tgcgttttac cgctccatta
    10561 tcccttgata cgattgcagg tcacatgttg agtgcaagta tgctagagac tgctaatcag
    10621 atgtacccca cttctcaaga tttgaggaga cacttggcca gtctatacgg tacagatatg
    10681 tcaaccaatt gtttcagaag agggcaaagc cacattatag aattgacatt tacctatgtt
    10741 cgtgatgagt ttttaagtag gaaaaacgtg ctaacctctc agattttgga acttgtaaaa
    10801 gaaactcttt tttcacccgt agtagttgat aatgggtttg atccggcctt atttgaaatt
    10861 gagaaaaaac aattgctagc aagtttagca gctgatatgg atgattcttt ttattttgca
    10921 cataaagaat tggataaatt gttttttcat gatgaacgtc ttcaattgga atatagtgat
    10981 ttacgaaatc gtattttagc tgaaactcca caaagttctt attcttgttt ccaagaattt
    11041 ttagccaatg atcgaataga tttctttttc ctaggtgatt ttaatgaggt tgaaattcaa
    11101 aatgtattag aatcatttgg ctttaaaggt cgaaaaggag atgtgaaggt tcagtattgt
    11161 caaccttatt ctaatatcct tcaggaaggt atggttcgga aaaatgtggg acaatccatt
    11221 ttggaattag gttatcatta ccgttctaaa tatggtgatg agcaacattt acccatgatt
    11281 gtaatgaatg gtttacttgg tggatttgct cattctaagc tctttacaaa tgtccgtgaa
    11341 aatgctggat tagcttatac catttcaagt gagcttgatt tatttagtgg attcttgagg
    11401 atgtatgctg gtatcaatcg agaaaatcgt aaccaggctc gtaaaatgat gaataatcaa
    11461 ctgcttgatt taaaaaaagg ttattttaca gagtttgagt taaatcagac caaggaaatg
    11521 attcgttggt cgttgttact ttctcaagat aatcaatctt cattgattga acgtgcttat
    11581 caaaatgcct tatttggaaa atcttcagca gactttaaaa gttggattgt aaagcttgaa
    11641 cagattgaca aagatgctat ttgtagagta gctaataatg tgaaactaca agcgatttac
    11701 tttatggaag gaatagaatg acaaaggttg tttttgaaga aaaatactat ccagctgtaa
    11761 aagaaaaggt ttatcgaact cgtttggcca atggattgac agttgctctt ttgcctaaaa
    11821 aggaatttaa agaggtttac gggagtgtca ctgtacagtt tggttcggta gatacgtttg
    11881 tcacagaagt tgacggagat gtaaaacaat atcctggagg aattgctcat tttcttgaac
    11941 ataaattatt tgagagagaa gattctagtg atttgatgtc ggcttttacg agtctaggtg
    12001 cagatagtaa tgcctttaca agctttacaa aaacaaacta tcttttttca gcaacggatt
    12061 attttttaga aaatttagat ttacttgatg aattggtaac atcagcacac tttactgaag
    12121 cttccattct gacagagcag gatattattc agcaagaacg agaaatgtac caagatgatc
    12181 cagattcgtg tttattcttt tcaactttag cgaatttgta tcctggtaca cctttagcaa
    12241 ctgatatagt tggaagtgag gagtccattt cccaaatcaa tctaactaat ttgcaagaaa
    12301 attttacaaa gttttacaaa cctgtaaaca tgtctctgtt tttagttggt aattttgatg
    12361 tggagcgagt acaggactat tttgaaagca aagaactgaa agattcagat tttcaggaag
    12421 tagcaagaga aaagttgttt ttacagcctg taaagccaac agatagtatg agaatggaag
    12481 tatcttctcc caaactagcg attggagtta gaggtaagcg agaagtttct gaagcggatt
    12541 gctatcgaca tcatatttta ttaaagttat tgtttgcaat gatgtttggt tggacttcgg
    12601 atcgttttca aaaatgttat gaatcaggta aaattgatgc atccttatct ctggaagttg
    12661 aagtaacaag tcgctttcat tttgtcatgt tgacaatgga tacgaaagag ccagttgctt
    12721 tgtctcatca atttaggaag tctattcgta attttacaaa ggatttagat attacagagg
    12781 aacatttaga tattatcaaa agagagatgt ttggcgaatt tttcagtagc atgaactctc
    12841 ttgaatttat tgcaacgcaa tatgatgctt ttgaaaatgg tgagacaatt tttgatttgc
    12901 cgaaaatttt acaggaaatt actttagagg atgtccttga tgctggacat catttaatag
    12961 atgatggtga catagttgat tttacaatat tcccatcgta gtaacctatt ataatagaca
    13021 ctagaaagaa gggatgacaa gtatgagaaa aaaaacaatt ggagaggttt tacgattagc
    13081 tagaatcaat cagggattga gtttagatga attgcagaaa aagacagaaa tccagttaga
    13141 tatgttggaa gcaatggaag cagacgattt cgatcaactt ccaagtcctt tttacacgcg
    13201 ttctttcttg aaaaaatatg catgggctgt tgagttagat gaccaaattg ttttggatgc
    13261 ttatgattct gggagtatga ttacttatga ggaagtagat gttgatgaag atgagttgac
    13321 aggtcgtaga cgttcaagta agaaaaagaa gaaaaaaaca tcatttttac ctttatttta
    13381 ttttatcctt tttgctttat cgattttaat ttttgtgact tattatgttt ggaactatat
    13441 tcaaactcaa ccagaggagc cttctctttc taattacagt gtggttcaat caacaagttc
    13501 aactagctct gttccccact cctcaagtag tagttcttct agtatagaat cagctataag
    13561 tgtatcaggc gaaggaaatc atgtagaaat cgcttataag acaagtaagg aaacagttaa
    13621 attgcaattg gcagtttcag atgttacaag ttgggtcagt gtttcagaaa gcgaacttga
    13681 gggcggtgta accttatcgc caaagaagaa aagtgcagaa gcaacagttg caactaaaag
    13741 tcctgtaaca attacgttag gtgttgtaaa aggtgttgat ttgacagtag ataatcagac
    13801 tgttgattta tcgaaattaa cagctcagac tggacaaatc actgtaacct ttactaaaaa
    13861 ttaaggaaaa acgaatgaaa aaagaacaaa ttcccaatct cttaacaata ggtcgaattc
    13921 tctttatacc tatttttatc tttattttaa cgataggaaa ttcgatagag agtcatatag
    13981 ttgcagctat tatctttgct gttgccagta ttaccgacta tttagatgga tatttagctc
    14041 gtaaatggaa tgtggtcagt aattttggta aatttgcaga tcctatggcg gataagttac
    14101 tagttatgtc ggcttttatt atgttgattg agttaggtat ggctccggct tggattgttg
    14161 cagtgattat ctgtcgtgag ttagctgtga caggtttaag gcttttattg gttgaaactg
    14221 gtggaacaat tttagcagca gcaatgcctg gaaaaattaa aacttttagt cagatgtttg
    14281 ccattatttt cttgctatta cattggactt tgcttggtca agttctactt tatgtagcct
    14341 tatttttcac tatctactct ggctatgact atttcaaggg tagtgcctat gtatttaaag
    14401 ggacatttgg ttcgaaatga aatcaataat tgatgtaaaa aatctttctt ttcgctataa
    14461 agaaaatcag aactactacg atgtgaagga tattacgttt cacgtgaaac gtggagaatg
    14521 gctttcgatt gtagggcata atggtagtgg taaatcaacg acggttcgat taattgatgg
    14581 cttactggaa gcagaatccg gagagattgt aattgatggc caacgtttga ctgaggaaaa
    14641 tgtttggaat atacgtcgtc aaatcggtat ggtttttcaa aatccagaca atcaatttgt
    14701 tggagcgact gttgaagatg atgttgcttt tggtttggaa aatcagggac tttctcgtca
    14761 agaaatgaaa aagagagtgg aagaagctct ggctttagtt ggcatgttgg actttaaaaa
    14821 gagagagcca gcgcgtctat caggtggcca aaagcaacgt gtggccattg caggtgttgt
    14881 agccctaaga ccagctattt taatcttaga tgaagcaacg agtatgttgg atcctgaggg
    14941 gcgtagagaa cttattggga cagtaaaagg aattcgaaaa gactatgata tgacggtcat
    15001 ttctattacc catgatttgg aagaagtcgc catgagtgat cgcgtattgg tcatgaaaaa
    15061 aggggaaatt gaatcaacta gtagtccaag ggagcttttc tctcgaaatg atttagatca
    15121 aattggatta gacgatcctt ttgctaatca attaaaaaaa tttttgagcc agaatggcta
    15181 taatttacct gaaaattatt tgacagaaag tgagctagag gataagctat gggaattgct
    15241 ctagaaaatg tgaattttac atatcaagaa ggtactccct tagcttcagc agctttgtcg
    15301 gatgtttctt tgacgattga agatggctct tatacagctt taattgggca cacaggtagt
    15361 ggtaaatcaa ctattttaca actcttaaat ggtttattgg tgccaagtca agggagtgtg
    15421 agggtttttg ataccttaat cacctcgact tctaaaaata aagatattcg tcaaattaga
    15481 aaacaggttg gcttggtatt tcagtttgct gaaaatcaga tttttgaaga aacggttttg
    15541 aaggacgttg cttttggacc gcaaaatttt ggagtttctg aagaagatgc tgtgaagact
    15601 gcgcgtgaga aactggctct ggttggaatt gatgaatcac tttttgatcg tagtccgttt
    15661 gagctgtcag ggggacaaat gagacgtgtt gccattgcag gcatacttgc catggagcca
    15721 tctatattag tcttagatga gccaacagct ggtctagatc ctctagggag aaaagagttg
    15781 atgaccctgt tcaaaaaact ccaccagtca gggatgacca tcgtcttggt aacgcatttg
    15841 atggatgatg ttgctgaata tgctaatcaa gtctatgtaa tggaaaaggg acgtttagta
    15901 aaggggggca aaccaagtga tgtctttcaa gacgttgttt ttatggaaga agttcagttg
    15961 ggagtaccta aaattacggc cttttgtaaa cgattggctg atagaggcgt gtcatttaaa
    16021 cgattaccga ttaagataga ggagttcaag gagtcgctaa atggatagta tgattttggg
    16081 gcgttatatc ccaggggatt cgattgttca ccgattggat ccacgtagca aattgcttgc
    16141 tatgatgcta ctgattttga ttgtgttttg ggctaataac cccttgacga atctgattct
    16201 ttttatagcg acagggatat ttattgcctt gtcaggagta tctctttcat tttttattca
    16261 gggcttgaag tctatgtttt tcttgattgc cttcacaact atttttcaac tatttttcat
    16321 ttctaatggg aatgttttat ttgagttttc gtttgtgaga atcacggatt atgctttgca
    16381 acaagctggg attatttttt gtcgctttgt attgattatt ttcttttcaa ctttgttaac
    16441 cttaacaacc atgcctttaa gtttggcatc agctgtcgaa gctttattag cacctttaaa
    16501 gcgtgtgaaa gttccagttc atgaaattgg attgatgctg tctatgagtt tgcgttttgt
    16561 cccaaccttg atggatgata cgactcggat tatgaatgca cagaaagctc gtggagtgga
    16621 ttttggagaa ggaagcatcg ttcaaaaagt aaaggcgatg attcccattt tgattcctct
    16681 ttttgcgaca agtttaaaac gtgcagattc cttggctatc gctatggaag cgcgtggcta
    16741 tcagggtgga aaaggcagaa gtcaataccg acaattgaaa tggactctaa aggatacgct
    16801 gaccattctt gttattctcg tacttggttg ttgtttattt ttcttaaaat cttagtagct
    16861 ttcaggaatt gataaaaagt tactgtaaca gtttttgata gaaaggtagg gatatgaacc
    16921 gttttaaaaa atcaaaatat gtcattattg tttttgtcac tgttctgctt gtgtcagctc
    16981 tcttagcgac gacttattca agtacaattg tgacaaaatt aggagatgga atctcattgg
    17041 ttgatagagt tgtacaaaaa ccttttcagt ggtttgattc tgtcaaatca gatttggctc
    17101 atttgacacg aacatataat gaaaatgaaa gtttgaagaa acagctttac caattagaag
    17161 ttaaatcaaa tgaggtggaa agtttaaaga cagaaaatga acaactgcgc caattgcttg
    17221 atatgaagtc taaattgcaa gccacaaaga ctttagcagc agatgttatt atgcgttctc
    17281 cggtatcttg gaagcaggag ttgaccttag atgcaggtag atcaaaaggt gcttctgaga
    17341 acatgttagc tattgcaaat ggtggcttga ttgggagtgt ttcaaaagta gaggagaact
    17401 ctactatagt caaccttctg acaaatacgg aaaatgctga taagatttct gttaaaattc
    17461 aacatggctc tattacaatt tatggaatta ttattggcta tgacaaggaa aatgacgttc
    17521 ttaaaattag ccaattaaat agtaatagcg atattagtgc gggagataag gtgactactg
    17581 gtggattagg aaactttaac gttgctgata ttcctgttgg tgaagtggtt gccacaacgc
    17641 atagtacaga ctatttgaca cgagaagtaa ctgttaaatt gagtgcagat actcataatg
    17701 tagatgtgat agaattagtg gggaattcat aatgagacag ttgaagcgag ttggagtatt
    17761 tttattgctt cctttctttg ttctaattga cgcccatatt agccagcttc tgggctcatt
    17821 tttcccccat gtacatttgg ctagtcattt tctttttcta tttctcttat ttgagacgat
    17881 agaagtatca gagtatctct acctagtcta ttgttttgtt ataggcttgg tttatgatgt
    17941 ttactttttc catctaatag ggattacaac tctcttattt atcttattgg gagccttcct
    18001 tcataaattg aatagtgtta ttttgttgaa tcgttggaca agaatgctag ctatgattgt
    18061 gctgacattc ctgtttgaaa tgggtagtta tcttttggct tttatggtag ggttgacagt
    18121 agatagcatg tcgattttta tagtctatag cttggtaccg acgatgattt taaatttttt
    18181 atggattact gtttttcaat ttatttttga aaaatattat ctataagaac gacatataaa
    18241 tgtaacaaag gcgtaatatt tattaggcct ttttttggta tactagtatt gtctttaaaa
    18301 gaaggagtat ctacgtaata tgaagaaaaa aatcttagcg tcacttttat taagtacagt
    18361 aatggtttct caagtagctg ttttaacaac tgcgcatgca gaaacgactg atgacaaaat
    18421 tgctgctcaa gataataaaa ttagtaactt aacagcacaa caacaagaag cccaaaaaca
    18481 agttgaccaa attcaggagc aagtatcagc tattcaagct gagcagtcta acttgcaagc
    18541 tgaaaatgat agattacaag cagaatctaa gaaactcgag ggtgagatta cagaactttc
    18601 taaaaacatt gtttctcgta accaatcgtt ggaaaaacaa gctcgtagtg ctcaaacaaa
    18661 tggagccgta actagctata tcaataccat tgtaaactca aaatcaatta cagaagctat
    18721 ttcacgtgtt gctgcaatga gtgaaatcgt atctgcaaac aacaaaatgt tagaacaaca
    18781 aaaggcagat aaaaaagcta tttctgaaaa acaagtagca aataatgatg ctatcaatac
    18841 tgtaattgct aatcaacaaa aattggctga tgatgctcaa gcattgacta cgaaacaggc
    18901 agaactaaaa gctgctgaat taagtcttgc tgctgagaaa gcgacagctg aaggggaaaa
    18961 agcaagtcta ttagagcaaa aagcagcagc tgaggcagag gctcgtgcag ctgcggtagc
    19021 agaagcagct tataaagaaa aacgagctag ccaacaacaa tcagtacttg cttcagcaaa
    19081 cactaactta acagctcaag tgcaagcagt atctgaatct gcagcagcac ctgtccgtgc
    19141 aaaagttcgt ccaacataca gtacaaacgc ttcaagttat ccaattggag aatgtacatg
    19201 gggagtaaaa acattggcac cttgggctgg agactactgg ggtaatggag cacagtgggc
    19261 tacaagtgca gcagcagcag gtttccgtac aggttcaaca cctcaagttg gagcaattgc
    19321 atgttggaat gatggtggat atggtcacgt agcggttgtt acagctgttg aatcaacaac
    19381 acgtatccaa gtatcagaat caaattatgc aggtaatcgt acaattggaa atcaccgtgg
    19441 atggttcaat ccaacaacaa cttctgaagg ttttgttaca tatatttatg cagattaatt
    19501 tacagaggga ctcgaataga gccctctttt caggttttac cgtgacaatc cctattaaaa
    19561 attatatcaa aatagcttga aaatattgga aaagtatggt agaatgaaaa ttgtcgtgtg
    19621 aacgataata ctcattcttg atgaattgtg aagcagttgc ccttgggtcg ttttgcgagt
    19681 tgaagtcaag aagaggaaaa aaacaaaaag gagaaatact catggcagta atttcaatga
    19741 aacaacttct tgaggctggt gtacactttg gtcaccaaac tcgtcgctgg aatcctaaga
    19801 tggctaagta catctttact gaacgtaacg gaatccacgt tatcgacttg caacaaactg
    19861 taaaatacgc tgaccaagca tacgacttca tgcgtgatgc agcagctaac gatgcagttg
    19921 tattgttcgt tggtactaag aaacaagcag ctgatgcagt tgctgaagaa gcagtacgtt
    19981 caggtcaata cttcatcaac caccgttggt tgggtggaac tcttacaaac tggggaacaa
    20041 tccaaaaacg tatcgctcgt ttgaaagaaa ttaaacgtat ggaagaagat ggaactttcg
    20101 aagttcttcc taagaaagaa gttgcacttc ttaacaaaca acgtgcgcgt cttgaaaaat
    20161 tcttgggcgg tatcgaagat atgcctcgta tcccagatgt gatgtacgta gttgacccac
    20221 ataaagagca aatcgctgtt aaagaagcta aaaaattggg aatcccagtt gtagcgatgg
    20281 ttgacaccaa tactgatcca gatgatatcg atgtaatcat cccagctaac gatgacgcta
    20341 tccgtgctgt taaattgatc acagctaaat tggctgacgc tattatcgaa ggacgtcaag
    20401 gtgaggatgc agtagcagtt gaagcagaat ttgcagcttc agaaactcaa gcagattcaa
    20461 ttgaagaaat cgttgaagtt gtagaaggtg acaacgctta atttatacaa atagtaatta
    20521 cctaggaggg cggggcttag cccggctctc ctattttcaa aaaatatagg agaattaaaa
    20581 tggcagaaat tacagctaaa cttgtaaaag agttgcgtga aaaatctggt gccggtgtta
    20641 tggacgctaa aaaagcgctt gtagaaacag acggtgacat cgaaaaagcg attgaattgc
    20701 ttcgtgaaaa aggtatggct aaggcagcta agaaagctga ccgtgttgct gcagaaggtt
    20761 tgactggtgt ttatgttaac ggtaatgttg cagcagttat tgaagtaaac gctgaaactg
    20821 acttcgttgc aaaaaacgct caattcgttg aattggtaaa tactacagct aaagtcattg
    20881 ctgaaggaaa acctgctaac aatgaagaag ctcttgcttt gataatgcct tcaggtgaaa
    20941 ctcttgaagc tgcatacgta tctgcaacag caactatcgg agagaaaatc tcattccgtc
    21001 gctttgcatt gattgaaaaa acagacgcac aacactttgg agcataccaa cataacggtg
    21061 gacgtatcgg tgttatttca gttgttgaag gtggagacga agcacttgct aaacaattgt
    21121 caatgcacat cgcagcgatg aaaccaacag ttctttctta caaagaattg gatgagcaat
    21181 tcgttaaaga tgagttggca caattgaatc acgttatcga ccaagacaac gaaagccgtg
    21241 caatggttaa taaaccagct cttccacact tgaagtatgg atcaaaagct caattaactg
    21301 atgatgttat tgctcaagct gaagctgaca tcaaagctga attggctgca gaaggcaaac
    21361 cagaaaaaat ctgggacaaa attattccag gtaaaatgga tcgcttcatg cttgataaca
    21421 ctaaagttga ccaagcttac acacttcttg cacaagttta catcatggat gacagcaaga
    21481 cagttgaagc ataccttgaa tcagttaacg cttcggtagt tgagtttgct cgctttgaag
    21541 ttggtgaagg tatcgagaaa gctgcaaacg acttcgaagc tgaagttgca gctacaatgg
    21601 cagcagcctt gaataactaa taatagaaag gaagcaaatt gcttcctttt ttgtataggg
    21661 cttagatttt tcctgaaatt gttttttccc cagtctcact cgattagaat aattaaaaca
    21721 aaaagcccta taataagggc taagggcatt taggagacta tacttcaaat tcatagtaag
    21781 cgcgttcata acaaggtatc tatcctaatt ccccaacttc cagtatacta gataaaaaat
    21841 aattatcgga ggaaaggtat tgtactatga taattcaact aagtgattta ggtcaagttc
    21901 accttgtttg tagcaagata gatatgaggc agggaataga ctcattagcc tatgtagtta
    21961 aaacccactt tgaattggat cctttctccg gtcaagtctt tctcttttgt ggtggacgta
    22021 aagaccgctt taaagccctt tactgggatg gtcaaggatt ttggctacta tataaacgct
    22081 ttgagaacgt cagactgact tggcccagta cagaaaagga tgtcaaagct ctcacacctg
    22141 aacaagtaga ctggcttatg aagggctttt ctatcactcc aaaaataaat ccatcagaaa
    22201 gtcgtgattt ctattgaaat gaggactttc tttttatact catctgcttt caaaaagcat
    22261 tctagtccat ctccgattaa cgatggactt tatcacctcc ttctccagtc cttgtataac
    22321 atcttggagt tgattcatga catcttccaa agtttaaaag gctttattct taaatccacg
    22381 tttacgaatc tctttccaca cttgttcaat ggggttcatc tctggtgtgt atggaggaat
    22441 aaatgcaaag ccaatattag tcggaatctt taaggtactt gatttatgcc atatagcatt
    22501 gtccataacg agtaaaagat aatcatctgg ataagcttgt gaaatctcct attcctaaag
    22561 cccctttagc gcataacttt ggctcagctt ctattatcgc tcacaccatc catcagaagt
    22621 ttaatctgaa ggtacccaat tatcgccaag aagaagattg ggctaggatg ggtttaccaa
    22681 tcacacgtaa ggaaatctct aatcggcata tcaagacgag tcaatactat ttggagcccc
    22741 tttataacct cttgcgagag agactattga ctcagccctt acttcatgcg gatgaaactt
    22801 cttatagggt gctagagagt gatagtcagc tgacttacta ttggactttt ttgtctggga
    22861 aagctgagaa acaagggatt acgctttacc atcatgtcct aatcgatttg ttcatatctt
    22921 atttcaatcc attataaata gtgagaaata tctatcctat cttctagaat gtcttccaaa
    22981 cgtggaaact ctcgtaaaca aagaggtttt agaggcctat ttaccatgga ctaaagttgt
    23041 acaagaaaag tgcaaataag aaatctccag attaggaact atccgtgagt tctctagtct
    23101 ggagattttt caatagactt cgttattgga cggttacaat tcataaagtg ctgtagagag
    23161 ataacgttca ccgttatctg gtgctagggc aaggactttt ttacctgtac ctaatttttt
    23221 ggcaacctcg atggctccgt agatagctgc agctgaggaa atccctacaa ggaagccttc
    23281 ttttccacca atttcacgtc cgagtgcaag agcgtcatct gatgttacac gaacgatacc
    23341 atcataggct ttagtatcaa gtgtatcagg aataaatcca gctgagatac cttgaatttt
    23401 gtgaggacca ggtttttcac cagatagaat agcagattca tctgcttcta ctgcaaaaac
    23461 ttgaatgtta gaattttctg atttgagtgc atgagaaaca ccagaaatcg ttccaccggt
    23521 acctactcca gcaacaaagg catctaatcc atctttaccg aaagcagcta gtatctcagc
    23581 tcctgttgtt ctttcgtgta cttctggatt agctggattg tcaaattgaa gaggaaggaa
    23641 accatcacgt tcagcagcga tttcttgagc cttagcaata gcacctttca ttccctcgct
    23701 accaggagtt aggacgagtt cagcaccata agcttggata attttacgtc gttctacact
    23761 catagtttca ggcataacga tgacgacttt atacccttta gcagcaccta cccatgaaag
    23821 tccaatacca gtgtttccac ttgttgcttc aacaatagta gaaccaggtt tcagaatacc
    23881 atcttgttca gctttttcaa tcatgctaag ggcaatacgg tcttttacag atgaaccagg
    23941 attaaatgct tcaagcttta tatagacgtc tgcagcacct tctggcacga tgttgttaag
    24001 tttaacaatc ggtgtttgac cgattaattc agtaatgttg ttataaatag acatatgaat
    24061 acctctttgt ataagatatc tttagtataa cgctatccat accatttgta aaatatagaa
    24121 atcctatcga agcgatagga tttctatata tcatagatca aagtcattaa ttttcaagtg
    24181 attgcgttca gctaattcta gtaaataggt gtgaaggaaa acgatatcag gtttcgtttg
    24241 aattgcttca ttttctagta tattttggta cgcatctttt tattttgctc gctaaagtag
    24301 ttgtgagaat gtcaacgaaa cgctgtatta ttcattgttt acactaagtt tacaggaact
    24361 tcaacctctc gtaaaccttg gtcagttaaa gtgacttttc cattaaaaaa ctccacaagt
    24421 gcagctttaa tagtttcttt ttcttcttta tcaacataaa tcatcgtatc gacttgatct
    24481 gtaaagtttg tatccagctc catgagatca tgttctttaa ggaagttact gtactcttgg
    24541 tactgagcat aagacatttg aatagcaatg ccagcctgtt cttttatttc aataatacca
    24601 atttctttga cagctaaggc gacactgccg gcgtaagcac gaattagtcc tccagcgcct
    24661 agtttaatac caccaaagta gcgtgtcacg accacacaga cattggtgag attgtgattt
    24721 tctagtaccc caagcatggg aacaccagca gtaccactag gctcaccatc atcacttgta
    24781 cgtttaattt cactacgttc tccaataata aaggcagagc agttatgtgt cgctttgtag
    24841 tgttcttttt tgatggcagt aatgaagtca cgagcctctt cttcgctata aacacgcttg
    24901 gcatggcaga taaagcgaga ttttttgatt tcttcttgga cttggtcgtc ctctttaatt
    24961 gttctaaatt ccatgattta attgtactaa aaaatcatct aaagtgctag tttttacgaa
    25021 taaagaagta tgaaagtaaa tttagattat ctcggtcgtt tatttactga gaatgaatta
    25081 acagaagaag aacgtcagtt ggcggagaaa cttccagcaa tgagaaagga gaaggggaaa
    25141 cttttctgtc aacgttgtaa tagtactatt ctagaagaat ggtatttgcc catcggtgct
    25201 tactattgtc gagagtgctt gctgatgaag cgagtcagaa gtgatcaaac tttatactat
    25261 tttccgcagg aggattttcc gaagcaagat gttctcaaat ggcgcggcca attaactcct
    25321 tttcaagaga aggtgtcaga gggactgctt caagcagtag acaagcaaaa gccaacctta
    25381 gttcatgcgg taacaggagc tggaaagaca gaaatgattt atcaagtagt ggctaaagtg
    25441 atcaatgcgg gtggtgcagt gtgtttggct agtcctcgca tagatgtttg tttggagctg
    25501 tacaagcgcc tgcaacagga tttttcttgc gggatagctt tgctacatgg agaatcggaa
    25561 ccttattttc gaacaccact agttgttgca acaacccatc agttattgaa gttttatcaa
    25621 gcttttgatt tgctgatagt ggatgaagta gatgcttttc cttatgttga taatccaatg
    25681 ctttaccacg ctgtcaagaa tagtgtaaag gagaatggat tgagaatctt tttaacagcg
    25741 acttcgacca atgagttaga taaaaaggtc cgtttaggag aactaaaaag actgaattta
    25801 ccgagacggt ttcatggaaa tccgttgatt attccaaaac caatttggtt atcggatttt
    25861 aatcgctact tagacaagaa tcgtttgtca ccaaagttaa agtcctatat tgagaagcag
    25921 agaaagacag cttatccgtt actcattttt gcttcagaaa ttaagaaagg ggagcagtta
    25981 gaagaaatct tacaggagca atttccaaat gagaaaattg gctttgtatc ttctgtaaca
    26041 gaggatcgat tagagcaagt acaagctttt cgagatggag aactgacaat acttatcagt
    26101 acgacaatct tggagcgtgg agttaccttc ccttgtgtgg atgttttcgt agtagaggcc
    26161 aatcatcgtt tgtttaccaa gtctagtttg attcagattg gtggacgagt tggacgaagc
    26221 atggatagac cgacaggaga tttgcttttc ttccatgatg ggttaaatgc ttcaatcaag
    26281 aaggcgatta aggaaattca gatgatgaat aaggaggctg gtctatgaag tgcttgttat
    26341 gtgggcagac tatgaagact gttttaactt ttagtagtct cttacttctg aggaatgatg
    26401 actcttgtct ttgttcagac tgtgattcta cttttgaaag aattggggaa gagaactgtc
    26461 caaattgtat gaaaacagag ttgtcaacaa agtgtcaaga ttgtcaattt tggtgtaaag
    26521 aaggagttgg agtcagtcat agagcgattt ttacttacaa tcaagctatg aaggattttt
    26581 tcagtcggta taagtttgat ggagacttcc tgttaagaaa agttttcgct tcatttttaa
    26641 gtgaggagtt gaaaaagtac aaagagtatc aatttgttgt aattccccta agtcctgata
    26701 gatatgctaa tagaggattt aatcaggttg agggcttggt agaggcagca ggttttgagt
    26761 atctggattt attagagaaa agagaagaga gagccagttc ttctaaaaat cgttcagagc
    26821 gcttggggac agaacttcct ttctttatta aaagtggagt cactattcct aaaaaaatcc
    26881 tacttataga tgatatctat actacaggag caactataaa tcgtgttaag aaactgttgg
    26941 aagaagctgg tgctaaggat gtaaaaacat tttcccttgt aagatgagga aaaaatttgc
    27001 aaaaatagaa tgaaagcgtt ataataaaat cataaaaaca aaaatgttta gaaagaaggt
    27061 actcatatga ttaaatatag tatccgtggt gaaaacctag aagtaacaga agcaattcgt
    27121 gattatgtag tttctaaact cgaaaagatc gaaaagtact tccaaccaga acaagagttg
    27181 gatgcccgaa ttaacttaaa agtttatcgt gaaaaaacgg ctaaagtgga agtaacgatt
    27241 ccgcttggat ctattactct ccgcgcagaa gatgtatctc aagatatgta tggttcaatt
    27301 gaccttgtaa ctgataaaat tgaacgtcag attcgtaaaa ataaaacaaa aatcgagcgt
    27361 aaaaataaaa ataaggtagc aactggtcaa ttatttacag atgctttggt ggaagattca
    27421 aatgttgtcc agtctaaagt tgttcgttca aaacaaattg atttaaaacc aatggatttg
    27481 gaagaagcaa ttctacaaat ggatttattg gggcatgatt tctttatcta tgtggatgtt
    27541 gaagatcaga caaccaatgt gatttatcgt cgtgaggatg gcgaaattgg tttgttagag
    27601 gttaaagaat cttaatttca atatgtgtaa aggtaggttt actgaattgt aaactacctt
    27661 tttcttataa ttgatagaat tactgattac acttttaaaa agtcgctttt tgaggggtat
    27721 tatggtataa tgggtgccaa gaggttttga atgaaaaaat tttatgtaag tccaattttt
    27781 cctattctag taggattgat tgcgtttgga gtcttatcca ctttcattat ttttgttaat
    27841 aataatctgt tgacggtttt aattttgttt ctttttgtag gaggctatgt ttttttattt
    27901 aagaaactga gagtgcatta tacaaggagt gatgtagaac agatacagta tgtaaaccac
    27961 caagcggaag aaagtttgac atctctattg gaacagatgc ctgtaggtgt tatgaaattg
    28021 aatttatctt ctggagaggt tgagtggttt aatccctatg ctgaattgat tttgaccaag
    28081 gaagatggtg attttgattt agaagctgtt caaacgatta ttaaggcttc agtaggaaat
    28141 ccgtctactt atgccaagct tggtgagaag cgttatgctg ttcatatgga tgcttcttcc
    28201 ggtgttttgt attttgtaga tgtatccagg gaacaagcca taacagatga attggtaaca
    28261 agtcgaccag tgattgggat tgtctctgtg gataattatg atgatttgga ggatgcaact
    28321 tctgagtcag atattagtca aatcaatagt tttgtagcta attttatatc agagttttca
    28381 gaaaaataca tgatgttttc tcgtcgggta agtatggatc gattttatct atttactgac
    28441 tacacggtgc ttgagggctt gatgaatgat aaattttctg ttattgatgc tttcagagaa
    28501 gagtcgaaac agagacagtt gcccttgacc ttaagtatgg gattttctta tggcgatgga
    28561 aatcatgatg agatagggaa agttgctttg ctcaatttga acttggctga agtacgtggt
    28621 ggcgaccagg tggttgttaa ggaaaacgac gaaacgaaaa atccagttta ttttggtggt
    28681 gggtctgctg cttcaatcaa gcgtacacgg actcgtacgc gcgctatgat gacagctatt
    28741 tcagataaga ttcggagtgt agatcaggtt tttgtagtcg gtcacaaaaa tttagacatg
    28801 gatgctttgg gctctgctgt aggtatgcag ttgttcgcca gcaatgtgat tgaaaatagc
    28861 tatgctcttt atgatgaaga acaaatgtct ccagatattg aacgagctgt ttcattcata
    28921 gaaaaagaag gagttacgaa gttgttgtct gttaaggatg caatggggat ggtgaccaat
    28981 cgttctttgt tgattcttgt agaccattca aagacagcct taacattatc aaaagaattt
    29041 tatgatttat ttacccaaac cattgttatt gaccaccata gaagggatca ggattttcca
    29101 gataatgcgg tcattactta tatcgaaagt ggtgcaagta gtgccagtga gttggtaacg
    29161 gaattgattc agttccagaa ttctaagaaa aatcgtttga gtcgtatgca agcaagtgtt
    29221 ttgatggctg gtatgatgtt ggatactaaa aatttcacct cgcgagtaac tagtcggaca
    29281 tttgatgttg ctagctatct cagaacgcgc ggaagtgata gtattgctat ccaggaaatc
    29341 gctgcgacag attttgaaga atatcgtgag gtcaatgaac ttattttaca ggggcgtaaa
    29401 ttaggttcag atgtactaat agcagaggct aaggacacga aatgctatga tacagttgtt
    29461 attagtaagg cagcagatgc catgttagcc atgtcaggta ttgaagcgag ttttgttctt
    29521 gcgaagaata cacaaggatt tatctctatc tcagctcgaa gtcgtagtaa actgaatgta
    29581 caacggatta tggaagagtt aggcggtgga ggccacttta atttggcagc agctcaaatt
    29641 aaagatgtaa ccttgtcaga agcaggtgaa aaactgacag aaattgtatt aaatgaaata
    29701 aaggaaaagg agaaagaaga atgaaagtaa tctttttagc agatgttaaa ggaaaaggta
    29761 aaaaaggcga aattaaggaa gtaccaacag ggtatgcgca aaactttctt atcaaaaaga
    29821 atctagccaa agaagcgact gctcaagctg taggtgaact tcgtggtaaa caaaaatcgg
    29881 aagaaaaagc tcacgctgag atgattgcag aaggaaaagc aattaaagca caacttgaag
    29941 cagaagaaac tgttgtagaa tttgttgaaa aagttggtcc agatggtcgt acctttggtt
    30001 ctattaccaa taagaagatt gcagaagaat tgcaaaagca atttggaatt aagattgata
    30061 aacgtcatat tcaagtacaa gctccgattc gagcggttgg tttgattgat gtgccagtga
    30121 aaatctatca agatatcaca agtgtaatca atcttcgtgt gaaagaagga taagtttaca
    30181 ccttcttgac aagattgtaa aaggaaggga agtctgatgg cagaagtaga agagttacga
    30241 gtacaacctc aagatatctt agctgagcaa tccgttttag gggctatctt tattgatgag
    30301 agtaaacttg tttttgtgcg agaatacatt gagtctcggg acttttttaa gtatgcccat
    30361 cgtttgattt tccaagccat ggtcgattta tccgatcgtg gtgatgccat agatgcaaca
    30421 acggttcgta ctatccttga taatcaaggt gatttacaga atattggtgg cttgtcttac
    30481 ttggttgaga ttgtcaattc tgtgccaact tctgctaatg cggagtatta tgctaagatt
    30541 gttgcagaaa aagcaatgct acgtcgttta attgccaagt tgacagagtc tgtcaaccaa
    30601 gcttacgaag cgtcacaacc agctgatgaa attattgctc aggcagaaaa agggctgatt
    30661 gatgtcagtg aaaatgcaaa tcgaagcggg tttaagaaca ttcgagatgt gttgaatctc
    30721 aactttggaa atctggaagc tcgctcgcaa caaacgaccg atattacagg tattgcgaca
    30781 ggttatcgtg atttggatca tatgacaaca ggacttcatg aggaggagtt gattatctta
    30841 gcagctcgtc cagcagttgg taagacagca tttgccttga atatcgctca gaacattggg
    30901 actaagttgg acaaaacggt tgctattttt tcactcgaaa tgggtgcgga aagcttggta
    30961 gatcgtatgt tagctgcaga aggcttagtg gagtcacatt ctatccgtac agggcaattg
    31021 acagatgagg agtggcaaaa atatactatt gctcagggta atctagctaa cgccagtatc
    31081 tatatcgatg atacgccagg tattcggatt acagagattc gttctcgttc tcgtaaattg
    31141 gctcaagaaa ctggaaatct tggtttgatt ttgatagact atttgcaact tatcacggga
    31201 actggtcgag aaaatcgtca acaagaagtt tctgaaattt ctcgtcagtt gaaaatacta
    31261 gccaaggaat tgaaggttcc agtaatcgct ctgagtcagc tttctcgtgg tgtagaacaa
    31321 cgtcaggaca agagaccggt cttgtctgat attcgtgaat ctgggtctat tgagcaggac
    31381 gctgatatcg tagcttttct ctatcgcgat gactactatg aacgtggtgg tgaagaagag
    31441 gagggtatcc caaataataa ggtggaagtt attatcgaga aaaaccgtag tggagctcgt
    31501 ggaacagtgg aattgatttt ccaaaaagaa tacaataaat tttcaagtat ctcaaagagg
    31561 gaggcataag atgtcagatg catttacaga tgtagccaag atgaaaaaaa tcaaagaaga
    31621 aatcaaggca catgagggac aagtcgtaga aatgactttg gagaatggtc gtaagcgcca
    31681 aaaaaataga ttgggtaagc taattgaagt ttatccatcc ctatttattg tggagtttgg
    31741 ggatgtggaa ggagataaac aagttaatgt ttacgttgaa tcctttactt actcagatat
    31801 tcttacagaa aagaatttga ttcattatct tgactaaagt gagaaatttt ctcacttttt
    31861 cttttttctc cgaataattt aggtgaaggc aatcatcgct ttatattatt tttcaaggag
    31921 gaagaatgaa aattttaccg tttatagcaa gaggaacaag ttattacttg aagatgtcag
    31981 ttaaaaagct tgttcctttt ttagtagtag gattgatgct agcagctggt gatagtgtct
    32041 atgcctattc cagaggaaat ggatcgattg cgcgtgggga tgattatcct gcttattata
    32101 aaaatgggag ccaggagatt gatcagtggc gcatgtattc tcgtcagtgt acttcttttg
    32161 tagcctttcg tttgagtaat gtcaatggtt ttgaaatgcc ggcagcttat ggaaatgcga
    32221 atgaatgggg acatcgtgct cgtcgggaag gttatcgtgt agataataca ccgacgattg
    32281 gttccattac ttggtctact gcaggaactt atggtcatgt tgcctgggtg tcaaatgtaa
    32341 tgggagatca gattgagatt gaggaatata actatggtta tacagaatcc tataataaac
    32401 gagttataaa agcaaacacg atgacaggat ttattcattt taaagatttg gatggcggca
    32461 gcgttgggaa tagtcaatcc tcagcttcaa caggcggaac tcattatttt aagaccaagt
    32521 ctgctattaa acctgaaccc ctagctagcg gaactgtgat tgattactat tatcctgggg
    32581 agaaggttca ttatgatcag atatttgaaa aagacggcta taagtggttg agttatactg
    32641 cctataatgg aagctatcgt tatgttcaat tggaggctgt gaataaaaat cctctaggta
    32701 attctgttct ttcttcaaca ggcggaactc attattttaa gaccaagtct gctatcaaaa
    32761 ctgaacccct agttagtgca actgtgattg attactatta tcctggagag aacgttcatt
    32821 atgatcaaat tctcgaaaaa gacggctaca agtggttgag ttatacggct tataacggaa
    32881 gtcgtcgcta tatacagcta gagggagtga cttcttcaca aaattatcag aatcaatcag
    32941 gaaacatctc tagctatgga tcccatagta gttcaactgt cggttggaag aaaataaatg
    33001 gtagttggta tcatttcaaa tcaaatggtt ctaaatcaac aggatggctg aaagacggtt
    33061 ctagctggta ttatttgaaa ttatctggtg aaatgcagac aggatggtta aaggaaaatg
    33121 gtttgtggta ttatctgggt agttcagggg caatgaaaac aggctggtac caggtctctg
    33181 gtaagtggta ttattcttac tcttcaggcg ccttagctgt taatacgacg gtggatggct
    33241 acagagtaaa cagtgatgga gaacgagtat agaaaattgg agtaggagaa atttcctgct
    33301 cttttctgta agcagtttcc ttgacatttt tcttattttg cgctatcata tatacatata
    33361 atatatggga gtctgtgtac agtctgagag gaagtgttaa acttcgaccg cacctgatct
    33421 gggtaatgcc agcggaggga acgatactta gtctaatttt gcaccttttc catgtatggt
    33481 aaaggttttt ctttttttaa aaaggaaaac gagaagagga ggttcttatg aaagcaagca
    33541 ttgccttgca agttttaccc ctagtacagg ggattgatcg gatagctgtt attgatcagg
    33601 tcattgctta tctgcaaact caagaagtga cgatggtagt gacaccattt gaaacggtct
    33661 tggaagggga gtttgatgag cttatgcgca ttctaaaaga agcgctggaa gtggcagggc
    33721 aggaggcaga caatgtcttt gccaatgtca aaataaatgt aggagagatt ttaagtattg
    33781 atgagaaact tgagaagtat actgagacga cacattagtc tattgggctt tctcggagta
    33841 ttgtcaatct ggcagttagc aggttttctt aaacttctcc ccaagtttat cctgccgaca
    33901 cctcttgaaa ttctccagcc ctttgttcgt gacagagaat ttctctggca ccatagctgg
    33961 gcgaccttga gagtggcttt actggggctg attttgggag ttttgattgc ctgtcttatg
    34021 gctgtgctca tggatagttt gacttggctc aatgacctga tttaccctat gatggtggtc
    34081 attcagacca ttccgaccat tgccatagct cctatcctgg tcttgtggct aggttatggg
    34141 attttgccca agattgtctt gattatctta acgacaacct ttcccatcat cgttagtatt
    34201 ttggacggtt ttaggcattg cgacaaggat atgctgacct tgtttagtct gatgcgggcc
    34261 aagccttggc aaatcctgtg gcattttaaa atcccagtta gcctgcctta cttttatgca
    34321 ggtctgaggg tcagtgtctc ctacgccttt atcacaactg tggtatctga gtggttggga
    34381 ggttttgaag gtcttggtgt ttatatgatt cagtctaaaa aactgtttca gtatgatacc
    34441 atgtttgcca ttattattct ggtgtcgatt atcagtcttt tgggtatgaa gctggtcgat
    34501 atcagtgaaa aatatgtgat taaatggaaa cgttcgtaga attagaatgt ttctgaaaaa
    34561 gaaaagagga aatcaaaatg aagaaaacat ggaaagtgtt tttaacgctt gtaacagctc
    34621 ttgtagctgt tgtgcttgtg gcctgtggtc aaggaactgc ttctaaagac aacaaagagg
    34681 cagaacttaa gaaggttgac tttatcctag actggacacc aaataccaac cacacagggc
    34741 tttatgttgc caaggaaaaa ggttatttca aagaagctgg agtggatgtt gatttgaaat
    34801 tgccaccaga agaaagttct tctgacttgg ttatcaacgg aaaggcacca tttgcagtgt
    34861 atttccaaga ctacatggct aagaaattgg aaaaaggagc aggaatcact gccgttgcag
    34921 ctattgttga acacaataca tcaggaatca tctctcgtaa atctgataat gtaagcagtc
    34981 caaaagactt ggttggtaag aaatatggga catggaatga cccaactgaa cttgctatgt
    35041 tgaaaacctt ggtagaatct caaggtggag actttgagaa ggttgaaaaa gtaccaaata
    35101 acgactcaaa ctcaatcaca ccgattgcca atggcgtctt tgatactgct tggatttact
    35161 acggttggga tggcatcctt gctaaatctc aaggtgtaga tgctaacttc atgtacttga
    35221 aagactatgt caaggagttt gactactatt caccagttat catcgcaaac aacgactatc
    35281 tgaaagataa caaagaagaa gctcgcaaag tcatccaagc catcaaaaaa ggctaccaat
    35341 atgccatgga acatccagaa gaagctgcag atattctcat caagaatgca cctgaactca
    35401 aggaaaaacg tgactttgtc atcgaatctc aaaaatactt gtcaaaagaa tacgcaagcg
    35461 acaaggaaaa atggggtcaa tttgacgcag ctcgctggaa tgctttctac aaatgggata
    35521 aagaaaatgg tatccttaaa gaagacttga cagacaaagg cttcaccaac gaatttgtga
    35581 aataatgaca gaaattagac tagagcacgt cagttatgcc tatggtcagg agaggatttt
    35641 agaggatatc aacctacagg tgacttcagg cgaagtggtt tccatcctag gcccaagtgg
    35701 tgttggaaag accaccctct ttaatctaat cgctgggatt ttagaagttc agtcagggag
    35761 aattgtcctt gatggtgaag aaaatcccaa ggggcgcgtg agttatatgt tgcaaaagga
    35821 tctgctcttg gagcacaaga cggtgcttgg aaatatcatt ctgcccctct tgattcaaaa
    35881 ggtggataag gcagaagcta tttcccgagc ggataaaatt cttgcgacct tccagctgac
    35941 agctgtaaga gacaagtatc ctcatgaact tagcggtggg atgcgccagc gtgtagcctt
    36001 actccggacc tacctttttg ggcacaagct ctttctctta gatgaggcct ttagcgcctt
    36061 ggatgagatg acaaagatgg aactccacgc ttggtatctt gagattcaca aacagttgca
    36121 gctaacaact ctgatcatca cgcatagtat tgaggaggcc ctcaatctca gcgaccgcat
    36181 ctatatcttg aaaaatcgcc ctgggcagat tgtttcagaa attaaactag attggtctga
    36241 agatgaggac aaggaagtcc aaaagattgc ctacaaacgt caaatcttgg cagaattagg
    36301 cttagataag tagaaaaata gggagttggt gaagattatc ctttaccagc gccctttttc
    36361 ttttaaaaat gagaaaattt cggtataata gtcaaacaag gtcaaggttt aaagagagag
    36421 gtgggtttgt tatgagattt aaaaatacat cggatcatat tgaggcctac atcaaggcga
    36481 ttttagatca atctggtatc gtggagttgc aacggagtca gttggcagat acctttcagg
    36541 ttgttcctag tcagattaac tacgtgatca agacacgctt tacggaaagt agaggctact
    36601 tggttgaaag taagcgtggt ggcggaggct acattcgtat aggacggatt gagttttcta
    36661 gtcatcatga aatgctccgg gatctgcttt actcgattgg tgagcgagtc agtcaagaaa
    36721 tttatgagga tattctccag cttttggttg agcaggaatt gatgaccaag caggagatga
    36781 atttgctaga atcagtagct ttggatcgcg ttttaggaga agaagctcca gttgttcgag
    36841 caaacatgct acgtcaggtc atacaagagg tagatagaaa agggaagtaa gatgaactat
    36901 tcaaaagcat tgaatgaatg tatcgaaagt gcctacatgg ttgctggaca ttttggagct
    36961 cgttatctag agtcgtggca cttgttgatt gccatgtcta atcacagtta tagtgtagca
    37021 ggggcaactt taaatgatta tccgtatgag atggaccgtt tagaagaggt ggctttggaa
    37081 ctgactgaaa cggactatag ccaggatgaa acctttacgg aattgccgtt ctcccgtcgt
    37141 ttgcaggttc tttttgatga agcagagtat gtagcgtcag tggtccatgc taaggtacta
    37201 gggacagagc acgtcctcta tgcgattttg catgatggca atgccttggc gactcgtatc
    37261 ttggagaggg ctggtttttc ttatgaagac aagaaagatc aggtcaagat tgctgccctt
    37321 cgtcgaaatt tagaagaacg tgcaggctgg actcgtgaag atctcaaggc tttacgccaa
    37381 cgccatcgta cagtagctga caagcaaaat tctatggcca atatgatggg catgccgcag
    37441 actcctagtg gtggtctcga ggactatacg catgatttga cagagcaagc gcgttctggc
    37501 aagttagaac cagtcatcgg tcgggacaag gaaatctcac gtatgattca aatcttgagc
    37561 cgtaagacta agaacaaccc tgtcttggtt ggggatgctg gtgtcgggaa aacagctctg
    37621 gcccttggtc ttgcccagcg tattgctagt ggtgacgtgc ctgcggaaat ggctaagatg
    37681 cgcgtgttag aacttgattt gatgaatgtc gttgcaggga cacgcttccg tggtgacttt
    37741 gaagaacgca tgaataatat catcaaggat attgaagaag atggccaagt catcctcttt
    37801 atcgatgaac tccacaccat catgggttct ggtagcggaa ttgattcgac tctggatgcg
    37861 gccaatatct tgaaaccagc cttggcgcgt ggaactttga gaacggttgg tgccaccact
    37921 caggaagaat atcaaaaaca tatcgaaaaa gatgcggctc tttctcgtcg tttcgctaaa
    37981 gtgacgattg aagaaccaag tgtggcagat agtatgacta ttttacaagg tttgaaggcg
    38041 acttatgaga aacatcaccg tgtacaaatc acagatgaag cggttgaaac agcggttaag
    38101 atggctcatc gttatttaac cagtcgtcac ttgccagact ctgctatcga cctcttggac
    38161 gaagcagcag caacagtgca aaataaggca aagtatgtaa aagcagacga ttcagatttg
    38221 agtccagctg acaaggccct gatggatggc aagtggaaac aggcagccca gctaatcgca
    38281 aaagaagagg aagtacctgt ctacaaagac ttggtgacag agtctgatat tttgaccacc
    38341 ttgagtcgct tgtcaggaat cccagttcaa aaactgactc agactgacgc taagaaatat
    38401 ctaaatcttg aagcagaact ccataaacgg gttatcggtc aagatcaagc tgtttcaagt
    38461 attagtcgtg cgattcgccg taatcagtca ggaattcgca gtcacaagcg tccgatcggt
    38521 tcctttatgt tcctaggacc cacaggtgtc ggtaagaccg agttggccaa ggctttggca
    38581 gaagttctct ttgatgacga atcagccctt atccgctttg atatgagtga gtatatggag
    38641 aaattcgcag ccagccgtct aaatggagct cctccaggct atgtgggtta cgaagaaggt
    38701 ggggagttga cagagaaggt tcgcaataaa ccctattccg ttctcctctt tgatgaggta
    38761 gagaaggctc acccagatat ctttaatgtt ctcttgcagg ttctggatga cggtgtcttg
    38821 acagatagca agggacgcaa ggtcgatttt tcaaatacca ttatcattat gacatcgaac
    38881 ctaggtgcga ctgcccttcg tgatgataag actgttggtt ttggggctaa ggatattcgt
    38941 tttgaccagg aaaatatgga aaaacgcatg tttgaagaac tgaaaaaagc ttatagaccg
    39001 gaattcatca accgtattga tgagaaggtg gtcttccata gcctatctag tgaccatatg
    39061 caggaagtgg tgaagattat ggtcaagcct ttagtggcaa gcttggctga aaaaggcatt
    39121 gacttgaaat tacaagcttc agctctgaaa ttgttagcaa atcaaggata tgacccagag
    39181 atgggagctc gcccacttcg cagaaccctg caaacagaag tggaggacaa gttggcagaa
    39241 cttcttctta agggagattt agtggcaggc agcacactta agattggtgt caaagcaggc
    39301 cagttaaaat ttgatattgc ataaaagaat aaaagtatca gcatctgacc ataagtcaca
    39361 gtggagtgaa actcaatgaa aatcaaagaa caaactaggc agctagccgc aggttgctca
    39421 aaacactgtt ttgaggttgt agatagagct gacgtggttt ggagagattt tcgaagagta
    39481 taagctgcaa gatgaatgat tttcttgtat tgacgttgtt gttgacaaaa agtagcggat
    39541 aaatgaaatc cattctatta tcatagatga taggctggta ggaaattttc aaatagcata
    39601 caggaaatag atgtatggag ttctggtagt agaaagggag agagatgaac attttagttg
    39661 cagatgacga ggaaatgatt agagaaggaa ttgcagcatt tctgacagaa gagggttatc
    39721 atgtcattat ggctaaggat ggacaagagg tcttggaaaa atttcaagat ctccctatcc
    39781 atctcatggt attggattta atgatgccta ggaagagtgg ttttgaagtg ttaaaagaaa
    39841 tcaatcaaaa gcacgatatt cctgtcatcg tcttgagtgc tctgggagat gaaactactc
    39901 agtcacaggt atttgatctc tatgctgatg atcatgtgac aaaacctttt tctttggtac
    39961 tgcttgtcaa gcgtattaag gcgcttatca gacgttacta cgtcatagag gatatttggc
    40021 gatatcagga tgtaacagtg gattttacct cttacaaagc acattataaa aatgaagaaa
    40081 ttgatctcaa gccaaaggaa ttactggtac taaagtgttt gattcagcat aaaaatcaag
    40141 ttttaagtag agagcagata ttggaagaaa tttcaaaaga tgtagctgat ttaccttgtg
    40201 atagggtcgt tgatgtctat attcgtactc ttcgcaaaaa attagcttta gattgtatcg
    40261 tgactgtgaa aaatgttggg tataagatta gcttatgata aaaaatccta aattattaac
    40321 caagtctttt ttaagaagtt ttgcaattct aggtggtgtt ggtctagtca ttcatatagc
    40381 tatttatttg acctttcctt tttattatat tcaactggag ggggaaaagt ttaatgagag
    40441 cgcaagagtg tttacggagt atttaaagac taagacatct gatgaaattc caagcttact
    40501 ccagtcttat tcaaagtcct tgaccatatc tgctcacctt aaaagagata ttgtagataa
    40561 gcggctccct cttgtgcatg acttggatat taaagatgga aagctatcaa attatatcgt
    40621 gatgttagat atgtctgtta gtacagcaga tggtaaacag gtaaccgtgc aatttgttca
    40681 cggggtggat gtctacaaag aagcaaagaa tattttgctt ttgtatctcc catatacatt
    40741 tttggttaca attgcttttt cctttgtttt ttcttatttt tatactaaac gcttgctcaa
    40801 tcctcttttt tacatttcag aagtgactag taaaatgcaa gatttggatg acaatattcg
    40861 ttttgatgaa agtaggaaag atgaagttgg tgaagttggt gaagttggaa aacagattaa
    40921 tggtatgtat gagcacttgt tgaaggttat tcatgagttg gaaagtcgta atgagcaaat
    40981 tgtaaaattg caaaatcaaa aggtttcctt tgtccgcgga gcatcacatg agttgaaaac
    41041 ccctttagcc agtcttagaa ttatcctaga gaatatgcag cataatattg gagattacaa
    41101 agatcatcca aaatatattg caaagagtat aaataagatt gaccagatga gccacttatt
    41161 ggaagaagta ctggagtctt ctaaattcca agagtggaca gagtgtcgtg agaccttgac
    41221 tgttaagcca gttttagtag atattttatc acgttatcaa gaattagctc attcaatagg
    41281 tgttacaatt gaaaatcaat tgacagatgc taccagggtc gtcatgagtc ttagggcatt
    41341 ggataaggtt ttgacaaacc tgattagtaa tgcaattaaa tattcagata aaaatgggcg
    41401 cgtaatcata tccgagcaag atggctatct ctctatcaaa aatacatgtg cgcctctaag
    41461 tgaccaagaa ctagaacatt tatttgatat attctatcat tctcaaatcg tgacagataa
    41521 ggatgaaagt tccggtttgg gtctttacat tgtgaataat attttagaaa gctatcaaat
    41581 ggattatagt tttctccctt atgaacacgg tatggaattt aagattagct tgtagacaga
    41641 ttagtttttt attaaagttc atatagggtt aacataagtg tgttattctt tgtgtagata
    41701 aaagaaagga tactaatatg gtattagcga ttattttagt aacattcctt attcgattga
    41761 tttttttaaa gcgttcgata gagaatgaga aacgaatcct tagcaatggc gggaaagaat
    41821 ttggagttga gaatacaaaa cgattaacta tggctcatat tgttttttat ctctcttgct
    41881 tggttgaggc aatggtgcac aagacaattt ttgatggcat gggcatggtt ggtttagtct
    41941 tgcttatttt ttctatgctg atgttaatgt tggtgattca cttgttggga gatatttgga
    42001 cagtgaagct tatgcttgtc aataatcaca aatatgtaga tcatatcttg tttaggacag
    42061 taaaacatcc taattacttt ttaaatattc ttcctgagtt gattggcttg accttgttga
    42121 gtcatgctta tgtgactttt gttttagttt ttccagttta tgcagttatt ttgtatcgac
    42181 gaatagctga agaggaaaag ctattacatg aagttataat cccaaatgga agcataaaga
    42241 gataaataca aaattcgatt tatatacagt tcatattgaa gtgatatagt aaggttaaag
    42301 aaaaaatata gaaggaaata attatgtttg catcaaaaag cgaaagaaaa gtacattatt
    42361 caattcgtaa atttagtatt ggagtagcta gtgtagtagt tgccagcttg ttcttaggag
    42421 gagtagtcca tgcagaaggg gttagaagtg ggaataactc cacggttaca tctagtgggc
    42481 aagatatatc gaagaagtat gctgatgaag tcgagtcgca tctacaaagt atattgaagg
    42541 atgtcaataa aaatttgaaa aaagttcaac atacccaaaa tgccgacttc aacaaaaagt
    42601 tgagcaaaat taaaacgaag tatttgtatg aattaaatgt tttagaagag aagtcggaag
    42661 ctgagttgac gtcaaaaaca aaagaaacaa aagaagagtt aaccgcagct tttgagcagt
    42721 ttaaaaaaga tacattatca acagaaccag aaaaaaaggt agcagaagct aagaagaagg
    42781 ttgaagaagc taagaaaaaa gccgaggatc aaaaagaaaa agatcgccgt aactacccaa
    42841 ccattactta caaaacgctt gaacttgaaa ttgctgagtc cgatgtggaa gttaaaaaag
    42901 cggagcttga actagtaaaa gtgaaagcta acgaacctcg agacgaggaa aaaattaagc
    42961 aagcagaagc gaaagttgag agtaaacaag ctgaggctac aaggttaaaa aaaatcaaga
    43021 cagatcgtga acaagctgag gctacaaggt tagaaaacat caagacagat cgtgaacaag
    43081 cagaagaaga agctaaagtt aaagatgaac caaagaagcg gacaaaacga ggagttcttg
    43141 gagagccagc aacacctgat aaaaaagaaa atgatgcgaa gtcttcagat tctagcgtag
    43201 gtgaagaaac tcttccaagc ccatccctga aaccagaaaa aaaggttgca gaagctgaga
    43261 agaaggttga agaagctaag aaaaaagccg aggatcaaaa agaagaagat cgtcgtaact
    43321 acccaaccaa tacttacaaa acgcttgaac ttgaaattgc tgagtccgat gtggaagtta
    43381 aaaaagcgga gcttgaacta gtaaaagagg aagctaagga acctcgaaac gaggaaaaag
    43441 ttaagcaagc aaaagcggaa gttgagagta aacaagctga ggctacaagg ttagaaaaaa
    43501 tcaagacaga tcgtaaaaaa gcagaagaag aagctaaacg aaaagcagca gaagaagata
    43561 aagttaaaga aaaaccagct gaacaaccac aaccagcgcc ggctcctcaa ccagaaaaac
    43621 cagctccaaa accagaaaaa ccagctccag ctccaaaacc agagaatcca gctgaacaac
    43681 caaaagcaga aaaaccagct gatcaacaag ctgaagaaga ctatgctcgt agatcagaag
    43741 aagaatataa tcgcttgact caacagcaac cgccaaaaac tgaaaaacca gcacaaccat
    43801 ctactccaaa aacaggctgg aaacaagaaa acggtatgtg gtacttctac aatactgatg
    43861 gttcaatggc gacaggatgg ctccaaaaca atggctcatg gtactaccta aacagcaatg
    43921 gcgctatggc gacaggatgg ctccaaaaca atggttcatg gtactatcta aacgctaatg
    43981 gttcaatggc aacaggatgg ctccaaaaca atggttcatg gtactacctc aacgctaatg
    44041 gttcaatggc aacaggatgg ctccaaaaca atggttcatg gtactacctc aacgctaatg
    44101 gttcaatggc gacaggatgg ctccaataca atggttcatg gtactaccta aacgctaatg
    44161 gtgatatggc gacaggatgg ctccaataca atggctcatg gtactaccta aacgctaatg
    44221 gttcaatggt gacaggatgg ctccaataca atggttcatg gtactaccta aacgctaacg
    44281 gttcaatggc aacag
//
LOCUS       DBEJAU010000011        39738 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC323 isolate 683620
            SAMN38261939-rid24807223.denovo.011, whole genome shotgun sequence.
ACCESSION   DBEJAU010000011 DBEJAU010000000
VERSION     DBEJAU010000011.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261939
            Sequence Read Archive: SRR26833919
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 39738)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 39738)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576303.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576303.1
            Genome Coverage       :: 154x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/19/2025 01:05:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,121
            CDSs (total)                      :: 2,078
            Genes (coding)                    :: 1,943
            CDSs (with protein)               :: 1,943
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 36
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 72 of 135
            Pseudo Genes (incomplete)         :: 63 of 135
            Pseudo Genes (internal stop)      :: 51 of 135
            Pseudo Genes (multiple problems)  :: 46 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..39738
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261939-rid24807223.denovo.011"
                     /strain="GPSC323"
                     /isolate="683620"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            9..89
                     /locus_tag="ACL29Z_000656"
     tRNA            9..89
                     /locus_tag="ACL29Z_000656"
                     /product="tRNA-Tyr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:43..45,aa:Tyr,seq:gta)
     gene            94..164
                     /locus_tag="ACL29Z_000657"
     tRNA            94..164
                     /locus_tag="ACL29Z_000657"
                     /product="tRNA-Trp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:126..128,aa:Trp,seq:cca)
     gene            179..251
                     /locus_tag="ACL29Z_000658"
     tRNA            179..251
                     /locus_tag="ACL29Z_000658"
                     /product="tRNA-His"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:212..214,aa:His,seq:gtg)
     gene            265..336
                     /locus_tag="ACL29Z_000659"
     tRNA            265..336
                     /locus_tag="ACL29Z_000659"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:297..299,aa:Gln,seq:ttg)
     gene            346..429
                     /locus_tag="ACL29Z_000660"
     tRNA            346..429
                     /locus_tag="ACL29Z_000660"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:380..382,aa:Leu,seq:caa)
     gene            536..1813
                     /locus_tag="ACL29Z_000661"
     CDS             536..1813
                     /locus_tag="ACL29Z_000661"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001277926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gamma-glutamylcysteine synthetase"
                     /protein_id="HGR0069004.1"
                     /translation="MSCSIDLLKHRYLKNIKENPELFVGIELEYPVASLEGDATDVEV
                     IKDLFHYLVSTLDLTVAKVDDFSNLIQLVDPINQDAILFEVSYTTIEFAFGKAETIQE
                     VENRFNNYMNVIQRKLAESNHAIVGCGIHPNWDKNENCPVAYPRYQMLMDYLNLSRNI
                     IKSDLHHFPEYGTFICGSQVQLDISKTNYLRVINAFTQIEAAKAYLFANSEFSGADWD
                     TKISRDIFWEESMHGIYPENVGVNARLLNDEADFFDYLNHSAIFTAERDGQTYYFYPI
                     QAGDYLATPEIQAFALNGDEVIIYPQEKDFETHRSYQYQDLTTRGTVEFRSVCTQPLD
                     RTFASAAFHLGLLVNLDKLEAYLETAPFFKVFGYDYKSLRRQFSKKNLTDEEETTIIE
                     FSKDLLLLAEEGLVVRNKEEMTYLQPLREELSL"
     gene            1889..3373
                     /gene="thrC"
                     /locus_tag="ACL29Z_000662"
     CDS             1889..3373
                     /gene="thrC"
                     /locus_tag="ACL29Z_000662"
                     /EC_number="4.2.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006595200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004795 - threonine synthase activity
                     [Evidence IEA];
                     GO_process: GO:0009088 - threonine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="threonine synthase"
                     /protein_id="HGR0069005.1"
                     /translation="MTLVYQSTRDANNTVTASQAILQGLATDGGLFTPVTYPKVDLDF
                     DKLKDTSYQEVAKLVLSAFLDDFTAEELDYCINNAYDSKFDTPAIAPLVKLDGQYNLE
                     LFHGSTIAFKDMALSILPYFMTTAAKKHGLENKIVILTATSGDTGKAAMAGFADVPGT
                     EIIVFYPKDGVSKIQELQMTTQTGDNTHVIAIDGNFDDAQTNVKHMFNDVALREKLTT
                     NKLQFSSANSMNIGRLVPQIVYYVYAYAQLVKTGEIVAGEKVNFTVPTGNFGNILAAF
                     YAKQIGLPVGKLICASNDNNVLTDFFKTRVYDKKREFKVTTSPSMDILVSSNLERLIF
                     HLLGNNAEKTVELMNALNTQGQYKLTDFDAEILDLFAAEYATEEETAAEIKRVCELDS
                     YIEDPHTAVASAVYKKYQSATGDVTKTVIASTASPYKFPVVAVEAVTGKAGLTDFEAL
                     AQLHEISGVAVPPAVDGLEIAPIRHKTTVAAADMQAAVEAYLGL"
     gene            3434..4714
                     /locus_tag="ACL29Z_000663"
     CDS             3434..4714
                     /locus_tag="ACL29Z_000663"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000473957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HGR0069006.1"
                     /translation="MFKKNKDILNIALPAMGENFLQMLMGMVDSYLVAHLGLIAISGV
                     SVAGNIITIYQAIFIALGAAISSVISKSIGQKDQSKLAYHVTEALKITLLLSFLLGFL
                     SIFAGKEMIGLLGTERDVAESGGLYLSLVGGSIVLLGLMTSLGALIRATHNPRLPLYV
                     SFLSNALNILFSSLAIFVLDMGIAGVAWGTILSRLVGLVILWSQLKLPYGKPTFGLDK
                     ELLTLALPAAGERLMMRAGDVVIIALVVSFGTEAVAGNAIGEVLTQFNYMPAFGVATA
                     TVMLLARAVGEDDWKRVASLSKQTFWLSLFLMLPLSFSIYVLGVPLTHLYTTDSLAVE
                     ASVLVTLFSLLGTPMTTGTVIYTAVWQGLGNARLPFYATSIGMWCIRIGTGYLLGIVL
                     GWGLPGIWAGSLLDNGFRWLFLRYRYQRYMSLKG"
     gene            4718..5338
                     /locus_tag="ACL29Z_000664"
     CDS             4718..5338
                     /locus_tag="ACL29Z_000664"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001172828.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HGR0069007.1"
                     /translation="MQKTAFIWDLDGTLLDSYEAILSGIEETFAQFSIPYDKEKVREF
                     IFKYSVQDLLVRVAEDRNLDVEVLNQVRAQSLAEKNAQVVLMPGAREVLAWADESGIQ
                     QFIYTHKGNNAFTILKDLGVESYFTEILTSQSGFVRKPSPEAATYLLDKYQLNSDNTY
                     YIGDRTLDVEFAQNSGIQSINFLESTYEGNHRIQALADISRIFETK"
     gene            5504..6646
                     /locus_tag="ACL29Z_000665"
     CDS             5504..6646
                     /locus_tag="ACL29Z_000665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000746996.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HGR0069008.1"
                     /translation="MKKRMLLASTVALSFAPVLATQAEEVLWTARSVEQIQNDLTKTD
                     NKTSYTVQYGDTLSTIAEALGVDVTVLANLNKITNMDLIFPETVLTTTVNEAEEVTEV
                     EIQTPQADSSEEVTTATADLTTNQVTVDDQTVQVADLSQPIAEAPKEVASSSEVTKTV
                     IASEEVAPSTGTSVPEEQTAETSSAVAEEAPQETTPAEKQETQASPQAASAVEATTTS
                     SEAKEVASSNGATAAVSTYQPEETKVISTTYEAPAAPDYAGLAVAKSENAGLQPQTAA
                     FKEEIANLFGITSFSGYRPGDSGDHGKGLAIDFMVPERSELGDKIAEYAIQNMASRGI
                     SYIIWKQRFYAPFDSKYGPANTWNPMPDRGSVTENHYDHVHVSMNG"
     gene            6969..7394
                     /locus_tag="ACL29Z_000666"
     CDS             6969..7394
                     /locus_tag="ACL29Z_000666"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000890080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family winged helix-turn-helix
                     transcriptional regulator"
                     /protein_id="HGR0069009.1"
                     /translation="MLEIQDLLYQLRLSEQASTQLFEKRLGISLTRYQILLFLLEHSP
                     CNQMAIQERLKIDQAALTRHFKILETEGLVERHRNPENQREVLVEAAKYAKEQLVVNP
                     PLQHIKVKEEMESILTEFERTELSRLLNKLVLGIENIEI"
     gene            7405..7806
                     /locus_tag="ACL29Z_000667"
     CDS             7405..7806
                     /locus_tag="ACL29Z_000667"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000022864.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1304 domain-containing protein"
                     /protein_id="HGR0069010.1"
                     /translation="MSIITIILTTIVALEHFYIFYLESIATRSDATSRVFNMEKEELA
                     HPSVSSLFKNQGIYKALLGVFLWYGIYFSQNLEIVTIFVLFVIGAATYGSLTADKKII
                     LKQGGSAILALISILLFKIHLKVDSNLANPF"
     gene            7881..8525
                     /gene="pcp"
                     /locus_tag="ACL29Z_000668"
     CDS             7881..8525
                     /gene="pcp"
                     /locus_tag="ACL29Z_000668"
                     /EC_number="3.4.19.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005829 - cytosol [Evidence IEA];
                     GO_function: GO:0008234 - cysteine-type peptidase activity
                     [Evidence IEA];
                     GO_function: GO:0016920 - pyroglutamyl-peptidase activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyroglutamyl-peptidase I"
                     /protein_id="HGR0069011.1"
                     /translation="MKVLVTGFEPFGGEKGNPALEAIKGLPAEIHGAEVRWLEVPTVF
                     HKSAQVLEEEMNRYQPDFVLCIGQAGGRTSLTPERVTINQDDACISDNEDNQPIDRPI
                     RPDGASAYFSSLPIKAMVQAIKKEGLPASVSNTAGTFVCSHLMYQALYLVEKKSPYVK
                     AGFMHIPYMMEQVVNRPTTPAMSLVDIRRGIEAAIGAIIEHGDQELKLVGGETH"
     gene            complement(8553..9410)
                     /locus_tag="ACL29Z_000669"
     CDS             complement(8553..9410)
                     /locus_tag="ACL29Z_000669"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF975 family protein"
                     /protein_id="HGR0069012.1"
                     /translation="MNYPKIDLKTIRQESKHFQADTPRLFLLYILPSMLVILSGFLNP
                     LSRIHGTVLEQPFFSILGQILQTYLFPLLVSFIGTILLTSSVYATLTLMKDSKTEPSV
                     KNSLALFDEERFSQTFLTLLLKRFYLFLWSIPNLLGIYLLFYSSFLAKKFVTLHPEFP
                     NLDLSSVETERFLMVFGLYFLASLILIIVGNILYIPQYYAYSQVEFLLCYSLDLGQVP
                     PRRILKTSRSFMKGYKFQHFVLDLQLLPWYFLNWITFGIASFSLLPYIQCTKIMFYRA
                     VLARKRPKA"
     gene            9540..10682
                     /gene="tgt"
                     /locus_tag="ACL29Z_000670"
     CDS             9540..10682
                     /gene="tgt"
                     /locus_tag="ACL29Z_000670"
                     /EC_number="2.4.2.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004298827.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0008479 - tRNA-guanosine(34) queuine
                     transglycosylase activity [Evidence IEA];
                     GO_process: GO:0006400 - tRNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA guanosine(34) transglycosylase Tgt"
                     /protein_id="HGR0069013.1"
                     /translation="MSDSPIKYRLIKKEKHTGARLGEIITPHGTFPTPMFMPVGTQAT
                     VKTQSPEELKEMGSGIILSNTYHLWLRPGDELIARAGGLHKFMNWDQPILTDSGGFQV
                     YSLADSRNITEEGVTFKNHLNGSKMFLSPEKAISIQNNLGSDIMMSFDECPQFYQPYD
                     YVKKSIERTSRWAERGLKAHRRPHDQGLFGIVQGAGFEDLRRQSAHDLVSMDFSGYSI
                     GGLAVGETHEEMNAVLDFTTQLLPENKPRYLMGVGAPDSLIDGVIRGVDMFDCVLPTR
                     IARNGTCMTSQGRLVVKNAQFAEDFTPLDPECDCYTCNNYTRAYLRHLLKADETFGIR
                     LTSYHNLYFLLNLMKQVRQAIMDDNLLEFREYFVEKYGYNKSGRNF"
     gene            10780..12597
                     /locus_tag="ACL29Z_000671"
     CDS             10780..12597
                     /locus_tag="ACL29Z_000671"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001220923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016747 - acyltransferase activity,
                     transferring groups other than amino-acyl groups [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acyltransferase family protein"
                     /protein_id="HGR0069014.1"
                     /translation="MRIKWFSLIRIIGLLLVLLYHFFQTIFPGGFFGVDVFFTFSGFL
                     ITALLIEEFSKNNEIDLIGFFRRRFYRIVPPVVLMVLVTMPFTFLVRQDYVAGIGGQI
                     AGVLGFMTNFYELLTGGSYESQFIPHLFVHNWSLAVEVHYYILWGLAVWFLSKQAKSN
                     GQLKGMVFLLSAVAFLISFFSMFIGSFLVTSYSSVYFSSLTHVYPFFLGSMLATIVGV
                     RQTTSLVKQLDKIWDLRKTLVVFGGGFGFLVLLTFFVKFTYLFAYLIGFLLASLAALA
                     MILAARVLHEKTHHIQESKIISFLADTSYAVYLFHWPFYIIFSQLTSNLLAVLLTLIC
                     SYGFASLSFYVLEPWIAGKNTPIVQTLRPLPYIHAILAAGTGILTIIVCTVTLLAPQV
                     GAFETDLTVNGLKQAATNIGQTKVMAERADANSLGIADGTMLIGDSVALRANTALQTA
                     LPGAQINAQVSVTTKTANEIMLNNSQNKFLPKTVVIATGVNNPENYKDDWDSIVKNLP
                     KGHHMILVTPYEGDKTKETYAIVEKAAAYMRELAEKTPYITIADWNQVAKEHPEIWAG
                     TDQVHFGSESSTIEAGAKLYADTIATALQTAQDKPVKSK"
     gene            12750..13901
                     /gene="nagA"
                     /locus_tag="ACL29Z_000672"
     CDS             12750..13901
                     /gene="nagA"
                     /locus_tag="ACL29Z_000672"
                     /EC_number="3.5.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008448 - N-acetylglucosamine-6-phosphate
                     deacetylase activity [Evidence IEA];
                     GO_process: GO:0006044 - N-acetylglucosamine metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylglucosamine-6-phosphate deacetylase"
                     /protein_id="HGR0069015.1"
                     /translation="MPNYIKADQFFYPHGVRRGGYLELVDGKFGKHVEQIPEGAEVID
                     YTGYSIAPGLVDTHIHGYAGVDVMDNNIEGTLHTMSEGLLSTGVTSFLPTTLTATYEQ
                     LLAVTENLGNHYKEATGAKIRGIYYEGPYFTETFKGAQNPTYMRDPGVEEFHSWQKAA
                     NGLLNKIALAPERDGVEDFVRTVTGEGVTVALGHSNATFDEAKKAVDAGASVWVHAYN
                     GMRGLTHRELGMVGAMYQLPHTYAELICDGHHVDPKACEILIKQKGTENIALITDCMT
                     AGGLEDGDYMLGEFPVVVANGTARLKSTGNLAGSILKLKDGLKNVVEWGIANPHEAVM
                     MASFNPAKSVHIDDVCGQIREGYDADFIVLDKDLELVATYLDGVKRYQA"
     gene            14064..15122
                     /locus_tag="ACL29Z_000673"
     CDS             14064..15122
                     /locus_tag="ACL29Z_000673"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000649458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-dependent alcohol dehydrogenase family
                     protein"
                     /protein_id="HGR0069016.1"
                     /translation="MKAYTYVKPGLASFVDVDKPVIRKPTDAIVRIVKTTICGTDLHI
                     IKGDVPTCQSGTILGHEGIGIVEEVGEGVSNFKKGDKVLISCVCACGKCYYCKKGIYA
                     HCEDEGGWIFGHLIDGMQAEYLRVPHADNTLYHTPEDLSDEALVMLSDILPTGYEIGV
                     LKGKVEPGCSVAIIGSGPVGLAALLTAQFYSPAKLIMVDLDDNRLETALSFGATHKVN
                     SSDPEKAIKEIYDLTDGRGVDVAIEAVGIPATFDFCQKIIGVDGTVANCGVHGKPVEF
                     DLDKLWIRNINVTTGLVSTNTTPQLLKALESHKIEPEKLVTHYFKLSEIEKAYEVFSK
                     AADHHAIKVIIENDISEA"
     gene            15273..15638
                     /locus_tag="ACL29Z_000674"
     CDS             15273..15638
                     /locus_tag="ACL29Z_000674"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1033 family protein"
                     /protein_id="HGR0069017.1"
                     /translation="MYRVIEMYGDFEPWWFLEGWEEDIVASRKFDQYYDALKYYKTCW
                     FRLEQESPLYKSRSDLMTIFWDPEDQRWCDECDEYLQQYHSLALLQDEQVIPDEKLRS
                     GYEKQTSQERNRSCRMKLK"
     gene            15714..16655
                     /gene="comGA"
                     /locus_tag="ACL29Z_000675"
     CDS             15714..16655
                     /gene="comGA"
                     /locus_tag="ACL29Z_000675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000249584.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence type IV pilus ATPase ComGA"
                     /protein_id="HGR0069018.1"
                     /translation="MVQEIAQEIIRSARKKGTQDIYFVPKLDAYELHMRVGDERCKIG
                     SYDFEKFAAVISHFKFVAGMNVGEKRRSQLGSCDYAYDHKIASLRLSTVGDYRGHESL
                     VIRLLHDEEQDLHFWFQDIEELGKQYRQRGLYLFAGPVGSGKTTLMHELSKSLFKGQQ
                     VMSIEDPVEIKQDDMLQLQLNEAIGLTYENLIKLSLRHRPDLLIIGEIRDSETARAVV
                     RASLTGATVFSTIHAKSIRGVYERLLELGVSEEELAVVLQGVCYQRLIGGGGIVDFAS
                     RDYQEHQAAKWNEQIDQLLKDGHITSLQAETEKISYS"
     gene            16603..17619
                     /gene="comGB"
                     /locus_tag="ACL29Z_000676"
     CDS             16603..17619
                     /gene="comGB"
                     /locus_tag="ACL29Z_000676"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000355375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence type IV pilus assembly protein ComGB"
                     /protein_id="HGR0069019.1"
                     /translation="MDISQVFRLRRKKLATAKQKNIITLFNNLFSSGFHLVETISFLD
                     RSALLDKQCVTQMRVGLSQGKSFSEMMESLGCSSAIVTQLSLAEVHGNLHLSLGKIEE
                     YLDNLAKVKKKLIEVATYPLILLGFLLLIMLGLRNYLLPQLDSSNIATQIIGNLPQIF
                     LGMVGLVSVLALLALTFYKRSSKMSVFSILARLPFIGIFVQTYLTAYYAREWGNMISQ
                     GMELTQIFQMMQEQGSQLFKEVGQDLAQTLKNGREFSQTIGTYPFFRKELSLIIEYGE
                     VKSKLGSELEIYAEKTWEAFFTRVNRTMNLVQPLVFIFVALIIVLLYAAMLMPMYQNM
                     EVNF"
     gene            17621..17947
                     /gene="comGC"
                     /locus_tag="ACL29Z_000677"
     CDS             17621..17947
                     /gene="comGC"
                     /locus_tag="ACL29Z_000677"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000738626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="comG operon protein ComGC"
                     /protein_id="HGR0069020.1"
                     /translation="MKKMMTFLKKAKVKAFTLVEMLVVLLIISVLFLLFVPNLTKQKE
                     AVNDKGKAAVVKVVESQAELYSLEKNEDASLRKLQADGRITEEQAKAYKEYNDKNGGA
                     NRKVND"
     gene            17940..18344
                     /gene="comGD"
                     /locus_tag="ACL29Z_000678"
     CDS             17940..18344
                     /gene="comGD"
                     /locus_tag="ACL29Z_000678"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000588002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence type IV pilus minor pilin ComGD"
                     /protein_id="HGR0069021.1"
                     /translation="MIKAFTMLESLLVLGLVSILALGLSGSVQSTFSAVEEQIFFMEF
                     EELYRETQKRSVASQQKTSLNLDGQTISNGSQKLPVPKGIQVPSGQSITFDRAGGNSS
                     LAKVEFQTSKGAIRYQLYLGNGKIKRIKETKN"
     gene            18307..18609
                     /gene="comGE"
                     /locus_tag="ACL29Z_000679"
     CDS             18307..18609
                     /gene="comGE"
                     /locus_tag="ACL29Z_000679"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000413380.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence type IV pilus minor pilin ComGE"
                     /protein_id="HGR0069022.1"
                     /translation="MEKLNALRKQKIRAVILLEAVVALAIFASIATLLLGQIQKNRQE
                     EAKILQKEEVLRVAKMALQTGQNQVNINGVEIQVFSSEKGLEVYHGSEQLLAIKEP"
     gene            18572..19033
                     /gene="comGF"
                     /locus_tag="ACL29Z_000680"
     CDS             18572..19033
                     /gene="comGF"
                     /locus_tag="ACL29Z_000680"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000250539.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence type IV pilus minor pilin ComGF"
                     /protein_id="HGR0069023.1"
                     /translation="MVQNSCWQSKSHKVKAFTLLESLLALLVISGGLLLFQAMSQLLI
                     SEVRYQQQSEQKEWILFVDQLEAELDRSQFEKVEGNRLYMKQDGKDIAIGKSKSDDFR
                     KTDASGRGYQPMVYGLKSAQITEDNQLVHFRFQFQKGLEREFIYRVEKEES"
     gene            19011..19457
                     /gene="comGG"
                     /locus_tag="ACL29Z_000681"
     CDS             19011..19457
                     /gene="comGG"
                     /locus_tag="ACL29Z_000681"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001851880.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence type IV pilus minor pilin ComGG"
                     /protein_id="HGR0069024.1"
                     /translation="MWKKKKVKAGVLLYAVTIAAIFSLLLQFYLNRQIAHYQDYALNK
                     EKLVAFAMAKRTKDKAEQESGEQVFNLGQVSYQNKKTSLVTTVRTSKSQYEFLFPSVK
                     IKEEKRDKKEEVATDSSEKAEKKNQKRSLKRKRIPSQFNYNALNPE"
     gene            19560..20147
                     /locus_tag="ACL29Z_000682"
     CDS             19560..20147
                     /locus_tag="ACL29Z_000682"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000679792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008168 - methyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HGR0069025.1"
                     /translation="MKHDFNHKAETFDSPKNIFLANLVCQAVEKQIDILSDKEILDFG
                     GGTGLLVLPLAKQAKSVTLVDISEKMLEQARLKVEQQAIKNIQFLEQDLPKNPLEKEF
                     DCLAVSRVLHHMPDLDAALSLFHQHLKEDGKLIIADFTKTEANHHGFDLAELENKLIE
                     HGFSSVHSQILYSAEDLFQGNHSEFFLTVAQKSLA"
     gene            20208..21161
                     /locus_tag="ACL29Z_000683"
     CDS             20208..21161
                     /locus_tag="ACL29Z_000683"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000345081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HGR0069026.1"
                     /translation="MDFEKIEQAYTYLLENVQVIQSDLATNFYDALVEQNSIYLDGET
                     ELNQVKDNNQALKRLALRKEEWLKTYQFLLMKAGQTEPLQANHQFTPDAIALLLVFIV
                     EELFKEEEITILEMGSGMGILGATFLTSLDKKVDYLGMEMDDLLIDLAASMADVIGLQ
                     AGFVQGDAVRPQMLKESDVVISDLPVGYYPDDAVASRHQVASSQEHTYAHHLLMEQGL
                     KYLKSDGYAIFLAPSDLLTSPQSDLLKEWLKEEASLVAMISLPENLFANTKQSKTIFI
                     LQKKNEIAVDPFVYPLASLQDASVLMKFKENFQKWTQGTEI"
     gene            21212..22402
                     /locus_tag="ACL29Z_000684"
     CDS             21212..22402
                     /locus_tag="ACL29Z_000684"
                     /EC_number="2.7.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000167779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000287 - magnesium ion binding [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008776 - acetate kinase activity
                     [Evidence IEA];
                     GO_process: GO:0006085 - acetyl-CoA biosynthetic process
                     [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acetate kinase"
                     /protein_id="HGR0069027.1"
                     /translation="MIKTIAINAGSSSLKWQLYLMPEEKVLAKGLIERIGLKDSISTV
                     KFDGRSEQQILDIENHTQAVKILLDDLIRFDIIKAYDEITGVGHRVVAGGEYFKESTV
                     VEGDVLEKVEELSLLAPLHNPANAAGVRAFKELLPDITSVVVFDTSFHTSMPEKAYRY
                     PLPTKYYTENKVRKYGAHGTSHQFVAGEAAKLLGRPLEDLKLITCHIGNGGSITAVKA
                     GKSVDTSMGFTPLGGIMMGTRTGDIDPAIIPYLMQYTEDFNTPEDISRVLNRESGLLG
                     VSANSSDMRDIEAAVAEGNHEASLAYEMYVDRIQKYIGQYLAVLNGADAIVFTAGVGE
                     NAENFRRDVISGISWFGCDVDDEKNVFGVTGDISTEAAKIRVLVIPTDEELVIARDVE
                     RLKK"
     gene            22403..22534
                     /locus_tag="ACL29Z_000685"
     CDS             22403..22534
                     /locus_tag="ACL29Z_000685"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000768902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0069028.1"
                     /translation="MKLKKYSIQGVGKVIFPASFSDEIVQNLAMIGFFEKYGIIVVI"
     gene            22551..22922
                     /gene="rnpA"
                     /locus_tag="ACL29Z_000686"
     CDS             22551..22922
                     /gene="rnpA"
                     /locus_tag="ACL29Z_000686"
                     /EC_number="3.1.26.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000739244.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000049 - tRNA binding [Evidence IEA];
                     GO_function: GO:0004526 - ribonuclease P activity
                     [Evidence IEA];
                     GO_process: GO:0008033 - tRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease P protein component"
                     /protein_id="HGR0069029.1"
                     /translation="MKKNFRVKREKDFKAIFKEGTSFANRKFVVYQLENQKNHFRVGL
                     SVSKKLGNAVTRNQIKRRIRHIIQNAKGSLVEDVDFVVIARKGVETLGYAEMEKNLLH
                     VLKLSKIYREGNGSEKETKVD"
     gene            22897..23721
                     /locus_tag="ACL29Z_000687"
     CDS             22897..23721
                     /locus_tag="ACL29Z_000687"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000727905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertase YidC"
                     /protein_id="HGR0069030.1"
                     /translation="MKKKLKLTSLLGLSLLIMTACATNGVTSDITAESADFWSKLVYF
                     FAEIIRFLSFDISIGVGIILFTVLIRTVLLPVFQVQMVASRKMQEAQPRIKALREQYS
                     GRDMESRTKLEQEMRKVFKEMGVRQSDSLWPILIQMPVILALFQALSRVDFLKTGHFL
                     WINLGSVDTTLVLPILAAVFTFLSTWLSNKALSERNGATTAMMYGIPVLIFIFAVYAP
                     GGVALYWTVSNAYQVLQTYFLNNPFKIIAEREAVVQAQKDLENRKRKAKKKAQKTK"
     gene            23740..24726
                     /gene="jag"
                     /locus_tag="ACL29Z_000688"
     CDS             23740..24726
                     /gene="jag"
                     /locus_tag="ACL29Z_000688"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000260012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0003723 - RNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding cell elongation regulator Jag/EloR"
                     /protein_id="HGR0069031.1"
                     /translation="MVVFTGSTVEEAIQKGLKELDIPRMKAHIKVISREKKGFLGLFG
                     KKPAQVDIEAISETTVVKANQQVVKGVPKKINDLNEPVKTVSEETVDLGHVVDAIKKI
                     EEEGQGISDEVKAEILKHERYASTILEETGHIEILNELQIEEAMREEAGADDLETEQD
                     QTENQDLKEMGLKVEQSYDIAQVATDVTAYVQTIIDDMDVEATLSNDYNRRSINLQID
                     TNEPGRIIGYHGKVLKALQLLAQNYLYNCYSRTFYITINVNDYVEHRAEVLQTYAQKL
                     AIRVLEEGRSHQTDPMSNSERKIIHRIISRMDGVTSYSEGDEPNRYVVVDTE"
     gene            24777..25400
                     /locus_tag="ACL29Z_000689"
     CDS             24777..25400
                     /locus_tag="ACL29Z_000689"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000932659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HI_0552 family protein"
                     /protein_id="HGR0069032.1"
                     /translation="MLNKIRDYLDFSGLQYRSPDKAGAEREKMLAFRHKGQEARKAFT
                     ELAKAFQASHPEWQLQQTSQWMNQAQRLRPHFWVYLQRDGQVTEPMMALRLYGTSTDF
                     GISLEVSFIERKKDEQTLGKQAKVLDIPTVKGIYYLTYSNGQSQRWEANEEKRRTLRE
                     KVRSQEVRKVLVKVDVPMTENSSEEEIVEGLLKSYSKILPYYLATRK"
     gene            25531..26988
                     /locus_tag="ACL29Z_000690"
     CDS             25531..26988
                     /locus_tag="ACL29Z_000690"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006153412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS ascorbate transporter subunit IIC"
                     /protein_id="HGR0069033.1"
                     /translation="MEVVSSVLNWFSSNILQNPAFFVGLLVLIGYALLKKPAHDVFSG
                     FVKATVGYMLLNVGAGGLVTTFRPILAALNYKFQIGAAVIDPYFRLAAANNKIVAEFP
                     DFVGTATTALLIGFGINILLVALRKITKVRTLFITGHIMVQQAATVSLMVLFLVPQLR
                     NAYGTAAIGIICGLYWAVSSNMTVEATQRLTGGGGFAIGHQQQFAIWFVDKVAGRFGK
                     KEESLDNLKLPKFLSIFHDTVVASATLMLVFFGAILLILGPDIMSNKEVITSGTLFNP
                     AKQDFFMYIIQTAFTFSVYLFVLMQGVRMFVSELTNAFQGISNKLLPGSFPAVDVAAS
                     YGFGSPNAVLSGFTFGLIGQLITIVLLIVFKNPILIITGFVPVFFDNAAIAVYADKRG
                     GWKAAVILSFISGVLQVALGALCVALLDLASYGGYHGNIDFEFPWLGFGYIFKYLGIV
                     GYVLVCLFLLVIPQLQFAKAKDKEKYYNGEVQEEA"
     gene            27011..27292
                     /locus_tag="ACL29Z_000691"
     CDS             27011..27292
                     /locus_tag="ACL29Z_000691"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000241469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HGR0069034.1"
                     /translation="MVKVLAACGNGMGSSMVIKMKVENALRKLNQTDFTVNSCSVGEA
                     KGLAVGYDIVIASLHLIQELEGRTNGKLIGLDNLMDDKEITEKLSQALQ"
     gene            27369..27854
                     /locus_tag="ACL29Z_000692"
     CDS             27369..27854
                     /locus_tag="ACL29Z_000692"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002267837.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HGR0069035.1"
                     /translation="MNLKQALIDNDSIRLGLEANDWKEAVKVAVDPLIESGAILPEYY
                     DAIIESTEEYGPYYILMPGMAMPHARPEAGVQSDAFSLITLQNPVVFSDGKEVSVLLA
                     LAATSSKIHTSVAIPQIIALFELEDSIARLQACQTKEDVLAMIEESKDSPYLEGLDLE
                     S"
     gene            27871..28536
                     /locus_tag="ACL29Z_000693"
     CDS             27871..28536
                     /locus_tag="ACL29Z_000693"
                     /EC_number="4.1.1.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000166733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000287 - magnesium ion binding [Evidence
                     IEA];
                     GO_function: GO:0016831 - carboxy-lyase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="3-keto-L-gulonate-6-phosphate decarboxylase
                     UlaD"
                     /protein_id="HGR0069036.1"
                     /translation="MTKRIPNLQVALDHSDLQGAIKAAVSVGQEVDIIEAGTVCLLQV
                     GSELAEVLRSLFPDKIIVADTKCADAGGTVAKNNAVRGADWMTCICCATIPTMEAALK
                     AIKTERGERGEIQIELYGDWTFEQAQLWLDAGISQAIYHQSRDALLAGETWGEKDLNK
                     VKKLIDMGFRVSVTGGLDVDTLKLFEGVDVFTFIAGRGITEAADPAGAARAFKDEIKR
                     IWG"
     gene            28540..29403
                     /locus_tag="ACL29Z_000694"
     CDS             28540..29403
                     /locus_tag="ACL29Z_000694"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000252119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016861 - intramolecular oxidoreductase
                     activity, interconverting aldoses and ketoses [Evidence
                     IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="L-ribulose-5-phosphate 3-epimerase"
                     /protein_id="HGR0069037.1"
                     /translation="MVRPIGIYEKATPTHFTWLERLNFAKELGFDFVEMSIDERDERL
                     ARLDWSKEERLEVVKAIYETGVRIPSICFSGHRRYPLGSKDPVLEEKSLELMKKCIEL
                     AQDLGVRTIQLAGYDVYYEEKSPQTRQRFIKNLRKACDWAEEAQVVLAIEIMDDPFIS
                     SIEKYLAIEKEIDSPFLFVYPDIGNVSAWHNDIYSEFYLGHHAIAALHLKDTYAVTES
                     SKGQFRDVPFGQGCVKWEEAFDILKETNYNGPFLIEMWSENCETVEETRAAVQEAQAF
                     LYPLIKKAGLM"
     gene            29405..30109
                     /locus_tag="ACL29Z_000695"
     CDS             29405..30109
                     /locus_tag="ACL29Z_000695"
                     /EC_number="5.1.3.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001077552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ribulose-5-phosphate 4-epimerase"
                     /protein_id="HGR0069038.1"
                     /translation="MNQVINAMRKRVCDANQSLPKHGLVKFTWGNVSEVNRELGVIVI
                     KPSGVDYDELTPENMVVTDLDGKILEGDLRPSSDLPTHVQLYKAWSEIGSVVHTHSTE
                     AVGWAQAGRDIPFYGTTHADYFYGSIPCARSLTKDEVEVAYEKDTGLVIVEEFEHRGL
                     NPVEVPGIVVRNHGPFTWGKNPENAVYHSVVLEEVSKMNRFTEQINPRVGPAPQYILE
                     KHYQRKHGPNAYYGQK"
     gene            30290..31963
                     /locus_tag="ACL29Z_000696"
     CDS             30290..31963
                     /locus_tag="ACL29Z_000696"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HGR0069039.1"
                     /translation="MVLDKASCDLLQYLMDQETSKTIMAISKDLKESRRKIYYHIDKI
                     NAALVDEALHIISIPRIGIHLTEEQRDACCKLLSEVDSYDYIMSAHERMMIMLLWIGI
                     SKERITIEKLIELTEVSRNTVLNDLNSIRYQLTLEQYQVILQVSKSQGYHLHAHPLNK
                     IQYLQSLLYHIFMEENATFVSILEDKMKERLDDECLLSVEMNQFFKEQVPLVEQDLGK
                     KINHHEITFMLQVLPYLLLSCHNVEQYQERHQDIEKEFSLIRKRIEYQVSKKLGERLF
                     QKFEISLSGLEVSLVAVLLLSYRKDLDIHAESDDFRQLKLALEEFIWYFESQIRMEIE
                     NKDDLLRNLMIHCKALLFRKTYGIFSKNPLTKQIRSKYGELFLVTRKSAEILEGAWFI
                     RLTDDDIAYLTIHIGGFLKYTPSSQKNMKKVYLVCDEGVAVSRLLLKQCKLYFPNEQI
                     DTVFTTEQFKSVEDIAQVDVVITTNDDLDSRFPILRVNPILEAEDILKMLDYLKHNIF
                     RNESKSFSENLSSLISSYIVDSKLASKFQEEVQTLINQEIVVQAFLEDI"
     gene            32075..33166
                     /gene="ulaG"
                     /locus_tag="ACL29Z_000697"
     CDS             32075..33166
                     /gene="ulaG"
                     /locus_tag="ACL29Z_000697"
                     /EC_number="3.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030145 - manganese ion binding [Evidence
                     IEA];
                     GO_function: GO:0035460 - L-ascorbate 6-phosphate
                     lactonase activity [Evidence IEA];
                     GO_process: GO:0019854 - L-ascorbic acid catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="L-ascorbate 6-phosphate lactonase"
                     /protein_id="HGR0069040.1"
                     /translation="MPNVKEITRESWILATFPEWGTWLNEEIEEEVVPEGNFAMWWLG
                     NCGTWIKTPAGANVVMDLWSNRGKSTKKVKDMVRGHQMANMAGVRKLQPNLRVQPMVI
                     DPFAINELDYYLVSHFHSDHIDPYTAAAILNNPKLEHVKFIGPYHCGRIWEGWGVPKE
                     RIIVVKPGDTIELKDMKIHAVESFDRTCLVTLPVNGADETGGELAGLAVTDEEMAQKA
                     VNYIFETPGGTIYHGADSHFSNYFAKHGKDFKIDVALNNYGENPVGIQDKMTSIDLLR
                     MAENLRTKVIIPVHYDIWSNFMASTNEILELWKMRKDRLQYDFHPFIWEVGGKYTYPQ
                     DQHLVEYHHPRGFDDCFEQDSNIQFKALL"
     gene            33280..35256
                     /gene="tkt"
                     /locus_tag="ACL29Z_000698"
     CDS             33280..35256
                     /gene="tkt"
                     /locus_tag="ACL29Z_000698"
                     /EC_number="2.2.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004185329.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004802 - transketolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase"
                     /protein_id="HGR0069041.1"
                     /translation="MSNLSVNAIRFLGIDAINKANSGHPGVVMGAAPMAYSLFTKQLH
                     INPAQPNWINRDRFILSAGHGSMLLYALLHLSGFEDVSMDEIKSFRQWGSKTPGHPEF
                     GHTAGIDATTGPLGQGISTATGFAQAERFLAAKYNREGYNIFDHYTYVICGDGDLMEG
                     VSSEAASYAGLQKLDKLVVLYDSNDINLDGETKDSFTESVRDRYNAYGWHTALVENGT
                     DLEAIHAAIETAKASGKPSLIEVKTVIGYGSPNKQGTNAVHGAPLGADETASTRQALG
                     WDYEPFEIPEQVYADFKEHVADRGASAYQAWTKLVADYKEAHPELAAEVEAIIDGRDP
                     VEVTPADFPALENGFSQATRNSSQDALNVVAAKLPTFLGGSADLAHSNMTYIKTDGLQ
                     DDTNRLNRNIQFGVREFAMGTILNGMALHGGLRVYGGTFFVFSDYVKAAVRLSALQGL
                     PVTYVFTHDSIAVGEDGPTHEPVEHLAGLRAMPNLNVFRPADARETQAAWYLAVTSEK
                     TPTALVLTRQNLTVEDGTDFDKVAKGAYVVYENAADFDTILIATGSEVNLAVSAAKEL
                     ASQGEKIRVVSMPSTDVFDKQDAAYKEEILPNAVRRRVAVEMGASQNWYKYVGLDGAV
                     LGIDTFGASAPAPKVLAEYGFTVENLVKVVRNLK"
     gene            35373..35672
                     /gene="yajC"
                     /locus_tag="ACL29Z_000699"
     CDS             35373..35672
                     /gene="yajC"
                     /locus_tag="ACL29Z_000699"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001069053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit YajC"
                     /protein_id="HGR0069042.1"
                     /translation="MNPNITFLIMLVGMMALMFFMQRSQKKQAQKRMESLNKLQKGYE
                     VITIGGLYGTVDEVDTEKGTIVLDVDGVYLTFELAAIKTVLPLKETASLEGAIEK"
     gene            35719..36147
                     /locus_tag="ACL29Z_000700"
     CDS             35719..36147
                     /locus_tag="ACL29Z_000700"
                     /EC_number="3.1.3.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000737444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004725 - protein tyrosine phosphatase
                     activity [Evidence IEA];
                     GO_process: GO:0006470 - protein dephosphorylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="low molecular weight
                     protein-tyrosine-phosphatase"
                     /protein_id="HGR0069043.1"
                     /translation="MKKLVFVCLGNICRSPMAEFVMKSMTDNYEIQSRATSSWEHGNP
                     IHKGTQGIFQEYEIPYDKNKTSLQISKEDFEAFDYIIGMDASNISDLRQMCPVDCQDK
                     IYSFSSESVPDPWYTGDFEETYRRVQEGCQAWLERLEKES"
     gene            36149..36559
                     /locus_tag="ACL29Z_000701"
     CDS             36149..36559
                     /locus_tag="ACL29Z_000701"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000427064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MORN repeat-containing protein"
                     /protein_id="HGR0069044.1"
                     /translation="MENLTNFYEKYRVYLTRPRLELLAVVTIVFCAVLVFFLNIPGKG
                     VLKLDNGTIVYDGSLVRGKMNGQGTITFQNGDQYTGGFNNGAFNGKGTFQSKEGWTYE
                     GDFVNGQAEGKGKLTTEQEVVYEGTFKQGVFQQK"
     gene            36859..39510
                     /gene="adhE"
                     /locus_tag="ACL29Z_000702"
                     /gene_synonym="adhC"
     CDS             36859..39510
                     /gene="adhE"
                     /locus_tag="ACL29Z_000702"
                     /gene_synonym="adhC"
                     /EC_number="1.1.1.1"
                     /EC_number="1.2.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000763984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004022 - alcohol dehydrogenase (NAD+)
                     activity [Evidence IEA];
                     GO_function: GO:0016620 - oxidoreductase activity, acting
                     on the aldehyde or oxo group of donors, NAD or NADP as
                     acceptor [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0006066 - alcohol metabolic process
                     [Evidence IEA];
                     GO_process: GO:0015976 - carbon utilization [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional acetaldehyde-CoA/alcohol
                     dehydrogenase"
                     /protein_id="HGR0069045.1"
                     /translation="MADKKTVTPEEKKLVAEKHVDELVQKALVALEEMRKLDQEQVDY
                     IVAKASVAALDAHGELALHAFEETGRGVFEDKATKNLFACEHVVNNMRHTKTVGVIEE
                     DDVTGLTLIAEPVGVVCGITPTTNPTSTAIFKSLISLKTRNPIVFAFHPSAQESSAHA
                     ARIVRDAAIAAGAPENCVQWITQPSMEATSALMNHEGVATILATGGNAMVKAAYSCGK
                     PALGVGAGNVPAYVEKSANIRQAAHDIVMSKSFDNGMVCASEQAVIIDKEIYDEFVAE
                     FKSYHTYFVNKKEKALLEEFCFGVKANSKNCAGAKLNADIVGKPATWIAEQAGFTVPE
                     GTNILAAECKEVGENEPLTREKLSPVIAVLKSESREDGITKARQMVEFNGLGHSAAIH
                     TADEELTKEFGKAVKAIRVICNSPSTFGGIGDVYNAFLPSLTLGCGSYGRNSVGDNVS
                     AINLLNIKKVGRRRNNMQWMKLPSKTYFERDSIQYLQKCRDVERVMIVTDHAMVELGF
                     LDRIIEQLDLRRNKVVYQIFADVEPDPDITTVNRGTEIMRAFKPDTIIALGGGSPMDA
                     AKVMWLFYEQPEVDFRDLVQKFMDIRKRAFKFPLLGKKTKFIAIPTTSGTGSEVTPFA
                     VISDKANNRKYPIADYSLTPTVAIVDPALVLTVPGFVAADTGMDVLTHATEAYVSQMA
                     SDYTDGLALQAIKLVFENLESSVKNADFHSREKMHNASTIAGMAFANAFLGISHSMAH
                     KIGAQFHTIHGRTNAILLPYVIRYNGTRPAKTATWPKYNYYRADEKYQDIARMLGLPA
                     STPEEGVESYAKAVYELGERIGIQMNFRDQGIDEKEWKEHSRELAFLAYEDQCSPANP
                     RLPMVDHMQEIIEDAYYGYKERPGRRK"
BASE COUNT        12094 a         7093 c         8943 g        11608 t
ORIGIN      
        1 tatattttgg aagggtagcg aagaggctaa acgcggcgga ctgtaaatcc gctccttcgg
       61 gttcgggggt tcgaatccct ccccttccat tttacgggca tagtttaaag gtagaactaa
      121 ggtctccaaa accttcagtg tgggttcaat tcctactgcc cgtgttaata gaattatggc
      181 gggtgtggtg aagtggttaa cacaccagat tgtggctctg gcatgcgtgg gttcgatccc
      241 catcactcgc ctattttata ttattggggt atagccaagc ggtaaggcaa gggactttga
      301 ctccctcatg cgttggttcg aatccagcta ccccagttac tatttgccgg cgtggcggaa
      361 ttggcagacg cgctggactc aaaatccagt gtccgcaagg acgtgccggt tcgaccccgg
      421 ccgccggtat agtatagtgt taggaacgtt gttattcttc gttccttttt tatattattt
      481 ttggtataat tatagttatt caaattttat ttagattaag aaagtgtagg gtagtatgtc
      541 ttgttctatc gatttattaa aacatcggta tttgaaaaat attaaagaaa atcctgaatt
      601 gtttgtcgga attgagttgg agtatcctgt tgcaagttta gaaggggatg ccacagatgt
      661 tgaagttata aaggatctat ttcattattt agtttctact ttggatctca ccgtagcaaa
      721 ggtagatgat tttagcaatc tgatccagtt agtagatccg ataaatcagg atgctatttt
      781 gtttgaagtt tcctatacaa cgattgagtt tgcatttggt aaggctgaaa cgattcaaga
      841 ggtcgaaaat cgtttcaata attatatgaa tgtaattcag agaaagttag ctgaatcaaa
      901 tcatgctatt gttggctgtg gtatccatcc caactgggat aaaaatgaga attgtccagt
      961 ggcttatcca cgctatcaga tgttgatgga ttatttgaat ttgagtagaa atattattaa
     1021 atcagattta catcatttcc ctgaatatgg tacttttatc tgtgggagcc aggttcagct
     1081 ggatatttca aaaaccaact acttacgggt gattaatgct tttactcaaa ttgaagcggc
     1141 taaggcttat ttatttgcaa actctgagtt ttcgggtgcg gattgggata cgaaaatttc
     1201 aagggatatt ttctgggaag aatctatgca tggtatctat ccagagaatg ttggggtcaa
     1261 tgctagactc cttaatgatg aagctgattt ttttgactat ctaaatcatt ctgcgatttt
     1321 tactgcggaa cgtgatgggc agacctatta tttttatcct attcaggctg gggactattt
     1381 ggctacgccc gaaatccaag catttgctct gaatggggat gaggttatta tttaccccca
     1441 agagaaggat tttgaaactc atcgtagtta ccagtaccaa gatttaacga ctcgaggaac
     1501 agttgagttt cgtagtgtgt gtacacagcc acttgatagg acttttgctt ctgcagcttt
     1561 tcacttggga ttattggtta atttagacaa gttagaagct tacttagaaa cagcaccttt
     1621 ctttaaagta tttggttatg attacaagtc tttaaggaga caattttcta agaaaaatct
     1681 tacagatgag gaagaaacta cgattattga attttccaaa gacttactcc tactagctga
     1741 ggagggacta gtggtgagaa ataaggaaga aatgacctat ttacagcctt tgagagaaga
     1801 attgagccta taatttctct tataaaggga gaattttctg aaaaatcatg atataatgga
     1861 cgagactata gataaaggat agagagtaat gacattagtt tatcaatcaa cgcgtgatgc
     1921 caacaataca gtaactgcta gccaagcaat tttgcaaggt ttggcgacgg acggcggttt
     1981 gtttacaccg gttacttatc caaaggtaga tttggacttt gacaaattga aagatacttc
     2041 ttaccaggaa gttgctaagc tagttttgtc agcattttta gatgacttta cagctgagga
     2101 gttggactac tgtatcaaca atgcctacga tagcaaattt gatactccag ctattgcacc
     2161 attagtgaaa ttagatgggc aatacaattt ggaacttttc catggttcaa cgattgcctt
     2221 taaggatatg gccttgtcta ttttgccata ctttatgacg actgctgcta agaaacatgg
     2281 tttggagaac aagattgtta tcttgacagc gacatctggt gacacgggga aagctgctat
     2341 ggcggggttt gcggatgtgc ctggtactga gattatcgtc ttttatccaa aggatggtgt
     2401 cagcaagatt caagagttac aaatgaccac tcaaactggc gacaatactc atgttattgc
     2461 tattgatggt aactttgacg atgcgcaaac aaatgtgaag cacatgttta acgacgtggc
     2521 tcttcgtgaa aaattgacta ccaacaagtt gcaattttca tcagctaact ctatgaacat
     2581 tggtcgtctg gtgccacaaa ttgtttatta tgtttatgct tacgctcaat tggttaagac
     2641 tggtgaaatt gtagctggtg aaaaggttaa cttcacagta ccaacaggaa actttggaaa
     2701 tatcttggct gccttttatg ccaaacaaat tggtttgcca gttggtaaat taatctgtgc
     2761 ttcaaatgac aataatgtct tgacagactt ctttaaaaca cgtgtctatg acaaaaaacg
     2821 tgagtttaag gtaacaacca gcccatctat ggatatcttg gtatcttcaa acttggagcg
     2881 cttgattttc catcttttgg gaaataatgc tgaaaagaca gttgaactta tgaatgcctt
     2941 gaacacgcaa ggacaatata agttgacaga ctttgatgca gagattttgg acctctttgc
     3001 agctgaatat gcgactgagg aagaaacggc agcagagatc aagcgtgttt gtgagttaga
     3061 ttcttatatc gaggaccctc atacagctgt tgcttcagca gtttataaaa aataccaatc
     3121 ggccactgga gatgtaacta agacagtgat tgcttcaaca gctagtccat acaagttccc
     3181 agtagttgca gtagaagctg taactggaaa agcaggttta acagactttg aagccttggc
     3241 tcaattacat gaaatctcag gcgttgcagt gccaccagca gttgatgggc ttgaaatagc
     3301 tccaattcgt cacaagacaa cagtggcagc tgctgacatg caagcagcgg ttgaggctta
     3361 tttaggactt taagacagag ggagcaaact cggttgggaa accaactgag tttcttttca
     3421 tcaggaggag agattgttta agaaaaataa agacattctt aatattgcat tgccagctat
     3481 gggtgaaaac tttttgcaga tgctaatggg aatggtggac agttatttgg ttgctcattt
     3541 aggattgata gctatttcag gggtttcagt agctggtaat attatcacca tttatcaggc
     3601 gattttcatc gctctgggag ctgctatttc cagtgttatt tcaaaaagca tagggcagaa
     3661 agaccagtcg aagttggcct atcatgtgac tgaggcgttg aagattacct tactattaag
     3721 tttcctttta ggatttttgt ccatcttcgc tgggaaagag atgataggac ttttggggac
     3781 ggagagggat gtagctgaga gtggtggact gtatctatct ttggtaggcg gatcgattgt
     3841 tctcttaggt ttaatgacta gtctgggagc cttgattcgt gcaacgcata atccacgttt
     3901 gcctctctat gttagttttt tatccaatgc cttgaatatt cttttttcaa gtctagctat
     3961 ttttgttctg gatatgggga tagctggtgt tgcttggggg acaattctgt ctcgtttggt
     4021 tggtcttgtg attttgtggt cacaattaaa actgccttat gggaagccaa cttttggttt
     4081 agataaggaa ctgttgacct tggctttacc agcagctgga gagcgactta tgatgagggc
     4141 tggagatgta gtgatcattg ccttggtcgt ttcttttggg acggaggcag ttgctgggaa
     4201 tgcaatcgga gaagtcttga cccagtttaa ctatatgcct gcctttggcg tcgctacggc
     4261 aacggtcatg ctgttggccc gagcagttgg agaggatgat tggaaaagag tcgctagttt
     4321 gagtaaacaa accttttggc tttctctgtt cctcatgttg cccctgtcct ttagtatata
     4381 tgtcttgggt gtaccattaa ctcatctcta tacgactgat tctctagcgg tggaggctag
     4441 tgttctagtg acactgtttt cactacttgg aacccctatg acgacaggaa cagtcatcta
     4501 tacggcagtc tggcagggat taggaaatgc acgcctccct ttttatgcga caagtatagg
     4561 catgtggtgt atccgcattg gaacaggata tctgctgggg attgtgcttg gttggggctt
     4621 gcctggtatt tgggcagggt ctctcttgga taatggtttt cgctggttat ttctacgcta
     4681 tcgttaccag cgctatatga gcttgaaagg ataggaaatg caaaaaacag cttttatttg
     4741 ggatttagac gggactttat tggactctta cgaagcgatt ttatcaggga ttgaggagac
     4801 ttttgctcag ttttctattc cttatgataa ggagaaggtg agagagttta tcttcaagta
     4861 ttcggtgcaa gatttgcttg tgcgggtggc agaagataga aatctggatg ttgaggtgct
     4921 aaatcaggtg cgtgcccaga gtctggctga gaagaatgct caggtagttt tgatgccagg
     4981 tgcgcgtgag gtgctagctt gggcagacga atcaggaatt cagcagttta tatatactca
     5041 taaggggaac aacgctttta ccattctcaa ggacttgggg gtggaatcct attttacaga
     5101 gattttaacc agtcagagtg gctttgtgcg gaagccaagt ccagaagcgg ctacctatct
     5161 gctagataag tatcagttga attctgataa tacttattat ataggggatc ggactctgga
     5221 tgtggaattt gcccagaata gtgggattca aagtatcaac tttttagagt ctacttatga
     5281 agggaatcac aggattcaag cgttagcaga tatttcccgt atttttgaga ctaagtgata
     5341 aaaagattgt gtcagttttg tgacagagac ctaacaaact atttcaagta acctagtttg
     5401 ttacaaggaa tagacagttc tgttaaatag gcccgagagg gctttttttc tacatttttt
     5461 gtgttatcat agacaggtac tcatttgaaa ggaatttgaa agaatgaaga aaagaatgtt
     5521 attagcgtca acagtagcct tgtcatttgc cccagtattg gcaactcaag cagaagaagt
     5581 tctttggact gcacgtagtg ttgagcaaat ccaaaacgat ttgactaaaa cggacaacaa
     5641 aacaagttat accgtacagt atggtgatac tttgagcacc attgcagaag ccttgggtgt
     5701 agatgtcaca gtgcttgcga atctgaacaa aatcactaat atggacttga ttttcccaga
     5761 aactgttttg acaacgactg tcaatgaagc agaagaagta acagaagttg aaatccaaac
     5821 acctcaagca gactctagtg aagaagtgac aactgcgaca gcagatttga ccactaatca
     5881 agtgaccgtt gatgatcaaa ctgttcaggt tgcagacctt tctcaaccaa ttgcagaagc
     5941 tccaaaagaa gtagcatcaa gttcagaagt tacaaagaca gtgattgctt ctgaagaagt
     6001 ggcaccatct acgggcactt ctgtcccaga ggagcaaacg gccgaaacaa gcagtgcagt
     6061 tgcagaagaa gctcctcagg aaacgactcc agctgagaag caggaaacac aagcaagccc
     6121 tcaagctgca tcagcagtgg aagcaactac aacaagttca gaagcaaaag aagtagcatc
     6181 atccaatgga gctacagcag cagtttctac ttatcaacca gaagagacga aagtaatttc
     6241 aacaacttac gaggctccag ctgcgcccga ttatgctgga cttgcagtag caaaatctga
     6301 aaatgcaggt cttcaaccac aaacagctgc ctttaaagaa gaaattgcta acttgtttgg
     6361 cattacatcc tttagtggtt atcgtccagg agacagtgga gatcacggaa aaggtttggc
     6421 tatcgacttt atggtaccag aacgttcaga attaggggat aagattgcgg aatatgctat
     6481 tcaaaatatg gccagccgtg gcattagtta catcatctgg aaacaacgtt tctatgctcc
     6541 attcgatagc aaatatgggc cagctaacac ttggaaccca atgccagacc gtggtagtgt
     6601 gacagaaaat cactatgatc acgttcacgt ttcaatgaat ggataaaccc gacttgataa
     6661 catcattttg acgaatgaga tctagctttc gtgatggaaa gcgattctcg ttcgtttttt
     6721 ctttgtcata ctcttcgaaa atctcttcaa accacgtcag ttttatctga aacctcaaag
     6781 ctgtgctttg agcaacctgc gactagcttc ctagtttgct ttttgatttt cattgagtat
     6841 caatttgaat ggaaaatgga aagttatcat cttgtaatga gttaagcaac attcttgcaa
     6901 tctattttac tttatatcac aattaattag tcaaatattg ataaatcaat aaaaagagag
     6961 gggaagaaat gctagagatt caagatttac tgtatcaact ccgcttgtct gagcaagcga
     7021 gtacgcaatt gtttgaaaaa aggcttggga ttagtttgac acggtatcag attttactgt
     7081 ttttgctgga gcattctcct tgtaaccaaa tggcgattca ggagcgtttg aaaattgatc
     7141 aggctgcttt gacacggcat ttcaagattt tggaaacgga aggtttggtg gagcgtcatc
     7201 gtaatcctga aaatcagcgg gaagtgttgg tagaggctgc gaagtatgcc aaggagcagt
     7261 tagtggtgaa tccccctctg caacatatca aggttaagga agagatggaa agtatcttaa
     7321 cagagtttga gagaacagaa ctcagccgtt tattaaataa attggttttg ggtattgaaa
     7381 atatagaaat ttaaggagaa atagatgtca attattacaa ttattttaac aacgatcgtt
     7441 gctttggagc atttttacat tttttatttg gaaagtattg ctacgcgatc agatgcgact
     7501 agtcgtgtat ttaatatgga aaaggaagaa ttggctcatc cgtcagtaag ttcattgttc
     7561 aaaaatcaag ggatttataa ggctctgcta ggagtctttc tctggtatgg catttatttc
     7621 tcacagaatt tagaaattgt gactattttt gtcttatttg tgattggtgc tgcgacttac
     7681 ggctctttaa cagcggataa aaaaattatt ttgaagcaag gtggatcagc tattttggcc
     7741 ttgattagta ttttactctt taaaatacac ttgaaggtcg attctaatct cgctaatcct
     7801 ttttaatcca gaataaggga aatatgttat acttgttttt aagaaaaaag tctcattgaa
     7861 ttggttttga ggagttagaa atgaaagtat tagtgacagg ttttgagccc tttggagggg
     7921 aaaagggcaa tccagctttg gaggccatta aaggtttacc agctgaaatc catggtgctg
     7981 aggtccgttg gctagaggtg ccgacagttt ttcacaaatc tgctcaagta ttggaagaag
     8041 agatgaatcg ttatcaacct gactttgtcc tttgtattgg gcaagctggt ggaagaacta
     8101 gtttgacacc tgaacgagtg accattaatc aagacgatgc atgcatttct gataacgaag
     8161 ataatcaacc gattgaccgt cccattcgcc cagatggtgc ttcggcctac tttagtagtt
     8221 tgccgattaa agcgatggtt caagctataa aaaaagaggg cttaccggcc tctgtttcca
     8281 atacggcagg gacttttgtc tgcagccatt tgatgtatca ggctctctat ttggtagaaa
     8341 agaaatctcc atatgttaag gcaggtttta tgcatattcc ttatatgatg gaacaggtgg
     8401 tgaacagacc gactactcca gctatgagtt tagtggatat tcggcgaggg atagaagcag
     8461 caatcggcgc tataatagaa catggagatc aggaactcaa gttggtaggc ggagaaactc
     8521 attgatagaa aaaagcttga ggggaaaaac cttcaagctt ttggacgttt tcgggccaat
     8581 actgctcggt aaaacataat tttagtgcat tggatataag gtaggagtga aaaactagca
     8641 atgccaaagg taatccaatt gaggaagtac caaggaagaa gctgtaaatc taggacaaag
     8701 tgctggaact tgtagccctt cataaaggaa cggctagttt ttaggattcg tcttggtggg
     8761 acctgtccta ggtctagact ataacagaga agaaattcca cctgtgaata ggcataatac
     8821 tgtggaatat agaggatatt tcctacaatg atcaagatga gacttgcaag aaagtagagt
     8881 ccaaagacca tgaggaaacg ctcggtttca actgatgaga gatctagatt tggaaactca
     8941 ggatgtaggg tgacgaattt tttggctaaa aagctactat aaaagaggag gtaaatccca
     9001 agtaaattag ggatactcca taaaaagaga tagaaacgtt tgagaagtag ggtcaaaaag
     9061 gtttgagaaa agcgctcctc atcaaagaga gctaggctgt tttttacaga tggctccgtt
     9121 ttagaatctt tcatgagtgt cagtgttgca tagacggaac tggtcaaaag aatagtcccg
     9181 ataaaggaga ctagtagagg aaagaggtag gtttgaagta tttggccaag tatgctgaaa
     9241 aatggctgtt ctaaaacagt cccgtggatc cgagataagg gattaagaaa accagataag
     9301 atgaccagca tactgggaag gatatagagg agaaagagac ggggggtgtc agcctgaaaa
     9361 tgttttgact cctgacgaat tgtttttaaa tcaatttttg gatagttcat tctcttatta
     9421 taccatagtt cttatacata gttcgtgaca gttcctactt tttttgataa aatcatacag
     9481 tgtgtccttg ggcacactgt atgaactggg actgtctttc ccagcttcgg aggtaaaaaa
     9541 tgtcagattc accaatcaaa tatcgtttga ttaagaaaga aaaacacaca ggagctcgtc
     9601 tgggagaaat catcactccc cacggtacct ttccgacacc tatgtttatg ccagttggga
     9661 cacaagccac tgtcaaaact cagtcacctg aagaattgaa ggagatgggt tcgggaatta
     9721 tcctatcaaa cacctatcat ctctggcttc gccctggaga tgaactcatt gcacgcgctg
     9781 gtggtctcca caagttcatg aattgggacc agcctatctt gacagatagt ggtggttttc
     9841 aggtttattc tttagcagat agccgtaata tcacagaaga aggagtaacc tttaaaaatc
     9901 atctaaatgg ttctaagatg ttcctatccc cagaaaaagc catctctatt cagaataatc
     9961 tgggttcaga catcatgatg tcctttgatg aatgtcctca gttttatcaa ccttatgact
    10021 acgttaagaa atcgatcgag cgtaccagcc gttgggctga gcgtggtttg aaggctcacc
    10081 gtcgtccaca tgaccaaggt ttgtttggaa ttgtgcaagg tgcaggattt gaagaccttc
    10141 gccgccaatc agctcatgat cttgtcagca tggatttctc aggctactct atcggtggtt
    10201 tggcagtggg agaaacccat gaagagatga atgcggtctt ggactttaca actcaactgc
    10261 tgcctgaaaa taaacctcgt tatctgatgg gtgtgggagc gccagatagc ttgatcgatg
    10321 gggtcattcg tggggtggat atgtttgact gtgtcttacc gactcgaatt gctcgtaacg
    10381 ggacttgtat gaccagtcaa ggacgtttgg ttgtgaaaaa tgcccagttt gctgaggact
    10441 ttacgccact ggatcctgag tgtgattgct acacatgtaa taactataca cgcgcttacc
    10501 ttcgtcacct gctcaaggct gatgaaacct ttggtatccg cttgactagc taccacaatc
    10561 tttacttctt gcttaacctg atgaagcaag tgcgacaagc catcatggat gacaatctct
    10621 tggaattccg tgagtatttt gtggaaaaat atggctataa taagtcagga cgtaatttct
    10681 aaaatggaat tgatataaaa aaatcctaag ttttctctta ggatttttct tctttttttg
    10741 atagaataaa gtgtacaatg aaaggaagaa taaactcgta tgcgcattaa atggttttcc
    10801 ttgattagga ttataggttt acttttggta ctcttgtatc acttctttca gacgatcttt
    10861 cctggaggat ttttcggggt agatgtcttt ttcacatttt caggtttcct gattacagct
    10921 ctactcattg aagaattttc taagaacaat gagattgatt tgataggatt ttttagaaga
    10981 cgcttttatc ggattgtgcc acctgtggtt ttgatggtct tggtgaccat gccttttact
    11041 ttcttggttc gccaagacta tgttgctgga attggtggcc agattgcggg cgtcttaggc
    11101 tttatgacca acttctatga actcctaaca ggtgggagtt atgaatctca gttcattcct
    11161 catttgtttg ttcataattg gagtttggca gttgaggttc actactatat tctttgggga
    11221 ttggcagttt ggttcttatc caaacaagct aaatcaaatg gtcagttgaa ggggatggtc
    11281 tttctcttat ctgctgttgc cttcttgatc agtttcttct ccatgtttat tggtagtttt
    11341 ctagtgacct cttattcctc tgtttatttc tccagtttaa ctcatgtcta tccattcttt
    11401 ttaggaagta tgttagcaac tattgtaggc gttcgtcaga cgacttccct cgtcaagcag
    11461 ttggataaaa tctgggattt acgaaagact ttggtagttt ttggaggagg ctttggtttc
    11521 ctagttcttt tgactttctt tgtcaaattc acttatcttt ttgcctatct tatcggcttc
    11581 ttacttgcca gtcttgcagc tcttgccatg attctggcgg cgcgtgtctt acatgaaaag
    11641 acacatcata tacaggagtc gaagattatc agctttttag cggatactag ctatgcggtt
    11701 tatcttttcc attggccttt ctatatcatt ttctcacagt tgacatcaaa tcttcttgct
    11761 gtattactga ctctgatttg ttcttatggc tttgccagtc tgtcatttta tgtattggaa
    11821 ccttggattg caggcaagaa cacacctatt gtccaaaccc ttcgtcccct gccttatatt
    11881 cacgcaattc ttgcagcagg tacaggaatc ttgaccatca ttgtctgcac ggtgaccttg
    11941 ttggcaccac aagtgggagc gtttgagaca gacttgactg tcaatggctt gaagcaagct
    12001 gcaacaaata ttggccagac caaggtgatg gcagaacggg cagatgcaaa cagtttggga
    12061 attgctgatg gcactatgtt aattggtgac tcagtggctt taagggcaaa tacagcacta
    12121 cagacagctc ttcctggagc acagattaac gcgcaggtca gcgtaacaac caagaccgca
    12181 aatgaaatca tgctaaataa tagccagaat aaatttttac ctaagacggt ggtcattgcg
    12241 actggggtaa ataatcctga gaattacaag gatgactggg acagtatcgt gaaaaatctt
    12301 cctaagggac accatatgat tttggtgact ccttatgagg gagataagac aaaagagacc
    12361 tatgccatcg ttgagaaggc tgctgcctat atgagagaat tggcagagaa gacaccttac
    12421 attacgatag cagattggaa tcaagttgcg aaagagcatc cagaaatttg ggctggaaca
    12481 gaccaggttc atttcgggag tgagagtagc actatcgaag caggagcaaa attgtatgca
    12541 gatacgattg ccacagcttt gcagacagct caagacaagc cggttaaatc aaaataactt
    12601 gtattaaaaa agagaagagt tggagaaatc cagctctttt aaaatatctc caaaaaatag
    12661 gtctatacca tttacaaata aaaaagaaag gtttataatg taattgacat aataaattgt
    12721 agaatcaatc ttttaaggag gttaacatta tgcctaacta tattaaagcg gatcagtttt
    12781 tctacccaca cggagttcgt cgaggtggtt acttggaact tgtggacggc aagtttggga
    12841 aacatgtaga gcagattcct gaaggggctg aggtgattga ctatacaggt tatagcattg
    12901 ccccaggtct tgtggatact catattcatg gatatgcagg tgtagatgtg atggacaaca
    12961 acattgaagg tacattgcat actatgagtg aaggacttct tagtaccggt gttaccagtt
    13021 tcttacccac aactttaaca gccacttatg agcaattgct tgcagtcact gaaaatcttg
    13081 gaaaccatta taaagaagca acaggtgcta agattcgtgg gatttattat gaaggtccat
    13141 atttcacaga aacttttaag ggggcacaaa atccaactta tatgagagac ccgggtgttg
    13201 aggagtttca ttcttggcaa aaagcggcaa atggcttgct taataaaatt gcccttgcac
    13261 cagaacgtga tggggtggaa gactttgttc gtacagttac gggcgaaggt gtgacggttg
    13321 ctcttggaca ttcaaacgcg acttttgatg aagccaaaaa agcagtcgat gctggagcga
    13381 gtgtttgggt gcatgcctac aatggaatgc gtgggttgac tcaccgtgaa ttggggatgg
    13441 ttggagccat gtaccaattg ccacatacct atgcagagtt gatctgtgat ggtcaccacg
    13501 tagatccaaa ggcttgcgaa attcttatca aacaaaaagg aacagaaaac atcgctctta
    13561 tcacagactg tatgacagct gggggattgg aagacggaga ttatatgttg ggagaattcc
    13621 cagttgtcgt tgcaaatgga actgcacgcc tcaaatcgac aggtaacttg gcaggttcta
    13681 tcctcaaact caaagatggt ttgaagaatg tggtcgaatg gggaattgcg aatccgcatg
    13741 aagcagtcat gatggccagc ttcaacccag ctaaatccgt tcacatcgat gacgtctgtg
    13801 gccaaatccg tgaaggctac gacgctgact tcatcgtatt agataaagat ttggaattgg
    13861 tagcaaccta cctagatggc gtaaaacgtt atcaagcata agagagaaag cagaagttag
    13921 agactaactt ctgctttttt atgcagggta ctttactggt aaataaaaag ttaaaaaaat
    13981 cacaaaaaaa gcttgaagaa acaaagaaaa aggcttacaa ttgaactata aatattacaa
    14041 ataaaaaaac ggaggagtgc tttatgaaag cctatactta tgttaaacca ggacttgctt
    14101 cttttgttga tgtagacaaa ccagttattc gcaagccaac agacgctatt gtgcgtattg
    14161 taaaaaccac tatttgtgga acagacctcc atattatcaa aggggatgtt cctacttgcc
    14221 aaagtggtac cattcttggc cacgaaggga ttgggattgt tgaagaagtt ggggaaggag
    14281 tttccaactt caaaaaaggt gacaaggtct tgatttcttg cgtctgtgcc tgtggtaaat
    14341 gctactactg taaaaaagga atttatgctc actgtgaaga cgaagggggc tggattttcg
    14401 gtcacttgat tgatggtatg caggctgaat atctacgtgt ccctcatgca gataatactc
    14461 tttaccatac tccagaagac ttgtcagatg aagctttggt tatgctgtca gacattctgc
    14521 ctactggata tgaaattggt gtcttaaaag ggaaagtaga acctggttgc agcgtagcca
    14581 ttattggttc aggtccagtt ggattggctg ctcttttaac agcccaattc tattcaccag
    14641 ctaaattgat tatggtagac ctagacgata accgcttgga aactgcccta tcattcggtg
    14701 cgactcataa ggttaattct tcagaccctg aaaaagccat taaagaaatt tatgatttga
    14761 cagatggtcg tggtgtggat gtcgctatcg aagctgttgg tattcctgca acatttgatt
    14821 tctgtcaaaa gattatcggt gtagacggaa cggttgccaa ctgtggtgtg catggtaaac
    14881 cagttgaatt cgatttagat aaactttgga ttcgcaacat caatgtaaca actggtttgg
    14941 tatctacaaa tacgactcca caattgttga aagcacttga aagtcataag attgaaccgg
    15001 aaaaattggt aactcactat ttcaaactca gtgaaattga aaaagcctac gaagtcttca
    15061 gtaaggcagc agaccaccat gccattaagg tcattatcga aaacgatatc tcagaagcct
    15121 aagtagtaaa aatatttttg tacataagta aatagaaatt cagtcatcca tcagatggct
    15181 ggatttttta tcaaaaaatt aagaaatgag catatttctt tccttgtctg gcggaattgg
    15241 ttataatata cggtacaaag gaatgaatga atatgtatcg tgttatagaa atgtacggag
    15301 attttgaacc gtggtggttc ttagaaggtt gggaagaaga tattgtagca agtagaaaat
    15361 ttgaccagta ttatgatgct ctcaaatact acaaaacttg ctggtttaga ttggaacaag
    15421 aatcgcctct ttataaaagt agaagcgact tgatgaccat tttttgggac ccggaagacc
    15481 aacgctggtg tgatgaatgt gatgagtatt tacaacaata ccattctttg gctcttttgc
    15541 aggatgagca ggttatccca gacgaaaaac tacgctcagg ctatgaaaaa caaaccagtc
    15601 aggaaaggaa tcgttcttgc cgtatgaaat taaaatagag aaaagtaact tttttggagt
    15661 tgcttttttt atttttctaa ctctttgcga atagtatagg tgaggaggta agtatggttc
    15721 aagaaattgc acaagaaatc attcgttcag ctcggaaaaa agggacgcag gatatctatt
    15781 ttgtccctaa gttagacgcc tatgagcttc atatgagggt aggagacgag cgctgtaaaa
    15841 ttggtagcta tgattttgaa aagtttgcag ccgttatcag tcactttaag tttgtggcgg
    15901 gtatgaatgt gggagaaaaa agacgtagtc aactgggttc ctgtgattat gcctatgacc
    15961 ataagatagc gtctctacgt ttatctactg taggcgatta tcgggggcat gagagtttgg
    16021 ttatccgttt gttgcacgat gaggagcagg acctgcattt ttggtttcag gatattgaag
    16081 aattaggcaa gcagtacagg caacggggac tctatctttt tgctggtccg gttgggagtg
    16141 gtaagacgac cttgatgcat gaattgtcca agtcactctt taaaggacag caagttatgt
    16201 ccatcgaaga tcctgtcgaa atcaagcagg acgacatgct tcagttgcag ttgaacgaag
    16261 caatcggcct aacctatgaa aatctaatca aactttcctt gcgtcatcga ccagatctct
    16321 tgattatcgg agaaattcgt gacagcgaga cggcgcgtgc agtggtcaga gctagtttga
    16381 caggtgcgac agtcttttca accattcacg ccaagagtat ccgaggtgtt tatgagcgtc
    16441 tgctggagtt gggtgtgagt gaagaagaat tggcagttgt tctgcaagga gtctgctacc
    16501 agagattaat cgggggagga ggaatcgttg actttgcaag cagagattat caagaacacc
    16561 aagcagccaa gtggaatgag caaattgacc agcttcttaa agatggacat atcacaagtc
    16621 ttcaggctga gacggaaaaa attagctaca gctaagcaaa aaaatatcat caccctattt
    16681 aacaatctct tttctagcgg ttttcatctg gtggagacta tctccttttt agataggagt
    16741 gctttgttgg acaagcagtg tgtgacccag atgcgtgtgg gcttgtctca ggggaaatca
    16801 ttctcagaaa tgatggaaag tttgggatgt tcaagtgcta ttgtcactca gttatcccta
    16861 gctgaagttc atggcaatct ccacctgagt ttgggaaaga tagaagaata tctggacaat
    16921 ctggctaagg tcaagaaaaa attgattgaa gtagcgacct atcccttgat tttgctgggt
    16981 tttcttctct taattatgct ggggctacgg aattacctgc tcccacaact ggatagtagc
    17041 aatattgcca cccaaattat cggtaatctg ccccaaattt ttctaggcat ggtagggctt
    17101 gtttccgtgc ttgccctttt agcactcact ttttataaaa gaagttctaa gatgagtgtc
    17161 ttttctatct tagcacgcct tccctttatt ggaatctttg tgcagaccta cttgacagcc
    17221 tattatgcac gtgaatgggg gaatatgatt tcacagggaa tggagttgac gcagattttt
    17281 caaatgatgc aggaacaagg ttcccagctc tttaaagaag tcggtcaaga tctggctcaa
    17341 accctgaaaa atggccgtga attttctcag acgataggaa cctatccttt ctttaggaag
    17401 gaattgagtc tcatcataga gtatggggaa gttaagtcca agctgggtag tgagttggaa
    17461 atctatgctg aaaaaacttg ggaagccttt tttacccgag tcaaccgcac catgaatttg
    17521 gtgcagccac tggtttttat ctttgtggca ctgattatcg ttttacttta tgcggcaatg
    17581 ctcatgccca tgtatcaaaa tatggaggta aatttttaaa atgaaaaaaa tgatgacatt
    17641 cttgaaaaaa gctaaggtta aagcttttac attggtggag atgttggtgg tcttgctgat
    17701 tatcagcgtg cttttcttgc tctttgtacc taatctgacc aagcaaaaag aagcagtcaa
    17761 tgacaaagga aaagcagctg ttgttaaggt ggtggaaagc caggcagaac tttatagctt
    17821 agaaaagaat gaagatgcta gcctaagaaa gttacaagca gatggacgca tcacggaaga
    17881 acaggctaaa gcttataaag aatacaatga taaaaatgga ggagcaaatc gtaaagtcaa
    17941 tgattaaggc ctttaccatg ctggaaagtc tcttggtttt gggacttgtg agtatccttg
    18001 ccttgggctt gtccggctct gtccagtcca ctttttcagc ggtagaggaa cagattttct
    18061 ttatggaatt tgaagaactc tatcgggaaa cccaaaaacg cagtgtagcc agtcagcaaa
    18121 agactagtct gaacttagat gggcagacga ttagcaatgg cagtcaaaag ttgccagtcc
    18181 ctaaaggaat tcaggtccca tcaggccaaa gtattacatt tgaccgtgct gggggcaatt
    18241 cgtccctggc taaggttgaa tttcagacca gtaaaggagc gattcgctat caattatatc
    18301 taggaaatgg aaaaattaaa cgcattaagg aaacaaaaaa ttagggcagt gattttactg
    18361 gaagcagtag tcgctctagc tatctttgcc agcattgcga ccctcctttt gggacaaatt
    18421 caaaaaaata ggcaagagga agcaaaaatc ttgcaaaagg aagaagtctt gagggtagct
    18481 aagatggcct tgcagacagg tcaaaatcag gtaaacataa acggagttga gattcaggtg
    18541 ttttctagcg aaaagggatt ggaggtctac catggttcag aacagttgtt ggcaatcaaa
    18601 gagccataag gtcaaggctt ttaccttgtt agaatccctg cttgccctgc ttgtcatcag
    18661 tgggggctta ctcctttttc aagctatgag tcagctcctc atttcagaag ttcgctacca
    18721 gcaacaaagc gagcaaaagg agtggatttt gtttgtggac caacttgagg cagaattaga
    18781 ccgttcgcag ttcgaaaaag tagaaggcaa tcgcctatac atgaagcaag atggcaagga
    18841 catcgccatc ggtaagtcaa agtcagacga ttttcgtaaa accgatgcta gtggacgggg
    18901 gtatcagcct atggtttatg gcctcaaatc agctcagatt acagaggaca atcaactggt
    18961 tcattttcgt ttccagtttc aaaaaggctt agaaagggag ttcatctatc gtgtggaaaa
    19021 agaagaaagt taaggcaggt gttctcctct acgcagtcac catagcagcc atctttagtc
    19081 ttttgttgca attttatttg aaccgacaaa tcgcccacta tcaagactat gctttaaata
    19141 aagaaaaatt ggttgctttt gccatggcta aacgaaccaa ggataaagcc gagcaagaaa
    19201 gtggggaaca ggtttttaat ctaggtcagg taagctatca aaacaagaaa acaagcttgg
    19261 tgacgactgt tcgtacgtct aagagccaat atgagtttct gtttccttca gtcaaaatca
    19321 aagaagagaa aagagataaa aaggaagagg tagcgaccga ttcaagcgaa aaagcggaga
    19381 aaaaaaatca gaagagaagc ctgaaaagaa agagaattcc tagtcaattc aactataatg
    19441 cgttgaatcc agaatagtcc actgtagttt ctagaaaatt gctggaaatg gatgttaagc
    19501 tccaattcat ttgtttatat cttatttcag tttactatac tttatgctaa attaaagata
    19561 tgaaacatga ttttaaccac aaagcagaaa ctttcgattc ccctaaaaat atcttcctcg
    19621 caaacttggt atgtcaagca gtcgagaaac agattgatat tttatcagac aaagaaattt
    19681 tagatttcgg tggtggcacg ggtctattag tcttgcccct agccaagcag gctaagtcag
    19741 tcactcttgt agacatttct gagaaaatgt tggagcaagc tcgtttgaaa gtggagcagc
    19801 aagcaatcaa gaatatccag tttttggagc aagatttacc gaaaaatccc ttggagaaag
    19861 agtttgattg ccttgctgtt agtcgggttc ttcatcatat gcctgatttg gatgcggctc
    19921 tctcactgtt tcatcaacat ttgaaggaag atgggaaact catcattgct gattttacca
    19981 agacagaagc taatcatcat ggatttgatt tagctgaact ggaaaacaag ctaattgagc
    20041 atggtttttc atctgtgcat agtcagattc tctatagcgc tgaagacctg tttcaaggaa
    20101 atcactcaga attcttttta acagtagccc aaaaatcact cgcctagtca gggagtgatt
    20161 tttctataag gatggaaaaa agaagggaaa tttggtaaga taggaatatg gattttgaaa
    20221 aaattgaaca agcctatacc tatttactag agaatgtcca agtcatccaa agtgatttgg
    20281 cgaccaactt ttatgacgcc ttggtggagc aaaacagcat ctatctggat ggtgaaactg
    20341 agctaaacca ggtcaaagac aacaatcagg cccttaagcg tttagcacta cgcaaagaag
    20401 aatggctcaa gacctaccag tttctcttga tgaaggctgg gcaaacagaa cccttgcagg
    20461 ccaatcacca gtttacacca gatgccattg ctttgctttt ggtgtttatt gtggaagagt
    20521 tgtttaaaga ggaggaaatt actatcctcg aaatggggtc tgggatggga attctaggcg
    20581 ctactttctt gacctcgctt gataaaaagg tggattactt gggaatggaa atggatgatt
    20641 tgctgattga tctggcagct agcatggcag atgtaattgg tttgcaggct ggctttgtcc
    20701 aaggagatgc cgttcgtcca caaatgctca aagaaagcga tgtggtcatc agtgacttgc
    20761 ctgttggcta ttatcctgat gatgccgttg cgtcgcgcca tcaagttgct tctagccaag
    20821 aacatactta cgcccatcac ttgctcatgg aacaagggct taagtacctc aagtcagacg
    20881 gatacgctat ttttctagct ccgagtgatt tgttgaccag tcctcaaagt gatttgttaa
    20941 aagaatggct gaaagaagag gcgagtctgg ttgctatgat tagtctgcct gaaaatctct
    21001 ttgctaatac caaacaatct aagactattt ttatcttaca gaagaaaaat gaaatagcag
    21061 tagatccttt tgtttatcca cttgctagct tgcaagatgc aagtgtttta atgaaattta
    21121 aagaaaattt tcaaaaatgg actcaaggta ctgaaatata aaatagattt tgttataata
    21181 gttgaaaacg cttaaaaagg ggtatcatgt tatgataaaa acaattgcaa tcaatgcagg
    21241 aagttcaagt ttgaaatggc aattatactt aatgccagaa gaaaaagtat tggcgaaagg
    21301 tttgattgaa cgtatcggtt tgaaagattc aatttcaact gtaaaatttg acggccgttc
    21361 tgagcaacaa attttggata ttgaaaatca tacacaagcc gttaaaattt tattggatga
    21421 cttgattcgt ttcgatatta tcaaggctta tgacgagatt acaggtgttg gacatcgtgt
    21481 tgttgctggt ggagaatatt tcaaagaatc aacagttgtt gagggagatg ttttagaaaa
    21541 agttgaagag ttgagtttgt tggctcctct acacaacccg gccaatgcag caggtgttcg
    21601 tgccttcaag gaattgttgc cagacattac cagtgtagtt gtttttgata cttccttcca
    21661 cacaagtatg ccagagaaag cttatcgcta ccctctacca acaaaatatt acacagaaaa
    21721 caaggttcgt aaatacggtg ctcatggtac aagtcaccag tttgtagcag gagaggctgc
    21781 aaaactcttg ggacgtccat tagaagactt gaagttaatt acctgtcata ttggtaacgg
    21841 aggctcaatt acagctgtga aagccggcaa atctgtagac acttctatgg ggttcactcc
    21901 tcttggtggt attatgatgg gaacgcgtac aggggatatt gatccagcta tcattcctta
    21961 tttaatgcaa tatacagagg attttaacac accagaagat atcagtcgtg ttcttaaccg
    22021 tgaatcaggt cttttgggag tttctgctaa ttctagcgat atgcgcgata tagaagcagc
    22081 tgtagcagaa gggaatcacg aggctagctt ggcttatgaa atgtatgttg accgtatcca
    22141 aaaatatatc ggtcagtacc ttgcagtgct aaatggagca gatgccattg ttttcacagc
    22201 aggtgtcggt gaaaatgcag agaatttccg tcgtgatgta atctcaggga tttcgtggtt
    22261 tggttgtgat gttgatgatg aaaagaatgt ctttggcgtt acaggagaca tctcaacaga
    22321 ggcagctaaa atccgtgtct tggttattcc aacagatgaa gaattagtca ttgcccgtga
    22381 cgttgaacgc ttgaaaaaat aagtgaaact aaaaaaatat tcaatacaag gagttgggaa
    22441 agttattttt ccagcttctt tttctgatga aattgtccaa aaccttgcta tgattggctt
    22501 ttttgaaaaa tatggtataa tagtagtaat ttaatagatg gagttgagtt ttgaagaaaa
    22561 actttcgtgt aaaaagagag aaagatttta aggcgatttt caaggagggg acaagttttg
    22621 ctaatcgcaa atttgtggtc taccaattag aaaaccagaa aaaccatttt cgagtaggtc
    22681 tatcagttag caaaaaactg gggaatgccg tcactagaaa tcaaattaag cgacggattc
    22741 ggcatattat ccagaatgca aaagggagtc tggtagaaga tgtcgacttt gttgtcattg
    22801 ctcgaaaagg agtcgaaacc ttgggatacg cagagatgga gaaaaatcta ctccatgtat
    22861 taaaattatc aaagatttac cgggaaggaa atgggagtga aaaagaaact aaagttgact
    22921 agtttgctag gactgtctct gttaatcatg acagcctgtg cgactaatgg ggtaactagc
    22981 gatattacag ccgaatcggc tgatttttgg agtaaattgg tttacttctt tgcggaaatc
    23041 attcgctttt tatcgtttga tattagtatc ggagtgggga ttattctctt tacggtcttg
    23101 attcgtacag tcctcttgcc agtctttcag gtgcaaatgg tggcttctag gaaaatgcag
    23161 gaagctcagc cacgcattaa ggcgcttcga gaacaatatt caggtcgaga tatggaaagc
    23221 agaaccaaac tagagcagga aatgcgtaaa gtatttaaag aaatgggtgt cagacagtca
    23281 gactctcttt ggccgatttt gattcagatg ccggttattt tggccctgtt ccaagcccta
    23341 tcaagagttg actttttaaa gacaggtcat ttcttatgga ttaaccttgg tagtgtggat
    23401 acaacccttg ttcttccgat tttagcagca gtattcacct ttttaagtac ttggttgtcc
    23461 aacaaagctt tgtctgagcg aaatggcgct acgactgcga tgatgtatgg gattccagtc
    23521 ttgattttta tctttgcagt ttatgcgcca ggtggagtcg ccctatactg gacagtgtct
    23581 aatgcttatc aagtcttgca aacctatttc ttgaataatc cattcaagat tatcgcagag
    23641 cgcgaggccg tagtacaggc acaaaaagat ttggaaaata gaaaaagaaa agccaagaaa
    23701 aaggctcaga aaacgaaata aataaggagg aatctggtaa tggtagtatt tacaggttca
    23761 actgttgaag aagcaatcca gaaaggattg aaagaattag atattccaag aatgaaggct
    23821 catatcaaag tcatttctag ggagaaaaaa ggctttcttg gtctatttgg taaaaaacca
    23881 gcccaagtgg atattgaagc gattagtgaa acgactgttg tcaaagcaaa tcaacaggta
    23941 gtaaaaggcg ttccgaaaaa aatcaatgat ttgaacgagc ctgtgaagac ggttagtgaa
    24001 gaaaccgttg accttggtca tgtggttgat gctattaaaa aaatagagga agaaggtcaa
    24061 ggtatttctg atgaagtcaa ggctgaaatc ttaaaacatg aaagatatgc cagcactatc
    24121 ttagaagaaa ctggtcacat tgagatttta aatgaacttc aaatcgagga agcgatgagg
    24181 gaagaagcag gcgctgatga ccttgaaact gagcaagatc aaactgaaaa tcaagacttg
    24241 aaagagatgg gcttgaaggt cgagcaaagt tatgatattg cccaggtggc tacggatgtg
    24301 actgcttatg ttcaaacgat tattgatgac atggatgttg aggctacact ttcaaatgat
    24361 tataaccgtc gtagcatcaa tttgcaaatt gatactaacg aaccaggtcg tattatcggc
    24421 taccatggta aagtcttgaa ggccttgcaa ctgttggctc aaaattatct ttacaactgc
    24481 tattcaagaa ccttctatat cactattaat gtcaatgatt atgttgaaca ccgtgcagaa
    24541 gtcttgcaga cctatgcgca aaaattggcg attcgtgttt tagaagaagg acgtagtcat
    24601 caaacagatc caatgtcgaa tagtgaacgc aagattatcc accgtattat ttcacgtatg
    24661 gatggcgtga ccagttactc tgaaggtgat gagccaaatc gctatgtcgt tgtagataca
    24721 gaataagtaa aatcagggtt gacctgattt tttgctagct agaggaggtt aaactgatgt
    24781 tgaataagat aagagactat ctagactttt ctggtttgca gtaccgtagt cctgataaag
    24841 cgggagcaga gcgagagaag atgctggcgt tccgccacaa aggacaagag gcccgaaagg
    24901 cttttacaga actggccaaa gcctttcaag caagccatcc agaatggcaa ctccaacaga
    24961 ctagtcagtg gatgaatcag gcccagcgtt tgagaccaca tttttgggtt tatctacaga
    25021 gagacggaca agtgacagaa cctatgatgg ccttacgttt gtatgggaca tctactgact
    25081 ttggaatttc tttggaagtc agtttcatcg aacgtaagaa ggatgagcaa acactgggca
    25141 agcaggccaa agttttagac attccaaccg ttaaagggat ttattatcta acctactcta
    25201 atggtcaaag tcaacggtgg gaggcgaatg aagaaaagcg tcgtacttta cgcgagaagg
    25261 tgagaagtca agaagttcga aaagttttag tgaaggtaga tgttcctatg acagaaaatt
    25321 cgtctgaaga agaaatcgta gaaggcttat tgaagtctta ttctaaaatt cttccctatt
    25381 atctagctac gagaaaataa gataatttgt aaaacatcat aaatcataca gtccaagagt
    25441 gaacagtccg ctgtgtaatt cttggtcttt ttgtttgcgc tttcgcatta tataataaac
    25501 ttacaaaaac aattcaaaag gagaacaatt atggaagtcg tttcaagtgt tctaaattgg
    25561 ttttctagca atattttgca gaatcccgca tttttcgtag gtttattggt gttgatagga
    25621 tatgcacttt tgaaaaaacc tgcccatgac gttttttcag ggtttgttaa agcaacagta
    25681 gggtatatgt tgcttaacgt gggtgctggt ggtttggtta caacctttcg tccaatctta
    25741 gcagctctta actacaaatt ccaaattggt gcagcggtta tcgaccctta ttttagactt
    25801 gctgcagcaa acaacaaaat tgtagcagag tttccagatt ttgttggaac tgcaactaca
    25861 gctctattga ttggttttgg aataaatatc ttgctcgtag ctcttcgaaa gattacgaag
    25921 gtaagaaccc tctttattac tggtcacatc atggtacaac aagctgcaac agtatctctt
    25981 atggttctat tcttagtacc acaattgcgc aatgcttacg gtacagcagc gattggtatc
    26041 atctgtggac tttactgggc agttagttca aatatgactg ttgaggcaac tcaacgcttg
    26101 actggtggtg gcggatttgc gattggtcac caacagcaat ttgcaatctg gtttgtagat
    26161 aaagtagcag gacgctttgg taagaaagaa gaaagtttag acaatcttaa attacctaag
    26221 ttcctctcaa tcttccacga tacagttgtt gcatctgcta ccttgatgct cgtattcttc
    26281 ggagccattc ttttaatctt gggtccagac attatgtcta ataaagaagt catcacttca
    26341 ggaactctat tcaatcctgc taaacaagat ttctttatgt acattatcca aacagccttt
    26401 accttctcag tttacttgtt cgttttgatg caaggtgtcc gaatgttcgt atctgagttg
    26461 acaaacgcct tccaaggtat ttcaaacaaa ttgttgccag gttcattccc agcggttgac
    26521 gttgcagctt cttatggatt tggttctcca aatgctgtct tgtcaggatt tacctttggt
    26581 ttgattggtc aattgattac aattgttttg ctcatcgtct ttaaaaatcc gattcttatt
    26641 attacaggat ttgtaccagt gttctttgac aatgcagcca ttgcggtcta cgctgataaa
    26701 cgcggcggat ggaaagcggc tgttatcctt tcctttatat caggtgtcct tcaagttgct
    26761 ctaggagctc tttgtgtggc ccttctcgat ttggcatctt atggtggcta ccatggaaat
    26821 atcgactttg aattcccatg gcttggattt ggatatatct tcaaatacct tggtattgtt
    26881 ggttatgtac ttgtgtgtct cttcttgctt gttattcctc aacttcaatt tgccaaagca
    26941 aaagataaag agaaatatta caacggtgaa gttcaagaag aagcttagta tctagaaaag
    27001 gagaaataaa atggttaaag tattagcagc gtgcggaaat ggaatgggtt catcaatggt
    27061 tatcaagatg aaggttgaaa atgctctccg taagcttaat caaacagatt ttacagtcaa
    27121 ttcatgcagt gtcggtgaag ctaaaggttt agcagtagga tatgacattg taatcgcttc
    27181 tcttcatttg attcaagaat tggaagggcg aactaatggg aagttaattg ggcttgataa
    27241 cttgatggat gataaagaaa tcaccgaaaa actcagtcaa gcactacagt aaaaggttgg
    27301 agggggctgg acagaaactg agagttatcg tttctgtcca gccccctctt taaataaagg
    27361 aggcagatat gaatttaaaa caagctttaa ttgacaatga ctcgatccga ctaggtttag
    27421 aggctaacga ttggaaagaa gcagtcaagg tagcagtaga tcccttgatt gaaagtgggg
    27481 caattttgcc agagtattac gatgctatca ttgaatcgac tgaagagtat gggccttact
    27541 atatcttgat gccaggtatg gctatgcccc acgctagacc tgaagctggt gtgcaaagtg
    27601 atgccttttc attgattacc ttacaaaatc ctgttgtatt ttcagatggg aaagaggtat
    27661 ctgttttgtt ggcactagca gcaacaagtt caaaaattca cacaagtgta gccattccac
    27721 aaattattgc cctgtttgaa ttagaagatt ctattgcacg tttacaggct tgccagacta
    27781 aagaagatgt cttggctatg attgaagaat ctaaggatag cccttatctc gaaggattgg
    27841 atttggaaag ttagaaagag gaataaagaa atgacaaaaa gaatacctaa tttacaagtt
    27901 gcattagacc attcagactt gcaaggagcg attaaagcag ctgtttctgt tggtcaggaa
    27961 gtagatatta tcgaagctgg aactgtttgc ttgcttcaag ttggaagtga actggctgaa
    28021 gtcttgcgta gccttttccc agataagatt attgtggcag acacaaaatg tgctgatgct
    28081 ggtggaacag ttgctaaaaa taatgcggtt cgtggagcag actggatgac ttgtatctgt
    28141 tgtgcaacca tccctactat ggaagcagct ctaaaggcta tcaagactga acgaggagaa
    28201 cgaggtgaaa tccagatcga gctttatggc gattggactt ttgaacaagc tcagctttgg
    28261 ctagatgcag gtatctcaca agctatttat caccaatctc gtgatgctct tcttgctggt
    28321 gaaacttggg gtgaaaaaga ccttaataag gttaaaaaac tcattgacat gggcttccgt
    28381 gtatctgtaa caggtggtct agatgtagat actctcaaac tctttgaagg tgttgatgtc
    28441 tttaccttta tcgcaggtcg tggaattaca gaggctgcgg atccagcagg agcagcgcgt
    28501 gccttcaagg atgaaatcaa acgaatttgg gggtaaatca tggtacgtcc aattggaatt
    28561 tatgaaaagg caaccccaac acactttact tggctagaac gtttaaattt tgccaaggag
    28621 ttaggctttg attttgtcga gatgtctatt gacgaacgtg acgagcgttt agcaagactt
    28681 gactggagta aggaagaacg cttggaagtt gtcaaagcaa tctatgaaac tggtgttcgt
    28741 attccttcta tctgtttttc aggccatcgt cgctacccat tgggttcaaa agatccagtt
    28801 ctagaggaaa aatctctaga actcatgaaa aaatgtatcg aattagctca agacttggga
    28861 gttcgtacga ttcaattagc tggttacgat gtttactatg aggaaaagtc accccagaca
    28921 cgccaacgtt ttatcaaaaa tttgagaaaa gcctgtgact gggctgaaga agctcaggtg
    28981 gtacttgcta ttgaaattat ggatgatcct ttcatcagta gcatcgaaaa atatttggct
    29041 atagaaaaag agattgactc tcccttcctc tttgtatatc cagatattgg taatgtgtct
    29101 gcatggcata atgatatcta tagtgagttt tatcttggtc atcatgccat cgcagctctc
    29161 catctcaagg atacttatgc agtgacagaa agttcaaagg gccagttccg agatgtacct
    29221 ttcgggcaag gttgtgttaa atgggaagaa gctttcgata ttttaaagga aaccaattat
    29281 aatggacctt tcctaatcga aatgtggtct gaaaattgtg aaacagtaga agaaacacgc
    29341 gcagccgttc aagaggcgca agcttttctc tatccactca ttaagaaagc aggtttgatg
    29401 taagatgaat caagtaatca atgctatgcg taaacgagtc tgtgatgcca atcaatcatt
    29461 gccaaaacat ggacttgtca aatttacctg ggggaatgta tctgaagtta atcgcgaact
    29521 cggtgtcatt gttatcaaac catcaggcgt ggattatgac gaattgacac ctgaaaacat
    29581 ggtagtgact gatctagatg gtaagatcct agaaggggat ttaagaccat cttccgacct
    29641 cccaactcat gtgcaattat ataaggcttg gtcagaaatt ggtagtgtgg ttcacaccca
    29701 ttcgacagaa gctgttggtt gggctcaggc aggtcgtgat attcctttct acggaacaac
    29761 ccatgcagat tatttctacg gttcaatccc ttgcgcccgt agtttgacca aggacgaagt
    29821 agaagtggcc tatgaaaaag atactggcct ggttatcgta gaagagtttg aacatcgcgg
    29881 acttaacccg gttgaagtac caggaattgt tgtacgcaat cacggtccat tcacctgggg
    29941 caaaaatcca gagaatgctg tttatcactc tgtcgtacta gaggaagtat caaagatgaa
    30001 tcgatttaca gaacaaatca atccaagagt tggacctgct ccccagtaca tactagaaaa
    30061 acactaccaa cgtaaacatg gaccaaatgc ttattatggt caaaagtaag aacgatgaag
    30121 gaggagaaaa agataaattt agctcctctt tttacatttg atttttattg agagtaaagt
    30181 tggaattgaa gtaattttaa aagatttttt agaaatagcg cttgatatat atatatggta
    30241 aaataaaaag aattgctgtg atatcaatag atttggggga ttttttaata tggtactgga
    30301 taaggcaagt tgtgatttgc ttcaatattt gatggatcaa gaaacgtcca aaacgattat
    30361 ggcgatttcg aaagatttga aagagtcaag aaggaaaatt tattatcaca ttgacaaaat
    30421 caatgctgct ctggttgacg aggcgcttca catcattagt attccacgaa ttggtattca
    30481 cttaacggaa gagcagagag atgcttgttg taaactatta tcggaagtag attcgtacga
    30541 ttatatcatg agtgcgcatg aacgtatgat gataatgtta ctatggatag gtatttctaa
    30601 agaacgtatt acgattgaaa aattgataga gttaacagag gtatctagga atactgttct
    30661 caatgatttg aatagtattc gttatcaact aactttggaa caatatcagg tgatcttgca
    30721 agtgagcaag tcacagggat accaccttca tgcccaccct cttaataaaa ttcagtatct
    30781 tcaatcgctt ctatatcata tttttatgga agaaaatgcc acttttgtat ctattttaga
    30841 agataagatg aaagagaggt tagatgatga gtgtttgctt tctgttgaaa tgaaccaatt
    30901 ttttaaggaa caggttcctt tagttgaaca agatttaggg aagaaaataa accatcatga
    30961 aataactttt atgttgcagg ttctacctta tttgctgtta agctgtcata atgttgaaca
    31021 gtatcaagaa agacatcagg atatagagaa agaattttct ttgataagaa aaagaataga
    31081 gtatcaggtg tctaagaaat taggagaacg gttgtttcaa aagtttgaaa tttctttgtc
    31141 aggacttgaa gtttctcttg tagctgttct cctcctctcc tatcgtaaag atttggatat
    31201 tcatgcagaa agtgatgatt ttcggcaatt aaaacttgct ttagaagaat ttatctggta
    31261 ttttgaatca caaatccgaa tggagattga gaacaaggat gatttgttac gaaatttgat
    31321 gatccactgt aaagccttgt tatttagaaa gacttacggt attttttcta aaaatcctct
    31381 aacaaaacaa attcgatcca agtatggaga attattttta gtcactagaa aatctgcgga
    31441 aattttagaa ggagcatggt ttattcggct aacagacgat gatattgcct atttgacgat
    31501 tcatattgga ggatttttaa agtatacacc atcgtctcaa aaaaatatga aaaaagttta
    31561 tctcgtttgt gatgaaggtg ttgcggtttc gagacttttg ctgaaacaat gcaaacttta
    31621 ttttccaaat gagcaaattg acactgtatt tacaacagaa caatttaaga gtgtggaaga
    31681 tattgcacaa gttgatgtag tgattactac taatgatgat ttggatagca gatttccgat
    31741 tttaagggtt aatcctatcc ttgaagcaga agatattttg aaaatgctag actatcttaa
    31801 acacaatata tttcgtaatg agagcaaaag tttcagtgaa aatctttcta gtcttatttc
    31861 gtcttatatt gtagatagca agttggctag taagttccaa gaagaggttc aaacacttat
    31921 aaatcaagaa atagtagttc aagctttttt ggaagatatt tgaaggacag tccaatgatg
    31981 aacacaaacc tgtgtttttc ttggtctttt ttagtgtttt gaagggtggt atactaatct
    32041 caaagataac aattatatcc aaaggaggca acatatgcca aacgtcaaag aaattacaag
    32101 agagtcatgg attttagcca ctttcccaga gtggggaaca tggttgaacg aagaaatcga
    32161 agaagaagtc gtacctgaag gcaactttgc catgtggtgg ctaggcaact gtggtacttg
    32221 gattaagaca ccagctggtg ctaacgttgt catggacctt tggtcaaacc gtggaaaatc
    32281 aaccaaaaaa gtgaaagata tggttcgtgg gcaccaaatg gcaaatatgg caggtgttcg
    32341 taagttgcaa ccaaacttgc gtgttcagcc aatggttatc gatccatttg ctatcaacga
    32401 actagactat tacttagttt cacacttcca cagtgatcat atcgacccat acacagctgc
    32461 agcaattctc aacaatccta agttagagca tgttaagttt atcggtcctt accactgtgg
    32521 acgaatctgg gaaggatggg gtgttccaaa agaacgtatc atcgttgtta aaccaggtga
    32581 cactatcgaa ttaaaagata tgaagattca tgcagtagaa tcatttgacc gtacttgctt
    32641 ggtaactctc ccagtgaacg gtgctgatga gacaggcggt gaacttgctg gcttggctgt
    32701 tacagatgaa gaaatggctc aaaaggctgt taactatatc tttgaaacac caggtggaac
    32761 catctatcat ggtgcagatt ctcacttctc aaactatttt gcaaaacatg gtaaagactt
    32821 taaaattgat gttgctttga ataactatgg tgaaaatccg gtaggtatcc aagacaaaat
    32881 gacatctatc gaccttcttc gtatggcaga aaatctgcgt accaaagtca ttatcccagt
    32941 tcactatgat atctggtcta acttcatggc ttctactaat gagattctag aactttggaa
    33001 aatgcgaaaa gatcgcttgc aatacgattt ccatccattt atctgggaag ttggcggtaa
    33061 gtacacttat cctcaagatc aacacttagt agaataccat catccacgtg gttttgatga
    33121 ttgttttgaa caagactcta acattcaatt taaagctttg ctataatata aaaatattct
    33181 ttggaggtta tccgtatgtt gcatgatacg gataattttc atataatagt aaaatagaat
    33241 gtgtgattca ataatcacct caaatagaaa ggaaattcta tgtcaaatct atctgttaat
    33301 gcaattcgtt ttctaggtat tgacgccatt aataaagcca actcaggtca tccaggtgtg
    33361 gttatgggag cggctccgat ggcttacagc ctctttacaa aacaacttca tatcaatcca
    33421 gctcaaccaa actggattaa ccgcgaccgc tttattcttt cagcaggtca tggttcaatg
    33481 ctcctttatg ctcttcttca cctttctggt tttgaagatg tcagcatgga tgagattaag
    33541 agtttccgtc aatggggttc aaaaacacca ggtcacccag aatttggtca tacggcaggg
    33601 attgatgcta cgacaggtcc tctagggcaa gggatttcaa ctgctactgg ttttgcccaa
    33661 gcagaacgtt tcttggcagc caaatataac cgtgaaggct acaatatctt tgaccactat
    33721 acttacgtta tctgtggaga cggagacttg atggaaggtg tctcaagcga ggcagcttca
    33781 tacgcaggtt tgcaaaaact tgataagttg gttgttcttt atgattcaaa tgatatcaac
    33841 ttggatggtg agacaaagga ttcctttaca gaaagtgttc gtgaccgtta caatgcctac
    33901 ggttggcata ctgccttggt tgaaaatgga acagacttgg aagccatcca tgctgctatc
    33961 gaaacagcaa aagcttcagg caagccatct ttgattgaag tgaagacggt tattggatac
    34021 ggttctccaa acaaacaagg aactaatgct gtacacggcg cccctcttgg agcagatgaa
    34081 actgcatcaa ctcgtcaagc cctcggttgg gactacgaac catttgaaat tccagaacaa
    34141 gtatatgctg atttcaaaga acatgttgca gaccgtggcg catcagctta tcaagcttgg
    34201 actaaattag ttgcagatta taaagaagct catccagaac tggctgcaga agtagaagcc
    34261 atcatcgacg gacgtgatcc agtcgaagtg actccagcag acttcccagc tttagaaaat
    34321 ggtttttctc aagcaactcg taattcaagt caagatgcct tgaatgttgt ggcagctaaa
    34381 ttaccaacct tcctaggtgg atcagctgac cttgctcact caaacatgac ttatatcaag
    34441 acggatggac ttcaagacga taccaatcgc ttgaatcgta acattcagtt tggtgttcgt
    34501 gaatttgcaa tgggaacaat cttgaacggg atggcccttc atggtggact tcgtgtatac
    34561 ggtggaactt tcttcgtctt ctctgactat gtgaaggcag ctgtccgctt gtcagcctta
    34621 caaggacttc ctgtgactta tgtctttacc catgattcaa tcgcagttgg ggaagatggt
    34681 ccgactcacg aaccagttga gcatttagca ggtcttcgtg ctatgccaaa tctaaatgtt
    34741 ttccgtccag cagatgcgcg tgaaacgcaa gcagcttggt accttgcagt gacaagtgag
    34801 aaaacaccaa ctgcccttgt cttgacacgt caaaacttga ctgttgaaga tggaacagac
    34861 ttcgacaagg ttgctaaagg tgcttatgtt gtatatgaaa atgcagccga ctttgatacc
    34921 atcttgattg cgacaggttc agaggttaat cttgctgtct cagctgctaa agaattggct
    34981 agtcaaggcg aaaaaatccg cgtagtcagc atgccatcta cagatgtctt tgataaacaa
    35041 gatgcagctt acaaggaaga gattcttcca aatgcagtcc gccgtcgtgt tgcagtcgaa
    35101 atgggtgcaa gtcaaaactg gtacaaatat gttggtctcg atggtgccgt tctaggtatt
    35161 gataccttcg gagcctctgc cccagcacca aaagtattgg cagaatatgg ctttactgta
    35221 gaaaatcttg taaaagttgt tcgaaacttg aaataatcct aaaaatcagg gcgtaagctc
    35281 tggtttttct taccagaaaa gtaaggtaca atcttgtaaa agtagctgaa atttgatata
    35341 gtagtcctat gtaaaagaca aaggagaaaa caatgaatcc aaatattact tttttaatca
    35401 tgcttgtagg tatgatggcc ttgatgttct ttatgcaacg ttctcaaaag aaacaagctc
    35461 aaaagcgtat ggaaagctta aataaactac aaaaaggcta tgaagtgatt acaatcggtg
    35521 gactttatgg aacagtcgat gaagtagata cggagaaggg aacaatagtt cttgacgtag
    35581 atggagttta cttgactttt gaactagctg ctatcaagac agtattaccg ctgaaagaaa
    35641 cagcttcact agaaggcgca attgaaaaat aagacgggat cacgaactcc cgtttttcta
    35701 taaaagaaag gaaatgggat gaaaaaatta gtctttgtct gtctgggaaa tatttgccgt
    35761 agccctatgg ccgagtttgt tatgaaatca atgacagata actacgaaat ccaaagtcga
    35821 gcaacttcct cttgggaaca tggcaatccg attcataagg ggactcaggg aatttttcaa
    35881 gagtatgaga ttccttatga caagaacaag acatcgcttc agattagtaa ggaagatttt
    35941 gaagcctttg attatattat cggaatggac gcttcaaata tttctgactt acgtcagatg
    36001 tgtccagtag actgtcaaga taagatttac tcattttcat ctgaaagtgt tccagaccct
    36061 tggtatacag gagattttga agaaacctat cgacgtgttc aagagggctg tcaagcttgg
    36121 ttagaacgtt tagaaaagga gagttaaggt ggaaaatctt acgaattttt acgaaaagta
    36181 tcgtgtctat ctgactcgtc cacgattaga gcttttggca gtagttacca ttgttttctg
    36241 tgctgtactc gtcttttttc taaatattcc aggaaaaggt gtcttaaaac tcgataatgg
    36301 aacgattgtt tatgatggca gtcttgtccg tggtaaaatg aatggtcaag gtaccattac
    36361 cttccaaaat ggagaccaat atacaggtgg cttcaacaat ggagccttca acggaaaagg
    36421 tacctttcaa tctaaagaag gctggaccta cgaaggtgat tttgtaaatg gtcaggctga
    36481 aggaaaaggg aaactaacaa cagaacaaga agtcgtttat gaaggaactt ttaaacaagg
    36541 cgtttttcaa caaaaataaa gcctccttat caaaggaggt attattagaa ttacaaggta
    36601 agcgcttacc tgtaaatccc tttctttcca aatccctctt ccaagcaagt ttgtgaaata
    36661 aaaaatattt gaaataaatt tcacaaactt caaagataaa acctgataag aaaagaaaat
    36721 gagaaaagtt tcacaagagt ttaaaaattc tttgtgaaat gtttatgaaa ctgtttacaa
    36781 agttgaaata atacgttata ataaacttgt gaaaaaatta acaaaggata tcgatccttg
    36841 aaagctatgg aggaaaatat ggctgataaa aaaactgtga caccagagga aaagaaactc
    36901 gttgctgaaa aacacgtaga tgagttggtt caaaaagctc tagttgccct tgaagaaatg
    36961 cgtaaattgg atcaagagca agttgactac atcgttgcca aagcatcagt agcagctttg
    37021 gatgcccacg gagaattggc tttacatgcc tttgaagaaa caggacgtgg tgtatttgaa
    37081 gataaagcaa ctaagaactt gtttgcctgt gaacacgtag taaacaacat gcgtcacact
    37141 aagacagttg gcgttatcga agaagacgat gtaacaggat tgactcttat tgctgaacca
    37201 gttggtgttg tttgtggtat tactccaaca acaaacccaa catcaacagc aatcttcaaa
    37261 tcattgattt cattgaagac acgtaaccca atcgtctttg ccttccatcc atcagcacaa
    37321 gaatcatctg ctcatgcagc tcgtatcgtc cgcgatgcag ctatcgcagc tggtgctcct
    37381 gaaaactgtg tgcaatggat tactcaacca tctatggaag caacaagtgc ccttatgaac
    37441 cacgaaggtg ttgcgacaat ccttgcaaca ggtggtaatg ccatggttaa ggcggcttat
    37501 tcatgtggta aaccagctct tggggtaggt gccggaaacg ttccagctta tgttgaaaaa
    37561 tcagcaaaca ttcgtcaagc agcacacgat atcgtcatgt ctaaatcatt tgataacggt
    37621 atggtctgtg catctgaaca agcagttatc attgataaag aaatttacga tgaatttgta
    37681 gcagagttca aatcttacca cacttacttt gtaaacaaaa aagaaaaagc tcttcttgaa
    37741 gagttctgct tcggcgtcaa agcaaacagc aaaaactgtg ctggtgcaaa attgaacgct
    37801 gacatcgttg gtaaaccagc aacttggatt gcagaacaag caggatttac agttccagaa
    37861 ggaacaaaca ttcttgctgc agaatgtaaa gaagttggcg aaaatgagcc attgactcgt
    37921 gaaaaattgt caccagttat tgcagttttg aaatctgaaa gccgtgaaga tggtattact
    37981 aaggctcgtc aaatggttga atttaacggt cttggacact cagcagctat ccacacagct
    38041 gacgaagaat tgactaaaga atttggtaaa gctgttaaag ctattcgtgt tatctgtaac
    38101 tcaccttcta cttttggtgg tatcggggac gtttacaatg ccttcttgcc atcattgaca
    38161 cttggatgtg gttcttacgg acgcaactca gttggggata acgttagtgc cattaacctc
    38221 ttgaatatca aaaaagtcgg aagacggaga aataacatgc aatggatgaa acttccttca
    38281 aaaacatact ttgaacgtga ttcaattcaa taccttcaaa aatgtcgtga cgttgaacgt
    38341 gtcatgatcg ttactgacca tgccatggta gagcttggtt tccttgatcg tatcatcgaa
    38401 caactggacc ttcgtcgcaa taaggttgtt taccaaatct ttgcggatgt agaaccggat
    38461 ccagatatca caactgtaaa ccgtggtact gagattatgc gtgccttcaa accagatacc
    38521 atcatcgcac tcggtggtgg gtctccaatg gatgctgcca aagtaatgtg gctcttctac
    38581 gagcaaccag aagtggactt ccgtgacctt gtccaaaaat tcatggatat ccgtaaacgt
    38641 gccttcaagt tcccattgct tggtaagaag actaaattca tcgcgattcc aactacatct
    38701 ggtacaggat ctgaagtaac accatttgcc gttatctctg ataaagcaaa caaccgtaaa
    38761 tacccaatcg ctgactactc attgacacca actgtggcaa tcgtagatcc tgctttggta
    38821 ttgacagttc caggatttgt tgctgctgat actggtatgg acgtattgac tcacgcgaca
    38881 gaagcatacg tatcacaaat ggctagtgac tacactgatg gtttagcact tcaagccatt
    38941 aaattggtct ttgaaaatct cgaaagctca gttaagaatg cagacttcca ctcacgtgag
    39001 aaaatgcata acgcttcaac aatcgctggt atggcctttg ccaatgcctt cctaggtatt
    39061 tctcactcaa tggcccataa gattggtgcg caattccaca caatccacgg tcgtacaaat
    39121 gctatcttgc ttccatacgt tatccgttac aacggtacac gtccagctaa gacagcaaca
    39181 tggcctaagt acaactacta ccgtgcagat gaaaaatacc aagatatcgc acgcatgctt
    39241 ggacttccag cttctactcc agaagaaggg gttgaatctt acgcaaaagc tgtctacgaa
    39301 ctcggtgaac gtattgggat ccaaatgaat tttagagacc aaggaattga cgaaaaagaa
    39361 tggaaagaac attctcgtga attagccttc ctggcttatg aagaccaatg ttcaccagct
    39421 aacccacgtc ttccaatggt agaccatatg caagaaatca tcgaagatgc atactatggc
    39481 tacaaagaaa gaccaggacg ccgtaaataa ttgtttatca gtctagaagc aagacaaaaa
    39541 ctcaatttga gggaaagatc cagtaatttt tctatgataa aaggcatcct atcaaggttt
    39601 ttgaacacct gataggatgc ctttttatga tattgaggcc tttttgccct ttttgaaaaa
    39661 ctagaataga aacaaaatat ataatagatt gaaactggaa tagtacactt ctgcttctaa
    39721 aacattgtta gaattcga
//
LOCUS       DBEJAU010000012        38052 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC323 isolate 683620
            SAMN38261939-rid24807223.denovo.012, whole genome shotgun sequence.
ACCESSION   DBEJAU010000012 DBEJAU010000000
VERSION     DBEJAU010000012.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261939
            Sequence Read Archive: SRR26833919
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 38052)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 38052)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576303.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576303.1
            Genome Coverage       :: 154x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/19/2025 01:05:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,121
            CDSs (total)                      :: 2,078
            Genes (coding)                    :: 1,943
            CDSs (with protein)               :: 1,943
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 36
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 72 of 135
            Pseudo Genes (incomplete)         :: 63 of 135
            Pseudo Genes (internal stop)      :: 51 of 135
            Pseudo Genes (multiple problems)  :: 46 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..38052
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261939-rid24807223.denovo.012"
                     /strain="GPSC323"
                     /isolate="683620"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            169..366
                     /locus_tag="ACL29Z_000703"
     CDS             169..366
                     /locus_tag="ACL29Z_000703"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001858369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0069046.1"
                     /translation="MIAEKVSKTLDKTFDKDVREIPTSQFYQKFVDEMGRTYSGNLIL
                     QELITVNGAYKATYIGELSSN"
     gene            497..1669
                     /locus_tag="ACL29Z_000704"
     CDS             497..1669
                     /locus_tag="ACL29Z_000704"
                     /EC_number="2.3.3.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004181031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004421 - hydroxymethylglutaryl-CoA
                     synthase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxymethylglutaryl-CoA synthase"
                     /protein_id="HGR0069047.1"
                     /translation="MTIGIDKIGFATSQYVLKLQDLAEARGIDPEKLSKGLLLKELSI
                     APLTEDIVTLAASASDSILTEQERQEVDMVIVATESGIDQSKAAAVFVHGLLGIQPFA
                     RSFEIKEACYGATAALHYAKLHVENSPESKVLVIASDIAKYGIETPGEPTQGAGSVAM
                     LITQNPRMMAFNNDNVAQTRDIMDFWRPNYSTTPYVNGVYSTQQYLDSLKTTWLEYQK
                     RYQLTLDDFAAVCFHLPYPKLALKGLKKIMDKSLPQEKKDLLQKHFDQSILYSQKVGN
                     IYTGSLFLGLLSLLENTDSLKAGDKIALYSYGSGAVAEFFSGELVEGYEAYLDKDRLN
                     KLNQRTALSVADYEKVFFEEVNLDETNSAQFAGYENQDFALVEILDHQRRYSKVEK"
     gene            1669..2943
                     /locus_tag="ACL29Z_000705"
     CDS             1669..2943
                     /locus_tag="ACL29Z_000705"
                     /EC_number="1.1.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000704367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004420 - hydroxymethylglutaryl-CoA
                     reductase (NADPH) activity [Evidence IEA];
                     GO_function: GO:0016616 - oxidoreductase activity, acting
                     on the CH-OH group of donors, NAD or NADP as acceptor
                     [Evidence IEA];
                     GO_process: GO:0015936 - coenzyme A metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxymethylglutaryl-CoA reductase,
                     degradative"
                     /protein_id="HGR0069048.1"
                     /translation="MKISWNGFSKKSYQERLELLKAQALLSPERQASLEKDEQMSVTV
                     ADQLSENVVGTFSLPYSLVPEVLVNGQEYTVPYVTEEPSVVAAASYASKIIKRAGGFT
                     AQVHQRQMIGQVALYQVANPKLAQEKIASKKAELLELANQAYPSIVKRGGGARDLHVE
                     QIKGEPDFLVVYIHVDTQEAMGANMLNTMLEALKPVLEELSQGQSLMGILSNYATDSL
                     VTASCRIAFRYLSRQKDQGREIAEKIALASQFAQADPYRAATHNKGIFNGIDAILIAT
                     GNDWRAIEAGAHAFASRDGRYQGLSCWTLDLEREELVGEMTLPMPVATKGGSIGLNPR
                     VALSHDLLGNPSARELAQIIVSIGLAQNFAALKALVSTGIQQGHMKLQAKSLALLAGA
                     SESEVAPLVERLISDKTFNLETAQRYLENLRS"
     gene            complement(2978..3942)
                     /locus_tag="ACL29Z_000706"
                     /pseudo
     CDS             complement(2978..3942)
                     /locus_tag="ACL29Z_000706"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002929307.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
     gene            complement(3923..5377)
                     /locus_tag="ACL29Z_000707"
     CDS             complement(3923..5377)
                     /locus_tag="ACL29Z_000707"
                     /EC_number="3.2.1.26"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000455313.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004564 - beta-fructofuranosidase activity
                     [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sucrose-6-phosphate hydrolase"
                     /protein_id="HGR0069049.1"
                     /translation="MEWTTERRYRLYQDWTQEEIQHIKENMAQSPWHTHYHVEPKTGL
                     LNDPNGFSYFDGKWILFYQNFPFGAAHGLKSWAQLESDDLVHFKETGIKVLPDTPLDS
                     HGAYSGSAMQFGDNLFLFYTGNVRDENWIRHPYQIGALMDKEGKITKIDKILIDQPAD
                     STDHFRDPQIFNFKGQYYAVVGGQDLEKKGFVRLYKAVNNDYTNWQAVGDLDFANDRT
                     AYMMECPNLVFVEEHPVLLYCPQGLDKKVLDYDNIFPNMYKIGASFDPKNAKMVDVSQ
                     LQNMDYGFEAYATQAFNAPDGRALAVSWLGLPDVSYPSDRFDHQGTFSLVKELTIKDD
                     KLYQYPVAAIKDLRASEEAFSNRSQTKNTYELELNLEANSQSEIVLLADKEGKGLSIN
                     FDLVNGQVTVDRSQAGEQYAQEFGTTRSCPIENQATTATIFIDNSVFEIFINKGEKVF
                     SGRVFPHADQNGILIKSGNPTGTYYELDYGRKTN"
     gene            5754..7637
                     /locus_tag="ACL29Z_000708"
     CDS             5754..7637
                     /locus_tag="ACL29Z_000708"
                     /EC_number="2.7.1.211"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864794.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sucrose-specific PTS transporter subunit IIBC"
                     /protein_id="HGR0069050.1"
                     /translation="MNNQEIAKKVIDALGGRENVNSVAHCATRLRVMVKDEEKINKEV
                     IENLEKVQGAFFNSGQYQIIFGTGTVNKMYDEVVVLGLPTSSKDDMKAEVAKQGNWFQ
                     RAIRTFGDVFVPIIPVIVATGLFMGVRGLFNALEMPLPGDFATYTQILTDTAFIILPG
                     LVVWSTFRVFGGNPAVGIVLGMMLVSGSLPNAWAVAQGGEVTAMNFFGFIPVVGLQGS
                     VLPAFIIGVVGAKFEKAVRKVVPDVIDLLVTPFVTLLVMSILGLFVIGPVFHVVENYI
                     LIATKAILSMPFGLGGFLIGGVHQLIVVSGVHHIFNLLEVQLLAADHANPFNAIITAA
                     MTAQGAATVAVGVKTKNPKLKTLAFPAALSAFLGITEPAIFGVNLRFRKPFFLSLIAG
                     AIGGGLASILGLAGTGNGITIIPGTMLYVGNGQLPQYLLMVAVSFALGFALTYMFGYE
                     DEVDATAAAKQAEVAEEKEEVAPAALQNETLVTPIVGDVVALADVNDPVFSSGAMGQG
                     IAVKPSQGVVYALADAEVSIAFPTGHAFGLKTRNGAEVLIHVGIDTVSMNGDGFEAKV
                     AQGNKVKAGDVLGTFDSNKIAAAGLDDTTMVIVTNTADYASVAPVATGSVSKGDAVIE
                     VKI"
     gene            7786..8673
                     /gene="scrK"
                     /locus_tag="ACL29Z_000709"
     CDS             7786..8673
                     /gene="scrK"
                     /locus_tag="ACL29Z_000709"
                     /EC_number="2.7.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000164317.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008865 - fructokinase activity [Evidence
                     IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="fructokinase ScrK"
                     /protein_id="HGR0069051.1"
                     /translation="MTKLYGSLEAGGTKFVCAVGDENFNVVEKTQFPTTTPIETIDKT
                     IEFFSKFDNLAGLAVGSFGPIDIDKNSKTYGFITTTPKPNWANVDLLGALRRALNVPM
                     YFTTDVNSSAYGEMVARNNAGGRIENLVYYTIGTGIGAGVIQRGEFIGGVGHPEMGHY
                     YVARHPMDIEKEFKGVCPFHKGCLEGYAAGPSLEARTGVRGENIELNNPVWDVQAYYI
                     AQAAVNATVTFRPDVIVFGGGVMAQQHMLDRVREKFTSLLNGYLPVPDVRDYIVTPAV
                     ARNGSATLGNFVLAKEVSK"
     gene            complement(8993..9610)
                     /locus_tag="ACL29Z_000710"
     CDS             complement(8993..9610)
                     /locus_tag="ACL29Z_000710"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000076166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TVP38/TMEM64 family protein"
                     /protein_id="HGR0069052.1"
                     /translation="MSQDKQMKAVSPLLQRVINISSIVGGVGSLIFCIWAYQAGILQS
                     KETLSAFIQQAGIWGPPLFIFLQILQTVVPIIPGALTSVAGVFIYGHIIGTIYNYIGI
                     VIGCAIIFYLVRLYGAAFVQSVVSKRTYDKYIGWLDKGNRFDRFFIFMMIWPISPADF
                     LCMLAALTKMSFKRYMTIIILTKPFTLVVYTYGLTYIIDFFWQML"
     gene            complement(10025..10213)
                     /locus_tag="ACL29Z_000711"
                     /pseudo
     CDS             complement(10025..10213)
                     /locus_tag="ACL29Z_000711"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_086558115.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
     gene            complement(10606..10797)
                     /locus_tag="ACL29Z_000712"
     CDS             complement(10606..10797)
                     /locus_tag="ACL29Z_000712"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0069053.1"
                     /translation="MTIKEQTRKLAVDCSKYSFEVADKTDEVSSKHCFEVVDRTDEVS
                     NYIYGKAKLTWFEEIFEEY"
     gene            10920..11813
                     /locus_tag="ACL29Z_000713"
     CDS             10920..11813
                     /locus_tag="ACL29Z_000713"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000895295.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGR0069054.1"
                     /translation="MLEVRSLEKSFGSKQVLFGIDFQARPGRILGLVGKNGAGKTTIF
                     HSILKFLEYQGEIGLDGQDIRQETYARIGYLPEERSLMPKLTVLEQVRYLATLKGMDA
                     KEVKEKLPQWMKRLEVKGKLTDKIKSLSKGNQQKIQLIITLIHEPDLIILDEPFSGLD
                     PVNTELLKQVIFQEKERGATIIFSDHVMTNVEELCDDILMIRDGRVVLHGPIQDVRNQ
                     YGKTRLFVSSERSKEELENLPHVKQVSLTKQGSWKLILEDESAGRELFPILTQGQYIA
                     TFDQQAPTIDEIFKLESGVEV"
     gene            11810..13009
                     /locus_tag="ACL29Z_000714"
     CDS             11810..13009
                     /locus_tag="ACL29Z_000714"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001245382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HGR0069055.1"
                     /translation="MRNMWVVIKETYLRHVKSWSFFFMVISPFLFLGISVGIGHIQGS
                     SMAKNNKVAVVTTVPSVAEGLKNVNGVNFDYKDEASAKEAIKEEKLKGYLTIDQEDSV
                     LKAVYHGETSLENGIKFEVTGTLNELQNQLNRSTASLSQEQEKRLAQTIQFTEKIDEA
                     KENKKFIQTIAAGALGFFLYMILITYAGVTAQEVASEKGTKIMEVVFSSIRASHYFYA
                     RMMALFLVILTHIGIYVVGGLAAVLLFKDLPFLAQSGILVHLGDAISLNTLLFILISL
                     FMYVVLAAFLGSMASRPEDSGKALSPLMILIMGGFFGVTALGAAGDNLLLKIGSYIPF
                     ISTFFMPFRTINGYAGGAEAWISLAITVIFAVVATGFIGRMYASLVLQTDDLGIWKTF
                     KRALSYK"
     gene            complement(13362..14129)
                     /locus_tag="ACL29Z_000715"
     CDS             complement(13362..14129)
                     /locus_tag="ACL29Z_000715"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000498762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0069056.1"
                     /translation="MFWNLVHYEFKNVNKWYLALYAAVLVLSALIGIQTQGFKNLPYQ
                     ESQATMLLFLATVFGGLMLTLAISTIFLIIKRFKGSVYDRQGYLTLTLPVSEHHIITA
                     KLIGAFIWSLISTAVLALSAVIILALTAPEWIPLSYVITFVETHLPQIFLTGISFLLN
                     TISGILCIYLAISIGQLFNEYRTALAVAAYIGIQIVIGFIELFFNLSSNFYVNSLVGL
                     NDHFYMGAGIAIVKELIFIAIFYLGTYYILRNKVNLL"
     gene            complement(14146..14841)
                     /locus_tag="ACL29Z_000716"
     CDS             complement(14146..14841)
                     /locus_tag="ACL29Z_000716"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004256110.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGR0069057.1"
                     /translation="MSLLAFENVSKSYGATPALENVSLDIPAGKIVGLLGPNGSGKTT
                     LIKLINGLLQPDQGRVLINDMDPSPATKAVVAYLPDTTYLNEQMKVKEALTYFKTFYK
                     DFNLERAHHLLADLGIDENSRLKKLSKGNKEKVQLILVMSRDARLYVLDEPIGGVDPA
                     ARAYILNTIINNYSPTSTVLISTHLISDIEPILDEIVFLKDGKVVRQGNVDDIRYESG
                     ESIDQLFRQEFKA"
     gene            complement(14846..15211)
                     /locus_tag="ACL29Z_000717"
     CDS             complement(14846..15211)
                     /locus_tag="ACL29Z_000717"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004256112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HGR0069058.1"
                     /translation="MSWTFDNKKPIYLQIMEKIKLQIVSHTLEPNQQLPTVRELASEA
                     GVNPNTIQRALSDLEREGFVYSKRTTGRFVTKDKELIAQSRKQLSEEELEHFVSSMTH
                     FGYEKEELPGVVSDYIKGV"
     gene            15351..15824
                     /gene="nrdR"
                     /locus_tag="ACL29Z_000718"
     CDS             15351..15824
                     /gene="nrdR"
                     /locus_tag="ACL29Z_000718"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001203675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_function: GO:0140110 - transcription regulator activity
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator NrdR"
                     /protein_id="HGR0069059.1"
                     /translation="MRCPKCGATKSSVIDSRQAEEGNTIRRRRECDECQHRFTTYERV
                     EERTLVVVKKDGTREQFSRDKIFNGIIRSAQKRPVSSDEINMVVNRIEQKLRGRNENE
                     IQSEDIGSLVMEELAELDEITYVRFASVYRSFKDVSELESLLQQITQSSKKKKER"
     gene            15825..16994
                     /locus_tag="ACL29Z_000719"
     CDS             15825..16994
                     /locus_tag="ACL29Z_000719"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000802368.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DnaD domain protein"
                     /protein_id="HGR0069060.1"
                     /translation="MKPIDRFSYLKNNRVSQDTSSLVQCYLPIIGQEALSLYLYTISF
                     WDNGRKEYLFSSILNHLNFGMDRLIKSLKILSAFNLLTLYQKGDVYQLALHAPLSSQD
                     FLGHPVYRRLLEKKIGDVAVEDLKVESADGEEIPVSLNQVFPELAELGSQEDLGLKKK
                     VANDFDLEHFRQLMARDGLRFADEQSDVLNLFAIAEEKKWTWFETYQLAKSTAVSQVI
                     STKRMREKIAQKPVSSDFSLKEATIIKEAKSKTALQFLAEIKQTRKGTITQTERELLQ
                     QMAGLGLLDEVINIILLLTFNKVDSANINEKYAMKVANDYAYQKIHSAEEAVLRIRDR
                     GQKAKTQKQNQTAPEKTNVPKWSNPEYKNETSEETRLELERKKQELLARLEKGGD"
     gene            16995..17891
                     /gene="dnaI"
                     /locus_tag="ACL29Z_000720"
     CDS             16995..17891
                     /gene="dnaI"
                     /locus_tag="ACL29Z_000720"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398880.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="primosomal protein DnaI"
                     /protein_id="HGR0069061.1"
                     /translation="MESVGDVLKRQPSRFYYQDLVQKIMKDPDVAAFIQQESLTPKEL
                     NRSISKFNQYITERDKFLRGDTDYIAKGYKPILVKNHGYADVSYEETPELIAAEKEAA
                     IKNRLKLINLPASLKKASLAQVDLDDLGRLPVFEKLLAFVEQYPAIRKGLYLYGDFGV
                     GKSFMVAALAHDLSEKRGVSSTLLHYPSFVIDVKNAISDGNVKTLVDEIKLSEVLILD
                     DIGAEQSTVWVRDEILQVILQYRMQENLPTFFTSNFNFEDLEKHFAKVKHGNDETWEA
                     RRVMERIRYLAEETRLEGVNRR"
     gene            17888..18601
                     /locus_tag="ACL29Z_000721"
     CDS             17888..18601
                     /locus_tag="ACL29Z_000721"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000140867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADPH-dependent oxidoreductase"
                     /protein_id="HGR0069062.1"
                     /translation="MTETIKLMKAHTSVRRFKEQEIPQVDLNEILTAAQMASSWKNFQ
                     SYSVIVVRSQEKKDALYELVPQEAIRQSAVFLLFVGDLNRAEKGARLHTDTFQPQGVE
                     GLLISSVDAALAGQNALLAAESLGYGGVIIGLVRYKSEEVAELFNLPDYTYSVFGMAL
                     GVPNQHHDMKPRLPLENVVFEEEYQEQSTEAIQAYDRVQADYAGARATTSWSQRLAEQ
                     FGQAEPSSTRKNLEQKKLL"
     gene            18615..19925
                     /gene="der"
                     /locus_tag="ACL29Z_000722"
     CDS             18615..19925
                     /gene="der"
                     /locus_tag="ACL29Z_000722"
                     /EC_number="3.6.5.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018377046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_function: GO:0043022 - ribosome binding [Evidence IEA];
                     GO_process: GO:0042254 - ribosome biogenesis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase Der"
                     /protein_id="HGR0069063.1"
                     /translation="MALPTIAIVGRPNVGKSTLFNRIAGERISIVEDVEGVTRDRIYA
                     TGEWLNRSFSMIDTGGIDDVDAPFMEQIKHQAEIAMEEADVIVFVVSGKEGITDADEY
                     VARKLYKTHKPVILAVNKVDNPEMRNDIYDFYALGLGEPLPISSVHGIGTGDVLDAIV
                     ENLPNEYEEENPDVIKFSLIGRPNVGKSSLINAILGEDRVIASPVAGTTRDAIDTHFT
                     DTDGQEFTMIDTAGMRKSGKVYENTEKYSVMRAMRAIDRSDVVLMVINAEEGIREYDK
                     RIAGFAHEAGKGMIIVVNKWDTLEKDNHTMKNWEEDIREQFQYLPYAPIIFVSALTKQ
                     RLHKLPEMIKQISESQNTRIPSAVLNDVIMDAIAINPTPTDKGKRLKIFYATQVATKP
                     PTFVIFVNEEELMHFSYLRFLENQIRKAFVFEGTPIHLIARKRK"
     gene            20014..20349
                     /locus_tag="ACL29Z_000723"
     CDS             20014..20349
                     /locus_tag="ACL29Z_000723"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000400494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0069064.1"
                     /translation="MEHLFKFLLLAPYFYFDNWIEKANRNSKFFPIFYYFYWFYIPFY
                     SLFSLAWTVVSVLFFNTVLRNVTDIKLWGIWFLFILLAIGMNWLTYSCFKEMFRLRQE
                     LGKSKGGRH"
     gene            20489..20824
                     /locus_tag="ACL29Z_000724"
     CDS             20489..20824
                     /locus_tag="ACL29Z_000724"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000400498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0069065.1"
                     /translation="MEHLFKMIILLPCFYFFSWIDKDNRESKFFPIFYYFYWIYITLY
                     ALFSLAWTVFSVLFFNIVLRNLTDIKLWGIWLLLLLIAFASDWLAYVFFKKMLDLRRE
                     LGKSKGGRH"
     gene            21009..21800
                     /locus_tag="ACL29Z_000725"
     CDS             21009..21800
                     /locus_tag="ACL29Z_000725"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398883.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0069066.1"
                     /translation="MKIPLLTFARHKFVYVLLTLLFLALVYRDVLMTYFFFDIHAPDL
                     AKFDGQAIKNDLLKSALDFRILQFNLGFYQSFIIPIIIVLLGFQYIELKNKVLRLSIG
                     REVSYQGLKRKLTLQVASIPCLIYLVTVLIIAIITYFFGTFSPLGWNSLFSDGSGLQR
                     LLDGEIKSYLFFTCVLLIGIFINAIYFLQIVDYVGNVTRSAITYLMFLWLGSMLLYSA
                     LPYYMVPMTSLMQASYGDVSLMKLFTPYILYIVPYMVLEKYEDNV"
     gene            21793..22434
                     /locus_tag="ACL29Z_000726"
     CDS             21793..22434
                     /locus_tag="ACL29Z_000726"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000475766.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0069067.1"
                     /translation="MFKNFNNILLNRKIVLLLRIVLMMILINHLLSTAVQKQDAVIFF
                     KRELISIFSYNDYSEANLEIPKLLLNLSLFMVGWLSVILLESDLADHYHHLIRYQSSS
                     FFDYTRKRLVVISKFFTQDLFVWFLGLLPLGIHFKTVALFFLLAQLMMLYLLLSYLIA
                     LISAGAGFSFFLYFLAFVGQEWMMDHIVTVYLVLLSLLVMLIVSRLEEKFKKG"
     gene            22438..23070
                     /locus_tag="ACL29Z_000727"
     CDS             22438..23070
                     /locus_tag="ACL29Z_000727"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001235275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HGR0069068.1"
                     /translation="MRLEIINGQKIYGKRPILNQLNLVFQSGKIYGLKGDNGSGKTVL
                     LKILAGYIKLDKGKVLQDGKVYGVKNHYIQDAGILIEKVEFLSHLSLRENLELLRYFS
                     SKVTEKRIAYWIQYYDLQEFEDIEYRHLSLGTKQKMALIQAFISSPSILFLDEPMNAL
                     DEKSVRLTKQVILSYLKKENGLVILTSHISEDISDLCTDVLVVENGHIQM"
     gene            23098..23385
                     /locus_tag="ACL29Z_000728"
     CDS             23098..23385
                     /locus_tag="ACL29Z_000728"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000940707.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0069069.1"
                     /translation="MAHLKSFITRYSKVYIGLVLLIWLSFFFIPWDKPLLGIRIDIFI
                     IQKILLAFGILSILMALLSKKVSLFVFGLICCLSLWINLFITFAILPIFGN"
     gene            23531..26044
                     /gene="secA"
                     /locus_tag="ACL29Z_000729"
     CDS             23531..26044
                     /gene="secA"
                     /locus_tag="ACL29Z_000729"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398886.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009898 - cytoplasmic side of plasma
                     membrane [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0015450 - protein-transporting ATPase
                     activity [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_process: GO:0043952 - protein transport by the Sec
                     complex [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecA"
                     /protein_id="HGR0069070.1"
                     /translation="MANILKTIIENDKGEIRRLEKMADKVFKYEDQMAALTDDQLKAK
                     TVEFKERYQNGESLDSLLYEAFAVVREGAKRVLGLFPYKVQVMGGIVLHHGDVPEMRT
                     GEGKTLTATMPVYLNALSGKGVHVVTVNEYLSERDATEMGELYSWLGLSVGINLATKS
                     PMEKKEAYECDITYSTNSEIGFDYLRDNMVVRAENMVQRPLNYALVDEVDSILIDEAR
                     TPLIVSGANAVETSQLYHMADHYVKSLNKDDYIIDVQSKTIGLSDSGIDRAESYFKLE
                     NLYDIENVALTHFIDNALRANYIMLLDIDYVVSEEQEILIVDQFTGRTMEGRRYSDGL
                     HQAIEAKEGVPIQDETKTSASITYQNLFRMYKKLSGMTGTGKTEEEEFREIYNIRVIP
                     IPTNRPVQRIDHSDLLYASIESKFKAVVEDVKARYQKGQPVLVGTVAVETSDYISKKL
                     VAAGVPHEVLNAKNHYREAQIIMNAGQRGAVTIATNMAGRGTDIKLGEGVRELGGLCV
                     IGTERHESRRIDNQLRGRSGRQGDPGESQFYLSLEDDLMKRFGSERLKGIFERLNMSE
                     EAIESRMLTRQVEAAQKRVEGNNYDTRKQVLQYDDVMREQREIIYAQRYDVITADRDL
                     APEIQSMIKRTIERVVDGHARAKQDEKLEAILNFAKYNLLPEDSITMEDLSGLSDKAI
                     KEELFQRSLKVYDSQVSKLRDEEAVKEFQKVLILRVVDNKWTDHIDALDQLRNAVGLR
                     GYAQNNPVVEYQAEGFRMFNDMIGSIEFDVTRLMMKAQIHEQERPQAERHISTTATRN
                     IAAHQASMPEDLDLSQIGRNELCPCGSGKKFKNCHGKRQ"
     gene            26125..27156
                     /locus_tag="ACL29Z_000730"
     CDS             26125..27156
                     /locus_tag="ACL29Z_000730"
                     /EC_number="2.5.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000232189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016832 - aldehyde-lyase activity
                     [Evidence IEA];
                     GO_process: GO:0009073 - aromatic amino acid family
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="3-deoxy-7-phosphoheptulonate synthase"
                     /protein_id="HGR0069071.1"
                     /translation="MVFTAKSSKINIEEVRALSKLEGQALERKSQRDQELEAIIRGED
                     QRILLVIGPCSSDNEEAVLEYAKRLAVLQEEVADRIFMVMRVYTAKPRTNGDGYKGLI
                     HQPNATEAPSLINGIKAVRHLHYRVITETGMTTADEMLYPENLPLVDDLISYMAVGAR
                     SVEDQQHRFVASGAGFSTGFKNPTSGNLNVMFNGIYAAQNKQSFLFLGKEVETTGNPL
                     SHAILRGALNEYGKNIPNYYYDNLIDTIAQYEKMGLENPFIIIDTNHDNSGKQYIEQI
                     RIVRQTLINRAWNEKIKQFVRGFMIESYLEDGRQNEPEVFGKSITDPCLGWDNTEALV
                     REIYKTLGE"
     gene            27158..28189
                     /locus_tag="ACL29Z_000731"
     CDS             27158..28189
                     /locus_tag="ACL29Z_000731"
                     /EC_number="2.5.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016832 - aldehyde-lyase activity
                     [Evidence IEA];
                     GO_process: GO:0009073 - aromatic amino acid family
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="3-deoxy-7-phosphoheptulonate synthase"
                     /protein_id="HGR0069072.1"
                     /translation="MAFIEKGQEIDMEVIKAETQLSAEALRLKESRDRELADIISGED
                     DRILLVIGPCSSDNEEAVLEYARRLSALQKKVADKIFMVMRVYTAKPRTNGDGYKGLV
                     HQPDTSKAPSLINGLQAVRQLHYRVITETGLTTADEMLYPSNLILVDDLVSYHAVGAR
                     SVEDQEHRFVASGIDAPVGMKNPTSGNLGVMFNAIYAAQNKQTFLYHGQEVETSGNPL
                     AHVILRGAVNEYGNYMPNYYYENLLQAIERYETMGLENPFILIDTNHDNSGKQYMEQI
                     RIVRQTLQNRDWNEKIKKTVRGFMIESYLADGRQNQPEIFGCSITDPCLGWENTEALV
                     EEIYVTLTK"
     gene            28234..28596
                     /gene="acpS"
                     /locus_tag="ACL29Z_000732"
     CDS             28234..28596
                     /gene="acpS"
                     /locus_tag="ACL29Z_000732"
                     /EC_number="2.7.8.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007521175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008897 - holo-[acyl-carrier-protein]
                     synthase activity [Evidence IEA];
                     GO_process: GO:0008610 - lipid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="holo-ACP synthase"
                     /protein_id="HGR0069073.1"
                     /translation="MIVGHGIDIEELASIESAVTRHEGFAKRVLTAQEMERFTSLKGR
                     RQIEYLAGRWSAKEAFSKAMGTGISKLGFQDLEVLNNERGAPYFSQAPFSGKIWLSIS
                     HTDQFVTASVILEENHES"
     gene            28586..29689
                     /gene="alr"
                     /locus_tag="ACL29Z_000733"
     CDS             28586..29689
                     /gene="alr"
                     /locus_tag="ACL29Z_000733"
                     /EC_number="5.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000648075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008784 - alanine racemase activity
                     [Evidence IEA];
                     GO_process: GO:0006522 - alanine metabolic process
                     [Evidence IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alanine racemase"
                     /protein_id="HGR0069074.1"
                     /translation="MKASPHRPTKALIHLGAIRQNIQQMGAHIPQGTLKLAVVKANAY
                     GHGAVAVAKAIQDDVDGFCVSNIDEAIELRQAGLSKPILILGVSEIEAVALAKEYDFT
                     LTVAGLEWIQALLDKEVDLTGLTVHLKIDSGMGRIGFREASEVEQAQDLLQQHGVCVE
                     GIFTHFATADEESDDYFNAQLERFKTILASMKEVPELVHASNSATTLWHVETIFNAVR
                     MGDAMYGLNPSGAVLDLPYDLIPALTLESALVHVKTVPAGACMGYGATYQADSEQVIA
                     TVPIGYADGWTRDMQNFSVLVDGQACPIVGRVSMDQITIRLPKLYPLGTKVTLIGSNG
                     DKEITATQVATYRVTINYEVVCLLSDRIPREYY"
     gene            29708..31723
                     /gene="recG"
                     /locus_tag="ACL29Z_000734"
     CDS             29708..31723
                     /gene="recG"
                     /locus_tag="ACL29Z_000734"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001048793.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0003678 - DNA helicase activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent DNA helicase RecG"
                     /protein_id="HGR0069075.1"
                     /translation="MNLHQPLHVLPGVGPKSAEKYAKLGIENLQDLLLYFPFRYEDFK
                     TKQVLELEDGEKAVLSGQVVTPASVQYYGFKRNRLRFSLKQGEVVFAVNFFNQPYLAD
                     KIELGATLAVFGKWDCAKASLTGMKVLAQVEDDLQPVYRLAQGISQASLVKVIKTAFD
                     QGLDLLIEENLPQSLLDKYKLMSRCQAVRAMHFPKYLAEYKQALRRIKFEELFYFQMQ
                     LQMLKSENRVQGSGLVLNWSQEKVTAVKVSLPFALTQAQEKSLQEILTDMKSDHHMNR
                     LLQGDVGSGKTVVAGLAMFAAVTAGYQAALMVPTEILAEQHFESLQNLFPNLKLALLT
                     GSLKAAEKREVLETIAKGEADLIIGTHALIQDGVEYARLGLIIIDEQHRFGVGQRRIL
                     REKGDNPDVLMMTATPIPRTLAITAFGDMDVSIIDQMPAGRKPIVTRWIKHEQLPQVL
                     TWLEGEIQKGSQVYVISPLIEESEALDLKNAIALSEELTTHFAGKAEVALLHGRMKSD
                     EKDQIMQDFKERKTDILVSTTVIEVGVNVPNATVMIIMDADRFGLSQLHQLRGRVGRG
                     DKQSYAVLVANPKTDSGKDRMRIMTETTNGFVLAEEDLKMRGSGEIFGTRQSGLPEFQ
                     VADIIEDFPILEEARKVASYISSIEAWQEDPEWRMIALHLEKKEHLD"
     gene            31751..31900
                     /locus_tag="ACL29Z_000735"
     CDS             31751..31900
                     /locus_tag="ACL29Z_000735"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0069076.1"
                     /translation="MKIKEQTRKLTAGCSKHCFEVVDETDEVSSKHRFEVADRTDEVS
                     NIYIR"
     gene            32238..33218
                     /locus_tag="ACL29Z_000736"
     CDS             32238..33218
                     /locus_tag="ACL29Z_000736"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetylxylan esterase"
                     /protein_id="HGR0069077.1"
                     /translation="MKNPALLEEIKTYRGRDEVPEDFDDFWDGEVKNVSTLPSYHLEE
                     RDFHIPQVKCYELTFEGSKEGKVYARIVLPKSEEKVPLIFHFHGYMGRGWDWADMLGF
                     TVAGYGVVSMDVRGQSGYSQDGLRSPLGNTVKGHIIRGAVEGRDHLFYKDVYLDIYQL
                     VEIVASLSQVDEKRLSSYGASQGGALALVAAALNPRIQKTVAIYPFLSDFRRVIEIGN
                     TSEAYDELFRYFKFHDPFHETEEEIMATLAYIDVKNLAHRIQGEVKMITGLDDDVCYP
                     ITQFAIYNRLTCDKTYRIMPEYAHEAMNVFVNDQVYNWLCGSEIPFKYLK"
     gene            33978..34205
                     /locus_tag="ACL29Z_000737"
     CDS             33978..34205
                     /locus_tag="ACL29Z_000737"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000576349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0069078.1"
                     /translation="MIFKAFKTKKQRKRQVELLLTVFFDSFLIDLFLHLFGIVPFKLD
                     KILIVSLIIFPIISTSIYAYEKLFEKVFDKD"
     gene            34493..37390
                     /gene="nanA"
                     /locus_tag="ACL29Z_000738"
     CDS             34493..37390
                     /gene="nanA"
                     /locus_tag="ACL29Z_000738"
                     /EC_number="3.2.1.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014632427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG-anchored neuraminidase NanA"
                     /protein_id="HGR0069079.1"
                     /translation="MNRSVQERKCRYSIRKLSVGAVSMIVGAVVFGTSPVLAQEGASE
                     QPLANETQLSGESSTLTDTEKSQPSSETELSGNKQEQERKDKQEEKIPRDYYARDLEN
                     VETVIEKEDVETNASNGQRVDLSSELDKLKKLENATVHMEFKPDAKAPAFYNLFSVSS
                     ATKKDEYFTMAVYNNTATLEGRGSDGKQFYNNYNDAPLKVKPGQWNSVTFTVEKPTAE
                     LPKGRVRLYVNGVLSRTSLRSGNFIKDMPDVTHVQIGATKRANNTVWGSNLQIRNLTV
                     YNRALTPEEVQKRSQLFKRSDLEKKLPEGAALTEKTDIFESGRNGNPNKDGIKSYRIP
                     ALLKTDKGTLIAGADERRLHSSDWGDIGMVIRRSEDNGKTWGDRVTITNLRDNPKASD
                     PSIGSPVNIDMVLVQDPETKRIFSIYDMFPEGKGIFGMSSQKEEAYKKIDGKTYQILY
                     REGEKGAYTIRENGTVYTPDGKATDYRVVVDPVKPAYSDKGDLYKGDQLLGNIYFTTN
                     KTSPFRIAKDSYLWMSYSDDDGKTWSAPQDITPMVKADWMKFLGVGPGTGIVLRNGPH
                     KGRILIPVYTTNNVSHLDGSQSSRVIYSDDHGKTWHAGEAVNDNRQVDGQKIHSSTMN
                     NRRAQNTESTVVQLNNGDVKLFMRGLTGDLQVATSKDGGVTWEKDIKRYPQVKDVYVQ
                     MSAIHTMHEGKEYIILSNAGGPKRENGMVHLARVEENGELTWLKHNPIQKGEFAYNSL
                     QELGNGEYGILYEHTEKGQNAYTLSFRKFNWEFLSKNLISPTEAKVKRTREMGKGEMG
                     KGVIGLEFDSEVLVNKAPTLQLANGKTATFLTQYDSKTLLFAVDKEDIGQEIIGIAKG
                     SIESMHNLPVNLAGARVPGGVNGSKAAVHEVPEFTGGVNGTEPAVHEIAEYKGSDSLV
                     TLTTKKDYTYKAPLAQQALPETGNKESDLLASLGLTAFFLGLFTLGKKREQ"
     gene            complement(37458..>38052)
                     /locus_tag="ACL29Z_000739"
     CDS             complement(37458..>38052)
                     /locus_tag="ACL29Z_000739"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_086558202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /codon_start=2
                     /transl_table=11
                     /product="ISL3-like element IS1167 family transposase"
                     /protein_id="HGR0069080.1"
                     /translation="QLFPCAKIVLDRFHIVQHLSRAMSRVRVQIMNQLDRKSHEYKAI
                     KRYWKLIQQDSRKLSDKHFYRPTFRMHLTNKEILNKLLSYSQDLKHHYQLYQLLLFHF
                     QNKEPEKFFGLIEDNLKQVHPLFQTVFKTFLKDKEKIVNALQLHYSNAKLEATNNLIK
                     LIKRNAFGFRNFENFKKRIFIALNIKKERTKFVLSRA"
BASE COUNT        11372 a         7090 c         8507 g        11083 t
ORIGIN      
        1 tacgaatgaa tttgagtgct ggtattatca atcatgaact aggattctag ttttgcagga
       61 agtctactac tttccttatt gtctgtaaat ctactgacct tgttgtttat cccagtcatg
      121 gtttctagtt cgggctcaga gtttcaaagt ggatggtaag agcatcaatt gattgctgag
      181 aaggttagta aaacacttga caagacattt gataaggatg tcagagaaat tccgaccagt
      241 cagttttatc aaaaatttgt agatgagatg ggaaggactt actcaggaaa tttgatcctc
      301 caggagctga taactgtgaa tggagcttat aaagctactt atatcggtga actctctagc
      361 aactaatcat tctttaaaat gatgaccaat aagaggcttg atttggtgaa tcaagtcttt
      421 tttctctctt ttactgccat ttgtgataaa atagtataga acgatttttt acatgaatga
      481 taaaacagag gtaaatatga caatcggtat tgataagatt ggttttgcga ccagtcaata
      541 tgtcttgaaa ttacaagact tagcagaagc gaggggaatt gaccctgaaa aattaagtaa
      601 aggactctta ctcaaggaat tgagtattgc gcccctaact gaggatatcg tgaccttggc
      661 ggccagtgct agtgactcta ttttaactga gcaagaaaga caagaagttg acatggtcat
      721 tgtggcgacc gagtcaggaa ttgaccagag taaggctgcg gccgtctttg tgcatggctt
      781 gctgggcatc cagccctttg ctcgtagttt cgagattaaa gaagcctgct atggggcgac
      841 agctgccctc cattatgcca aattgcatgt ggaaaattct ccggagtcca aggtcttggt
      901 cattgccagt gatattgcca aatatggtat tgaaactccg ggagaaccca ctcagggtgc
      961 cggaagtgtg gctatgttga ttacacaaaa tccacgcatg atggccttta ataatgacaa
     1021 tgtagctcag acccgtgaca tcatggattt ctggcgacca aattactcga caactcctta
     1081 tgtaaatggt gtctattcta cccaacaata cttggatagt ttgaaaacga cttggcttga
     1141 atatcaaaaa cgctaccagc ttactctgga tgattttgcg gctgtttgtt tccacttgcc
     1201 ttatcctaaa ttagcgctaa aaggcttgaa aaaaatcatg gataagagcc tgcctcaaga
     1261 gaaaaaagac ctcttacaaa agcattttga ccagtctatt ctctacagtc aaaaggtggg
     1321 gaatatctac acaggttcac ttttccttgg acttttgtct ctcttggaaa atacagatag
     1381 cttgaaagct ggggataaaa tcgcccttta tagttacgga agtggagctg tggctgagtt
     1441 cttcagtggt gaattggttg aaggatatga agcttatttg gataaagacc gcttgaacaa
     1501 gctcaaccaa cgaactgccc tatccgttgc agactatgaa aaggtctttt ttgaggaagt
     1561 aaacttggat gaaacaaact ctgcccagtt tgctggctat gaaaatcaag attttgcctt
     1621 ggttgaaatt cttgaccacc aacgccgtta tagcaaggtt gaaaaataat gaagataagt
     1681 tggaatggat tttctaaaaa atcataccaa gagcgcctcg agctgctaaa agctcaggcg
     1741 ctccttagtc ctgagagaca agctagtctg gagaaggatg aacagatgag tgtgactgtg
     1801 gcagaccagc tgagtgagaa tgtggtggga actttttctc tgccttattc gctggttccg
     1861 gaggtacttg tcaacggtca ggaatacacc gttccctatg tgacagaaga accctctgtg
     1921 gttgcggcgg ccagctatgc cagcaaaatc atcaagcgtg caggtggttt tactgcacaa
     1981 gtccatcagc gccagatgat tgggcaggta gccctttatc aagttgctaa tcctaaacta
     2041 gcgcaagaga agattgccag caagaaagcg gagctcttgg agcttgccaa tcaagcctat
     2101 ccttctatcg ttaaacgtgg gggtggggcg cgtgatctgc atgtcgagca gataaaaggc
     2161 gaaccagact ttctcgttgt ttatattcat gtcgataccc aggaagccat gggtgccaat
     2221 atgctcaaca ccatgctgga agccttgaaa ccagtcttag aagaactcag tcagggacag
     2281 agtctcatgg gaatcctgtc caactacgcg actgattctc tggtgactgc aagctgtcgc
     2341 atcgcctttc gctacttgag ccgccaaaag gatcaaggac gagagattgc ggagaaaatt
     2401 gcgttggcta gtcagtttgc gcaggctgat ccttaccgag ctgctactca taataaagga
     2461 atttttaatg gtattgatgc gattttgatt gccactggta atgactggcg tgccatcgaa
     2521 gctggggccc atgcctttgc cagtcgagat ggacgctatc aaggtcttag ctgctggacg
     2581 ctggaccttg aaagagaaga attggtcggt gagatgaccc tgcccatgcc tgtagcgact
     2641 aagggtggct ctatcggcct caacccacgt gtagctctca gtcatgatct actaggaaat
     2701 ccttctgcca gagaattagc ccagattatc gtgtccatcg gtcttgctca aaattttgca
     2761 gccctcaaag ccttggtaag tacgggcatc cagcaaggcc acatgaaact acaggccaaa
     2821 tccctagctc tcctagctgg ggctagtgaa tctgaagttg ctcccctagt agagcgcctc
     2881 atctcagata aaacctttaa cctagagaca gcccagcgct atctcgaaaa tttaagatca
     2941 taaaaactca gacgaatcgg tctgagtttt cttgtgttta aatacttttt cctggtaata
     3001 gtgtaactgg taagaagtaa ccagttgtgg cgacttcctt gccttcaatc ttttgcaaga
     3061 gaagatcaat agtgagacaa gcaatctctt ccaaaggttg cttgatagta gccaattgag
     3121 ggtagtaatt ttcgataaag taggtcccat catagccgat gaccttgagc tcttttggga
     3181 cagaaatgcc caattcttga gcgattttaa tgaccagaat agctgtcaaa tcatccgaag
     3241 caaaaatggc atctggtttt tcccgggtca agatattctt gatttccatt tcttttctga
     3301 cgggagaaaa gaaatggaaa cattgataat aggagctttt gggagtacgg atgcaaaacc
     3361 agcgtggcgc agtccggttg gcgaattgga attgtcattc cctgtaatca tgatgataga
     3421 ctgggcacct gtcttgacca aggtttgggc agcaagaacc ccaccagcat agttgtcaga
     3481 ggagacaaca gggatgtctg gcgataggtt tcggtcaaag gaaataatcg gcgctgtcac
     3541 acgattgtag tcttcgattc ctaggttgtg actaccagaa atgatgccgt ctacctgatt
     3601 ggcttccaac atttcgatgt attcgcgttc cttctcagaa tcatgttcac tgttgcagat
     3661 gatggtcttg taaccatttt tgaagagttg gtgttccaat ttatcaatca attctgcata
     3721 gaaaacattg gaaatattgg ggaaaatcaa gccgattaac ttagctgatt ttccttgcag
     3781 actacgagcc aggttgttgg gtttatagcc taattctctc atggcttcat tgactttttg
     3841 gatggttttc tcagatagat atcctttttt attgataacc cgagaaacgg tagtaggact
     3901 gacgcctgca agtttggcga catcagttag ttttgcgacc ataatctaat tcatagtaag
     3961 ttccagttgg gtttccagat ttgatcagga taccattttg gtccgcatgt gggaagacac
     4021 gaccagaaaa tactttttct cctttattga tgaaaatttc aaagacagag ttatcgatga
     4081 agattgtagc agtagtagcc tgattctcga tagggcaaga acgagttgtc ccaaattctt
     4141 gggcatactg ttctccagcc tggctacgat ccactgtcac ttgaccgttt acaaggtcaa
     4201 agttgattga aagtccctta ccttctttat cagcaagtaa gacaatctcg ctctggctat
     4261 tagcttccaa gttgagttca agttcgtaag tgttcttggt ttgggaacgg tttgagaagg
     4321 cttcttcaga agcacgaagg tccttaatag cagcgactgg atactggtag agcttgtcgt
     4381 ctttgatagt gagttccttg accaaagaga aggttccttg gtggtcaaaa cggtcagatg
     4441 ggtaagaaac atctggcaaa ccaagccagc taactgctag agcacgccca tcaggagcgt
     4501 tgaaggcttg agttgcatag gcttcgaaac cgtaatccat gttttgaagt tgagacacat
     4561 ctaccatttt ggcattttta gggtcaaagg aagccccaat cttatacata tttggaaaga
     4621 tattatcgta gtctagaact ttcttatcca atccttgtgg acagtagaga aggacaggat
     4681 gttcctctac aaagaccaga ttaggacatt ccatcatgta ggcagtacgg tcgttagcaa
     4741 agtcaaggtc gccaactgct tgccagtttg tgtagtcgtt attgacagcc ttgtagagac
     4801 ggacgaagcc ttttttctcc aagtcctgtc caccgacgac agcatagtat tgacctttaa
     4861 agttaaaaat ttgtggatcg cggaagtggt cagtagagtc tgctggctgg tcaatcaaga
     4921 tcttgtcaat ctttgtaatc ttaccctcct tgtccatcaa agcaccgatc tggtatgggt
     4981 gacggatcca gttttcatcg cgaacatttc ctgtataaaa taggaataag ttatcgccaa
     5041 attgcatggc agaaccagag taggcaccgt ggctatctaa tggagtatct ggtaaaactt
     5101 tgattccagt ttctttaaag tgaaccaaat catcactttc tagctgtgcc caagatttca
     5161 aaccgtgggc tgcaccaaaa ggaaaattct ggtaaaagag gatccacttg ccatcaaagt
     5221 aagaaaagcc atttgggtcg ttgagaagtc ctgtttttgg ctcaacatgg taatgagtat
     5281 gccatggaga ttgtgccata ttttccttta tatgttgaat ttcttcttgc gtccaatctt
     5341 gataaagtct gtaacgacgc tcagttgtcc attccattca ttcctccaaa aatcttatca
     5401 cttttaatag taactgtttt cgataaaaaa tgcaagcctt ttatgttaaa aaagaggaaa
     5461 aactatcaaa cgattatcat aaaataaata caggaaatca atcaaatttt tacgaaaatg
     5521 tgaaagataa tgaaataaaa gactttttaa ccaaggtttc aaacttattt ttcaaggaat
     5581 tcctgatgaa acagtcaaaa acaatcaatc taaaacttgc ccactaagtg gatagaatat
     5641 tttttctgca aaacgcttga catattttta aaacatgata aaataatagt cgtaagggcg
     5701 aataaaatcg ctttcaaaca agaacaaaat gttatataag gagatttttg caaatgaaca
     5761 atcaggaaat tgcaaaaaaa gtcatcgatg ccttgggcgg acgtgaaaat gtcaatagtg
     5821 ttgcccactg tgcgactcgt ctacgtgtca tggtcaaaga tgaagagaaa atcaataaag
     5881 aagtgattga gaacttggaa aaagttcaag gtgctttctt taactcaggg caataccaaa
     5941 ttatctttgg tacaggtaca gttaacaaaa tgtacgatga agttgttgta cttggcttac
     6001 caacatcatc taaggatgac atgaaagcag aagttgctaa acaagggaac tggttccaac
     6061 gtgctatccg tactttcggt gatgttttcg ttccaatcat cccagttatc gtagcgacag
     6121 gtctcttcat gggtgtgcgt ggtcttttca acgctcttga aatgccactt ccaggtgact
     6181 ttgcaactta cacacaaatc ttgacagata cagccttcat catcttgcca ggtttggttg
     6241 tgtggtcaac cttccgtgta tttggtggaa atcctgccgt tggtatcgtt cttggtatga
     6301 tgcttgtctc tggctcactt ccaaacgctt gggcagttgc tcaaggtggt gaagtaacag
     6361 cgatgaactt ctttggtttc atccctgttg ttggtttgca aggttccgtt cttccagcct
     6421 tcatcatcgg ggttgtcgga gctaaatttg aaaaagctgt ccgcaaggtt gttccagatg
     6481 tcattgacct cttggtaaca ccattcgtga cacttttggt catgtctatc cttggactct
     6541 ttgtcattgg accagttttc cacgttgttg aaaactacat ccttattgct acaaaagcga
     6601 ttcttagcat gccatttggt cttggtggtt tcttgattgg tggggttcac caattgatcg
     6661 tcgtgtcagg tgtgcaccac atcttcaact tgcttgaagt gcaattactt gctgctgacc
     6721 atgctaaccc attcaacgct atcatcacag ctgctatgac agctcaaggt gctgctactg
     6781 ttgcggttgg tgttaaaaca aaaaatccaa aactgaaaac acttgctttc ccggctgctc
     6841 tttctgcctt cctaggtatt acagagcctg ctatcttcgg ggtgaacttg cgcttccgta
     6901 aaccattctt cctttcattg attgctggtg caatcggtgg tggattggct tctatccttg
     6961 gacttgctgg tactggtaat ggtatcacca tcatccctgg tacaatgctt tatgttggta
     7021 acggacaact tccacaatac cttcttatgg tagctgtatc atttgccctt ggttttgctc
     7081 ttacttacat gtttggttac gaagatgaag tagacgcaac tgcagctgca aaacaagctg
     7141 aagtggctga agaaaaagaa gaagttgcgc cagcagctct tcaaaatgaa acacttgtaa
     7201 ctcctatcgt cggtgatgtt gtcgctcttg ctgatgtcaa tgacccagtc ttctcaagtg
     7261 gagctatggg acaaggtatc gctgtgaaac caagtcaagg cgtggtctat gcactagctg
     7321 atgctgaagt ttcaattgcc tttccaacag ggcacgcttt tggtttgaaa acaagaaatg
     7381 gtgctgaagt tttgattcac gttggtattg acactgtatc tatgaacggt gacggttttg
     7441 aagcaaaagt tgctcaaggt aataaggtga aagctggcga tgttcttgga acatttgact
     7501 caaacaaaat cgctgcagct ggacttgatg atacaacaat ggttatcgtt acaaatacag
     7561 ctgactacgc ttcagtagct ccagtcgcaa caggttcagt ttcgaagggg gatgctgtga
     7621 tcgaagtgaa aatctaatca atcctctcta atgtgaaaac gaacaaatga catgtttgtt
     7681 cgtttttatt agatagtaag atttacagag gaaaatctaa aaaatagaga catttagact
     7741 ttcgaagtat gctataataa agaaaataaa aacaagaggt ttatcatgac aaaattatat
     7801 ggaagcttgg aagcgggcgg tacaaagttt gtctgtgctg tcggtgatga aaactttaac
     7861 gttgtagaaa aaacacaatt tccaacaaca actccaatcg agacaatcga taaaaccatt
     7921 gagttcttct caaaattcga taaccttgct ggtcttgcag ttggttcatt tgggccgatt
     7981 gatattgaca aaaactcaaa aacttatggc tttatcacga cgactccaaa accaaactgg
     8041 gcaaatgtag acttgcttgg tgcccttcgt cgcgccctaa acgtgccaat gtacttcaca
     8101 acagacgtaa acagctctgc ttacggtgaa atggttgccc gtaacaatgc tggtggtcgt
     8161 atcgaaaact tggtttacta cacaatcggt acaggtatcg gtgcaggcgt catccaacgt
     8221 ggtgagttta tcggtggtgt gggtcaccct gaaatgggtc attattatgt tgctagacac
     8281 ccaatggata ttgaaaaaga gtttaagggt gtttgtcctt tccataaggg atgtctagaa
     8341 ggttatgcag ctggtccaag tttggaagct cgtacaggtg tacgtgggga aaatattgaa
     8401 ctcaacaacc ctgtttggga tgttcaagcc tactatatcg ctcaagctgc ggttaatgcg
     8461 acagtgactt tccgcccaga cgtgattgtc tttggtggag gggtcatggc tcaacaacat
     8521 atgctggacc gtgtccgtga gaaatttaca tctcttctta atggttacct accagtacca
     8581 gatgtgcgtg actatatcgt gacgccagca gtcgcaagaa atggttctgc cacacttggg
     8641 aactttgttc ttgcaaaaga agtttcaaaa taaagcacaa aatccgcttg ggaaaccaaa
     8701 cggattttgt ggttgaaaac aatatttttg agcctttcct taagtgatta cggacggtag
     8761 cgactttctt cgaaattcca tacctaaact ttgagcctag tgtctcaaag tttccgaata
     8821 cctgaaacca ttagatttca ggtgtttcta tcacggcgga aaggctaggt aagtcctcgc
     8881 ctcactatcg aaaaatatgc ataatttcca taccaaagta tatttagtat caagctatag
     8941 ttaatctacg ctttaaaaat ccacttggga aaccaaacgg attttttacg tgtcaaagca
     9001 tttgccagaa aaagtcaata atataggtca aaccgtaggt ataaaccacg agggtaaagg
     9061 gtttggtcag aatgatgatg gtcatgtagc gcttgaaact catcttggtc agggcagcca
     9121 gcatacagag aaagtcagct gggctaatgg gccaaatcat cataaaaata aagaagcggt
     9181 caaaacgatt gcccttatct agccagccga tgtacttgtc gtaggtgcgc ttgctgacga
     9241 cagactggac aaaggcagct ccgtataggc gcactagata aaagataatg gcacagccaa
     9301 tcacgatgcc gatatagttg tagatagtcc cgatgatgtg cccgtagata aagaccccag
     9361 ccaccgaggt caaggcccct ggaatgatag ggacgacagt ctgtaaaatc tgtaaaaaga
     9421 taaagagagg tggaccccag atgcctgcct gctggataaa ggcagagagg gtttccttgg
     9481 attgtaaaat cccagcctga taagcccaaa tacagaaaat caaactccca accccaccga
     9541 caatcgatga gatattgata actcgctgca gaaggggaga aacagctttc atttgtttat
     9601 cctgtgacat gtaaactcct catagatagt atatttctac tataccatat tttggaggag
     9661 aaagggggaa tgagtctttt ttgataagga atagaaagta aatagccctt cgagacttag
     9721 aataggtctg tcaactaaag gttatatgca ttctaggttt cgaataatcg caattccata
     9781 aatttaaaag cattctaagt ttcgaatagc ttatctgaga taattttgag gcattcgcgc
     9841 tttcgaatag tcattttccc taaagtttag atgtattctg aagctagaaa gactaaaatc
     9901 taaaagtagt aagagtctct ctctgatgga cgtaatttat ggctagtatg aatcctttga
     9961 attgttagtt aattttaata ttaatcagtt ctgaaataat tactaaatat agttagatgg
    10021 tgaattaatt attgctaaat ttcaagttca agttagtcat ccagaagtct tctctggggg
    10081 acttgtagtt caagcatttt ttaggatagt tgttaatcca cttttcgatg aatgcgactt
    10141 cctttgtagt cgttttctta gttccctgag gtaaccatct atgaatgaac ttgttgtgat
    10201 ttttattaga tcctatagtg gtgtgcataa tagatatagc agattgaaac tagaatagta
    10261 tacatctact tctaaaacat tgttagaaat caatttgact gtcctgatca atttgtcctg
    10321 ttcttatttc attttactat ataatcctta gaaaacatat cggacaagcg gttgaattct
    10381 gttccgtcca ttagtagata aaggattact ccttcttgaa atgacagatg aacttgtttc
    10441 ttataaaaat gttgtctgaa actattagcc tttttccaga agttttagag gaagaaaact
    10501 ttacgaggaa aaaggagtta ctcaaataac aattcaggat taaaaataga cagttgagga
    10561 gcggaaggta taaattaagt ttgctgctgt ataatggatt tatcactaat actcttcgaa
    10621 aatctcttca aaccacgtca gcttcgcctt gccgtagata tagttactga cttcgtcagt
    10681 tctatccaca acctcaaaac agtgttttga gctgacttcg tcagttttat ctgcaacctc
    10741 aaagctgtac tttgagcagt ctacggctag cttcctagtt tgctctttga ttgtcattga
    10801 gtataaaagt gctccaggcc atattttaca cagcaatagt cttctaaaaa tggacaaaaa
    10861 acattgtaaa ggctatcaaa aaggagtata atgagtgcaa gaaatttcgg aggtgaaaga
    10921 tgctagaagt aagaagtcta gagaaaagtt ttggatccaa gcaagttttg tttggtattg
    10981 actttcaagc gcgaccaggt cgtattttgg gactagtcgg aaaaaatggt gctggaaaaa
    11041 caacgatttt ccatagtatt ttaaaattcc tagaatatca gggagaaatc ggtctggatg
    11101 gtcaggatat tcgtcaggag acctatgctc ggattggtta tctgcctgaa gaacgcagtc
    11161 tcatgcctaa attgacagtt cttgaacaag ttcgctactt ggcgactcta aaaggcatgg
    11221 atgccaaaga agtcaaagaa aaactccctc aatggatgaa gaggttggaa gtgaaaggaa
    11281 agctgacaga taaaatcaag agtctgtcaa aaggaaatca gcagaagatt cagctcatta
    11341 ttactctgat tcatgaacca gacctgatta tcttggatga gccttttagt ggattggacc
    11401 cagttaatac agaattgctc aaacaagtca tttttcagga aaaagagcgc ggagcaacca
    11461 ttatcttttc tgaccatgtc atgaccaatg ttgaggaact ttgtgacgat attctgatga
    11521 tccgagatgg ccgtgtggtc ttgcacggac caattcagga tgtccgcaat caatacggga
    11581 aaacgcgtct ctttgtttca agtgaacgaa gcaaggaaga attggaaaat cttcctcatg
    11641 tcaaacaggt gagcttgacc aaacaaggca gttggaaatt gattttggag gatgagagcg
    11701 ctggaaggga actcttccca atcttgactc aaggtcaata tatcgcaaca tttgaccaac
    11761 aagcgccaac tatcgatgaa atctttaaac tagaatcagg agtggaagta tgagaaatat
    11821 gtgggttgta atcaaggaaa cctatcttcg acatgtcaag tcatggagtt tcttctttat
    11881 ggtgatttcg ccgttcctct ttttaggaat ctctgtagga attgggcata tccaaggttc
    11941 ttctatggct aaaaataata aagtggcagt agtgacaaca gtgccatctg tagcagaagg
    12001 actgaagaat gtaaatggtg ttaacttcga ctataaagac gaagcaagtg ccaaagaagc
    12061 aattaaagaa gaaaaattaa aaggttattt gaccattgat caagaagata gtgttctaaa
    12121 ggcagtttat catggcgaaa catcgcttga aaatggaatt aaatttgagg ttacaggtac
    12181 actcaatgaa ctgcaaaatc agcttaatcg ttcaactgct tccttgtctc aagagcagga
    12241 aaaacgctta gcgcagacaa ttcaattcac agaaaagatt gatgaagcca aggaaaataa
    12301 aaagtttatt caaacaattg cagcaggtgc cttaggattc tttctttata tgattctgat
    12361 tacctatgcg ggtgtaacag ctcaggaagt tgccagtgaa aaaggcacca aaattatgga
    12421 agtcgttttt tctagcataa gggcaagtca ctatttctat gcgcggatga tggctctgtt
    12481 tctagtgatt ttaacgcata ttgggatcta tgttgtaggt ggtctggctg ccgttttgct
    12541 ctttaaagat ttgccattct tggctcagtc tggtattttg gttcacttgg gagatgctat
    12601 ctcactgaat accctgctct ttattttgat cagtcttttc atgtacgtag tcttggcagc
    12661 cttcctagga tctatggctt ctcgtcctga ggactcaggg aaagccttgt cgcctttgat
    12721 gattttgatt atgggtggtt tttttggagt gacagctcta ggtgcagctg gtgacaatct
    12781 cctcttgaag attggttctt atattccctt tatttcgacc ttctttatgc cgtttcgaac
    12841 gattaatggc tatgcggggg gagcagaagc atggatttca cttgctatta cagtgatttt
    12901 tgcggtggta gcaacaggat ttatcggacg catgtatgct agtctcgttc ttcaaacgga
    12961 tgatttaggg atttggaaaa cctttaaacg tgccttatct tataaataga agagccttgc
    13021 gaaagcgagg tttttaaagg tgaaaagggt ggaatcacga acctaattat gtacacatta
    13081 tgtaaacagg ttgcttgaaa actcaattgt atagtgaact gaatctggaa taggataata
    13141 ttacttctaa aacattctta taaattgatt tgaattccaa aatcccatcg ttccgttctt
    13201 atttcatttt gcgatatagc gaaaggaaat aagtcagctc acaaaaaacg cataatatca
    13261 aggattttta acacttgata ctatgcgttt tctaatttta aagacttttt gcctggtctc
    13321 ttttgttcta tgagtatgtt acatatctag gtaaaaatta tttaaagcaa attaacctta
    13381 tttctcaaga tgtagtaggt tccgagataa aagatagcta tgaatatgag ttctttaaca
    13441 atggctatac ctgctcccat atagaaatgg tcattgagtc ctaccagtga attgacatag
    13501 aaattggaac taagattgaa gaaaagttca ataaatccaa tgacgatttg gataccaatg
    13561 taggctgcaa cagcgagtgc tgtacggtat tcattgaaaa gctgtccaat ggaaatagcc
    13621 aggtagatgc agaggattcc tgaaatggta tttagtagga aggatatacc tgtaagaaag
    13681 atctgaggga gatgtgtttc tacaaatgta atcacataag aaagaggaat ccattctgga
    13741 gctgttaaag ccagaataat aacagcactt agagccaata cagcggtgct aatcaatgac
    13801 cagataaagg caccgattag tttggctgtg atgatatggt gttcagaaac tggcaaggtc
    13861 aaagtcagat agccttgtcg gtcgtagaca ctacctttga agcgtttaat aatcaagaaa
    13921 atggttgaaa tcgcaagtgt aagcatcaag ccaccaaaga ctgtagctag aaaaagtagc
    13981 atagtagcct gactttcttg gtaaggtaga tttttaaagc cttgtgtctg tattccgatg
    14041 agggcagaaa ggactagcac ggctgcgtag agggctaaat accacttgtt aacattttta
    14101 aattcgtagt gaactaaatt ccaaaacata aataatctcc tttgcttagg ccttaaattc
    14161 ctgacggaag agttggtcaa tggattcacc tgactcgtag cgaatatcat ctacatttcc
    14221 ttgacggacg acttttccgt cttttaggaa gacaatttca tccaagattg gctcgatatc
    14281 agaaatcaag tgggtagaaa tcaaaacggt agaagttggt gagtagttgt tgataatggt
    14341 attgaggata taagcacggg ctgctggatc caccccacca atgggttcat ccaaaacata
    14401 gagacgagca tcacggctca taaccaaaat cagttgaacc ttttctttgt ttccttttga
    14461 tagtttcttg agacgactat tttcatcaat gcccaggtct gcaagtagat gatgggcgcg
    14521 ttcaagattg aaatctttat agaaggtctt gaagtaggtt agggcttctt tgaccttcat
    14581 ttgctcattg agataggtcg tatcaggcaa ataagctaca acggccttgg ttgctgggct
    14641 tgggtccatg tcgttgatga ggacacgtcc ttgatctggt tgtaagaggc cattaattag
    14701 tttaatcagg gttgtttttc ctgagccgtt tggcccaaga aggccgacaa tttttccagc
    14761 tggaatgtca agagaaacat tttcaagggc tggtgttgct ccatatgatt tggatacatt
    14821 ttcaaatgct agtaatgaca taggcttaaa ctcctttaat ataatcactg actacgcctg
    14881 gtagttcttc tttttcatag ccaaaatggg tcatggagga aacgaagtgt tccaattctt
    14941 cttctgataa ttgtttgcgt gactgagcga ttagctcctt atccttagtc acaaatcgtc
    15001 cagttgttcg cttgctgtag acaaatcctt ctcgttcaag gtctgataag gctctttgga
    15061 tggtattggg attgacacca gcctcgctag ctagctccct cacggttgga agttgttgat
    15121 tgggttccag tgtatgggaa acaatctgaa gcttgatttt ctccataatc tgtaaataga
    15181 tgggtttttt gttgtcaaat gtccaggaca tcttagtctc ctttctttta ccttgttgtc
    15241 ttaattaaat aatacaacaa aacaaaaaac ttgtcaagca aaaagaagaa ttgttttggg
    15301 aatcgcttaa aaaatggtat aatgaaaaga aaacgataag gagggaaagg atgcgttgtc
    15361 caaaatgtgg ggctaccaag tcaagtgtta tcgatagtcg ccaagcagaa gaagggaaca
    15421 ccattcgtag aagacgtgag tgcgacgaat gccaacaccg ttttacaacc tacgaacgag
    15481 tagaagaaag aaccttagtg gttgttaaaa aagatggcac acgggaacaa ttctccagag
    15541 ataaaatctt taatgggatt atccgctcag cccagaaacg tcctgtgtca agtgatgaaa
    15601 tcaacatggt agtcaatcgt atcgaacaga aactccgtgg tcgaaatgaa aatgaaattc
    15661 aaagtgagga cattggttca ctcgtcatgg aggagttggc tgaattggac gagattacct
    15721 atgtacgttt tgctagtgtc tatcgtagtt ttaaggatgt cagtgagtta gagagcttgc
    15781 tccaacaaat cacccagtcc tctaaaaaga aaaaggaaag ataaatgaag ccaattgacc
    15841 gtttttctta tctaaagaat aatcgggtgt cgcaagatac ctcatctctg gtacagtgct
    15901 acctcccgat tatcggtcag gaggcactga gcctttatct ttatacaatc agtttttggg
    15961 ataatggtag aaaggaatat cttttttcaa gcattctcaa ccatctcaac tttgggatgg
    16021 atagactgat aaaatcattg aaaatcttat ctgcttttaa tctcttgacc ctctatcaaa
    16081 agggtgatgt ttatcagcta gccctccatg ctcctctatc tagtcaagac ttcttggggc
    16141 atcctgttta tcgcagactc ttagagaaaa agattggcga tgtagctgtg gaggatttga
    16201 aagttgaaag tgctgatggt gaagaaatac ctgtctcact caatcaagtc tttccagaat
    16261 tggcagaact aggcagtcaa gaagaccttg gtctcaagaa gaaagtggcc aatgattttg
    16321 acttggaaca ttttcgccag ctgatggctc gagatggact tcgttttgcg gatgagcagt
    16381 ccgatgtctt aaacctcttt gctattgccg aggagaagaa atggacttgg tttgaaacct
    16441 atcaattggc caagtcaaca gctgtttccc aggttatttc aaccaaacgc atgcgtgaaa
    16501 aaattgctca aaaaccagtt tcctctgact ttagtcttaa ggaagcgacc attatcaaag
    16561 aagctaaaag taaaactgcc ctgcagttct tagcagaaat caagcaaaca cgcaagggaa
    16621 ccattaccca aacagaaaga gaactcttgc aacagatggc tggcttgggc ttactggacg
    16681 aagtcatcaa tattattctc ttattgacct ttaataaggt ggattcggca aatatcaatg
    16741 agaaatatgc catgaaggta gccaatgact atgcctatca aaagattcat tcggcagaag
    16801 aggccgtttt acgaattcgt gatcgagggc agaaagcaaa aacacaaaaa cagaatcaga
    16861 ctgccccaga aaaaaccaat gttcctaaat ggagtaatcc tgaatataag aatgaaacca
    16921 gcgaggaaac tcgtctggaa ctagaacgta agaagcaaga actattagct cgattagaaa
    16981 aaggaggaga ttagatggaa agtgtcggag acgtactcaa acgtcaaccc agccgttttt
    17041 attatcaaga tttggtccag aaaatcatga aggaccctga tgttgcggcc tttatccagc
    17101 aagaatcctt aactccaaag gaattaaatc gcagtatctc caagtttaat cagtacatca
    17161 ccgagcgtga caagtttctc cgtggggata cggattatat tgccaaaggc tacaagccga
    17221 ttttggttaa gaatcatggt tatgcagatg tttcatatga agaaactcct gagctaatcg
    17281 cggctgaaaa agaagcggct attaagaacc gtctcaagtt aatcaatcta ccagccagtc
    17341 tcaagaaagc tagtttggct caagttgact tggatgattt ggggcgctta ccagtttttg
    17401 aaaagctact agccttcgtg gagcaatatc cagctattcg aaaaggtctt tacttatatg
    17461 gagactttgg tgtgggtaaa agtttcatgg tggcggcctt agctcatgat ttatcagaaa
    17521 aacgtggtgt ttcatcaact ctcctccact atcctagctt tgtcattgat gtcaaaaatg
    17581 ctatcagtga tggcaatgtt aagaccttgg tggatgagat taagctgtct gaggtcctga
    17641 ttttagatga tattggcgcc gagcaatcaa ccgtttgggt gcgtgacgaa atcctgcagg
    17701 tcattctcca atatcggatg caggaaaatt taccgacctt tttcacatcc aacttcaact
    17761 ttgaagattt ggagaagcat tttgcgaaag tgaaacatgg aaatgacgaa acctgggaag
    17821 ccagacgggt catggaacgc atccgttatt tggctgagga gactcgttta gaaggagtaa
    17881 accgtcgatg acagaaacca ttaaattgat gaaggctcat acttcagtgc gcaggtttaa
    17941 agagcaagaa attccccaag tagacttaaa tgagattttg acagcagccc agatggcatc
    18001 atcttggaag aatttccaat cctactctgt gattgtggta cgaagtcaag agaagaaaga
    18061 tgccttgtat gaattggtac ctcaagaagc cattcgccag tctgctgttt tccttctctt
    18121 tgtcggagat ttgaaccgag cagaaaaggg agcccgactt cataccgaca ccttccaacc
    18181 ccaaggtgtg gaaggtctct tgattagttc ggtcgatgca gctcttgctg gacaaaacgc
    18241 cttgttggca gctgaaagct tgggctatgg tggtgtgatt atcggtttgg ttcgatacaa
    18301 gtctgaagaa gtggcagagc tctttaacct acctgactac acctattctg tctttgggat
    18361 ggcactgggt gtgccaaatc aacatcatga tatgaaaccg agactgccac tagagaatgt
    18421 tgtctttgag gaagaatacc aagaacagtc aactgaggca atccaagctt atgaccgtgt
    18481 tcaggctgac tatgctgggg cgcgtgcgac cacaagctgg agtcagcgcc tagcagaaca
    18541 gtttggtcaa gctgaaccaa gctcaactag aaaaaatctt gaacagaaga aattattgta
    18601 gaaagtgaga aattatggcc ctaccaacta ttgccattgt aggacgtccc aatgttggga
    18661 aatcaaccct atttaatcgg atcgctggtg agcgaatctc cattgtagaa gatgtcgaag
    18721 gagtgacacg tgaccgtatt tatgcaacgg gtgagtggct caatcgttct tttagcatga
    18781 ttgatacagg aggaattgat gatgtcgatg ctcctttcat ggaacaaatc aagcaccagg
    18841 cagaaattgc catggaagaa gcagatgtta tcgtttttgt cgtgtctggt aaggaaggaa
    18901 ttactgatgc agacgaatac gtagctcgta agctttataa gacccacaaa ccagttatcc
    18961 tcgcagtcaa caaggtggac aaccctgaga tgagaaatga tatatatgat ttctatgctc
    19021 tcggtttggg tgaaccattg cctatctcat ctgtccatgg aatcggtaca ggggatgtgc
    19081 tagatgcgat cgtagaaaat cttccaaatg aatatgagga agaaaatcca gatgtcatta
    19141 agtttagctt gattggtcgt cctaacgttg gaaaatcaag cttgatcaat gctatcttgg
    19201 gagaagaccg tgttattgct agtcctgttg ctggaacaac tcgtgatgcc attgataccc
    19261 actttacaga tacagatggt caagagttta ccatgattga tacggctggt atgcgtaagt
    19321 ctggtaaggt ttatgaaaat actgagaaat actctgttat gcgtgccatg cgtgctattg
    19381 accgttcaga tgtggtcttg atggtcatca atgcggaaga aggcattcgt gagtacgaca
    19441 agcgtatcgc aggatttgcc catgaagctg gtaaagggat gattatcgtg gtcaacaagt
    19501 gggatacgct tgaaaaagat aaccacacta tgaaaaactg ggaagaagat atccgtgagc
    19561 agttccaata cctgccttac gcaccgatta tctttgtatc agctttaacc aagcaacgtc
    19621 tccacaaact tcctgagatg attaagcaaa tcagcgaaag tcaaaataca cgtattccat
    19681 cagctgtctt gaacgatgtc atcatggatg ccattgccat caacccaaca ccgacagaca
    19741 aaggaaaacg tctcaagatt ttctatgcga cccaagtggc aaccaaacca ccaacctttg
    19801 tcatctttgt caatgaagaa gaactcatgc acttttctta cctgcgtttc ttggaaaatc
    19861 aaatccgcaa ggcctttgtt tttgagggaa caccgattca tctcatcgca agaaaacgca
    19921 aataaaaaag tagaatctgg aatgacagtt ccggattttt ttgatataat aaaataatag
    19981 aaaacgctat caaaagaagg ggggatgtcg gtgatggaac atttgtttaa attcttactt
    20041 ttagcaccgt acttttattt tgataactgg attgaaaagg ccaacagaaa tagtaagttt
    20101 tttccaattt tttattattt ttactggttt tacatcccct tctattctct ttttagcctt
    20161 gcttggacag ttgtttcagt tctgtttttc aataccgtct tgagaaatgt gacagatatc
    20221 aagttatggg gcatttggtt tctttttatt ctgctagcta ttggtatgaa ttggttaact
    20281 tattcctgtt tcaaagaaat gtttcgcttg agacaggaac tagggaagtc taagggtgga
    20341 aggcattgat ttatatcggt ttctatttgt aggaggtggc ttatggtacc tctaaaatca
    20401 tttattacac gctattccaa ggtttatatt ggtaataaca tttaatagaa cgaaactaaa
    20461 gaaaataatt taaaagagga ggtttgtgat ggaacacttg tttaaaatga taatcttatt
    20521 accctgtttt tactttttca gctggattga caaggataat agagaaagta aatttttccc
    20581 aattttttac tatttttact ggatttacat caccctctat gctcttttta gccttgcttg
    20641 gacagttttt tcagttctgt ttttcaatat cgtcttgaga aatttgacag atatcaagtt
    20701 atggggtatt tggctattat tactacttat cgcttttgct agtgactggt tagcctatgt
    20761 ctttttcaaa aaaatgcttg acttgagacg ggaactaggg aagtctaaag gcggaaggca
    20821 ttgatttata ctcttcgaaa atctcttcaa accacgtcaa cgtcgccttg gattatatat
    20881 gtaactgact tcgtcagtct tatctacaac ctcaaagcag tgctttgagc aacttgcagc
    20941 tagtttccta gtttgctctt tgattttcat tgagtattat attactttct atttgtagga
    21001 ggtggcttat gaagattcct ctcttaactt ttgcaaggca taaatttgtt tatgtcttgc
    21061 ttactttgct ttttcttgct ttggtttatc gtgatgtttt gatgacttat ttcttttttg
    21121 atattcatgc gcccgatcta gctaaattcg atggacaagc aattaaaaat gacttattaa
    21181 aatcagcatt agattttcgt attctccagt tcaatctagg tttttatcaa tcatttatta
    21241 ttccaatcat cattgttttg ctaggttttc aatatattga gctgaaaaat aaagttttac
    21301 gattgagtat tggaagagaa gtgagttatc aagggttaaa aagaaagttg actttgcaag
    21361 ttgcaagtat cccttgtttg atatatttag tgactgtgct gataattgca attataacct
    21421 atttctttgg gactttttct cctcttggat ggaattctct attttctgat ggaagtggtt
    21481 tacaaagact cctagatgga gagataaaaa gctatttgtt ctttacttgt gtcctactaa
    21541 tcggtatttt catcaatgca atctattttt tacaaatagt tgattatgtg gggaatgtga
    21601 ctcgttcggc aatcacctat ttgatgtttc tttggcttgg ttctatgctg ctttatagtg
    21661 ccttgcctta ctatatggtt cctatgacga gtttgatgca agctagctat ggggatgtaa
    21721 gtttgatgaa actctttact ccttatatcc tttatattgt cccttacatg gtgcttgaaa
    21781 aatatgaaga taatgtttaa gaattttaac aatattttgc taaatagaaa gattgtttta
    21841 ctacttcgta tagttctgat gatgattttg ataaaccatc tattgtcaac agcggttcaa
    21901 aagcaggatg ctgttatctt tttcaagaga gaattgattt caattttttc ctataatgac
    21961 tattctgaag cgaatttaga aatccccaaa ctattgttaa acctttcgct tttcatggta
    22021 ggatggctct ctgtcatttt acttgaaagt gatttggcag accattacca tcacttgatt
    22081 cgctatcaat caagctcctt tttcgattat acaaggaaac gattggttgt catttctaaa
    22141 ttttttactc aagatttgtt tgtctggttt cttggtttac ttcctctagg aattcatttc
    22201 aaaacagtcg cacttttctt tttacttgct cagttaatga tgttgtactt actactgtct
    22261 tatctgatag cactgattag tgcgggcgct ggtttttcct tttttctcta ttttttagca
    22321 tttgtgggac aagaatggat gatggatcat attgtaacag tgtatttagt actcttaagt
    22381 ttattagtta tgttgattgt tagtcgcttg gaagagaaat ttaagaaagg ataaacgatg
    22441 agacttgaaa ttataaatgg acagaaaatt tatgggaaaa gacctatttt aaatcagttg
    22501 aatttggtgt ttcaatcagg aaaaatttat ggacttaaag gtgataatgg atctggcaag
    22561 acggttcttt taaagatact tgctggttat attaagcttg acaaaggaaa agttcttcaa
    22621 gatggtaaag tttacggggt aaaaaatcat tatattcagg atgcaggaat tttaattgaa
    22681 aaagtcgagt ttttatctca tttatccctg agagaaaatt tggaactgtt aaggtatttt
    22741 tcatctaaag ttacggaaaa aagaattgcc tattggattc aatactatga tttacaggaa
    22801 tttgaagaca ttgaataccg tcatttatcc ttaggaacaa agcaaaaaat ggccttgatt
    22861 caagccttta tttcctctcc ttctatactc tttctcgatg aacctatgaa tgctttggat
    22921 gagaagagtg tgaggttaac caaacaggtc attttatctt acctgaaaaa agaaaatggt
    22981 ctggttatcc tgacgtcgca catatcggaa gatatttcag acctttgtac agatgtatta
    23041 gttgtcgaaa atggacatat acaaatgtaa aggatataca atcctaggag atggcttatg
    23101 gcacatctaa aatcatttat tacacgatat tccaaggttt atattggttt agttctgctg
    23161 atctggctgt ctttcttctt tatcccttgg gataaaccac ttctggggat aaggattgac
    23221 atcttcatca tacagaaaat cttgctagct tttggaattc tgtccattct catggccttg
    23281 ctgtccaaga aagtcagtct ctttgttttt ggactgattt gctgtctttc tctttggatt
    23341 aacttattta tcacatttgc cattttgccg atttttggca attaaacagt cataaaagtc
    23401 ggagaggtta gcttgaaaac taacctcttt ttccttttca aaatggggat tcttccttga
    23461 aaataatcag taattgtgct aaaattaaag gaacattcta aaatattcgg aatttaaagt
    23521 aaggaaaaac atggctaata ttttaaaaac aattatcgaa aatgataaag gagaaatccg
    23581 tcgtctggaa aagatggctg acaaggtttt caaatacgaa gaccaaatgg ctgctttgac
    23641 tgacgaccaa ctaaaagcaa aaacagttga atttaaggaa cgttatcaaa atggagaatc
    23701 actggattca ttgctttacg aagcatttgc ggttgtccgt gaaggtgcca aacgtgtcct
    23761 aggtctcttc ccttataagg ttcaggtcat gggggggatt gttcttcacc atggtgacgt
    23821 gccagagatg cgtacagggg aagggaaaac cttgactgcg accatgccgg tatacctcaa
    23881 tgccctttca ggtaaagggg ttcacgtagt tacggttaat gaatacctgt cagaacgtga
    23941 cgcgactgag atgggtgaat tgtactcttg gcttggtttg tcagtaggga ttaacttggc
    24001 taccaaatct ccaatggaga aaaaagaagc ctatgagtgt gatattactt actcaactaa
    24061 ctcagaaatc ggatttgact accttcgtga caacatggtc gttcgcgccg aaaacatggt
    24121 acaacgtccg cttaactatg ccttggtcga tgaggttgac tctatcttga ttgacgaggc
    24181 tcgtacacct ttgattgtat caggtgccaa tgcggttgaa accagtcagt tgtatcacat
    24241 ggcagaccac tatgtaaaat ctttgaacaa agatgactac atcatcgatg tgcagtctaa
    24301 gactattggt ttgtctgatt cagggattga cagggctgaa agctacttca aacttgaaaa
    24361 cctctatgac atcgaaaacg tggctttgac tcactttatc gataacgccc ttcgtgccaa
    24421 ctacatcatg cttctcgata ttgactatgt ggtgagcgaa gagcaagaaa tcttgattgt
    24481 cgaccaattt acaggtcgta ccatggaagg tcgtcgttat tctgatggat tgcaccaagc
    24541 tattgaagcc aaagaaggtg tgccaatcca ggatgaaacc aagacatctg cctcaatcac
    24601 gtaccaaaac ctcttccgta tgtacaagaa attgtctggt atgacgggta caggtaagac
    24661 tgaggaagaa gaattccgtg aaatctacaa cattcgtgtt attccaatcc caacaaaccg
    24721 tcctgttcaa cgtattgacc actcagacct tctttatgca agtatcgaat ctaagtttaa
    24781 agcggttgtc gaagacgtta aggctcgtta ccaaaagggt caacctgtct tggttggtac
    24841 agtagcggtt gaaactagtg actacatttc taagaaattg gttgcagctg gtgttcctca
    24901 cgaagtcttg aatgccaaaa accactatag agaagcccaa atcatcatga atgctggtca
    24961 acgtggtgcc gttaccatcg caaccaacat ggcgggtcgt ggtaccgaca tcaagcttgg
    25021 tgaaggtgtt cgtgaacttg gaggactttg tgttattggt acagaacgtc atgaaagtcg
    25081 tcgtatcgat aaccagcttc gtggacgttc aggtcgtcaa ggagatccag gtgagtcaca
    25141 attctaccta tctcttgaag atgatttgat gaaacgtttt ggttctgaac gcttgaaggg
    25201 aatctttgaa cgcttgaaca tgtctgaaga ggccattgag tctcgcatgt tgacgcgtca
    25261 ggttgaagca gctcagaaac gtgtcgaagg aaataactac gatacccgta aacaagtcct
    25321 tcaatacgat gatgtcatgc gtgaacaacg tgagattatc tatgctcaac gttacgatgt
    25381 catcactgca gatcgtgact tggcacctga aattcagtct atgatcaaac gcacgattga
    25441 acgtgtcgtt gatggtcatg cgcgtgccaa acaagatgaa aaactagagg caattttgaa
    25501 ctttgctaag tacaacttgc ttcctgaaga ttctattacg atggaagact tgtcaggctt
    25561 gtctgataag gccatcaagg aagagctttt ccaacgttcc ttgaaggttt acgatagtca
    25621 ggtttcaaaa ctacgcgatg aagaagcagt taaagaattc caaaaagttt tgattctacg
    25681 agtggtggat aacaagtgga cagatcatat cgatgccctt gatcaattgc gtaacgcggt
    25741 tggacttcgt ggctatgctc agaacaaccc tgttgttgag tatcaggcag aaggtttccg
    25801 tatgtttaat gatatgattg gttcgattga gtttgatgtg acacgcttga tgatgaaagc
    25861 acaaattcat gaacaagaaa gaccacaggc agaacgtcat atcagtacaa cagcgactcg
    25921 caatatcgct gctcaccaag caagtatgcc agaagatttg gatttgagcc agattggacg
    25981 caatgaactt tgcccatgtg gttctggtaa gaaatttaaa aactgtcacg gtaaaagaca
    26041 ataaaatgag atagtttaga ggcggatatc ttgtgaaaag taaattttta ctgggtatcc
    26101 gtttgcttta taaggagatg agttatggta tttacagcaa aaagctctaa aataaatata
    26161 gaagaagttc gtgccttgtc aaaattagaa ggtcaggctt tggagaggaa atcacagcga
    26221 gatcaagagc tagaagccat tatacgtgga gaagaccagc gaattctctt ggtaatcggg
    26281 ccatgctcat ctgacaacga agaagctgtc cttgaatacg ctaagcgttt ggcagtccta
    26341 caagaagaag tggcagatcg tatctttatg gttatgcgtg tttatactgc caaaccccgt
    26401 accaacggag atggctataa gggcttgatt caccagccta acgcgacaga agcgcctagt
    26461 cttatcaatg gaatcaaagc cgttcgccat cttcactatc gtgtcatcac agaaacaggg
    26521 atgacaactg ctgatgaaat gctttatcct gaaaaccttc cgcttgtaga tgatttgatt
    26581 tcttacatgg cagttggtgc ccgttcagtt gaagaccagc aacaccgctt tgtggcaagt
    26641 ggggcaggat tttctactgg ttttaaaaat ccaacctctg gaaatctcaa tgtcatgttt
    26701 aatgggattt atgctgctca aaacaaacaa agtttccttt tcttaggaaa agaagtagaa
    26761 acaactggga acccgctttc acacgctatt cttcgtggtg ctcttaatga gtatggaaaa
    26821 aatattccca actactatta tgacaattta attgatacca ttgcccagta tgagaaaatg
    26881 ggcttggaaa atccttttat catcattgat accaatcatg acaattctgg taagcagtat
    26941 attgaacaga tccgaattgt ccgccagacc ttgattaacc gtgcttggaa tgaaaaaatt
    27001 aagcagttcg ttcgtggttt tatgattgag tcttatctgg aagatggtcg acaaaatgag
    27061 ccagaagtat ttggtaagtc tatcacagac ccttgcctgg gttgggataa cacagaagct
    27121 cttgtcagag aaatttacaa aacgttagga gaataagatg gcatttattg aaaaaggtca
    27181 agaaatcgat atggaagtca tcaaggctga aacccaattg tctgcggaag ccttgagact
    27241 caaggaaagc cgtgacaggg aattggcaga tattatttca ggggaagatg accgtattct
    27301 cttggtgatt ggtccttgct cttctgataa tgaagaggcg gtcttggaat atgctcgccg
    27361 tttatctgcc ttgcaaaaga aggtagcgga taagattttc atggtcatgc gcgtgtatac
    27421 tgctaagcct cgtaccaatg gagacggcta taaaggatta gttcaccagc cagatacttc
    27481 taaggctcca agcctgatta atggcttgca ggctgtgcgc cagttgcact accgcgtgat
    27541 tacagagact ggtttgacaa cggcagatga gatgctttat ccgtcaaatc tgatcttggt
    27601 ggatgacttg gtcagctacc atgccgttgg agctcgttct gtggaagacc aagagcaccg
    27661 ctttgtggct tctgggattg atgcaccagt agggatgaaa aatccaacct caggaaattt
    27721 gggtgttatg tttaacgcca tctatgctgc tcaaaacaag caaaccttcc tttatcatgg
    27781 gcaggaagtt gagacatcag gtaatccttt ggcccatgtt atcctccgtg gagcagtcaa
    27841 cgagtatggc aattatatgc cgaattacta ctatgaaaat ctactccaag ccattgaacg
    27901 ctatgaaacc atgggacttg aaaatccttt tatcctcatt gacaccaacc atgataactc
    27961 aggcaagcaa tatatggagc agattcgaat tgttcgccag accttgcaga atcgtgattg
    28021 gaatgagaaa attaaaaaga cggttcgagg atttatgatt gaatcttacc tagcagatgg
    28081 tcgtcaaaac caaccagaga tctttggttg ctctattact gacccttgcc taggttggga
    28141 aaatacagag gccttggtag aagagattta tgttaccttg acaaaataag tgaaaaggat
    28201 ggagttgggg aatctcaact ccttttgatg agaatgatag ttggacacgg aattgacatc
    28261 gaagaattgg cttcgataga aagcgcagtt acacgacatg aaggatttgc taagcgtgta
    28321 ctgaccgctc aggaaatgga gcgcttcacc agtctcaaag gacgcaggca aatagaatat
    28381 ttagctggtc gctggtcggc taaggaggcc ttttccaagg ctatgggaac gggcattagc
    28441 aagctcggtt ttcaggattt ggaagtcttg aacaatgaac gtggggcgcc ttattttagt
    28501 caggcaccat tttcaggaaa gatttggctg tctatcagcc acaccgatca gtttgtgaca
    28561 gccagtgtca ttttggagga aaatcatgaa agctagtcca catagaccaa ccaaggctct
    28621 gattcatctg ggagctattc gacaaaatat tcagcaaatg ggggctcata tccctcaagg
    28681 aacgctcaag ttggctgtgg ttaaggccaa tgcttatggt catggagctg ttgccgttgc
    28741 caaggcaatt caagatgatg ttgatggctt ttgcgtttcc aatatcgatg aagccattga
    28801 actcagacaa gctggactca gcaagccaat cctcatttta ggagtttctg aaatcgaagc
    28861 tgttgctcta gctaaagaat atgacttcac cttgacagtg gctggactgg agtggattca
    28921 agcactctta gataaggaag tggacctaac tggattgaca gtccacctca agattgattc
    28981 agggatggga cggattggtt ttagagaggc aagtgaggtt gagcaggctc aagatttgct
    29041 ccaacaacac ggtgtttgtg ttgaaggaat ctttacccac tttgctactg ctgatgagga
    29101 atcagatgac tattttaatg cccagttaga acggtttaaa actattttag ctagtatgaa
    29161 ggaagttcca gagctggttc atgctagcaa ttctgcaacg actctttggc atgtagagac
    29221 tattttcaat gcggttcgta tgggagatgc catgtatggc ctcaatccaa gtggagcggt
    29281 cttggatttg ccttatgatt tgataccggc cttgaccttg gagtctgctc tggttcatgt
    29341 caagacagtt ccagctggag cttgcatggg ctatggagca acttatcaag cggatagcga
    29401 gcaagtcatc gcgaccgtgc caatcgggta tgcagatgga tggacaagag acatgcaaaa
    29461 tttctctgtc ttggtagatg gccaagcttg cccaattgtc ggcagggttt cgatggacca
    29521 aatcactatt cgattgccta agctttatcc gctaggaacc aaggtaacct tgattggctc
    29581 caatggggat aaggaaatca ctgcaactca ggtagcgacc taccgcgtaa ccattaacta
    29641 tgaggtggtt tgcctcctca gcgaccgtat tccgagagaa tattattaga aaagaaagga
    29701 gtggagcatg aatctacatc aacccttgca tgtcttgcct ggtgtgggac caaagtcagc
    29761 agaaaaatac gccaaactag gaattgaaaa cttgcaagat ctcttgctct actttccttt
    29821 ccgttatgaa gacttcaaaa ccaagcaggt gctggagctg gaagacggtg agaaggcagt
    29881 tctttctggt caggtagtga ctcctgctag tgtccagtat tatggtttca agcgcaatcg
    29941 cctgcgtttt agtctcaagc agggagaggt cgtttttgcg gtgaatttct ttaaccagcc
    30001 ctatctggct gataaaatag agttgggagc aacccttgct gtctttggaa aatgggactg
    30061 cgctaaggct agtctgactg ggatgaaggt tctggctcag gtagaagatg acctccagcc
    30121 tgtctatcgt ctggctcagg gaatcagtca ggccagtctg gtcaaggtca tcaagacggc
    30181 ttttgatcag ggactggacc tcttgataga agaaaatctg ccccagtctt tactagacaa
    30241 atacaaactc atgtcccgtt gtcaggcagt ccgtgctatg cattttccaa agtatttggc
    30301 agaatacaag caggctcttc gccgtataaa gtttgaggaa ctcttttatt tccaaatgca
    30361 gctgcagatg ctcaagtctg aaaatagagt tcagggaagt ggtctggttc tgaattggtc
    30421 tcaggaaaaa gtgacagcag ttaaagtaag tcttcctttt gccctgaccc aagctcagga
    30481 aaagagtttg caggaaattt taactgatat gaagtccgac caccacatga atcgtctcct
    30541 acaaggggat gtggggagtg gaaaaacggt agtcgctggc ttggccatgt ttgcggcagt
    30601 gacagcaggt tatcaggctg ccctaatggt accaacagaa atcctcgcag agcaacactt
    30661 tgagagttta cagaaccttt ttcccaattt gaaactggct ctcttgacag gttccttgaa
    30721 agctgcagaa aagagagaag tcttggagac cattgccaag ggtgaggctg atttgattat
    30781 aggaactcac gctctgatac aagatggggt ggagtatgct cgtcttggtt tgattattat
    30841 cgatgagcag caccgttttg gtgtagggca aaggcgtatt ttacgggaaa aaggtgacaa
    30901 tccagatgtc ctcatgatga cggcgactcc cattccacgg acgcttgcca tcacagcctt
    30961 tggagatatg gatgtttcca ttatcgacca gatgccagca ggtcggaagc ctattgtgac
    31021 gcgctggatc aaacatgagc aactacctca ggtcttgact tggttagagg gggaaattca
    31081 aaaaggttcc caagtctatg tcatctctcc tttgattgaa gaatcagaag ctctagattt
    31141 gaaaaatgcc attgccttat cagaggagtt gacgactcat tttgcaggca aggcagaggt
    31201 ggctcttcta catggtagga tgaagagtga cgaaaaagac cagatcatgc aggatttcaa
    31261 ggagagaaag acggatattc tggtttcgac gacggttatt gaggttgggg tcaacgttcc
    31321 caatgcgact gtcatgatta tcatggatgc cgatcgcttc ggtctcagtc aacttcacca
    31381 gcttagaggt cgtgtcggtc ggggggacaa gcagtcctac gctgttctcg ttgctaatcc
    31441 caagacggat tctgggaaag accgcatgcg tatcatgaca gaaacgacca atggatttgt
    31501 ccttgcggag gaagatttga aaatgcgtgg ttctggtgag atttttggaa ccagacagtc
    31561 aggacttcca gagttccaag tggctgatat tatcgaagat tttccgattt tagaagaagc
    31621 aagaaaggtt gctagctaca ttagttctat agaagcttgg caagaagatc cagagtggcg
    31681 catgattgcc cttcatctgg aaaagaaaga acatctggat taagctttct ctaaggaaaa
    31741 cttatactca atgaaaatca aagagcaaac taggaagcta accgcaggtt gctcaaaaca
    31801 ctgttttgag gttgtggatg aaactgacga agtcagctca aaacaccgtt ttgaggtggc
    31861 agatagaact gacgaagtca gtaacatata tatacggtaa ggcgacgctg acgtggtttg
    31921 aagagatttt cgaagagtat taagctagtt tttaggtttg gctcttatac tagagtcatc
    31981 aaaaagaaac gaggactctc atatgacagt aacgattaaa gtaaattacc aaaccacttt
    32041 ccaaaagaag gaagcaaaaa actagtataa acagaagaga gagcgaaatg ctcttttttc
    32101 gtttctaaaa ctactttcag cccatcatcc taaaagtaaa gaatctaaat tcactttcta
    32161 tttacccttc tttcttgcat tgattacata gatatgctac agttgtggta acgattacaa
    32221 aataaaagga gcatgctatg aaaaatccag ctttgctaga agaaattaag acctatagag
    32281 gaagggatga ggttccggaa gactttgatg atttctggga tggggaagtg aaaaatgttt
    32341 ccacgcttcc atcctaccac ttggaggaaa gagatttcca cattcctcaa gtcaagtgct
    32401 atgagttaac atttgaagga agcaaggaag gaaaggtcta tgcacgcatt gttcttccaa
    32461 agagtgagga gaaggtccca ttaatcttcc attttcatgg ttatatggga cgtggctggg
    32521 actgggccga catgctgggc ttcaccgtag ctggttacgg tgttgtttcc atggatgtgc
    32581 ggggccagtc aggttactca caagacggct tgcgttctcc tttaggaaat accgtgaagg
    32641 ggcatattat ccgtggtgct gtggaaggtc gggaccacct cttttataag gatgtttatc
    32701 tggatattta ccagttggtc gaaattgttg ctagtctgtc tcaggttgat gagaagcgtc
    32761 tttctagcta tggtgcctca caaggagggg ctctagctct agttgcagca gcgctcaatc
    32821 ctcgaattca gaaaacagtt gccatttatc ccttcttgtc agacttcaga cgggtgattg
    32881 agattggtaa tactagcgag gcttacgacg aacttttccg ttatttcaag tttcacgacc
    32941 ccttccatga aacagaggag gaaatcatgg cgacccttgc ctatatcgat gtcaaaaatc
    33001 ttgcccatcg tatccaaggt gaggttaaga tgattacggg cttggacgac gatgtttgct
    33061 atcccattac ccagtttgcg atttataatc gtctgacctg cgataaaacc tatcgcatca
    33121 tgcctgagta tgctcacgaa gccatgaatg tatttgtcaa tgaccaagtc tacaactggc
    33181 tctgtggaag tgagattcct tttaaatatc taaaataagg agtcgactct aagcacaaaa
    33241 tcttaaaaat tacaaacacg catagtatca ggggattaag aaaactttat actatgcgtt
    33301 ttatcatgga aatatagtaa aatgaaataa gaacaggaca aatcgatcag gacagtcaaa
    33361 tcgatttcta acaatgtttt agaaacaaat gtgtactatt ctagtgtcaa tctattatat
    33421 ttatagaatt ttttgttgct agatttgtca aattgcttaa aataattttt ttcagaaagc
    33481 aaaagccgat acctatcgag tagggtagtt cttgctatcg tcaggcttgt ctgtaggtgt
    33541 taatactttt caaaaatctc ttcaaaccac gtcagcttcg ccttgccgta tatatgttac
    33601 tgacttcgtc agttctatct gccacctcaa aacaccgttt tgagcatcat gcggctagct
    33661 tcttagtttg ctctttgatt ttcattgagt ataaaaacag atgagtttct gttttctttt
    33721 tatggactat aaatgttcag ctgaaactac tttcaaggac attattatat aaaagaattt
    33781 tttgaaacta aaatctacta tattacacta tattgaaagc gttttaaaaa tgaggtataa
    33841 taaatttact aacgcttata aaaagtgata gaatctattt ttatgtatat ttaaagatag
    33901 attgctgtaa aaatagtagt agctatgcga aataacagat agagagaagg gattgaagct
    33961 tagaaaaggg gaataatatg atatttaagg cattcaagac aaaaaagcag agaaaaagac
    34021 aagttgaact acttttgaca gtttttttcg acagttttct gattgattta tttcttcact
    34081 tatttgggat tgtccccttt aagctggata agattctgat tgtgagcttg attatatttc
    34141 ccattatttc tacaagtatt tatgcttatg aaaagctatt tgaaaaagtg ttcgataagg
    34201 attgagcagg aagtatggtg taaatagcat aggctgatgt ccatcatttg cttataaaga
    34261 gatattttag tttaattgca gcggtgtcct ggtagataaa ctagattggc aggagtctga
    34321 ttggagaaag gagaggggaa aattggcacc aatttgagat agtttgttta gttcattttt
    34381 gtcatttaaa tgaactgtag taaaagaaag ttaataaaag acaaactaag tgcattttct
    34441 ggagtaaatg tcttatttca gaaatcggga tatagatata gagaggatca gtatgaatcg
    34501 gagtgttcaa gaacgtaagt gtcgttatag cattaggaaa ctatcggtag gagcggtttc
    34561 tatgattgta ggagcagtgg tatttggaac gtctcctgtt ttagctcaag aaggggcaag
    34621 tgagcaacct ctggcaaatg aaactcaact ttcgggggag agctcaaccc taactgatac
    34681 agaaaagagc cagccttctt cagagactga actttctggc aataagcaag aacaagaaag
    34741 gaaagataag caagaagaaa aaattccaag agattactat gcacgagatt tggaaaatgt
    34801 cgaaacagtg atagaaaaag aagatgttga aaccaatgct tcaaatggtc agagagttga
    34861 tttatcaagt gaactagata aactaaagaa acttgaaaac gcaacagttc acatggagtt
    34921 taagccagat gccaaggccc cagcattcta taatctcttt tctgtgtcaa gtgctactaa
    34981 aaaagatgag tacttcacta tggcagttta caataatact gctactctag aggggcgtgg
    35041 ttcggatggg aaacagtttt acaataatta caacgatgca cccttaaaag ttaaaccagg
    35101 tcagtggaat tctgtgactt tcacagttga aaaaccgaca gcagaactac ctaaaggccg
    35161 agtgcgcctc tacgtaaacg gggtattatc tcgaacaagt ctgagatctg gcaatttcat
    35221 taaagatatg ccagatgtaa cgcatgtgca aatcggagca accaagcgtg ccaacaatac
    35281 ggtttggggg tcaaatctac agattcggaa tctcactgtg tataatcgtg ctttaacacc
    35341 agaagaggta caaaaacgta gtcaactttt taaacgctca gatttagaaa aaaaactacc
    35401 tgaaggagcg gctttaacag agaaaacgga catattcgaa agcgggcgta acggtaaccc
    35461 aaataaagat ggaatcaaga gttatcgtat tccagcactt ctcaagacag ataaaggaac
    35521 tttgatcgca ggtgcagatg aacgccgtct ccattcgagt gactggggtg atatcggtat
    35581 ggtcatcaga cgtagtgaag ataatggtaa aacttggggt gaccgagtaa ccattaccaa
    35641 cttacgtgac aatccaaaag cttctgaccc atcgatcggt tcaccagtga atatcgatat
    35701 ggtgttggtt caagatcctg aaaccaaacg aatcttttct atctatgaca tgttcccaga
    35761 agggaaggga atctttggaa tgtcttcaca aaaagaagaa gcctacaaaa aaatcgatgg
    35821 aaaaacctat caaatcctct accgtgaagg agaaaaggga gcttatacca ttcgagaaaa
    35881 tggtactgtc tatacaccag atggtaaggc gacagactat cgcgttgttg tagatcctgt
    35941 taaaccagcc tatagcgaca agggtgatct atacaagggt gaccaattac taggaaatat
    36001 ctacttcaca acaaacaaaa cttctccatt tagaattgcc aaggatagct atctatggat
    36061 gtcctacagt gatgacgacg ggaagacatg gtcagctcct caagatatta ctccgatggt
    36121 caaagccgat tggatgaaat tcttgggtgt aggtcctgga acaggaattg tacttcggaa
    36181 tgggcctcac aagggacgga ttttgatacc ggtttatacg actaataatg tatctcactt
    36241 agatggctcg caatcttctc gtgtcatcta ttcagatgat catggaaaaa cttggcatgc
    36301 tggagaagcg gtcaacgata accgtcaggt agacggtcaa aagatccact cttctacgat
    36361 gaacaataga cgtgcgcaaa atacagaatc aacggtggta caactaaaca atggagatgt
    36421 taaactcttt atgcgtggtt tgactggaga tcttcaggtt gctacaagta aagacggagg
    36481 agtgacttgg gagaaggata tcaaacgtta tccacaggtt aaagatgtct atgttcaaat
    36541 gtctgctatc catacgatgc acgaaggaaa agaatacatc atcctcagta atgcaggtgg
    36601 accgaaacgt gaaaatggga tggtccactt ggcacgtgtc gaagaaaatg gtgagttgac
    36661 ttggctcaaa cacaatccaa ttcaaaaagg agagtttgcc tataattcgc tccaagaatt
    36721 aggaaatggg gagtatggca tcttgtatga acatactgaa aaaggacaaa atgcctatac
    36781 cctatcattt agaaaattta attgggaatt tttgagcaaa aatctgattt ctcctaccga
    36841 agcgaaagtg aagcgaacta gagagatggg caaaggagag atgggcaaag gagttattgg
    36901 cttggagttc gactcagaag tattggtcaa caaggctcca acccttcaat tggcaaatgg
    36961 taaaacagcg actttcctaa cccagtatga tagcaagacc ttgttgtttg cagtagataa
    37021 ggaagatatc ggacaggaaa ttattggtat agctaaagga agcatcgaaa gtatgcataa
    37081 tcttcctgta aatctagcag gtgccagagt tcctggcgga gtaaatggta gcaaagcagc
    37141 ggtgcatgaa gttccagaat ttacaggggg agttaatggt acagagccag ctgttcatga
    37201 aatcgcagag tataagggat ctgattcgct tgtaactctt actacaaaaa aagattatac
    37261 ttacaaagct cctcttgctc agcaggcact tcctgaaaca ggaaacaagg agagtgacct
    37321 cctagcttca ctaggactaa cagctttctt ccttggtctg tttacgctag ggaaaaagag
    37381 agaacaataa gagaagaatt ctaaacattt gattttgtaa aaatggctct ttgtcaactg
    37441 tagtgggttg aagtcagcta agctcgagaa aggacaaatt ttgtcctttc ttttttgata
    37501 ttcagagcga taaaaatccg ttttttgaag ttttcaaagt tccgaaaacc aaaggcattg
    37561 cgcttgataa gtttgatgag attattggtc gcttccaatt tggcgttaga atagtgtagt
    37621 tgaagggcgt tgacgatttt ctctttgtcc tttagaaagg ttttaaagac agtctgaaaa
    37681 agaggatgaa cctgctttag attgtcctca atgagtccga aaaatttctc cggttcctta
    37741 ttctgaaagt gaaacagcaa gagttgatag agctgatagt gatgtttcaa gtcttgtgaa
    37801 tagctcaaaa gcttgtttaa aatctcttta ttggttaaat gcatacgaaa agtagggcga
    37861 taaaaatgtt tatcgctgag tttacgacta tcctgttgta tgagcttcca gtagcgcttg
    37921 atagccttgt attcatgaga ctttcgatcc aattgattca tgatttgaac acgcacacga
    37981 ctcatagcac ggctaagatg ttgtacaatg tgaaagcgat ccaacacgat tttagcacat
    38041 gggaaaagtt gt
//
LOCUS       DBEJAU010000013        36808 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC323 isolate 683620
            SAMN38261939-rid24807223.denovo.013, whole genome shotgun sequence.
ACCESSION   DBEJAU010000013 DBEJAU010000000
VERSION     DBEJAU010000013.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261939
            Sequence Read Archive: SRR26833919
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 36808)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 36808)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576303.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576303.1
            Genome Coverage       :: 154x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/19/2025 01:05:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,121
            CDSs (total)                      :: 2,078
            Genes (coding)                    :: 1,943
            CDSs (with protein)               :: 1,943
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 36
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 72 of 135
            Pseudo Genes (incomplete)         :: 63 of 135
            Pseudo Genes (internal stop)      :: 51 of 135
            Pseudo Genes (multiple problems)  :: 46 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..36808
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261939-rid24807223.denovo.013"
                     /strain="GPSC323"
                     /isolate="683620"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            1..1248
                     /locus_tag="ACL29Z_000740"
                     /pseudo
     CDS             1..1248
                     /locus_tag="ACL29Z_000740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611513.1"
                     /note="frameshifted; internal stop; incomplete; missing
                     N-terminus; Derived by automated computational analysis
                     using gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
     gene            complement(1376..2398)
                     /gene="cbpF"
                     /locus_tag="ACL29Z_000741"
     CDS             complement(1376..2398)
                     /gene="cbpF"
                     /locus_tag="ACL29Z_000741"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000771060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline-binding protein CbpF"
                     /protein_id="HGR0069081.1"
                     /translation="MKLLKKMMQVALATFFFGLLGTSTVFADDSEGWQFVQENGRTYY
                     KKGDLKETYWRVIDGKYYYFDPLSGEMVVGWQYIPAPHKGVTIGPSPRIEIALRPDWF
                     YFGQDGVLQEFVGKQVLEAKTATNTNKHHGEEYDSQAEKRVYYFEDQRSYHTLKTGWI
                     YEEGHWYYLQKDGGFDSRINRLTVGELARGWVKDYPLTYDEEKLKAAPWYYLDPVTGI
                     MQTGWQYLGNKWYYLHSSGAMATGWYKEGSTWYYLDTENGDMRTGWQYLGNKWYYLRS
                     SGAMATGWYQEGSTWYYLNASNGDMKTGWFQVNGNWYYAYDSGALAVNTTVGGYYLNY
                     NGEWVK"
     gene            complement(2417..3238)
                     /gene="cbpG"
                     /locus_tag="ACL29Z_000742"
     CDS             complement(2417..3238)
                     /gene="cbpG"
                     /locus_tag="ACL29Z_000742"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001100143.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline-binding protein CbpG"
                     /protein_id="HGR0069082.1"
                     /translation="MNVEGRGSANFIKDNVLITAAHNYYRHDYGKEADDIYVLLAVSP
                     SQEPFGKIKVKEVRYLKEFRNLNSKDAREYDLALLILEKPIGAKLGTLGLPTSQKNLT
                     GITVTITGYPSYNFKIYQMYTDKKQVLSDDGMFLDYQVDTLERSSGSAVYDASHRVVG
                     VHTLGDGANQINSAVKLNERNLSFIYSVLKGYSLEGWKKINGSWYYYRQHDKQTGWQE
                     INDTWYYLDSSGKMLTDWQKVNGNWYYLNSNGAMVTGSQTIDGKVYNFASSGEWI"
     gene            complement(3319..3558)
                     /locus_tag="ACL29Z_000743"
     CDS             complement(3319..3558)
                     /locus_tag="ACL29Z_000743"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000754500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0069083.1"
                     /translation="MKKTVYKKLGISIIASTLLASQLSTVSALSVISSTGEEYEVSET
                     LEKGPGSNDSSLSEISPTYGSYYQKQSEVLSVMMI"
     gene            complement(3708..4477)
                     /locus_tag="ACL29Z_000744"
                     /pseudo
     CDS             complement(3708..4477)
                     /locus_tag="ACL29Z_000744"
                     /inference="COORDINATES: protein motif:HMM:NF020296.4"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DNA alkylation repair protein"
     gene            complement(4478..5110)
                     /locus_tag="ACL29Z_000745"
     CDS             complement(4478..5110)
                     /locus_tag="ACL29Z_000745"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000698412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HGR0069084.1"
                     /translation="MKILLVDDHEMVRLGLKSYFDLQDDVEVVGEASNGSQGIDLALE
                     LRPDVIVMDIVMPEMNGIDATLAILKEWPEAKILIVTSYLDNEKIMPVLDAGAKGYML
                     KTSSADELLHAVSKVAAGELAIEQEVSKKVEYHRNHMELHEELTARERDVLQLIAKGY
                     ENQRIADDLFISLKTVKTHVSNILAKLEVSDRTQAAVYAFQHHLVGQDEF"
     gene            complement(5124..6119)
                     /locus_tag="ACL29Z_000746"
     CDS             complement(5124..6119)
                     /locus_tag="ACL29Z_000746"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000743650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HGR0069085.1"
                     /translation="MKKQAYVIIALTSFLFVFFFSHSLLEILDFDWSIFLHDVEKTEK
                     FVFLLLVFSMSITCLLALFWRGIEELSLRKMQANLKRLLAGQEVVQVADPDLDASFKS
                     LSGKLNLLTEALQKAENHSLAQEEEIIEKERKRIARDLHDTVSQELFAAHMILSGISQ
                     QALKLDREKMQIQLQSVTAILETAQKDLRVLLLHLRPVELEQKSLIEGIQILLKELED
                     KSDLRVSLKQNMTKLPKKIEEHIFRILQELISNTLRHAQASCLDVYLYQTDVELQLKV
                     VDNGIGFRLGSLDDLSYGLRNIKERVEDMAGTVQLLTAPKQGLAVDIRIPLLDKE"
     gene            complement(6116..6814)
                     /gene="liaF"
                     /locus_tag="ACL29Z_000747"
     CDS             complement(6116..6814)
                     /gene="liaF"
                     /locus_tag="ACL29Z_000747"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001224647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-active antibiotics response protein
                     LiaF"
                     /protein_id="HGR0069086.1"
                     /translation="MRKFKIFLFIEACLLTGALILMVSEHFSRFLLILFLFLLLIRYY
                     TGKEGNNLLLVAATILFFFIVMLNPFVILAIFVAVIYSLFLLYPMMNQEKEQTNLVFE
                     EVVTVKKEKNRWFGNLHHFSSYQTCQFDDINLFRFMGKDTIHLERVILTNHDNVIILR
                     KMVGTTKIIVPVDVEVSLSVNCLYGDLTFFNQPKRALRNEHYHQETKDYLKSNKSVKI
                     FLTTMIGDVEVVRG"
     gene            complement(6892..7902)
                     /gene="fni"
                     /locus_tag="ACL29Z_000748"
     CDS             complement(6892..7902)
                     /gene="fni"
                     /locus_tag="ACL29Z_000748"
                     /EC_number="5.3.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000210649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004452 - isopentenyl-diphosphate
                     delta-isomerase activity [Evidence IEA];
                     GO_function: GO:0010181 - FMN binding [Evidence IEA];
                     GO_process: GO:0008299 - isoprenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type 2 isopentenyl-diphosphate Delta-isomerase"
                     /protein_id="HGR0069087.1"
                     /translation="MTTNRKDEHILYALEQKSSYNSFDEVELIHSSLPLYNLDEIDLS
                     TEFAGRKWDFPFYINAMTGGSNKGREINQKLAQVAESCGILFVTGSYSAALKNPTDDS
                     FSVKSSHPNLLLGTNIGLDKPVELGLQTVEEMNPVLLQVHVNVMQELLMPEGERKFRS
                     WQSHLADYSKQIPVPIVLKEVGFGMDAKTIERAYEFGVRTVDLSGRGGTSFAYIENRR
                     SGQRDYLNQWGQSTMQALLNAQEWKDKVELLVSGGVRNPLDMIKCLVFGAKAVGLSRT
                     VLELVETYTVEEVIGIVQGWKADLRLIMCSLNCATIADLQKVDYLLYGKLKEAKDQMK
                     KA"
     gene            complement(7886..8893)
                     /locus_tag="ACL29Z_000749"
     CDS             complement(7886..8893)
                     /locus_tag="ACL29Z_000749"
                     /EC_number="2.7.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000562378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004631 - phosphomevalonate kinase
                     activity [Evidence IEA];
                     GO_process: GO:0016126 - sterol biosynthetic process
                     [Evidence IEA];
                     GO_process: GO:0019287 - isopentenyl diphosphate
                     biosynthetic process, mevalonate pathway [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphomevalonate kinase"
                     /protein_id="HGR0069088.1"
                     /translation="MIAVKTCGKLYLAGEYAILEPGRLALIKDIPIYMRAEIAFSDSY
                     RIYSDMFDFAVDLRPNPDYSLIQETIALMGDFLAVRGQNLRPFSLEICGKMEREGKKF
                     GLGSSGSVVVLVVKALLALYDVSVDQELLFKLTSAVLLKRGDNGSMGDLACIVAEDLV
                     LYQSFDRQKAAAWLEEENLATVLERDWGFFISQVKPTLECDFLVGWTKEVAVSSHMVQ
                     QIKQNINQNFLTSSKETVVSLVEALEQGKSEKIIEQVAVASKLLEGLSTDIYTPLLRQ
                     LKEASQDLQAVAKSSGAGGGDCGIALSFDAQSTKTLKNRWADLGIELLYQERIGHDDK
                     S"
     gene            complement(8880..9833)
                     /gene="mvaD"
                     /locus_tag="ACL29Z_000750"
     CDS             complement(8880..9833)
                     /gene="mvaD"
                     /locus_tag="ACL29Z_000750"
                     /EC_number="4.1.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000373478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005829 - cytosol [Evidence IEA];
                     GO_function: GO:0004163 - diphosphomevalonate
                     decarboxylase activity [Evidence IEA];
                     GO_process: GO:0019287 - isopentenyl diphosphate
                     biosynthetic process, mevalonate pathway [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="diphosphomevalonate decarboxylase"
                     /protein_id="HGR0069089.1"
                     /translation="MDREPVTVRSYANIAIIKYWGKKKEKEMVPATSSISLTLENMYT
                     ETTLSPLPANVTADEFYINGQLQNEVEHAKMSKIIDRYRPAGEGFVRIDTQNNMPTAA
                     GLSSSSSGLSALVKACNAYFKLGLDRSQLAQEAKFASGSSSRSFYGPLGAWDKDSGEI
                     YPVETDLKLAMIMLVLEDKKKPISSRDGMKLCVETSTTFDDWVRQSEKDYQDMLIYLK
                     ENDFAKIGELTEKNALAMHATTKTASPAFSYLTDASYEAMAFVRQLREKGEACYFTMD
                     AGPNVKVFCQEKDLEHLSEIFGQRYRLIVSKTKDLSQDDCC"
     gene            complement(9815..10693)
                     /gene="mvk"
                     /locus_tag="ACL29Z_000751"
     CDS             complement(9815..10693)
                     /gene="mvk"
                     /locus_tag="ACL29Z_000751"
                     /EC_number="2.7.1.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000163319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004496 - mevalonate kinase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0016126 - sterol biosynthetic process
                     [Evidence IEA];
                     GO_process: GO:0019287 - isopentenyl diphosphate
                     biosynthetic process, mevalonate pathway [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="mevalonate kinase"
                     /protein_id="HGR0069090.1"
                     /translation="MTKKVGVGQAHSKIILIGEHAVVYGYPAISLPLLEVEVTCKVVS
                     AESPWRLYEEDTLSMAVYASLEYLDITEACVRCEIDSAIPEKRGMGSSAAISIAAIRA
                     VFDYYQADLPHDVLEILVNRAEMIAHMNPSGLDAKTCLSDQPIRFIKNVGFTELEMDL
                     SAYLVIADTGVYGHTREAIQVVQNKGKDALPFLHALGELTQQAEVAISQKDAEGLGQI
                     LSQAHLHLKEIGVSSPEADFLVETTLSHGALGAKMSGGGLGGCIIALVTNLTHAQELA
                     ERLEEKGAVQTWIESL"
     gene            complement(10815..11144)
                     /locus_tag="ACL29Z_000752"
     CDS             complement(10815..11144)
                     /locus_tag="ACL29Z_000752"
                     /inference="COORDINATES: protein motif:HMM:NF024736.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HGR0069091.1"
                     /translation="MTRKVYDTDLNDQEWAKIEPYFSKHRTYKWPKRVLVNETLYVTK
                     TGCQWRMLPHDFPLYLMVWSFFRRSMTTGWFQVNGRWYYAYSSGALAVNTTVDGYFVN
                     YNGEWVQ"
     gene            11755..12630
                     /locus_tag="ACL29Z_000753"
     CDS             11755..12630
                     /locus_tag="ACL29Z_000753"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014632445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0031179 - peptide modification [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="lanthionine synthetase LanC family protein"
                     /protein_id="HGR0069092.1"
                     /translation="MYPPELDSKILSIIKKAVTIRTTHTYEYQYSLLFGDAGYLWLLL
                     HLFSISKNQYYLQLANVTAKKLIENYDTLEEIDFALGKSGVLLSLIKYYQFTNDNTLK
                     IFIHNSIGEIYHYFLQRDTAKESILDYSFAHGYCGIAYALFAYSKVLEPSMFYNDLHT
                     FHTELKKLLEKVTSNTENLGNLQLSWCKGISGIILYLCMYDCDGNKDIISKYQEFVFN
                     HHLKMMTGYCHGITSLLQTTVYNQNKLLMKKIQQVILACSERDDHGLLMFQGDSGKAD
                     LFDFGIGSMGYIGVY"
     gene            12673..13905
                     /locus_tag="ACL29Z_000754"
     CDS             12673..13905
                     /locus_tag="ACL29Z_000754"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000765682.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HGR0069093.1"
                     /translation="MKLFWTNNIYRQLLLNSCFSSFGDSIFYLAIINYVAQYNFAPLA
                     ILLISISEMVPLLSQLFLGILGDFQENRVKHALWIAKIKILLYAILTVFLVLSPFSLV
                     SVIMIVIINLISDTLSYLSAYMMNALYISVIKDDLHDAMGFRQSLMRVVRIVANLAGA
                     FLINVISIQTISLINTLTFVIAFLGLYVIRHTLYEVEKRIEMSHTALSFKKYFQHLKQ
                     SLAVLLRLKDTVILLFLTTSMIAILDVSPRLIALRFIQQTLAQLSIGQLLALLSIIMS
                     CGAILGNMTSSNLFKNIRFTHLLVFCEISLLTLITSILCQAYIVIFMTSFISSTIIGI
                     LSPRLQAAVFAHIPSDKMGTVGSALSTVDILAPSLLSLLALSIASGVSVQLALIFLYL
                     ILIALIFCQWLVKFNTHN"
     gene            complement(14023..15021)
                     /gene="cbpJ"
                     /locus_tag="ACL29Z_000755"
     CDS             complement(14023..15021)
                     /gene="cbpJ"
                     /locus_tag="ACL29Z_000755"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000698047.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline-binding protein CbpJ"
                     /protein_id="HGR0069094.1"
                     /translation="MKLLKKTMQAGLTVIFFGLLATNTVFADNSEVWQFVQENGRTYY
                     KKGDLKETYWRVIDGKYYYFDSLSGEMVVGWQYIPFPSKGSTIGPYPNGIRLEGFPKS
                     EWYYFDKNGVLQEFVGWKTLEIKTKDSVGRKYGEKREDSEDKEEKRYYTNYYFNQNHS
                     LETGWLYDQSNWYYLAKTEINGENYLGGERRAGWINDDSTWYYLDPTTGIMQTGWQYL
                     GNKWYYLRSSGAMATGWYQEGTTWYYLDQPNGDMKTGWQNLGNKWYYLRSSGAMVTGW
                     VKDDSTWYYLNAGNGDMKTGWFQVNGRWYYAYSSGALAVNTTVDGYSVNYNGEWVR"
     gene            complement(15040..16062)
                     /gene="cbpC"
                     /locus_tag="ACL29Z_000756"
     CDS             complement(15040..16062)
                     /gene="cbpC"
                     /locus_tag="ACL29Z_000756"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000771084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline-binding protein CbpC"
                     /protein_id="HGR0069095.1"
                     /translation="MKLLKKMMPIALAVFFFGLLATSTVFADTMGGRFVDKDNRKYYV
                     KDDHKAIYWHKIDGKTYYFGDIGEMVVGWQYLEIHGTGYRDDLFDNRPVFEIGLQEKW
                     YYFGQDGALLEQTDKQVLEAKTSENTGKVYGEQYPLSAEKKTYYFDNNYAVKTGWIYE
                     DGNWYYLNKLGNFGDDSYNPLPIGEVAKGWTQDFHVTIDIDRSKPAPWYYLDASGKML
                     TDWQKVNGKWYYFGSSGSMATGWKYVRGKWYYLDNKNGDMKTGWQYLGNKWYYLRSSG
                     AMVTGWYQDGSTWYYLDAENGDMKIGWTKVNGKWYYLNSSGAMVTGSQTIDGKVYNFA
                     SSGEWI"
     gene            complement(16161..16850)
                     /locus_tag="ACL29Z_000757"
     CDS             complement(16161..16850)
                     /locus_tag="ACL29Z_000757"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000518023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HGR0069096.1"
                     /translation="MGKRILLLEKERNLAHFLSLELQKEQYRVDLVEEGQKALSMALQ
                     TDYDLILLNVNLGDMMAQDFAEKLSRTKPASVIMILDHWEDLQEELEVVQRFAVSYIY
                     KPVFIENLVARISAIFRGRDFIDQHCSLMKVPRTYRNLRIDVEHHTVYRGEEMIALTR
                     REYDLLATLMGSKKVLTREQLLESVWKYESATETNIVDVYIRYLRSKLDVKGQKSYIK
                     TVRGVGYTMQE"
     gene            complement(16862..18286)
                     /gene="gndA"
                     /locus_tag="ACL29Z_000758"
     CDS             complement(16862..18286)
                     /gene="gndA"
                     /locus_tag="ACL29Z_000758"
                     /EC_number="1.1.1.44"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004185725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004616 - phosphogluconate dehydrogenase
                     (decarboxylating) activity [Evidence IEA];
                     GO_function: GO:0050661 - NADP binding [Evidence IEA];
                     GO_process: GO:0006098 - pentose-phosphate shunt [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-dependent phosphogluconate dehydrogenase"
                     /protein_id="HGR0069097.1"
                     /translation="MTKANFGVVGMAVMGRNLALNIESRGYTVAIYNRSKEKTEDVIA
                     CHPEKNFVPSYDVESFVNSIEKPRRIMLMVQAGPGTDATIQALLPHLDKGDILIDGGN
                     TFYKDTIRRNEELANSGINFIGTGVSGGEKGALEGPSIMPGGQKEAYELVSDVLEEIS
                     AKAPEDGKPCVTYIGPDGAGHYVKMVHNGIEYGDMQLIAESYDLMQHLLGLSAEDMAE
                     IFTEWNKGELDSYLIEITADILSRKDDEDQDGPIVDYILDAAGNKGTGKWTSQSSLDL
                     GVPLSLITESVFARYISTYKEERVHASKVLPKPAAFNFEGDKAELIEKIRQALYFSKI
                     ISYAQGFAQLRVASKENNWNLPFADIASIWRDGCIIRSRFLQKITDAYNRDADLANLL
                     LDEYFLDVTAKYQQAVRDIVALAVQAGVPVPTFSAAITYFDSYRSADLPANLIQAQRD
                     YFGAHTYQRKDKEGTFHYSWYDEK"
     gene            complement(18362..19756)
                     /gene="mapZ"
                     /locus_tag="ACL29Z_000759"
     CDS             complement(18362..19756)
                     /gene="mapZ"
                     /locus_tag="ACL29Z_000759"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000039255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mid-cell-anchored protein MapZ"
                     /protein_id="HGR0069098.1"
                     /translation="MSKKRRNRHKKEGQEPQFDFDEAKELTVGQAIRKNEEVEAGVLP
                     EDSILDKYVKQHRDEIEADKFATRQYKKEEFVETQSLDDLIQEMREAVEKSEASSEEV
                     PSSEDILLPLPLDDEEQGLDPLLLDDENPTEMTEEVEEEQNLSRLDQEDSEKKSKKGF
                     ILTVLALVSVIICVSAYYVYRQVNRSTKEIETSQSTTANQSDVDDFNTLYDAFYTDSN
                     KTALKNSQFDKLSQLKTLLDKLEGSREHTLAKSKYDSLATQIKAIQDVNAQFEKSAIV
                     DGVLDTNAKAKSDAKFTDIKTGNTELDKVLDKAISLGKSQQTSTSSSSSSQTSSSSSS
                     QASSNTTSEPKPSSSNETRSSRSEVNMGLSSAGVAVQRSASRVAYNQSAIDDSNNSAW
                     DFADGVLEQILATSRSRGYITGDQYILERVNIVNGNGYYNLYKPDGTYLFTLNCKTGY
                     FVGNGAGHADDLDY"
     gene            complement(19769..20926)
                     /locus_tag="ACL29Z_000760"
     CDS             complement(19769..20926)
                     /locus_tag="ACL29Z_000760"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000711388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent RNA methyltransferase"
                     /protein_id="HGR0069099.1"
                     /translation="MKKEFNLIATVAAGLEAVVGREVRELGYDCQVENGRVRFQGDVR
                     AIIETNLWLRAADRIKIIVGTFPAKTFEELFQGVFALDWENYLPLGARFPISKAKCVK
                     SKLHNEPSVQAISKKAVVKKLQKHYARPEGVPLMENGPEFKIEVSILKDVATVMIDTT
                     GSSLFKRGYRTEKGGAPIKENMAAAILQLSNWYPDKTLIDPTCGSGTFCIEAVMIARK
                     MAPGLRRSFAFEEWNWISDRLIQEVRTEAAKKVDRELELDIMGCDIDARMVEIAKANA
                     QAAGVAGDITFKQMRVQDLRSDKINGVIISNPPYGERLSDDAGVTKLYAEMGQVFAPL
                     KTWSKFILTSDEAFESKYGSQADKKRKLYNGTLKVDLYQYFGQRVKRQEVK"
     gene            complement(21011..21391)
                     /gene="rnpB"
                     /locus_tag="ACL29Z_000761"
     ncRNA           complement(21011..21391)
                     /ncRNA_class="RNase_P_RNA"
                     /gene="rnpB"
                     /locus_tag="ACL29Z_000761"
                     /product="RNase P RNA component class B"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00011"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00011"
     gene            complement(21412..21741)
                     /gene="gpsB"
                     /locus_tag="ACL29Z_000762"
     CDS             complement(21412..21741)
                     /gene="gpsB"
                     /locus_tag="ACL29Z_000762"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000146522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division regulator GpsB"
                     /protein_id="HGR0069100.1"
                     /translation="MASIIFSAKDIFEQEFGREVRGYNKVEVDEFLDDVIKDYETYAA
                     LVKSLRQEIADLKEELTRKPKPSPVQAEPLEAAITSSMTNFDILKRLNRLEKEVFGKQ
                     ILDNSDF"
     gene            complement(21811..22338)
                     /locus_tag="ACL29Z_000763"
     CDS             complement(21811..22338)
                     /locus_tag="ACL29Z_000763"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000179549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1273 domain-containing protein"
                     /protein_id="HGR0069101.1"
                     /translation="MATALVLGYSAFDLGLFSDKDPRLKLIKKAIRKDLEAMAADGVS
                     WLVFTGSLGFEYWVLEVAQEMKTEYGFQLATIFAFETHGENWNEGNQMKLSRFKQVDF
                     VKYAYPRYEHKGQLRDYQQFLLENTTSSYLFYDEENETKLAYFYQKMKNQEDYFIKRL
                     TFDQLNELAENFSEN"
     gene            22404..23000
                     /gene="recU"
                     /locus_tag="ACL29Z_000764"
     CDS             22404..23000
                     /gene="recU"
                     /locus_tag="ACL29Z_000764"
                     /EC_number="3.1.21.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000248773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction resolvase RecU"
                     /protein_id="HGR0069102.1"
                     /translation="MVNYPHKVSSQKRQTSLSQPKNFANRGMSFEKMINATNDYYLSQ
                     GLAVIHKKPTPIQIVQVDYPQRSRAKIVEAYFRQASTTDYSGVYNGYYIDFEVKETKQ
                     KRAIPMKNFHPHQIQHMEQVLAQQGICFVLLHFSSQQETYLLPAFDLIRFYHQDKGQK
                     SMPLEYIREYGYEIKAGAFPQIPYLNVIKEHLLGGKTR"
     gene            22997..25156
                     /gene="pbp1a"
                     /locus_tag="ACL29Z_000765"
     CDS             22997..25156
                     /gene="pbp1a"
                     /locus_tag="ACL29Z_000765"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001040003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008658 - penicillin binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein PBP1A"
                     /protein_id="HGR0069103.1"
                     /translation="MNKPTILRLIKYLSISFLSLVIAAIVLGGGVFFYYVSKAPSLSE
                     SKLVATTSSKIYDNKNQLIADLGSERRVNAQANDIPTDLVKAIVSIEDHRFFDHRGID
                     TIRILGAFLRNLQSNSLQGGSTLTQQLIKLTYFSTSTSDQTISRKAQEAWLAIQLEQK
                     ATKQEILTYYINKVYMSNGNYGMQTAAQNYYGKDLNNLSLPQLALLAGMPQAPNQYDP
                     YSHPEAAQDRRNLVLSEMKNQGYISAEQYEKAVNTPITDGLQSLKSASNYPAYMDNYL
                     KEVINQVEEETGYNLLTTGMDVYTNVDQEAQKHLWDIYNTDEYVAYPDDELQVASTIV
                     DVSNGKVIAQLGARHQSSNVSFGINQAVETNRDWGSTMKPITDYAPALEYGVYDSTAT
                     IVHDEPYNYPGTNTPVYNWDRGYFGNITLQYALQQSRNVPAVETLNKVGLNRAKTFLN
                     GLGIDYPSIHYSNAISSNTTESDKKYGASSEKMAAAYAAFANGGTYYKPMYIHKVVFS
                     DGSEKEFSNVGTRAMKETTAYMMTDMMKTVLTYGTGRNAYLAWLPQAGKTGTSNYTDE
                     EIENHIKTSQFVAPDELFAGYTRKYSMAVWTGYSNRLTPLVGNGLTVAAKVYRSMMTY
                     LSEGRNPEDWNIPEGLYRNGEFVFKNGARSTWSSPAPQQPPSTESSSSSSDSSTSQSS
                     STTPSTNNSTTTNPNNNTQQSNTTPDQQNQNPQPAQP"
     gene            complement(25323..30626)
                     /locus_tag="ACL29Z_000766"
     CDS             complement(25323..30626)
                     /locus_tag="ACL29Z_000766"
                     /EC_number="3.2.1.97"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001032503.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0033926 -
                     endo-alpha-N-acetylgalactosaminidase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SpGH101 family
                     endo-alpha-N-acetylgalactosaminidase"
                     /protein_id="HGR0069104.1"
                     /translation="MNKGLFEKRCKYSIRKFSLGVASVMIGAAFFGTSPVLADSVQSG
                     STANLPADLATALATAKENDGRDFEAPKVGEDQGSPEVTDGPKTEEELLALEKEKPAE
                     EKPKEDKPAAAKPETPKTVTPEWQTVANKEQQGTVTIREEKGVRYNQLSSTAQNDNAG
                     KPALFEKKGLTVDANGNATVDLTFKEDSEKGKSRFGVFLKFKDTNNNVFVGYDKDGWF
                     WEYKSPTTSTWYRGSRVAAPETGSTNRLSITLKSDGQLNASNNDVNLFDTVTLPAAVN
                     DHLKNEKKILLKAGSYDDERTVVSVKTDNQERVKTEDTPAQKETGPVVDDRKVTYDTI
                     QSKVLKAVIDQAFPRVKEYTLNGHTLPGQVQQFNQVFINNHRITPEVTYKKINETTAE
                     YLMKLRDDAHLINAEMTVRLQVVDNQLHFDVTKIVNHNQVTPGQKIDDERKLLSSISF
                     LGNALVSVSSDQTGAKFDGATMSNNTHVSGDDHIDVTNPMKDLAKGYMYGFVSTDKLA
                     AGVWSNSQNSYGGGSNDWTRLTAYKETVGNANYVGIHSSEWQWEKAYKGIVFPEYTKE
                     LPSAKVVITEDANADKKVDWQDGAIAYRSIMNNPQGWEKVKDITAYRIAMNFGSQAQN
                     PFLMTLDGIKKINLHTDGLGQGVLLKGYGSEGHDSGHLNYADIGKRIGGVEDFKTLIE
                     KAKKYGAHLGIHVNASETYPESKYFNEKILRKNPDGSYSYGWNWLDQGINIDAAYDLA
                     HGRLARWEDLKKKLGDGLDFIYVDVWGNGQSGDNGAWATHVLAKEINKQGWRFAIEWG
                     HGGEYDSTFHHWAADLTYGGYTNKGINSAITRFIRNHQKDAWVGDYRSYGGAANYPLL
                     GGYSMKDFEGWQGRSDYNGYVTNLFAHDVMTKYFQHFTVSKWENGTPVTMTDNGSTYK
                     WTPEMRVELVDADNNKVVVTRKSNDVNSPQYRERTVTLNGRVIQDGSAYLTPWNWDAN
                     GKKLSTEKEKMYYFNTQAGATTWTLPSDWAKSKVYLYKLTDQGKTEEQELTVKDGKIT
                     LDLLANQPYVLYRSKQTNPEMSWSEGMHIYDQGFNSGTLKHWTISGDASKAEIVKSQG
                     ANDMLRIQGNKEKVSLTQKLTGLKPNTKYAVYVGVDNRSNAKASITVNTGEKEVTTYT
                     NKSLAFNYVKAYAHNTRRDNATVNDTSYFQNMYAFFTTGSDVSNVTLTLSREAGDQAT
                     YFDEIRTFENNSSMYGDKHDTGKGTFKQDFENVAQGIFPFVVGGVEGVEDNRTHLSEK
                     HYPYTQRGWNGKKVDDVIEGNWSLKTNGLVSRRNLVYQTIPQNFRFEAGKTYRVTFEY
                     EAGSDNTYAFVVGKGEFQSGRRGTQASNLEMHELPNTWTDSKKAKKATFLVTGAETGD
                     TWVGIYSTGNASNTRGDSGGNANFRGYNDFMMDNLQIEEITLTGKMLTENALKNYLPT
                     VAMTNYTKESMDALKEAVFNLSQADDDISVEEARAEIAKIEALKNALVQKKTALVADD
                     FASLTAPAQAQEGLANAFDGNLSSLWHTSWGGGDVGKPATMVLKEATEITGLRYVPRG
                     SGSNGNLRDVKLVVTDESGKEHTFTATDWPDNNKPKDIDFGKTIKAKKIVLTGTKTYG
                     DGGDKYQSAAELIFTRPQVAETPLDLSGYEAALAKAQKLTDKDNQEEVASVQASMKYA
                     TNNHLLTERMVEYFADYLNQLKDSATKPDAPTVEKPEFKLRSLASDQGKTPDYKQEIA
                     RPETPEQILPATGESQSDTALFLASVSLALSALFVVKTKKD"
     gene            complement(30927..32909)
                     /locus_tag="ACL29Z_000767"
     CDS             complement(30927..32909)
                     /locus_tag="ACL29Z_000767"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptide ABC transporter substrate-binding
                     protein"
                     /protein_id="HGR0069105.1"
                     /translation="MKSSKLFALAGVTLLAATTLAACSGSGSSTKGEKTFSYIYETDP
                     DNLNYLTTAKAATANITSNVVDGLLENDRYGNFVPSMAEDWSVSKDGLTYTYTIRKDA
                     KWYTSEGEEYAAVKAQDFVTGLKYAADKKSDALYLVQESIKGLDAYVKGEINDFSQVE
                     IKALDEQTVQYTLNKPESFWNSKTTMGVLAPVNEEFLNSKGDDFAKATDPSSLLYNGP
                     YLLKSIVTKSSVEFAKNPNYWDKDNVHIDKVKLSFWDGQDTSKPAENFKDGSLTAARL
                     YPTSASFAELEKSMKDNIVYTQQDSITYLVGTNIDRQSYKYTSKTSDEQKASTKKALL
                     NKDFRQAIAFGFDRTAYASQLNGQTGASKILRNIFVPPTFVQADGKNFGDMVKEKLVT
                     YGDEWKDVNLADSQDGLYNPEKAKAEFAKAKSALQAEGVTFPIHLDMPVDQTATTKVQ
                     RVQSMKQSLEATLGADNVVIDIQQLQKDEVNNITYFAENAAGEDWDLSDNVGWGPDFA
                     DPSTYLDIIKPSVGESTKTYLGFDSGEDNVAAKKVGLYDYEKLVTEAGDETTDVAKRY
                     DKYAAAQAWLTDSALIIPTTSRTGRPILSKMVPFTIPFALSGNKGTSEPVLYKYLELQ
                     DKAVTVDEYQKAQEKWMKEKEESNKKAQEDLAKHVK"
     gene            complement(33230..34333)
                     /gene="glf"
                     /locus_tag="ACL29Z_000768"
     CDS             complement(33230..34333)
                     /gene="glf"
                     /locus_tag="ACL29Z_000768"
                     /EC_number="5.4.99.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000272499.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008767 - UDP-galactopyranose mutase
                     activity [Evidence IEA];
                     GO_process: GO:0009273 - peptidoglycan-based cell wall
                     biogenesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopyranose mutase"
                     /protein_id="HGR0069106.1"
                     /translation="MYDYLIVGAGLFGAVFAHESALKGKKVKVIEKRNHIAGNIYTRE
                     EEGIQVHQYGAHIFHTSDKEIWDYVNQFAEFNRYTNSPVANYKGEIYNLPFNMNTFNK
                     LWGVVTPAEAQAKIDEQRAILNGKTPENLEEQAISLVGTDIYEKLIKDYTEKQWGKPT
                     TELPAFIIRRLPVRLTYDNNYFNDTYQGIPIGGYTQIVEKMLDHENIDVETNVDFFVN
                     KEQYLKDFPKIVFTGMIDEFFDYKLGELEYRSLRFENETLDMENYQGNAVVNYTDAET
                     PYTRIIEHKHFEFGSQAKTIITKEHSKTWEKGDEPYYPVNNDRNNHLYKSYKKFADEQ
                     GNVIFGGRLGHYRYYDMHQVIGAALQCVRNELD"
     gene            complement(34347..35345)
                     /locus_tag="ACL29Z_000769"
     CDS             complement(34347..35345)
                     /locus_tag="ACL29Z_000769"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002884995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016747 - acyltransferase activity,
                     transferring groups other than amino-acyl groups [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acyltransferase family protein"
                     /protein_id="HGR0069107.1"
                     /translation="MKKIRNINLDLLKVLACVGVVLLHTTMAGFKETDSWNLLAYLYY
                     LSTYSIPLFFMVNGYLLLGKREITYHYILQKVKWILITVSSWTFIVWIFKRDFTTNPI
                     KKIVGSLIQRDYFPQFWFFGALILIYLCLPILRKFLNSKRSYLYSLSLLLIIGLIFEL
                     SNILLQMPIQTYVVQTFRLWTGFFYYILGGFIAQFTIEEIESRFKNWMKIVSILLLLI
                     SPIILFFIAKTIYHNLFAEYFYDTLFVKVSTLGIFLTILTLTLNENRRESIVSLSNQT
                     MGVFIIHTYIIKVWEKLFGFNFVGAYLLFALFTLSVSFIITGMLMKIPYFNRIVKL"
     gene            complement(35347..36762)
                     /locus_tag="ACL29Z_000770"
     CDS             complement(35347..36762)
                     /locus_tag="ACL29Z_000770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003009066.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0140327 - flippase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="flippase"
                     /protein_id="HGR0069108.1"
                     /translation="MKILKNYAYNLSYQLLVIILPIITTPYVTRVFSSYALGTYGYFN
                     SIVTYFILLATLGVANYGTKVISGNRKEIEKNFWGIYSLQLCAAVLSLSLYVVLCLTL
                     SLMQNPVAYILGLSVVSKGLDISWLFQGLEDFRKITVRNITVKLIGVISIFLFVKSES
                     DLYLYIFLLTIFELLGQLSMWLPAREFIGRDHFDIAYVRHHLKPVILLFLPQVAISMY
                     ITLDRTMLGALASTKDVGIYDQALKLVNILMTLVTSLGSVMLPRVAHLLSKGEQKAVN
                     KMHEISFLIYNLVIFPVIVVILIVNDDFVQFFLGQDFQDARYAIAIMIFRMFFIGWTN
                     IMGIQMLIPHNQNKEFMISTTAPAIISVGLNLLFLPKFGYIGAAIVSVLTEAFVWAIQ
                     LFYTRRYLKGVPIIGSMAKIILASTIMYGLLLSSKTVIHFSPTLNVLAFAALGGIIYL
                     FAILSLKVVDVKELKQIIRKN"
BASE COUNT        10892 a         8142 c         6470 g        11304 t
ORIGIN      
        1 aattctaatc ttaggtatat gattaaattg attgatcgtt acggaataga gttcgtcaaa
       61 aaagggaaaa atcgttacta ttctcctgat ttaaaacaag aaatgagtaa taaagtctga
      121 catgaaggct ggactaaaga tagagtttct cttgaatacg gtctcccaag tcgtacgata
      181 cttcttaact ggctagcaca atacagaaaa acgggtatac tattgttgag aaaccaagag
      241 ggagagtacc taaaatggga cgtaagccaa aaacgagacc tgaagagagg acagaattag
      301 aacgtcttca agcagaaaat gaatacctga gagcggagaa tgccatccta aaaaagttaa
      361 gagaactccg attgaaggag gaaaaagaga aagacagaaa ttgttcaaga attaatgact
      421 gagttttcgt tagatcttct tctaaaagcc attaaactag ctcgttggac ctactactat
      481 cacttgaaac agctagacaa aacagataag gaccaagagc ttaaagctga aattcaatcc
      541 atttttatcg aacacaaggg aaattatgct tatcgctgta ttcatttaga actaagaaat
      601 cgtgcttatc tggtaaatca taaaagagtt caaggcttga tgaaagtact caatttacaa
      661 gctaaaatgc gacagaaacg aaaatattct tctcataaag gagacgttgg taagaaagca
      721 gagaatctca ttcaaggcca atttgaaggc tctaaaacaa tggaaaagtg ctacacagat
      781 gtgacagaat ttgccattcc agcaagtact caaaagcttt acttatcacc agttttagat
      841 ggctttaaca gtgaaattat cgcctataat ctttcaactt cacccaactt agaacaagta
      901 caaacaatgt tggaacaggc attcaaagag aagcactatg agaatacgat tctccatagt
      961 gaccaaggct ggcaatacca acacgattct tatcatcggt tcctagagag taagggaatt
     1021 caagcatcta tgtcacgcaa gggaaacagc ccagacaacg gtatgatgga gtccttcttt
     1081 gggattctga aatcggagat gttttatggt tatgagaagt catttcagtc gcttaagcaa
     1141 ttggaacaag ctattgtaga ctatattgat tactacaaca ataagaaaat taagataaaa
     1201 ctaaaaggac ttagtcctgt gcaatacaga actaaatcct tcggataaat taattgtcta
     1261 actttttggg ggcagtacat aagaaccttg gtaatatgcg ttttttgatt gtgaagactt
     1321 ttatccacct attatacaaa gtcaagtatc catcacagtt tacaattagc cttcattact
     1381 taacccattc accattatag tttaagtagt aaccacctac tgtggtatta acagctaaag
     1441 cacctgaatc ataggcatag taccagttac cattgacttg gaaccagcct gttttcatat
     1501 ctccattact tgcatttaga tagtaccaag tcgaaccttc ttgataccag ccagttgcca
     1561 ttgctcctga tgaacggaga tagtaccact tgttcccaag gtattgccag ccagttctca
     1621 tatcaccatt ttcagtatct aaatagtacc aagttgagcc ttccttatac cagccagttg
     1681 ccatagctcc tgacgaatgg aggtagtacc acttattacc tagatattgc caacctgttt
     1741 gcataatgcc agttactgga tctagatagt accatggagc tgcttttagc ttctcttcat
     1801 cataggtaag agggtaatcc ttaacccaac cacgtgctag ctctccaacc gtcaatctgt
     1861 tgatgcgcga atcaaagcca ccatccttct gtaaataata ccaatgaccc tcttcataaa
     1921 tccaaccagt ttttaaagta tgataactac gctgatcttc aaaataatag actcgtttct
     1981 ctgcttggct atcatattct tccccatgat gtttgttggt attcgtagca gtttttgctt
     2041 ctaaaacttg cttgccaaca aattcttgta atacaccatc ttgaccaaaa taaaaccaat
     2101 ctggtctaag agcaatctct attcttggag aaggaccaat cgtaaccccc ttgtgtggag
     2161 caggtatata ttgccagccg acaaccatct ctccggataa aggatcaaaa taatagtact
     2221 tcccatctat cactctccag taggtttctt ttagatcccc ctttttgtag taggttctac
     2281 cattttcttg gacaaactgc catccttcag aatcatctgc aaatactgta ctggtcccta
     2341 gcaaaccgaa gaaaaatgtg gctagtgcga cttgcatcat ttttttcaaa agcttcaatt
     2401 tatatatcct ccaacatcaa atccactccc cagatgaagc gaagttataa actttaccat
     2461 cgatagtttg gctacctgta accattgctc catttgaatt gagataatac cagtttccat
     2521 ttactttttg ccaatctgta agcatcttac cggaactgtc taaataatac caagtatcat
     2581 ttatctcctg ccaacccgtt tgtttatcat gttgtctata atagtaccaa ctaccattta
     2641 ttttcttcca tccttcaaga gagtaacctt taagaaccga ataaataaat gacaaatttc
     2701 gttcatttaa tttaactgca ctgttaattt gattagctcc atctcctaaa gtatgcactc
     2761 ctactacgcg gtgactagca tcataaactg cagatccact agacctctct aaagtatcaa
     2821 cttggtaatc caagaacatg ccatcatcac ttaaaacttg ttttttatct gtatacattt
     2881 gataaatttt aaaattatat gatggatagc ctgtgatagt cacagttatt cctgtcaaat
     2941 ttttttgact agtaggaaga cccaaagtcc ctaattttgc accaatgggc ttttctagaa
     3001 ttaataaagc caagtcatat tcccttgcat ccttagaatt taaatttcta aattccttca
     3061 aataacgaac ttcctttact ttgatctttc caaatggttc ttgacttgga ctaacagcca
     3121 gaagaacata aatatcatcc gcttctttcc catagtcatg tctgtagtag ttgtgagccg
     3181 ctgtaattaa cacattatct ttaataaaat tcgcacttcc cctcccttct acattcattc
     3241 catcggctac tccataatac ttagataaaa ccatagctga agtcgaatac ggatactgtg
     3301 aagtattatc aattttaatc aaatcatcat taccgataat acttctgatt gcttttggta
     3361 gtatgaacca tacgttggtg aaatctcaga taatgaagaa tcattagacc ctggaccttt
     3421 ttctagtgtc tcacttacct catattcttc acctgtacta gaaataacac tcaaagcaga
     3481 tactgtcgat aactggctag ccaataaagt actcgcaata attgaaatac ccaatttttt
     3541 ataaacagtt ttcttcatta ttgtatcctc ctaatgtaat tatagcgtac tattctaaat
     3601 ttcttaatct actatagaat caagaaatct accaccttct ttaaataccc tccattatca
     3661 cataaacagg taaacttttc aattaatgac tgcgcttttc aatcacgcta gaggtacttg
     3721 cttgcttctt tgatactaag ttcagccatt ctttccttgt ttttctcaat aaagcatgtt
     3781 acccaagtgg gattcgtttt ggagtagtct cgcagagtcc agccaatggc tttattgata
     3841 aaaaattctg tttggttcaa gttatgaagt agaatctttt ccattaattg agtattggtc
     3901 ttctcttttc ttaacaactg gtggtcaata gcgacacgtc tcagccagat attatctgat
     3961 aggctccatt ttatactcaa tgaaaatcaa agagcaaact aggaagctag ccgcagattg
     4021 ctcaaaacac tgttttgagg ttgcagatag agctgacgtg gtttgaagag attttcgaag
     4081 agtattaaga ttatttcttc tagttcagag tgttcataca ccaaactccc tactactcga
     4141 tctaggatat ctaccgtgtc ccaccaggat tttgtcacga ctaactgctc tagcttaggc
     4201 aaatcggttt cctttagata agactgcatt gctttcaaat agttagcagc cacatattgg
     4261 tattctctag gatccttttc ccagcaagtg tctgcaaaat cccaatcgat aatctttgtt
     4321 tttttcgctt ctggaaaata tttttataga gtttatttct ttcaggcacc gcaataccta
     4381 gaaaagaaaa ttgatggcgc atataggctt ccatggacct tgctttttta gagtcttttg
     4441 ctgcttctag ctcctcaagt aaatctgcta aactcatcta aaactcatct tgccccacca
     4501 aatggtgctg aaaggcatag acagccgcct gggtacgatc gctgacttca agtttggcaa
     4561 gaatgttgga cacgtgggtc ttgaccgtct tgagagagat aaagaggtca tctgcgatgc
     4621 gctgattttc gtagcccttg gcgatgagtt ggagaacatc tcgctcacgc gcagtcaatt
     4681 cttcatgaag ttccatatga ttgcggtggt attcaacctt cttgctaacc tcttgctcaa
     4741 tggccagctc gccagcagct accttactga cggcatgaag caattcatct gcactagaag
     4801 tcttgagcat atagcctttg gcaccagcat ctaagactgg catgattttt tcattgtcca
     4861 aataagaggt cacaatcaaa atcttggctt caggccattc tttaaggatt gctaaggtcg
     4921 cgtcaatccc attcatctca ggcatgacaa tatccatgac aatgacatct ggacgcagtt
     4981 ccaaggccaa gtcaatccct tgagacccgt tggacgcctc acccacaact tctacatcgt
     5041 cttggaggtc aaagtagctt ttcaagccca atcggaccat ttcatggtca tctactagta
     5101 aaattttcat ctttactcct ttatcattcc ttatctaaca ggggaatacg gatatcaact
     5161 gccagccctt gcttgggagc tgttaataac tgaaccgtcc ctgccatatc ttcaacccgc
     5221 tccttgatat ttcgcagtcc ataactcaag tcgtctaagc tccctaaccg gaaaccaatc
     5281 ccattgtcca ccaccttcag ttgcaattca acatctgtct gatagaggta gacatctagg
     5341 caagatgcct gggcatggcg gagcgtattg ctaatcaact cttgcagtat acggaagata
     5401 tgctcctcga ttttcttagg caatttcgtc atattctgct tgagactaac cctaagatca
     5461 ctcttgtcct caagctcttt taagagaatc tgaatccctt ctatcaagct cttctgctcc
     5521 agttcaactg gtcgcaaatg caagagcaaa acccgcaaat ccttctgggc agtttctaaa
     5581 atagctgtga cactctgcaa ctggatctgc atcttttctc tatccaattt caaagcctgc
     5641 tgactgatac ccgataaaat catgtgggcc gcaaacaact cctgactgac tgtatcgtgc
     5701 aaatcccgag caattcgctt ccgttctttc tcgatgattt cctcttcctg agcaaggcta
     5761 tgattttcag ctttttgaag agcttctgtc aaaaggttaa gtttacctga taaggacttg
     5821 aaactggcat ccaaatctgg atctgcaacc tgaaccactt cttgccctgc caataaacgc
     5881 ttgagattag cctgcatttt tcttagagaa agctcttcga tccctcgcca aaacagggct
     5941 aagagacagg ttatggacat gctgaaaacc aacaataaaa agacaaactt ttctgttttt
     6001 tcgacatcgt gcaaaaagat agaccagtca aaatcaagta tttccagcaa gctgtgggag
     6061 aaaaaaaaga caaataggaa ggaggtgaga gcaataatga cataggcttg ttttttcatc
     6121 ctctaaccac ctccacatca ccaatcatag tggtcaagaa aatcttgaca ctcttgttac
     6181 tcttgagata gtcttttgtt tcttgatgat agtgttcatt gcggagggct cgcttgggct
     6241 ggttgaaaaa agtcaaatcc ccatagagac agttaacgct gagactgact tccacatcta
     6301 caggtacgat gattttggtc gttcctacca tctttctgag gataatgaca ttgtcatgat
     6361 tggttaagat gaccctctcc agatgaatag tgtccttgcc catgaagcga aagagattga
     6421 tatcatcgaa ttggcaagtc tggtagcttg aaaaatgatg aagatttcca aaccaacgat
     6481 ttttctcctt cttaaccgtc acgacctctt caaaaaccaa attggtctgc tctttttcct
     6541 ggttcatcat cgggtaaaga agaaagaggc tatagataac cgcaacaaaa atagctagaa
     6601 tcacaaaagg attgagcata acgatgaaaa agaagagaat ggttgccgct actaaaagaa
     6661 gattatttcc ctctttacca gtgtagtagc gaatcaaaag caaaaagagg aatagtatca
     6721 gcagaaaacg cgaaaaatgc tctgatacca tcaaaatcag agctcctgtc agaagacagg
     6781 cttcgataaa taaaaagatt ttaaattttc tcataggttc atcctctccc ttctatttta
     6841 tcacaattca aaaaagtcac ctcagtctga ggatggaaaa aaaggcgctg gttacgcctt
     6901 tttcatctga tcctttgctt cttttaattt tccataaaga agatagtcta ctttttgtag
     6961 atctgctatg gtggcacagt taagggaaca cataatcaag cgtagatctg ctttccagcc
     7021 ttggacaatg ccaatcactt cttcaactgt gtaggtttca accaattcca gaacggttcg
     7081 tgacaatccc acagccttag caccaaaaac caagcactta atcatatcca gcggattccg
     7141 aacccctcca ctaaccaaga gttcgacctt atctttccat tcttgggcat tgagaagggc
     7201 ctgcatggta gactgacccc attgattgag gtaatcacgc tggccactac gacggttttc
     7261 gatataggca aagctggtgc caccacgacc cgataggtcc actgtacgaa caccgaattc
     7321 ataggctctt tcgattgtct tggcatccat tccaaagccc acttccttga ggacaatagg
     7381 aacgggaatt tgcttgctat aatctgctaa atgcgattgc cagcttctaa acttcctttc
     7441 tccctcgggc atgagtaatt cctgcatgac attgacatgc acttgcaata gaacaggatt
     7501 catctcttct acagtctgaa gtcctaactc gacaggcttg tccaatccaa tattggttcc
     7561 aaggaggaga ttgggatgac tagacttgac agaaaaagaa tcatccgttg gatttttgag
     7621 ggctgcgcta taagaacccg ttacaaataa aataccacag gattccgcca cctgagccag
     7681 cttttgattg atttctcttc ccttattact tccaccagtc atggcattga tataaaaagg
     7741 aaagtcccac tttcgaccag caaactctgt cgaaagatcg atttcatcca gattgtaaag
     7801 aggcaaggaa gaatgaatca gctccacctc atcaaagcta ttataggaac ttttctgctc
     7861 aagggcatag aggatatgct cgtccttacg atttgtcgtc atgtcctatc ctttcttgat
     7921 ataagagctc aatccccaga tcggcccaac gattttttaa ggttttggtt gattgcgcat
     7981 caaaactcag ggcgatgcca cagtcaccac caccagcacc actactcttg gcaacggcct
     8041 gcaaatcttg actggcttct ttcaactgtc taagcaaagg cgtgtaaata tctgtactca
     8101 agccttctaa aagcttgctg gctactgcta cttgctcgat aatcttttct gatttcccct
     8161 gttccaaggc ttcgaccaaa gaaaccaccg tttcttttga ggaagttaaa aaattttgat
     8221 tgatattttg cttgatttgc tgaaccatgt gactcgatac agccacttcc ttggtccatc
     8281 ccactaagaa atcacattct aaagttggtt tcacttgtga gataaaaaat ccccaatcac
     8341 gctccagaac tgtcgccaag ttttcttctt ctaaccaagc agccgccttc tggcgatcaa
     8401 atgactggta gagaaccaaa tcctctgcca caatacaggc aaggtcgccc atggaaccat
     8461 tgtctcctcg cttgagcaag acagcgctag tcagcttgaa caagagctcc tgatcaacag
     8521 aaacatcata cagagccagt aaagccttga caaccaagac aacgacgctg ccactagaac
     8581 ctagaccaaa ctttttccct tctcgttcca ttttgccaca gatttctaga gaaaaaggtc
     8641 ttaaattctg accgcgaaca gcgaggaagt ctcccatcaa agcaatcgtt tcttgaatca
     8701 agctgtagtc aggattgggc cttaagtcca ctgcgaaatc aaacatatct gaatagatac
     8761 ggtagctgtc agaaaaagca atctcagccc tcatatagat gggaatatcc tttatcaaag
     8821 ctaaccgccc tggctctaaa atagcatatt cacctgccaa atagagtttt ccgcaagttt
     8881 taacagcaat catcttgact caaatccttt gtttttgaca caatcaagcg ataacgctga
     8941 ccgaaaattt ctgacaaatg ctccaagtct ttctcctgac agaagacctt aacattggga
     9001 ccagcatcca tggtaaagta gcaggcctct cctttctcac gaagctgacg aacaaaggcc
     9061 atagcctcat aagaggcatc cgtcagataa gaaaaggctg gactagcagt ctttgtcgta
     9121 gcatgcatag ccagggcatt tttctccgtt aattctccaa tcttggcaaa atcattttcc
     9181 ttgagataaa tcagcatatc ctgatagtcc ttctcagact gacgaaccca gtcgtcgaaa
     9241 gtcgtcgagg tttccacaca aagtttcatc ccgtcacggc tagagattgg ttttttcttg
     9301 tcctctagca ccaacataat catagctagt ttcaagtctg tctctacagg gtaaatttct
     9361 ccactatcct tatcccaggc tcctagtggt ccataaaaac tccgagaaga agagcctgag
     9421 gcaaatttgg cttcctgtgc caactgactt ctatccaatc caagtttgaa ataagcatta
     9481 caagccttga ccagggcgga caaaccacta gaacttgagg acaggcccgc tgccgtaggc
     9541 atattgtttt gagtatcgat acggacaaag ccctcaccag ctggacgata acggtcaata
     9601 atcttactca tcttggcatg ctcgacctca ttttgtagct gaccattgat gtaaaattcg
     9661 tcagctgtta cattggctgg taaaggcgac aaggtcgtct ctgtatacat attttccaaa
     9721 gttagagaaa tactgctagt agcaggcacc atctcttttt cttttttctt tccccaatat
     9781 ttgataatag caatatttgc gtaggaacgt actgttacag gctctctatc catgtctgaa
     9841 cagctccttt ctcttctaat ctttctgcta gttcttgtgc gtgtgtcaaa ttggttacca
     9901 aggctatgat acaacctcct agcccaccac cgctcatctt ggcacccaga gcaccatggc
     9961 taagagtcgt ttcaaccaaa aagtctgcct cagggctact gactccaatt tcttttaaat
    10021 gtaaatgcgc ttgactgagg atttgtccca gtccttcagc atctttttgt gaaatcgcaa
    10081 cttctgcttg ctgggttaat tctcccaagg catgcaaaaa cggtagggca tccttgccct
    10141 tattttgaac cacttggatg gcttcacgag tatgaccata aacacccgta tcggcaatca
    10201 ccaaataggc ggataaatcc atctcaagtt ctgtaaatcc tacgttcttg ataaagcgaa
    10261 taggttggtc actgagacag gtcttagcat ccaaaccact aggattcata tgggcaatca
    10321 tctcagctcg attgaccaag atttctagta catcatgagg cagatcagcc tgatagtagt
    10381 caaataccgc acgaatggcc gctatgctga tagccgctga cgaacccatc ccccgtttct
    10441 cagggatagc cgagtcaatc tcacaacgaa cgcaggcttc tgtgatatcc aaatactcca
    10501 gtgaggcata aaccgccatg gacaaggtat cctcctcata aaggcgccaa ggactctctg
    10561 cagaaactac cttacaggtc acctccacct ccaaaagagg cagggaaatg gcaggataac
    10621 cgtaaacgac cgcatgttcc cctattaaaa ttatcttact atgtgcctga ccgacaccaa
    10681 ctttttttgt cattttttcc ttttactaga cgaaaaaacg tcttattttt catacaagta
    10741 ttaattcttt cctatctatt ttattatatt ttcacaaaaa aagcgattgt ttccattcac
    10801 aatcgcttct ttcattattg aacccattcg ccattataat tgacaaaata gccatctacg
    10861 gtcgtattca ctgccaaggc acctgagcta taagcgtagt accatctgcc attgacctgg
    10921 aaccaacctg tcgtcataga acgacgaaag aaactccata ccattaagta aagaggaaag
    10981 tcgtgaggga gcatgcgcca ttgacaacct gttttagtga cgtacaaagt ctcattaaca
    11041 agtactcgtt tcggccattt ataggtgcgg tgtttggaga aatagggttc aatcttagcc
    11101 cattcttgat cgtttaaatc agtatcatat actttgcgtg tcataactct agtttaacat
    11161 tttttgtgaa tacaggttct aaataatcga ccacgaaaat ttcttaagtg gaaaacgcct
    11221 tatgaagtat gctacgggaa agttatgcac ttaatttgac aattcaagat gtaaaaatat
    11281 atactatagt agattgaaac tagaatagta cacctctact tctaaaatat tgttagaaat
    11341 cgatttgact gtcctgatcg atttatcctg ttattatctc attttgctat aatatttgac
    11401 aagttatcct aaaagtatta ttatgttgtt gtgttataga ttgattgaat ctaactaaag
    11461 gatcctattc aattactaga actatcacat actcaaggtc agctcacaga tgagcaacta
    11521 ttttggttac aatgtctact aaatttaagt caaacaaata atttagtcaa aattaaaaaa
    11581 atagaggaac ataaatatga ttacaaaaca gaatgtaata gtgttctaca atttttacta
    11641 gataaaactg taaattctga aggaaggatc acttcttcaa cagaatttgg aaatttcgta
    11701 agtaatttat cattccaaca cggaatagct ggactactgt ttcctctaaa taaattgtac
    11761 cccccagaac tggattctaa aatactctct atcatcaaga aggcagtgac aattagaacg
    11821 acacatacat atgaatatca atactcactg ctatttggtg atgcaggcta tctatggtta
    11881 ctcctacatt tattttctat cagtaaaaat caatactatc tacaattagc aaacgtcacc
    11941 gctaaaaaat taatagagaa ttatgatact ctagaggaaa tagactttgc attgggaaaa
    12001 tctggtgtcc tattatcatt aataaaatac tatcaattta ccaatgacaa tactcttaaa
    12061 attttcatcc acaatagtat aggggaaatt tatcattatt tcctacaaag agatacagcc
    12121 aaagaaagca ttttagacta tagctttgct catggatatt gtggaattgc atatgcttta
    12181 tttgcctatt ctaaagtctt agaaccttct atgttctata atgatctcca tacattccat
    12241 actgaattaa aaaaattatt agaaaaagtt acttctaata ctgaaaattt aggaaattta
    12301 caactttctt ggtgcaaagg aatttccgga ataatcttat atctttgtat gtacgattgt
    12361 gacggaaaca aagatattat tagtaaatat caagaatttg tttttaacca tcatctaaaa
    12421 atgatgacag gatattgcca cggaataact agcttactac aaaccactgt ctacaatcaa
    12481 aacaaattac tgatgaaaaa aatccaacag gtaattttag catgttctga acgagatgat
    12541 cacggtttac tgatgtttca aggagatagt ggtaaagcag atttgtttga cttcggaata
    12601 ggaagcatgg ggtatattgg tgtctattaa ataataaatt cccattcgat gtgcagacat
    12661 aaggagaaaa gtatgaaatt attttggaca aacaacatat atagacagtt gctgctaaac
    12721 agctgttttt catcattcgg cgacagtatt ttctacctcg ccattatcaa ttatgtggct
    12781 cagtacaatt tcgctccgct agcgatttta ctgatttcca tttcagagat ggttccccta
    12841 ctatcgcaac tctttctcgg gattctagga gattttcaag aaaatagagt caaacacgca
    12901 ctctggattg ccaaaatcaa aatcctgctc tacgctattt tgacagtatt tctcgtcttg
    12961 tcgccctttt cattagtttc agtcattatg attgtcatca tcaacctcat ctctgacacc
    13021 ttgagctacc tgtctgccta catgatgaac gccctctaca tcagtgtaat taaggacgac
    13081 ctgcatgatg ccatggggtt caggcagtct ctgatgaggg ttgtccgtat tgtcgccaat
    13141 ctggctggcg cattccttat caatgttata agtattcaaa ctatttccct tatcaacact
    13201 ctgacttttg tcattgcctt tttgggcctg tatgttattc gacatacctt gtatgaggtt
    13261 gaaaaaagaa ttgaaatgtc acatacagca ctgagtttta agaaatattt tcaacatctt
    13321 aaacagtcgc tggctgtgct cctgaggtta aaagataccg tcatactact gtttctgacg
    13381 accagtatga ttgccatctt ggatgtgtcc cctcggctga ttgccctccg cttcatccaa
    13441 cagacactag cacaactgag cattgggcaa ctcctcgccc tgctctccat catcatgtct
    13501 tgtggagcta tccttggcaa tatgaccagc agtaatctat ttaaaaatat ccgtttcacg
    13561 cacctcttgg ttttctgtga gatttcccta ttgactctaa taactagtat cctttgtcaa
    13621 gcctatatcg taattttcat gaccagtttc atcagttcta cgattatcgg cattctcagc
    13681 cctcgcctac aagcagctgt ctttgcccat atccccagtg acaagatggg gacggtgggc
    13741 tctgctctga gcacagtgga cattctcgcc ccgtccctgc tctccctatt agccctatcc
    13801 atagcatcgg gcgtttcggt gcagttagca ttgatatttt tgtatcttat tttaattgct
    13861 cttatctttt gtcaatggtt agtcaagttc aacactcata actaacgaaa aagcatgtgt
    13921 agatttcaca tgcttttaat ctccccaatc gtcaggtcaa gtacaacaaa gtcacttctt
    13981 tgattaagcg agtgttctaa tataattata agcgccctgt cattaccgaa cccattcgcc
    14041 attatagttg acagaatagc catctacggt cgtattcact gccaaggcac ctgagctata
    14101 agcgtagtac catctgccat tgacctggaa ccaacctgtc ttcatgtctc cattacctgc
    14161 atttaggtaa taccaagttg agtcatcttt cacccagcca gtcaccatgg cgcctgacga
    14221 acggagatag taccatttgt tcccaaggtt ttgccatcct gttttcatat cgccatttgg
    14281 ctggtctaaa taataccaag tggtaccttc ctgataccag ccagtggcca ttgctcctga
    14341 ggaacggagg tagtaccact tattacctag atattgccaa cctgtttgca taataccagt
    14401 tgttggatct aaatagtacc aagtcgaatc atcgtttatc caccccgcac gtctttcacc
    14461 accaaggtag ttttctccat taatttccgt cttagctaga taataccagt tagactgatc
    14521 ataaagccaa cctgtctcta aagaatgatt ttgattaaag taatagttcg tataataacg
    14581 tttctcttct ttatcttctg aatcttcacg tttttccccg tactttcttc caacactgtc
    14641 tttagtttta atctctaatg ttttccaacc aacaaactct tgtagcactc catttttatc
    14701 gaagtagtac cactctgact ttggaaaacc ttctaatctg ataccatttg ggtaaggacc
    14761 aattgtacta cctttagatg gaaacgggat atattgccag ccgacaacca tctctccaga
    14821 tagagaatca aaataatagt acttaccatc aatcactcgc cagtaggttt ctttgaggtc
    14881 cccctttttg taataggttc taccgttttc ttggacaaac tgccatactt cagagttatc
    14941 tgcaaatact gtattcgtag ctagcaaacc aaagaaaatt actgttagtc cagcttgcat
    15001 agtttttttc aaaagcttca ttttatatat cctccaacat taaatccact caccagatga
    15061 agcgaagtta taaactttac catcgatagt ttgactacct gtaaccattg ctccagagga
    15121 attgagataa taccattttc catttacttt tgtccaacct attttcatat caccattttc
    15181 agcatctaaa tagtaccaag ttgaaccatc ttgataccag ccagttacca tagctcctga
    15241 tgaacggagg tagtaccact tgttaccaag gtattgccat cctgttttca tatcaccatt
    15301 tttattatct aagtaatacc atttgcctcg tacatatttc caacctgttg ccatagaacc
    15361 agaggagcca aaataatacc attttccgtt tactttttgc caatctgtaa gcatcttacc
    15421 tgaagcatct aggtagtacc atggagcagg tttgcttcta tcaatgtcaa tagtaacatg
    15481 aaaatcttga gtccaaccct tagcaacttc accaattggt agtggattgt aagaatcatc
    15541 gccaaaattt cctagcttat ttaaataata ccaattgccg tcttcataaa tccagcctgt
    15601 ctttacagca taattattat caaaataata agttttcttt tcagcagata gaggatattg
    15661 ttcaccgtat acttttcctg tattttcaga cgtttttgcc tctagtactt gtttatctgt
    15721 ttgttctagc aaagcaccat cttgtccaaa atagtaccac ttctcctgaa ggccaatttc
    15781 gaagactgga cgattatcaa ataaatcatc acgataacct gttccatgaa tttctaagta
    15841 ttgccaaccg acaaccatct ctccaatatc accaaaatag taagttttac cgtctatttt
    15901 atgccaatag attgctttat gatcatcttt tacataatat tttctattat ccttatcaac
    15961 aaatcggcca cccatggtat ctgcaaatac tgtacttgtc gctagcaaac caaagaaaaa
    16021 gactgctaat gcgattggca tcattttttt caaaagcttc attttatata tcctcctaaa
    16081 acgattgtag taaaaactag attgtatgtc aatatataaa aactcctcaa aaaagcagtt
    16141 acacaactgc aactgctttt ctattcttgc atggtgtaac caacaccacg cacggtttta
    16201 atgtagcttt tttggccttt aacatcaagc ttgctccgta gatagcggat atagacatct
    16261 acgatatttg tctcggtcgc actttcatac ttccaaacac tttccaacaa ttgctcacga
    16321 gtcaatactt tcttacttcc cataagtgtc gccaaaaggt catactcacg gcgggtcaga
    16381 gcaatcatct cttcaccacg ataaaccgtg tgatgttcaa catctatcct aagattgcgg
    16441 taggtccttg gaactttcat cagactgcag tgttgatcaa tgaagtcccg acctcggaag
    16501 atcgccgaaa tacgcgctac cagattttcg ataaagactg gcttatagat gtatgaaact
    16561 gcaaaacgct gaacaacttc cagctcttct tgcaagtctt cccaatgatc taaaatcatg
    16621 atgactgagg caggtttagt tcgactcaat ttttctgcaa aatcctgagc catcatatct
    16681 cccagattaa cgttcaataa aatcaaatca tagtctgtct gaagagccat ggaaagggct
    16741 ttttgcccct cctctaccag atcaacccga tactgctctt tctggagttc caaacttaaa
    16801 aaatgagcta gatttcgttc tttctcaagt aataaaatcc gtttccccat ggctgaccta
    16861 cttatttttc gtcataccaa gagtagtgga aggttccttc tttgtcttta cgttggtaag
    16921 tgtgagcacc aaagtagtca cgttgtgctt ggatcaagtt agccggaagg tcagctgaac
    16981 ggtagctatc aaagtaagta atagctgctg agaaagttgg cactggcaca ccagcttgaa
    17041 ccgcaagagc tacgatatca cgcactgctt gttgatactt agcagtaaca tccaagaagt
    17101 actcgtccaa aagaaggttg gcaagatctg catcgcggtt gtaagcatct gtaatctttt
    17161 gcaagaaacg agaacggatg atacagccat cacgccagat agatgcgata tctgcaaatg
    17221 gcaagttcca gttgttttct ttagaggcta cacgcaattg agcaaatcct tgtgcgtatg
    17281 aaatgatttt tgagaagtaa agggcttgac ggattttttc aatcaattca gccttgtctc
    17341 cttcaaagtt gaaggcagct ggttttggaa gcaccttgct agcatgtaca cgttcttctt
    17401 tgtaagttga aatgtagcgt gcaaacactg actcagtaat cagtgacaat ggtacaccaa
    17461 ggtcaagaga tgattggctc gtccatttac cagttccctt gttacctgca gcatcaagga
    17521 tgtagtctac gattggtcca tcttggtctt catcgtcttt acggctcaag atatcagctg
    17581 tgatttcgat caagtagcta tccaattcac ccttgttcca ctcagtaaag atttcagcca
    17641 tatcctctgc agaaaggcct agcaagtgtt gcatcaagtc atagctttct gcgatcaatt
    17701 gcatatcacc gtactcgata ccgttgtgaa ccattttcac atagtgacca gctccatcag
    17761 gaccgatata agtcacacat ggtttgccat cttctggtgc tttagctgag atttcttcaa
    17821 gaacatccga aaccaattcg taggcctctt tttgtccacc aggcatgata gaaggacctt
    17881 caagggcacc tttttcacca ccagaaactc cagtaccgat aaagttgata cctgagtttg
    17941 ccaattcttc attacgacgg atagtatctt tgtagaaagt gtttcctccg tcaatcaaga
    18001 tatcaccctt gtcaaggtgt ggaagaaggg cttggatagt agcatctgta ccaggtccag
    18061 cttgaaccat cagcatgata cgacgaggtt tttcgattga gtttacaaaa ctttcaacgt
    18121 catagcttgg tacaaagttc ttttcaggat ggcaagcaat cacatcttcc gttttttctt
    18181 tactacggtt gtagatagca actgtgtaac cacgagattc aatattaagg gcaaggttac
    18241 gacccattac ggccatacct acaacaccaa agttagcttt tgtcatttga cactcctctt
    18301 gtttcatttg ttttatttta tcatttttac ttttgaaaag aaagaatttt gtaacgactg
    18361 cttagtagtc caagtcatcc gcatgaccag cgccatttcc gacaaagtag cctgtcttac
    18421 agttaagggt aaagagatag gttccatctg gcttatagag gttgtaataa ccattgccgt
    18481 taacgatatt gacacgttca aggatatatt ggtctccagt gatatagcca cgtgaacgtg
    18541 aagtcgctag aatttgttcc aagacaccat ccgcaaaatc ccaggcagag ttattactat
    18601 catcaatagc agactgatta taggcaacac gactggcact tctttgaaca gcaacccctg
    18661 cactcgagag acccatattg acttcactgc gactacttct agtctcattt gaactacttg
    18721 gttttggctc acttgtcgta tttgagcttg cttgactaga gcttgagctg ctagtttgac
    18781 ttgaacttga gctagaagta cttgtttgct ggctcttacc aagactgata gccttatcta
    18841 gcactttatc aagctccgta ttcccagttt taatatctgt aaatttagca tccgatttag
    18901 ctttggcatt ggtatccaac acaccatcca caatagctga tttttcaaat tgtgcattga
    18961 catcttgaat agccttgatt tgcgttgcta gactatcata tttagatttg gcaagcgtat
    19021 gttcacgact accttccagc ttatcaagca aggttttgag ttgactcagt ttatcaaact
    19081 ggctattttt caaagccgtt ttattgctat ctgtgtaaaa ggcgtcataa agtgtattaa
    19141 aatcatccac atctgattga ttggctgtag ttgattgaga agtttcaatt tccttggtcg
    19201 agcgattcac ttgacggtag acataataag cactgacaca aataattact gatacaagcg
    19261 ccaaaacggt caaaataaag ccttttttac ttttcttttc tgagtcctct tgatccagac
    19321 gagaaaggtt ttgctcctct tccacttctt cagtcatttc tgttggattt tcatcatcta
    19381 gcaatagagg atccaagcct tgctcctcat cgtccagagg caagggtagt aagatgtctt
    19441 cagaagatgg aacttcctcc gaagaagctt ctgacttctc tacagcctca cgcatctctt
    19501 gaattaaatc atccagactc tgagtttcaa cgaactcctc ttttttgtat tgacgagtcg
    19561 caaacttatc cgcctcaatt tcatctctgt gttgcttaac atacttgtcc aaaatggaat
    19621 cctcaggcaa gactcctgct tccacttctt catttttacg aatagcttga ccaactgtta
    19681 gctcttttgc ttcatcaaaa tcaaattgcg gttcttgacc ttctttttta tgacgatttc
    19741 gtcttttttt actcatgagt atccctttct attttacctc ttgccgtttg acacgctgac
    19801 caaaatattg atatagatcc actttcaagg ttccgttgta taacttacgc ttcttatctg
    19861 cttggctacc atacttgctt tcaaaagctt catcactagt caggataaat ttgctccaag
    19921 ttttcagcgg tgcaaatact tgccccatct cagcatagag cttggtcacc cctgcatcat
    19981 ctgacaaacg ttcaccataa ggcggattgg aaatgattac tccattgatt ttatcggaac
    20041 gtaaatcctg cacgcgcatc tgcttaaaag taatgtctcc tgcaacacca gctgcctgag
    20101 cattggcctt agcaatttcc accatgcgag catcaatatc acagcccatg atatccagct
    20161 caagctcacg gtctactttt ttagccgctt ctgtgcgcac ttcttgaatc aagcgatcgc
    20221 tgatccagtt ccattcctca aatgcaaaag agcgacgaag acctggcgcc atctttctag
    20281 caatcataac tgcctcaata cagaaagtcc ccgaaccaca ggtcggatca atcaaagtct
    20341 tgtctggata ccaattagaa agttgtaaaa tggctgctgc catattttcc ttgataggag
    20401 cgccaccttt ttcggtacga taaccacgtt taaagaggct agacccggtc gtatcaatca
    20461 tgacagttgc cacatctttg agaatagaga cctcaatctt aaactctggg ccattctcca
    20521 tcagaggaac cccttctggg cgagcatagt gtttctgcaa tttcttgaca acagctttct
    20581 tagaaatagc ctgaacactg ggctcattgt gaagtttgga cttaacacat ttagcttttg
    20641 aaatcgggaa ccgagctcca agtggtaaat aattttccca atccaaagcg aaaactccct
    20701 gaaatagctc ttcaaaagtc ttagctggga acgttcctac gataattttg atacgatctg
    20761 ctgcccgaag ccaaaggttg gtttcgataa tagctctcac gtctccttga aaacgaacac
    20821 gtccattttc aacctgacaa tcgtagccca actctcgcac ttcacgacca acgacagcct
    20881 caagccctgc tgccacagtt gcaattaaat taaattcttt tttcatgtta cagtcttgca
    20941 agacctttct atatgtccac tttaaaaaat gaggttgaga aaatttctca gccccaacct
    21001 atatgcaatt ttctataagc catgttttgt tccagaagtg actaggacca cttccttcga
    21061 taatcatctg tctaccacta acagctctag ctgatagcag tcagaatact acgttcgttt
    21121 ccgcgtactc catgccccga ccaaaatttg ggttgctagc ttgaggggtt taccgcgttc
    21181 cactctctct gtttccagaa agactccgtc actgtggcac tttcaagcct actctggcct
    21241 atccaaggac ttagccattt caactgccgt aacgattcct cgtccctagg cttatggttt
    21301 cgcctagcac aaacactaca ggcatcacag cctgtgctag catggacttt cctcatgaga
    21361 agcaattctc ctcacgcgat tatccaaaaa ttgcacatct caaataacta cttaaaaatc
    21421 tgagttatct aaaatttgtt taccaaaaac ttctttttcc aatctattca ggcgtttcaa
    21481 aatatcaaaa ttcgtcatag aacttgtaat tgccgcttca aggggttctg cttgaactgg
    21541 tgaaggtttc ggtttacgag ttaattcttc cttcaaatcc gcaatttcct gacgaagtga
    21601 cttgaccaag gcagcatagg tttcatagtc cttgatgaca tcgtccaaaa actcgtcaac
    21661 ttctacttta ttatagccac ggacttcacg tccaaactct tgttcaaaaa tatctttcgc
    21721 tgaaaaaata atacttgcca tgtctctctc cattctcgct tgctagtatt attatataaa
    21781 aaaaggcaaa caaaaatcaa ggtcaaagct tcaattttcg gaaaaatttt cagcaagttc
    21841 atttaattga tcaaatgtta atctctttat aaaatagtcc tcttgatttt tcatcttttg
    21901 gtaaaaataa gctagttttg tttcattttc ttcatcataa aaaagataag aactagtcgt
    21961 gttttccagc aaaaactgct ggtaatctct taactgcccc ttgtgttcat agcgaggata
    22021 agcatatttg acaaagtcta cctgcttaaa gcgactcagt ttcatctgat tgccttcatt
    22081 ccaattttcc ccatgggttt caaaagcaaa aatggtggcc aactggaaac cgtattcggt
    22141 tttcatctcc tgagcaacct ctaaaaccca atattcaaaa cccaaacttc ctgtaaacac
    22201 aagccaagac accccatctg ctgccatagc ctctaaatct ttacgtatcg cttttttaat
    22261 caatttaaga cgaggatcct tatcagaaaa taaacccaaa tcaaaagcag aatagcctaa
    22321 aaccaaagct gtagccattt ttaacccttt ctgtgcaaat tatggtataa taaagtgatg
    22381 ttattgtacc aataaggaga attatggtca actatccaca taaagtttca tcacaaaaaa
    22441 gacaaacatc tctttctcaa cccaaaaatt tcgcaaatcg aggaatgtct tttgaaaaga
    22501 tgatcaacgc taccaacgac tactatttgt ctcagggctt ggctgttata cataagaaac
    22561 caactcctat tcaaatcgta caagtggact atccacaacg aagtcgtgcc aagattgttg
    22621 aagcctattt tcgacaagct tcaacgacgg actattctgg cgtttataat ggatattaca
    22681 tcgactttga agtcaaggaa acaaaacaaa aacgtgcgat tccgatgaaa aattttcatc
    22741 cacatcagat tcagcatatg gaacaagtcc ttgcccaaca aggaatctgc tttgtccttc
    22801 ttcacttttc ttctcagcaa gaaacctact tattgccggc attcgatttg attcgcttct
    22861 atcatcaaga taagggacaa aaatcaatgc cacttgaata tattcgagaa tatggatatg
    22921 aaatcaaggc tggtgccttc cctcaaattc cttatctcaa tgttatcaaa gaacatttat
    22981 taggtggtaa aacaagatga acaaaccaac gattctgcgc ctaatcaagt atctgagcat
    23041 tagcttctta agcttggtta tcgcagccat tgtcttaggc ggaggagttt ttttctacta
    23101 cgttagcaag gctcctagcc tatccgagag taaactagtt gcaacaactt ctagtaaaat
    23161 ctacgacaat aaaaatcaac tcattgctga cttgggttct gaacgccgcg tcaatgccca
    23221 agctaatgat attcccacag atttggttaa ggcaatcgtt tctatcgaag accatcgctt
    23281 cttcgaccac agggggattg ataccatccg tatcctggga gctttcttgc gcaatctgca
    23341 aagcaattcc ctccaaggtg gatcaactct cacccaacag ttgattaagt tgacttactt
    23401 ttcaacttcg acttccgacc agactatttc tcgtaaggct caggaagctt ggttagcgat
    23461 tcagttagaa caaaaagcaa ccaagcaaga aatcttgacc tactatataa ataaggtcta
    23521 catgtctaat gggaactatg gaatgcagac agcagctcaa aactactatg gtaaagacct
    23581 caataattta agtttacctc agttagcctt gctggctgga atgcctcagg caccaaacca
    23641 atatgacccc tattcacatc cagaagcagc ccaagaccgc cgaaacttgg tcttatctga
    23701 aatgaaaaat caaggctaca tctctgctga acagtatgag aaagcagtca atacaccaat
    23761 tactgatgga ctacaaagtc tcaaatcagc aagtaattac cctgcttaca tggataatta
    23821 cctcaaggaa gtcatcaatc aagttgaaga agaaacaggc tataacctgc tcacaactgg
    23881 gatggatgtc tacacaaatg tagaccaaga agctcaaaaa catctgtggg atatttacaa
    23941 tacagacgag tacgttgcct atccagacga tgaattgcaa gtcgcttcta ccattgttga
    24001 tgtttctaac ggtaaagtca ttgcccagct aggagcacgc catcagtcaa gcaatgtttc
    24061 cttcggaatt aaccaagcag tagaaacaaa ccgcgactgg ggatcaacta tgaaaccgat
    24121 cacagactat gctcctgcct tggagtacgg tgtctacgat tcaactgcta ctatcgttca
    24181 cgatgagccc tataactacc ctgggacaaa tactcctgtt tataactggg ataggggcta
    24241 ctttggcaac atcaccttgc aatacgccct gcaacaatcg cgaaacgtcc cagccgtgga
    24301 aactctaaac aaggtcggac tcaaccgcgc caagactttc ctaaatggtc tcggaatcga
    24361 ctacccaagt attcactact caaatgccat ttcaagtaac acaaccgaat cagacaaaaa
    24421 atatggagca agtagtgaaa agatggctgc tgcttacgct gcctttgcaa atggtggaac
    24481 ttactataaa ccaatgtata tccataaagt cgtctttagt gatgggagtg aaaaagagtt
    24541 ctctaatgtc ggaactcgtg ccatgaagga aacgacagcc tatatgatga ccgacatgat
    24601 gaaaacagtc ttgacttatg gaactggacg aaatgcctat cttgcttggc tccctcaggc
    24661 tggtaaaaca ggaacctcta actatacaga cgaggaaatt gaaaaccaca tcaagacctc
    24721 tcaatttgta gcacctgatg aactatttgc tggctatacg cgtaaatatt caatggctgt
    24781 atggacaggc tattctaacc gtctgacacc acttgtaggc aatggcctta cggtcgctgc
    24841 caaagtttac cgctctatga tgacctacct gtctgaagga agaaatccag aggattggaa
    24901 tataccagag gggctctaca gaaatggaga attcgtattt aaaaatggtg ctcgttctac
    24961 gtggagctca cctgctccac aacaaccccc atcaactgaa agttcaagct catcatcaga
    25021 tagttcaact tcacagtcta gctcaaccac tccaagcaca aataatagta cgactaccaa
    25081 tcctaacaat aatacgcaac aatcaaatac aacccctgat caacaaaatc agaatcctca
    25141 accagcacaa ccataacatt tatcatccag atttttctgg gtgatttttt catagcacta
    25201 ttgtatttat gtgcttaaca aaagcctgag aagatatctt ctcaggcttt ttctgtacta
    25261 taaacctcat tggaaaagat agagactgct tccgtaatct tgttaagagg ttttactaaa
    25321 tactagtctt tcttcgtttt tactacaaag agagcagata gggctaggct aacacttgct
    25381 aggaagaggg ctgtgtcaga ttgactctca cctgttgctg gcaagatttg ttcaggtgtt
    25441 tctggtctag ctatttcttg cttataatct ggcgtcttac cttgatcgga agctaaagat
    25501 ctaagtttaa actcaggttt ctctacagtt ggagcatctg gtttcgtagc agaatctttt
    25561 aattggttga gataatctgc aaagtattcc accattcttt ccgtcaagag atggttattc
    25621 gtcgcatatt tcatgcttgc ctgaacgcta gctacttcct cttgattgtc tttgtctgtt
    25681 aatttctgag ccttagccaa agctgcttca tagcctgaca agtcaagagg tgtttctgct
    25741 acctgtggac gagtaaagat gagttccgct gcagattggt atttatcgcc accatctccg
    25801 taagtcttag tacctgtaag gacaattttc ttagccttaa ttgtcttacc aaaatcaatg
    25861 tcttttggct tattgttatc tggccaatca gttgcagtaa aggtatgctc cttgccagac
    25921 tcatctgtca caacaagttt cacatcacgc aagttaccat ttgaacctga tccacgtgga
    25981 acataacgaa gtccagtgat ttcagttgct tctttcaaga ccatggttgc aggcttgcct
    26041 acatctcctc cgccccatga tgtatgccat aaactagata agtttccatc aaaggcattt
    26101 gcaagacctt cttgagcctg agcaggagct gtaagacttg caaagtcatc tgctaccaaa
    26161 gccgttttct tctgaaccaa agcattcttc aaggcttcaa tcttggcaat ctctgcacgc
    26221 gcttcttcca cactgatatc atcatcggcc tgactgaggt taaagaccgc ctctttcaaa
    26281 gcatccatag actctttggt gtagttagtc atggcaaccg ttggcaagta gttcttcaga
    26341 gcattttctg tcaacatctt acctgttagg gtaatttctt cgatttgaag attatccatc
    26401 atgaagtcgt tataaccacg gaagttggca tttccaccag aatcaccacg agtattactt
    26461 gcatttccag ttgagtagat acctacccaa gtatcccctg tttctgcacc tgtcacgagg
    26521 aaggttgcct tcttggcttt cttagaatct gtccaagtat ttggcaattc atgcatttcc
    26581 aagttgcttg cttgagtgcc acgacgacct gactggaatt ctcccttacc gactacaaaa
    26641 gcataggtat tgtctgaacc tgcttcgtat tcaaaggtta cacggtaggt cttacctgct
    26701 tcaaaacgga agttttgcgg aatagtttgg taaaccaagt tacgacggct cactagtcca
    26761 tttgtcttga gtgaccaatt tccttcgata acatcatcga ctttcttacc attccaacca
    26821 cgttgtgtat atggatagtg tttttcagac aagtgagtgc ggttatcttc aacaccttca
    26881 acaccaccca ctacaaatgg gaagataccc tgagcaacat tttcaaagtc ttgcttgaag
    26941 gtgcctttac ctgtatcatg cttgtctcca tacatgcttg aattgttttc aaaggtacga
    27001 atttcatcaa agtaagttgc ttgatcacca gcttcacgac tcaatgtcag agtaacattt
    27061 gagacgtccg atcctgttgt aaagaaggcg tacatgtttt ggaagtaact tgtatcgtta
    27121 actgtagcat tgtcacgacg tgtattgtgg gcgtaagcct taacatagtt gaacgcgaga
    27181 gacttattgg tataagtagt cacttctttt tcaccagtat ttacagtgat gctcgccttg
    27241 gcattactac ggttatcgac accgacataa acggcatact tggtatttgg tttcaagcca
    27301 gttaatttct gagtgagact aactttttct ttgtttcctt gaatacgaag catatcgttt
    27361 gccccttgag acttgacaat ttctgcctta gaagcatcgc ctgaaatggt ccaatgtttc
    27421 aaggtaccac tgttaaatcc ttggtcatag atgtgcatgc cttcactcca tgacatttca
    27481 ggattggttt gttttgaacg atagagaacg tatggttgat ttgctagaag atctagggta
    27541 attttaccat cttttacagt tagttcttgc tcttctgtct taccttggtc agttagcttg
    27601 taaaggtaaa ccttgctctt tgcccaatcg cttggaaggg tccaagttgt tgcaccggcc
    27661 tgcgtattga agtagtacat cttttccttc tcagtagaaa gtttcttacc atttgcatcc
    27721 cagttccaag gagtcaagta agctgaacca tcttggatga cacgtccgtt gagagttact
    27781 gtacgttcgc gatattgtgg gctattgaca tcatttgact tacgagttac aactacttta
    27841 ttattgtcag catctaccaa ttccactcgc atttctggag tccatttata ggtgctaccg
    27901 ttatcggtca tagtcaccgg tgtaccattt tcccatttac ttacagtgaa gtgttggaaa
    27961 tacttggtca tgacatcatg ggcaaagagg ttagtcacgt agccattgta gtcgctccgt
    28021 ccttgccagc cttcaaagtc tttcatgctg tagccaccta gcagtggata gttggctgca
    28081 ccaccataac ttctgtagtc cccaacccaa gcatcttttt ggtggttacg gataaagcgg
    28141 gtgatggcac tgttgatacc tttattggtg tagccaccgt aggtcaagtc agctgcccag
    28201 tgatggaagg tagagtcgta ctcaccacca tggccccact cgatcgcaaa gcgccagcct
    28261 tgtttgttaa tttctttggc aagaacgtgg gtagcccagg caccgttatc acctgattga
    28321 ccattacccc aaacgtccac atagataaag tcgagaccgt caccaagttt tttcttcaaa
    28381 tcttcccaac gtgccaaacg accatgagct aggtcatagg cagcatcaat gttgatacct
    28441 tgatctagcc agttccaacc atagctatag cttccatctg gattcttacg gagaattttt
    28501 tcattgaagt atttagactc aggataagtt tctgaagcgt taacgtggat acctagatga
    28561 gctccatatt tcttagcctt ctcaattagg gtcttgaaat cttcgacacc accgatacgc
    28621 ttaccaatat cagcatagtt caagtgacca gagtcatggc cttcgctacc atatccttta
    28681 aggagaacac cttgcccaag accatctgtg tggagattga ttttcttgat accatccaag
    28741 gtcataagga atgggttttg tgcttgagaa ccaaagttca tcgcgatacg gtaagctgtg
    28801 atatccttaa ctttttccca accttgaggg ttgttcataa tgctacgata agcaatggca
    28861 ccatcttgcc aatcaacttt cttgtctgca ttggcatctt cagtgataac aaccttagca
    28921 cttggaagtt ccttcgtgta ttctgggaaa acaatgccct tataagcttt ttcccattgc
    28981 cattcagagc tgtggattcc tacatagttg gcatttccga ctgtttcttt ataagctgtc
    29041 aaacgagtcc agtcattcga accaccacca tagctatttt gagagttact ccaaacacca
    29101 gcagcaagct tatctgtaga aacaaatcca tacatgtaac ccttagccaa atccttcatt
    29161 ggattggtta catcgatatg atcatctccg ctgacatgcg tattgtttga catggttgcc
    29221 ccatcaaact tagcaccagt ttgatcacta gaaacagaga ctaaagcatt gccgaggaaa
    29281 ctaatagaag aaagtagttt tctttcgtca tcaatctttt gacctggagt gacttgattg
    29341 tggttgacaa tcttggtcac atcaaagtgc aattgattgt ccacaacttg caagcgtact
    29401 gtcatttccg cattgattaa gtgagcatca tcgcgaagct tcatcaagta ctctgctgtt
    29461 gtctcattga tttttttata agtgacttca ggggtgattc ggtggttatt gataaagact
    29521 tggttgaatt gttgcacctg tcctggcaaa gtatgtccat tcaaggtgta ttccttgaca
    29581 cgagggaagg cttggtcaat tactgcctta agtaccttag actggatcgt atcataagtc
    29641 acctttctat cgtcaacaac cggacctgtt tctttctggg caggggtatc ctctgttttt
    29701 accctctctt ggttatccgt tttaacgcta acaactgttc gctcatcgtc ataagagccc
    29761 gccttgagaa gaatcttctt ctcattttta agatggtcat tgaccgcagc tggtagagtc
    29821 actgtgtcaa agagattgac atcgttattg ctggcattta gctgaccgtc tgacttgaga
    29881 gtgatagaga gacggtttgt tgatcctgtt tcaggagcag caacacgact acctctatac
    29941 caagtgctag ttgttggaga tttatactcc cagaaccagc catccttgtc ataaccgaca
    30001 aaaacattat tattggtatc tttaaatttc aggaagacac caaagcgtga tttgcccttt
    30061 tcagaatctt ctttgaaggt taaatcaaca gttgcatttc cattggcatc aacggtcaag
    30121 cccttctttt caaacagggc tggtttgcct gcgttatcat tttgagcagt tgaggatagt
    30181 tggttgtagc ggacaccttt ttcttctcgg atagtgactg ttccctgttg ctctttattc
    30241 gctaccgttt gccattcagg ggttaccgtc ttaggtgttt caggtttagc agctgcaggt
    30301 ttatcctctt ttggtttttc ttcagctggt ttttcttttt caagtgctaa tagttcttct
    30361 tctgtcttag gtccatctgt aacttctgga gaaccttggt cttctcccac cttaggcgct
    30421 tcaaaatcac gcccatcatt ctcttttgct gttgcaagag cagtagctaa atcagctggt
    30481 aagttcgccg tggaaccaga ctgcacgcta tctgcaagaa ccggacttgt cccaaagaat
    30541 gcagctccaa tcataacaga agcaacacct aatgaaaatt tccgaatact atatttacaa
    30601 cgtttttcaa ataatccttt attcataaac ttctaaatcc tttcattttt gggcaagcgt
    30661 ttacatttcc tttttaaaaa atactccttc ctctgaaagt gcaatgctta accctgataa
    30721 ataaaaaata attatacttt taatataaca aataataact gataaagcaa taggaaacaa
    30781 gtaaaattaa caaaaatttt ctctattctg acaaaaagag gctccaactt ttggggggca
    30841 gtacatttag aatctttctt tacaaatgta aaaaaggatt cagcattcaa gagaaatact
    30901 aaatcctttc ttatattttg caacagttat ttcacatgtt ttgcgagatc ttcttgagcc
    30961 tttttattag actcttcttt ttctttcatc catttttcct gagctttttg gtattcatct
    31021 acagtgactg ccttgtcttg aagttccaag tatttataca agactggttc acttgtacct
    31081 ttatttcctg acaatgcaaa tggtattgta aatggtacca tcttagacaa gattggacgc
    31141 cctgtacgag atgtagttgg aataatcaaa gcactatctg tcaaccaagc ttgggctgca
    31201 gcgtatttat catagcgttt agcaacatct gtagtctcat caccagcctc agtaaccaat
    31261 ttttcgtagt catatagacc tactttttta gcagctacat tatcttcccc tgagtcaaac
    31321 cctaaatatg ttttagtact ttctcctaca gatggtttga tgatatcaag gtaggttgat
    31381 ggatcggcaa agtctggacc ccaaccgaca ttatctgata aatcccagtc ttcgccagca
    31441 gcattttcag caaaatatgt aatattgttt acttcgtctt tttgtagttg ttgaatatca
    31501 atgactacat tatccgctcc taaagttgct tccaaggatt gtttcataga ttggacgcgc
    31561 tgaacttttg tagttgctgt ttggtcaact ggcatatcca aatgaattgg gaatgtcaca
    31621 ccttctgctt gtaaggctga tttagcttta gcaaattcag ccttggcttt ttctggattg
    31681 taaagaccat cctgagaatc tgcaagatta acatccttcc attcatcccc ataagtaacc
    31741 aatttctctt tgaccatatc gccaaagttt ttaccatctg cttgaacaaa tgttggtgga
    31801 acaaagatat tacgtaagat tttgcttgct ccagtttgtc cattcaactg agaggcatag
    31861 gctgtacgat caaaaccaaa ggcaatagcc tgacggaaat ccttgtttaa gagagccttt
    31921 ttagtcgatg ccttttgttc gtcgctggtc ttagatgtgt atttatagga ctgacggtca
    31981 atatttgtac caactagata cgtaatagag tcttgttgag tatagacaat attgtccttc
    32041 atactcttct caagctctgc gaaacttgca cttgttggat agagacgagc tgctgtaagg
    32101 ctaccatctt taaagttttc tgcaggtttg ctggtatctt gaccatccca gaatgacaat
    32161 ttaactttgt caatatgcac attgtcctta tcccagtagt tcggattttt cgcaaattca
    32221 acagaagatt tggtcacaat ggatttcaac aaataaggac cgttatacaa gagactactt
    32281 ggatccgtag ctttggcaaa atcatcccct tttgaattca aaaactcttc attaactggc
    32341 gcaagcacac ccatggttgt cttagaattc cagaagcttt ctggtttgtt caaagtgtac
    32401 tgaactgtct gttcatccag agccttaatt tctacttgtg agaaatcgtt gatttcccct
    32461 tttacatagg catccaaccc tttgattgat tcttgaacaa ggtaaagagc atctgatttt
    32521 ttatcagcag catattttag tcctgttaca aagtcttgag ctttgactgc tgcgtattct
    32581 tcaccttcag aagtatacca ttttgcatcc ttacggatag tataagtgta agtcaatcca
    32641 tccttggata cagaccaatc ctcagccata gacggcacaa agttcccgta gcgatcattt
    32701 tctagcaaac catcaaccac gttactggta atatttgctg tcgcagcctt agcagttgtc
    32761 aaatagttga ggttatcagg gtctgtctca taaatgtatg agaatgtctt ctcaccttta
    32821 gtgcttgaac ctgatccaga gcatgcagct aaagtagtcg ccgccaataa tgtcacgccc
    32881 gcaagggcaa atagttttga acttttcatc attttctcct ttaaaacttt ctctccatta
    32941 tagactcttt tcagaaagat gtcaacagaa ttttcagaat ttttgaaaat tatttttcaa
    33001 acaacatctt tgcaaaaaat atgaatatca tttaaaaatc cctcaactat atcacatagt
    33061 caaggaattt ttaatactat ttctaaataa taactggtag tcagttttac ttgtttatac
    33121 tcttcgaaaa tctcttcaaa ccgcgtcagc ttccatctgc aacctcaaaa cagtattttg
    33181 agcaacctgt ggctagcttc ctagtttgct ctttgatttt cattgagtat taatctaact
    33241 catttctcac gcactgcaaa gcggctccaa ttacttggtg catatcgtaa taacgataat
    33301 gtcctaagcg gccaccaaag ataacattcc cttgctcatc agcaaatttt ttatacgatt
    33361 tatacaaatg attattacga tcattattaa ctggataata aggctcatca cctttttccc
    33421 atgttttaga atgttcttta gtaatgatgg tctttgcttg actcccaaac tcaaaatgtt
    33481 tgtgttcaat aatgcgagta tatggggttt ctgcatccgt atagttcaca actgcatttc
    33541 cttggtaatt ttccatatcc aaggtctcat tttcaaaacg aagactacgg tactctagtt
    33601 cgcccaactt atagtcaaag aattcatcaa tcataccagt aaagacaatc ttaggaaaat
    33661 ctttcagata ttgctcttta ttcacaaaga aatcaacatt tgtttctaca tcaatatttt
    33721 catgatccaa cattttttca actatttgag tgtatccacc aattggaatc ccttgatagg
    33781 tatcgttaaa atagttgtta tcataggtca ggcgtaccgg caaacgacga ataataaagg
    33841 ctggaagttc agtagtcggt ttgccccact gtttctctgt atagtctttg attaattttt
    33901 cgtagatgtc tgtacctaca agagaaatcg cctgttcttc caaattttca ggagttttac
    33961 catttaaaat agcacgttgt tcatcaatct tagcttgtgc ttctgctggc gtcacaactc
    34021 cccagagttt attgaaggta ttcatattaa aaggtaagtt ataaatctct cccttatagt
    34081 ttgcaacagg agaatttgta taacggttaa actctgcaaa ctggttcaca taatcccaga
    34141 tctccttatc agaagtatga aagatatgag caccatactg atgaacttga attccttcct
    34201 cttcacgagt atagatatta cccgcaatat gatttcgttt ttcaataact tttacttttt
    34261 ttccttttaa ggctgattca tgggcaaata ctgcaccaaa aagaccggca ccaacgataa
    34321 gataatcgta catcttatgc tcctttttat aatttgacaa ttcgattgaa gtaaggaatc
    34381 ttcattaaca ttccagtaat aataaaacta acacttaaag taaatagagc aaaaagcaaa
    34441 tatgctccta caaaattaaa accaaatagt ttttcccaca ctttaataat ataagtatgt
    34501 attataaaaa ctcccattgt ttgattagaa agggaaacaa tcgattctct tcggttttca
    34561 ttcaaagtaa gcgtgaggat agttagaaaa attcctagag tactgacttt tacaaataaa
    34621 gtatcataaa agtattcagc aaatagatta tggtatatag tcttcgctat gaaaaataat
    34681 attattggtg aaatcaataa caaaagtatg ctaactattt tcatccaatt tttaaacctt
    34741 gattcgattt cttctatagt gaattgcgct ataaaaccac ctaaaatata atagaaaaac
    34801 ccagtccata atctgaaagt ttgtacaaca tatgtttgta ttggcatctg aagtaagata
    34861 tttgataact caaaaatcaa accaataatc agcaataaag acagactgta taaatagctt
    34921 ctttttgaat ttagaaattt tctcaaaatt ggtaaacata aatagataag tattagtgca
    34981 ccgaaaaacc aaaactgagg gaaataatct ctttgtatca aagaacctac aattttttta
    35041 ataggattag ttgtaaaatc acgcttaaaa atccatacga taaatgtcca tgatgacact
    35101 gttattaaaa tccattttac tttctggagt atgtaatgat aagttatttc cctcttgcct
    35161 aacaataaat aaccattgac cataaaaaac aggggaatag agtaggtact taaataatat
    35221 aaatatgcca aaagattcca tgagtcggtc tctttaaatc cggccattgt tgtatgaagt
    35281 aaaacaactc caacacatgc aagcactttt agtaaatcta agttaatatt tcgaattttt
    35341 ttcattctaa tttttcctaa taatttgttt taattctttc acatctacca ctttcagaga
    35401 tagaattgca aaaagataaa ttattccacc aagcgctgca aatgctagaa catttaaagt
    35461 cggtgaaaaa tgtataactg tttttgaact tagtaaaagt ccatacataa tggtagatgc
    35521 tagtataatt tttgccattg atccgattat aggaactcct tttaaatatc tgcgagtata
    35581 gaacaattgg attgcccata caaatgcctc tgttaaaacc gagacaatgg ctgccccgat
    35641 ataaccaaac tttggcagga atagcaagtt taaacctaca ctgataattg caggagcagt
    35701 tgttgaaatc atgaattctt tattttgatt atgaggtatc agcatctgaa ttcccatgat
    35761 gttagtccaa ccgataaaga acatccgaaa aatcatgatg gcaattgcat aacgcgcatc
    35821 ctgaaaatct tgcccaagga aaaattgaac aaaatcatca ttcacaatca aaatcactac
    35881 tatcactgga aaaatcacta aattataaat gaggaaggat atctcatgca ttttattaac
    35941 cgctttttgt tcccctttgg atagcagatg cgcaacacga ggtaacataa cgcttcccaa
    36001 agaagttacc agggtcataa ggatattgac caactttaga gcctggtcat aaatccctac
    36061 atcttttgta gaagctaatg ctccaagcat ggtacgatct aacgtaatat acatagaaat
    36121 agctacttga ggaaggaata ataatatgac aggtttcaaa tgatgtctaa catatgctat
    36181 atcaaaatga tctctaccaa taaattctcg agcaggcaac cacatactta gttgtcctaa
    36241 gagttcaaat atggttagta aaaagatata gagataaagg tcactttcag atttgacaaa
    36301 aaggaagata gagattacac ctatcagttt aaccgtgata tttcgaacag ttatctttct
    36361 aaaatcctct aacccttgaa agagccaaga aatatctaag cctttagaaa ccacactcaa
    36421 tcctagaata taggcgactg gattttgcat caaagaaaga gttagacaaa gaacaacgta
    36481 taaggacaga gacagaactg ccgcacacaa ttgcagggag tagattcccc aaaagttttt
    36541 ttcaatttcc tttcgatttc cagagattac cttagtacca tagttagcaa ctcctagagt
    36601 agctaagagg ataaaataag taacgatgga attaaaataa ccataagtcc ctaaagcata
    36661 cgaagaaaag actcgtgtca catagggagt tgtaatgatt gggagtataa tcaccaacaa
    36721 ttgataagaa agattgtagg cgtagttttt taagattttc attttaaaga gaaactccta
    36781 cttggttttt atagtgtgtt gaaataaa
//
LOCUS       DBEJAU010000014        35176 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC323 isolate 683620
            SAMN38261939-rid24807223.denovo.014, whole genome shotgun sequence.
ACCESSION   DBEJAU010000014 DBEJAU010000000
VERSION     DBEJAU010000014.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261939
            Sequence Read Archive: SRR26833919
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 35176)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 35176)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576303.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576303.1
            Genome Coverage       :: 154x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/19/2025 01:05:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,121
            CDSs (total)                      :: 2,078
            Genes (coding)                    :: 1,943
            CDSs (with protein)               :: 1,943
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 36
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 72 of 135
            Pseudo Genes (incomplete)         :: 63 of 135
            Pseudo Genes (internal stop)      :: 51 of 135
            Pseudo Genes (multiple problems)  :: 46 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..35176
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261939-rid24807223.denovo.014"
                     /strain="GPSC323"
                     /isolate="683620"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            complement(1..1449)
                     /locus_tag="ACL29Z_000771"
                     /pseudo
     CDS             complement(1..1449)
                     /locus_tag="ACL29Z_000771"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_050084071.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing N-terminus and C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(1448..1642)
                     /locus_tag="ACL29Z_000772"
     CDS             complement(1448..1642)
                     /locus_tag="ACL29Z_000772"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000691852.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HGR0069109.1"
                     /translation="MKIIQQQSAIIDSLTNELSLLCEQVAYLTQKLSGKSSEKSVCPF
                     GQLNLFEEESPSEKDGDVPS"
     gene            complement(1813..2163)
                     /gene="tnpB"
                     /locus_tag="ACL29Z_000773"
     CDS             complement(1813..2163)
                     /gene="tnpB"
                     /locus_tag="ACL29Z_000773"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001846105.1"
                     /note="TnpB, as the term is used for proteins encoded by
                     IS66 family insertion elements, is considered an accessory
                     protein, since TnpC, encoded by a neighboring gene, is a
                     DDE family transposase; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS66 family insertion sequence element accessory
                     protein TnpB"
                     /protein_id="HGR0069110.1"
                     /translation="MTIHLSSLGQVYLVCGKTDMRQGIDSLAYLVKTHFELDPFSGQV
                     FLFCGGRKDRFKALYWDGQGFWLLYKRFENGRLTWPSTEKDVKALTPEQVDWLMKGFS
                     ITPKINLSESRDFY"
     gene            complement(2144..2329)
                     /locus_tag="ACL29Z_000774"
     CDS             complement(2144..2329)
                     /locus_tag="ACL29Z_000774"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001136123.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0069111.1"
                     /translation="MPQPIVPVEIPQSRPFDSKKRNDILLKIRIGKLELSFFQSLNLE
                     MVEQLLDKVLLYDNSSI"
     gene            complement(2633..4195)
                     /gene="guaA"
                     /locus_tag="ACL29Z_000775"
     CDS             complement(2633..4195)
                     /gene="guaA"
                     /locus_tag="ACL29Z_000775"
                     /EC_number="6.3.5.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000065723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003922 - GMP synthase
                     (glutamine-hydrolyzing) activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016462 - pyrophosphatase activity
                     [Evidence IEA];
                     GO_process: GO:0006177 - GMP biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine-hydrolyzing GMP synthase"
                     /protein_id="HGR0069112.1"
                     /translation="MSNISTDLQDIEKIIVLDYGSQYNQLISRRIREIGVFSELKSHK
                     ISAAEVREVNPVGIILSGGPNSVYEDGSFDIDPEIFELGIPILGICYGMQLLTHKLGG
                     KVVPAGDAGNREYGQSTLTHTPSALFESTPDEQTVLMSHGDAVTEIPADFVRTGTSAD
                     CPYAAIENPDKHIYGIQFHPEVRHSVYGNDILRNFALNICKAKGDWSMDNFIDMQIKK
                     IRETVGDKRVLLGLSGGVDSSVVGVLLQKAIGDQLICIFVDHGLLRKGEADQVMDMLG
                     GKFGLNIVKADAAKRFLDKLAGVSDPEQKRKIIGNEFVYVFDDEASKLKDVKFLAQGT
                     LYTDVIESGTDTAQTIKSHHNVGGLPEDMQFELIEPLNTLYKDEVRALGTELGMPDHI
                     VWRQPFPGPGLAIRVMGEITEEKLETVRESDAILREEIAKAGLDRDIWQYFTVNTGVR
                     SVGVMGDGRTYDYTIAIRAITSIDGMTADFAKIPWEVLQKISVRIVNEVDHVNRIVYD
                     ITSKPPATVEWE"
     gene            4337..5035
                     /locus_tag="ACL29Z_000776"
     CDS             4337..5035
                     /locus_tag="ACL29Z_000776"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000936186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HGR0069113.1"
                     /translation="MLPAYMKIHDQIKKNIDEHRWAIGERLPSERDLAEQFAVSRMTL
                     RQAVSLLVEEGVLERRVGSGTFVSSTRVQEKMRGTTSFTEIVKSQGKVPSSQLISYKK
                     TIPNEQEVTKLGIFPTDNIIRMERVRYADQVPLVYEVASIPEKFIKDFKKEEITSHFF
                     QTLQKHGYRIGKSQQTIYARLAKEKIAHYLEVEKGHAILGLTQVSYLEDGTAFEYVKS
                     QYVGERFEFYLENN"
     gene            complement(5078..5974)
                     /locus_tag="ACL29Z_000777"
     CDS             complement(5078..5974)
                     /locus_tag="ACL29Z_000777"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000071673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DMT family transporter"
                     /protein_id="HGR0069114.1"
                     /translation="MSNSLKGTLLTVVAGIAWGLSGTSGQYLMAHGISALVLTNLRLL
                     IAGGILMLLTYATTKDKILVFLKDRKSLLSLLIFALIGLFLNQFAYLSAIQETNAGTA
                     TVLQYVCPVGILIYSCIKDRVAPTLGEIVSIILAIGGTFLIATHGQLDQLSMTPVGLF
                     WGLFSALTYALYIILPIALIKKWGSSLVIGVGMVIAGLVALPFTGVLQADIPTSLDFL
                     LAFAGIILIGTVFAYTAFLKGASLIGPVKSSLLASIEPISAIFFAFLIMNEQFYPIDF
                     LGMAMILFAVTLISLKDLFLEK"
     gene            complement(5983..6918)
                     /locus_tag="ACL29Z_000778"
     CDS             complement(5983..6918)
                     /locus_tag="ACL29Z_000778"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000872223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine hydrolase domain-containing protein"
                     /protein_id="HGR0069115.1"
                     /translation="MKWTKIIKKIEEQIEAGIYPGASFAYFKDNQWTEFYLGQSAPEH
                     GLQTEAGLVYDLASVSKVVGVGTVCTFLWEIGQLDIDRLVIDFLPESDYPDITIRQLL
                     THATDLDPFIPNRDLLTAPELKEAMFHLNRRSQPAFLYSDVHFLLLGFILERIFNQDL
                     DVILKDQVWKPWGMTETKFGPVELAVPTVRGVEAGIVHDPKARLLGRHAGSAGLFSTI
                     KDLQIFLEHYLADDFARDLNQNFSPLDDKERSLAWNLEGDWLDHTGYTGTFIMWNRQK
                     QEATIFLSNRTYEKDERAQWILDRNQVMNLIRKEE"
     gene            complement(6915..7640)
                     /locus_tag="ACL29Z_000779"
     CDS             complement(6915..7640)
                     /locus_tag="ACL29Z_000779"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001102210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CppA family protein"
                     /protein_id="HGR0069116.1"
                     /translation="MNVNQIVRIIPTLKANNRKLNETFYIETLGMKALLEESAFLSLG
                     DQTGLEKLVLEEAPSMRTRKVEGRKKLARLIVKVENPLEIEGILSKTDSIHRLYKGQN
                     GYAFEIFSPEDDLILIHAEDDRASLVEVGEKPEFQTDLASISLSKFEISMELHLPTDI
                     ESFLESSEIGASLDFIPAQGQDLTVDNTVTWDLSMLKFLVNELDIASLRQKFESTEYF
                     IPKSEKFFLGKDRNNVELWFEEV"
     gene            complement(7724..8359)
                     /locus_tag="ACL29Z_000780"
     CDS             complement(7724..8359)
                     /locus_tag="ACL29Z_000780"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000290646.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SGNH/GDSL hydrolase family protein"
                     /protein_id="HGR0069117.1"
                     /translation="MAVQLLENWLLKEQEKIQTKYRHLNHISVVEPNILFIGDSIVEY
                     YPLQELFGTSKTIVNRGIRGYQTGLLLENLDAHLYGGAVDKIFLLIGTNDIGKDVPVN
                     EALNSLEAIIQSVARDYPLTEIKLLSILPVNEGEKYQQAVYIRSNEKIQNWNQAYQEL
                     ASAYMQVEFVPVFDCLTDQAGQLKKEYTTDGLHLSIAGYQALSKALKDYLY"
     gene            complement(8361..9188)
                     /locus_tag="ACL29Z_000781"
     CDS             complement(8361..9188)
                     /locus_tag="ACL29Z_000781"
                     /EC_number="3.-.-.-"
                     /EC_number="3.1.3.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HGR0069118.1"
                     /translation="MMIKVIATDMDGTLLDARGQLDLPRLEKILDQLDQRGIRFVIAT
                     GNEIHRMRQLLSPLVDRVVLVVANGARIFENNELIQAQTWDDAIVNKALAHFKGRACQ
                     DQFVVTGMKGDFVKEGTIFTDLESFMTPEMIEKFYQRMQFVDELTSDLFGGVLKMSMV
                     VGEERLSSVLEEINALFDGRVRAVSSGYGCIDILQAGIHKAWGLEELLKRWDLKSQEI
                     MAFGDSENDVEMLEMAGIAYAMENADEKAKAVATALAPANSQGGVYQVLENWLEKGE"
     gene            complement(9210..9545)
                     /locus_tag="ACL29Z_000782"
     CDS             complement(9210..9545)
                     /locus_tag="ACL29Z_000782"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398793.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="poly-gamma-glutamate biosynthesis protein"
                     /protein_id="HGR0069119.1"
                     /translation="MGNFISNQRIESMGDEENAKWTERGVLMDVTIKKKDGKTTIGTA
                     KAHPTWVNRTPKGTFSPEGYPLYHYQTYILEDFIEDGSHRDQLDEATKERIDTAYKEM
                     NEHVGLKWY"
     gene            complement(9546..10262)
                     /locus_tag="ACL29Z_000783"
     CDS             complement(9546..10262)
                     /locus_tag="ACL29Z_000783"
                     /EC_number="3.1.-.-"
                     /inference="COORDINATES: protein motif:HMM:NF021127.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042578 - phosphoric ester hydrolase
                     activity [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0045227 - capsule polysaccharide
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="CapA family protein"
                     /protein_id="HGR0069120.1"
                     /translation="MAHGDLLYHDGLFFSAKKEDGTYDFHENFEYVTPWFKQADLAIG
                     DFEETINKDHYLAGYPLFNAPAEVMDAIKEAGYHVLDLAHNHILDSQIEGVISTADII
                     EKAGITPIGVYTHEPRDQAPLVIKEVNGIKVALLAYSYDFNGIEQYISQEDYNRYLSD
                     LNEDKMKVEIERAEKEANITIIMLQMGVEYRLEPTEEQKALYHKMIDWGADIIFGGHP
                     HVVEPSETVEKDGDKKLIIY"
     gene            10785..11396
                     /gene="def"
                     /locus_tag="ACL29Z_000784"
     CDS             10785..11396
                     /gene="def"
                     /locus_tag="ACL29Z_000784"
                     /EC_number="3.5.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015058782.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042586 - peptide deformylase activity
                     [Evidence IEA];
                     GO_process: GO:0036211 - protein modification process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptide deformylase"
                     /protein_id="HGR0069121.1"
                     /translation="MSAIERITKAAHLIDMNDIIREGNPTLRAIAEEVTFPLSDQEII
                     LGEKMMQFLKHSQDPVMAEKMGLRGGVGLAAPQLDISKRIIAVLVPNIVEEGETPQEA
                     YDLEAIMYNPKIVSHSVQDAALGEGEGCLSVDRNVPGYVVRHARVTVDYFDKDGEKHR
                     IKLKGYNSIVVQHEIDHINGIMFYDRINEKDPFAVKDGLLILE"
     gene            11441..12169
                     /gene="rlmB"
                     /locus_tag="ACL29Z_000785"
     CDS             11441..12169
                     /gene="rlmB"
                     /locus_tag="ACL29Z_000785"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006151108.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008173 - RNA methyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0006396 - RNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA
                     (guanosine(2251)-2'-O)-methyltransferase RlmB"
                     /protein_id="HGR0069122.1"
                     /translation="MKTNDIVYGVHAVTEALLANTGNKLYLQEDLRGKNVEKVKELAT
                     EKKVSISWTSKKSLSEITEGAVHQGFVLRVSEFAYSELDYILAKTRQEENPLLLILDG
                     LTDPHNLGSILRTADATNVSGVIIPKHRTVGVTPVVAKTATGAIEHVPIARVTNLSQT
                     LDKLKDEGFWTFGTDMNGTPCHKWNTKGKIALIIGNEGKGISSNIKKQVDEMITIPMN
                     GHVQSLNASVAAAILMYEVFRNRL"
     gene            complement(12208..13119)
                     /gene="trxB"
                     /locus_tag="ACL29Z_000786"
     CDS             complement(12208..13119)
                     /gene="trxB"
                     /locus_tag="ACL29Z_000786"
                     /EC_number="1.8.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001847397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004791 - thioredoxin-disulfide reductase
                     (NADPH) activity [Evidence IEA];
                     GO_function: GO:0071949 - FAD binding [Evidence IEA];
                     GO_process: GO:0019430 - removal of superoxide radicals
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin-disulfide reductase"
                     /protein_id="HGR0069123.1"
                     /translation="MYDTIIIGAGPAGMTAALYAARSNLKVALIEGGLPGGQMNNTSD
                     IENYPGYANISGPELAEKMFEPLENLGVEHIYGYVENVEDHGDFKKVMTDDQTYETRT
                     VIVATGSKHRPLGVPGEEELNSRGVSYCAVCDGAFFRDQDLLVVGGGDSAVEEALFLT
                     RFAKTVTIVHRRDQLRAQKVLQDRAFANEKISFIWDSVVREIKGENRVESVVFENVKT
                     GQVTEQAFGGVFIYVGLDPLSDFVKELNIQDQAGWIVTDNHMKTAVDGIFAVGDVRLK
                     DLRQVTTAVGDGAIAGQEAYKFITEHS"
     gene            complement(13185..13409)
                     /locus_tag="ACL29Z_000787"
     CDS             complement(13185..13409)
                     /locus_tag="ACL29Z_000787"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000924294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4059 family protein"
                     /protein_id="HGR0069124.1"
                     /translation="MLLQLFSLYFESLILTTILVLIFLGIWIGLRAMSGVDKTARARQ
                     AHLYDMIMIGVLVVPVLSFAVMSLILVFKA"
     gene            complement(13487..14230)
                     /locus_tag="ACL29Z_000788"
     CDS             complement(13487..14230)
                     /locus_tag="ACL29Z_000788"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397450.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HGR0069125.1"
                     /translation="MIKISNLSKSFSGQTVLDHLDLDIQKGEVVALIGSSGAGKSTFL
                     RSLNYLETPDSGSIQIDGFSVDFSKITQEEILALRRKLSMVFQQFNLFERRTALDNVK
                     EGLVVVKKLSDQEATKIAKEELAKVGLSDRENHYPRHLSGGQKQRVALARALAMKPDV
                     LLLDEPTSALDPELVGEVEKSIADAAKSGQTMILVSHDMSFVAQVADKILFLDKGKII
                     ESGTPDEIIHTPKEERTKEFFASYKRTYI"
     gene            complement(14230..15030)
                     /locus_tag="ACL29Z_000789"
     CDS             complement(14230..15030)
                     /locus_tag="ACL29Z_000789"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001103446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0006865 - amino acid transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HGR0069126.1"
                     /translation="MNVTTILASDWYQNLMQLIPDGKLFSLRSVFDGIPRIVQQLPTT
                     IMLTIGGALFGLVLALLFAIVKINRVKILYPLQAFFVSFLKGTPILVQLMLTYYGIPL
                     ALKALNQQWGTGLNINAIPAAAFAIVAFAFNEAAYASETIRAAILSVNPGEIEAARSL
                     GMTRAQVYRRVIIPNAAVVATPTLINSLIGLTKGTSLAFSAGVVEVFAQAQILGGADY
                     RYFERFISVALVYWVVNIGIESLGRFIERKMAISAPDTVQTDVKGDLR"
     gene            complement(15188..15544)
                     /locus_tag="ACL29Z_000790"
     CDS             complement(15188..15544)
                     /locus_tag="ACL29Z_000790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000889075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arsenate reductase family protein"
                     /protein_id="HGR0069127.1"
                     /translation="MLEFIEYPKCSTCKKAKQELNQLGVDYKAVHIVEETPSQEVILN
                     WLETSGFELKQFFNTSGIKYRELGLKDKVGSLSNQEAAELLASDGMLLKRPILVENGT
                     VKQIGYRKSYEELGLK"
     gene            complement(15538..16068)
                     /locus_tag="ACL29Z_000791"
     CDS             complement(15538..16068)
                     /locus_tag="ACL29Z_000791"
                     /EC_number="2.1.1.63"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003908 -
                     methylated-DNA-[protein]-cysteine S-methyltransferase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="methylated-DNA--[protein]-cysteine
                     S-methyltransferase"
                     /protein_id="HGR0069128.1"
                     /translation="MQKKYVKILYSSPIGILSLVADDHYLYGIWVQEQKHFERGLGDE
                     TIEEVVSHPILDPVIACLDDYFKGKPQDLSNLLLAPIGTNFEKRVWDYLQGIPYGQTV
                     TYGQIAQDLQVASAQAIGGAVGRNPWSILVPCHRVLGAGKRLTGYAAGVEKKAWLLEH
                     EGVDFKDRSNRRRSTC"
     gene            complement(16068..16562)
                     /locus_tag="ACL29Z_000792"
     CDS             complement(16068..16562)
                     /locus_tag="ACL29Z_000792"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000405845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetyltransferase family protein"
                     /protein_id="HGR0069129.1"
                     /translation="MEIRLAFPNEVDAIMQVMEDAKKCLADAGSDQWQNGYPNADVII
                     DDIISGQAYVALEEGELLAYAAVTKSPEEAYEAIYEGNWQAGESEYLVFHRIAVAADV
                     QGKGVAQTFLEGLIEGFDYLDFRSDTHAENKVMQHIFEKLGFKQVGKMPVDGERLAYQ
                     KLKK"
     gene            16697..17143
                     /locus_tag="ACL29Z_000793"
     CDS             16697..17143
                     /locus_tag="ACL29Z_000793"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000858725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1836 domain-containing protein"
                     /protein_id="HGR0069130.1"
                     /translation="MKTTFSYPKWAEIPNIDLYLDQVLLYVNQVCAPISPNKDKGLTA
                     SMVNNYVKNGYLTKPDKKKYQRQQIARLIAITTLKSVFSIQEIAQTLNTLQTQASSDQ
                     LYDAFVDYMNQGIDPANPIIQTSCQTVKLYHQTLDLIDHTQEEVIQ"
     gene            17140..17787
                     /locus_tag="ACL29Z_000794"
     CDS             17140..17787
                     /locus_tag="ACL29Z_000794"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001097995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hemolysin III family protein"
                     /protein_id="HGR0069131.1"
                     /translation="MNTSLKLSKQLSFGEEIANSVTHAVGAVIMLILLPISSIYSYEA
                     HGFLSSIGVSIFVISLFLMFLSSTIYHSMAYGSTHKYVLRIIDHSMIYVAIAGSYTPV
                     VLTLMNNWFGYLIIVIQWGTTIFGILYKIFAKKVNEKFSLALYLIMGWLVLAIIPAII
                     SQTTPVFWSLMVTGGLCYTVGAGFYAKKKPYFHMIWHLFILAASALQYIAIVYYM"
     gene            complement(17808..18389)
                     /gene="pdxT"
                     /locus_tag="ACL29Z_000795"
     CDS             complement(17808..18389)
                     /gene="pdxT"
                     /locus_tag="ACL29Z_000795"
                     /EC_number="3.5.1.2"
                     /EC_number="4.3.3.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000689933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004359 - glutaminase activity [Evidence
                     IEA];
                     GO_function: GO:0016884 - carbon-nitrogen ligase activity,
                     with glutamine as amido-N-donor [Evidence IEA];
                     GO_process: GO:0042823 - pyridoxal phosphate biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal 5'-phosphate synthase glutaminase
                     subunit PdxT"
                     /protein_id="HGR0069132.1"
                     /translation="MKIGILALQGAFAEHAKVLDQLGVESVELRNLDDFQQDQSDLSG
                     LILPGGESTTMGKLLRDQNMLLPIREAILSGLPVFGTCAGLILLAKEITSQKESHLGT
                     MDMVVERNAYGRQLGSFYTEAECKGVGKIPMIFIRGPIISSVGEGVEILATVNNQIVA
                     AQEKNMLVSSFHPELTDDVRLHQYFINMCKEKS"
     gene            complement(18390..19265)
                     /gene="pdxS"
                     /locus_tag="ACL29Z_000796"
     CDS             complement(18390..19265)
                     /gene="pdxS"
                     /locus_tag="ACL29Z_000796"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012054698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0042819 - vitamin B6 biosynthetic process
                     [Evidence IEA];
                     GO_process: GO:0042823 - pyridoxal phosphate biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal 5'-phosphate synthase lyase subunit
                     PdxS"
                     /protein_id="HGR0069133.1"
                     /translation="MTENRYELNKNLAQMLKGGVIMDVQNPEQARIAEAAGAAAVMAL
                     ERIPADIRAAGGVSRMSDPKMIKEIQEAVSIPVMAKVRIGHFVEAQILEAIEIDYIDE
                     SEVLSPADDRFHVDKKEFQVPFVCGAKDLGEALRRIAEGASMIRTKGEPGTGDIVQAV
                     RHMRMMNQEIRRIQNLREDELYVAAKDLQVPVELVQYVHEHGKLPVVNFAAGGVATPA
                     DAALMMQLGAEGVFVGSGIFKSGDPVKRASAIVKAVTNFRNPQILAQISEDLGEAMVG
                     INENEIQILMAERGK"
     gene            complement(19417..20796)
                     /gene="nox"
                     /locus_tag="ACL29Z_000797"
     CDS             complement(19417..20796)
                     /gene="nox"
                     /locus_tag="ACL29Z_000797"
                     /EC_number="1.6.3.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398482.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA];
                     GO_function: GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="H2O-forming NADH oxidase"
                     /protein_id="HGR0069134.1"
                     /translation="MSKIVVVGANHAGTACINTMLDNFGNENEIVVFDQNSNISFLGC
                     GMALWIGEQIDGAEGLFYSDKEKLEAKGAKVYMNSPVLSIDYDNKVVTAEVEGKEHKE
                     SYEKLIFATGSTPILPPIEGVEIVKGNREFKATLENVQFVKLYQNAEEVINKLSDKSQ
                     HLDRIAVVGGGYIGVELAEAFERLGKEVVLVDIVDTVLNGYYDKDFTQMMAKNLEDHN
                     IRLALGQTVKAIEGDGKVERLITDKESFDVDMVILAVGFRPNTALAGGKIELFRNGAF
                     LVDKKQETSIPDVYAVGDCATVYDNARKDTSYIALASNAVRTGIVGAYNACGHELEGI
                     GVQGSNGISIYGLHMVSTGLTLEKAKAAGYNATETGFNDLQKPEFMKHDNHEVAIKIV
                     FDKDSREILGAQMVSHDIAISMGIHMFSLAIQEHVTIDKLALTDLFFLPHFNKPYNYI
                     TMAALTAEK"
     gene            21090..22013
                     /locus_tag="ACL29Z_000798"
     CDS             21090..22013
                     /locus_tag="ACL29Z_000798"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000175414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0016740 - transferase activity [Evidence
                     IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0017013 - protein flavinylation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FAD:protein FMN transferase"
                     /protein_id="HGR0069135.1"
                     /translation="MTLRSHSERLMGTTITISLVDEQADIFLQKSFDLLKELEYRFNA
                     NSQESELMEINYQAGIAPVTVHPDLFELISLGLEHSLALSSHLNISIGPLIQTWRIGF
                     SDAKVAQPQEIESVLPLINPHGIELDSSTSTVFLKQKGMKIDLGCLAKGYSADKVAQF
                     LRKEGVTSALINLGGNILTIGKNQARGDNPWQIGIQDPANPRGNHLMTIPVVNKSVVT
                     SGIYERHLTVDGQDYHHIFDSQTGYPVETELASLTIISDKSVDGEIWTTRLFGERPAS
                     ILWQVESLEGIEVILIDKEGHLSCSSGIPTL"
     gene            22073..22678
                     /locus_tag="ACL29Z_000799"
     CDS             22073..22678
                     /locus_tag="ACL29Z_000799"
                     /EC_number="1.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006153967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008752 - FMN reductase (NAD(P)H) activity
                     [Evidence IEA];
                     GO_function: GO:0010181 - FMN binding [Evidence IEA];
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA];
                     GO_function: GO:0052873 - FMN reductase (NADPH) activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NADPH-dependent FMN reductase"
                     /protein_id="HGR0069136.1"
                     /translation="MLKLIAIVGTNSKRSTNRQLLQYMQKHFTDKAEIELVEIKAIPV
                     FNKPADKQVPAEILEIAAKIEEADGVIIGTPEYDHSIPAVLMSALAWLSYGIYPLLNK
                     PIMITGASYGTLGSSRAQLQLRQILNAPEIKANVLPDEFLLSHSLQAFNPSGDLVDLD
                     VIKKLDAIFDDFRIFVKITEKLRNAQELLRKDAEDFDWENL"
     gene            22697..23941
                     /locus_tag="ACL29Z_000800"
     CDS             22697..23941
                     /locus_tag="ACL29Z_000800"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000673688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase"
                     /protein_id="HGR0069137.1"
                     /translation="MKFVGLVGSNYDQSYNRKLLEFIRRYFKLKFELEVLEIDEVPMF
                     NQDEKWDESFQLRYLYNKITRADGVIIATPEHNHTISASLKSVLEWLSYEVHPFENKP
                     VMIVGASYYDQGTSRAQVHLRKILDAPGVNAYTLPGNEFLLGKAKEAFDNNGNITNEG
                     TVKFLETCLDNFVKYVGVVSKLKKPKPIESEDLDCGKPIATTITEVDPDDPEWVEKVA
                     AFTGAVSGDTYVKLDHGILTVNQIDMFLKAMPFELTYADDNNQFLYYNNAHQDPDTMF
                     AKRVPPQSGSRMSTVHGSLPPARMKNVEWVIGTLRNGNQEYVRTIVPGSPAGVINTHN
                     YQAMYYPDGSYAGINEIVFNFQPWLDWYLKETGQRLVGGSGPFAPAAGGHGDADATSG
                     ASDSGDAGGHGGDADATAGASY"
     gene            complement(24164..24421)
                     /locus_tag="ACL29Z_000801"
     CDS             complement(24164..24421)
                     /locus_tag="ACL29Z_000801"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002901318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF896 family protein"
                     /protein_id="HGR0069138.1"
                     /translation="MDPKKIARINELAKKKKTEGLTPEEKVEQAKLREEYIEGYRRAV
                     RHHIEGIKIVDEEGNDVTPEKLRQVQREKGLHGRSLDDPNS"
     gene            complement(24463..26499)
                     /gene="glyS"
                     /locus_tag="ACL29Z_000802"
     CDS             complement(24463..26499)
                     /gene="glyS"
                     /locus_tag="ACL29Z_000802"
                     /EC_number="6.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012000066.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004820 - glycine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006426 - glycyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycine--tRNA ligase subunit beta"
                     /protein_id="HGR0069139.1"
                     /translation="MTKNLLVELGLEELPAYVVTPSEKQLGEKMAAFLKGKRLSFEAI
                     QTFSTPRRLAVRVTGLADKQSDLTEDFKGPAKKIALDSDGNFTKAAQGFVRGKGLTVE
                     DIEFREIKGEEYVYVTKEEIGQAVEAIVPGIVDVLKSLTFPVSMHWAGNSFEYIRPVH
                     TLTVLLDEQEFDLDFLDIKGSRVSRGHRFLGQETKIQSALSYEEDLRKQFVIADPCER
                     EQMIVDQIKEIEAKHGVRIEIDADLLNEVLNLVEYPTAFMGSFDAKYLEVPEEVLVTS
                     MKEHQRYFVVRDQDGKLLPNFISVRNGNEERLKNVIKGNEKVLVARLEDGEFFWREDQ
                     KLVISDLVEKLNNVTFHEKIGSLREHMIRTGQITVLLAEKASLSVDETVDLARAAAIY
                     KFDLLTGMVGEFDELQGIMGEKYTLLAGETPAVAAAIREHYMPTSAEGELPESKVGAV
                     LAIADKLDTILSFFSVGLIPSGSNDPYALRRATQGVVRILDAFGWHIAMDELIDSLYA
                     LKFDSLTYENKAEVMDFIKARVDKMMGSTPKDIKEAVLAGSNFVVADMLEAASALVEV
                     SKEEDFKPSVESLSRAFNLAEKAEGVATVDSALFENDQEKALAEAVETLILSGPASQQ
                     LKQLFALSPVIDAFFENTMVMAEDQAVRQNRLAILSQLTKKAAKFACFNQINTK"
     gene            complement(26711..27628)
                     /gene="glyQ"
                     /locus_tag="ACL29Z_000803"
     CDS             complement(26711..27628)
                     /gene="glyQ"
                     /locus_tag="ACL29Z_000803"
                     /EC_number="6.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018163989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004820 - glycine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006426 - glycyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycine--tRNA ligase subunit alpha"
                     /protein_id="HGR0069140.1"
                     /translation="MSKKLTFQEIILTLQQFWNDQDCMLMQAYDNEKGAGTMSPYTFL
                     RAIGPEPWNAAYVEPSRRPADGRYGENPNRLYQHHQFQVVMKPSPSNIQELYLESLEK
                     LGINPLEHDIRFVEDNWENPSTGSAGLGWEVWLDGMEITQFTYFQQVGGLATGPVTAE
                     VTYGLERLASYIQEVDSVYDIEWADGVKYGEIFIQPEYEHSKYSFEISDQEMLLENFD
                     KFEKEAGRALEEGLVHPAYDYVLKCSHTFNLLDARGAVSVTERAGYIARIRNLARVVA
                     KTFVAERKRLGYPLLDEETRAKLLAEDAE"
     gene            complement(27999..28759)
                     /locus_tag="ACL29Z_000804"
                     /pseudo
     CDS             complement(27999..28759)
                     /locus_tag="ACL29Z_000804"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397459.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Tu"
     gene            complement(29032..29874)
                     /locus_tag="ACL29Z_000805"
     CDS             complement(29032..29874)
                     /locus_tag="ACL29Z_000805"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397460.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase"
                     /protein_id="HGR0069141.1"
                     /translation="MNTYQLNNGVEIPVLGFGTFKAKDGEEAYRAVLEALKAGYRHID
                     TAAIYQNEESVGQAIKDSGVPREEMFVTTKLWNSQQTYEQTRQALEKSIEKLGLDYLD
                     LYLIHWPNPKPLRENDAWKTRNAEVWRAMEDLYQEGKIRAIGVSNFLPHHLDALLETA
                     TIVPAVNQVRLAPGVYQDQVVAYCREKGILLEAWGPFGQGELFDSKQVQEIAANHGKS
                     VAQIALAWSLAEGFLPLPKSVTTSRIQANLDCFGIELSHEERETLKTIAVQSGAPRVD
                     DVDF"
     gene            complement(29988..31379)
                     /gene="pgdA"
                     /locus_tag="ACL29Z_000806"
     CDS             complement(29988..31379)
                     /gene="pgdA"
                     /locus_tag="ACL29Z_000806"
                     /EC_number="3.5.1.104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013193417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0050119 - N-acetylglucosamine deacetylase
                     activity [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA];
                     GO_process: GO:0042545 - cell wall modification [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan-N-acetylglucosamine deacetylase
                     PgdA"
                     /protein_id="HGR0069142.1"
                     /translation="MNKSRLGRGRHGKTRHVLLALIGILAISICLLGGFIAFKIYQQK
                     SFEQKIESLKKEKDDQLSEGNQKEHFRQGQAEVIAYYPLQGEKVISSVRELINQDVKD
                     KLESKDNLVFYYTEQEESGLKGVVNRNVTKQIYDLVAFKIEETEKTSLGKVHLTEDGQ
                     PFTLDQLFSDASKAKEQLIKELTSFIEDKKIEQDQSEQIVKNFSDQDLSAWNFDYKDS
                     QIILYPSPVVENLEEIALPVSAFFDVIQSSYLLEKDAALYQSYFDKKHQKVVALTFDD
                     GPNPATTPQVLETLAKYDIKATFFVLGKNVSGNEDLVKRIKSEGHVVGNHSWSHPILS
                     QLSLDEAKKQITDTEDVLTKVLGSSSKLMRPPYGAITDDIRNSLDLSFIMWDVDSLDW
                     KSKNEASILTEIQHQVANGSIVLMHDIHSPTVNALPRVIEYLKNQGYTFVTIPEMLNT
                     RLKAHELYYSRDE"
     gene            complement(31617..31985)
                     /locus_tag="ACL29Z_000807"
                     /pseudo
     CDS             complement(31617..31985)
                     /locus_tag="ACL29Z_000807"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000603324.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus and C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="PD-(D/E)XK nuclease family transposase"
     gene            32206..33183
                     /locus_tag="ACL29Z_000808"
     CDS             32206..33183
                     /locus_tag="ACL29Z_000808"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002206301.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HGR0069143.1"
                     /translation="MLKLGVIGTGAISHHFIEAAHTSGEYQLVAIYSRKLETAATFAS
                     RYQNIQLFDQLEVFFKSSFDLVYIASPNSLHFAQAKAALSAGKHVILEKPAVSQPQEW
                     FDLIQTAEKNNCFIFEAARNYHEKAFTTIKNFLADKQVLGADFNYAKYSSKMPDLLAG
                     QTPNVFSDRFAGGALMDLGIYPLYAAVRLFGKANDATYHAQQLDNSIDLNGDGILFYP
                     DYQVHIKAGKNITSNLPCEIYTTDGTLTLNTIEHIRSAIFTDHQGNQVQLPIQQAPHT
                     MTEEVAAFAHMIQQPDLNLYQTWLYDAGSVHELLYTMRQTAGIRFEAEK"
     gene            33180..34262
                     /locus_tag="ACL29Z_000809"
     CDS             33180..34262
                     /locus_tag="ACL29Z_000809"
                     /EC_number="3.6.4.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007521532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004386 - helicase activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HGR0069144.1"
                     /translation="MKTKLPTEWQELSDQLGFQEFTPIQTQLFEPLLAGENLLGVSQT
                     GTGKTLAYLLPSLLRLQKKKAQQLLILAPNTELAGQIFDVCKTWAEAIGLTAQLFLSG
                     SSQKRQIERLKKGPEILIGTPGRIFELIKLKKIKMMNVETIILDEFDQLLDDSQIHFV
                     EKITHYAPRDHQLVYMSATTKFDQEKIVPNTRTINLSDQKLDNIQHFYMQVDQRHRVD
                     MLRKLAHVEDFRGLVFFNSLSDLGNAEEKLQYRDILTVSLASDVNVKFRKIILEKFKD
                     NQLTLLLATDLLARGIDIDSLECVVNFDIPRDSETYTHRAGRTGRMGKEGYVITLVTH
                     PEEIKKLKKFASIREIVLKNQELYIK"
     gene            complement(34326..35176)
                     /locus_tag="ACL29Z_000810"
                     /pseudo
     CDS             complement(34326..35176)
                     /locus_tag="ACL29Z_000810"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611577.1"
                     /note="frameshifted; incomplete; missing N-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS630 family transposase"
BASE COUNT        10400 a         7851 c         6350 g        10575 t
ORIGIN      
        1 tgcacttttc ttgtacaact ttagtccacg gtaaataggc ctctaaaacc tctttgttta
       61 cgagagtttc ctcgtttgga agacattcta gaagatagga tagatatttc tcactattta
      121 gttgatgacg tttagctgtt tccaataagc tcataataat agctcttgct ttagctcctt
      181 caaaaacttt gagaaaacaa ccaccctcgc ttttttaaac tgagcttagg ctaaaagagt
      241 ccagtggact cttttactcc gtcccataac caatgattta atggcgcgtt cagctagatt
      301 attggaaagg accagatgtc cgtcttttaa aatggtctta aaggtttctt catacttgag
      361 gctgtattca attgcccttc ctagttttga acccgataaa actgactgac gacggcacca
      421 agcaaagaag tcttccagta ggggttggag atgttcttga cgtttctgta gtcgttcatc
      481 agctggcaaa gcctcccagt ctctttccaa ggaaaataac tgatcacaat aagctaaacc
      541 tttagctcct aaggatgatt tatctgcttg cttggggggc acttcaaaaa acttccttct
      601 cacatgcgcc caacatccaa caagtgcagc ttcttccagt tgacgataag cttctagctg
      661 ttcgcagttt accaagctta gcgtcgcctt gctcctaaac cttggactgc tatcgcatag
      721 gcagaactag aggactaaag tcctaagtta ctgccgcaac atatcacaat gcacatagcc
      781 agaataatct cctaggaatt ctggcactac cgaaccactc cgacgctgat catggtggta
      841 cagcgtaatc ccttgtttct ctgatttacc tgacaaaaaa gtacaatagt aagtcagctg
      901 actatcactt tctaagaccc gataagaggt ttcatctgca tgaagaagag cttgttctaa
      961 caacttttct cgtaaaaggt tataaaggga ctctaaatag tattgactcg ccttgatatg
     1021 ccaattagca atttccttac gtgtgattgg taaacctatc ttagcccaat cttcttcttg
     1081 gcgataatta ggtaccttta gattaaactt ctgatggatg gtgtgagcga taatagaagc
     1141 tgagccaagg ctatacgcca aaggggcttt aggaatagga gctttcacaa ttttatcact
     1201 cggattttta tcactgcatg cttggcattt gtaagcgtgt tggatatgat ctatgcgttt
     1261 taattgcgca ggaataaaga ctaattcttg tcgttgaagg gttgctccaa tctcttttag
     1321 atctccctga caatcagagc aaatgctctc ttctacttga tgatgaactt cttctgaatc
     1381 aaattgggca agaagagctt ggcgtttccc tttagatttc ttacgtttgt aggtaatttc
     1441 ctctgtttca actgggaaca tctccatctt tctcagatgg agactcttcc tcaaaaaggt
     1501 tgagttgtcc aaaagggcaa acacttttct cagaggattt tccagagagc ttttgcgtta
     1561 gataagccac ttgttcacac agaagggaaa gttcattagt gagactatca attatagcac
     1621 tctgttgttg aatgattttc aatcttctcc catagacttt cctccttatt tcctaacttc
     1681 tattatatag tgtattgaat ctataacagt acaccttgac tgctaaaata tttctataaa
     1741 ttaatttgac tttcctgata gagatgttca tatcttattt caattcacta tactaaaaag
     1801 aaagtcctca tttcaataga aatcacgact ttctgataaa tttattttgg gagtgataga
     1861 aaagcccttc ataagccaat ctacttgttc aggtgtgaga gctttgacat ccttttctgt
     1921 actgggccaa gtcagtctgc cgttctcaaa gcgtttatat agtagccaaa atccttgacc
     1981 atcccagtaa agggctttaa agcggtcttt acgtccacca caaaagagaa aaacttgacc
     2041 ggagaaagga tccaattcaa agtgggtttt aaccagataa gccagtgaat cgattccttg
     2101 tctcatatca gtcttcccac acacgagata gacctgccct aggctagata gatgaattgt
     2161 catagagcaa caccttatcc aaaagctgtt ctaccatttc gagattgaga gattgaaaaa
     2221 aacttagttc aagcttgcca atacgaattt taagcagaat atcatttctc tttttagaat
     2281 caaaaggacg agattgtgga atctctacag gaacaatagg ttgtggcatt aaaatatcct
     2341 ccaatagttt tactttacta atagtataca ggaggagctc catgaatgat agataccttg
     2401 ttatgacgcg cttaccatat tagaaagttg gctctctaat taaattaatt ctcattatat
     2461 atatcaaaag accgcagttt gaaaactacg gtctaatttt ttgtccaaat gtaaaccact
     2521 tggaactatt attcaattta ttctttttag caaatgttcc cgttttaatc ccagttacag
     2581 tttttaatcc tctgtaaccg ttgattttac aaagctttta atttttttgc gattattccc
     2641 actcaactgt tgcaggtggt ttacttgtaa tatcgtagac gatacggtta acatgatcca
     2701 cttcatttac gatacgtact gagatttttt gaagtacttc ccatggaatt ttggcaaaat
     2761 cagcagtcat accatcgata gaagtgatag cacggattgc aatcgtgtag tcatacgtac
     2821 gaccgtcacc cataacaccg actgaacgaa cgcctgtgtt aacagtgaag tattgccaaa
     2881 tatcgcggtc aagtccagct ttagcgattt cttcacgaag aatagcgtct gattcacgaa
     2941 cggtttcaag tttctcttca gtgatttcac ccatgacacg gatagcaagt cctggtcctg
     3001 ggaatggttg gcgccatacg atatggtctg gcataccaag ctctgtacca agagcacgaa
     3061 cttcatcctt gtaaagagta ttgagtggtt caatcaattc aaactgcata tcttctggaa
     3121 gaccacccac gttgtggtgt gacttgatag tttgagctgt atccgtacca gactcgataa
     3181 catctgtata taaagtacct tgagcaagga atttcacatc tttgagcttg cttgcttcgt
     3241 catcgaatac atagacaaac tcgttaccga tgattttacg tttttgttca ggatcagaaa
     3301 cgccagcaag tttgtcaagg aaacgtttag cagcgtctgc tttgacgata ttcaaaccaa
     3361 acttaccacc gagcatgtcc ataacttgat cagcttcgcc tttacgaaga agaccgtggt
     3421 ctacgaagat acagatcaat tgatcgccaa tcgctttttg gagaagaact ccaacgacag
     3481 atgagtcaac accacctgat agaccaagaa ggacacgttt atcaccgacg gtttcacgaa
     3541 tttttttgat ctgcatgtca atgaaattat ccattgacca gtcaccttta gccttacaaa
     3601 tgttaagggc aaagttacga aggatatcat ttccgtatac agaatgacga acttctgggt
     3661 ggaattggat accgtaaatg tgtttatctg ggttttcgat ggctgcgtat gggcagtcag
     3721 ctgatgtacc tgtacgaaca aagtcagcag gaatctcagt aaccgcatca ccatggctca
     3781 tcaaaacagt ctgttcatca ggtgttgatt caaaaagcgc tgatggtgtg tgagttaggg
     3841 ttgattgacc gtattcacga tttccagcat cacctgcagg aacaactttt cctccaagtt
     3901 tatgggtcaa taactgcata ccataacaga ttcccaaaat tggaattccg agttcgaaga
     3961 tttctgggtc aatatcaaat gaaccatctt catatacaga atttggacca cctgatagaa
     4021 taattcctac aggattgact tcacgaactt cagcagctga aattttatgg ctttttagtt
     4081 ctgaaaaaac accaatctca cggatacggc gtgaaatcag ctggttgtac tggctaccat
     4141 agtccaatac gatgattttt tctatatctt gcaaatcagt tgaaatgttg ctcatctttt
     4201 tcctttctca aaagaaatat cttttcccaa tattctatca caaataaggg cgaattacca
     4261 actaaacaag gcgaagtttg actttttcta gtttattggg gtacaataga gaaaagatag
     4321 aaatgaagtg aaaaatatgc tacctgctta tatgaaaatc catgatcaga taaaaaagaa
     4381 tattgacgag caccgttggg ctattggtga gaggcttcct agtgaaagag atctagctga
     4441 gcagtttgcg gtcagtcgca tgaccctccg ccaagccgta tctctattag tcgaagaagg
     4501 cgtcttagag cgccgtgtag gaagcggcac ctttgtttcc agtactcgag tacaagaaaa
     4561 gatgcgaggg acaaccagtt ttactgaaat tgtcaaatcc cagggtaaag ttccctctag
     4621 ccagctcatt tcctacaaaa aaaccattcc caatgagcaa gaagttacca agctaggaat
     4681 ttttccaacg gacaatatta tccgaatgga gcgggtccgc tatgccgacc aagttcccct
     4741 agtttatgaa gttgcttcta ttcctgaaaa attcattaag gactttaaaa aagaagaaat
     4801 caccagtcat ttcttccaaa ccttgcaaaa acatggctat cgtatcggca aatctcaaca
     4861 gaccatctat gctcgccttg ctaaagaaaa gattgcccac tatttggaag ttgaaaaagg
     4921 acatgctatt cttggattga cccaggtttc ctacctagaa gatggtactg cttttgaata
     4981 cgtaaaaagt caatatgtag gcgaacgctt tgaattttat cttgaaaata attagattac
     5041 cacgcaaaaa ctctctgtca cggacaaaga gtctttttta tttttctaag aataaatctt
     5101 tcaaagaaat caaagttaca gcaaacaata tcattgccat accaagaaaa tcaatgggat
     5161 aaaattgttc attcattatt aagaaggcaa agaaaatcgc cgatattggc tcaattgaag
     5221 ccaacaagct tgacttgacc ggtcctatca gactggctcc tttaaggaaa gctgtatagg
     5281 caaagacagt cccgataagg ataatgcctg caaacgcaag gagaaaatca agactagtcg
     5341 ggatatcggc ctgtagaacc cctgtaaaag gaagggcgac caaacctgct atgaccattc
     5401 ccacaccaat gaccaagctg ctcccccact ttttaatcaa ggctatgggt aaaatgatat
     5461 acagagcata agtcaaggca gaaaagagac cccagaacag gccaacaggt gtcatggata
     5521 actggtccaa ctgcccatgt gttgcgatca ggaaggttcc tccgatggcc aatatgatgg
     5581 aaactatctc tcccagtgtc ggtgccaccc tatccttgat acagctataa attaaaattc
     5641 cgacaggaca aacatactga agcaccgtcg ctgttcccgc attggtctcc tgaatagcag
     5701 acagataggc aaattggttg agaaaaagac caatcagagc aaaaataaga agagacagca
     5761 aactctttct atcctttaaa aagaccagta ttttatcctt tgtagtagca taagtcaaga
     5821 gcatgagaat tccaccagcg attaaaagac gcaagttggt caagaccaga gccgaaattc
     5881 cgtgtgccat taggtattgg ccactcgttc ctgacaaccc ccaagcaata ccagccacaa
     5941 ctgttagtaa agtccctttt aaactatttg acatgtctct ccttactctt ctttgcgaat
     6001 caagttcatc acttgattgc ggtctaatat ccattgagct ctctcgtcct tttcataggt
     6061 acgattcgat aggaaaatag tggcttcttg cttctgacga ttccacatga taaaggtacc
     6121 tgtatagccc gtatggtcta gccaatctcc ttccaaattc catgctaaag aacgttcctt
     6181 gtcatccaaa ggagaaaaat tttgatttaa gtctcttgca aaatcatctg ctaaatagtg
     6241 ttctaaaaag atttgtaaat cctttatagt cgaaaataaa ccagcactcc cagcatgtct
     6301 acccaggaga cgagccttgg gatcatgcac tatgcctgcc tctacacctc taactgttgg
     6361 aacagcaagc tcaactggcc caaacttagt ttccgtcatt ccccaaggtt tccagacttg
     6421 atcctttaaa atcacatcca aatcttgatt aaaaattctt tccaaaataa agcccaacag
     6481 caaaaaatgg acatccgaat aaagaaaggc tggctgactt cgtctgttga gatgaaacat
     6541 cgcttccttt aattcagggg ctgttaaaag atcacgatta ggaataaaag gatcaaggtc
     6601 tgttgcatga gtcaagagct ggcgaatagt gatgtctgga taatcactct caggtaaaaa
     6661 atctattacc agtctatcaa tatctaattg acctatttcc cacaagaagg tacaaactgt
     6721 gccaacccca acaaccttgc tgacactagc taggtcataa actagtcctg cctcagtctg
     6781 caagccatgc tctggggcac tctggcctaa atagaactct gtccattgat tgtccttaaa
     6841 atacgcaaaa gaggctccgg gataaattcc tgcctcgatt tgttcttcta tttttttaat
     6901 aatcttggtc cacttcatac ttcttcaaac cacaattcaa cattatttct atctttacca
     6961 aggaagaatt tttcagactt aggaataaaa tattcagtag actcaaactt ctggcgaaga
     7021 cttgctatgt ctaattcatt gaccaagaac ttgagcatag ataagtccca ggtaaccgta
     7081 ttgtccacag tcaaatcctg cccctgagct ggaataaaat caagggatgc cccaatttca
     7141 gatgattcca agaaactttc gatatcagtt gggagatgta attccataga aatctcaaat
     7201 ttacttaaag aaattgatgc caaatctgtt tgaaattcag gcttttctcc tacttctact
     7261 agacttgctc tgtcatcttc cgcatgaatc aaaatcaaat catcttctgg tgagaaaatt
     7321 tcaaaagcgt agccattttg acctttatat aatcgatgaa tcgaatctgt tttagataag
     7381 attccttcaa tttctaaggg attttccacc ttgacaatca atctagctag tttttttctt
     7441 ccctctacct tacgagtacg catactggga gcttcttcta aaaccagctt ttcaagaccc
     7501 gtttggtcac ctagtgacag aaaggccgat tcttctaaca gggccttcat tccaagggtt
     7561 tcaatataaa atgtttcatt taattttcta ttattagctt ttaaagtagg aataatccgt
     7621 acaatctgat ttacattcat aaattcctcc gtcacttttt attttaaagg attttagaat
     7681 tttttacaag atattatgct caaatttaac attatttagc tatttagtaa agatagtctt
     7741 tcaaggcttt tgacaaagcc tgataaccag caatactgag gtgcagtcca tcagttgtat
     7801 attctttttt gagttggcct gcttggtctg tcaaacaatc aaatactggc acaaattcca
     7861 cctgcatata ggcagatgca agctcttgat aggcttgatt ccaattctga attttttcat
     7921 tcgagcggat atagactgcc tgctggtact tctctccctc attgacaggc aaaatggaaa
     7981 gcaatttaat ctctgtcaat ggataatcgc gagcaacgga ttgaatgata gcttcgagac
     8041 tattgagagc ctcattcaca ggaacatcct ttccgatatc atttgtccca atcagaagaa
     8101 aaattttatc tactgctcca ccatatagat gagcatcaag gttctctagt aacagtcctg
     8161 tctgatagcc acgaattcct cgattgacaa tcgtctttga agtcccaaat agctcctgta
     8221 gaggataata ctcgacaatg gaatccccaa taaaaagaat gtttggttct acaacagaaa
     8281 tgtgatttag gtgacgatat ttggtttgaa ttttttcttg ttcctttagg agccaatttt
     8341 ctaataactg tactgccact tcattctcct ttttctaacc agttttccaa gacttgataa
     8401 actcctcctt ggctgttggc tggtgctaga gcagtcgcca cagctttggc tttctcatca
     8461 gcattttcca tcgcataggc aattccagcc atttcaagca tttcaacatc attttcacta
     8521 tcaccaaaag ccatgatttc ttgggatttc aagtcccagc gcttgagtaa ttcctccaag
     8581 ccccatgctt tatgaatccc agcttggagg atatcaatgc aaccatagcc actggataca
     8641 gctcggacac ggccatcaaa gagagcattg atttcttcca aaaccgaact caaacgttcc
     8701 tcaccaacaa ccatgctcat cttgagcaca ccaccaaaga ggtcagatgt taattcatcc
     8761 acaaattgca tccgttggta gaatttttca atcatttctg gagtcataaa actttcaaga
     8821 tctgtaaaaa tcgtaccttc cttgacaaaa tcacccttca tccccgttac aacaaactgg
     8881 tcctgacacg ctcgaccctt gaaatgagcc aaagccttgt tgacaatggc gtcatcccat
     8941 gtctgagcct gaatcaattc attgttttca aaaatacgag cgccattagc aacaaccaga
     9001 accactcgat ccaccaaggg actcagtagt tgtctcatgc ggtgaatttc attgcccgtc
     9061 gcaatgacaa aacgaatgcc cctttgatcc aactgatcta aaatcttttc caatcgtggg
     9121 agatcaagct gacctctagc atccagcaag gtcccatcca tatctgtcgc aattacctta
     9181 atcatcattt actttcctct ggattcaagc taataccact tcaatcccac atgttcattc
     9241 atttctttat aggctgtatc aattcgttcc ttagtcgctt catctaactg gtcacgatga
     9301 ctgccatcct ctataaaatc ttccaaaata taagtttggt aatgatacaa gggatatcct
     9361 tctggtgaaa aggttccctt tggtgttcga ttgacccaag taggatgagc tttagctgtt
     9421 ccgatagttg tttttccatc cttcttcttg atggtgacat ccatgagaac accacgttca
     9481 gtccacttag cattctcttc atctcccata gattcaatcc gttgattgga aatgaagttc
     9541 cccatttaat agataatgag tttcttatct ccatcttttt caaccgtttc agatggttca
     9601 acaacgtgag gatgccctcc aaagataata tccgctcccc aatcgatcat cttgtgataa
     9661 agagcttttt gttcttcagt tggttccaat cgatactcaa cacccatctg aagcatgata
     9721 atggtgatat ttgcttcctt ctctgcccgt tcaatttcaa ccttcatctt atcttcgttt
     9781 aaatctgaaa gataacgatt atagtcttcc tgagaaatat actgctcaat tccattgaaa
     9841 tcataggaat aggctaacaa tgcaaccttg ataccattca cttccttaat gaccagcgga
     9901 gcctgatcac gtggttcgtg cgtataaact ccgattggag tgattccagc tttctcaata
     9961 atatcggccg ttgaaataac tccctcaatt tgcgaatcca aaatatgatt atgagctaaa
    10021 tccagcacat gataacctgc ctccttaata gcatccataa cttcagcagg agcattaaag
    10081 agaggataac ccgctaaata atgatcctta ttaatggttt cttcaaaatc accaatagct
    10141 aaatctgctt gcttgaacca aggagtcaca tactcaaaat tttcatgaaa gtcataggta
    10201 ccgtcttctt ttttagctga aaagaaaagt ccatcgtggt agagcaaatc cccgtgggcc
    10261 ataattctgg cagttttttc ctcttcctac tcctgagact tttgcttagt cccctcttga
    10321 gaaatagtat ctcatttttg actagtcaaa ggattccttg gaagctttca aacaacaaga
    10381 ccaagcccat tgataaacca actgctagca agagtatcgc cacaaatccc ttattgctcc
    10441 acttgcgata actcctaaaa agtttaccaa gcccttcata aaacgaaaag ctaaaccacc
    10501 ctgatttcga ttttgtcttc tttgtatctt cgttctccct actttcttat gcaagccttt
    10561 tctttttatt atatcacaga taagtatttc tttcacaatt gaattgaact tcctatctat
    10621 tttctataaa tcctaaatgc cataatgctt tcaattcttg tcattttgtg atatcatgta
    10681 gaggtaatga aaggaaatga actaatccac agtggcttat tccaagtata ccacttgggc
    10741 tttggcagta gctaactgca ctaaacataa tataaggaga gaaaatgtct gcaatagaac
    10801 gtattacaaa agctgctcac ttaattgata tgaacgatat tatccgtgaa gggaatccta
    10861 ctctacgcgc gattgctgag gaagtcactt tccccctatc tgaccaggaa atcatcctag
    10921 gcgaaaagat gatgcaattc cttaaacatt cccaagatcc tgtcatggct gaaaaaatgg
    10981 gactccgcgg tggtgttgga ctggctgctc cccagttaga tatctcaaaa cgcattatcg
    11041 ctgttttggt acctaatatt gttgaagaag gcgaaactcc acaggaagcc tacgatttgg
    11101 aagccattat gtacaatcca aaaatcgtct ctcactctgt tcaagatgct gctcttggcg
    11161 aaggagaagg ttgcctgtct gttgaccgta acgtgcctgg ctatgttgtt cgccatgccc
    11221 gcgttactgt tgactacttt gacaaagatg gagaaaaaca ccgtatcaaa ctcaaaggct
    11281 acaactccat tgttgttcag catgaaattg accacattaa cggtatcatg ttttacgatc
    11341 gcatcaatga aaaagaccca tttgcagtta aagatggttt actgattctt gaataaagaa
    11401 aatcccgttg caagacgggg ttttgtgtta taatagaggc atgaaaacaa atgatattgt
    11461 ctatggtgtc cacgccgtta ccgaagccct ccttgcaaat acaggaaaca aactctacct
    11521 ccaagaagat ctccgaggta agaatgttga gaaagtcaag gaactagcta cagaaaagaa
    11581 agtgtccatt tcttggacat caaaaaaatc tctctctgag attactgaag gtgctgttca
    11641 tcaaggtttt gttctacgag tgtctgaatt tgcctatagc gagctagatt acatccttgc
    11701 aaaaacacgc caagaagaaa atccacttct attgattcta gatggtctaa ccgatcccca
    11761 taatctgggt tctatcttgc gaacagccga tgcgaccaat gtttcaggtg tcatcattcc
    11821 caagcaccgt actgtcggag taactcctgt cgttgccaaa acagccacag gtgctattga
    11881 acacgttcca attgcccgag tgaccaacct cagtcaaacc ttagataaac ttaaggatga
    11941 aggtttctgg acctttggaa cggatatgaa cggtactcct tgccacaagt ggaatacaaa
    12001 agggaaaatc gccctcatca ttggaaatga aggaaaaggt atctctagca acatcaaaaa
    12061 acaggtcgat gaaatgatta ccattccgat gaatggacat gttcaaagcc ttaatgccag
    12121 tgttgctgcg gccattctca tgtacgaagt tttccgaaat agactataaa aaagtttcca
    12181 gtcatctgat tggaaacttt tttatgatta actatgttct gtaatgaatt tataggcttc
    12241 ttgaccagcg atagctccat ctccaaccgc tgttgttact tggcgaaggt ctttcaagcg
    12301 aacatctcca actgcaaaga taccgtcgac tgcagttttc atgtggttat ctgtcacaat
    12361 ccatcctgcc tgatcttgga tattcaattc tttaacaaaa tcgctaagag ggtccaaacc
    12421 aacatagata aagacaccac cgaaggcttg ttctgtcact tgacctgttt tcacattttc
    12481 aaatacgact gattctactc ggttttcacc cttgatttcc cttactacag aatcccagat
    12541 aaagctgatt ttttcattcg caaaggcgcg atcttgtaaa accttttggg cacgaagttg
    12601 gtcacgacgg tgaacaatgg taacagtctt agcaaaacga gtcaagaaga gggcttcttc
    12661 aacagctgaa tctccaccac caactaccaa taaatcttgg tcacggaaga aagcaccatc
    12721 acacacagca cagtaagaaa caccacgact gttcagttct tcttctccag gcactcccaa
    12781 aggacggtgt ttagaaccag ttgctacgat aactgtacgt gtttcatatg tttggtcatc
    12841 agtcatcact ttcttaaaat caccatggtc ttcgacattt tcaacataac cataaatgtg
    12901 ctcaacacca agattttcaa gtggttcaaa catcttttca gccaattcag gtccactaat
    12961 attagcgtat cctgggtaat tttcgatatc agatgtatta ttcatctgac cacctggcag
    13021 accaccttca atcaaagcta cttttagatt gcttcgagca gcatacaagg ccgcagtcat
    13081 ccctgcaggt ccagcaccga taataatagt atcgtacata tagattcctt ctttcttgtt
    13141 gtaactatct ttattctaac tctttcttgt caatcacgca aggattatgc cttgaaaaca
    13201 agaattaaac tcataaccgc aaaggataat actgggacaa ccaagactcc aatcataatc
    13261 atatcataga gatgggcttg gcgagccctg gctgtcttat caactcccga catggctctc
    13321 agaccaatcc aaatccctaa aaaaatcaga acaaggatgg tggtcaagat caaactctcg
    13381 aaatataaag aaaatagttg cagtagcatg atttctctca tttctatctt ttttaaagag
    13441 taaactcagc tagtccaact aactgagttt tcctttatct attatatcaa atataagtcc
    13501 gtttgtaact agcgaagaat tcttttgtcc gctcttcttt aggggtgtgg ataatctcat
    13561 ccggagttcc agactcgatg attttcccct tatctaagaa gagaatttta tccgcaactt
    13621 gggctacaaa ggacatgtca tgactgacca aaatcatggt ctgacctgac ttagcagcat
    13681 ctgcaataga cttttctact tcaccgacca attctgggtc aagggctgaa gttggttcgt
    13741 ctaagagcaa aacatctggt ttcatagcaa gcgcacgcgc tagggcaacc cgttgcttct
    13801 gtccacctga taaatggcga ggataatggt tttcacggtc cgaaagccca accttagcca
    13861 actcttcctt ggcaatctta gtcgcttctt ggtcagataa tttcttgaca acaaccaagc
    13921 cttctttcac attatcaagt gctgttcggc gttcaaacaa attaaactgt tggaaaacca
    13981 tagacaactt acgacgtagg gcaaggattt cttcttgagt gattttagaa aaatcaactg
    14041 aaaaaccatc aatctgaata gagccactgt caggtgtttc aagataattg agactgcgaa
    14101 gaaaggttga ttttccagct cctgaagaac caatcaaggc tacaacttcc cctttttgaa
    14161 tatccaagtc cagatgatcc aagacagtct gtcctgaaaa ggatttgctt aaattcgaaa
    14221 tcttaatcat taacgaaggt ctcctttcac atctgtttgc actgtatcag gtgcagaaat
    14281 agccattttt ctctcgatga aacgaccgag gctttcaatt ccgatattga ctacccaata
    14341 aacaagggca acggagatga agcgttcaaa atagcgataa tcagctccac ctagaatctg
    14401 agcttgggca aagacttcca caacacccgc actaaaagct agagatgttc ccttggtcaa
    14461 accgatgagg gaattaatca aggttggagt agctaccacc gctgcattag gaataatcac
    14521 tcgtcgataa acttgcgctc gggtcatacc cagactgcgt gccgcctcaa tctcaccagg
    14581 attaactgag agaatggctg cacgaatggt ttcactagca taagctgcct cattaaaggc
    14641 aaaggcgaca atcgcaaaag ctgcagctgg aatcgcattg atattgagac cagttcccca
    14701 ttgctgattg agggctttca aagccaaagg gattccgtag taggtcaaca tgagttgcac
    14761 caaaatcggt gtccctttta agaaactaac aaagaaggcc tgcaagggat ataaaatctt
    14821 gacacgattg atcttcacaa tggcaaaaag aagcgccaaa accaagccaa aaagggcacc
    14881 accaattgtc aacataattg ttgttggaag ttgttggaca attctaggga ttccatcaaa
    14941 gaccgaacgt aggctaaaca gcttgccatc cggaatcaat tgcatcaagt tttggtacca
    15001 atctgatgct aaaatcgttg taacattcat aaaaacatcc tcttctgata atgattcatt
    15061 ctaccatgct tctgccgtca atgaaattat ttgctacggt cagatacaga ctttgtctac
    15121 ctactagttt atcatacttt gaaacaggga agttatatat tttatctatc aaagagatag
    15181 ataaaaacta tttcagtccc agttcctcat aagattttcg ataaccgatt tgcttaacag
    15241 ttccattttc tactaaaatg ggccgtttta acaacatacc gtcacttgct agcaactcag
    15301 ccgcttcttg gtttgacaaa cttcctacct tatcttttag ccctaattca cggtatttga
    15361 taccactggt gttgaaaaat tgcttcaatt caaatcctga ggtttctagc caattcaaaa
    15421 tgacttcttg gctaggtgtt tcttccacga tatggacggc tttatagtcc acacctaatt
    15481 gatttaattc ttgttttgct tttttacaag ttgaacattt ggggtattcg ataaattcta
    15541 acatgtgctt ctccttctat tgcttctatc tttaaaatct actccttcat gctccaagag
    15601 ccaagctttc ttttccactc ctgcagcata acctgtcaga cgcttgcctg ctcccaacac
    15661 acgatgacaa ggtactagga tagaccaagg attgcgtccc actgctccac caattgcttg
    15721 agcagaagcc acttgcaggt cttgagcaat ttgtccatag gtcactgtct gaccataagg
    15781 aatgccctgt aaatagtccc aaactctctt ttcaaaattc gttccgattg gcgccaagag
    15841 caagttggat aaatcctgag gcttgccttt aaagtaatca tctaagcaag caataactgg
    15901 gtctaaaata ggatgactaa caacttcttc tatcgtttca tctcctagtc ccctctcaaa
    15961 atgcttctgc tcctgaaccc aaattccata caaataatgg tcatcagcta caagtgatag
    16021 aataccaatt ggtgaggagt agaggatttt tacatacttc ttttgcatta tttctttaat
    16081 ttttgatagg ccaagcgttc gccatctact ggcatcttac cgacttgttt aaaaccaagt
    16141 ttttcaaaaa tatgttgcat aaccttgttt tcagcatgcg tatctgagcg aaaatcaaga
    16201 taatcaaaac cttcaatcaa gccctctaag aaggtttgag caactccttt tccctgcaca
    16261 tctgctgcca cagcaatacg gtgaaagact agatactctg actctccagc ttgccagttt
    16321 ccctcataaa tagcttcata ggcctcctct ggactcttgg tcacagcagc ataggctagc
    16381 agttctccct cttccaaggc tacgtaggct tgccctgaga tgatatcatc gataataaca
    16441 tctgcatttg gatagccatt ttgccactgg tcactaccag catctgctaa acattttttg
    16501 gcatcctcca tcacctgcat gatggcatct acttcatttg gaaaagctaa acgaatttcc
    16561 atcttttttc ctcatttctg actagtttct cccatcatag cataatttaa gtatttctac
    16621 aagcagttaa aacttgactt tgtgtttttg ttattttata atctagttat caaaactata
    16681 taaaaaggag ttaaaaatga aaactacctt ttcctaccca aaatgggcag aaattccaaa
    16741 cattgacctc tatctggacc aggttttgct ctatgtcaat caggtctgcg cccctatctc
    16801 tcctaataaa gacaagggcc taacagcatc tatggtcaac aattatgtga aaaatggtta
    16861 cctgacaaag cctgacaaaa aaaaatacca acgccaacag attgcccgtt tgattgctat
    16921 cacaaccctc aagtctgtat tttctattca agaaatagcc cagacactta atactctaca
    16981 aactcaagca agttcagacc aactctacga tgcttttgtg gactacatga accaaggaat
    17041 tgacccagct aaccctatta tccaaaccag ctgccaaacc gttaaactct atcatcaaac
    17101 tctagactta atcgatcata ctcaagagga ggtaatccaa tgaacactag tcttaaactc
    17161 agcaaacaac tcagttttgg agaggagatt gctaatagcg tgacccatgc tgtgggtgca
    17221 gtcatcatgc ttatcttgct gcctatttca tccatctata gttatgaagc acacggattt
    17281 ttatcctcta tcggcgtttc cattttcgtc atcagtctct ttctcatgtt cctatcatcc
    17341 accatttatc actctatggc ctatggttcg acccacaaat atgttttgcg aatcattgac
    17401 cattctatga tttacgttgc cattgccggc tcatacacgc ccgttgtctt gaccttgatg
    17461 aataactggt ttggctatct gattattgtc atccaatggg gaacgaccat ctttggtatt
    17521 ctctataaaa tctttgctaa aaaggtcaat gagaaattta gccttgctct ttacctgatt
    17581 atgggctggt tggttctggc tatcattcct gccattatca gtcaaacgac acccgttttc
    17641 tggagtctca tggtaactgg cggactctgt tatacagttg gagctggatt ttatgccaag
    17701 aaaaaacctt atttccacat gatttggcat ctctttatcc tagctgcgtc cgcacttcaa
    17761 tacatcgcta ttgtttatta catgtaaaaa agttgagaaa ttcaatctca acttttttct
    17821 ttacacatat tgataaagta ctggtgcaag cgcacatcat cagtcaattc tggatgaaaa
    17881 gaacttacca acatattttt ttcttgggct gcaacaattt gattgttcac tgttgctaaa
    17941 atttctacac cctcaccaac actactgata atcggaccac ggataaagat cattggaatc
    18001 ttgccaactc ccttacattc tgcttccgtg tagaaacttc ctaattggcg cccataagca
    18061 ttacgctcga ccaccatatc catagttcct agatgactct ctttctgaga agtgatttcc
    18121 ttagccagca aaattaagcc cgcacaggtc ccaaacactg gtaagccaga tagaatggct
    18181 tctcggatgg gaagtagcat gttctggtca cgtaagagct tgcccatggt tgtagactca
    18241 ccaccaggca aaatcaaacc cgacaagtca ctctgatctt gctgaaaatc atctagattt
    18301 ctgagttcta cactctcgac acctaattga tctagcactt ttgcatgttc tgcaaaggcc
    18361 ccttgcaagg ccaatattcc gattttcatc tattttcctc gttcagccat gagaatttgg
    18421 atttcatttt cattaatacc aaccatggct tctcctaaat cttcagagat ttgagctagg
    18481 atttgaggat tacggaagtt agtcacagcc ttaacaatgg cactcgctcg tttaacagga
    18541 tctcctgact tgaaaatacc tgaaccgaca aagaccccct ctgcccctaa ttgcatcatt
    18601 aacgcagcat ctgctggcgt tgcaacacct ccagcagcga aatttacaac tggcaatttt
    18661 ccatgttcat gaacatattg gaccaattct acagggactt gcaaatcctt ggcagcaaca
    18721 taaagctcgt cctcacgtaa gttttgaatg cggcgaattt cctgattcat catacgcata
    18781 tgacgaacag cttggacgat atcccctgtc cctggttctc ctttggtacg aatcatggaa
    18841 gcaccttcag cgatacgacg caaggcttca cccaaatcct tagcaccaca gacaaaagga
    18901 acttggaatt ctttcttgtc cacatggaaa cggtcatcag ctggagatag aacttcactc
    18961 tcgtcgatat aatcaatttc aatagcctct aaaatctgag cttcaacaaa atgcccgatt
    19021 ctgaccttag ccattactgg aatactaacc gcttcttgga tttccttaat catctttggg
    19081 tcgctcatgc gggaaactcc tccagctgca cgaatatcag ccggaattcg ttccaaggcc
    19141 atcacagctg ccgcaccagc agcttctgcg atacgagcct gttcaggatt ctgcacatcc
    19201 ataataacac cacccttgag catctgtgcc aagtttttat ttagttcata acgattttca
    19261 gtcatttgtt ttatcctcat catttgtatt ggtagctacc ttttcatttt aagtcagaac
    19321 agaatgaagc acaagataaa aaaactataa ttgtatgggg acaaattagc taaaaactat
    19381 ctgaccttaa cttaaggcca gatagctcat tcatttttat ttttcagccg taagggcagc
    19441 cattgtgatg tagttgtatg gtttgttgaa gtgtggcaag aagaagaggt ctgtcaatgc
    19501 caatttatca attgtcacat gctcttggat agcaagtgag aacatgtgga ttcccatgct
    19561 aattgcaata tcatgtgaaa ccatttgggc accaagaatt tcacggctat ctttgtcaaa
    19621 gacaatctta attgctactt catggttgtc atgtttcatg aattctggtt tttgaagatc
    19681 gttaaagcct gtttcagttg cgttgtaacc agcagctttc gctttttcaa gagtcaaacc
    19741 agttgaaacc atgtgaagac cgtagattga gataccattt gaaccttgaa caccgattcc
    19801 ttccaattca tgtccacaag cattgtaggc accaacgata ccagtgcgaa cagcatttga
    19861 agcaagagcg atatagcttg tatctttacg agcattgtca taaacagtcg cacagtcacc
    19921 aacagcgtaa acgtctggga tagatgtttc ttgtttcttg tctacaagga aggcaccgtt
    19981 gcggaagagt tcgatcttac cacctgcaag ggctgtgttt ggacggaaac caactgcaag
    20041 gataaccata tccacgtcaa agctttcttt gtcagtaatc aagcgttcaa ctttaccgtc
    20101 accttcgatt gctttaacag tttgacctag agccaagcgg atgttgtgat cttccaagtt
    20161 cttcgccatc atttgtgtga agtctttgtc atagtaaccg ttcaagacag tatcaacgat
    20221 atcaacaagg acaacttctt ttccaagacg ttcaaaggct tcagcaagtt caacaccgat
    20281 gtaaccacca ccaacaacgg cgatacggtc gaggtgttgg ctcttgtcag aaagtttatt
    20341 gataacttct tcagcatttt ggtacaattt cacgaattgt acgttttcaa gagttgcttt
    20401 aaattcgcgg tttcctttaa caatttcaac accttcgatt ggtggcaaga ttggtgtaga
    20461 gcctgtagcg aaaatcaatt tttcgtatga ttctttgtgc tcttttcctt caacttccgc
    20521 tgtaactact ttgttatcat agtcgattga aagaacaggt gagttcatgt aaactttagc
    20581 acctttagct tccaattttt ctttatcaga atagaacaag ccttcagcac cgtcaatttg
    20641 ttcaccaatc caaagagcca ttccacatcc taggaaagag atgttagagt tttggtcaaa
    20701 tacaacaatt tcgttctcat ttccaaaatt atccaacatg gtattgatac atgctgtacc
    20761 agcgtggtta gcaccgacta caacgatttt actcataaaa atttcctgcc ttcattctaa
    20821 atttacctta ctagtatacc atttaccgtt agcgtttaca aggggggtac tattatttca
    20881 gcatttttta tcaaaaataa ttccccattt atcctgtttt caagcctgat gaattttatg
    20941 agcatatttc ttgacttttt ccaaattttg tttgtgaaaa ttctaacttt atggtattat
    21001 aataacatga aaatgaaatg taagggcttc aatttagatg attatttgat attacaactt
    21061 attttctata agagaaagga gttggtagct tgactcttcg ttcacattct gaacggctaa
    21121 tggggactac tatcactatt tcattagtgg atgagcaagc cgatatcttt ctccaaaaat
    21181 cctttgactt gctcaaagaa cttgaatacc gcttcaacgc caatagtcaa gaatctgagt
    21241 tgatggaaat caattatcaa gcaggaatag cccccgtcac ggttcatcca gacctgtttg
    21301 agctgatttc acttgggtta gagcatagcc tagcgctctc tagccacctc aatatcagca
    21361 ttggtccctt aattcaaacc tggcgtatcg gtttttcaga tgccaaggtc gcccagcctc
    21421 aagaaattga atcggtgctg cctctaatca atcctcatgg tatcgagtta gattcttcta
    21481 cttctactgt gtttttaaaa cagaaaggaa tgaagatcga tctaggttgt ttagccaaag
    21541 gatacagtgc ggataaggtt gcccaatttc ttaggaaaga gggggtgact tctgccttga
    21601 tcaatctggg agggaatatc ctgaccattg gaaaaaatca ggcaagaggg gataacccat
    21661 ggcaaatcgg gattcaagac ccagccaatc ctaggggaaa tcatttaatg accatccctg
    21721 ttgtcaataa atctgtcgtg acttcaggca tttatgaacg tcacctgacc gtcgatggac
    21781 aagattacca tcacattttt gacagtcaaa caggatatcc tgttgaaacg gaactagcga
    21841 gtctaacaat catctctgat aaatcagtcg atggcgaaat ctggacgact cgactctttg
    21901 gagaaagacc tgcttctatc ctctggcaag tcgaaagttt ggagggcatc gaagtcatcc
    21961 tcatcgataa agaaggccac ctaagctgtt cttcaggaat tcctactcta tagagacaac
    22021 tgtttcaatg gaattttaaa attgtattat gtaaaaagag aaaggaaatc tcatgttaaa
    22081 acttattgct attgttggaa caaattcaaa acgttctaca aaccgtcaat tgcttcaata
    22141 catgcaaaaa cactttactg acaaagctga aattgaactt gttgaaatca aggccattcc
    22201 tgtcttcaac aaaccagctg acaagcaagt acctgctgaa atattggaaa ttgctgctaa
    22261 aatcgaagag gcagatggcg ttattatcgg tactcctgag tatgatcact ctattccagc
    22321 tgttttgatg agcgctcttg cttggttgtc ttatggtatt tacccacttt tgaacaaacc
    22381 aatcatgatt acaggtgctt cttacggtac gcttggttca tctcgtgccc aattgcaact
    22441 tcgtcaaatc ttgaatgctc ctgaaatcaa ggcaaatgtt cttccagatg aattcttgct
    22501 ctcacactct cttcaagcat ttaacccaag tggcgacttg gttgaccttg atgttatcaa
    22561 gaaattggat gccatctttg atgacttccg tatctttgta aaaatcacag aaaaattacg
    22621 taatgcacaa gaattacttc gcaaagatgc tgaagacttt gactgggaaa atttgtaaga
    22681 taggagacca aaaagaatga aatttgttgg acttgttgga tcaaactacg atcaatcata
    22741 taaccgtaag ctcttggaat ttatccgtcg ctacttcaaa ctcaaatttg aattagaagt
    22801 tcttgaaatt gacgaagttc caatgtttaa ccaagatgaa aaatgggatg aaagtttcca
    22861 attacgttat ttatataaca aaattactcg tgcagatggt gttatcattg ctactcctga
    22921 gcataaccac actatctcag cttcactcaa atctgtactt gaatggcttt catacgaagt
    22981 tcatccattt gaaaacaagc ctgttatgat tgtgggtgca tcatactatg accaaggaac
    23041 atcacgtgct caagttcacc ttcgtaaaat ccttgatgct ccaggtgtta atgcctacac
    23101 gcttccaggt aacgaattcc ttcttggtaa agctaaggaa gcttttgata acaacggaaa
    23161 tatcaccaac gaaggcactg ttaaattcct tgaaacttgc ttagataact ttgttaaata
    23221 cgtaggagtc gtttcgaaat tgaaaaaacc aaaaccaatc gaatcagaag acttggattg
    23281 tggaaaacca atcgctacaa ccatcacaga agttgaccct gacgatccag aatgggtaga
    23341 aaaagttgca gcattcactg gtgctgtttc tggtgatacc tatgtcaaat tggaccacgg
    23401 tatcctaaca gttaaccaaa ttgatatgtt cttgaaagct atgccatttg aattgacata
    23461 cgctgacgac aacaaccaat tcctctacta caacaacgct caccaagatc cagacactat
    23521 gttcgctaaa cgtgtaccac ctcaatcagg tagccgtatg tcgactgttc atggttctct
    23581 tccaccagca cgtatgaaga acgtagagtg ggttatcgga acacttcgca acggaaacca
    23641 agaatacgtc cgtacgatcg ttccaggttc tcctgcaggt gttatcaaca ctcacaacta
    23701 ccaagcaatg tactatcctg atggatcata cgctggtatc aatgaaatcg tctttaactt
    23761 ccaaccatgg cttgactggt acctaaaaga gactggtcaa cgtttggtgg gtggtagcgg
    23821 accatttgct cctgctgccg gaggtcatgg agacgccgat gctacttctg gcgcttctga
    23881 ttcaggggat gctggaggcc acggtggtga cgcagacgct acagccggtg caagttacta
    23941 atgatagttt ttaggaacca ttatggttcc ttttttagcg aaaaaagact agcaaacaca
    24001 aactgctagt ctctttgtta tcgtttcatc tatctttgtt aaaagaaaga atacatatac
    24061 tcaatgaaaa tcaaagagca aactaggaag ctagccgcag gctgtactta agtacggcaa
    24121 ggtgaagctg acgtggtttg aatttgattt tcgaagagta ttattatgaa tttggatcat
    24181 caagactacg gccatgtaat cctttttcac gttgtacttg gcgtagtttt tctggtgtaa
    24241 catcgtttcc ttcttcgtcc acaattttga ttccttcaat gtggtgacga acagcgcggc
    24301 gataaccttc gatgtactcc tcacgtagtt tggcttgttc cactttttct tctggtgtta
    24361 agccttctgt ttttttcttt ttagcaagct cattgatacg agcaattttt ttcggatcca
    24421 tttcttctcc tttgtaataa gataaagtcc gtttatcaaa ttttatttag tgttaatttg
    24481 gttaaaacaa gcaaacttag ctgctttctt ggttagttgt gacaagattg ccaaacgatt
    24541 ttgacggaca gcctgatctt cagccattac catagtattt tcaaagaaag catcaatgac
    24601 tgggctaagc gcaaaaagtt gtttcaattg ctgacttgca ggtcctgata aaatgagtgt
    24661 ttctactgct tctgccaaag ctttttcttg gtcattctca aatagtgctg aatcaaccgt
    24721 agcaacccct tctgccttct cggccaggtt aaaggcacga gaaagtgatt caacagatgg
    24781 tttaaaatct tcttccttgc ttacttctac gagagcactt gctgcttcca acatatctgc
    24841 cacaacaaag tttgaacctg caagaactgc ttccttgata tcttttggag tagagcccat
    24901 catcttatca acacgagcct tgataaagtc cataacctct gctttatttt cataagtcaa
    24961 actgtcaaat ttcaatgcat aaaggctatc aatcagctca tccatagcaa tgtgccaacc
    25021 aaaggcatcc aagatacgaa ccacaccttg agttgcacga cgaagggcat aagggtcatt
    25081 agaacctgat ggaatcaatc ctactgagaa gaaactcaaa atcgtatcca atttgtctgc
    25141 aatggctaga actgcgccga ccttgctctc tggaagttct ccttcagctg atgtaggcat
    25201 gtagtgttca cgaatagcag ctgccaccgc tggagtttca ccagcaagaa gggtgtattt
    25261 ttcacccata attccttgga gttcgtcaaa ttcaccaacc atacctgtca acaagtcaaa
    25321 cttgtaaatg gctgctgcac gagcaaggtc aactgtttca tccactgaca aactagcttt
    25381 ttctgccaaa agtacagtga tttgacccgt acgaatcatg tgttcacgaa gagaaccaat
    25441 cttctcatgg aaggtgacat tgtttaattt ttcaacaaga tctgaaatca ccaatttttg
    25501 gtcttcacgc cagaagaatt ctccgtcttc caagcgggct accaagactt tttcatttcc
    25561 tttgatgaca tttttcaaac gctcttcgtt tccgttacga acagaaatga agtttggcaa
    25621 gagttttcca tcttgatcac gaacaacaaa gtaacgctgg tgttccttca tagaagtcac
    25681 caagacttct tctggaactt caaggtattt agcatcaaaa cttcccatga aggcagttgg
    25741 gtattcaacc aaattcaaga cttcattcag caaatccgca tcaatttcga tacgtacacc
    25801 atgttttgcc tcaatttcct tgatttggtc aacaatcatt tgctcacgtt cacatggatc
    25861 tgcgattaca aactgcttac gaaggtcttc ttcatagctc aatgctgact gaatcttggt
    25921 ttcttgtccc aaaaaacgat ggccacgact cacacgactt cccttgatat caaggaaatc
    25981 caagtcaaac tcttgctcat ccaagagaac agttaaagtg tgaacagggc ggatgtattc
    26041 aaagctattt cccgcccagt gcatgctgac agggaaagtc agtgacttca agacatccac
    26101 aatgcctgga acaatggctt caactgcttg accaatttct tccttagtga catagacata
    26161 ttcttcaccc ttgatttcac ggaattcgat atcttcaaca gtcaaacctt tcccacggac
    26221 aaatccttga gctgctttgg tgaagtttcc atcactatct aaggcaattt tctttgctgg
    26281 acccttgaaa tcttctgtta aatcagactg tttgtctgca agaccagtta cacgaacagc
    26341 caaacgacgt ggtgttgaga aagtttgaat ggcttcaaaa gacaggcgtt ttcccttgag
    26401 gaaggctgcc attttttcgc ctagttgttt ttcacttggc gtaacaacat aggctggtaa
    26461 ttcttcaaga ccgagttcta ctaataagtt ttttgtcatg ttttttctcc gaaaagtatc
    26521 tttttatttt ccagtttgcc ttatgtgatt ggcacgcaag caaccaactt cgttgtttca
    26581 ttgctaaaat tggagccaaa agtctccaat tttgcctagt atccttagtt tcactaagga
    26641 taccttcatc actgcggcaa ctggctcagg gctcactctg ttcgcccatt ttcgtaattt
    26701 gtcactctct ttattctgcg tcttctgcta ggagtttagc tcttgtttct tcatccaaaa
    26761 gtgggtagcc taggcgtttg cgttctgcga caaaggtttt ggctacgaca cgggccaagt
    26821 tacggatacg agcgatatag cctgcacgct ctgttacaga tacggcacca cgcgcgtcaa
    26881 gcagattaaa ggtatgtgaa catttgagaa catagtcata ggcagggtgt accaagcctt
    26941 cttctaatgc acgaccagct tctttttcaa acttatcaaa gttttcaagc aacatttctt
    27001 ggtccgaaat ttcaaatgaa tattttgagt gctcatactc aggctggata aagatttctc
    27061 cgtattttac accatcagcc cactcgatat catagacaga gtctacttct tgaatgtaag
    27121 aagccaagcg ctccaaacca taggtaactt ccgcagtcac agggccagtt gccaatccac
    27181 cgacttgttg gaaataagtg aactgagtga tttccattcc gtcaagccaa acttcccaac
    27241 caagaccagc tgaaccagtt gatgggtttt cccagttgtc ctcaacaaaa cgaatatcgt
    27301 gctccaaagg attgattccc aatttttcca aagactcaag gtaaagttct tggatatttg
    27361 atggagaagg cttcatgacc acctggaatt ggtggtgttg gtagagacgg ttagggtttt
    27421 ccccataacg accgtcagca ggacgacgtg atggctctac ataagctgca ttccatggct
    27481 caggtccgat agcacgaagg aaagtgtaag gactcattgt ccccgcacct ttttcattat
    27541 cataagcctg cataagcata caatcttggt cattccaaaa ttgttgcaaa gtcaaaataa
    27601 tttcttgaaa tgttaatttc ttagacattg aatactcctt aataaaaaat aatttcttgc
    27661 gacacgagtc tgcctcgtcg attatacgag gcaagacgag ttagtactgc gtctagctca
    27721 ggcactctag tgctgagcgt agggcagtcc gactgtaagg aggtttctgc cactgacgca
    27781 gtgaaatgtt aatttcttag acattgaata ctccttaata aaaaataatt acttgcgaca
    27841 cgagtctgcc tcgtcgatca tacgaggcaa gacgagttag tactgcgtct agctcaggca
    27901 ctctagtgct gagcgtggag cagcccgact gtaaggaggt ctctgccact gatgcagtga
    27961 aatgttaatt tcttagacat tgtttactcc tttagttttt atatttcttt ttcaattaat
    28021 ttctgctgaa caaaccaatc taacaaggga aaagtttttt ctgtatttgc ccataaatga
    28081 taagaatcta agaccgcttg tacactacct aaattttcta ccaacttatc tactgtcaaa
    28141 aagctgcgcc agtattcata aaaaatactt gcatagttct tatcataagt cgaagaacca
    28201 aaatcattca atgaatgcca actatacttc ttctgaaaaa gttctacgag agattgatta
    28261 caaatttttt ccgcttgaaa ttcctcttct gtcaagaaat acttgcgact aatatattca
    28321 accatcccct cttcgaacca gatataagag tcataaccat caaaatcatc taaaaaatgt
    28381 ccgaccaatg agctaactca tgtcctacaa tctgtaagag gaaattttca gataaagaat
    28441 gatagtgact ttctattgct tgagtttgct cagaacactc gtagtccatc aactgataca
    28501 aatacaattc tttccaaaca gctaaatcag gcgtcataac cactcgtcta ttatttgtat
    28561 aggttggaac agcactttcc ctaataatct gtgtagcagc attaaaatct gaccaaataa
    28621 cagcttgcgg taaatcacag actgcaagtt cattctttaa aaaagattga taatctttca
    28681 acttttcagt atttcttact acaaaatcac gaaatgtagc tagttgacta tcgtctttta
    28741 caagataaag gttgtccacg gctctccttt ctttcacaca atagactgaa taagcaaaag
    28801 aaccacatct gacaatccta ggttgattta acctaggggc gtcagaaacg cggttccacc
    28861 ctaatttatt acttcattgt ttttgaaaat actacagaaa gcgccagccc tttattttgc
    28921 cctacttggc tcccactatc ccaagctcgc ttgaagaacg ccataagact ttctttcctg
    28981 ctgactatta tatcaaaaat tagaataatg tacaattctt tttatgattt tctagaaatc
    29041 cacatcatca actcgtggag cacccgattg aacagcaatc gtttttaagg tttctctctc
    29101 ctcatgactc agttcaattc caaagcaatc aagattagct tgaatacgag aggttgtgac
    29161 agattttgga agtggtaaaa atccttctgc caagctccag gccaaggcta tctgagcaac
    29221 cgattttccg tgatttgctg ctatttcttg gacttgcttg ctatcaaaca gttctccttg
    29281 tccaaaaggc ccccaagctt ccaataaaat tcccttttca cgacagtaag ctacgacttg
    29341 atcttgatac acacctggcg ccaagcgaac ttgattgacc gcaggaacga tagttgcagt
    29401 ttcaagcaag gcatccaaat gatggggaag aaaattgcta acgccgatag cacggatttt
    29461 cccttcttga tagaggtctt ccatcgctct ccaaacttcc gcattgcgag ttttccatgc
    29521 gtcattttct ctgagcggtt ttgggttcgg ccaatgaatc aaatacaaat ccaaataatc
    29581 caagcccagt ttttctatag atttttccaa agcttgacga gtttgctcat aggtttgctg
    29641 actattccaa agcttggtag ttacgaacat ttcttcacgt ggaactccgc tatctttgat
    29701 tgcttgacca acactttctt cattctgata aatcgccgcc gtatcaatat gacgataacc
    29761 agccttcaag gcttctaaca ctgcacgata ggcttcttct ccatccttag ccttaaaagt
    29821 tccaaatccc aatactggaa tttctactcc attatttaat tgataggtat tcatatgctt
    29881 ctccttctat tttattcatc aattatagca taaaacattt tttaagtagt actatattct
    29941 gtaaaaaata agtctgtcaa atatctaaca gacctatttt ttcttgctta ttcatcacga
    30001 ctatagtaca gctcatgagc ttttaggcga gtattgagca tctctggtat ggtcacaaag
    30061 gtataacctt gatttttcaa atactcaatg acccttggca aggcattgac tgtcggactg
    30121 tgaatatcat gcatcaaaac gatagagcca ttagctactt gatgctgaat ttctgtcaaa
    30181 atagatgctt catttttact cttccagtcc agactatcca catcccacat gataaagctc
    30241 aaatccaagc tattgcgaat atcatctgta atagcaccat aaggtggacg catgagttta
    30301 gaactagaac ccagcacttt agttagcaca tcctcagtat cagtaatctg ctttttagct
    30361 tcatcaagag agagttgcga gagaatcgga tggctccagc tatggtttcc aacaacatga
    30421 ccttcagatt ttatcctctt caccaagtcc tcattcccag aaacattttt cccaagcaca
    30481 aagaaagtcg ctttaatatc atatttagct agggtctcta atacctgcgg ggtcgttgct
    30541 ggatttggac catcatcaaa ggttagagcg acaacttttt gatgtttctt atcaaagtaa
    30601 gattggtaca aggccgcatc tttttcgagt aagtacgaag attggataac atcaaagaaa
    30661 gcagatactg gcaaggctat ctcttctaaa ttttcaacca caggacttgg ataaaggata
    30721 atctgactat ccttgtaatc aaaattccat gcagacaagt cttggtcaga gaagtttttt
    30781 acaatctgct cactctggtc ttgctctatt tttttatcct ctatgaagga ggtcaactct
    30841 tttatcagct gttccttagc cttactagca tctgaaaaca gttggtcaag tgtaaaaggt
    30901 tgcccatctt ctgttaagtg aacctttcct agactggtct tttcagtctc ttcaatctta
    30961 aaagcaacta aatcatagat ttgtttggtc acattacgat taacgactcc ctttaaacct
    31021 gactcttctt gctctgtata gtagaaaaca agattgtcct tactttctag cttgtcctta
    31081 acatcttgat ttatcagctc cctaacagag gaaatcactt tctccccttg gagaggataa
    31141 taggcaatca cttcggcttg cccctgacga aaatgctcct tctgatttcc ctcactcaat
    31201 tgatcatctt tctctttttt gagcgattca atcttttgct caaaactttt ttgctggtag
    31261 atcttaaaag caataaatcc gcctaatagg caaatagaaa ttgctaaaat accaatcaaa
    31321 gccaataata catgtctcgt tttcccgtgt ctgccacgtc ctagtctact tttattcata
    31381 tttatatcat aacaaatttg agcaataatt tcaatgatac aatttggcaa tccacaattc
    31441 ctctagcaag ccaaagcatc ttacatcaac tccaacatcc gtatctgtag agattatgta
    31501 gttttctatc tatggaattt ctagtagatt gaagctagaa tagtagacct atacttctaa
    31561 aacattgtta gaaatcgatt tgaccgtcct gatcgatttg tcctgttctc atttcatttt
    31621 actataaaac tatgaaaagc taggtcatct gagaagtaat tactatcgac aattgcgata
    31681 gcgtatacta gtgcgatttg tttgtagctc tggtgggtat caccttcacg ttggcgaatt
    31741 ttttctaggt tttgattaac ctgactgcac agataaggcc ataggcgatt gatgaaaaaa
    31801 ttctgatgat gaacctgaat ttcgatgata acttggattc cattatctaa ctccgccaag
    31861 acgtctatac tagtatagaa atcttacgct gagtagggca tggaaggcaa gacgtgaatg
    31921 ttacttccct ccaaaatcgt cacatttttt gctggcaagt ccagcatatc gcggataaat
    31981 tgacaaatca ttagttgggc tgatacctag atgtctgaga atcctccttt tcctccttct
    32041 attatagcac atttttaaat ctaggtttgc tagattctat gcttctatct atttattcgg
    32101 aaaagaaagc taatagctta tttgaaattt tctcctctct gttggatagt cccgtctatc
    32161 tatgttataa tgaaagaagg atttaaaatc ggaaaaggag tatttatgct aaaattaggt
    32221 gtcatcggaa ctggcgctat cagccatcat ttcatagaag cagcccatac cagtggagaa
    32281 taccaactgg tcgcaatcta ttctagaaaa ctagaaactg cagcaacctt tgcttctcgc
    32341 tatcagaata tccaactatt cgatcaatta gaagtcttct tcaaatcttc ttttgattta
    32401 gtctatatcg ccagtccaaa ctccttacat tttgctcagg caaaagctgc cttgtctgct
    32461 ggtaaacatg ttattctcga aaagccagct gtctctcaac cacaagaatg gtttgatttg
    32521 attcaaacag ctgaaaaaaa taactgtttt atctttgaag cagctcgtaa ttaccacgag
    32581 aaagccttta ctactatcaa aaacttttta gcagataagc aagtgttagg agcagatttc
    32641 aactatgcca aatactcttc caagatgcct gacttgttgg ctggacaaac accaaatgtc
    32701 ttttcagacc gttttgctgg tggagccctc atggatttgg ggatttatcc cctctatgct
    32761 gctgttcgtc tttttggaaa agccaatgac gcgacttacc atgctcaaca gcttgacaat
    32821 agcattgacc taaatggaga tggtatcctc ttctacccag actatcaagt tcacatcaag
    32881 gctggaaaaa acatcacttc caatcttcct tgcgagattt atacaacaga tggaaccttg
    32941 actctcaaca cgattgagca tattcgctca gctattttta ccgaccacca aggaaatcaa
    33001 gtccagcttc ctatccaaca ggctcctcat acgatgactg aggaagtcgc tgcatttgca
    33061 cacatgattc agcaaccaga tctgaatctc taccaaactt ggctgtatga tgcaggctct
    33121 gttcatgagc tactatatac catgcgccag actgctggca ttagatttga ggcagaaaaa
    33181 tgaaaaccaa actaccgact gaatggcaag aactgagtga ccaactcggt ttccaagaat
    33241 tcacccccat tcaaactcaa ctatttgagc cccttcttgc tggagaaaac ctcctaggag
    33301 tgagccaaac cggaactggt aagaccctag cgtatctcct accaagtctt ctcagactac
    33361 aaaagaaaaa agcccaacaa ctcttgattc tagcaccaaa cacggaactt gctggacaga
    33421 tttttgatgt atgtaaaacg tgggcagaag ctatcggatt gactgctcaa ctcttccttt
    33481 caggttcaag tcagaaacga caaattgaac gtcttaaaaa ggggccagaa attctgattg
    33541 gaactcctgg ccgtatcttt gaactcatta aacttaaaaa aatcaagatg atgaatgtgg
    33601 aaaccatcat cctggatgaa tttgaccaat tactagatga ttctcagatt cactttgtag
    33661 aaaaaatcac tcactacgca cctcgtgacc accaactggt ctacatgagt gccacgacca
    33721 agtttgacca agaaaagatt gtgccgaata cacgcactat taatctctct gaccaaaaat
    33781 tggacaatat ccagcatttc tacatgcagg tagaccaacg tcatcgagtg gatatgctac
    33841 gaaaactggc tcatgtagag gatttccgtg gtctagtctt cttcaatagc ctgtcagacc
    33901 ttgggaatgc cgaggaaaaa ctacagtatc gtgatatatt gactgtttcc ctcgctagtg
    33961 atgttaatgt taaatttaga aaaatcatct tagaaaagtt taaagataac caactaaccc
    34021 tgcttcttgc aactgacctt ttggctcgtg gaattgatat cgatagccta gaatgtgtcg
    34081 taaactttga tattcctaga gatagcgaaa cctacacaca ccgtgctggc cgtactggcc
    34141 gtatgggcaa ggaaggatat gttattactc tcgtcactca tccagaagaa atcaaaaaac
    34201 ttaaaaagtt tgcaagtatc cgagaaattg tcctaaaaaa ccaagaactc tatatcaaat
    34261 aaagccccat tgctctatac acatccagtg tatggagctt ttttataagc aattcaattt
    34321 tatactcatc tgctttcaaa aagcattcta ttccatctcc gattaacgat ggactttatc
    34381 acctccttct ccagtccttg tatgacatct tggagttgat tcatgacatc ttccaaagtt
    34441 cgaaaggcct tattcttaaa tccacgttta cgaatctctt tccacacttg ttcaatgggt
    34501 tcatctctgg tgtgtatgga ggaataaagg taaaatcaat attagtcgga atctttaagg
    34561 tacttgattt atgccatata gcattgtcca taacgagtaa aaaataatca tctggataag
    34621 cttgtgaaag ctcttctaaa aagacgttca tccactcagt attacatcca ccagctatta
    34681 agaaaaatga ttcgcctgta tggggcatca acagctccat aacaatagcg aaattctcgt
    34741 atatagtgac tatggacatg tggacctact cctattggag accaacaaga tcccagttta
    34801 ctgattctac cgaaaccagc ctcatcttgg tacatcaagc gaaccttatg aaaaggtcta
    34861 ctggttttaa agcgctttct tgtcttcttg aattgagatt ttatttttag acgcgacaat
    34921 ggtttgagcg tctgctttcc taggatgttc tggacgtggc ataatatttc gccaaccatg
    34981 gtgcttcaac agttgataga aggcatcacg tgtgtaggaa cgatataagc ctgaaataag
    35041 gtattgtaac aaattctcct gcctctgtag ccttcaaatg gcgggcaaga aaggctttct
    35101 cttcctcaac tgtcatatat gcatggttac gaccaccacg tgtttcttga aggagagagt
    35161 cgagtccgaa ctcctc
//
LOCUS       DBEJAU010000015        34602 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC323 isolate 683620
            SAMN38261939-rid24807223.denovo.015, whole genome shotgun sequence.
ACCESSION   DBEJAU010000015 DBEJAU010000000
VERSION     DBEJAU010000015.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261939
            Sequence Read Archive: SRR26833919
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 34602)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 34602)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576303.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576303.1
            Genome Coverage       :: 154x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/19/2025 01:05:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,121
            CDSs (total)                      :: 2,078
            Genes (coding)                    :: 1,943
            CDSs (with protein)               :: 1,943
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 36
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 72 of 135
            Pseudo Genes (incomplete)         :: 63 of 135
            Pseudo Genes (internal stop)      :: 51 of 135
            Pseudo Genes (multiple problems)  :: 46 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..34602
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261939-rid24807223.denovo.015"
                     /strain="GPSC323"
                     /isolate="683620"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            762..1214
                     /locus_tag="ACL29Z_000811"
     CDS             762..1214
                     /locus_tag="ACL29Z_000811"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000587452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhcH/YjgK/YiaL family protein"
                     /protein_id="HGR0069145.1"
                     /translation="MIITKISRLGTYVGVNPHFATLIDFLEKTGLENLTEGSIAIDGN
                     RLFGNCFTYLADGQAGAFFETHQKYLDIHLVLENEEAMAVTSPENVSVTQEYDEEKDI
                     ELYTGKVEQLVHLRAGECLITFPEDLHQPKVRINDEPVKKVVFKVAIS"
     gene            1233..2570
                     /locus_tag="ACL29Z_000812"
     CDS             1233..2570
                     /locus_tag="ACL29Z_000812"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000738772.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HGR0069146.1"
                     /translation="MKKMRKFLCLAGIALAAVALVACSGKKEATTSTEPPTELSGEIT
                     MWHSFTQGPRLESIQKSADAFMQKHPKTKIKIETFSWNDFYTKWTTGLANGNVPDIST
                     ALPNQVMEMVNSDALVPLNDSIKRIGQDKFNETALNEAKIGDDYYSVPLYSHAQVMWV
                     RTDLLKEHNIEVPKTWDQLYEASKKLKEAGVYGLSVPFGTNDLMATRFLNFYVRSGGG
                     SLLTKDLKADLTSQLAQDGIKYWVKLYKEISPQDSLNFNVLQQATLFYQGKTAFDFNS
                     GFHIGGINANSPQLIDSIDAYPIPKIKESDNDQGIETSNIPMVVWKNSKHPEVAKAFL
                     EALYNEEDYVKFLDSTPVGMLPTIKGISDSAAYKENETRKKFKHAEEVITEAVKKGTA
                     IGYENGPSVQAGMLTNQHIIEQMFQDIITNGTDPMKAAKEAEKQLNDLFEAVQ"
     gene            2649..3533
                     /locus_tag="ACL29Z_000813"
     CDS             2649..3533
                     /locus_tag="ACL29Z_000813"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011999669.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HGR0069147.1"
                     /translation="MVKERNLTRWIFVLPAMIIVGLLFVYPFFSSIFYSFTNKHLIMP
                     NYKFIGLANYKAVLSDPNFFNAFFNSIKWTVFSLVGQVLVGFVLALALHRVRHFKKLY
                     RTLLIVPWAFPTIVIAFSWQWILNGVYGYLPNLIVKLGLMEHTPAFLTDSTWAFLCLV
                     FINIWFGAPMIMVNVLSALQTVPEEQFEAAKIDGASSWQVFKFIVFPHIKVVVGLLVV
                     LRTVWIFNNFDIIYLITGGGPANATTTLPIFAYNLGWGTKLLGRASAVTVLLFIFLVA
                     ICFIYFAIISKWEKESRK"
     gene            3533..4366
                     /locus_tag="ACL29Z_000814"
     CDS             3533..4366
                     /locus_tag="ACL29Z_000814"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016250560.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HGR0069148.1"
                     /translation="MKKKSGIYLDILSHVLLVGSTIVAVFPLVWIIISSVKGKGELTQ
                     YPTRFWPEQFTLDYFTHVINDLHFIDNIRNSLIIALATTLIAIIISAMAAYGIVRFFP
                     KLGAIMSRLLVITYIFPPILLAIPYSIAIAKVGLTNSLFGLMMVYLSFSVPYAVWLLV
                     GFFQTVPIGIEEAARIDGANKFVTFYKVVLPIVAPGIVATAIYTFINAWNEFLYALIL
                     INNTGKMTVAVALRSLNGSEILDWGDMMAASVIVVLPSIIFFSIIQNKIASGLSEGSV
                     K"
     gene            4384..6477
                     /gene="nanB"
                     /locus_tag="ACL29Z_000815"
     CDS             4384..6477
                     /gene="nanB"
                     /locus_tag="ACL29Z_000815"
                     /EC_number="3.2.1.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001042179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="neuraminidase NanB"
                     /protein_id="HGR0069149.1"
                     /translation="MNKRGLYSKLGISVVGISLLMGVPTLIHANELNYGQLSISPIFQ
                     GGSYQLNNKSIDISPLLLDKLSGESQTVVMKFKADKPNSLQALFGLSNSKAGFKNNYF
                     SIFMRDSGEIGVEIRDAQKGINYLFSRPASLWGKHKGQAVENTLVFVSDSKDKTYTMY
                     VNGIEVFSETVDTFLPISNINGIDKATLGAVNREGKEHYLAKGSIDEISLFNKAISDQ
                     EVSNIPLSNPFQLIFQSGDSTQANYFRIPTLYTLSSGRVLSSIDARYGGTHDSKSKIN
                     IATSYSDDNGKTWSEPIFAMKFNDYEEQLVYWPRDNKLKNSQISGSASFIDSSIVEDK
                     KSGKTILLADVMPAGIGNNNANKADSGFKEINGHYYLKLKKNGDNDFRYTVRENGVVY
                     DETTNKPTNYTINDKYEVLEGGKSLTVEQYSVDFDSGSLRERHNGKQVPMNVFYKDSL
                     FKVTPTNYIAMTTSQNRGESWEQFKLLPPFLGEKHNGTYLCPGQGLALKSSNRLIFAT
                     YTSGELTYLISDDSGQTWKKSSASIPFKNATAEAQMVELRDGVIRTFFRTTTGKIAYM
                     TSRDSGETWSEVSYIDGIQQTSYGTQVSAIKYSQLIDGKEAVILSTPNSRGGRKGGQL
                     VVGLVNKEDDSIDWKYHYDIDLPSYGYAYSAITELPNHHIGVLFEKYDSWSRNELHLS
                     NVVQYIDLEINDLTK"
     gene            6489..7592
                     /locus_tag="ACL29Z_000816"
     CDS             6489..7592
                     /locus_tag="ACL29Z_000816"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000241731.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HGR0069150.1"
                     /translation="MVKYGVVGAGYFGAELARYMQKNDGAEITLLYDPDNAEAIAEEL
                     GAKVASSLDELVSSDEVDCVIVATPNNLHKEPVIKAAQHGKNVFCEKPIALSYQDCRE
                     MVDACKENNVTFMAGHIMNFFNGVHHAKELINQGVIGDVLYCHTARNGWEEQQPSVSW
                     KKIREKSGGHLYHHIHELDCVQFLMGGMPETVTMTGGNVAHEGEHFGDEDDMIFVNME
                     FSNKRFALLEWGSAYRWGEHYVLIQGSKGAIRLDLFNCKGTLKLDGQESYFLIHESQE
                     EDDDRTRIYHSTEMDGAIAYGKPGKRTPLWLSSVIDKEMRYLHEIMEGAPVSEEFAKL
                     LTGEAALEAIATADACTQSMFEDRKVKLSEIVK"
     gene            7765..8463
                     /locus_tag="ACL29Z_000817"
     CDS             7765..8463
                     /locus_tag="ACL29Z_000817"
                     /EC_number="5.1.3.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398897.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009385 - N-acylmannosamine-6-phosphate
                     2-epimerase activity [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA];
                     GO_process: GO:0006051 - N-acetylmannosamine metabolic
                     process [Evidence IEA];
                     GO_process: GO:0019262 - N-acetylneuraminate catabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmannosamine-6-phosphate 2-epimerase"
                     /protein_id="HGR0069151.1"
                     /translation="MPQISKEALIEQIKDGIIVSCQALPHEPLYTEAGGVIPLLVKAA
                     EQGGAVGIRANSVRDIKEIKEVTKLPIIGIIKRDYPPQEPFITATMKEVDELAELDIE
                     VIALDCTKRERYDGLEIQEFIRQVKEKYPNQLLMADTSIFEEGLAAVEAGIDFVGTTL
                     SGYTSYSPKVDGPDFELIKKLCDAGVDVIAEGKIHTPEQAKQILEYGVRGIVVGGAIT
                     RPKEITERFVASLK"
     gene            8482..9999
                     /locus_tag="ACL29Z_000818"
     CDS             8482..9999
                     /locus_tag="ACL29Z_000818"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000477452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HGR0069152.1"
                     /translation="MFKVLQKVGKAFMLPIAILPAAGLLLGIGGALSNPTTIATYPIL
                     DNSIFQSIFQVMSSAGEVVFSNLSLLLCVGLCIGLAKRDKGTAALAGVTGYLVMTATI
                     KALVKLFMAEGSAIDTGVIGALAVGIVAVYLHNRYNNIQLPSALGFFGGSRFVPIVTS
                     FSSILIGFVFFVIWPPFQQLLVSTGGYISQAGPIGTFLYGFLMRLSGAVGLHHIIYPM
                     FWYTELGGVETIAGQTVVGAQKIFFAQLADPAHSGLFTEGTRFFAGRFSTMMFGLPAA
                     CLAMYHSVPKNRRKKYAGLFFGVALTSFITGITEPIEFMFLFVSPVLYVVHAFLDGVS
                     FFIADVLNISIGNTFSGGVIDFTLFGILQGNAKTNWVLQIPIGLIWSVLYYIIFRWFI
                     TQFNVLTPGRGEEVDSKEISESADSTSNTADYLKQDSLQIIRALGGSNNIEDVDACVT
                     RLRVAVKEVNQVDKALLKQIGAVDVLEVKGGIQAIYGAKAILYKNSINEILGVDD"
     gene            10124..11452
                     /locus_tag="ACL29Z_000819"
     CDS             10124..11452
                     /locus_tag="ACL29Z_000819"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000672126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HGR0069153.1"
                     /translation="MKFRKLACTVLAGAAVLGLAACGNSGGSKDAAKSGGDGAKTEIT
                     WWAFPVFTQEKTGDGVGTYEKSIIEAFEKANPDIKVKLETIDFKSGPEKITTAIEAGT
                     APDVLFDAPGRIIQYGKNGKLAELNDLFTDEFVKDVNNENIVQASKAGDKAYMYPISS
                     APFYMAMNKKMLEDAGVANLVKEGWTTDDFEKVLKALKDKGYTPGSLFSSGQGGDQGT
                     RAFISNLYSGSVTDEKVSKYTTDDPKFVKGLEKATSWIKDNLINNGSQFDGGADIQNF
                     ANGQTSYTILWAPAQNGIQAKLLEASKVEVVEVPFPSDEGKPALEYLVNGFAVFNNKD
                     DKKVAASKKFIQFIADDKEWGPKDVVRTGAFPVRTSFGKLYEDKRMETISGWTQYYSP
                     YYNTIDGFAEMRTLWFPMLQSVSNGDEKPADALKAFTEKANETIKKAMKQ"
     gene            11704..12570
                     /locus_tag="ACL29Z_000820"
     CDS             11704..12570
                     /locus_tag="ACL29Z_000820"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001209417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HGR0069154.1"
                     /translation="MRETVISYAFLAPVLFFFVIFVLAPMVMGFITSFFNYSMTKFEF
                     VGLDNYIRMFKDPVFTKSLINTVILVIGSVPVVVLFSLFVASQTYHQNVIARSFYRFV
                     FFLPVVTGSVAVTVVWKWIYDPLSGILNFVLKSSHIISQNISWLGDKNWALMAIMIIL
                     LTTSVGQPIILYIAAMGNIDNSLVEAARVDGATEFQVFWKIKWPSLLPTTLYIAIITT
                     INSFQCFALIQLLTSGGPNYSTSTLMYYLYEKAFQLTEYGYANTIGVFLAVMIAIVSF
                     VQFKVLGNDVEY"
     gene            12586..13425
                     /locus_tag="ACL29Z_000821"
     CDS             12586..13425
                     /locus_tag="ACL29Z_000821"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398901.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HGR0069155.1"
                     /translation="MQSTEKKPLTAFTVISTIILLLLTVLFIFPFYWILTGAFKSQPD
                     TIVIPPQWFPKMPTMENFQQLMVQNPALQWMWNSVFISLVTMFLVCATSSLAGYVLAK
                     KRFYGQRILFAIFIAAMALPKQVVLVPLVRIVNFMGIHDTLWAVILPLIGWPFGVFLM
                     KQFSENIPTELLESAKIDGCGEIRTFWSVAFPIVKPGFAALAIFTFINTWNDYFMQLV
                     MLTSRNNLTISLGVATMQAEMATNYGLIMAGAALAAVPIVTVFLVFQKSFTQGITMGA
                     VKG"
     gene            13697..14149
                     /locus_tag="ACL29Z_000822"
     CDS             13697..14149
                     /locus_tag="ACL29Z_000822"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000575445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhcH/YjgK/YiaL family protein"
                     /protein_id="HGR0069156.1"
                     /translation="MIFDDLKNITFYKGIHPNLDKAIDYLYQHRKDSFELGKYEIDGD
                     KVFLVVQENVLNQVENNRFEHHKNYADLHLLIEGHEYSSYGSRIKDEAVAFDEASDIG
                     FVHCHEHYPLLLGYHNFAIFFPGEPHQPNGYAGMEEKVRKYLFKILID"
     gene            14246..14590
                     /locus_tag="ACL29Z_000823"
     CDS             14246..14590
                     /locus_tag="ACL29Z_000823"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000254916.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0069157.1"
                     /translation="MVSSKYAARASFLDGQGITVDEMAWIIRGIVTALIGRYIKLGTY
                     AVKYGISMARSILSRAAATAAARVGLLTKIFGWILRIAVLAADVYGNFANNIAVAWDA
                     HDKIPNNGRINF"
     gene            14600..14794
                     /locus_tag="ACL29Z_000824"
     CDS             14600..14794
                     /locus_tag="ACL29Z_000824"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0069158.1"
                     /translation="MKALCIFLLYMLAWTVLAMIIRGGLDGFDEHTWRNILASALSSL
                     YIHYISIDRKRKKSKRKKKK"
     gene            14877..15521
                     /locus_tag="ACL29Z_000825"
     CDS             14877..15521
                     /locus_tag="ACL29Z_000825"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000057467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YesL family protein"
                     /protein_id="HGR0069159.1"
                     /translation="MAQKGVSLIKAAFDTDNFLMRFSEKVLDIVTANLLFVVSCLPIV
                     TIGVAKISLYETMFEVKKSRRVPVFKIYLRSFKQNLKLGLQLGLMELGIVFLTLSDLY
                     LFWGQTALPFQLLKAICLGILIFLTIVMLASYPIAARYDLSWKEILQKGLMLASFNFP
                     WFFLMLAILVLIVMVLYLSAFSLLLGGSVFLLFGFGLLVFIQTGLMEKIFAKYQ"
     gene            15690..16607
                     /locus_tag="ACL29Z_000826"
     CDS             15690..16607
                     /locus_tag="ACL29Z_000826"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002894436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016829 - lyase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrodipicolinate synthase family protein"
                     /protein_id="HGR0069160.1"
                     /translation="MSDLKKYEGVIPAFYACYDDQGEVSPERTRALVQYFIDKGVQGL
                     YVNGSSGECIYQSVEDRKLILEEVMAVAKGKLTIIAHVACNNTKDSMELARHAESLGV
                     DAIATIPPIYFRLPEYSVAKYWNDISSAAPNTDYVIYNIPQLAGVALTPSLYTEMLKN
                     PRVIGVKNSSMPVQDIQTFVSLGGEDHIVFNGPDEQFLGGRLMGARAGIGGTYGAMPE
                     LFLKLNQLIADKDLETARELQYAINAIIGKLTSAHGNMYGVIKEVLKINEVLNIGSVR
                     SPLTPVTEEDRPVVEAAAALIRETKERFL"
     gene            16625..17509
                     /locus_tag="ACL29Z_000827"
     CDS             16625..17509
                     /locus_tag="ACL29Z_000827"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HGR0069161.1"
                     /translation="MTYYVAIDIGGTNIKYGLVDQEGQLLESHEMPTEAHKGGPHILQ
                     KTKDIVASYLEKGPVAGVAISSAGMVDPDKGEIFYAGPQIPNYAGTQFKKEIEESFTI
                     PCEIENDVNCAGLAEAVSGSGKGASVTLCLTIGTGIGGCLIMDRKVFHGFSNSACEVG
                     YMHMQDGAFQDLASTTALVKYVAEAHGEDVDQWNGRRIFKEATEGNKICMEGIDRMVD
                     YLGKGLANICYVANPEVVILGGGIMGQEAILKPKIRTALKEALVPSLAEKTRLEFAHH
                     QNTAGMLGAYYHFKTKQS"
     gene            complement(17525..18376)
                     /locus_tag="ACL29Z_000828"
     CDS             complement(17525..18376)
                     /locus_tag="ACL29Z_000828"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0097367 - carbohydrate derivative binding
                     [Evidence IEA];
                     GO_process: GO:1901135 - carbohydrate derivative metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HGR0069162.1"
                     /translation="MDKPDIATIIDSHFEEMTDLEQEIARYFLQAETITDDLSSQQVT
                     QKLHISQAALTRFAKKCGFTGYREFIFQYQHQAENQANQVSKHSPLTKRVLRSYSNMR
                     EQTQDLIDEIQLERIAQLIEDAERIYFFGTGSSGLVAREMKLRFMRLGVVCEALTDQD
                     GFAWTTSIMDENCLVLGFSLSGSTPSILDSLLDAKEMGAKTVLFTSVPNKDSQTYTET
                     VLVATHSQPSYIQRISAQLPMLFFIDLIYAYFLEINRESKEKIFNSYWENKKLNGYRR
                     QKRVRKS"
     gene            18576..20633
                     /gene="pbp2b"
                     /locus_tag="ACL29Z_000829"
     CDS             18576..20633
                     /gene="pbp2b"
                     /locus_tag="ACL29Z_000829"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001829432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein 2B"
                     /protein_id="HGR0069163.1"
                     /translation="MRLICMRKFNSHSIPIRLNLLFSIVILLFMTIIGRLLYMQVLNK
                     DFYEKKLASASQTKITSSSARGEIYDASGKPLVENTLKQVVSFTRSNKMTATDLKETA
                     KKLLTYVSISSPNLTERQLADYYLADPEIYKKIVEALPSEKRLDSDGNRLSESELYNN
                     AVDSVQTSQLNYTEDEKKEIYLFSQLNAVGNFATGTIATDPLNDSQVAVIASISKEMP
                     GISISTSWDRKVLETSLSSIVGSVSSEKAGLPAEEAEAYLKKGYSLNDRVGTSYLEKQ
                     YEETLQGKRSVKEIHLDKYGNMESVDTIEEGSKGNNIKLTIDLAFQDSVDALLKSYFN
                     SELENGGAKYSEGVYAVALNPKTGAVLSMSGIKHDLKTGELTPDSLGTVTNVFVPGSV
                     VKAATISSGWENGVLSGNQTLTDQSIVFQGSAPINSWYTQAYGSFPITAVQALEYSSN
                     TYMVQTALGLMGQTYQPNMFVGTSNLESAMEKLRSTFGEYGLGTATGIDLPDESTGFV
                     PKEYSFANYITNAFGQFDNYTPMQLAQYVATIANNGVRVAPRIVEGIYGNNDKGGLGD
                     LIQQLQPTEMNKVNISDSDMSILHQGFYQVAHGTSGLTTGRAFSNGALVSISGKTGTA
                     ESYVADGQQATNTNAVAYAPSDNPQIAVAVVFPHNTNLTNGVGPSIARDIINLYQKYH
                     PMN"
     gene            20644..21240
                     /gene="recR"
                     /locus_tag="ACL29Z_000830"
     CDS             20644..21240
                     /gene="recR"
                     /locus_tag="ACL29Z_000830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002896112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="recombination mediator RecR"
                     /protein_id="HGR0069164.1"
                     /translation="MLYPTPIAKLIDSYSKLPGIGIKTATRLAFYTIGMSADDVNEFA
                     KNLLSAKRELTYCSICGRLTDDDPCSICTDPTRDQTTILVLEDSRDVAAMENIQEYHG
                     LYHVLHGLISPMNGISPDDINLKSLMTRLMDSEVSEVIVATNATADGEATSMYLSRLL
                     KPAGIKVTRLARGLAVGADIEYADEVTLLRAIENRTEL"
     gene            21416..22459
                     /locus_tag="ACL29Z_000831"
     CDS             21416..22459
                     /locus_tag="ACL29Z_000831"
                     /EC_number="6.3.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000814683.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--D-alanine ligase"
                     /protein_id="HGR0069165.1"
                     /translation="MKQTIILLYGGRSAEREVSVLSAESVMRAVNYDRFTVKTFFISQ
                     SGDFIKTQEFSHAPGQEDRLMTNETIDWDKKVAPSAIYEEGAVVFPVLHGPMGEDGSV
                     QGFLEVLKMPYVGCNILSSSLAMDKITTKRVLESAGIAQVPYVAIVEGDDVTAKIAEV
                     EEKLAYPVFTKPSNMGSSVGISKSENQEELRQALKLAFRYDSRVLVEQGVNAREIEVG
                     LLGNYDVKSTLPGEVVKDVAFYDYDAKYIDNKITMDIPAKISDDVVAVMRQNAETAFR
                     AIGGLGLSRCDFFYTDKGEIFLNELNTMPGFTQWSMYPLLWDNMGISYPELIERLVDL
                     AKESFDKREAHLI"
     gene            22543..23916
                     /gene="murF"
                     /locus_tag="ACL29Z_000832"
     CDS             22543..23916
                     /gene="murF"
                     /locus_tag="ACL29Z_000832"
                     /EC_number="6.3.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000778684.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0047480 -
                     UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase
                     activity [Evidence IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-
                     alanine ligase"
                     /protein_id="HGR0069166.1"
                     /translation="MKLTIHEIAQVVGAKNDISIFEDTQLEKAEFDSRLIGTGDLFVP
                     LKGARDGHDFIKTAFENGAAVTLSEKEVSNHPYILVDDVLTAFQSLASYYLEKTTVDV
                     FAVTGSNGKTTTKDMLAHLLSTRYKTYKTQGNYNNEIGLPYTVLHMPEGTEKLVLEMG
                     QDHLGDIHLLSELARPKTAIVTLVGEAHLAFFKDRSEIAKGKMQIADGMASGSLLLAP
                     ADPIVEDYLPTDKKVVRFGQGAELEITDLVERKDSLTFKANFLEQALDLPVTGKYNAT
                     NAMIASYVALQEGVSEEQIHQAFQGLELTRNRTEWKKAANGADILSDVYNANPTAMKL
                     ILETFSAIPANEGGKKIAVLADMKELGDQSIQLHNQMILSLSPDVLDTVIFYGEDIAE
                     LAQLASQMFPIGHVYYFKKTEDQDQFEDLVKQVKESLSANDQILLKGSNSMNLAMLVE
                     SLENETK"
     gene            23903..24514
                     /locus_tag="ACL29Z_000833"
     CDS             23903..24514
                     /locus_tag="ACL29Z_000833"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase N-terminal domain-containing
                     protein"
                     /protein_id="HGR0069167.1"
                     /translation="MKPSDFVKYLQRMIALTDTGLTFTKDPFDCERYEDLRSLLSEML
                     NQGSDLDAEEVAEVLKPTSAYATPLMDVRAWIVEDEKICLVRGQGEDSWALPGGFGEV
                     GYSPTENILKEIEEETGFKAKVERLLAVFDTNRFQLQSKQYAKFVFECKLLDGQFQEN
                     QEIADLQFFAIDQLPNLSEKRITKEQIEILWQVYQGQREQYLD"
     gene            24605..25309
                     /locus_tag="ACL29Z_000834"
     CDS             24605..25309
                     /locus_tag="ACL29Z_000834"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001055242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR02206 family membrane protein"
                     /protein_id="HGR0069168.1"
                     /translation="MNLWDIFFTTQATEPPKFDLFWYVSLFTLLALTFYTAHRYREKK
                     VYQRFFQILQTVQLILLYGWYWVNHMPLSESLPFYHCRMAMFVVLLLPGQSKYKQYFA
                     LLGTFGTLAAFVYPVPDAYPFPHITILSFIFGHLALLGNSLVYLLRQYNARLLDVKGI
                     FLMTFALNALIFVVNLVTGGDYGFLTKPPLVGDHGLVANYLLVSIVLVATISLTKKIL
                     EFFLAQEAEKMIAKEA"
     gene            25528..26901
                     /gene="ftsA"
                     /locus_tag="ACL29Z_000835"
     CDS             25528..26901
                     /gene="ftsA"
                     /locus_tag="ACL29Z_000835"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000090410.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005515 - protein binding [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0043093 - FtsZ-dependent cytokinesis
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsA"
                     /protein_id="HGR0069169.1"
                     /translation="MAREGFFTGLDIGTSSVKVLVAEQRNGELNVIGVSNAKSKGVKD
                     GIIVDIDAAATAIKSAISQAEEKAGISIKSVNVGLPGNLLQVEPTQGMIPVTSDTKEI
                     TDQDVENVVKSALTKSMTPDREVITFIPEEFIVDGFQGIRDPRGMMGVRLEMRGLLYT
                     GPRTILHNLRKTVERAGVQVENVIISPLAMVQSVLNEGEREFGATVIDMGAGQTTVAT
                     IRNQELQFTHILQEGGDYVTKDISKVLKTSRKLAEGLKLNYGEAYPPLASKETFQVEV
                     IGEVEAVEVTEAYLSEIISARIKHILEQIKQELDRRRLLDLPGGIVLIGGNAILPGMV
                     ELAQEVFGVRVKLYVPNQVGIRNPAFAHVISLSEFAGQLTEVNLLAQGAIKGENDLSH
                     QPISFGGMLQKTAQFVQSTPVQPAPAPEVESVAPTEPMADFQQASQNKPKLADRFRGL
                     IGSMFDE"
     gene            26918..28177
                     /gene="ftsZ"
                     /locus_tag="ACL29Z_000836"
     CDS             26918..28177
                     /gene="ftsZ"
                     /locus_tag="ACL29Z_000836"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000144288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_process: GO:0000910 - cytokinesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsZ"
                     /protein_id="HGR0069170.1"
                     /translation="MTFSFDTAAAQGAVIKVIGVGGGGGNAINRMVDEGVTGVEFIAA
                     NTDVQALSSTKAETVIQLGPKLTRGLGAGGQPEVGRKAAEESEETLTEAISGADMVFI
                     TAGMGGGSGTGAAPVIARIAKDLGALTVGVVTRPFGFEGSKRGQFAVEGINQLREHVD
                     TLLIISNNNLLEIVDKKTPLLEALSEADNVLRQGVQGITDLITNPGLINLDFADVKTV
                     MANKGNALMGIGIGSGEERVVEAARKAIYSPLLETTIDGAEDVIVNVTGGLDLTLIEA
                     EEASQIVNQAAGQGVNIWLGTSIDESMRDEIRVTVVATGVRQDRVEKVVAPQARSATN
                     YRETVKPAHSHGFDRHFDMAETVELPKQNPRRLEPTQASAFGDWDLRRESIVRTTDSV
                     VSPVERFEAPISQDEDELDTPPFFKNR"
     gene            28182..28853
                     /locus_tag="ACL29Z_000837"
     CDS             28182..28853
                     /locus_tag="ACL29Z_000837"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YggS family pyridoxal phosphate-dependent
                     enzyme"
                     /protein_id="HGR0069171.1"
                     /translation="MNVKENTELVFREVAEASLSAHRESGSVSVIAVTKYVDVPTAEA
                     LLPLGVHHIGENRVDKFLEKYEALKDRDVTWHLIGTLQRRKVKDIIQYVDYFHALDSV
                     KLAGEIQKRSDRVIKCFLQVNISKEESKHGFSREELLEILPELAGLDKIEYVGLMTMA
                     PFEASSEQLKEIFKAAQDLQREIQEKQIPNIPMTELSMGMSRDYKEAIQFGSTFVRIG
                     TSFFK"
     gene            28863..29402
                     /locus_tag="ACL29Z_000838"
     CDS             28863..29402
                     /locus_tag="ACL29Z_000838"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000053379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein SepF"
                     /protein_id="HGR0069172.1"
                     /translation="MSLKDRFDRFIDYFTEDEDSSLPYEKRDEPVFTPVNSSQEPALP
                     MNQPSQSAGTKENNITRLHARQQELANQSQRATDKVIIDVRYPRKYEDATEIVDLLAG
                     NESILIDFQYMTEVQARRCLDYLDGACHVLAGNLKKVASTMYLLTPVNVIVNVEDIRL
                     PDEDQQGEFGFDMKRNRVR"
     gene            29402..29665
                     /locus_tag="ACL29Z_000839"
     CDS             29402..29665
                     /locus_tag="ACL29Z_000839"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000576515.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YggT family protein"
                     /protein_id="HGR0069173.1"
                     /translation="MIFLIRMIYNAVDIYSLILVAFAVMSWFPGAYESSLGRWIVALV
                     KPVLAPLQRLPLQIAGLDLSVWVAIVLVRFLGENLVRFLAMIG"
     gene            29662..30447
                     /locus_tag="ACL29Z_000840"
     CDS             29662..30447
                     /locus_tag="ACL29Z_000840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding protein"
                     /protein_id="HGR0069174.1"
                     /translation="MNKGIYQHFSIEDRPFLDKGMEWIKKVEDSYAPFLTPFINPHQE
                     KLLKILAKTYGLACSSSGEFVSSEYVRVLLYPDYFQPEFSDFEISLQEIVYSNKFEYL
                     THAKILGTVINQLGIERKLFGDILVDEERAQIMINQQFLLLFQDGLKKIGRIPVSLEE
                     RPFTEKIDKLEQYRELDLSVSSFRLDVLLSNVLKLSRNQANQLIEKKLVQVNYHVVDK
                     SDYTVQVGDLISVRKFGRLRLLQDKGQTKKEKKKITVQLLLSK"
     gene            30456..31244
                     /gene="divIVA"
                     /locus_tag="ACL29Z_000841"
     CDS             30456..31244
                     /gene="divIVA"
                     /locus_tag="ACL29Z_000841"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001810114.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein DivIVA"
                     /protein_id="HGR0069175.1"
                     /translation="MPITSLEIKDKTFGTRFRGFDPEEVDEFLDIVVRDYEDLVRANH
                     DKNLRIKSLEERLSYFDEIKDSLSQSVLIAQDTAERVKQAAHERSNNIIHQAEQDAQR
                     LLEEAKYKANEILRQATDNAKKVAVETEELKNKSRVFHQRLKSTIESQLAIVESSDWE
                     DILRPTATYLQTSDEAFKEVVSEVLGEPIPVPIEEEPIDMTRQFSQAEMEELQARIEV
                     ADKELSEFEAQIKQEVEAPTPVVSPQVEEEPLLIQLAQCMKNQK"
     gene            31592..34384
                     /gene="ileS"
                     /locus_tag="ACL29Z_000842"
     CDS             31592..34384
                     /gene="ileS"
                     /locus_tag="ACL29Z_000842"
                     /EC_number="6.1.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012000155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004822 - isoleucine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006428 - isoleucyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="isoleucine--tRNA ligase"
                     /protein_id="HGR0069176.1"
                     /translation="MKLKDTLNLGKTEFPMRAGLPTKEPVWQKEWEDAKLYQRRQELN
                     QGKPHFTLHDGPPYANGNIHVGHAMNKISKDIIVRSKSMSGFYAPFIPGWDTHGLPIE
                     QVLSKQGVKRKEMDLVEYLKLCREYALSQVDKQREDFKRLGVSGDWENPYVTLTPDYE
                     AAQIRVFGEMANKGYIYRGAKPVYWSWSSESALAEAEIEYHDLVSTSLYYANKVKDGK
                     GVLDTDTYIVVWTTTPFTITASRGLTVGADIDYVLVQPAGEARKFVVAAELLTSLSEK
                     FGWADVQVLETYRGQELNHIVTEHPWDTAVEELVILGDHVTTDSGTGIVHTAPGFGED
                     DYNVGIANNLEVAVTVDERGIMMKNAGPEFEGQFYEKVVPTVIEKLGNLLLAQEEISH
                     SYPFDWRTKKPIIWRAVPQWFASVSKFRQEILDEIEKVKFHSEWGKVRLYNMIRDRGD
                     WVISRQRAWGVPLPIFYAEDGTAIMVAETIEHVAQLFEEHGSSIWWERDAKDLLPEGF
                     THPGSPNGEFKKETDIMDVWFDSGSSWNGVVVNRPELTYPADLYLEGSDQYRGWFNSS
                     LITSVANHGVAPYKQILSQGFALDGKGEKMSKSLGNTIAPSDVEKQFGAEILRLWVTS
                     VDSSNDVRISMDILSQVSETYRKIRNTLRFLIANTSDFNPAQDTVAYDELRSVDKYMT
                     IRFNQLVKTIRDAYADFEFLTIYKALVNFINVDLSAFYLDFAKDVVYIEGAKSLERRQ
                     MQTVFYDILVKITKLLTPILPHTAEEIWSYLEFETEDFVQLSELPEAQTFANQEEILD
                     TWAAFMDFRGQAQKALEEARNAKVIGKSLEAHLTVYPNEVVKTLLEAVNSNVAQLLIV
                     SDLTIAEGPAPEAALSFEDVAFTVERAAGEVCDRCRRIDPTTAERSYQAVICDHCASI
                     VEENFADAVAEGFEEK"
BASE COUNT        10657 a         6115 c         7499 g        10331 t
ORIGIN      
        1 tgactattaa ccttgtcttc tcctaaaatt gactttcttg ttttcttatc ttgtccactc
       61 gaaacaagta ttgtaagaat ttgattattt ttgaaagtac ttttaatata cttgatatag
      121 ttaaaaaaga tttgaaacta aattccaaat tagaaaaaga cttgaaatac taaaaaaaaa
      181 gtatactcta attgaaaacg gtaacaaaac taatttagag aatgaaatat agagtatttc
      241 tctcttaaaa gtttttggtg aaacgagatg tagaaaggag atttagccaa agagtctatt
      301 agtgctagaa taatagatta gaattatttt agaaaaacga agtgagcagc ttataaattc
      361 aagtccccaa atagattcat actagtatct tttgcaaaaa ataaagggcg acttccttca
      421 tgaatatcaa tttcatctat aaggaaggta gctaattgaa ctaacttatt tattctgttt
      481 gtcgctagaa aaatcagacc tccttgtgaa gattgaggag atactgaatg aaaatcaaag
      541 aagaaactag caagctagta gcagattgcc caaaacaccg ctttgaggtt gtagataaga
      601 ctgacctata taatccaagg tgaagcgact gtggtttgaa gagattttca aagagtatag
      661 gctagagagt agtgttttta tgtccttcta gtagaaaatg ctagacagaa gaatggggaa
      721 cttggatagg aaaaatagat tgagaaagga ggttagaaga gatgattatt acaaaaatta
      781 gccgtttagg aacttatgtg ggagtaaatc cacattttgc aacattaata gattttttag
      841 aaaaaacagg actagaaaat ttaacagaag gttcgattgc tatcgatggt aatcgattgt
      901 ttgggaattg ctttacttat ctagcagatg gtcaagcagg ggctttcttt gaaacacacc
      961 aaaaatattt ggatattcat ttagttttgg aaaacgaaga agccatggct gttacatcgc
     1021 cggaaaatgt aagcgttacc caagaatatg atgaagagaa agatattgaa ttatacacag
     1081 ggaaagtgga acagttggtt catttgagag ctggtgaatg cctcatcact tttccagaag
     1141 atttacatca acccaaggtt cgtataaatg atgaacctgt gaaaaaagtt gtctttaaag
     1201 ttgcgatttc ttaatgtaga aagagaagaa cgatgaaaaa aatgagaaag tttttatgtc
     1261 tagctggaat tgcgctagcg gctgttgcct tggtagcttg ttcaggaaaa aaagaagcta
     1321 caactagtac tgaaccacca acagaattat ctggtgagat tacaatgtgg cactccttta
     1381 ctcaaggacc ccgtttagaa agtattcaaa aatcagcaga tgctttcatg caaaagcatc
     1441 caaaaacgaa aatcaagatt gaaacatttt cttggaatga cttctatact aaatggacta
     1501 caggtttagc aaatggaaat gtgccagata tcagtacagc tcttcctaac caagtaatgg
     1561 aaatggtcaa ctcagatgct ttggttccgc taaatgattc tatcaagcgt attggacaag
     1621 ataaatttaa cgaaactgcc ttaaatgaag caaaaatcgg agatgattac tactctgttc
     1681 ctctttattc acatgcacaa gtcatgtggg ttagaacaga tttgttaaaa gaacataata
     1741 ttgaggttcc taaaacttgg gatcaactct atgaagcttc taaaaaattg aaagaagctg
     1801 gagtttatgg cttgtctgtt ccgtttggaa caaatgactt aatggcaaca cgtttcttga
     1861 acttctacgt acgtagtggt ggaggaagcc tcttaacaaa agatcttaaa gcagacttga
     1921 caagccaact tgctcaagat ggtattaaat actgggttaa attgtataaa gaaatctcac
     1981 ctcaagattc tttgaacttt aatgtccttc aacaagctac cttgttctat caaggaaaaa
     2041 cagcatttga ctttaactct ggcttccata tcggaggaat taatgccaac agtcctcaat
     2101 tgattgattc gattgatgct tatcctattc caaaaatcaa agagtctgat aacgaccaag
     2161 gaattgaaac ctcaaacatt ccaatggttg tttggaaaaa ttcaaaacat ccagaagttg
     2221 ctaaagcatt cttagaagca ctttataatg aagaagacta cgttaaattc cttgattcaa
     2281 ctccagtagg tatgttgcca actattaagg ggattagcga ttctgcagcc tataaagaaa
     2341 atgaaactcg taagaagttt aaacatgctg aagaagtaat tactgaagct gttaaaaaag
     2401 gtactgctat tggttatgaa aatggaccaa gtgtacaagc tggtatgttg actaaccaac
     2461 acattattga acaaatgttc caagatatca ttacaaatgg aacagatcct atgaaagcag
     2521 caaaagaagc agaaaaacaa ttaaacgatt tatttgaggc tgttcagtag atgtaaaaga
     2581 ctagaaaata ggtgggctag tgagctgaaa agctctagcc caatcttgta aaagaaggga
     2641 gaaggagaat ggttaaagaa cgtaatttaa ctcgctggat atttgttttg ccagctatga
     2701 ttatcgtagg attactcttt gtttatccgt ttttctcgag tattttttat agctttacca
     2761 ataagcattt gattatgcct aattataaat ttattggttt ggctaactat aaagctgtgc
     2821 tatcagatcc caacttcttt aatgcgttct ttaattcaat taagtggacc gttttctcat
     2881 tagttggtca agttttagta gggtttgtat tggctttagc tcttcacaga gtacgccact
     2941 tcaagaaatt atataggacc ttattgattg ttccttgggc atttcctacc atcgtcattg
     3001 ccttttcttg gcagtggatt ctaaacgggg tttatggcta cttacctaat ctaatcgtaa
     3061 aattaggttt aatggaacat acacctgcat ttttgacaga tagtacatgg gcattcctat
     3121 gtttggtgtt tatcaacatt tggtttggag caccaatgat tatggttaat gtgctttcag
     3181 ctttgcaaac agtaccagaa gaacaatttg aggctgctaa gatagatggt gcttcaagtt
     3241 ggcaggtgtt caagtttatc gtctttccac atattaaagt agttgtagga cttctagttg
     3301 ttttgagaac tgtatggatc tttaataact ttgacattat ctacctcatt actggtggtg
     3361 gaccagccaa tgctacaacg acgcttccaa tttttgctta caacctgggc tggggaacta
     3421 aattgttggg tcgtgcttca gcagttacag tattgctctt tatcttcttg gtggcgattt
     3481 gctttatcta ctttgctatc atcagtaagt gggaaaagga gagtagaaaa taatgaagaa
     3541 gaaatccggt atttatttag atattctctc acatgtactt ttagttggtt cgaccatcgt
     3601 tgcagttttc ccattggtat ggattatcat atcttctgtc aaagggaaag gggaattaac
     3661 tcagtatcca acacgatttt ggcctgaaca gtttacatta gattatttca ctcatgttat
     3721 caacgatttg cacttcattg ataacattcg aaacagttta atcattgcct tggctacaac
     3781 cctcattgcg attattattt ctgctatggc agcctatggt attgttcgat tctttcctaa
     3841 attgggagca atcatgtcga gactactcgt cattacctac attttcccac caattttgtt
     3901 agcaattccc tattcaattg ccattgctaa agttgggtta acaaatagtt tatttggctt
     3961 gatgatggtt tatctatctt ttagtgttcc atatgcagtt tggctcttag ttggattttt
     4021 ccaaacagtt ccaattggaa ttgaagaagc ggctagaatt gatggtgcaa ataaatttgt
     4081 tacgttttat aaagttgtgc taccgattgt agcaccaggt attgtagcaa cagctattta
     4141 tacatttatc aatgcttgga atgaattcct gtatgccttg attttgatta acaatacagg
     4201 aaagatgaca gtagcagtag cccttcgttc acttaatggt tcagaaatac tagactgggg
     4261 agatatgatg gcagcgtctg ttattgtagt tcttccatca attattttct tctctatcat
     4321 ccaaaataag attgcaagtg gattatcaga aggatctgtg aagtagacga aagaaggaaa
     4381 aaaatgaata aaagaggtct ttattcaaaa ctaggaattt ccgttgtagg cattagtctt
     4441 ttaatgggag tccccacttt gattcatgcg aatgaattaa actatggtca actgtccata
     4501 tctcctattt ttcaaggagg ctcatatcaa ctgaacaata agagtataga tatcagccct
     4561 ttgttattag ataaattgtc tggagagagt cagacagtag taatgaaatt taaagcagat
     4621 aaaccaaact ctcttcaagc tttgtttggc ctatctaata gtaaagcagg ctttaaaaat
     4681 aattactttt caattttcat gagagattct ggtgagatag gtgtagaaat aagagacgcc
     4741 caaaagggaa taaattattt attttctaga ccagcttcat tatggggaaa gcataaagga
     4801 caggcagttg aaaatacact agtatttgta tctgattcta aagataaaac atacacaatg
     4861 tatgttaatg gaatagaagt gttctctgaa acagttgata catttttgcc aatttcaaat
     4921 ataaatggta tagataaggc aacactagga gctgttaatc gtgaaggcaa ggaacattac
     4981 ctcgcaaaag gaagtattga tgaaatcagt ctatttaaca aagcaattag tgatcaggaa
     5041 gtttcaaata ttcccttgtc aaatccattt cagttaattt tccaatcagg agattctact
     5101 caagctaact attttagaat accgacacta tatacattaa gtagtggaag agttctatca
     5161 agtattgatg cacgttatgg tgggactcat gattctaaaa gtaagattaa tattgccact
     5221 tcttatagtg acgataatgg gaaaacgtgg agtgagccaa tttttgctat gaagtttaat
     5281 gactatgagg agcagttagt ttactggcca cgagataata aattaaagaa tagtcaaatt
     5341 agtggaagtg cttcattcat agattcatcc attgttgaag ataaaaaatc tgggaaaacg
     5401 atattactag ctgatgttat gcctgcgggt attggaaata ataatgcaaa taaagccgac
     5461 tcaggtttta aagaaataaa tggccattat tatttaaaac taaagaagaa tggagataac
     5521 gatttccgtt atacagttag agaaaatggt gtcgtttatg atgaaacaac taataaacct
     5581 acaaattata ctataaatga taagtatgaa gttttggagg gaggaaagtc tttaacagtc
     5641 gaacaatatt cggttgattt tgatagtggc tctttaagag aaaggcataa tggaaaacag
     5701 gttcctatga atgttttcta caaagattcg ttatttaaag tgactcctac taattatata
     5761 gcaatgacaa ctagtcagaa tagaggagag agttgggaac aatttaagtt gttgcctccg
     5821 ttcttaggag aaaaacataa tggaacttac ttgtgtcctg gacaaggttt agcattaaaa
     5881 tcaagtaaca gattgatttt tgcaacatat actagtggag aactaaccta tctcatttct
     5941 gatgatagtg gtcaaacatg gaagaaatcc tcagcttcaa ttccgtttaa aaatgcaaca
     6001 gcagaagcac aaatggttga actgagagat ggtgtgatta gaacattctt tagaaccact
     6061 acaggtaaga tagcttatat gactagtaga gattctggag aaacatggtc ggaagtttcg
     6121 tatattgatg gaatccaaca aacttcatat ggcacacaag tatctgcaat taaatactct
     6181 caattaattg atggaaaaga agcagtcatt ttgagtacac caaattctag aggtggccgt
     6241 aagggaggtc aattagttgt cggtttagtc aataaagaag atgatagtat tgattggaaa
     6301 taccactatg atattgattt gccttcgtat ggttatgcct attctgcgat tacagaattg
     6361 ccaaatcatc acataggtgt actgtttgaa aaatatgatt cgtggtcgag aaatgaattg
     6421 catttaagca atgtagttca gtatatagat ttggaaatta atgatttaac aaaataaagg
     6481 agaaaaacat ggttaaatac ggtgttgttg gagcagggta ttttggagct gaattggctc
     6541 gctatatgca aaagaatgat ggagcagaga ttactcttct ctatgatcca gataatgcag
     6601 aggcgattgc agaagaattg ggagcaaaag tagcaagttc cttagatgag ttggtttcta
     6661 gcgatgaagt agattgtgtt atcgtcgcaa ctccaaataa tcttcataag gaaccggtta
     6721 ttaaggctgc acagcatggt aaaaatgttt tctgtgaaaa accaattgcg ctttcttatc
     6781 aagattgtcg cgagatggta gatgcgtgta aagaaaacaa tgtaaccttt atggcaggac
     6841 atattatgaa tttctttaat ggtgttcatc atgcaaaaga actcattaat caaggagtta
     6901 tcggagacgt tctatattgt catacagctc gtaatggttg ggaagaacaa caaccgtcag
     6961 tatcatggaa aaaaattcgt gaaaaatcag gtggtcactt gtatcaccac atccatgaat
     7021 tggattgcgt tcaattcctt atggggggca tgcctgaaac tgtaaccatg acaggtggaa
     7081 atgtggccca tgaaggtgaa catttcggtg atgaagatga tatgattttt gtcaatatgg
     7141 aattttctaa taagcgtttt gccttgttag aatggggttc agcttatcgt tggggtgaac
     7201 attatgtctt aatccaagga agcaaaggtg ccatccgctt agacttattc aactgtaaag
     7261 gaactcttaa gctagatggg caagaaagct atttcttgat tcacgaatcg caagaagaag
     7321 atgatgatcg gactcgtatc tatcatagta cagagatgga tggagcaatt gcttatggta
     7381 aaccaggtaa acgtactcca ttatggctat catctgtcat tgataaagaa atgcgctatc
     7441 tgcatgagat tatggaagga gctccagtat cagaagaatt tgcaaaactt ttgacaggtg
     7501 aagctgccct agaagcaatt gctactgcag atgcttgtac ccagtctatg tttgaagatc
     7561 gcaaagtaaa attgtcagaa attgtaaaat aaattttggt attctcctat tataggtcga
     7621 cttgctcctc tgaaagtact tttagaggag ctgtttgact ttgctagttt ttgaaactga
     7681 aatctattat actacaaact attgaaagcg ttttaatttt aaggtataat aatctcatag
     7741 aaataaagaa aaggaggaaa gaggatgcca cagattagca aagaagcctt gattgagcaa
     7801 atcaaagatg gaatcatcgt ttcttgtcag gctcttcctc atgaaccgct ttatacagaa
     7861 gcgggagggg tgattccctt gctggtcaaa gcggctgagc aaggtggagc agtcggtatc
     7921 cgagcaaaca gtgttcgcga tatcaaggaa attaaggaag tcactaaact tccaatcatt
     7981 gggattatca aacgtgatta tccacctcag gaacccttca tcacggctac tatgaaagaa
     8041 gttgatgaat tggcagaact ggacatcgag gtgattgctc tggattgtac caagcgtgaa
     8101 cgctacgatg gtttggaaat tcaagagttc attcgtcagg ttaaggagaa atatcctaat
     8161 cagcttttga tggctgatac tagtatcttc gaagaagggc tagcagctgt agaagcagga
     8221 attgactttg tcggaacaac cttatcaggc tacacatcct acagtccaaa agtagacggt
     8281 ccagattttg aattgattaa gaaactctgt gatgctggtg tagatgtcat tgcagaagga
     8341 aaaattcata caccagaaca agccaaacaa atccttgaat atggagtgcg aggcatcgtt
     8401 gttggtggcg ccattactag accaaaagag attacagaac gcttcgttgc tagtcttaaa
     8461 taagatgtga gggggagttt tatgtttaaa gttttacaaa aagttggaaa agcttttatg
     8521 ttacctatag ctatacttcc tgcagcaggt ctacttttgg ggattggtgg tgcactttca
     8581 aacccaacca cgatagcaac ttatccaata ctagacaata gtatttttca atcgatattc
     8641 caagtaatga gctctgcagg agaggttgta ttcagtaatt tgtcactact tctctgtgtg
     8701 ggattatgta ttggcttagc gaaacgagat aaaggaaccg ctgcgttagc aggagtaact
     8761 ggttacttag ttatgactgc aacgatcaaa gctttggtaa aactttttat ggcagaagga
     8821 tctgcaattg atactggagt tattggagca ttagctgtcg gaatagttgc cgtatatttg
     8881 cacaaccgat ataacaatat tcaattacct tccgctttag gattctttgg aggttcacgc
     8941 ttcgttccta ttgttacatc gttctcttct atcttgattg gctttgtctt ctttgttatt
     9001 tggccacctt tccaacaact tcttgtttct acaggtggat atatttctca ggcgggtcca
     9061 attggaactt ttctatatgg atttttaatg agactttctg gagcagtagg cttacatcat
     9121 ataatttacc ctatgttttg gtatactgaa cttggtggtg ttgaaactat tgcaggacaa
     9181 acagtggttg gagctcaaaa aatatttttt gctcaattag ccgatccggc ccattctgga
     9241 ttatttacag aaggaacaag gttttttgca ggtcgtttct caacaatgat gttcggttta
     9301 ccggctgcct gtttagcgat gtaccatagt gttcctaaaa atcgtcgtaa aaaatacgcg
     9361 ggtttgtttt ttggagttgc tttaacatct tttattaccg gtattacaga accaattgaa
     9421 tttatgtttc tattcgtcag tccggttcta tatgttgttc acgcattcct tgatggtgtt
     9481 agcttcttta ttgcagacgt cttaaatatt tcaataggaa acacattttc aggaggtgta
     9541 atcgatttca ctttatttgg aattttgcag gggaacgcta agacgaattg ggttcttcag
     9601 attccaattg gacttatttg gagtgttttg tattatatta tttttagatg gttcattact
     9661 caattcaatg ttctaacgcc aggacgagga gaagaagtag attctaaaga aatttctgaa
     9721 tccgcagatt caacttcaaa tactgcagat tatttaaaac aggatagcct acaaattatc
     9781 agagccttgg gtggatcaaa taatatagaa gatgtagatg cttgtgtgac acgtttacgt
     9841 gtagctgtaa aagaagttaa tcaagttgat aaagcacttt taaaacaaat tggtgcagtt
     9901 gatgtcttag aagtgaaggg tggcattcaa gcaatctatg gagcaaaagc aatcttatat
     9961 aaaaatagta ttaatgaaat tttaggtgta gatgattaag tacttactga cttaataaaa
    10021 aacagaggag agtgatggat gagtaggatg aaatgaaatc gcatacaaga aataaagaac
    10081 tcattatcca agttggatac gcttattaca taggagaata caaatgaaat ttagaaaatt
    10141 agcttgtaca gtacttgcgg gtgctgcggt tcttggtctt gctgcttgtg gcaattctgg
    10201 cggaagtaaa gatgctgcca aatcaggtgg tgacggtgcc aaaacagaaa tcacttggtg
    10261 ggcattccca gtatttaccc aagaaaaaac tggtgacggt gttggaactt atgaaaaatc
    10321 aatcatcgaa gcgtttgaaa aagcaaaccc agatataaaa gtgaaattgg aaaccatcga
    10381 cttcaagtca ggtcctgaaa aaatcacaac agccatcgaa gcaggaacag ctccagacgt
    10441 actctttgat gcaccaggac gtatcatcca atacggtaaa aacggtaaat tggctgagtt
    10501 gaatgacctc ttcacagatg aatttgttaa agatgtcaac aatgaaaaca tcgtacaagc
    10561 aagtaaagct ggagacaagg cttatatgta tccgattagt tctgccccat tctacatggc
    10621 aatgaacaag aaaatgttag aagatgctgg agtagcaaac cttgtaaaag aaggttggac
    10681 aactgatgat tttgaaaaag tattgaaagc acttaaagac aagggttaca caccaggttc
    10741 attgttcagt tctggtcaag ggggagacca aggaacacgt gcctttatct ctaaccttta
    10801 tagcggttct gtaacagatg aaaaagttag caaatataca actgatgatc ctaaattcgt
    10861 caaaggtctt gaaaaagcaa ctagctggat taaagacaat ttgatcaata atggttcaca
    10921 atttgacggt ggggcagata tccaaaactt tgccaatggt caaacatctt acacaatcct
    10981 ttgggcacca gctcaaaatg gtatccaagc taaactttta gaagcaagta aggtagaagt
    11041 ggtagaagta ccattcccat cagacgaagg taagccagct cttgaatacc ttgtaaacgg
    11101 gtttgcagta ttcaacaata aagacgacaa gaaagtcgct gcatctaaga aattcatcca
    11161 gtttatcgca gatgacaagg agtggggacc taaagacgta gttcgtacag gtgctttccc
    11221 agtccgtact tcatttggaa aactttatga agacaaacgc atggaaacaa tcagcggctg
    11281 gactcaatac tactcaccat actacaacac tattgatgga tttgctgaaa tgagaacact
    11341 ttggttccca atgttgcaat ctgtatcaaa tggtgacgaa aaaccagcag atgctttgaa
    11401 agccttcact gaaaaagcga acgaaacaat caaaaaagct atgaaacaat agtccttagt
    11461 tattctataa aaagtagttt tttaaagaac ctaagagtgt ataccccctt ttccctctac
    11521 acagatagtg taagaaaagg gggcttttgt ttaaaatgta agaaactgtc acgaaattaa
    11581 aatgaagttc ttacataagc gaatcataaa aaatttcatt ttgattttaa aacagttcaa
    11641 gaaagtcaaa aaattattct atttgaaaga gaggtgccga ctgtgaaagt caataaaatc
    11701 cgtatgcggg aaacagtgat ttcctacgct ttcctagcac cagtattatt cttctttgtc
    11761 atctttgtgt tggctccgat ggtgatgggc ttcattacaa gtttctttaa ctactcaatg
    11821 actaaatttg agtttgtagg cttggataac tatatccgta tgtttaaaga tcctgtcttt
    11881 acaaaatctc tgattaacac agttattttg gttattggat ctgtaccagt tgttgttcta
    11941 ttctcactct ttgtagcatc tcagacctat catcaaaatg tcattgccag atccttctac
    12001 cgtttcgtct tcttccttcc tgttgtaacg ggtagtgttg ccgtgacagt tgtttggaaa
    12061 tggatttatg acccactatc agggattcta aactttgtcc ttaagtccag ccacatcatc
    12121 agccaaaaca tttcttggtt gggagataaa aactgggcat tgatggcgat tatgattatt
    12181 ctcttgacca cttcagttgg tcagcccatc atcctttata tcgctgccat ggggaatatt
    12241 gacaattcac tggttgaagc ggcgcgtgtt gatggtgcaa ctgagtttca agttttttgg
    12301 aagattaaat ggccaagcct tcttccaaca actctttata ttgcaatcat cacaacaatt
    12361 aactcattcc agtgttttgc cttgattcag cttttgacat ctggtggtcc aaactactca
    12421 acaagtacct tgatgtacta cctttacgaa aaagccttcc aattgacaga atacggctat
    12481 gccaacacaa ttggtgtctt cttggcagtc atgattgcta tcgtaagctt tgttcaattt
    12541 aaagtacttg gaaacgacgt agaatactaa agaaaggaga cagctatgca atctacagaa
    12601 aaaaaaccat taacagcctt tactgttatt tcaacaatca ttttgctctt gttgactgtg
    12661 ctgttcatct ttccattcta ctggattttg acaggggcat tcaaatcaca acctgataca
    12721 attgttattc ctcctcagtg gttccctaaa atgccaacca tggaaaactt ccaacaactc
    12781 atggtgcaga accctgcctt gcaatggatg tggaactcag tatttatctc attggtaacc
    12841 atgttcttag tctgtgcaac ctcatctcta gcaggttatg tattggctaa aaaacgtttc
    12901 tatggtcaac gcattctatt tgctatcttt atcgctgcta tggcgcttcc aaaacaagtt
    12961 gtccttgtac cattggtacg tatcgtcaac ttcatgggaa tccacgatac tctctgggca
    13021 gttatcttgc ctttgattgg atggccattc ggtgtcttcc tcatgaaaca gttcagtgaa
    13081 aatatcccta cagagttgct tgaatcagct aaaatcgacg gttgtggtga gattcgtacc
    13141 ttctggagtg tagccttccc gattgtgaaa ccagggtttg cagcccttgc aatctttacc
    13201 ttcatcaata cttggaatga ctacttcatg caattggtaa tgttgacttc acgtaacaat
    13261 ttgaccatct cacttggggt tgcgaccatg caggctgaaa tggcaaccaa ctatggtttg
    13321 attatggcag gagctgccct tgctgctgtt ccaatcgtca cagtcttcct agtcttccaa
    13381 aaatccttca cacagggtat tactatggga gcggtcaaag gataatactc tgagaaaatc
    13441 tcttcaaact acgtcagcgt caccttgcca tacttaagta ttgcctgcgg ttagcttcct
    13501 agtttgttct tcaattttca ttgagtatag gaaaatcaat ctatcaagat acagaagtat
    13561 attttataga tttagagaat atagaggtta taagtgtcta caaaatggag ggtatgcagt
    13621 tactttatga agttttgtca gacacttata aacttaagaa tggttttagt taactatcag
    13681 aaacgaagga aagagtatga tttttgacga tttgaaaaac atcacctttt acaaagggat
    13741 tcatcccaat ttagacaagg ctatcgacta tctctaccaa catcgtaaag attcattcga
    13801 attaggaaag tatgagattg atggagataa agtctttcta gttgttcagg aaaatgtcct
    13861 caatcaagtt gagaataatc gatttgaaca ccataagaac tatgcagatt tgcatttgct
    13921 gatagaaggg catgaatatt cgagctacgg ttcacgtatc aaagacgagg cagtagcatt
    13981 cgacgaagcg agtgacattg gctttgttca ttgtcatgaa cactacccac tcttgttggg
    14041 ttatcacaat tttgcgattt tcttcccagg tgagccacat cagccaaatg gttatgcagg
    14101 catggaagaa aaggttcgaa aatatctctt taaaattttg attgattaaa aataggatga
    14161 attgtttttt tgtaaagctt tgataatact ctaccatgaa attgatcttt gtgaggtaga
    14221 gaaatgagaa taaaatattt aaaaattggt atcttctaag tatgctgcaa gagctagttt
    14281 cttagatgga caggggatta cagttgatga gatggcttgg ataattaggg gcattgtgac
    14341 tgcattgatt ggtagataca taaaattagg tacttatgca gttaagtatg gtattagtat
    14401 ggcgcgctcg atcttaagta gggcagctgc aactgcggca gcaagagtag gattattgac
    14461 taagattttt ggatggattt tacgaatagc tgtgctcgca gctgatgtat atggtaattt
    14521 tgccaacaat attgctgtag cttgggatgc acatgataaa atccctaaca atggtcgtat
    14581 aaacttttaa aatgcgagaa tgaaagcact ttgtattttt ttattgtata tgttagcttg
    14641 gacagtgctt gcaatgataa tccgtggagg gctagatgga tttgatgaac acacttggcg
    14701 taatatttta gctagtgcgt tgtcctcgct atacatacat tatatatcca tagatagaaa
    14761 aagaaaaaag tccaaaagaa aaaagaaaaa atagatttgt tcatggtagg gacttatgaa
    14821 agctttactg acaaaaaaga aaacagttta caaagaaaaa tgatggagga gcaaacatgg
    14881 cacaaaaagg agtaagcctt atcaaggcag catttgatac agataacttt ctcatgcgtt
    14941 ttagtgagaa agtcttggac atcgtgacag ccaatcttct ttttgtcgtc tcttgtttgc
    15001 ccatcgtgac gattggagtg gctaaaatca gcctctacga gaccatgttc gaagttaaga
    15061 agagcagacg ggtgcctgtt tttaaaatct atctaagatc tttcaagcaa aatctgaaac
    15121 taggtcttca gctgggttta atggagttag gaattgtgtt tcttaccctt tcagatctct
    15181 atcttttctg gggtcaaaca gctctgccct tccaattgct gaaagccatt tgtttaggta
    15241 ttctgatttt tcttactatc gtgatgctgg ctagttaccc tatcgcggca cgttatgacc
    15301 tatcttggaa agaaattctt caaaaaggat tgatgttggc tagttttaac tttccttggt
    15361 tcttcctcat gttagccatt cttgtcctca ttgtgatggt tctttatctg tccgccttca
    15421 gtctactctt aggtggctca gtcttcttac tttttgggtt tggactattg gtctttatcc
    15481 agactggatt gatggagaaa attttcgcaa aataccaata ggagccttat ttctgaaact
    15541 actttcaaac gctccaaacg ctattctata agcgagaaac taaaatctaa gtgtctataa
    15601 gatattgaaa gccttttctg taaagtgtat actaaagaag taaagaaaaa tctgctttag
    15661 cagaaaataa aaataatagg agaaaatcta tgtcagattt gaaaaaatac gaaggtgtca
    15721 ttccagcctt ctacgcatgt tatgatgatc aaggagaagt aagcccagaa cgtacgcgtg
    15781 ccttggttca atacttcatt gataaaggtg ttcaaggtct ttatgtcaat ggttcttctg
    15841 gtgaatgtat ctaccaaagc gttgaagatc gcaagttgat tttggaagaa gtcatggcgg
    15901 tagccaaagg taaattgacc attattgctc atgttgcctg caacaatact aaagacagta
    15961 tggaacttgc tcgccatgct gaaagcttgg gagtagatgc tattgcaacg attccaccaa
    16021 tttatttccg cttgccagaa tactcagttg ccaaatactg gaacgatatc agttctgcag
    16081 ctccaaacac agactacgtg atttacaaca ttcctcaatt ggcaggggtt gctttgactc
    16141 caagccttta cacagaaatg ttgaaaaatc ctcgtgttat cggtgttaag aactcttcta
    16201 tgccagttca agatatccaa acctttgtca gccttggtgg ggaagaccat atcgtcttta
    16261 atggtcctga tgagcagttc ctaggaggac gcctcatggg tgctagggct ggtatcggtg
    16321 gtacttatgg tgctatgcca gaactcttct tgaaactcaa tcagttgatt gcggataagg
    16381 acctagaaac agcgcgtgaa ttgcagtatg ctatcaacgc aatcattggt aaactcactt
    16441 ctgctcatgg aaatatgtac ggtgtcatta aagaagtctt gaaaatcaat gaagtcttga
    16501 atattggatc tgttcgttca ccattgacac cagtgactga agaagatcgt ccagttgtag
    16561 aagcggctgc tgccttgatt cgtgaaacca aggagcgctt cctctaatct aaaaggaggt
    16621 atttatgaca tactacgttg caattgatat cggtggaacc aacatcaagt atggtttggt
    16681 tgatcaagag gggcaacttc ttgaatcgca tgaaatgcca actgaggcgc ataagggtgg
    16741 acctcatatc ttacaaaaga ccaaagatat cgtagctagt tatttagaaa aaggcccagt
    16801 agcaggtgtt gccatatctt ctgctgggat ggtggatccg gataagggtg agattttcta
    16861 tgctgggcct caaatcccta actacgcagg cacccagttc aaaaaggaaa tcgaagaaag
    16921 ctttactatt ccttgtgaga ttgaaaatga tgtcaactgt gcaggtcttg ctgaggcagt
    16981 atctggttca ggcaagggag caagtgtgac actttgcttg accattggaa ccggtatcgg
    17041 tggttgcttg attatggata ggaaagtctt ccatggtttt agtaattcag cctgtgaagt
    17101 cgggtatatg catatgcagg atggagcttt tcaggatctc gcttctacaa cagctttagt
    17161 gaaatatgta gctgaagccc atggagaaga tgttgatcag tggaatggcc gacgtatctt
    17221 taaggaagct actgaaggaa acaaaatctg catggaaggt attgaccgta tggttgacta
    17281 tctaggaaaa ggtctggcaa atatttgtta tgtggccaat ccagaagtgg ttattcttgg
    17341 tggtggtatc atggggcaag aggctatcct caaacctaag atccgcacag ccttgaaaga
    17401 ggcattggta ccaagtttag cagaaaaaac acgattagaa tttgcccatc accaaaatac
    17461 agcagggatg ttgggtgcat attatcattt taagacaaaa caatcctagt ttggctcagc
    17521 caaactagga ttttcttaca cgtttttgtc tacgatagcc gttgagtttt ttattttccc
    17581 agtagctatt aaagattttt tccttgcttt cgcgattgat ttccaaaaag taggcataaa
    17641 tcaaatcgat aaagaagagc ataggaagtt gagcggatat tcgttggata taggagggtt
    17701 ggctgtgggt ggctacaaga acagtctctg tataggtctg gctatcttta ttgggaacac
    17761 ttgtaaagag tacagtcttt gcccccatct ccttagcatc taatagacta tctaaaatag
    17821 aaggagttga gcctgaaagt gagaagccca gtactagaca attttcatcc atgatgctgg
    17881 ttgtccaggc aaagccgtct tggtctgtca aagcttcgca gaccacacct agtcgcataa
    17941 aacgtaattt catttcacgg gcgacgaggc cagaactccc tgttccaaag aagtagatac
    18001 gctcagcatc ttcgattagc tgggcaattc gttctagttg gatttcgtca atcaagtctt
    18061 gtgtttgttc cctcatattg ctataacttc tgaggactcg tttggtcagt ggactgtgct
    18121 tggagacttg gttggcttga ttttctgcct gatgttggta ttggaaaata aattctcggt
    18181 agccagtaaa gccacacttt ttagcaaagc gggtcaaagc agcttgagaa atatgtaatt
    18241 tttgggtgac ttgttgagaa gataaatcat ctgtaatcgt ttcagcttgc aaaaaatagc
    18301 gagcgatttc ttgttctagg tctgtcattt cttcaaaatg tgaatcaatg atagttgcga
    18361 tatctggttt gtccataggg aaagctcctt tacatgggtc atactggaag actagatcag
    18421 ggaatagtca cacttcatta taacacataa tataaggata gataaataaa aacgcatctc
    18481 tgttttaaaa acgaaaaaat cgaaaaagct tctctctttt ccataatttt ctactcaaat
    18541 tgtggtacaa ttaagagtaa gattttaagt tagaaatgag actgatttgt atgagaaaat
    18601 ttaacagcca ttcgattccg attcggctta atttattgtt ttcaatcgtc attttactct
    18661 ttatgaccat tattggtcgt ttgttgtata tgcaggtttt gaacaaggat ttttacgaaa
    18721 aaaagctagc ttcagctagt cagaccaaga ttacaagcag ttcagcccgt ggggaaattt
    18781 atgatgctag tggaaaacct ttggtagaaa atacgttaaa gcaggttgtt tcctttacgc
    18841 gtagcaataa aatgacggct acagacttaa aagaaacagc taaaaagtta ctgacttatg
    18901 tgagcatcag ttctccaaat ttgacagaac gccagctggc ggattactat ttggctgatc
    18961 ctgaaatcta taaaaaaata gtggaagctc tcccaagtga gaaacgcttg gattcagatg
    19021 gcaatcgtct atccgaatca gaactgtata acaatgcggt cgatagtgta caaacgagtc
    19081 aactaaacta tacagaggat gaaaagaaag aaatctatct ttttagtcag ttaaatgctg
    19141 ttggaaactt tgcgacagga accattgcga cagatcctct aaatgattct caggtggctg
    19201 ttattgcctc tatttcaaag gagatgcctg gcattagtat ttctacttct tgggatagaa
    19261 aggttttgga aacttccctt tcttctatag ttgggagtgt atccagtgaa aaagctggtc
    19321 tcccagcgga agaagcagaa gcctatctta aaaaaggcta ttctctaaat gatcgtgtag
    19381 gaacctccta tttggaaaag caatatgaag agaccttaca aggaaaacgc tcggtaaaag
    19441 aaatccatct ggataaatat ggcaatatgg aaagcgtgga tacaattgag gaaggtagta
    19501 agggaaacaa tatcaaactg accattgatt tggccttcca agatagcgtg gatgctttac
    19561 tgaaaagtta tttcaattcc gagctagaaa atggtggagc caagtattct gaaggtgtct
    19621 atgcagtcgc ccttaaccca aaaacaggtg cggttttgtc tatgtcaggg attaaacatg
    19681 acttgaaaac gggagagttg acgcctgatt ccttgggaac ggtaaccaat gtctttgttc
    19741 caggttcggt tgtcaaggcg gcgaccatca gctcaggttg ggaaaatgga gtcttgtcag
    19801 gaaaccagac cttgacagac cagtccattg tcttccaagg ttcagctccc atcaattctt
    19861 ggtatactca ggcttacggt tcattcccta tcacagcggt ccaagctctg gagtattcat
    19921 caaataccta tatggtccaa acagccttag gtcttatggg gcaaacctat caacccaata
    19981 tgtttgtcgg caccagcaat ctagagtctg ctatggagaa actgcgttca acctttggcg
    20041 aatatggctt gggtactgcg acaggaattg acctaccaga tgaatctact ggatttgttc
    20101 ccaaagagta tagctttgct aattacatta ctaatgcctt tgggcagttt gataactata
    20161 cgccgatgca gttggctcag tatgtagcaa ctattgcaaa taatggtgtt cgtgtggctc
    20221 ctcgtattgt tgaaggcatt tatggtaata atgataaggg aggactgggt gacttgattc
    20281 agcaactgca accgacagag atgaataagg tcaatatatc cgactccgat atgagcatct
    20341 tgcaccaagg tttttatcag gttgcccatg gtactagtgg attgacaact ggacgtgcct
    20401 tttcaaatgg cgccttggta tccattagcg gaaaaacagg tacagccgaa agctatgtgg
    20461 cagatggtca gcaagcaacc aataccaatg cggtggccta tgccccatct gataatcccc
    20521 aaatcgctgt tgcagtggtc tttcctcata ataccaatct aacaaatggt gtaggacctt
    20581 ccattgcgcg tgacattatc aatctgtatc aaaaatacca tccaatgaac tagaaaggaa
    20641 attatgcttt atccaacacc tattgccaag ttgattgaca gttattctaa gttaccaggt
    20701 atcgggatta agacggctac gcgtctggcc ttttatacga ttgggatgtc tgctgatgat
    20761 gtcaatgaat ttgcaaaaaa tctcctttct gctaagagag aattgacata ttgttctatt
    20821 tgtggacgtt tgacagacga cgatccttgt tctatctgta ctgatccgac tcgtgaccag
    20881 acaacaattt tagttcttga ggatagtaga gatgtggcag ccatggaaaa tatccaagaa
    20941 taccatggac tctatcatgt ccttcatggc ctcatttctc ctatgaatgg tatcagtccg
    21001 gacgatatca atctcaagag ccttatgact cgtcttatgg atagtgaagt ttcagaagtg
    21061 attgtggcga ctaatgctac agcggatggt gaagcgactt ccatgtatct ttcacgtttg
    21121 ctcaagccgg ctggtatcaa ggttacgcgt ctagcacgag gtctcgctgt gggagcggac
    21181 attgagtatg cggacgaagt gacactctta cgagccattg aaaatcggac agagttgtaa
    21241 gtgtaggcaa atttacgaac ttcattcatt tataaaaaat caaagaggct gaaaatcgtt
    21301 cctatcggcc tctttttgta tagtgtgatg agtaggatca ggttcaagtt ttaaaaaacc
    21361 aagcaaatat gatatactaa agagcgagta ttctagtaga attaggacaa ataatatgaa
    21421 acaaacgatt attcttttat atggtggacg gagtgcggaa cgcgaagtct ctgtcctttc
    21481 agctgagagt gtcatgcgtg cggtcaatta cgaccgtttc acagtcaaga ctttctttat
    21541 cagtcagtca ggtgacttta tcaaaacaca ggaatttagt catgctccgg ggcaagaaga
    21601 ccgtctcatg accaatgaaa ccattgattg ggataagaaa gttgcaccaa gtgctatcta
    21661 cgaagaaggt gcagtggtct ttccagtcct tcacgggcca atgggagaag atggctctgt
    21721 tcaaggattc ttggaagttt tgaaaatgcc ttacgttggt tgcaacattt tgtcatcaag
    21781 tcttgccatg gataaaatca cgactaagcg tgttctggaa tctgctggta ttgcccaagt
    21841 tccttatgtg gctatcgttg aaggcgatga tgtgactgct aaaatcgctg aagtggaaga
    21901 aaaattggct tatccagtct tcactaagcc gtcaaacatg gggtctagtg tcggtatttc
    21961 taagtctgaa aaccaagaag aactccgtca agccttaaaa cttgccttcc gatatgacag
    22021 ccgtgtcttg gttgagcaag gagtgaatgc ccgtgaaatt gaggttggcc tcttgggtaa
    22081 ctacgatgtc aagagcacgc tacctggaga agttgtcaag gacgttgcct tttatgacta
    22141 cgatgccaag tatattgata acaagattac tatggatatt cctgccaaaa tcagtgatga
    22201 tgtggtggct gtcatgcgtc aaaatgcaga aacagccttc cgtgccattg gtggccttgg
    22261 tctatctcgt tgcgatttct tctatacaga taagggagag atttttctca acgagctcaa
    22321 taccatgcca ggttttaccc agtggtctat gtacccacta ctttgggaca atatggggat
    22381 cagctaccca gaactaatcg agcgtttggt tgaccttgcc aaggaaagtt ttgacaagcg
    22441 cgaagcgcat ttgatataaa atgaaagaga gggtagaagc cagaaccatc actgcacggt
    22501 gactagagtt ctcggacttc agcccttttt aaaggagtag aaatgaaatt aacaatccat
    22561 gaaattgccc aagttgttgg agccaaaaat gatatcagta tctttgagga cacccagtta
    22621 gaaaaagctg agtttgatag tcgtttgatt ggaactggag atttatttgt gccacttaaa
    22681 ggtgcgcgtg atggccatga ctttattaaa acagcctttg aaaatggtgc agcagtaacc
    22741 ttgtctgaga aagaggtctc aaatcatcct tacattctag tagatgatgt tttgacagcc
    22801 tttcaatccc tagcatccta ctatcttgaa aaaacgactg ttgatgtctt tgctgttaca
    22861 ggttcaaatg gcaagacaac gactaaggat atgttggcgc atttactgtc aacaagatac
    22921 aagacctaca aaacacaagg caattacaat aatgagattg gccttcctta cacagttctc
    22981 cacatgcctg aaggaacaga aaagttggtc ttggagatgg ggcaggacca cttgggagat
    23041 attcatctct tgtctgaatt ggctcgtcca aaaacagcca tcgtgacctt ggttggagaa
    23101 gctcatttgg cctttttcaa agatcgttct gagattgcta aaggaaaaat gcaaattgca
    23161 gacggaatgg cttcaggttc cttgctttta gcgccggctg accctatcgt agaggactat
    23221 ttgccaactg ataaaaaggt ggtccgtttt gggcaagggg cagagttgga aatcacagac
    23281 ttggttgagc gcaaagatag tctaaccttc aaggccaatt tcttagagca agcccttgat
    23341 ttgccagtaa ctggtaagta caatgctacc aatgctatga ttgcatccta tgttgcccta
    23401 caagaaggag tttcagagga gcaaattcat caggccttcc aaggtcttga attgacgcgt
    23461 aatcgtactg agtggaagaa agcagccaat ggagcagata tcctgtcaga cgtatataat
    23521 gccaatccaa ctgctatgaa gctgatttta gagactttct ctgccattcc agccaatgaa
    23581 ggtggcaaga aaattgcagt gttggcggat atgaaggagc ttggtgacca gtctattcaa
    23641 ctccataacc agatgatttt gagcctttct ccagatgtgc ttgataccgt tattttctat
    23701 ggagaagaca ttgctgaatt agcccaattg gccagtcaaa tgttcccaat aggccacgtt
    23761 tactacttca agaaaacaga agaccaagac caatttgaag acctagtcaa gcaggtcaag
    23821 gaaagcctca gtgccaatga tcaaatcttg ctcaagggct ctaactctat gaacctagcc
    23881 atgttggtag aaagtttaga aaatgaaacc aagtgatttt gttaagtatc tgcaaagaat
    23941 gattgccctt acagatactg gcttaacctt tacaaaagat ccttttgact gtgagcgcta
    24001 cgaggacttg cgaagtctgt tatctgaaat gttgaatcag ggatcagacc tggatgcaga
    24061 agaagtagca gaagtcttga aaccaacttc agcttatgcg actcccttaa tggacgtccg
    24121 tgcttggatt gttgaggatg agaagatttg tctggttagg ggacaaggag aggatagttg
    24181 ggctttgcca ggtggctttg gtgaagtcgg ctattctcca actgaaaata ttctcaagga
    24241 aattgaagaa gaaaccggtt ttaaagccaa agttgaaaga ctgctagctg tttttgatac
    24301 caatcgtttc caactacaga gcaaacaata tgcaaagttt gtttttgaat gtaagcttct
    24361 cgatggacaa ttccaagaaa atcaagaaat cgctgacctt caattttttg caattgacca
    24421 actgccgaat ttatctgaaa aacgcattac caaggagcaa atcgagattc tttggcaggt
    24481 ttatcaaggt cagagggagc aatatcttga ctaagaagat gattatcgta tttctaaatc
    24541 catttttgac aactagcatg gtataataat atgcaggaaa attttgaatt atgaggaaga
    24601 ctagatgaat ttatgggata ttttctttac gactcaggca accgagccgc ccaaatttga
    24661 ccttttttgg tatgttagcc tatttacgct cttagcctta accttttata cagcccatcg
    24721 ctatcgtgaa aagaaggttt accaacgatt tttccaaatc ttgcagactg ttcagttaat
    24781 ccttctttat ggttggtact gggtcaatca tatgccactg tcagaaagcc taccctttta
    24841 ccattgccgt atggctatgt ttgtggtact cttgcttcct ggtcagtcca aatataaaca
    24901 atactttgca ttattgggaa catttgggac attagcagcc tttgtttatc cagtgccaga
    24961 tgcttaccct tttccacata tcaccattct atcctttatc tttggtcatt tagcactctt
    25021 ggggaactct ctagtttatc tattgagaca gtataatgcg cgattgctgg atgtgaaggg
    25081 aatttttctc atgacctttg ccctaaatgc cttgattttt gtggtcaatt tggtgacagg
    25141 tggcgattac ggatttttga caaaaccgcc attggttggg gatcacggtc tagtagctaa
    25201 ttatttactt gtttcaattg tgctggtagc tactatcagt ttgactaaga aaatcttaga
    25261 attcttttta gctcaagaag cagaaaaaat gattgcaaag gaagcttaac acagagcttt
    25321 cttttttgct cttagagagt ttttacaagc agcttataaa ataagaattt ctgaatagac
    25381 aaactcaaaa aatggctggg aaatttagga aaaaagcaag cacgattaaa ttttttgtgt
    25441 tataatattt tgtgaatagc tatgcctatg tttagctatg gaataatacg aagtgcgaaa
    25501 cttggaagat agagaggaag cgatgtaatg gctagagaag gcttttttac aggtctagat
    25561 attggaacaa gctctgtcaa ggtgcttgtg gccgagcaga gaaatggtga attaaatgta
    25621 attggcgtga gtaatgccaa aagtaaaggt gtaaaggatg gaattattgt tgatattgat
    25681 gcagcagcaa ctgctatcaa gtcagccatt tcccaagcgg aagaaaaggc aggcatttcg
    25741 attaaatcag taaatgtcgg cttgcctggt aatcttttgc aggtagaacc aactcagggg
    25801 atgattccag taacatctga tactaaggaa attacggatc aagatgttga aaatgttgtc
    25861 aaatcagctt tgacaaagag tatgacacct gaccgtgaag tcattacctt tattcctgaa
    25921 gaatttattg tggatggttt ccaagggatt cgtgacccac gtggcatgat gggggttcgc
    25981 cttgaaatgc gtggtttgct ttatacagga cctcgtacta tcttgcacaa tttgcgtaag
    26041 acggttgagc gtgcaggtgt tcaggttgaa aatgttatca tttcaccact agcaatggtt
    26101 cagtctgttt tgaacgaagg ggaacgtgaa tttggtgcta cagtgattga tatgggggca
    26161 ggtcaaacga ctgtcgctac aatccgtaat caagaactcc agttcacaca tattctccaa
    26221 gaaggtggag attatgtaac taaagatatc tccaaggttt tgaaaacctc tcgcaaatta
    26281 gcggaaggct tgaaactgaa ttacggggaa gcctatccgc ctcttgcaag caaagaaacc
    26341 ttccaagtag aggttattgg agaagtagaa gcagtcgaag tgacggaagc ctacttgtca
    26401 gaaattattt ctgcacgaat caagcacatc cttgaacaaa tcaagcaaga attagataga
    26461 aggcgtctat tggacctccc tggtggtatt gtcttaatcg gtgggaatgc cattttacca
    26521 ggtatggttg agcttgctca ggaagtcttt ggcgtccgtg tcaagcttta tgttccaaat
    26581 caagttggta tccgtaatcc agcctttgcg catgtgatta gtttatcaga atttgcgggt
    26641 caattaacag aagttaatct tttggctcag ggagcgataa aaggtgagaa tgacttaagt
    26701 catcagccaa ttagttttgg tgggatgctg caaaaaacag ctcagtttgt acaatcaacg
    26761 cctgttcaac cagctcctgc tccagaagta gagtcggtgg cgcctacaga accaatggcg
    26821 gatttccaac aagcttcaca aaataaaccg aaattagcag atcgtttccg tggcttgatc
    26881 ggaagcatgt ttgacgaata aagaggaaaa ataaattatg acattttcat ttgatacagc
    26941 tgctgctcaa ggggcagtga ttaaagtaat tggtgtcggt ggaggtggtg gcaatgccat
    27001 caaccgtatg gtcgacgaag gtgttacagg cgtagaattt atcgcagcaa acacagatgt
    27061 acaagcattg agtagtacaa aagctgagac tgttattcag ttgggaccta aattgactcg
    27121 tggtttgggt gcaggaggtc aacctgaggt tggtcgtaaa gccgctgaag aaagcgaaga
    27181 aacattgacg gaagctatta gtggtgccga tatggtcttc atcactgctg gtatgggagg
    27241 aggctctgga actggagctg ctcctgttat tgctcgtatc gccaaagatt taggtgcgct
    27301 tacagttggt gttgtaacac gtccctttgg ttttgaagga agtaagcgtg gacaatttgc
    27361 tgtagaagga atcaatcaac ttcgtgagca tgtagacact ctattgatta tctcaaacaa
    27421 caatttgctt gaaattgttg ataagaaaac accgcttttg gaggctctta gcgaagcgga
    27481 taacgttctt cgtcaaggtg ttcaagggat taccgatttg attaccaatc caggattgat
    27541 taaccttgac tttgccgatg tgaaaacggt aatggcaaac aaagggaatg ctcttatggg
    27601 tattggtatc ggtagtggag aagaacgtgt ggtagaagcg gcacgtaagg caatctattc
    27661 accacttctt gaaacaacta ttgacggtgc tgaggatgtt atcgtcaacg ttactggtgg
    27721 tcttgactta accttgattg aggcagaaga ggcttcacaa attgtgaacc aggcagcagg
    27781 tcaaggagtg aacatctggc tcggtacttc aattgatgaa agtatgcgtg atgaaattcg
    27841 tgtaacagtt gttgcaacgg gtgttcgtca agaccgcgta gaaaaggttg tggctccaca
    27901 agctagatct gctactaact accgtgagac agtgaaacca gctcattcac atggctttga
    27961 tcgtcatttt gatatggcag aaacagttga attgccaaaa caaaatccac gtcgtttgga
    28021 accaactcag gcatctgctt ttggtgattg ggatcttcgc cgtgaatcga ttgttcgtac
    28081 aacagattca gtcgtttctc cagtcgagcg ctttgaagcc ccaatttcac aagatgaaga
    28141 tgaattggat acacctccat ttttcaaaaa tcgttaagta aatgaatgta aaagaaaata
    28201 cagaacttgt ttttcgagaa gttgcagagg ctagtctgag tgctcatcga gagagtggtt
    28261 cggtctctgt cattgcagtt accaagtatg tagatgtacc gacagcggaa gccttgcttc
    28321 cgctaggtgt ccatcatatc ggtgaaaatc gtgtagataa gtttctggaa aaatatgaag
    28381 ctttaaaaga tcgagatgtg acttggcatt tgattggtac cttgcaaaga cgtaaggtga
    28441 aagatatcat tcaatacgtt gattatttcc atgcattgga ctcagtaaag ctagcagggg
    28501 aaattcaaaa aagaagtgac cgagtcatca agtgtttcct tcaagtaaat atttctaaag
    28561 aagaaagcaa acacggtttt tcgagagagg aactgctgga aatcttgcca gagttagccg
    28621 gactagataa gattgaatat gttggtttaa tgacgatggc accttttgag gctagcagtg
    28681 agcagttgaa agagattttc aaggcggccc aagatttaca aagagaaatt caagagaaac
    28741 aaattccaaa tatacctatg accgagttaa gtatgggaat gagtcgtgat tataaagaag
    28801 cgattcaatt cggttccact tttgttcgta taggtacatc attttttaag taggagagaa
    28861 ccatgtcttt aaaagataga ttcgatagat ttatagatta ttttacggag gatgaggatt
    28921 caagtctccc ttatgaaaaa agagatgagc ctgtgtttac tccagtaaat tcttcacagg
    28981 aaccggctct cccaatgaat caaccttcac agtcggctgg tacaaaagag aacaatatca
    29041 ccagacttca tgcaagacaa caggaattgg caaatcagag tcagcgtgca acggataagg
    29101 tcattataga tgttcgttat cctagaaaat atgaggatgc aacagaaatt gttgatttat
    29161 tggcaggaaa cgaaagtatc ttgattgatt ttcagtatat gacagaggtg caggctcgtc
    29221 gttgtttgga ctatttggat ggagcttgtc atgttttagc tggaaatttg aaaaaggtag
    29281 cttctaccat gtatttgttg acaccagtga atgttattgt aaatgttgaa gatatccgtt
    29341 taccagatga agatcaacag ggtgagttcg gttttgatat gaagcgaaat agagtacgat
    29401 aatgattttt ttaattcgta tgatttataa tgcagtggat atttactccc tgattttggt
    29461 agccttcgct gtcatgtctt ggtttccagg tgcctacgaa tccagtttag gtcgttggat
    29521 tgtagcgttg gtgaaaccag tgcttgctcc cttgcaacgc ctgcctttac agatagcggg
    29581 tcttgattta tctgtttggg ttgcgattgt tttggttcga tttttaggag aaaacctagt
    29641 gcgttttctg gcgatgatag gatgaataaa gggatttatc agcatttctc catagaagat
    29701 cgtccatttc ttgacaaggg aatggaatgg ataaagaagg tagaagatag ctatgctcct
    29761 tttttaactc cttttatcaa tcctcatcag gagaagctat taaagatttt ggccaaaacc
    29821 tatggtcttg cttgtagcag tagtggggaa ttcgtctcga gtgagtatgt tcgagtttta
    29881 ttatacccag attatttcca accagagttt tcagattttg aaatatctct ccaggaaatt
    29941 gtgtattcca ataaatttga atatttaacg catgctaaga ttttagggac agtcatcaat
    30001 caattaggga ttgaacggaa actttttgga gatatcctag tagatgaaga acgggcgcag
    30061 attatgatta atcagcagtt tcttcttctc tttcaagatg gactaaagaa aattggtcgt
    30121 atacctgttt cgctggagga acgtcctttc accgagaaaa tagataagct agaacagtat
    30181 cgagaactgg atttatctgt gtctagtttt cgattagatg ttcttttatc aaatgttttg
    30241 aaactatcta ggaatcaagc aaaccagttg attgaaaaga aacttgtcca agtaaattat
    30301 catgtggtag acaaatcaga ttacactgtt caagttggag acttgattag tgtgagaaaa
    30361 tttggtcgct tgagattact tcaagataag ggacaaacga aaaaagagaa gaaaaaaata
    30421 accgtccagt tattattaag taagtgagga atagaatgcc aattacatca ttagaaataa
    30481 aggacaagac ttttggaact cgattcagag gttttgatcc agaagaagtc gatgaatttt
    30541 tagatattgt ggttcgtgat tacgaagatc ttgtgcgtgc gaatcatgat aaaaatttgc
    30601 gtattaagag tttagaagag cgtttgtctt actttgatga aataaaagat tcattgagcc
    30661 agtctgtatt gattgcccag gatacagctg agcgagtgaa acaggcggcg catgaacgtt
    30721 caaacaatat cattcatcaa gcagagcaag atgcgcaacg cttgttggaa gaagctaaat
    30781 ataaggcaaa cgagattctt cgtcaagcaa ctgataatgc taagaaagtc gctgttgaaa
    30841 cagaagaatt gaagaacaag agccgtgtct tccaccaacg tctcaaatct acaattgaga
    30901 gtcagttggc tattgttgaa tcttcagatt gggaagatat tctccgtcca acagctactt
    30961 atcttcaaac cagtgatgaa gcctttaaag aagtggttag cgaagtactt ggagaaccga
    31021 ttccagttcc aattgaagaa gaaccaattg atatgacacg tcagttctct caagcagaaa
    31081 tggaagaatt acaagctcgt attgaggtag ccgataaaga attgtctgaa tttgaagctc
    31141 agattaaaca ggaagtggaa gctccaactc ctgtagtgag tcctcaagtt gaagaagagc
    31201 ctctgctcat ccagttggcc caatgtatga agaaccagaa gtagctccag tgcatccgac
    31261 aggtccaaca ccagctacag aaactgttga ttcagcaccg ggatttgaag caccgcaaga
    31321 atctgttaca attttataag aaatattctg agaacaatat cttatcctta tattcccagc
    31381 gagcaggaga tggtgtgagt cctgcattcc ctatcgataa gattatcctc tcaaaaactc
    31441 aagtctgaat ctagtaagat ttgacgttcc ccacgttacg ggataagagg gagaaagact
    31501 aaaacttttt ccgaataaag gtggtaccac gattttcgtc ctttttggaa gtcgtggttt
    31561 ttaatttgtt attatttata aaggagatac catgaaactc aaagacaccc ttaatcttgg
    31621 gaaaactgaa ttcccaatgc gtgcaggcct tcctaccaaa gagccagttt ggcaaaagga
    31681 atgggaagat gcaaaacttt atcaacgtcg tcaagaattg aaccaaggaa aacctcattt
    31741 caccttgcat gatggccctc catacgctaa cggaaatatc cacgttggac atgctatgaa
    31801 caagatttca aaagatatta ttgttcgttc taagtctatg tcaggatttt acgcaccatt
    31861 tattcctggt tgggatactc atggtctgcc aatcgagcaa gtattgtcaa aacaaggtgt
    31921 caaacgtaaa gaaatggact tggttgagta cttgaaactt tgccgtgagt acgctctttc
    31981 tcaagtagat aaacaacgtg aagattttaa acgtttgggt gtttctggtg actgggaaaa
    32041 tccatatgtg accttgactc ctgactatga agcagctcaa attcgtgtat ttggtgagat
    32101 ggctaataag ggttatatct accgtggtgc caagccagtt tactggtcat ggtcatctga
    32161 gtcagccctt gctgaagcag agattgaata ccatgacttg gtttcaactt ccctttacta
    32221 tgccaacaag gtaaaagatg gcaaaggagt tctagataca gatacttata tcgttgtctg
    32281 gacaacgact ccatttacca tcacagcttc tcgtggtttg acggttggtg cagatattga
    32341 ttacgttttg gttcaacctg ctggtgaagc tcgtaagttt gtcgttgctg ctgaattatt
    32401 gactagcttg tctgagaaat ttggctgggc tgatgttcaa gttttggaaa cttaccgtgg
    32461 ccaagaactc aaccacatcg taacagaaca cccatgggat acagctgtag aagagttggt
    32521 aattcttggt gaccacgtta cgactgactc tggtacaggt attgtccata cagcccctgg
    32581 ttttggtgag gacgattaca atgttggtat tgctaataat cttgaagtcg cagtgactgt
    32641 tgatgaacgt ggtatcatga tgaagaatgc tggtcctgaa tttgaaggtc aattctatga
    32701 aaaggtagtt ccaactgtta ttgaaaaact tggtaacctc cttcttgccc aagaagaaat
    32761 ctctcactca tatccatttg actggcgtac taagaaacca atcatctggc gtgcagttcc
    32821 acaatggttt gcctcagttt ctaaattccg tcaagaaatc ttggacgaaa ttgaaaaagt
    32881 gaaattccac tcagaatggg gtaaagtccg tctttacaat atgatccgtg accgtggtga
    32941 ctgggttatc tctcgtcaac gtgcttgggg tgttccactt cctatcttct acgctgaaga
    33001 tggtacagct atcatggtag ctgaaactat tgaacacgta gctcaacttt ttgaagaaca
    33061 tggttcaagc atttggtggg aacgtgatgc caaagacctc ttgccagaag gatttactca
    33121 tccaggttca ccaaacggcg agttcaaaaa agaaactgat atcatggacg tttggtttga
    33181 ctcaggttca tcatggaatg gagtggtggt aaaccgtcct gaattgactt acccagccga
    33241 cctttaccta gaaggttctg accaataccg tggttggttt aactcatcac ttatcacatc
    33301 tgttgccaac catggcgtag caccttacaa acaaatcttg tcacaaggtt ttgcccttga
    33361 tggtaaaggt gagaagatgt ctaaatctct tggaaatacc attgctccaa gcgatgttga
    33421 aaaacaattc ggtgctgaaa tcttgcgtct ctgggtaaca agtgttgact caagcaatga
    33481 cgtgcgtatc tctatggata ttttgagcca agtttctgaa acttaccgta agattcgtaa
    33541 cactcttcgt ttcttgattg ccaatacatc tgactttaac ccagctcaag atacagtcgc
    33601 ttacgatgag cttcgttcag ttgataagta catgacgatt cgctttaacc agcttgtcaa
    33661 gaccattcgt gatgcctatg cagactttga attcttgacg atctacaagg ccttggtgaa
    33721 ctttatcaac gttgacttgt cagccttcta ccttgatttt gccaaagatg ttgtttacat
    33781 tgaaggtgcc aaatcactgg aacgccgtca aatgcagact gtcttctatg acattcttgt
    33841 caaaatcacc aaactcttga caccaatcct tcctcacact gcggaagaaa tttggtcata
    33901 tcttgagttt gaaacagaag acttcgtcca attgtcagaa ttaccagagg ctcaaacttt
    33961 tgctaaccaa gaagaaatct tggatacatg ggcagccttc atggacttcc gtggacaagc
    34021 acaaaaagcc ttggaagaag ctcgtaatgc aaaagttatc ggtaaatcac ttgaagcaca
    34081 cttgacagtt tatccaaatg aagtggtgaa aactctactc gaagcagtaa acagcaatgt
    34141 agctcaactt ttgatcgtgt cagacttgac catcgcagaa ggaccagctc cggaagctgc
    34201 ccttagcttc gaagatgtag ccttcacagt tgaacgtgct gctggtgaag tatgtgaccg
    34261 ttgccgtcgt atcgacccaa caacagcaga acgcagctac caggcagtca tctgtgatca
    34321 ttgtgcaagc atcgtagaag aaaactttgc ggacgctgtc gcagaaggat ttgaagagaa
    34381 ataagattga aaagtctagg caaaattcaa tttgagaaga aaagacaact aattttatag
    34441 tctattaaac gcattgtatc acgtttttga acacctgata tgatgcgttt tttatttatt
    34501 ttaaaaattt gcgaggtatg actttttata ctcaacaaga atcaaagaga aacttagcaa
    34561 gctaacagta gtaagataaa ataggaattt gatattaggg at
//
LOCUS       DBEJAU010000016        34107 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC323 isolate 683620
            SAMN38261939-rid24807223.denovo.016, whole genome shotgun sequence.
ACCESSION   DBEJAU010000016 DBEJAU010000000
VERSION     DBEJAU010000016.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261939
            Sequence Read Archive: SRR26833919
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 34107)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 34107)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576303.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576303.1
            Genome Coverage       :: 154x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/19/2025 01:05:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,121
            CDSs (total)                      :: 2,078
            Genes (coding)                    :: 1,943
            CDSs (with protein)               :: 1,943
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 36
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 72 of 135
            Pseudo Genes (incomplete)         :: 63 of 135
            Pseudo Genes (internal stop)      :: 51 of 135
            Pseudo Genes (multiple problems)  :: 46 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..34107
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261939-rid24807223.denovo.016"
                     /strain="GPSC323"
                     /isolate="683620"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            382..1545
                     /locus_tag="ACL29Z_000843"
     CDS             382..1545
                     /locus_tag="ACL29Z_000843"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001837533.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008168 - methyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0006364 - rRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent rRNA methyltransferase"
                     /protein_id="HGR0069177.1"
                     /translation="MNRIRVSKRVEKKLAKGLVLLEASDLENVNLKDQEVEVQGQEGN
                     FLGTAYLSQQNKGLGWFISKDKVAFNQAFFETLFRKAKEKRSAYYQDDLTTTYRLFNQ
                     EGDGFGGLTVDLYGDYAVFSWYNSYVYQIRQTISEAFRQVFPEVLGAYEKIRFKGLDY
                     ESAHVYGQEAPDFFTVLENGVLYQVFMNDGLMTGIFLDQHEVRGSLVDGLAMGKSLLN
                     MFSYTAAFSVAAAMGGASQTTSVDLAKRSRELSQAHFQANGLSTDEHRFIVMDVFEYF
                     KYAKRKNLTYDVIVLDPPSFARNKKQTFSVAKDYHKLISQSLEILNLGGIIIASTNAA
                     NVSRQKFTEQIDKGFAGRNYQILNKYGLPADFAYNKKDESSNYLKVISMKVSK"
     gene            1542..2219
                     /gene="aroD"
                     /locus_tag="ACL29Z_000844"
     CDS             1542..2219
                     /gene="aroD"
                     /locus_tag="ACL29Z_000844"
                     /EC_number="4.2.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000780376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003855 - 3-dehydroquinate dehydratase
                     activity [Evidence IEA];
                     GO_process: GO:0009423 - chorismate biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type I 3-dehydroquinate dehydratase"
                     /protein_id="HGR0069178.1"
                     /translation="MKLIVSVMPRSLEEAQALDTTRYLDADIIEWRADYLPKEAILQV
                     APAIFEKFAGRELVFTLRTRSEGGEIDLSPEEYIHLIKEVAQFYQPDYIDFEYYSYKD
                     VFEEMLDFPNLVLSYHNFQETPENMMEILSELTILNPKLVKVAVMAHTEQDVLDLMNY
                     TRGFKTLNPEQEYVTISMGKVGKVSRITADVTGSSWSFASLDEVSAPGQISLASMKKI
                     REILDEA"
     gene            2209..3063
                     /locus_tag="ACL29Z_000845"
     CDS             2209..3063
                     /locus_tag="ACL29Z_000845"
                     /EC_number="1.1.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004258171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="shikimate dehydrogenase"
                     /protein_id="HGR0069179.1"
                     /translation="MKLDGYTRLAAVVANPIKHSISPFIHNRAFEATATNGAYVAWEI
                     EASDLAETVANIRRYQMFGINLSMPYKEQVIPYLDKLSDEARLIGAVNTVVNENGNLI
                     GYNTDGKGFFKCLPSFTISGKKMTLLGAGGAAKSILAQAILDGVSQISVFVRSVSMEK
                     TRPYLDKLQEQTGFKVDLCALEYVSELQARIAESDLLVNATSVGMDGQSSPVPENIVL
                     PETLLVADIIYQPFETPFLKWARSQGNPAVNGLGMLLYQAAEAFQLWTGKEMPTEEIW
                     QSLTEKYQ"
     gene            3082..4149
                     /gene="aroB"
                     /locus_tag="ACL29Z_000846"
     CDS             3082..4149
                     /gene="aroB"
                     /locus_tag="ACL29Z_000846"
                     /EC_number="4.2.3.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0003856 - 3-dehydroquinate synthase
                     activity [Evidence IEA];
                     GO_process: GO:0009073 - aromatic amino acid family
                     biosynthetic process [Evidence IEA];
                     GO_process: GO:0009423 - chorismate biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="3-dehydroquinate synthase"
                     /protein_id="HGR0069180.1"
                     /translation="MKIRIDIPHHPYDIQIEKGCMAQAGQWLRELWQPQKVVIVTDNH
                     VASLYAEKVKLSLEDAGFQVAVFDFLEGEERKNLTTVQKVYEFLVKQGLTRSDGIVAL
                     GGGVVGDLAGFVASTYMRGIHFVQIPTSLTAQVDSSIGGKTGVNTPFAKNMVGTFAQP
                     DGVLIDPLVLETLGKRELIEGMGEVIKYGLIEDPELWTLLTGLNGSVESILEHAETLI
                     EHSCQVKRKMVVEDELDNGIRLYLNFGHTIGHAIEATAGYGKVMHGEAVAMGMVQISK
                     IAEEKGLMPAGITQSITEMCQKFGLPVDYENWEVDKLYQALTHDKKARGNTLKLVLVP
                     ELGSATIHPVSLEEMKDYLVK"
     gene            4159..5325
                     /gene="aroC"
                     /locus_tag="ACL29Z_000847"
     CDS             4159..5325
                     /gene="aroC"
                     /locus_tag="ACL29Z_000847"
                     /EC_number="4.2.3.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004259785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004107 - chorismate synthase activity
                     [Evidence IEA];
                     GO_process: GO:0009073 - aromatic amino acid family
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="chorismate synthase"
                     /protein_id="HGR0069181.1"
                     /translation="MRYLTAGESHGPRLTAIIEGIPAGLPLTAEDINEDLRRRQGGYG
                     RGGRMKIESDQVVFTSGVRHGKTTGAPITMDVINKDHQKWLDIMSAEDIEDRLKSKRK
                     ITHPRPGHADLVGGIKYRFDDLRNSLERSSARETTMRVAVGAVAKRLLAELDMEIANH
                     VVVFGGKEIDVPENLTVAEIKQRAAQSEVSIVNQEREQEIKDYIDQIKRDGDTIGGVV
                     ETVVGGVPVGLGSYVQWDRKLDARLAQAVVSINAFKGVEFGLGFEAGYRKGSQVMDEI
                     LWSKEDGYTRRTNNLGGFEGGMTNGQPIVVRGVMKPIPTLYKPLMSVDIETHEPYKAT
                     VERSDPTALPAAGMVMEAVVATVLAQEILEKFSSDNLEELKEAVAKHRDYTKNY"
     gene            5335..6438
                     /locus_tag="ACL29Z_000848"
     CDS             5335..6438
                     /locus_tag="ACL29Z_000848"
                     /EC_number="1.3.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001140485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prephenate dehydrogenase"
                     /protein_id="HGR0069182.1"
                     /translation="MAKTIYIAGLGLIGASMALGIKRDHPDYEILGYNRSQASRDIAL
                     KEGMIDRATDDFASFAPLADVIILSLPIKQTIAFIKELANLDLREGVIISDAGSTKST
                     IVDAAEQYLAGKSVRFVGAHPMAGSHKTGAASADVNLFENAYYIFTPSSLTSQDTLKE
                     MKDLLSGLHARFIEIDAKEHDRVTSQISHFPHILASSLMEQTAVYAQEHEMARRFAAG
                     GFRDMTRIAESEPGMWTSILLSNSETILDRIEDFKERLEAIGQAISKGDEEQIWNFFN
                     QAREQRQTMEIHKRGGVDSSYDLYVDVPDEEDVILRILELLRGTSLVNIHINEENRED
                     IHGILQISFKNAQDLERAEHLITKNTDYTVVIK"
     gene            6449..6787
                     /locus_tag="ACL29Z_000849"
     CDS             6449..6787
                     /locus_tag="ACL29Z_000849"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000065990.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlbF/YmcA family competence regulator"
                     /protein_id="HGR0069183.1"
                     /translation="MSNIYDSANELSRGLRGLPEYKAVKAAKDAIAADAEASKIFTEY
                     LAFQEEIQKLAQTGQMPDASFQAKMEGFGKQIQGNSLLSEFFTKQQQLAIYLSDIEKI
                     VFEPVSELLK"
     gene            6879..8162
                     /gene="aroA"
                     /locus_tag="ACL29Z_000850"
     CDS             6879..8162
                     /gene="aroA"
                     /locus_tag="ACL29Z_000850"
                     /EC_number="2.5.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004236106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003866 - 3-phosphoshikimate
                     1-carboxyvinyltransferase activity [Evidence IEA];
                     GO_process: GO:0009073 - aromatic amino acid family
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="3-phosphoshikimate 1-carboxyvinyltransferase"
                     /protein_id="HGR0069184.1"
                     /translation="MKLKTNIRHLHGSIRVPGDKSISHRSIIFGSLAEGETKVYDILR
                     GEDVLSTMQVFRDLGVEIEDKDGVITVQGVGMAGLKAPQNALNMGNSGTSIRLISGVL
                     AGADFEVEMFGDDSLSKRPMDRVTLPLKKMGVSISGQTERDLPPLRLKGTKNLRPIHY
                     ELPIASAQVKSALMFAALQAKGESVIIEKEYTRNHTEDMLQQFGGHLSVDGKKITVQG
                     PQKLTGQKVVVPGDISSAAFWLVAGLIAPNSRLVLQNVGINETRTGIIDVIRAMGGKL
                     EITEIDPVAKSATLIVESSDLKGTEICGALIPRLIDELPIIALLATQAQGVTVIKDAE
                     ELKVKETDRIQVVADALNSMGADITPTADGMIIKGKSALHGARVNTFGDHRIGMMTAI
                     AALLVADGEVELDRAEAINTSYPSFFDDLESLIHG"
     gene            8155..8631
                     /locus_tag="ACL29Z_000851"
     CDS             8155..8631
                     /locus_tag="ACL29Z_000851"
                     /EC_number="2.7.1.71"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000287 - magnesium ion binding [Evidence
                     IEA];
                     GO_function: GO:0004765 - shikimate kinase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0008652 - amino acid biosynthetic process
                     [Evidence IEA];
                     GO_process: GO:0009073 - aromatic amino acid family
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="shikimate kinase"
                     /protein_id="HGR0069185.1"
                     /translation="MAKVLLGFMGAGKSSIARGLDPNYLDMDALIEKRLGMSIANFFA
                     EKGEAAFRQVESEVLADLLQRDQVVSTGGGVVISQRNRDLLKTNTDNIYLKADFETLY
                     LRIAADKDNQRPLFLNNSKEELVAIFQERQAWYEEVASRVLDVTKLSPEEIIEELR"
     gene            8628..9476
                     /gene="pheA"
                     /locus_tag="ACL29Z_000852"
     CDS             8628..9476
                     /gene="pheA"
                     /locus_tag="ACL29Z_000852"
                     /EC_number="4.2.1.51"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001865057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004664 - prephenate dehydratase activity
                     [Evidence IEA];
                     GO_process: GO:0009094 - L-phenylalanine biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="prephenate dehydratase"
                     /protein_id="HGR0069186.1"
                     /translation="MKIAYLGPKGSFSHHVVQTAFPHEELQAFANITDVIKAYEQGLV
                     DYSVVPVENSIEGSVHETLDYLFHQAHIQAVAEIVQPIHQQLMVVPGHTKIEKIFSHP
                     QALAQGKKFIDEQYPEAQIEVTASTAYAARFISEHPDQPFAAIAPRSSAEEYGLELIA
                     EDIQEMEANFTRFWLLGAEKPSIPLQAQTEKMSLALTLPDNLPGALYKALSTFAWRGI
                     DLTKIESRPLKTALGEYFFIIDVDYTDKDLVHFAQKELEAIGIQYKILGAYPIYPISD
                     HGKERR"
     gene            9473..10747
                     /gene="psr"
                     /locus_tag="ACL29Z_000853"
     CDS             9473..10747
                     /gene="psr"
                     /locus_tag="ACL29Z_000853"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000032347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyisoprenyl-teichoic acid--peptidoglycan
                     teichoic acid transferase Psr"
                     /protein_id="HGR0069187.1"
                     /translation="MSKENPLSHHEQLRYDYLLKNIHYLNEREKNEFVYLQEKLTLAR
                     GNSSSSLEQEREEQVDLPSYANRSRSQSKSQALSFPPKKKRRKLRLKRIFMVIFSLLV
                     CVALAMVFMFLRGYQDASAKKTADARAAQVEVFNGQDTRDGVNILIMGTDGRIGQNSV
                     ETRTDSIMVLNVGGSDKKMKLVSFMRDNLVYIDGYSQVINGRKQTDNKLNVAYELGEQ
                     EGQKGAEMVRQVLKDNFDLDIKYYALVDFQAFATAIDTLFPDGVTIDAQFSTLNGRPL
                     TEATVGDDLYATETESPTQTIKVGKQQMNGSTLLNYARFRDDDEADYGRTKRQQQVLT
                     AILEQIKDPTKLFTGSEALGKVFAMTSTNVPYTFLLTNGLSVLDGAKNGIEKLTIPEL
                     GDWVDAYDVYGGLGLLVDQNKYQTKLAQMGLR"
     gene            11026..11871
                     /locus_tag="ACL29Z_000854"
     CDS             11026..11871
                     /locus_tag="ACL29Z_000854"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001061982.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphorylcholine transferase LicD"
                     /protein_id="HGR0069188.1"
                     /translation="MNNMTDLKAIQARSLEMAEYFVAFCKEHDLLCYLCGGGAIGALR
                     NKGFIPWDDDLDFFMPRKDYEKLAELWPRYADERYFLSKSHKNFVDRNLFITIRDKET
                     TCIKPYQQDLDLPHGLALDVLPLDYYPKNPAERKKQVRWALIYSLFCAQTIPEKHGAL
                     MKWGSRILLGLTPKSLRYRIWKKAEKEMTKYDLADCDGITELCSGPGYMRNKYPITSF
                     EDNLFLPFEGTEMPIPIGYDVYLRTAFGDYMTPPPADKQVPHHDAVIADMDKSYTEYK
                     GEYGG"
     gene            11861..12964
                     /locus_tag="ACL29Z_000855"
     CDS             11861..12964
                     /locus_tag="ACL29Z_000855"
                     /EC_number="2.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000225894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016757 - glycosyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HGR0069189.1"
                     /translation="MVAKKKILFFMWSFSLGGGAEKILSTIVSNLDPEKYDIDILEME
                     HFDKGYESVPKHVRILKSLQDYRQTRWLRAFLWRMRIYFPRLTRRLLVKDDYDVEVSF
                     TIMNPPLLFSKRREVKKISWIHGSIEELLKDSSKRESHRSQLDAANTIVGISKKTSNS
                     IKEVYPDYASKLQTIYNGYDFQTILEKSQEKIDIEIAPQSICTIGRIEENKGSDRVVE
                     VIRLLHQEGKNYHLYFIGAGDMEEELKKRVKEYGIEDYVHFLGYQKNPYQYLSQTKVL
                     LSMSKQEGFPGVYVEALSLGLPFISTDVGGAEELSQEGRFGQIIESNQEAAQAIINYM
                     TSASNFDVDEASQFIQQFTITKQIEQVEKLLEE"
     gene            12966..13952
                     /locus_tag="ACL29Z_000856"
     CDS             12966..13952
                     /locus_tag="ACL29Z_000856"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000446977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HGR0069190.1"
                     /translation="METALISVIVPVYNVAQYLEKSIASIQKQTYQNLEIILVDDGAT
                     DESGRLCDSIAEQDDRVSVLHKKNEGLSQARNDGMKQAHGDYLIFIDSDDYIHPEMIQ
                     SLYEQLVQEDADVSSCGVMNVYANDESPQSANQDDYFVCDSQTFLKEYLIGEKIPGTI
                     CNKLIKRQIATDLSFPKGLIYEDAYYHFDLIKLAKKYVVNTKPYYYYFHRGDSITTKP
                     YAEKDLAYIDIYQKFYNEVVKNYPDLKEVAFFRLAYAHFFILDKMLLDDQYKQFEAYS
                     QIHRFLKGHAFAISRNPIFRKGRRISALALFINISLYRFLLLKNIEKSKKLH"
     gene            13968..15401
                     /locus_tag="ACL29Z_000857"
     CDS             13968..15401
                     /locus_tag="ACL29Z_000857"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000565082.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="O-antigen polysaccharide polymerase Wzy family
                     protein"
                     /protein_id="HGR0069191.1"
                     /translation="MIDGKRLLFSLTIVSYTLTIVSGIVYLFNNNNVSLLSTLLFLLV
                     SSLIACWNDIKYYLIHFIFYLTIFVFLVSRPTIDYFRDGALDTYHPIAYRFAFIVVMV
                     SILGLTTGGVLARYFIARKKIKVANIGNSLKEVYIKRLRFVSLGVFLLTYPFYFIRLF
                     ERLLYRLQTSYYAYYANFESKLPYFTYILSTFTVYAMCMYLATKPKKLQATAVLVSFI
                     AANTIHLAIGTRNPFILSILFAFVYYFMREQTEKGKWIGFKEKLAIFVGSPILMLAMG
                     VLNYVRDNVQVSHTGFWDILLDFIYKQGTSFGVLARGFLFNSSLPYRDFRNFTFGPVL
                     DYFARGSLGAIFGGKAFEHTTNSVELAIDSNSYAHNLSYLVLNKEYLKGHGIGSSYIM
                     ELYTDYGMIGVFLLSFLLGVLFIAMLQVAYRSRTILFALSLLILNNLFFMPRSSFSES
                     FFNLFTMQFWGIVLVIIFVAKMLTKEN"
     gene            15430..16464
                     /locus_tag="ACL29Z_000858"
     CDS             15430..16464
                     /locus_tag="ACL29Z_000858"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000461501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prephenate dehydratase"
                     /protein_id="HGR0069192.1"
                     /translation="MFEHYSVADLFANLYKKRKANILALIALFALIAVPFTIKAVRNK
                     NTVKDTTSYSTYLIYKITPPEDSAKTILNHQIGGYSDFYGKLIDGNLNGAYLFNDVEP
                     SELKKIASELDTTETTLKNSTNDYWWKKLTVYYMIDDAGVGVKILTSSKDANDLLEKK
                     IDGLIEKFKHAYANVKIEKLETINSKELNANGETALGLNVKNLILRLVVIGVVCVILV
                     VMGNVLVYLFNPTINRVGDFSQYQIDFVTEITTIANLADVLSYKNTGQELTIVSSNKA
                     ILDKLKQSQEALKGMHFVDLQDVSSLLERDTVLLVEEYGVTRYKKFEQSLQILRNLNR
                     SILGVATFKL"
     gene            16664..17401
                     /gene="mecA"
                     /locus_tag="ACL29Z_000859"
     CDS             16664..17401
                     /gene="mecA"
                     /locus_tag="ACL29Z_000859"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000782680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adaptor protein MecA"
                     /protein_id="HGR0069193.1"
                     /translation="MKMKQISDTTLKITMSLEDLMDRGMEIADFLVPQEKTEEFFYAI
                     LDELEMPDSFLDTGMLSFRVTPKPDKVDVFVTKSKIDQNLDFEDLSDLPDMEELAQMS
                     PDEFIKTLEKSIADKTKDDIEAIQSLEQVEAKEEEQEQAEQEAESKKEPYIYYILSFA
                     KLADLVAFAKTVTFEMETSELYKMNERYYLTILVDIENHPSPYPAWLLARMREFADDS
                     DISRSVLQEYGQVLMSHDAVLNLQKIG"
     gene            17552..18838
                     /locus_tag="ACL29Z_000860"
     CDS             17552..18838
                     /locus_tag="ACL29Z_000860"
                     /EC_number="1.1.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004412 - homoserine dehydrogenase
                     activity [Evidence IEA];
                     GO_process: GO:0006520 - amino acid metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="homoserine dehydrogenase"
                     /protein_id="HGR0069194.1"
                     /translation="MTVKIALLGFGTVASGVPFLLKENGGKINQSAHSDIKVAKVLVK
                     DEDEKNRLLAAGNDFNFVTNVDDILSDQDITIVVELMGRIEPAKTFITRALEAGKHVV
                     TANKDLLAVHGAELLEIAQANKVALYYEAAVAGGIPILRTLANSLASDKITRVLGVVN
                     GTSNFMVTKMVEEGWSYDDALAEAQRLGFAESDPTNDVDGIDAAYKMVILSQFAFGMK
                     IAFDDVAHKGIRNITPEDVAVAQELGYVVKLVGSIEETSSGIAAEVTPTFLPKAHPLA
                     SVNGVMNAVFVESIGIGESMYYGPGAGQKPTATSVVADIVRIVRRLNDGTIGKDFNEY
                     SRDLVLANPEDVKANYYFSILALDSKGQVLKLAEIFNAQDISFKQILQDGKEGDKARV
                     VIITHKINKAQLENVSAELKKVSEFDLLNTFKVLGE"
     gene            18840..19709
                     /gene="thrB"
                     /locus_tag="ACL29Z_000861"
     CDS             18840..19709
                     /gene="thrB"
                     /locus_tag="ACL29Z_000861"
                     /EC_number="2.7.1.39"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000692406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004413 - homoserine kinase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0009088 - threonine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="homoserine kinase"
                     /protein_id="HGR0069195.1"
                     /translation="MKIIVPATSANIGPGFDSVGVAVTKYLQIEVCEERDEWLIEHQI
                     GKWIPHDERNLLLKIALQIVPDLQPRRLKMTSDVPLARGLGSSSSVIVAGIELANQLG
                     QLNLSDHEKLQLATKIEGHPDNVAPAIYGNLVIASSVEGQVSAIVADFPECDFLAYIP
                     NYELRTRDSRSVLPKKLSYKEAVAASSIANVAVAALLAGDMVTAGQAIEGDLFHERYR
                     QDLVREFAMIKQVTKENGAYATYLSGAGPTVMVLASHDKMPTIKAELEKQPFKGKLHD
                     LRVDTQGVRVEAK"
     gene            19959..20897
                     /gene="msrB"
                     /locus_tag="ACL29Z_000862"
     CDS             19959..20897
                     /gene="msrB"
                     /locus_tag="ACL29Z_000862"
                     /EC_number="1.8.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001865281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0033743 - peptide-methionine (R)-S-oxide
                     reductase activity [Evidence IEA];
                     GO_process: GO:0006979 - response to oxidative stress
                     [Evidence IEA];
                     GO_process: GO:0030091 - protein repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (R)-S-oxide reductase MsrB"
                     /protein_id="HGR0069196.1"
                     /translation="MAEIYLAGGCFWGLEEYFSRISGVLETSVGYANGQVETTNYQLI
                     KETDHAETVQVIYDEKEVSLREILLYYFRVIDPLSINQQGNDRGRQYRTGIYYQDEAD
                     LPAIYTVVQEQERMLGRKIAVEVEQLRHYILAEDYHQDYLRKNPSGYCHIDVTDADKP
                     LIDAANYEKPSQEVLKTSLSEESYRVTQEAATEAPFTNAYDQTFEEGIYVDITTGEPL
                     FFAKDKFASGCGWPSFSRPISKELIHYYKDLSHGMERIEVRSRSGSAHLGHVFTDGPR
                     ELGGLRYCINSASLRFVAKDEMEKAGYGYLLPYLNK"
     gene            20955..22679
                     /locus_tag="ACL29Z_000863"
     CDS             20955..22679
                     /locus_tag="ACL29Z_000863"
                     /EC_number="7.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGR0069197.1"
                     /translation="MKHLLSYFKPYIKESILAPLFKLLEAVFELLVPMVIAGIVDQSL
                     PQGDQGHLWMQIGLLLIFAVIGVLVALIAQFYSAKAAVGFAKELTNDLYRHILSLPKD
                     SRDRLTTSSLVTRLTSDTYQIQTGINQFLRLFLRAPIIVFGAIFMAYRISTELTFWFL
                     VMVAILTIVIVGLSRLVNPLYSSLRKKTDQLVQETRQQLQGMRVIRAFGQEKRELQIF
                     QTLNQVYARLQEKTGFWSSLLTPLTYLIVNGTLLVIIWQGYISIQGGVLSQGALIALI
                     NYLLQILVELVKLAMLINSLNQSYISAKRIEEVFAESPENIHSELEQKQVTSGRVLQV
                     QELTFTYPDAAQPSLRDISFDMTQGQILGIIGGTGSGKSSLVQLLLGLYPVDKGNIDL
                     YQNGRSPLNLEQWRSWIAYVPQKVKLFKGTIRSNLTLGLNQEVSDQKLWQALEIAQAK
                     DFVSEKEGLLDALVEAGGRNFSGGQKQRLSIARAVLRQAPFIILDDATSALDTITESK
                     LLKAIRENFPNTSLILISQRTSTLQMADQILLLEKGELLAVGKHDDLMKSSQVYREIN
                     ASQHGKED"
     gene            22681..24429
                     /locus_tag="ACL29Z_000864"
     CDS             22681..24429
                     /locus_tag="ACL29Z_000864"
                     /EC_number="7.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000828810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGR0069198.1"
                     /translation="MKRQTVNQTLKRLAVDLANHPFLLFLAFLGTIAQVGLSIYLPIL
                     IGQVIDQVLVAGSSPVFWQIFLQMLLVVIGNTLVQWANPLLYNRLIFSYTRDLRERII
                     HKLHRLPIAFVDRQGSGEMVSRVTTDIEQLAAGLTMIFNQFFIGVLMILVSILAMLQI
                     HLLMTLLVLLLTPLSMVISRFIAKRSYHLFQKQTETRGIQTQLIEESLSQQTIIQSFN
                     AQTEFIQRLREAHDNYSGYSQSAIFYSSTVNPSTRFVNALIYALLAGVGAYRIMMGST
                     LTVGRLVTFLNYVQQYTKPFNDISSVLAELQSALACVERIYGVLDSPEVAETGKEVLT
                     SDQVKGAISFKHVSFGYHPEKILIKDLSIDIPAGSKIAIVGPTGAGKSTLINLLMRFY
                     PISSGDILLDGQSIYDYTRASLRQQFGMVLQETWLTQGTIHDNIAFGNPEASREQVIA
                     AAKAANADFFIQQFPQGYDTKLENAGESLSVGQAQLLTIARVFLAIPKILILDEATSS
                     IDTRTEVLVQDAFAKLMKGRTSFIIAHRLSTIQDADLILVLVDGDIVEYGNHQELMDR
                     KGKYYQMQKAAAFSSE"
     gene            24686..25945
                     /locus_tag="ACL29Z_000865"
     CDS             24686..25945
                     /locus_tag="ACL29Z_000865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TRZ/ATZ family protein"
                     /protein_id="HGR0069199.1"
                     /translation="MKVFQHVNIVTCDQDFHVYLDGILAVKDSQIVYVGQDKPAFLEQ
                     AEQIIDYQGAWIMPGLVNCHTHSAMTGLRGIRDDSNLHEWLNDYIWPAESEFTPDMTT
                     NAVKEALTEMLQSGTTTFNDMYNPNGVDIQQIYQVVKTSKMRCYFSPTLFSSETETTA
                     ETISRTRSIIDEILKYKNPNFKVMVAPHSPYSCSRDLLEASLEMAKELNIPLHVHVAE
                     TKEESGIILKRYGKRPLAFLEELGYLDHPSVFAHGVELNEREIELLASSQVAIAHNPI
                     SNLKLASGIAPIIQLQKAGVVVGIATDSVASNNNLDMFEEGRTAALLQKMKSGDASQF
                     PIETALKVLTIEGAKVLGMENQIGSLEVGKQADFLVIQPQGKIHLQPQENMLSHLVYA
                     VKSSDVDDVYIAGEQVVKQGQVLTVEL"
     misc_feature    26021..26156
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00557"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="ribosomal protein L10 leader region; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF00557"
     gene            26195..26695
                     /gene="rplJ"
                     /locus_tag="ACL29Z_000866"
     CDS             26195..26695
                     /gene="rplJ"
                     /locus_tag="ACL29Z_000866"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001287276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015934 - large ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L10"
                     /protein_id="HGR0069200.1"
                     /translation="MSEAIIAKKAELVDVVAEKMKAAASIVVVDARGLTVEQDTVLRR
                     ELRGSEVEYKVIKNSILRRAAEKAGLEDLASVFVGPSAVAFSNEDVIAPAKILNDFSK
                     NAEALEIKGGAIEGAVASKEEILALATLPNREGLLSMLLSVLQAPVRNVALAVKAVAE
                     SKEDAA"
     gene            26771..27139
                     /gene="rplL"
                     /locus_tag="ACL29Z_000867"
     CDS             26771..27139
                     /gene="rplL"
                     /locus_tag="ACL29Z_000867"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018371186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L7/L12"
                     /protein_id="HGR0069201.1"
                     /translation="MALNIENIIAEIKEASILELNDLVKAIEEEFGVTAAAPVAVAAA
                     DAADAGAAKDSFDVELTSAGDKKVGVIKVVREITGLGLKEAKELVDGAPALVKEGVAT
                     AEAEEIKAKLEEAGASVTLK"
     gene            27326..27496
                     /locus_tag="ACL29Z_000868"
     CDS             27326..27496
                     /locus_tag="ACL29Z_000868"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001168347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0069202.1"
                     /translation="MQKEGQSSRQFMKSHLMTIMGVDIVKATQLVDEMEQVGLIRFDE
                     FGNVGILVLEGQ"
     gene            27496..27744
                     /locus_tag="ACL29Z_000869"
                     /pseudo
     CDS             27496..27744
                     /locus_tag="ACL29Z_000869"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017648301.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiator protein A"
     gene            27758..28081
                     /locus_tag="ACL29Z_000870"
     CDS             27758..28081
                     /locus_tag="ACL29Z_000870"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001134542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0069203.1"
                     /translation="MTFLDDYHKKHNYPLFYESYLQNVMEFLESQDIKNGVDAFVDDH
                     QNLVFVLYGQGYRAEGKEGILTTQVTVKAYDEDKKPINFANLLDSLIVSEYQMEPNLW
                     EVSYD"
     gene            28074..28454
                     /locus_tag="ACL29Z_000871"
     CDS             28074..28454
                     /locus_tag="ACL29Z_000871"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000565031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0069204.1"
                     /translation="MIDLYLSKNSRRNQLLLDFFQNYGIEVSCHSVSEMTKDKLIEMM
                     SYSSDCFEFLSPNLLRFKNRDNLKLTDFIEMILKNPELTIRLPLAVSNKRVYPSLNLE
                     EARALLPRDTKQLIYMAQTHYLSN"
     gene            28467..28700
                     /locus_tag="ACL29Z_000872"
     CDS             28467..28700
                     /locus_tag="ACL29Z_000872"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000840775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HGR0069205.1"
                     /translation="MAERFWENLSIILAERNISWIELTRKMFAGEFHYPSELNRLYQK
                     IRHYKMEQRMPQSPWVERIVQVLDLDYEDLFRR"
     gene            28703..29290
                     /locus_tag="ACL29Z_000873"
     CDS             28703..29290
                     /locus_tag="ACL29Z_000873"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000821297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II CAAX endopeptidase family protein"
                     /protein_id="HGR0069206.1"
                     /translation="MKRIIPVYIFQQVNVLLVSLYLLKFLCIGELTILQILYCASLIS
                     FLWMYAQRKQAHKVNMKLRIKWIGIGLASLLIISLCFSLIHAQESTNQANLIGLQYQV
                     PWFSFLLFLINASMVEEFLYREILWNLVRKLDIRVALTSVLFALAHHPGTIIAWCLYV
                     SLGMFLGLVRYKLDLWGSMGLHLVWNLLVYSLLLF"
     gene            29492..29629
                     /locus_tag="ACL29Z_000874"
                     /pseudo
     CDS             29492..29629
                     /locus_tag="ACL29Z_000874"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004264816.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="SapB/AmfS family lantipeptide"
     gene            29919..31322
                     /locus_tag="ACL29Z_000875"
     CDS             29919..31322
                     /locus_tag="ACL29Z_000875"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0069207.1"
                     /translation="MNNDEWVYQYPIGKFVERQGWKIHISSEYNSSHELLQDVAKICH
                     EMRIPFKHLSTEDKFIMRNGKLVSRGFSGKFITCYPNQNELESVLQKLESALKQYNGP
                     YILSDKRWDEVPIYLRYGVFRPSRDDEKKVAIDELIVGDEVVKDERLPVFKIPKGIVP
                     PDFLNKWLDKKDKKQGDFPFIIDNAIRFSNSGGIYNARLKEDGKKIILKEARPYTGLG
                     FDGTYSSERLASECKALKILNEWSETPKIYWCGKIWEHTFLGIEHMKGVPLNRWVTNN
                     FPLYEVVDKTKDYLLRVSKIVEKLIDLTNKFHSENVYHQNLHLGNILVKDEDEISIID
                     WEQAVFSNDEKVVHKVAAPGFRAWRETLPSEIDWYGIRQIAHYLYMPLVTTSDLTYNY
                     VSQTRIEGKKLFESLGYTREHIDYVESLLSYLDSKCPQIENISRKKVLKPMHEIRTIE
                     SEQDIQDFIIKAFLLVN"
     gene            31511..32131
                     /locus_tag="ACL29Z_000876"
     CDS             31511..32131
                     /locus_tag="ACL29Z_000876"
                     /inference="COORDINATES: protein motif:HMM:NF012235.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HGR0069208.1"
                     /translation="MKDVVYSITPENKLSIDFSFKSPFRVLLTGTSGSGKTTILNLIN
                     GSLKPQKGYVNLLSHGKKSSDSIPTVDQTPYIFDTTIRENVTLFQNEYFSDDQIIEVL
                     KKVNLYEELEKIDILNYQCGENGSNLSGGQKQKIALARALIRNNKVYLFDEISANLDN
                     DNSNSIHDILFNLGISFIEVSHHYDLNDKRYTDIYKLENGTLFKIK"
     gene            32146..32886
                     /locus_tag="ACL29Z_000877"
     CDS             32146..32886
                     /locus_tag="ACL29Z_000877"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000356590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGR0069209.1"
                     /translation="MDKDYILKVKGLYHQFLLGNNKTLQVLKNVSLSASRGEFISILG
                     ISGSGKSTLLKCISSLLEPTSGEVILNGINPYKIRNAKLSSIRRNEVSFIFQAYNLIP
                     SLPVIENIALPLRLSQKKLTIKNVENLLKRMKFNAGLNDFVGTLSGGEQQKVAIARAV
                     IADSDIIFADEPTGALDSVSREVIFELLRELVGAGKCVIMVTHDIELASKTDRALILK
                     DGKIFKELHRPSGEELYKILEVQSTTEE"
     gene            32889..>34107
                     /locus_tag="ACL29Z_000878"
     CDS             32889..>34107
                     /locus_tag="ACL29Z_000878"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000945307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0069210.1"
                     /translation="MLRLVYYQFLHNKKQWLGVSPVIFVSSLVMGLAVNGVINVENNS
                     QVFVGLPDPKPIFMFPIVFGGVTLFFVLSNIINMLVEIFRDDYELLEVLGASLLQLSF
                     LVGGQIFIISSIISFIAYLCSIFVTSNYYYFLQYFFGENILPDIQFQTSAVGCIITVV
                     LISFLAFLSGCFYTFKKIRNRKSSKIRHVLSIVKRILLLAGFSVIWLLSLQQIFQDST
                     ILAKAQIIFNIVILDIVIIYQLSPFIQSCFIKLLSIIIFRNNFMFIVSKWNLLYRKPY
                     IKSISAAITGAILLISSFQMISQNILSQFQDDSDLELKVAFIVYVGAPILIVLANIIS
                     IAFLSSHQERIEIQQFEILGTSNYQMVKIKVGEAIFLTFVTSLIAFLLNIKIMALIYY
                     SLEDILIDDMNLLG"
BASE COUNT        10383 a         6008 c         7468 g        10248 t
ORIGIN      
        1 tagtatattg agtttgtaac aaaaggcttc tctaaaaatc aaattttcca gatacctact
       61 gaagctgatt tatttcttca tctttcttct actaccttta ctacctttgt cactaaattt
      121 gacagacaca tattgctgat acaacctctc tacctataat ctcacagtta acctgaggct
      181 agtttcatag tttgctattt gattttcgtt gataataaaa aatgctcctc caagacggaa
      241 gagcattttt tattgtgatt cttacacatt tacttcctag ttttgcagga agtctagtat
      301 accatttttt aaaagaagag taaaaaagca agggtagttt cttttttgag aattgtctaa
      361 aagtttgata taatggtagt tatgaataga ataagagtca gcaaaagggt tgaaaagaag
      421 cttgctaagg ggctagtttt actagaagcc agtgatcttg agaatgtcaa tcttaaggat
      481 caggaagtag aggtgcaggg tcaggaagga aactttcttg ggactgccta cctttctcag
      541 caaaacaagg gcttgggctg gtttatcagc aaagacaagg tggccttcaa tcaagctttc
      601 tttgaaacgt tgtttagaaa agccaaagaa aagagaagcg cctactatca agatgattta
      661 acaactacct atcgtctctt taatcaagag ggagatggct ttgggggtct gacagtggac
      721 ctttatggcg actacgccgt cttttcttgg tataactctt atgtttatca gattcgtcag
      781 actatatcag aagcctttag acaggttttc cctgaggttt taggggctta tgagaaaatc
      841 cgctttaagg gtttggacta tgaatctgcc catgtttatg gtcaagaagc acctgacttt
      901 ttcactgttt tagaaaatgg tgtcctgtat caagtcttta tgaatgatgg cttgatgaca
      961 ggaattttcc tagaccagca tgaggttcgc ggtagtttag ttgacggctt ggctatgggt
     1021 aaatccttgc tcaatatgtt ttcctacaca gcggcttttt cagtagctgc ggccatggga
     1081 ggagctagcc agacaacttc tgttgatcta gccaaacgtt cacgagaatt gtctcaagcg
     1141 cattttcagg caaatgggct cagcacagac gagcatcgtt ttatagtcat ggatgtcttt
     1201 gagtatttca aatatgccaa acgcaaaaac ttgacctacg atgtgattgt cctagatccg
     1261 cctagctttg ctcggaataa aaaacaaact ttctctgtgg ccaaggatta tcacaagttg
     1321 atttcccaga gtcttgagat tttaaatctg ggagggatta tcattgccag taccaatgct
     1381 gccaatgttt cccgtcagaa atttacagaa caaattgata aaggctttgc aggaagaaat
     1441 taccagattt taaacaaata tggtcttcca gcagattttg cctataataa aaaagatgaa
     1501 agtagtaatt acctcaaggt gattagtatg aaggttagta aatgaaatta atcgtttcag
     1561 taatgccaag aagtttagag gaggctcagg ctctggatac cacgaggtac ctggatgccg
     1621 acatcattga atggcgtgcc gactatctgc ctaaagaagc gattttgcag gtagctccag
     1681 ccatttttga aaaattcgca ggccgtgagt tggttttcac gctacgaact cgctccgaag
     1741 gtggagaaat cgacctttct ccagaagagt atatccatct aatcaaggaa gttgcgcaat
     1801 tctatcaacc agactatatt gattttgagt actatagcta caaggatgtt tttgaggaaa
     1861 tgctggactt cccaaatctt gttttgagtt accataattt ccaagaaaca cctgagaaca
     1921 tgatggaaat cttgtcagag ttgacgatcc taaatccaaa acttgttaag gttgcggtga
     1981 tggctcacac ggagcaggat gtcttagact tgatgaacta tacacgaggc tttaaaaccc
     2041 tcaatcctga acaggaatat gtgaccattt ctatgggtaa ggtgggcaag gtctctcgta
     2101 tcactgcgga tgtgactggt tcgagttggt cttttgccag tctggatgag gttagtgccc
     2161 ctgggcagat ttctctagct agcatgaaaa aaatcaggga gattttggat gaagcttgat
     2221 ggctatacac gtttagctgc agttgttgcc aatcctatta agcattctat ttctcccttc
     2281 atccacaata gagcctttga ggcgacagct accaacggtg cttatgtggc ttgggagatt
     2341 gaagcgagtg acttggcaga aacagtggcc aatattcgtc gctaccagat gtttggcatc
     2401 aatctgtcca tgccctataa ggagcaggtg attccttatt tggataagct gagcgatgaa
     2461 gcgcgcttga ttggtgcggt taatacggtt gtcaatgaga atggcaattt aattggatat
     2521 aatacagatg gcaagggatt ttttaagtgc ttgccttctt ttacaatttc aggtaaaaag
     2581 atgaccctgc tgggtgcagg tggtgcggct aaatcaatct tggcacaggc tattttggat
     2641 ggcgtcagtc agatttcggt ctttgttcgt tccgtttcta tggaaaaaac aagaccttac
     2701 ctagacaagt tacaggagca gacaggtttt aaagtggatt tgtgtgcttt agagtatgtt
     2761 tctgaactgc aagcaaggat tgccgagtcg gatttgctag ttaatgccac cagtgtgggc
     2821 atggatggcc aatcctctcc tgttcctgaa aacatagtct taccagaaac tctcttagtt
     2881 gcagatatca tataccaacc ctttgaaaca ccgtttttga aatgggctag aagtcagggc
     2941 aatccagcag tcaatggtct gggaatgttg ctctatcaag ctgcagaagc ttttcaactg
     3001 tggacaggca aggaaatgcc gacagaagag atttggcagt ctttaacaga aaaataccaa
     3061 taaagaaagg gagactctcc tatgaaaatc agaatcgata ttcctcatca tccttatgat
     3121 attcagattg aaaaaggttg tatggcccag gctggtcagt ggttgcgaga actctggcaa
     3181 ccgcaaaagg tagtcattgt gacagataac catgtagcct ctctctatgc agagaaggtc
     3241 aagctcagcc tagaagatgc tggttttcag gtagctgttt ttgatttctt agaaggtgaa
     3301 gaaagaaaga atttaactac tgttcagaaa gtctatgaat ttctagtcaa gcaaggtctg
     3361 actcgtagcg atggaatcgt tgctcttggt ggtggcgttg ttggggacct ggctggattt
     3421 gtagcctcta cctatatgcg gggtattcac tttgttcaga ttccgactag tttgacagct
     3481 caggttgatt cttctatcgg tggaaagaca ggcgttaaca caccatttgc taaaaatatg
     3541 gtggggacct ttgcccaacc agatggggtt ctgattgatc cacttgttct tgaaaccctc
     3601 ggaaaaagag agttgattga agggatgggt gaagttatca agtatggctt gattgaggat
     3661 ccagaactgt ggactctctt gacggggctg aatggttctg ttgagagcat tttggaacat
     3721 gcagagacct tgattgaaca ttcttgtcag gtgaagcgca agatggtggt tgaagatgag
     3781 ttggacaatg gtattcgtct ttacctcaat tttggccaca ctattggcca tgccatcgaa
     3841 gcgactgccg gttatggcaa ggtcatgcat ggagaggctg ttgccatggg aatggtacag
     3901 atttccaaga ttgctgagga aaaaggcctc atgccagctg gcattaccca atctatcaca
     3961 gagatgtgtc agaaattcgg cttgcctgtt gactatgaaa attgggaagt tgacaagctt
     4021 tatcaggctc ttactcatga caagaaagcg cgtggtaaca ccttgaaatt ggtcttggtg
     4081 ccagagcttg gttcagcgac cattcatcca gtttctctgg aagagatgaa agactacttg
     4141 gtaaaataag gagagtgtat gagatattta actgcaggag aatcacacgg cccccgtcta
     4201 acagctatta ttgagggaat tccagctgga cttccattga cagctgagga tatcaatgag
     4261 gaccttagac gccgtcaggg tggctacggt cgtggtggtc gtatgaagat tgagagtgac
     4321 caggttgtct ttacttcggg cgttcgccac gggaagacga caggggcgcc tattactatg
     4381 gatgtcatca ataaggacca ccagaaatgg ctggacatca tgtctgcgga ggacattgaa
     4441 gaccgcctta aaagcaagcg gaaaattact catcctcgcc caggtcatgc cgatttggtt
     4501 ggggggatta agtaccgttt tgatgatttg cgaaattctt tggagcgttc atcagctcgt
     4561 gaaaccacca tgcgggtggc agttggtgca gtagccaaac gtctcttggc tgagctggat
     4621 atggagattg ccaaccatgt cgtggtcttt ggtggcaagg aaatcgatgt tcctgaaaat
     4681 ctgacagtcg ctgaaattaa gcaaagagct gcccagtctg aagtttctat tgtcaaccaa
     4741 gaacgagaac aggaaatcaa ggactatatt gaccaaatca aacgtgatgg tgataccatc
     4801 ggtggggttg tggagacagt cgtcggaggc gttccagttg gtcttggttc ctatgtccaa
     4861 tgggatagaa aattggatgc aagattggct caagctgttg tctctatcaa tgcctttaaa
     4921 ggggtggaat ttggtcttgg ctttgaggct ggttatcgta aaggcagcca agttatggat
     4981 gaaattctct ggtctaaaga agacggttat actcgccgta ccaataatct aggtggtttt
     5041 gaaggtggta tgactaatgg gcaacccatc gttgttcgtg gggttatgaa acccattcct
     5101 actctttata aacctcttat gagtgtggat atcgaaaccc acgaacctta caaggcaacc
     5161 gtggagagaa gtgatccgac tgctcttcca gctgcaggaa tggtcatgga agcagttgta
     5221 gcaacggttc tggcgcaaga aatcctcgaa aaattctcat cagataatct tgaggaacta
     5281 aaagaagcgg tagccaaaca ccgagactat acaaagaact attaaggagt tcctatggca
     5341 aaaacaatct atatcgcagg tcttgggttg attggagcct ctatggcact tggtatcaaa
     5401 cgcgatcatc cagattatga aattttaggt tataatcgta gtcaagcttc gagagacatc
     5461 gccttgaaag aaggcatgat tgaccgtgca acggatgatt ttgctagttt tgctcctttg
     5521 gcagatgtca ttatcctcag cttgccaatc aaacaaacta ttgctttcat taaggagttg
     5581 gccaatttgg atttgcgaga aggcgttatt atttcagatg ctggttcgac caagtcaacc
     5641 attgtggatg cggcggagca gtatttggct ggcaagtctg ttcgctttgt cggggcccat
     5701 cccatggctg gtagtcacaa gacaggggct gcttcggcag atgtcaatct ttttgaaaat
     5761 gcctattata tctttacacc ttcaagcctg acaagtcagg acacgcttaa ggaaatgaag
     5821 gatctgcttt caggtcttca tgctcgtttt atcgagattg atgccaagga gcatgatcgt
     5881 gtcacttctc agattagcca ttttcctcat attttggctt ctagtctcat ggagcagact
     5941 gcggtctatg ctcaagagca tgagatggca aggcgctttg cggcaggtgg ttttcgagat
     6001 atgacccgaa ttgcggaaag cgagccagga atgtggacct ccattctctt gtccaatagc
     6061 gagaccattc tggatagaat tgaggatttc aaggaacgtt tggaagcgat tggtcaggcc
     6121 attagtaagg gagatgaaga gcaaatttgg aactttttta accaagcgcg tgaacaacgc
     6181 cagaccatgg aaatccataa gcgtggtggt gtggatagct cttacgacct ctatgttgac
     6241 gttcctgatg aagaagatgt catcctgcgg attttggaac tgctacgtgg gacttccttg
     6301 gttaacatcc acatcaacga ggaaaatcgt gaggatattc acggaatcct acaaatttca
     6361 tttaaaaatg ctcaagactt ggaaagagcc gagcatctca taacaaaaaa taccgactat
     6421 acagtcgtca ttaaataagg agaagaacat gtcaaatatt tacgatagtg caaacgaact
     6481 cagtcgcggt ctacgcggat taccagaata caaggctgtt aaagcagcta aagatgcgat
     6541 tgcagcagat gctgaggcaa gcaaaatctt tacagaatat cttgcctttc aagaggaaat
     6601 tcaaaaacta gcacagacag gtcaaatgcc agatgcgtcc ttccaagcta agatggaagg
     6661 ctttggtaaa cagattcaag gaaatagcct cttgtcagaa ttctttacca agcaacaaca
     6721 attggccatt tacctttctg acattgaaaa aattgttttc gaaccagttt cagaattgct
     6781 gaaataagaa aagaactatc ctaaagtcag gaatttttaa ggaatttctg gctttttatg
     6841 ataaaatagg taaaagtatt gcaagtatga ggtccagtat gaaactaaaa acaaacattc
     6901 gccatttaca tggtagtatc cgcgtcccag gtgacaagtc tatcagccac cgttccatta
     6961 tctttggaag tttggctgag ggtgagacca aggtttatga tattctgcga ggtgaagacg
     7021 ttctttcgac catgcaggtt tttcgtgacc ttggtgttga aattgaggat aaagatgggg
     7081 ttattaccgt tcaaggtgta ggcatggctg gcttaaaagc gccgcaaaat gcccttaata
     7141 tgggaaattc tggcacctcg attcgcctga tttcaggtgt ccttgctggt gcagatttcg
     7201 aagtagagat gtttggagat gatagtcttt ccaaacgtcc tatggaccgt gtgacccttc
     7261 cactgaaaaa aatgggcgtc agcatctcag ggcaaactga acgagacttg cctccccttc
     7321 gcttaaaagg gacgaaaaac ctaagaccta ttcattatga gttgccaatt gcctctgccc
     7381 aagtcaagtc agccttgatg tttgcagcct tacaagctaa gggggagtca gttattatcg
     7441 aaaaagagta cacccgtaat catactgaag atatgttgca acaatttggt ggtcatttaa
     7501 gtgtggatgg taagaaaatc acagtccaag ggccacaaaa attgacagga cagaaggtgg
     7561 tcgtaccagg agatatttcc agtgcagcct tttggttagt cgcaggtttg attgctccaa
     7621 attctcgtct agtgctgcag aatgtgggga taaacgaaac tcgcaccggt attattgatg
     7681 tcattcgtgc catgggtgga aaattggaaa taactgaaat cgatccagtc gctaaatctg
     7741 caaccttgat tgttgagtct tctgacttga aaggaacaga gatttgtggc gctttgattc
     7801 cacgtttgat tgatgaattg cctattattg ccctacttgc gacccaagcc caaggtgtaa
     7861 cagttatcaa ggatgctgag gagctcaagg tcaaggaaac agaccgtatt caggttgtgg
     7921 cagacgcctt aaatagtatg ggagcagata ttactcctac ggcagatggg atgattatca
     7981 aaggaaaatc agctcttcac ggtgctagag tcaatacgtt tggtgaccac cgtatcggca
     8041 tgatgacagc tatcgcagcc ctattggttg cagatggaga ggtggagctt gaccgtgcag
     8101 aagccatcaa taccagctat cctagtttct ttgatgattt ggagagcttg attcatggct
     8161 aaggtgttat tagggtttat gggggctggg aaatcgagta ttgcaagagg cttggaccct
     8221 aattaccttg atatggatgc tctgattgag aagcgcctag gtatgtccat tgcgaatttt
     8281 ttcgctgaaa agggagaagc agcctttcgt caggtagaat cagaagtcct agctgattta
     8341 ttacaaagag accaagtcgt gtcaactgga ggaggagtgg ttatttctca gagaaatcgt
     8401 gacttactca agactaatac agataacatc tacctgaaag cagattttga aaccctctac
     8461 ctacgtatcg cagctgataa ggacaatcag cgaccgcttt ttctaaataa tagcaaggaa
     8521 gaactagtag ctatttttca agaaagacag gcttggtatg aggaagtggc tagtcgggtt
     8581 ttggatgtga ccaagctaag cccagaggaa attatagagg aactaagatg aaaattgctt
     8641 atctaggtcc caaaggatca ttttcacacc acgttgtgca gacagctttt cctcatgagg
     8701 aattgcaggc ttttgccaac attacagatg tcatcaaggc ttatgagcaa ggattagtgg
     8761 actattctgt ggtgccagtt gaaaattcta ttgagggtag tgttcatgaa accttggact
     8821 atctttttca tcaggctcac atccaagcag tagcagaaat cgttcagcct attcatcagc
     8881 agttgatggt ggttccaggc catactaaga ttgaaaagat tttttcacat ccacaggcct
     8941 tggctcaagg aaagaaattc atcgatgaac aatatccaga ggctcaaatc gaggtaacag
     9001 ctagtacagc ttatgcggcc cgttttattt ccgaacatcc agatcagccc tttgcagcaa
     9061 ttgcacctag aagttctgct gaagaatatg gattggaact gattgccgag gatattcagg
     9121 aaatggaagc caatttcaca cgtttctggc ttctaggagc tgaaaagcct agtattccct
     9181 tgcaagcaca aactgaaaag atgagtttgg ccttgacatt acctgacaac cttccaggtg
     9241 cactttataa ggccctgtcg acctttgctt ggcgaggaat tgacttgaca aaaattgaaa
     9301 gtcgtccact caagacagca ctgggtgaat actttttcat tatcgatgtg gattataccg
     9361 ataaggactt ggtccacttt gcccaaaaag aattagaagc gattggaatc cagtataaaa
     9421 ttctgggtgc ctatcctatt tatccaatat cagaccatgg aaaggagaga agatgagtaa
     9481 agaaaatccc ttaagtcatc atgagcagtt gcgttatgat tatttgctaa aaaatattca
     9541 ctatctcaat gagagagaaa aaaatgagtt tgtctatttg caagaaaagc taactcttgc
     9601 taggggaaat agtagctcta gcttggaaca agaaagagaa gagcaggttg acttaccaag
     9661 ctatgcgaac cggagtcgct cacaatccaa atcacaagca ctctctttcc ctccaaaaaa
     9721 gaaaagacgg aagctccgtc ttaaacgaat ttttatggtg attttttcac ttttggtctg
     9781 tgtggctttg gccatggtat tcatgttttt gcgtggttac caagatgcta gcgcaaagaa
     9841 aactgctgat gcccgggcag ctcaagtaga agtctttaat ggtcaggaca ctagagatgg
     9901 agttaatatt ttaatcatgg gtactgatgg tcgaatcggc cagaacagtg ttgagacacg
     9961 aactgactct attatggtat taaatgtcgg gggctcagat aagaaaatga agctagtcag
    10021 tttcatgcgt gataatttgg tctatataga tggttatagt caagtgatta acggtagaaa
    10081 acagacagat aacaagttaa acgtagccta cgagttagga gaacaagagg ggcaaaaagg
    10141 ggcagaaatg gttcgccaag tcttgaaaga taattttgac ttggacatta agtactacgc
    10201 cttggttgat ttccaggcct ttgccacagc gattgacacg cttttccctg atggggtgac
    10261 gattgatgct caattttcaa cattgaatgg gcgtccccta acagaagcta cagtcggaga
    10321 tgatttatac gctaccgaga ctgagtctcc aacccaaacc attaaagtcg gaaaacagca
    10381 gatgaatggc tcgaccctgc tcaattatgc tcgtttccgt gatgatgatg aggcggatta
    10441 cggccgtaca aaaagacagc aacaagtttt aacagcaatt ttagagcaaa ttaaagatcc
    10501 cactaaactt ttcactggtt ctgaagctct tggaaaggtt tttgctatga cctcaaccaa
    10561 cgtaccctat actttcctcc taacaaacgg tttatctgtt ttggatggag caaaaaatgg
    10621 tattgaaaaa ttgacgattc cagaactggg tgactgggta gatgcctatg atgtttatgg
    10681 aggcttgggc ttgctggttg atcaaaacaa atatcaaacc aagctcgctc aaatgggctt
    10741 gagataagat aatactcaat gaaaatcaaa gtgcaaatta ggaagctagc cgcaggctgc
    10801 taaaaacaca gttttgaggt tgtagataag actgacgaag tcagttacct atacctacgg
    10861 caaggtgaag ctgacgttgt ttgaagagat tttcgaagag tataagacag aaaaatcaaa
    10921 gtttgatagc tatttggata gcagtcaggc tttgattttt tacagtctgc aatagatttt
    10981 caccccttgt ttgtggtata atgaaacgat acgatagaaa gaataatgaa taatatgact
    11041 gatttaaaag caattcaggc tcgtagtctg gagatggctg aatattttgt ggccttttgt
    11101 aaagaacatg atttgctctg ttatctctgt ggcggaggcg ctattggtgc ccttcgaaac
    11161 aagggattta ttccttggga cgacgaccta gactttttta tgcctcgtaa agattatgag
    11221 aaattagcag aattatggcc tcgttatgca gatgaacgtt atttcttgtc aaagagtcac
    11281 aagaattttg ttgatcgtaa tctttttatt accattcgtg acaaggaaac cacctgtatc
    11341 aagccttatc agcaggattt ggatttgcca catggtctgg ccttggatgt tttgcctttg
    11401 gattattatc cgaaaaatcc agctgagcgg aaaaaacagg ttcgttgggc cttgatttat
    11461 tcactctttt gtgcgcaaac tattccagaa aagcatggtg ctctcatgaa atggggaagt
    11521 cgcattttac tgggtttgac tccaaaatct ctccgttatc gcatctggaa aaaagctgag
    11581 aaagaaatga ctaagtatga tttggctgat tgtgatggca ttacagaatt atgctcaggt
    11641 cctggctaca tgagaaacaa gtacccaatc acatcttttg aagacaatct tttcttgcca
    11701 tttgaaggaa cagagatgcc tattccaatc ggctatgatg tctatctcag aactgctttt
    11761 ggggattata tgacgcctcc accagcagac aagcaggtac cgcatcatga tgctgtcatc
    11821 gctgatatgg ataagtctta tacagaatac aagggagaat atggtggcta agaaaaaaat
    11881 cttatttttt atgtggtctt tttctcttgg aggtggtgca gagaagattc tatcaaccat
    11941 tgtttcaaat ctggatccag aaaagtatga tattgatatt cttgaaatgg agcactttga
    12001 caagggatat gaatctgttc caaagcatgt acgcatttta aaatcccttc aagattatcg
    12061 ccaaaccaga tggttacgag cttttttgtg gagaatgaga atttattttc caagactgac
    12121 tcgtcgtttg cttgtaaaag atgattatga tgttgaagtt tcttttacca ttatgaatcc
    12181 accactgttg ttctctaaaa gaagagaagt caagaagata tcttggattc atggaagtat
    12241 tgaagaactt cttaaggata gctctaaaag agaatcacat agaagccagt tggatgctgc
    12301 gaatacaatt gtagggattt caaaaaagac cagcaattct atcaaggaag tttatccaga
    12361 ttatgcttct aaattacaga caatctacaa tggatatgat tttcagacta ttctagaaaa
    12421 atctcaagag aagatcgata tcgagattgc tcctcaaagt atctgtacta tcggacggat
    12481 tgaggaaaat aagggttctg accgtgtagt ggaagtgata cgattattac accaagaggg
    12541 aaaaaactat catctctatt ttatcggggc tggtgatatg gaagaggaac tgaaaaaacg
    12601 agtcaaagag tatgggattg aggactatgt acatttcctt ggttatcaaa aaaatcctta
    12661 tcagtatcta tctcagacga aagttctttt gtctatgtct aaacaagaag gttttcctgg
    12721 agtgtatgtg gaggccttga gtctgggact cccttttatc tctacggacg ttggaggggc
    12781 tgaggaatta tcccaagaag gacgatttgg acaaatcatt gagagcaatc aagaggcagc
    12841 tcaggcgatt attaattaca tgacttctgc ctcaaacttt gatgtcgatg aggctagcca
    12901 attcattcaa caatttacaa ttacaaaaca aatcgaacaa gtagaaaaac tattagagga
    12961 gtagcatgga aactgcatta attagtgtga ttgtgccagt ctataatgtg gcgcagtacc
    13021 tagaaaaatc gatagcttcc attcagaagc agacctatca aaatctggaa attattcttg
    13081 ttgatgatgg tgcaacagat gaaagtggtc gcttgtgtga ttcaatcgct gaacaagatg
    13141 acagggtgtc agtgcttcat aaaaagaacg aaggattgtc gcaagcacga aatgatggga
    13201 tgaagcaggc tcacggggat tatctgattt ttattgactc agatgattat atccatccag
    13261 aaatgattca gagcttatat gagcaattag ttcaagaaga tgcggatgtt tcgagctgtg
    13321 gtgtcatgaa tgtctatgct aatgatgaaa gcccacagtc agccaatcag gatgactatt
    13381 ttgtctgtga ttctcaaaca tttctaaagg aatacctcat aggtgaaaaa atacctggga
    13441 cgatttgcaa taagctaatc aagagacaga ttgcaactga cctatccttt cctaaggggt
    13501 tgatttacga agatgcctat taccattttg atttaatcaa gttggccaag aagtatgtgg
    13561 ttaatactaa accctattat tactatttcc atagagggga tagtattacg accaaaccct
    13621 atgcagagaa ggatttagcc tatattgata tctaccaaaa gttttataat gaagttgtga
    13681 aaaactatcc tgacttgaaa gaggtcgctt ttttcagatt ggcctatgcc cacttcttta
    13741 ttctggataa gatgttgcta gatgatcagt ataaacagtt tgaagcctat tctcagattc
    13801 atcgtttttt aaaaggccat gcctttgcta tttctaggaa tccaattttc cgtaagggga
    13861 gaagaattag tgctttggcc ctattcataa atatttcctt ataccgattc ttattactga
    13921 aaaatattga aaaatctaaa aaattacatt agaacggggg tgaccaagtg attgatggga
    13981 aacgattatt atttagtttg accatagtca gttatacctt gacgatagta agtggaattg
    14041 tgtatctgtt taataataat aatgttagct tactttctac tttattgttc ttgttggtta
    14101 gtagcttaat tgcttgttgg aatgatatca agtattactt aatccatttt attttctatt
    14161 taaccatttt tgtatttctg gtatcaagac cgaccattga ttattttagg gatggtgctt
    14221 tggataccta tcatccaata gcctatcgtt ttgcctttat agttgttatg gtttcgattc
    14281 tgggcttgac cacaggaggc gtcctggctc gttacttcat agctaggaag aaaataaaag
    14341 tagcaaatat aggaaattct ctaaaagagg tttatatcaa gcggttacgc tttgtatcac
    14401 taggagtttt tcttctaacc tatcctttct atttcattcg gttatttgaa cggctcttgt
    14461 atcgtttgca gacttcctac tatgcctact atgcaaattt tgaaagtaaa ctgccttatt
    14521 ttacctacat tttgtctacc tttacggtct atgcaatgtg tatgtatctg gcaaccaagc
    14581 caaagaaatt gcaggccaca gcagtgcttg tctcctttat tgcagctaat actattcatt
    14641 tggcaattgg gacacgaaat ccctttattt taagtatttt atttgctttt gtttattatt
    14701 ttatgcggga gcaaactgaa aaaggaaaat ggattgggtt taaagaaaag ttagcgattt
    14761 ttgtaggttc tcctattctc atgttagcga tgggagtact taattatgta cgggataatg
    14821 tccaagtttc ccatacaggt ttctgggata tcttacttga ctttatctat aaacaaggga
    14881 ctagttttgg tgttctggct cgaggttttc tatttaacag tagcctccct taccgagatt
    14941 tccgtaattt tacttttggt cctgttcttg attattttgc aagggggagt ttgggagcca
    15001 ttttcggagg aaaagccttt gaacatacaa ccaatagtgt ggaactagct attgatagta
    15061 atagttatgc ccacaatcta tcctatcttg tcttgaacaa ggaatacctg aaagggcatg
    15121 gtatcggaag tagttatatc atggagttgt ataccgacta tggtatgatt ggagtctttc
    15181 tgcttagttt cttactcggc gtattattta tagccatgct gcaagtagcc tatcgctcaa
    15241 ggacaatcct atttgcttta tccctactca tcttgaataa tctattcttt atgccaagaa
    15301 gcagcttttc agaaagtttc ttcaatttat ttacaatgca attctgggga attgttcttg
    15361 tgattatatt tgtagcaaaa atgcttacaa aggaaaacta gtatctacta aacaaaggag
    15421 aaaaaaatca tgtttgaaca ttattcagta gctgatttgt ttgcaaatct ttataaaaaa
    15481 cgaaaagcaa atattttagc tctcatcgct ttatttgctc tcattgctgt accatttaca
    15541 attaaagcag ttaggaataa aaacactgtc aaagatacaa caagttattc aacttatctt
    15601 atctataaaa tcactcctcc agaagattcg gccaaaacga ttttgaatca tcaaattggt
    15661 ggttatagtg atttttatgg gaaattgatt gatggtaatt tgaatggagc ttatcttttc
    15721 aatgatgtag aacccagtga gttgaaaaaa attgccagtg aattagacac gacggaaaca
    15781 accttgaaaa attcaacgaa tgactattgg tggaaaaaat tgaccgtcta ctatatgatt
    15841 gacgatgcag gggttggtgt gaaaattttg acatcaagta aagatgccaa tgacttgtta
    15901 gagaaaaaaa ttgatgggtt gattgagaaa tttaaacatg cttatgcaaa tgtgaaaatt
    15961 gaaaaactgg aaaccatcaa ctctaaagaa ttgaacgcaa atggtgaaac agcgcttggc
    16021 ttaaatgtga aaaatctgat tcttcgttta gttgttattg gagtggtttg tgtgattttg
    16081 gttgtgatgg gaaatgtgtt agtttatctc tttaatccaa caatcaatag agtaggtgat
    16141 ttttctcagt atcaaattga ttttgtaaca gagattacaa caattgctaa cctagcagat
    16201 gttttgtcat acaaaaatac tggacaggaa ttgaccatcg ttagctcaaa taaagctatc
    16261 ctagataaat tgaaacagag tcaagaagct ttaaaaggaa tgcattttgt agatttgcag
    16321 gatgtatcat ctcttttgga aagagataca gtccttcttg ttgaagagta cggagtgact
    16381 cgttataaga aatttgagca aagtcttcaa attctcagaa acttaaatcg ttctatcctc
    16441 ggtgtagcaa cctttaaatt ataagtattc tgatgtataa ggtcttcaaa atcggctaag
    16501 agccgatttt gaaggctttt tctatctgtc tgcagaaatt ttctcttgga gtctcctata
    16561 gaaagaccct agggaaaatc tatccgtata gaggagcctt cttttgataa aatcgtaaaa
    16621 atctagtata atagatagaa ctgaaagtat gaggttacta gcaatgaaaa tgaaacaaat
    16681 tagtgataca actttaaaaa tcacgatgtc tttagaggat ttgatggatc gtggaatgga
    16741 gattgctgac tttctcgttc ctcaagaaaa aacagaagag ttcttttatg ctatcttgga
    16801 tgagctagag atgcctgata gctttctgga tacaggcatg ttgagcttcc gtgtgactcc
    16861 aaaacctgat aaggtagatg tctttgtgac caagtcaaag attgaccaaa atctagattt
    16921 tgaagactta tcggatttgc cagatatgga agaattggct caaatgtctc cagatgaatt
    16981 tatcaaaacc ctggaaaaaa gcatcgcaga caaaaccaag gatgatatcg aagccattca
    17041 atctcttgag caagttgaag ccaaggaaga agaacaagag caggctgaac aagaagctga
    17101 gagtaagaaa gaaccttaca tctactacat cctttctttt gctaagttgg ctgacttggt
    17161 agcttttgcc aagacagtga cttttgaaat ggaaacttct gaactctaca aaatgaacga
    17221 gcgctattat ttgaccattt tagtggatat tgaaaatcat ccaagcccat atccagcttg
    17281 gctgttggcc cgtatgcgcg agtttgcaga cgatagtgat atcagtcgct cagtcttaca
    17341 agagtatggt caagtcttga tgagtcacga tgcagtgctc aatctgcaaa aaatcggcta
    17401 atcctttctg gaaagctatt ttcagatttt aagaagagcg aatcgtctga ttcgtttttt
    17461 ctttttatac tgaaatagtg atttactata ataggaattt tcacaaaatt ctgttataat
    17521 ggctatatta gaaaatttcg aggagataaa gatgacagtt aaaattgctt tactgggatt
    17581 tggtaccgtt gcaagtggtg tgcctttcct cctaaaggaa aatggaggaa aaatcaatca
    17641 atcagcacat tcagatatca aagttgctaa ggtattggtc aaggatgaag atgaaaaaaa
    17701 tcgcttgctt gcagcaggga atgactttaa ctttgtaacc aatgtggatg atattttatc
    17761 agaccaggat attactatcg tagtggaatt gatggggcgt attgagcctg ctaaaacctt
    17821 tatcactcgt gccttggaag ctggaaaaca cgttgttact gctaacaagg accttttagc
    17881 tgtccatggc gcagaattgc tagaaatcgc tcaagctaac aaggtagcac tttactacga
    17941 agcagcagtt gctggtggga ttccaattct tcgtacttta gcaaattcct tggcttctga
    18001 taaaattacg cgcgtgcttg gagtagtcaa cggaacttcc aacttcatgg tgaccaagat
    18061 ggtggaagaa ggctggtctt acgatgatgc tcttgcggaa gcacaacgtc taggatttgc
    18121 agaaagcgat ccgacgaatg acgtagatgg gattgatgca gcctacaaga tggttatttt
    18181 gagccaattt gcctttggca tgaagatcgc ctttgatgat gtagcccaca agggaatccg
    18241 caatatcaca ccagaagacg tagctgtagc tcaagagctt ggttacgtag tgaaattggt
    18301 tggttctatt gaggaaactt cttcaggtat tgctgcagaa gtgactccaa ccttcctacc
    18361 taaagcgcac ccacttgcta gtgtgaatgg cgtaatgaac gctgtctttg tagaatctat
    18421 cggtattggt gagtctatgt actacggacc aggtgcgggt caaaaaccaa ctgcaacaag
    18481 tgttgtagct gatattgtcc gtatcgttcg tcgtttgaat gatggtacta ttggcaaaga
    18541 cttcaacgaa tatagccgtg acttggtctt ggcaaatcct gaagatgtca aagcaaacta
    18601 ctatttctca atcttggctc tagactcaaa aggtcaggtc ttgaagttgg ctgaaatctt
    18661 caatgctcaa gatatttcct ttaagcaaat ccttcaagat ggcaaagagg gtgacaaggc
    18721 gcgtgtcgtt atcatcacac acaagattaa taaagcccag cttgaaaatg tctcagctga
    18781 attgaagaag gtttcagaat tcgacctctt gaataccttc aaggtgctag gagaataaga
    18841 tgaagattat tgtacctgca accagtgcca atatcgggcc aggttttgac tcggtcggtg
    18901 tagctgtaac caagtatctt caaattgagg tctgcgaaga acgagatgag tggctgattg
    18961 aacaccagat tggcaaatgg attccacatg atgagcgtaa tctcttgctc aaaatcgctt
    19021 tacaaattgt accagacttg caaccaagac gcttgaaaat gaccagtgat gtccctttgg
    19081 cgcgcggttt gggttcttcc agctcggtta tcgttgctgg gattgaacta gccaaccaac
    19141 tgggtcaact caacttatca gaccatgaaa aattgcagtt agcgaccaag attgaagggc
    19201 atcctgacaa tgtggctcca gccatttatg gtaatctcgt tattgcaagt tctgttgaag
    19261 ggcaagtctc tgctatcgta gcagactttc cagagtgtga ttttctagct tacattccaa
    19321 actatgaatt acgtactcgc gacagccgta gtgtcttgcc taaaaaattg tcttataagg
    19381 aagctgttgc tgcaagttct atcgccaatg tagcggttgc tgccttgttg gcaggagaca
    19441 tggtgaccgc tgggcaagca atcgagggag atctcttcca tgagcgctat cgtcaggact
    19501 tggtaagaga atttgcgatg attaagcaag tgaccaaaga aaatggggcc tatgcaacct
    19561 acctttctgg tgctgggccg acagttatgg ttctggcttc tcatgacaag atgccaacaa
    19621 ttaaggcaga attggaaaag caacctttca aaggaaaact gcatgacttg agagttgata
    19681 cccaaggtgt ccgtgtagaa gcaaaataaa gaatagaaga taggatgggg aaactcttga
    19741 ccagagggtt tcatatcctt tttgtgaaaa gaagtttata ctcaatgaaa atcaaagagc
    19801 aaactaggaa gctagccgca ggctgctcaa aacagtgttt tgaggttgca gatagaactg
    19861 acgaagtcag taacatacct acggtaaggt gacgctgacg tggtttgaag agattttcga
    19921 agagtattag ttaaaaacgt gataaaggag aaataaagat ggcagaaatt tatctagcag
    19981 gtggttgttt ttggggccta gaggaatatt tttcacgcat ttctggagtg ctagaaacca
    20041 gtgttggcta cgctaatggt caagtcgaaa cgaccaatta ccagttgatc aaggaaacag
    20101 accatgcaga aacggtccaa gtgatttacg atgagaagga ggtgtcactc agagagattt
    20161 tactttatta tttccgagtt atcgatcctc tatctatcaa tcaacaaggg aatgaccgtg
    20221 gtcgccaata tcgaactggg atttattatc aggatgaagc agatttgcca gctatctaca
    20281 cagtggtaca ggagcaggaa cgcatgctgg gtcgaaagat tgcagtagaa gtggagcaat
    20341 tacgccacta cattctggct gaagactacc accaagatta tctcaggaag aatccttcag
    20401 gttactgtca tatcgatgtg accgatgctg ataagccatt gattgatgca gcaaactatg
    20461 aaaagcctag tcaagaggtg ttgaagacca gtctatctga agagtcttat cgtgtcacac
    20521 aagaagctgc tacagaggct ccatttacca atgcctatga ccaaaccttt gaagagggga
    20581 tttatgtaga tattacgaca ggtgagccac tcttttttgc caaggataag tttgcttcag
    20641 gttgtggttg gccaagtttt agccgtccga tttccaaaga gttgattcat tattacaagg
    20701 atctgagcca tggaatggag cgaattgaag ttcgttctcg ttcaggcagc gctcacttgg
    20761 gtcatgtttt cacagatgga ccgcgggagt taggcggcct ccgttactgt atcaattctg
    20821 cttctttacg ctttgtggcc aaggatgaga tggaaaaagc aggatatggc tatctattgc
    20881 cttacttaaa caaataaaac agagagtggg gcttcccact ttcttcattt ctagaatatg
    20941 aatagaaggg atttatgaaa cacctattat cttacttcaa accctacatc aaggaatcaa
    21001 ttttagcccc cttgttcaag ctgttagaag ctgtttttga gctcttggtt cccatggtga
    21061 ttgctgggat tgttgaccaa tctttacctc agggagatca aggtcatctc tggatgcaga
    21121 ttggcctgct ccttatcttt gcagtaattg gcgttttagt ggccttgata gctcaatttt
    21181 actcagcaaa ggcagcagta ggttttgcta aggaattgac aaacgatctt tatcgtcata
    21241 ttctttcctt gcccaaggac agcagagacc gtctgacaac atctagtttg gtcactcgct
    21301 tgacttcgga tacctaccag attcagactg gtatcaatca attcctgcgt ctctttttgc
    21361 gagcgcccat tatcgttttt ggtgccattt ttatggctta tcgaatctca actgagttga
    21421 ctttctggtt cttagtcatg gttgccattt tgaccattgt cattgtaggg ttatctcgat
    21481 tggtcaatcc tctctacagt agtctcagaa agaaaacgga ccaactggtt caggaaacgc
    21541 gccagcaatt gcaagggatg cgggttattc gtgcttttgg tcaagaaaaa cgagagttac
    21601 agatttttca aacccttaac caagtttatg ctagattaca agaaaagaca ggtttctggt
    21661 ctagtttatt aacacctctg acctatctga ttgtcaatgg aactcttctc gttattatct
    21721 ggcaaggcta tatttcaatt caaggaggag tactcagtca aggtgctctc attgctctta
    21781 tcaattacct cttacagatt ttggtggaat tggtcaagct agccatgctg atcaattccc
    21841 tcaaccagtc ctatatctca gccaagagaa tcgaggaggt ctttgcggaa tctcccgaaa
    21901 acatccattc agaattagaa caaaagcaag ttaccagtgg tcgggtttta caagtccaag
    21961 aattgacttt tacctatcct gatgcggccc agccttctct gagagacatt tcctttgata
    22021 tgactcaagg acaaatcctt ggtatcattg gggggactgg ttctggtaaa tcaagcttgg
    22081 tgcaactctt acttggactt tatccagtag acaaggggaa cattgacctt tatcaaaatg
    22141 gacgtagtcc tcttaatttg gagcagtggc ggtcttggat tgcctatgta cctcaaaagg
    22201 tcaaactctt taagggaact attcgttcca acttgacttt aggtttaaat caagaagtat
    22261 ctgaccagaa actctggcag gccttggaga ttgcgcaagc taaggatttt gtcagtgaaa
    22321 aggaaggact tttggatgcc ctagttgagg caggggggcg aaatttctca ggtggacaaa
    22381 aacaaaggtt gtctatcgcc cgagcagtct tgcgccaagc tccgtttatc atcctagatg
    22441 atgcaacctc ggcactggat accattacag agtccaagct cttgaaagct attagagaaa
    22501 attttccaaa cacgagctta attttgatct ctcaacgaac ctcaacttta cagatggcgg
    22561 accagattct cctcttggaa aaaggtgagt tgctagctgt tggcaagcac gatgacttga
    22621 tgaaatccag ccaagtctat cgtgaaatca atgcatccca acatggaaag gaggactaga
    22681 atgaaacgac aaactgtaaa ccagacgctc aaacgtttag ccgtagattt agcaaaccat
    22741 cccttcctcc ttttcctagc ctttctagga actattgccc aagttggctt atcaatttac
    22801 ctacctattc tgattgggca ggtcattgac caagtcctag tggctggttc atcaccagtt
    22861 ttttggcaga tttttctcca gatgctcttg gtggtaatag gaaatactct ggtacaatgg
    22921 gccaatcctc tcctctataa tcgtctaatc ttctcttata ccagagattt gcgagagcga
    22981 atcatccata agctccatcg tttaccgatt gcttttgtag ataggcaagg tagtggagag
    23041 atggttagtc gtgtaaccac ggacatcgaa cagttggcag ctggcttgac catgattttt
    23101 aaccaatttt tcattggtgt tttgatgatt ctggttagta ttctagccat gctccaaatt
    23161 catctcctca tgactctctt agtcttgctg ttgacgccac tgtccatggt gatttcacgc
    23221 tttattgcca agagatccta tcatctcttc cagaagcaaa cagagacgag gggaattcag
    23281 actcagttga ttgaagaatc gcttagccag cagactataa tccagtcctt caatgctcaa
    23341 acagaattta tccaaagatt gcgtgaggct catgacaact actcaggcta ttctcagtca
    23401 gccatctttt attcttcaac ggtcaatcct tcgactcgct ttgtaaatgc actcatttat
    23461 gcccttttag ctggagtagg agcttatcgt atcatgatgg gttcaacctt gaccgtcggt
    23521 cgtttagtga cttttttgaa ctatgttcag caatacacca agccctttaa tgatatttct
    23581 tcagtgctag ctgagttgca aagtgctctg gcttgcgtag agcgtatcta tggagtctta
    23641 gatagccctg aagtggctga aacaggtaag gaagtcttga ccagtgacca agttaaggga
    23701 gctatttcct ttaaacatgt ctcttttggc taccatcctg aaaaaatttt gattaaggac
    23761 ttgtctatcg atattccagc tggtagtaag atagccatcg ttggtccgac aggtgctgga
    23821 aaatcaactc ttatcaatct ccttatgcgt ttttatccca ttagctcggg agatatcttg
    23881 ctggatgggc aatccattta tgattataca cgagcatcat tgagacagca gtttggtatg
    23941 gtgcttcaag aaacctggct cacacaaggg accattcatg ataatattgc ctttggcaat
    24001 cctgaagcca gtcgagagca agtaattgct gctgccaaag cagctaatgc agactttttc
    24061 atccaacagt ttccacaggg atacgatacc aagttggaaa atgctggaga atctctctct
    24121 gtcggccaag ctcagctctt gaccatagcc cgagtctttc tggctattcc aaagattctt
    24181 atcttagacg aggcaacttc ttccattgat acacggacag aagtgctggt acaggatgcc
    24241 tttgcaaaac tcatgaaggg ccgcacaagc ttcatcattg ctcaccgttt gtcaaccatt
    24301 caggatgcgg atttaattct tgtcttagta gatggtgata ttgttgaata tggtaaccat
    24361 caagaactca tggatagaaa gggtaagtat taccaaatgc aaaaagctgc ggcttttagt
    24421 tctgaataag ccattctctt ttgaaagttt atggacgaaa aaagttgcct tcgagtgact
    24481 tttttgttac aatagctaga aaaattgttc actgtaatac tcaatgaaaa tcaaagagca
    24541 aactaggaag ctagccgtag gttgctcaaa acagtgtttt gaggttgcag atagaactga
    24601 cgaagtcagt aaccacacct acggcaaagt gaatttgaag tggtttgaag agagtacaac
    24661 ttgtctttta gaaaaggagc ctataatgaa agtctttcag catgtaaata tcgtgacttg
    24721 tgatcaagat ttccatgttt atcttgatgg aatcttagca gtcaaggatt ctcaaatcgt
    24781 ctatgtcggt caagataagc cagcgttttt agaacaagct gagcagatta tagactatca
    24841 gggagcttgg attatgcctg gtttggtcaa ttgtcacacc cattctgcaa tgacaggtct
    24901 gagagggatc cgagatgaca gcaatctcca tgaatggctc aatgactata tctggccagc
    24961 agaatctgag tttactcccg acatgactac caatgcggtc aaagaagccc taacagagat
    25021 gctccagtca ggaacaacaa cctttaacga tatgtataat cccaatggtg tggatatcca
    25081 gcaaatttat caggtggtga aaacttccaa gatgcgttgt tatttttctc cgactctctt
    25141 ttcttcagag acagaaacaa ctgctgagac tataagcaga actcgatcca tcatagacga
    25201 aatcttaaaa tataaaaatc caaatttcaa ggttatggta gcacctcatt ctccgtatag
    25261 ctgcagtaga gacttgctgg aagcgagttt ggaaatggca aaagagctaa atattccgct
    25321 ccatgtccat gtggcggaga ccaaggagga gtcaggaatt atcctcaaac ggtacggcaa
    25381 acgccccctt gcttttcttg aagaactggg ttatttagat catccgtccg tatttgctca
    25441 cggggtcgaa ttaaacgaga gagaaattga actcttggca tcttctcaag tggctatcgc
    25501 ccacaatcct atcagtaacc tcaaactggc atcaggaatt gctccaatta tccagctcca
    25561 aaaagcggga gtagtagtcg gaattgcgac tgactcggtt gcttccaata acaatctaga
    25621 tatgtttgag gaaggaagga ctgcagctct tcttcagaag atgaaaagtg gggatgccag
    25681 ccagtttcca atcgaaacag ctctcaaggt actgacaatc gaaggggcta aggtccttgg
    25741 aatggaaaat cagataggaa gtctggaagt cggcaagcaa gcagattttc tggtcattca
    25801 accacaaggg aaaattcatc tccaacctca ggaaaatatg ctgtctcacc tggtttatgc
    25861 agttaaatct agtgatgtag atgatgttta tatcgccgga gaacaggttg ttaagcaagg
    25921 tcaagtcctg acagtagaac tttaaaagaa aaatcacgaa aaattttaaa aaaagtttgc
    25981 aaaaatcttg cattcttttt ttgactatgc tatacttata tacggtttaa aaaaactgcc
    26041 taagacagta ggggagctcg actcataaat atcctaccga ggacaaaacg tatcatgtaa
    26101 aaagaagcgt attgtacttt cgtgtctagg tttgggcgcg tttttctttt tgaaaaattc
    26161 cccaagcaaa ataattacgg aggtgaacac actaatgagt gaagcaatta ttgctaaaaa
    26221 agcggaacta gttgacgtag tagctgaaaa aatgaaagct gctgcatcta tcgtcgttgt
    26281 agacgctcgt ggtttgacag ttgagcaaga tacagttctt cgtcgtgagc ttcgtggaag
    26341 cgaagttgag tataaagtta ttaaaaactc aatcttgcgt cgtgcagctg aaaaagctgg
    26401 tcttgaagat cttgcatctg tatttgttgg accatctgca gtagcatttt ctaatgaaga
    26461 tgttatcgca ccagcgaaaa tcttgaacga cttttctaaa aacgctgaag cacttgaaat
    26521 taaaggtggt gcaatcgaag gcgctgtcgc atctaaagaa gagattcttg cacttgcaac
    26581 tcttccaaac cgcgaaggac ttctttctat gctcctttct gtacttcaag cgccagtgcg
    26641 caacgttgct cttgcagtca aagcggttgc agaaagcaaa gaagacgcgg cttaatctta
    26701 agctacacag cgtagcctag ctacgaaaaa aactattata aaatttaaaa cttatttgga
    26761 ggaaataaca atggcattga acattgaaaa cattattgct gaaattaaag aagcttcaat
    26821 ccttgaattg aacgaccttg taaaagctat cgaagaagaa tttggtgtaa ctgcagctgc
    26881 tcctgtagct gttgctgcag ctgatgcagc tgatgctggt gctgctaaag attcattcga
    26941 cgttgaattg acatctgcag gcgacaaaaa agttggcgtt atcaaagttg tacgtgaaat
    27001 cactggtctt ggtcttaaag aagctaaaga acttgttgac ggtgcaccag cacttgttaa
    27061 agaaggcgtt gcaactgcag aagctgaaga aatcaaagct aaattggaag aagctggagc
    27121 ttcagttact cttaaataat agagtatcgc aatttgattg cggaatccct atttaccagt
    27181 ctttgagagc gataagcgat tgatagaaac tgataaattg atttggtttc ctgccaaaaa
    27241 ttctttggca ggatttttgt tttaataaac tttcgggggt agacactaga ttgtctaccc
    27301 ctttttttgt gtttcggagg taattatgca aaaggaagga cagtcatcac gtcaattcat
    27361 gaagagtcat ctcatgacta tcatgggagt tgatattgta aaagcaactc agttagttga
    27421 tgaaatggaa caagtaggtt taatccgatt tgatgaattt ggaaatgttg gaattttagt
    27481 cttggaggga caataatgaa gcgtattacc gctaatcaat atcagacatc agagcgttat
    27541 tataagctcc ccaaactttt atttgagagt gaacggtata agaatatgaa accggaggtt
    27601 aaggtggttt actcagtttt aaaagatcgg ttggagttgt ctttgagcaa aggttggatt
    27661 gatgaggatg ggactattta tttgatttat tccaattcaa atttgatggc acttttaggc
    27721 tgttcaaagt caaaattact ctccatgtga gtttgaagtg acatttttag atgattacca
    27781 taaaaaacat aactacccac tattttacga atcctatctt caaaacgtta tggaattcct
    27841 tgaaagtcaa gacataaaga atggggttga tgcctttgta gatgatcatc aaaatctcgt
    27901 ttttgtttta tatggacaag gctatcgagc cgagggaaaa gagggaatac ttacaaccca
    27961 agtaactgta aaagcttatg atgaagacaa gaaaccgatt aacttcgcaa atttattaga
    28021 ttccttaatc gtgtcagaat atcaaatgga accgaatctt tgggaggtct cctatgattg
    28081 atctctatct aagtaaaaat agccgaagaa atcaacttct tttagacttc ttccaaaact
    28141 atggcatcga ggtatcttgt cattcagttt ctgaaatgac aaaggacaaa ttaattgaga
    28201 tgatgagcta ttcttcagat tgttttgagt ttttatctcc aaatttatta cgttttaaga
    28261 atcgagataa cctaaaatta acagatttca tcgaaatgat attaaaaaat cctgaactaa
    28321 ccatcagact tcctcttgcg gtttcaaata agcgagttta tccaagtctg aatttggaag
    28381 aggctagagc tctattgcca agagatacga aacaattgat ttacatggcg caaacacatt
    28441 atttatctaa ctaaaggaga agcaatatgg ctgaacgatt ttgggagaac ttgtccatta
    28501 ttttggctga aagaaatatc agctggattg agctaaccag aaaaatgttt gcgggagagt
    28561 ttcactatcc aagtgaattg aatcgtttgt atcaaaagat tcgtcactac aagatggaac
    28621 aacgaatgcc tcaaagtcca tgggtagaaa ggattgtgca ggtattagat ttagattatg
    28681 aagatttatt tcggaggtaa ctatgaaaag aataattcca gtttatatat tccaacaagt
    28741 aaatgtccta ttggtatctc tatacttact gaaatttctt tgtatcggtg agttaactat
    28801 actacagatt ctatattgtg cgtcactcat ttctttttta tggatgtatg cccaacgtaa
    28861 acaagcgcat aaggtcaata tgaaattaag gataaaatgg attggtattg gattagccag
    28921 tctactgatt ataagtctat gttttagtct aatccatgcg caagaaagca cgaatcaagc
    28981 aaacttaatt gggcttcaat atcaagttcc ttggttttca tttttattgt tcttaatcaa
    29041 tgcgagtatg gttgaagaat ttctgtatag agaaatttta tggaacttgg ttagaaaatt
    29101 agatattcga gttgctttga caagtgtttt atttgcctta gcacatcatc caggaaccat
    29161 tatagcttgg tgtttgtatg tatcgctggg gatgttttta gggcttgtac gctacaaatt
    29221 ggacttatgg ggcagtatgg ggctacattt ggtgtggaac ctactagttt atagtttgct
    29281 gcttttttaa aataggtaac ctgattttta ggtaacttct aaaactaact tccagttttg
    29341 ggagagagat ggaagttact ttgaaaagtt acggaaacat tattttctat gtgacaacat
    29401 tgtatcattg cttgcatttt actgctggag agagtataat gaatgtggat aaagcactta
    29461 atcccaaaaa tttaaatagg aggagttagc tatggcagaa gaagtattaa atctttaatt
    29521 agtatctgtt caagttgacg aaacagatga agttgatgga atgcgattta gtacattcag
    29581 tacaaaccgt tgcggtaact ggagtgcttt tagttgggaa aattgttaat tcatttaaat
    29641 tgtaaacttt agagattctc tggagttatg gatgtcgttc caatatgtgc acgttggaat
    29701 gttagtgctt atatgggggg aatccaaagg attctccctt tttattttaa taagtctgtc
    29761 tagctataga tatattaagt ttgatagaat ttcttggaga ttttgttatg gattataatt
    29821 tcaatttgga gcatcctttc tttttcacta ataatgatta tagtacagat actagcataa
    29881 agtactaagt aagtctgcct tttaattggc acgaagtaat gaataatgat gagtgggttt
    29941 atcaataccc tattggaaaa tttgttgaaa gacaagggtg gaaaatacac attagttcag
    30001 agtataatag ttcacacgaa ttgttacaag atgtagcaaa aatttgccat gaaatgcgaa
    30061 ttccatttaa acatcttagt acagaagaca aatttatcat gcgaaacggg aaattggtta
    30121 gtcgaggatt ttctggtaaa tttattacat gttatccaaa tcaaaatgaa ttagagtcgg
    30181 ttttgcaaaa gttagaaagt gccttaaagc aatataatgg gccatatatt ttaagcgata
    30241 aacgttggga tgaagtacca atatatctga ggtatggtgt gtttaggccg tcaagggatg
    30301 atgaaaagaa ggttgctatt gatgaattaa ttgttggcga tgaagttgtt aaagatgaac
    30361 gtttaccagt atttaaaatt ccaaaaggta tagtgccccc tgactttttg aataaatggc
    30421 ttgacaagaa agataaaaaa cagggagact ttccctttat tatagataat gcaattagat
    30481 tttcaaacag tggtgggata tataatgcta gactaaaaga agatgggaaa aaaataattt
    30541 taaaagaggc tagaccgtat acaggtctag gatttgatgg tacttattct tcagagagat
    30601 tagcttcgga gtgcaaagca ctaaaaattc taaatgaatg gagtgagacg cctaaaatat
    30661 actggtgcgg taagatctgg gagcacacct tcttaggaat tgaacatatg aagggcgttc
    30721 cactaaatag atgggttacc aataattttc ctttatatga agttgttgat aagaccaaag
    30781 attatctatt gagagtttca aagatagtag aaaaactcat cgatttaacg aataagtttc
    30841 attctgaaaa tgtatatcat caaaatttac atttaggaaa tatcttggtt aaggatgaag
    30901 atgagattag tataatagac tgggaacagg ctgtcttttc gaatgatgaa aaagttgtac
    30961 ataaagttgc agcccctggt tttagagcat ggcgagaaac acttcccagt gagatagatt
    31021 ggtatggtat tagacaaata gctcattatt tatacatgcc actagtaact acatcggatt
    31081 tgacatacaa ctatgtaagt caaaccagga tagaaggaaa aaaactattt gagtctttgg
    31141 gttatacaag agaacatata gattatgtag aaagtttatt gtcatatcta gattctaaat
    31201 gtccacagat tgagaatatt tccaggaaaa aagttttaaa acccatgcat gagattagaa
    31261 ctatcgagag tgagcaagat atacaagatt ttatcataaa agcctttctt ttagtgaact
    31321 gataggtatt ttcttagcaa acgataaagt tttagggccg atacaatcaa ttgcctattc
    31381 attaaataag ataaatacaa ccaaagattt aaggaaaccg tttttaaaat acttaagtgg
    31441 agagaagaat tttatagacg ctgaacatga taataacgga ctgtatactt catcaataga
    31501 tgagatacac atgaaagatg ttgtatattc tattacacca gaaaataaat taagtattga
    31561 cttctcattt aagtcaccat ttagggtatt attaacagga acttctggta gtgggaaaac
    31621 aacgatttta aatttaatta atggttcttt aaagccacaa aaaggttatg taaatttgtt
    31681 atcacatggg aaaaagagtt cagattcaat accaacagtt gatcagacac catatatttt
    31741 tgacactact attcgtgaga acgtaacttt atttcaaaat gaatattttt cagatgatca
    31801 gataattgag gtgttaaaaa aggtaaatct atatgaagaa ttagaaaaga tagatatact
    31861 aaattatcaa tgtggtgaaa atggtagtaa tttgtctgga ggtcaaaaac aaaaaatagc
    31921 tttagctaga gctctgatta gaaataataa agtgtactta tttgacgaaa tatcagctaa
    31981 tttagataat gataattcaa attccataca tgatattctg ttcaatttag gtatttcatt
    32041 tattgaagtt tcacatcatt atgacttaaa tgacaagaga tacactgata tatataaatt
    32101 ggaaaatgga acacttttca aaattaagtg attggaggca agaatatgga taaagattat
    32161 atattaaaag tgaaagggct gtatcatcaa tttttactag gaaataataa aacgttgcaa
    32221 gtgctgaaaa atgtttctct ttctgcttcg agaggagaat ttataagtat tctaggaatt
    32281 agtggttctg gaaagtcaac tttattaaaa tgtatttcta gtttgcttga accaacaagt
    32341 ggggaagtaa ttttaaatgg aatcaacccc tataaaatca gaaatgcaaa attgtcaagt
    32401 ataagacgta acgaagtatc ttttatattt caagcataca atttaatacc ttccctgccg
    32461 gtaatagaaa atatagcact tcctttgcga ttatcacaaa aaaaattaac tattaaaaat
    32521 gtagaaaact tactcaaaag aatgaagttt aatgctggct taaacgattt tgttggaact
    32581 ctgtctggtg gagaacaaca gaaggttgct atagctagag cggttattgc tgatagtgat
    32641 ataatatttg ctgatgagcc aactggggct ttagacagcg tttctcgtga agtaattttt
    32701 gaattattga gagagttagt aggggcgggt aagtgtgtaa ttatggtaac gcacgatata
    32761 gaattggcct cgaaaactga tcgtgcatta atattgaaag atggaaaaat tttcaaagaa
    32821 cttcatagac ctagcgggga agagttgtat aaaatcttag aggtacaatc aactacggag
    32881 gaatagagat gctcagatta gtttactatc aatttttaca taataagaaa caatggttag
    32941 gcgtttcacc agtaattttt gtttcgagtt tagttatggg attggctgtt aatggggtaa
    33001 ttaatgttga gaataattcg caagtatttg tcggacttcc agatcctaaa ccaattttta
    33061 tgtttccgat agtattcgga ggagtaacat tattctttgt gctctctaac ataataaata
    33121 tgttggttga aatttttaga gatgattacg aacttctgga ggtgttggga gcaagtctcc
    33181 ttcaactatc atttcttgtg gggggacaga tttttatcat ttcctcgatt attagtttta
    33241 ttgcatatct atgctctata tttgttacgt caaattatta ttatttttta caatactttt
    33301 tcggggaaaa tatattacct gatatccaat ttcaaacgag tgctgttgga tgtatcatta
    33361 cagtagtgtt gatttcattt ttagcctttc taagtggttg cttttatacg ttcaagaaga
    33421 ttagaaatag gaagagttct aaaataaggc atgttctttc aatagtaaaa agaatactgc
    33481 tattggctgg ttttagtgtt atctggttgc tttctttgca acaaattttc caagatagca
    33541 caattttagc gaaggcccag ataatattca atattgtaat cttagatatt gtgattattt
    33601 atcaattatc tccttttata cagtcatgtt ttatcaaact actttctata attatattta
    33661 gaaataattt tatgttcatt gtttcgaagt ggaatttact atatcgtaag ccttatataa
    33721 aatctatcag tgctgcaatt acaggagcta tattactaat ttctagtttt caaatgattt
    33781 ctcagaatat actatctcaa tttcaagatg acagtgattt agagctaaaa gtggcattta
    33841 ttgtctatgt aggagcacca attttgatag tacttgcaaa tattatttca attgcatttt
    33901 tgtcatcgca tcaagaaagg attgagattc agcaatttga aattttagga acttctaatt
    33961 accagatggt taagattaaa gttggtgagg ctatattttt gacatttgtt acttcattaa
    34021 ttgcattttt acttaacatt aaaattatgg ctttaatata ctactcttta gaggatattt
    34081 taatagatga tatgaatctt ttggggt
//
LOCUS       DBEJAU010000017        33970 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC323 isolate 683620
            SAMN38261939-rid24807223.denovo.017, whole genome shotgun sequence.
ACCESSION   DBEJAU010000017 DBEJAU010000000
VERSION     DBEJAU010000017.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261939
            Sequence Read Archive: SRR26833919
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 33970)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 33970)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576303.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576303.1
            Genome Coverage       :: 154x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/19/2025 01:05:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,121
            CDSs (total)                      :: 2,078
            Genes (coding)                    :: 1,943
            CDSs (with protein)               :: 1,943
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 36
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 72 of 135
            Pseudo Genes (incomplete)         :: 63 of 135
            Pseudo Genes (internal stop)      :: 51 of 135
            Pseudo Genes (multiple problems)  :: 46 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..33970
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261939-rid24807223.denovo.017"
                     /strain="GPSC323"
                     /isolate="683620"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            <1..191
                     /locus_tag="ACL29Z_000879"
     CDS             <1..191
                     /locus_tag="ACL29Z_000879"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=3
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0069211.1"
                     /translation="RGFTHYKYYRANNKKKKCLIDIKHFFLCLPLSKKMIIDIIVNKN
                     PDRFCMIEKVKKTMAENR"
     gene            complement(216..329)
                     /locus_tag="ACL29Z_000880"
                     /pseudo
     CDS             complement(216..329)
                     /locus_tag="ACL29Z_000880"
                     /inference="COORDINATES: protein motif:HMM:NF014566.4"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane glutamate
                     endopeptidase"
     gene            complement(342..815)
                     /locus_tag="ACL29Z_000881"
     CDS             complement(342..815)
                     /locus_tag="ACL29Z_000881"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001246431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0069212.1"
                     /translation="MRNTKKLRQFGIFLLIILLSTYLPQTIGLYVTIILGLGADVYSL
                     ILTMVLVGSFLLLIWRLKKKKMLFIFEKKSWNWSFVFSLFATYVVYQILGNFWARYAH
                     LINHRNIHDEYFTVVLSNGQPTFLSTILSFVLPVIIGPVFEETLDRGYFMNTFFP"
     gene            complement(833..1018)
                     /gene="briC"
                     /locus_tag="ACL29Z_000882"
     CDS             complement(833..1018)
                     /gene="briC"
                     /locus_tag="ACL29Z_000882"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000148168.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biofilm-regulating peptide BriC"
                     /protein_id="HGR0069213.1"
                     /translation="MTGTNTFTVLSTEDLEQTSGGLAVWEDGYSRWLYYREFAPYMRQ
                     GALNSYIDAWKYGFRAG"
     gene            complement(1281..2048)
                     /locus_tag="ACL29Z_000883"
     CDS             complement(1281..2048)
                     /locus_tag="ACL29Z_000883"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001017399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase carboxyl transferase
                     subunit alpha"
                     /protein_id="HGR0069214.1"
                     /translation="MNIAKIVREAREQSRLTTLDFATGIFDEFIQLHGDRSFRDDGAV
                     VGGIGWLGDQAVTVVGIQKGKSLQDKLKRNFGQPHPEGYRKALRLMKQAEKFGRPVVT
                     FINTAGAYPGVGAEERGQGEAIARNLMEMSDLKVPIIAIIIGEGGSGGALALAVADRV
                     WMLENSIYAILSPEGFASILWKDGTRAMEAAELMKITSHELLEMDVVDKVISEIGLSS
                     KELIKSVKKELQTELARLSQKPLEELLEERYQRFRKY"
     gene            complement(2045..2911)
                     /gene="accD"
                     /locus_tag="ACL29Z_000884"
     CDS             complement(2045..2911)
                     /gene="accD"
                     /locus_tag="ACL29Z_000884"
                     /EC_number="6.4.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001173351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009317 - acetyl-CoA carboxylase complex
                     [Evidence IEA];
                     GO_function: GO:0003989 - acetyl-CoA carboxylase activity
                     [Evidence IEA];
                     GO_process: GO:0006633 - fatty acid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase, carboxyltransferase
                     subunit beta"
                     /protein_id="HGR0069215.1"
                     /translation="MALFSKKDKYIRINPNRSVREKPQAKPEVPDELFSQCPGCKHTI
                     YQKDLGSERICPHCSYTFRISAQERLALTIDMGTFKELFTGIESKDPLHFPGYQKKLA
                     SMREKTGLHEAVVTGTALIKGQTVALGIMDSNFIMASMGTVVGEKITRLFEYATVEKL
                     PVVLFTASGGARMQEGIMSLMQMAKISAAVKRHSNVGLFYLTILTDPTTGGVTASFAM
                     EGDIILAEPQSLVGFAGRRVIENTVRESLPEDFQKAEFLLEHGFVDAIVKRRDLPDTI
                     ASLVRLHGGSPR"
     gene            complement(2948..4315)
                     /gene="accC"
                     /locus_tag="ACL29Z_000885"
     CDS             complement(2948..4315)
                     /gene="accC"
                     /locus_tag="ACL29Z_000885"
                     /EC_number="6.3.4.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000488661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009317 - acetyl-CoA carboxylase complex
                     [Evidence IEA];
                     GO_function: GO:0004075 - biotin carboxylase activity
                     [Evidence IEA];
                     GO_function: GO:0016874 - ligase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase biotin carboxylase
                     subunit"
                     /protein_id="HGR0069216.1"
                     /translation="MFRKILIANRGEIAVRIIRAARELGIATVAVYSTADKEALHTLL
                     ADEAVCIGPGKATESYLNINAVLSAAVLTEAEAIHPGFGFLSENSKFATMCEEVGIKF
                     IGPSGHVMDMMGDKINARAQMIKAGVPVIPGSDGEVHNSEEALIVAEKIGYPVMLKAS
                     AGGGGKGIRKVEKPDDLVSAFETASSEAKANYGNGAMYIERVIYPARHIEVQILGDEH
                     GHVIHLGERDCSLQRNNQKVLEESPSIAIGKTLRHEIGAAAVRAAEFVGYENAGTIEF
                     LLDEASSNFYFMEMNTRVQVEHPVTEFVSGVDIVKEQICIAAGQPLSVKQEDIVLRGH
                     AIECRINAENPAFNFAPSPGKITNLYLPSGGVGLRVDSAVYPGYTIPPYYDSMIAKII
                     VHGENRFDALMKMQRALYELEIEGVQTNANFQLDLISDRNVIAGDYDTSFLMETFLPK
                     YQEKE"
     gene            complement(4327..4749)
                     /gene="fabZ"
                     /locus_tag="ACL29Z_000886"
     CDS             complement(4327..4749)
                     /gene="fabZ"
                     /locus_tag="ACL29Z_000886"
                     /EC_number="4.2.1.59"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000565430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016836 - hydro-lyase activity [Evidence
                     IEA];
                     GO_function: GO:0019171 -
                     (3R)-hydroxyacyl-[acyl-carrier-protein] dehydratase
                     activity [Evidence IEA];
                     GO_process: GO:0006633 - fatty acid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="3-hydroxyacyl-ACP dehydratase FabZ"
                     /protein_id="HGR0069217.1"
                     /translation="MIDIQGIKEALPHRYPMLLVDRVLEVSEDTIVAIKNVTINEPFF
                     NGHFPQYPVMPGVLIMEALAQTAGVLELSKPENKGKLVFYAGMDKVKFKKQVVPGDQL
                     VMTATFVKRRGTIAVVEAKAEVDGKLAASGILTFAIGN"
     gene            complement(4746..5231)
                     /gene="accB"
                     /locus_tag="ACL29Z_000887"
     CDS             complement(4746..5231)
                     /gene="accB"
                     /locus_tag="ACL29Z_000887"
                     /EC_number="6.4.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001052236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009317 - acetyl-CoA carboxylase complex
                     [Evidence IEA];
                     GO_function: GO:0003989 - acetyl-CoA carboxylase activity
                     [Evidence IEA];
                     GO_process: GO:0006633 - fatty acid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase biotin carboxyl carrier
                     protein"
                     /protein_id="HGR0069218.1"
                     /translation="MNLNDIKDLMTQFDQSSLREFSYKNGTDELQFSKNEARPVPEVA
                     TQVAPAPVLATPSPVAPTSAPAETVAEEVPAPAEASVATEGNLVESPLVGVVYLAAGP
                     DKPAFVTVGDSVKKGQTLVIIEAMKVMNEIPAPKDGVVTEILVSNEEMVEFGKGLVRI
                     K"
     gene            complement(5234..6469)
                     /gene="fabF"
                     /locus_tag="ACL29Z_000888"
     CDS             complement(5234..6469)
                     /gene="fabF"
                     /locus_tag="ACL29Z_000888"
                     /EC_number="2.3.1.179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000774039.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004315 - 3-oxoacyl-[acyl-carrier-protein]
                     synthase activity [Evidence IEA];
                     GO_process: GO:0006633 - fatty acid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="beta-ketoacyl-ACP synthase II"
                     /protein_id="HGR0069219.1"
                     /translation="MKLNRVVVTGYGVTSPIGNTPEEFWNSLATGKIGIGGITKFDHS
                     DFDVHNAAEIQDFPFDKYFVKKDTNRFDNYSLYALYAAQEAVNHANLDVEALNRDRFG
                     VIVASGIGGIKEIEDQVLRLHEKGPKRVKPMTLPKALPNMASGNVAMRFGANGVCKSI
                     NTACSSSNDAIGDAFRSIKFGFQDVMLVGGTEASITPFAIAGFQALTALSTTEDPTRA
                     SIPFDKDRNGFVMGEGSGMLVLESLEHAEKRGATILAEVVGYGNTCDAYHMTSPHPEG
                     QGAIKAIKLALEEAEISPEQVAYVNAHGTSTPANEKGESGAIVAVLGKEVPVSSTKSF
                     TGHLLGAAGAVEAIVTIEAMRHNFVPMTAGTSEVSDYIEANVVYGQGLEKEIPYAISN
                     TFGFGGHNAVLAFKRWENR"
     gene            complement(6491..7222)
                     /gene="fabG"
                     /locus_tag="ACL29Z_000889"
     CDS             complement(6491..7222)
                     /gene="fabG"
                     /locus_tag="ACL29Z_000889"
                     /EC_number="1.1.1.100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004316 - 3-oxoacyl-[acyl-carrier-protein]
                     reductase (NADPH) activity [Evidence IEA];
                     GO_function: GO:0051287 - NAD binding [Evidence IEA];
                     GO_process: GO:0006633 - fatty acid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="3-oxoacyl-[acyl-carrier-protein] reductase"
                     /protein_id="HGR0069220.1"
                     /translation="MKLEHKNIFITGSSRGIGLAIAHKFAQAGANIVLNSRGAISEEL
                     LAEFSNYGIKVVPISGDVSDFADAKRMIDQAIVELGSVDVLVNNAGITQDTLMLKMTE
                     ADFEKVLKVNLTGAFNMTQSVLKPMMKAREGAIINMSSVVGLMGNIGQANYAASKAGL
                     IGFTKSVAREVASRNIRVNVIAPGMIESDMTAILSDKIKEATLAQIPMKEFGQAEQVA
                     DLTVFLAGQDYLTGQVVAIDGGLSM"
     gene            complement(7256..8176)
                     /gene="fabD"
                     /locus_tag="ACL29Z_000890"
     CDS             complement(7256..8176)
                     /gene="fabD"
                     /locus_tag="ACL29Z_000890"
                     /EC_number="2.3.1.39"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000167658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004314 - [acyl-carrier-protein]
                     S-malonyltransferase activity [Evidence IEA];
                     GO_process: GO:0006633 - fatty acid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ACP S-malonyltransferase"
                     /protein_id="HGR0069221.1"
                     /translation="MTKTAFLFAGQGAQYLGMGRDFYDQYPIVKETIDRASQVLGYDL
                     RYLIDTEEDKLNQTRYTQPAILATSVAIYRLLQEKGYQPDMVAGLSLGEYSALVASGA
                     LDFEDAVALVAKRGAYMEEAAPADSGKMVAVLNTPVEVIEEACQKASELGVVTPANYN
                     TPAQIVIAGEVVAVDRAVELLQEAGAKRLIPLKVSGPFHTALLEPASQKLAETLAQVS
                     FSDFTCPLVGNTEAAVMQKEDIAQLLTRQVKEPVRFYESIGVMQEAGISNFIEIGPGK
                     VLSGFVKKIDRTAHLAHVEDQASLVALLEK"
     gene            complement(8169..9143)
                     /gene="fabK"
                     /locus_tag="ACL29Z_000891"
     CDS             complement(8169..9143)
                     /gene="fabK"
                     /locus_tag="ACL29Z_000891"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002896881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0018580 - nitronate monooxygenase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="enoyl-[acyl-carrier-protein] reductase FabK"
                     /protein_id="HGR0069222.1"
                     /translation="MKTRITELLKIDYPIFQGGMAWVADGDLAGAVSKAGGLGIIGGG
                     NAPKEVVKANIDKIKSLTDKPFGVNIMLLSPFVEDIVDLVIEEGVKVVTTGAGNPSKY
                     MERFHEAGIIVIPVVPSVALAKRMEKIGADAVIAEGMEAGGHIGKLTTMTLVRQVATA
                     VSIPVIAAGGIADGEGAAAGFMLGAEAVQVGTRFVVAKESNAHPNYKEKILKARDIDT
                     TISAQHFGHAVRAIKNQLTRDFELAEKDAFKQEDPDLEIFEQMGAGALAKAVVHGDVE
                     GGSVMAGQIAGLVSKEETAEEILKDLYYGAAKKIQEEASRWAGVVRND"
     gene            complement(9262..9486)
                     /locus_tag="ACL29Z_000892"
     CDS             complement(9262..9486)
                     /locus_tag="ACL29Z_000892"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002938891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000035 - acyl binding [Evidence IEA];
                     GO_function: GO:0000036 - acyl carrier activity [Evidence
                     IEA];
                     GO_process: GO:0009245 - lipid A biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acyl carrier protein"
                     /protein_id="HGR0069223.1"
                     /translation="MAVFEKVQEIIVEELGKDASEVTLESTFDDLDADSLDLFQVISE
                     IEDAFDIQIEAENDLKTVGDLVAYVEEQAK"
     gene            complement(9546..10520)
                     /locus_tag="ACL29Z_000893"
     CDS             complement(9546..10520)
                     /locus_tag="ACL29Z_000893"
                     /EC_number="2.3.1.180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262906.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004315 - 3-oxoacyl-[acyl-carrier-protein]
                     synthase activity [Evidence IEA];
                     GO_function: GO:0016746 - acyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0033818 -
                     beta-ketoacyl-acyl-carrier-protein synthase III activity
                     [Evidence IEA];
                     GO_process: GO:0006633 - fatty acid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="beta-ketoacyl-ACP synthase III"
                     /protein_id="HGR0069224.1"
                     /translation="MAFAKISQVAHYVPEQVVTNHDLAQIMDTNDEWISSRTGIRQRH
                     ISRTESTSDLATEVAKKLMAKAGITGEELDFIILATITPDSMMPSTAARVQANIGANK
                     AFAFDLTAACSGFVFALSTAEKFIASGRFQKGLVIGSETLSKAVDWSDRSTAVLFGDG
                     AGGVLLEASEQEHFLAESLNSDGSRSECLTYGHSGLHSPFSDQESADSFLKMDGRTVF
                     DFAIRDVAKSIKQTIDESPIEVTDLDYLLLHQANDRILDKMARKIGVDRAKLPANMME
                     YGNTSAASIPILLSECVEQGLIPLDGSQTVLLSGFGGGLTWGTLILTI"
     gene            complement(10520..10954)
                     /locus_tag="ACL29Z_000894"
     CDS             complement(10520..10954)
                     /locus_tag="ACL29Z_000894"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520594.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family winged helix-turn-helix
                     transcriptional regulator"
                     /protein_id="HGR0069225.1"
                     /translation="MDYQRINEYLTSIFNNVLVIEEVNLRGSRFKDISIKEMHTIDVI
                     GKAPDVTPSQVSKELMVTLGTVTTSLNNLERKGYIERVRSEQDRRVVHLHLTKKGRLI
                     HRLHKRFHKAMVEKIIDGMSEEEIAVMGKGLTNLYQFLEDLK"
     gene            complement(11048..11833)
                     /locus_tag="ACL29Z_000895"
     CDS             complement(11048..11833)
                     /locus_tag="ACL29Z_000895"
                     /EC_number="4.2.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="enoyl-CoA hydratase"
                     /protein_id="HGR0069226.1"
                     /translation="MEHIIYQLEEDLAILTLNRPEVANGFHIPMCEEILEALTLAEEN
                     PAVHFILINANGKVFSVGGDLVEMKRAVDEDDIPSLTKIAELVNTISYKIKQIAKPVL
                     MEVDGAVAGAAANMAVAADFCLATDKAKFIQAFVGVGLAPDAGGIHLLSRSIGVTRAA
                     QLAMTGEALTAEKALEWGLVYRVSEAEKLEKTREQLLKKLRRASSNSYAAIKKLVWES
                     QFKDWQGYATLELNLQKSLAQTEDFKEGVRAHSERRRPKFTGK"
     gene            12158..13522
                     /locus_tag="ACL29Z_000896"
     CDS             12158..13522
                     /locus_tag="ACL29Z_000896"
                     /EC_number="2.7.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004251870.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004072 - aspartate kinase activity
                     [Evidence IEA];
                     GO_process: GO:0009089 - lysine biosynthetic process via
                     diaminopimelate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate kinase"
                     /protein_id="HGR0069227.1"
                     /translation="MKVVKFGGSSLASASQLEKVLNIVKSDSERRFVVVSAPGKRNAE
                     DTKVTDALIKYYRDYVAGNDISKSQSWIIDRYAAMVSELGLKPAVLEKISKSIHALAT
                     LPIEENEFLYDTFLAAGENNNAKLIAAYFNQNGIDARYMHPREAGIVVTSEPGHARII
                     PSSYDKIEELTNTNEVLVIPGFFGVTKENQICTFSRGGSDVTGSIIAAGVKADLYENF
                     TDVDGIFAAHPGIIHQPHSIPELTYREMRELAYAGFSVLHDEALLPAYRGKIPLVIKN
                     TNNPDHPGTRIVLKHSNDEFPVVGIAGDSGFVSINMSKYLMNREVGFGRKVLQILEEL
                     NIGWEHMPTGIDDLSIILRSRQLTPIKEEEILRQLVQKAKVDHAEIEHDLSIIMIVGE
                     KMKSHIGVTATATRALSENKINIQMMSQGSSEVSIMFVVNKDQEKAAIKALYNAFFGE
                     SKED"
     gene            13525..13896
                     /locus_tag="ACL29Z_000897"
     CDS             13525..13896
                     /locus_tag="ACL29Z_000897"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000079352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF956 family protein"
                     /protein_id="HGR0069228.1"
                     /translation="MAQSLNKTVLLSTTGTSYLSIAGKVGKFLVGDQALEFYPDVNVE
                     QFIQIPWSHINQIGANVTGRKISRHFEVFTDKGKFLFASKDSGAILKIAREKLGNDKV
                     VKLPTLIQTISQKFKNLFAKK"
     gene            14110..15384
                     /gene="serS"
                     /locus_tag="ACL29Z_000898"
     CDS             14110..15384
                     /gene="serS"
                     /locus_tag="ACL29Z_000898"
                     /EC_number="6.1.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000884256.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004828 - serine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006434 - seryl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="serine--tRNA ligase"
                     /protein_id="HGR0069229.1"
                     /translation="MLDIKRIRTDFEAVAEKLATRGVDAAVLNEMKEIDAKRRNILIK
                     VETLKAERNTVSAEIAQAKRNKENTDDKIAAMQNLSAEIKALDAELAEIDAKLTEFTT
                     TLPNIPADSVPVGADEDDNVEVRRWGTPREFDFEPKAHWDLGEDLGILDWERGGKVTG
                     ARFLFYKGLGARLERAIYNFMLDEHGKEGYTEVITPYIVNHDSMFGTGQYPKFKEDTF
                     ELSDTNFVLIPTAEVPLTNYYRDEILDGKDLPIYFTAMSPSFRSEAGSAGRDTRGLIR
                     LHQFHKVEMVKFAKPEESYEELEKMTANAENILQKLNLPYRVVALSTGDMGFSATKTY
                     DLEVWIPAQNNYREISSCSNTEDFQARRAQIRYRDEADGKVKLLHTLNGSGLAVGRTV
                     AAILENYQNEDGSVTIPEALRPYMGGAEVIKP"
     gene            complement(15409..16308)
                     /locus_tag="ACL29Z_000899"
     CDS             complement(15409..16308)
                     /locus_tag="ACL29Z_000899"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000735961.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TDT family transporter"
                     /protein_id="HGR0069230.1"
                     /translation="MKKLPLVFSGCLLGLAGAGNLILDTLPVLSHLFSLTGLVLWIYF
                     LILHLFNWKETKQELTKPPLLSGMATFPMAGMILSTYVFRVFSYLPLVAQGIWWFSFL
                     LDLTLIAGFTIKFACPGRRVHATPSWTVLYVGIAVAALTYPLVGIIEIAYATLSFGFL
                     LTFYLYPLIYSDLKKHPLPLALLGQEGIYCAPFSLLLASLVRVGGTSLPTWGLIVMIL
                     ASQSFFFFVLTRLPNILKQGFQPAFSALTFPTIITATSLKMAQGILKLPFLDYLVLAE
                     TIICLTILFFVLGAYLIWLRKKV"
     gene            complement(16418..16966)
                     /locus_tag="ACL29Z_000900"
     CDS             complement(16418..16966)
                     /locus_tag="ACL29Z_000900"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000206764.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carboxymuconolactone decarboxylase family
                     protein"
                     /protein_id="HGR0069231.1"
                     /translation="MTTFTIHTVESAPAEVKEILETVEKDNNGYIPNLIGLLANAPTV
                     LEAYQIVSSIHRRNSLTPVEREVVQITAAVTNGCAFCVAGHTAFSIKQIQMNDDLIQA
                     LRNRTPIETDPKLDTLAKFTLAVINTKGRVGDEALSEFLEAGYTQQNALDVVFGVSLA
                     ILCNYANNLANTPINPELQPYA"
     gene            complement(17184..18506)
                     /locus_tag="ACL29Z_000901"
     CDS             complement(17184..18506)
                     /locus_tag="ACL29Z_000901"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0005283 - amino acid:sodium symporter
                     activity [Evidence IEA];
                     GO_function: GO:0015293 - symporter activity [Evidence
                     IEA];
                     GO_process: GO:0006814 - sodium ion transport [Evidence
                     IEA];
                     GO_process: GO:0006865 - amino acid transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alanine/glycine:cation symporter family protein"
                     /protein_id="HGR0069232.1"
                     /translation="MLELLKSIDDFAWGPPLLILLVGTGIYLTMRLGLLQVLRLPKAF
                     QLIFIQDKGHGDVSSFAALCTALASTVGTGNIIGVATAIKVGGPGALFWMWMAAFFGM
                     ATKYAEGLLAIKYRTKDDHGAVAGGPMHYILLGMGEKWRPLAVLFAVAGVLVALLGIG
                     TFTQVNSITESIQNTTTISPAITALVLSVFVAIAVFGGLKSISKVSTTVVPFMAIIYI
                     LGTLTVIFFNIGKIPGTIALVFTSAFSPLAAVGGFAGASVRMAIQNGVARGVFSNESG
                     LGSAPIAAAAAKTNEPVEQGLISMTGTFIDTLIICTLTGLTILVTGVWSGDLNGVALT
                     QSAFSTVFSHFGPALLTIFLVLFAFTTILGWNYYGERCFEFLFGVRFIWLYRVVFVLM
                     VLLGGFIELDMVWIIADIVNALMALPNLIALLVLSPVVIAETKKYFDK"
     regulatory      complement(18597..18685)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00504"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="glycine riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="glycine"
                     /db_xref="RFAM:RF00504"
     gene            complement(18849..21185)
                     /locus_tag="ACL29Z_000902"
     CDS             complement(18849..21185)
                     /locus_tag="ACL29Z_000902"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001035046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease MutS2"
                     /protein_id="HGR0069233.1"
                     /translation="MNKKILETLEFDKVKALFEPHLLTEQGLEQLRQLAPTAKADKIK
                     QAFAEMKEMQALFVEQPHFTILSTKEIAGVCKRLEMGADLNIEEFLLLKRVLLASREL
                     QSFYANLENVSLEELALWFEKLHDFPQLQGNLQAFNDAGFIENFASEELARIRRKIHD
                     SESQVRDVLQDLLKQKAQMLTEGIVASRNGRKVLPVKNTYRNKIAGVVHDISASGNTV
                     YIEPREVVKLSEEIASLRADERYEMLRILQEISERVRPHAAEIANDAWIIGHLDLIRA
                     KVRFIQERQAVVPQLSENQEIQLLHVCHPLVKNAVANDVYFGQDLTAIVITGPNTGGK
                     TIMLKTLGLTQVMAQSGLPILADKGSRVGIFEEIFADIGDEQSIEQSLSTFSSHMTNI
                     VDILGKVNQHSLLLLDELGAGTDPQEGAALAMAILEDLRLRQIKTMATTHYPELKAYG
                     IETAFVQNASMEFDTATLRPTYRFMQGVPGRSNAFEIAKRLGLSEVIVGDASQQIDQD
                     NDVNRIIEQLEEQTLESRKRLDNIREVEQENLKMNRALKKLYNELNREKETELNKARE
                     QAAEIVDMALSESDQILKNLHSKSQLKPHEIIEAKAKLKKLAPEKVDLSKNKVLQKAK
                     KKRAPKVGDDIVVLSYGQRGTLTSQLKDGRWEAQVGLIKMTLEEKEFDLVQAQQEKPV
                     KKKQVNVVKRTSGRGPQARLDLRGKRYEEAMNELDAFIDQALLNNMAQVDIIHGIGTG
                     VIREGVTKYLQRNKHVKSFGYAPQNAGGSGATIVTFKG"
     gene            complement(21289..21837)
                     /locus_tag="ACL29Z_000903"
     CDS             complement(21289..21837)
                     /locus_tag="ACL29Z_000903"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000622948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0009403 - toxin biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="CvpA family protein"
                     /protein_id="HGR0069234.1"
                     /translation="MISFLLLLVLVWGFYIGYRRGLLLQIYYLISAMASAFMAGQFYK
                     GLGEQFHLLLPYANSQEGQGTFFFPSDQLFQLDKVFYAGIGYLLVFGIVYSIGRLLGL
                     LLHLIPSKKLGGKLFQVSAGILSMLVTLFVLQMALTILATIPMAVIQNPLEKSIVAKH
                     IIQSIPITTSWLKQIWVTNLIG"
     gene            complement(21834..22136)
                     /gene="zapA"
                     /locus_tag="ACL29Z_000904"
     CDS             complement(21834..22136)
                     /gene="zapA"
                     /locus_tag="ACL29Z_000904"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006150060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0051301 - cell division [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein ZapA"
                     /protein_id="HGR0069235.1"
                     /translation="MANLNRFKFTFGKKSLTLTSEHDNLFMEEIAKVATEKYQAIKEQ
                     MPSADDETIALLLAVNCLSTQLSREIEFDDKEQELEELRHKLVTCKQEQSKIEDSL"
     gene            22223..23104
                     /gene="rnhC"
                     /locus_tag="ACL29Z_000905"
     CDS             22223..23104
                     /gene="rnhC"
                     /locus_tag="ACL29Z_000905"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000146880.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004523 - RNA-DNA hybrid ribonuclease
                     activity [Evidence IEA];
                     GO_process: GO:0006401 - RNA catabolic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease HIII"
                     /protein_id="HGR0069236.1"
                     /translation="MASITLTPSEKDIQAFLEHYQTSLAPSKNPYIRYFLKLPQATVS
                     IYTSGKILLQGEGAEKYASFFGYQAVEQTSGQNLPLIGTDEVGNGSYFGGLAVVAAFV
                     TPDQHDFLRKLGVGDSKTLTDQKIRQIAPILKEKIQHQALLLSPSKYNEVIGDRYNAV
                     SVKVALHNQAIYLLLQKGVQPEKIVIDAFTSAKNYDKYLAQEANRFSNPISLEEKAEG
                     KYLSVAVSSVIARDLFLENLENLGRELGYQLPSGAGTASDKVASQILQAYGMQGLNFC
                     AKLHFKNTEKAKKRLER"
     gene            23108..23722
                     /gene="lepB"
                     /locus_tag="ACL29Z_000906"
     CDS             23108..23722
                     /gene="lepB"
                     /locus_tag="ACL29Z_000906"
                     /EC_number="3.4.21.89"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001048155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0004252 - serine-type endopeptidase
                     activity [Evidence IEA];
                     GO_process: GO:0006465 - signal peptide processing
                     [Evidence IEA];
                     GO_process: GO:0009306 - protein secretion [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase I"
                     /protein_id="HGR0069237.1"
                     /translation="MNSFKNFLKEWGLFLLILSLLALSRIFFWSNVRVEGHSMDPTLA
                     DGEILFVVKHLPIDRFDIVVAHEEDGNKDIVKRVIGMPGDTIRYENDKLYINDKETDE
                     PYLADYIKRFKDDKLQSTYSGKGFEGNKGTFFRSIAQKAQAFTVDVNYNTNFSFTVPE
                     GEYLLLGDDRLVSSDSRHVGTFKAKDITGEAKFRFWPITRIGTF"
     gene            23956..26322
                     /locus_tag="ACL29Z_000907"
     CDS             23956..26322
                     /locus_tag="ACL29Z_000907"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000454449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0043139 - 5'-3' DNA helicase activity
                     [Evidence IEA];
                     GO_process: GO:0032508 - DNA duplex unwinding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent RecD-like DNA helicase"
                     /protein_id="HGR0069238.1"
                     /translation="MEVYFSGTIERIIFENPSNFYRILLLEIDDTDAEDFDDFEIIVT
                     GTMADVIEGEDYTFWGQIVQHSKYGEQLQISRYDRAKPTSKGLVKYFSSSHFKGIGLK
                     TAQKIVDTYGENTIDEILQHPEKLEGIAGLSAKNREAFVSTLRLNYGTEMVLAKLANY
                     GIPNKLAFQIQDFYKEETLDVVENYPYQLVEDIKGLGFTIADQLAEELGIESQAPERF
                     RAGLVHSLFQACMETGDTYVEARDLLEQTLTLLESSRPVELDPSQVAQELSYLIEEDK
                     VQQIDTKIFDNSLFFAEEGIRSHLVRILEKGEQKSHDLETIQKHITTIEEELGIEYDN
                     IQKQAICDAIQNKVFILTGGPGTGKTTVINGIIAVYALLEGLDLRKKSNLPILLAAPT
                     GRAARRMNELTGLPSATIHRHLGMTGDDDTSHLEDYLDADFIIVDECSMVDTWLANQL
                     FSNISSNSKILIVGDSDQLPSVSPGQVLADLLHIPLIPQTRLEKIYRQSKESTIVTLA
                     SQIRQGILPADFTQKKADRSYFEIASGHIPATIEKILGAALRNGIPARDIQVLAPMYR
                     GTAGIDAINQLMQDLLNPPQKDQLSFEAPQCHYRKRDKVIHLVNDAEINVFNGDLGAI
                     TDLIPGKYTESKQDEIVIDFDGNEVSYPRNEWYKIRLAYAMSIHKSQGSEFPVVILPI
                     TSASRRMLERNLIYTAITRAKSKLILLGELQAFDYATQHIGTARKTYLIERFSDLLEN
                     VEEKQQAVSETVTSSASEQSYILTEENWDSIPAMIGITDTDLKEIFGK"
     gene            complement(26370..27653)
                     /gene="tig"
                     /locus_tag="ACL29Z_000908"
     CDS             complement(26370..27653)
                     /gene="tig"
                     /locus_tag="ACL29Z_000908"
                     /EC_number="5.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005854 - nascent polypeptide-associated
                     complex [Evidence IEA];
                     GO_function: GO:0003755 - peptidyl-prolyl cis-trans
                     isomerase activity [Evidence IEA];
                     GO_function: GO:0051082 - unfolded protein binding
                     [Evidence IEA];
                     GO_process: GO:0015031 - protein transport [Evidence IEA];
                     GO_process: GO:0051083 - 'de novo' cotranslational protein
                     folding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="trigger factor"
                     /protein_id="HGR0069239.1"
                     /translation="MSVSFENKETNRGVLTFTISQDQIKPELDRVFKSVKKSLNVPGF
                     RKGHLPRPIFDKKFGEESLYQDVMNALLPNAYEAAVKEAGLEVVAQPKIDVTSMEKGQ
                     DWVIAAEVVTKPEVKLGDYKNLEVSVDVEKEVTDADVEERIERERNNLAELVIKEAAA
                     ENGDTVVIDFVGSIDGVEFDGGKGENFSLGLGSGQFIPGFEDQLVGHSAGETVDVIVT
                     FPEDYQAEDLAGKEAKFVTTIHEVKAKEVPALDDELAKDIDEEVETLADLKEKYRKEL
                     AAAKEEAYKDAVEGAAIDTAVENAEIVELPEEMIHEEVHRSVNEFLGNLQRQGINPDM
                     YFQITGTTQEDLHNQYQAEAESRTKTNLVIEAVAKAEGFDASEEEIQKEVEQLAADYN
                     MEVAQVQNLLSADMLKHDITIKKAVELITSTATVK"
     gene            complement(28407..29543)
                     /locus_tag="ACL29Z_000909"
     CDS             complement(28407..29543)
                     /locus_tag="ACL29Z_000909"
                     /EC_number="1.1.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000682970.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannitol-1-phosphate 5-dehydrogenase"
                     /protein_id="HGR0069240.1"
                     /translation="MKHSVHFGAGNIGRGFIGEILFKNGFHIDFVDVNNQIIHALNEK
                     GKYEIEIAQKGQSRIEVTNVAGINSKEHPEQVIEAIQKTDIITTAIGPNILPFIAELL
                     AKGIEARRVAGNTQVLDVMACENMIGGSQFLYQEVKKYLSPEGLTFADNYIGFPNAAV
                     DRIVPAQSHEDSLFVVVEPFNEWVVETKRLKNPDLRLKDVHYEEDLEPFIERKLFSVN
                     SGHATSAYIGAHYGAKTILEALQNPNIKSRIESVLAEIRSLLIAKWNFDKKELENYHK
                     VIIERFENPFIVDEVSRVARTPIRKLGYNERFIRPIRELKELSLSYKNLLKTVGYAFD
                     YRDVNDEESIRLGELLAKQSVKDVVIQVTGLDDQELIDQIVEYI"
     gene            complement(29605..30042)
                     /locus_tag="ACL29Z_000910"
     CDS             complement(29605..30042)
                     /locus_tag="ACL29Z_000910"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HGR0069241.1"
                     /translation="MKLEKHLIKLNKQFSNKEEAICYCGQVLYEGGYVNEDYIEAMIE
                     RDKELSVYMGNFIAIPHGTDAAKNDVLKSGITVVQVPRGVDFGNVSNPQVATVLFGIA
                     GIGNEHLEIIQKISIFCADVDNVLKLADAQSKEEVLRLFDAVE"
     gene            complement(30044..31999)
                     /locus_tag="ACL29Z_000911"
     CDS             complement(30044..31999)
                     /locus_tag="ACL29Z_000911"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866831.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HGR0069242.1"
                     /translation="MLLTKREEQLLKAFLHVGKLSMQDMTEILQVSSRTIYRTLSDLT
                     DSMEQYGIEITKHGKYYILTGELDDLPTELEVLVEYSPQERQELITYRLLTESGFVTN
                     EALQECTKVSNVTIIQDISDIDKRLLDFDLKIERQKGYRISGDSVGKRRFLAILLTNC
                     ISVADFSTGNFGSFDILEADRTRLASQIVNKQLSGFPDMDARMKMFFAILLSLIGQEQ
                     NIENSPNTSKQALEISQKIFQAYSKQTAQFYSIQEIIYFASILDELIIKRQDNPLFTE
                     KFDGEFFYNISNLIDTVSMYTKIDFFKDKVLFNFLFHHIRLSLGVPILFQGENLPESV
                     QILVERNKFLYTVISLLVNDIFPKYLHTEYEYGMIALHFISSLGRSPEIYPVRVLLLT
                     DERRVTRDLLVSKIKSVAPFVELIDIQSLVDYHSIDLSQYDYILSTKPLTNQEIDVIS
                     SFPTVKELFELQERLQYVQAHRTIVARDAIAPEKSYDLQDYLISSSQLLSQFELVQLE
                     NNQSFEHTVEQIIQYQKNVSDRDYLTRKLLSHFQNSPMAIPNTGLVLLHSQSSKVTTN
                     SFTMFELKLPISALSMKREEEEVKRCLLMLMSKEASEEARDLMTAISQSIIENHLYTE
                     IYKTGNQSIIYQMLNTIFNEKIKKLEN"
     gene            complement(32023..33792)
                     /locus_tag="ACL29Z_000912"
     CDS             complement(32023..33792)
                     /locus_tag="ACL29Z_000912"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000391672.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannitol-specific transporter subunit IIBC"
                     /protein_id="HGR0069243.1"
                     /translation="MEEKVSLKVRVQKLGTSLSNMVMPNIGAFIAWGVLTALFIADGY
                     LPNEQLATVVGPMLTYLLPILIGYTGGYMIHGQRGAVVGAIATVGAITGSSVPMFIGA
                     MVMGPLGGWTIKKFDEKFQEKIRPGFEMLVNNFSAGLVGFALLLLAFYAIGPVVSTLT
                     GAVGNGVEAIVNARLLPMANIIIEPAKVLFLNNALNHGIFTPLGVEQVAQAGKSILFL
                     LEANPGPGLGILLAYAVFGKGSAKSSSWGAMVIHFFGGIHEIYFPYVMMKPTLFLAAM
                     AGGISGTFTFQLLDAGLKSPASPGSIIAIMATAPKGVWPHINVLLGVLVAAVVSFLVA
                     ALILHADKSTEDSLEAAQAATQAAKAQSKGQLVSTSVDTVVLTDSVEKIIFACDAGMG
                     SSAMGASILRDKVKKAGLEIPVSNQAISNLLDTPKTLIVTQEELTPRAKDKSPSAIHV
                     SVDNFLASPRYDEIVASLTGASPIAEIEGDIPTSAPVDSQEIDLNHIDAVVVAYGKAQ
                     GTATMGCETIRAIFRNKNIRIPVSTAKISELGEFNSKNIMIVTTISLQAEVQQAAPNS
                     QFLIVDSLVTTPEYDKMAARMYK"
BASE COUNT        10125 a         7632 c         6393 g         9820 t
ORIGIN      
        1 ataggggatt tacccactac aaatattata gagccaacaa taaaaagaaa aagtgtttga
       61 tagatatcaa acactttttt ctttgcctcc cactatctaa aaaaatgata atagatataa
      121 ttgtaaacaa aaatccagat aggttttgca tgattgagaa agttaaaaaa actatggcag
      181 agaatcgtta atctcagatt gtcggtaaaa cgataaacaa gggcaaaaaa gaaaccaatc
      241 agactataat ataataaact aattggatct ctgtgagata gtatcaaatg gctaatccca
      301 aagatgatag cagataggat aacatccaaa taatacttgg actagggaaa gaaggtattc
      361 ataaaatacc ctctatcaag agtctcctca aaaacaggac cgatgattac aggcaggaca
      421 aaagataaga tagtcgataa aaaggttggt tgtccatttg aaagaaccac ggtaaaatac
      481 tcatcatgaa tattcctatg attaatcaaa tgagcatagc gtgcccaaaa attaccgaga
      541 atctgataaa ccacataagt tgcaaataag gagaagacaa atgaccagtt ccagctcttt
      601 ttttcaaaga taaagagcat ctttttcttt tttaacctcc aaattaatag aaggaaactt
      661 cccactaata ccattgttaa aataagagaa tagacatcag ctcctaaccc taaaatgatc
      721 gtcacataca atccaattgt ttgtggtaaa taggtagata gtaaaataat aagcaaaaat
      781 attccaaatt gtcttagttt ctttgtgttt ctcatcgtac ttttttgaaa gattaccctg
      841 ctcggaagcc gtacttccaa gcatctatat aagaattaag tgccccttgc ctcatatagg
      901 gagcaaattc tctataatat aaccatctac tatatccatc ttcccaaaca gcaagaccac
      961 ctgaagtttg ctccaagtcc tcagttgaaa gaactgtaaa tgtatttgta cctgtcattg
     1021 caagtacctt cttaaaacat agtgatttga aataagatgt gaacaactct atcaggaaag
     1081 tcaaattaat ttatagaaat attttagcag ccaaggtgta ctgttataga ttcaatacac
     1141 tataaatttt tgtaagctta catctacagt atacatcttt tttgtctatt ttatagccca
     1201 tctcctcaac tgtcaatttt tcaacctgaa ttgcattttt ccataaaaaa tgagaccttt
     1261 ctagtctcat ttagtcattc ttagtatttt ctaaatcgtt gatagcgttc ttccagcaac
     1321 tcttctagcg gtttttgtga aagtctagcc agctccgttt ggagttcttt tttgacactc
     1381 ttaatcagtt ctttactaga aagtcctatt tcagaaatca ccttatccac cacgtccatt
     1441 tctaacagtt catgcgaagt gattttcatc agttctgctg cttccatagc gcgagtaccg
     1501 tccttccata aaatggaagc aaagccttct ggactgagaa tggcatagat agaattttcc
     1561 agcatccaga cacggtccgc gacagctaga gccagagccc cgcctgaacc accttcaccg
     1621 ataataatgg cgataatagg aactttcagg tcactcattt ccatgagatt gcgagcgata
     1681 gcttcccctt gaccacgttc ttccgctccg acaccaggat aagcacctgc tgtattgata
     1741 aaggtcacaa ctggacggcc aaatttctca gcctgtttca tcaaccgcag tgcctttcgg
     1801 tagccttctg gatgtggttg gccaaaattc cgtttgagtt tgtcttgcaa actcttgcct
     1861 ttttggatac caaccactgt tacagcttga tctccaagcc aaccaatacc accaacaact
     1921 gcaccatcat cacgaaaaga acggtcacca tgtaattgga taaattcatc aaaaatgcct
     1981 gtcgcaaagt ccaaggttgt caagcgactc tgctcacgcg cttctctgac tatttttgca
     2041 atattcatct aggactccct ccatgcaatc tgactaggct agcaatcgta tctggtaagt
     2101 ctcttctttt gacaatagca tccacaaagc catgttctaa taggaattct gccttttgga
     2161 aatcctcagg caagctttca cgaaccgtat tttcaatcac acgacgccca gcaaaaccaa
     2221 ccaagctctg tggttcagcc agaatgatat cgccttccat agcgaaagaa gctgtcacac
     2281 caccagtcgt tggatctgtc aaaatggtca ggtaaaagag accaacattt gaatggcgtt
     2341 taaccgccgc agagatctta gccatctgca tgagactcat gattccttcc tgcatacggg
     2401 ctccaccaga ggctgtgaat aggacaactg gcaatttttc gacagtcgca tactcaaaca
     2461 aacgagtgat tttttcacct acaaccgtac ccatagaagc catgataaag ttagaatcca
     2521 taatcccaag agccacagtc tgacctttaa taagagcagt tcctgtcaca acggcttcat
     2581 gcagacctgt tttttcacgc atagatgcca gtttcttttg gtaaccaggg aaatgcaagg
     2641 gatccttgct ttcaatccct gtaaacaatt ctttgaaggt tcccatatca atcgtcaaag
     2701 ccaagcgttc ttgggcagaa atacgaaagg tatagctaca gtgcggacag atacgttcac
     2761 ttcccagatc cttctgatag atggtatgct tacagcctgg acactgggaa aataattcat
     2821 ctggaacctc tggcttagct tgaggttttt ccctaaccga acgattggga ttgattcgaa
     2881 tatacttatc ttttttacta aatagagcca ttgattcccc ttttcggttt aaactcttaa
     2941 agtcatttta ttctttttct tgatatttag gtaagaaggt ttccatcaag aaggaagtat
     3001 cataatcccc agcaatgaca ttgcgatctg aaatgaggtc aagctggaaa tttgcattgg
     3061 tctgcactcc ttcaatctct aattcataga gggcacgttg cattttcatc aaggcgtcaa
     3121 aacgattttc gccgtgtact atgattttgg caatcatact atcataataa ggcggaatgg
     3181 tataacctgg ataaactgct gaatccacgc gcaagccaac tccaccactt ggcagataga
     3241 gattagtaat cttacctgga cttggagcaa agttaaaggc tgggttttct gcattgatac
     3301 gacactcgat ggcatgaccg cgtaggacaa tatcttcttg cttaacagac aaaggctgac
     3361 ctgccgcaat gcaaatctgt tccttaacga tatcaacacc tgaaacaaac tctgttactg
     3421 gatgttctac ctgaacacga gtattcatct ccatgaaata gaaattgcta cttgcttcat
     3481 caagaagaaa ttcaatggtt cctgcattct catagccaac aaactctgcc gctcgaacag
     3541 cagcagcacc tatttcatga cgcagcgttt ttccgattgc aatcgaggga ctttcttcca
     3601 aaaccttttg gttattcctt tgaagagaac aatcccgctc acccaagtga atcacatgtc
     3661 catgctcatc acctaggatt tgaacctcaa tgtgccgagc tggatagata acccgttcta
     3721 tgtacatggc accattgcca taattggcct tggcctcact agaggcagtt tcaaaggcag
     3781 aaacgaggtc atctggtttt tcaaccttac gaatcccttt accacctcca cctgctgaag
     3841 ccttgagcat aacaggatag ccaatttttt cagcaacaat caaagcttct tcagagttat
     3901 gcacttctcc atctgaacct ggtataacag gcacacctgc tttaatcatc tgagcacgcg
     3961 cattgatctt atcccccatc atatccataa catgaccaga tggaccgata aacttgatac
     4021 ctacttcttc acacatggtc gcaaatttgg aattttcact gagaaatcca aaaccagggt
     4081 gaatagcttc tgcctcagtc aagactgcag ctgatagaac tgcattaata ttgagataag
     4141 actctgttgc cttgccagga ccaatacaaa ctgcttcatc tgccaaaagc gtatgaagag
     4201 cttccttatc agcagttgaa taaaccgcta ccgtcgcaat ccccaattca cgtgccgcac
     4261 ggataatacg aaccgcaatt tcaccacgat tggcaattaa aatttttcga aacatggaga
     4321 acctccttag ttcccaattg caaaagtaag gataccactg gctgcaagct tgccatccac
     4381 ttcagccttt gcttcaacca cagctatggt gccacgacgt tttacaaaag tcgctgtcat
     4441 aaccaattgg tcgcctggta caacttgctt cttgaactta accttgtcca taccagcgta
     4501 aaagaccagt tttcctttat tttcaggttt tgataactct aacacaccag cagtttgcgc
     4561 caaggcttcc ataatcagaa cacctggcat aactgggtat tgaggaaagt ggccgttaaa
     4621 gaaaggttcg ttaatggtca catttttgat agcaacaatg gtatcctcgc tcacttccaa
     4681 gacacggtcc actagaagca taggataacg gtggggaaga gcttctttga ttccttgaat
     4741 atcgatcatt tgatacgtac caatccttta ccaaactcaa ccatttcttc gttagagacg
     4801 agaatttccg ttaccacacc atccttagga gctgggattt cattcatgac tttcatggct
     4861 tcgataatta ccaatgtttg accttttttg acactatcac caactgtaac gaaggcaggt
     4921 ttatctggtc cagcagccaa gtaaaccact ccaacaagtg gactctctac aagatttccc
     4981 tcagtagcca cacttgcctc agctggagct ggaacttctt ctgctacagt ctctgctgga
     5041 gcagatgtag gagctactgg actcggtgtt gctagaacgg gtgctggagc gacttgagtt
     5101 gcaacttcag gcacaggtct cgcttcattc ttgctaaact gcaactcatc cgtcccattt
     5161 ttataagaaa attctctcaa acttgactgg tcaaattgag tcatcaagtc tttaatatcg
     5221 tttaaattca tacttatcta ttctcccaac gtttgaaagc aagaactgca ttgtggcctc
     5281 caaaaccaaa agtatttgaa atagcgtatg gaatttcttt ctccaagcct tgtccataaa
     5341 cgacattagc ttcgatataa tctgatactt cacttgtccc agctgtcatt ggtacaaagt
     5401 tatggcgcat agcttcgatg gtgacgatag cttctactgc acccgcagcc cccagcaaat
     5461 gtcctgtaaa agacttggtt gatgatacag gtacttcctt accaagaaca gctacgatag
     5521 ctccactttc tcctttttca ttggcaggag ttgacgttcc gtgagcattg acataggcta
     5581 cttgctctgg agaaatctca gcttcttcca aggctagttt gatggccttg atagctccct
     5641 gaccttctgg atgtggagaa gtcatgtggt aggcatcaca agtatttccg taaccaacca
     5701 cttcagccag gatagtagct ccacgttttt cagcgtgttc aagactttct aaaaccaaca
     5761 tccctgaacc ttcacccata acaaacccat tgcgatcctt atcaaatggg atcgaagcac
     5821 gagttggatc ctctgtagta gagagagctg ttaaggcttg gaaaccagcg atggcaaaag
     5881 gtgtgataga agcttctgtt cctcccacca acatcacatc ttggaaacca aacttaatgg
     5941 agcggaaggc atccccaatc gcatcatttg atgaagagca ggcagtattg atagatttac
     6001 aaacaccgtt tgcaccaaaa cgcatggcta cattcccaga agccatattt ggtaaagctt
     6061 ttggaagagt cattggtttg acacgtttgg gtcctttttc atgaaggcga agtacctgat
     6121 cttcaatttc cttgattcca ccaataccag atgcaacgat aacaccaaaa cgatccctat
     6181 taagagcctc tacatcaaga ttggcatgat ttacagcctc ttgggctgca tacaaggcat
     6241 ataaagaata gttatcaaaa cggttggtat ctttttttac aaagtattta tcgaacggaa
     6301 aatcttggat ttctgccgca ttatgcacat caaagtcact atgatcaaat tttgtaatgc
     6361 caccaatgcc gattttccca gttgctaaac tattccaaaa ttcttctggt gtatttccga
     6421 ttggagatgt tactccataa cctgttacca ctactcgatt tagtttcatt cttttcacct
     6481 ctagctttcg ctacatactt aagccaccat caatggcaac cacttgacca gttagataat
     6541 cttggcctgc taaaaatact gtcaaatctg caacctgctc tgcctgccca aattctttca
     6601 tcggaatctg agctagtgta gcttccttaa tcttatctga taagatagct gtcatatcag
     6661 actcaatcat tcctggagca atcacattga ctcgtatatt ccgactagcg acctcacgtg
     6721 ccacagactt ggtaaagcca atcaagccag ccttagaagc agcatagtta gcttgaccaa
     6781 tattccccat caaaccaaca acactagaca tattaatgat agcaccttct ctggctttca
     6841 tcatcggttt caagactgat tgtgtcatat taaaggcacc agtcagattg accttgagca
     6901 ctttttcaaa atctgcttct gtcatcttaa gcataagagt atcttgggtg atccctgcat
     6961 tgttgaccaa aacatctact gaacccagtt ctacaatagc ttgatcaatc atacgcttag
     7021 cgtctgcaaa atctgataca tctcctgaaa tgggaaccac cttgatacca tagtttgaaa
     7081 actcagcgag caattcttct gagattgccc cacgactgtt taagacaatg ttggctcctg
     7141 cttgagcaaa cttgtgggcg atggcaagac caattccacg actcgaacct gtaataaaga
     7201 tatttttatg ttctagtttc atttttttcc tttcaaaact tctacttatt ttagtctatt
     7261 tttctaaaag tgctactaaa ctcgcttgat cttccacatg agctaagtga gcagttcgat
     7321 caattttttt aacaaaacct gacaaaactt tccccggtcc aatctcgata aagttgctta
     7381 tgcctgcttc ttgcatgacc ccaatacttt catagaaacg aacgggttcc ttgacctgac
     7441 gcgtcaagag ctgagcaatg tcctcttttt gcatcacagc agcttctgta ttgccgacta
     7501 ggggacaagt aaaatctgaa aaacttacct gagctagagt ttcagctagt ttctggctag
     7561 caggttcaag gagagcggtg tgaaagggac ctgacacctt aagaggaatc aagcgtttgg
     7621 cacctgcttc ttgcaaaagt tcaaccgctc gatcaactgc aaccacttct ccagcaatga
     7681 cgatttgtgc aggtgtgtta tagttggctg gagtaaccac tccaagttca gaagcttttt
     7741 gacaggcttc ttcaatgacc tctactggcg tattgagaac tgctaccatc ttgccagagt
     7801 cagcaggagc cgcttcttcc atataggctc cacgcttagc taccaaggca accgcatctt
     7861 caaaatccaa ggcgccgctt gccaccaagg cagagtattc tccaagagac aaaccagcaa
     7921 ccatatcagg ctgatagccc ttttcttgca ataaacggta gatagcaacc gaagtcgcta
     7981 gaatggctgg ttgcgtatag cgggtctgat tgagtttgtc ctcttccgta tcgatgagat
     8041 aacgcaaatc ataacctagc acctgactcg ctcgatcaat cgtttcttta acaatcggat
     8101 actgatcata gaaatcccgt cccatcccta gatactgggc accttgacca gcaaataaaa
     8161 aggctgtttt agtcatttct tacaactcct gcccagcgag aggcttcttc ttgaattttc
     8221 ttagcggctc cgtaatacaa atcttttagg atttcttcag ctgtttcttc tttagaaaca
     8281 agccctgcga tttgacctgc catgacagag ccaccctcca catcaccgtg aacaactgct
     8341 ttggctaggg cacctgctcc catttgttca aagatttcta aatcaggatc ttcctgctta
     8401 aaggcatctt tttcagccag ttcaaaatct ctagtcaact gatttttaat agcacgaaca
     8461 gcatgaccaa agtgctgagc tgaaatcgta gtgtcaatat cccttgcttt taaaattttc
     8521 tccttgtagt ttggatgggc attcgactct tttgcaacta caaaccgtgt ccccacctgt
     8581 acagcctctg cacctagcat aaagccagcc gcagcacctt caccatccgc aattcctcct
     8641 gcagcaataa caggaataga tacagctgtg gctacctgtc gcaccaaggt catggttgtt
     8701 aatttaccga tatgcccccc agcttccatt ccttctgcaa taacagcgtc tgcaccgatt
     8761 ttttccatgc gtttagctaa agcgacacta ggaacgacag gaataacgat tatcccagct
     8821 tcatggaaac gttccatata cttgcttgga tttcctgctc ctgttgtgac aactttaaca
     8881 ccttcttcaa taacgagatc cacgatatct tccacaaagg gagataagag catgatgttg
     8941 accccaaagg gtttatcagt caatgatttg attttatcaa tattggcctt gacaacttct
     9001 ttcggggcat ttcccccacc gataattcct aatcctccag ccttggaaac agcccctgcc
     9061 aaatcaccat cagcaaccca ggccatccct ccttggaaaa taggatagtc aatcttcaat
     9121 aattctgtaa tacgcgtttt catagtgcct ccaaccttcc ttgcttacgt aatagttcga
     9181 tttaaccata atttgacagt caaactatta cctaaacaag agggagtggg tttctcccta
     9241 ctccttctac taatattctg cttattttgc ttgctcttca acgtaagcaa ccaagtcacc
     9301 aactgttttc aagtcatttt ctgcttcgat ttggatatca aaagcatctt cgatttctga
     9361 gattacttgg aacaagtcca atgaatctgc gtccaaatca tcaaaagttg attcaagtgt
     9421 tacttctgat gcgtcttttc caagttcttc aacgataatt tcttgtactt tttcaaatac
     9481 tgccatgata ggactccttt aaaataaata gtttttttat aacaatgtgt tcaccacatg
     9541 attacctaaa ttgtaagaat gagcgtgccc caggtcaagc ctccaccgaa gcctgataga
     9601 agaacagtct ggctaccatc taaagggatg agaccttgtt ctacacactc tgaaagtaaa
     9661 atcgggatac tggctgcact ggtattgcca tattccatca tattggctgg aagtttggct
     9721 cggtcaacac caatttttct agccatctta tccaaaatac ggtcattggc ttgatgaagt
     9781 agcagataat ccaagtctgt cacctctata ggagattcat caatagtctg cttgatagac
     9841 ttggctacat ctcgaatggc aaaatcaaag actgtgcgtc catccatctt caaaaatgaa
     9901 tctgcacttt cttgatctga aaatggagaa tgcaaacctg aatgcccata agttaaacac
     9961 tcgctgcgac ttccatcgct attgagactc tcagctaaga aatgctcttg ctcgctagct
    10021 tctaacaaga caccaccagc accatctcca aacaacacag ctgttgatcg atccgaccaa
    10081 tcgactgcct tagagagggt ttcactacca atcaccaagc ctttttgaaa gcgaccagaa
    10141 gcgataaact tttcagcagt tgaaagagca aatacaaatc cactgcaagc cgcggttaag
    10201 tcaaaagcaa aggctttatt agcgccaata ttagcttgaa cacgagcagc tgtagagggc
    10261 atcatcgaat ctggagtaat ggtagctagg atgataaaat ccagttcttc tcctgttatt
    10321 ccagcttttg ccatcagttt cttagcaacc tctgtagcca aatcactggt agattctgtt
    10381 cttgaaatat gcctttgtcg tattcccgtt cgacttgaaa tccactcatc attggtatcc
    10441 ataatctgag ccaagtcgtg atttgtaacc acttgctctg gcacataatg agcaacctga
    10501 cttatttttg caaaagccat tatttcaaat cctccaaaaa ttggtaaaga ttagtcaagc
    10561 ctttacccat gacagcaatt tcttcctcgc tcatgccatc aataattttt tctaccatgg
    10621 ccttgtggaa gcgtttatgc agtctatgaa tcaagcgacc cttctttgtc aaatgcagat
    10681 gcaccacacg acgatcctgt tctgaccgaa ctcgctcaat gtagccctta cgctctaaat
    10741 tgttcaaact tgtcgtaaca gttccaagag ttaccatcaa ctcttttgac acttgacttg
    10801 gagtcacatc tggagcctta ccgatgacat caatcgtatg catttctttg atggagatat
    10861 ccttaaaacg actacctctc aagttcactt cctcaattac aaggacattg ttaaatatag
    10921 atgttaaata ttcattgatt cgttggtagt ccatttttca tatccctcct tcttcaaaaa
    10981 acttttacaa tcaaaacatt tgacagaaag aattatatca aaattcaaag aatgatgcaa
    11041 gtatttttta ttttcctgta aatttaggtc ttcttctctc cgaatgagct cgcactcctt
    11101 ctttgaaatc ctctgtttga gctaaggatt tctgtaggtt cagttctaaa gtagcgtaac
    11161 cctgccagtc tttaaattgg ctctcccaaa ccaacttctt aatggcagca taggaattac
    11221 ttgaagcacg tcttaatttt ttaagaagct gttctctcgt cttttcaagt ttttcagctt
    11281 cagaaacgcg gtaaaccaac ccccattcta gggctttttc tgccgttaaa gcctctcctg
    11341 tcatagctaa ttgagcagca cgcgtcacac cgatactgcg gctcaagaga tgaattcccc
    11401 ctgcatctgg agccaaacca acaccaacaa aggcttggat aaacttagcc ttatccgtcg
    11461 ccaaacagaa atctgccgca acagccatat tcgctgcggc acctgcaaca gcaccgtcaa
    11521 cttccattaa aacaggtttg gctatttgct tgattttata agaaatcgta ttgaccaact
    11581 ctgcgatttt tgtcaatgat ggaatatcat cctcatccac tgcccgcttc atctctacca
    11641 aatctccccc aactgagaag acctttccat tggcattgat taagataaaa tgcacagctg
    11701 gattttcttc tgccaaagtc agagcttcta aaatctcctc acacatggga atatgaaaac
    11761 catttgcgac ctcaggacgg ttcaaggtaa ggattgccaa gtcctcttca agttgataaa
    11821 taatgtgttc catcagggct cctttttatt ttataagcag tttatactct tcgaaaatct
    11881 ctttaaaccg cgtcagcttc catctgcaac ctcaaaacag tattttgagc tgacttcgtc
    11941 tagcttctta gtttgctctt tgattttcat tgagtgttaa attatttcac tgtcaaagta
    12001 tatctttttt aggagcagaa agcaagaaaa aatcgactga aagtgtctca gccgataaga
    12061 aaggctcgct ttaggctaga aagcatctta ttttcttcat tgaaaaaagc ctttctttct
    12121 gctataatcg tataaaatac ttactttagg agttcttatg aaagttgtta aatttggagg
    12181 tagttctctt gcctctgcta gtcaattaga aaaagtttta aacatcgtca aaagcgattc
    12241 agagcgtcgt tttgtagtcg tttctgcgcc tggtaaacgc aatgctgaag atactaaggt
    12301 tacggatgcc ctgattaaat actaccgcga ctatgttgcg ggtaacgata ttagcaagag
    12361 ccaaagctgg attatcgacc gctatgctgc tatggttagt gaattgggac taaaaccagc
    12421 tgtgctagaa aaaatttcta aaagcattca cgccttggcc actcttccta ttgaagaaaa
    12481 tgaatttctc tacgatactt tcctagcagc cggtgaaaat aacaatgcca aattgattgc
    12541 tgcctacttt aaccaaaatg gtatcgatgc acgctatatg caccctagag aagctgggat
    12601 tgtggtcaca agtgaacctg gtcacgctcg catcattcca tcaagttatg acaagattga
    12661 agaattgaca aacaccaatg aagtccttgt cattcctggt ttctttggtg tcactaagga
    12721 aaatcaaatc tgtactttct cacgtggagg ttctgatgtt acaggttcta tcattgctgc
    12781 tggtgtcaaa gccgacctct atgaaaactt tacggacgtt gatggtatct ttgcagccca
    12841 ccctggtatt atccaccaac cacactcgat tcctgagttg acctaccgtg aaatgcgcga
    12901 gttggcctat gcaggcttct cagtccttca tgacgaggct cttcttcctg cctaccgtgg
    12961 aaaaattcct ctggttatca agaataccaa caaccctgac catccaggta ctcgtatcgt
    13021 tctaaaacac agtaatgatg aatttccagt tgtgggaatt gctggtgact caggctttgt
    13081 cagcattaac atgtcgaaat acctcatgaa ccgtgaggtt ggatttggcc gcaaggttct
    13141 gcaaatcctg gaagaactta acatcggttg ggaacatatg ccaacaggta tcgacgatct
    13201 ttctatcatt ctccgttctc gccaactaac tcccatcaag gaagaagaaa tcctgcgtca
    13261 gttggttcaa aaggctaaag tagatcatgc agaaatcgaa cacgaccttt ctatcattat
    13321 gattgttggt gaaaaaatga agagccacat cggagtgact gctactgcga cacgcgctct
    13381 atctgaaaac aaaatcaaca tccagatgat gtctcaaggt tctagtgaag tttctattat
    13441 gtttgttgtc aataaagacc aagagaaagc agcaattaaa gccctctaca atgccttttt
    13501 tggagaaagt aaggaagact aagcatggcc caatcactta acaaaacagt actcctcagt
    13561 acgacaggca cttcctacct ctctatcgct gggaaagttg ggaaattcct tgtcggagat
    13621 caggctttgg aattttaccc agatgtcaat gtcgaacaat ttatccagat tccttggagc
    13681 catatcaatc agattggagc caatgtcact ggacgcaaaa tcagccgcca cttcgaagtc
    13741 tttacagaca aaggaaaatt cctctttgct tcaaaagact caggtgccat tctcaaaatt
    13801 gcacgcgaaa aactaggcaa tgacaaggtc gtcaaacttc cgaccctgat tcagacaatt
    13861 agccaaaaat ttaaaaatct atttgcaaaa aagtagaaac tttagtataa tcatagcaac
    13921 ggataagtag gttatcttct tctttcagaa agtctgcggg tactgcgagc agataggagg
    13981 gataggtgaa attctaccgt tagtaacaat tacatacaca atcaagtgca cacctgtgaa
    14041 gttggatgga accgtggccc tgccactcca acgttttgtc aggcgtgctt ttttcataaa
    14101 ggagttctta tgttagatat caaacgtatt cgtacagatt ttgaagctgt cgcagaaaaa
    14161 ttagctacac gtggtgtaga tgctgctgtc ttgaatgaaa tgaaagaaat cgatgctaaa
    14221 cgtcgtaaca tcttgatcaa ggttgaaact ctcaaagcag aacgtaacac agtttctgct
    14281 gagattgccc aagctaagcg caacaaggaa aatacagatg acaagattgc tgccatgcaa
    14341 aatctatctg ctgagattaa agccttggat gctgaattgg cagaaatcga tgctaaattg
    14401 acagaattta caacgactct tccaaatatc ccagctgaca gcgttcctgt tggggctgac
    14461 gaagacgaca atgtggaagt tcgccgttgg ggtactccac gcgagtttga cttcgaacct
    14521 aaagctcact gggatctcgg tgaagacctt ggtatccttg actgggaacg cggtggtaag
    14581 gtaacaggcg ctcgcttcct cttctataaa ggcctcggtg ctcgtttgga acgtgctatc
    14641 tacaacttta tgttggatga acatggaaaa gagggctata ctgaagtcat cacaccttac
    14701 atagtcaacc atgattctat gtttggtact ggtcagtatc caaaatttaa ggaagatact
    14761 tttgaactca gcgataccaa ctttgtcttg attccaactg ctgaagttcc tctgacaaac
    14821 tactaccgtg atgaaatctt agacggcaaa gatcttccaa tctacttcac tgctatgagt
    14881 ccgtcattcc gttctgaggc tggttctgca ggtcgtgata cgcgtggctt gatccgtttg
    14941 caccaattcc acaaggttga aatggtcaaa tttgccaaac cagaagaatc ttacgaagaa
    15001 ttggaaaaaa tgacagccaa cgctgaaaac attcttcaaa aactcaacct tccataccgt
    15061 gtcgttgctc tctctactgg agatatgggc ttctcagcta cgaagactta cgacttggaa
    15121 gtgtggattc cagcacaaaa caattaccgt gaaatctcaa gctgttcaaa cacagaagat
    15181 ttccaagccc gtcgtgccca aatccgttac cgtgatgaag cagatggcaa ggtgaaactc
    15241 cttcatacct tgaacggttc tggacttgca gttggacgta cagtggctgc aattcttgaa
    15301 aattaccaaa atgaagatgg ttctgtgacc atcccagaag cacttcgtcc atacatgggt
    15361 ggagctgaag tcatcaaacc ataaaaaata aggtttagct atttctagct agaccttttt
    15421 tcgtaaccaa atcagataag cacctagtac aaagaataaa atagttaggc atataatggt
    15481 ttcagccaat accaggtaat ccagaaatgg aagtttcaaa attccctgag ccatcttgag
    15541 cgaggtcgct gtgataatgg ttgggaaggt gagggctgag aaggctggtt gaaaaccttg
    15601 ttttaaaatg ttgggcagac gagttaaaac aaagaaaaag aaggattgag aagccaaaat
    15661 catgacaatc aagccccaag tcggcaggct ggttcctcct actcgaacta gagaagccaa
    15721 gagtagagag aaaggagcac agtagattcc ttcttgtcca agcaaggcta gtgggagtgg
    15781 atgtttcttt aaatcgctat aaataagggg atagagatag aaggtcaaga gaaaaccaaa
    15841 actcaaggtc gcataggcaa tttcgataat acctaccaga ggataggtca aggcagccac
    15901 tgctatcccc acatagagaa ccgtccaact tggagtggca tgaaccctcc gccctggaca
    15961 agcaaacttg atggtaaaac cagcaatcaa ggtcaaatcc aagagaaatg aaaaccacca
    16021 aatcccttgt gctaccaaag gaagataaga gaatacgcga aagacatagg tcgataaaat
    16081 catcccagcc ataggaaagg ttgccattcc tgacaaaaga gggggcttgg tcaattcttg
    16141 cttggtttct ttccaattaa agagatgcag aattagaaag taaatccata aaaccaaacc
    16201 agtcagacta aaaagatggg atagaaccgg caacgtatct aaaataagat ttccagctcc
    16261 tgccaaacct agcaaacaac ctgaaaatac taaggggagt tttttcatcc taacctccaa
    16321 taatcatgtt agtttcagta taacataaaa gcgcttaaat gaggatttaa aaaaacgaag
    16381 tccgcttatt tcagacttca ttttactcag atatgaatta ggcataaggt tgcaattctg
    16441 gattaattgg tgtattagct aagttgttgg catagttaca gaggattgct aggctgacac
    16501 caaaaaccac atccaaggca ttttgttgag tgtagccagc ttctaaaaac tcagacaagg
    16561 cttcatctcc tacacgaccc ttggtattga taactgccaa ggtaaactta gctagggtat
    16621 ccaatttagg atctgtttca attggagtac gattgcgaag agcttgaatc aagtcatcat
    16681 tcatctggat ttgtttgatg gaaaaggctg tgtgacctgc gacacagaag gcacaaccat
    16741 tggtcacggc tgccgtgatt tgcaccactt cacgctcaac gggtgtcagg ctgttgcgac
    16801 ggtggataga tgagacaatt tggtaggctt ctaaaacagt cggggcattg gccaagagac
    16861 cgattaggtt gggaatatag ccattgttgt ctttttctac tgtttcaaga atttctttca
    16921 cttctgctgg tgctgactct actgtatgga tagtaaatgt tgtcataaga tacctctttt
    16981 cttattattg acactaatat tattggaaaa tcttataaaa tcctgattcc taagtttatc
    17041 taagataaag ctttattctc tcataagatt ttcgttgtta tattagttta tcacacttcc
    17101 aatcacttgc ataatatata ttatatatca ggctgataaa aattatttat aggcaaaaaa
    17161 atcacacgag ctgtgtgatt ccattatttg tcaaaatact ttttagtttc agcaataacg
    17221 actggcgaca agaccaagag ggcaatcaag tttggcagag ccatcaaggc gttaacgata
    17281 tctgcgataa tccagaccat atccaactcg ataaatcctc ctaacaagac catgagcaca
    17341 aaaaccacac ggtagagcca gataaagcga accccaaaga ggaactcaaa acagcgttct
    17401 ccgtaatagt tccaacctag aatcgttgta aaggcaaaaa gcacaaggaa gatggtcaag
    17461 agggcagggc caaagtgtga aaagactgtt gagaaagctg actgagtcaa ggcaacccca
    17521 ttcaagtcac cactccaaac tccagttacc aagatggtca aaccagttag agtacaaatg
    17581 atgagggtat caataaaggt tcctgtcatg gaaatcaaac cttgctctac tggttcattt
    17641 gtcttggcag ctgcagctgc aataggagca gaacccagac cagattcgtt tgagaacaca
    17701 ccacgcgcca caccattttg aatagccatc cgaacgctag caccagcaaa tccacctacc
    17761 gcagcaaggg gactaaaagc tgaggtaaag actaaagcga ttgtgccagg gatttttccg
    17821 atattaaaga aaataactgt aagagttcct aagatataaa tgatggccat aaaaggaaca
    17881 acagtagttg aaaccttaga aatagacttg agtccaccaa agactgcaat cgctacaaag
    17941 acagacaaga cgagagctgt gatggctggc gaaatcgtcg ttgtattttg gatagattct
    18001 gtaatcgagt tgacttgggt gaaggttccg attcccaaga gagcaaccaa tactcctgct
    18061 actgcaaaca aaacagcaag tggtcgccac ttttctccca tccctagaag gatataatgc
    18121 atgggacctc ccgctactgc accatggtcg tccttggtgc ggtatttgat ggccaagagt
    18181 ccttccgcat acttggtagc cattccaaag aaagccgcca tccacatcca aaatagagct
    18241 cctggtccac caaccttgat agccgtcgca actcctatga tatttcctgt tccaacagtt
    18301 gatgccaagg ctgtacacag agctgcaaaa ctggatacat caccatgtcc cttatcctgg
    18361 ataaaaataa gctgaaaggc cttgggcaga cgcaaaacct gcaagagtcc tagccgcatg
    18421 gttaggtaaa tccctgttcc gaccaataaa atcaagaggg gcggtcccca agcaaaatca
    18481 tcgattgatt taagcaattc taacatttcc ttctcctatc gtttcaaccc caaaagaaag
    18541 agcacatgca agatacatgt actctggaat gcttagataa atgctaaaaa gcggtctatc
    18601 ctagctctgt ccttttacct gagagtttga gcagttgcct gccttgcccc ttcggtgcct
    18661 ttacggtctc tccagagttc cgtccattta cagtcatgga aaatcaaacg attccccact
    18721 tctattaaac ttcattcggt gttggtattt aattgattct aattttacaa aaaatgttgg
    18781 cttttgtcaa tgtgtttatt agtaaaaatt agttcaacag tttttacttt ataaagtcca
    18841 gaatactgct atcctttaaa agtgacaata gtcgcaccac tgcctccagc attttgtggg
    18901 gcatagccga aactcttgac atgtttgttt ctttgcaagt atttggtaac tccttcacgg
    18961 atgactcctg ttccgatacc atggatgata tcaacttgag ccatattgtt aagcaaggct
    19021 tggtcgatga aggcatctag ctcattcatg gcttcttcat agcgcttgcc tcgaagatcc
    19081 agtctagctt gaggtcctcg cccagaagtt cgtttcacaa cattgacctg tttcttcttg
    19141 actggttttt cttgctgggc ttgaacaaga tcaaactctt tctcttccaa ggtcatctta
    19201 atcaagccaa cttgggcttc ccagcgaccg tccttgagtt gactggtcaa ggtaccacgc
    19261 tgaccataac tgagaaccac gatatcatct cccacctttg gagctcgttt tttcttggcc
    19321 ttttgaagga ccttattttt agacaagtcc actttttcag gagccaattt tttcaacttg
    19381 gccttggctt caatgatttc gtggggcttg agttgggatt tactgtggag atttttgaga
    19441 atctggtcac tttcacttag ggccatatcc acaatctcag cagcctgttc acgcgccttg
    19501 ttaagctcgg tttccttttc acgattaagc tcgttgtaga gtttttttag cgcacggttc
    19561 atcttgagat tttcttgctc cacctcacgg atattgtcca agcgtttgcg gctttccagc
    19621 gtctgctctt ctaattgctc aatgatacga ttgacgtcat tgtcctgatc gatctgctga
    19681 ctggcatctc ctacgataac ttcagatagg cctagacgtt tggcaatttc aaaggcatta
    19741 cttcggccag gaacaccctg cataaagcga taggtcgggc gaagagttgc agtatcaaac
    19801 tccatactgg cattttgcac aaaggctgtc tcaataccgt aggccttgag ttctggatag
    19861 tgggtcgtcg ccatggtctt gatttgacgc aggcgaaggt cctccagaat agccatggca
    19921 agggctgctc cctcttgggg atcagtacca gcccccaatt catccaaaag taagagtgaa
    19981 tgttggttga ccttgccaag aatatccacg atattggtca tatggctaga gaaggtagac
    20041 aagctctgct caatagactg ctcatctcca atatcagcaa aaatttcttc aaaaatacca
    20101 acacgacttc ccttgtctgc taaaatcggc aatcctgact gggccatgac ctgtgtcaag
    20161 cccagagttt tgagcatgat ggtcttccca cctgtattgg gacctgtaat gacaatagct
    20221 gttaaatctt gaccaaaata gacatcattt gcgacggcat ttttgaccaa aggatggcag
    20281 acatggagca gttgaatctc ttgattttct gacagctgag gcacgactgc ttgtctttct
    20341 tggataaatc gaaccttggc acgaatcaag tccagatgac cgataatcca agcatcatta
    20401 gcaatctcag ccgcatgagg gcggacacgc tcagaaattt cttggagaat gcgaagcatt
    20461 tcatagcgct catctgctcg cagactagca atttcttcgc tcagtttgac tacctcacgg
    20521 ggttcgatat agacggtgtt tccactagca gaaatatcat gaacgacacc tgcaatctta
    20581 ttgcggtagg tgtttttgac tggtaaaacc ttacggccat ttctgctagc aacaattcct
    20641 tccgtcaaca tctgcgcttt ttgcttgagc aagtcttgta aaacatcgcg tacctgactc
    20701 tcgctatcat gtatttttcg acggattcgc gccaattctt cactggcaaa attttcaatg
    20761 aaacccgcat cattaaaggc ctgaagattt ccttgtaatt gcggaaaatc atgtaatttc
    20821 tcaaaccaaa gggctaattc ttccaagctg acattttcca gattggcgta aaaactttga
    20881 agttctcggc tggcaagaag cacgcgtttc aagagtagga actcctcgat attgagatcc
    20941 gctcccatct ccaacctctt gcagactcct gcaatttcct tagttgagag aatagtaaaa
    21001 tgcggttgct cgacgaaaag agcctgcatt tccttcatct cagcaaaagc ctgtttgatt
    21061 ttatctgctt tggcagtcgg agccagttgt ctcaattgct ccaagccctg ctcggtcaac
    21121 aaatgaggct caaacaaggc cttgacctta tcgaactcta atgtttctaa tattttctta
    21181 ttcatcttta tttccttgtc tttgaatgtc taggtgtggt agctttttac attctgatag
    21241 attcaagtca aatctgtaaa caaagggcta ggaaaactcc tgcccttttt atccgattaa
    21301 atttgtcacc cagatttgtt tgagccaact ggttgttatc ggtatgctct ggatgatgtg
    21361 ttttgcgacg atactctttt caagaggatt ttgtataact gccatgggga tggtcgccaa
    21421 gattgtcaag gccatttgca agacaaataa ggtcaccaac atggacaaga tacctgctga
    21481 aacttggaac aacttaccac ccagtttttt gctaggaatc aagtgtaaga gaagaccaag
    21541 caaacgacca atgctataga caatcccaaa tacaagcaag tagccgatac ctgcataaaa
    21601 gaccttatcc agctgaaaga gttgatccga tgggaaaaag aaagtcccct gaccttcctg
    21661 cgaatttgca taagggagca ataaatggaa ttgctctcca agccccttat aaaactgacc
    21721 agccataaaa gccgatgcca tggctgaaat caggtaataa atctgtaaga gcaggcctct
    21781 ccgatagccg atataaaatc cccaaaccaa gaccaataga agaaggaatg aaatcataag
    21841 gaatcctcaa tcttgctctg ttcttgctta caagtcacaa gcttgtgacg gagttcttct
    21901 agctcttgct ccttatcgtc aaattcaatc tcacggctga gctgagttga taaacagttg
    21961 actgccaaca aaagagcgat tgtttcatca tctgcgctag gcatttgttc tttaattgct
    22021 tggtattttt ctgtcgcaac cttagcgatt tcctccataa aaaggttatc atgttcactt
    22081 gtcaaggtta acgatttttt cccgaatgta aatttgaatc gatttagatt tgccataaaa
    22141 ttcacctcac gatattatac caaaattcgc taattttgtc agtttttaca aattttactg
    22201 cttttgtggt acaatagaaa ctatggcaag tatcacactc acaccaagcg aaaaggatat
    22261 tcaggctttt cttgaacact atcaaaccag tctggctcct agcaagaatc cctatatccg
    22321 ctactttttg aaactacctc aagcaacggt ttctatctat acttctggaa aaatcttgct
    22381 tcagggtgaa ggggctgaaa aatacgccag tttctttggc tatcaagctg tagagcaaac
    22441 cagcggacaa aatcttcctt taattgggac agatgaggtg ggaaatggtt cctactttgg
    22501 tgggcttgca gttgtggctg cctttgtcac acctgaccag cacgactttt tacgaaaact
    22561 cggtgtggga gattctaaga ctctgaccga ccaaaagatt cgtcagattg ctcctattct
    22621 caaggaaaaa atccagcacc aggcactcct tctctcaccc agcaagtaca acgaggtcat
    22681 cggagaccgc tacaatgctg tttcggttaa ggttgccctc cataatcagg ctatctatct
    22741 cctccttcaa aaaggtgttc agcctgagaa aattgtgatt gatgccttta ccagtgctaa
    22801 aaattatgac aagtacttgg cacaagaggc caatcgtttc agcaatccta tcagcttaga
    22861 agaaaaggct gaaggcaaat acttgtctgt cgcagtttct tctgtcattg cgcgtgatct
    22921 ctttctggaa aatcttgaaa atctgggacg agaactgggt tatcagcttc caagtggagc
    22981 tggaacggct tctgacaagg tggctagcca gattttgcaa gcctatggta tgcagggact
    23041 caacttctgc gccaaattgc actttaaaaa cactgaaaaa gcgaaaaaac gcttggaaag
    23101 gtaagttatg aattcattta aaaatttctt aaaagagtgg ggactgttcc tcctaattct
    23161 gtcattacta gctttaagtc gtatcttttt ttggagcaat gttcgcgtag aaggacattc
    23221 catggatccg accctagcgg atggcgaaat tctcttcgtt gtaaaacacc ttcctattga
    23281 ccgttttgat atcgtggtgg cccatgagga agatggcaat aaggacatcg tcaagcgcgt
    23341 gattggaatg cctggcgaca ccattcgtta cgaaaatgat aaactctaca tcaatgacaa
    23401 agaaacggac gagccttatc tagcagacta tatcaaacgc ttcaaggatg acaaactcca
    23461 aagcacttac tcaggcaagg gctttgaagg aaataaagga actttcttta gaagtatcgc
    23521 tcaaaaagcc caagccttca cagttgatgt caactacaac accaacttta gctttactgt
    23581 tccagaagga gaataccttc tcctcggaga tgaccgcttg gtttcgagcg acagccgcca
    23641 cgtaggtacc ttcaaagcaa aagatatcac aggggaagct aaattccgct tctggccaat
    23701 cacccgtatc ggaacatttt aagaaaccta agaggccgag aatcaccaat ctcagcctct
    23761 tcttctatcg tgagaagtga ttgtttattg acaaatactc aatgaaaatc aaagaacaaa
    23821 ctaggaagct agccgtaggc tgcttaaaac agtgttttga ggttgcagat ggaagctgac
    23881 gtggtttgaa gatattttcg aagagtataa aataaaaaca atcccaactc tcacctattc
    23941 atgcaaagga attttatgga agtttatttt tcaggaacca ttgaacggat tatttttgaa
    24001 aatcccagca atttttatcg catcctcctc ctagaaatcg acgatacgga cgcagaggat
    24061 tttgatgact ttgaaatcat tgtcacagga accatggctg atgtaattga gggcgaagac
    24121 tatacttttt gggggcaaat tgtccagcac tccaagtatg gagaacaact gcaaatcagt
    24181 cgttatgatc gcgcaaaacc aactagtaag ggcttggtca agtacttttc aagtagccat
    24241 ttcaagggga ttggtctcaa gacagctcag aaaatcgtgg atacctatgg cgaaaatacc
    24301 attgacgaaa ttttgcaaca cccagaaaag ttagaaggca tcgcaggact ctctgccaaa
    24361 aatcgcgagg ctttcgtctc cactctccgt ctcaactacg gtacggagat ggttttggcc
    24421 aaactagcca actacggcat tcccaacaaa ctagcctttc agattcaaga cttttacaag
    24481 gaagaaaccc ttgatgtggt tgaaaattat ccctaccaac tggttgagga tatcaagggt
    24541 ttgggcttta ccattgctga ccaactagct gaggaactag gcatcgaaag tcaggctcct
    24601 gaacgcttcc gcgccggtct agttcacagt ctttttcagg cctgtatgga aacaggagac
    24661 acctatgttg aagcacggga tttgctggaa caaaccctta ctctccttga gtcttcccgt
    24721 cccgtggaac tagaccccag ccaagttgcc caagagctct cctacctgat cgaagaagac
    24781 aaggttcagc agattgatac caagatcttt gacaacagcc tctttttcgc tgaggaaggc
    24841 atccgcagtc acttggttcg tatccttgaa aaaggagaac agaagagtca tgatttagaa
    24901 accattcaaa aacatatcac tactatcgag gaagagctgg gaattgagta tgataacatt
    24961 caaaaacagg ctatctgtga tgctatccag aataaggtct ttatcctgac aggtggacct
    25021 ggtactggta agacaactgt tatcaatggg atcatcgctg tttacgccct gttagaggga
    25081 cttgacctca ggaagaaaag caatctgccc attcttcttg ctgctccaac tggacgagcc
    25141 gctcgccgca tgaatgaatt gacaggtttg cctagcgcga ccatacaccg ccacttggga
    25201 atgacaggtg acgatgatac cagtcatctg gaagattacc tagatgctga ctttatcatc
    25261 gtggatgaat gctctatggt agatacttgg ctggccaatc aactcttctc caatatctct
    25321 tctaacagta agatcctcat cgtaggtgac agtgatcagc taccttctgt cagtcctgga
    25381 caggttctag cggatctgct tcatattcct ttgattcctc agactcgctt ggaaaaaatt
    25441 tatcgacaaa gcaaagaatc aaccatcgtc accctagcta gtcagattcg acagggcatc
    25501 ttgccagctg atttcaccca aaaaaaagct gaccgttcct actttgaaat tgctagtggc
    25561 catattcctg ccaccattga aaaaatctta ggtgccgccc tcagaaatgg tattcctgcc
    25621 cgtgatatcc aagttctggc tcctatgtac cgagggacgg cagggattga tgctatcaat
    25681 cagctcatgc aagacctgct caatccccca caaaaagatc aactcagttt tgaagctcct
    25741 cagtgccact atcgtaagag agacaaggtc attcatttgg ttaacgatgc tgaaatcaat
    25801 gtctttaatg gggatttagg agctatcaca gacctgattc ctggtaaata caccgaatcg
    25861 aaacaagacg agattgtcat tgattttgat ggtaatgaag tctcttaccc ccgtaacgaa
    25921 tggtacaaga ttcgcttggc ctatgccatg agtattcata agtctcaggg aagtgagttc
    25981 ccagttgtca tcctaccgat tactagtgct agccgacgta tgctggagcg aaatctcatc
    26041 tacacagcca ttacacgtgc caaaagcaaa ctcatcttac taggcgaatt acaagccttc
    26101 gactatgcta cccaacacat cggaactgcc cgaaaaacct atctgattga acgcttcagt
    26161 gatctactgg agaatgttga agaaaagcaa caagctgtct ctgaaacagt cacatcaagt
    26221 gcctctgaac aatcctacat cctaaccgaa gaaaactggg acagcattcc agccatgatt
    26281 gggattacag acacagacct caaagagatt tttggaaaat agtacatcag aaaacccacc
    26341 aattcaggtg ggttttctgt ttattaagat tattttactg ttgctgtgct tgtgatcaat
    26401 tcaacagctt ttttgatagt gatatcatgt ttcaacatgt cagctgaaag caagttttga
    26461 acttgtgcaa cttccatgtt gtagtctgct gccaattgct caacttcttt ttggatttct
    26521 tcttctgaag catcaaatcc ttcagctttg gcaactgctt cgataacaag gttagtctta
    26581 gtacgtgact cagcttctgc ttggtattgg ttgtgaaggt cttcttgagt agttccagtg
    26641 atttggaagt acatgtcagg gttgatccct tgacgttgca agttcccaag gaattcattt
    26701 actgaacggt gaacttcttc atggatcatt tcttctggaa gttctacgat ttcagcgttt
    26761 tctacagctg tatcaattgc tgcaccttca actgcatctt tgtaagcttc ttctttagca
    26821 gcagccaatt ctttgcggta tttttctttc aagtcagcaa gtgtttcaac ttcttcatca
    26881 atgtcttttg caagttcatc gtcaagagct ggaacttctt tagcttttac ttcgtggata
    26941 gttgtcacga atttagcttc tttacctgca aggtcttctg cttggtagtc ttctgggaat
    27001 gttacgataa catcaacggt ttcgccagct gagtgaccta ccaattggtc ttcgaaacca
    27061 gggatgaatt gacctgaacc aagtccaagt gagaagtttt caccttttcc gccgtcaaat
    27121 tcaacaccgt cgatagaacc aacgaagtcg atcacaacag tgtcgccgtt ttcagcagca
    27181 gcttccttga taaccaattc agccaggttg ttgcgttcgc gttcgatacg ctcttcaaca
    27241 tcagcgtcag ttacttcttt ttctacatca actgatactt caaggttttt gtagtcaccc
    27301 aattttactt caggttttgt aacgacttca gcagcgataa cccagtcttg acctttttcc
    27361 attgaagtta cgtcaatttt tggttgggca accacttcaa gaccagcttc ttttacagct
    27421 gcttcataag cgtttggcaa aagagcgttc ataacgtctt ggtaaagtga ttcttcacca
    27481 aattttttgt cgaagatagg acgtggaagg tgacctttac ggaaacctgg aacattaaga
    27541 gatttcttca ctgacttgaa gacacggtcc aattctggtt tgatttggtc ttgagagata
    27601 gtgaaagtca agacaccacg gtttgtttct ttgttttcaa atgatacaga cattctgtca
    27661 tttctcctta aaatttttta aatacagtct attataacat tttctataaa taaaatctag
    27721 actaatgcag ccaattatag acaacaagcc tttttcctaa ctaaaacact cataaagtat
    27781 agacaatttt agactacttt ggatatcttt tggttagtca ttttccaaaa ctaatttatc
    27841 taatttttca gttatatagt agattgaaac tagaatagta cacctctact tctaaaacat
    27901 ttttagaaat cgatttgact gtcctgatcg atttgtcctg ttcttgtttc attttactat
    27961 atagatcgca ttcgaaagaa ttcgttccaa aattgcttgg ttcgtttttc tcttggacga
    28021 ctaaagaatt gatgggcatt atttttttca acaattttcc cacagtccat aaaaataaca
    28081 tgatgggcta catctctagc aaaacctatc tcataaagct aatcaaaaac tcaatctgag
    28141 gagaaaatcc aataaggctt tccataataa aggacatcct atcaagattt ttgaacaccc
    28201 gataggctgc ctttttccga ttttgaagac tttttgtcca gcttctttta ccttataaat
    28261 aacaacaaaa atcaaagaca agctagaaag attaccgcag ataactcaaa cagtgttttg
    28321 aggttgcaga taagactgac gaagtcagta acatatgcct aagacaaagc gatgctaacc
    28381 tgatttgaag agattttcga aaaatattaa atatactcta caatttgatc aatcaattct
    28441 tggtcgtcta aacctgtaac ttgtataaca acatctttga ctgattgttt agccaacaat
    28501 tcacctaatc gaatactttc ttcatcattt acatcgcgat agtcaaaggc atagccaact
    28561 gttttaagta ggtttttata tgacaaactg agttctttca attcacgtat cggccggatg
    28621 aatcgttcat tatagcctaa ttttcggatt ggagtacgag ctacgcgact aacctcgtcc
    28681 actatgaaag ggttttcaaa ccgttctata atgactttgt gataattctc caattctttt
    28741 ttatcaaagt tccatttggc aatcaagaga ctccgaattt cagctaatac agattcaatc
    28801 cgagatttga tattaggatt ttgaagagct tccaaaattg tcttggcacc ataatgcgca
    28861 ccaatgtaag ctgaagttgc atgtccagaa ttgactgaaa aaagttttcg ctcaataaag
    28921 ggttctaaat cttcttcata atgcacatct tttagacgta aatctggatt tttaagacgc
    28981 ttggtttcca cgacccattc attaaagggc tcgaccacaa caaaaaggga atcttcgtga
    29041 ctttgtgctg gaacaatcct gtctaccgca gcatttggaa aacctatgta gttatcagca
    29101 aatgtcaaac cttccggact taaatatttc ttgacttctt gataaagaaa ttgagacccg
    29161 ccaatcatat tttcacaggc cataacatcc aatacctgtg tattccctgc aactcggcga
    29221 gcttcgattc ctttggctag aagttcagcg ataaaaggga gtatattagg tccgattgca
    29281 gtagtaataa tatccgtctt ttgaatcgct tcaatgactt gctcaggatg ttctttgcta
    29341 ttaatgccag ccacattagt tacttctata cgagactgtc ctttctgtgc aatttcaatt
    29401 tcatacttgc ccttttcatt tagagcatga attatctgat tattgacatc cacaaaatca
    29461 atatggaaac catttttaaa tagaatttca cctataaaac cacgaccgat attaccggca
    29521 ccaaaatgaa cagaatgttt cattcaattt ctccttttcc tatttgaggg acatatatac
    29581 tagatgacaa atgacgaaat tcaattattc aacagcatca aataagcgca atacttcctc
    29641 ttttgactga gcatctgcta gtttaagaac attatccaca tctgcacaga agatagaaat
    29701 tttctgaata atttctaagt gttcattacc aataccagca ataccaaaaa gaaccgttgc
    29761 cacttgaggg ttagatacat tcccaaaatc aacccctcta gggacttgaa cgactgtaat
    29821 accagactta aggacatcat tttttgctgc atctgttcca tgtggtatgg cgataaagtt
    29881 acccatgtaa acagatagct ctttatctcg ctcaatcatg gcttcaatat agtcttcatt
    29941 aacatatcca ccctcataaa gaacttgccc acaataacaa atagcttcct ccttgttaga
    30001 aaattgttta ttaagcttaa tcaaatgttt ttcaagtttc atattagttc tccaatttct
    30061 taattttttc gttaaaaata gtatttagca tctgataaat aatggattga tttcccgtct
    30121 tgtaaatctc tgtataaaga tgattttcaa taatcgactg actaatagct gtcattaaat
    30181 ctctagcttc ctcgctagct tctttagaca ttagcattag cagacacctt ttgacctctt
    30241 cttcctctcg tttcattgac aatgcggaga taggtagttt gagttcaaac atagtaaaac
    30301 tatttgttgt tactttgcta gactgactat gtaaaagcac cagaccagta ttaggaatag
    30361 ccataggact attctggaag tgagataaca attttcttgt taggtaatct ctgtcactca
    30421 cattcttctg atattggatg atttgttcta ccgtgtgctc aaatgattga ttattctcca
    30481 attgaaccaa ctcgaattga ctcaaaagct gactactaga tattaaataa tcttgcaagt
    30541 cataactttt ctctggagcg atagcatcac gcgcgacaat tgtacgatgt gcctgtacat
    30601 actgaagtcg ttcctgtaat tcaaacaatt ctttgacggt tggaaaacta gaaattacat
    30661 cgatttcctg attagtcagc ggcttggtag ataaaatata atcatactga ctgagatcaa
    30721 tactgtggta atctactaga gactgaatat ctatcaactc tacaaaagga gcaacactct
    30781 taattttact gactaataaa tctctagtga cccgacgttc atccgttaaa agcaaaacac
    30841 ggactggata aatctctgga ctacggccta agctagagat aaaatgtagg gcaatcatgc
    30901 catactcata ctctgtatga agatatttcg gaaaaatatc attcactaaa agactgatga
    30961 ctgtataaag aaatttattc ctttcaacta aaatctggac agattctggc aaattttcac
    31021 cctgaaaaag gatagggacg cctaaactga gccgaatatg atggaaaaga aaattgaata
    31081 aaaccttgtc cttaaaaaag tcaatcttgg tatacatgga aaccgtatca atcagatttg
    31141 aaatattgta gaaaaattca ccatcaaatt tctccgtaaa gagcggattg tcctgacgtt
    31201 taatgattaa ttcatccaag atgctcgcaa aatagataat ttcctgaata ctataaaatt
    31261 gtgcagtctg cttagagtaa gcttgaaaaa ttttttgaga aatttccaaa gcctgcttac
    31321 tagtattagg tgaattttca atgttttgct cctgacctat aagagataac aagatcgcaa
    31381 aaaacatctt catcctagca tccatatctg gaaaacctga cagttgctta ttaacaatct
    31441 gactggccag cctagttcta tctgcttcta aaatatcaaa gctcccaaaa ttaccggttg
    31501 aaaaatctgc tactgagata cagtttgtca gtaaaatagc caaaaatctt ctcttaccaa
    31561 ctgaatcacc agaaatccga taaccttttt gtcgttcaat tttcagatca aagtctaaaa
    31621 gacgcttatc aatatctgaa atatcctgaa taatagttac attactgact ttcgtgcact
    31681 cttgcaatgc ttcattggtg acaaaaccac tctcagtcag aaggcgatag gtaatcaact
    31741 cttgtctttc ttggggacta tactcaacta acacttcaag ttctgtcggc aaatcatcca
    31801 actctccagt caaaatatag tatttcccat gcttcgttat ttcgattcca tattgctcca
    31861 tgctatctgt caaatctgat aaagttcgat aaattgttct agatgaaacc tgtaagattt
    31921 cagtcatatc ttgcattgaa agcttcccta catgtaggaa agccttcaat aattgttctt
    31981 ctcgtttggt taatagcatt cgtaatttag aaacctctag ttctatttgt acattctagc
    32041 agccattttg tcatattctg gtgttgttac taaactatcc acaataagaa attgagaatt
    32101 cggtgctgct tgctgcactt ctgcctgtaa agaaatagtt gttacaatca ttatgttttt
    32161 agaattaaat tcacctaatt ctgaaatttt ggcagtagaa actggaatac gaatattctt
    32221 gtttctaaaa atagcccgaa tcgtttcaca gcccatagtt gcagttccct gtgctttacc
    32281 ataagcaact actacagcat caatatggtt aaggtcaatt tcctgactat ctactggtgc
    32341 tgaagttggt atatctcctt caatttctgc tattggagaa gctcctgtta atgaagctac
    32401 aatttcatca taacgagggg acgctaagaa attatcgaca gaaacatgaa tagcacttgg
    32461 actcttgtct ttagctcttg gtgtcagttc ttcctgagta acaattaatg tttttggtgt
    32521 atcaagcaaa tttgagattg cctgattaga tactggaatc tctagacctg cttttttaac
    32581 cttatctcga agaatactag ctcccatagc agagcttccc ataccagcat cgcaggcgaa
    32641 aatgattttt tccactgagt ctgtcaaaac aactgtatca acagaagttg atactaactg
    32701 acctttagac tgagccttag ctgcttgggt agccgcctga gcagcttcga gcgaatcctc
    32761 agttgacttg tctgcatgaa gaataagggc tgctacaagg aaagaaacaa ctgctgctac
    32821 taaaacacct agaagaacat ttatatgggg ccaaacacct tttggcgccg tagccataat
    32881 cgcaataata gaacctggtg aagctggaga tttaagacca gcgtctaaga gttgaaaagt
    32941 aaaagttcca gagatacctc ccgccatagc agctaaaaat agagtaggct tcatcataac
    33001 ataaggaaag taaatttcat gaatccctcc gaagaaatga ataaccattg ccccccaaga
    33061 agaagattta gcagaacctt taccgaatac agcataagct aatagaattc ccaggcctgg
    33121 tccaggatta gcttccaata ggaagagaat tgacttacca gcttgagcta cctgttctac
    33181 tcccagagga gtaaaaatgc catgattgag ggcattattg aggaaaagga ctttagccgg
    33241 ttcgatgata atattagcca taggaaggag gcgagcattg acaatagcct caacaccatt
    33301 cccaacagct ccagtaagag tcgatacgac tggaccgatt gcgtagaaag ccaaaagcaa
    33361 taatgcaaaa ccaacgagac cagctgagaa gttattaact aacatttcaa atccgggacg
    33421 aattttttct tggaacttct catcaaattt cttgatagtc catcctccca gtgggcccat
    33481 taccatagct ccgataaaca taggaacact agaacctgtg attgcaccaa cagtagcaat
    33541 agctcctaca acggcaccac gttggccatg gatcatatat ccacctgtgt aaccaatcag
    33601 gattggcaat aaatacgtta acataggacc aacaacagta gctaactgtt catttggcag
    33661 atagccatca gcgataaaga gggcagtcaa tactccccaa gcaataaatg ctccaatatt
    33721 gggcataacc atatttgaaa gcgatgtccc tagtttttga accctgactt tcaatgatac
    33781 tttttcttcc attagatcat cctccttttc ttaaaactag tatatacaaa gttaaaaacc
    33841 tttaaaacta aagttttgtc acagattttg tgtcaaaaca ttacttttga cgaggctggg
    33901 caaaaaggct taaaaattat aaaacgcatc atatcaggtg tacatgaact acaccccaaa
    33961 agttagacag
//
LOCUS       DBEJAU010000018        33451 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC323 isolate 683620
            SAMN38261939-rid24807223.denovo.018, whole genome shotgun sequence.
ACCESSION   DBEJAU010000018 DBEJAU010000000
VERSION     DBEJAU010000018.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261939
            Sequence Read Archive: SRR26833919
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 33451)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 33451)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576303.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576303.1
            Genome Coverage       :: 154x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/19/2025 01:05:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,121
            CDSs (total)                      :: 2,078
            Genes (coding)                    :: 1,943
            CDSs (with protein)               :: 1,943
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 36
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 72 of 135
            Pseudo Genes (incomplete)         :: 63 of 135
            Pseudo Genes (internal stop)      :: 51 of 135
            Pseudo Genes (multiple problems)  :: 46 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..33451
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261939-rid24807223.denovo.018"
                     /strain="GPSC323"
                     /isolate="683620"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            complement(7..729)
                     /locus_tag="ACL29Z_000913"
     CDS             complement(7..729)
                     /locus_tag="ACL29Z_000913"
                     /EC_number="5.4.99.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397198.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009982 - pseudouridine synthase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pseudouridine synthase"
                     /protein_id="HGR0069244.1"
                     /translation="MRLDKFLVACAVGSRTEVKNLLKAGRVTVNGKKEKSAKLQIDEK
                     IDEIRFDGQVLEYEEFVYYMMNKPKGVISATEDPKHRTVLDLLDDLARSKEVFPVGRL
                     DIDTHGLLLLTNNGQLAHVLLSPKRHVDKTYQAQVKGIMTQEDVETFIKGIPLKDFTC
                     QPARLEILSTDAEKNQSQIRVTIAEGKFHQIKRMVGYCGKEVVDLQRLTMGTLVLDEN
                     LERGKWRRLTKEELEILRANII"
     gene            complement(997..1227)
                     /locus_tag="ACL29Z_000914"
     CDS             complement(997..1227)
                     /locus_tag="ACL29Z_000914"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000901571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GlsB/YeaQ/YmgE family stress response membrane
                     protein"
                     /protein_id="HGR0069245.1"
                     /translation="MLGSMFVGLLVGFLAGAMTNRGERMGCFGKMFLGWIGAFLGHLL
                     FGTWGPVLSGTAIIPAILGAMIVLAIFWRRGS"
     gene            complement(1237..2478)
                     /locus_tag="ACL29Z_000915"
     CDS             complement(1237..2478)
                     /locus_tag="ACL29Z_000915"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000243957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase"
                     /protein_id="HGR0069246.1"
                     /translation="MVLPNFKENLEKYAKLLVANGINVQPGHTLALSIDVEQRELAHL
                     IVKEAYALGAHEVIVQWTDDVINREKFLHAPMERLDNVPEYKIAEMNYLLENKASRLG
                     VRSSDPGALNGVDADKLSASAKAMGLAMKPMRIATQSNKVSWTVAAAAGLEWAKKVFP
                     NAASDEEAVDFLWDQIFKTCRVYEADPVKAWEEHAAILKSKADMLNKEQFSALHYTAP
                     GTDLTLGLPKNHVWESAGAVNAQGEEFLPNMPTEEVFTAPDFRRADGYVTSTKPLSYN
                     GNIIEGIKVTFKDGQIVDITAEKGDQVMKDLVFENAGARALGECALVPDPSPISQSGI
                     TFFNTLFDENASNHLAIGAAYATSVVDGAEMSEEELEAAGLNRSDVHVDFMIGSNQMD
                     IDGIREDGTRVPLFRNGNWAN"
     gene            complement(2500..2652)
                     /locus_tag="ACL29Z_000916"
     CDS             complement(2500..2652)
                     /locus_tag="ACL29Z_000916"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000776615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0069247.1"
                     /translation="MKLRIFAEDKPAKKVFEYQLELADRTILLSTALLSGAIALAGIF
                     SALKEK"
     gene            complement(2673..2951)
                     /locus_tag="ACL29Z_000917"
     CDS             complement(2673..2951)
                     /locus_tag="ACL29Z_000917"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013904578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system YafQ family
                     toxin"
                     /protein_id="HGR0069248.1"
                     /translation="MLKIRYHKQFKKDFKLAMKRGLKAELLEEVLNFLVQEKEHPARY
                     RDHSLTASKHFQGVRECHTQPDWLLVYKVDKSELILNLLRTGSHSDLF"
     gene            complement(2944..3207)
                     /locus_tag="ACL29Z_000918"
     CDS             complement(2944..3207)
                     /locus_tag="ACL29Z_000918"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelB/DinJ family
                     antitoxin"
                     /protein_id="HGR0069249.1"
                     /translation="MSKMSISIRLDSEVKEQAQQVFSNLGMDMTTAINIFLRQAIQYQ
                     GLPFDVRLDENRKLLQALTDLDQNRNMSQSFESVSDLMEDLRA"
     gene            complement(3309..7700)
                     /locus_tag="ACL29Z_000919"
     CDS             complement(3309..7700)
                     /locus_tag="ACL29Z_000919"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000071418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA];
                     GO_function: GO:0008408 - 3'-5' exonuclease activity
                     [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PolC-type DNA polymerase III"
                     /protein_id="HGR0069250.1"
                     /translation="MSNSFEILMNQLGMPAEMRQAPALAQANIERVVVHKISKVWEFH
                     FVFSNILPIEIFLELKKGLSEEFSKTGNKAVFEIKARSQEFSNQLLQSYYREAFSEGP
                     CASQGFKSLYQNLQVRAEGNQLFIEGSEAIDKEHFKKNHLPNLAKQLEKFGFPTFNCQ
                     VEKNDVLTQEQEEAFHAENEQIVQAANEEALRAMEQLEQIALPPAEEKPVFDFQAKKA
                     AAKPKLDKAEITPMIEVTTEENRLVFEGVVFDVEQKVTRTGRVLINFKMTDYTSSFSM
                     QKWVKNEEEAQKFDLIKKNSWLRVRGNVEMNNFTRDLTMNVQDLQEVVHYERKDLMPE
                     GERRVEFHAHTNMSTMDALPEVEEIVATAAKWGHKAVAITDHGNVQSFPHGYKAAKKA
                     GIQLIYGMEANIVEDRVPIVYNEVEMDLSEATYVVFDVETTGLSAIYNDLIQVAASKM
                     YKGNVIAEFDEFINPGHPLSAFTTELTGITDDHVKNAKPLEQVLQEFQEFCKDTVLVA
                     HNATFDVGFMNANYERHDLPKISQPVIDTLEFARNLYPEYKRHGLGPLTKRFGVALEH
                     HHMANYDAEATGRLLFIFIKEVAEKHGVTDLARLNIDLISPDSYKKARIKHATIYVKN
                     QVGLKNIFKLVSLSNTKYFEGVPRIPRTVLDAHREGLILGSACSEGEVFDVVVSQGVD
                     AAVEVAKYYDFIEVMPPAIYAPLIAKEQVKDMEELQTIIKSLIEVGDRLGKPVLATGN
                     VHYIEPEEEIYREIIVRSLGQGAMINRTIGHGEHAQPAPLPKAHFRTTNEMLDEFAFL
                     GEELARKLVIENTNALAEIFEPVEVVKGDLYTPFIDKAEETVAELTYKKAFEIYGNPL
                     PDIVDLRIEKELTSILGNGFAVIYLASQMLVQRSNERGYLVGSRGSVGSSFVATMIGI
                     TEVNPLSPHYVCGQCQYSEFITDGSYGSGFDMPHKDCPNCGHKLSKNGQDIPFETFLG
                     FDGDKVPDIDLNFSGEDQPSAHLDVRDIFGEEYAFRAGTVGTVAAKTAYGFVKGYERD
                     YGKFYRDAEVERLAQGAAGVKRTTGQHPGGIVVIPNYMDVYDFTPVQYPADDVTAEWQ
                     TTHFNFHDIDENVLKLDVLGHDDPTMIRKLQDLSGIDPNKIPMDDEGVMALFSGTDVL
                     GVTPEQIGTPTGMLGIPEFGTNFVRGMVDETHPTTFAELLQLSGLSHGTDVWLGNAQD
                     LIKQGIADLSTVIGCRDDIMVYLMHAGLEPKMAFTIMERVRKGLWLKISEEERNGYIE
                     AMKANKVPEWYIESCGKIKYMFPKAHAAAYVMMALRVAYFKVHHPIYYYCAYFSIRAK
                     AFDIKTMGAGLEVIKRRMEEISEKRKNNEASNVEIDLYTTLEIVNEMWERGFKFGKLD
                     LYRSQATEFLIDGDTLIPPFVAMDGLGENVAKQLVRAREEGEFLSKTELRKRGGLSST
                     LVEKMDEMGILGNMPEDNQLSLFDELF"
     gene            complement(7804..9885)
                     /gene="fusA"
                     /locus_tag="ACL29Z_000920"
     CDS             complement(7804..9885)
                     /gene="fusA"
                     /locus_tag="ACL29Z_000920"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003746 - translation elongation factor
                     activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_process: GO:0006414 - translational elongation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor G"
                     /protein_id="HGR0069251.1"
                     /translation="MAREFSLEKTRNIGIMAHVDAGKTTTTERILYYTGKIHKIGETH
                     EGASQMDWMEQEQERGITITSAATTAQWNNHRVNIIDTPGHVDFTIEVQRSLRVLDGA
                     VTVLDSQSGVEPQTETVWRQATEYGVPRIVFANKMDKIGADFLYSVSTLHDRLQANAH
                     PIQLPIGSEDDFRGIIDLIKMKAEIYTNDLGTDILEEDIPAEYLDQAQEYREKLIEAV
                     AETDEELMMKYLEGEEITNEELKAGIRKATINVEFFPVLCGSAFKNKGVQLMLDAVID
                     YLPSPLDIPAIKGINPDTDAEEIRPASDEEPFAALAFKIMTDPFVGRLTFFRVYSGVL
                     QSGSYVLNTSKGKRERIGRILQMHANSRQEIDTVYSGDIAAAVGLKDTTTGDSLTDEK
                     AKIILESINVPEPVIQLMVEPKSKADQDKMGIALQKLAEEDPTFRVETNVETGETVIS
                     GMGELHLDVLVDRMRREFKVEANVGAPQVSYRETFRASTQARGFFKRQSGGKGQFGDV
                     WIEFTPNEEGKGFEFENAIVGGVVPREFIPAVEKGLVESMANGVLAGYPMVDVKAKLY
                     DGSYHDVDSSETAFKIAASLSLKEAAKSAQPAILEPMMLVTITVPEENLGDVMGHVTA
                     RRGRVDGMEAHGNSQIVRAYVPLAEMFGYATVLRSASQGRGTFMMVFDHYEDVPKSVQ
                     EEIIKKNKGED"
     gene            complement(10310..10780)
                     /gene="rpsG"
                     /locus_tag="ACL29Z_000921"
     CDS             complement(10310..10780)
                     /gene="rpsG"
                     /locus_tag="ACL29Z_000921"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015935 - small ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S7"
                     /protein_id="HGR0069252.1"
                     /translation="MSRKNRAPKRDVLPDPLYNSQLVTRLINRVMLDGKRGTAASIVY
                     GAFEQIKEATGNDALEVFETAMENIMPVLEVRARRVGGSNYQVPVEVRPERRTTLGLR
                     WLVTIARLRGEHTMQDRLAKEILDAANNTGAAVKKREDTHRMAEANRAFAHFRW"
     gene            complement(10800..11213)
                     /gene="rpsL"
                     /locus_tag="ACL29Z_000922"
     CDS             complement(10800..11213)
                     /gene="rpsL"
                     /locus_tag="ACL29Z_000922"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015935 - small ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S12"
                     /protein_id="HGR0069253.1"
                     /translation="MPTINQLVRKPRKSKVEKSKSPALNVGYNSHKKVQTNVSSPQKR
                     GVATRVGTMTPKKPNSALRKFARVRLSNLIEVTAYIPGIGHNLQEHSVVLLRGGRVKD
                     LPGVRYHIVRGALDTAGVNDRKQGRSKYGTKRPKA"
     gene            11630..15427
                     /gene="spuA"
                     /locus_tag="ACL29Z_000923"
     CDS             11630..15427
                     /gene="spuA"
                     /locus_tag="ACL29Z_000923"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001860626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG-anchored pullulanase SpuA"
                     /protein_id="HGR0069254.1"
                     /translation="MRKTPSHTEKKMVYSIRSLKNGTGSVLIGASLVLLAMATPTISS
                     DESTPTTNEPNNRNTTTLAQPLTDTAAGSGKNESDISSPRNANASLEKTEEKPATEPT
                     TSTSPVTTETKTEEPIEDNYFRIHVKKLPEENKDAQGLWTWDDVEKPSENWPNGALSF
                     KDAKKDDYGYYLDVKLKGEQAKKISFLINNTAGKNLTGDKSVEKLVPKMNEAWLDQDY
                     KVFSYEPQPAGTVRVNYYRTDGNYDKKSLWYWGDVKNPSSAQWPDGTDFTATGKYGRY
                     IDIPLNEAAREFGFLLLDESKQGDDVKIRKENYKFTDLKNHSQIFLKDDDESIYTNPY
                     YVHDIRMTGAQHVGTSSIESSFSTLVGAKKEDILKHSNITNHLGNKVTITDVAIDEAG
                     KKVTYSGDFSDTKHPYTVSYNSDQFTTKTSWRLKDETYSYDGKLGADLKEEGKQVDLT
                     LWSPSADKVSVVVYDKNDPDKVVGTVALEKGERGTWKQTLDSTNKLGITDFTGYYYQY
                     QIERQGKTVLALDPYAKSLAAWNSDDAKIDDAHKVAKAAFVDPAKLGPQDLTYGKIHN
                     FKTREDAVIYEAHVRDFTSDPAIAKDLTKPFGTFEAFIEKLDYLKDLGVTHIQLLPVL
                     SYYFVNELKNHERLSDYASSNSNYNWGYDPQNYFSLTGMYSSDPKNPEKRIAEFKNLI
                     NEIHKRGMGAILDVVYNHTAKVDIFEDLEPNYYHFMDADGTPRTSFGGGRLGTTHHMT
                     KRLLVDSIKYLVDTYKVDGFRFDMMGDHDAASIEEAYKAARALNPNLIMLGEGWRTYA
                     GDENMPTKAADQDWMKHTDTVAVFSDDIRNNLKSGYPNEGQPAFITGGKRDVNTIFKN
                     LIAQPTNFEADSPGDVIQYIAAHDNLTLFDIIAQSIKKDPSKAENYAEIHRRLRLGNL
                     MVLTAQGTPFIHSGQEYGRTKQFRDPAYKTPVAEDKVPNKSHLLRDKDGNPFDYPYFI
                     HDSYDSSDAVNKFDWTKATDGKAYPENVKSRDYMKGLIALRQSTDAFRLKSLQDIKDR
                     VHLITVPGQNGVEKEDVVIGYQITAPNGDIYAVFVNADEKAREFNLGTAFAHLRNAEV
                     LADENQAGSVGIANPKGLEWTEKGLKLNALTATVLRVSQNGTSHESTAEEKPDSTPSK
                     PEHQNEASHPAHQNLAPEARPDSTKPDAKVADAENKPSQATADSQAEQPAQEAQASSV
                     KEAVRNESVENSSKENIPATPDRQAELPNTGIKNENKLLFAGISLLALLGLGFLLKNK
                     KEN"
     gene            complement(15527..16576)
                     /locus_tag="ACL29Z_000924"
     CDS             complement(15527..16576)
                     /locus_tag="ACL29Z_000924"
                     /EC_number="1.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000229779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0010181 - FMN binding [Evidence IEA];
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LLM class flavin-dependent oxidoreductase"
                     /protein_id="HGR0069255.1"
                     /translation="MVELGISTFGEITELEGTGQTYSHAERIRQLVAEIELADKVDLD
                     VYGIGEHHRADFAVSAPEIVLAAGAVNTKKIRLTSAVSILSSMDPIRLFQQYATIDAL
                     SNGRAEIMAGRGSFTESFPLFGYDLKDYDSLFDEKLDLLQLVNEKTKLDWQGRLTQTI
                     AGKEVYPRPVQDKLPLWIATGGHVESTVKIAQAGLPIVYAIIGGNPRYFKKLIQAYRE
                     IGSEAGHADKDLKVGAHSWGWIAEDGEQAVKDYFHPTKQVVDAISKDRPHWQELRYEQ
                     YLEQVGSNGAMFVGNPDQVAEKLIRMIEDLGLDRFMLHLPLGSMPHDQVLRAIELFGT
                     QVAPKVRAYFAMKEA"
     gene            complement(16695..18503)
                     /gene="glmS"
                     /locus_tag="ACL29Z_000925"
     CDS             complement(16695..18503)
                     /gene="glmS"
                     /locus_tag="ACL29Z_000925"
                     /EC_number="2.6.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014621492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004360 - glutamine-fructose-6-phosphate
                     transaminase (isomerizing) activity [Evidence IEA];
                     GO_process: GO:1901137 - carbohydrate derivative
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine--fructose-6-phosphate transaminase
                     (isomerizing)"
                     /protein_id="HGR0069256.1"
                     /translation="MCGIVGVVGNTNATDILIQGLEKLEYRGYDSAGIFVLDGADNHL
                     VKAVGRIAELSAKTAGVEGTTGIGHTRWATHGKPTEDNAHPHRSETERFVLVHNGVIE
                     NYLEIKEEYLAGHHFKGQTDTEIAVHLIGKFAEEEGLSVLEAFKKALHIIRGSYAFAL
                     VDSQDPEVIYVAKNKSPLLIGLGEGYNMVCSDAMAMIRETNQYMEIHDQELVIVKADS
                     VEVQDYDGNSRERASYTAELDLSDIGKGTYPYYMLKEIDEQPTVMRKLIQAYTDEAGQ
                     VVVDPDIIKAVQDADRIYILAAGTSYHAGFASKKMLEELTDTPVELGISSEWGYGMPL
                     LSKKPLFIFISQSGETADSRQVLVKANEMGIPSLTVTNVPGSTLSREANYTMLLHAGP
                     EIAVASTKAYTAQIAALAFLAKAVGEANGNAKAQAFDLVHELSIVAQSIESTLSEKET
                     IEAKVRELLETTRNAFYIGRGQDYYVAMEASLKLKEISYIQCEGFAAGELKHGTIALI
                     EEGTPVLALLSDPVLANHTRGNIQEVAARGAKVLTIAEENVAKDTDDIVLTTVHPYLS
                     PISMVVPTQLVAYFATLHRGLDVDKPRNLAKSVTVE"
     gene            complement(18695..20074)
                     /gene="bglA"
                     /locus_tag="ACL29Z_000926"
     CDS             complement(18695..20074)
                     /gene="bglA"
                     /locus_tag="ACL29Z_000926"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000943526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-glucosidase"
                     /protein_id="HGR0069257.1"
                     /translation="MLRFPKDFVWGSSTSGPQTEGRVAGDGKGDNLWDYWFQVEPNRY
                     YNGIGSDKTSTFYENWERDIELLLETGHTAFRTSIQWSRIFPQGCGKVNTQGVDFYRK
                     VFEAIKAKGIRLLVNLYHFDLPFALQEDGDGWENKATVSAYEDYARFCFETYGDLVDQ
                     WITFNEPIVPVEFGYFYDAHYPHKVDAEAAVKVAYHTQLASSRAVKACHELLPDSKIG
                     IVLNLTPAYPRSQHPADVKAARIAALFQAQSFLDPSVLGTYPQELVEILHEHGLLPDA
                     TEEELELIRDNTVDFLGVNYYQPLRVMAPRFAKHPESPLLPEHFYEPYVMPGRKINSH
                     RGWEIYEQGIYDIAQNIKENYGNIEWMLTENGMGVEGEEKFRQDGMIQDDYRIDFVKG
                     HLRELHRAIEDGANCKGYLIWTFIDCWSWLNSYKNRYGLVELDLETQERRLKKSGHWF
                     KELSDNNGF"
     gene            complement(20173..22026)
                     /locus_tag="ACL29Z_000927"
     CDS             complement(20173..22026)
                     /locus_tag="ACL29Z_000927"
                     /EC_number="6.1.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000814078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0002161 - aminoacyl-tRNA editing activity
                     [Evidence IEA];
                     GO_function: GO:0004812 - aminoacyl-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0004827 - proline-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006418 - tRNA aminoacylation for protein
                     translation [Evidence IEA];
                     GO_process: GO:0006433 - prolyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="proline--tRNA ligase"
                     /protein_id="HGR0069258.1"
                     /translation="MKQSKMPIPTLREMPSDAQVISHALMLRAGYVRQVSAGVYSYLP
                     LANRVIEKAKNIMRQEFEKIGAVEMLAPALLSAELWRESGRYETYGEDLYKLKNREKS
                     DFILGPTHEETFTAIVRDSVKSYKQLPLNLYQIQPKYRDEKRPRNGLLRTREFIMKDA
                     YSFHANYDSLDSVYDEYKAAYERIFTRSGLDFKAIIGDGGAMGGKDSQEFMAITSART
                     DLDRWVVLDKSVASFDEIPAEVQEEIKAELLKWIVSGEDTIAYSSESSYAANLEMATN
                     EYKPSNRVVAEEEVTRVATPDVKSIDEVAAFLNVPEEQTIKTLFYIADGELVAALLVG
                     NDQLNEVKLKNHLGADFFDVASEEEVANVVQAGFGSLGPVGLPENIKIIADRKVQDVR
                     NAVVGANEDGYHLTGVNPGRDFTAEYVDIREVREGEISPDGQGVLNFARGIEIGHIFK
                     LGTRYSASMGADVLDENGRAVPIIMGCYGIGVSRLLSAVMEQHARLFVNKTPKGEYRY
                     AWGINFPKELAPFDVHLITVNVKDEEAQALTEKLEASLMGAGYEVLTDDRNERVGVKF
                     SDSDLIGLPIRITVGKKAADGIVEVKIKATGDTIEVHADNVLETLEILSKK"
     gene            complement(22039..23298)
                     /gene="rseP"
                     /locus_tag="ACL29Z_000928"
     CDS             complement(22039..23298)
                     /gene="rseP"
                     /locus_tag="ACL29Z_000928"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000900658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0004222 - metalloendopeptidase activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RIP metalloprotease RseP"
                     /protein_id="HGR0069259.1"
                     /translation="MLGILTFILVFGIIVVVHEFGHFYFAKKSGILVREFAIGMGPKI
                     FAHIGKDGTAYTIRILPLGGYVRMAGWGDDTTEIKTGTPVSLTLADDGKVKRINLSGK
                     KLDQTALPMQVTQFDFEDKLFIKGLVLEEEKTFAVDHDATVVEADGTEVRIAPLDVQY
                     QNATIWGKLITNFAGPMNNFILGVVVFWVLIFMQGGVRDVDTNQFHIMPQGALAKVGV
                     PETAQITKIGSHEVSNWESLIQAVETETKDKTAPTLDVTISEKGSDKQVTVTPEDSQG
                     RYLLGVQPGVKSDFLSMFVGGFTTAADSALRILSALKNLIFQPDLNKLGGPVAIFKAS
                     SDAAKNGIENILYFLAMISINIGIFNLIPIPALDGGKIVLNILEAIRRKPLKQEIETY
                     VTLAGVVIMVVLMIAVTWNDIMRLFFR"
     gene            complement(23320..24123)
                     /locus_tag="ACL29Z_000929"
     CDS             complement(23320..24123)
                     /locus_tag="ACL29Z_000929"
                     /EC_number="2.7.7.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000189872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004605 - phosphatidate
                     cytidylyltransferase activity [Evidence IEA];
                     GO_process: GO:0016024 - CDP-diacylglycerol biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatidate cytidylyltransferase"
                     /protein_id="HGR0069260.1"
                     /translation="MTQDLQKRTLFAGIALAIFLPILMIGGLLLQIAIGIIAMLAMHE
                     LLKMRGLETMTMEGLLTLFATFALTIPLENYLTFLPVDGNVVAYSVLISIMLGTTVFS
                     KSYTIEDAVFPLAMSFYVGFGFNALLDARVAGLDKALLALCIVWATDSGAYLVGMNYG
                     KRKLAPRVSPNKTLEGALGGILGAILVTIIFMIVDSTVALPYGIYKMSVFAIFFSIAG
                     QFGDLLESSIKRHFGVKDSGKFIPGHGGVLDRFDSMLLVFPIMHLFGLF"
     gene            complement(24132..24890)
                     /locus_tag="ACL29Z_000930"
     CDS             complement(24132..24890)
                     /locus_tag="ACL29Z_000930"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000466694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016765 - transferase activity,
                     transferring alkyl or aryl (other than methyl) groups
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="isoprenyl transferase"
                     /protein_id="HGR0069261.1"
                     /translation="MFGFFKKDKAVEVEVPTQVPAHIGIIMDGNGRWAKKRMQPRVFG
                     HKAGMEALQTVTKAANKLGVKVITVYAFSTENWTRPDQEVKFIMNLPVEFYDNYVPEL
                     HANNVKIQMIGETDRLPKQTFEALTKAEELTKNNTGLILNFALNYGGRAEITQALKLI
                     SQDVLDAKINPGDITEELIGNYLFTQHLPKDLRDPDLIIRTSGELRLSNFLPWQGAYS
                     ELYFTDTLWPDFDEAALQEAILAYNRRHRRFGGV"
     gene            complement(25121..25693)
                     /locus_tag="ACL29Z_000931"
     CDS             complement(25121..25693)
                     /locus_tag="ACL29Z_000931"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001098890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyltransferase family protein"
                     /protein_id="HGR0069262.1"
                     /translation="MNTVKNKQEILEAFRESPDMMAILTIIRDLGLKDSWLAAGSVRN
                     FIWNLLSDKSPFDHETDIDVIFFDPDFSYEETLLLEKKLREDFPQYQWELKNQVYMHQ
                     HSPHTASYTSSRDAMSKYPERCTAVGLRLNEESDFELYVPYGLEDILNFQVRPTPHFL
                     ENEDRMELYQTRLSKKNWQEKWKNLIFKNT"
     gene            complement(25674..26672)
                     /gene="ruvB"
                     /locus_tag="ACL29Z_000932"
     CDS             complement(25674..26672)
                     /gene="ruvB"
                     /locus_tag="ACL29Z_000932"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008808138.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0009378 - four-way junction helicase
                     activity [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction branch migration DNA helicase
                     RuvB"
                     /protein_id="HGR0069263.1"
                     /translation="MSRILDNEMMGDEELVERTLRPQYLREYIGQDKVKDQLQIFIEA
                     AKMRDEALDHVLLFGPPGLGKTTMAFVIANELGVNLKQTSGPVIEKAGDLVAILNELE
                     PGDVLFIDEIHRLPMSVEEVLYSAMEDFYIDIMIGAGEGSRSVHLELPPFTLIGATTR
                     AGMLSNPLRARFGITGHMEYYAHADLTEIVERTADIFEMEITHEAASELALRSRGTPR
                     IANRLLKRVRDFAQIMGNGVIDDIITDKALTMLDVDHEGLDYVDQKILRTMIEMYSGG
                     PVGLGTLSVNIAEERETVEDMYEPYLIQKGFIMRTRSGRVATAKAYEHLGYEYSEK"
     gene            26806..26898
                     /locus_tag="ACL29Z_000933"
     CDS             26806..26898
                     /locus_tag="ACL29Z_000933"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system Fst family toxin"
                     /protein_id="HGR0069264.1"
                     /translation="MMELVLKTIIGPIVVGVVLRIVDKWLNKDK"
     gene            27239..27331
                     /locus_tag="ACL29Z_000934"
     CDS             27239..27331
                     /locus_tag="ACL29Z_000934"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system Fst family toxin"
                     /protein_id="HGR0069265.1"
                     /translation="MMELILKTIIGPIVVGVILRLVDKWLNKDR"
     gene            complement(28183..28599)
                     /locus_tag="ACL29Z_000935"
     CDS             complement(28183..28599)
                     /locus_tag="ACL29Z_000935"
                     /EC_number="2.3.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0016746 - acyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HGR0069266.1"
                     /translation="MITIKKQEFVKLEDVLHLYQAVGWTNYTHQPEMLEQALSHSLAI
                     YVALDGDAVVGLIRLVGDGFSSVLVQDLIVLPIYQRQGIGSALMKEALEDYKDAYQVQ
                     LVTEQTERTLGFYCSMGFEILSTYDCIGMTWINREK"
     gene            complement(28611..29306)
                     /locus_tag="ACL29Z_000936"
     CDS             complement(28611..29306)
                     /locus_tag="ACL29Z_000936"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001144916.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family protein"
                     /protein_id="HGR0069267.1"
                     /translation="MPVNEYGQMIGESMEGYTPGELPSIDFLEGRYARIEALSVEKHA
                     EDLLAVYGPDTPREMWTYLFQEPVADMEELVSLLNQMLARKDRFYYAIIDRSTGKVLG
                     TFSLMRIDQNNRVIEVGAVTFSPELRGTRIGTEAQYLLARYVFEELNYRRYEWKCDAF
                     NLPSRRAAERLGFIYEGTFRQAVVYKGRTRDTDWLSMTDKDWPKVKDRLETWLRPENF
                     DKNGQQYKSLREL"
     gene            complement(29533..30594)
                     /locus_tag="ACL29Z_000937"
     CDS             complement(29533..30594)
                     /locus_tag="ACL29Z_000937"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001260285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0015969 - guanosine tetraphosphate
                     metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GTP pyrophosphokinase family protein"
                     /protein_id="HGR0069268.1"
                     /translation="MRTQSHKEIVEEYSASRGSYEDCLNYVENTVKNIIKSQSINVHE
                     IIGRVKTVESLEGKVKRKNYSNLAEITDLCGIRIITYFSDDVDKIAELISQEFEVDVE
                     NTIDKRKSEDPTKFGYVSLHYVVGLKEENTSPTLYGRFKNIKLEIQIRTVMQHAWAEI
                     EHDLGYKSKEDIPDQYRRQFARLAGLIELADDDFVQLKNNINNYEQEIKKKLPTSKKE
                     LPIDSSTLMTYVKEDQNYIELLNTIKSSDMDIDFNIDSSFLSTMIQRAKKLDLRTIGD
                     IAELFEKYKDIFLKVLRIEEDIEPCMSISALTPLLHITNVLESVNNINISDEEFMKVS
                     DDEFSDVFGISYPIDVYEG"
     gene            complement(30655..33156)
                     /gene="leuS"
                     /locus_tag="ACL29Z_000938"
     CDS             complement(30655..33156)
                     /gene="leuS"
                     /locus_tag="ACL29Z_000938"
                     /EC_number="6.1.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014639013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004823 - leucine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006429 - leucyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="leucine--tRNA ligase"
                     /protein_id="HGR0069269.1"
                     /translation="MSFYNHKEIEPKWQGYWAEHHTFKTGTDASKPKFYALDMFPYPS
                     GAGLHVGHPEGYTATDILSRYKRAQGYNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTA
                     ENIANFKRQINALGFSYDWDREVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVE
                     ELGTAIANEEVLPDGTSERGGYPVVRKPMRQWMLKITAYAERLLNDLDELDWPESIKD
                     MQRNWIGKSTGANVTFKVKGTDKEFTVFTTRPDTLFGATFTVLAPEHELVDAITSTEQ
                     AEAVADYKHQASLKSDLARTDLAKEKTGVWTGAYAINPVNGKEIPIWIADYVLASYGT
                     GAVMAVPAHDQRDWEFAKQFDLPIVEVLEGGNVAEAAYTEDGLHVNSDFLDGLNKEDA
                     IAKIVAWLEEKGCGQEKVTYRLRDWLFSRQRYWGEPIPIIHWEDETSTAVPETELPLV
                     LPVTKDIRPSGTGESPLANLTDWLEVTREDGVKGRRETNTMPQWAGSSWYYLRYIDPH
                     NTEKLADEDLLKQWLPVDIYVGGAEHAVLHLLYARFWHKFLYDLGVVPTKEPFQKLFN
                     QGMILGTSYRDHRGALVATDKVEKRDGSFFHVETGEELEQAPAKMSKSLKNVVNPDDV
                     VEQYGADTLRVYEMFMGPLDTSIAWSEEGLEGSRKFLDRVYRLITSKEIVAENNGALD
                     KVYNETVKAVTEQIESLKFNTAIAQLMVFVNAANKEEKLYVDYAKGFIQMIAPFAPHL
                     AEELWQTVAATGDSISYVAWPTWDESKLVEDEIEIVVQIKGKVRAKLMVAKDLSREEL
                     QEIALADEKVKAEIDGKEIVKVISVPNKLVNIVVK"
BASE COUNT         9749 a         7846 c         6236 g         9620 t
ORIGIN      
        1 actaaattaa ataatattag cgcggagaat ttctaattct tccttggtca agcgacgcca
       61 tttccctcgt tccaggttct catctaatac taaagttccc atagtcaatc gttgcaagtc
      121 caccacttcc ttgccacagt agcccaccat acgcttgatc tgatgaaact tcccttctgc
      181 aatggtcaca cggatttggc tctgattctt ttctgcatct gtggaaagaa tctccagtct
      241 agcgggctga caggtaaagt ctttgagcgg aatgcccttg ataaatgtct ccacatcttc
      301 ttgggtcata attcccttga cctgagcctg ataagtcttg tccacatgac gcttgggcga
      361 aagaagaaca tgagccagct gaccattatt ggtcaagagc aaaagaccat gcgtgtcaat
      421 atccaagcgt cctactggaa aaacttcctt actccgcgcc aagtcatcca acaagtccag
      481 aacggttctg tgcttgggat cctcagtcgc tgagataact cctttgggct tgttcatcat
      541 gtagtagaca aactcttcat actccaacac ttgcccatca aagcgaatct catctatttt
      601 ttcatcaatc tgcaatttag ctgatttttc ttttttacca tttacagtca cgcgcccagc
      661 cttgagcaag tttttgacct cagtccgact tcccaccgca caggcaacta aaaatttatc
      721 taatctcata gaactattat atcatatcaa aaggaggcta gtacaatgac caacctcctt
      781 ttcgtttcat actcttcaaa aatctcttca aaccgcgtca acgtcgcctt gccgtatata
      841 tgttactgac ttcgtcagtt ctatctgcaa cctcaaaaca gtgtttttag ctgacttcgt
      901 cagttctatc tgcaacctca aagcagtgct ttgagcaacc tgcggctaat ttcctagttt
      961 gctctttgat tttcattgag tatcagattt aggaaattaa cttcctcgtc tccaaaaaat
     1021 agctaaaaca atcatggctc ctaaaatcgc tgggataata gctgttcctg ataaaactgg
     1081 cccccaagtt ccaaagagca agtgacctag aaaggctccg atccaaccga gaaacatttt
     1141 tccaaaacat cccattcgct ctccacgatt ggtcatagca cctgctaaaa atcccactag
     1201 gagaccaacg aacatacttc ctaacatatt atctccttaa tttgcccaat tcccattacg
     1261 gaaaagaggt acccgcgttc catcctcacg aataccatcg atatccattt ggttagaacc
     1321 aatcataaag tctacgtgaa catctgaacg gttaagccct gcagcttcaa gctcctcttc
     1381 gctcatctcc gctccatcaa caacgctagt cgcataggct gcaccgatag ccaagtggtt
     1441 tgacgcattt tcatcgaaaa gggtgttaaa aaaggtaatg cctgactgag aaattggact
     1501 tggatctggt accaaggcac attcacccaa ggcacgcgca cccgcatttt caaagacaag
     1561 gtctttcata acctgatcac ccttctcagc agtgatatct acgatttgtc catccttaaa
     1621 ggtcacctta atgccttcaa tgatatttcc gttgtagcta agcggttttg tagaagtgac
     1681 ataaccatct gcacgacgga agtcaggcgc tgtgaagacc tcttctgtcg gcatatttgg
     1741 caagaattct tcgccctgtg cattgacagc accagctgat tcccaaacgt ggttctttgg
     1801 caaaccaagt gttaaatctg ttcctggcgc tgtgtagtga agggctgaaa attgctcctt
     1861 attaagcata tcggccttgc tcttgagaat ggctgcatgt tcctcccaag ccttaacagg
     1921 atctgcttcg tagacacgac aagttttgaa gatttgatcc caaaggaaat caactgcttc
     1981 ttcgtcgctc gcagcatttg ggaagacttt cttagcccac tcaagtccag cagcggctgc
     2041 tacagtccag ctaaccttgt tagattgagt tgcgattcgc attggcttca tggcaagtcc
     2101 catagcttta gcagaagctg aaagcttgtc agcgtccact ccgttcaagg cacctggatc
     2161 agatgaacga accccaagac ggctagcctt gttctccaag agatagttca tctcagcaat
     2221 cttgtattct ggcacattgt ccaaacgctc catcggggca tggaggaatt tctcacggtt
     2281 aatcacatca tctgtccact gaacgatgac ctcatgcgca cccaaggcat aagcttcttt
     2341 cacgattaga tgtgccaatt cacgttgctc cacatcaata gagagagcca aagtgtgacc
     2401 aggttgcacg ttaattccgt tcgcaaccaa caatttcgca tatttttcta gattttcttt
     2461 aaaatttggt aaaaccattc tgttttctct tttctatttt tatttttctt tcaaggcaga
     2521 aaagattcct gctaaagcaa tagcacctga caagagtgct gtcgatagaa gaattgtacg
     2581 atcagcaagt tctaattgat attcaaatac cttcttagcc ggcttatctt ccgcaaatat
     2641 tcttagtttc atgagaaccc ccttaaaata gattaaaata aatcactgtg actgcctgtc
     2701 ctcagcaaat ttaaaatcaa ttccgacttg tctactttat aaaccaaaag ccaatctggc
     2761 tgggtatggc attcacgaac tccttgaaaa tgcttggatg ccgtcaatga atgatcacga
     2821 tatctggcag gatgttcttt ttcttgaacc agaaaattca aaacttcttc taataattct
     2881 gccttcaaac cacgcttcat agccaactta aaatcttttt taaactgttt atgataacga
     2941 atcttaagca cgtaagtcct ccatcaaatc tgagactgat tcaaaagact ggctcatatt
     3001 acgattttgg tctaaatccg ttaacgcttg gagcaacttc cgattttcgt ctagtctaac
     3061 atcaaaaggt aatccctgat attgaattgc ctgacgaagg aaaatattaa tagctgttgt
     3121 catatccatt cccagattac taaacacctg ttgggcctgc tccttaacct cactatccag
     3181 acggatgctt atactcatct ttgacatact ctcaccctct ttccatagac tattttaaca
     3241 aaaaagaaag ctaatgtaaa tctattggat atacgttagc ctcttttaat agattattaa
     3301 gcaatttttt aaaacaactc atcaaacaaa ctcaactggt tatcctctgg catatttcca
     3361 agaataccca tctcatccat cttttcaacc aaggttgatg agagtccacc acgcttgcgt
     3421 agttctgttt tagagaggaa ttctccctct tcacgcgccc gcaccagttg cttggcaacg
     3481 ttctctccca gaccatccat tgctacaaat ggtgggataa gggtatcccc gtcgatgagg
     3541 aactctgtcg cctgactacg gtagagatct aatttaccaa acttgaaacc tcgttcccac
     3601 atctcattga caatctcaag agttgtatag agatcgattt ccacattaga ggcttcattg
     3661 ttcttccgtt tttcagagat ttcttccatt ctgcgcttga tgacctccaa gcccgcaccc
     3721 atggtcttga tatcaaaagc cttagcacga atggagaagt aagcacagta gtaataaata
     3781 ggatggtgaa ccttgaagta agctacacgc aaggccatca taacgtaggc tgccgcatgg
     3841 gccttaggga acatgtactt aattttccca caggattcga tataccactc tggcacctta
     3901 ttagccttca tggcttcgat atagccattt ctctcctctt ctgaaatctt tagccacaaa
     3961 cccttacgta cccgttccat aatggtaaag gccatcttag gttccagacc cgcatgcatg
     4021 aggtaaacca tgatgtcgtc ccgacaaccg ataacagtcg ataggtccgc tattccttgc
     4081 ttaatcagat cctgagcatt ccccaaccaa acgtcagtac cgtgggacag accagacagc
     4141 tgaagcaatt ccgcaaaggt tgtcggatgg gtttcgtcta ccattccacg tacgaaattt
     4201 gttccaaact ctggaatccc caacataccc gtaggcgttc caatttgttc aggtgttacc
     4261 cctagtacat cagtcccaga aaagagtgcc atcacgcctt cgtcatccat aggaatttta
     4321 ttagggtcaa taccagacaa atcctgaagt tttcgaatca tggtcggatc atcatgtccc
     4381 agtacatcga gtttgaggac gttctcatcg atatcgtgga agttaaagtg agtggtctgc
     4441 cattcagccg tgacatcatc tgctggatac tggacaggcg taaaatcgta gacatccatg
     4501 tagttcggaa taacaacgat tccccccggg tgttggcctg ttgtccgctt gacacccgcc
     4561 gctccttgag cgaggcgttc tacttctgca tcacgataaa acttgccata atctcgctca
     4621 taacccttga caaatccata ggcagtcttg gcagctaccg taccaaccgt tcccgcacgg
     4681 aaggcatatt cttcaccaaa gatatcacgc acatccaagt gggcgctagg ctgatcttct
     4741 cccgagaagt tcaagtcaat atcaggaacc ttatccccat caaaaccaag gaaggtctca
     4801 aacggaatat cctgtccgtt tttactgagt ttgtgaccac agtttggaca gtccttatgg
     4861 ggcatatcaa atcctgaacc gtacgaacca tctgtgataa actcactgta ctgacactga
     4921 ccacagacat agtgaggaga gagaggattg acctccgtaa tcccaatcat ggtcgcaacg
     4981 aaactagatc cgacagaccc acgagaacca accaaataac cccgttcatt agaacgttgc
     5041 accagcatct gcgatgccag ataaatcaca gcaaatccat tccccagtat ggatgttaat
     5101 tctttttcaa tccgcaaatc aacaatatct ggcagcggat ttccataaat ctcaaaagct
     5161 ttcttatagg tcaactcagc aactgtttct tcagccttgt cgatgaaagg cgtatacaag
     5221 tcacccttaa cgacttcaac gggttcaaat atttctgcca aggcattggt gttttcaata
     5281 accagtttac gagccagttc ctctcccaaa aaggcaaatt catccaacat ctcattagtc
     5341 gttcgaaaat gagcctttgg aagtggtgct ggttgggcat gttcaccatg accgatagtt
     5401 cgattaatca tcgcaccctg tcccaaacta cggacgataa tttcacgata aatctcttct
     5461 tccggttcga tatagtgaac atttcccgta gccagaacag gcttgccaag gcggtctcca
     5521 acctctatca aactcttgat aatggtctgg agttcctcca tatccttgac ctgctctttg
     5581 gcaatcaagg gtgcatagat agccggtggc atgacctcga taaaatcata atacttggcc
     5641 acctcaaccg ccgcatccac accttgagaa acgaccacgt caaaaacttc accctctgaa
     5701 caggctgaac ctaaaatcaa gccctctcga tgggcatcta gaaccgttct cggaatccgt
     5761 ggcactcctt caaaatactt ggtattagac aaggaaacca gcttaaagat attttttaga
     5821 cctacctgat tcttgacata gatggtcgca tgcttgatcc gagctttttt gtaagaatct
     5881 ggactgatta gatcaatgtt gagtctagct aaatcggtca caccatgttt ttctgctacc
     5941 tctttgataa agatgaaaag cagacgacca gtcgcttccg catcgtagtt ggccatgtgg
     6001 tgatgttcca aggccacacc aaaacgcttg gtcaaaggcc ccaaaccatg gcgtttatac
     6061 tcaggataga ggtttctagc aaactccagc gtatcaataa ctggctgact aatctttgga
     6121 agatcatgcc gctcataatt agcattcata aagccaacgt caaaggtagc attgtgggca
     6181 actaggaccg tatccttgca aaattcttgg aattcttgca aaacttgttc tagtggtttg
     6241 gcatttttga catgatcatc tgtaattcca gttaactctg tagtaaaggc tgacaaggga
     6301 tgcccaggat tgataaattc atcaaattca gcaataacat tccccttgta catcttagaa
     6361 gccgcaacct gaatcaagtc attatagata gctgaaagtc ccgtcgtttc cacgtcaaag
     6421 accacgtagg ttgcttctga caagtccatc tccacttcgt tatagacgat agggacacgg
     6481 tcctccacga tattggcttc catcccatag atcagctgga ttcccgcttt cttagccgcc
     6541 ttatagccat gtggaaagga ctggacattc ccatggtccg tgatagcaac cgccttgtgt
     6601 ccccacttag cagctgttgc aacaatctct tcgacctctg gcaaagcatc catagtcgac
     6661 atgttagtat gagcatgaaa ctcaacccga cgctcacctt ctggcatcaa atccttccgc
     6721 tcatagtgaa caacttcctg cagatcctgt acgttcatag tcaaatcgcg tgtgaagtta
     6781 ttcatctcca cattccctcg aactcggagc caagaattct tcttgatgag gtcaaacttc
     6841 tgggcctctt cctcgttttt aacccacttt tgcatagaaa aacttgaagt atagtccgtc
     6901 attttaaagt tgattaaaac acgacctgtt ctagtcactt tttgctccac atcaaaaaca
     6961 accccttcaa ataccagacg attttcctct gtcgtcactt cgatcatagg agtaatctcc
     7021 gccttatcca gcttgggttt agctgcagct tttttcgctt gaaaatcaaa gactggtttc
     7081 tcttccgctg gaggaagtgc tatctgctcc agttgttcca tagcacggag cgcttcctca
     7141 ttggcagctt gaacaatctg ctcattttca gcatgaaagg cctcttcctg ctcttgggtc
     7201 aggacatcat tcttctcgac ttgacagtta aaagttggaa aaccaaactt ttcaagttgt
     7261 ttggctaaat taggaagatg attcttctta aaatgttcct tatcaatcgc ttcagatcct
     7321 tcaataaata gctgattacc ctcagcacga acttgcaaat tttgataaag ggacttaaaa
     7381 ccttgactag cacatggacc ttcagagaaa gcctccctat agtaggactg caagagctga
     7441 tttgaaaatt cttgagaccg agccttaatt tcaaaaacag ctttattgcc tgtcttagaa
     7501 aattcttcgc tcaaaccttt ctttaattct aaaaagattt caatcggtaa aatattagaa
     7561 aatacgaaat gaaactccca taccttacta attttatgaa ccacaactcg ctcaatattg
     7621 gcctgtgcta aagcaggagc ctgtctcatt tcagcaggca tccccaattg attcatcaaa
     7681 atttcaaaac tatttgacat tcattttcct cacattattc ttctactatt ttaccatatt
     7741 tagaggtatt ttctaaagac aaaaggaagc cactaagtga cttccttcta gagtgaggac
     7801 ggattagtct tcacctttat ttttcttaat aatttcttct tgtactgact taggtacatc
     7861 ttcgtagtgg tcaaatacca tcatgaatgt accacgtcct tgagatgcag aacgaagaac
     7921 tgttgcgtaa ccgaacattt cagcaagtgg aacgtaagca cgaacgattt ggctgttacc
     7981 gtgtgcttcc ataccatcta cacgtccacg acgagcagtt acgtgaccca taacatcacc
     8041 aaggttttct tctggaacag tgattgttac aagcatcatt ggttcaagga tagctggttg
     8101 tgctgattta gcagcttctt taagggaaag tgatgccgca atcttgaagg cagtttcaga
     8161 tgagtcgaca tcgtgatatg aaccatcata aagcttagct ttaacgtcaa ccattgggta
     8221 acctgcaaga acaccgttag ccatagattc taccaaacct ttttcaaccg ctgggataaa
     8281 ttcacgagga accacaccac cgacgattgc gttttcgaat tcgaatcctt taccttcttc
     8341 gtttggagta aattcaatcc atacatcacc gaattgacct ttaccaccag actgacgttt
     8401 gaagaatcca cgtgcttgag tagaagcgcg gaatgtttca cggtaagata cttgaggagc
     8461 acctacgttc gcttcaactt tgaactcacg acgcatacga tcaacaagga cgtcaaggtg
     8521 aagttcaccc atacctgaga taactgtttc accagtttca acgtttgttt caacgcggaa
     8581 tgttggatct tcttcagcca atttttgaag ggcgataccc atcttgtctt ggtcagcttt
     8641 agattttggc tcaaccatca attggataac tggttctgga acgttgattg actcaaggat
     8701 gattttagct ttttcatctg tcaatgagtc accagttgta gtatctttca aaccaacggc
     8761 agcagcgata tcacctgagt aaacagtgtc gatttcttga cggctgttag cgtgcatttg
     8821 aaggatacgt ccgatacgtt cacgtttacc tttagaagta ttcaatacgt atgaacctga
     8881 ttgaagaaca cctgagtaaa cacggaagaa tgtcaaacga cctacgaatg ggtcagtcat
     8941 gatcttgaag gcaagagctg caaatggctc ttcgtcagat gctggacgaa tttcttcagc
     9001 gtctgtatct gggttaatac ctttgattgc tgggatgtca agtgggcttg gaaggtagtc
     9061 gataaccgca tcaagcatca attgaacacc tttgtttttg aaggctgaac cacacaatac
     9121 tgggaagaat tcaacgttga tagtcgcttt acggatacca gctttcaatt cttcgttagt
     9181 gatttcttca ccttcgaggt atttcatcat caattcttcg tcagtttcag caactgcttc
     9241 aatcaatttt tcacggtatt cttgagcttg gtcaaggtat tcagctggga tgtcttcttc
     9301 aaggatatcc gtaccaaggt cgttagtata gatttcagct ttcatcttga tcaagtcaat
     9361 gataccacgg aagtcatctt cagaaccgat tggcaattgg attgggtgtg catttgcttg
     9421 aagacgatcg tgaagtgtgc ttacagagta aaggaagtca gcaccgattt tgtccatttt
     9481 gttggcaaat acgatacgtg gaactccgta ctcagttgct tgacgccaaa ctgtttcagt
     9541 ttgaggctca acacctgatt gtgagtcaag aacggtaacc gcaccatcca atacacgaag
     9601 agaacgttgt acttcgattg tgaagtccac gtgtcctggt gtgtcgatga tgtttacgcg
     9661 gtggttgttc cattgagctg ttgtcgcagc agatgtgatc gtgataccac gttcttgctc
     9721 ttgctccatc cagtccattt gtgacgcacc ttcgtgagtt tcaccgattt tgtggatttt
     9781 accagtgtag taaagaatac gctcagtagt tgttgtttta ccggcatcga cgtgagccat
     9841 gataccgata ttacgagttt tttcaagtga aaattcgcgt gccatgaggt ttgtttctcc
     9901 tatttatttt tgatttctat tctattataa cacgatttta ataaaaacgg ataggcagga
     9961 cctacccgtt ctcaatgttt tcatgctatt gttggtttca acttacgaga tggtaagctg
    10021 agttatagct aatactaatc gatttagcta atttgaaccc gggctaaagt tagttagccg
    10081 atgtgagctg gaacgggatg ctgcgtgaaa aagataaaac tccttgtatt cgtcgaatac
    10141 tgcgtcagtt tcctattttt accttgcatc cttaccgttc ctagcatcat gatttagttg
    10201 agctcaagct aaaagtctgg agaaaaagat gaatctcatt ggttgcaacc gcaacctgct
    10261 tcgattccct attttctctg ggactttctt aacgctttcg catcctatct taccaacgga
    10321 agtgtgcgaa tgcacggtta gcttcagcca tacggtgagt atcttcacgt ttcttaactg
    10381 ctgcaccagt gttgttagca gcatccaaga tttcttttgc aagacggtct tgcattgtgt
    10441 gttcaccacg aagacgagcg attgttacca accaacgaag tccaagtgtt gtacgacgtt
    10501 ctggacgaac ttcaactggg acttggtagt tagaaccacc aacacgacgt gcacgtactt
    10561 caagtacagg catgatgttt tccatagctg tttcaaatac ttcaagtgca tcgttgccag
    10621 tagcttcttt gatttgctca aaagcaccgt aaacgattga agcagcagta ccacgtttac
    10681 catcaagcat aacgcggttg ataagacgag taactagttg tgaattgtat agcggatctg
    10741 gcaatacgtc acgttttgga gctctatttt tacgactcat ttctctttat cccctttcct
    10801 tatgcttttg gacgtttagt accgtattta gaacggcctt gtttacgatc gttaacacct
    10861 gcagtatcaa gtgcaccacg gacgatatgg taacgtaccc ctggaaggtc ttttacacgt
    10921 ccaccgcgaa gaagcaccac gctgtgctct tgcaagttgt gtccgatacc tgggatgtag
    10981 gcagtaactt cgataaggtt gctcaaacgt acacgagcga atttacgaag ggctgagtta
    11041 ggttttttag gtgtcattgt tccaacacga gttgcaacac cacgtttttg tggtgaagaa
    11101 acgtttgttt gaactttttt atgactattg taaccaacgt tcaaagctgg tgatttagat
    11161 ttttctactt ttgatttacg cggtttgcga accaattggt taattgtagg catctacatt
    11221 ctcctgtgtt tttttatttt tggtgatgat acacttggtg acagatatca tctgtgtgta
    11281 cttttgcaac atttgtcagc acgtccctgt acactcttga gagaccaaaa gtaaaaagta
    11341 ccgtctatta ttgtaacaaa attttccctt gtttgtcaag atatttttct tttttattgg
    11401 taatgttaga gatcaatttc tgaataaaaa tagctgggaa cacatcatct tcctaataat
    11461 acggcttggc ttatgtgaca tttttatctc cgtcatttat actgatatat aaaatagtac
    11521 agaaaacttc tcaaaagtaa gaattttttt cacaaatcaa agaaaacgct tgcatattgt
    11581 tttactacat gctatactga tatagaaatt tattgattgg agaatcatta tgagaaaaac
    11641 accatctcac actgagaaaa aaatggtcta cagcatccgt tccctcaaaa atggaactgg
    11701 ttctgtcctt atcggcgcaa gccttgtctt gcttgccatg gctacaccaa ctatctcatc
    11761 cgacgaaagt acaccaacca ctaacgaacc caacaacaga aatacaacca cccttgccca
    11821 acctcttact gatacagcag ctggctctgg taagaacgaa agtgatattt cttcacctag
    11881 aaatgcaaac gcttccctag agaaaacaga agaaaaacct gcaacagagc caactacttc
    11941 tactagtcca gtaacaactg aaactaagac agaagagccc atcgaagata actacttccg
    12001 tatccatgtc aaaaaacttc ctgaagaaaa caaggatgct caaggactat ggacttggga
    12061 cgatgttgaa aaaccatctg aaaactggcc aaacggagct ttgtccttca aggatgccaa
    12121 gaaagatgac tacggctatt acctagatgt caaattaaag ggagaacaag ccaagaaaat
    12181 tagcttcctc atcaacaata cagctggaaa aaatctaacc ggcgataaat ctgtagaaaa
    12241 actagttcca aaaatgaacg aggcttggtt agaccaagat tacaaggttt tctcttacga
    12301 gccacagcct gcaggaactg ttcgcgtcaa ctactaccgc acagatggca actatgacaa
    12361 gaaatctctc tggtactggg gagatgtaaa aaatccaagt agcgctcaat ggcctgacgg
    12421 aacagacttt acggctacag gcaaatatgg ccgctatatc gacattcctc ttaatgaagc
    12481 cgcaagagaa tttggatttt tattactaga tgagagcaaa caaggagacg acgtgaaaat
    12541 ccgtaaagaa aattataagt tcacagattt gaaaaatcat agccaaattt tcctaaaaga
    12601 cgatgatgaa tcgatttaca caaatccata ctatgtccat gatatccgta tgacaggagc
    12661 ccaacacgta ggcacttcta gcattgaaag tagcttttca acacttgtcg gtgctaaaaa
    12721 agaagatatc ctcaaacact ccaacatcac taatcaccta ggaaacaagg taactattac
    12781 cgatgttgca atcgatgaag ctggtaagaa agtgacctac agcggagatt tctctgacac
    12841 aaaacatcct tatactgtta gctacaattc cgaccaattc actaccaaaa caagctggcg
    12901 cctgaaagat gagacataca gctatgatgg caaactggga gctgacctaa aagaagaagg
    12961 aaaacaagtt gatttgaccc tttggtcacc aagtgctgat aaggtttctg ttgttgtcta
    13021 cgacaagaat gaccctgaca aagtagttgg aactgtcgct ctcgaaaaag gggaaagagg
    13081 aacttggaaa caaactctag acagcacaaa caaactcgga atcacagatt tcactggcta
    13141 ctattatcaa taccaaatcg agcgtcaagg taaaactgtt cttgcactcg atccttacgc
    13201 taaatctctt gctgcttgga atagcgacga tgccaaaatt gacgatgccc ataaagtggc
    13261 taaagccgcc tttgtagatc cagctaaact cggacctcaa gacttgactt atggtaagat
    13321 tcacaatttc aagactcgtg aagacgccgt tatctacgaa gctcatgtgc gtgacttcac
    13381 ttcagatcct gccattgcaa aagacttgac caaaccattt gggacttttg aagccttcat
    13441 tgaaaaacta gactatctca aagacttggg tgtaacccat atccagctcc ttccagtctt
    13501 gtcttactac tttgtcaatg aattgaaaaa ccatgaacgc ttgtctgact acgcttcaag
    13561 caacagcaac tacaactggg gatatgaccc tcaaaactac ttctccttga ctggtatgta
    13621 ctcaagcgat cctaagaatc cagaaaaacg aatcgcagaa tttaaaaacc tcatcaacga
    13681 aatccacaaa cgtggtatgg gagctatcct agatgtcgtt tataaccaca cagccaaagt
    13741 cgatatcttt gaagacctag agccaaacta ctaccacttt atggatgccg atggcacacc
    13801 tcgaactagc tttggtggtg gacgcttggg gacaacccac catatgacca aacggctcct
    13861 agttgactct atcaaatacc tagttgatac ctacaaagtg gatggcttcc gcttcgatat
    13921 gatgggagac catgacgccg cttctatcga agaagcttac aaggctgcac gcgccctcaa
    13981 tccaaacctc atcatgcttg gtgaaggttg gagaacctat gccggtgatg aaaacatgcc
    14041 tactaaagct gctgaccaag attggatgaa acataccgat actgtcgctg tcttttcaga
    14101 tgacatccgt aacaacctca aatctggtta tccaaacgaa ggtcaacctg cctttatcac
    14161 aggtggcaag cgtgatgtca acaccatctt taaaaatctc attgctcaac caactaactt
    14221 tgaagctgac agccctggag atgtcatcca atacatcgca gcccatgata acttgaccct
    14281 ctttgacatc attgcccagt ctatcaaaaa agacccaagc aaggctgaga actatgctga
    14341 aatccaccgt cgtttacgac ttggaaatct catggtcttg acagctcaag gaactccatt
    14401 tatccactcc ggtcaggaat atggacgtac taaacaattc cgtgacccag cctacaagac
    14461 tccagtagca gaggataagg ttccaaacaa atctcacttg ttgcgtgata aggacggcaa
    14521 cccatttgac tatccttact tcatccatga ttcttacgat tctagcgacg cagtcaacaa
    14581 gtttgactgg actaaggcta cagatggtaa agcttatcct gaaaatgtca agagccgtga
    14641 ctatatgaaa ggtttgattg cccttcgtca atctacagat gccttccgac ttaagagtct
    14701 tcaagatatc aaagaccgtg tccacctcat cactgtccca ggccaaaatg gtgtggaaaa
    14761 agaggatgta gtgattggct accaaatcac tgctccaaac ggtgatatct acgcagtctt
    14821 tgtcaatgcg gatgaaaaag ctcgcgaatt taatttggga actgcctttg cacatctaag
    14881 aaatgcggaa gttttggcag atgaaaacca agcaggatca gtcggaattg ccaacccgaa
    14941 aggacttgaa tggactgaaa aaggcttgaa attgaatgcc cttacagcta ctgttcttcg
    15001 agtctctcaa aatggaacta gccatgagtc aactgcagaa gagaaaccag actcaacccc
    15061 ttccaagcct gaacatcaaa atgaagcttc tcaccctgca catcaaaacc tagctccaga
    15121 agctagacct gattctacta aaccagatgc caaagtagct gatgcggaaa ataaacctag
    15181 ccaagctaca gctgattcac aagctgaaca accagcacaa gaagcacaag catcatctgt
    15241 aaaagaagcg gttcgaaacg aatcggtaga aaactctagc aaggaaaata tacctgcaac
    15301 cccagataga caagctgaac ttccaaatac aggaatcaaa aacgaaaaca aactcctatt
    15361 tgcaggaatc agcctccttg cgctccttgg tctcggtttc ttactaaaaa ataaaaaaga
    15421 gaactaaact agccctccta tagaaaaatc ccccaagcat tatagctcgg gggattaatt
    15481 ttcgtacaat atttgttgtc ctaataaact tgattaggat tttttattaa gcctctttca
    15541 tagcaaaata agctcgtact ttgggtgcaa cttgtgttcc gaagagttca atagctctca
    15601 gaacctggtc atgaggcata gaaccaagcg gtagatgaag catgaagcgg tccaatccta
    15661 aatcctctat catgcgaatc aatttttcgg ccacctgatc tggattgcca acaaacatgg
    15721 cgccatttga ccctacctgc tccaaatatt gctcataacg caattcctgc cagtgcggac
    15781 ggtctttgga aatagcatcc accacttgct tagtcggatg gaaataatct ttcaccgcct
    15841 gctcaccatc ttccgcaatc cacccccaag aatgggctcc cactttcaag tctttgtcag
    15901 catggcccgc ttcgcttcca atctcacgat aagcctgaat caacttttta aaataacgtg
    15961 gattaccacc aataatagca tatacaatcg gtagaccagc ctgagcaatc ttcactgttg
    16021 attcgacatg accacctgta gctatccaca agggcaattt gtcctgaact ggacgaggat
    16081 aaacttcttt accagcaatc gtttgagtca atcgaccttg ccagtctaac ttggtctttt
    16141 cattgactaa ctgaagcaag tctaatttct catcaaaaag agagtcgtag tctttcaagt
    16201 cataaccaaa cagagggaaa gattccgtga aagagcccct tccagccata atctccgctc
    16261 gtccatttga caaagcatcg atagtggcat actgttggaa caaacgaatc gggtccatgc
    16321 ttgacagaat gctgactgca ctggtcaaac ggattttctt ggtattgact gccccagcgg
    16381 ccagaacaat ctctggagct gatactgcaa aatccgcccg atggtgctca ccaatcccat
    16441 atacatccaa atcaaccttg tcagccagct caatctctgc caccaactgg cgaatgcgtt
    16501 cagcatgact gtaagtttgt ccagtccctt caagctccgt tatttcccca aatgttgaaa
    16561 ttcccaattc taccattgtg attctccttg tctatctctg tccttcaatt tgaaaaatta
    16621 ttctaacacg aatcttaagt acaagcaacc aatttgctca ttagaaaaag cctagataac
    16681 tagacttttt tagcttattc taccgttact gatttagcaa ggttacgtgg tttatccaca
    16741 tcgaggccac ggtggagggt tgcaaagtaa gcgactaatt gcgttggtac gaccattgaa
    16801 attggtgaga ggtatggatg tacggtcgta aggacgatat cgtcggtatc tttggctaca
    16861 ttctcttctg cgatagtgag gactttggca ccacgggctg cgacctcttg gatatttcca
    16921 cgagtatggt tggcaagaac tggatctgac aagagagcca aaacaggcgt tccttcttca
    16981 atcaaggcaa tggttccgtg cttgagttct cctgccgcaa aaccttcaca ctggatataa
    17041 gaaatctctt tgagtttgag acttgcttcc atggctacgt agtaatcttg accacgtccg
    17101 atgtaaaagg cgttacgagt tgtttcaaga agttcacgaa ccttggcttc aatggtttct
    17161 ttctctgaaa gagttgattc gatagactga gctacgattg acaattcatg aaccaggtca
    17221 aaggcttgcg ctttagcatt accatttgct tctccgactg cttttgcaag gaaggcaagg
    17281 gctgcgattt gcgctgtata ggctttagtt gatgccacgg caatttcagg acctgcgtga
    17341 aggagcatgg tatagttggc ttcacgtgag agggttgaac ctggaacgtt tgtcactgtt
    17401 aagcttggaa ttcccatttc attagccttg accaaaactt gacgactatc cgctgtttca
    17461 ccagattggc tgataaagat gaagagtggt ttcttgctga gaagtggcat accgtagccc
    17521 cactcagatg agattccaag ttcaactggt gtatctgtca attcttccaa cattttctta
    17581 gaagcaaatc ctgcatggta agatgttcca gctgcaagga tgtagatgcg gtctgcgtct
    17641 tgaacagcct taatgatatc tgggtctacg acaacttgac cagcctcatc tgtgtaggct
    17701 tggatgagtt tccgcataac agttggttgc tcgtcaattt ccttgagcat gtagtaagga
    17761 taagttccct taccgatatc tgacaagtca agttccgcag tatagctagc acgttcacga
    17821 ctgttaccat catagtcttg aacttccacg ctatcagcct tgacgattac caactcttgg
    17881 tcatgaattt ccatgtattg gttggtttca cgaatcatag ccatagcatc tgagcagacc
    17941 atattgtagc cttctccaag accaatcaaa agtggtgatt tatttttagc tacgtagatg
    18001 acttcaggat cttgtgagtc aaccaaggca aaggcataag aaccacggat gatgtgaagg
    18061 gcttttttga aggcttcaag aactgagagc ccttcttctt ccgcaaattt tccaatcaaa
    18121 tgaacggcta tttcagtatc tgtctgcccc ttgaagtggt gacctgcaag gtattcttcc
    18181 ttgatttcaa ggtagttctc aatcacccca ttatgcacca agacaaaacg ttctgtctca
    18241 gagcggtgtg ggtgagcatt gtcttccgtt ggtttcccat gagttgccca acgagtatgt
    18301 ccgataccag ttgttccctc aacaccagct gtcttggcag acaattctgc aatacgacca
    18361 accgccttca ccaaatggtt atcagcacca tctaggacaa aaattcccgc agaatcatag
    18421 ccacggtatt caagcttttc aagcccttga atcaaaatat cagttgcatt tgtgtttcca
    18481 acaacaccaa caattccaca catagtatat acgacacagg caagctgtgc tttctcctta
    18541 aaattggtat agtctaattc atcttttata gaatcagcaa aaacagtata tacttgtttc
    18601 tttcacttgt caagagtaaa aattggtata gttcaaatta agctcctgta agcaaaaaac
    18661 tctgaccgat tgggataatc agtcagagtc ctttttaaaa tccattatta tcgcttaatt
    18721 ctttgaacca gtggcctgat ttcttcagac gacgttcttg cgtttccaag tctaattcga
    18781 ccaaaccata gcgattttta tagctgttga gccatgacca gcagtcaata aaggtccaaa
    18841 tcaagtagcc cttacagttg gcaccatctt caatggcacg gtgaagttca cgaagatgac
    18901 cttttacaaa gtcaatacgg taatcatctt gaatcattcc atcttgacgg aatttttctt
    18961 ccccttcaac acccatacca ttctcagtca acatccattc aatattgcca taattttcct
    19021 tgatattttg ggcgatgtca taaatccctt gctcataaat ctcccaacca cggtgagaat
    19081 tgattttacg tccaggcatc acataaggct cgtaaaaatg ttctggtaag agtggactct
    19141 ctggatgctt agcaaatcga ggagccataa cacgcaaagg ttgatagtag ttcacaccaa
    19201 ggaagtccac cgtattatca cgaatgagtt ccaactcttc ctctgtagca tcaggtaaaa
    19261 gaccgtgttc atgcaagatt tctaccaact cctgtggata agtccccaag acagatggat
    19321 ctaagaaaga ttgggcctga aaaagggccg caatacgagc tgccttgaca tcagcaggat
    19381 gctggctacg tggataagcc ggtgtcaagt tgaggacaat cccaatcttg gaatcaggca
    19441 aaagttcatg gcaagcctta acagcccggc tgctggccaa ttgtgtatga taggctacct
    19501 taacagctgc ctctgcatcc accttatgtg gataatgggc atcataaaaa taaccaaatt
    19561 ctacaggaac gatgggctcg ttaaaggtaa tccattgatc cactaaatct ccataagtct
    19621 caaaacaaaa acgagcatag tcttcatagg ctgagactgt cgccttattt tcccaaccat
    19681 caccatcctc ttgaagggca aaaggtaaat caaaatgata gagattgact aacagacgaa
    19741 ttcctttagc cttaatagcc tcaaagacct tacgataaaa atccacacct tgagtgttga
    19801 cttttccaca gccttgtgga aaaatccgtg accactgaat agaagtccga aaggctgtgt
    19861 gaccagtctc taacaaaagc tcaatatccc gctcccaatt ttcataaaaa gtcgatgtct
    19921 tatctgaacc aatcccatta tagtaacgat ttggctccac ttggaaccag taatcccaga
    19981 gattgtctcc cttaccgtca ccagctacac gtccttctgt ctgcggtcca gaagtagagg
    20041 atccccagac aaaatccttt ggaaatctta gcatacattt acctctttat ctactcattt
    20101 ctcccattat acagaaaaaa caaggtaaaa actagttaca ttttttcctt gtttttcttc
    20161 tgattatagt ttttatttct tgcttaggat ttcaagcgtt tcaagcacgt tatctgcatg
    20221 aacctcaatg gtgtcaccag ttgccttgat cttaacttct acaatgccat cggccgcttt
    20281 tttaccaaca gtgatacgga ttggaagacc aatcaagtca ctatcgctaa atttaacacc
    20341 gacacgttcg ttacggtcat ctgtcaagac ttcataacca gctcccatca agcttgcttc
    20401 aagtttttct gtcaaggctt gcgcttcttc atccttgaca ttgacagtaa tcaaatgcac
    20461 atcaaatggt gccaattctt tagggaaatt gattccccaa gcgtaacggt attcaccttt
    20521 tggcgttttg ttaacaaaga ggcgagcgtg ttgctccatc actgctgaaa gaagacggct
    20581 gacaccgata ccgtaacatc ccatgatgat tggcacagca cgaccatttt catccaagac
    20641 atctgctccc atgcttgctg aatagcgagt tccgagtttg aaaatatgac cgatctcaat
    20701 accacgcgca aagttaagga caccttgtcc atctggggaa atttcaccct cacgaacttc
    20761 acggatatcc acatattctg cagtaaaatc acggcctggg ttcacaccag tcaagtggta
    20821 gccatcttcg ttagcaccga caactgcatt gcgaacatct tgtaccttac gatctgcaat
    20881 aattttaata ttctctggca aaccaactgg tccaagtgaa ccaaatcctg cttgaacaac
    20941 attcgccact tcttcttcgc tagcaacgtc aaagaaatct gctcccaagt gatttttcaa
    21001 cttgacttcg ttaagttggt catttccaac tagaagggct gcaacaagct cgccatctgc
    21061 aatgtagaag agggttttaa tcgtttgttc ttctggaaca ttgaggaagg ctgcaacttc
    21121 atcaattgat ttaacatctg gcgttgcaac acgagtaact tcttcttcag cgacaacacg
    21181 gttgcttggt ttgtactcgt ttgttgccat ttctaagtta gctgcatagc tagactcact
    21241 tgagtaagca atggtatctt caccagagac tatccatttg agcaattctg ccttgatttc
    21301 ttcttgcact tctgcaggaa tttcgtcaaa tgaggcaact gacttgtcca agacaaccca
    21361 gcggtcaagg tctgtacgag cagatgtaat ggccataaat tcttggctat ccttaccacc
    21421 catggctcca ccgtcaccaa taatagcctt gaagtctaaa ccactacgag tgaaaatacg
    21481 ctcataggct gctttgtact catcataaac actatccaaa ctatcatagt tagcgtggaa
    21541 actataagca tccttcatga taaactcacg tgtacgaaga agtccattac gtgggcgttt
    21601 ttcatcacga tacttgggct gaatttgata aaggttgagt ggcaattgct tgtaagattt
    21661 aacagaatca cggacaatag ctgtaaaggt ttcttcgtga gttggaccta agataaagtc
    21721 tgatttttca cggtttttta gtttgtaaag gtcttcacca taggtttcgt aacgacctga
    21781 ttcacgccac aattctgcac taagaagggc aggagccaac atctcaacag caccaatctt
    21841 ttcgaattct tggcgcatga tgtttttagc tttttcaatc acacggttgg caagtggtag
    21901 ataagaataa acacctgctg aaacttggcg aacataacca gcacgcaaca taagagcatg
    21961 gctgataact tgagcatcgc ttggcatttc gcgaagcgtt gggataggca ttttactttg
    22021 tttcataata ttcctcgatt atctaaaaaa gagtcgcata atgtcattcc aagtcacagc
    22081 aatcatcaag acaaccatga tgaccactcc ggccaaggtg acataggttt caatttcttg
    22141 tttcaatggt ttgcggcgga tggcttctag gatattgagc acaatcttac caccatccaa
    22201 ggctggaatc ggaataagat taaaaatccc aatattgatg gaaatcattg ccaagaagta
    22261 caagatattc tcaattccat ttttagcagc atcactactt gccttaaaga tagcaacagg
    22321 tccacccaac ttgttcaaat ccggttggaa aatcagattt ttcagagctg agagaattcg
    22381 gagagctgag tcagcagcag ttgtaaaacc acctacaaac atggatagaa aatctgactt
    22441 aacccccggt tgaacaccta gaaggtaacg accttgacta tcttcgggtg taacagtgac
    22501 ttgtttgtca ctcccctttt cagaaatagt cacatccaaa gtcggtgccg tcttatcttt
    22561 ggtttctgtt tccacagctt ggatcaagct ttcccagttg ctaacctcat gtgagccaat
    22621 cttggtaatt tgtgccgttt ctggtactcc taccttggcc aaggcacctt ggggcatgat
    22681 atggaactga ttggtatcaa catctctgac accaccctgc ataaagatta aaacccaaaa
    22741 aacaacgaca cctaagataa aattgttcat aggacctgca aaattggtaa tcagtttgcc
    22801 ccagatagtc gcattttgat attgaacatc taaaggtgca atccgaacct cagtaccatc
    22861 tgcttccaca accgttgcat cgtgatccac tgcaaatgtt ttttcttctt ccagaaccaa
    22921 tcctttgata aagagcttgt cttcaaaatc aaactgggtc acctgcatag ggagggctgt
    22981 ttgatccaat tttttacctg agagattgat gcgtttaacc ttaccatcat cagcaagtgt
    23041 caaactaaca ggcgttcctg tcttgatttc agttgtatca tcaccccaac cggccatgcg
    23101 gacatagcca cccagaggca agattcgaat ggtataggcc gttccatcct tgccaatgtg
    23161 agcaaagatt ttaggtccca taccgatggc aaattcacgt actaaaatcc ctgatttctt
    23221 ggcaaagtag aagtgcccga actcgtgcac cactacaata atcccaaaaa ccagaataaa
    23281 ggttaaaatt ccaagcatag tgtttcctcc gtcttttgat taaaagagtc caaataagtg
    23341 catgattgga aatacaagca acatactatc gaaacgatcc aaaacaccac catgtccagg
    23401 gataaatttc ccagaatcct taacaccaaa atgacgtttg atcgaacttt ctagtaaatc
    23461 accaaattgt ccagcaatgc taaagaaaat agcaaagact gacatcttgt aaattccata
    23521 tggaagagca actgtactgt caactatcat aaagataatg gttactaaaa ttgctcctaa
    23581 aataccaccc aaggcaccct caagggtttt attaggcgat acccttggtg ctaactttcg
    23641 tttcccatag ttcatcccaa caagataggc accactgtct gtcgcccaga cgatacacaa
    23701 ggctaagaga gccttgtcca aacctgcaac acgagcatct agtaaagcat taaatccaaa
    23761 gcccacgtag aagctcatag caagagggaa aaccgcatcc tcaatcgtat aagacttgct
    23821 aaaaacggtc gttcctaaca tgattgaaat caaaacacta taggcaacca cattcccatc
    23881 aactggcaaa aaagtcaggt aattctccaa gggaatggtc aatgcaaagg ttgcaaagag
    23941 ggtcaagagg ccctccatcg tcatggtctc tagacctctc atcttcaaaa gttcatgcat
    24001 ggctagcatg gctatgattc cgattgctat ctgaagcaag aggcccccaa tcattaaaat
    24061 tggtaggaaa atagccaggg caatccctgc aaacaaggtt cttttctgta aatcctgggt
    24121 catatttcct cctaaactcc tccaaatcgg cgatgacgac gattataggc aagaatagct
    24181 tcctgcaagg ccgcttcgtc aaaatcaggc cataaggtgt ccgtaaaata aagctcacta
    24241 taggctccct gccatggaag gaaattgctc aaacgtaatt ctccactagt acggataatc
    24301 aagtctgggt ctcgtaagtc cttaggcaaa tgctgagtaa agagatagtt accaatcaat
    24361 tcctctgtga tgtcacctgg gttgattttg gcatctaaaa catcctggga aatcaactta
    24421 agcgcctgtg taatctcagc acgtccacca tagttaagag caaaattaag aatcaatcct
    24481 gtgttgttct tagtcaattc ctcagccttg gttaaagctt caaaggtttg cttaggcagg
    24541 cggtctgtct ccccaatcat ttgaatctta acattattcg catgtagttc cgggacataa
    24601 ttatcataaa actctactgg caagttcatg ataaacttga cttcctgatc tggacgggtc
    24661 cagttttccg tagaaaaagc atagaccgta ataaccttga cgcccagttt gttggctgcc
    24721 ttggtcacgg tttgcaatgc ttccatgccc gccttatgtc caaaaactcg cggttgcata
    24781 cgttttttag cccaacggcc attgccatcc atgatgatgc cgatatgagc aggaacctgt
    24841 gtcggaacct ctacttccac agccttatct ttcttaaaaa atccaaacat gatcttattc
    24901 ctattcaaaa atctatcgtt tcattatacc atatttcccc attttcttct atcactaagc
    24961 tatttattct caggcaccaa gcccattttt caaaaaaata agccgcctga ttgggcgact
    25021 ttatttttat agggagatta ttatgaaaaa gttttaggag tttaagttaa ggtcttctta
    25081 acttatgaac ttagtgtaca ctccctagct taaagtttcc ttaagtattt ttaaaaatca
    25141 aatttttcca tttctcctgc caatttttct tggataaacg tgtttgatag agttccattc
    25201 ggtcttcatt ttctaagaaa tgaggagttg gacgaacttg aaaattcaaa atatcctcca
    25261 aaccataagg tacatagagt tcaaaatctg attcttcatt caagcgcagt ccaactgccg
    25321 tacaccgttc tggatactta ctcatagcat cacgagaact ggtataggaa gcagtgtgag
    25381 gactgtgctg atgcatatag acctgatttt tcaattccca ctggtactga ggaaaatcct
    25441 ctctcagctt tttctccagt aataaggttt cctcataaga aaaatctgga tcaaagaaaa
    25501 tcacatctat atctgtttca tgatcaaaag gggatttgtc tgacaaaaga ttccagatga
    25561 aatttctgac agaacctgct gccaaccacg agtctttcaa accaaggtct cggatgatcg
    25621 tcagaatggc catcatatct ggactttctc taaaagcctc taagatttct tgcttatttt
    25681 tcactgtatt cataacctaa gtgctcatat gccttagcag tcgccacccg tccagaccgt
    25741 gtccgcatga taaaaccttt ttgaatcaag taaggctcat acatatcttc aactgtctca
    25801 cgctcttcgg caatattcac agaaagagtt cctagaccaa caggtcctcc actgtacatc
    25861 tcaatcatgg tacgaaggat tttttgatcc acatagtcca aaccttcatg gtcaacatcc
    25921 agcatagtca aagccttatc ggtaataata tcatcaatta ccccattccc cattatctgg
    25981 gcaaaatcgc gcacgcgctt gaggagacga ttggcaatac gaggggtccc acgactacgt
    26041 agggccaact cagatgctgc ctcatgagtg atttccatct caaaaatatc tgccgtccgc
    26101 tcgacaattt ctgtcaagtc agcatgggca taatactcca tatggcctgt aatcccaaaa
    26161 cgtgcccgta gtggatttga gagcatacca gcccgagtcg tcgcaccaat caaggtaaaa
    26221 ggtggtaact ccaaatgaac actacgacta ccctcaccag ccccaatcat aatatctatg
    26281 tagaagtcct ccatagcact ataaagcacc tcttccactg acattggcaa acgatggatc
    26341 tcgtcaataa agaggacatc tccaggctct aactcattca aaatcgctac caaatcaccc
    26401 gctttttcga taacaggacc agacgtttgc ttgagattga ctcccagttc attggcaatg
    26461 acaaaagcca tggttgtttt cccaagccct ggagggccaa ataagagcac atgatccagc
    26521 gcttcatccc gcattttagc ggcttcgata aagatctgaa gctgatcctt aaccttatcc
    26581 tgaccaatat attcacgtaa atactgagga cggagcgtgc gttctactaa ctcctcatca
    26641 cccatcatct cattatctaa aattctactc atggctctat tatatcaaaa aaacaagcca
    26701 caaacaaaaa agccacctga ttgggtgact cctaagttta gcacttatgt ggtataatat
    26761 tatacgacac tgctacaccg cctacgaaag gaggtgagat agcccatgat ggaattagta
    26821 ctcaaaacta tcatcggacc aattgtggtc ggtgtcgttc ttcgtatagt cgataaatgg
    26881 ctaaacaagg acaaatagtg tcaaaaaaga cctcaagctt atttggtcgt gagcttgggg
    26941 tcttttctag cctatgatat agaactagta ctcaattcct ttttattatc ccatagttca
    27001 cacattttgt caaagtttta tattttcatc cattcagctt ctccaacttt agaatctgtc
    27061 caataaagtt tataagatta agtgaaagtt atcggaaaat gatgtttaaa atagtcccca
    27121 aaagcctgaa atagagcaaa aaactccacc tggttgggtg actcccgagt ttagcactta
    27181 tgtggtataa tattctacgg cactgctaca ccgcttgcga aaggaggtga gatagcccat
    27241 gatggaacta atccttaaaa ctatcatcgg accgattgtg gtcggtgtca tccttcgctt
    27301 agtcgataaa tggctaaaca aagatagata gtgtcaaaaa agaccccaag cttaatgtgg
    27361 aagttagctt ggggtctttt ctagtccatg atatagaact aatccttaat tcctctccat
    27421 tatcccacag ttcacaaaat ttgtcaaaac tttacatcct cagcttctca agctttaacc
    27481 gctttacaac aagactttca attttaagag aaagttaggg attctatcaa tttcatagaa
    27541 attttgattt agtaaacgaa gagacaatct tatatgtcac tcctcattta atacgccact
    27601 actggacaag caaaatcatt attacagcag ttccagtcct tcaattaaca gcaacttaca
    27661 atcaagttga ggacgaactt gctgaagcga caaccgacct atttcttagt catattcgct
    27721 aaaaaaatcc ccgccaaaat ctcaaaaagt ccccgccaat tccccgacca aaatccgaaa
    27781 aataccgaaa aatatcgaaa aattattttt agaatagtcc ccaaaagcct gaaatagagc
    27841 caaaaaactc cacctgattg ggtggagtta agggagatta ttatgaaaaa gaaaagttta
    27901 ggattttatt aaataaagtt aggaggtctt tatttaataa ctatatgata caagacgaag
    27961 cttaaaacta gcttaacttt tctcaaatta taccattttt aaaaaaattt ctatcagcat
    28021 cacctcaccc tacaaaaaag ccacctgatt aggtgacttc attaggagat tatgatgaaa
    28081 aaaagtttta ggatttcatt aaataaagtt aggaggtctt tatttaatga ctatatgata
    28141 ctagaccagc cttaaacttt gcttaagaac aaccaagttt tattattttt ctctgtttat
    28201 ccaagtcatt cctatacaat cataggtgga taagatttca aagcccatag aacaatagaa
    28261 gcccaaggtt ctttctgtct gttctgttac cagctggact tgataggcat ctttgtaatc
    28321 ctctaaagcc tctttcatta gggcactacc aatcccttga cgttgataga ttggtaaaac
    28381 gattaaatcc tgaaccaata ctgatgagaa tccatctcca accaaacgaa tcaagcccac
    28441 cacagcatcg ccatcaagcg ccacataaat cgctaatgaa tgagataagg cctgctccag
    28501 catctctggt tgatgggtat aatttgtcca accgacagcc tgatagagat gcaaaacatc
    28561 ctctagcttg acaaattctt gctttttaat agtaatcatc tcaacacctc ttaaagctct
    28621 ctcaagctct tgtactgctg tccattttta tcaaaatttt caggacgcaa ccatgtttcc
    28681 aaacgatctt tgactttggg ccagtcctta tcagtcatag acaaccaatc cgtatccctc
    28741 gtacgcccct tataaaccac tgcctgacgg aaggttcctt cataaataaa gcccaaacgt
    28801 tctgcagctc gtcttgatgg cagattaaaa gcatcgcatt tccactcata gcgacgatag
    28861 ttaagctctt caaagacata gcgagccagt agatactggg cttctgtccc tatccgtgtc
    28921 cccctgagtt ctggagaaaa agtgacagct cccacttcta ttactcggtt attctggtca
    28981 atgcgcatga gagaaaaagt tcccaaaacc ttaccagttg acctgtctat gattgcatag
    29041 taaaaacggt ccttacgagc caacatctga tttaaaaggc tgaccagttc ctccatgtct
    29101 gctactggtt cctgaaagag gtaggtccac atctcccgag gagtatccgg gccataaaca
    29161 gctaacaaat cctccgcatg tttttctacc gagagagcct ctatccgagc ataacgtcct
    29221 tctaagaaat caatagaagg cagttcacct ggtgtataac cttccattga ctccccaatc
    29281 atctgaccat attcatttac tggcatctta ttctccttgt ttcacttttc aaactttata
    29341 gttgcccata gtatatcata ctttcataag aagattcaaa aaatcctcca gattctactc
    29401 tgaaggattt atttcttatc taacaacgat attgacgagt ttagttacct tcactttaga
    29461 aagagcaaca ctacgaatta ttcaacttag tcaaatagga aacccctctt ttcatattta
    29521 aaaaattact ttttaacctt cataaacatc aattgggtac gatataccaa atacatctga
    29581 aaattcatca tcagaaactt tcataaattc ttcatcagaa atattaatat tattaactga
    29641 ttctaacaca ttagtgatat gcaataatgg agtcaatgcc gatatactca tacaaggttc
    29701 aatatcctcc tcaattctca atacctttag aaagatatcc ttatattttt caaataattc
    29761 agctatatct cctatagtcc tcaaatccaa ttttttcgcc ctctgaatca tagtagatag
    29821 aaaagaacta tcaatattaa aatctatatc catatctgat gatttaatcg tattcaatag
    29881 ttcaatgtaa ttttgatctt cttttacata agtcataagc gtgctgctat ctatcggtaa
    29941 ttcttttttc gaagtaggta atttcttctt tatctcctgc tcatagttat taatattatt
    30001 tttcaactga acaaaatcat catcagccaa ttcaattagt cccgccaatc tggcaaattg
    30061 tctcctgtat tgatcaggta tatcttcctt acttttatat cccaaatcat gttcaatttc
    30121 agcccaggca tgttgcataa ctgtcctaat ttgtatctct aattttatat tcttaaatct
    30181 accatataaa gtaggtgaag tgttctcttc ttttaaaccc accacataat gaagtgaaac
    30241 ataaccaaat tttgttggat cctcactttt acgtttatca atagtattct ctacatcaac
    30301 ctcgaattct tgactgatta actcagctat tttatcaaca tcatcactaa agtacgtgat
    30361 gatacgaata ccgcataaat cggtaatctc agctaaatta gaataatttt tcctttttac
    30421 tttgccttca agagactcta cagtttttac tctcccaatt atttcatgaa cgttaataga
    30481 ttgactttta ataatattct ttacagtatt ctctacataa tttaagcaat cttcataact
    30541 cccccgtgaa gcagaatatt cttcaacaat ctccttatga ctttgagtcc tcattaatac
    30601 ctcccaaaaa gtgaacaaaa actgtctctc tttttaatta actataattt acaattattt
    30661 cacaacgata ttaacgagtt tatttggtac actaatcact ttcacgattt ccttaccgtc
    30721 aatttccgct ttgacttttt catcagcgag agcaatttct tgtaattctt cgcgtgatag
    30781 gtctttagct accatgagtt tggcacgaac ttttcctttg atttggacaa cgatttcgat
    30841 ttcgtcttca accaatttac tttcgtccca tgttggccaa gccacgtaag agattgagtc
    30901 acctgttgct gcaacagttt gccagagttc ttctgccaag tgaggtgcaa atggggcgat
    30961 catttggata aagcctttag cgtagtctac ataaagtttt tcttccttgt tagccgcgtt
    31021 gacaaagacc ataagttggg caatggcagt gttgaatttg agggattcga tttgctcagt
    31081 aacagcttta accgtttcat tataaacctt gtcgagagcg ccattgtttt ctgcaacaat
    31141 ttccttgctt gtaatcaaac ggtaaacacg gtcaaggaat ttacggcttc cttccagacc
    31201 ttcttctgac caagcaatcg aagtatcaag tggtcccatg aacatttcat agacacgaag
    31261 ggtatcagca ccgtattgtt ccaccacatc gtctgggtta accacgttct tgagggattt
    31321 agacatcttg gctggcgctt gttccaattc ttctcctgtt tccacatgga agaaagaacc
    31381 atcacgtttt tcaaccttat cagttgccac aagagcacca cggtggtcac ggtagctggt
    31441 tcccaaaatc attccttggt taaagagttt ttggaaaggt tctttagtcg gaacaacacc
    31501 gaggtcatag aggaatttgt gccagaaacg agcgtaaagc aagtgaagaa cggcatgctc
    31561 tgctccaccc acgtagatat ccactggcaa ccattgttta aggagatcct catcagccaa
    31621 tttctcagta ttgtgtggat caatatagcg gaggtagtac cagcttgaac ctgcccattg
    31681 tggcatagtg ttggtttcac gacgaccttt gacaccatct tcacgagtca cttcaagcca
    31741 gtctgtcaag ttagctagtg gactttcacc agtacctgag ggacggatgt ccttggttac
    31801 aggcaaaaca agtggcaatt cagtttcagg aacagctgtt gaagtttcat cttcccaatg
    31861 aatgatagga attggctcac cccagtaacg ttgacggcta aagagccagt cgcggagacg
    31921 gtaggtaacc ttctcttgtc cacagccttt ttcttccaac caagccacaa tcttggcaat
    31981 agcgtcttct ttgttgagtc catctaggaa gtctgaattg acatgaagac catcctctgt
    32041 gtaggcagct tctgctacat ttccaccttc aagtacttct acgattggaa ggtcaaattg
    32101 tttggcaaat tcccagtcac gttggtcatg ggcaggtaca gccataacgg cacctgtacc
    32161 atagctagca agaacgtaat ccgcaatcca gattggaatt tccttaccat tgacaggatt
    32221 gatggcataa gcaccagtcc aaacccctgt tttttctttg gcaaggtctg tacgagccaa
    32281 gtctgatttc agactggctt ggtgtttgta gtctgctact gcttctgctt gctctgtgct
    32341 tgtgattgca tctactagtt catgctcagg agccaaaacg gtgaaagtcg caccgaaaag
    32401 agtatcagga cgagtggtaa agacggtgaa ttccttgtct gttcccttaa ctttaaaagt
    32461 tacattagca ccagttgatt taccaatcca gttgcgttgc atgtccttga tagactctgg
    32521 ccagtcaagc tcgtctaagt cattgagcaa gcgctccgca taggccgtaa ttttaagcat
    32581 ccattgacgc atcggcttac ggacaactgg atagcctcca cgctcagaag ttccatcagg
    32641 aagcacttct tcattggcaa tggctgttcc caactcttcc acccagttta ctggcacttc
    32701 cgcttcatag gccaagcctt tttcgtaaag cttagtgaaa atccactgag tccacttgta
    32761 gtagtttgga tctgttgtgt tgacttcacg atcccagtca taagaaaatc caagcgcatt
    32821 gatttggcgt ttgaagttgg caatattttc cgctgtaaat tctgctgggt cattacctgt
    32881 atccatagcg tattgctctg caggcaaacc aaaagcatcc caccccattg ggtgaagaac
    32941 attgtagcct tgcgcacgtt tgtaacggct gaggatatcg gttgcggtat aaccttctgg
    33001 gtgtcctacg tgcagacccg ctccagacgg ataagggaac atatcaagcg cataaaactt
    33061 cggttttgat gcatctgttc ctgtcttaaa ggtatgatgt tctgcccagt agccctgcca
    33121 cttaggctca atttctttat gattgtaaaa actcatggtc tctctccaat tttgtgatgt
    33181 tactattata ccatttttga gggaatttga aatgtgttta aagaaaaaac tgtatactgt
    33241 atctcattaa ttttgatgac tatgaattgc tctatctccc actttttatc ccattgttat
    33301 gcagtaaatc aaggagtaag tcaagaaact tatctcgtat agcacaaaat acttatttta
    33361 gaccgaagat aaaactggaa tgctaattaa tgtattcaca ataaatagcc gacaacctat
    33421 gtcgcttttt gatttatgaa gaacgtatag t
//
LOCUS       DBEJAU010000019        32970 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC323 isolate 683620
            SAMN38261939-rid24807223.denovo.019, whole genome shotgun sequence.
ACCESSION   DBEJAU010000019 DBEJAU010000000
VERSION     DBEJAU010000019.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261939
            Sequence Read Archive: SRR26833919
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 32970)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 32970)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576303.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576303.1
            Genome Coverage       :: 154x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/19/2025 01:05:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,121
            CDSs (total)                      :: 2,078
            Genes (coding)                    :: 1,943
            CDSs (with protein)               :: 1,943
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 36
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 72 of 135
            Pseudo Genes (incomplete)         :: 63 of 135
            Pseudo Genes (internal stop)      :: 51 of 135
            Pseudo Genes (multiple problems)  :: 46 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..32970
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261939-rid24807223.denovo.019"
                     /strain="GPSC323"
                     /isolate="683620"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            165..953
                     /gene="codY"
                     /locus_tag="ACL29Z_000939"
     CDS             165..953
                     /gene="codY"
                     /locus_tag="ACL29Z_000939"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_process: GO:0045892 - negative regulation of
                     DNA-templated transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GTP-sensing pleiotropic transcriptional
                     regulator CodY"
                     /protein_id="HGR0069270.1"
                     /translation="MAHLLEKTRKITSILKRSEEQLQDELPYNAITRQLADIIHCNAC
                     IINSKGRLLGYFMRYKTNTDRVEQFFQTKIFPDDYVQGANMIYETEANLPVEHDMSIF
                     PVESRDDFPDGLTTIAPIHVSGIRLGSLIIWRNDKKFEDEDLVLVEIASTVVGIQLLN
                     FQREEDEKNIRRRTAVTMAVNTLSYSELRAVSAILGELNGNEGKLTASVIADRIGITR
                     SVIVNALRKLESAGIIESRSLGMKGTYLKVLISDIFEEVKKRDY"
     gene            953..1528
                     /locus_tag="ACL29Z_000940"
     CDS             953..1528
                     /locus_tag="ACL29Z_000940"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255720.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase family protein"
                     /protein_id="HGR0069271.1"
                     /translation="MTKALISIDYTEDFVADSGKLTAGAPAQAISDAISKVTRLAFER
                     GDYIFFTIDAHEENDCFHLESKLFPPHNLIGTSGRNLYGDLGIFYQEHGSDSRVFWMD
                     KRHYSAFSGTDLDIRLRERRVSTVILTGVLTDICVLHTAIDAYNLGYDIEIVKPAVAS
                     IWPENHQFALGHFKNTLGAKLVDENLNELSE"
     gene            1610..1695
                     /locus_tag="ACL29Z_000941"
     tRNA            1610..1695
                     /locus_tag="ACL29Z_000941"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1644..1646,aa:Leu,seq:aag)
     gene            1978..3108
                     /locus_tag="ACL29Z_000942"
     CDS             1978..3108
                     /locus_tag="ACL29Z_000942"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003010064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGR0069272.1"
                     /translation="MVELNLKNIYKKYPNSEHYSVEDFNLNIKDKEFIVFVGPSGCGK
                     STTLRMIAGLEDITEGTASIDGVVVNDVAPKDRDIAMVFQNYALYPHMTVYDNMAFGL
                     KLRKYSKEDINKRVQEAAEILGLKEFLERKPADLSGGQRQRVAMGRAIVRDAKVFLMD
                     EPLSNLDAKLRVSMRAEIAKIHRRIGATTIYVTHDQTEAMTLADRIVIMSATKNPAGT
                     GTIGRVEQIGTPQEVYKNPVNKFVAGFIGSPAMNFINVKLVGSEIVSDGFRLKVPEGA
                     LKVLREKGYEGKELIFGIRPEDVNAEPAFLETFPDCVVKATISVSELLGSESHLYCQV
                     GKDEFVAKVDARDYLQTGATVELGFDLNKAHFFDVETEKTIY"
     gene            3609..4367
                     /locus_tag="ACL29Z_000943"
     CDS             3609..4367
                     /locus_tag="ACL29Z_000943"
                     /EC_number="2.1.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001848902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008168 - methyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HGR0069273.1"
                     /translation="MSEAGHKFLAKLGKKRLRPGGKRATDWLIAEGGFSKEKRILEVA
                     CNRGTTAIELAQRFGCKITAIDMDAQALEVAKKSAGTAGVAHLISFERANAMKLPYQD
                     ASFDIVINEAMLTMQADQAKKKCVMEYLRVLKPGGLLLTHDVLLKEAKESIRQELSQA
                     IHVNVGPLTQDGWEQVMIESGYCDVKALTGEMTLMKLSGMIYDEGLLGTLKICVNACK
                     KENRKQFLTMYKMFAKNKQKLGFIAMASYKSSKR"
     gene            4454..4966
                     /locus_tag="ACL29Z_000944"
     CDS             4454..4966
                     /locus_tag="ACL29Z_000944"
                     /EC_number="2.4.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001049318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003999 - adenine
                     phosphoribosyltransferase activity [Evidence IEA];
                     GO_process: GO:0006168 - adenine salvage [Evidence IEA];
                     GO_process: GO:0009116 - nucleoside metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="adenine phosphoribosyltransferase"
                     /protein_id="HGR0069274.1"
                     /translation="MNLKDYIATIENYPKEGITFRDISPLMADGNAYSYAVREIVQYA
                     TDKKVDMIVGPEARGFIVGCPVAFELGIGFAPVRKPGKLPREVISADYEKEYGVDTLT
                     MHADAIKPGQRVLIVDDLLATGGTVKATIEMIEKLGGVMAGCAFLVELDELNGREKIG
                     DYDYKVLMHY"
     gene            5148..6092
                     /gene="metA"
                     /locus_tag="ACL29Z_000945"
     CDS             5148..6092
                     /gene="metA"
                     /locus_tag="ACL29Z_000945"
                     /EC_number="2.3.1.46"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001122710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0008899 - homoserine O-succinyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0019281 - L-methionine biosynthetic process
                     from homoserine via O-succinyl-L-homoserine and
                     cystathionine [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="homoserine O-succinyltransferase"
                     /protein_id="HGR0069275.1"
                     /translation="MPIRIDKKLPAVEILRTENIFVMDDQRAAHQDIRPLKILILNLM
                     PQKMVTETQLLRHLANTPLQLDIDFLYMESHRSKTTRSEHMETFYKTFPEVKDEYFDG
                     MIITGAPVEHLPFEEVDYWEEFRQMLEWSKTHVYSTLHICWGAQAGLYLRYGVEKYQM
                     DSKLSGIYPQDTLKEGHLLFRGFDDSYVSPHSRHTEISKEEVLNKTNLEILSEGPQVG
                     VSILASRDLREIYSFGHLEYDRDTLAKEYFRDRDAGFDPHIPENYFKDDDVNQVPCLC
                     WSSSAALFFSNWINHAVYQETPFDWRKIEDDASAYGYL"
     gene            6101..6778
                     /locus_tag="ACL29Z_000946"
     CDS             6101..6778
                     /locus_tag="ACL29Z_000946"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006269 - DNA replication, synthesis of
                     primer [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DnaD domain protein"
                     /protein_id="HGR0069276.1"
                     /translation="MTYLDAFKSGILVLPSALLLHFKELFPSSDDFLVWQFFYLQNTT
                     GLEEMSPSQIAERIGKEISDVNQSISNLTERGLLQYRTIELNGEIELLFDASLALERL
                     DDLFGAVHSSSDQLTPQNQLKDLVETFQQELGRLLTPFEIEDLTKTLKEDGTSADLIK
                     EALREAVLNGKPNWKYIQAILRNWRHEGIKSVAQIEAKRAEREASNPQLTQVSADFRN
                     AMDLWKD"
     gene            6877..7635
                     /gene="tpiA"
                     /locus_tag="ACL29Z_000947"
     CDS             6877..7635
                     /gene="tpiA"
                     /locus_tag="ACL29Z_000947"
                     /EC_number="5.3.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000087908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004807 - triose-phosphate isomerase
                     activity [Evidence IEA];
                     GO_process: GO:0006096 - glycolytic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="triose-phosphate isomerase"
                     /protein_id="HGR0069277.1"
                     /translation="MSRKPFIAGNWKMNKNPEEAKAFVEAVASKLPSSDLVEAGIAAP
                     ALDLTTVLAVAKGSNLKVAAQNCYFENAGAFTGETSPQVLKEIGTDYVVIGHSERRDY
                     FHETDEDINKKAKAIFANGMLPIICCGESLETYEAGKATEFVGAQVSAALAGLTAEQV
                     AASVIAYEPIWAIGTGKSASQDDAQKMCKVVRDVVAADFGQEVADKVRVQYGGSVKPE
                     NVASYMACPDVDGALVGGASLEAESFLALLDFVK"
     gene            7673..9178
                     /gene="lytC"
                     /locus_tag="ACL29Z_000948"
     CDS             7673..9178
                     /gene="lytC"
                     /locus_tag="ACL29Z_000948"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_078138769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline binding-anchored murein hydrolase LytC"
                     /protein_id="HGR0069278.1"
                     /translation="MSVTFFIGEERLKIKIGLASICLLGLATSHVAANETEVAKTSQD
                     TTTASSSSEQNQSSNKTQTSAEVQTNAAAHWDGDYYVKDDGSKAQSEWIFDNYYKAWF
                     YINSDGRYSQNEWHGNYYLKSGGYMAQNEWIYDSNYKSWFYLKSDGAYAHQEWQLIGN
                     KWYYFKKWGYMAKSQWQGSYFLNGQGAMMQNEWLYDPAYSAYFYLKSDGTYANQEWQK
                     VGGKWYYFKKWGYMARNEWQGNYYLTGSGAMATDEVIMDGARYIFAASGELKEKKDLN
                     VGWVHRDGKRYFFNNREEQVGTEHAKKIIDISEHNGRINDWKKVIDENEVDGVIVRLG
                     YSGKEDKELAHNIKELNRLGIPYGVYLYTYAENETDAENDAKQTIELIKKYNMNLSYP
                     IYYDVENWEYVNKSKRAPSDTDTWVKIINKYMDTMKQAGYQNVYVYSYRSLLQTRLKH
                     PDILKHVNWVAAYTNALEWENPYYSGEKGWQYTSSEYMKGIQGRVDVSVWY"
     gene            9675..10193
                     /locus_tag="ACL29Z_000949"
     CDS             9675..10193
                     /locus_tag="ACL29Z_000949"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000229877.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA starvation/stationary phase protection
                     protein"
                     /protein_id="HGR0069279.1"
                     /translation="MVELKKEAVKDVTSLTKAAPVALAKTKEVLNQAVADLYVAHVAL
                     HQVHWYMHGRGFLVWHPKMDEYMEALDGQLDEISERLITLGGSPFSTLTEFLQNSEIE
                     EEAGEYRNVEESLERVLVIYRYLSELFQKGLDVTDEEGDDVTNGIFAGAKTETDKTIW
                     MLAAELGQAPGL"
     gene            10323..10829
                     /locus_tag="ACL29Z_000950"
     CDS             10323..10829
                     /locus_tag="ACL29Z_000950"
                     /EC_number="1.5.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000162460.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004146 - dihydrofolate reductase activity
                     [Evidence IEA];
                     GO_function: GO:0050661 - NADP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrofolate reductase"
                     /protein_id="HGR0069280.1"
                     /translation="MTKKIVAIWAQDEEGVIGKKNRLPWHLPAELQHFKETTLNHAIL
                     MGRVTFDGMGRRLLPKRETLILTRNPEEKIDGVATFQDVQSVLDWYQAQEKNLYIIGG
                     KQIFQAFEPYLDEVIVTHIHARVEGDTYFPEELDLSLFETVSSKFYAKDEKNPYDFTI
                     QYRKRKEV"
     gene            11031..12263
                     /gene="clpX"
                     /locus_tag="ACL29Z_000951"
     CDS             11031..12263
                     /gene="clpX"
                     /locus_tag="ACL29Z_000951"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002874765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0046983 - protein dimerization activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit
                     ClpX"
                     /protein_id="HGR0069281.1"
                     /translation="MSTNRKNDMMVYCSFCGKNQEEVQKIIAGNNAFICNECVELAQE
                     IIREELVEEVLADLSEVPKPIELLHILNHYVIGQDRAKRALAVAVYNHYKRINFHDTR
                     EESEDVDLQKSNILMIGPTGSGKTFLAQTLAKSLNVPFAIADATALTEAGYVGEDVEN
                     ILLKLLQVADFNIERAERGIIYVDEIDKIAKKSENVSITRDVSGEGVQQALLKIIEGT
                     VASVPPQGGRKHPQQEMIQVDTKNILFIVGGAFDGIEEIVKQRLGEKVIGFGQNNKAI
                     DANSSYMQEIIAEDIQKFGIIPELIGRLPVFAALEQLTVDDLVRILKEPRNALVKQYQ
                     TLLSYDDVELEFDDEALQEIANKAIERKTGARGLRSIIEETMLDVMFEVPSQENVKLV
                     RITKETVDGTDKPILETA"
     gene            12272..12859
                     /gene="yihA"
                     /locus_tag="ACL29Z_000952"
     CDS             12272..12859
                     /gene="yihA"
                     /locus_tag="ACL29Z_000952"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002915299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_function: GO:0043022 - ribosome binding [Evidence IEA];
                     GO_process: GO:0042254 - ribosome biogenesis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTP-binding protein
                     YihA/YsxC"
                     /protein_id="HGR0069282.1"
                     /translation="MELNTHNAEILLSAANKSHYPQDELPEIALAGRSNVGKSSFINT
                     MLNRKNLARTSGKPGKTQLLNFFNIDDKMRFVDVPGYGYARVSKKEREKWGCMIEEYL
                     TTRENLRAVVSLVDLRHDPSADDVQMYEFLKYYEIPVIIVATKADKIPRGKWNKHESA
                     IKKKLNFDPSDDFILFSSVSKAGMDEAWDAILEKL"
     gene            12870..13250
                     /locus_tag="ACL29Z_000953"
     CDS             12870..13250
                     /locus_tag="ACL29Z_000953"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001140413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RidA family protein"
                     /protein_id="HGR0069283.1"
                     /translation="MAKTIHTDKAPKAIGPYVQGKIVGNLLFASGQVPLSPETGEIVG
                     ENIQEQTEQVLKNIGAILAEAGTDFDHVVKTTCFLSDMNDFVPFNEVYQTAFKEEFPA
                     RSAVEVARLPRDVKVEIEVIAEIG"
     gene            13302..14192
                     /gene="rapZ"
                     /locus_tag="ACL29Z_000954"
     CDS             13302..14192
                     /gene="rapZ"
                     /locus_tag="ACL29Z_000954"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000163059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RNase adapter RapZ"
                     /protein_id="HGR0069284.1"
                     /translation="MTKKQLHLVIVTGMSGAGKTVAIQSFEDLGYFTIDNMPPALLPK
                     FLQLVEIKEDNPKLALVVDMRSRSFFSEIQAVLDELENQDGLDFKILFLDAADKELVA
                     RYKETRRSHPLAADGRILDGIKLERELLAPLKNMSQNVVDTTELTPRELRKTLAEQFS
                     DQEQAQSFRIEVMSFGFKYGIPIDADLVFDVRFLPNPYYLPELRNKTGVDEPVYDYVM
                     NHPESEDFYQHLLALIEPILPSYQKEGKSVLTIAMGCTGGQHRSVAFAKRLAQDLSKN
                     WSVNEGHRDKDRRKETVNRS"
     gene            14189..15166
                     /locus_tag="ACL29Z_000955"
     CDS             14189..15166
                     /locus_tag="ACL29Z_000955"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YvcK family protein"
                     /protein_id="HGR0069285.1"
                     /translation="MRKPKITVIGGGTGIPVILKSLREKDVEIAAIVTVADDGGSSGE
                     LRKNMQQLTPPGDLRNVLVAMSDMPKFYEKVFQYRFSEDAGAFAGHPLGNLIIAGLSE
                     MQGSTYNAMQLLSKFFHTTGKIYPSSDHPLTLHAVFQDGTEVAGESHIVDHRGIIDNV
                     YVTNALNDDTPLASRRVVQTILESDMIVLGPGSLFTSILPNIVIKEIGRALLETKAEI
                     AYVCNIMTQRGETEHFTDSDHVEVLHRHLGRPFIDTVLVNIEKVPQEYMNSNRFDEYL
                     VQVEYDFVGLCKQVSRVISSNFLRLENGGAFHDGDLIVDELMRIIQVKK"
     gene            15163..16074
                     /gene="whiA"
                     /locus_tag="ACL29Z_000956"
     CDS             15163..16074
                     /gene="whiA"
                     /locus_tag="ACL29Z_000956"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004257845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0043937 - regulation of sporulation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein WhiA"
                     /protein_id="HGR0069286.1"
                     /translation="MSFTVAVKEEILGQHHLSWYELSAIIKMSGSIGLSTSGLTLSVV
                     TENAKLARHLYESFLHFYEIKSEIRHHQRSNLRKNRVYTVFTDEKVQDLLSDLHLADS
                     FFGLETGIDEAILSDEEAGRAYLCGAFLANGSIRDPESGKYQLEISSVYLDHAQGIAS
                     LLQQFLLDAKVLERKKGAVTYLQRAEDIMDFLIVIGAMQARDDFERVKILRETRNDLN
                     RANNAETANIARTVSASMKTINNISKIKDIMGLENLPVDLQEVAQLRIQHPDYSIQQL
                     ADSLSTPLTKSGVNHRLRKINKIADEL"
     gene            complement(16108..17076)
                     /locus_tag="ACL29Z_000957"
     CDS             complement(16108..17076)
                     /locus_tag="ACL29Z_000957"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000081018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA];
                     GO_function: GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HGR0069287.1"
                     /translation="MSQLYDITIVGGGPVGLFAAFYAHLRQAKVQIIDSLPQLGGQPA
                     ILYPEKEILDVPGFPNLTGEELTNRLIEQLNGFDTPIHLNETVLEIDKQEEEFAITTS
                     KGSHLTKTVIIAMGGGAFKPRPLELEGVEGYENIHYHVSNIQQYAGKKVTILGGGDSA
                     VDWALAFEKIAPTTLVHRRDNFRALEHSVQALQESSVTIKTPFAPSQLLGNGKTLDKL
                     EITKVKSDETETIDLDHLFVNYGFKSSVGNLKNWGLDLNRHKIIVNSKQESSQAGIYA
                     IGDCCYYDGKIDLIATGLGEAPTAVNNAINYIDPEQKVQPKHSTSL"
     gene            17212..18069
                     /gene="cdaA"
                     /locus_tag="ACL29Z_000958"
     CDS             17212..18069
                     /gene="cdaA"
                     /locus_tag="ACL29Z_000958"
                     /EC_number="2.7.7.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001867651.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004016 - adenylate cyclase activity
                     [Evidence IEA];
                     GO_process: GO:0006171 - cAMP biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="diadenylate cyclase CdaA"
                     /protein_id="HGR0069288.1"
                     /translation="MNFQQLSNLQYWTSLFASPWTIAINLIDILIVAYILYHFTKAIA
                     GTKIMILVRGVLVFILAQILANMIGLTTISWLINQIITYGVIAAVVIFSPEIRTGLER
                     LGRATDFFSNAPISAEEQMIRAFVKSVEYMSPRKIGALVAIQRVRTLQEYTSTGIPLD
                     AKISAELLINIFIPNTPLHDGAVIIKEERIAVTSAYLPLTKNTGISKEFGTRHRAAIG
                     LSEVSDALTFVVSEETGGISITYNGRFKHNLTLDEFETELREILLPKEEVGLSFKERL
                     LGGWKHEKK"
     gene            18056..18835
                     /locus_tag="ACL29Z_000959"
     CDS             18056..18835
                     /locus_tag="ACL29Z_000959"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397683.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CdaR family protein"
                     /protein_id="HGR0069289.1"
                     /translation="MKKNSLYIISSLFFACVLFVYATATNFQNSTSARQVKTETYTNT
                     VTNVPIDIRYNSDKYFISGFASEVSVVLTGANRLSLASEMQESTRKFKVTADLTDAGV
                     GTIEVPLSIEDLPNGLTAVATPQKITVKIGKKAQKDKVKIVPEIDPSQIDSRVQIENV
                     MVSDKEVSITSDQETLDRIDKIIAVLPTSERITGNYSGSVPLQAIDRNGVVLPAVITP
                     FDTIMKVTTKPVAPSSSTSNSSTSSSSETSSSTKATSSKTN"
     gene            18859..20211
                     /gene="glmM"
                     /locus_tag="ACL29Z_000960"
     CDS             18859..20211
                     /gene="glmM"
                     /locus_tag="ACL29Z_000960"
                     /EC_number="5.4.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000287 - magnesium ion binding [Evidence
                     IEA];
                     GO_function: GO:0008966 - phosphoglucosamine mutase
                     activity [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglucosamine mutase"
                     /protein_id="HGR0069290.1"
                     /translation="MGKYFGTDGVRGEANLELTPELAFKLGRFGGYVLSQHETEAPKV
                     FVGRDTRISGEMLESALVAGLLSVGIHVYKLGVLATPAVAYLVETEGASAGVMISASH
                     NPALDNGIKFFGGDGFKLDDEKEAEIEALLDAEEDTLPRPSAEGLGILVDYPEGLRKY
                     EGYLVSTGTPLDGMKVALDTANGAASTSARQIFADLGAQLTVIGETPDGLNINLNVGS
                     THPEALQEVVKESGSAIGLAFDGDSDRLIAVDENGDIVDGDKIMYIIGKYLSEKGQLA
                     QNTIVTTVMSNLGFHKALNREGINKAVTAVGDRYVVEEMRKSGYNLGGEQSGHVILMD
                     YNTTGDGQLSAVQLTKIMKETGKSLSELAAEVTIYPQKLVNIRVENVMKEKAMEVPAI
                     KAIIEKMEEEMAGNGRILVRPSGTEPLLRVMAEAPTTEEVDYYVDTITDVVRAEIGID
                     "
     gene            20285..20659
                     /locus_tag="ACL29Z_000961"
     CDS             20285..20659
                     /locus_tag="ACL29Z_000961"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001050081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1149 family protein"
                     /protein_id="HGR0069291.1"
                     /translation="MNLKREQEFVSQYHFDARNFEWENENGAPETKVDVNFQLLQHDQ
                     ENQVTSLIVILSFMIVFDKFVISGTISQVNHIDGRIVNEPSELNQEEVETLARPCLNM
                     LNRLTYEVTEIALDLPGINLEF"
     gene            20661..21509
                     /locus_tag="ACL29Z_000962"
     CDS             20661..21509
                     /locus_tag="ACL29Z_000962"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000762171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005504 - fatty acid binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HGR0069292.1"
                     /translation="MKLAVFTDSSAYLSEETLQREDLFVLDIPVNIDGEEYVEGINLS
                     AEEFYQKMAQASELPKTSQPSIAKLDEILTSLKEQGYTHALGLFLSSGISGFYQNIQY
                     MVDDYEGLTIAFSDTLITSAPLGIMVESVFNWRDQGDDFASIQDKLAIQISRTSAFIM
                     VDDLDHLVKGGRLSNGAAILGNLLSIKPILYFNDQGVIEVYEKVRTEKKATKRLIEII
                     KETTASGQYRVIVIHGNAPEKAEELRQHLLDFGLGSDVSLATFGSVIGTHLGAGSIAL
                     GYIPVI"
     gene            21786..22553
                     /gene="dapB"
                     /locus_tag="ACL29Z_000963"
     CDS             21786..22553
                     /gene="dapB"
                     /locus_tag="ACL29Z_000963"
                     /EC_number="1.17.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002897644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008839 - 4-hydroxy-tetrahydrodipicolinate
                     reductase [Evidence IEA];
                     GO_process: GO:0009089 - lysine biosynthetic process via
                     diaminopimelate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxy-tetrahydrodipicolinate reductase"
                     /protein_id="HGR0069293.1"
                     /translation="MSIRVIIAGFKGKMGQAACQMVLTDPDLDLVAVLDSFESESEWQ
                     GIPVFKDKADLAGFEADVWVDFTTPAVAYENTRFALENGFAPVVGTTGFTSEEIAELK
                     EFSRAQDLGGLIAPNFALGAVLLMQFATQAAKYFPNVEIIELHHDKKKDAPSGTAIKT
                     AELMAEVRESIQQGAADEEELIAGARGADFDGMRIHSVRLPGLVAHQEVIFGNQGEGL
                     TLRHDSYDRISFMTGVNLGIKEVVKRHELVYGLEHLL"
     gene            22550..23749
                     /locus_tag="ACL29Z_000964"
     CDS             22550..23749
                     /locus_tag="ACL29Z_000964"
                     /EC_number="2.7.7.72"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001808398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016779 - nucleotidyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0001680 - tRNA 3'-terminal CCA addition
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="CCA tRNA nucleotidyltransferase"
                     /protein_id="HGR0069294.1"
                     /translation="MRLTQMPSEFQKALPVLEKIKEAGFEAYFVGGSVRDALLHSPIH
                     DVDIATSSYPEETKQIFPRTADIGIEHGTVLVLDGDEEYEVTTFRTEDVYVDYRRPSA
                     VSFVRSLEEDLKRRDFTVNAFALDETGEIVDLFHGLEDLEKQVLRAVGVASERFNEDA
                     LRIMRGFRFQASLGFALEPETFKAMKTLTPLLEKISVERTFVEFDKLLLAPFWRRGLA
                     SMIESQAYDYLPDMASSQDKLNRLFDLETDFTFESSEQAWAALLWALEIENAQSFLKS
                     WKTSRQFAKQVQDLLIILALRENGELSKRDCYRFDIDLLLQAENLRQAQGKEVNPQAI
                     TEKYQSLTIHDKKEIQINGDILIKEYGYQPGPDLGEILTEIEFAIVDGELENNREAIH
                     AYLREKK"
     gene            23746..25617
                     /locus_tag="ACL29Z_000965"
     CDS             23746..25617
                     /locus_tag="ACL29Z_000965"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001279112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HGR0069295.1"
                     /translation="MSDFIVEKLSKSVGDKTVFRDISFIIHDLDRIGLIGVNGTGKTT
                     LLDVLSGVSGFDGDVSPFSAKNDYQIGYLTQDPDFDDRKTVLDTVLSSELKEIQLIRE
                     YELIMLDYSEDKQARLERVMAEMDSLQAWEIESQVKTVLSKLGIQDLSTPVGELSGGL
                     RRRVQLAQVLLGNHDLLLLDEPTNHLDIAIIEWLTLFLKNSKKTVLFITHDRYFLDAL
                     STRIFELERAGLTEYQGNYQDYVRLKAEQDERDAALLHKKEQLYKQELAWMRRQPQAR
                     ATKQQARINRFHDLKKEVSGSSAETDLTMNFETSRIGKKVIEFQDVSFAYENKPILQD
                     FNLLVQAKDRIGIVGDNGVGKSTLLNLIAGSLEPTAGQVVIGETVRIAYFSQQIEGLD
                     ESKRVINYLQEVAEEVKTSGGSTTSIAELLEQFLFPRSTHGTLIEKLSGGEKKRLYLL
                     KLLLEKPNVLLLDEPTNDLDIATLTVLENFLQGFAGPVLTVSHDRYFLDKVATKILAF
                     EDGKIRPFFGHYTDYLDEKAFETDMANQVQKAEKEKVVKVREDKKRMTYQEKQEWASI
                     EGDIETLEKRIAAIEEEMQANGSDFGKLATLQKELDEKNEALLEKYERYEYLSEFDS"
     gene            complement(25760..26944)
                     /gene="mntE"
                     /locus_tag="ACL29Z_000966"
     CDS             complement(25760..26944)
                     /gene="mntE"
                     /locus_tag="ACL29Z_000966"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000813920.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CDF family manganese efflux transporter MntE"
                     /protein_id="HGR0069296.1"
                     /translation="MKQSISNLKLAERGAIISISTYLILSAAKLAAGHLLHSSSLVAD
                     GFNNVSDIIGNVALLIGIRMARQPADRDHRFGHWKIEDLASLITSIIMFYVGFDVLRD
                     TIQKILSREETVIDPLGATLGIISAAIMFVVYLYNTRLSKKSNSKALKAAAKDNLSDA
                     VTSLGTAIAILASSFNYPIVDKLVAIIITFFILKTAYDIFIESSFSLSDGFDDRLLED
                     YQKAIMEIPKISKVKSQRGRTYGSNIYLDITLEMNPDLSVFESHEIADQVESMLEERF
                     GVFDTDVHIEPAPIPEDEILDNVYKKLLMREQLIDQGNQLEELLTDDFVYIRQDGEQM
                     DKEAYKTKKELNSAIKDIQITSISQKTKLICYELDGIIHTSIWRRHETWQNIFHQETK
                     KE"
     gene            27248..29944
                     /locus_tag="ACL29Z_000967"
     CDS             27248..29944
                     /locus_tag="ACL29Z_000967"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000032417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation-translocating P-type ATPase"
                     /protein_id="HGR0069297.1"
                     /translation="MSKEQKRQAFYTQSPEEVLQAVDATEQGLSSSEAEKRLAEFGHN
                     ELEEGEKRSILVKFIEQFKDLMIIILVAAAILSVVTSGGEDIADAIIILAVVIINAAF
                     GVYQEGKAEEAIEALKSMSSPVARVLRDGHMAEIDSKELVPGDIVALEAGDVVPADLR
                     LIEANSLKIEEAALTGESVPVEKDLSVEFATDAGIGDRVNMAFQNSNVTYGRGMGVVV
                     NTGMYTEVGHIAGMLQDADETDTPLKQNLNNLSKVLTYAILVIALVTFVVGVFIQGKN
                     PLGELLTSVALAVAAIPEGLPAIVTIVLSLGTQVLAKRHSIVRKLPAVETLGSTEIIA
                     SDKTGTLTMNKMTVEKVFYDAVLHDSADDIELGLEMPLLRSVVLANDTKIDVEGNLIG
                     DPTETAFIQYALDKGYDVKGFLEKYPRVAELPFDSDRKLMSTVHPLPDGRFLVAVKGA
                     PDQLLKRCLLRDKAGDIAPIDEKVTNLIHTNNSEMAHQALRVLAGAYKIIDSIPENLT
                     SEELENDLIFTGLIGMIDPERPEAAEAVRVAKEAGIRPIMITGDHQDTAEAIAKRLGI
                     IDANDTEGHVLTGAELNELSDEEFEKVVGQYSVYARVSPEHKVRIVKAWQKQGKVVAM
                     TGDGVNDAPALKTADIGIGMGITGTEVSKGASDMILADDNFATIIVAVEEGRKVFSNI
                     QKTIQYLLSANTAEVLTIFLSTLFGWDVLQPVHLLWINLVTDTFPAIALGVEPAEPGV
                     MNHKPRGRKASFFSGGVLSSIIYQGVLQAALVMSVYGLAIAYPVHVGDNHAIHADALT
                     MAFATLGLIQLFHAYNVKSVYQSILTVGPFKSKTFNWSILVSFILLMATIVVEPLEGI
                     FHVTKLDLSQWGIVMAGSFSMIIIVEIVKFIQRKLGFDKNAI"
     gene            29957..30748
                     /gene="yghU"
                     /locus_tag="ACL29Z_000968"
     CDS             29957..30748
                     /gene="yghU"
                     /locus_tag="ACL29Z_000968"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001277405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005515 - protein binding [Evidence IEA];
                     GO_process: GO:0006749 - glutathione metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione-dependent disulfide-bond
                     oxidoreductase"
                     /protein_id="HGR0069298.1"
                     /translation="MSAYQLPTVWQDEASNQGAFTGLNRPTAGARFEQNLPKGEQAFQ
                     LYSLGTPNGVKVTILLEELLEAGFKEAAYDLYKIAIMDGDQFGSDFVKLNPNSKIPAL
                     LDQSGTENVRVFESAHILLYLAEKFGAFLPSNPVEKIEVLNWLFWQAGAAPFLGGGFG
                     HFFNYAPEKLEYPINRFTMEVKRQLDLLDKELAQKPYIAGNDYTIADIAIWSWYGQLV
                     QGNLYQGSAKFLDASSYQNLVKWAEKIANRPAVKRGLEVTYTEIK"
     gene            30864..31274
                     /locus_tag="ACL29Z_000969"
     CDS             30864..31274
                     /locus_tag="ACL29Z_000969"
                     /EC_number="3.5.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000412213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide deformylase"
                     /protein_id="HGR0069299.1"
                     /translation="MEKKIVKDNLFLSQVSQPASQEDLYLARDLQDTLLANRDTCVGL
                     AANMIGVQKRVIIFNLGLVPVVMFNPVLLSFEGSYEAEEGCLSLVGVRSTKRYETIRL
                     AYRDSKWQEQTITLTGFPAQICQHELDHLEGRII"
     gene            31286..32881
                     /locus_tag="ACL29Z_000970"
     CDS             31286..32881
                     /locus_tag="ACL29Z_000970"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000822862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0069300.1"
                     /translation="MKRIVFELIFIATTWYIFLPPLNLTSWEFLFFLCGHLLVVAILF
                     GFGKGINLVKTVHVRHGKAEAALNLEGFKINRLGKILLASIGGILLLAALVSLVTSSM
                     FQAKNYANVVTVTEKDFTEFPKSDTSKVPILDRSTAEKIGDRYLGSLTDKVSQYVAAD
                     TYTQLTIDGKPYRVTPLEYADPIKWFNNQAKGIGEYIKVDMVTGNADLVDLKTPIKYS
                     DSEYFNRDVKRHLRLKYPTKIFKTPSFEVDDEGNPFYVATVYQKQFGLAVPRPASVII
                     LDATNGETKEYSLSDVPEWVDRIYPAEETIEQINYNGKYKDGFLNAMISKKNVTQTTN
                     GYNYLSIGNDIYLYTGVTSANADESNLGFILENMRTGEITKYSLASATEESARESAEG
                     AVQEKSYKATFPILINLNDKPLYIMGLKDNAGLVKEYALVDAVEYQNVIVATTVEEML
                     SKYANKNDLEIDNATTESIKGVVADLKSAVIKGDTVYFFKVDGKIYKVKASVSDDLPY
                     LENGKTFEGQVGKDNYLKTFKVQ"
BASE COUNT         9725 a         6131 c         7590 g         9524 t
ORIGIN      
        1 caaaaatagg caacttgtca atagaaaagg aacaatttaa ttaaaaatat tctggttttt
       61 aattaaattg taagtcaatg caagtcaata aggaattttc agataattat tgaaaaagag
      121 acgtttttat gttataatga tagcgattaa attcgaggtg aaaaatggca catttattag
      181 aaaaaactag aaaaattaca tcaattttga aacgctcaga ggagcagttg caggatgagc
      241 tcccttacaa cgctattacg cgtcagttag cggatattat tcattgcaat gcctgcatta
      301 tcaatagtaa gggacgtctg cttggctatt ttatgcgtta taaaacaaat acagatcgcg
      361 tagagcaatt cttccaaact aagattttcc cagatgacta cgttcaaggg gctaatatga
      421 tttacgaaac agaagcaaac ttgcctgttg agcatgatat gagtattttc cctgttgaga
      481 gtagagatga ttttccagat ggcttgacga ctattgcacc gattcatgta tcggggattc
      541 gccttggttc tttgattatt tggcgtaatg ataaaaaatt cgaagatgag gacttggttc
      601 ttgttgagat tgccagtacc gttgttggga ttcagcttct taacttccaa cgtgaagaag
      661 atgagaaaaa tattcgtcgt cgtactgctg tcaccatggc ggtcaatacc ctttcttact
      721 ccgaactccg tgctgtttca gcaattttag gggaattaaa tggaaatgaa gggaagttga
      781 ctgcgtcagt gattgcagat cgtatcggaa tcactcgctc tgtgattgtc aatgctcttc
      841 gtaaacttga gtctgcgggg attattgaaa gtcgctcact tggaatgaag ggaacctatc
      901 ttaaggtctt gatttcagat atttttgaag aagtgaagaa aagagattac taatgacaaa
      961 ggctttaatt tcgattgatt atacagaaga ttttgttgct gatagtggga aactaacagc
     1021 aggtgctcca gctcaggcga tttcggatgc catcagcaag gtaactcgat tagcttttga
     1081 acgaggagat tatatcttct ttactattga tgctcatgaa gaaaacgatt gtttccatct
     1141 ggaaagtaag ttatttcctc ctcataatct gattgggacg agtggacgga atttatatgg
     1201 agatttgggg atcttttatc aagagcatgg ttcagacagt cgtgtctttt ggatggataa
     1261 acgccattac tcagcttttt cagggactga cctagatatt cgtttgagag agcgtagagt
     1321 gtctaccgtt atcttaacag gtgtcttgac ggatatctgt gtcctacata cagctataga
     1381 tgcctataat ctaggatatg acatcgagat tgttaaacca gctgttgctt ccatctggcc
     1441 tgaaaatcat caatttgccc taggtcattt caaaaataca ctcggagcta agttagtaga
     1501 tgaaaatcta aatgaacttt ctgagtaacc tggttggtga aaatgaaaaa atttgaaaaa
     1561 aagtgttgac aagcatccca aaagttgata tactagtaaa gtaatcgatg cggggatggc
     1621 ggaattggca gacgcgcagg actaaggatc ctgtgaccgc tttaggtcgt gagggttcaa
     1681 gtccctctct ccgcatagga aaagagctag ctaaagctag ctcttttgta tttctctaaa
     1741 aaattagaat ccagtcaaat gtagtggaga atcagcgaaa atatgggaaa actgatcctt
     1801 gtttctgctt ttgtcataga agaataataa agattatctt cttcaaattc tccgatattc
     1861 tctaaagttt tgtgcaagtt gcacagaact tttttatttt tttggtcatc ttgccataga
     1921 aatataaagc gttttcatct ataatataat tatcaaaaga caaaaggagt tcacctcatg
     1981 gtagaattga atcttaaaaa tatttacaaa aaatatccaa acagcgaaca ctattcagtt
     2041 gaagatttca acttgaacat caaagataaa gaatttatcg ttttcgtagg accttcagga
     2101 tgtggtaaat caactacact ccgtatgatt gctggtcttg aagacattac agaaggtact
     2161 gcatctatcg atggcgtggt tgtcaacgac gtagctccaa aagaccgtga tatcgccatg
     2221 gtattccaaa actacgctct ttacccacac atgactgttt atgacaacat ggctttcggt
     2281 ttgaaattgc gtaaatacag caaagaagac attaacaaac gtgttcaaga agcagctgaa
     2341 atacttggat tgaaagaatt cttggaacgt aaaccagctg acctttcagg tggtcaacgt
     2401 caacgtgttg ccatggggcg tgcgattgtc cgtgatgcga aagtattctt gatggacgaa
     2461 cctttgtcaa acttggatgc caaacttcgt gtatcaatgc gtgctgaaat cgctaaaatt
     2521 caccgtcgta tcggagctac aactatctat gtaactcacg accaaacaga agcgatgaca
     2581 cttgcagacc gtatcgttat tatgtcagct actaagaacc ctgctggtac aggtactatc
     2641 ggacgtgtag aacaaatcgg tactcctcaa gaagtttaca aaaatccagt taacaaattc
     2701 gttgcaggat tcatcggaag cccagctatg aacttcatca acgtgaaatt ggttggtagc
     2761 gaaattgttt ctgacggttt ccgtttgaaa gtgccagaag gagcattgaa agttcttcgt
     2821 gaaaaaggct acgaaggaaa agaattgatc tttggtatcc gtccagaaga cgtgaatgca
     2881 gaacctgctt tccttgaaac attcccagac tgtgttgtaa aagcgactat ctctgtatca
     2941 gaactgcttg gttcagaatc tcacctttac tgccaagttg gtaaagacga gtttgttgca
     3001 aaagttgatg ctcgtgacta cttgcaaaca ggtgcaacag ttgagcttgg atttgacttg
     3061 aacaaagcac acttcttcga tgtagaaact gaaaaaacaa tctactaaaa taaataaaat
     3121 tcaaagcact acaagaaaag atatctcttt atcaattgta gtggagagat atcagttaat
     3181 ctagggagag aaacaaaatg cttctctcct ttttgctagg gaagtcatat tatgcatcta
     3241 tattgtgatg ctctttaata ctcttcgaaa atctcttcaa accacgtcaa cgtcgccttg
     3301 ccgtacgtat gattactgac ttcgtcagtt ttatctgcaa cctcaaagct gtactttgag
     3361 cagcttacgg ctagttttct agttttctct ttgatttcca ttgagtatta tttgtgggta
     3421 ccatctacaa gtgaagctat atgcgtaaac tacgtgagca attgaattcg aactagagag
     3481 gtaataataa atttatgcta tagttatggt gacttgtatg cttttgattc tagtttatca
     3541 aataatagat tagaattgtc agataatatc attttgtgtt ataatgaaga aaaaacagag
     3601 gtgttcaaat gtcagaagca ggtcataagt ttttagcaaa attggggaaa aaacgcttac
     3661 gtccaggtgg aaagcgtgcc acagattggt taattgcaga aggaggattt tcaaaagaaa
     3721 agagaatact agaggttgcg tgtaataggg gaactacagc aattgagttg gcacagcgtt
     3781 ttggttgcaa gataactgct attgatatgg atgctcaagc tttagaagtg gctaaaaaat
     3841 ctgctggaac ggcaggtgtt gctcatttaa tcagttttga aagagcaaat gcaatgaaac
     3901 ttccttatca agatgctagt tttgatattg ttataaatga agctatgctg actatgcaag
     3961 ccgatcaagc taagaaaaaa tgtgtaatgg aatatctaag ggtattaaaa cctggaggtc
     4021 ttctcttgac acatgatgtg cttcttaagg aagctaaaga gtctatcaga caggaattat
     4081 cacaagcaat tcatgtaaat gtaggtcctt taactcaaga tggttgggaa caggtgatga
     4141 tagaatcagg ttattgtgat gtgaaagcat tgactggtga aatgacatta atgaaattat
     4201 cgggtatgat ttatgacgaa ggtttgctag gaactttgaa aatttgtgta aatgcttgta
     4261 aaaaggagaa tagaaagcag tttttaacta tgtataaaat gtttgctaag aataaacaga
     4321 aattgggctt tattgcgatg gctagttata aatcgtcaaa acgttagata attattgaag
     4381 ttaacttttc cttttttctt tcttaaaaaa tatgctataa tagagagtaa aaaactttga
     4441 aagaaagaaa aagatgaatt taaaagatta cattgcaaca attgaaaatt atccaaagga
     4501 aggcattacc ttccgtgata ttagtccttt gatggctgat ggaaatgctt atagctacgc
     4561 tgttcgtgaa atcgttcagt atgctactga caagaaagtc gacatgatcg tgggacctga
     4621 agctcgtgga tttatcgtgg gttgtccagt tgcctttgag ttgggaattg gttttgcgcc
     4681 tgttcgtaag ccaggtaaat tgccacgcga agttatttct gctgactatg aaaaagagta
     4741 cggtgtcgat accttgacta tgcacgcgga tgccattaag ccaggtcaac gtgttcttat
     4801 tgtagatgac cttttggcga caggtggaac tgttaaggca actatcgaga tgattgaaaa
     4861 acttggtggt gttatggcag gttgtgcctt ccttgttgaa ttggatgaat tgaacggccg
     4921 tgaaaaaatt ggtgactacg actacaaagt tcttatgcat tattaatgaa aacagtccct
     4981 agggctgttt tctctacact aggatataaa aatagactat aactagttag agaaaaacta
     5041 taattgaaaa ctatatcttc ttgcagtata ataaaaggac taagtgtttg agatttgtct
     5101 tcaaacatat gcaattattc ctgaaagagt acagttagga gagggttatg ccgattcgaa
     5161 ttgataaaaa attgccagct gttgagattt tacggacaga gaatatcttt gtcatggatg
     5221 atcaacgtgc tgcccaccaa gatatccgtc ctttgaagat tttaatttta aatctcatgc
     5281 cacagaaaat ggtcacagag acccagttgt tgcgccactt ggctaataca cccctacaac
     5341 tggatattga ttttctctat atggagagcc accgttctaa aacaactcgt tcagagcaca
     5401 tggagacctt ctataaaact tttcctgaag tcaaggatga gtattttgat gggatgatca
     5461 tcacgggtgc tccagttgag catttaccat ttgaggaagt ggactattgg gaggaattta
     5521 gacagatgct tgagtggtct aagactcatg tctattcgac ccttcatatc tgttgggggg
     5581 ctcaggctgg gctttatctg cgctatggtg tagaaaaata ccagatggac agtaagctat
     5641 caggtattta tcctcaggac accctaaaag agggtcacct tctatttaga ggctttgatg
     5701 atagctatgt atcccctcat tcacggcaca cggagatttc taaggaagag gtcttaaaca
     5761 agaccaatct cgagatttta tcagaaggac ctcaggttgg ggtttctatt ttggccagtc
     5821 gtgatttacg agaaatttat agttttggtc atttggagta tgaccgtgat accttggcaa
     5881 aagagtattt tcgagatcgt gatgcaggtt tcgacccaca tattccagaa aattacttta
     5941 aagatgatga tgttaatcag gtaccttgtc tttgttggtc ttcatctgca gccctctttt
     6001 tcagtaattg gataaaccat gcggtctatc aggagacgcc ttttgattgg agaaagatag
     6061 aagatgatgc atctgcatat gggtatttat aagaggaatt atgacatatt tagacgcttt
     6121 taaatcaggt atcttggttt taccgagtgc cctgctcttg cattttaagg aactctttcc
     6181 ttctagcgac gattttctgg tttggcaatt tttctatttg caaaatacga caggcttaga
     6241 agaaatgtcg ccaagccaga ttgctgaaag gattggcaag gaaatttcgg atgtcaacca
     6301 gtccatttct aatctgacgg aaaggggact gctccagtat cgtactatcg aattaaatgg
     6361 cgaaattgaa ttgctctttg atgctagttt ggccttggaa cgtttggatg acctgtttgg
     6421 agcagttcat tcaagttcag accagctgac acctcaaaac cagctcaagg atttggtgga
     6481 aaccttccag caggagttgg gacgattgtt gacgcctttt gagattgagg atttgaccaa
     6541 gacactaaag gaagatggaa ccagtgctga cttgattaag gaggctcttc gtgaagctgt
     6601 tttgaatgga aaaccaaact ggaagtacat tcaggcgatt ttgagaaact ggcgccatga
     6661 aggaatcaag agtgtggctc aaattgaggc caagagagca gaaagagaag caagcaatcc
     6721 tcagttgaca caggtatctg cagatttcag aaatgccatg gatctctgga aggattaatc
     6781 catgcaagca ggcttgaaat ccgagtaaga tttgcaagct gtgtataatt gtgatagaat
     6841 aaaatagaaa ataaattgaa aaaagaggta tgtgaaatgt cacgtaaacc atttatcgct
     6901 ggtaactgga aaatgaacaa aaatccagaa gaagctaaag cattcgttga agcagttgca
     6961 tcaaaacttc cttcatcaga tcttgttgaa gcaggtatcg ctgctccagc tcttgatttg
     7021 acaactgttc ttgctgttgc aaaaggctca aaccttaaag ttgctgctca aaactgctac
     7081 tttgaaaatg caggtgcttt cactggtgaa actagcccac aagttttgaa agaaatcggt
     7141 actgactacg ttgttatcgg tcactcagaa cgccgtgact acttccatga aactgatgaa
     7201 gatatcaaca aaaaagcaaa agcaatcttt gcgaacggta tgcttccaat catctgttgt
     7261 ggtgaatcac ttgaaactta cgaagctggt aaagctactg aattcgtagg tgctcaagta
     7321 tctgctgcat tggctggatt gactgctgaa caagttgctg cctcagttat cgcttatgag
     7381 ccaatctggg ctatcggtac tggtaaatca gcttcacaag acgatgcaca aaaaatgtgt
     7441 aaagttgttc gtgacgttgt agctgctgac tttggtcaag aagtcgcaga caaagttcgt
     7501 gttcaatacg gtggttctgt taaacctgaa aatgttgctt catacatggc ttgcccagac
     7561 gttgacggtg cccttgtagg tggtgcgtca cttgaagctg aaagcttctt ggctttgctt
     7621 gactttgtaa aataatcagt aagtagcaaa agctaggtgg aacagcattc agatgtctgt
     7681 tacatttttt ataggagagg aaagattgaa aataaaaatt ggattagcaa gtatctgttt
     7741 actaggcttg gcaactagtc atgtcgctgc aaatgaaact gaagtagcaa aaacttcgca
     7801 ggatacaacg acagcttcaa gtagttcaga gcaaaatcag tcttctaata aaacgcaaac
     7861 gagcgcagaa gtacagacta atgctgctgc ccactgggat ggggattatt atgtaaagga
     7921 tgatggttct aaagctcaaa gtgaatggat ttttgacaac tactataagg cttggtttta
     7981 tattaattca gatggtcgtt actcgcagaa tgaatggcat ggaaattact acctgaaatc
     8041 aggtggatat atggcccaaa acgagtggat ctatgacagt aattacaaga gttggtttta
     8101 tctcaagtca gatggggctt atgctcatca agaatggcaa ttgattggaa ataagtggta
     8161 ctacttcaag aagtggggtt acatggctaa aagccaatgg caaggaagtt atttcttgaa
     8221 tggtcaagga gctatgatgc aaaatgaatg gctctatgat ccagcctatt ctgcttattt
     8281 ttatctaaaa tccgatggaa cttatgctaa ccaagagtgg caaaaagtgg gcggcaaatg
     8341 gtactatttc aagaagtggg gctatatggc tcggaatgag tggcaaggca actactattt
     8401 gactggaagt ggtgctatgg cgactgacga agtgattatg gatggtgctc gctatatctt
     8461 tgcggcctct ggtgagctca aagaaaagaa agatttgaat gtcggctggg ttcacagaga
     8521 tggtaaacgc tatttcttta ataatagaga agaacaagtg ggaaccgaac atgctaagaa
     8581 aatcattgat attagtgagc acaatggtcg tatcaatgat tggaaaaagg ttattgatga
     8641 gaacgaggtg gatggtgtca ttgttcgtct aggttatagc ggtaaagaag acaaggaatt
     8701 ggcgcataac attaaggagt taaaccgtct gggaattcct tatggtgtct atctctatac
     8761 ctatgctgaa aatgagaccg atgctgagaa tgacgctaaa cagaccattg aacttataaa
     8821 gaaatacaat atgaacctgt cttaccctat ctattatgat gttgagaact gggaatatgt
     8881 aaataagagc aagagagctc caagtgatac agatacttgg gttaaaatca tcaacaagta
     8941 catggacacg atgaagcagg cgggttatca aaatgtgtat gtctatagct atcgtagttt
     9001 attacagacg cgtttaaaac acccagatat tttaaaacat gtaaactggg tagcggccta
     9061 tacgaatgct ttagaatggg aaaaccctta ttattcagga gaaaaaggtt ggcaatatac
     9121 ctcttctgaa tacatgaaag gaatccaagg gcgcgtagat gtcagcgttt ggtattaagc
     9181 aatgatttga aagagggatg tgatagtagc accctctttt tctttgtttt atgatagttc
     9241 atcctcgagt aaattcaaga tcttgctcgg aaatgaagct tatatagtag attgaatata
     9301 gacaaatacc ttgtgattgg taaaacattt tagaaattca tttacctttc ctaatcgact
     9361 tggtttcatc ttatttcaat ctattatagt attggggaat ttcttcaaac cacatcagct
     9421 tggtcagttc tacctgcgac ctcaaaactt gtgctttggt caagctgggt ttagtttcct
     9481 agtttgctga tggatttcca ttgactataa gcatccaaac ctcttttttg tcttctaaag
     9541 aattcttaaa ttatcagtct attgcaactt ttctcatata agttctttgt cttgctattg
     9601 gttttcctta gtagtatact aaggtagtaa tcattaagaa gtggttacaa aaaataatga
     9661 atgaggtaaa gaaaatggta gaattgaaaa aagaagcagt aaaagacgta acatcattga
     9721 caaaagcagc gccagtagca ttggcaaaaa caaaggaagt cttgaaccaa gctgttgctg
     9781 atttgtatgt agctcacgtt gctttgcacc aagtgcactg gtatatgcat ggtcgtggtt
     9841 tccttgtatg gcatccaaaa atggatgagt acatggaagc tcttgacggt caattggatg
     9901 aaatcagcga acgcttgatt acactcggtg gaagcccatt ctctacattg acagagttcc
     9961 ttcaaaatag tgaaatcgaa gaagaagctg gtgaataccg taatgttgaa gaaagcttgg
    10021 aacgtgttct tgttatctac cgttacttgt cagaactttt ccaaaaaggt ttggatgtca
    10081 ctgatgaaga aggtgacgat gtgacaaacg gtatctttgc aggcgctaaa actgaaacag
    10141 ataaaacaat ttggatgctt gcagccgaac ttggacaagc acctggtttg taagaaataa
    10201 ggaaacatag ataaatctgt aggaaatttc ttacagattt tttctatttt gtaagctatt
    10261 ccaaaccagt ctttttttga gttttttgat aaaatagtac tatcagtgaa aaggatggaa
    10321 gcatgactaa gaaaatcgta gctatttggg cccaggatga agagggtgtg attggtaaga
    10381 aaaatcgtct gccttggcat ttgccagcag aattgcagca ctttaaagaa acaactctga
    10441 atcatgctat cttgatgggg cgtgtgacct ttgatgggat ggggcgtcgc ttgcttccaa
    10501 aacgggaaac cttgattttg acgcgtaatc cggaagaaaa gatagatggg gttgctactt
    10561 ttcaggacgt ccagtctgtt cttgactggt atcaggctca agaaaagaat ctctacatta
    10621 tcggtgggaa gcaaattttt caggcttttg aaccttacct tgatgaagtg attgtcactc
    10681 acattcatgc tcgggtggaa ggagatacct atttccctga agaacttgac ttgtctcttt
    10741 ttgagacagt ttcaagcaaa ttttacgcca aagatgagaa gaatccttat gattttacca
    10801 tccaataccg caagagaaag gaagtctaat ggaacggagt ttatttggtc tattcacggc
    10861 ttttctgtgt ttcatctgct ttctggcagg agcacaagct tttcgtaaaa agcgttacgg
    10921 gctttctatc ctcctttggt taaatgcttt taccaatctg gtcaatagta ttcatgcttt
    10981 ttacatgacc ttattttaga tagaatgaca gtatagaatg gaaggaaatc atgtctacaa
    11041 atagaaaaaa tgatatgatg gtttattgct cattttgtgg caaaaaccaa gaagaagtac
    11101 aaaaaataat tgctggcaac aatgctttta tttgtaatga atgcgtggag ttagctcagg
    11161 aaatcattcg agaagaattg gttgaggaag tcttggcaga cttgtctgag gtgccaaaac
    11221 caattgaact cctccatatc ttgaaccact atgtaattgg tcaagatcgt gccaagcgtg
    11281 ccttggcagt ggcggtttat aaccactaca aacgcatcaa tttccacgat acacgcgaag
    11341 agtcagaaga tgtggatttg cagaagtcaa acattttgat gattggccca actggttcag
    11401 ggaaaacttt ccttgcccag accttggcta agagcttgaa tgtacctttt gctattgcgg
    11461 atgcgacagc tctgacggag gctggttatg tgggtgagga tgtggaaaat atccttctca
    11521 aactcttgca ggttgctgac tttaacatcg aacgtgcaga gcgtggcatt atctatgtgg
    11581 atgaaattga caagattgcc aagaagagtg agaatgtgtc tatcacacgt gatgtttctg
    11641 gtgaaggggt gcaacaagcc cttctcaaga ttatcgaggg aactgttgct agcgtgccgc
    11701 ctcaaggtgg acgcaaacat ccacaacaag agatgattca agtggataca aaaaatatcc
    11761 tcttcatcgt gggtggtgct tttgatggta ttgaagaaat tgtcaaacaa cgtctgggtg
    11821 aaaaagtcat cggatttggt caaaacaata aggcgattga cgcaaacagc tcatacatgc
    11881 aagaaatcat cgctgaagac attcaaaaat ttggtattat ccctgagttg attggacgct
    11941 tgcctgtttt tgcggctctt gagcaattga ccgttgatga cttggttcgc atcttgaaag
    12001 agccaagaaa tgccttggtg aaacaatacc aaaccttgct ttcttatgat gatgttgagt
    12061 tagaatttga cgacgaagcc cttcaagaga ttgctaataa agcaattgaa cggaagacag
    12121 gggcgcgtgg acttcgctcc atcatcgaag aaaccatgct agatgttatg tttgaggtgc
    12181 cgagtcagga aaatgtgaaa ttggttcgca tcactaaaga aactgtcgat ggaacggata
    12241 aaccgatcct agaaacagcc tagaggtgac tatggaactt aatacacaca atgctgaaat
    12301 cttgctcagt gcagctaata agtcccacta tccgcaggat gaactgccag agattgccct
    12361 agcagggcgt tcaaatgttg gtaaatccag ctttatcaac actatgttga accgtaagaa
    12421 tctcgcccgt acatcaggaa aacctggtaa aacccagctc ctgaactttt ttaacattga
    12481 tgacaagatg cgctttgtgg atgtgcctgg ttatggctat gctcgtgttt ctaaaaagga
    12541 acgtgaaaag tgggggtgca tgattgagga gtacttaacg actcgggaaa atctccgtgc
    12601 ggttgtcagt ctagttgacc ttcgtcatga cccgtcagca gatgatgtgc agatgtacga
    12661 atttctcaag tattatgaga ttccagtcat cattgtggcg accaaggcgg acaagattcc
    12721 tcgtggtaaa tggaacaagc atgaatcagc aatcaaaaag aaattaaact ttgacccaag
    12781 tgacgatttc atcctctttt catctgtcag caaggcaggg atggatgagg cttgggatgc
    12841 aatcttagaa aaattgtgag gaaaagaaaa tggcaaaaac aattcataca gataaggccc
    12901 caaaggctat cggaccctat gttcaaggaa aaatcgttgg caaccttttg tttgctagcg
    12961 gtcaagttcc cctatcccct gaaactgggg aaattgtagg agagaatatc caagaacaga
    13021 cagagcaagt cttgaaaaac atcggtgcta ttttggcaga agcaggaaca gactttgacc
    13081 atgttgtcaa aacaacttgc ttcttgagcg atatgaacga ctttgttcct tttaatgagg
    13141 tttaccaaac ggccttcaaa gaggaattcc cagctcgttc agctgtggag gtagctcgtc
    13201 ttcctcgtga tgtaaaagtc gaaattgaag tcatcgcaga gattggataa gctagttgaa
    13261 gtttggtgtt gccaaacttc ttttgatata aggagaaaaa gatgacaaag aaacaacttc
    13321 acttggtgat tgtgacaggg atgagtggcg cagggaaaac tgtagccatt cagtccttcg
    13381 aggatctagg ttatttcacc attgataata tgccgccagc tctcttgcct aagtttttgc
    13441 agctggttga aattaaggaa gacaatccta agttggcctt ggtagtggat atgcgtagcc
    13501 gttctttctt ttcagagatt caagctgttt tggatgagtt ggaaaatcaa gatggtttgg
    13561 atttcaaaat cctctttttg gatgcggctg ataaggaatt ggtcgctcgt tacaaggaaa
    13621 ccagacggag tcacccacta gcagcagacg gtcgtatttt agatggaatc aagttggaac
    13681 gtgaactctt ggcacctttg aaaaatatga gccaaaatgt ggtggatacg actgaactca
    13741 ctccacgtga gctgcgcaaa acccttgcag agcagttttc agaccaagaa caagcccagt
    13801 ctttccgtat cgaagtcatg tctttcggat ttaagtatgg aatcccgatt gatgcggact
    13861 tggtctttga tgtccgtttc ttgccaaatc cctattatct accagaactg agaaacaaaa
    13921 cgggtgtgga tgaacctgtt tatgattatg tcatgaacca tcctgagtca gaagactttt
    13981 atcaacattt attggccttg attgagccga ttctgccaag ttaccaaaag gaaggtaagt
    14041 ccgttttgac cattgccatg ggatgtacgg gtggacaaca ccgtagtgtg gcatttgcta
    14101 aacgcttggc gcaggactta tccaagaatt ggtctgttaa tgaagggcat cgcgacaaag
    14161 accgcagaaa ggaaacggta aaccgttcat gagaaaacca aagataacgg tgattggtgg
    14221 agggactgga attcccgtca ttctaaaaag tctgcgggaa aaagatgtgg aaatcgcagc
    14281 tatcgtgacg gtggcagatg atggtggttc ttcaggtgaa ctccgaaaaa atatgcaaca
    14341 gttgacaccg ccaggtgatc ttcgtaatgt ccttgtggcc atgtcggata tgcctaagtt
    14401 ttatgagaag gtctttcagt atcggttctc tgaggatgcc ggagcctttg ctggccatcc
    14461 attgggaaat ctcatcattg ctggcttgtc agaaatgcag ggttcaacct ataatgccat
    14521 gcagttattg agcaaatttt tccatacaac agggaaaatt tatccttcca gtgaccatcc
    14581 tttgaccctt catgcagtct ttcaggatgg gacagaagtg gctggagaga gtcatattgt
    14641 agaccatcga ggcataattg acaatgtcta tgtgaccaat gccctaaacg atgatacgcc
    14701 tctggccagc cgtcgagtag tgcagaccat ccttgaaagt gacatgattg tcctagggcc
    14761 aggttccctc tttacctcta ttttgcccaa tatcgtgatt aaggaaattg ggcgggctct
    14821 tttggaaacc aaggcagaaa ttgcctatgt ctgcaatatc atgacccaac gtggggagac
    14881 ggaacacttt acagatagcg accacgtgga agtcttgcat cgtcaccttg gtcgcccttt
    14941 tatcgacact gtcttggtga atattgaaaa agtgcctcag gaatacatga attccaaccg
    15001 ttttgatgaa tacttagtgc aagtggaata cgattttgta ggtctttgta agcaagtttc
    15061 gcgcgtgatt tcatctaact tccttcgtct ggaaaatggc ggtgccttcc acgatggaga
    15121 tttgattgtg gacgagttga tgcgcattat acaggtgaaa aaatgagttt cacagtagca
    15181 gtaaaagaag aaatcctggg ccaacaccat ctgagctggt atgaattatc tgccattatc
    15241 aaaatgtctg gtagcatcgg tctctcgact tcgggcttga ctttgtcagt tgtgacagaa
    15301 aatgccaaac tggcccgtca cctctatgag tcctttctcc atttctatga aatcaaatct
    15361 gaaattcgtc accaccaacg gagcaatctt cgcaagaatc gcgtctatac cgtttttaca
    15421 gatgaaaagg tgcaggattt gttaagtgat ttgcacttgg cagactcttt ctttggcctg
    15481 gaaacaggta ttgatgaggc gattttatcg gacgaggaag caggtcgtgc ctatctctgt
    15541 ggcgctttct tggcaaatgg gagcattcgt gaccctgagt caggcaagta ccagttggaa
    15601 atcagttctg tttatctgga ccacgcgcaa ggaattgcct cccttctcca acagttttta
    15661 ctggatgcca aggtgcttga gcgcaagaag ggggctgtga cctatctcca gcgagcagaa
    15721 gacattatgg acttcttgat agtaatcgga gccatgcagg cacgtgatga ttttgagcgg
    15781 gttaagattt tgcgagaaac ccgtaacgac ctcaatcggg ctaataatgc cgagacagct
    15841 aatatcgctc ggacagtttc tgccagcatg aagaccatta acaatatcag taaaatcaaa
    15901 gatatcatgg gcttagaaaa tttgccagta gatttgcagg aagtggcgca actgaggatt
    15961 cagcacccag actactctat ccagcagtta gcagatagtc tcagcacccc tctgaccaaa
    16021 agtggtgtca atcacagact cagaaaaatc aataagatag cggatgaatt ataaaaccac
    16081 gaatcctatg tgactcgtgg ttctttttta taaactggta gagtgttttg gttgtacttt
    16141 ttgttcaggg tcaatgtagt tgatagcgtt gttgacagca gttggagctt ctccgaggcc
    16201 tgtcgcaatc agatcaattt ttccgtcata gtagcagcag tcaccgatag catagatacc
    16261 tgcttggctg gattcctgtt tgctgttgac gataatcttg tgacggttga ggtcgagccc
    16321 ccagttttta aggttaccga cagaagattt gaaaccatag ttgacaaaga ggtggtctag
    16381 atcaatggtt tcagtttcat cagatttgac ttttgtgatt tcaagtttat caagtgtttt
    16441 tccatttcca aggagttggc taggggcgaa tggtgtcttg atggttacag atgattcttg
    16501 caaggcttga acactgtgtt ccaaggcacg gaaattatct ctgcggtgaa caagggtagt
    16561 tggtgcgatt ttttcaaaag ccaaagccca atccacagcc gagtctcccc caccaagaat
    16621 cgtcactttc ttaccagcgt attgctgaat gttagaaacg tggtagtgga tattttcata
    16681 gccctcaacc ccttcaagtt ccagcggacg tggtttgaag gcaccgccac ccatagcgat
    16741 gataactgtt ttagtcaggt gacttccttt agaagttgtg atggcaaatt cttcttcttg
    16801 tttgtcaatc tcaagaaccg tttcattgag atgaataggg gtatcaaatc catttagctg
    16861 ttcaatcaag cggttagtca actcttctcc agtcaggttt gggaagcctg gtacgtctag
    16921 gatttccttt tcagggtaga gaatagcagg ttgtccacct agctggggaa gagagtcgat
    16981 gatttgaacc ttggcttggc gtaggtgggc ataaaaggct gcaaaaagcc cgacaggacc
    17041 accacccaca atggtaatat catagagttg agacatagtt tctcctttgt tttttctagt
    17101 cagtttattt tatcatattt ttgttcaatg taaaatggac taggataggg aaaaaaatgc
    17161 cagaaaatgg tataatagga cgaaagtgtt ttgataggga ggatatcagg gatgaatttt
    17221 caacaattat ccaatctgca atattggacc agtttgtttg caagtccatg gacgatagct
    17281 atcaatctga ttgatatttt gattgttgct tatattttat accattttac aaaagctatt
    17341 gcaggaacca agattatgat tttggtacgt ggagttttgg tgtttatttt agctcaaatc
    17401 cttgcaaata tgattggttt gactacgatt tcttggttaa tcaatcaaat tattacttat
    17461 ggggttattg cggcggttgt tatcttctct ccagagattc ggactggttt ggaacgtttg
    17521 ggaagagcga cagatttctt ttccaatgcc cctattagtg ctgaggaaca gatgattcgt
    17581 gcctttgtta agtctgttga atacatgagt cctcgtaaaa tcggggcctt ggttgctatt
    17641 cagcgtgtac gtaccttgca ggagtatact tcgacaggaa ttcccttgga tgctaagatt
    17701 tctgcagaac ttctcattaa catttttatt cccaacactc ccctacatga tggtgcggtg
    17761 attatcaaag aagaacgtat cgctgtgacg tctgcctatc tgcccttgac aaaaaacaca
    17821 gggatttcca aggaatttgg gaccagacac cgggcggcta tcggtttatc agaagtctca
    17881 gatgccttga cttttgtcgt atcagaggaa acgggaggaa tttcgataac ctataatgga
    17941 aggtttaagc acaacctaac acttgatgaa tttgaaacag aattacgtga aatcttactt
    18001 ccaaaagagg aagtgggtct tagttttaaa gaacgattgc taggaggatg gaaacatgaa
    18061 aaaaaatagt ttatatatca tatcctcact cttttttgct tgtgtcttat ttgtctatgc
    18121 tacggcgacg aattttcaaa acagtaccag tgctaggcag gtaaaaacgg aaacctatac
    18181 taatacagta acaaatgtcc ctattgacat acgctataat agtgataagt attttattag
    18241 cggttttgct tcagaagtat cagtggtctt gactggtgca aatcgcctat cgctagctag
    18301 tgaaatgcaa gaaagtacac gtaaattcaa ggttactgct gacctaacag atgccggtgt
    18361 tggaacgatt gaagttcctt tgagcattga agatttaccc aatgggctga ccgctgtggc
    18421 gactccgcaa aaaattacag tcaagattgg taagaaggct cagaaggata aggtaaagat
    18481 tgtaccagag attgacccta gtcaaattga tagtcgggta caaattgaaa atgtcatggt
    18541 gtcagataaa gaagtgtcga ttacgagtga ccaagagaca ttggatagaa ttgataagat
    18601 tatcgctgtc ttgccaacta gcgaacgtat aacaggtaat tacagtggtt cagtaccttt
    18661 gcaggcaatc gaccgcaatg gtgttgtctt accggcagtt atcactccgt ttgatacaat
    18721 aatgaaggtg actacaaaac cagtagcacc aagttcaagc acatcaaatt caagtacaag
    18781 cagttcatcg gagacatctt cgtcaacgaa agcaactagt tcaaaaacga attaaaaata
    18841 gaaaaggatt ttataacaat gggtaaatat tttgggactg atggagtccg tggagaagct
    18901 aacctagaac taacaccaga attagccttt aaactaggac gttttggagg ctatgttctt
    18961 agtcaacatg aaacggaagc gccgaaagtc tttgtaggac gtgacacacg tatttcaggg
    19021 gaaatgctgg aatcggcctt ggtggcaggt ctcctttcag tagggattca cgtatacaaa
    19081 cttggtgtcc ttgcaacacc agcagtagct tacttggttg aaactgaagg agcaagtgcc
    19141 ggtgtcatga tttctgctag ccacaaccca gcccttgata acggaatcaa gttctttggc
    19201 ggtgatggct tcaaactaga tgatgaaaaa gaagcagaaa ttgaagcctt gctagatgct
    19261 gaggaagaca ctcttcctcg tccaagtgca gaaggcttag gaattttggt agattatcca
    19321 gaaggcttgc gtaagtatga aggatacctt gtttcaactg gaactcctct tgatggaatg
    19381 aaggttgcct tggatacagc taatggagca gcttctacca gtgcccgtca aatctttgca
    19441 gaccttggtg cccaattgac ggttatcggg gaaacaccag acggtcttaa catcaacctt
    19501 aatgttggtt caacacatcc agaagccctt caagaagtgg tcaaagaaag tgggtcagct
    19561 attggtttgg cctttgatgg agacagtgac cgcttgattg ctgttgatga gaatggtgac
    19621 atcgtcgatg gtgacaagat tatgtacatc atcggaaaat acctttctga aaaaggacaa
    19681 ttggctcaaa atacaattgt gacaactgtt atgtctaacc ttggtttcca caaggccttg
    19741 aatcgcgaag gtattaacaa ggcagttact gcagttggtg accgctacgt tgttgaagaa
    19801 atgagaaaat caggctacaa ccttggtggt gaacagtctg gtcacgttat cttgatggat
    19861 tacaatacca caggtgatgg tcaattatca gcagttcaat tgactaaaat tatgaaggaa
    19921 actggtaaga gcttatcaga gttggcggca gaagtaacga tttatccaca aaaattagtt
    19981 aatatccgag tggaaaacgt catgaaggaa aaggccatgg aagtgccagc tatcaaggcc
    20041 atcatcgaga agatggaaga agaaatggcg gggaacggcc gtatccttgt tcgtccaagt
    20101 ggaacagagc ccctcttgcg tgttatggca gaagcgccta caacagaaga agtggactac
    20161 tatgttgata ctatcacaga tgtagttcgt gctgaaattg ggattgacta aatcctagaa
    20221 aactagatga aaataaaaaa ttatggtaca atagcttata atattgtagc cgatggagaa
    20281 agacatgaat cttaaacgtg aacaagaatt tgttagtcag tatcattttg atgcgcgtaa
    20341 ttttgaatgg gaaaatgaaa atggagctcc tgaaaccaag gtggatgtga atttccaatt
    20401 gctccaacat gaccaagaaa atcaagtgac ttccttgatt gtcatcttga gctttatgat
    20461 tgtatttgat aagtttgtca ttagtggaac aatctcacaa gtaaaccata tcgatggccg
    20521 tattgtcaat gaaccaagtg aattgaacca agaagaggtg gaaaccttgg ctcgtccatg
    20581 tttgaacatg ctcaatcgtt tgacttacga agtgactgaa attgcattag acttaccagg
    20641 aattaatttg gagttctaat atgaaattag ctgttttcac agattcctct gcttatctca
    20701 gtgaagagac cttgcaaaga gaagacttgt ttgtcttgga tattcctgtc aatattgatg
    20761 gtgaggaata tgtcgaaggc atcaatctgt ctgctgagga attttaccaa aaaatggctc
    20821 aggcttctga attgcctaag accagtcaac caagtattgc caagttagat gagatcttaa
    20881 cttcgctcaa agaacaaggt tatacacatg ccttggggct tttcctatct tctggaattt
    20941 caggttttta ccaaaatatc cagtatatgg tcgatgacta tgagggctta accattgctt
    21001 tctcagacac tttgattaca agtgctcccc taggcatcat ggttgaaagc gtctttaatt
    21061 ggcgtgatca gggcgatgat tttgccagca ttcaggataa gctagccatt caaatcagcc
    21121 gtacgtcagc ctttatcatg gtagatgact tggatcattt ggtaaaaggt ggacgccttt
    21181 caaatggggc tgccattttg ggcaatttgc ttagcattaa gccaatcctt tattttaacg
    21241 atcaaggtgt gattgaagtt tacgaaaaag ttcgtactga aaagaaggcc accaagcgct
    21301 taattgaaat tatcaaggaa acaacggctt caggtcaata ccgggtcatt gtcattcatg
    21361 ggaatgctcc tgaaaaggct gaagaattgc gtcagcactt gcttgatttt ggcttgggtt
    21421 cggatgtttc acttgctaca tttggtagtg tcattggaac gcacctagga gcaggaagta
    21481 ttgctctggg ttatattcca gtgatttagt tggcgcttct aggctagtta agatgccttg
    21541 tatcttagaa attgaacacg gactacctgc ctcttgaaaa aagatgcctg tcttgccttt
    21601 cgtggaaagt cagtgccatt ccctatcttt cagaggcagc taaggtcctt tgtatcttga
    21661 taattgaaca cgcctggaac cctgtgtgaa aaagatagtt cttccaagaa gtagacactt
    21721 cttgattgga attcctattt tcactttgtg ttcttacgga ctttgtatct tagacaggag
    21781 tagagatgag tattcgagta attattgccg gttttaaggg aaagatgggc caggctgctt
    21841 gtcagatggt attgactgat ccagacttgg acttggtagc agttttggat tcttttgagt
    21901 ctgagtcaga atggcagggt attcctgttt tcaaggataa ggctgattta gctggttttg
    21961 aagcggatgt ctgggtagat tttactactc cagctgttgc ctacgaaaat acacgttttg
    22021 ctcttgaaaa tggctttgct ccagtagttg gaacgactgg tttcacgagt gaagaaattg
    22081 cagagctaaa agaattttct cgtgcccaag acttgggtgg cctgattgcc cctaactttg
    22141 ccttgggtgc tgtcttactc atgcaatttg cgacgcaggc tgccaaatat ttcccaaatg
    22201 tggagattat tgagctccat catgacaaga aaaaggatgc tccgagtgga acagccatta
    22261 aaacagctga gttgatggca gaggttcgag agtccattca gcaaggcgca gcagatgagg
    22321 aagagctgat tgctggtgct cgtggtgctg actttgatgg tatgcgcatc cactcagttc
    22381 gtttgccagg cttggtagct catcaggaag tcatctttgg caatcaggga gaagggttga
    22441 ccctccgtca tgactcctat gatcgcatct ccttcatgac aggagtcaat ttgggaatta
    22501 aagaagttgt caagcgtcat gagcttgtct atggattaga acacttatta tgagattaac
    22561 gcaaatgcct tctgaatttc agaaggcttt accagtatta gaaaaaatta aagaagcagg
    22621 ctttgaggct tattttgttg ggggctctgt tcgagatgcc cttctccata gccctatcca
    22681 cgatgtggat attgcgacgt cttcttatcc agaagagacc aagcagattt ttccgcgaac
    22741 agccgatatc ggaatcgagc atggaaccgt cttggtctta gatggggatg aggagtatga
    22801 ggtaacaacc tttcggacag aggatgtcta tgtggactat cgcagaccca gtgcggtttc
    22861 ctttgtgcgc tcgctagaag aagacctcaa acgtcgtgat ttcacagtca acgcctttgc
    22921 cttggatgag acaggagaaa tcgttgactt gttccatggt ttagaagatt tggaaaagca
    22981 agtcttgcga gcagttggag tggctagtga gcgtttcaac gaagatgctt tacggattat
    23041 gcgtggtttc cgttttcagg ctagtcttgg ttttgcactt gagccagaaa catttaaagc
    23101 tatgaagacc ttgacgccgc ttttggagaa aatttctgta gagcgtacct tcgtcgaatt
    23161 tgataaactc ttgctggctc cattttggag aaggggcttg gcttccatga ttgagagtca
    23221 agcttatgac tatctccctg atatggcatc tagccaggac aagctcaaca gactgtttga
    23281 tttggagact gattttactt ttgaatcctc tgaacaagcc tgggcggctt tactatgggc
    23341 tttggagatt gaaaatgcgc agtcattttt gaaatcttgg aagacctcac gccagtttgc
    23401 caagcaagtt caggatttgc tgattatttt ggctctgcgt gaaaatggag aattgagcaa
    23461 gcgagattgt tatcgctttg acatagattt gcttttacag gctgaaaatc ttcgtcaagc
    23521 tcaaggaaaa gaagtcaacc cacaagccat cacagaaaaa taccaaagct tgactatcca
    23581 tgacaagaaa gagattcaga ttaatggcga tattttgatc aaggaatatg gctatcagcc
    23641 aggcccagac ttgggagaga ttttaacaga gattgagttt gccattgtcg atggagaatt
    23701 ggagaataat cgtgaagcca tccatgctta cctgagggag aaaaaatgag tgattttatc
    23761 gttgaaaaac taagtaaatc cgttggtgac aagaccgttt ttagggatat ttcctttatt
    23821 atccatgact tagacagaat tggtttaatc ggtgtcaatg ggactggcaa gaccaccctt
    23881 ttggacgtcc tttctggtgt ttctggcttt gatggggatg tcagtccttt ttcagctaaa
    23941 aatgattacc agattggtta cttgactcag gatcctgatt ttgatgatag aaagacagtt
    24001 ttggatacgg ttctatctag tgaactcaag gaaatccagc tcattcgtga gtatgaattg
    24061 attatgctcg actatagtga ggacaagcag gcgcgtttgg aacgtgtcat ggcagagatg
    24121 gactctctcc aagcttggga aattgagagt caggtcaaga ccgttcttag caaattgggc
    24181 attcaagact tatctactcc tgttggggaa ttgtcaggtg gtctgagaag acgggtacag
    24241 ttggcacaag tcttacttgg caaccacgac ctcttgcttt tggatgagcc gaccaaccat
    24301 ctggatattg cgattattga gtggctgacc ctctttttga aaaattctaa gaagaccgtc
    24361 ctttttatca ctcacgatcg ttatttctta gacgctttgt caacacggat tttcgagttg
    24421 gagcgagcag gcttgacaga atatcagggc aattaccagg actatgttcg ccttaaggca
    24481 gaacaggacg agcgcgatgc agctctactt cataaaaaag aacaactcta caaacaagaa
    24541 ctggcctgga tgcgcagaca accgcaggca cgtgcgacca agcaacaagc tcgtatcaat
    24601 cgtttccatg atctgaaaaa ggaagtttca ggcagtagtg ctgagacaga tttgactatg
    24661 aactttgaaa ccagtcggat tgggaagaaa gtcatcgagt ttcaggatgt ttcctttgcc
    24721 tatgaaaata agcctatttt gcaagatttt aatctcttgg tgcaggccaa agaccgtatt
    24781 ggaattgttg gggacaatgg tgttggaaaa tcaaccctac ttaacctgat tgcaggaagt
    24841 cttgagccga cagcaggaca agttgtgatt ggggaaactg ttcgcatcgc ctatttctct
    24901 caacaaattg agggtttgga tgaaagcaag cgtgtgatca attacctgca ggaagtggca
    24961 gaggaggtca agaccagtgg tggttctacg acttccatcg ctgagttgct ggagcaattc
    25021 ctcttcccac gttcgacgca tgggaccttg attgagaaat tgtcaggggg tgagaaaaaa
    25081 cgtctttatc tcctcaaact gcttttggaa aaaccaaatg ttcttctttt agacgagcca
    25141 accaatgacc tagatattgc aactttgaca gtcttagaaa atttcttgca aggttttgca
    25201 ggtcccgttt taacagtcag tcacgaccgc tatttcttgg ataaggtagc gaccaagatt
    25261 ctcgcttttg aggatggtaa gattcgtcct ttctttggtc attacaccga ctatcttgat
    25321 gaaaaagctt ttgaaacaga tatggccaat caagtgcaaa aggccgaaaa ggaaaaagtg
    25381 gtcaaggttc gagaagacaa gaaacgcatg acctaccaag aaaagcagga gtgggcaagt
    25441 attgaaggtg atattgaaac cttggaaaaa cgtatcgctg ctattgaaga ggaaatgcag
    25501 gctaacggct ctgactttgg taagctggct actctccaaa aagaattgga tgagaaaaat
    25561 gaagcactcc ttgaaaaata cgaacgctat gagtatctca gtgaatttga tagttaagac
    25621 tattcgaaaa tcaaagtgca aactatgtcg gcttcacatt gccgactcaa gtacagcctg
    25681 tgaccggctt cctaatttgc actttgattt ttattgagta taaaagaata gaaaaatccc
    25741 gtctcatgaa aggatttctc tattcttttt tggtttcttg atgaaagata ttttgccagg
    25801 tttcgtggcg acgccagata ctggtatgga tgataccatc taactcatag cagatgagtt
    25861 tggttttttg actgatggaa gtaatttgaa tgtccttgat agcagaattt aactcttttt
    25921 tggtcttata agcctcttta tccatctgct ctccatcttg gcgaatatag acaaaatcat
    25981 cagtcaagag ttcttctagt tggtttcctt ggtcaatcaa ttgttcacgc ataagcaatt
    26041 ttttatagac attgtctaaa atttcatcct cagggatagg tgctggttcg atatggacat
    26101 cggtatcaaa gacgccaaaa cgctcctcca gcatagactc gacctgatcc gcgatttcat
    26161 ggctttcaaa aacagacaag tcaggattca tctctagtgt aatatccagg tagatgttgc
    26221 taccgtaggt gcgacctctt tgcgatttga ccttgctgat tttgggaatt tccatgatag
    26281 ccttttggta gtcctcgagc aggcggtcgt caaagccatc tgaaagacta aaggaagact
    26341 cgatgaagat atcataggca gtcttcaaga taaagaaagt gatgatgata gcaaccagtt
    26401 tatccacaat cggataattg aaactactag ctaggatggc aatggcggtt ccaagtgagg
    26461 taacagcgtc agaaagattg tccttagcag ctgccttcag cgccttggag ttggatttct
    26521 tactgaggcg agtattgtag agatagacca caaacataat cgctgcagaa atgattccta
    26581 gagttgcacc aagaggatca atgaccgttt cttcccgact gagaatcttt tgaatggtat
    26641 ctcttagaac atcgaaaccg acatagaaca tgatgataga agtgatcaag cttgccaaat
    26701 cttcaatctt ccaatgacca aaacggtggt cacggtctgc aggctggcgc gccatccgaa
    26761 tcccgattaa gagggccaca tttccaatga tgtccgatac gttattaaaa ccatcggcca
    26821 ccaaactgga tgaatgaagg agatgaccag ctgctaattt ggctgcagac aagatcaaat
    26881 aggtcgaaat actgataatg gctccacgct cagctaactt gagatttgag atagattgct
    26941 tcattcaact tcctttctag tcacatagca ttctaccatt atactggttt tcaaggaaaa
    27001 attcaaataa ggcagttttt actctttgaa aactccccaa aatttggtat aatggtacta
    27061 ctcaagggag tagctggcag aaacctgtga tagtgtcgtc attccgaatt ttatgctgaa
    27121 aagtatgctt tccggcccta tcttaaacag cgagacttgt tatgattaac aggtctcttt
    27181 ttgtttgtcg tgaaaagata tgacagaaag agagtctgtt ttgcacacaa tgtcaaggag
    27241 gagacacatg tcaaaagaac aaaaacgcca agcgttttat actcagagcc ctgaagaggt
    27301 cttgcaggct gtggatgcga ccgagcaagg tttgtcatca agtgaggcgg aaaagcgcct
    27361 tgccgaattt gggcacaatg aactcgaaga aggcgagaaa cgatcaatct tggtcaaatt
    27421 catcgagcaa tttaaggatt tgatgattat catcctagtt gcggcagcaa tcttgtcagt
    27481 cgtgacttct ggtggggaag atatcgcaga tgccattatc atcctagctg tggttatcat
    27541 caacgctgcc tttggtgttt accaagaagg aaaagctgaa gaagctattg aagccctcaa
    27601 atccatgtct agtccagttg cccgcgttct tcgtgatgga cacatggcag agattgactc
    27661 taaagaattg gtaccaggcg atatcgttgc ccttgaagca ggtgacgtgg taccagcgga
    27721 cctacgtttg atagaagcca actctcttaa aattgaagaa gcagccttga caggtgaatc
    27781 tgtaccagtc gaaaaagact tgtcagtcga gtttgcgaca gatgctggta ttggtgaccg
    27841 tgtcaacatg gccttccaaa actcaaacgt aacctatggt cgtgggatgg gtgttgttgt
    27901 caatacaggt atgtacactg aagttggtca tattgctggt atgcttcaag atgcggatga
    27961 gactgataca ccactcaaac aaaacttgaa caacctttct aaggtcttga cctatgctat
    28021 cttggtcatt gcccttgtta cttttgtagt gggtgtcttc attcaaggga aaaatccact
    28081 tggtgagttg ttgacttctg ttgcccttgc cgttgcagcc attccagaag gacttcctgc
    28141 tatcgttacc atcgttcttt ctcttggtac tcaagttttg gccaaacgac attccatcgt
    28201 tcgtaagttg ccagcagttg aaacacttgg ttcaactgaa atcatcgctt ctgataagac
    28261 tggtacgctg actatgaaca agatgacagt cgaaaaagtc ttctacgatg cggttctaca
    28321 tgactcagct gatgatattg aactaggtct tgaaatgcca ctacttcgtt cagttgtctt
    28381 ggccaatgat acgaaaatcg atgtggaagg taacttgatt ggtgacccaa ccgaaacagc
    28441 ctttatccaa tatgccttgg acaagggcta tgatgtcaaa ggtttcttag agaaatatcc
    28501 tcgtgtagct gaattgccat ttgactctga ccgtaagctc atgtcaacag ttcacccatt
    28561 gccagatggt cgtttccttg tagcagtcaa gggtgcgcca gaccaactct taaagcgttg
    28621 tcttcttcgt gataaggctg gggatattgc tccgattgat gagaaggtta caaatctcat
    28681 tcatacaaac aattctgaaa tggctcatca agccttgcgt gtccttgcag gtgcttataa
    28741 gattatcgat agtattccag aaaatctcac ttctgaagag cttgaaaatg atttaatttt
    28801 tactggtttg attgggatga ttgaccctga acgtcctgaa gccgctgagg ctgttcgtgt
    28861 ggctaaggaa gcgggaatcc gtccaattat gattacaggt gaccaccaag acacagcgga
    28921 agccattgcc aaacgtttgg gaatcattga cgcaaacgat acagaaggtc acgttttaac
    28981 tggtgctgaa ctcaatgaac tgtcagatga agaatttgaa aaagtcgttg gtcaatactc
    29041 tgtttatgcc cgtgtgtctc cagaacacaa ggttcgtatc gtcaaggctt ggcaaaaaca
    29101 aggtaaagtc gttgccatga caggtgatgg tgtcaatgac gcgccagctc tgaaaacagc
    29161 cgatatcggt atcggtatgg gaatcactgg tacagaagtt tctaaggggg cttctgacat
    29221 gattcttgca gatgataact ttgcgactat tatcgtcgca gtggaagaag gacgtaaggt
    29281 cttctcaaac attcaaaaga ctattcagta cctactttct gctaatactg ctgaagtatt
    29341 aaccatcttc ctatcaacct tgtttggttg ggatgtcttg cagccggttc atcttttgtg
    29401 gatcaacttg gtaacggata ccttcccagc tatcgctctt ggtgttgaac ctgcggagcc
    29461 tggtgtcatg aatcataaac cacgtggacg caaggcaagc ttcttctcag gtggtgtttt
    29521 gagttctatc atttatcaag gtgtactcca agcagctctt gttatgagtg tttatggcct
    29581 tgcgattgct tacccagttc atgtgggtga caatcatgct attcatgcag atgccctaac
    29641 gatggccttt gcaacccttg gtttgattca gctcttccat gcctacaatg tcaagtctgt
    29701 ctaccaatcc atcttgacag ttggcccatt caagtctaag acctttaact ggtccatctt
    29761 ggtatccttt atccttctca tggcaacaat cgttgtagaa ccgcttgaag gaatcttcca
    29821 cgtaaccaaa ctagacttgt cacaatgggg aattgttatg gctggaagct tctcaatgat
    29881 tatcatcgtc gaaatcgtta agtttattca acgcaaactc ggttttgaca agaatgcgat
    29941 ttaagggagg tttcggatgt cagcatatca attaccgact gtatggcagg atgaagctag
    30001 taatcaagga gcttttacgg ggctaaacag accaacagca ggtgcccgtt tcgaacaaaa
    30061 cttgccaaaa ggagaacaag cttttcagct ttattcactg ggaacaccaa atggtgtgaa
    30121 ggttactatc ttattggaag aattactaga agctggtttt aaggaagcgg cttacgactt
    30181 gtataagatt gctatcatgg atggggatca attcggctca gactttgtga agctcaatcc
    30241 aaattccaag attccagcct tattggacca gtcaggtact gaaaacgtaa gagtctttga
    30301 gtctgctcat attcttcttt accttgctga gaaatttgga gcctttttac caagtaatcc
    30361 tgtggaaaag atagaagttt tgaattggct attctggcaa gcaggtgcag caccttttct
    30421 aggtggggga tttggacatt tcttcaatta tgctcctgaa aaattggaat atcctattaa
    30481 ccgttttacg atggaagtga aacgccagtt ggatttattg gataaggaat tggctcagaa
    30541 accttatatt gcaggcaatg actatacgat tgcagatatt gctatctggt cttggtatgg
    30601 acagttagtt caaggaaatc tttaccaagg ttctgcaaaa ttcttggatg cctcaagtta
    30661 tcaaaatcta gtaaaatggg cagaaaaaat tgccaatcgt ccagctgtta agcgtggctt
    30721 ggaagtaact tatacagaaa ttaaatagca aaaaagtcat cttcggatgg ctttttgcta
    30781 cagttgaggg aaagggtttg cagttatcgg cttttgtgct ataattgcta taatatagta
    30841 aaaagcaaga ggagtgtgag gaagtggaaa agaaaattgt gaaggataac ttatttttat
    30901 ctcaagtgtc tcagccggca agtcaggagg acctttatct tgccagagat ttgcaggata
    30961 cactcttagc aaatcgtgat acctgtgttg gtctagctgc caatatgatt ggggtgcaga
    31021 agcgcgtgat tatctttaat cttggcttgg ttcccgtggt catgtttaac ccagtgcttc
    31081 tgtcctttga aggatcctat gaggcagaag aaggctgttt gtccttggta ggtgtgagat
    31141 caactaagcg ttatgaaacc ataaggcttg cctatcgtga cagcaagtgg caggaacaga
    31201 ccattacctt gacaggcttc ccagctcaga tttgccagca tgagctggat cacttggaag
    31261 gacgaatcat ttaggaggaa agcaaatgaa acgaatagtc tttgaactta tttttatcgc
    31321 aacgacctgg tatatctttt taccgcccct taacctgacc agctgggaat ttctcttctt
    31381 cctctgtggg catttgttag ttgtggcaat attatttggc tttggcaagg ggataaacct
    31441 tgtcaaaacg gttcatgtgc gccacggtaa ggcggaagct gccttaaatc ttgagggttt
    31501 caaaatcaat cggttaggga aaattctgtt agcttcgatt ggaggaattc ttctcttggc
    31561 agctttggtt tccttggtaa cttccagcat gtttcaggct aaaaattatg ccaatgtagt
    31621 cacggttacg gaaaaagact ttactgaatt tcctaagagt gacaccagta aggttcctat
    31681 cctagataga agtactgctg aaaaaattgg agaccgctac ttgggttccc taaccgataa
    31741 ggtgtcgcaa tacgtagcgg cagataccta tacccaattg acaattgatg ggaaacctta
    31801 tcgggtcaca ccactagaat atgcagaccc tatcaaatgg tttaacaatc aagccaaggg
    31861 aatcggtgag tatatcaagg tggacatggt aactggaaat gcggatttgg tggacttgaa
    31921 gacaccaatc aagtattcag actcggagta ttttaaccgt gatgtcaaac gtcacctgcg
    31981 cttgaagtac ccgaccaaaa tctttaaaac tccatctttt gaggtggacg atgagggcaa
    32041 tcctttctat gtagcaacgg tttaccaaaa gcaatttgga cttgctgttc ctcgtcctgc
    32101 ttcagtcatt atcttggatg ctacaaatgg agaaaccaag gaatacagct tatcagatgt
    32161 tccagaatgg gtggacagga tctatccagc agaggaaacc attgagcaaa tcaactacaa
    32221 cggcaagtac aaggacggtt tcttgaatgc catgatttcc aagaaaaacg tgacccagac
    32281 taccaatggc tataattact tgtctatcgg taatgacatc tatctctaca caggtgtgac
    32341 gtcggctaat gcggatgaga gtaatcttgg tttcatcctt gaaaatatgc gaacaggaga
    32401 aattactaag tatagcttgg cttctgcgac agaagaatca gcccgtgaat cagcagaagg
    32461 tgctgttcag gagaaatcct acaaagcaac cttcccaatc ctcatcaacc tcaatgacaa
    32521 gcctctctac atcatgggct taaaggacaa tgctggcttg gtcaaagagt acgccctggt
    32581 agacgcagtc gagtaccaaa atgttatcgt tgctactaca gtggaagaga tgctcagcaa
    32641 gtatgccaat aaaaacgacc ttgaaattga caatgcaacg acagaaagca tcaagggagt
    32701 agtagcagac ctcaaatcag ctgttatcaa gggagacact gtctacttct ttaaagttga
    32761 tggcaagata tacaaggtaa aggcttcagt atccgatgac cttccttacc ttgaaaatgg
    32821 taaaaccttc gaaggtcaag taggaaaaga caactatctc aagaccttta aagtacaata
    32881 atactcttcg aaaatctctt caaactacgt cagctctatc tgcaacctca aaacagtgtt
    32941 ttgagcagcc tgcggctagt ttcctagttt
//
LOCUS       DBEJAU010000020        32910 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC323 isolate 683620
            SAMN38261939-rid24807223.denovo.020, whole genome shotgun sequence.
ACCESSION   DBEJAU010000020 DBEJAU010000000
VERSION     DBEJAU010000020.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261939
            Sequence Read Archive: SRR26833919
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 32910)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 32910)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576303.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576303.1
            Genome Coverage       :: 154x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/19/2025 01:05:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,121
            CDSs (total)                      :: 2,078
            Genes (coding)                    :: 1,943
            CDSs (with protein)               :: 1,943
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 36
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 72 of 135
            Pseudo Genes (incomplete)         :: 63 of 135
            Pseudo Genes (internal stop)      :: 51 of 135
            Pseudo Genes (multiple problems)  :: 46 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..32910
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261939-rid24807223.denovo.020"
                     /strain="GPSC323"
                     /isolate="683620"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            complement(333..1181)
                     /gene="dprA"
                     /locus_tag="ACL29Z_000971"
     CDS             complement(333..1181)
                     /gene="dprA"
                     /locus_tag="ACL29Z_000971"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004257994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0009294 - DNA-mediated transformation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-processing protein DprA"
                     /protein_id="HGR0069301.1"
                     /translation="MKITNYEIYKLKKSSLTNQQILKVLEYGENVDQELLLGDIADIS
                     GCRNPAVFMERYFQIDDAHLSKEFQKFPSFSILDDCYPWDLSEIYDAPVLLFYKGNLD
                     LLKFPKVAVVGSRACSKQGAKTVEKVIQGLENELVIVSGLAKGIDTAAHMAALQNGGK
                     TIAVIGTGLDVFYPKANKRLQDYIGNDHLVLSEYGPGEQPLKFHFPARNRIIAGLCRG
                     VIVAEAKMRSGSLITCERAMEEGRDVFAIPDSILDGLSDGCHHLIQEGAKLVTSGQDV
                     LAEFEF"
     gene            complement(1279..1968)
                     /locus_tag="ACL29Z_000972"
     CDS             complement(1279..1968)
                     /locus_tag="ACL29Z_000972"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016779 - nucleotidyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0009058 - biosynthetic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sugar phosphate nucleotidyltransferase"
                     /protein_id="HGR0069302.1"
                     /translation="MKAIILAAGLGTRLRPMTENTPKALVQVNQKPLIEYQIEFLKEK
                     GINDIIIIVGYLKEQFDYLKEKYGVRLVFNDKYADYNNFYSLYLVKEELANSYVIDAD
                     NYLFKNMFRNDLTRSTYFSVYREDCTNEWFLVYGDDYKVQNIIVDSKAGRILSGVSFW
                     DAPTAEKIVSFIDKAYASGEFVDLYWDNMVKDNIKELDVYVEELEGNSIYEIDSVQDY
                     HKLEEILKNEN"
     gene            complement(1980..2858)
                     /locus_tag="ACL29Z_000973"
     CDS             complement(1980..2858)
                     /locus_tag="ACL29Z_000973"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000837620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DMT family transporter"
                     /protein_id="HGR0069303.1"
                     /translation="MKSKNGVPFGLLSGIFWGLGLTVSAYIFSIFTDLSPFVVAAAHD
                     FLSIFILLAFLLVKEGKVRLSIFLNIRNVSVIIGALLAGPIGMQANLYAVKYIGSSLA
                     SSVSAIYPAISVLLAFFFLKHKISKNTVFGIVLIIGGIIAQTYKVEQVNSFYIGILCA
                     LVCAIAWGSESVLSSFAMESELSEIEALLIRQVTSFLSYLVIVLFSHQSFTAVANGQL
                     LGLMIVFAAFDMISYLAYYIAINRLQPAKATGLNVSYVVWTVLFAVVFLGAPLDMLTI
                     MTSLVVIAGVYIIIKE"
     gene            complement(2848..3717)
                     /gene="licA"
                     /locus_tag="ACL29Z_000974"
     CDS             complement(2848..3717)
                     /gene="licA"
                     /locus_tag="ACL29Z_000974"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000411210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline kinase LicA"
                     /protein_id="HGR0069304.1"
                     /translation="MEKIIKEKISSLLSQEEEVLSVEQLGGMTNQNYLAKTTNKQYIV
                     KFFGKGTEKLINRQDEKYNLELLKDLGLDVKNYLFDIEAGIKVNEYIESAITLDSTSI
                     KTKFDKIAPILQTIHTSAKELRGEFAPFEEIKKYESLIEEQIPYANYESVRNAVFSLE
                     KRLADLGVDRKSCHIDLVPENFIESPQGRLYLIDWEYSSMNDPMWDLAALFLESEFTS
                     QEEETFLSHYESDQTPVSHEKIAIYKILQDTIWSLWTVYKEEQGEDFGDYGVNRYQRA
                     VKGLASYGGSDEK"
     gene            complement(3734..4756)
                     /locus_tag="ACL29Z_000975"
     CDS             complement(3734..4756)
                     /locus_tag="ACL29Z_000975"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004257983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribitol-5-phosphate dehydrogenase"
                     /protein_id="HGR0069305.1"
                     /translation="MINQIYQLTKPKFINVKYQEEAIDQENHILIRPNYMAVCHADQR
                     YYQGKRDPKILNKKLPMAMIHESCGTVISDPTGTYEVGQKVVMIPNQSPMQSDEEFYE
                     NYMTGTHFLSSGFDGFMREFVSLPKDRVVAYDAIEDTVAAITEFVSVGMHAMNRLLTL
                     AHSKRERIAVIGDGSLAFVVANIINYTLPESEIVVIGRHWEKLELFSFAKECYITDNI
                     PEDLAFDHAFECCGGDGTGPAINDLIRYIRPQGTILMMGVSEYKVNLNTRDALEKGLI
                     LVGSSRSGRIDFENAIQMMEVKKFANRLKNILYLEEPVREIKDIHRVFATDLNTAFKT
                     VFKWEV"
     gene            complement(4761..5468)
                     /locus_tag="ACL29Z_000976"
     CDS             complement(4761..5468)
                     /locus_tag="ACL29Z_000976"
                     /EC_number="2.7.7.60"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016465903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0050518 - 2-C-methyl-D-erythritol
                     4-phosphate cytidylyltransferase activity [Evidence IEA];
                     GO_process: GO:0019288 - isopentenyl diphosphate
                     biosynthetic process, methylerythritol 4-phosphate pathway
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="2-C-methyl-D-erythritol 4-phosphate
                     cytidylyltransferase"
                     /protein_id="HGR0069306.1"
                     /translation="MIYAGILAGGTGTRMGISNLPKQFLELGDRPILIHTIEKFVLES
                     SIEKIVVGVHGDWVSHAEDLVDKYLPLYKERIIITKGGADRNTSIKKIIEAIDAYRPL
                     TPEDIVVTHDSVRPFITLRMIQDNIQLAQNHDAVDTVVEAVDTIVESTNGQFITDIPN
                     RAHLYQGQTPQTFRCKDFMDLYGSLSDEEKEILTDACKIFVIKGKDVALAKGEYSNLK
                     ITTVTDLKIAKSMIEKD"
     gene            5804..7291
                     /gene="tacF"
                     /locus_tag="ACL29Z_000977"
     CDS             5804..7291
                     /gene="tacF"
                     /locus_tag="ACL29Z_000977"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000835918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV teichoic acid flippase TacF"
                     /protein_id="HGR0069307.1"
                     /translation="MKSIKLNALSYMGIRVLNIIFPILTGTYVARVLDRTDYGYFNSV
                     DTILSFFLPFATYGVYNYGLRAISNVKDNKKDLNRTFSSLFYLCIACTILTTAVYILA
                     YPLFFTDNPIVKKVYLVMGIQLIAQIFSIEWVNEALENYSFLFYKTAFIRILMLVSIF
                     LFVKNEHDIVVYTLVMSLSTLINYLISYFWIKRDIKLVKIHLSDFKPLFLPLTAMLVF
                     ANANMLFTFLDRLFLVKTGIDVNVSYYTIAQRIVTVIAGVVTGAIGVSVPRLSYYLGK
                     GDKEAYVSLVNRGSRIFNFFIIPLSFGLMVLGPNAILLYGSEKYIGGGILTSLFAFRT
                     IILALDTILGSQILFTNGYEKRITVYTVFAGLLNLGLNSLLFFNHIVVPEYYLLTTML
                     SETSLLVFYIIFIHRKQLIHLGHIFSYTVRYSLFSLSFVAIYFLINFMYPVDMVINLP
                     FLINTGLIVLLSAISYISLLVFTKDSIFYEFLNHVLALKNKFKKS"
     gene            7301..8104
                     /locus_tag="ACL29Z_000978"
     CDS             7301..8104
                     /locus_tag="ACL29Z_000978"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004259727.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphorylcholine transferase LicD"
                     /protein_id="HGR0069308.1"
                     /translation="MKQLTVEDAKQIELEILDYIDTLCKKHNINYIINYGTLIGAVRH
                     EGFIPWDDDIDLSMPREDYQRFINIFQKEKSKYKLLSLETDKNYFNNFIKITDSTTKI
                     IDTRNTKTYESGIFIDIFPIDRFDDPKVIDTCYKLESFKLLSFSKHKNIVYKDSLLKD
                     WIRTAFWLLLRPVSPRYFANKIEKEIQKYSRENGQYMAFIPSKFKEKEVFPSGTFDKT
                     IDLPFENLSLPAPEKFDTILTQFYGDYMTLPPEEKRFYSHEFHAYKLED"
     gene            8106..8915
                     /locus_tag="ACL29Z_000979"
     CDS             8106..8915
                     /locus_tag="ACL29Z_000979"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001199643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphorylcholine transferase LicD"
                     /protein_id="HGR0069309.1"
                     /translation="MQYLEKKEIKEIQLALLDYIDETCKKHDIPYFLSYGTMLGAIRH
                     KGMIPWDDDIDISLYREDYERLLKIIEEENHPRYKVLSYDTSSWYFHNFASILDTSTV
                     IEDHVKYKRHDTSLFIDVFPIDRFTDLSIVDKSYKYVALRQLAYIKKSRAVHGDSKLK
                     DFLRLCSWYALRFVNPRYFYKKIDQLVKNAVTNTPQYEGGVGIGKEGMKEIFPVDTFK
                     ELILTEFEGRMLPVPKKYDQFLTQMYGDYMTPPSKEMQEWYSHSIKAYRKS"
     gene            complement(9190..12366)
                     /gene="carB"
                     /locus_tag="ACL29Z_000980"
     CDS             complement(9190..12366)
                     /gene="carB"
                     /locus_tag="ACL29Z_000980"
                     /EC_number="6.3.5.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019803305.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0008152 - metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbamoyl-phosphate synthase large subunit"
                     /protein_id="HGR0069310.1"
                     /translation="MPKRTDIQKIMVIGSGPIIIGQAAEFDYAGTQACLSLKEEGYEV
                     VLVNSNPATIMTDKEIADKVYIEPITLEFVTRILRKERPDALLPTLGGQTGLNMAMEL
                     SKNGILDELGVELLGTKLSAIDQAEDRDLFKQLMEELEQPIPESEIVNTVEEAVTFAA
                     TIGYPVIVRPAFTLGGTGGGMCANEKELREITENGLKLSPVTQCLIERSIAGFKEIEY
                     EVMRDSADNALVVCNMENFDPVGIHTGDSIVFAPAQTMSDYENQMLRDASLSIIRALK
                     IEGGCNVQLALDPNSFKYYVIEVNPRVSRSSALASKATGYPIAKLAAKIAVGLTLDEV
                     INPVTGSTYAMFEPALDYVVAKIPRFPFDKFEKGERRLGTQMKATGEVMAIGRNIEES
                     LLKACRSLEIGVHHNEIPELAAVSDDALIEKVVKAQDDRLFYVSEAIRRGYTPEEIAE
                     LTKIDIFYLDKLLHIFEIEQELGAHPQDLEVLKTAKLNGFSDRKIAELWGTTDDQVRQ
                     LRLENKIVPVYKMVDTCAAEFDSETPYFYSTYGWENESIRSDKESVLVLGSGPIRIGQ
                     GVEFDYATVHSVKAIQAAGYEAIIMNSNPETVSTDFSVSDKLYFEPLTFEDVMNVIDL
                     EQPKGVIVQFGGQTAINLAEPLAKAGVTILGTQVADLDRAEDRDLFEQALKELDIPQP
                     PGQTATNEEEAALAARKIGFPVLVRPSYVLGGRAMEIVENEEDLRSYMRTAVKASPDH
                     PVLVDSYIVGQECEVDAISDGKNVLIPGIMEHIERAGVHSGDSMAVYPPQTLSQKVQE
                     TIADYTKRLAIGLHCLGMMNIQFVIKDEKVYVIEVNPRASRTVPFLSKVTNIPMAQVA
                     TKLILGQSLSELGYQNGLYPESTRVHIKAPVFSFTKLAKVDSLLGPEMKSTGEVMGSD
                     ATLEKALYKAFEASYLHLPTFGNVVFTIADDAKEEALNLARRFQNIGYGILATEGTAA
                     FFASHGLQAQPVGKIGDDDKDIPSFVRKGRIQAIINTVGTKRTADEDGEQIRRSAIEH
                     GVPLFTALDTANAMLKVLESRSFVTEAI"
     gene            complement(12679..13758)
                     /locus_tag="ACL29Z_000981"
     CDS             complement(12679..13758)
                     /locus_tag="ACL29Z_000981"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000166701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004088 - carbamoyl-phosphate synthase
                     (glutamine-hydrolyzing) activity [Evidence IEA];
                     GO_process: GO:0006541 - glutamine metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbamoyl phosphate synthase small subunit"
                     /protein_id="HGR0069311.1"
                     /translation="MTKRILVLEDGTVFEGKAFGADIDVTGEIVFNTGMTGYQESITD
                     QSYNGQILTFTYPLVGNYGINRDDYESIIPTCKGVVVFEEARRASNWRNQMTLDEFLK
                     AKKIPGISGIDTRALTKIIRKHGTMRATLTHVGDSMDHVTDQLQATVLPTDNIKQVST
                     KTSYPAPGVGLSVVLVDFGLKHSILRELSKRNCNVTVVPYSTTAEEILHLNPDGVMLS
                     NGPGNPEDVPQALDMIRGVQGKIPIFGICMGHQLFAMANGAKTYKMKFGHRGFNHAVR
                     EIATGRVDFTSQNHGYAVSREDLPEHLIITHEEINDKSVEGVRHRYQPAFSVQYHPDA
                     APGPHDASYLFDEFIEMMEVFKQSN"
     gene            complement(13808..14731)
                     /locus_tag="ACL29Z_000982"
     CDS             complement(13808..14731)
                     /locus_tag="ACL29Z_000982"
                     /EC_number="2.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001293822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004070 - aspartate carbamoyltransferase
                     activity [Evidence IEA];
                     GO_function: GO:0016597 - amino acid binding [Evidence
                     IEA];
                     GO_process: GO:0006207 - 'de novo' pyrimidine nucleobase
                     biosynthetic process [Evidence IEA];
                     GO_process: GO:0006520 - amino acid metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate carbamoyltransferase catalytic
                     subunit"
                     /protein_id="HGR0069312.1"
                     /translation="MSENQQALNHVVSMEDLTVDQVMKLIKRGIEFKNGAQLPYEDHP
                     IVSNLFFEDSTRTHKSFEVAEIKLGLERLDFDVKTSSVNKGETLYDTILTLSALGVDV
                     CVIRHPEVDYYRELIASPTITTSIINGGDGSGQHPSQSLLDLMTIYEEFGHFEGLKVA
                     IAGDLDHSRVAKSNMQILKRLGSELFFAGPEEWRSQEFADYGQFVTIDEIIDQVDVMM
                     FLRVQHERHDSGAVFSKEDYHAQHGLTQERYDRLKETAILMHPAPINRDVEIADHLVE
                     APKSRIVQQMTNGVFVRMAILESVLASRNAN"
     gene            complement(14750..15271)
                     /gene="pyrR"
                     /locus_tag="ACL29Z_000983"
     CDS             complement(14750..15271)
                     /gene="pyrR"
                     /locus_tag="ACL29Z_000983"
                     /EC_number="2.4.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000850024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional pyr operon transcriptional
                     regulator/uracil phosphoribosyltransferase PyrR"
                     /protein_id="HGR0069313.1"
                     /translation="MKTKEVVDELTVKRAITRITYEIIERNKDLNKIVLAGIKTRGVF
                     IAHRIQERLKQLENLSVPVVELDTKPFRDDVKSGEDTSLVSVDVTDREVILVDDVLYT
                     GRTIRAAIDNIVGHGRPARVSLAVLVDRGHRELPIRPDYVGKNIPTSRSEEIIVEMTE
                     LDDQDRVLITEEA"
     gene            complement(15482..16111)
                     /gene="nth"
                     /locus_tag="ACL29Z_000984"
     CDS             complement(15482..16111)
                     /gene="nth"
                     /locus_tag="ACL29Z_000984"
                     /EC_number="4.2.99.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000244461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0140078 - class I DNA-(apurinic or
                     apyrimidinic site) endonuclease activity [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease III"
                     /protein_id="HGR0069314.1"
                     /translation="MVLSKKRARKVLEEIIALFPDAKPSLDFTNHFELLVAVMLSAQT
                     TDAAVNKATPGLFVAFPTPQAMSVATESEIASHISRLGLYRNKAKFLKKCAQQLLDDF
                     DGQVPQTREELESLAGVGRKTANVVMSVGFGIPAFAVDTHVERICKHHDIVKKSATPL
                     EVEKRVMDILPPEQWLAAHQAMIYFGRAICHPKNPECDQYPQLYDFSNL"
     gene            complement(16111..16653)
                     /locus_tag="ACL29Z_000985"
     CDS             complement(16111..16653)
                     /locus_tag="ACL29Z_000985"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF177 domain-containing protein"
                     /protein_id="HGR0069315.1"
                     /translation="MKLNIQEIRKQSEGLNFEQTLDLVDDLRARNQEILDVKDILAVG
                     KVQYEDRMYFLDYQLSYTIVLASSRSMEPVELVESYPVTEVFMEGATNHLNQEILDDD
                     LVLPIENGALDLAESVSDNILLNIPIKVLTAEEEAGQGFVSGNDWQIMTEEEYQAQQA
                     VKKEENSPFAGLQGLFDGDE"
     gene            16823..17140
                     /locus_tag="ACL29Z_000986"
     CDS             16823..17140
                     /locus_tag="ACL29Z_000986"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000389556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helicase BlpT"
                     /protein_id="HGR0069316.1"
                     /translation="MEDKKLIQLLSKLNKSYQNCKQGTADDIRLQELLNTTMQELKKT
                     EQLNNSILIDLEKFYQPTSPLIGLGSLKLNNQARTAWRNYDKIHYEHVKHVLSLYGPV
                     FGF"
     gene            17379..18938
                     /locus_tag="ACL29Z_000987"
     CDS             17379..18938
                     /locus_tag="ACL29Z_000987"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011681787.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HGR0069317.1"
                     /translation="MHYEHSRKGNHMIKINHLTITQNKDLRDLVSDLTMTIQDGEKVA
                     IIGEEGNGKSTLLKILMGEALSDFTIKGNIQSDYQSLAYIPQKLPEELKKKTLHDYFF
                     LDSIDLDYSILYRLAEELHFDSNRFASDQEIGNLSGGEALKIQLIHELAKPFEILFLD
                     EPSNDLDLETVDWLKGQIQKTRQTVIFISHDEDFLSETADTIVHLRLVKHRKEAETLV
                     EHLDYDSYSEQRKANFAKQSQQAANNQRAYDKTMEKHRRVKQNVETALRATKDSTAGR
                     LLSKKMKTVLSQEKRYEKAAQSMTQKPLEEEQIQLFFSDIQPLPASKVLVQLEKENLS
                     IDDRVLVQKLQLTVRGQEKIGIIGPNGVGKSTLLAKLKQLLNDKREISLGFMPQDYHK
                     KLQLDLSPIAYISKTGEKEELQKIHSHLASLNFSYPEMQHQIRSLSGGQQGKLLLLDL
                     VLRKPNFLLLDEPTRNFSPTSQPQIRKLFATYPGGLITVSHDRRFLKEVCSIIYRMTE
                     HGLELVNLEDL"
     gene            complement(18982..19881)
                     /gene="htpX"
                     /locus_tag="ACL29Z_000988"
     CDS             complement(18982..19881)
                     /gene="htpX"
                     /locus_tag="ACL29Z_000988"
                     /EC_number="3.4.24.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000895736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004222 - metalloendopeptidase activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="zinc metalloprotease HtpX"
                     /protein_id="HGR0069318.1"
                     /translation="MLFDQIASNKRKTWILLLVFFLLLALVGYAVGYLFIRSGLGGLV
                     IALIIGFIYALSMIFQSTEIVMSMNGAREVDEQTAPDLYHVVEDMALVAQIPMPRVFI
                     IDDPALNAFATGSNPQNAAVAATSGLLAIMNREELEAVMGHEVSHIRNYDIRISTIAV
                     ALASAITMLSGMAGRMMWWGGAGRRRSDDDRDGNGLEIIMLVVSLLAIVLAPLAATLV
                     QLAISRQREFLADASSVELTRNPQGMINALDKLDNSKPMSRHVDDASSALYINDPKKG
                     GGFQKLFYTHPPISERIERLKQM"
     gene            complement(19883..20443)
                     /locus_tag="ACL29Z_000989"
     CDS             complement(19883..20443)
                     /locus_tag="ACL29Z_000989"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000219838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LemA family protein"
                     /protein_id="HGR0069319.1"
                     /translation="MTWIILGVLALVVIFVIVSYNGLVKNRMQTKEAWSQIDVQLKRR
                     NDLLPNLIETVKGYAKYEGSTLEKVAELRNQVAAATSPAEAMKASDALTRQVSGIFAV
                     AESYPDLKASANFVKLQEELTNTENKISYSRQLYNSVVSNYNVKLETFPSNIIAGMFG
                     FKAADFLQTPEEEKSVPKVDFSGLGD"
     gene            20537..21250
                     /gene="rsmG"
                     /locus_tag="ACL29Z_000990"
     CDS             20537..21250
                     /gene="rsmG"
                     /locus_tag="ACL29Z_000990"
                     /EC_number="2.1.1.170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005575 - cellular_component [Evidence
                     IEA];
                     GO_function: GO:0008168 - methyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0031167 - rRNA methylation [Evidence IEA];
                     GO_process: GO:0046118 - 7-methylguanosine biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (guanine(527)-N(7))-methyltransferase
                     RsmG"
                     /protein_id="HGR0069320.1"
                     /translation="MKPKTFYNLLAEQNLPLSDQQKEQFERYFELLVEWNEKINLTAI
                     TDKEEVYLKHFYDSIAPILQGLIPNETIKLLDIGAGAGFPSLPMKILYPELDVTIIDS
                     LNKRINFLQLLAQELDLNGVHFYHGRAEDFAQDKNFRAQYDFVTARAVARMQVLSELT
                     IPYLKVGGKLLALKASNAPEELLEAKNALNLLFSKVEDNLSYALPNRDPRYITVVEKK
                     KETPNKYPRKAGMPNKRPL"
     gene            21553..22836
                     /locus_tag="ACL29Z_000991"
     CDS             21553..22836
                     /locus_tag="ACL29Z_000991"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007554578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="solute carrier family 23 protein"
                     /protein_id="HGR0069321.1"
                     /translation="MKQESTVDLLLDVDQRPSDGKGILLSFQHVFAMFGATILVPLIL
                     GMPVSVALFASGVGTLIYMIATGFKVPVYLGSSFAFITAMSLAMKEMGGDVSAAQTGV
                     ILTGLVYVLVATSIRFVGTKWIDKLLPPIIIGPMIIVIGLGLAGSAVTNAGLVADGNW
                     KNALVAVVTFLIAAFINTKGKGFLRIIPFLFAIIGGYLFALTLGLVDFTPVLKANWFE
                     IPGFYLPFSTGGAFKEYNLYFGPEAIAILPIAIVTISEHIGDHTVLGQICGRQFLKEP
                     GLHRTLLGDGIATSVSAFLGGPANTTYGENTGVIGMTRIASVSVIRNAAFIAIALSFL
                     GKFTALISTIPNAVLGGMSILLYGVIASNGLKVLIKERVDFAQMRNLIIASAMLVLGL
                     GGAILKLGPVTLSGTALSAMTGIILNLILPYENKD"
     gene            complement(23031..24602)
                     /gene="ffh"
                     /locus_tag="ACL29Z_000992"
     CDS             complement(23031..24602)
                     /gene="ffh"
                     /locus_tag="ACL29Z_000992"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002902912.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0048501 - signal recognition particle,
                     plasma membrane targeting [Evidence IEA];
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005048 - signal sequence binding
                     [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_process: GO:0009306 - protein secretion [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="signal recognition particle protein"
                     /protein_id="HGR0069322.1"
                     /translation="MAFESLTERLQNVFKNLRKKGKISESDVQEATKEIRLALLEADV
                     ALPVVKDFIKKVRERAVGHEVIDTLNPAQQIIKIVDEELTAVLGSDTAEIIKSPKIPT
                     IIMMVGLQGAGKTTFAGKLANKLKKEENARPLMIAADIYRPAAIDQLKTLGQQIDVPV
                     FALGTEVPAVEIVRQGLEQAQTNHNDYVLIDTAGRLQIDELLMNELRDVKALAQPNEI
                     LLVVDAMIGQEAANVAREFNAQLEVTGVILTKIDGDTRGGAALSVRHITGKPIKFTGT
                     GEKITDIETFHPDRMSSRILGMGDMLTLIEKASQEYDEQKALEMAEKMRENTFDFNDF
                     IDQLDQVQNMGPMEDLLKMIPGMANNPALQNMKVDERQIARKRAIVSSMTPEERENPD
                     LLNPSRRRRIAAGSGNTFVEVNKFIKDFNQAKQLMQGVMSGDMNKMMKQMGINPNNLP
                     KNMPNMGGMDMSALEGMMGQGGMPDLSALGGAGMPDMSQMFGGGLKGKIGEFAMKQSM
                     KRMANKMKKAKKKRK"
     gene            complement(24614..24946)
                     /locus_tag="ACL29Z_000993"
     CDS             complement(24614..24946)
                     /locus_tag="ACL29Z_000993"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014637934.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative DNA-binding protein"
                     /protein_id="HGR0069323.1"
                     /translation="MEIEKTNRMNALFEFYAALLTDKQMNYIELYYADDYSLAEIAEE
                     FGVSRQAVYDNIKRTEKILEDYEMKLHMYSDYIVRSQIFDQILERYPKDNFLQEQIEI
                     LTSIDNRE"
     gene            complement(25037..25414)
                     /locus_tag="ACL29Z_000994"
     CDS             complement(25037..25414)
                     /locus_tag="ACL29Z_000994"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000701643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1934 domain-containing protein"
                     /protein_id="HGR0069324.1"
                     /translation="MKIRMRNTIQFDEQLEVIDQLYDVEVHEKGDYSYLLFYNEEKEK
                     VVIKFHGQELVMSRFSNPKTIMRFLKDSDSLAYIPTPMGMQEFIIQTNRYQVDGQKIE
                     LDYQLQNQEGHPFASYQLEITWG"
     gene            25486..26790
                     /locus_tag="ACL29Z_000995"
     CDS             25486..26790
                     /locus_tag="ACL29Z_000995"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001003495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042578 - phosphoric ester hydrolase
                     activity [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HGR0069325.1"
                     /translation="MNEKVFRDPVHNYIHVNNQIIYDLINTKEFQRLRRIKQLGTSSY
                     TFHGGEHSRFSHCLGVYEIARRITEIFEEKYPEEWNPAESLLTMTAALLHDLGHGAYS
                     HTFENLFDTDHEAITQEIIQNPETEIHQVLLQVAPDFPEKVASVIDHTYPNKQVVQLI
                     SSQIDADRMDYLLRDSYFTGASYGEFDLTRILRVIRPIENGIAFQRNGMHAIEDYVLS
                     RYQMYMQVYFHPATRAMEVLLQNLLKRAKELYPEDKDFFARTSPHLLPFFEKNVTLTD
                     YLALDDGVMNTYFQLWMTSPDKILADLSHRFVNRKVFKSITFSQEDQDQLASMRKLVE
                     DIGFDPDYYTAIHKNFDLPYDIYRPESENPRTQIEILQKNGELAELSSLSPIVQSLAG
                     SRHGDNRFYFPKEMLDQNSIFASITQQFLYLIENDHFTPNKN"
     gene            26803..27609
                     /gene="yidA"
                     /locus_tag="ACL29Z_000996"
     CDS             26803..27609
                     /gene="yidA"
                     /locus_tag="ACL29Z_000996"
                     /EC_number="3.1.3.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000023490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sugar-phosphatase"
                     /protein_id="HGR0069326.1"
                     /translation="MSIKLIAVDIDGTLVNSQKEITPEVFSAIQDAKEAGVKVVIATG
                     RPIAGVAKLLDDFQLRDQGDYVVTFNGALVQETATGHEIISESLTYEDYLDMEFLSRK
                     LGVHMHAITKDGIYTANRNIGKYTVHESTLVSMPIFYRTPEEMAGKEIVKCMFIDEPE
                     ILDAAIEKIPAEFYEHYSINKSAPFYLELLKKNVDKGSAITHLAEKLGLTKDETMAIG
                     DEENDRAMLEVVGNPVVMENGNPEIKKIAKYITKSNDESGVAHAIRTWVL"
     gene            complement(27664..27735)
                     /locus_tag="ACL29Z_000997"
     tRNA            complement(27664..27735)
                     /locus_tag="ACL29Z_000997"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(27700..27702),aa:Arg,seq:cct)
     gene            complement(27777..28124)
                     /gene="rplS"
                     /locus_tag="ACL29Z_000998"
     CDS             complement(27777..28124)
                     /gene="rplS"
                     /locus_tag="ACL29Z_000998"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005590628.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0000311 - plastid large ribosomal subunit
                     [Evidence IEA];
                     GO_component: GO:0022625 - cytosolic large ribosomal
                     subunit [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L19"
                     /protein_id="HGR0069327.1"
                     /translation="MNPLIQSLTEGQLRTDIPSFRPGDTVRVHAKVVEGNRERIQIFE
                     GVVIARKGAGISENYTVRKISNGVGVERIFPIHTPRVEKIEVVRYGKVRRAKLYYLRA
                     LQGKAARIKEIRR"
     gene            complement(28243..28572)
                     /gene="crcB"
                     /locus_tag="ACL29Z_000999"
     CDS             complement(28243..28572)
                     /gene="crcB"
                     /locus_tag="ACL29Z_000999"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000237393.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fluoride efflux transporter CrcB"
                     /protein_id="HGR0069328.1"
                     /translation="MVIVYLAIACGLGALVRYFFSRYNQASKLPLGTLIANLLGCFLI
                     GVFYNHVESKEVYAILATGFCGGLTTFSTLNDELQRLLSDKKVFYSYLTLTYIGGLVA
                     IFLGILL"
     gene            complement(28566..28940)
                     /gene="crcB"
                     /locus_tag="ACL29Z_001000"
     CDS             complement(28566..28940)
                     /gene="crcB"
                     /locus_tag="ACL29Z_001000"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000712114.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fluoride efflux transporter CrcB"
                     /protein_id="HGR0069329.1"
                     /translation="MKKEQFYPLGIFIAAMLGGLIRYLVSIWLPASPDFPWGTLLVNY
                     LGIFCLIYLVKGYLVYKGTSKGLILALGTGFCGGLTTFSSLMLDAVKLLDTGRYLSLI
                     LYLLLSIGGGLLLAYYLGRKKW"
     gene            complement(28937..29203)
                     /locus_tag="ACL29Z_001001"
     CDS             complement(28937..29203)
                     /locus_tag="ACL29Z_001001"
                     /EC_number="5.4.99.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398165.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chorismate mutase"
                     /protein_id="HGR0069330.1"
                     /translation="MDLDIIRQEIDQIDDQIVKLLEERMHLVEGVVAYKKASGKPILD
                     TKREEVIFEKVGSRVEDKRYQETIVATFSDILKRSRDYQDQNIK"
     gene            complement(29319..29762)
                     /locus_tag="ACL29Z_001002"
     CDS             complement(29319..29762)
                     /locus_tag="ACL29Z_001002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016465724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin"
                     /protein_id="HGR0069331.1"
                     /translation="MALAKIVFASMTGNTEEIADIVADKLRDLGLDVDVDECTTVDAS
                     DFLEADIAIVATYTYGDGELPDEMMDFYEDLADLNLNGKIYGVVGSGDTFYDEFCKAV
                     DDFDRVFVSTGAEKGSECVKVDLSAEEEDIERLEQFVEELAAKVG"
     gene            29866..30801
                     /locus_tag="ACL29Z_001003"
     CDS             29866..30801
                     /locus_tag="ACL29Z_001003"
                     /EC_number="3.1.3.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0004527 - exonuclease activity [Evidence
                     IEA];
                     GO_function: GO:0008441 - 3'(2'),5'-bisphosphate
                     nucleotidase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional oligoribonuclease/PAP phosphatase
                     NrnA"
                     /protein_id="HGR0069332.1"
                     /translation="MEICQQILEKIKEYDTIIIHRHMKPDPDALGSQVGLKALLEHHF
                     PEKTIKAVGFDEPTLTWMAEMDLVEDRAYQGALVIVCDTANTARIDDKRYSQGDFLIK
                     IDHHPNDDVYGDLSWVDTSSSSASEMITLFAQTTQLALADRDAELLFAGIVGDTGRFL
                     YPSTTARTLRLAAYLREHNFDFAALTRKMDTMSYKIAKLQGYIYDHLEVDENGAARVI
                     LSQEVLKQYNVTDAETAAIVGAPGRIDRVSLWGIFVEQADGHYRVRLRSKIHPINEIA
                     KEHDGGGHPLASGANSYSLEENEIIYQKLKNLLKN"
     gene            30897..31139
                     /locus_tag="ACL29Z_001004"
     CDS             30897..31139
                     /locus_tag="ACL29Z_001004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019770973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type B 50S ribosomal protein L31"
                     /protein_id="HGR0069333.1"
                     /translation="MKKDIHPEYRPVVFMDTTTGYQFLSGSTKRSNETVEFEGETYPL
                     IRVEISSDSHPFYTGRQKFTQADGRVDRFNKKYGLK"
     gene            complement(31196..31774)
                     /locus_tag="ACL29Z_001005"
     CDS             complement(31196..31774)
                     /locus_tag="ACL29Z_001005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866395.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron permease"
                     /protein_id="HGR0069334.1"
                     /translation="MVRNYWKAKSWLLVLALSFLILSPAGAQESLSFFFVKITDASKA
                     VKNGGQTETQKLVTKMASDFERVENKDSEVGKIVKEKLALSGDITEAKLTEISSALLA
                     FEKEQNPVDLDAEKEKLVNRLSPRFETLEQAIASKDLEKVREAFKKMNSTWTINESMV
                     RDNSTAHYGRVETAISFLPSSMETEPTDESGT"
     gene            complement(31749..32760)
                     /locus_tag="ACL29Z_001006"
                     /pseudo
     CDS             complement(31749..32760)
                     /locus_tag="ACL29Z_001006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004259617.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing N-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology.
                     GO_function: GO:0004601 - peroxidase activity [Evidence
                     IEA];
                     GO_function: GO:0020037 - heme binding [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="Dyp-type peroxidase"
     gene            complement(32763..32910)
                     /locus_tag="ACL29Z_001007"
                     /pseudo
     CDS             complement(32763..32910)
                     /locus_tag="ACL29Z_001007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611577.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus and C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS630 family transposase"
BASE COUNT         9863 a         7185 c         6074 g         9788 t
ORIGIN      
        1 attcactata ctttccctta tactcaatga aaatcaaagc gcaaactagg aagctagcca
       61 caggttgctc aaagcactgc tttgaggttg tagataagac tgacgaagtc agctcaaaat
      121 actgttttga ggttgcagat ggaagctgac gtagtttgaa gagattttcg aagagtatta
      181 tatgagaaaa atcctctact ctactaatcc acttagaaaa aacgcatatt atcaagtgtt
      241 aaaaacttgc taatatgcgt tttattatgg aaatgttggg ttcattttct cttaaaattg
      301 attttttctt agaattctag cttaggtcat ttttaaaatt caaattccgc aagaacatct
      361 tgcccactgg tgaccaattt tgctccttct tgaatcaaat gatggcaacc gtctgatagt
      421 ccatctaaaa tgctatcagg aatagcaaag acatcgcgtc cttcttccat tgctcgctca
      481 cacgtaatga gactacctga acgcatctta gcctctgcta caatcacacc acgacaaagt
      541 ccagcaatga tgcgattacg ggcaggaaaa tgaaatttca gaggttgttc gccaggtcca
      601 tattcactta gaaccagatg gtcattgccg atgtagtctt gcaagcgttt attggcttta
      661 ggataaaaca catccagtcc tgttccaatc actgcaatgg tttttccgcc attctgaaga
      721 gctgccatat gagctgctgt gtcaatgccc ttggccagac cactgacaat aaccagttca
      781 ttttccaagc cttgaatgac tttttcaact gtcttagctc cctgtttgct acaagcacga
      841 ctgcccacga ccgctacctt cgggaatttc aggaggtcaa gatttccctt gtaaaataaa
      901 agtacaggcg catcatatat ttcactcaaa tcccaaggat aacagtcatc taaaatagag
      961 aaagatggaa atttttgaaa ctctttcgac aaatgcgcat cgtctatctg aaaataacgt
     1021 tccataaaaa cggctggatt acggcaacct gatatatctg caatatcacc caacaaaagc
     1081 tcctgatcaa cattttcacc gtattctagc actttcaaaa tctgttgatt ggtcaaactt
     1141 gattttttta acttatagat ttcatagttt gtgattttca taaataactc catttctttt
     1201 tctactcatc tatctattcg taaaagttcg taaaaaatca aaaaaacatc cgactatttt
     1261 gtcagatgtt ggaagctttt aattttcgtt tttaagaatt tcttctaatt tatgatagtc
     1321 ttggacacta tcaatctcat aaatgctatt gccttctaat tcttcaacat agacatctag
     1381 ctctttgatg ttatccttaa ccatattgtc ccaatagaga tcaacaaatt cgccgcttgc
     1441 ataagcctta tcgataaagc taacaatttt ttctgctgtt ggagcatccc agaaggatac
     1501 accactaagg atgcgacctg ccttgctatc aacaataatg ttttgaacct tgtagtcatc
     1561 tccatagacc aagaaccatt cgttggtaca atcttcacga tagacactaa aataagtcga
     1621 acgtgtcaaa tcattgcgga acatattttt aaagagatag ttatcggcat cgataacata
     1681 actattggct aattcttctt ttacaagata gagagagtaa aagttattgt agtcagcgta
     1741 tttatcattg aaaacgagac gaacaccgta tttctctttc aagtaatcga attgttcttt
     1801 aagataacca acaatgatga tgatgtcatt gattcctttt tctttgagaa actcaatttg
     1861 gtactcaatc aaaggttttt gattaacctg aaccaaggct ttaggggtat tttcagtcat
     1921 aggacgcaag cgagttccca atcccgctgc taagatgatg gctttcacac gaatctcctt
     1981 tattctttaa taataatata aactccagca atgacgacaa gtgacgtcat aattgtcagc
     2041 atatctagcg gtgcacccaa gaaaacaact gcaaacaaga ccgtccatac tacatagctc
     2101 acgttcaagc ctgtagcctt ggctggttgc aagcgattga tagcgatata ataagccaag
     2161 taggaaatca tatcaaaggc tgcaaaaaca atcatgagac ctagcaattg tccattggct
     2221 actgcagtaa atgactgatg agagaagagc acaatcacaa gataggacaa gaacgaagtc
     2281 acttgacgga ttaagagggc ttcgatttca ctcagttcac tttccatagc aaaggagcta
     2341 agaacactct cacttcccca tgcaatagca caaaccaaag cacagagaat cccaatgtag
     2401 aaggaattaa cctgttcaac tttataggtc tgggcaataa tccctccaat aatcaagaca
     2461 attccaaata cagtattttt cgaaatcttg tgcttcaaaa agaagaaagc caatagaact
     2521 gaaatcgcag ggtaaatagc cgatacagat gaagctaaag aacttccgat atacttaact
     2581 gcataaagat tggcctgcat accgataggg cctgctagca aggctccgat gataacactg
     2641 acattgcgaa tatttaagaa aattgagagg cgaactttcc cttcttttac caagagaaaa
     2701 gctagtaaga taaagatgct caaaaaatca tgagctgcag ccaccacaaa gggtgacaaa
     2761 tctgtaaaaa tcgaaaagat ataagcacta accgttagac ccaagcccca gaaaatacct
     2821 gagagaaggc caaaaggaac tccgttttta cttttcatct gaacctccat aagaagccaa
     2881 acctttaaca gctctttggt aacgattcac accatagtca ccaaaatctt caccttgctc
     2941 ttccttatag acagtccata gactccaaat agtatcttgt aaaattttat aaatagcaat
     3001 cttttcatga gaaaccggtg tttggtcact ctcatagtga gataagaaag tttcttcctc
     3061 ttgggaagtg aattcagact ctaaaaagag ggcagccaaa tcccacattg gatcattcat
     3121 tgatgaatat tcccagtcaa tcaaataaag tcgtccttga ggtgattcga taaagttttc
     3181 aggcaccaaa tcgatatgac aagattttct gtcaacacct aagtcagcca gtcttttctc
     3241 taaggagaag actgcatttc taacagattc atagttggca taaggaattt gttcttcaat
     3301 caaggattcg tattttttga tttcttcaaa aggagcaaat tctcctctta attccttagc
     3361 agacgtatga atagtttgta atattggagc aattttgtcg aacttggtct tgattgacgt
     3421 tgaatcaagc gtaatcgcag attcgatata ctcatttact ttgataccag cttcaatatc
     3481 aaaaagataa ttttttacat ctaagcctaa atcctttagt agttcaagat tgtacttttc
     3541 atcttgtcga ttaataagct tttctgtccc tttaccaaag aatttaacaa tgtattgctt
     3601 atttgttgtt ttggccaaat agttttgatt ggtcattcca cccagttgtt caacactgag
     3661 gacttcctct tcttgactaa gtaaggaaga aattttttct ttaatgattt tctccacaat
     3721 taacctccag tacttatact tcccacttaa acactgtttt aaaggctgtg tttaaatcgg
     3781 ttgcaaagac acgatgaata tctttaattt ctcttacagg ttcttctaga taaaggatat
     3841 ttttaagacg attggcaaat ttcttgactt ccatcatttg gatagcattt tcaaaatcaa
     3901 tgcgaccaga acgagatgac ccaaccaaaa tcaagccctt ttctaaggca tcgcgagtat
     3961 tgagattgac tttatattcg ctaactccca tcatgagaat cgttccctga ggacgaatgt
     4021 agcgaatcaa gtcattaata gctggtccag taccatcacc accacaacat tcaaaagcat
     4081 ggtcaaaggc caaatcttca ggaatattat ccgtaatata gcattctttg gcaaatgaga
     4141 agagttccaa cttttcccaa tgacgaccaa taaccacaat ctctgattct ggcaaagtat
     4201 agttgataat attggcaacc acaaaagcta aacttccatc tccaataacg gcgatccgct
     4261 cccgcttgct atgagcaaga gtcaatagac gattcatagc gtgcatgccc acactgacaa
     4321 actctgtaat ggctgcaacc gtatcttcaa tagcatcata agccaccaca cgatctttag
     4381 ggagagaaac aaactctctc ataaagccat caaatccact agacaagaaa tgggtccctg
     4441 tcatgtagtt ttcatagaat tcttcatcac tctgcatagg agactgattg ggaatcatga
     4501 caactttttg accaacctcg taggttccgg tcgggtcaga aatgacggtt ccacatgact
     4561 cgtgaatcat tgccattgga agctttttat tcaaaatctt gggatcacgt tttccctgat
     4621 agtaacgctg atccgcatga cagacagcca tgtagttggg acggataagg atatgattct
     4681 cttggtcaat agcctcttcc tgatatttga cattgataaa cttaggctta gttagttgat
     4741 aaatttgatt aatcatttta ctagtctttc tcaatcatac tttttgcaat cttcaaatct
     4801 gttacggttg taatcttcag atttgagtat tcacctttgg ccaaggccac atcttttcct
     4861 ttgatcacaa agattttaca tgcatctgtc aagatttcct tctcttcatc agaaagagat
     4921 ccataaaggt ccatgaagtc cttgcaacgg aatgtttgag gtgtttgtcc ttgataaagg
     4981 tgagcacgat ttggaatatc tgtaataaat tgaccattgg tactttcaac gatagtatca
     5041 accgcttcta ccactgtgtc cactgcgtca tgattttggg caagttggat attgtcctga
     5101 atcatgcgaa gtgtaataaa tggacgaaca gaatcgtggg taacaacgat atcctctgga
     5161 gtaagcggac gataagcatc aatggcttca atgattttct taatacttgt attgcggtca
     5221 gcaccaccct ttgtaatgat gatacgttcc ttataaagag gaagatattt atctacaaga
     5281 tcttctgcat gagaaaccca gtctccatga acaccaacta caattttttc aatacttgac
     5341 tccaagacaa atttttcaat tgtatgaatc aaaataggtc gatcacctag ctctaaaaat
     5401 tgttttggca agttactgat ccccatgcgt gtgccagttc caccggcaag aattcctgca
     5461 taaatcatct attttctcct ttgtcttact aaaaaaactt attctctcta ttataccaca
     5521 atctagtcct atcataaaag aaatactggt cctccccttc tagaatagga gaattatgca
     5581 gttctattat tcaaagaaac tagtccattt ctagtaatga ctaggaattc tgtagcaatt
     5641 actaataaat ggctgcgaaa ttttagagtc cttcagaata atatactttc cttaaagaaa
     5701 acttaaaact taagatttga aacttcaaag tgattacttg acttactgcc cttcatttct
     5761 tattagctaa ctttatgata taatgaaaaa cgaggtaaat tgaatgaaaa gtataaaatt
     5821 aaatgctcta tcttacatgg gaattcgtgt cttgaacatt atttttccca tcctaactgg
     5881 aacctatgtc gcgcgtgtct tggaccgaac tgactatggt tacttcaact cagtcgacac
     5941 tattttgtca tttttcttgc cctttgcaac ttatggtgtc tataactacg gtttaagggc
     6001 tatcagtaat gtcaaggata acaaaaaaga tcttaacaga accttttcta gtctttttta
     6061 tttgtgcatc gcttgtacga ttttgaccac tgctgtctat atcctagcct atcctctctt
     6121 ctttactgat aatccaatcg tcaaaaaggt ctaccttgtt atggggattc aactcattgc
     6181 ccagattttt tcaatcgaat gggtcaatga agctctggaa aattacagtt ttctctttta
     6241 caaaactgcc ttcatccgta tcctgatgct ggtctctatt ttcttatttg ttaaaaatga
     6301 acacgatatt gttgtctata cacttgtgat gagtttatcg acgctgatta actacctgat
     6361 tagttatttt tggattaaaa gagacatcaa acttgttaag attcacctaa gtgattttaa
     6421 accactcttt ctccctctga cagccatgtt agtctttgcc aatgccaata tgctcttcac
     6481 ttttttagat cgcctcttcc tcgttaaaac agggattgat gtcaacgtta gttactatac
     6541 catagctcag cgaattgtga ccgttatagc tggggttgta acaggtgcaa ttggagtgag
     6601 tgtgcctcgt ctcagttact atctggggaa aggagacaaa gaagcctatg tttctctggt
     6661 taatagaggt agtcgaatct ttaacttctt tatcattcca ctgagttttg gactcatggt
     6721 tttaggacca aatgccatcc tactttacgg tagtgaaaaa tatatcggag gcggcatctt
     6781 gacctctctc ttcgcttttc gtacgattat tctggcctta gataccattc ttggttccca
     6841 aattctcttt accaatggct atgaaaaacg tatcacagtc tatacagtct ttgctgggct
     6901 actcaatttg ggcttgaata gtctcctctt tttcaaccat atcgtggttc ctgaatacta
     6961 cttactgaca actatgttat cagagacttc tctacttgtt ttctatatta ttttcatcca
     7021 tagaaaacaa ctcatccact tgggacatat ctttagctat actgttcgat actctctctt
     7081 ttcactttcc tttgtagcaa tttatttcct gattaatttc atgtatcctg tggatatggt
     7141 cattaatttg ccatttttga ttaatactgg tttgattgtc ttgctatcag ctatctctta
     7201 tattagtcta cttgtcttca caaaagatag cattttctat gaatttttaa accatgtcct
     7261 agccttaaaa aataaattta aaaaatcata ggagtttaaa atgaaacaac taaccgttga
     7321 agatgccaaa caaattgaat tagaaatttt ggattatatt gatactctct gtaaaaagca
     7381 caatatcaac tatattatta actacggtac tctgattggg gcggttcgac atgagggctt
     7441 tatcccttgg gacgacgata ttgatctgtc catgcctaga gaagactacc aacgatttat
     7501 taacattttt caaaaggaaa aaagcaagta taagctccta tccttagaaa ctgataagaa
     7561 ctactttaac aactttatca agataaccga cagtacgact aaaattattg atactcgaaa
     7621 tacaaaaacc tatgagtctg gtatctttat cgatattttc cctatagatc gctttgatga
     7681 tcctaaggtc attgatactt gttataaact ggaaagcttc aaactgctgt ctttcagtaa
     7741 acataaaaat attgtctata aggatagcct tttaaaagat tggatacgaa cagccttttg
     7801 gttgctcctt cgaccagttt ctcctcgtta ttttgcaaat aaaatcgaga aagaaattca
     7861 aaaatatagt cgtgaaaatg ggcagtatat ggcttttatc ccttcaaaat ttaaggaaaa
     7921 ggaagtcttc ccaagtggta cctttgataa aacaatcgat ttaccctttg agaatttaag
     7981 ccttcctgca cctgaaaaat ttgatactat tttgacacaa ttttatggag attatatgac
     8041 cctaccacca gaagaaaaac gcttctacag tcatgaattt cacgcttata aattggagga
     8101 ttaggatgca atatttagaa aaaaaagaaa ttaaagaaat tcaactagcc ctgctggact
     8161 atattgatga gacttgtaag aaacatgata ttccttattt tctcagttat ggaaccatgc
     8221 ttggagccat ccgccacaaa ggtatgattc cttgggatga tgatattgat atttcccttt
     8281 atcgtgagga ttatgagcgt ttactgaaga ttattgaaga agaaaatcac cctcgctaca
     8341 aggttctttc ctacgataca tcttcttggt acttccataa tttcgcatcg attttggaca
     8401 cttctactgt tatagaagac catgttaagt acaagcgtca tgataccagc cttttcatcg
     8461 atgtcttccc aattgatcga tttacagact tgagcattgt cgacaagagc tataagtatg
     8521 tggctcttcg tcaactagct tatatcaaaa aatcacgagc agttcacggt gatagcaaac
     8581 taaaagattt tcttagatta tgtagctggt acgctctccg atttgtcaat cctcgctact
     8641 tttacaagaa aattgatcaa ctagtcaaaa atgctgtaac caacactcct caatatgaag
     8701 gaggagttgg gatcggtaag gaagggatga aagaaatctt cccagttgat acctttaaag
     8761 aactgatttt aactgagttt gagggccgta tgttgcctgt tcccaaaaaa tatgaccaat
     8821 ttttaaccca gatgtatggc gattatatga caccaccatc aaaagaaatg caagaatggt
     8881 atagtcatag tattaaagct tatcgtaaaa gctgattgag ggggattata caaactacta
     8941 agatagaggt tattcaaaaa cataatttta gtagaaaatg aaatacatat tcccacaata
     9001 aaacgcatca tatcaaggtt tttgaaaaac cttgatatga tgcgttttat aattttaaag
     9061 acttttttct atagtagatt gaaataagat gcgaacgaat caattagaaa attcaaatta
     9121 atttctagaa atattttagt atccctgtgt actgttctaa attcagtttg ctatatctta
     9181 tttttctatt taaatcgctt ctgtaacaaa gctacgactt tcaagtacct taagcatagc
     9241 attagctgta tctagcgctg tgaagagggg caccccgtgt tcaatggctg aacgacgaat
     9301 ttgctcacca tcttcgtcag cagttcgttt tgttcctact gtgttaatga tagcttgaat
     9361 tcttcctttg cgtacaaaac ttgggatatc cttatcgtca tcaccaatct taccaacagg
     9421 ttgggcttgc aagccatgac tagcaaagaa ggctgctgtc ccttctgtcg caaggattcc
     9481 ataaccaatg ttttggaaac gacgagccaa gttcaaggct tcttctttgg catcatcagc
     9541 gatggtaaag acgacattac caaaagttgg caagtgtaga taagaagctt caaaggcttt
     9601 atagagagct ttttccaaag tagcatcaga acccataact tcacctgttg acttcatttc
     9661 aggaccgagc aagctgtcta ccttagctag tttggtaaag gagaagacag gtgccttgat
     9721 atgaacacgg gtgctttcag ggtaaagtcc attttggtag ccaagttctg ataaactttg
     9781 accaagaatg agcttggtcg ctacttgagc cataggaata ttggttacct tagataggaa
     9841 tggaacggta cggctggcac gtggattgac ctcaataacg tagacttttt catccttgat
     9901 aacaaactgg atgttcatca ttccaaggca gtgaagaccg attgctaagc gtttggtgta
     9961 gtctgcgatg gtctcctgaa ccttttgcga caaggtttgt ggtgggtaaa cagccattga
    10021 gtcacctgag tggacaccag cacgttcgat atgctccatg ataccaggaa tgagtacatt
    10081 tttaccatct gaaatggcat caacttcgca ctcttgccca acgatataag agtcgacaag
    10141 aactgggtgg tctggactag ccttaacagc agttcgcatg taagaacgaa ggtcttcttc
    10201 gttttcaacg atttccatgg cacgtccacc aagtacataa gatgggcgga caagaactgg
    10261 gaagccaatc ttacgagctg caagagctgc ttcttcttca ttggtagccg tttgtcctgg
    10321 tggctgtgga atatccaatt ctttgagagc ttgctcgaag aggtcacggt cttcggcacg
    10381 gtctaggtca gcaacctgtg taccaaggat ggtcacacct gcttttgcca atggctccgc
    10441 aaggttgatg gctgtttgac caccgaactg aacgataact ccctttggtt gttccaagtc
    10501 aatgacgttc ataacatctt cgaatgtcaa tggctcaaag taaagcttat ctgatacaga
    10561 gaagtctgtt gaaacggtct ctgggtttga gttcatgatg atagcttcat aaccagctgc
    10621 ctggatagcc ttaacagagt gaacggttgc gtagtcaaac tcaacccctt gaccgatacg
    10681 gattggacct gaacctagga caagtacaga ttctttatca gatctgatag attcattttc
    10741 ccaaccatag gttgaataga aatatggcgt ttcagagtcg aactctgccg cacaagtatc
    10801 taccatctta taaactggaa caatcttgtt ttccaagcga agttggcgaa cttgatcatc
    10861 agtcgttccc cagagttcag caatcttacg gtctgagaaa ccattaagtt tggctgtttt
    10921 caaaacttct agatcttgtg gatgagcacc caattcttgc tcaatttcaa agatatgcaa
    10981 gagtttatca agatagaaga tatcaatttt tgtaagctct gcaatttctt caggtgtgta
    11041 gccacgacga attgcttctg atacgtagaa gagacggtca tcttgggctt tgacaacctt
    11101 ttcaatcaag gcatcatcag aaactgctgc aagttcaggt atttcattgt ggtgcacccc
    11161 aatttcaagg gagcggcagg ccttgagaag agattcctcg atgttacgac cgattgccat
    11221 gacttctcca gtcgccttca tttgtgtacc gagacggcgt tcaccctttt caaacttgtc
    11281 aaatgggaaa cgtggaatct tagcaactac gtagtcaagg gctggttcaa acatggcata
    11341 ggttgaacct gtaactgggt ttataacctc atccaaggtc aaacctactg caatcttggc
    11401 agccaactta gcaatcggat atcctgtcgc tttagaagca agggctgacg aacgtgatac
    11461 acgagggttt acttcgataa cataatactt gaagctgtta ggatcaagag ctagctgaac
    11521 attacatcca ccttcaatct tgagggcacg aataatgctc aagctcgcat cacgaagcat
    11581 ttggttttca tagtctgaca tggtttgcgc aggggcaaat acaatggaat cccctgtgtg
    11641 aatcccaact gggtcaaagt tttccatgtt acaaacaacc aaggcattgt cagctgagtc
    11701 acgcatcact tcgtattcaa tttccttgaa accggcaatc gaacgctcaa tcaaacattg
    11761 ggtaacaggt gacaatttca aaccattttc agtgatttca cgcaattctt tctcgttggc
    11821 acacatacca ccaccagtac caccaagggt aaaggctgga cgaacgatga ctgggtagcc
    11881 aattgtcgct gcaaaggtaa ctgcttcttc tactgtgtta acaatttcag attctggaat
    11941 gggttgttca agctcttcca tcaattgttt aaagaggtca cggtcctccg cttggtcaat
    12001 ggcagataat ttggtaccca gaagttcaac gccaagctcg tctaggatac catttttaga
    12061 taattccatg gccatgttga gacctgtctg accaccgagt gttggtagca aggcatctgg
    12121 acgttcctta cgaagaatac gtgtcacaaa ctcaagtgta atcggttcaa tgtaaacctt
    12181 gtcagcaatt tccttgtccg tcatgatggt tgcaggattt gagttaacca aaacaacctc
    12241 ataaccttcc tctttcaacg acaagcaagc ctgggtccca gcatagtcaa actcagcagc
    12301 ctgaccaata ataatcggac cagaaccaat caccataatt ttttgaatat cagtacgttt
    12361 aggcatatat aagatattaa gggtgtcaag cggacaaagc taaaatagga gttatgacga
    12421 agaactgtca gttctaggaa taactatctt tttagcaccg tccgtagccc gtattcagtt
    12481 cagcaaatac ggagcaccct tctcctttct attcgtcgcc tctcagggcg acattaaata
    12541 agatacaaag gacgaataga aagcgattga attttaggaa atcaaggaag gattgacaat
    12601 ccaagttggt ttctctacat tctgagcttt ccgtccgtgt tcagttacat aaattctccg
    12661 acgagctttt actcgttctt agtttgattg tttaaaaact tccatcatct cgataaactc
    12721 gtcaaatagg tagctagcgt cgtgtggccc aggagctgca tctgggtggt attgaacaga
    12781 gaaagcaggt tggtatctgt ggcgcacacc ttccactgac ttgtcattga tttcttcgtg
    12841 ggtaataatc aagtgctctg gcaaatcctc gcggctgact gcataaccat ggttctggct
    12901 ggtgaagtct actcgtcctg ttgcgatttc acgtaccgca tggttgaatc cacggtggcc
    12961 aaacttcatc ttataggtct tagccccgtt tgccattgca aagagttggt gtcccataca
    13021 aataccaaag attggaattt ttccttgtac accgcgaatc atgtcgagtg cttgtggaac
    13081 gtcttctggg ttacctggac catttgacaa cataactccg tcaggattga gatggagaat
    13141 ttcttcagcc gttgtcgaat aaggaacaac tgtcacgtta cagttgcgtt tagaaagttc
    13201 acgtaggatt gagtgcttga gaccaaagtc cactagcacc acgctcaaac caactcctgg
    13261 agctggataa gacgttttag tagaaacctg tttgatattg tctgtcggta aaactgttgc
    13321 ttggagctgg tccgtcacat ggtccatact gtccccaaca tgggtcaagg ttgcacgcat
    13381 agtaccatgc ttacggataa tcttggtaag agcacgcgta tcaattcctg aaatccctgg
    13441 aattttcttg gctttcaaaa attcatccaa ggtcatttgg ttgcgccagt tgctagctct
    13501 acgcgcttct tcaaaaacaa cgactccctt acaagttgga ataatggatt cataatcatc
    13561 acgattaata ccataatttc ctaccaaagg ataagtaaag gtcaagattt gtccattata
    13621 agactggtct gtaatggatt cttggtagcc ggtcatccct gtattaaaga cgatttcgcc
    13681 tgttacatca atatctgctc cgaaggcctt gccttcaaaa actgtgccat cttctaatac
    13741 tagaattctt tttgtcatat tttcacctct cgtggacgct cactggcgtc ttttaacgtc
    13801 ttgtgtttta gttggcgttt ctactcgcta gtacagattc taagattgcc attcgaacaa
    13861 agacaccatt ggtcatttgt tggacaatcc gtgattttgg tgcttcaacc aagtggtctg
    13921 ctatttctac atcacgattg attggagctg ggtgcatgag gattgctgtt tctttcaaac
    13981 gatcgtaacg ttcttgagtc aagccatgtt gggcatggta gtcttctttt gaaaatacag
    14041 ctccactatc atggcgttcg tgttgcacac ggagaaacat catgacatca acctgatcaa
    14101 tgatttcatc aatggttaca aactgtccat agtctgcaaa ctcttgactt ctccattcct
    14161 caggtccagc gaaaaagagt tcagatccca agcgtttcaa aatctgcata ttggatttgg
    14221 caacgcgtga gtggtccaag tcacctgcaa tagcaacttt aagaccctca aagtggccaa
    14281 attcctcata aatggtcatc aaatcaagca agctctggct agggtgttgg cccgaaccat
    14341 ctccaccatt gatgatggaa gtcgtaatcg ttggactagc aatcaattct ctatagtagt
    14401 cgacctctgg atggcgaatc acacagacat ccactcctaa agcagacaga gtcaaaatgg
    14461 tgtcataaag tgtctcaccc ttattaaccg aactagtctt cacatcaaag tcaagtcgtt
    14521 ccaatccaag tttaatctct gcgacttcaa aggacttatg tgtccgtgta gaatcctcaa
    14581 agaagagatt ggaaacaatc ggatggtctt catagggaag ctgggctcca tttttaaact
    14641 caattcctcg cttgatcaat ttcattactt gatcgacagt gaggtcttcc atggacacca
    14701 catggttcaa tgcttgttga ttttctgaca tggctactcc tttaactttc taagcttctt
    14761 cagtaatcag aactctgtct tggtcatcaa gttctgtcat ctctacgatg atttcttcag
    14821 aacgactggt tgggatattt tttccaacgt aatctggacg gattggcaat tctctatgtc
    14881 cacgatcgac tagaactgct aaactcacac gcgcaggacg accatgaccg acaatattat
    14941 caatagcagc acggatggta cgacctgtat agagcacatc atccaccaag ataacttcgc
    15001 ggtctgtcac atcgacagaa accaaagaag tatcttctcc acttttaaca tcatcacgga
    15061 aaggtttagt atccaattcc acaacaggaa ctgaaagatt ttctaactgc ttcaaacgtt
    15121 cttggattcg gtgggcaata aagacaccac gagttttaat accagccaag acaatcttat
    15181 tcaaatcttt gttgcgttcg ataatctcat aagtaatacg cgtaatcgct cgtttgacgg
    15241 tcaattcgtc tacaacttct tttgttttca tgacaaacct ccaaaaagaa aagtctcctt
    15301 aaacaaggag acttgaaatt tatagccaag cgagccctac tgcacacagt atagacttca
    15361 cccttctact ttatcgcgct ccttgcctgc ctcacgggac aggtttaaag gaatatttag
    15421 ttatcattta ctatagcaca aagcatgctt aaaatcaagc aaaaagtttc aatgtagcat
    15481 cttacaaatt gctaaaatca tataattgtg ggtactggtc acactctgga ttttttggat
    15541 ggcaaatggc tcttccaaaa taaatcatgg cctgatgggc agctaaccac tgctcaggcg
    15601 gcaagatatc catgacccgc ttttccacct caagtggcgt cgctgatttt ttgacaatat
    15661 cgtggtgttt gcaaatacgc tccacatgag tatccactgc aaaggctgga atcccaaatc
    15721 ctacactcat gacaacattg gctgtcttgc gaccaacacc tgccaaactc tccaattctt
    15781 cacgtgtctg agggacttga ccatcaaaat cgtctagtaa ctgttgggca cattttttaa
    15841 ggaatttagc tttattccga tacaatccca agcgagaaat atgtgaagca atctcactct
    15901 ctgtcgctac agacatagct tggggtgttg gaaaggcaac aaagagacct ggtgtggcct
    15961 tatttaccgc tgcatctgtc gtctgggctg ataacatgac cgcaaccagg agttcaaaat
    16021 gattggtaaa atcaagacta ggcttggcat ctgggaagag ggcaatgatt tcttctagca
    16081 cctttcgtgc tcgttttttt gacaagacca ttattcatct ccgtcaaata gtccttgtaa
    16141 gccagcaaaa ggactgtttt cttctttctt tactgcttgt tgagcttggt attcttcctc
    16201 tgtcatgatt tgccagtcat ttcctgagac aaatccttga ccagcttctt cttcagccgt
    16261 caagaccttg ataggaatgt ttagcaggat attgtctgat acactctcag caaggtcaag
    16321 cgccccattt tcgatgggca agaccaagtc atcatctaaa atttcttgat ttagatggtt
    16381 agttgcgcct tccatgaaaa cttccgtgac tggataagat tcaactaact caactggctc
    16441 catactgcga ctcgaagcaa gaacaatggt ataagatagt tgataatcta agaaatacat
    16501 acggtcttca tattgtactt tcccaactgc aaggatatct tttacatcta aaatttcttg
    16561 attacgtgca cgcaggtcat caactaaatc taacgtttgt tcaaagttca aaccttcaga
    16621 ctgcttacga atttcttgaa tatttaattt catacttcct ccataaagat ttactctctt
    16681 gattatacca tgaaaaggct acaaatcagc acaccaaact ttgtaattaa aattcaaaat
    16741 tttaacatat ttactatgat agttttgttt tttagtgcta tactataggg aaagagtaca
    16801 tcagatcaag gaggatgctc acatggaaga caagaaactc attcaactcc tatccaagtt
    16861 aaataaaagc taccaaaact gtaaacaggg tacggcagat gatattcgac tacaagagct
    16921 gctaaacact actatgcaag agctcaaaaa aacggaacag ttgaacaaca gtatcttaat
    16981 tgatcttgag aaattttacc aacccaccag tcctctgatt ggactgggta gcctaaaact
    17041 aaacaatcaa gcacgcactg cttggcgaaa ctatgataaa atccattacg agcatgtcaa
    17101 acacgtacta agtctctatg gacctgtttt tggattttag agcatagaat ttccagtttt
    17161 ctgttgacaa aatttcctta aaggtatagt ataaagatac taatactcgg aggtaaggga
    17221 gacatgaaca actaagtcta tcaaataaag aacctttatt tagtagatct tgtttttgtc
    17281 tctttttgtg tgctctttta tgctcttttt ctggcatgtt aatagagttt ttttgacata
    17341 gactttgggc tctactaggt aaagtagagc tttttgttat gcactatgaa cattctagaa
    17401 agggaaatca tatgataaaa atcaatcatc taaccatcac acaaaacaaa gatttacgag
    17461 atcttgtatc tgacctaacc atgaccatcc aagacgggga aaaggttgct attattggtg
    17521 aagaaggaaa tggcaaatca accttactta aaattttaat gggggaagct ttgtctgatt
    17581 tcactatcaa gggaaacatc caatctgact atcagtcact ggcctacatt cctcaaaaac
    17641 ttcccgagga gctgaaaaag aaaactttac acgactactt ctttttagat tctattgatt
    17701 tagactacag tatcctctat cgtttggcgg aggaattgca ttttgatagc aatcgtttcg
    17761 caagtgacca agagattggc aatctatcag ggggagaagc tttgaaaatt cagcttatcc
    17821 atgagttagc caaacccttt gagattctat ttttagatga accttcaaat gacctagacc
    17881 ttgagacagt tgattggcta aaaggccaga ttcaaaagac caggcaaacc gttattttca
    17941 tttcccatga tgaagacttt ctttctgaaa cggcagacac tattgttcac ttgcgactgg
    18001 tcaaacaccg taaagaagcg gaaacgctag tagagcattt agactatgat agctatagtg
    18061 agcagagaaa ggctaatttt gccaaacaaa gtcagcaagc tgctaacaac caaagagcct
    18121 acgataaaac catggaaaaa catcggagag ttaagcaaaa tgtagaaact gcgcttcgag
    18181 ctaccaaaga tagtactgcc ggtcgcctat tgtctaaaaa gatgaaaact gtcctctcac
    18241 aagaaaaacg ctacgaaaag gcagctcagt ccatgactca aaaaccactt gaagaggaac
    18301 aaatccaact tttcttttca gacatccaac cattaccagc ttctaaagtc ttagtccaac
    18361 tggaaaaaga aaatttgtcc attgacgacc gagttttggt tcaaaaacta caactaactg
    18421 tccgtgggca agaaaaaatc ggtattatcg ggccaaatgg tgttgggaaa tcaactctgt
    18481 tagccaaatt aaagcaactt ctgaatgata aaagagagat ttcccttggt tttatgccac
    18541 aagattacca caaaaaacta caattggatt tatcaccaat agcttatatc agcaaaactg
    18601 gggaaaaaga ggaacttcag aaaatccact ctcacctagc cagtctcaat ttcagttatc
    18661 cagaaatgca gcatcaaatt cgctccttat ctggcggaca acagggaaaa ctcctgcttt
    18721 tggatctagt cctgcgcaaa ccaaactttc tcctgctgga tgaacccaca cgaaactttt
    18781 ctcccacttc tcaaccccaa atcagaaaac tctttgcaac ctatccaggc ggtctcatca
    18841 ctgtttcgca tgaccgtcgt ttcttaaaag aagtctgctc gatcatctat cgcatgacag
    18901 aacacggttt ggagttagtt aatttagaag atttataaat ttgcaacata gcaaaaatcc
    18961 agagacgacc tctggattct tttacatctg ttttaaacgt tcaatccgtt ctgagatagg
    19021 tgggtgggta taaaagagtt tttggaaccc cccacctttc ttgggatcat tgatataaag
    19081 agcactgcta gcatcatcga cgtggcgact catcggtttg ctattgtcca acttatctag
    19141 ggcattaatc attccctggg gattgcgagt cagctcaaca ctagatgcat ctgccagaaa
    19201 ttccctctga cgagaaatag cgagctgaac caaggttgca gcgagaggtg ccagtacaat
    19261 agctagtagg gaaaccacta gcataatgat ttcaagacca tttccatctc ggtcatcatc
    19321 acttcgtctg cgacctgctc caccccacca catcatacga cctgccatac cagaaagcat
    19381 ggtgatagca ctagcaaggg caactgcaat agtcgaaata cggatatcat aattacgaat
    19441 atgactgact tcatgtccca taacagcttc tagttcttca cgattcatga tagctagtag
    19501 acctgaagtc gcagcaacag ccgcattttg aggattagaa cctgtcgcaa aggcatttaa
    19561 ggctggatca tcaatgatga aaacacgggg cataggaatc tgggcgacca gagccatatc
    19621 ttccactaca tggtagaggt ctggtgccgt ttgctcatcc acctcacgcg ctccattcat
    19681 ggacatgaca atctctgtcg attgaaaaat catagacaaa gcgtagataa agccgataat
    19741 cagtgcgata accaaaccac caagtccaga tcttataaag agataaccaa ccgcataacc
    19801 aacaagagct aagagtagga aaaataccag caacaaaatc caggtttttc gtttattgct
    19861 tgcaatttga tcaaacaaca tcttagtcac ctaaaccgct aaaatcaact ttaggaaccg
    19921 acttttcctc ttcaggtgtt tgaaggaaat ctgccgcttt aaatccaaac attccagcga
    19981 taatattgct cgggaaagtt tctaatttta cattgtagtt gctgacaaca ctgttataga
    20041 gttgacgaga gtaagaaatt ttattttctg tgtttgtcaa ctcctcttgc aatttaacaa
    20101 agttagcact agctttcaaa tctggatagc tttctgcaac tgcaaaaata cctgaaacct
    20161 gacgagtgag ggcatcactg gctttcatag cttctgctgg tgaagtcgct gccgccactt
    20221 ggttacgtag ttctgccacc ttttcaaggg tagaaccttc atatttggca taacctttta
    20281 cagtctcaat caagtttggc aagagatcat tgcgacgttt caactgaaca tcaatctgac
    20341 tccaagcctc cttggtttgc atacgatttt taaccaaacc gttatagcta acaattacaa
    20401 aaataacaac aagagctaaa actccaagaa taatccaagt cataatataa gtcctttctg
    20461 cttttagatt agtactagta tatcaaattt tctatgattg tggtaaaata agatgatact
    20521 aaagaaggaa ataactatga aaccaaaaac attttacaac ttgcttgccg agcagaatct
    20581 tccactttcg gaccagcaaa aagaacaatt tgaacgttat tttgagctct tggtcgagtg
    20641 gaatgagaag attaatttga cggcgattac ggacaaggaa gaagtttatc tcaaacattt
    20701 ttacgattcg attgcaccca ttcttcaagg tttgattccc aatgaaacta tcaaacttct
    20761 tgatatcggg gctggggcag gatttcctag tctaccaatg aaaattctct atccggagtt
    20821 agatgtgacc attattgatt cactcaataa gcgcatcaac ttcctacaac tcttggctca
    20881 agaactggat ttgaacggag ttcatttcta ccacggacgt gccgaagatt ttgcccaaga
    20941 caagaacttc cgtgctcaat atgattttgt aacagctcgt gcggttgccc gtatgcaggt
    21001 cctatctgaa ttgactattc cctaccttaa ggttggtggc aaactattgg cactcaaggc
    21061 cagcaatgcg cctgaggaat tattagaagc taagaatgcc ctcaatctcc tttttagtaa
    21121 ggtcgaagac aatctcagct acgccctacc gaatagagat ccgcgctata tcacagtggt
    21181 agaaaagaaa aaagaaacac caaataaata tccacgtaag gctggtatgc caaataaacg
    21241 cccactttaa attttttagt aaacaaatgt ttacaaaatc agcctcgctc ttttatttct
    21301 aggctcggga aaaaatgatt tacaaaatca gcctcgctct tttatttcta ggctcgggaa
    21361 aaaatgattt acaaaatcat ttttttctgc tatactatcc taagcaaagg tttttaatgt
    21421 catcccgtga ggtgacgaag acacaaaaat atttgaaact ctttaaagtc tagattttag
    21481 agaagtctta ctctgagggc ctattgctgt aaaataatgg gctcttttct gatgcccaaa
    21541 agtgaggttt atatgaaaca agaatcaact gttgatttgt tactagacgt tgaccaacgt
    21601 ccttcggatg gaaaaggaat tctccttagc ttccaacacg ttttcgccat gtttggtgcg
    21661 accatcttgg taccattgat tttgggaatg cctgtatctg ttgccctttt tgcttcaggt
    21721 gttggaacac tcatctacat gattgctact ggttttaaag ttccagttta tctaggttct
    21781 tcatttgcct ttatcacagc tatgtcactg gctatgaaag aaatgggggg tgatgtatct
    21841 gctgcccaaa caggggttat cttgactggt ttggtctatg tccttgttgc taccagcatc
    21901 cgatttgtag gaacaaaatg gattgataaa ctcttgccac caatcattat cggtcctatg
    21961 atcatcgtta tcggtcttgg acttgcaggt tcagctgtta ccaatgcagg tcttgtagca
    22021 gacggaaatt ggaaaaatgc tctggtagcc gttgttactt tcctaattgc tgcctttatc
    22081 aatacaaaag gaaaaggctt cctacgaatc attccattcc tctttgccat tatcggtggt
    22141 taccttttcg cactaactct tggcttggtt gactttacac cagttcttaa agccaactgg
    22201 ttcgaaattc ctggtttcta cttgccattt agcacaggtg gtgcctttaa agagtacaat
    22261 ctttactttg gtccagaagc catcgctatc ttgccaatcg ctatcgtaac aatttctgaa
    22321 catatcggag accatactgt tttgggtcaa atctgtggcc gtcaattctt aaaagaacca
    22381 ggtcttcatc gtactcttct tggtgacggt atcgcaactt ctgtttctgc cttccttggt
    22441 ggaccagcca atacaactta cggagaaaat acaggggtta tcggtatgac tcgtatcgct
    22501 tctgtctcag ttatccgtaa cgctgccttc atcgcgattg ccctcagctt ccttggtaaa
    22561 ttcactgcct tgatttcaac tattccaaac gctgtacttg gtggtatgtc aatccttctc
    22621 tatggggtta tcgccagcaa tggtttgaaa gtcttgatta aagaacgtgt tgatttcgct
    22681 caaatgcgaa acctcatcat cgcaagtgct atgttggttc ttggacttgg aggagctatc
    22741 cttaaacttg gtccagttac actttcaggt actgcccttt cagccatgac aggaatcatc
    22801 ttgaacttga tcttgccata cgaaaataaa gactaagagc ctaaatacac ctaatccact
    22861 caaacagctg agtggatttt tcgcatacca taataaaagt gtcttaacaa aattattaaa
    22921 atcaaaaaac gtataatatc agatattcta aaaccttgat actgtacgtt ttatcataga
    22981 aatttttact ttattttctc atcaaatgag atttgcatca atctcttgtc ttacttgcgt
    23041 ttcttcttcg ctttcttcat tttgttagcc atacgtttca tggactgttt catggcaaat
    23101 tcaccaattt tacctttcaa accgccacca aacatctggc tcatatctgg cattcctgct
    23161 cctccgagag ctgataagtc aggcataccg ccttgtccca tcattccttc aagggcagac
    23221 atatccattc ctcccatatt tggcatattt ttaggaaggt tatttggatt aatccccatt
    23281 tgcttcatca ttttattcat atccccagac ataacaccct gcatgagctg tttagcctgg
    23341 ttaaagtcct tgatgaattt attgacttcg acgaatgtat ttccagaacc agcagcaata
    23401 cgacggcgac ggcttggatt taacaaatct gggttttcac gctcttcagg tgtcatcgaa
    23461 gacacaatgg cacgtttacg agcaatctgg cgttcatcca ccttcatgtt ttgaagggct
    23521 ggattgttgg ccatacctgg aatcatcttg agcaagtctt ccatcggccc catattttgc
    23581 acctgatcta attgatcgat gaaatcatta aaatcaaagg tgttttcgcg catcttctca
    23641 gccatttcaa gggctttttg ttcatcgtat tcctgagaag ctttctcaat caaagtgagc
    23701 atatccccca taccaaggat acggctagac atgcggtctg ggtggaaggt ttcaatgtcc
    23761 gtaatctttt cacctgtacc agtgaacttg attggttttc cagtaatgtg acgaacagac
    23821 agagcagcac caccacgagt atcgccatca atcttggtaa ggatgacccc agtcacttcc
    23881 aactgagcat taaactcacg cgcaacattg gctgcttcct gaccaatcat agcatcaacg
    23941 acaagcaaga tttcatttgg ttgagccaat gctttcacat cacgaagctc attcatgagg
    24001 agctcatcaa tctgcaaacg acccgcagta tcaatcaaga catagtcgtt atgattagtt
    24061 tgggcttgct ccaaaccttg acgtacaatc tcaacagctg gtacttctgt tccaagtgca
    24121 aagacaggca catcaatctg ttgtcccaag gtcttaagct ggtcaatggc agctggacga
    24181 taaatatccg ccgcaatcat caaaggacga gcattttctt ctttcttgag tttgttggcc
    24241 aatttaccag caaaggttgt tttaccagcc ccttgtaaac caaccatcat gatgatggtt
    24301 ggaatcttag gtgacttgat aatttctgcc gtatcagaac ctaaaacggc tgtcagttcc
    24361 tcatcaacga ttttaataat ctgttgcgca ggattaagtg tatcaatgac ctcatgcccg
    24421 actgcacgct cacgaacttt cttgataaag tcctttacaa caggcaaggc aacgtcggcc
    24481 tcgagcaagg ccaagcgaat ttctttggtt gcctcttgga catcagattc agagattttt
    24541 ccttttttac gtagattttt aaagacgttc tgcaaacgtt ctgttaaact ttcaaatgcc
    24601 atttttcttc ctcttattct ctattatcaa tgcttgttaa aatttctatc tgctcctgca
    24661 gaaagttatc cttgggatag cgctccaaaa tctgatcaaa aatctgactg cggacaatat
    24721 agtccgagta catgtgcaat ttcatctcat aatcttccag aatcttttct gttcgcttga
    24781 tattgtcata gacagcctga cgactgacac cgaactcctc ggcaatttca gcaaggctgt
    24841 aatcatcagc gtagtagagc tcgatataat tcatttgctt atctgtcaaa agcgccgcat
    24901 aaaattcaaa gagcgcattc atacgattgg ttttttcgat ttccataact tttattatac
    24961 caaaaattag cctaatctac cacactagga agccgatcca agaagataga tagctaaatt
    25021 tgaaaaagac atgagcctag ccccaagtaa tttccaattg atagctggca aagggatgtc
    25081 cctcttgatt ttgtagttga taatctagtt caatcttttg cccatccact tgataacgat
    25141 tcgtttggat aataaactcc tgcataccca taggtgtggg aatataggct aaactatcac
    25201 tatcctttag aaagcgcata atggtcttgg gattggaaaa tcgactcatc acaagttctt
    25261 gaccatgaaa tttaatcact actttttcct tttcctcatt atagaaaagc aggtagctat
    25321 aatctccttt ttcatgcact tccacatcat aaagctggtc aatcacttcc aactgctcat
    25381 caaactgaat tgtatttcgc atccgaatct tcacatcagg ccctctttct tgtctcttgt
    25441 cctactattt taccaaaaag agcaggattt tgctataatg gtcatatgaa cgaaaaagta
    25501 ttccgtgacc ctgttcacaa ctacatccat gtcaataatc aaatcatcta tgacttgatt
    25561 aatacaaaag aatttcagcg tttgcgccgg atcaaacaac tgggaacttc cagttatacc
    25621 ttccacggtg gagaacacag tcgcttctct cactgtctag gagtctatga aattgcacga
    25681 cgcatcacag agattttcga agaaaaatat cctgaggaat ggaatcctgc cgagtctctc
    25741 ttgaccatga ccgctgctct cctacacgac cttgggcatg gtgcctactc ccatactttt
    25801 gaaaatctct ttgatacaga ccatgaagcc attactcagg agattattca aaatcctgag
    25861 acagagattc accaagtcct gctacaagtg gcacctgatt tcccagaaaa ggtggccagt
    25921 gtcattgacc atacctatcc taataagcag gtcgtgcagc tcatttctag tcagattgac
    25981 gcagatcgca tggactatct cttgcgcgac tcctatttta caggagcatc ctatggggaa
    26041 tttgacctga ctcgaatcct ccgagtcatt cgtcctatcg aaaatggtat cgcctttcag
    26101 cgcaatggca tgcacgccat cgaagactac gtcctcagtc gctaccagat gtacatgcag
    26161 gtttatttcc accccgcaac acgcgccatg gaagttctcc tacagaatct tctcaaacgc
    26221 gccaaggaac tctatcctga ggacaaggat ttctttgccc gaacttctcc acacctcctg
    26281 cctttcttcg aaaaaaatgt gaccttgact gactatctgg ctctggatga tggcgtgatg
    26341 aatacctact tccagctttg gatgaccagt cctgacaaga ttcttgcaga tttatcgcat
    26401 cgctttgtca accgcaaggt ctttaaatcc attacctttt cacaagaaga ccaagaccaa
    26461 ctcgctagca tgagaaaatt ggttgaggac attggctttg atcccgacta ctatactgcc
    26521 attcataaga actttgacct cccttatgat atctatcgtc ccgaatctga aaatccacgg
    26581 acacagattg agattttaca aaagaatgga gaactggccg aactctctag cctgtctcct
    26641 atcgtccaat cccttgctgg tagtcgtcac ggagataatc gtttctattt tccgaaagaa
    26701 atgttagatc aaaacagtat ctttgctagc attacccagc aatttttata cttgattgag
    26761 aacgatcatt ttaccccaaa taaaaactag aagaggaaat ttatgagtat taaactaatt
    26821 gccgttgata tcgacggaac ccttgtcaac agccaaaagg aaatcactcc tgaagtcttt
    26881 tctgccatcc aagatgccaa agaagctggt gtcaaagtcg tgattgcaac tggccgcccc
    26941 atcgcaggtg ttgccaaact tctagacgac ttccagttga gagaccaagg tgactatgtg
    27001 gtgaccttca atggtgccct tgtccaagaa actgctactg gccatgagat tatcagcgaa
    27061 tccttgacct atgaggatta tctggatatg gaattcctca gtcgcaagct cggtgtccac
    27121 atgcatgcca ttaccaagga cggtatctat actgcaaatc gcaatatcgg aaaatacact
    27181 gtacacgaat caaccctcgt cagcatgcct atcttctacc gtacccctga agaaatggct
    27241 ggcaaagaaa ttgttaaatg tatgtttatc gatgaaccag aaattctcga tgctgcgatt
    27301 gaaaaaatac cagccgaatt ttacgagcac tactctatca acaaatctgc tcctttctac
    27361 ctcgaactcc ttaaaaagaa tgtagacaag ggttcagcta ttactcactt agctgaaaaa
    27421 ctaggattaa ccaaagatga aaccatggct atcggagacg aagaaaatga ccgtgccatg
    27481 ctggaagtcg ttggcaaccc tgttgtcatg gaaaatggaa atccagaaat caaaaaaatc
    27541 gccaaataca tcactaaatc taatgatgaa tctggcgttg cccatgccat ccgtacatgg
    27601 gtactgtaaa aggaaagaat agactaaaac cgctcagttg agcggttttt gatgtctaat
    27661 tactgccccc tgcaggaatc gaacctgcaa ctactcctta ggagggagtt gttatatcca
    27721 ttgaactaag ggagctagat aaaaactctg ctgaaaagca gagtttttta gtcgaattaa
    27781 cgacggattt ctttgatacg agctgcttta ccttgaagag cacgcaagta gtacaatttc
    27841 gcacgacgta ctttaccgta acgaacaact tcgatttttt caacacgtgg agtgtggatt
    27901 gggaagatac gctcaacacc tacaccgtta gagattttac gaactgtgta gttttctgag
    27961 attccagcac ctttacgtgc gataacaaca ccttcaaaaa tctggatacg ttcacggtta
    28021 ccttcgacaa ctttcgcatg tacacgaaca gtgtcaccag gacggaatga tgggatatct
    28081 gtacgaagtt gaccttcagt caagctttgg attaatggat tcattttatt ctcctatctt
    28141 tgtcaatctt gaggaaactt cctcagcgga taaactgtat ttttgtgcgt ccatcacaca
    28201 caagatacag tctaccaaat tttcacaaaa aagtaaagaa atttatagca aaattcctaa
    28261 aaaaatcgca accaaaccac ctatgtaagt caaagtcagg taagaataaa agaccttctt
    28321 atcacttagc agtctttgaa gttcgtcatt caaggtcgaa aaagttgtta aaccgccaca
    28381 aaatcctgtt gctagaatag catatacttc cttagactct acatgattgt agaatactcc
    28441 aattaaaaaa caacctaaaa gattagctat gagcgttccg agtggcaatt tagaagcttg
    28501 attgtagcgg gaaaagaaat accgtacgag tgctcccaag ccacaggcga ttgcaagata
    28561 gacgattacc atttcttcct ccccaaatag taagctaaaa gcaggcctcc accgatactc
    28621 aaaagcaaat acagtatcaa actaagataa cgccctgtat ccagtaattt cacagcatca
    28681 agcatgagac tagaaaaggt tgttaaacct ccgcaaaaac ctgtacccag tgctaaaatc
    28741 aagcccttac tagttccctt ataaaccaga tagcccttaa caagataaat caagcagaaa
    28801 atgcctagat agttgacaag aagggttccc cagggaaaat ctggactggc tggtaaccaa
    28861 atggaaacca gatagcggat aagtccgccc aacatggcag ctataaaaat gcctagcgga
    28921 taaaattgtt cttttttcat ttgatatttt gatcctgata atcacgcgaa cgtttgagta
    28981 tatccgaaaa agtcgctaca atagtctcct gatagcgctt gtcctctaca cgactcccaa
    29041 ccttttcaaa aataacttct tctctcttag tatctaaaat cggtttacct gaagctttct
    29101 tataagcaac caccccctca actaaatgca ttcgttcttc taacagtttg acaatttggt
    29161 cgtcgatttg atcgatttct tgacgaataa tatctaaatc catacagtct cctcctttat
    29221 ttgaattatt gtatcaaaaa gccatcaatt aggctagtaa aatcccaact ctcgataaga
    29281 aaaatgcact gattgattac atcagcgcac ttttatgctt atcctacttt agcagccaat
    29341 tcttctacga attgttccaa gcgttcaata tcttcttcct cggcagaaag atcaactttg
    29401 acacactcag aacctttttc tgctcctgtt gaaacaaaga cacggtcaaa gtcatcaaca
    29461 gccttacaga attcatcgta gaaggtatct cctgagccga ccactccgta gattttgcca
    29521 ttcaagttga gatctgctag atcttcgtag aagtccatca tctcatctgg caattcacca
    29581 tcaccataag tataggtcgc aacgatagcg atgtctgctt ccaagaagtc tgaagcgtca
    29641 acagttgtac attcatcaac atcaacatcc aagcccaagt cacgtaattt gtctgctaca
    29701 atatctgcaa tttcttcggt attaccggtc atactggcaa atacaatttt tgctaatgcc
    29761 atatcgtcct cctcaattta tctttctcca ttatatcaca tctttttcat tttaaaaata
    29821 aaaattcttg tgctacaatg aaatgagaaa gaattgaggt tatttatgga gatttgccaa
    29881 caaattttag aaaaaattaa agaatacgac accattatca ttcatcgtca tatgaaacca
    29941 gaccctgatg ccttgggaag tcaggtggga ttgaaagcct tgctggaaca tcatttccca
    30001 gaaaaaacca tcaaagccgt cggttttgat gaaccaactc ttacttggat ggctgagatg
    30061 gatcttgttg aagatagagc ctaccaaggc gcacttgtca tcgtctgtga tacagctaat
    30121 actgctcgta tcgatgataa gcgctatagt caaggtgatt ttctcattaa gattgaccac
    30181 catccaaatg atgatgtata cggtgacctg tcttgggtcg atactagttc aagtagcgct
    30241 agcgagatga ttaccctatt tgcccaaaca acccaactag ccttggcaga tcgcgatgct
    30301 gagttgctct ttgcaggaat tgtcggtgat acaggtcgct tcctctaccc ttctaccact
    30361 gcacggactc ttcgcctggc tgcttatttg agagaacata actttgactt tgcggctctc
    30421 actcgcaaaa tggacactat gagctacaaa attgctaaac tgcaaggcta catctacgac
    30481 catctggaag tggatgaaaa tggtgctgct cgcgttatcc tgagtcaaga agtcttgaaa
    30541 caatacaatg taaccgatgc tgaaactgca gccattgtcg gtgcacctgg acgcattgac
    30601 agagtgagtc tctggggaat ttttgtcgaa caggctgatg gccactaccg agttcgctta
    30661 cgcagtaaaa tccatcctat caatgaaatc gccaaggagc atgatggtgg aggccaccct
    30721 ctagcaagtg gtgctaattc ctatagccta gaagaaaatg aaatcatcta ccaaaagtta
    30781 aaaaacttgc ttaaaaactg ataaaatact tgccaaactt ttcagaatct gatagactag
    30841 tatggtaaca atctatggct cgcaaagaga ccatggcaga aaggaaatat tgcaaaatga
    30901 aaaaagatat ccatccagaa tatcgcccag ttgtcttcat ggacacaact actggttacc
    30961 aattccttag cggttcaaca aaacgctcta acgaaacagt tgagttcgaa ggcgaaactt
    31021 acccattgat ccgtgtggaa atttcatcag actcacaccc attctacact ggacgtcaaa
    31081 agttcactca agcagatgga cgcgtggatc gtttcaacaa aaaatacggt ctcaaataat
    31141 gataaaagaa cagtttcgac tgttcttttt tgtttcttga aatcaactgc tgttttcatg
    31201 ttccagactc atctgtaggt tcggtttcca tgctactagg caggaaggaa atagctgttt
    31261 caacacgtcc ataatgagct gtactattgt cacgaaccat actttcattg atggtccaag
    31321 tggaattcat tttcttaaag gcctctcgaa ccttttccaa atctttggag gcaatggcct
    31381 gctctaaggt ttcaaaacga ggacttagac ggtttaccaa tttttccttt tccgcatcta
    31441 ggtcaacagg attttgttct ttttcaaaag ctaatagagc tgaggaaatt tcggtgagtt
    31501 tggcttcagt aatatctcca gatagagcta acttttcctt aacaatctta ccaacctcag
    31561 aatccttatt ttctactctt tcgaagtctg atgccatctt cgtaacgagt ttctgggtct
    31621 cagtctgacc accattttta acagctttgg atgcatctgt gattttcaca aagaaaaaac
    31681 tcaagctttc ttgggcacct gctggggaaa gaattaaaaa tgacaaagct aaaactagta
    31741 accagctttt agccttccaa taatttctga ccaatgtagc ctcctttctc cacaccacca
    31801 aagcaagtaa aaagtccact acctatgtga gtgatgtatt cattcatctt atcagtagca
    31861 cctaggttag tttgaacctt aacaaagtta tcaggatcct tctggaaaga aatgaagagc
    31921 aatcccgtat caaactgacc agtcttttca tcaatgccat ctgagtaaga gtaagaacaa
    31981 cgcaaaagtg gcttgtccac ttacttagcc aaacgaacat gcgaatcatc tagcaaaaaa
    32041 ctcaaattca cttcatcaaa ctcatttttt taccgaaagg ggcactactt tccttgtaac
    32101 gaccaaaggt attttcttgt tcttcgagac cagtgcggtc ccaggtctct aaaaacatct
    32161 gaatccgacg aactgccata taagaaccat tttccatcca gtccttacta tcagcccaga
    32221 taacgcggtc aaagtcttgc tccttggttg gatttgctgt tccatcctta aaaccaaaga
    32281 ggttccacgg agtctccatt cgtccccgat agctgcaaat ccagactgac tccaacgaag
    32341 gggcaccgca tttctcccct tacgtatgag attgcgaata acgtgaaagg caatttgctc
    32401 atcatctgca caagcatgaa tcacaatatc tccaccagta tatttttcac gtaattgctc
    32461 cttaggaaat agaggtaaat ccctgaacag tcgagggcgc ttgttttcca agttcatctt
    32521 tttcaagaaa cttgcagata caccaaaagt cagcgtcaaa cgatgaggat tgagcccaac
    32581 tgtctcacca gtatcgctcg gaggaaagag agcattctgt ccatcttttt taaccaattc
    32641 cccctcgacc aacttggcac tataatccgt ccaatcctta aatagctgga taattttatc
    32701 tctatccgtc gtatgcaggt ccaagacaac aaaatagata ttcttttgca tgggcgtact
    32761 atttggtaca tcaagcgaac cttacgaaaa cgtctactga ttttaaagcg ctttcttgtc
    32821 ttcttgaatt gagattttat ttttagacgc gacaatggtt tgagcgtctg ctttcttagg
    32881 atgttctgga cgtggcataa tatttcgcca
//
LOCUS       DBEJAU010000021        32137 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC323 isolate 683620
            SAMN38261939-rid24807223.denovo.021, whole genome shotgun sequence.
ACCESSION   DBEJAU010000021 DBEJAU010000000
VERSION     DBEJAU010000021.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261939
            Sequence Read Archive: SRR26833919
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 32137)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 32137)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576303.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576303.1
            Genome Coverage       :: 154x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/19/2025 01:05:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,121
            CDSs (total)                      :: 2,078
            Genes (coding)                    :: 1,943
            CDSs (with protein)               :: 1,943
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 36
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 72 of 135
            Pseudo Genes (incomplete)         :: 63 of 135
            Pseudo Genes (internal stop)      :: 51 of 135
            Pseudo Genes (multiple problems)  :: 46 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..32137
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261939-rid24807223.denovo.021"
                     /strain="GPSC323"
                     /isolate="683620"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            4..77
                     /locus_tag="ACL29Z_001008"
     tRNA            4..77
                     /locus_tag="ACL29Z_001008"
                     /product="tRNA-Asn"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:38..40,aa:Asn,seq:gtt)
     gene            complement(196..969)
                     /locus_tag="ACL29Z_001009"
                     /pseudo
     CDS             complement(196..969)
                     /locus_tag="ACL29Z_001009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000436304.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing N-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            1234..1470
                     /gene="comW"
                     /locus_tag="ACL29Z_001010"
     CDS             1234..1470
                     /gene="comW"
                     /locus_tag="ACL29Z_001010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001846364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma(X)-activator ComW"
                     /protein_id="HGR0069335.1"
                     /translation="MLQKIYEQMANFYDSIEEEYGPTFGDNFDWEHVHFKFLIYYLVR
                     YGIGCRRDFIVYHYRVAYRLYLEKLVMNRGFISC"
     gene            1701..2987
                     /locus_tag="ACL29Z_001011"
     CDS             1701..2987
                     /locus_tag="ACL29Z_001011"
                     /EC_number="6.3.4.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000205044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004019 - adenylosuccinate synthase
                     activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_process: GO:0006164 - purine nucleotide biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="adenylosuccinate synthase"
                     /protein_id="HGR0069336.1"
                     /translation="MTSVVVVGTQWGDEGKGKITDFLSANAEVIARYQGGDNAGHTIV
                     IDGKKFKLHLIPSGIFFPEKISVIGNGMVVNPKSLVKELSYLHEEGVTTDNLRISDRA
                     HVILPYHIELDRLQEEAKGDNKIGTTIKGIGPAYMDKAARVGIRIADLLDKDIFRERL
                     ERNLAEKNRLFEKLYDSKAIVFDDIFEEYYEYGQQIKKYVIDTSVILNDALDNGKRVL
                     FEGAQGVMLDIDQGTYPFVTSSNPVAGGVTIGSGVGPSKIDKVVGVCKAYTSRVGDGP
                     FPTELFDEVGERIREVGHEYGTTTGRPRRVGWFDSVVMRHSRRVSGITNLSLNSIDVL
                     SGLDTVKICVAYDLDGQRIDYYPASLEQLKRCKPIYEELPGWSEDITGVRNLEDLPEN
                     ARNYVRRVSELVGVRISTFSVGPGREQTNILESVWS"
     gene            complement(3229..4377)
                     /locus_tag="ACL29Z_001012"
     CDS             complement(3229..4377)
                     /locus_tag="ACL29Z_001012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000876726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HGR0069337.1"
                     /translation="MKYNKTKYPNIYYYETAKGKRYYVRRSFFFRGKKREKSKSGFTT
                     LPQARAALVELEQQIQEQELGINTNLTLDQYWDIYSEKRLSTGRWNDTSYYLNDNLYK
                     NHIKAKFGSILLKNLDRNEYELFIAEKLQNHTRYTVQTLNSSFMALLNDAVKNGNLLS
                     NRLKGVFIGQSDIPAANKKVTLKEFKTWIAKAEEIMPKQFYALTYLTIFGLRRGEVFG
                     LRPMDITQNDSGRAILHLRDSRSNQTLKGKGGLKTKDSERYVCLDDIGTDLIYYLIAE
                     ASKIKRKLGIIKEQHKDYITINEKGGLINPNQLNRNFNLVNEATGLHVTPHMMRHFFT
                     TQSIIAGVPLEQLSQALGHTKVYMTDRYNQVEDELAEATTDLFLSHIR"
     gene            complement(4551..5363)
                     /locus_tag="ACL29Z_001013"
     CDS             complement(4551..5363)
                     /locus_tag="ACL29Z_001013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001174228.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_function: GO:0016818 - hydrolase activity, acting on
                     acid anhydrides, in phosphorus-containing anhydrides
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HIRAN domain-containing protein"
                     /protein_id="HGR0069338.1"
                     /translation="MQKTVEKILFRVAGVTKYKKAVKEACNMIAEDNGIPEYAKYYSN
                     LSTKELREELEEYGLKVFKYQDLDFFNIELVPEIDNRYDPNAIKVLIFDNHVGYVPAT
                     IAKTIRKYFDNKKYNFVIEGEIKGGPYKEWDEYEEKVVTNNDLDVGFEIYLTIVDSSQ
                     KEVIQSESSEIIDDNISNKEVTETEAIETKTTETEHIEQNIVSDSVADIVNEINLSET
                     SPKKKLPANKIIFSALYLFLVFFGVVGIPIAPFLAVPLTAWSLYKLYKLFRK"
     gene            complement(5401..5781)
                     /locus_tag="ACL29Z_001014"
     CDS             complement(5401..5781)
                     /locus_tag="ACL29Z_001014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000170931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ImmA/IrrE family metallo-endopeptidase"
                     /protein_id="HGR0069339.1"
                     /translation="MTLAKLCEEYQVELCLFDGSNWHSSGFYNPDTNVLAIDHNLAPE
                     QQIQVALHELGHKDHTRSEYQNARLRCENEADRNMIHHLVKDALESLDDPTEFDYLKF
                     MSYYNLKTMTNEVMVKEEYLALVN"
     gene            complement(5794..6057)
                     /locus_tag="ACL29Z_001015"
     CDS             complement(5794..6057)
                     /locus_tag="ACL29Z_001015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000285964.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008657 - DNA topoisomerase type II
                     (double strand cut, ATP-hydrolyzing) inhibitor activity
                     [Evidence IEA];
                     GO_function: GO:0042803 - protein homodimerization
                     activity [Evidence IEA];
                     GO_process: GO:0030541 - plasmid partitioning [Evidence
                     IEA];
                     GO_process: GO:0051290 - protein heterotetramerization
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="HGR0069340.1"
                     /translation="MYRLDIDKKALKQLKKLDTPTRKQILSWLAKNIENTTNPRQHGK
                     ALKANLAGYWRYRVENYRIICDIQDDKLVVLAVEIAHRRDVYK"
     gene            complement(6057..6290)
                     /locus_tag="ACL29Z_001016"
     CDS             complement(6057..6290)
                     /locus_tag="ACL29Z_001016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863055.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0069341.1"
                     /translation="MTITINFTEKNSYITDYLTKHGIDTTTMDFDDFMVLMEDIEDAR
                     AADQAYMEYLADPATYTMDEVLDELGLSREDIA"
     gene            complement(6290..6658)
                     /locus_tag="ACL29Z_001017"
     CDS             complement(6290..6658)
                     /locus_tag="ACL29Z_001017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000464160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HGR0069342.1"
                     /translation="MFVAFDKIKELADKQGISINILEEKLGYGTNTLYRLKRSNPSSK
                     VLKEIADYFNVSADYLLGRTDNPAIAGSDEFAQVNGQIIDLRKAAANTMLFDGKPLNE
                     DDIDFITSVLSAHFKSKGER"
     gene            complement(6964..7446)
                     /locus_tag="ACL29Z_001018"
     CDS             complement(6964..7446)
                     /locus_tag="ACL29Z_001018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0069343.1"
                     /translation="MKSSFFHYLKEIILYGVLVPILTVIVGFHLFTTFYPISDSLLTD
                     FLKAFTEQRILAIVFVLILCFIFFGSIYYCISCGRNRKLIPDKVYTQITTYISSVGLG
                     TAVIAVATLTLTELQFSILTGWIAFIALLLPLLKFKVQYSTYQSSDNVAQKTTENKAN
                     "
     gene            7501..7704
                     /locus_tag="ACL29Z_001019"
     CDS             7501..7704
                     /locus_tag="ACL29Z_001019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000032097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HGR0069344.1"
                     /translation="MSKELKIIKAKIKTRLIELDMTQAELAKQVSVTSSVISELLKYG
                     KGSDYVKEKVVDILGIENPWENS"
     gene            7721..7918
                     /locus_tag="ACL29Z_001020"
     CDS             7721..7918
                     /locus_tag="ACL29Z_001020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001066214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0069345.1"
                     /translation="MNNAAQKVTRIDKDAWEIATELANEYGVSICHIISESVRYCAEN
                     AEFKEMDVVVKRLVVGSKVLE"
     gene            7929..8090
                     /locus_tag="ACL29Z_001021"
     CDS             7929..8090
                     /locus_tag="ACL29Z_001021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001002946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0069346.1"
                     /translation="MNELVWFYFVVIINLIIGFATYYASKRDRKKRINEYKKIQDDEL
                     ERIRNKFNL"
     gene            complement(8085..8510)
                     /locus_tag="ACL29Z_001022"
     CDS             complement(8085..8510)
                     /locus_tag="ACL29Z_001022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000456432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0069347.1"
                     /translation="MDYQILIQPAISVILAIISGLWSYIASKANNKAEIEKQAKEHSH
                     IVEKLEKEFHYQIDTLKQQHTLELEKVKQAHELRLQELEKVSQIDTETDKAMKMNDLI
                     YKTFTGEVDLDKALKLADKANNHKQKLNKKFIQKTSKKS"
     gene            8564..9274
                     /locus_tag="ACL29Z_001023"
     CDS             8564..9274
                     /locus_tag="ACL29Z_001023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001002358.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ORF6C domain-containing protein"
                     /protein_id="HGR0069348.1"
                     /translation="MNEIFNFHGQEVRTLTIDDEPWFVGKDVADILGYSKARNAITLH
                     VDEEDALKQGIPTSGGTQDMLIINESGLYSLILSSKLPQAKEFKRWVTSEVLPAIRKQ
                     GGFIREDLDEDAFIALFTGQKKLREQQATMLEDIDYLKSEQPIHPSYAQSLLKKRKAR
                     VVACLGGIDSPAYADKVFAQSVFRQAEIDFKDHFNISRYDLLPKKHADAALAYWMTWE
                     PSTNTKMKIMKLNSFDDV"
     gene            9288..9545
                     /locus_tag="ACL29Z_001024"
     CDS             9288..9545
                     /locus_tag="ACL29Z_001024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000370958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HGR0069349.1"
                     /translation="MDNVLLSLSEWIKSIIKDTITRLVEIEKDSDHYPELMDVNTTCE
                     FLGIKYATFSDNYRYLKGFPKELPGKKWSKRAIKEWLSNQI"
     gene            9631..9951
                     /locus_tag="ACL29Z_001025"
     CDS             9631..9951
                     /locus_tag="ACL29Z_001025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000462832.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0069350.1"
                     /translation="MFEPPILDQLMGVGALLLGFAGACRHIKLQEQRKEEERREEQEF
                     ASMIIQGYNHAYERGREAERQEIRKNIRRPFKGFTYDNEPPQGLRPEPLALPEPKQSA
                     IRLL"
     gene            9967..10263
                     /locus_tag="ACL29Z_001026"
     CDS             9967..10263
                     /locus_tag="ACL29Z_001026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001865133.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0069351.1"
                     /translation="MEELIESLDNLIMIVKELEGRESTSRHFITIWENDYKNLLLVKE
                     YLTDYEKLAKDYRYVTLKNKLLKIEKMELEGRHIYEDMRMKYRANRRKWGARYV"
     gene            10256..11062
                     /locus_tag="ACL29Z_001027"
     CDS             10256..11062
                     /locus_tag="ACL29Z_001027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001289771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage replisome organizer N-terminal
                     domain-containing protein"
                     /protein_id="HGR0069352.1"
                     /translation="MSEIKWIKITTDIFDDEKICLIDALPDPDAILVIWFKILTLAGK
                     HNSNGLLMMTDKVHYTDEMLATIFRRPLNTVRMAIGVFEQFGMIEIIDGIISLPNWEK
                     HQNVDGMEKIKEQTRNRVAKYRKKQKNLALGNVTGNVTVTDGNALEEDKDKNKNRLDK
                     DKNKKRITTTSSGSEENILELFQSEFRRLLSGFEIEEINHLLNENDVDLVKEALKTAI
                     NSGKPNIKYIGGILRNWQMNNVTTVEQVRQSEKKNKDKKEEQEAKDEWGY"
     gene            11202..11972
                     /locus_tag="ACL29Z_001028"
     CDS             11202..11972
                     /locus_tag="ACL29Z_001028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000228202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HGR0069353.1"
                     /translation="MVDNVFEEIALSYRRNTEQQEEFCEKHNIPLIKILRTESVVCRM
                     CESERIHEENQERVNELANAENERERKYYLEKFSLYDEVLKNATLDNFETPTEKEAEK
                     LAFAKRICREWSEGARNNIVLQGEAGTGKSHLAFAMVKALSEYTKEIAIFINVTDLLM
                     KIKADFSQEEFLVNKIASAKFLVLDDLGMEKDSEWSFTILYNILNKRSNTIITTNLIS
                     ADIQKRYGRPFMSRLMKGVDKDHLMVFNDLTNKRKQYF"
     gene            11987..12181
                     /locus_tag="ACL29Z_001029"
     CDS             11987..12181
                     /locus_tag="ACL29Z_001029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000470305.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0069354.1"
                     /translation="MFILKHGTREDKPFLRSAIISVTGLDISCSEEKKAMRFISRAAA
                     VQVGKALRGSFGNFYPVEVE"
     gene            12181..12855
                     /locus_tag="ACL29Z_001030"
     CDS             12181..12855
                     /locus_tag="ACL29Z_001030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000975313.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific DNA-methyltransferase"
                     /protein_id="HGR0069355.1"
                     /translation="MMKFLNGDCMDIMKQYPDNYFDLAIVDPPYFSGPEKRKFYGRKI
                     SPIGVSRLYGEISEWKIPNRDYFDELFRVSKNQIIWGVNYFDYSFGSGRIVWDKVNGQ
                     SSFSDCEIAYCSYHDSTRLFRYMWNGMMQGKSISEGHIQQGNKALNEVRIHPTQKPVN
                     LYLWLLQTYAKEGDKILDTHVGSASSLIACGELGFDYVGCEIDKSIFNLAQQRLDAYE
                     KQLKLF"
     gene            12865..13083
                     /locus_tag="ACL29Z_001031"
     CDS             12865..13083
                     /locus_tag="ACL29Z_001031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000891962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0069356.1"
                     /translation="MLELYFVYNGHCKFYLGRFDNVDDLIEQMEDHQWAFSAITHPRF
                     QKHIGQRTTRFDYGSKDCYYLATFSGGK"
     gene            13083..13208
                     /locus_tag="ACL29Z_001032"
     CDS             13083..13208
                     /locus_tag="ACL29Z_001032"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0069357.1"
                     /translation="MAKNILMDLAFENFHKCMGISDLVGGKKHGWSNLSGNSSLC"
     gene            13168..13335
                     /locus_tag="ACL29Z_001033"
     CDS             13168..13335
                     /locus_tag="ACL29Z_001033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000233204.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0069358.1"
                     /translation="MVGVTYQEIHLFVEFLKEQYGQGRPDYIEALNDLDGLVEVSYRE
                     AIERFLEDEVR"
     gene            13503..13820
                     /locus_tag="ACL29Z_001034"
     CDS             13503..13820
                     /locus_tag="ACL29Z_001034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000969666.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0069359.1"
                     /translation="MMEELKRKVNEVYNWTVEDGKPQPPKQDLPQAVKDRADYFWEMA
                     EDGMTFMGAMECIFADEKPTDYDLGATKGWLPKSKEFDDWVGYSPSMAQVVIAVYLIY
                     GGN"
     gene            13822..14352
                     /locus_tag="ACL29Z_001035"
     CDS             13822..14352
                     /locus_tag="ACL29Z_001035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001021765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1642 domain-containing protein"
                     /protein_id="HGR0069360.1"
                     /translation="MNIKALIKKYEELWNEHSPFYEPVPYTSMVELFLKELKQLDEPQ
                     KVKIPQFVADWIEVCKEHLTTSLYTAMTPNFMKENNQSFDLILWIKKASNQDLFARAW
                     LDGYEVEKEKRYLVKIKGNIKENMLVYGELLERYFFTKSFSLDDAIYSHTRKELENAK
                     IGWVFDCEGFEIEEVE"
     gene            14352..14639
                     /locus_tag="ACL29Z_001036"
     CDS             14352..14639
                     /locus_tag="ACL29Z_001036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000194860.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0069361.1"
                     /translation="MTQTLEEGMKNQSKCIKVPREIRPFDIGYRIVNKYGQALALRNG
                     ASIFDLPFLAEKAIEKEFGKNDPDFDIGKHSVEEVAIVNLSKFHSYFEERV"
     gene            14670..15752
                     /locus_tag="ACL29Z_001037"
     CDS             14670..15752
                     /locus_tag="ACL29Z_001037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000670043.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA cytosine methyltransferase"
                     /protein_id="HGR0069362.1"
                     /translation="MKFLDLFAGIGGFRLGMESAGHKCIGFCEIDKFARESYKAIHNT
                     KGEIELHDITAVSDESIRGIGSVDIICGGFPCQAFSIAGNRRGFEDTRGTLFFEIARF
                     ASILRPKYLFLENVKGLLNHENGVTFETIISTLDELGYNVEWQVLNSKNFGVPQNRER
                     VFIIGHLRREHTRRIFPLSGKNQSTSNQSVMKIGNINPSGNGMNGEVYQADGLAPTLT
                     TNKGEGQKIAIKSNTIKQFGVLQPNFNQCGVVYETDGIAPTIRAYQGGGLEPKIIQRG
                     HGYNKGGEHNIAPTLTSNSYHENNHLSDGFRIRKLTPRECWRLQGFPDWAFDKAQEVN
                     SNSQLYKQAGNSVTVNVIAAIAKELS"
     gene            15749..16132
                     /locus_tag="ACL29Z_001038"
     CDS             15749..16132
                     /locus_tag="ACL29Z_001038"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0069363.1"
                     /translation="MNTIEKVKQWFIDRDLENGRVVGLMVLSSKRRIYKMKRLGIIIG
                     AVFVIVVSPFVVQYGWNEIITTIVPVGKITVWQALGMDALLSFIWPVLSSKKESEEDY
                     SYAVKSSISKIITCAFLIWLASLFI"
     gene            16144..16554
                     /locus_tag="ACL29Z_001039"
     CDS             16144..16554
                     /locus_tag="ACL29Z_001039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000612382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YopX family protein"
                     /protein_id="HGR0069364.1"
                     /translation="MIPKFRGLSIDEKSKGEWQYGHLIEDRGRAFIINEVVEANEQYI
                     TIGSWCPVNPATLGQSTGLRDKNGKEVFIGDIVKCTRGCLHEVYLEKEYGGTYIGGMP
                     AVYLKGFGDGYAWTEYEEIIGNVYENPELLEVNE"
     gene            16691..17092
                     /locus_tag="ACL29Z_001040"
     CDS             16691..17092
                     /locus_tag="ACL29Z_001040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000736386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HGR0069365.1"
                     /translation="MKKLSDEDLKTLDRELFKFQNIQRTIDLRRLELETRNPDAQSGP
                     SVGISKPTETIAVRIADDPTLKFLEGFKAIINKLLINLVDEDKEIFNLRWRYPQLRWE
                     EIAEQKFMSKATIYRRRRIILEQYAILKGEL"
     gene            17280..17822
                     /locus_tag="ACL29Z_001041"
     CDS             17280..17822
                     /locus_tag="ACL29Z_001041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000397549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HGR0069366.1"
                     /translation="MEFVSPIKDNDDIQAMKDYLREWNEMYYMLFITGLNTGLRVGDI
                     LTLKVKDVQGWHIKLRERKTGKQITRRMTKELKKEMRRYVEGKPFHHFLFKSRQGQNK
                     AITRERAYQIIHEAAEELGIDNVGTHTMRKTFGYKYYNKTKDVGTLQKMFNHSSPAIT
                     LRYIGIEQAELDDALRNFVI"
     gene            18199..18519
                     /locus_tag="ACL29Z_001042"
     CDS             18199..18519
                     /locus_tag="ACL29Z_001042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000282427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HNH endonuclease"
                     /protein_id="HGR0069367.1"
                     /translation="MYNKPIRPSLKSKKWEKFRDRIMRKHDYLCQESLRYGISVQAEM
                     VHHIFPVSEYPELEFVEWNCLPLTNKKHNTFHDRVNDRVINQGLYWQKKRKKEFLNFF
                     KNEK"
     gene            18656..19048
                     /locus_tag="ACL29Z_001043"
     CDS             18656..19048
                     /locus_tag="ACL29Z_001043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001118284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="P27 family phage terminase small subunit"
                     /protein_id="HGR0069368.1"
                     /translation="MAKPITAKSIKSKVVKQMKDLGTYRKEFEMIIDIFAGMLYQYQK
                     LAQDYVDMGYPVTDTYVNKAGAENERKVPILTAMEILRKDILSYSNQLMMNPKSLGEV
                     VEQEGESVLTEVLKFKNEIKKKRVTGNG"
     gene            19041..20771
                     /locus_tag="ACL29Z_001044"
     CDS             19041..20771
                     /locus_tag="ACL29Z_001044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001845577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="terminase large subunit"
                     /protein_id="HGR0069369.1"
                     /translation="MGNLDKAKKYAQHVLTHREEHCEENILAAERFFRDLENPTFEMD
                     EDMVDFVIHFIENVIVHQQGDDMFAVSIRNKPLLLQPWQHFVVVNLFGFYYKGTNERR
                     FKEALIMLARKNGKTSFTAAIALAYQILDTDSGSKCYIVANSVKQAMEAFGFLRFNVE
                     RWNDKNIRIKDNNQEHSITANFGDEGSFFIQALANDESRLDSLNGNVIILDEAHTMRN
                     SKKHGLMKKTMSAYRNSMLFVISTAGDIPTGFLANRLKYCQKVLKQLVTDDSFFIFIC
                     KANQSADGDVVNYLDENILKMANPSWGVTVSLKALKEEAEQAMNDPQTRNEFFNKTLN
                     IFTNSMNAYFNPDEFIASDSCYDWSLEELARLPIRWYGGADLSRLHDLTAAALYGVYH
                     DGEKDVDICITHAFFPRINAQKKANDDGIPLFGWQSDGWLTMSNTPTVLYDDIVKWFI
                     KMREKGFKIAAVGMDRKFGREFLTKMKQARFKMIDQPQLFYLKSEGFRRIEFKVKNKE
                     FYYLHSDAYEYCVSNVRAIEKVDDAVQYEKLDGDGGTARIDLFDASVFACIQALANLG
                     KGGDVMRFFD"
     gene            20779..20997
                     /locus_tag="ACL29Z_001045"
     CDS             20779..20997
                     /locus_tag="ACL29Z_001045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001002923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0069370.1"
                     /translation="MNEIVLSEHEINLLINKGRVKVILNGEVVTIRQRHMKNLMAETV
                     KWEKQVIDVSQNIVRNKHFDSLFQNTFR"
     gene            21015..22217
                     /locus_tag="ACL29Z_001046"
     CDS             21015..22217
                     /locus_tag="ACL29Z_001046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000510804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0044423 - virion component [Evidence
                     IEA];
                     GO_function: GO:0005198 - structural molecule activity
                     [Evidence IEA];
                     GO_process: GO:0019068 - virion assembly [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phage portal protein"
                     /protein_id="HGR0069371.1"
                     /translation="MGIFEKFWKRNKPSKSINMLSHSDLGLSNLMDSYVPLARNPDVV
                     TAVNKIADLVSNMTIHLMENTDKGDIRIRDGLARKIDINPCKHMTRKSWIFKIVRDLL
                     LYGDGNSVLHVEYEPVTDYISNLRPFPMREVSFQTDKDSYVISFRGEEYSPDEVVHFV
                     INPDPDILYIGTGFRVTLTDVVQSLNMATKTKKSFMNGKNIPSLIVKVDSSSAELDSE
                     QGRERIAEKYLSTSRVGAPWIVPEALLDIQQVKPLSLTDIALNESVELDKRTVAGLLG
                     VPAFILGVGEFNKTEYNNFVNTTVMSIATTITQTLTRDLLLSSNRYFKLNPRSLFSYN
                     ITELSAVAQQMANSAAMRRNEWRDWLGMAPDPEMEELIVLENFLPQEKLGDQNKLKGG
                     EEENAKAK"
     gene            22201..22776
                     /locus_tag="ACL29Z_001047"
     CDS             22201..22776
                     /locus_tag="ACL29Z_001047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001172113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005198 - structural molecule activity
                     [Evidence IEA];
                     GO_function: GO:0008233 - peptidase activity [Evidence
                     IEA];
                     GO_process: GO:0019068 - virion assembly [Evidence IEA];
                     GO_process: GO:0019082 - viral protein processing
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HK97 family phage prohead protease"
                     /protein_id="HGR0069372.1"
                     /translation="MQKRNSYRATQFQTREEESGDLVLSGYFIKFDEETELWRGYHEV
                     IKRAGVEKAVTDADIRALFNHDDSLVLGRTGNGTLTLGVDDVGLFGDIIINKDDPQAV
                     GAYARVKRGDVIGCSFGFIPVKIETEEREDGSYLDTVLELEIFEVSPCTFPAYPQTEI
                     AARQKDFESQKRANREALDKRKKEIKEKFKL"
     gene            22773..23939
                     /locus_tag="ACL29Z_001048"
     CDS             22773..23939
                     /locus_tag="ACL29Z_001048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006150459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0044423 - virion component [Evidence
                     IEA];
                     GO_function: GO:0005198 - structural molecule activity
                     [Evidence IEA];
                     GO_process: GO:0019068 - virion assembly [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phage major capsid protein"
                     /protein_id="HGR0069373.1"
                     /translation="MNKALIFGARMRAKATKVVELEETIEELNKRSVVELEKLDRAKN
                     DEEVLAVEKTVDGLQREIEEKEAEKVQLENEIDELDKQIKEQNRKAPTPGKMEERGGK
                     TLGQREAFNHYLRTKEARADGFKSAEGEAIIPVELMTPKEAKQDKTDLTSLVNIVNVK
                     NASGKWSVVKLTDQAMNTVEELEENPELAKPTFTKVNYEIKTRRGHLPVSQEFIDDAD
                     YDVMGLVAKQTKNQERITKNKEIAKVLKTATSKSAAGLDGLKDILNVELKTYYNATIV
                     CTQSMFAALDKIKDKDGRYMLQTDITSPTGYKFAGRVIVVYPDDIIGESKGDLKAFIG
                     DVGEFATLFDRAQTTVKWQDDKIYGQYLGTANRFDVKKVDEAAGFYVTYTDAVG"
     gene            23951..24241
                     /locus_tag="ACL29Z_001049"
     CDS             23951..24241
                     /locus_tag="ACL29Z_001049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000120767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0069374.1"
                     /translation="MRYKVIRPFKDLADPENHDYAVGDIFPREGYEPTDSFTNGLLTG
                     ANTAGSIFLEVLGDDEPKKPAPETKEVKEEPAVEQEETVEETAEESAEEVEE"
     gene            24244..24525
                     /locus_tag="ACL29Z_001050"
     CDS             24244..24525
                     /locus_tag="ACL29Z_001050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000371962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage head-tail connector protein"
                     /protein_id="HGR0069375.1"
                     /translation="MDQGQLLELLKLKLGISTDLRDKPLKKIISSVITELTDNLGIEL
                     VGERADHEMFIVDYAAYRYEGGVDMPRHLQWRLHNLQIASKKEVKNVES"
     gene            24512..24811
                     /locus_tag="ACL29Z_001051"
     CDS             24512..24811
                     /locus_tag="ACL29Z_001051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000267058.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0044423 - virion component [Evidence
                     IEA];
                     GO_function: GO:0005198 - structural molecule activity
                     [Evidence IEA];
                     GO_process: GO:0019068 - virion assembly [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phage head closure protein"
                     /protein_id="HGR0069376.1"
                     /translation="MWNHEITLISKKVTGKDKLLQPISEDVEVTLLCRKKRVTRSEFY
                     QANQVGLKPSLVVEIRNFEYENQELAKFEGKQYHILKTYPIDSEILELTLSEVLK"
     gene            24808..25155
                     /locus_tag="ACL29Z_001052"
     CDS             24808..25155
                     /locus_tag="ACL29Z_001052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000063887.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HK97 gp10 family phage protein"
                     /protein_id="HGR0069377.1"
                     /translation="MSNDLADLIAKELAAYSDEVTEEVDKIAEQVADETVDELKETSP
                     KRYGKYRRSWKKKKLANGSFVVFNAVASLTHILENGHLSRNGGRVAGIVHIKPAEEKA
                     IQNFEKRIKEIGK"
     gene            25152..25475
                     /locus_tag="ACL29Z_001053"
     CDS             25152..25475
                     /locus_tag="ACL29Z_001053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001847815.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0069378.1"
                     /translation="MKLSDFAAILEQANLPVTYRAFKIGNAPDLPYLVYYESSPVINS
                     ADNTVNHQIKSVTVELAFESKDEDLEERLEELWANHKLFFEVQEETFIETERLYVKSY
                     TVYLY"
     gene            25487..26065
                     /locus_tag="ACL29Z_001054"
     CDS             25487..26065
                     /locus_tag="ACL29Z_001054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000191275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005198 - structural molecule activity
                     [Evidence IEA];
                     GO_process: GO:0019068 - virion assembly [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="major tail protein"
                     /protein_id="HGR0069379.1"
                     /translation="MTQENKVTFGLENVHIAPIKTLAADGVITYGDVFRFPGAIELIL
                     DTKGETTPIKADNKDYHFMNSNEGYEGKLKIPHIIDEFATKILGEIKDPQTGVMTEKA
                     DASLTEFAMMFQFEGDKNKTRYVMYYCFASRPSLGSKTKNGTSTNERELSFKASPRPL
                     DTVVKRSITSADDKDAYDNWFKKVYEPTAVVA"
     gene            26077..26496
                     /locus_tag="ACL29Z_001055"
     CDS             26077..26496
                     /locus_tag="ACL29Z_001055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003047255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0069380.1"
                     /translation="MRKIVLVGDQEYELGTNGYTPIAYKQQFGKDYFQDLFSMLKNQS
                     FMNELNKLETDKELTATDIDISMLSDFDMTFFNRLFWTFAKSANPHIKPYEQFFMEME
                     VFPIQEVGPVLMEMLNASMTTKKHQMNQNQLAKKSSQ"
     gene            26773..29532
                     /locus_tag="ACL29Z_001056"
     CDS             26773..29532
                     /locus_tag="ACL29Z_001056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000918318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail tape measure protein"
                     /protein_id="HGR0069381.1"
                     /translation="MAGNIKGIKIEIDGDTQPLQKALKNVNKAATDASQELRQIDKAL
                     KFDTGNVTLLTQKQEVLQKQVSTTKEKLETLRQAQSQVEQQFKNGDIGADQYRAFQRE
                     VEVTQNVLKGYEGKLANVNQALAENGNATKSNQTQLKELQNEQSQLASEMTKVTSSFK
                     LQESALGSNASEAERNALAQKKIGAQSEIVSKQISNLEQQLEITKKEFGENSTQANRM
                     EAELNQAKTAFNHLNDEMKGTKSAADSTQESLSEISRNLRAELLQQFSEKLSAISEKL
                     VEVGKEALEAAAQMQASNAQFTTVFGDMETQAREALNAIGQEMDIVPERLQGSFTQMA
                     SFAKTSGLDTAEALDLTSRATRAAADGAAFYDKSIESVTESLQSFLKGNFANDAALGI
                     SATETTRNAAANKLYGKSFKDLSEAQKQLTLLQMVEDGNKLSGALGQAARESDGLENV
                     MGNLKQAGTNALSAIGQPLLEMMIPVFQTLATIVKGVAELFSSLPAPVKDFVVILGTV
                     VTAVGVIAPIFLSLQALAEFLKISIGEMIIAALPIIGTAIAIAAAVAAIIVIVKYLWE
                     TNEGFRDAVTTVWNAILEVINAVVSEISNFVMSIFGTVVAWWTENQELIRASAETVWN
                     AIYTVISTILEILGPLIQAGWDNIQLVITTAWEIIKTVVETAINVVLGIIQAVMQIIN
                     GDWSGAWETIKGVFSTVWQAIQSIVQTIFSAIQSYISNILNGISGTVSNIWNSIKDTV
                     SNVLNAISSTVSSVWEGIKSTISSAINGARDAVSSAIEAIKGLFNFNISWPHIPLPHF
                     YVSGSANPLDWLSQGVPSIGIEWYAKGGIMTKPTIFGMNGNNIMVGGEAGNEAVLPLN
                     DKTLGAIGRGIAQTMGGTSPTINITITGNTVREEADIIRIADEVAQRIADELQRKTQL
                     RGGFT"
     gene            29529..30251
                     /locus_tag="ACL29Z_001057"
     CDS             29529..30251
                     /locus_tag="ACL29Z_001057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006150465.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HGR0069382.1"
                     /translation="MIKHNELVIDGVRTSSFPFKVIVHDSPSIALGESKTALLEHGGI
                     SGAIVQTNKHRELVKKTYTIYLVKPTEEQMNQFMSLFIREKFWLESERVKTTRLWCYK
                     VNVSDLEEVQPGLYMTKATFTCHPTKHFKVTDTQRLTRSGTLTVQGSALAFPKITIVG
                     QSASETSFTIAGQVIRLEKLSESLVMVNNPDNPSFKTTTGKPVKWSGDFITVDPAKVK
                     NIGVVLGPGIQSIEIETVWGWA"
     gene            30252..>32137
                     /locus_tag="ACL29Z_001058"
     CDS             30252..>32137
                     /locus_tag="ACL29Z_001058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000966215.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005198 - structural molecule activity
                     [Evidence IEA];
                     GO_process: GO:0016032 - viral process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail spike protein"
                     /protein_id="HGR0069383.1"
                     /translation="MLYLLNKDVRTVRWNGEPLHEATSAIVKEIMNSDFTLTVKYPIS
                     DSGIYQLIQEDMLIKAPTPVLGAQLFRIKKPVEYNDHLEITAYHISDDVMQRSITPVS
                     VTSQSCGMALSRMVQNTKTALGDFSFNSDIQDHRTFNTTETETLYSILLDGKHSIVGT
                     WEGELVRDNFAMTVKKSRGENRGVVITTHKNLKNYQRTKNSQNVVTRIHAKSTFKPEG
                     AEKETTIRVTVDSPLINSYPYINEKEYENNNAKTVEELQKWAQSKFSNEGIDKVSDAI
                     KIEAYELDGQVVHMGDTVNLKSWKHNVDAFKKAIAYEFDALKEEYISLTFDDKAGIGG
                     SRASGGLSSAADAILGVTESAQEIALDKALQNADLDFDHKAGLLRQEISDDIELAKAK
                     AEEVKRELSDTINQRFNSFDNGPLKETKRKAEEALRQAGASSSLAQEAKRIGLDSVAR
                     LEAFKSQTTSAQTALSGDLDALKRTIVNDIRPKQAQAEAEIAKQAEALSRTKNELAGA
                     STLLAQEAKRIELDSVARLEAFKSQTTSAQTALSGDLDALKRTIANDIRPKQAQAETE
                     IAKQVEALSRTKNELAGVKSAQATYEETTTRRLSELTNLANGKASKSELTQTAEELAS
                     RIASV"
BASE COUNT        10150 a         5370 c         7278 g         9339 t
ORIGIN      
        1 taatccgcca tagctcagtt ggtagtagcg catgactgtt aatcatgatg tcgtaggttc
       61 gagtcctact ggcggagtaa tttagttaag aggtttagac ctctttttta ttatgtaata
      121 ataatctatt tcgtgttata gtaaaatgaa ccaaaaatag tggctctttg tcaactgtag
      181 tgggttgaag aaaagctaag cttgagaaag gacaaatttc gtcctttctt ttttgaagtt
      241 ttcaaagttc ctaaaaccaa aggcattgta cttgataagt ttgatgagat tattggtggc
      301 ttccagtttg gcgttggaat aaggtaattg aaggccgttg acgatttttt ctttatcttt
      361 gaggaaggtt ttaaacagag tctgaaaaag aggtggaaaa gcaagagctg atagagatta
      421 tagtggtgtt tcaagtcttc ggaatagctc aaaagtttat ctagaatttc tttattagtc
      481 aagtgcatac gaaaagtagg gcgataaaat cgtttatcac tcagtttctg actatcttgt
      541 tgaatgagct ttcagtatcg cttgatagcc ttgtattcat gggatttcgg atgatggctt
      601 gtgttctgct ctcaagaaca gttatgatat tgagcttatc aaagtcttga gcaataaagc
      661 tcatctccat ctcccgattg aaacagtcac tccccggact gtttcaacgt cctaggacat
      721 aatctcagga agacgcgaaa aatcatgctc aaagtgaaaa tcattgatct tgcgaatgac
      781 agttgaagtt gaaatagaca actgatgatc aatgtcggtc atagaagtct ttttaattag
      841 cttctgagca atcttttggt tgatgataca aggaatttga tgattcttct tgacgataga
      901 agtttcagcg accctcattt ttgaacagtg atagcactta aaacggcctt ttctaagaag
      961 aattctagtt tgaatttttt atactagaaa atcagaacca taatacctat ataaaaatat
     1021 tatagttcta ataggattta cccaaaagtt ttaaggcggt ctttttagaa ctttaatcgt
     1081 ttgaaattta ggtagcaaat ttgtttctat tctgtcaact tttcctattt ttatcttgtt
     1141 gagcctggta ttttaacaat tcaggaattg atagtgaatg tgtaaaattt tttgttagaa
     1201 taagtttata aaaaagaaaa ggagtatttg attatgttac aaaaaattta tgagcagatg
     1261 gctaatttct atgatagtat tgaagaagag tatggtccta catttggtga taattttgac
     1321 tgggaacatg ttcattttaa atttttaatt tattatttag tgagatatgg cattggttgt
     1381 cgtagggatt ttatcgttta ccattatcgt gttgcttatc gtttgtatct tgaaaaattg
     1441 gtaatgaatc ggggttttat ttcttgttga ggtaatttta gtaaatttcc gaactaattt
     1501 acttttttat ggaaagataa tagtaaatag ctagtaattt ttctaaatca ttttttaata
     1561 gttggaaata gcaaatcttt ctattgtttc ttcttgataa aaaggcgatt ttttattata
     1621 ataaattgta agatataatt gcaggtgaga gtcctgccat gtatgtgaga aaggaagagc
     1681 ctgagggctc agacaagatt atgacttcag ttgttgttgt aggtacccaa tggggtgatg
     1741 aaggtaaagg gaagattaca gacttccttt cagcgaatgc agaagtgatt gcacgttacc
     1801 aaggtggtga taatgctggt cacacgattg tgattgacgg taagaaattt aagttgcact
     1861 tgattccatc tgggattttc ttccctgaaa aaatatctgt cattgggaat ggtatggttg
     1921 taaatcctaa atctcttgta aaagagttga gctatcttca tgaggaaggt gtaacaactg
     1981 ataacttgcg tatttctgat cgtgcgcatg ttattttgcc ttatcatatc gagttggatc
     2041 gcttgcaaga agaagctaag ggcgacaata agattggtac gacaattaag ggaattggtc
     2101 cagcttatat ggacaaggct gctcgtgttg gaattcgtat tgcagatctt ttagataaag
     2161 atattttccg tgagcgttta gaacgtaacc ttgctgaaaa gaatcgtctt tttgaaaaat
     2221 tgtatgacag taaagcgatt gttttcgatg atatttttga agaatattac gaatatggtc
     2281 aacaaatcaa gaaatacgtg atagatacat ctgttatctt gaatgatgcg cttgataatg
     2341 gcaaacgtgt gctttttgaa ggtgcacaag gtgttatgct agatattgac caaggtactt
     2401 atccatttgt tacgtcatca aaccctgtag ctggtggtgt gacaattggt tctggtgtcg
     2461 gtccaagcaa gattgacaag gttgtaggtg tatgtaaagc ttatacgagt cgtgtaggag
     2521 atggtccttt cccaactgag ttgtttgatg aagtgggaga acgtatccgt gaagtgggtc
     2581 atgagtatgg tacaacaact ggtcgtccac gtcgtgtagg ttggtttgac tcagttgtga
     2641 tgcgtcatag ccgtcgtgtt tctggtatta ctaacctttc tttgaactct attgatgttt
     2701 tgagcggttt ggatactgtg aaaatctgtg tggcctatga tcttgacggt caacgtattg
     2761 actactatcc agctagtctt gagcaattga aacgttgcaa gcctatctat gaagagttgc
     2821 caggttggtc agaagatatt accggagttc gcaatttgga agatcttcct gagaatgcgc
     2881 gtaactatgt tcgtcgtgtg agtgaattgg ttggcgttcg tatttctact ttctcagtag
     2941 gtcctggtcg tgaacaaaca aatattttag aaagtgtttg gtcctaagag atttttaaga
     3001 tttgtttaag ataggtcggg tatactatag acggttacaa gaagacctcc taacttgttg
     3061 taacaaatat cctaaacttt tctttttcat aataatctcc cttaactcca ccgaatcagg
     3121 tggagttttt tagctctatt tcaggctttt ggggactatt ctaaaaataa tttttcgata
     3181 tttttcggta tttttcggat tttggtcggg gaattggcgg ggactttttt agcgaatatg
     3241 actaagaaat aggtctgttg tcgcttcagc aagttcgtcc tctacttgat tgtaacgatc
     3301 cgtcatataa acctttgtat gccccagcgc ctggcttaat tgttcaagcg gaacccctgc
     3361 aataatgctt tgagtcgtga agaagtggcg catcatgtga ggtgttacat gcaatcctgt
     3421 tgcttcattc actagattga agtttctatt tagctgattt ggattgatga gaccaccttt
     3481 ctcgttgata gttatataat ccttgtgctg ttccttgata attcctaact ttcgcttaat
     3541 cttagaagct tcagctatca gataatagat caggtctgtt ccgatatcat caaggcagac
     3601 atatcgctct gaatccttcg ttttaagccc tcctttccct tttaaggtct ggttgcttcg
     3661 actgtctcta agatgcagta tagcccgtcc gctgtcgttc tgagtgatgt ccattggacg
     3721 caatccaaag acttctcctc ttctcaatcc aaaaattgtc agataggtca gagcgtagaa
     3781 ttgttttggc ataatctctt ctgcctttgc tatccaagtc ttgaactctt tgagagtcac
     3841 tttcttgttt gcagcaggga tatcactctg gccgatgaaa acacctttca agcgatttga
     3901 gagcagatta ccatttttca cggcatcatt cagcaatgcc atgaagctgg aattgagggt
     3961 ttgaacagtg tatctggtat ggttctgcaa cttttcagcg ataaatagtt catactcatt
     4021 tctatccaaa tttttaagca ggatagaacc aaactttgcc ttgatatggt tcttatagag
     4081 attgtcattg aggtagtagg aagtgtcatt ccagcgccct gttgacaatc tcttttcgga
     4141 atagatatcc caatattgat caagcgttag attcgtattg atacctaatt cttgttcttg
     4201 gatttgttgc tcaagctcta ccaaggctgc acgagcttga gggagagttg tgaaaccact
     4261 tttacttttt tctctttttt tacctcggaa gaaaaaagaa cgtctgacat agtaacgctt
     4321 gcctttagca gtctcatagt aatagatatt tgggtatttt gttttattat atttcattgt
     4381 attctccttg tttatcggct tctggacaag gtctaaacat tgagaatatt gacatcaccc
     4441 ctttcatggt gtaaaatagg gtatagaaaa gaggcctttt taatggctga ttttttataa
     4501 gggtaagctt cacaatcaaa ctttggcgag ggcgattgtg gggctttttt ttattttctg
     4561 aatagtttgt atagtttata caaactccaa gctgtcaaag ggactgcaag gaatggagcg
     4621 attggaatac caacaactcc aaaaaagact aagaaaagat acagtgctga aaatatgatt
     4681 ttattggcag gaagtttttt cttaggagat gtttctgaaa gattaatctc gtttactata
     4741 tcagcgacac tgtcactaac aatattttgt tcaatatgtt cagtttcagt tgttttagtt
     4801 tcaatagctt cagtttccgt aacttcttta ttggaaatgt tatcatcaat tatctcagat
     4861 gattcgctct gaattacttc tttttgtgaa gaatcaacaa tggtaaggta aatttcaaaa
     4921 ccaacatcca aatcattatt tgtgacaact ttttcttcat actcgtccca ttctttatat
     4981 gggccacctt ttatctctcc ctctattaca aagttatatt ttttattatc aaaatatttt
     5041 cgtattgttt tagcaatggt tgcaggaaca tatcctacat gattatcaaa tatcaaaact
     5101 tttatagcat taggatcata tctattatct atttctggaa cgagctcaat attgaaaaag
     5161 tctaaatctt gatatttgaa aactttcaga ccatattctt caagttcttc tctaagttcc
     5221 ttagttgata aattgctata gtactttgca tattctggga ttccgttatc ttcagcaatc
     5281 atattgcaag cttcttttac tgctttttta tattttgtca ctccagcgac tctgaataat
     5341 attttttcaa cagtcttttg catatatttc ccctctatat aaatatcttc aatgcaattt
     5401 ttaatttact aatgccaagt actcttcctt gaccatgact tcattagtca tagtttttag
     5461 attgtagtaa gacatgaatt tgaggtaatc aaactctgtg gggtcgtcta agctttctag
     5521 tgcgtctttc acgagatgat ggatcatatt cctatcagct tcgttttcac agcgtaggcg
     5581 agcgttttgg tactctgagc gtgtatggtc tttgtgtccg agttcgtgta gggcgacttg
     5641 gatttgttgt tcaggagcta agttgtggtc aatagcgagt acgtttgtgt ctggattgta
     5701 gaaaccgcta ctgtgccagt ttgaaccgtc gaagagacaa agctctactt gatattcttc
     5761 gcagagttta gcgagtgtca tagttctcct tcgttattta taaacatctc tgcggtgggc
     5821 gatttccacg gctaggacga ctagtttatc gtcttggata tcacagatga tgcggtaatt
     5881 ctctactctg tatcgccagt aacctgcaag gttggctttt agtgcttttc cgtgttgtcg
     5941 tggattggtc gtgttttcaa tgtttttagc aagccaggat aggatttgtt ttctggttgg
     6001 ggtatctagt tttttaagtt gcttgagagc ttttttatca atatctagcc gatacattaa
     6061 gcaatatcct ctcgagatag tcctagttca tccaagacct catccatggt ataagtagct
     6121 gggtcggcta aatactccat ataggcttgg tcggctgctc gtgcgtcttc gatatcttcc
     6181 atgagtacca tgaagtcgtc aaaatccatg gttgttgtgt cgataccgtg tttggttagg
     6241 tagtccgtga tgtaggagtt tttttctgtg aaattgatcg tgatagtcat tagcgttctc
     6301 ctttgctttt gaagtgggcg gatagaacgg atgtgatgaa gtcgatatca tcttcattta
     6361 gtggttttcc gtcaaataac atggtgttgg ctgctgcttt gcgtaagtct atgatttgtc
     6421 catttacttg agcaaattca tcacttccag cgatagcagg attatctgtc cgtccgagta
     6481 ggtagtcagc acttacatta aaataatcag ctatttcttt taaaactttt gaactaggat
     6541 tacttctttt taatcgatat aaagtattag ttccataacc aagtttttct tctaaaatat
     6601 ttatagaaat cccctgttta tcagctaatt cttttatttt atcgaatgct acaaacatta
     6661 atttttcaac ctttctaagc aaacgaaaaa taattttaaa atatttgtag aaaatagttg
     6721 acttatttag tcaaatgttt taaaataata ttcgtaagct aaagagttag cgaactagac
     6781 aactaaaaaa taaagcctta caaaactgat tggcgtccgt ttactgtagg taaaacttac
     6841 ttttagtagg tcttttctct atgtttttat tttaaaacat ttgactagag ttgtcaagaa
     6901 gttcgctaac tttttagata attttttaaa agaaaggggg agaggagaat ggtagagcct
     6961 ttcttaattg gctttgtttt cggtagtttt ctgtgctaca ttgtcgctac tttgataggt
     7021 gctgtattgg actttaaact tcagaagtgg caacaacaaa gcgataaaag caatccaacc
     7081 tgtaaggatt gaaaactgta attctgtgag agtcaaggta gcgacagcta tcactgcagt
     7141 ccctaaacct acagatgaaa tgtaagttgt gatttgtgta taaactttat caggtatcaa
     7201 ttttctattt cgtccacatg aaatacagta ataaattgaa ccgaaaaata taaagcaaag
     7261 aataagaacg aatacaatag caaggattct ttgttctgta aaagctttca agaaatctgt
     7321 taacagtgaa tcagaaatag gatagaaggt agtaaaaagg tgaaatccta cgataactgt
     7381 caaaatcgga actaggacac catataagat gatttccttt agatagtgaa aaaatgaaga
     7441 tttcattatt ctcctccaat cgtttttatt ttaattatat caaatttaga aaggaaaaat
     7501 atgagtaaag aactaaagat aatcaaggct aaaatcaaaa ctcgtttgat tgagctggat
     7561 atgactcaag ccgaattggc aaaacaagta tctgtaacat catcagttat ttcagaactg
     7621 ctgaagtatg gaaaaggaag tgattatgtg aaagaaaaag tcgtagatat tttgggtatt
     7681 gaaaaccctt gggaaaatag ttagagcatg aggaaatagt atgaacaacg cagcgcaaaa
     7741 agtaacacgg attgacaaag atgcctggga gattgctacg gagttggcga acgagtacgg
     7801 ggtatctatt tgtcacatca tcagtgagag cgtccgctac tgtgcagaga atgccgaatt
     7861 taaggagatg gacgttgtcg ttaaacgatt ggtagtcggc agtaaggtgc tggagtagga
     7921 gggtggagat gaatgaacta gtatggtttt actttgttgt cataatcaat cttatcattg
     7981 gttttgctac atactacgct agcaaaagag acagaaaaaa gcgcatcaac gagtataaaa
     8041 aaatacaaga tgatgagctt gaaagaatta gaaataaatt taatttatga ttttttagaa
     8101 gtcttttgaa taaatttttt atttagtttt tgtttgtgat tgttagcttt atcagctaat
     8161 tttaaagctt tgtccaaatc aacttcgcct gtaaaagttt tgtagataag atcattcatc
     8221 ttcatagcct tgtcggtttc agtatcaatc tgagatacct tttcaagttc ttgtaaccgt
     8281 aattcatgag cttgtttgac tttttcaagt tccaaggtgt gttgttgttt gagagtatct
     8341 atctgataat gaaattcttt ttcaagtttc tctacgatat gtgaatgttc tttggcctgt
     8401 ttttcaatct cagctttatt gttagctttt gatgcaatat atgaccataa acctgagatt
     8461 attgcaagaa tgacactaat tgcaggttga ataagaattt gataatccat aagatttctc
     8521 caatcgtttt attttcatta taccaaattt agaaaggaat actatgaacg aaatttttaa
     8581 ttttcacgga caagaagtcc gtactttgac aattgatgac gagccgtggt ttgtcgggaa
     8641 ggatgtagcg gacatcctag gatatagcaa ggctagaaat gcgattactc ttcacgttga
     8701 tgaagaggac gccctaaaac agggcatccc tactagtggc ggaacacagg atatgttgat
     8761 catcaacgaa tctggtctct actctctcat cttatccagc aagttgcctc aagctaagga
     8821 attcaagcgc tgggtgactt cagaggtctt gccagctatt cgcaagcagg gcggatttat
     8881 ccgcgaggac ttggacgagg atgcctttat cgctctattc actggtcaaa agaaattgcg
     8941 tgagcaacag gctaccatgc tggaagatat cgactatcta aagagtgagc aaccgattca
     9001 tccaagctat gctcagtcgt tactgaagaa gcgcaaagct cgggtcgtgg cttgccttgg
     9061 cggtattgac agtcctgctt atgcggataa ggtttttgct caatcagtct ttagacaagc
     9121 tgagattgat ttcaaagacc acttcaacat tagtcgctat gacttgctac ccaagaagca
     9181 tgcggatgcc gctcttgctt actggatgac gtgggagcca agcactaata ccaagatgaa
     9241 aatcatgaaa ttgaactcat ttgatgacgt ctagaaaggg gaagaagatg gacaatgttc
     9301 tactttcact gtctgaatgg attaaatcta ttatcaagga cacaatcaca aggctagtcg
     9361 aaatagaaaa agatagtgat cactatccag agttgatgga tgtgaacact acctgcgaat
     9421 ttctaggaat taagtatgcc accttttcag ataattatcg ttacttaaag ggatttccaa
     9481 aggaattacc tggtaagaaa tggtcaaaaa gagccatcaa agaatggctc tctaatcaaa
     9541 tataataact ttactaaaag gcttctggac aaggtcttag caaaattatt tgactatatt
     9601 atagcacaaa aagaggataa ggagataaaa atgtttgaac caccgatttt agaccagttg
     9661 atgggggttg gagccttact gcttggattt gcaggggctt gccgtcatat caaattgcag
     9721 gaacaacgca aggaagaaga aagacgagaa gagcaagaat ttgcgtctat gattattcaa
     9781 ggctataacc atgcttacga acgtggtaga gaagctgaac gtcaagaaat ccgcaagaat
     9841 attcgtcgtc cgttcaaggg ctttacctac gacaacgaac cgcctcaagg attgcgtcct
     9901 gagccattag ctttgccaga acctaaacag tctgcaatca gacttctgta atgaggaggg
     9961 caggaaatgg aagaattgat tgaatcgctg gataacctga ttatgattgt taaagaactg
    10021 gaaggaaggg aatcaacttc aagacatttt attacgatat gggaaaacga ttataaaaat
    10081 ctattactag tcaaagaata cctaaccgac tatgaaaaac tagcaaagga ctatcgttat
    10141 gtgaccctta aaaataagct gctaaagatt gaaaaaatgg agctggaagg caggcacatc
    10201 tatgaggata tgcggatgaa gtatcgtgcc aatcgcagga agtggggtgc tcggtatgtc
    10261 tgaaattaag tggataaaaa tcacaaccga tatttttgac gatgaaaaga tttgcctgat
    10321 tgatgccttg cctgatcctg atgccatctt agtgatatgg ttcaagattt tgacacttgc
    10381 tggaaaacat aacagtaatg gtttgttgat gatgactgat aaggttcact atacagatga
    10441 aatgttagct actatttttc gtagaccatt gaatacagta agaatggcta ttggagtttt
    10501 tgaacagttt gggatgattg agattatcga tggtattatt agcttgccaa attgggaaaa
    10561 acatcaaaac gttgacggaa tggagaaaat caaggaacag acacgtaacc gtgtagccaa
    10621 ataccgtaaa aaacagaaaa atcttgctct tggtaacgtt acaggtaacg ttacagtaac
    10681 ggacggtaac gcactagaag aagataaaga taagaataag aatagattag ataaagataa
    10741 gaataagaaa agaataacta ctactagtag tggtagtgaa gaaaatatct tagaactttt
    10801 tcaatctgag tttcgtagac tcttatctgg atttgaaatt gaagaaatca accatctact
    10861 aaatgagaat gatgtggatt tggtgaaaga agcattgaag actgctatta actcaggaaa
    10921 gccgaacatc aaatatattg gtgggatttt aagaaattgg cagatgaaca atgttaccac
    10981 tgttgaacag gttcgtcaat cggaaaagaa gaacaaggat aagaaagaag aacaggaggc
    11041 caaggacgaa tgggggtact agaactaatt gaacaattcg agattgacta ttatccgtta
    11101 agctacgaga agaaaactct tttagcagac caaccaattc atcaagtggt tgcctgcttg
    11161 tctgaaatgg ctagctggca tgaatgcgga ggtcggctag tatggtagac aatgtgtttg
    11221 aggaaatcgc cttatcttat cgtaggaata cagaacaaca agaagagttc tgcgaaaagc
    11281 ataacatccc tttgataaag atattgagga ccgagagtgt tgtatgtcgc atgtgtgaat
    11341 ctgagcggat tcatgaagaa aatcaggaaa gagtgaatga actggctaat gctgagaatg
    11401 agcgagagag gaaatactat cttgaaaagt tctctcttta tgatgaagtt ttgaaaaatg
    11461 ctactttgga caattttgaa acaccaaccg aaaaagaagc ggaaaagcta gcttttgcaa
    11521 agaggatttg tcgtgagtgg tctgagggtg ctaggaacaa catcgtgtta caaggagaag
    11581 ctggaacagg taagagccat ttggcttttg ctatggttaa ggctctatct gagtacacga
    11641 aagagattgc tatttttatt aacgtaactg acttgctgat gaagattaaa gctgatttta
    11701 gtcaggaaga gtttctggtc aataaaattg ctagtgctaa gttcttggtt ttggatgatt
    11761 taggaatgga aaaagatagc gaatggtcat ttactattct ctacaatatc ttgaataagc
    11821 gttcaaacac aatcattacc acaaatttga tttctgccga tattcaaaaa agatatggca
    11881 gacctttcat gtccagacta atgaagggtg tagataaaga ccatttgatg gttttcaatg
    11941 atttgacaaa caagcgaaag caatattttt agaatagggg tggctgatgt ttattttaaa
    12001 gcatgggaca agagaggata agccgtttct aaggtctgca attatcagtg tgactggctt
    12061 ggatatttcg tgttccgagg agaagaaagc catgcggttt atttctcggg cggctgccgt
    12121 acaggttgga aaggctttga ggggttcctt tgggaacttt taccctgttg aggtggagtg
    12181 atgatgaaat tcttaaatgg tgactgcatg gacatcatga aacaatatcc tgataattac
    12241 tttgacctag ctattgttga tccaccatat ttttctggtc cagaaaaaag gaaattttac
    12301 ggacggaaaa tcagtccaat aggtgtaagc agactctatg gcgaaatctc agagtggaaa
    12361 attccaaaca gagattattt tgatgaactt ttcagggtat ctaaaaatca aattatttgg
    12421 ggtgtgaact acttcgacta ttcttttggt tctggccgta ttgtgtggga caaagttaat
    12481 ggtcaatcaa gtttttcaga ttgtgagata gcgtactgca gttatcatga tagtactagg
    12541 ctatttcgtt acatgtggaa tggtatgatg caaggtaaat caatctctga aggtcatata
    12601 caacaaggaa ataaggcatt gaatgaggtt agaatccatc cgacacaaaa accagtcaac
    12661 ctttaccttt ggttattgca aacttacgca aaagaaggcg ataaaatact tgatactcac
    12721 gtcggttcag caagtagctt gattgcttgc ggagagctag gatttgacta tgttggatgc
    12781 gagattgata aaagtatttt caacctcgct caacagagac ttgatgctta tgagaagcag
    12841 ttgaagttat tttaggaggt attgatgtta gagctttact tcgtctataa cgggcactgc
    12901 aagttttacc ttgggaggtt tgacaatgtc gatgatctca ttgagcagat ggaagatcat
    12961 cagtgggctt tctcggctat cactcatcca agatttcaga agcacattgg tcagcggacg
    13021 acacgatttg actacggttc taaggattgt tactatttag cgactttttc aggagggaaa
    13081 taatggctaa aaatatttta atggatttag catttgagaa ttttcacaaa tgtatgggaa
    13141 tttctgattt agtgggaggt aagaaacatg gttggagtaa cctatcagga aattcatctc
    13201 tttgttgaat ttttgaaaga gcagtacggg caaggtcgtc cagactatat tgaagccctg
    13261 aacgacttag acggtctggt ggaagtctcc tacagagaag ctattgaaag gtttttagaa
    13321 gatgaagtac gataaacagg ctgagattga cggactgaaa cgcacgatcg atcaaaacga
    13381 agagaagata atcgagtatt cgaaaccgtg cgatgcacgc aagagacgta ttagagcgct
    13441 agagcgcgat ttgttgagga aaaagaataa agaattgaga cggaaagtgg aggagttgga
    13501 agatgatgga agagttaaag cgaaaagtta atgaagtata caactggacg gtagaagacg
    13561 ggaagccgca acctcccaag caagatttac cacaagcggt gaaagaccgg gcggactatt
    13621 tttgggaaat ggcagaagat ggtatgacgt ttatgggagc gatggaatgt atcttcgctg
    13681 atgaaaagcc tacagactat gatttgggag ctactaaggg ttggttgcca aaatctaagg
    13741 agtttgatga ttgggttggc tattcgccaa gcatggctca ggtagttatt gcagtttatt
    13801 tgatttatgg aggaaactaa gatgaatatt aaggcattga ttaagaagta tgaagaattg
    13861 tggaatgaac acagcccttt ttatgaacct gtaccttata cttcaatggt tgaacttttt
    13921 ttgaaagagt tgaaacaact agacgaaccc caaaaagtca aaattccgca gtttgtggcg
    13981 gattggattg aggtttgtaa agaacattta acaactagtc tatatactgc tatgactcca
    14041 aactttatga aagaaaacaa ccaaagtttc gatcttatat tatggattaa aaaggcgagc
    14101 aaccaagacc tcttcgctcg cgcatggctt gacggctatg aggtcgaaaa agagaagcgg
    14161 tatctggtaa agattaaagg gaatattaaa gaaaatatgt tggtttatgg agaacttttg
    14221 gaaaggtact tctttacaaa aagctttagt ttagacgatg ctatatattc ccacacccgt
    14281 aaagaactag aaaatgcaaa aatcggctgg gtgtttgatt gtgaagggtt tgagattgag
    14341 gaggtggagt gatgacacaa acacttgaag aaggaatgaa gaatcaaagt aaatgcataa
    14401 aagtcccaag ggaaatcaga ccgtttgata tagggtatcg aatagtgaac aaatacggtc
    14461 aagcgctcgc tttaagaaat ggggcaagta tattcgattt gccttttctg gctgaaaaag
    14521 ctatagaaaa agaatttggg aagaatgatc cagactttga catcggaaag cattctgttg
    14581 aagaggtcgc tattgtcaat ttaagtaaat ttcatagtta ttttgaagaa cgtgtatgag
    14641 aaagtgaaag ttggggatga ggtgatgttg tgaaattctt ggatttattc gcaggaattg
    14701 gcggttttcg tttaggaatg gagtctgccg gccataaatg tattggcttt tgtgaaattg
    14761 ataagtttgc tagagaaagc tataaagcga tacacaatac gaaaggagaa atagaattac
    14821 atgacatcac agcagtatca gatgaatcta ttcgaggaat cggaagtgtg gacattatct
    14881 gtggaggatt tccgtgccaa gctttctcaa ttgcaggaaa cagacgaggt tttgaagata
    14941 cacgaggaac tttgttcttt gaaattgcta ggttcgcatc tattctcaga cctaaatatc
    15001 tattccttga gaatgttaaa ggattgctca atcacgaaaa tggagttaca ttcgagacca
    15061 ttatctcaac cttggatgaa ctggggtaca acgtggaatg gcaagtgctt aacagcaaga
    15121 atttcggagt cccccaaaat cgggaacgag tgttcattat cggacatctt agaagagaac
    15181 ataccagaag aatttttcct ctcagcggaa aaaatcagtc aactagtaac caatcagtca
    15241 tgaaaattgg gaatataaac ccatctggca acggaatgaa tggggaagtc tatcaagctg
    15301 atggtctagc tcccacgcta acaacaaaca agggagaggg gcaaaagata gctataaaaa
    15361 gcaatactat aaaacaattt ggggtattgc aacccaattt taaccaatgt ggggtggttt
    15421 acgaaacaga cggcatcgca ccaactatca gagcctatca aggtggagga cttgagccta
    15481 aaattattca acgtgggcat ggttataata aaggcggaga acataacatc gctcctactt
    15541 taactagcaa tagctatcac gaaaacaatc atttatcaga tggatttagg attagaaagc
    15601 taacacctag agaatgctgg aggttacaag gttttcctga ttgggctttt gataaggcgc
    15661 aggaggtcaa ctctaacagt caattatata aacaagcagg aaatagcgtg acagttaatg
    15721 tcatagcagc aatagcaaag gagttatcat gaacacaata gagaaagtca aacaatggtt
    15781 tattgaccgt gatttagaaa acggtagggt cgttggattg atggtgcttt cgtcaaagag
    15841 gaggatttat aaaatgaaaa gactaggaat cattattggg gcggtatttg taatcgttgt
    15901 atcgccgttt gtagttcagt atggatggaa tgagattatc acaacaattg ttccagttgg
    15961 taaaattaca gtctggcaag cattagggat ggatgcacta ctatctttca tctggcctgt
    16021 gctatctagc aaaaaagaat ctgaagagga ttattcgtat gcggtaaaga gcagtatttc
    16081 aaaaatcatt acatgtgcat ttttgatatg gttagctagt ttgtttattt aaggagtgtt
    16141 agcatgatac caaaatttag agggttatcc attgacgaaa aaagcaaagg agaatggcaa
    16201 tacggacatt taattgaaga tagaggaaga gcatttatta tcaacgaagt ggtagaagcc
    16261 aatgaacaat acattactat aggttcttgg tgtcctgtaa atccagcaac attaggacaa
    16321 tcaacaggac tcagagacaa gaacggcaag gaggtattca tcggtgacat cgttaaatgt
    16381 acaagaggat gtctccatga agtatattta gaaaaagaat acggtggcac atacataggt
    16441 ggaatgcctg ctgtatacct aaaaggattt ggagatggat atgcgtggac ggaatatgag
    16501 gaaatcatcg gcaatgtcta cgaaaatccg gagcttttgg aggtcaacga gtgagatatt
    16561 ttaaaatact atgtttggta ttactgaaca aacagttaga ttttatggaa cgaagacaag
    16621 taggaataga tatccgatct cgacaatttt gataacttgt ttacattttt gaaaaacttg
    16681 gaggtggaaa ttgaaaaaat tgagcgacga agacctcaaa acattagaca gagaactttt
    16741 caaatttcaa aacattcaac gtacaataga tttgagaaga ctagaattag aaactcgaaa
    16801 cccagatgct cagagtggtc ccagcgtagg aataagcaaa cctaccgaaa ctatcgcagt
    16861 cagaatcgca gatgatccaa ccttaaaatt tctcgaaggg ttcaaagcta ttattaacaa
    16921 acttttgatc aatctagttg atgaagataa ggaaatcttt aatctgcgct ggagatatcc
    16981 tcaactgaga tgggaagaaa tagcagaaca gaaattcatg agcaaagcta caatctatcg
    17041 acgtagaaga attatcttag aacagtacgc tatactgaaa ggtgagttgt aaataagatt
    17101 gagacaaaag acatcttgaa gtctcacaaa aaaaggtcta ttatgatagc atgaacttct
    17161 gaaacaaaaa cacaaatcac atgttggagt catcctattt ttacagaaaa gttgtttaac
    17221 agaggaacat catgagtcag caaccagctg gctttttgtt ttgtagaaag gaggcagtta
    17281 tggaatttgt atcaccgata aaagacaatg atgatattca agctatgaaa gattatctca
    17341 gagaatggaa tgagatgtat tatatgctat tcatcacagg cctgaatact ggcttacgag
    17401 tcggagatat acttaccttg aaagttaaag atgttcaagg ttggcacatc aaactgagag
    17461 aacggaagac tggcaagcag ataacaagac ggatgacaaa agaactcaag aaagaaatga
    17521 ggagatatgt tgaaggcaaa ccatttcatc atttcttatt caagagtagg caaggtcaga
    17581 ataaagcgat cactcgtgag cgagcctatc aaatcataca tgaagcagct gaagaacttg
    17641 gcattgataa tgttggcaca catacaatgc gcaagacatt cggctataaa tattacaaca
    17701 agacaaagga cgtaggaaca ttacagaaaa tgttcaatca ctcatcacct gcaatcaccc
    17761 tgagatacat agggatagag caagcagagc ttgatgacgc actacggaac tttgtcattt
    17821 aattttttag atattacttt cacataatga gttaagcata aactaaaaaa atgaaactct
    17881 tcaaaaccca tgcttagtaa gggtttgaga ttcagagtga gtttaacaaa atataagata
    17941 tgtgaaagtg agggataaaa ttggtatagt tacaagaggt gaaaaatggt aaaagaatac
    18001 cgtatttgta aatggaatgc atataccgtt aacagccata ctagtaaaat ggaataattt
    18061 ttttaaagaa tcagaatgag acaaaagaca tcttgaagtc tcacaaaaaa aggtttatta
    18121 tggtagcata gatttcttgt atgaggaggg gataggtcaa aggcctgtcc cttttagcat
    18181 tgagaaagga ggtttgagat gtataacaaa cctatcagac catccttgaa atctaagaag
    18241 tgggagaagt tccgtgatag gataatgcgt aagcatgatt atctttgcca agaaagtttg
    18301 cgttacggaa tttctgttca agcagaaatg gtacatcata tctttcctgt gtctgaatat
    18361 cctgagcttg aatttgttga atggaattgc ttgccattga cgaataagaa acataatacg
    18421 tttcatgata gagtgaacga tagagtaatc aaccaaggat tgtattggca gaaaaaaaga
    18481 aaaaaagaat ttttaaattt tttcaaaaat gaaaaatgaa aatttttaat cccccctctt
    18541 tttgaaaaat cattttggcc agtagggtac cggtgaaggg aactttttcc aagtcggggg
    18601 ccttcaaaca aaaagggggt aaaaactaag cgattttgac gaaaggaggt agtttttggc
    18661 taaaccaatt acagcaaagt cgattaagtc aaaagtggtc aagcagatga aagacttggg
    18721 aacttatcgt aaagagttcg aaatgatcat tgacattttt gcaggtatgt tataccagta
    18781 tcagaaactt gctcaagatt atgttgatat gggttatcca gtaacagaca cctacgtcaa
    18841 taaggctggt gctgaaaatg agcgcaaagt tccaatcttg acagcgatgg aaattttgag
    18901 gaaagatata ctcagctact ctaatcagtt gatgatgaat cctaagtcgc tcggtgaggt
    18961 agtagaacaa gagggtgagt cagttcttac tgaggtactg aagttcaaga acgaaatcaa
    19021 gaagaagcga gtgactggca atgggtaatc ttgataaagc taaaaaatac gctcaacacg
    19081 tcttaactca ccgagaagaa cattgcgaag aaaacatcct tgctgctgaa cgttttttcc
    19141 gtgatttaga aaatccaacc tttgagatgg atgaggatat ggtggatttt gttattcact
    19201 ttatcgagaa cgtgatagtt catcagcagg gcgatgatat gtttgcggta tctatccgta
    19261 acaagccatt gcttttgcaa ccgtggcaac atttcgttgt agttaatctg tttggttttt
    19321 actacaaggg tacgaatgag cgcaggttca aagaagcgct catcatgctt gctcggaaga
    19381 atgggaagac ctcgtttact gctgcaatcg cacttgctta tcagatatta gatacagata
    19441 gcggttccaa atgctatatc gttgctaact cagtcaagca agcgatggaa gcttttggtt
    19501 ttttaagatt caacgttgaa cgctggaacg ataagaacat tcgtatcaag gataataacc
    19561 aagaacactc tatcaccgcc aattttggtg atgaaggttc tttctttatc caggctttag
    19621 cgaatgatga gagccgtctg gactctttga acggaaatgt tatcatcttg gacgaagctc
    19681 acacaatgag gaacagtaag aaacatggtc ttatgaaaaa aacaatgtca gcataccgta
    19741 acagtatgct ttttgttatc tctacagctg gggatattcc taccgggttc cttgctaacc
    19801 gtctgaaata ctgtcaaaag gtgctcaagc aattagtcac tgatgattca tttttcatct
    19861 tcatctgtaa ggctaatcaa tctgctgatg gggacgtggt gaactatctg gacgagaata
    19921 tcctcaagat ggctaatccg tcatggggtg tcacggtttc gctcaaggct ctcaaggaag
    19981 aagcagagca ggctatgaat gatcctcaga caagaaatga gtttttcaat aagaccttga
    20041 atatcttcac taactctatg aacgcttatt ttaatcctga tgagtttatt gcgtcggata
    20101 gttgctacga ttggagttta gaagagctgg cacgtttgcc tattcgttgg tatggtggtg
    20161 cggacttgtc aagattgcac gacttaacag ctgctgctct ctatggtgtc tatcatgacg
    20221 gtgagaaaga cgttgatatc tgtatcacac atgctttctt ccctcggatt aatgctcaga
    20281 aaaaagctaa tgatgacggg attccactct ttgggtggca gtctgacggt tggttgacga
    20341 tgagcaacac tccgaccgtc ctctatgatg atatcgtcaa atggttcatc aagatgaggg
    20401 agaaagggtt caagattgct gctgtcggaa tggataggaa gtttggccgt gagttcttga
    20461 cgaagatgaa acaagctcgg ttcaagatga ttgaccaacc tcagcttttt tatctgaaat
    20521 cagagggatt cagacggatt gagtttaaag ttaagaataa agaattttac tatcttcatt
    20581 ctgatgctta cgaatactgt gtgagcaatg ttagagcaat tgaaaaggtg gacgatgctg
    20641 tgcaatatga gaaattagat ggagacggtg ggactgcaag gattgacttg tttgatgcca
    20701 gcgtctttgc ttgtatacag gctcttgcta atcttggcaa gggtggtgat gtgatgagat
    20761 tctttgatta ggtgaattat gaatgaaata gtattatcag aacatgaaat taacttgctg
    20821 atcaacaaag ggcgagttaa agtaatttta aacggggaag tagtaactat tcgtcaaaga
    20881 catatgaaaa atttgatggc tgaaacagta aaatgggaaa aacaggtaat tgatgtcagt
    20941 cagaatatcg taagaaataa acactttgat tcactttttc aaaatacttt tcgttagaaa
    21001 ggaggtgagg aaacatgggt atttttgaaa agttttggaa acgaaacaag ccaagtaagt
    21061 caatcaacat gctgagtcat tcagatttag ggttgtcaaa cctgatggac tcgtatgtac
    21121 ctttggccag aaatccagat gtggtgacag cggttaataa gattgctgat ttggtctcta
    21181 atatgaccat ccacttgatg gagaatacag ataaaggtga tatcagaatc cgtgatgggc
    21241 ttgctagaaa gattgatatc aatccgtgta aacacatgac aaggaagtca tggattttca
    21301 agattgtgcg cgatttgctt ttatatggcg atgggaactc tgtcctacat gtggaatatg
    21361 aacctgttac ggattatatt tctaatctaa gaccatttcc gatgagagag gtttcattcc
    21421 aaacagataa ggattcctat gtaatctcat ttaggggtga agaatattcc cctgatgaag
    21481 tagtccactt cgtcatcaat ccagatccag atattctata cattggtact ggttttaggg
    21541 tgacgttgac agatgtggtt caaagtttga acatggctac caagactaaa aaaagcttta
    21601 tgaacgggaa gaatattcct agtcttatcg ttaaagtaga ctcgtctagt gctgaactag
    21661 attcggagca agggcgtgag cgtatcgctg agaagtattt gagtactagc agggttggcg
    21721 ctccatggat tgttccagag gcattgctgg acattcagca ggtaaaaccg cttagtctaa
    21781 cggacatcgc tttaaacgag tctgtggaat tggataaaag aacagttgca ggtctattag
    21841 gagtacctgc ttttattttg ggtgtaggag agttcaacaa gacagagtat aacaactttg
    21901 taaatacgac tgtcatgagt attgctacca ctattactca aacactaacc agggacttac
    21961 ttttgtctag caatcgttac ttcaagctaa atcctcgttc actcttctct tacaacatta
    22021 cggagttgtc tgctgttgct caacaaatgg caaacagtgc tgcaatgcgt cgtaatgagt
    22081 ggagggattg gctagggatg gctcctgatc ctgagatgga agagttgatt gttcttgaaa
    22141 actttctccc tcaggagaaa ctaggagatc aaaataaact gaagggaggt gaggaagaga
    22201 atgcaaaagc gaaatagcta tcgtgccact caatttcaaa cgagagaaga agaatctgga
    22261 gacttggtgt tgagtggcta ttttataaaa tttgatgaag agacggagtt gtggcgtggt
    22321 tatcatgaag taatcaagcg tgctggtgtt gagaaagctg tcacagacgc tgatatcaga
    22381 gctttattta accatgatga tagccttgtt ctcggtcgaa caggtaacgg aactctgaca
    22441 ctgggtgttg atgatgttgg tctttttgga gatatcatca ttaacaagga tgatcctcaa
    22501 gctgttgggg cctatgcccg tgtcaagcgt ggagatgtta tagggtgtag ctttggcttt
    22561 atcccggtaa aaatcgaaac ggaagaacgt gaagatggtt cgtatttgga cactgtctta
    22621 gagctagaaa tctttgaagt gagtccatgt actttcccag cctatccaca aacggaaatt
    22681 gctgcacgac aaaaagactt cgaaagtcag aagcgtgcta atcgtgaagc gctagacaag
    22741 cgcaagaaag aaattaagga gaaatttaag ctatgaataa ggcattaatc tttggtgctc
    22801 gtatgcgagc aaaagcaact aaggtagttg agttggaaga aactatcgaa gaattgaaca
    22861 aacgttcggt tgttgagtta gaaaagttgg atcgtgctaa aaatgatgaa gaagttttag
    22921 cagttgaaaa gactgtagac ggtcttcaaa gggaaattga agaaaaagaa gctgaaaaag
    22981 tacagcttga aaacgagatc gatgagttag ataaacaaat caaagagcaa aatcgtaaag
    23041 caccaactcc ggggaaaatg gaagaacgag gaggaaagac attgggacaa cgtgaagcat
    23101 ttaatcatta cttacgaaca aaagaagcgc gtgctgatgg tttcaaatct gccgaagggg
    23161 aagcaatcat tcctgttgaa ttgatgacgc ctaaagaagc gaaacaagac aagacagatc
    23221 tgacttcatt ggtcaacatc gttaatgtca agaacgcaag cggtaaatgg tcagttgtaa
    23281 aattgactga tcaagcaatg aacactgttg aagagttgga agaaaaccct gaattggcta
    23341 aaccaacctt tacaaaggtg aactatgaaa tcaaaacacg tcgtggtcat ttgccagtat
    23401 ctcaagaatt tattgatgac gctgactacg atgtcatggg attggttgct aaacaaacta
    23461 agaaccaaga acgtatcact aagaataaag agatcgctaa agttctcaag acagctacat
    23521 ctaaaagcgc agctggtttg gacggcttga aagatattct caacgtggaa ttgaaaacat
    23581 actacaatgc aactatcgta tgtactcaat ctatgttcgc tgctcttgat aaaatcaagg
    23641 acaaggacgg tcgctacatg ctccaaacag atatcacatc tccaactggc tacaagtttg
    23701 ctggtcgtgt tattgttgtt tatccagatg atatcattgg agaaagcaag ggagatttga
    23761 aagccttcat cggtgacgtt ggagaatttg cgacattgtt tgaccgtgcg cagactactg
    23821 tcaaatggca agatgacaaa atctacggtc agtacctagg aactgcaaac cgtttcgatg
    23881 ttaagaaagt tgatgaagca gcaggcttct atgtaactta cactgacgct gtagggtaag
    23941 gaggtagcgt atgagatata aagtaatccg tcctttcaag gacttggctg atcctgaaaa
    24001 tcatgactac gctgttggcg atatctttcc tcgtgaggga tatgagccaa cagatagctt
    24061 taccaatggc cttttgactg gcgctaacac tgctggctct atcttccttg aggttttggg
    24121 agatgatgaa cctaagaaac cagcgcctga aacaaaagaa gtgaaggaag agcccgcagt
    24181 tgagcaggaa gaaacagttg aggaaactgc tgaagagtct gctgaggaag ttgaggaata
    24241 gacatggacc aaggtcagct tttagagttg ctgaagctta agttgggtat ttcaaccgac
    24301 ttgagagaca agccgttaaa aaaaatcatt tcaagtgtca tcactgaatt gaccgataat
    24361 ctcggtatcg agcttgttgg tgagcgtgct gaccatgaaa tgtttatcgt tgactatgcc
    24421 gcttatcgtt atgagggtgg ggtggatatg ccacgtcacc ttcagtggcg actgcataat
    24481 ttacagatag catcaaagaa agaggtcaag aatgtggaat catgaaatca cactgatctc
    24541 caagaaagta acaggtaagg ataagttact acaaccaatc tctgaagatg ttgaagttac
    24601 tctcttatgt cgcaaaaaga gggtcactcg ctctgaattt tatcaggcga atcaggtagg
    24661 gcttaaaccg agcttggtcg ttgagattcg aaattttgag tatgagaatc aagagcttgc
    24721 gaagttcgaa ggcaagcaat atcatatctt gaaaacctat cctattgatt ctgaaatttt
    24781 agagttgact ttgtcagagg tgttgaaatg agtaatgacc ttgctgattt gatagcgaaa
    24841 gagcttgcag cttactctga tgaggttact gaagaagtgg ataagattgc agagcaagtg
    24901 gctgatgaga ctgtggatga gttgaaagag acaagtccga aacggtacgg aaagtatcgt
    24961 agaagttgga aaaagaagaa gttggccaat ggctcttttg ttgtgttcaa cgcagttgca
    25021 agtcttactc acatacttga aaacgggcac ctttcaagaa atggtggtcg tgtcgctggt
    25081 atcgtccaca tcaagccagc tgaagaaaaa gcaattcaga actttgagaa gcgaatcaag
    25141 gagattggga aatgaagcta tcagactttg ctgctatttt ggaacaggca aacttgcctg
    25201 tcacttatcg agcgtttaaa attggaaacg ctcctgacct accttacctg gtctattatg
    25261 aatcaagtcc agtcatcaat tcagctgaca acacggttaa tcatcagatt aagagcgtga
    25321 cagttgagct ggcttttgag agtaaggatg aagatttgga agaacgtctg gaagagctgt
    25381 gggcaaacca caagctcttt tttgaagttc aagaagaaac atttatcgag actgaaagac
    25441 tctatgtcaa gtcttacaca gtctatctat actaaggagg aatgacatga ctcaagaaaa
    25501 taaagtaacc tttggcctag aaaatgtaca tatcgcacct atcaagacac ttgcagcaga
    25561 tggagttatc acttacggcg atgtttttcg ttttcctgga gcaatagagc tgatacttga
    25621 tactaaaggg gaaacaaccc ctatcaaagc agacaacaag gattaccatt tcatgaattc
    25681 aaacgaagga tatgagggta aacttaaaat cccacacatc attgatgaat ttgcgacaaa
    25741 aattcttggt gaaatcaagg accctcaaac tggtgttatg actgaaaaag cagatgcgag
    25801 cttgacagag ttcgcaatga tgttccagtt tgaaggcgac aaaaacaaga ctcgctatgt
    25861 gatgtactac tgttttgcca gtcgcccatc tcttggctca aaaactaaga acgggacatc
    25921 aaccaacgaa cgtgaactta gtttcaaagc tagcccgcgt ccattggata cagttgtcaa
    25981 gcgttctatc acatcagctg atgacaagga tgcgtatgac aactggttca agaaagtcta
    26041 tgaacctact gcggttgtag cttaaggaga aaatctatgc gtaaaatcgt tttggttggt
    26101 gatcaggagt atgagttggg cactaatggc tatactccta tcgcctacaa gcaacaattt
    26161 gggaaagatt attttcaaga tttgttttca atgttgaaaa atcaatcatt catgaatgaa
    26221 ttgaacaagc tggaaactga caaagagttg actgcaactg atattgacat ttcgatgctg
    26281 tcagattttg atatgacatt tttcaaccgt cttttttgga cctttgctaa atctgcaaat
    26341 cctcacatca agccttatga acaattcttc atggaaatgg aagtctttcc gattcaggaa
    26401 gttgggcctg tattgatgga aatgctgaat gcgagcatga cgacaaaaaa gcaccagatg
    26461 aatcagaatc agctagcgaa gaaatcttca cagtagaatc ctacttatct tgctgtaaag
    26521 aaactggtct ttctattgat gatctaaagc acatttcaat cggaatggct ctggattatc
    26581 agacggatta tgtgaatcta cggagcgagg ataagggtgg cgaacggaaa gccacgcaag
    26641 ctgattttga cagtttttaa agaaaaatga gtgctgagag agcgattctg agaccaagtt
    26701 ccttggtctg gctgcattat cagtcgtaga agttctctca gcgcttttct attttttgag
    26761 aaaggaggaa atatggcagg aaatatcaaa ggtatcaaaa ttgaaatcga tggcgacacg
    26821 caacccttgc agaaggcgct gaaaaatgtc aataaggccg ctactgatgc aagtcaggag
    26881 ttgagacaga ttgacaaggc cttgaaattt gatacaggga acgtaacgct cctgactcag
    26941 aaacaagagg tcttacaaaa gcaagtttcg acgaccaagg agaaactgga aaccttgaga
    27001 caagctcagt ctcaggtgga acagcagttc aaaaatggtg atatcggtgc tgatcagtac
    27061 cgtgcctttc aacgcgaagt cgaagttact caaaacgtcc taaaaggata tgagggtaag
    27121 cttgcaaatg tgaaccaggc gcttgctgag aatgggaatg caactaaaag caaccaaacg
    27181 caactgaaag aattgcagaa tgaacagagt caacttgctt cagagatgac taaggtgaca
    27241 agctcattca aactgcaaga aagtgcttta ggttcaaatg ctagcgaagc tgagagaaat
    27301 gctcttgctc agaaaaagat tggtgcccag tctgagattg taagtaaaca gatttcaaat
    27361 ctagaacagc aattggaaat cactaaaaaa gaatttggtg agaactccac acaagccaac
    27421 aggatggaag ctgagctaaa tcaggctaag acagcattca atcatctcaa tgatgagatg
    27481 aaaggaacaa agtctgctgc tgatagcact caagaaagtt taagtgaaat atcaagaaat
    27541 ttaagagcag aactacttca acagtttagt gagaagttga gtgctatttc agaaaagctt
    27601 gtggaagtag gaaaagaagc gttagaagca gctgctcaaa tgcaagctag taatgctcaa
    27661 tttactaccg ttttcggaga tatggaaacc caagcaagag aagcgttgaa tgctattggt
    27721 caggaaatgg atattgtccc agagcgattg caaggatcat tcactcagat ggcttcattt
    27781 gcaaaaactt caggattgga tacagcagaa gctttggatc ttacttctcg tgcaactagg
    27841 gcagcagcag acggtgcagc cttctatgac aaatctattg agagcgtgac agagagctta
    27901 caatcttttt tgaagggaaa ctttgctaac gatgcggctc ttggcatttc tgcaacagaa
    27961 acgaccagga atgccgctgc aaataaattg tacggaaagt cattcaagga cttgagcgaa
    28021 gcgcagaagc aattgacctt gcttcagatg gtcgaagacg gaaataaact ctcaggagct
    28081 cttggacagg ctgcaagaga atcagacggc ctggaaaacg tgatggggaa tctgaaacaa
    28141 gctgggacca atgcattatc tgctattggt caacctcttc tagaaatgat gattcctgtt
    28201 tttcaaacct tggcaacgat tgtgaaaggt gtagctgagc tgttcagttc cttacctgct
    28261 ccagtaaaag attttgttgt tattttagga acagttgtga ctgctgtagg ggtcatagcc
    28321 cccatattct tatcgttgca agcccttgct gagtttttaa aaatatctat tggagaaatg
    28381 ataattgccg cattgccaat tattggaaca gctattgcaa ttgctgctgc agttgctgca
    28441 attattgtta ttgtaaaata tctctgggaa actaacgaag gttttcgaga tgcggtcacg
    28501 accgtttgga atgcgattct tgaagttatc aatgcagtcg tatcagagat ttctaatttt
    28561 gtcatgagta tctttggaac ggttgttgct tggtggacgg agaaccagga acttattcga
    28621 gcaagtgctg agactgtctg gaatgctatc tatacggtta taagcacaat tctggaaatt
    28681 ttaggtccac tcattcaagc tggttgggat aatatccaac ttgtcattac aacagcttgg
    28741 gaaatcatta agactgttgt tgagactgca ataaacgttg tccttggtat cattcaagca
    28801 gttatgcaga tcatcaatgg tgattggtca ggcgcttggg aaactattaa gggggtattc
    28861 tctactgtat ggcaagctat ccaaagcatt gttcagacta ttttctcagc tatccagagt
    28921 tatatttcaa atattctcaa cggcatttca ggaactgtat caaatatctg gaacagcatc
    28981 aaggacactg tctcaaatgt gttaaatgct atatctagta ctgtctcaag tgtttgggaa
    29041 ggtatcaaga gtaccatttc aagtgctatc aatggtgcaa gggatgctgt ttcttcagct
    29101 attgaagcca tcaaaggatt gtttaacttc aacatcagct ggccacatat cccactacct
    29161 cacttttacg tgagtggttc ggccaatcca ttagattggt tgagtcaagg tgttccaagt
    29221 attggaatcg aatggtatgc caaaggcggt atcatgacga aaccaactat ctttggaatg
    29281 aatggtaata acataatggt tggtggtgaa gctgggaatg aagcagtatt gccgcttaat
    29341 gacaaaacac ttggtgctat cggtcgaggt atagctcaga ctatgggtgg aacttcaccg
    29401 acaatcaaca ttactattac cggtaacacc gtcagagaag aagctgacat cattcggatt
    29461 gctgatgagg tagcgcagag gattgctgac gaattgcaac gtaagacaca attgagagga
    29521 gggtttacat gataaagcat aatgagcttg tgattgacgg tgtgagaaca tcgtcttttc
    29581 cgtttaaagt cattgtccat gattctcctt caattgctct gggagagagc aagacagctc
    29641 ttttggagca tggtggtatc agtggagcaa tcgttcagac gaacaaacat agggaattgg
    29701 tcaagaaaac ctatacgatt tacttggtca aacctactga agaacagatg aaccaattta
    29761 tgagtctgtt tatccgtgaa aagttctggc tagagagtga gcgagtcaaa acaactcgtc
    29821 tttggtgcta taaggtcaat gtgagcgacc ttgaagaagt gcaacctggt ctttacatga
    29881 ccaaagcaac cttcacttgt caccctacca aacacttcaa agtcactgat acacagagat
    29941 tgacaagaag tggaacttta accgttcaag gttctgctct tgcctttcct aaaatcacaa
    30001 ttgttggtca gagcgcttct gagacttcgt ttacaatcgc tggtcaggtc attcgtcttg
    30061 aaaagctctc agaatcgctt gtgatggtta ataatcctga caatcctagc tttaaaacga
    30121 caacagggaa gccagtcaaa tggtcagggg attttatcac agttgatcca gcgaaagtta
    30181 agaatattgg ggttgtttta ggcccaggta ttcaatcgat tgaaatcgaa acggtttggg
    30241 ggtgggcata attgctttat ctacttaata aagatgtaag aaccgttcga tggaacgggg
    30301 agccacttca tgaagcgact tcggcgattg ttaaagagat catgaatagt gatttcacct
    30361 taactgtgaa atatcccatt tccgactctg gtatttatca gctcatccaa gaagatatgt
    30421 tgataaaagc gccgactcct gttcttggtg cgcagctatt tcgcattaag aaacctgttg
    30481 aatacaatga tcatctggaa atcacagcct atcacatttc agacgatgtg atgcaacgtt
    30541 ctatcacacc agtaagtgtg actagtcaga gttgtggcat ggctctttct cgcatggtac
    30601 aaaacaccaa aacggctctt ggagacttct cattcaacag tgatatccag gaccatagga
    30661 ccttcaatac gactgaaaca gaaaccctat actctatatt gctggacggt aagcacagca
    30721 ttgttggtac atgggaaggc gagctggttc gtgataactt tgcgatgact gtcaagaaga
    30781 gtcgtgggga gaatcgtggt gttgttatta caacgcacaa aaatctgaag aactaccaac
    30841 gcacaaaaaa cagtcagaat gttgtcacaa gaattcacgc aaagtcgact tttaaacctg
    30901 aaggtgctga aaaagaaacg actatcagag tgactgttga tagtcctctt atcaactcat
    30961 acccttatat caatgaaaaa gagtatgaga acaacaatgc taaaactgtt gaagagttgc
    31021 agaagtgggc acagtctaag ttctcaaatg agggaattga caaggtctct gatgctatca
    31081 agattgaagc ttatgaactt gatgggcaag tggtccatat gggcgacacg gtcaatctca
    31141 agagctggaa acataatgtc gatgcattca agaaagctat tgcttatgag ttcgatgcct
    31201 taaaagaaga atacatctct ctgactttcg atgataaggc aggtattggt ggttctagag
    31261 cttctggtgg cctatctagc gcagccgatg caattcttgg agtgacagaa tctgcacaag
    31321 aaatcgccct tgacaaggct cttcaaaatg ctgacttaga ctttgatcat aaggctggat
    31381 tgcttagaca ggaaatttct gacgatattg aacttgccaa ggccaaggcg gaagaagtca
    31441 agcgagaact gtctgacact atcaatcagc gctttaatag ctttgacaac gggccattga
    31501 aagaaactaa gcgcaaggct gaggaagctt tgagacaagc tggcgcaagt agctctcttg
    31561 ctcaggaagc caagcggatt gggctggatt ctgttgctag acttgaagcg tttaagtcgc
    31621 agactacgag cgcacaaacg gctctgtcag gtgacttgga cgctctgaaa cggactatcg
    31681 tgaatgatat tcgaccgaag caagcacagg ctgaagctga gattgccaag caagctgaag
    31741 cacttagccg gactaaaaat gaactggctg gcgcaagtac cctgcttgca caggaagcta
    31801 agcggattga gctggattct gttgctagac ttgaagcgtt taagtcgcag actacgagcg
    31861 cacaaacggc tctgtcgggt gacttggacg ctctgaaacg gactatcgcg aatgatattc
    31921 gaccgaagca agcacaggct gaaactgaga ttgccaagca agttgaagca cttagccgga
    31981 ctaaaaatga actggctggc gtgaagtcag cgcaagcgac gtatgaggag acgacgactc
    32041 gtagactgtc agaactgacc aacttggcca atggtaaagc cagcaagtca gaactcacgc
    32101 aaacagctga ggagctggct agtcggattg cgagtgt
//
LOCUS       DBEJAU010000022        32004 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC323 isolate 683620
            SAMN38261939-rid24807223.denovo.022, whole genome shotgun sequence.
ACCESSION   DBEJAU010000022 DBEJAU010000000
VERSION     DBEJAU010000022.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261939
            Sequence Read Archive: SRR26833919
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 32004)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 32004)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576303.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576303.1
            Genome Coverage       :: 154x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/19/2025 01:05:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,121
            CDSs (total)                      :: 2,078
            Genes (coding)                    :: 1,943
            CDSs (with protein)               :: 1,943
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 36
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 72 of 135
            Pseudo Genes (incomplete)         :: 63 of 135
            Pseudo Genes (internal stop)      :: 51 of 135
            Pseudo Genes (multiple problems)  :: 46 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..32004
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261939-rid24807223.denovo.022"
                     /strain="GPSC323"
                     /isolate="683620"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            1..1679
                     /locus_tag="ACL29Z_001059"
                     /pseudo
     CDS             1..1679
                     /locus_tag="ACL29Z_001059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000031864.1"
                     /note="internal stop; incomplete; missing N-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology.
                     GO_function: GO:0000150 - DNA strand exchange activity
                     [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /pseudo
                     /codon_start=3
                     /transl_table=11
                     /product="recombinase family protein"
     gene            1947..2513
                     /locus_tag="ACL29Z_001060"
     CDS             1947..2513
                     /locus_tag="ACL29Z_001060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0069384.1"
                     /translation="MVILELYQNDYSKDLVAFDSIEDGKAFVAQIPGYTLETEDGVEV
                     EYFNPKNIPDYMEIIFNGNIVPLSRFMFDPGENVNIIWKEISNLSLKNDRVIEGYSKI
                     DAYVVNNHEVKAYVETRETNYRKAKDFLESRGYEIDRSFFGSEDGEAILYRKKGIEVW
                     HFLCHLDPMFVEIEDVEGYVKEEVGEIQ"
     gene            2835..3023
                     /locus_tag="ACL29Z_001061"
     CDS             2835..3023
                     /locus_tag="ACL29Z_001061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000179767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CopG family transcriptional regulator"
                     /protein_id="HGR0069385.1"
                     /translation="MATDKNRIMISLDDKNLEKLENLVEDARDRRGMRLTKSQVIELL
                     LNTVDYFDDIMGAIYSKK"
     gene            3085..3843
                     /locus_tag="ACL29Z_001062"
     CDS             3085..3843
                     /locus_tag="ACL29Z_001062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000262024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-grasp domain-containing protein"
                     /protein_id="HGR0069386.1"
                     /translation="MVVYIRQSKLPIEVSINKYNAQVGAYLQGEEAVLYQSFSEIKEL
                     TSEDIVVDYIMETRALLKMMGLNVPVHDYPIELKEFYGRKIYAGILGEIVNIPDNWGK
                     FIKPKAGSKVFTGRVVNGTHDLIGIGLPFDYPIWISEVVEFIAEWRCFVLDGRVLDVR
                     PYTGDYHAQFDASVIDEAISCWKDAPIAYGLDIGVTRDGRTLVVEVNDGYALGNYGLF
                     PLKSINFHRARWKEMVKPYFEKNEIFKIQQDVIF"
     gene            3901..4755
                     /locus_tag="ACL29Z_001063"
     CDS             3901..4755
                     /locus_tag="ACL29Z_001063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000900021.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ADP-ribosylglycohydrolase family protein"
                     /protein_id="HGR0069387.1"
                     /translation="MLGAIIGDIVGSVYEWNNIKTKDFPLFRKDCFFTDDTVMTCAVA
                     EAIMNGGQKDDFIDAMKKYGRMYPNADYGARFNAWLNSDNREPYNSFGNGSAMRISPC
                     AWIMDCGFYAKTGIWPSSRGLTSLSAEVTHNHPEGVKGAMATADAIFLCRFYFGGYCR
                     EYEQSINDNPTECKRRIKDYIEKEYDYNLSQTLDEIRPNYRFNETCQETVPQAIIAFL
                     ESRDFEDAIRNAISLGGDSDTLAAITCSIAEAAYGIPDWIKDKAYSYLDEPLKDVVRR
                     WENRIKAY"
     gene            4867..5748
                     /locus_tag="ACL29Z_001064"
     CDS             4867..5748
                     /locus_tag="ACL29Z_001064"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000710114.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0008654 - phospholipid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase family protein"
                     /protein_id="HGR0069388.1"
                     /translation="MKKAMVIINPTSGGEKALDYKEKLENKAKEYFEYVETKITEKAL
                     DATHFAEEASREQYDAVVVFGGDGTVNEVISGIDERDYIPKLGIIPGGTGNLITKLLE
                     INQDIDGAIDELDFDLTNKIDIGKANDNYFGYIFSIGSLPEAIHNVEIEDKTKFGILT
                     YAVNTMKSVMTDQVFNIKVETENGNYVGEASHVLVLLTNYFADKKIFEENKDGYANIL
                     ILKDASIFSKLSVIPDLLKGDVVANDNIEYIKARNIKISSDSELESDVDGDKSDNLPV
                     EIKVLAQRVEVFSKPKE"
     gene            5892..6518
                     /locus_tag="ACL29Z_001065"
     CDS             5892..6518
                     /locus_tag="ACL29Z_001065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001833748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0069389.1"
                     /translation="MKDKESYNKFIPKLYNEELLKNHFKETMCFSRKELNNKSIINQK
                     LIKFPIVGHEVWALFGKEKTGEWRCLQVGQSKNKVKAEIESLIEFMSYDYNQLVDSIK
                     DGVKNRNSTFYSNIYQSSKKSKNEFLYSHIASQYDEFQLCLLDIDKYLGFKNLKFENK
                     HISNIMKIAKPLYAEAKLAFETKSIYWTMYNSGVDGQAIMIFLGDNKD"
     gene            6814..8553
                     /locus_tag="ACL29Z_001066"
                     /pseudo
     CDS             6814..8553
                     /locus_tag="ACL29Z_001066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015511339.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0004553 - hydrolase activity, hydrolyzing
                     O-glycosyl compounds [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 13 protein"
     gene            8828..9283
                     /locus_tag="ACL29Z_001067"
     CDS             8828..9283
                     /locus_tag="ACL29Z_001067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000500472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0069390.1"
                     /translation="MGAARDFLELINHKGLPLFNPLVGDSHVNNRQEYDNTGSGNLQP
                     EKWNETAKQLYNIIMWLIILWNAKPDTPLFNFKDEVIKYKTYEPFESSIKRVNTTIKN
                     GSKGKTLTEMINGYRADNDIRDEICNFNILKNKIRDMKDQQGNTMESYF"
     gene            9824..10297
                     /gene="tnpA"
                     /locus_tag="ACL29Z_001068"
     CDS             9824..10297
                     /gene="tnpA"
                     /locus_tag="ACL29Z_001068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001206386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IS200/IS605-like element ISSpn6 family
                     transposase"
                     /protein_id="HGR0069391.1"
                     /translation="MREDNQSLSHTTWNCKYHIVFAPKYRRQIIYGRYKASIGRIIRD
                     LCERKGVIIHEANACSDHIHMLISIPPKLSVSSFMGYLKGKSSLMIFDKHANLKYKYG
                     NRKFWCRGYYVDTVGRNQKVIAEYIQNQLQEDRVADQLTLFESVDPFTGEINKRK"
     gene            10553..10774
                     /locus_tag="ACL29Z_001069"
     CDS             10553..10774
                     /locus_tag="ACL29Z_001069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000285460.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HGR0069392.1"
                     /translation="MYRRLRDLREDHDLTQKQIAKILSFTNSAYAKIERGEHTLTADV
                     LVTLSNFYDVSTDYLLELTDFPDKIRFRK"
     gene            11220..11522
                     /locus_tag="ACL29Z_001070"
                     /pseudo
     CDS             11220..11522
                     /locus_tag="ACL29Z_001070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0032196 - transposition [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase family protein"
     gene            11678..12907
                     /locus_tag="ACL29Z_001071"
     CDS             11678..12907
                     /locus_tag="ACL29Z_001071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012512582.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA];
                     GO_process: GO:0051301 - cell division [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FtsW/RodA/SpoVE family cell cycle protein"
                     /protein_id="HGR0069393.1"
                     /translation="MKISKRHLLNYSILIPYLLLSILGLIVVYSTTSAILIEEGKSAL
                     QLVRNQGIFWIVSLILIALIYKLRLDFLRNERLIILVILIEMLLLFLARFIGISVNGA
                     YGWISVAGVTIQPAEYLKIIIIWYLAHRFSKQQEEIATYDFQVLTQNQWLPRAFNDWR
                     FVLLVLIGSLGIFPDLGNATILVLVSLIMYTVSGIAYRWFSTILALVSAASVFVLTTI
                     SLIGVETFSKIPVFGYVAKRFSAFFNPFADRADAGHQLANSYFAMVNGGWFGLGLGNS
                     IEKRGYLPEAHTDFVFSIVIEEFGFVGASLILALLFFMILRIILVGIRAENPFNAMVA
                     LGVGGMMLVQVFVNIGGISGLIPSTGVTFPFLSQGGNSLLVLSVAVAFVLNIDASEKR
                     AKLYRELENQPMNRLLK"
     gene            12927..15623
                     /gene="ppc"
                     /locus_tag="ACL29Z_001072"
     CDS             12927..15623
                     /gene="ppc"
                     /locus_tag="ACL29Z_001072"
                     /EC_number="4.1.1.31"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000058210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008964 - phosphoenolpyruvate carboxylase
                     activity [Evidence IEA];
                     GO_process: GO:0006099 - tricarboxylic acid cycle
                     [Evidence IEA];
                     GO_process: GO:0015977 - carbon fixation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoenolpyruvate carboxylase"
                     /protein_id="HGR0069394.1"
                     /translation="MSLQKLENSSNKSVVQEEVLILTELLEDITKNMLAPETFEKIIQ
                     LKELSTQEDYQGLNRLVTSLSNDEMVYISRYFSILPLLINISEDVDLAYEINHQNNID
                     QDYLGKLSTTIKLVAEKENAVEILEHLNVVPVLTAHPTQVQRKSMLDLTNHIHSLLRK
                     YRDVKLGLINKDKWYNDLRRYIEIIMQTDMIREKKLKVTNEITNAMEYYNSSFLKAVP
                     HLTTEYKRLAQAHGLNLKQAKPITMGMWIGGDRDGNPFVTAKTLKQSALTQCEVIMNY
                     YDKKIYQLYREFSLSTSIVNVSKQVREMARQSKDNSIYREKELYRRALFDIQSKIQAT
                     KTYLIEDEEVGTRYETANDFYKDLIAIRDSLLENKGESLISGDFVELLQAVEIFGFYL
                     ASIDMRQDSSVYEACVAELLKSAGIHSRYSELSEEEKCDLLLKELEEDPRILSATHAE
                     KSELLAKELAIFKTARVLKDKLGDDVIRQTIISHATSLSDMLELAILLKEVGLVDTER
                     ARVQIVPLFETIEDLDHSEETMRKYLSLSLAKKWIDSRNNYQEIMLGYSDSNKDGGYL
                     SSCWTLYKAQQQLTAIGDEFGVKVTFFHGRGGTVGRGGGPTYEAITSQPLKSIKDRIR
                     LTEQGEVIGNKYGNKDAAYYNLEMLVSAAINRMITQKKSDTNTPNRYEAIMDQVVDRS
                     YDVYRDLVFGNEHFYDYFFESSPIKAISSFNIGSRPAARKTITEIGGLRAIPWVFSWS
                     QSRVMFPGWYGVGSSFKEFINKNPENIAILRDMYQNWPFFQSLLSNVDMVLSKSNMNI
                     AFEYAKLCEDEQVKAIYEIILNEWQVTKNVILAIEGHDELLADNPYLKASLDYRMPYF
                     NILNYIQLELIKRQRRGELSSDQERLIHITINGIATGLRNSG"
     misc_binding    15706..15923
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            16036..17040
                     /gene="trpX"
                     /locus_tag="ACL29Z_001073"
     CDS             16036..17040
                     /gene="trpX"
                     /locus_tag="ACL29Z_001073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan ABC transporter substrate-binding
                     protein"
                     /protein_id="HGR0069395.1"
                     /translation="MKNKRLIGIIAALAVLVAGSLIYSSMNKSEAQNNKDEKKITKIG
                     VLQFVSHPSLDLIYKGIQDGLAEEGYKDDQVKIDFMNSEGDQSKVATMSKQLVANGND
                     LVVGIATPAAQGLASATKDLPVIMAAITDPIGANLVKDLKKPGGNVTGVSDHNPAQQQ
                     IELIKALTPNVKTIGALYSSSEDNSKTQVEEFKAYAEKAGLTVETFAVPSTNEIASTV
                     TVMTSKVDAIWVPIDNTIASGFPTVVSSNQSSKKPIYPSATAMVEVGGLASVVIDQHD
                     LGVATGKMIVQVLKGAKPADTPVNVFSTGKSVINKKIAQELGITIPESVLKEAGQVIE
                     "
     gene            17109..17975
                     /locus_tag="ACL29Z_001074"
     CDS             17109..17975
                     /locus_tag="ACL29Z_001074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HGR0069396.1"
                     /translation="MIVSIISQGFVWAILGLGIFMTFRILNFPDMTTEGSFPLGGAVA
                     VTLITKGVNPFLATLVAVGAGCLAGMAAGLLYTKGKIPTLLSGILVMTSCHSIMLLIM
                     GRANLGLLGTKQIQDVLPFDSDLNQLLTGLIFVSIVIALMLFFLDTKLGQAYIATGDN
                     PDMARSFGIHTGRMELMGLVLSNGVIALAGALIAQQEGYADVSRGIGVIVVGLASLII
                     GEVIFKSLSLAERLVTIVVGSIAYQFLVWAVIALGFNTSYLRLYSALILAVCLMIPTF
                     KQTILKGAKLSK"
     gene            17972..18730
                     /locus_tag="ACL29Z_001075"
     CDS             17972..18730
                     /locus_tag="ACL29Z_001075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000125420.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGR0069397.1"
                     /translation="MTAIVELKNATKIVKNGFDEEKIILNDVSLEIFERDFITILGGN
                     GAGKSTLFNTIAGTLSLTSGTIRILGEELTKFSPEKRAKYLSRVFQDPKMGTAPRMTV
                     AENLLIAKFRGEKRGLLPRRLTSYKDEFQATIEKVGNGLEKHLNTPIEFLSGGQRQAL
                     SLLMATLKRPELLLLDEHTAALDPKTSVALMELTDEFVKKDQLTALMITHHMEDALKY
                     GNRLIVMKEGRIIQDLNQEEKAKMKISDYYQLFE"
     gene            18820..20580
                     /gene="dnaG"
                     /locus_tag="ACL29Z_001076"
     CDS             18820..20580
                     /gene="dnaG"
                     /locus_tag="ACL29Z_001076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000227865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003896 - DNA primase activity [Evidence
                     IEA];
                     GO_process: GO:0006269 - DNA replication, synthesis of
                     primer [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA primase"
                     /protein_id="HGR0069398.1"
                     /translation="MVDKQVIEEIKNNANIVEVIGDVISLQKAGRNYLGLCPFHGEKT
                     PSFNVVEDKQFYHCFGCGRSGDVFKFIEEYQGGTFMEAVQILGQRVGIEVEKPLYSEQ
                     KPASPHQALYDMHEDAAKFYHAILMTTTMGEEARNYLYQRGLTDEVLKHFWIGLAPPE
                     RNYLYQRLSDQYREEDLLDSGLFYLSDANQFVDTFHNRIMFPLTNDQGKVIAFSGRIW
                     QKTDSQTSKYKNSRSTAIFNKSYELYHMDRAKKSSGKTSEIYLMEGFMDVIAAYRAGI
                     ENAVASMGTALSREHVEHLKRLTKKLVLVYDGDKAGQAAILKALDEIGDMPVQIVSMP
                     DNLDPDEYLQKNGPEDLAYLLTKTRISPIEFYIHQYKPENSENLQAQIEFIEKIAPLI
                     VQEKSIAAQNSYIHILADSLASFDYAQIEQIVNESRQVQRQNRMEGISRPTPITMPIT
                     KQLSAIMRAEAHLLYRMMESPLVLNDYRLREDFAFATPEFQVLYDLLGQYGNLPPEVL
                     AEQTEEVERAWYQVLAQDLPAEISPQELSEVEMTRNKALLNQDNMRIKKKVQEASHVG
                     DTDTALEELERLISQKRRME"
     gene            20583..21692
                     /gene="rpoD"
                     /locus_tag="ACL29Z_001077"
     CDS             20583..21692
                     /gene="rpoD"
                     /locus_tag="ACL29Z_001077"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000201905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0016987 - sigma factor activity [Evidence
                     IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sigma factor RpoD"
                     /protein_id="HGR0069399.1"
                     /translation="MATKQKEVTTFDVQVAEFIRNHKQKGTATDDEINASLVIPFTLD
                     ADGIEDLLQRIQDAGISITDNEGNPSARVLSNEEEPELSDEDLIGSTSAKVNDPVRMY
                     LKEIGVVPLLTNEEEKELALAVEAGDIEAKQRLAEANLRLVVSIAKRYVGRGMQFLDL
                     IQEGNMGLMKAVDKFDYSKGFKFSTYATWWIRQAITRAIADQARTIRIPVHMVETINK
                     LVREQRNLLQELGQDPTPEQIAERMDMTPDKVREILKIAQEPVSLETPIGEEDDSHLG
                     DFIEDEVIENPVDYTTRIVLREQLDEILDTLTDREENVLRLRFGLDDGKMRTLEDVGK
                     VFNVTRERIRQIEAKALRKLRQPSRSKPLRDFIED"
     gene            21706..22035
                     /locus_tag="ACL29Z_001078"
     CDS             21706..22035
                     /locus_tag="ACL29Z_001078"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000331934.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-sulfur cluster assembly factor"
                     /protein_id="HGR0069400.1"
                     /translation="MAYTEEQIENIKTRILTALEEVIDPELGIDIVNLGLIYEIRFDG
                     DTGQTEIDMTLTTMGCPLADLLTDQIYDAMIEVPEVTDTEVKLVWYPAWTVEKMSRYA
                     RIALGIK"
     gene            22150..23193
                     /gene="cpoA"
                     /locus_tag="ACL29Z_001079"
     CDS             22150..23193
                     /gene="cpoA"
                     /locus_tag="ACL29Z_001079"
                     /EC_number="2.4.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-galactosylglucosyldiacylglycerol synthase"
                     /protein_id="HGR0069401.1"
                     /translation="MEKKKLRINMLSSSEKVAGQGVSGAYRELVRLLHRAAKDQLIVT
                     ENLPIEADVTHFHTIDFPYYLSTFQKKRSGRKIGYVHFLPATLEGSLKIPFFLKGIVK
                     RYVFSFYNRMEHLVVVNPMFIEDLVAAGIPREKVTYIPNFVNKEKWHPLPQEEVVRLR
                     TDLGLSDNQFIVVGAGQVQKRKGIDDFIRLAEELPQITFIWAGGFSFGGMTDGYEHYK
                     KIMENPPKNLIFPGIVSPERMRELYALADLFLLPSYNELFPMTILEAASCEAPIMLRD
                     LDLYKVILEGNYRATAGREEMKEAILEYQANPAVLKDLKEKAKNISREYSEEHLLQIW
                     LDFYEKQAALGRK"
     gene            23209..24534
                     /locus_tag="ACL29Z_001080"
     CDS             23209..24534
                     /locus_tag="ACL29Z_001080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399488.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HGR0069402.1"
                     /translation="MRIGLFTDTYFPQVSGVATSIRTLKTELEKQGHAVFIFTTTDKD
                     VNRYEDWQIIRIPSVPFFAFKDRRFAYRGFSKALEIAKQYQLDIIHTQTEFSLGLLGI
                     WIARELKIPVIHTYHTQYEDYVHYIAKGILIRPSMVKYLVRGFLHDVDGVICPSEIVR
                     DLLSDYKVKVEKRVIPTGIELAKFERPEIKQENLKELRSKLGIQDGEKTLLSLSRISY
                     EKNIQAVLAAFADVLKEEDKVKLVVAGDGPYLNDLKEQAQNLEIQDSVIFTGMIAPSE
                     TALYYKAADFFISASTSETQGLTYLESLASGTPVIAHGNPYLNNLISDKMFGALYYGE
                     HDLAGAILEALIATPDMNEHTLSEKLYEISAENFGKRVHEFYLDAIISNNFQKDLAKD
                     DTVSQRIFRTVLYLPQQVVAVPVKGSRRMLKASKTQLISMRDYWKDHEE"
     gene            24565..24741
                     /locus_tag="ACL29Z_001081"
     CDS             24565..24741
                     /locus_tag="ACL29Z_001081"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PspC domain-containing protein"
                     /protein_id="HGR0069403.1"
                     /translation="MRSGRDKKIAGVCAGVAHYLDMDPTIVQVIWGVLTCCYGAGIVA
                     YIILWIIAPVATDY"
     gene            24800..24934
                     /locus_tag="ACL29Z_001082"
     CDS             24800..24934
                     /locus_tag="ACL29Z_001082"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000863859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4044 domain-containing protein"
                     /protein_id="HGR0069404.1"
                     /translation="MAFGDNGNRKKTMFEKITLFIVIIMLVASLLGIFATAIGALSNL
                     "
     gene            24998..26308
                     /gene="obgE"
                     /locus_tag="ACL29Z_001083"
     CDS             24998..26308
                     /gene="obgE"
                     /locus_tag="ACL29Z_001083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase ObgE"
                     /protein_id="HGR0069405.1"
                     /translation="MSMFLDTAKIKVKAGNGGDGMVAFRREKYVPNGGPWGGDGGRGG
                     NVVFVVDEGLRTLMDFRYNRHFKADSGEKGMTKGMHGRGAEDLRVRVPQGTTVRDAET
                     GKVLTDLIEHGQEFIVAHGGRGGRGNIRFATPKNPAPEISENGEPGQERELQLELKIL
                     ADVGLVGFPSVGKSTLLSVITSAKPKIGAYHFTTIVPNLGMVRTQSGESFAVADLPGL
                     IEGASQGVGLGTQFLRHIERTRVILHIIDMSASEGRDPYEDYLAINKELESYNLRLME
                     RPQIIVANKMDMPESQENLEEFKKKLAENYDEFEELPAIFPISGLTKQGLATLLDATA
                     ELLDKTPEFLLYDESDMEEEAYYGFDEEEKAFEISRDDDATWVLSGEKLMKLFNMTNF
                     DRDESVMKFARQLRGMGVDEALRARGAKDGDLVRIGKFEFEFVD"
     gene            26318..26476
                     /locus_tag="ACL29Z_001084"
     CDS             26318..26476
                     /locus_tag="ACL29Z_001084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001841691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0069406.1"
                     /translation="MGDKPISFRDADGNFVSAADVWNEKKLEELFNRLNPNRALRLAR
                     TKKENPSQ"
     gene            complement(27351..27476)
                     /locus_tag="ACL29Z_001085"
     CDS             complement(27351..27476)
                     /locus_tag="ACL29Z_001085"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0069407.1"
                     /translation="MKIKDQTRKLAAGCSKHCFEVVDGTDVVSILHIRQGDIDVI"
     gene            27619..28878
                     /locus_tag="ACL29Z_001086"
     CDS             27619..28878
                     /locus_tag="ACL29Z_001086"
                     /EC_number="2.5.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001226236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008760 - UDP-N-acetylglucosamine
                     1-carboxyvinyltransferase activity [Evidence IEA];
                     GO_process: GO:0019277 - UDP-N-acetylgalactosamine
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine
                     1-carboxyvinyltransferase"
                     /protein_id="HGR0069408.1"
                     /translation="MRKIVINGGLPLQGEITISGAKNSVVALIPAIILADDVVTLDCV
                     PDISDVASLVEIMELMGATVKRYDDVLEIDPRGVQNIPMPYGKINSLRASYYFYGSLL
                     GRFGEATVGLPGGCDLGPRPIDLHLKAFEAMGATASYEGDNMKLSAKDTGLHGASIYM
                     DTVSVGATINTMIAAVKANGRTIIENAAREPEIIDVATLLNNMGAHIRGAGTNIIIID
                     GVERLHGTRHQVIPDRIEAGTYISLAAAVGKGIRINNVLYEHLEGFIAKLEEMGVRMT
                     VSEDSIFVEEQSNLKAINIKTAPYPGFATDLQQPLTPLLLRANGRGTIVDTIYEKRVN
                     HVFELAKMDADISTTNGHILYTGGRDLRGASVKATDLRAGAALVIAGLMAEGKTEITN
                     IEFILRGYSDIIEKLRNLGADIRLVED"
     gene            28894..29445
                     /locus_tag="ACL29Z_001087"
     CDS             28894..29445
                     /locus_tag="ACL29Z_001087"
                     /EC_number="2.3.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007521687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0016746 - acyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HGR0069409.1"
                     /translation="MNIWTKLAMFSFFETDRLYLRPFFFSDSQDFREIASNPENLQFI
                     FPTQASLEESQYALANYFMKSPLGVWAICDQKNQQMIGSIKFEKLDEIKKEAELGYFL
                     RKDAWSQGFMTEVVRKICQLSFEEFGLKQLFIITHLENKASQRVALKSGFSLFRQFKG
                     SDRYTRKMRDYLEFRYVKGEFNE"
     gene            29438..30715
                     /gene="spxR"
                     /locus_tag="ACL29Z_001088"
     CDS             29438..30715
                     /gene="spxR"
                     /locus_tag="ACL29Z_001088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016465747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS-HotDog domain-containing transcription
                     factor SpxR"
                     /protein_id="HGR0069410.1"
                     /translation="MSKHQEILSYLEELPVGKRVSVRSISNHLGVSDGTAYRAIKEAE
                     NRGIVETRPRSGTIRVKSQKVAIERLTFAEIAEVTSSEVLAGQEGLEREFSKFSIGAM
                     TEQNILSYLHDGGLLIVGDRTRIQLLALENENAVLVTGGFQVHDDVLKLANQKGIPVL
                     RSKHDTFTVATMINKALSNVQIKTDILTVEKLYRPSHEYGFLRETDTVKDYLDLVRKN
                     RSSRFPVINQHQVVVGVVTMRDAGDKSPSTTIDKVMSRSLFLVGLSTNIANVSQRMIA
                     EDFEMVPVVRSNQTLLGVVTRRDVMEKMSRSQVSALPTFSEQIGQKLSYHHDEVVITV
                     EPFMLEKNGVLANGVLAEILTHMTQDLVVNSGRNLIIEQMLIYFLQAVQIDDILRIQA
                     RIIHHTRRSAIIDYDIYHGHQIVSKANVTVKIN"
     gene            30731..31591
                     /locus_tag="ACL29Z_001089"
     CDS             30731..31591
                     /locus_tag="ACL29Z_001089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013903404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionyl aminopeptidase"
                     /protein_id="HGR0069411.1"
                     /translation="MITLKSAREIEAMDKAGDFLASIHIGLRDLIKPGVDMWEVEEYV
                     RRRCKEENFLPLQIGVDGAMMDYPYATCCSLNDEVAHAFPRHYILKDGDLLKVDMVLG
                     GPIAKSDLNVSKLNFNNVEQMKKYTQSYSGGLADSCWAYAVGTPSEEVKNLMDVTKEA
                     MYKGIEQAVVGNRIGDIGAAIQEYAESRGYGVVRDLVGHGVGPTMHEEPMVPNYGIAG
                     RGLRLREGMVLTIEPMINTGDWEIDTDMKTGWAHKTIDGGLSCQYEHQFVITKDGPVI
                     LTSQGEEGTY"
     gene            31816..31932
                     /locus_tag="ACL29Z_001090"
                     /pseudo
     CDS             31816..31932
                     /locus_tag="ACL29Z_001090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001136123.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="galactose-6-phosphate isomerase"
BASE COUNT        10283 a         5153 c         7002 g         9566 t
ORIGIN      
        1 tgtcaaaaga aaaaataaaa gtatacctct atacacgagt atctacgtca atacagatag
       61 aggggtattc gttagaggca caaaaatcac gaatgaaagc ttttgctatt tacaacgatt
      121 atgaaattgt tggagagtat gaagatgccg ggaagtctgg caagtctatt gaaggtagaa
      181 tacagttcaa tcgaatgatg gaagatataa aatctggaaa agatggagta tcttttgttc
      241 ttgtgtttaa gttatcaaga tttgcaagaa atgccgctga tgttctttct acacttcaga
      301 taatgcagga ttatggagtt aatcttatct gcgttgaaga tggcattgat tcatctaaag
      361 atgctgggaa actaatgatt tctgttttat cagctgtggc tgaaatagaa agagaaaaca
      421 tccgtattca aacaatggaa ggtcgcattc aaaaagcaag ggaaggaaaa tggaatggtg
      481 gctttgctcc gtatggatat aaacttgaag acggcaagct gtttataaat gaggaagagg
      541 cagttgcaat aagaacgatt ttcgaccagt atgtaaatac tacgatagga gccaatggga
      601 tatctaaata cttagagaat catggaatta gaaaaatccc aagacagaat ggtaagaatc
      661 ctttgtttga tgcaggtctt ataagaaaga tattaaagaa tcctgtatat aatgggaaaa
      721 tagcatttgg aagaagaact ttagaaaaag ttcatggtac aagaaatgaa tataagcagg
      781 ttgaacaaga tgaatatcta atatctgaag ggatacatga agctatagtt tccgatgaag
      841 tttggtaagc tgctcaggtt aagctaaaat ctcaagcaaa gaaatatgag catgtgaata
      901 aaggaaaaga tacacgcaca cacttgcttt ctggaattgt aaaatgcccg atatgtggag
      961 tgggaatgtt tgggaacaag tgtatcaaga aaaagaaaga tggcacaaag tataaagatt
     1021 tttattacta tggttgtaaa cataggcaga tgataagagg tcataagtgt acattcagta
     1081 agcaaattag agaagaattg ttagatgatg ctgttgcaga ggtgattgtc aagatagtaa
     1141 gtaatccgaa atttgcttct atgatgcaag aaaaaatcaa catgaaggtg gatacctctg
     1201 aaatagaaaa agaaatagat aattaccaaa aggaattgag aaagagtcat tctacaaagt
     1261 ttaagctaat tgaggaaata gataatttag atgttgaaga taagcattat aagagaagga
     1321 aacaggattt agatgataga ctatatcgta tgtatgacaa aatagatgaa ttagaatcat
     1381 cactaattga tgcgaaagca aagaaacaga ctattgaagc tgaaaagctt acaggagata
     1441 acatatataa ggttctgatc tattttgata agctctataa agtcatgaat gatgtagagc
     1501 gtaggcagtt aatttcagct ttgatttctg aaattcaagt ttatgaagaa aaacaatcta
     1561 acggacaatg gctaaaatcc attactttta agctaccaat tatagaagaa aatctcaaca
     1621 taggtttgga caatgatgaa caagttgaat gtgtaagttt attagagaaa cgtagttaat
     1681 cctcaaaagg ttccccgaac cttttgagtc ccactgacgc atcacgctga ggcggtatcg
     1741 ctgtttgtac gagttgaagc atcagcaaag taaaagtaga tgttcagcca atgcgacgag
     1801 gtgagaccga aggtcgataa ggtgtgttct gggtatagga ctcgtaaagt aagtaggaaa
     1861 tatgatgaga tgatacagag agcctgaatt ggtcaggtga cgtgcttatt tacattagcc
     1921 tgataatgaa aatggagaga ttatcgatgg ttatattgga attgtaccaa aatgattatt
     1981 ctaaagattt agtagcattt gattccatag aagatgggaa agcctttgta gctcaaatcc
     2041 cgggatacac tctggaaaca gaagatggtg ttgaagtgga gtattttaat cctaaaaaca
     2101 taccggatta tatggaaatt atttttaacg gaaatattgt tcctttatct agatttatgt
     2161 tcgatcctgg ggaaaatgta aacattattt ggaaagagat ttcaaattta tccctcaaaa
     2221 atgatagagt gatcgaagga tattcaaaaa ttgatgcata tgtcgttaac aaccatgaag
     2281 ttaaagccta tgtcgaaaca agagaaacga actatcgtaa agcaaaagac ttcttagaaa
     2341 gccgcggata tgaaatcgac agaagctttt tcggaagtga agacggtgaa gcgattcttt
     2401 acagaaaaaa agggatcgaa gtttggcatt tcttgtgtca cttagaccca atgtttgtag
     2461 agattgaaga tgtagaagga tatgttaaag aagaagttgg agagattcaa tagtcaacca
     2521 aagttccttg tgagtatata cctttgctag taaaagagtc aaaacgttat aacgaagggg
     2581 gggaagaaaa cccttgagtg taagtctttt tcttgtttag agggaaagta ttagagtagc
     2641 cgctcataat ttatactaga tttgataact gatttgagac agattttatt tctataaata
     2701 ttgtgaaaat tttttaatac caaagattta aagttactgt gttaaaaatc ctctccactt
     2761 ttaaactaat gtattataaa agccagttga cacaagtgtt acacctgtga tagaattaac
     2821 ttgaggtgat gaaaatggca accgataaaa atagaataat gattagcttg gatgataaaa
     2881 atctagagaa acttgaaaat ttagtagaag atgctagaga tagaagggga atgcgactaa
     2941 caaagtccca ggttattgaa ttactcctaa ataccgttga ttatttcgat gatattatgg
     3001 gggctattta ctcaaaaaaa taagagcaaa attgctatta ttttttacaa attggtgtaa
     3061 cactagtgat ataggagtga tgaaatggtt gtttatatta gacaaagtaa attaccaatt
     3121 gaggtttcaa ttaataaata caatgctcaa gtaggtgcct acttacaagg agaagaagct
     3181 gttttatatc aatctttttc tgaaataaaa gagttaacaa gtgaagatat agttgtagat
     3241 tatataatgg agactagagc attactaaaa atgatgggct taaacgttcc ggttcatgac
     3301 tatcctattg agcttaaaga gttttatggt cgaaagattt atgctggtat tttaggagag
     3361 attgtgaata tacctgataa ttggggaaaa tttattaagc ctaaagctgg ttcaaaagtc
     3421 tttactggaa gagttgttaa tggaacccat gatttaatag gtattggtct acctttcgac
     3481 tatcctatat ggattagtga ggttgtagaa ttcatagctg aatggcgttg ttttgtgtta
     3541 gatggtcgcg tattagatgt tcgaccctat acaggtgatt atcatgcaca atttgatgca
     3601 agtgtaattg atgaagcgat atcatgttgg aaagatgcgc caatagctta tggactagat
     3661 atcggtgtta ctcgcgatgg cagaacactt gttgttgaag taaatgatgg ttatgcattg
     3721 ggaaattatg gcctatttcc tttaaaatca atcaattttc atagagctag gtggaaagaa
     3781 atggtaaaac cctattttga aaaaaatgaa atttttaaaa tccaacagga tgttattttc
     3841 taaaataaat atggtagata accaatataa aaagcatcaa aatgaacaag gaggaatctg
     3901 atgcttggag caattattgg agatattgtc ggttctgttt acgaatggaa caatatcaaa
     3961 acaaaggact ttcctttatt tcggaaggac tgctttttta cagatgacac ggttatgacc
     4021 tgtgctgttg cagaagcaat tatgaatggt ggacaaaaag acgacttcat tgacgcgatg
     4081 aagaaatatg gcagaatgta tccgaatgct gattacggtg ctcggtttaa tgcatggcta
     4141 aacagcgata atcgtgagcc ttataatagc tttgggaatg gatcagctat gcgtatttct
     4201 ccatgtgctt ggatcatgga ctgtggtttt tatgcgaaaa ctggtatatg gccatcatct
     4261 agaggactta cgagtctttc tgcagaggta actcataatc atccagaagg tgtcaaaggc
     4321 gctatggcta cagctgatgc tatctttcta tgtcgttttt actttggtgg ttattgtaga
     4381 gagtacgagc aatcaattaa cgacaatcct acagagtgta aaagacgaat taaggattat
     4441 atagaaaaag aatacgatta caatctatct caaactttag atgaaatccg tcctaactat
     4501 cgttttaacg aaacatgtca ggaaactgtc cctcaagcca ttatcgcctt tcttgaaagt
     4561 agagacttcg aagatgcgat aagaaatgcc atctcacttg gtggcgacag tgatactctc
     4621 gcagcaatca cttgtagcat agcagaggca gcttacggta ttcctgattg gatcaaggat
     4681 aaggcctatt cttacttgga tgaaccctta aaggatgtag ttaggcgatg ggaaaataga
     4741 ataaaagcgt attaatctcc agtacgtcag atttctcttt tctgtatttt cattgtataa
     4801 taggattaca tttacttgca tacgacgaaa tgtaaacatt tctgtttaaa attaaggata
     4861 aaatcaatga aaaaagcaat ggtaattatc aaccctactt ctggtggcga gaaggctttg
     4921 gattacaaag aaaagctgga gaataaagca aaagaatact ttgaatatgt tgaaaccaaa
     4981 attaccgaaa aagcgctgga tgcaacacat tttgctgaag aagcttctcg tgagcagtat
     5041 gatgcagtgg ttgtgtttgg tggagatgga actgtcaatg aagtcatttc aggtattgat
     5101 gagagagact acattcctaa gttagggatt atcccaggcg gtacgggtaa cctcattaca
     5161 aaacttttgg aaatcaatca agacatcgat ggcgcaattg acgaactgga ttttgattta
     5221 accaataaga ttgatatcgg taaagcaaat gacaactatt ttggttatat ctttagtatc
     5281 ggttctctgc ctgaggcgat tcacaatgtt gaaatagagg acaaaacaaa attcggtatt
     5341 ttaacctatg ctgtaaatac catgaagtct gtcatgacag atcaggtctt taacattaag
     5401 gttgagacag aaaatggaaa ttatgttggt gaagctagcc atgttttggt ccttttgaca
     5461 aattacttcg ctgataagaa aatctttgaa gaaaacaagg acggctatgc caacattttg
     5521 attctgaaag atgcctctat attctccaaa ttatccgtca ttcctgattt attaaaaggg
     5581 gatgttgtcg caaatgataa tatcgagtat atcaaagcgc gtaatattaa aatctcttca
     5641 gatagtgaat tggagtcaga tgttgacgga gataaatcag ataacctacc tgtagaaatc
     5701 aaagtcctag ctcagcgagt agaagtattt tcaaaaccga aagagtaagt ttgtcattca
     5761 ctgagaaata aagttttata tcaacgaaag tagttacttg taagatttgc taaattttgt
     5821 aaaattaaca tgtcgtttaa aataattgga taatgggttt atataaaaat caggagaagt
     5881 tagaagaaaa aatgaaagac aaagaaagtt ataataaatt tattccaaag ttatacaatg
     5941 aagaactttt aaagaatcat tttaaagaaa ctatgtgttt ttctaggaag gaattaaata
     6001 ataagagtat aataaatcaa aagctcatta aattccccat agttggtcat gaagtttggg
     6061 cattatttgg taaagaaaaa acgggcgaat ggcggtgttt acaagttgga caaagtaaaa
     6121 ataaagtaaa ggccgaaatt gaatcattaa ttgaatttat gtcttatgat tataatcaat
     6181 tagttgatag tattaaagat ggtgtaaaaa atagaaatag tactttttat agtaatattt
     6241 atcaatcttc taaaaaaagc aagaatgaat ttttatacag tcatatagca agccaatacg
     6301 atgaatttca actttgtcta ctagatattg ataaatatct tggctttaaa aacttaaaat
     6361 ttgaaaataa acatattagt aatataatga aaattgcaaa accattgtat gcagaggcta
     6421 aacttgcatt tgaaacaaaa tctatatatt ggactatgta taattctgga gttgatggac
     6481 aagcaatcat gattttttta ggagataaca aagattaatt aaatgtcttc ttttctatct
     6541 tcaaatatat actactatct tgagtctata tgaaattgga attcaaaatt actaattaaa
     6601 tttgaataga ttgtaccata cttgtaaact ttatatcctt ctaatcaata gtagtaattc
     6661 aaagcctttt ttaaggcttt ttgtatactt taaaagatag ttcctttaac aacggacatt
     6721 ccttgcaaat agtttacaaa aatagtatac tggattcatt gagtttgaaa acgtttgcgt
     6781 aaaatttgaa tgaatacttt aggagacaaa ttgatggaat tgagtgctat ttaccatagg
     6841 cctgagtcgg agtatgccta tctttataag gataagaaac tccatattcg aattcgaact
     6901 aagaaagggg acattgaaag catcaacttg cactatgggg acccttttat ctttatggag
     6961 gagttttatc aggatacaaa agaaatggtc aagataactt ctggtacctt atttgaccat
     7021 tggcaggttg aagtgtcagt tgactttgca cgtatccagt atctctttga gctcagagat
     7081 acagaaggtc aaaatatttt gtatggcgat aaagggtgtg tggaaaattc tctagaaaat
     7141 cttcatgcaa ttgggaatgg atttaagttg ccttatcttc atgagattga tgcctgcaag
     7201 gttcctgact gggtttcaaa tacggtatgg tatcagatat ttcctgaaag atttgccaat
     7261 ggcaatgctc tattaaaccc agaagggact ttagactggg attcatctgt cacacctaag
     7321 agcgatgatt tctttggtgg tgatttacag gggattattg atcatatgga ttacttgcaa
     7381 gacttgggta ttactggact atatctttgt cccatctttg aatctacaag caatcacaag
     7441 tacaatacga cagattactt tgaaattgac cgtcattttg gagacaagga gacctttcgg
     7501 gaactggtgg atcaagcgca tcatcgtggc atgaaagtca tgctggatgc ggtatttaat
     7561 catattggtt cgcaatctct tcaatgaaaa aatgtcgtca aaaatggtga acagtctgct
     7621 tataaggatt ggttccatat tcaacaattc ccagtgacaa ctgaaaagct agttaataag
     7681 agagacttac cctatcatgt ttttggtttc gaggactata tgcctaagct aaatacagcc
     7741 aatccagagg tcaagaatta tcttttaaag gttgcgactt attggattga agagtttaat
     7801 atcgatgctt ggcgtttgga tgtggctaat gagattgacc atcagttctg gaaggatttt
     7861 cgtaaggcag ttttagctaa aaatcctgat ctttatatcc taggagaagt ctggcataca
     7921 tctcagcctt ggctaaatgg agatgagttc catgccgtca tgaattatcc tttatctgat
     7981 agtatcaagg actatttctt acgaggaatt aagaagacag accagttcat cgatgaaatc
     8041 aatggagagt ctatgtatta caagcagcag atttcagagg tcatgtttaa tctcttggat
     8101 tcacatgata cagagcgaat cctgtggacg gccaatgaag atgttcaact ggttaaatca
     8161 gccttagcct ttctcttttt acaaaaagga acaccgtgca tttattacgg aaccgagcta
     8221 gccttgactg gaggaccaga tccagattgt cgtcgttgta tgccttggga acgtgtatca
     8281 agtgacaatg atatgctgaa ctttatgaag aggctgatta aaattcggaa atacgcgtca
     8341 gtaatcattt cgcatggcaa gtatagcctt caagaaatca aatctgatct agtagctctg
     8401 gaatggaaat acgaaggacg gatcctcaaa gtaatattca accaatcaac agaagattat
     8461 cttttagaga aagaagcagt agcactagca agcaattgcc aagaattgga gaatcagctt
     8521 gtcatctctc cagatggatt tgtgattttc taaaaactag ttgatgaaga ttatggtaca
     8581 tttcatatct tatatagtat aataaggcta gttactaaac ttgtaaagga gaacttaaat
     8641 gaattgtaga ggacatgaaa caagacaaag aattgttaga gattttgaag tttagcctaa
     8701 agcacatatt aagctgttag caaatcaaca aaaacatagt gatgcaggag caactattga
     8761 agatgaatat tatgtattta tcgctgagag taaaattgat ggcaagaagg aagttattca
     8821 gtgttgcatg ggtgcggcaa gggatttttt agaactaatt aatcacaaag ggctacctct
     8881 ttttaatccg cttgtaggtg attctcatgt aaataataga caagaatatg acaatacagg
     8941 gagtggaaat ttacaacctg aaaagtggaa tgaaactgca aagcagcttt ataatattat
     9001 aatgtggttg attattttat ggaatgctaa gccggataca cctttattta attttaaaga
     9061 cgaagtaatt aagtataaaa catatgagcc ttttgaaagc agtataaaaa gagtaaatac
     9121 tactataaag aatggtagta aagggaaaac tctgactgag atgattaatg gctacagagc
     9181 ggataacgat attagagatg aaatttgtaa ctttaatatt ctgaaaaata aaattcgtga
     9241 tatgaaagac caacaaggaa atacaatgga atcttacttt tagttattgt tgaattttgg
     9301 gtattctata aaatatccta attgagattt aaatagtaga ctatacaata tagttaaaat
     9361 atcagtaaaa acaacacttt attgaggtat tggatacgct ttgctaatag cctaataatc
     9421 acatgtggag tgttgctaca acgaaaaagg tgataatcct tgatttcaag ctattttata
     9481 agcattttgt ctttgtagat aaaggcaatt ttgacaataa aaatcctaaa aggtgaatcg
     9541 ttatagatgt atttgtagat atcgtttgcg catcgaaaaa attaatacaa gaataaatat
     9601 ttatggctct ttaggtgact tttatagaag taaagtttag gatagaaaaa caagaaataa
     9661 cgcaccattt ttggtgcgtt atgctttttg ttgtctcccg aaaaccacta gctatgctag
     9721 tggttccata gagcttttag cgtggtaaca aaaagaacct cctaaaatga taagatagaa
     9781 gtggtttctc cgccactaca acatatcata caggaggtac ctcatgagag aggataatca
     9841 aagtttatca cataccacat ggaattgtaa atatcatatt gtttttgcac ccaaatatcg
     9901 tcgtcaaatc atttatggca gatacaaagc tagtatcgga agaatcatac gtgacttatg
     9961 tgagcgtaag ggtgtaataa tccatgaagc gaatgcttgt tcagaccata ttcacatgct
    10021 tatcagtatt cctccgaaac ttagtgtttc gtcctttatg ggctatttaa agggcaagag
    10081 cagtttgatg atttttgata agcatgcgaa tttaaaatac aaatatggca atcgcaagtt
    10141 ttggtgtaga ggctattatg tagatacggt aggccgtaat cagaaagtga tagctgaata
    10201 tattcagaat caattacaag aagacagagt agcagaccag ctcacgttat tcgagtcagt
    10261 agatccgttt actggcgaaa taaataagag gaagtaacta aggtgcttta gcacctgctc
    10321 gggaaagtgg tgcgcgagga agctatttcg gtgggccttt ggccctggcc ggtagaagcg
    10381 gcttatagcc gcagaacaaa ccaccagttc acactggtgg ttttgattta aaaaacttga
    10441 tacataaaaa taaaagtcta tataaaggat ggtaaaattc ctgttgtccg atttggacaa
    10501 tatcctaaat agttacaata tatggtctat acttttctca ggagaaagct agatgtacag
    10561 acgtttgaga gatttgaggg aagatcacga tttgacccaa aaacaaatag ctaaaatact
    10621 ttcgtttaca aactcagctt atgctaaaat tgaacggggt gagcatacgt taacagcaga
    10681 tgtattggta actctctcaa acttttacga tgtcagtaca gactacctat tggaattgac
    10741 agattttcct gataaaattc gctttagaaa ataatctcct caatttcata gagtgtgaaa
    10801 atgaggagat tttttatttg ttctttgaaa attaaatagt ccaaaatggt actttcctca
    10861 tttgtggagc aaatttgaat ggctcgccat gataagagcg attttaaaac catcaataaa
    10921 atagagcgat actttatatg ccatgataca aatgatatac aatgatactt ctgaccgttc
    10981 agcctgccaa cgtaaaagag cagcaagtga aattcttatg atgacttcat cagtcatgcc
    11041 acgttgaatg tgtgagtttg ttagataaac gcaattaatc ctcaaaaggt tccccgaacc
    11101 ttttgagttc tacagacgca tcacgtggag tgtgtaagct tgttgctaaa agcgtaaaaa
    11161 ccttggaacg aaaggaataa tagacttcct gcgaaacaaa aatataatac aataaaacta
    11221 tgaatgatga agcaagtaaa caattgagcg atagccgttt caagatcctt gtaggtgttc
    11281 agcgcacgac ttttgaagag atgttagctg tgttaaaaac agcttatcaa cgtaaacgcg
    11341 caaaaggtgg acgaaaaagc aaattaagcc tagacgatct ccttatggta actattcaat
    11401 acatgcgaga atagagcact tatgaacaaa ttgcggctga ttttggcatt cacgaaagca
    11461 acttaatccg tcggagtcaa tgggttgaag caactcttat tcaaaatggt tttacgattt
    11521 caaattctgc cttaattctg taaaaacagt aaaattcgaa ggattgtaag gtaagagttt
    11581 ttttctttct gaaaaaatgg tataatagca atcaaaacta gaaaataaaa cggaatttgg
    11641 aacagatttg tctgtatcct agtagagtgg tgatactatg aagattagta agaggcactt
    11701 attaaattat tccatcttga ttccctactt gcttttatct attttgggct tgattgtggt
    11761 ctattcgacc accagtgcta ttttaattga agaaggcaag agcgccttgc agttggttcg
    11821 aaaccaagga atcttttgga ttgttagttt gatactgatt gccttaattt ataaattgag
    11881 actagatttt ttgagaaatg agcgactaat cattttagtt atattaatag aaatgctttt
    11941 attgttcttg gctcgtttta ttggtatttc agtaaacggg gcatacggtt ggatttcggt
    12001 tgcaggagta actattcagc cagctgagta cttaaaaatc attattattt ggtatttagc
    12061 tcaccgattc tccaaacagc aagaagaaat agctacttat gattttcaag ttttgactca
    12121 aaatcaatgg cttccccgtg cttttaatga ttggcgattc gttctcctag ttctgattgg
    12181 aagtttggga attttccctg atttaggaaa tgcgactatt ttagtcttgg tttccttgat
    12241 tatgtataca gttagtggaa tcgcttatcg ctggttttca accattctgg cgctcgtatc
    12301 tgccgcttct gtctttgtct tgaccactat cagcctaatc ggtgttgaga ccttttcaaa
    12361 aattccagta tttggctatg tagccaaacg ctttagtgcc ttttttaatc cttttgccga
    12421 tcgtgctgat gcaggtcacc agttagctaa ttcttatttt gccatggtca atggtggttg
    12481 gtttggtcta ggtcttggaa actcgattga aaaacgaggt tatttgccag aagctcatac
    12541 agactttgtc ttttctatcg tgattgaaga atttggcttt gttggtgcca gtcttatttt
    12601 agctctcttg tttttcatga ttttgcggat tatcttggtc ggtattcgag cggagaatcc
    12661 tttcaatgcc atggttgcac tcggtgtcgg agggatgatg ttggttcagg tatttgtcaa
    12721 tatcggaggg atttcgggct tgattccatc tacaggagta accttcccct tcttatccca
    12781 gggtggaaat agtcttctag tcttatcagt ggcagtagcc tttgtcttaa atattgatgc
    12841 cagtgaaaaa cgcgctaagt tgtaccgaga attggaaaat caaccaatga accgtctgtt
    12901 gaagtaggat aaagaaagga tagtttatgt ctcttcaaaa attagaaaat tctagtaata
    12961 aaagtgttgt gcaagaagaa gtcttgattc taacagaatt actggaagat attactaaaa
    13021 atatgcttgc cccagagacc tttgaaaaaa taatacagtt gaaagaatta tcaacgcagg
    13081 aagattatca aggtctaaac cgtctagtga ctagcttatc aaatgatgaa atggtctata
    13141 tttcacgcta tttctctatc ttgcctcttt tgattaatat ttcagaggat gtggatttag
    13201 cttatgaaat caatcatcaa aataatattg atcaggacta tttaggtaaa ttatctacaa
    13261 cgattaaatt ggtagcagaa aaggaaaatg ccgttgagat cctagaacac ttgaatgttg
    13321 ttccggtttt gacagcccat ccaacacaag tgcaacgcaa aagtatgttg gatttaacaa
    13381 atcatattca tagtcttttg cgtaaatacc gtgatgttaa gttggggttg atcaataaag
    13441 ataaatggta caatgatttg cgtcgttaca tcgaaattat catgcagaca gacatgattc
    13501 gtgagaaaaa attaaaagtg actaacgaaa tcacgaatgc tatggaatat tataacagct
    13561 cctttttgaa agctgtacct catttgacga cggagtataa gcgcttagcg caagcgcatg
    13621 gtctgaattt aaaacaggct aaaccaatca ccatgggtat gtggataggt ggtgaccgtg
    13681 atggaaatcc atttgttaca gcaaagacct tgaagcagtc tgcactcact cagtgtgaag
    13741 tcatcatgaa ctactatgat aaaaagattt accaacttta tcgtgaattt tctctttcaa
    13801 ctagcattgt caacgtcagc aagcaagtca gagaaatggc tcgtcaatcc aaggataact
    13861 cgatttaccg cgaaaaagag ctttaccgtc gtgccttgtt tgatattcaa tcaaaaattc
    13921 aggcaactaa aacctatctg attgaggatg aagaagttgg gactcgttat gaaaccgcca
    13981 atgatttcta caaggatttg attgccattc gagattctct actagaaaat aagggcgagt
    14041 ccttgatttc aggtgatttt gtggaattat tgcaggcagt agagatattt ggtttttact
    14101 tagcatcaat tgatatgcga caagactcta gcgtctatga agcctgtgtg gcagaactct
    14161 tgaaatcagc aggaattcat tctcgttata gcgagttgag cgaagaagaa aagtgtgacc
    14221 ttctcttgaa agaattagaa gaagatcccc gaattctttc tgcgactcac gcagaaaaat
    14281 cagaattatt agcaaaagaa ctagctattt ttaagacggc tcgtgttttg aaagataagt
    14341 tgggagatga tgtcatccgt cagaccatca tttcacatgc aaccagcctt tctgatatgc
    14401 tagaattagc tattctgtta aaagaagtag gactggtgga tacggaaagg gcgcgtgttc
    14461 agattgttcc cctttttgaa acaattgaag acttggatca ttcagaggaa acaatgagaa
    14521 aatatctttc tcttagcctt gccaaaaaat ggattgactc acgaaataac taccaagaaa
    14581 tcatgcttgg ctactctgac agtaataaag atggcggtta cttgtcatca tgttggaccc
    14641 tctacaaggc tcaacagcaa ttgactgcta ttggagatga atttggcgtt aaggttacct
    14701 tcttccatgg tcgtggtggt actgtcggtc gtggtggtgg gccaacctat gaagccatta
    14761 catctcaacc gctcaagtct atcaaggatc gtatccgctt gacggagcag ggtgaagtaa
    14821 ttgggaataa atacggtaac aaagacgccg cttactataa ccttgaaatg ctagtatcgg
    14881 cagctattaa ccgtatgatt actcagaaga agagtgatac caatacccca aatcgttatg
    14941 aagccattat ggatcaagta gtggaccgta gttacgatgt ctaccgtgat ttggtctttg
    15001 gtaatgagca tttctatgat tatttcttcg agtcaagtcc aatcaaggct atttcaagtt
    15061 ttaatattgg ttctcgtcca gccgctcgta agactattac tgaaatcggt ggtttgcgtg
    15121 ccatcccttg ggtattctca tggtcacaga gtcgtgttat gttccctgga tggtacgggg
    15181 ttggttcaag cttcaaggaa tttatcaata aaaatccaga gaatattgct atcttacgag
    15241 atatgtacca aaattggcct ttcttccaat cgcttctttc aaatgttgat atggttttgt
    15301 caaaatcaaa tatgaatatt gcttttgaat atgctaaact ttgtgaagac gagcaagtta
    15361 aggccatcta tgagattatt ttaaatgaat ggcaagttac taagaacgtt atcttggcta
    15421 ttgaaggaca tgacgaactc ttagctgaca atccatatct aaaagctagt ctggattacc
    15481 gtatgcctta ctttaatatt ctcaactata ttcagttaga gttgattaaa cgccaacgtc
    15541 gtggagaatt gtccagtgat caagaacgat tgattcatat caccatcaac ggaattgcga
    15601 caggattgcg taattcaggt tgataatttt caagagtgaa tgctaaaagt gaatatcaaa
    15661 aaaattctaa tagactattg acaagtagtt taaaaatgat ataatttaac cattcagaaa
    15721 agtaatcata caaacttttt agagagtctg tggtagctga aaacagataa gtggcaatga
    15781 tgaaaattgg gctgaatgct atttagaatt tgaaattata aaaattcggt aagcacacct
    15841 tacagtgcat ctcgttattg cgagactgag cgatagggaa attccctata attgaggtgg
    15901 taccgcgcat cgacgtcctc acacaagttt tttgtgtgag gatttttttg atggaggtta
    15961 gtatggaaag aaaacgatgg cgtcgcttgt ttagataagt gaaatatgtt aaaggaaata
    16021 aaaaggagaa acagaatgaa aaataaacgt ttaattggaa ttattgctgc attagcagtc
    16081 ttagtagcag gaagcttgat ttattcttca atgaataaat cagaagctca gaataataag
    16141 gatgagaaga aaataaccaa gattggtgtg cttcaatttg tgagccatcc atcccttgat
    16201 ttgatttata aagggatcca agatggactt gcagaagaag gatataaaga tgatcaagtt
    16261 aaaattgatt ttatgaactc agaaggtgat caaagtaagg ttgcgacaat gagtaaacaa
    16321 ttggttgcaa atgggaatga ccttgtggtt ggtatcgcaa caccagcagc ccaagggttg
    16381 gctagtgcaa caaaagacct accagttatc atggccgcta ttacagaccc aattggtgct
    16441 aacttggtta aagatttgaa aaaaccaggt ggcaacgtta caggggtatc tgaccacaat
    16501 ccagctcaac aacaaattga actcatcaag gctctgacac cgaatgtgaa aacaatcgga
    16561 gctctttact caagtagcga agacaattca aaaacacagg tcgaagaatt taaggcttat
    16621 gctgaaaaag caggtctgac agtggaaaca tttgcagttc cttcaacaaa tgaaattgcc
    16681 tcaactgtca ctgttatgac tagcaaggta gatgctattt gggttccaat tgataacacc
    16741 attgcatcag gatttccaac ggttgtctct agcaatcaaa gttctaagaa accaatttat
    16801 cccagtgcga cagctatggt agaagtaggt ggtttggcat cagttgtaat tgaccaacat
    16861 gaccttggtg tggcaacagg taaaatgatt gtgcaagtct tgaaaggtgc aaaaccagcc
    16921 gataccccag tcaatgtctt ttcaactggt aagtcagtca tcaataaaaa aatagcacaa
    16981 gaactaggta ttactattcc tgagtctgtt ctcaaagaag caggacaagt catcgaataa
    17041 ataaggtagg gaggaggaga ctcttcccat tttttaaaaa gatgaatata gaaaggatta
    17101 aataaaatat gattgtttcc attatttctc aaggatttgt ctgggctatt ctaggtctgg
    17161 gaatctttat gacatttagg attttaaact ttccagatat gacgacagaa ggttccttcc
    17221 ctcttggggg agctgttgct gtcactttga taaccaaagg cgtgaaccca tttttagcga
    17281 cacttgttgc tgtaggagca ggttgtttgg ctggaatggc agcaggcctt ctttatacaa
    17341 aagggaagat cccaaccttg ctctcaggga ttttggtgat gacttcttgt cactcaatca
    17401 tgctcttgat tatgggacgt gcgaatttag gcctgcttgg aaccaagcaa attcaggatg
    17461 ttttgccttt tgattcggat ttgaatcaac tcttgacagg tctcatcttt gtgagtattg
    17521 ttattgctct catgctcttt ttcttggaca ctaaactcgg acaagcctat attgctacag
    17581 gggataatcc tgatatggct agaagtttcg ggattcatac tggacgcatg gagctcatgg
    17641 gcttggtctt atcaaatggt gtgattgccc ttgcaggtgc cctcattgct cagcaagaag
    17701 gctatgccga tgtgtctcga gggatcgggg ttatcgttgt ggggcttgca agtttgatta
    17761 ttggagaagt tattttcaag agtttgagct tggcagagcg tttggttact atcgttgtag
    17821 gttctatcgc ttatcaattt ttagtgtggg cagttatcgc acttggcttt aatacaagtt
    17881 accttcgttt atacagtgcc ttgattttag cagtctgcct catgattcca acatttaagc
    17941 aaacaatctt gaaaggagcc aagttaagca aatgacagca attgtagaat taaaaaatgc
    18001 aaccaaaatc gttaaaaatg gctttgatga agaaaagatt attttaaatg atgtttcctt
    18061 agaaattttt gaacgggact ttatcacgat tttgggcgga aatggtgctg gaaaatcaac
    18121 cctctttaac actatagcag ggaccttatc actaactagt ggaactatcc gtattttagg
    18181 tgaagaactc actaagtttt cacccgagaa gcgtgccaag tacctgtctc gtgtcttcca
    18241 agatccaaag atggggacag ctccccgtat gacggtcgct gaaaatcttt taatcgccaa
    18301 gtttcgtggt gaaaagcgtg gattgttacc acgacgcttg actagctata aggatgaatt
    18361 tcaggcaacc attgaaaaag taggaaatgg tcttgagaaa cacttgaata caccgattga
    18421 gttcttatca ggtggacaaa gacaggcttt gagtctcttg atggcaacct tgaagcgacc
    18481 tgaattactc ctgttagatg agcatactgc tgccctggat ccaaagacta gtgttgcttt
    18541 gatggaattg acagatgaat ttgttaagaa agatcagcta acagccctta tgattactca
    18601 tcatatggaa gatgctctca aatacggcaa tcgcttgatt gtcatgaaag aaggacggat
    18661 tatccaagat ttaaaccaag aagaaaaagc aaaaatgaaa atctctgatt attatcaact
    18721 ctttgaataa agtagggaaa atgagtgaaa tggtttactt tttttctgaa ataaagtata
    18781 ctatataaag taaactatga taacatggag gtattgtgta tggttgacaa acaagtcatt
    18841 gaagaaatca aaaacaatgc caacattgtg gaagtcatag gagatgtgat ttctttacaa
    18901 aaggcaggac ggaactatct agggctctgt ccttttcatg gtgaaaaaac accttctttc
    18961 aacgttgtag aggacaagca gttttaccac tgttttggtt gtggtcgctc aggtgatgtc
    19021 tttaaattca tcgaggagta ccaagggggt acctttatgg aggctgtcca aatcttaggt
    19081 cagcgtgtcg ggattgaggt tgaaaaaccg ctttatagtg aacagaagcc agcctcgcct
    19141 caccaagctc tttatgatat gcacgaagat gcggctaaat tttaccatgc tattctcatg
    19201 acaacgacta tgggcgaaga ggccagaaat tacctttatc agcggggttt gacagatgaa
    19261 gtgcttaaac atttttggat tggtttagca cctccagaac gaaactatct ctatcaacgt
    19321 ttgtctgatc agtatcgtga agaagattta ctggattcag gcctgtttta tctctcggat
    19381 gccaatcaat ttgtagacac ctttcacaat cgcattatgt ttcccctgac aaatgaccaa
    19441 ggaaaggtca ttgccttctc aggtcgtatc tggcaaaaaa cagattcaca aacttctaag
    19501 tataaaaaca gccgatcgac tgcaattttt aacaaaagtt acgaattata tcatatggat
    19561 agggcaaaaa aatcttctgg aaaaactagt gagatttacc tgatggaagg attcatggat
    19621 gttattgcag cctatcgggc tggaatcgaa aatgctgtgg cgtcgatggg aacggccttg
    19681 agtcgagagc atgttgagca tctgaaaagg ttaaccaaga aattggttct tgtttacgat
    19741 ggagataagg ctgggcaagc cgcgatattg aaagcattgg atgaaattgg tgatatgcct
    19801 gtgcaaatcg ttagcatgcc tgataacttg gatcctgatg agtatctaca aaaaaatggt
    19861 ccagaagact tggcctatct attaacgaaa actcgtatta gtccgattga gttctacatt
    19921 catcagtaca aacctgaaaa cagtgaaaat ctgcaggctc agattgagtt tattgaaaaa
    19981 atagctccct tgattgttca agaaaagtcc atcgctgctc aaaacagtta tattcatatt
    20041 ttagctgaca gtctggcgtc ctttgattat gcccagattg agcagattgt taatgagagt
    20101 cgtcaggtgc aaaggcagaa tcgcatggaa ggaatttcca gaccgacgcc aatcaccatg
    20161 cctatcacca agcagttatc ggctattatg agggcagaag cccatctact ctatcggatg
    20221 atggaatccc ctcttgtttt gaacgattac cgtttgcgag aagactttgc atttgctaca
    20281 cctgaatttc aggtcttata tgacttgctt ggccagtatg gaaatcttcc tccagaagtt
    20341 ttagcagagc agacagagga agttgaaaga gcttggtacc aagttttagc tcaggatttg
    20401 cctgctgaga tatcgccgca ggaacttagt gaagtagaga tgactcgaaa caaggctctc
    20461 ttgaatcagg acaatatgag aatcaaaaag aaggtgcagg aagctagcca tgtaggagat
    20521 acagatacag ccctagaaga attggaacgt ttaatttccc aaaagagaag aatggagtaa
    20581 taatggcaac aaaacaaaaa gaagtaacaa catttgacgt acaggtagca gaatttatcc
    20641 gtaatcataa gcaaaaaggg acagcaacag atgatgaaat caatgcaagt ctggttattc
    20701 cttttacctt ggacgctgat gggattgaag atctcttgca acggattcag gatgcaggca
    20761 tttctatcac agataacgaa ggaaatccaa gtgcgcgtgt tcttagcaat gaagaagaac
    20821 cagaactcag cgatgaggac ttgattgggt caacttctgc taaggtcaat gaccctgtcc
    20881 gtatgtactt gaaagaaata ggggtcgttc ctctcttgac caatgaagag gagaaagagt
    20941 tggcactggc tgttgaagct ggcgatatcg aagccaaaca acgtcttgcg gaagccaatc
    21001 ttcgtttggt tgtttccatt gccaaacgct atgtcggtcg tggcatgcag ttccttgact
    21061 tgattcaaga aggaaatatg ggcttgatga aggcggttga caagtttgac tattctaaag
    21121 ggttcaagtt ttcaacttat gcaacttggt ggattcgtca ggctatcact cgtgctattg
    21181 cggatcaagc tcgtaccatc cgtatcccag ttcacatggt tgaaactatc aataaattgg
    21241 ttcgtgaaca gcggaatctc cttcaagaat tggggcaaga tccgacacca gaacagattg
    21301 ctgaacgaat ggatatgaca cctgataagg ttcgtgaaat cttgaagatt gcccaagaac
    21361 cagtatctct tgaaactcct atcggtgaag aggacgatag ccaccttgga gactttatcg
    21421 aagatgaagt gattgaaaat ccagtggatt atacgactcg tatcgtcttg cgtgagcaat
    21481 tggatgaaat cttagatact cttacagacc gtgaagaaaa tgttctgcgt ctacgttttg
    21541 gactagatga tggaaaaatg cgcacacttg aagatgtggg gaaagtcttt aacgtaactc
    21601 gtgagcgtat ccgtcagatt gaagcaaagg ctttgagaaa actacgccaa ccaagccgca
    21661 gcaaaccgct tcgtgatttt attgaagact aagagtgagg aaaatatggc ttatacagaa
    21721 gagcaaattg aaaacatcaa aacacggatt ttaacagcct tggaagaagt catcgaccct
    21781 gagttgggaa tcgatattgt caatcttggt ttgatctatg agattcgttt tgacggtgac
    21841 acagggcaaa cagagattga catgactttg acaactatgg gttgtccctt agcagacctt
    21901 ttgacagacc agatttatga tgctatgata gaggttccag aagtaacgga tactgaggtt
    21961 aaattagtct ggtatccagc ctggacagtt gaaaaaatga gtcgctatgc ccgcattgcc
    22021 ctaggcatta agtaaacata taaaagtatg tgagagactg ttggaaaagc gaggaaattt
    22081 cccctctttt cctctagtct ctcctttctt ttgctgattt tattcaaaga aaatgatata
    22141 atagtagtta tggagaaaaa gaaattacgc atcaatatgt tgagttcaag tgagaaagta
    22201 gcaggacagg gagtttcagg tgcttaccgt gaattagttc gtcttcttca ccgtgctgcc
    22261 aaggaccaat tgattgttac agaaaatctt ccaatcgagg cagatgtgac tcactttcat
    22321 acgattgatt ttccctatta tttatcaacc ttccaaaaga aacgctcagg gagaaagatt
    22381 ggctatgtgc atttcttgcc agctacactt gaaggaagtt tgaaaattcc atttttctta
    22441 aagggaattg tgaaacgcta tgtattttct ttttacaacc ggatggagca cttggttgtg
    22501 gtcaatccta tgtttattga ggatttggta gcagctggta ttccacgtga aaaagtgacc
    22561 tatattccta actttgtcaa caaggaaaaa tggcatcctc taccacaaga agaggtagtc
    22621 agactgcgca cagatcttgg tcttagtgac aatcagttta tcgtagtagg tgctgggcaa
    22681 gttcagaaac gtaaagggat tgatgacttt atccgtctgg ctgaggaatt gcctcagatt
    22741 acctttatct gggctggtgg cttctctttt ggtggtatga cagatggtta tgaacactat
    22801 aagaaaatta tggaaaatcc ccctaaaaat ttgatttttc caggcattgt atcgccagag
    22861 cggatgcgcg aattgtatgc tctagcggat cttttcttgt tgcctagtta caatgagctc
    22921 tttcctatga ctattttaga agctgcgagt tgtgaggctc ctattatgtt gcgtgattta
    22981 gatctctata aggtgatttt ggagggaaat tatcgggcga cagcgggtag agaagagatg
    23041 aaagaggcta ttttggaata tcaagcaaat cctgctgtct taaaagatct caaagaaaag
    23101 gctaagaata tttccagaga gtattctgaa gagcatctgt tacaaatctg gttggacttt
    23161 tatgagaaac aagccgcttt agggagaaag taaaaagtga ggtaatctat gcgaattggt
    23221 ttatttacag atacctattt tcctcaggtt tctggtgttg cgaccagtat tcgaaccttg
    23281 aaaacagaac ttgaaaagca gggacatgct gtttttatct ttacgacgac agataaggat
    23341 gtcaatcgct acgaagattg gcaaattatc cgcattccaa gtgttccttt ctttgctttt
    23401 aaggatcgtc gctttgccta ccgaggtttt agcaaggcac ttgaaattgc taaacagtat
    23461 cagctagata ttatccatac tcagacagaa ttttctcttg gcctgttggg gatttggatt
    23521 gcgcgtgaat tgaaaattcc agtcatccat acctatcaca cccagtatga agactatgtc
    23581 cattatattg ctaaggggat attgatccgg ccgagtatgg tcaagtatct ggttagaggt
    23641 ttcctgcatg atgtggatgg ggttatttgc cctagtgaga ttgtccgtga cttgctatct
    23701 gattataagg tcaaggttga aaaacgggtc attcctactg ggattgaatt agccaagttt
    23761 gagcgtccgg aaatcaagca ggaaaatttg aaagaactgc gtagtaaact agggattcaa
    23821 gatggtgaaa agacgttgct tagtctttcg agaatctcct atgaaaaaaa tattcaagca
    23881 gttttagcag cctttgctga tgttctgaaa gaggaagaca aggttaaact ggtagtagct
    23941 ggggatggcc cttatctgaa tgacctcaaa gagcaagccc agaacctaga gattcaagac
    24001 tcagtcatct ttacagggat gattgctcct agtgagacgg ctctttacta taaagcggcg
    24061 gatttcttca tttcggcatc gacaagcgaa acgcaaggtt tgacctactt ggaaagctta
    24121 gccagtggaa cacctgtcat tgctcacgga aatccttatt tgaacaacct catcagtgat
    24181 aaaatgtttg gagccttgta ctatggagaa catgatttgg ctggtgctat tttggaagcc
    24241 ctgattgcaa caccagacat gaatgagcat accttatcag agaaattgta tgagatttca
    24301 gctgagaact ttgggaaacg agtgcatgag ttttatctgg atgccattat ttcaaataac
    24361 ttccagaaag atttggctaa agatgatacg gtcagtcagc gtatctttag gacagttttg
    24421 tatcttccgc aacaggtggt tgctgtacct gtaaaaggat ctagacgcat gttgaaggct
    24481 tcaaaaacac agttgatcag tatgagagac tattggaaag accatgaaga atagaaagag
    24541 gaacagctat gaaaaaaaca attaatgaga agcggtcgtg ataaaaagat tgcgggtgtt
    24601 tgtgctgggg tggcccatta tctggatatg gatccgacta tcgttcaagt catttggggt
    24661 gttcttactt gctgttacgg agctggaatt gtagcttaca ttattttatg gattatcgca
    24721 ccagtagcaa ctgactattg aaaactagct caattcatgc taagataata gaaaatagaa
    24781 tgtaacgaag gagagaaaaa tggcatttgg agataatgga aatcgtaaaa aaactatgtt
    24841 tgagaaaata accttgttta tcgtgattat catgctagta gcaagtttat tgggaatttt
    24901 tgcaactgca attggtgccc tcagtaatct ataaaataga ttcaagaaaa tttagtgact
    24961 gggatttccc agcccttttt taaagtgaga agaaataatg agtatgtttt tagatacagc
    25021 taagattaag gtcaaggctg gtaatggtgg cgatggtatg gttgcctttc gtcgtgaaaa
    25081 atatgtccct aatggaggcc cttggggtgg tgatggtggt cgtggaggca atgtggtctt
    25141 cgttgtagac gaaggactac gtaccttgat ggatttccgc tacaatcgtc atttcaaggc
    25201 tgattctggt gaaaaaggga tgaccaaagg gatgcatggt cgtggtgctg aggaccttag
    25261 agttcgagta ccacaaggta cgactgttcg tgatgcggag actggcaagg ttttaacaga
    25321 tttgattgaa catgggcaag aatttatcgt tgcccacggt ggtcgtggtg gacgtggaaa
    25381 tattcgtttc gcgacaccaa aaaatcctgc accggaaatc tctgaaaatg gagaaccagg
    25441 tcaggaacgt gagttacaat tggaactaaa aatcttggca gatgtcggtt tagtaggatt
    25501 cccatctgta gggaagtcaa cacttttaag tgttattacc tcagctaagc ctaaaattgg
    25561 tgcctaccac tttaccacta ttgtaccaaa tttaggtatg gttcgcaccc aatcaggtga
    25621 atcctttgca gtagccgact tgccaggttt gattgaaggg gctagtcaag gtgttggttt
    25681 gggaactcag tttctccgtc acatcgagcg tacacgtgtt atccttcaca tcattgatat
    25741 gtcagctagc gaaggccgtg atccatatga ggattaccta gctatcaata aagagctgga
    25801 gtcttacaat cttcgcctca tggagcgtcc acagattatt gtagctaata agatggacat
    25861 gcctgagagt caggaaaatc ttgaagaatt taagaaaaaa ttggctgaaa attatgatga
    25921 atttgaagag ttaccagcta tcttcccaat ttctggattg accaagcaag gtctggcaac
    25981 acttttagat gctacagctg aattgttaga caagacacca gaatttttgc tctacgacga
    26041 gtccgatatg gaagaagaag cttactatgg atttgacgaa gaagaaaaag cctttgaaat
    26101 tagtcgtgat gacgatgcga catgggtact ttctggtgaa aaactcatga aactctttaa
    26161 tatgaccaac tttgatcgtg atgaatctgt catgaaattt gcccgtcagc ttcgtggtat
    26221 gggggttgat gaagcccttc gtgcgcgtgg agctaaagat ggggatttgg tccgcattgg
    26281 taaatttgag tttgaatttg tagactagga gactggtatg ggagataaac cgatatcttt
    26341 ccgagatgcg gatggtaatt ttgtttccgc cgcagacgtt tggaatgaaa agaaattgga
    26401 agaactattt aatcgtctca atccaaatcg tgccttgaga ttggcacgaa ctaaaaagga
    26461 aaatccatct cagtaaagaa gctaaaaaat cccgtgcctc atcagacacg ggattttgtg
    26521 gtacgacagg catgtatagc aaactgaatc tggaatagca cagcatatct tctaaaatat
    26581 agtaaaatga aatgagaaca ggacaaatcg atcaggacag taaaatcgat ttctaacaat
    26641 gttttagaag cagagatgta ctattctagt ttcaatcaac tatattgtta taaattgatt
    26701 tgaatttcaa aattaaattg tttgattctt atttcaattt gttatagtat atctgatgtc
    26761 aaagttctcg gcgagtcaaa tagcgattcc caagcctgac tatcgtgagg tagcggatta
    26821 aaatggtctg gggatagacc gttttaagtc tgacgctgga aataagaatt gtcagaagaa
    26881 gggatagcga aatcgtggct ctacgaacag ggacgtgata ataaggcgta tatagcggat
    26941 aagagggcat caaactctaa agtccaaaaa ggtagtcgta acctatatgc gtaaatcacg
    27001 agagtaattg aattcgtact aagattttct attttcactg taacctttta acgcccttat
    27061 atcttgtata cacgaggaaa gatgtacgac ttatcccgtg aggtctatca ctataaagag
    27121 aaaacgacag atagaagtga tcctgagtca cggttatctg tctgatagga cggtatgtat
    27181 aaaacgcttc tgtgaactga gagaaggggg agaagttctt gctaaaattt agttgaacag
    27241 ccgtattccg atacttagat aagagatcta gtcttagctc ctactcagtt ttaggggata
    27301 aaaaaggggc aatagcgatt cgagaaagat tatactcttc gaaaatctct tcaaatcacg
    27361 tcaatatcgc cttgtcgtat gtgtaggata ctgactacgt cagttccatc tacaacctca
    27421 aaacagtgtt ttgagcaacc tgcggctagt ttcctagttt gatctttgat tttcattgag
    27481 tattagtaat tcagttacta actcgtcaac tctgatttat ccaataaaat tgaaaaggat
    27541 ggaaaaaagg ataaatttat gatatacttt attttgaaga ccttattaga aatcttgaaa
    27601 gagtattgaa aacttagaat gagaaaaatt gttatcaatg gtggattacc actgcaaggt
    27661 gaaatcacta ttagtggtgc taaaaatagt gtcgttgcct taattccagc tattatcttg
    27721 gctgatgatg tggtgacttt ggattgcgtt ccagatattt cggatgtagc cagtcttgtc
    27781 gaaatcatgg aattgatggg agctactgtt aagcgttatg acgatgtatt ggagattgac
    27841 ccaagaggtg ttcaaaatat tccaatgcct tatggtaaaa ttaacagtct tcgtgcatct
    27901 tactattttt atgggagcct cttaggccgt tttggtgaag cgacagttgg tctaccggga
    27961 ggatgtgatc ttggtcctcg tccgattgac ttacacctta aggcgtttga agctatgggt
    28021 gccactgcta gctacgaggg agataacatg aagttatctg ctaaagatac aggacttcat
    28081 ggtgcaagta tttacatgga tacggttagt gtgggagcaa cgattaatac gatgattgct
    28141 gcggttaaag caaatggtcg tactattatt gaaaatgcag cccgtgaacc tgagattatt
    28201 gatgtagcta ctctcttgaa taatatgggt gcccatatcc gtggggcagg aactaatatc
    28261 atcattattg atggtgttga aagattacat gggacacgtc atcaggtgat tccagaccgc
    28321 attgaagctg gaacatatat atctttagct gctgcagttg gtaaaggaat tcgtataaat
    28381 aatgttcttt acgaacacct ggaagggttt attgctaagt tggaagaaat gggagtgaga
    28441 atgactgtat ctgaagacag catttttgtc gaggaacagt ctaatttgaa agcaatcaat
    28501 attaagacag ctccttaccc aggctttgca actgatttgc aacaaccgct tacccctctt
    28561 ttactaagag cgaatggtcg tggtacaatt gtcgatacga tttacgaaaa acgtgtaaat
    28621 catgtttttg aactagcaaa gatggatgcg gatatttcga caacaaatgg tcatattttg
    28681 tacacgggtg gacgtgattt acgtggggcc agtgttaaag cgaccgactt aagagctggg
    28741 gctgcactag tcattgctgg gcttatggct gaaggtaaaa ctgaaattac caatatcgag
    28801 tttatcttac gtggttattc tgatattatc gaaaaattac gtaatttagg agcggatatt
    28861 agacttgttg aggattaaac cgtagaggtg tttatgaata tttggaccaa attagcaatg
    28921 ttttcttttt ttgaaacgga tcgcttgtat ttgcgtcctt tcttttttag tgatagtcag
    28981 gacttccgcg agatagcttc aaatccagaa aatcttcaat ttattttccc aacgcaggca
    29041 agtctggaag aaagtcaata tgcactggcc aattacttta tgaagtcccc tttgggagtg
    29101 tgggcaattt gtgaccagaa aaatcaacaa atgattggtt ctattaaatt tgagaagtta
    29161 gatgaaatca aaaaagaagc tgagcttggc tattttttga gaaaagatgc ttggtcgcaa
    29221 ggatttatga cagaggttgt tagaaaaatt tgtcagcttt cttttgagga atttggctta
    29281 aaacaattat ttatcattac ccaccttgaa aataaagcta gccaaagagt tgctcttaag
    29341 tctggattta gtttgttccg tcagtttaag ggaagtgatc gttacacaag aaaaatgcgg
    29401 gattatcttg aatttcggta tgtaaaagga gagttcaatg agtaagcatc aggaaattct
    29461 aagctatttg gaggaattac cagtaggtaa aagggtcagt gttcgtagca tttcgaatca
    29521 tctaggagtt agtgatggaa cagcctatcg ggctattaaa gaagctgaaa accgtggaat
    29581 tgtggagacc cgtcctagaa gtggaacaat tcgtgttaaa tcccagaaag ttgctataga
    29641 gagattaacg tttgctgaaa ttgcagaagt gacttcttct gaggttctgg ctgggcaaga
    29701 aggtttagag agagaattta gtaagttttc aattggtgcc atgactgaac aaaatatctt
    29761 gtcttacctt catgatgggg ggctcttgat tgtcggagac cgaacccgta ttcagttgct
    29821 agccttggaa aatgaaaatg cagttctggt tacaggggga tttcaggttc atgatgatgt
    29881 gcttaaactg gccaatcaaa aagggattcc tgttctaaga agtaagcatg atacctttac
    29941 cgtcgcgacc atgatcaata aagccttgtc aaatgtccaa atcaagactg atattctgac
    30001 agttgagaaa ctttatcgcc ctagtcatga gtatggtttt ctgagagaga cagatacagt
    30061 taaagattat ttggacttgg ttcgtaagaa tcgtagcagc cgtttccctg ttatcaatca
    30121 acatcaggtc gttgttggcg ttgtaaccat gagagacgct ggtgataaat caccaagcac
    30181 gacaattgat aaggttatgt ctcgtagtct atttttggtt ggattatcga caaatattgc
    30241 caatgtgagt caacggatga tcgcagaaga ctttgaaatg gtaccagttg ttcgaagcaa
    30301 tcaaactttg cttggcgttg tgacgcgacg agatgtcatg gagaagatga gccgttctca
    30361 agtttcggct ctaccaactt tttctgagca gattggacaa aagctctctt atcaccatga
    30421 tgaagtagtc attacagtgg aaccctttat gctagaaaaa aatggagttt tggctaatgg
    30481 tgtattggca gaaattctga cccacatgac ccaagattta gttgttaata gtggtcgcaa
    30541 tctcattatc gagcagatgc taatctactt tttgcaggct gttcagatag atgatatatt
    30601 gcgcattcag gcacggatta ttcatcatac gagacggtca gctataattg attacgatat
    30661 ttatcatggt caccagattg tttcaaaagc aaatgtgact gttaaaatta attagaaact
    30721 aggagaaaag atgataacat taaaatcagc tcgtgaaatc gaagctatgg acaaggctgg
    30781 tgattttcta gcaagtattc atataggctt acgtgatttg attaagccag gcgtagatat
    30841 gtgggaagtt gaagaatatg tccgccgtcg ttgtaaagaa gaaaatttcc ttccacttca
    30901 gattggggtt gacggtgcca tgatggacta tccttatgct acctgttgct ctcttaacga
    30961 tgaagtggct cacgctttcc ctcgtcatta tatcttgaaa gatggtgatt tgctcaaagt
    31021 tgatatggtt ttgggaggtc ccattgctaa atccgacctg aatgtctcaa aattaaactt
    31081 caacaatgtt gaacaaatga aaaaatacac tcagagctat tctggtggtt tagcagactc
    31141 atgttgggct tatgctgttg gtacaccgtc cgaagaagtc aaaaacttga tggatgtaac
    31201 caaagaagct atgtacaagg gtattgagca agctgttgtt ggaaatcgta tcggtgatat
    31261 cggtgcggct attcaagaat acgctgaaag tcgtggttac ggtgtagtgc gtgatttggt
    31321 tggtcatggt gttggcccaa ctatgcacga agaaccaatg gttcctaact atggtattgc
    31381 aggtcgtgga ctccgtcttc gtgaaggaat ggtcttaacc attgaaccaa tgatcaatac
    31441 aggcgattgg gaaattgata cagatatgaa aactggttgg gcgcataaga ccattgacgg
    31501 tggattgtca tgtcagtatg aacaccaatt tgtcattacg aaagatggac ctgttatctt
    31561 gactagccaa ggtgaagaag gaacttatta ataaaaagtg aaaagactac tggaagttta
    31621 ttttgataaa aaatccagta gatcttttca taataaaacg cattgtatca agtgttaggg
    31681 gctgatatca tgcgtttttc tgcttttaag attttttcca actctgtttg taagcgcatc
    31741 ataacaaagg gtctaggatt cagggctctc ctcctatata ctattagtaa agtaaaacta
    31801 agggaggata ttttagtgtc gcagtctatt gttcctgtag agattccaca atattgtcgt
    31861 tttgattcta aaaagagaaa tggaattctg tttaatgttc gtattgccaa tcttaaattt
    31921 acctttttta gattagactt cctgcgaaat aaaatatggt atagtagttc tatgaatgat
    31981 gaagcaagta aacaactaac cgat
//
LOCUS       DBEJAU010000023        31612 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC323 isolate 683620
            SAMN38261939-rid24807223.denovo.023, whole genome shotgun sequence.
ACCESSION   DBEJAU010000023 DBEJAU010000000
VERSION     DBEJAU010000023.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261939
            Sequence Read Archive: SRR26833919
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 31612)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 31612)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576303.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576303.1
            Genome Coverage       :: 154x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/19/2025 01:05:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,121
            CDSs (total)                      :: 2,078
            Genes (coding)                    :: 1,943
            CDSs (with protein)               :: 1,943
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 36
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 72 of 135
            Pseudo Genes (incomplete)         :: 63 of 135
            Pseudo Genes (internal stop)      :: 51 of 135
            Pseudo Genes (multiple problems)  :: 46 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..31612
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261939-rid24807223.denovo.023"
                     /strain="GPSC323"
                     /isolate="683620"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            <1..401
                     /locus_tag="ACL29Z_001091"
     CDS             <1..401
                     /locus_tag="ACL29Z_001091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000671992.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0069412.1"
                     /translation="SGILDEQIDKLSELSNLFTIKIETILTVISVVFTFIATLIEYGF
                     SLFLITLFFDKNKRNFGDILLSKNITLSFSILLCYLFNPSDIKFAYFSVLTVLLIGIT
                     NYARFKNLRLTVVFSVPFLFNAIMSIINSF"
     gene            781..2934
                     /gene="comA"
                     /locus_tag="ACL29Z_001092"
     CDS             781..2934
                     /gene="comA"
                     /locus_tag="ACL29Z_001092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000668284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide cleavage/export ABC transporter ComA"
                     /protein_id="HGR0069413.1"
                     /translation="MKFGKRHYRPQVDQMDCGVASLAMVFGYYGSYYFLAHLRELAKT
                     TMDGTTALGLVKVAEEIGFETRAIKADMTLFDLPDLTFPFVAHVLKEGKLLHYYVVTG
                     QDKDSIHIADPDPGVKLTKLPRERFEEEWTGVTLFMAPSPDYKPYKEQKNGLLSFIPI
                     LVKQRGLIANIVLATLLVTVINIVGSYYLQSIIDTYVPDQMRSTLGIISIGLVIVYIL
                     QQILSYAQEYLLLVLGQRLSIDVILSYIKHVFHLPMSFFATRRTGEIVSRFTDANSII
                     DALASTILSIFLDVSTVVIISLVLFSQNTNLFFMTLLALPIYTVIIFAFMKPFEKMNR
                     DTMEANAVLSSSIIEDINGIETIKSLTSESQRYQKIDKEFVDYLKKSFTYSRAESQQK
                     ALKKVAHLLLNVGILWMGAVLVMDGKMSLGQLITYNTLLVYFTNPLENIINLQTKLQT
                     AQVANNRLNEVYLVASEFEEKKTVEDLSLMKGDMTFKQVHYKYGYGRDVLSDINLIVP
                     QGSKVAFVGISGSGKTTLAKMMVNFYDPSQGEISLGGVNLNQIDKKALRQYINYLPQQ
                     PYVFNGTILENLLLGAKEGTTQEDILRAVELAEIREDIERMPLNYQTELTSDGAGISG
                     GQRQRIALARALLTDAPVLILDEATSSLDILTEKRIVDNLMALDKTLIFIAHRLTIAE
                     RTEKVVVLDQGKIVEEGKHADLLAQGGFYAHLVNS"
     gene            2947..4296
                     /gene="comB"
                     /locus_tag="ACL29Z_001093"
     CDS             2947..4296
                     /gene="comB"
                     /locus_tag="ACL29Z_001093"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000801614.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence pheromone export protein ComB"
                     /protein_id="HGR0069414.1"
                     /translation="MKPEFLESAEFYNRRYHNFSSSVIVPMALLLVFLLGFATVAEKE
                     MSLSTRATVEPSRILANIQSTSNNRILVNHLEENKLVKKGDLLVQYQEGAEGVQAESY
                     ASQLDMLKDQKKQLEYLQKSLQEGENHFPEEDKFGYQATFRDYISQAGSLRASTSQQN
                     ETIASQNAAASQTQAEIGNLISQTEAKIRDYQTAKSAMETGASLASQNLAYSLYQSYK
                     SQGEENPQTKVQAVAQVEAQISQLESSLATYRVQYAGSATQQAYASGLSSQLESLKSQ
                     HLAKVGQELTLLAQKILEAESGKKVQGNLLDKGKITASEDGVLHLNPETSDSSMVAEG
                     ALLAQLYPSLEREGKAKLTAYLSSKDVARIKVGDSVRYTTTHDAGNQLFLDSTITSID
                     ATATKTEKGNFFKIEAETNLTSEQAEKLRYGVEGRLQMITGKKSYLRYYLDQFLNKE"
     gene            4466..5173
                     /gene="purC"
                     /locus_tag="ACL29Z_001094"
     CDS             4466..5173
                     /gene="purC"
                     /locus_tag="ACL29Z_001094"
                     /EC_number="6.3.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000043309.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004639 -
                     phosphoribosylaminoimidazolesuccinocarboxamide synthase
                     activity [Evidence IEA];
                     GO_process: GO:0006164 - purine nucleotide biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylaminoimidazolesuccinocarboxamide
                     synthase"
                     /protein_id="HGR0069415.1"
                     /translation="MSKQLIYSGKAKDIYTTEDENLIISTYKDQATAFNGVKKEQIAG
                     KGVLNNQISSFIFEKLNAAGVATHFVEKLSDTEQLNKKVKIIPLEVVLRNYTAGSFSK
                     RFGVDEGIALETPIVEFYYKNDDLDDPFINDEHVKFLQIADDQQIAYLKEETRRINEL
                     LKVWFAEIGLKLIDFKLEFGFDKDGKIILADEFSPDNCRLWDADGNHMDKDVFRRGLG
                     ELTDVYEIVWEKLQGLK"
     gene            5230..8955
                     /locus_tag="ACL29Z_001095"
     CDS             5230..8955
                     /locus_tag="ACL29Z_001095"
                     /EC_number="6.3.5.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000361233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004642 -
                     phosphoribosylformylglycinamidine synthase activity
                     [Evidence IEA];
                     GO_process: GO:0006189 - 'de novo' IMP biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine synthase"
                     /protein_id="HGR0069416.1"
                     /translation="MDKRIFVEKKADFQVKSESLVRELQHNLGLSSLKSIRIVQVYDV
                     FDLVEDLFAPAEKHIFSEQVTDHVLDEVSVQADLANYAFFAIESLPGQFDQRAASSQE
                     ALLLLGSSSDVTVNTAQLYLVNKDIDATELEAVKNYLLNPVDSRFKDITIGIAKQEFS
                     ESDKTIPKLPFFESYTAEDFARYKAEQGMAMEVDDLLFIQDYFKSIGRVPTETELKVL
                     DTYWSDHCRHTTFETELKHIDFSASKFQKQLQSTYDKYIAMREELGRSEKPQTLMDMA
                     TIFGRYERANGRLDDMEVSDEINACSVEIEVDVDGVKEPWLLMFKNETHNHPTEIEPF
                     GGAATCIGGAIRDPLSGRSYVYQAMRISGAGDITAPISETRAGKLPQQVISKTATHGY
                     SSYGNQIGLATTYVREYFHPGFVAKRMELGAVVGAAPKGNVVREKPEAGDVIILLGGK
                     TGRDGVGGATGSSKVQTVESVETAGAEVQKGNAIEERKIQRLFRNGNVTRLIKKSNDF
                     GAGGVCVAIGELADGLEIDLNKVPLKYQGLNGTEIAISESQERMAVVVRPEDVDTFVA
                     ECNKENIDAVVVATVTEKPNLVMHWNGETIVDLERRFLDINGVRVVVDAKVVDKDVKL
                     PEERQTSAETLESDTLTVLSDLNHASQKGLQTIFDCSVGRSTVNHPLGGRYQLTPTEA
                     SVQKLPVQHGVTHTASVIAQGFNPYVAEWSPYHGAAYAVIEATARLVAAGANWSKARF
                     SYQEYFERMDKQAERFGQPVAALLGSIEAQIQLGLPSIGGKDSMSGTFEELTVPPTLV
                     AFGVTTADSRKVLSPEFKAVGENIYYIPGQALSAEIDFDLIKKNFAQFEASQADHKVT
                     SASAVKYGGVVESLALATFGNYIGAEVTLPELKTALTAQLGGFVFTSPEEIAGVEKIG
                     QTKADFTLTVNGVKLDGHKLDSAFQGTLEEVYPTEFTQAKELEEVPAVASDVVIKAKE
                     KVEKPVVYIPVFPGTNSEYDSAKAFEKEGAEVNLVPFVTLNEEAIVKSVETMVDNIDK
                     TNILFFAGGFSAADEPDGSAKFIVNILLNEKVRVAIDSFIARGGLIIGICNGFQALVK
                     SGLLPYGNFEDANSTSPTLFYNDANQHVAKMVETRIANTNSPWLAGVQVGDIHAIPVS
                     HGEGKFVVTAEEFAELRDNGQIFSQYVDFNGKPSMDSKYNPNGSVHAIEGITSKNGQI
                     IGKMGHSERYEDGLFQNIPGNKDQHLFASAVKHFTGK"
     gene            9048..10490
                     /gene="purF"
                     /locus_tag="ACL29Z_001096"
     CDS             9048..10490
                     /gene="purF"
                     /locus_tag="ACL29Z_001096"
                     /EC_number="2.4.2.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000220605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004044 - amidophosphoribosyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0009113 - purine nucleobase biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amidophosphoribosyltransferase"
                     /protein_id="HGR0069417.1"
                     /translation="MTYEVKSLNEECGVFGIWGHPDAAKLTYFGLHSLQHRGQEGAGI
                     LSNDQGQLKRHRDMGLLSEVFRNPANLDKLTGAGAIGHVRYATAGEASVDNIQPFLFR
                     FHDMQFGLAHNGNLTNTASLKKELEQRGAIFSATSDSEILAHLIRRSHNPSLMGKIKE
                     ALSLVKGGFAYILLFEDKLIAALDPNGFRPLSIGKMANGAVVVSSETCAFEVIGAEWI
                     RDLKPGEIVIIDDEGIQYDSYTDDTQLAVCSMEYIYFARPDSNIHGVNVHTARKRMGA
                     QLAREFKHEADIVVGVPNSSLSAAMGFAEESGLPNEMGLIKNQYTQRTFIQPTQELRE
                     QGVRMKLSAVSGVVKGKRVVMVDDSIVRGTTSRRIVQLLKEAGATEVHVAIGSPALAY
                     PCFYGIDIQTRQELIAANHTVEETRQIIGADSLTYLSIDGLIESIGIETDAPNGGLCV
                     AYFDGDYPTPLYDYEEDYRRSLEEKTSFYK"
     gene            10527..11549
                     /gene="purM"
                     /locus_tag="ACL29Z_001097"
     CDS             10527..11549
                     /gene="purM"
                     /locus_tag="ACL29Z_001097"
                     /EC_number="6.3.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009729529.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004641 -
                     phosphoribosylformylglycinamidine cyclo-ligase activity
                     [Evidence IEA];
                     GO_process: GO:0006189 - 'de novo' IMP biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine cyclo-ligase"
                     /protein_id="HGR0069418.1"
                     /translation="MTNKNAYAQSGVDVEAGYEVVERIKKHVARTERAGVMGALGGFG
                     GMFDLSKTGVKEPVLISGTDGVGTKLMLAIKYDKHDTIGQDCVAMCVNDIIAAGAEPL
                     YFLDYVATGKNEPAKLEQVVAGVAEGCVQAGAALIGGETAEMPGMYGEDDYDLAGFAV
                     GVAEKSQIIDGSKVVEGDVLLGLASSGIHSNGYSLVRRVFADYTGEEVLPELEGKKLK
                     EVLLEPTRIYVKAVLSLIKEELVNGIAHITGGGFIENVPRMFADDLAAEIDESKVPVL
                     PIFKALEKYGQIKHEEMFEIFNMGVGLMLAVSPENVERVKELLDEAVYEIGRIVKKEN
                     ESVIIK"
     gene            11546..12091
                     /gene="purN"
                     /locus_tag="ACL29Z_001098"
     CDS             11546..12091
                     /gene="purN"
                     /locus_tag="ACL29Z_001098"
                     /EC_number="2.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004644 - phosphoribosylglycinamide
                     formyltransferase activity [Evidence IEA];
                     GO_process: GO:0006189 - 'de novo' IMP biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylglycinamide formyltransferase"
                     /protein_id="HGR0069419.1"
                     /translation="MKKIAVFASGNGSNFQVIAEEFPVEFVFSDHRDAYVLERAKQLG
                     VLSYAFELKEFESKADYEAALVELLEEHQIDLVCLAGYMKIVGPTLLSAYEGRIVNIH
                     PAYLPEFPGAHGIEDAWNAGVGQSGVTIHWVDSGVDTGQVIKQVRVPRLADDTIDRFE
                     ARIHEAEYRLYPEVVKALFTD"
     gene            12175..12684
                     /locus_tag="ACL29Z_001099"
     CDS             12175..12684
                     /locus_tag="ACL29Z_001099"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000894002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanZ family protein"
                     /protein_id="HGR0069420.1"
                     /translation="MLESKKTTRYVFYVYLMLLTWGILFKFETNPEFIAFFLAPRYIN
                     WIPFSEPLIVDGKIVFAEMLFNLISFIPLGVCFPLIKTNLSSLRIVGTGFLISLLFEC
                     LQYILAIGITDITDLTLNTLGVCVGLLIYQIFIRVFKSQTRKWINILGMLSLGFAYLV
                     LLLLHLIGV"
     gene            12709..14253
                     /gene="purH"
                     /locus_tag="ACL29Z_001100"
     CDS             12709..14253
                     /gene="purH"
                     /locus_tag="ACL29Z_001100"
                     /EC_number="2.1.2.3"
                     /EC_number="3.5.4.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006146083.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA];
                     GO_function: GO:0003937 - IMP cyclohydrolase activity
                     [Evidence IEA];
                     GO_function: GO:0004643 -
                     phosphoribosylaminoimidazolecarboxamide formyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0006164 - purine nucleotide biosynthetic
                     process [Evidence IEA];
                     GO_process: GO:0006189 - 'de novo' IMP biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional
                     phosphoribosylaminoimidazolecarboxamide
                     formyltransferase/IMP cyclohydrolase"
                     /protein_id="HGR0069421.1"
                     /translation="MTKRVLISVSDKAGIVEFAQELKKLGWEIISTGGTKVALDNAGV
                     DTIAIDDVTGFPEMMDGRVKTLHPNIHGGLLARRDLDSHLEAAKDNKIELIDLVVVNL
                     YPFKETILKPDVTYADAVENIDIGGPSMLRSAAKNHASVTVVVDPADYAVVLDELAAN
                     GETSYETRQRLAAKVFRHTAAYDALIAEYFTAQVGESKPEKLTLTYDLKQPMRYGENP
                     QQDADFYQKALPTDYSIASAKQLNGKELSFNNIRDADAAIRIIRDFKDSPTVVALKHM
                     NPCGIGQADDIETAWDYAYESDPVSIFGGIVVLNREVDAATAEKMHGVFLEIIIAPSY
                     TDEALAILIKKKNLRILALPFNAQEASEVEAEYTGVVGGLLVQNQDVVKESPADWQVV
                     TKRQPTETEATALEFAWKAIKYVKSNGIIVTNDHMTLGVGPGQTNRVASVRLAIDQAK
                     DRLDGAVLASDAFFPFADNVEEIAKAGIKAIIQPGGSVRDQESIEAADKYGLTMVFTG
                     VRHFRH"
     gene            14375..15637
                     /gene="purD"
                     /locus_tag="ACL29Z_001101"
     CDS             14375..15637
                     /gene="purD"
                     /locus_tag="ACL29Z_001101"
                     /EC_number="6.3.4.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000772208.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004637 - phosphoribosylamine-glycine
                     ligase activity [Evidence IEA];
                     GO_process: GO:0009113 - purine nucleobase biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylamine--glycine ligase"
                     /protein_id="HGR0069422.1"
                     /translation="MKLLVVGSGGREHAIAKKLLESKDVEKVFVAPGNDGMTLDGLEL
                     VNISISEHSKLIDFAKTNDVAWTFIGPDDALAAGIVDDFNQAGLKAFGPTRAAAELEW
                     SKDFAKEIMVKYGVSTAAYGTFSDFEEAKAYIEKHGAPIVVKADGLALGKGVVVSETV
                     EQAVEAAHEMLLDNKFGDSGARVVIEEFFEGEEFSLFAFVNGDKFYIMPTAQDHKRAY
                     DGDKGPNTGGMGAYAPVPHLPQSVVDTAVDTIVKPVLEGMIKEGRPYLGVLYAGLILT
                     ADGPKVIEFNARFGDPETQIILPRLTSDFAQNITDILDSKEPNIMWTDKGVTLGVVVA
                     SKGYPLDYERGVELPAKTEGDVITYYAGAKFAENSRALLSNGGRVYMLVTTADTVKEA
                     QASIYQELYQQKIEGLFYRTDIGSKAIK"
     gene            15894..16010
                     /locus_tag="ACL29Z_001102"
     CDS             15894..16010
                     /locus_tag="ACL29Z_001102"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809271.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylaminoimidazole carboxylase"
                     /protein_id="HGR0069423.1"
                     /translation="MKERLDDNPIVQGNWKTLGFQFRHETPLVAAAVPHKLR"
     gene            16040..16528
                     /gene="purE"
                     /locus_tag="ACL29Z_001103"
     CDS             16040..16528
                     /gene="purE"
                     /locus_tag="ACL29Z_001103"
                     /EC_number="4.1.1.21"
                     /EC_number="5.4.99.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009567721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009320 - phosphoribosylaminoimidazole
                     carboxylase complex [Evidence IEA];
                     GO_function: GO:0004638 - phosphoribosylaminoimidazole
                     carboxylase activity [Evidence IEA];
                     GO_process: GO:0006189 - 'de novo' IMP biosynthetic
                     process [Evidence IEA];
                     GO_process: GO:0009152 - purine ribonucleotide
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="5-(carboxyamino)imidazole ribonucleotide mutase"
                     /protein_id="HGR0069424.1"
                     /translation="MKPVISIIMGSKSDWATMQKTAEVLDRFGVAYEKKVVSAHRTPD
                     LMFKHAEEARSRGIKIIIAGAGGAAHLPGMVAAKTTLPVIGVPVKSRALSGVDSLYSI
                     VQMPGGVPVATMAIGEAGATNAALFALRLLSVEDKSIADALANFAEEQGKIAEESSNE
                     LI"
     gene            16515..17606
                     /gene="purK"
                     /locus_tag="ACL29Z_001104"
     CDS             16515..17606
                     /gene="purK"
                     /locus_tag="ACL29Z_001104"
                     /EC_number="6.3.4.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000099033.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004638 - phosphoribosylaminoimidazole
                     carboxylase activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0006189 - 'de novo' IMP biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="5-(carboxyamino)imidazole ribonucleotide
                     synthase"
                     /protein_id="HGR0069425.1"
                     /translation="MSSSKTIGIIGGGQLGQMMAISAIYMGHKVIALDPAADCPTSRV
                     AEIIVAPYNDVDALRQLADRCDVLTYEFENVDADGLDAVIKDGQLPQGTDLLRISQNR
                     IFEKDFLSNKAQVTVAPYKVVTSSLDLADIDLSKNYVLKTATGGYDGHGQKVIRSEAD
                     LEAAYALADSADCVLEEFVNFDLEISVIVSGNGKEVTFFPVQENIHRNNILSKTIVPA
                     RISESLVDKAKAMAVRIAEQLNLSGTLCVEMFATDDDVIVNEIAPRPHNSGHYSIEAC
                     DFSQFDTHILGVLGAPLPVIKLHAPAVMLNVLGQHVEAAEQYVTENSSAHLHMYGKIE
                     AKHNRKMGHVTLFSDVPDSVDELGEGIDF"
     gene            17616..17843
                     /locus_tag="ACL29Z_001105"
     CDS             17616..17843
                     /locus_tag="ACL29Z_001105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006270103.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylaminoimidazole carboxylase"
                     /protein_id="HGR0069426.1"
                     /translation="MIQIIVNTFIEKDKTGAVVEVLYASADQDKVQAKYEELAAQYPE
                     NYLAIYDVPLDTDLNTLDHYPSVFIEKEEFE"
     gene            17906..19204
                     /gene="purB"
                     /locus_tag="ACL29Z_001106"
     CDS             17906..19204
                     /gene="purB"
                     /locus_tag="ACL29Z_001106"
                     /EC_number="4.3.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000572899.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004018 - N6-(1,2-dicarboxyethyl)AMP
                     AMP-lyase (fumarate-forming) activity [Evidence IEA];
                     GO_process: GO:0009152 - purine ribonucleotide
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="adenylosuccinate lyase"
                     /protein_id="HGR0069427.1"
                     /translation="MINRYSRPEMANIWSEENKYRAWLEVEILSDEAWAELGEIPKED
                     VALIRKKADFDIDRILEIEQETRHDVVAFTRAVSETLGEERKWVHYGLTSTDVVDTAY
                     GYLYKQANDIIRRDLENFTNIIADKAKEHKFTIMMGRTHGVHAEPTTFGLKLATWYSE
                     MKRNIERFEHAAAGVEAGKISGAVGNFANIPPFVEEYVCDKLGIRAQEISTQVLPRDL
                     HAEYFAVLASIATSIERMATEIRGLQKSEQREVEEFFAKGQKGSSAMPHKRNPIGSEN
                     MTGLARVIRGHMITAYENVALWHERDISHSSAERIITPDTTILIDYMLNRFGNIVKNL
                     TVFPENMIRNMNSTFGLIFSQRAMLTLIEKGMTREQAYDLVQPKTAYSWDNQVDFKPL
                     LEADSEVTSRLTQEEIDEIFNPVYYTKRVDDIFERLGLGD"
     gene            complement(19259..23125)
                     /gene="strH"
                     /locus_tag="ACL29Z_001107"
     CDS             complement(19259..23125)
                     /gene="strH"
                     /locus_tag="ACL29Z_001107"
                     /EC_number="3.2.1.52"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000679939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG-anchored beta-N-acetylhexosaminidase StrH"
                     /protein_id="HGR0069428.1"
                     /translation="MKHEKQQRFSIRKYAVGAASVLIGFAFQAQTVAADGVTPTTTEN
                     QPTIHTVSDSPQSSENRTEETPKAVLQPEAPKTVETETPATDKVASLPKTEEKPQEEV
                     SSTPSDKAEVVTPTSAEKETANKKAEEASPKKEEAKAEADKLETEAGKERATTVNEKL
                     AKKKIVSIDAGRKYFSPEQLKEIIDKAKHYGYTDLHLLVGNDGLRFMLDDMSITANGK
                     TYASDDVKRAIEKGTNDYYNDPNGNHLKESQMTDLINYAKDKGIGLIPTVNSPGHMDA
                     ILNAMKELGIQNPNFSYFGKKSARTVDLDNEQAVAFTKALIDKYAAYFAKKTEIFNIG
                     LDEYANDATDAKGWSVLQADKYYPNEGYPVKGYEKFIAYANDLARIVKSHGLKPMAFN
                     DGIYYNSDTSFGSFDKDIIVSMWTGGWGGYDVASSKLLAEKGHQILNTNDAWYYVLGR
                     NADGQGWYNLDQGLNGIKNTPITSVPKTEGADIPIIGGMVAAWADTPSARYSPSHLFK
                     LMRHFANANAEYFAADYESAEQALNEVPKDLNRYTAESVAAVKEAEKAIRSLDSNLSR
                     AQQDTIEQAIAKLQETVNNLTLTPEAQKEEEAKREVEKLAKNKVISIDAGRKYFTLDQ
                     LKRIVDKASELGYSDVHLLLGNDGLRFLLNDMTITANGKTYASDDVKKAIIEGTKAYY
                     DDPNGTALTQAEVTELIEYAKSKDIGLIPAINSPGHMDAMLVAMEKLGIKNPQAHFDK
                     VSKTTMDLKNEEAMNFVKALIGKYMDFFAGKTKIFNFGTDEYANDATSAQGWYYLKWY
                     QLYGKFAEYANTLAAMAKERGLQPMAFNDGFYYEDKDDVQFDKDVLISYWSKGWWGYN
                     LASPQYLASKGYKFLNTNGDWYYVIGNHKQDEAYPLSKAVENSGKVPFNQLASTKYPE
                     VDLPTVGSMLSIWADRPSAEYKEEEIFELMTAFADHNKDYFRANYNALREELAKIPTN
                     LEGYSKESLEALDAAKTALNYNLNRNKQAELDTLVANLKAALQGLKPAATHSGSLDEN
                     EVAANVETRPELITRTEEIPFEVIKKENPNLPAGQENIITAGVKGERTHYISVLTENG
                     KTTETVLDSQVTKEVINQVVEVGAPVTHKGDESGLAPTTEVKPRLDIQKEEIPFTTVT
                     RENPLLLKGKTQVITKGVNGHRSNFYSVSTSADGKEVKTLVNSVVAQEAVTQIVEVGT
                     MVTHVGDENGQAAIAEEKPKLEIPSQPAPSTAPAEESKALPQDPAPVVTEKKLPETGT
                     HDSAGLVVAGLMSTLAAYGLTKRKED"
     gene            complement(23440..24156)
                     /locus_tag="ACL29Z_001108"
     CDS             complement(23440..24156)
                     /locus_tag="ACL29Z_001108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001007200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HGR0069429.1"
                     /translation="MAIPKYQYIKDELKNKIISGQFSSGDKFYTEAELISMYDVSSIT
                     VVRALNDLAKDGYIVRQQGKGTFVSRARKHKLVEFSDIELFNAKDDKVTVLSIERGNK
                     LVYLEKLGLRGDQFYYKIERIRESNGVVYIYHTSYIPEQYINANYPNLEYYSSIYNRF
                     KLDYHIHMNDEHFEEINEIVFPTPEHAASVLGVDEQFPTVLQTKITKLESTGQVLEYS
                     ETYKRSDYYKIKFISCDRDH"
     gene            24505..26292
                     /locus_tag="ACL29Z_001109"
     CDS             24505..26292
                     /locus_tag="ACL29Z_001109"
                     /EC_number="3.2.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262529.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-galactosidase"
                     /protein_id="HGR0069430.1"
                     /translation="MTRFEIRDDFYLDGKSFKILSGAIHYFRVPPEDWYHSLYNLKAL
                     GFNTVETYVAWNLHEPREGEFHFEGDLDLEKFLQIAQDLGLYAIVRPSPFICAEWEFG
                     GLPAWLLTKNMRIRSSDPAYIEAVGRYYDQLLPRLVPRLLDNGGNILMMQVENEYGSY
                     GEDKAYLRAIRQLMEECGVTCPLFTSDGPWRATLKAGTLIEEDLFVTGNFGSKAPYNF
                     SQMQEFFDEHGKKWPLMCMEFWDGWFNRWKEPIITRDPKELADAVREVLEQGSINLYM
                     FHGGTNFGFMNGCSARGTLDLPQVTSYDYDALLDEEGNPTAKYLAVKKMMATHFSEYP
                     QLEPLYKESMELDAIPLVEKVSLFETLDSLSSPVESLYPQKMEELGQSYGYLLYRTET
                     NWDAEEERLRIIDGRDRAQLYVDGQWVKTQYQTEIGEDIFYQGKKKGLSRLDILIENM
                     GRVNYGHKFLADTQRKGIRTGVCKDLHFLLNWKHYPLPLDNPEKIDFSKGWTQGQPAF
                     YAYDFTVEEPKDTYLDLSEFGKGVAFVNGQNLGRFWNVGPTLSLYIPHSYLKEGANRI
                     IIFETEGQYKEEIHLTRKPTLKHIKGENL"
     gene            26289..26765
                     /locus_tag="ACL29Z_001110"
     CDS             26289..26765
                     /locus_tag="ACL29Z_001110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006155184.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HGR0069431.1"
                     /translation="MTIVGCRIDGRLIHGQVANLWAGKLNVSRIMVVDDEVVNNDIEK
                     SGLKLATPPGVKLSILPIEKAAANILAGKYDSQRLFIVARKPDRFLGLVEAGVPLETL
                     NVGNMSQTPETRSITRSINVVDKDVEDFHKLAEKGVKLTAQMVPNDPISDFLSLLK"
     gene            26793..27698
                     /locus_tag="ACL29Z_001111"
     CDS             26793..27698
                     /locus_tag="ACL29Z_001111"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006149155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS
                     mannose/fructose/sorbose/N-acetylgalactosamine transporter
                     subunit IIC"
                     /protein_id="HGR0069432.1"
                     /translation="MIQWWQILLLTLYSAYQICDELTIVSSAGSPVFAGFITGLIMGD
                     VTTGLLIGGNLQLFVLGVGTFGGASRIDATSGAVLATAFSVSQGIDAPLAITTIAVPV
                     AALLTYFDVLGRMTTTFFAHRVDAAIERFDYKGIERNYLLGAIPWALSRALPVFFALA
                     FGGAFVQSVVDFVEAYKWVADGLTLAGRMLPGLGFAILLRYLPVKRNLHYLAMGFGLT
                     AMLTVLYSYVTGLGGAVAGIVGTLPAEVAEKIGFVNNFKGLSMIGISIVGIFLAVLHF
                     KNSQKVVVAAPSTPSESGEIEDDEF"
     gene            27685..28500
                     /locus_tag="ACL29Z_001112"
     CDS             27685..28500
                     /locus_tag="ACL29Z_001112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000185291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HGR0069433.1"
                     /translation="MTNSNYKLTKEDFNQINKRSLFTFQLGWNYERMQASGYLYMILP
                     QLRKMYGDGTPELKEMMKVHTQFFNTSPFFHTIIAGFDLAMEEKDGVGSKDAVNGIKT
                     GLMGPFAPLGDTIFGSLVPAIMGSVAATMAIAGQPWGIFLWIAVAVAYDIFRWKQLEF
                     AYKEGVNLINNMQSTLTALIDAASVLGVFMMGALVATVINFEISYKLPIGEKMIDFQD
                     ILNQIFPRLLPAIFTAFIFWLLGKKGMNSTKAIGIIIVLALALSALGHFALGM"
     gene            28507..28911
                     /locus_tag="ACL29Z_001113"
     CDS             28507..28911
                     /locus_tag="ACL29Z_001113"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007284837.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HGR0069434.1"
                     /translation="MTKSLILVSHGRFCEELRGSTEMIMGPQDNIYTVALLPEDSPEE
                     FTAKFEAVIEGLDDFLVFADLLGGTPCNVVSRLIMEGRDIDLYAGMNLPMVIEFINAS
                     LTGADADYKSRAAESIVKVNDLLAGFDDDEDE"
     gene            29210..30376
                     /locus_tag="ACL29Z_001114"
     CDS             29210..30376
                     /locus_tag="ACL29Z_001114"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004257942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0097367 - carbohydrate derivative binding
                     [Evidence IEA];
                     GO_process: GO:1901135 - carbohydrate derivative metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HGR0069435.1"
                     /translation="MLHYTKEDLLELGAEITTREIYQQPDVWREAFEFYQAKREEIAA
                     FLQEIADKHDYIKVILTGAGTSAYVGDTLLPYFKEVYDERKWNFNAIATTDIVANPAT
                     YLKKDVATILVSFARSGNSPESVATVDLAKSLVDELYQVTITCATDGKLALQAHGDDR
                     NLLLLQPAVSNDAGFAMTSSFTSMMLTALLVFDPTEFAVKSERFEVVSSLARKVLDKA
                     EDVKELVDLDFNRVIYLGAGPFFGLAHEAQLKILELTAGQVATMYESPVGFRHGPKSL
                     INDNTVVLVFGTTTDYTRKYDLDLVREVAGDQIARRVVLLSDQAFGLENVKEVALGCG
                     GVLNDIYRVFPYIVYAQLFALLTSLKVENKPDTPSPTGTVNRVVQGVIIHEYQK"
     gene            30492..31529
                     /locus_tag="ACL29Z_001115"
     CDS             30492..31529
                     /locus_tag="ACL29Z_001115"
                     /EC_number="5.1.3.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000649444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016857 - racemase and epimerase activity,
                     acting on carbohydrates and derivatives [Evidence IEA];
                     GO_function: GO:0030246 - carbohydrate binding [Evidence
                     IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aldose epimerase family protein"
                     /protein_id="HGR0069436.1"
                     /translation="MKAYTERVFGNVEGEDVLAYRFETDGGYQLEVMTYGATILRYVA
                     PDKAGNFANVILGFDDFDSYVGNSPKHGASVGPVAGRIAGATFELNGKTYDLEVNNAS
                     NCNHSGSTGWDSSLFEVEEVSDHGLTLYTERTDGTGGFPGNLKIWISYHLEETGAYEI
                     SYKVTTDQDTLVNPTNHSYFNLSGDFTQTIDRHVFQLNTEGIYSIAPDGVPAKTPEAN
                     RDVVKHVYNGTLLKDIFAEEDEQIQLASGLDHPFALPAGHDNAGFLYDQNSGRFLLFK
                     TEAPCFVVYTANFVDESVIIGGQPMLQHNGIALEAQALPDAIHSDLKGQVILKAGQTF
                     TSKTRYELVVK"
BASE COUNT         8679 a         6183 c         7379 g         9371 t
ORIGIN      
        1 agtcgggaat tttagatgaa caaattgata aattatctga actatctaat ctttttacaa
       61 ttaaaataga aacaatattg acagtgattt ctgttgtttt cacatttata gcaactctta
      121 ttgaatatgg attttctctc tttctgatta cattattttt tgataagaat aagaggaact
      181 ttggagatat tcttttatct aaaaatataa ccttaagttt tagcatttta ctttgttatt
      241 tatttaatcc atcggatata aagtttgcct atttcagcgt attgacagta ttactaattg
      301 ggataacaaa ttatgcgaga tttaaaaatt taagattgac agtagtgttt tctgtaccat
      361 ttttatttaa tgctataatg tctattataa atagttttta gaaatactaa aatttttttc
      421 tttacttaat aatgatatga aatcatttcg gttttgttaa cttgtaattc ttatattttc
      481 taggtagaac gtttgttctg cctatttttt tatccaaaaa gtgcagttgg gagggagata
      541 ggctcatttg ggaaggaagt ccagtttttg tttagtgatt ggggtaagat agttgttatc
      601 agatgagttt atactcttcg aaaatcaaat tcaaaccacg tcaacgtcgc cttgccgtat
      661 atatgtgact gacttcgtca gtcctatcta caacctcaaa acagtgtttt gagcagcctg
      721 cggctagttt cctagtttgc tctttgattt tcattgagta ttagggaaaa ggagatgaat
      781 atgaaatttg ggaaacgtca ctatcgtccg caagtggatc agatggactg cggtgtagct
      841 tcattagcca tggtttttgg ctactatggt agttattatt ttttggctca cttgcgagaa
      901 ttggctaaga cgaccatgga tgggacgacg gctttgggct tggtcaaggt ggcagaggag
      961 attggttttg agacgcgagc cattaaggcg gatatgacgc tttttgactt gccggatttg
     1021 acttttcctt ttgttgccca tgtgcttaag gaagggaaat tgctccacta ctatgtggtg
     1081 actgggcagg ataaggatag cattcatatt gccgatccag atcccggggt gaagttgact
     1141 aaactgccac gtgagcgttt tgaggaagaa tggacaggag tgactctttt tatggcacct
     1201 agtccagact ataagcctta taaggaacaa aaaaatggtc tgctctcttt tatccctata
     1261 ttagtgaagc agcgtggctt gattgccaat atcgttttgg caacactctt ggtaaccgtg
     1321 attaacattg tgggttctta ttatctgcag tctatcattg atacctatgt gccagatcag
     1381 atgcgttcga cactagggat tatttctatt gggctagtca tcgtctacat cctccagcaa
     1441 atcttgtctt acgctcagga gtatctcttg cttgttttgg ggcaacgctt gtcgattgac
     1501 gtgattttgt cctatatcaa gcatgttttt cacctcccta tgtccttttt cgcgacacgc
     1561 aggacagggg aaattgtgtc tcgtttcacg gatgctaaca gtattatcga tgcgctggct
     1621 tcgaccattc tttcgatttt cctagatgtg tcaacagttg tcattatttc ccttgtttta
     1681 ttttcacaaa ataccaatct ctttttcatg actttattgg cgcttcctat ctacacagtg
     1741 attatctttg cctttatgaa gccgtttgaa aagatgaatc gggacaccat ggaagccaat
     1801 gcggttctgt cttcttctat cattgaggac atcaacggta ttgagactat caagtccttg
     1861 accagtgaaa gtcagcgtta ccaaaaaatt gacaaggaat ttgtggatta tctgaagaaa
     1921 tcctttacct atagtcgagc agagagtcag caaaaggctc tgaaaaaggt tgcccatctc
     1981 ttacttaatg tcggcattct ctggatgggg gctgttctgg tcatggatgg caagatgagt
     2041 ttggggcagt tgattaccta taataccttg ctggtttact ttaccaatcc tttggaaaat
     2101 atcatcaatc tgcaaaccaa gcttcagaca gcgcaggttg ccaataaccg tctaaatgaa
     2161 gtgtatctag tagcttctga gtttgaggag aagaaaacag ttgaggattt gagcttgatg
     2221 aagggagata tgaccttcaa gcaggttcat tacaagtatg gctatggtcg agacgtcttg
     2281 tcggatatca atttaatcgt tccccaaggg tctaaggtgg cttttgtggg gatttcaggg
     2341 tcaggtaaga cgactttggc caagatgatg gttaattttt acgacccaag tcaaggggag
     2401 attagtctgg gtggtgtcaa tctcaatcag attgataaaa aagccctgcg ccagtacatc
     2461 aactatctgc ctcaacagcc ctatgtcttt aacggaacga ttttggagaa tcttcttttg
     2521 ggagccaagg aggggacgac acaggaagat atcttacggg cggtcgaatt ggcagagatt
     2581 cgagaggata tcgagcgcat gccactgaat taccagacag aattgacttc ggatggggca
     2641 gggatttcag gtggtcaacg tcagagaatc gctttggcgc gtgctctctt gacagatgcg
     2701 ccggtcttga ttttggatga ggcgactagc agtttggata ttttgacaga gaagcggatt
     2761 gtcgataatc tcatggcttt ggacaagacc ttgattttca ttgctcaccg cttgactatt
     2821 gctgagcgaa cagagaaggt agttgtcttg gatcagggca agattgtcga agaaggaaag
     2881 catgctgatt tgcttgcaca gggtggcttt tacgcccatt tggtcaatag ctagaaagag
     2941 gagaggatga aaccagaatt tttagaaagt gcggagtttt ataatcgtcg ttaccataat
     3001 ttttccagta gtgtgattgt acccatggcc cttctgctcg tgtttttact tggctttgca
     3061 actgttgcag aaaaggagat gagtttgtcc actagagcta ctgtcgaacc tagtcgtatc
     3121 cttgcaaata tccagtcaac tagcaacaat cgtattcttg tcaatcattt ggaagaaaat
     3181 aagctggtta agaaggggga tcttttggtt caataccaag aaggggcaga gggtgtccaa
     3241 gcggagtcct atgccagtca gttggacatg ctaaaggatc aaaaaaagca attggagtat
     3301 ctgcaaaaga gcctgcaaga aggggagaac cactttccag aggaggataa gtttggctac
     3361 caagccacct ttcgcgacta catcagtcaa gcaggcagtc ttagggctag tacatcgcaa
     3421 caaaatgaga ccatcgcgtc ccagaatgca gcagctagcc aaacccaagc cgaaatcggc
     3481 aacctcatca gtcaaacaga ggctaaaatt cgcgattacc agacagctaa gtcagctatg
     3541 gaaacaggtg cttccttggc cagtcagaat ctagcctact ctctttacca gtcctacaag
     3601 tctcagggcg aggaaaatcc ccaaactaag gttcaggcag ttgcacaggt tgaagcacag
     3661 atttctcagt tagaatctag tcttgctact taccgtgtcc agtatgcagg ttcagctacc
     3721 cagcaagcct atgcgtcagg gttaagcagt caattggaat cccttaaatc ccaacatttg
     3781 gcaaaggttg gtcaggaatt gacccttcta gcccagaaaa tcttggaggc agagtcaggt
     3841 aagaaggtac agggaaatct tttagacaag gggaaaatta cggcgagtga ggatggggtg
     3901 cttcatctta atcctgagac cagtgattct agcatggttg cagaaggtgc cctactagcc
     3961 caactttatc catctttgga aagagaaggg aaagccaaac tcacagccta tctaagttca
     4021 aaagatgtag caagaatcaa ggtcggtgat tctgttcgct atactacgac tcatgatgcc
     4081 gggaatcaac ttttcctaga ttctactatt acaagtattg atgcgacagc tactaagact
     4141 gagaaaggga atttctttaa aatcgaggcg gagactaatc taacttcgga gcaggctgaa
     4201 aaacttaggt acggggtgga aggccgcttg cagatgatta cgggcaagaa aagttatcta
     4261 cgttattatt tggatcaatt tttgaacaaa gagtaatgtt cgtgttttta gagttaaata
     4321 atttttaaac tgtgagaaag attcttcttg cagttttttc tttacaattt ttgaaaaaca
     4381 tctgctattt attcggttaa attcttgtgt tttttggttt tttgtggtaa aatgtgctca
     4441 agtaatacga aaggcgaact ttaaaatgtc aaaacaattg atctattcgg gaaaagctaa
     4501 agatatctat acaactgagg atgaaaatct tattatttca acttacaagg accaggcgac
     4561 tgctttcaat ggtgtcaaga aggagcagat tgcaggtaag ggagtcttga ataatcagat
     4621 ttcatctttt atttttgaga aattaaatgc ggctggtgtg gcgactcact ttgtggagaa
     4681 actttcagac acggaacaac tcaataaaaa ggttaagatt attcctttgg aagtcgtgct
     4741 ccgcaactat actgctggtt ccttttcaaa acgttttggt gtggatgagg gaatcgcctt
     4801 ggagactccg attgtcgaat tttactacaa aaatgatgat ttggatgatc catttatcaa
     4861 tgatgagcat gtaaaattcc tacagattgc ggatgaccag cagattgcct acttgaagga
     4921 agaaacgcgt cgtatcaatg aactattgaa agtctggttt gctgagattg ggcttaaatt
     4981 gattgacttt aagctagagt tcggttttga caaggatggc aagattatct tggcagacga
     5041 attttcacca gataactgcc gcttgtggga tgctgatggc aaccacatgg ataaggatgt
     5101 tttccgtaga ggattgggag aactaaccga cgtttatgag attgtttggg aaaagttgca
     5161 gggtttaaaa taacaacctc aaggctgttt gggaatattg caagagctga aataaaggaa
     5221 taagaattga tggataaacg tatttttgtt gaaaaaaagg ctgattttca ggtcaagtca
     5281 gagagtttgg ttagagagct ccagcacaac ttgggactgt caagcttgaa aagtattcgt
     5341 attgtgcaag tatatgatgt atttgacttg gttgaggact tgtttgcacc tgcagagaag
     5401 cacattttct ctgagcaggt aaccgaccat gttttagatg aagtatctgt gcaggcggat
     5461 cttgctaact atgctttctt tgccattgaa agtctaccag ggcagtttga ccagcgtgca
     5521 gcttcgtcac aggaagcctt gcttttgttg ggaagttcga gtgacgtgac agtcaacaca
     5581 gcccaacttt acttggtgaa taaagatatt gatgcgactg agttggaagc tgtcaaaaac
     5641 tacctgctca atccagttga ttctcgtttc aaggatatca cgatagggat tgccaagcag
     5701 gagttttcag agtcagacaa gaccattcca aaattgcctt tctttgaaag ctatacagca
     5761 gaagactttg ctcgctacaa ggccgaacaa gggatggcca tggaagtgga tgatttgctc
     5821 tttatccaag actactttaa gtcaatcggg cgcgtgccaa ctgagactga actcaaggtt
     5881 ttggacactt actggtctga ccactgccgt catacgactt ttgagacaga gttgaaacac
     5941 atcgactttt cagcttctaa atttcaaaag caattgcagt caacctatga caagtatatt
     6001 gccatgcgcg aggaattagg tcggtctgaa aaaccacaaa ccttgatgga tatggcgact
     6061 attttcggtc gttatgagcg tgctaatgga cgattggatg atatggaagt ctctgacgaa
     6121 atcaatgcct gctcagttga aattgaagtg gacgttgatg gtgtcaagga accttggctc
     6181 ctcatgttta aaaacgaaac tcacaaccat ccaacagaaa ttgagccatt tggtggagcg
     6241 gctacctgta tcggtggagc tattcgtgat ccgttgtcag gccgttccta tgtttaccaa
     6301 gccatgcgta tttcaggtgc tggtgatatt acagcaccga tttcggaaac tcgtgctggg
     6361 aaattgccac aacaagtcat ttctaaaaca gcaactcatg gttattcttc atatggtaac
     6421 cagattgggc ttgccacaac ctacgttcgt gaatacttcc acccaggctt tgtagctaaa
     6481 cgtatggaac ttggtgccgt tgttggtgcg gctcccaagg gcaatgttgt ccgtgaaaaa
     6541 cctgaagcag gtgatgtgat catccttctc ggaggtaaaa caggtcgtga tggtgtcggt
     6601 ggtgcgacgg gctcttctaa ggttcaaaca gttgagtctg tagagactgc tggtgctgag
     6661 gttcaaaaag gaaatgccat cgaagaacgc aagattcagc gcctcttccg taatggcaat
     6721 gtcactcgtc tgatcaagaa gtccaatgac tttggggcag gcggtgtctg tgtggctatc
     6781 ggtgaattgg cagacggtct tgaaatcgac ctcaacaagg tgcctcttaa ataccagggc
     6841 ttgaatggta cagaaattgc catctctgaa tcacaagaac ggatggcggt cgtggttcgt
     6901 cctgaagatg tggatacctt cgttgccgaa tgtaacaaag aaaatattga tgctgttgtg
     6961 gtggcgacag taactgaaaa accaaatctt gtcatgcact ggaatggtga gacaatcgtt
     7021 gacttggagc gtcgtttcct tgacatcaat ggtgtgcgcg tggttgtcga tgccaaagtt
     7081 gtggacaagg atgtcaaact cccagaagag cgtcaaacat ctgctgaaac actggaatca
     7141 gataccctta cggttctatc tgacctcaac catgcaagtc aaaaaggatt acagactatc
     7201 tttgactgct ctgttggacg ctcaacggtt aatcacccac ttggtggtcg ttaccaactc
     7261 acaccaactg aggcatctgt gcagaaattg ccagttcaac acggtgtgac tcatactgcg
     7321 tcggtcattg ctcaaggttt caacccatat gtagctgaat ggtctccata ccacggtgct
     7381 gcttatgcgg ttatcgaagc aactgctcgt ttggtggctg ctggtgccaa ctggtccaag
     7441 gctcgtttct cttaccaaga atatttcgag cgtatggaca agcaagcaga gcgttttggt
     7501 cagccagtag ccgctcttct aggctctatt gaagctcaga ttcaacttgg cttgccatct
     7561 atcggtggta aggactccat gtctggtacc tttgaagaat tgaccgttcc gccaaccttg
     7621 gttgcctttg gggtgacgac ggcagatagc cgtaaggtgc tctctccaga atttaaagct
     7681 gttggggaaa atatctacta catcccaggt caagccctct ctgcagagat tgattttgac
     7741 ttgattaaga aaaattttgc tcagtttgaa gcaagccaag ctgaccataa agtgacatct
     7801 gcatcagctg tcaaatacgg tggtgtagtt gaaagtttgg ctcttgctac ctttggaaac
     7861 tatattggtg cagaggtgac cttgcctgaa cttaaaacag ctttgacagc tcaattaggc
     7921 ggctttgtct tcacatctcc tgaagaaatt gctggagtag agaagattgg acaaacgaaa
     7981 gcagacttta cactgactgt caacggtgtg aagctagatg gacacaagct tgacagtgca
     8041 tttcaaggga cattggaaga agtttaccca acagaattta cccaagcgaa agaactagaa
     8101 gaagtaccag ctgtggcatc agatgttgtg attaaagcca aagaaaaggt tgaaaaacct
     8161 gtggtttaca tcccagtctt tccaggaacc aactcagaat atgattcagc taaggccttc
     8221 gaaaaagaag gtgcagaggt caatttggtg ccattcgtga ccttgaatga agaagctatt
     8281 gtcaagtcag ttgaaactat ggttgacaat atcgacaaga ctaatattct cttctttgcc
     8341 ggtggattct cggctgcgga tgaaccagat ggttcagcta agtttatcgt caatatcctg
     8401 cttaatgaaa aagtacgtgt ggctattgat agctttatcg cccgtggtgg cttgattatc
     8461 ggtatttgta atggattcca agccttagtc aaatcgggtc tcctaccata cggaaacttt
     8521 gaagatgcta acagtactag tccaaccctc ttctacaatg atgccaacca acacgtggcc
     8581 aagatggtgg aaactcgcat tgccaatacc aactcaccat ggttggctgg tgtgcaagtg
     8641 ggcgatatcc acgctattcc tgtttcgcac ggtgaaggga agtttgtcgt gacggctgag
     8701 gaatttgcag agctccgtga caatggacaa attttcagcc aatacgttga ctttaacggt
     8761 aaaccaagta tggattctaa gtacaatccg aatggttctg tccatgccat cgaaggaatt
     8821 accagcaaga atggtcaaat catcggtaag atgggccact cagaacgtta tgaggatggt
     8881 cttttccaaa atatcccagg caataaagac caacacctgt tcgcatcagc ggttaaacat
     8941 ttcactggaa aataagactt acagattttc taatagatag tatcagtaat gtaaaagtca
     9001 tgtaaatcta gctcttgatg attacaaatg aaaattaggt ataaaaaatg acatacgaag
     9061 taaaatctct taatgaagaa tgtggtgttt tcggtatttg gggacatcca gatgctgcta
     9121 agttgaccta ttttggactc cacagtcttc aacaccgtgg tcaggagggg gcaggaatcc
     9181 tctccaacga tcaaggacaa ctgaagcgcc atcgtgacat ggggctttta tcagaagttt
     9241 tcagaaatcc agctaatttg gataaattga caggagctgg tgcgattggg catgtgcgtt
     9301 atgcgactgc tggcgaagct tctgtagata acatccagcc cttcctcttc cgttttcacg
     9361 atatgcagtt tggcttggct cataatggaa atctgaccaa tacagcctct ctcaagaaag
     9421 aactggaaca aagaggagca attttcagcg cgacttcgga ctctgaaatc ttggctcacc
     9481 tcattcgtcg cagtcataat cctagcctga tgggcaaaat caaggaagcg ctcagccttg
     9541 tcaaaggtgg ttttgcctat atcttgctgt ttgaggacaa gttgattgcg gctcttgacc
     9601 caaatggatt ccgaccgctt tcgattggta aaatggctaa tggagcagtt gttgtatctt
     9661 ctgaaacctg tgcttttgag gtcattggtg ccgagtggat tcgtgatttg aagccaggtg
     9721 agattgtgat cattgatgac gagggcattc agtatgacag ctatacagat gatacccagt
     9781 tggcggtttg ttctatggag tatatctact ttgctcgccc tgattctaat atccacggtg
     9841 tcaatgtcca tacggcacgt aagagaatgg gagcacaatt ggcgcgagaa tttaagcatg
     9901 aggcagatat tgtagttggt gtgcccaatt cttccctaag cgcggctatg ggatttgcgg
     9961 aagaatcagg cttaccaaat gaaatgggtc tgatcaaaaa ccaatacacc cagcgaactt
    10021 ttatccaacc gactcaagaa ttgcgggagc aaggagtgcg gatgaaactg tctgctgttt
    10081 cgggtgttgt caaaggcaaa cgtgtggtca tggtggatga ttccattgta cgtggaacaa
    10141 cctctcgtcg tatcgttcag ctcttgaaag aagcgggtgc gactgaggtt cacgttgcca
    10201 ttggaagtcc tgcactagcg tatccatgtt tctacgggat tgatatccag acccgtcagg
    10261 agctgattgc agccaatcat acggtcgaag aaactcgcca aatcattggt gcggacagtc
    10321 tgacttatct ttcaattgat ggcttgattg agtcgattgg tatcgaaaca gatgcgccga
    10381 acggtggtct ctgtgtcgct tactttgacg gtgactaccc aacgcctctc tatgactacg
    10441 aagaagacta tcgtagaagt ttggaagaaa agaccagttt ttacaagtag gcgacagatt
    10501 ctccattaaa gaaaaggaaa aaacaaatga caaataaaaa tgcatatgcc cagtcgggtg
    10561 tggatgttga agcgggttat gaagttgttg aacggattaa aaagcacgtg gctcgtacgg
    10621 agcgtgcagg tgtcatggga gctcttggtg gctttggtgg tatgtttgac ctttccaaga
    10681 ctggggttaa agaacccgtc ttgatttcag ggactgacgg tgtcggaacc aagctcatgt
    10741 tggctatcaa gtacgacaag cacgatacca tcgggcagga ctgtgtggcc atgtgtgtca
    10801 acgacatcat tgctgcaggt gcggaacccc tctattttct cgactacgta gcgacaggga
    10861 agaatgagcc agctaagcta gaacaagtgg ttgctggtgt ggcagaaggt tgtgtgcagg
    10921 ctggtgctgc cctcatcggt ggggaaacgg ctgaaatgcc gggcatgtac ggcgaagacg
    10981 actatgactt ggctggtttt gcggtcggtg tggctgaaaa atctcaaatc attgacggtt
    11041 caaaggtggt agagggagat gttcttctcg gacttgcttc aagtgggatt cactcaaatg
    11101 gttactcttt ggttcgtcgt gtctttgcgg attacacagg tgaggaagtc ctaccagaat
    11161 tggaaggcaa gaaacttaaa gaagttctac ttgagccgac tcgtatctat gtcaaggctg
    11221 tcttgtcgct catcaaagaa gagttggtca acggcattgc ccacatcaca ggtggtggct
    11281 ttatcgaaaa tgtccctcgt atgtttgcag atgacctagc tgctgaaatt gatgaaagca
    11341 aagttccagt gcttccaatt ttcaaagccc ttgaaaaata cggtcagatt aaacacgaag
    11401 aaatgtttga aatcttcaat atgggtgtgg gactcatgtt ggcggtcagc cctgaaaatg
    11461 tagagcgtgt aaaagaattg ttggatgaag cagtctatga aattggtcgc atcgtcaaga
    11521 aagaaaacga aagtgtcatt atcaaatgaa aaaaatagcg gtttttgcct ctggtaatgg
    11581 ctcaaatttt caggtgattg ccgaagaatt tccagtggag tttgtctttt cagaccatcg
    11641 tgatgcctat gtgcttgagc gtgcaaagca gctcggcgtt ctgtcctatg cttttgaact
    11701 caaggagttt gagagcaagg cagactacga agcagccctt gtcgaactct tggaagaaca
    11761 ccagattgac ttggtttgcc tagcaggcta catgaaaatc gttggaccaa ccttattgtc
    11821 ggcttatgaa ggtcggattg tcaacattca tccagcctac ttgccagaat ttccaggagc
    11881 tcatgggatt gaggatgctt ggaatgctgg cgtgggtcag tctggtgtga ccattcactg
    11941 ggtggattcg ggtgtggata caggccaggt catcaaacag gttcgtgtgc cacgactagc
    12001 tgatgatacc attgacagat ttgaagctcg catccatgaa gcagagtaca ggttgtatcc
    12061 ggaagtagtg aaggctctat ttacagattg actttttgat gattcatatg atatctttga
    12121 ttttaaattg gagtcagtgt ttgttgaaga cggcttcaaa cggaggtatt tgtaatgtta
    12181 gaatctaaaa aaacaactcg atatgtattt tatgtctatc tgatgttatt aacttgggga
    12241 atcttattta agtttgaaac aaatcctgaa tttatagcat ttttcttagc tccaaggtat
    12301 atcaattgga ttccattttc agaaccacta atagtcgatg gaaaaattgt ttttgctgaa
    12361 atgttattta atctgatttc ctttattcca ttaggtgttt gtttcccttt gataaaaact
    12421 aatttatcta gtttaagaat agtcgggaca ggtttcttga ttagtttatt gtttgagtgc
    12481 ttacagtata ttttagcaat aggtataaca gatataacgg atttgacttt aaatacgcta
    12541 ggtgtctgtg taggcttact gatttatcaa atttttataa gagtgttcaa atcacagact
    12601 agaaaatgga tcaatatctt aggtatgctt agccttggtt ttgcttatct tgttttactg
    12661 ttactgcatt taattggtgt ttaactaatg attgaaaagg agaatataat gactaaacgc
    12721 gtcttaatca gcgtctcaga caaagcgggc attgttgaat ttgcccaaga actcaaaaaa
    12781 cttggttggg agattatctc aacaggtgga actaaggttg cccttgataa tgctggggtg
    12841 gataccattg ctatcgatga tgtgactggt ttcccagaaa tgatggacgg tcgtgtgaag
    12901 accctccacc caaatatcca cggagggctt ctcgctcgtc gtgacttgga tagccacttg
    12961 gaagcggcta aggacaacaa gattgagctc attgaccttg tggtggtcaa cctttaccca
    13021 tttaaggaaa ctatccttaa accagatgtg acttatgctg atgcagttga aaatatcgat
    13081 attggtgggc catctatgct tcgttcagca gcgaaaaatc atgccagtgt tacagttgtg
    13141 gtagatcctg ctgactacgc tgtggttttg gatgaattgg cagcaaacgg cgaaacctct
    13201 tatgaaactc gccaacgttt agcagccaaa gtatttcgtc acacagcggc ttatgacgcc
    13261 ttgattgcag aatacttcac agctcaagtg ggtgaaagca agcctgaaaa actcactttg
    13321 acttatgacc tcaagcaacc aatgcgttac ggtgagaatc ctcaacaaga cgcggacttt
    13381 taccagaaag ctttgcctac agactactcc attgcttcag ccaaacagct caacgggaaa
    13441 gaattgtcat ttaataatat ccgtgatgca gatgctgcta tccgtatcat ccgtgacttc
    13501 aaagatagtc caaccgttgt ggctctcaaa cacatgaatc catgtggaat tggtcaagct
    13561 gatgacatcg agactgcttg ggactacgct tatgagtctg acccagtgtc tatctttggt
    13621 gggattgtcg tcctcaaccg tgaggtggat gctgcgacag ctgagaagat gcacggcgtt
    13681 ttcctcgaaa tcatcattgc accaagctat acggatgaag cgctagccat tttgatcaaa
    13741 aagaaaaact tgcgtatcct tgccttgcca tttaatgctc aagaggctag cgaagtggaa
    13801 gcagaataca caggtgtagt cggtggactt ctcgtgcaaa atcaagacgt ggtcaaggaa
    13861 agcccagctg actggcaagt ggtgactaaa cgtcagccaa ctgagacaga agcgactgct
    13921 cttgagttcg cttggaaggc tatcaagtac gtcaaatcaa atggtattat cgtgaccaac
    13981 gaccacatga cacttggtgt tggtccaggt caaaccaacc gtgtggcttc tgttcgcctt
    14041 gccattgacc aagccaaaga tcgtctggac ggggcggtcc ttgcttcaga tgccttcttc
    14101 ccatttgcgg ataacgtgga agaaatcgcc aaagcaggaa ttaaggccat catccagccc
    14161 ggtggctctg tccgtgacca agaatccatc gaagcagcgg ataaatacgg cttgactatg
    14221 gtctttacag gtgtgagaca ttttagacat taagaagata aaagggaaga aaacagtttc
    14281 tttccttttt tggcttaaaa tgctaactga aacaagatta aaacgaactt ttttgatata
    14341 atgttggtaa ataattcgca aaagaggttg aggaatgaaa ctgcttgttg tcggttctgg
    14401 tggtcgtgag catgcgattg ctaaaaagtt acttgaatca aaagacgtgg aaaaagtctt
    14461 tgtagctcct gggaatgatg ggatgactct ggatggtttg gaattggtaa atatctctat
    14521 ttccgaacat tctaaattga ttgacttcgc aaagaccaat gatgttgctt ggacctttat
    14581 cggtccagat gatgcccttg ctgctggtat cgtggatgat tttaaccaag ctgggcttaa
    14641 ggcctttggt ccgactaggg ctgcagcgga gctggagtgg tccaaggatt ttgccaagga
    14701 aatcatggtc aaatatggtg tttcgacagc agcctatggc acattttcag atttcgagga
    14761 agcaaaggcc tatatcgaaa agcatggtgc gcctatcgta gtcaaggcgg atggcttggc
    14821 gcttgggaag ggtgtcgtcg tttctgagac ggttgagcaa gcggtcgaag ccgctcatga
    14881 gatgcttttg gacaataaat ttggtgactc aggtgcgcgc gtggttattg aggaattctt
    14941 tgaaggagag gaattttcac tctttgcctt tgtcaatggt gataagttct acatcatgcc
    15001 aacggctcag gaccacaaac gtgcctatga tggcgacaaa gggcctaaca cgggtggtat
    15061 gggtgcctat gcgccagttc cacacttacc acagagtgta gttgatacag cggttgacac
    15121 cattgtcaag ccagttctag aagggatgat taaagaaggt cgcccttatc tgggagttct
    15181 ttacgcaggg cttatcctga cagctgatgg accgaaagtc attgagttca acgctcggtt
    15241 cggagatcca gaaactcaga ttatcttgcc tcgcttgacc tctgactttg ctcaaaatat
    15301 cacagatatc ctggatagca aggagccaaa tatcatgtgg acggacaagg gtgtgactct
    15361 gggtgtggtt gtcgcatcca agggctaccc gctagactat gaaaggggcg ttgagttgcc
    15421 agccaagaca gaaggcgatg tcatcaccta ctatgcaggg gctaagtttg cggaaaatag
    15481 cagagcactg ctctcaaacg gcggacgagt ttatatgctc gttaccacag cagataccgt
    15541 caaagaagcc caagccagca tctaccaaga actataccaa caaaaaatag aaggactctt
    15601 ctaccgaaca gatatcggaa gcaaggcaat taagtaaaga tataagaata acgcgccgta
    15661 gtcgccaaac acgataatgg tcgtcgtggt gaaaagacca gaacagtgaa tgttctgatc
    15721 agggggaaac ttggagaccg taggctcaaa gtttaggaat gaaaccgaag gtttgcttac
    15781 gcctccatca cctaagacca ttatcaaaaa gaaaaataaa aattcacaaa atacgttaat
    15841 gatcgtatgg tttgcgagcg ttagcgagct aatatagaac aatcaccgcc gttgtgaaag
    15901 aacgattgga tgataatcca atcgttcagg gaaattggaa gaccttgggt ttccaattta
    15961 ggcatgagac acctttggtg gctgctgccg tccctcacaa gctaaggtga ttgttgaaaa
    16021 agaggaaaaa ggagaagaaa tgaaaccagt aatttccatc atcatgggct caaaatccga
    16081 ctgggcaacc atgcaaaaaa cagcagaagt cctagaccgc ttcggtgtag cctacgaaaa
    16141 gaaagttgtt tccgcacacc gtacaccaga cctcatgttc aaacatgcag aagaagcccg
    16201 tagtcgtggc atcaagatca tcatcgcagg tgctggtggc gcagcgcatt tgccaggcat
    16261 ggtagctgcc aaaacaaccc ttccagtcat tggtgtgcca gtcaagtctc gtgctcttag
    16321 tggagtggat tcactctatt ctatcgttca gatgccgggt ggggtgcctg ttgcgaccat
    16381 ggctatcggt gaagctggag cgactaacgc agctctcttt gccctccgtc tcctctctgt
    16441 agaagataag tccattgcgg atgcacttgc caactttgct gaagaacaag gaaaaatcgc
    16501 agaggagtcg tcaaatgagc tcatctaaaa caatcggaat tatcggtggc ggtcaactgg
    16561 gtcagatgat ggccatttct gctatctaca tgggccacaa ggttatcgcg ctggatcctg
    16621 cggcggattg cccgacctct cgcgtggcgg aaatcattgt ggcaccttat aacgatgtgg
    16681 acgccctccg tcagttggca gaccgttgcg atgtcctcac ttatgagttt gaaaatgtcg
    16741 acgctgacgg tttggatgcc gttatcaagg atggacaact ccctcaagga acagatctgc
    16801 tccgcatttc gcaaaatcgt atttttgaaa aggacttttt gtcaaacaag gctcaagtca
    16861 ctgtggcacc ctacaaggtc gtgacttcta gcctagactt ggcagatatc gacttgtcga
    16921 aaaactatgt cctcaagact gcgactggtg gctacgatgg tcatggacaa aaggttattc
    16981 gttcagaagc agacttggaa gcagcctatg cgctagcaga ctcagcagac tgcgtcttgg
    17041 aagaatttgt caactttgac cttgagattt ctgtcatcgt gtcaggaaat ggcaaggagg
    17101 tgacgttttt cccagttcag gaaaatatcc accgcaacaa tatcctgtct aagaccatcg
    17161 taccagcccg catttctgaa agtctagtag acaaggctaa agctatggca gtgcgaatcg
    17221 cagaacaact caacttgtct ggaactctct gtgtggaaat gtttgcgact gatgatgacg
    17281 ttattgtcaa tgaaatcgcc ccacgaccac ataactctgg gcactattct attgaagcct
    17341 gtgatttctc tcagtttgac acccatattc tcggtgttct cggagcacca ttaccagtca
    17401 tcaaactcca tgcgccagcc gttatgctta atgtcctcgg tcagcatgtc gaggctgctg
    17461 agcaatatgt gacagaaaat tcaagcgccc acctccacat gtatggtaaa atagaagcga
    17521 agcacaaccg caagatggga catgtgacct tgtttagtga tgtaccggat agtgtggatg
    17581 agcttgggga agggattgat ttttaggaca agtctatgat acaaattatc gttaatacat
    17641 ttattgaaaa ggataagact ggagcagttg ttgaagtgtt gtatgccagt gctgaccaag
    17701 ataaggtaca agctaaatat gaagaactag ctgcacaata ccccgaaaat tatttagcta
    17761 tctatgatgt accgctggat acggatttga atacactaga tcattacccg tctgtgttta
    17821 ttgaaaaaga ggagtttgag tagaaatctt ggtttaccta gatagcttat tcccaacagc
    17881 ttaagaagaa aggaaaaatt aacacatgat caaccgttac tctcgccctg agatggcgaa
    17941 tatttggagt gaagaaaata aataccgtgc ttggcttgag gtggaaatcc tctctgacga
    18001 ggcatgggct gagttggggg aaatccctaa ggaagatgtg gctttgattc gcaagaaggc
    18061 ggactttgac atcgaccgta ttttggaaat tgagcaggag acgcgccacg atgtggtggc
    18121 tttcacgcgt gcggtttctg agactcttgg tgaagagcgc aagtgggttc actatgggtt
    18181 aacttctacc gacgtggtgg atactgctta tggttacctc tacaagcagg ccaacgacat
    18241 catccgtcgt gaccttgaaa acttcactaa tatcatcgct gacaaggcca aggagcacaa
    18301 gttcaccatc atgatggggc gtactcatgg tgtgcacgct gagccgacaa cctttggtct
    18361 taaattggca acttggtaca gcgaaatgaa acgcaatatc gagcgtttcg agcatgcagc
    18421 tgctggtgta gaagctggta agatttctgg tgcggttggg aactttgcca atatcccacc
    18481 atttgtagag gagtatgtct gcgataaact tggcatccgt gcccaagaaa tctctacaca
    18541 agtccttcct cgtgaccttc acgctgagta ctttgcggtt cttgccagca ttgcgacttc
    18601 aatcgaacgt atggcgactg agattcgtgg tctacaaaaa tctgagcaac gcgaagtaga
    18661 agagttcttt gctaaagggc aaaaagggtc ttcagcaatg cctcacaaac gcaacccaat
    18721 cggttctgaa aatatgactg gtctggcgcg tgtcattcgt ggtcacatga ttacggctta
    18781 tgaaaacgtc gctctctggc acgaacgcga tatttctcac tcatcagctg agcgtatcat
    18841 tacaccagat acgaccattt tgattgacta catgctcaac cgttttggaa atatcgtcaa
    18901 gaacttgaca gtcttcccag aaaatatgat ccgaaacatg aactcgactt ttggtcttat
    18961 ctttagccaa cgggctatgt tgacattgat tgaaaaaggc atgacccgtg agcaagccta
    19021 tgacttggtg caaccaaaaa cagcctactc ttgggacaac caagtagact ttaaaccact
    19081 tcttgaggca gattcagaag taacatcacg tctcactcaa gaagaaatcg atgaaatctt
    19141 caacccagtt tattacacca aacgagtgga tgatatcttt gaacgtcttg gactaggtga
    19201 ttaattaaaa aataaacagc gagattgaag ctcgctgttt attttttatc gaaaagactt
    19261 agtcttcttt tcttttagtg agtccatagg ctgctagtgt ggacatgagt cctgcgacta
    19321 ctagtcctgc agaatcgtga gttcctgttt caggaagttt tttctctgtt accacaggag
    19381 ctggatcttg aggaagagct ttgctttcct cagcaggagc agttgatgga gctggttggc
    19441 ttgggatttc tagttttggt ttttcttcag caatagcggc ttgtccgttt tcatcgccta
    19501 catgtgttac catagttccg acttcgacta tttgagtaac ggcttcctgt gctacgacac
    19561 tatttacaag tgttttcact tccttaccat cggcagaagt gctcacagag tagaagttgc
    19621 tacgatgtcc attgacgccc ttagtaatga cttgtgtttt tcctttgagt aagagtggat
    19681 tttcacgagt cactgtggta aatggaattt cttctttttg gatatccagt ctaggtttta
    19741 cctcagtagt tggtgcaaga ccactttcat cacccttgtg agttacagga gcgccaactt
    19801 caaccacttg gtttataact tctttggtta cctggctatc aaggactgtt tctgttgttt
    19861 ttccattttc agtgagtaca gagatgtaat gagttcgttc acctttgact cctgctgtga
    19921 taatattttc ctgaccagct gggaggttag gattttcttt cttgataact tcaaatggaa
    19981 tttcttcagt tcttgtgatg agttctggtc tggtttcaac attggcagcc acttcatttt
    20041 catccaggct tcctgaatga gttgcagctg gtttgaggcc ttgaagagcg gcttttaggt
    20101 tggctacaag tgtgtcaagc tcagcttgtt tattacggtt gaggttgtaa tttagagctg
    20161 ttttagctgc gtcaagggcc tcaagacttt ctttactata tccttctaag tttgtaggaa
    20221 ttttagctaa ttcttcgcgg agagcattat aattagcacg gaagtagtct ttgttgtggt
    20281 ctgcaaaggc agtcatgagt tcaaagattt cctcttcctt gtattcagcg cttggtctat
    20341 ctgcccagat tgaaagcata cttccgactg ttggaagatc tacttcagga tatttggtag
    20401 aagctagttg attgaatgga actttaccag aattttcaac tgcttttgaa agagggtaag
    20461 cttcatcttg tttgtgattg cctataacat aataccagtc accgttggta ttcaagaatt
    20521 tatagccttt gcttgctagg tattgaggtg atgcgaggtt atatccccac cagcctttag
    20581 accagtaaga aatcaagaca tctttgtcaa actgaacatc gtccttgtct tcatagtaga
    20641 agccatcgtt gaaggccatt ggttgaagcc ctctttcttt ggccatagct gcgagggtgt
    20701 tggcatattc ggcaaatttg ccatagagtt gataccactt gaggtagtac cagccttggg
    20761 cactagtcgc atcgttggcg tattcgtcag taccaaagtt gaaaatcttt gttttacctg
    20821 caaagaagtc catgtattta ccgatgaggg cttttacaaa gttcatcgct tcttcgtttt
    20881 tcaagtccat agttgttttt gaaactttat caaagtgggc ttgaggattt ttaataccta
    20941 atttttccat ggcaaccagc atagcatcca tgtgacctgg actgttaata gctgggatga
    21001 gaccaatgtc cttagattta gcgtattcaa ttagctctgt cacttctgcc tgtgttagtg
    21061 cagtaccgtt tggatcgtcg tagtaagctt tagttccttc gataatagct tttttaacgt
    21121 catcactagc ataggttttt ccgttggcag taatggtcat atcattgagt agaaagcgaa
    21181 gtccgtcatt tcctagaagg agatggacat cagaatatcc gagctcactg gccttgtcta
    21241 cgatgcgttt gagctggtcc agagtaaagt atttgcgtcc agcatcgatt gagattacct
    21301 tgtttttggc aagtttttca acctcacgtt tagcttcttc ttctttttga gcttcaggcg
    21361 tgagggtcaa gttgttgaca gtttcttgaa gtttagcaat ggcttgttca atagtatctt
    21421 gttgggcacg gctaaggttg ctatcgagag agcgaatagc tttttcagct tcttttacgg
    21481 ccgcgacgct ttctgcagta taacggttca ggtcttttgg tacctcgtta agtgcttgct
    21541 ctgcagattc ataatcagct gcgaagtatt cagcgttggc atttgcaaaa tgacgcatga
    21601 gtttgaagag gtgtgatggt gaataacgtg cagatggagt gtcagcccaa gcagctacca
    21661 taccaccgat gattgggata tcagctcctt ctgtttttgg tacagaagtg attggtgtgt
    21721 ttttaatacc attgagcccc tgatcgagat tgtaccagcc ttggccatca gcgtttcgtc
    21781 caagaacgta gtaccaagca tcattggtat taaggatttg gtgacctttt tcagctagta
    21841 gtttagaaga agcgacatcg tagcctcccc aaccaccagt ccacatagaa acgatgatgt
    21901 ctttgtcaaa actaccaaag cttgtgtcgc tattgtagta gataccgtcg ttaaaggcca
    21961 ttggtttgag accgtgcgat tttacaatac gagcgaggtc attggcgtag gcaataaatt
    22021 tttcatagcc ttttacaggg tagccttcgt ttggatagta tttatcagct tgaagcacac
    22081 tccaaccttt agcatctgtc gcatcattgg catattcatc aagtccgatg ttgaagattt
    22141 cagtcttttt cgcgaaataa gcagcatact tgtcgataag ggcttttgta aaagcgacag
    22201 cttgttcgtt gtcaagatcg acagtacggg ctgatttctt cccaaaatag ctaaagttag
    22261 ggttttggat tcccaattct ttcatggcat tgagaatcgc atccatgtgt ccaggactat
    22321 ttactgtcgg aatgagaccg atacctttat ctttggcata gttaatcaga tctgtcattt
    22381 gactttcttt taagtgattg ccgtttggat cgttgtaata atcatttgta cctttttcaa
    22441 tggcgcgttt gacatcgtca ctggcatagg tcttgccgtt agctgtgatg ctcatatcgt
    22501 ccaacatgaa acggagtcca tcatttccga ctaataggtg taaatcagtg tagccataat
    22561 gtttcgcttt atcgatgatt tccttgagct gttctggtga gaaatattta cgtccagcat
    22621 caatggaaac aattttcttt ttcgctagtt tttcatttac agttgtagca cgttcctttc
    22681 ctgcctctgt ttccagtttg tcagcctctg ctttcgcttc ttctttttta gggctagctt
    22741 cttctgcctt tttattagca gtttcttttt cagcagaagt tggagttacc acttctgctt
    22801 tatcactagg agttgaacta acttcctctt gtggtttttc ttctgttttt ggaagactag
    22861 ctaccttatc agtagctgga gtttctgttt ctacagtttt tggagcttct ggttgaagca
    22921 ctgctttagg tgtttcctca gtccgatttt cggatgattg aggggaatca gaaaccgtat
    22981 ggatggtcgg ttggttttct gtagtagtag gagtaactcc atcggctgca acagtctgtg
    23041 cttggaaggc aaatccaatt agaacagaag ctgctcctac agcgtattta cgaatagaaa
    23101 aacgctgttg tttttcatgt ttcattgcaa aacctcctga ttgcattgtt atattgatag
    23161 cgattatata aatcaacgcc tttattttat ttcttatatt aacgagagtc aagaggagat
    23221 gacaaaaaac tataataagt ataaaaaaat ataaaattta aacttaagat ttcagattgg
    23281 tcggaaaaaa tacgtatata tatctagtat aatttttggt tctatttcta taaaatattc
    23341 cacaaattat agaattttcc aaaaataggt aagcgctacc tttttggtgt agtataataa
    23401 gcatagaaaa agcccaagcg attagctcag gttttcttct tagtgatcac ggtcacatga
    23461 gataaattta atcttgtagt aatcagatcg tttgtaagtt tcactgtatt ctaaaacttg
    23521 gccagttgat tcgagtttgg tgattttagt ttgtaggaca gtagggaatt gttcatcgac
    23581 tccgaggact gaagctgcat gttctggagt tggaaagact atttcgttga tttcttcaaa
    23641 gtgttcatca ttcatgtgaa tgtggtagtc taacttgaaa cgattataga tagaactata
    23701 gtattcaagg tttggataat ttgcgttgat atattgttct gggatgtagg atgtatggta
    23761 gatataaacg acaccgtttg attcgcggat acgttcaatc ttgtagtaga attgatcgcc
    23821 gcgtagaccc aatttttcca agtaaacaag cttgtttccg cgttcaattg aaagaacagt
    23881 taccttatca tctttagcat tgaagagttc aatatctgaa aactctacaa gcttgtgttt
    23941 gcgtgcacgt gaaacgaagg ttccttttcc ttgttggcgg acaatatagc catctttggc
    24001 aaggtcgttt aaggcgcgaa caactgtgat agagctgaca tcgtacattg aaatgagttc
    24061 tgcttcagtg taaaatttat ctccactgct aaactgccca gagatgattt tattttttaa
    24121 ttcgtctttt atgtattgat atttgggaat tgccatattt ttacctctat tttccttctt
    24181 ccatagaaaa ttttaccata aaagcgaaaa aaatagtagt cttttgaata aaaaattaga
    24241 ataatagttt gaaaaattaa gcgatatagg gattgctcat attttatcaa tgcattctat
    24301 acaaaattat tttaggtcct atattccgaa tttaaagagc gtttgaaatg ggtctaaaaa
    24361 tgtttgaaac taattgaatg tgtgtataat agtaaaaatg cagtaaatat cccgacaatt
    24421 tctattgaca attcaaacag attggtttat aattaatata acaacaaatg aaagcgcaaa
    24481 ctttcgcggt cggaaggtag ttttatgaca cgatttgaga tacgagatga tttctatctc
    24541 gatggaaaat catttaagat tttatctggt gccattcatt attttagggt tcctccagag
    24601 gattggtatc attcgctcta taacttgaag gctcttggtt ttaatacggt agagacttat
    24661 gttgcttgga atttacacga gcctcgtgaa ggtgagtttc attttgaagg tgatctggat
    24721 ttagagaaat ttctccaaat agcgcaggat ttgggtctct acgcaattgt gcgtccgtct
    24781 ccatttatct gtgcggaatg ggaattcggt ggcttaccag cttggctctt gaccaagaac
    24841 atgcgaattc gctcatccga cccagcatat atcgaggcag ttggtcgcta ctatgatcag
    24901 ttattgccaa gactggtgcc tcgtttgttg gacaatggtg gcaatattct catgatgcag
    24961 gttgaaaatg agtatggttc ttacggagaa gataaggctt acctgagagc gattcgacag
    25021 ctaatggaag agtgtggcgt aacctgtccc ctctttacat cagatggtcc atggcgagct
    25081 actctgaaag ctggaacctt aattgaagag gacctctttg taacaggaaa ctttggttct
    25141 aaggcacctt acaacttttc gcagatgcag gaattctttg atgaacatgg taagaaatgg
    25201 ccactcatgt gtatggagtt ctgggatggt tggttcaatc gctggaaaga accgattatc
    25261 acacgggatc ctaaggaatt ggcagatgca gttcgagagg ttttggaaca aggctctatc
    25321 aatctttaca tgttccacgg tggtacaaac tttggtttca tgaatggttg ctcagctcga
    25381 ggaactttgg acctgccaca agttacatct tatgattacg atgcccttct ggatgaagaa
    25441 ggaaatccaa ctgctaaata tcttgcagtc aagaagatga tggcaacaca tttttcagag
    25501 tatccgcagt tggaaccact ctacaaagag agtatggagt tggatgctat tccactagtt
    25561 gaaaaagttt ctttgtttga aaccttagat agcttgtcaa gtcctgtaga aagtctctat
    25621 cctcaaaaga tggaggagct gggacaaagt tatggctacc tactttatcg aacagaaaca
    25681 aactgggatg cagaagaaga aagacttcgt atcattgatg gtcgagatag ggcccagctg
    25741 tatgtcgatg gtcagtgggt taaaactcaa tatcagacag agattgggga agatattttt
    25801 tatcaaggta aaaagaaagg gctatctagg ttagatatct tgatagaaaa tatggggcgt
    25861 gtcaactatg ggcataagtt cttagcggat acgcaacgta agggaattcg gacaggggtc
    25921 tgtaaggatc tgcatttctt actaaactgg aaacactatc cactcccact agacaatcct
    25981 gagaaaattg atttttcaaa aggatggact caaggacaac cagcctttta cgcttatgac
    26041 tttacagtcg aagagccaaa agatacttac ctagacttgt ctgagtttgg taagggggtt
    26101 gcctttgtca atgggcagaa tctaggacgt ttttggaacg ttggcccaac tctctcactt
    26161 tatatccctc atagctatct caaggaaggt gccaaccgca tcattatctt tgaaacagaa
    26221 ggtcaatata aagaagagat tcatttaact cgtaaaccta cactaaaaca tataaagggg
    26281 gaaaacttat gacaattgta ggatgccgta ttgatggacg tttgatccac ggacaagtag
    26341 ccaatctttg ggctggaaaa ctaaatgttt cacgcattat ggttgtagac gacgaagttg
    26401 tcaacaacga tattgaaaag agtggtttga aacttgcgac accaccaggt gtgaaattga
    26461 gtattttgcc aattgagaaa gctgcagcca atattcttgc tggcaaatac gatagccaac
    26521 gtctctttat cgtggctcgt aaaccagacc gcttccttgg tttggtagaa gcaggtgtac
    26581 cacttgaaac ccttaatgtt gggaatatgt ctcaaacacc agaaactcgt tctattacac
    26641 gttctatcaa cgtagtagac aaggatgtgg aagacttcca caaactggca gaaaaaggtg
    26701 ttaaacttac tgctcagatg gttccaaatg atccaatttc agactttttg agcttattaa
    26761 aataggaaaa aaatttttag gaggtcattg ttatgataca atggtggcaa attttacttc
    26821 tcactttgta ctcagcttat caaatctgtg atgagttgac gatcgtttca tctgcaggtt
    26881 ctcctgtatt tgctggtttc attactggtt taatcatggg agatgtgact actggtttac
    26941 ttatcggtgg taacttgcaa ctgttcgttc ttggggttgg taccttcggt ggtgcttctc
    27001 gtatcgacgc aacttctggt gcggttcttg cgacagcctt ctctgtttca caaggaattg
    27061 atgcaccgct tgccattact acaatcgctg taccagtagc agctctcttg acttacttcg
    27121 acgttcttgg tcgtatgact actaccttct tcgctcaccg tgtggatgct gcaatcgaac
    27181 gctttgacta taaaggtatt gaacgcaact acttgcttgg tgcgattccg tgggctctat
    27241 ctcgtgccct tccagtcttc tttgcccttg cttttggtgg tgcctttgta caatcagtag
    27301 tagacttcgt tgaagcctac aaatgggttg cagatggctt gacactcgca ggacgtatgc
    27361 ttccaggtct tggatttgca attttgcttc gttaccttcc agttaaacgt aaccttcact
    27421 accttgctat gggatttggt ttgacagcta tgttgactgt tctttactca tatgtaacag
    27481 gtcttggtgg cgctgttgct ggtatcgtag gtactcttcc tgctgaagtt gctgaaaaaa
    27541 ttggtttcgt gaacaacttc aaaggtttgt ctatgattgg tatttctatc gtaggtattt
    27601 tccttgcagt gcttcacttc aaaaatagcc aaaaagtagt tgtagcagca ccttctacac
    27661 catcagaaag tggggaaatc gaagatgacg aattctaatt acaaacttac aaaagaagat
    27721 tttaatcaaa tcaacaaacg tagcttgttt actttccaat taggttggaa ctacgaacgt
    27781 atgcaagctt ctggttacct ttacatgatc ttgcctcagt tgcgtaaaat gtatggtgat
    27841 ggaactcctg aattgaaaga aatgatgaaa gttcatactc aattcttcaa tacttcgcca
    27901 ttcttccata ccattatcgc tggttttgac cttgccatgg aagaaaaaga tggtgtaggt
    27961 tcaaaagacg ccgttaacgg tatcaagaca ggtttgatgg gaccattcgc tcctcttggg
    28021 gatacaatct ttggttcact tgtacctgct atcatggggt cagtcgcagc aactatggct
    28081 atcgctggcc aaccttgggg gatcttcctt tggattgcag ttgcagtagc gtatgacatc
    28141 ttccgttgga aacagttgga atttgcttac aaagaagggg ttaaccttat caacaacatg
    28201 caaagtacct tgacagcttt gattgacgct gcatctgtac ttggtgtctt catgatgggt
    28261 gctcttgtag caacagtgat taactttgaa atttcttaca agttgccaat cggtgaaaag
    28321 atgattgatt tccaagacat cttgaaccaa atcttcccac gtttgcttcc agcaatcttt
    28381 actgccttta tcttctggtt gcttggtaag aaaggtatga actctactaa agctatcggt
    28441 attattatcg tacttgcttt ggctctttct gcccttggtc actttgcact tggaatgtaa
    28501 ttccttatga ctaaatcatt aattttggtg agccatggtc gcttctgtga ggagcttaga
    28561 ggtagcacag aaatgattat gggcccacaa gacaacattt acacagtagc tcttcttcca
    28621 gaagatagcc cagaagaatt tactgctaaa tttgaagctg ttattgaagg attggatgat
    28681 ttcctagttt ttgcggatct tctcggtggg acaccttgta atgtggtgag tcgcttgatc
    28741 atggaaggtc gtgatattga cctttacgca gggatgaatc ttccaatggt gattgaattt
    28801 atcaatgcga gccttacagg cgcagatgcg gactacaaga gccgtgctgc agaaagcatt
    28861 gtgaaagtta atgacctgtt agcgggcttc gatgatgacg aagatgaata atactcttcg
    28921 aaaatctctt caaactacgt caacgtcgcc ttaccgtagg tatatgttac tgacttcgtc
    28981 agtcttatcc ggcaacctca aaacggtgtt ttgagctgac ttcgtcagtc ttatccggca
    29041 acctcaaagc agtgctttga gcagcctgcg gctagtttcc tacagatttt agttggaact
    29101 cgattcaatt catgtgacaa cgtgaaaatc gttagagcat tttatataga atatacatgg
    29161 gaatggagct tactcccatt cctatattta atagaaaaag aggaactcaa tgctacatta
    29221 tacaaaagaa gacttgctcg aattgggtgc agaaatcact acgcgtgaaa tctaccaaca
    29281 gcctgatgta tggagagaag cttttgaatt ttatcaagca aaacgtgaag aaattgcagc
    29341 cttcctacaa gaaatcgctg ataaacatga ctatattaag gttatcttga caggtgctgg
    29401 gacttctgct tatgtgggag acaccttgct accttacttt aaggaagtct atgacgaacg
    29461 caaatggaat ttcaatgcta ttgcgacaac agatatcgtt gccaatccag caacctattt
    29521 gaaaaaagat gtggcaacta tccttgtgtc ttttgctcgt agtgggaact cgcctgaaag
    29581 tgtggcgact gttgatttgg ccaaatcctt ggtggatgag ctttatcaag tgacgattac
    29641 ttgtgcaaca gatggtaaat tggctcttca agctcacggt gatgaccgta atctcttgct
    29701 cttgcaacca gctgtctcta atgatgctgg atttgccatg acttctagct ttacgtctat
    29761 gatgttgaca gctctcttgg tctttgatcc tacagaattt gctgttaagt ctgaacgttt
    29821 tgaagttgta tctagtcttg cccgtaaagt tttagacaag gcagaagatg tcaaagagct
    29881 cgttgattta gactttaacc gtgtcatcta tctaggcgct ggtcctttct ttggacttgc
    29941 tcatgaagct cagctcaaga ttttggaatt aactgctggt caagttgcga ccatgtatga
    30001 aagcccagtt ggcttccgtc acggtccaaa atctcttatc aacgacaata cagttgtttt
    30061 ggtctttggt acaacgacag actacactcg taagtacgac ttggacttgg ttcgtgaagt
    30121 tgctggtgac cagattgctc gtcgtgttgt gcttttgagt gatcaagctt ttggtcttga
    30181 aaatgtcaaa gaagtggccc ttggttgtgg cggtgtcttg aatgatattt accgtgtctt
    30241 cccttacatc gtttatgccc aactctttgc tttattgact tcactcaagg tagaaaataa
    30301 accagataca ccgtctccta caggtacagt aaaccgtgta gtacaaggtg tcataattca
    30361 cgaatatcaa aagtaagaca gtgtttatga attcttgaca agaggatttg taaattatca
    30421 gataaaccat agattgtcag tacgctttct atggtttgtt tgcttgagag aaatagtaaa
    30481 aggagaacag aatgaaagca tacacagagc gtgtatttgg aaatgttgag ggtgaggatg
    30541 tcttggccta tcgatttgag acagacggtg gctaccaact tgaggttatg acttatggtg
    30601 cgactatctt gcgctatgtc gcacctgaca aggctggaaa ttttgccaat gttatcttgg
    30661 gatttgatga ctttgatagt tatgtaggca atagtcccaa gcatggagca agtgtaggtc
    30721 ctgtagcggg tcgtattgca ggtgcgacct ttgagctcaa tggtaagacc tatgaccttg
    30781 aggttaataa tgctagcaac tgtaatcaca gtggttcaac tggttgggat tccagcttgt
    30841 ttgaagttga agaagtaagc gatcatggct tgactctcta cacagagcgt acagatggga
    30901 caggagggtt ccctggaaat ctcaagattt ggatcagtta tcacttggaa gaaactggtg
    30961 cctatgaaat cagctacaag gtaacgaccg atcaggatac gctggtcaat ccaaccaacc
    31021 acagctattt caacttgtct ggtgatttca cgcagacgat tgaccgtcat gtcttccaac
    31081 taaacacaga gggcatttac tcaatcgctc ctgacggtgt tcctgccaaa actccagaag
    31141 ccaaccgtga tgtggtcaaa cacgtctaca atggtacctt gttgaaggat atctttgcag
    31201 aagaagatga gcaaatccag ctggcatcag gtttggatca tccatttgcc cttcctgcag
    31261 gccatgacaa tgctggattc ctttatgacc aaaattcagg tcgcttcctg cttttcaaga
    31321 cagaagctcc ttgctttgtg gtctacacag caaactttgt ggatgaaagt gtcatcatag
    31381 gaggtcagcc aatgctacag cacaatggga ttgctcttga agcgcaagct ttaccagatg
    31441 ccattcacag tgaccttaaa ggccaagtca ttcttaaagc tggtcaaacc ttcaccagta
    31501 agacacgtta tgaacttgtt gtgaaataaa aaaagctggt caaaaagtct ttaaaattaa
    31561 aataacgcat attgtcaggt gatgaaaagt ttgataatat gcgttttatt at
//
LOCUS       DBEJAU010000024        31213 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC323 isolate 683620
            SAMN38261939-rid24807223.denovo.024, whole genome shotgun sequence.
ACCESSION   DBEJAU010000024 DBEJAU010000000
VERSION     DBEJAU010000024.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261939
            Sequence Read Archive: SRR26833919
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 31213)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 31213)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576303.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576303.1
            Genome Coverage       :: 154x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/19/2025 01:05:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,121
            CDSs (total)                      :: 2,078
            Genes (coding)                    :: 1,943
            CDSs (with protein)               :: 1,943
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 36
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 72 of 135
            Pseudo Genes (incomplete)         :: 63 of 135
            Pseudo Genes (internal stop)      :: 51 of 135
            Pseudo Genes (multiple problems)  :: 46 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..31213
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261939-rid24807223.denovo.024"
                     /strain="GPSC323"
                     /isolate="683620"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            83..880
                     /locus_tag="ACL29Z_001116"
     CDS             83..880
                     /locus_tag="ACL29Z_001116"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000254803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0015499 - formate transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0015724 - formate transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="formate/nitrite transporter family protein"
                     /protein_id="HGR0069437.1"
                     /translation="MVSSEFISKIEFACNKKESLYSQSKFKYAIRSMFAGAFLTFSTA
                     AGAVGADLINKIAPGSGRFLFPFVFAWGLAYIVFLNAELVTSNMMFLTAGSFLKKISW
                     RKTAEILLYCTLFNLIGALIAGWGFAHSAAYANLTHDSFISGVVEMKLGRSNELVLLE
                     AILANIFVNIAILSFILVKDGGAKLWLVLSAIYMFVFLTNEHIAANFASFAIVKFSVA
                     ADSIANFGVGNMLRHWGVTFIGNFIGGGLLMGLPYAFLNKNEDTYVD"
     gene            1028..2287
                     /locus_tag="ACL29Z_001117"
                     /pseudo
     CDS             1028..2287
                     /locus_tag="ACL29Z_001117"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018365067.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0016765 - transferase activity,
                     transferring alkyl or aryl (other than methyl) groups
                     [Evidence IEA];
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA];
                     GO_process: GO:0019346 - transsulfuration [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="O-acetylhomoserine
                     aminocarboxypropyltransferase/cysteine synthase family
                     protein"
     gene            2383..3657
                     /locus_tag="ACL29Z_001118"
     CDS             2383..3657
                     /locus_tag="ACL29Z_001118"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001002592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2130 domain-containing protein"
                     /protein_id="HGR0069438.1"
                     /translation="MNEIKCPNCGEVFTVNESQYAELLSQVRTAEFDKELHDRMKQEL
                     ALAEQKAMNEQQTKLAQKDQEIAQLQSQIQNFDTEKELAKKEVEQTSHEALLAKDKEV
                     QLLENQLATLRLEHENQLQKTLSDLEKERDQVKNQLLLQEKENELSLASVKQNYEAQL
                     KAASEQVEFYKNFKAQQSTKAIGESLEQYAESEFNKVRSFAFPNAYFEKDNKVSSRGS
                     KGDFIFRECDENGVEIISIMFEMKNEADGTEKKHKNADFYKELNKDRREKNCEYAVLV
                     TMLEADNDYFNTGIVDVSHEYEKMYVVRPQFFIQLIGLLRNAALNSLKYKQELALVRE
                     QNIDITHFEEDLDAFKLAFAKNYNSASTNFGKAIDEIDKAIKRMEEVKKFLTTSENQL
                     RLANNKLEDVSVKKLTRKNPTMKAKFEALKGE"
     gene            3667..4545
                     /gene="truB"
                     /locus_tag="ACL29Z_001119"
     CDS             3667..4545
                     /gene="truB"
                     /locus_tag="ACL29Z_001119"
                     /EC_number="5.4.99.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006145474.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0009982 - pseudouridine synthase activity
                     [Evidence IEA];
                     GO_process: GO:0001522 - pseudouridine synthesis [Evidence
                     IEA];
                     GO_process: GO:0009451 - RNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(55) synthase TruB"
                     /protein_id="HGR0069439.1"
                     /translation="MNGIINLKKEAGMTSHDAVFKLRKILGTKKIGHGGTLDPDVVGV
                     LPIAVGKATRMVEFMQDEGKIYEGEITLGYSTKTEDASGEVVAETPVLSLLDEKLVDE
                     AIASLTGPITQIPPMYSAVKVNGRKLYEYARAGQEVERPERQVTIYQFERTSPISYDG
                     QLARFTFRVKCSKGTYIRTLSVDLGEKLGYAAHMSHLTRTSAAGLQLEDALALEEIAE
                     KVEAGQLDFLHPLEIGTGDLVKVFLTPEEATEVRFGRFIELDQTDKELAAFEDDKLLA
                     ILEKRGNLYKPRKVFS"
     gene            4786..5088
                     /locus_tag="ACL29Z_001120"
     CDS             4786..5088
                     /locus_tag="ACL29Z_001120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000985087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin immunity protein"
                     /protein_id="HGR0069440.1"
                     /translation="MMRNEFRERVEQLLQQKEINENSELSHLFRLAIQNLDRNEKYQS
                     VMANLSQGLSLYLMTHHYQAPKSVIDFGLWIAKAPSQERGRLAFLQMLAQTLQGFR"
     gene            5196..5834
                     /gene="udk"
                     /locus_tag="ACL29Z_001121"
     CDS             5196..5834
                     /gene="udk"
                     /locus_tag="ACL29Z_001121"
                     /EC_number="2.7.1.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001181378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004849 - uridine kinase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="uridine kinase"
                     /protein_id="HGR0069441.1"
                     /translation="MQNRPIIIGVTGGSGGGKTSVSRAILSHFPDEKISMIEHDSYYK
                     DQSHLTFEERVKTNYDHPFAFDTDLMIEQIKELLAGRPVDIPTYDYTEHTRSSKTYRQ
                     EPQDVFIVEGILVLEDKRLRDLMDIKIFVDTDDDVRIIRRIKRDMEERGRSLDSVINQ
                     YLGVVKPMYHQFIESTKRYADIVIPEGVSNTVAIDLLTTKIAKILEEARNSK"
     gene            5962..7302
                     /gene="xseA"
                     /locus_tag="ACL29Z_001122"
     CDS             5962..7302
                     /gene="xseA"
                     /locus_tag="ACL29Z_001122"
                     /EC_number="3.1.11.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012000165.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009318 - exodeoxyribonuclease VII
                     complex [Evidence IEA];
                     GO_function: GO:0008855 - exodeoxyribonuclease VII
                     activity [Evidence IEA];
                     GO_process: GO:0006308 - DNA catabolic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease VII large subunit"
                     /protein_id="HGR0069442.1"
                     /translation="MEKYLSVTTLTKYLKMKFDKDPYLERVYLTGQVSNFRKRPTHQY
                     FSLKDDHAVIQATIWSGIYQKLGFDLEEGMKINVIGRVQVYEPSGSYSIIIEKAEPDG
                     VGALAIQFEQLKKKLTEEGLFQERFKQALPQFSKRIGVVTSRSGAVIRDIITTVSRRF
                     PGVDILLYPTKVQGEGAAEEIARNIARANQRDDLDLLIIGRGGGSIEDLWAFNEEIVV
                     RAIFESRLPVISSVGHETDVTLADFVADRRAATPTAAAELATPVTKLDVLAHLQNQEK
                     RMVTAVRNVLSKKQEALKKCSQSVIFRQPERLYDGYLQRLDQLQLRLKQSLRTRISDN
                     KQLVQARTHQLVQLSPVTKIQRYQDRLGQLDKLLGSQMALVYDAKVAEAKRLSEALLM
                     LDTSRIVARGYAIVKKEESVVDSVESLKKKDQVTLLMRDGQVELEVKDVKTKEI"
     gene            7280..7492
                     /locus_tag="ACL29Z_001123"
     CDS             7280..7492
                     /locus_tag="ACL29Z_001123"
                     /EC_number="3.1.11.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease VII small subunit"
                     /protein_id="HGR0069443.1"
                     /translation="MSKQKKFEENLAELETIVQSLENGEIALEDAITAFQKGMVLSKE
                     LQATLDKAEKTLVKVMQEDGTESDFE"
     gene            7489..8364
                     /locus_tag="ACL29Z_001124"
     CDS             7489..8364
                     /locus_tag="ACL29Z_001124"
                     /EC_number="2.5.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000743807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004659 - prenyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0008299 - isoprenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="polyprenyl synthetase family protein"
                     /protein_id="HGR0069444.1"
                     /translation="MKKQEKLALVESALEDFYGDQQFASSLRESVLYSIHAGGKRIRP
                     FLLLEVLEALQVTIKPAHAQVATALEMIHTGSLIHDDLPAMDDDDYRRGRLTNHKKFG
                     EAMAILAGDALFLDSYALIAQADLPSQIKVDLIANLSLASGSLGMVAGQVLDMEGEHQ
                     HLSLEELQTIHANKTGKLLAYPFQAAAIIAELSPEMQVKLKTVGELIGLAFQVRDDVL
                     DVTASFEEIGKTPQKDLQAEKSTYPALLGLEESIAFCNQTLDQANEKLEEIAQQLPFE
                     TESIVSVVESLRING"
     gene            8357..9172
                     /locus_tag="ACL29Z_001125"
     CDS             8357..9172
                     /locus_tag="ACL29Z_001125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001041085.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008168 - methyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0032259 - methylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TlyA family RNA methyltransferase"
                     /protein_id="HGR0069445.1"
                     /translation="MAKERVDVLAYKQGLFETREQAKRGVMAGLVVAVLNGERFDKPG
                     EKIPDDTELKLKGEKLKYVSRGGLKLEKALQVFDLSVDGATTIDIGASTGGFTDVMLQ
                     NSAKLVFAVDVGTNQLAWKLRQDPRVVSMEQFNFRYAEKTDFEQEPSFASIDVSFISL
                     SLILPALHRVLADQGQVVALVKPQFEAGREQIGKNGIIRDAKVHQNVLESVTAMAVEV
                     GFSVLGLDFSPIQGGHGNIEFLAYLKKEKSASNQILAEIKEAVERAHSQFKNE"
     gene            9165..9596
                     /locus_tag="ACL29Z_001126"
     CDS             9165..9596
                     /locus_tag="ACL29Z_001126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001034407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine repressor"
                     /protein_id="HGR0069446.1"
                     /translation="MNKKERLEKIRRLVTDYQIGTQEEIVEHLKEAGITATQATVSRD
                     IKELGIVKIPLRDNTYVYELPKSIVKSLQLAEDNIESAELMDKMINLQVIPGNTAFVK
                     AQLIETFADKIFSCLTDDSSILVIARSGSLAEEIFEQVKNW"
     gene            9603..11270
                     /gene="recN"
                     /locus_tag="ACL29Z_001127"
     CDS             9603..11270
                     /gene="recN"
                     /locus_tag="ACL29Z_001127"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RecN"
                     /protein_id="HGR0069447.1"
                     /translation="MLLEISIKNFAIIEAISLNFEKGMTVLTGETGAGKSIIIDAMNM
                     MLGARATTDVIRHGAPKAEIEGLFSVENSRLLQEIFDEQGLELGDEIIIRREILQNGR
                     SISRVNGQMVNLSVLRAIGQHLVDIHGQHDHEELMRPQLHIQMLDEFGDAAFWDLKET
                     YQTSFDAYRKMRKQVLEVKKNQQEHKARIEMLEFQMAEIEAANLQAGEDLALNQERDK
                     LLNHKNIADTLTNAYSMLDNEDFSSLANVRSAMNDMESVEEYDPEYREISSSLSETYY
                     VLEDISKRLEAIIEDLDFDGNRLMQVENRLDLLHTITRKYGGTVDDVLLYFAKITEEY
                     NLLTGNNLSSEDMEAELKKLEVNLVNLAGQLASARHNLAQQLEAEIKQELQDLYMEKA
                     QFQVRFSKGKFSREGNKMVEFYISTNPGEDFKPLVKVASGGELSRLMLAIKSAFSRKE
                     GKTSIVFDEVDTGVSGRVAQAIAQKIHKIGQHGQVLAISHLPQVIAIADYQFFIEKIS
                     NDHSTVSTVRLLTVEERVEEVAKMLAGDDVTEAALTQARELLRNREK"
     gene            11272..12000
                     /locus_tag="ACL29Z_001128"
     CDS             11272..12000
                     /locus_tag="ACL29Z_001128"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000133310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HGR0069448.1"
                     /translation="MTDYYVIGDVHGKAGMLEDLLKTWDGQPQLLFLGDLIDRGEDSH
                     RVLEMVKDLVDNQGAICLSGNHEYMFLTWLDDPEESYDHYSRNGGDTTINSILGRPLD
                     APVDGVEDAKRVAAEAADLVEFIRQMPFVVETDKYIFVHAGIDLTLDDWHETTDYKKV
                     WLRKPFHGAENHTGKTIVFGHTPVYGLLQQERGTSELWTTEDGKIGMDGGAVYGGVLH
                     GIVFTDQGMTEHHFIENDGFVAED"
     gene            12079..13902
                     /gene="lepA"
                     /locus_tag="ACL29Z_001129"
     CDS             12079..13902
                     /gene="lepA"
                     /locus_tag="ACL29Z_001129"
                     /EC_number="3.6.5.n1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001047203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="translation elongation factor 4"
                     /protein_id="HGR0069449.1"
                     /translation="MNLEELKKRQEKIRNFSIIAHIDHGKSTLADRILEKTETVSSRE
                     MQAQLLDSMELERERGITIKLNAIELNYTAKDGETYIFHLIDTPGHVDFTYEVSRSLA
                     ACEGAILVVDAAQGIEAQTLANVYLALDNDLEIMPIINKIDLPAADPERVRTEIEDVI
                     GLDASEAVLASAKAGIGIEEILEQIVEKVPAPTGDVTAPLKALIFDSVYDAYRGVILQ
                     VRVMDGVVKPGDKIQLMSNSKTFDVAEVGIFTPKAVGRDFLATGDVGYIAASIKTVQD
                     TRVGDTVTLATNPAAEPLHGYKQMNPMVFAGLYPIESNKYNDLREALEKLQLNDASLQ
                     FEPETSQALGFGFRCGFLGLLHMDVIQERLEREFNIDLIMTAPSVIYKVNLTDGESMD
                     VSNPSEFPDPTKIATIEEPYVKAQIMVPQEFVGAVMELAQRKRGDFVTMDYIDDNRVN
                     VIYQIPLAEIVFDFFDKLKSSTRGYASFDYELSEYRPSKLVKMDILLNGDKVDALSFI
                     VHKDFAYERGKLIVDKLKKIIPRQQFEVPIQAAIGHKIVARTDIKALRKNVLAKCYGG
                     DVSRKRKLLEKQKAGKKRMKSIGSVEVPQEAFLSVLSMDEE"
     gene            complement(13983..14180)
                     /locus_tag="ACL29Z_001130"
     CDS             complement(13983..14180)
                     /locus_tag="ACL29Z_001130"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0069450.1"
                     /translation="MKIKEQTRKLAAGCSKHCFEVVDETDEVSSKHGFEVVDETDEVS
                     NHTYGKATLTWFEEIFEEYKN"
     gene            complement(14222..14452)
                     /locus_tag="ACL29Z_001131"
     CDS             complement(14222..14452)
                     /locus_tag="ACL29Z_001131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000832182.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0069451.1"
                     /translation="MKRVILLAVIQAVVLFFIIGALAYAFKGDFFYNYLAVVFAPIAG
                     VLRFGTAYITEIVLPRKAAEIAEKRKAGKNSK"
     gene            complement(14470..15111)
                     /locus_tag="ACL29Z_001132"
     CDS             complement(14470..15111)
                     /locus_tag="ACL29Z_001132"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004258056.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II CAAX endopeptidase family protein"
                     /protein_id="HGR0069452.1"
                     /translation="MKLLKNLGWILLALLSFLFIYGFIQGLATASLALGASPYAVTLL
                     YVALAVVYVYGIYKWYQKAPVHIEKSGFNRFIWLPVLVWFLSLVVQFFLPDDPSVNQQ
                     IATDLTLSQPLFSFFAVVIFAPLTEEIVFRGMLARYLFPKQDNSKRTLIFLLVSSLLF
                     ALIHFPGDVQQFFVYFSLGFSLGLAYISRKGLVYSISLHALNNLVGFLMILML"
     gene            complement(15123..15857)
                     /locus_tag="ACL29Z_001133"
     CDS             complement(15123..15857)
                     /locus_tag="ACL29Z_001133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3169 family protein"
                     /protein_id="HGR0069453.1"
                     /translation="MKKKRRLLFLMSIVLGGFLGMFVGMFKARVESHEIILDVKALMP
                     WISAICLLIGFISMFLTFNFLKKSRKFHSLYQEEMDDDLNETYYVQMYRNLEFGTIAF
                     NITGVAIPLAIFISLSEVIILHTNPQTFFLSFLLFVVFLVAQKSLFKTIAIVRQFDLE
                     FFATPKDVLNYINSYDEGERQANLEQSFRILFQLHQYILPALYIFLIIISFLTGEIQL
                     LAFLLVGAIHVYINVMQLPMVKRYFK"
     gene            complement(15860..16057)
                     /locus_tag="ACL29Z_001134"
     CDS             complement(15860..16057)
                     /locus_tag="ACL29Z_001134"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001046145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0069454.1"
                     /translation="MNKYKVIYYVVVIALLVSVFLLIGMDLSWFNPYQSDQFVWVYFA
                     LIPVIEWIEKKSKNLASEKGE"
     gene            complement(16057..16263)
                     /locus_tag="ACL29Z_001135"
     CDS             complement(16057..16263)
                     /locus_tag="ACL29Z_001135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001176227.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HGR0069455.1"
                     /translation="MQLKNRLKELRARDGLNQTDLAKLAGVSRQTISLLERDEYTPSI
                     IIALKISQIFNETVESVFRLEEDE"
     gene            complement(16273..16737)
                     /locus_tag="ACL29Z_001136"
     CDS             complement(16273..16737)
                     /locus_tag="ACL29Z_001136"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000566071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0069456.1"
                     /translation="MIDKVVRNLLLTFFFCKMTKIINFLTAILVKKKKMCYNVSKLRE
                     KKKGAMMWVLVFILFIIFFYSNNSKKIKKLENKIKKLERKEKGNAEMSRLLQEMIGKK
                     PIITGVYIGPDNWEVVDVDEEWVKLRRVDNTGKEKFKLQRIEDIQTVEFDGE"
     gene            complement(16842..18131)
                     /gene="hisS"
                     /locus_tag="ACL29Z_001137"
     CDS             complement(16842..18131)
                     /gene="hisS"
                     /locus_tag="ACL29Z_001137"
                     /EC_number="6.1.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004821 - histidine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006427 - histidyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="histidine--tRNA ligase"
                     /protein_id="HGR0069457.1"
                     /translation="MKLQKPKGTQDILPAESAKWQYVEGFAREIFKRYNYAEVRTPIF
                     EHYEVISRSVGDTTDIVTKEMYDFYDKGDRHITLRPEGTAPVVRSYVENKLFAPEVQK
                     PSKFYYMGPMFRYERPQAGRLRQFHQIGVECFGSSNPATDVETIAMAAHFLKEIGIQG
                     VKLHLNTLGNPESRAAYRQALIDYLTPLKETLSKDSQRRLEENPLRVLDSKEKEDKVA
                     VENAPSILDFLDEESQTHFDAVRQMLENLGVDYIIDTNMVRGLDYYNHTIFEFITEIE
                     GNDLTVCAGGRYDGLVAYFGGPETAGFGFGLGVERLLLILEKQGVALPIENALDVYIA
                     VLGDGANVKALELVQALRQQGFKAERDYLNRKLKAQFKSADVFAAKTLITLGESEVES
                     RQVTVKNNQTREEVQVSLETISQNFSEIFEKLGFYTQ"
     gene            complement(18209..19415)
                     /locus_tag="ACL29Z_001138"
                     /pseudo
     CDS             complement(18209..19415)
                     /locus_tag="ACL29Z_001138"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864357.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transporter"
     gene            complement(19606..20457)
                     /gene="rgg"
                     /locus_tag="ACL29Z_001139"
     CDS             complement(19606..20457)
                     /gene="rgg"
                     /locus_tag="ACL29Z_001139"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398326.1"
                     /note="Rgg, as the term is used in Streptococcus
                     pneumoniae, is the lone quorum-sensing system
                     transcriptional regulator related to proteins Rgg1, Rgg2,
                     Rgg3, and Rgg4 of Streptococcus pyogenes; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="quorum-sensing system transcriptional regulator
                     Rgg"
                     /protein_id="HGR0069458.1"
                     /translation="MEQIGKVFRQLRESRNISLRQATGGQFSPSMLSRFETGQSELSV
                     EKFLFALENISASVEEILFLARGFQYDTDSELRKEITDVLEPKNIAPLEDLYRREYQK
                     HAHSHNKQKHILNAIIIKSYMKSIDERVELTAEEGKVLHDYLFSTEIWGIYELNLFSV
                     SSPFLSVSLFTRYVREMVRKSDFLMEMSGNRNLFHTILLNGFLASIECEEFTNAYYFK
                     RVIEEHFYKENETYFRIVYLWAEGLLDSKQGRVKEGQKKMEDAVRIFEMLGCNKSAEY
                     YRKTLDS"
     gene            20581..20922
                     /locus_tag="ACL29Z_001140"
     CDS             20581..20922
                     /locus_tag="ACL29Z_001140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003080443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-sulfur cluster assembly factor"
                     /protein_id="HGR0069459.1"
                     /translation="MRDDIKINDRALALQDQIIEKLEKVFDTDVELDVYNLGLIYEIN
                     LDETGLCKIVMTFTDTACDCAESLPIEIVAGLKQIEGIKDIKVEVTWSPAWKITRISR
                     YGRIALGLPPR"
     gene            20986..21240
                     /locus_tag="ACL29Z_001141"
     CDS             20986..21240
                     /locus_tag="ACL29Z_001141"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0069460.1"
                     /translation="MKIKGQTRKLAASCSKHCFEVMDRTDEVSSKYCFEVVDRTDEVS
                     SKHCFEVADRTDEVSSKHCFEVVDRTDEVSNHTYGKATLT"
     gene            complement(21266..22969)
                     /gene="ilvD"
                     /locus_tag="ACL29Z_001142"
     CDS             complement(21266..22969)
                     /gene="ilvD"
                     /locus_tag="ACL29Z_001142"
                     /EC_number="4.2.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000137341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004160 - dihydroxy-acid dehydratase
                     activity [Evidence IEA];
                     GO_process: GO:0009082 - branched-chain amino acid
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroxy-acid dehydratase"
                     /protein_id="HGR0069461.1"
                     /translation="MTELDKRHRSSIYDSMVKSPNRAMLRATGMTDKDFETPIVGVIS
                     TWAENTPCNIHLHDFGKLAKEGVKSAGAWPVQFGTITVADGIAMGTPGMRFSLTSRDI
                     IADSIEAAMSGHNVDAFVAIGGCDKNMPGSMIAIANMDIPAIFAYGGTIAPGNLDGKD
                     IDLVSVFEGIGKWNHGDMTAEDVKRLECNACPGPGGCGGMYTANTMATAIEVLGMSLP
                     GSSSHPAESADKKEDIEAAGRAVVKMLELGLKPSDILTREAFEDAITVTMALGGSTNA
                     TLHLLAIAHAANVDLSLEDFNTIQERVPHLADLKPSGQYVFQDLYEVGGVPAVMKYLL
                     ANGFLHGDRITCTGKTVAENLADFADLTPGQKVIMPLENPKRADGPLIILNGNLAPDG
                     AVAKVSGVKVRRHVGPAKVFDSEEDAIQAVLTDEIVDGDVVVVRFVGPKGGPGMPEML
                     SLSSMIVGKGQGDKVALLTDGRFSGGTYGLVVGHIAPEAQDGGPIAYLRTGDIVTVDQ
                     DTKEISMAVSEEELEKRKAETTLPPLYSRGVLGKYAHIVSSASRGAVTDFWNMDKSGK
                     K"
     gene            complement(23202..24134)
                     /locus_tag="ACL29Z_001143"
     CDS             complement(23202..24134)
                     /locus_tag="ACL29Z_001143"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase family protein"
                     /protein_id="HGR0069462.1"
                     /translation="MMRSTKELRHVYRDFLLEANQSDSDIVVLEADLSSSMATHNLEK
                     DFGDRYVNVGIMEAEMVGLAAGLSIQGFRPYLHTFGPFSSRRVFDQLFISLGYAQLDA
                     TVIGSDAGVTAEMNGGTHMPFEEIGLLRLIPKSIIFEATDDIQFREILNQTLDLKGLK
                     YIRTIRKAPVPVYQGGEDFSKGYIELRHGEDLVIVASGIMVAPSIRVADELSKLGYSV
                     GVIDLFRIKPIPEQIKTMLSGKTIFTVENHNQIGGIGSALCELFSDDGITKIHRMGVQ
                     ERFGQVGKMDYLLNEYGLSESNIKEKVLEFYNAR"
     gene            complement(24131..24988)
                     /locus_tag="ACL29Z_001144"
     CDS             complement(24131..24988)
                     /locus_tag="ACL29Z_001144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase"
                     /protein_id="HGR0069463.1"
                     /translation="MILSKNREDGLRKFATNIRLNTLRTLNHLGFGHYGGSLSIVEVL
                     AVLYGEIMPMTPEIFAARDRDYFILSKGHGGPALYSTLYLNGFFDKEFLYSLNTNGTK
                     LPSHPDRNLTPGIDMTTGSLGQGISVATGLAYGQRIRKSPFYTYAIVGDGELNEGQCW
                     EAIQFASHQQLSNLIVFVDDNKKQLDGFTKDICNPGDFVEKFSAFGFESIRVKGSDIR
                     EIYEGIVQLKQSNNSSPKCIVLDTIKGQGVQELEEMKSNHHLRPTVEERQMLTSVVER
                     LSQELEETE"
     gene            complement(24992..26338)
                     /locus_tag="ACL29Z_001145"
     CDS             complement(24992..26338)
                     /locus_tag="ACL29Z_001145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000975284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS ascorbate transporter subunit IIC"
                     /protein_id="HGR0069464.1"
                     /translation="MMKFILDIVSTPAILVALIAILGLVLQKKKLPDIIKGGIKTFVG
                     FLVVSGGAGIVQNSLNPFGTMFEHAFHLSGVVPNNEAIVAVALTTYGSATAMIMFAGM
                     VFNILIARFTRFKYIFLTGHHTLYMACMIAVILSVAGFTSLPLILLGGLALGIIMSIS
                     PAFVQKYMVQLTGNDKVALGHFSSLGYWLSGFTGSLIGDKSKSTEDIKFPKSLAFLRD
                     STVSITLSMAVIYIIVAIFAGSEYIEKEISSGTSGLVYALQLAGQFAAGVFVILAGVR
                     LILGEIVPAFKGISERLVPNSKPALDCPIVYTYAPNAVLIGFISSFVGGLVSMAIMIA
                     SGTVVILPGVVPHFFCGATAGVIGNASGGVRGATIGAFLQGILISFLPVFLMPVLGGL
                     GFQGSTFSDADFGLSGIILGILNQFGSQAGIVIGLVLILAVMFGVSFIKKPSATEE"
     gene            complement(26351..26635)
                     /locus_tag="ACL29Z_001146"
     CDS             complement(26351..26635)
                     /locus_tag="ACL29Z_001146"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008089859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HGR0069465.1"
                     /translation="MLKIGTACGSGLGSSFMVQMNIESVLSDLNVSDVEVEHYDLGGA
                     DPNAADIWIVGRDLADSASHLGDVRILNSIIDMDELRELITKICEEKGLI"
     gene            complement(26639..28669)
                     /locus_tag="ACL29Z_001147"
     CDS             complement(26639..28669)
                     /locus_tag="ACL29Z_001147"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000460919.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HGR0069466.1"
                     /translation="MFDYRALVILMTLMDHCELSLYELSVKVSLPIKEVKEGIDYLVP
                     YLANKGIVLDKKQGRYSLSNRTKQSLTDIIKSDELVLPKSTRLALIYLYTFCRLDFIS
                     NNHYQDFLKVSKNTTLSDIQSLRKIMLDNDLELGYSRAKGYTLHGSEWNKHRLAFQMV
                     SELLESSIGIWGLDYVLSSWGYSLTYDLIDQVVKDYYEKLQLVPIVNQLKVYLFGLVF
                     ILCRYQRDVERVCLSETLVSPVIQDITTILLDTVVDLGIIDTVFSEDDYRYITVLLSS
                     CFEGEVDVAPVYFNQLTEAIISRMEDISLLHFKQREGLRENLRRHLIPAYYRLKFGLP
                     SSNEYVLHVKEHYPDLFELVKDSLMPLMDAIDNPIPDSETAYFVIHFGGYLKKADTLP
                     QKWYKAAIICPNGVSSSLMLKENLLALFPQIEFIGTSKIDDLQVKASSDYDMVFSTIK
                     VETEKPNYLVSVMMTEEQAIQLVELVLKDFPNLEYGDFEIEQILNIVKRYGIITQELE
                     LRLALKNYLYQKNDRKEIVPVLEQLITKETYQVSSQKLGWKEAIRLAAKPLLDQDKIT
                     ENYPEAMIQKVEEFGPFINLGKGVAIPHARPDEGVNEIGMSMLVLEEPIYLLDNPEQE
                     VRLLICIAAIDNESHLKALSHLTTILRDKNHVQTLISSKNYDDIKMIIKQED"
     gene            28860..29867
                     /locus_tag="ACL29Z_001148"
     CDS             28860..29867
                     /locus_tag="ACL29Z_001148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000136853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPFH domain-containing protein"
                     /protein_id="HGR0069467.1"
                     /translation="MTEKLINSKPNGVFALILIELTIILGIFIFIMGVGSENIFGIII
                     GPLLIVIAGLAHAGLKVVKPQEALVLTLFGNYTGTIKEPGFYFVNPFSVAVNPANHTR
                     LGQSGDVSTKSPFLGAKSSNDNDVNLEIGKKHISLKVMTLSNSRQKINDCLGNPVEIG
                     IAVTWRVVDTAKAVFNVDNYKEYLSLQCDSALRNIVRIYPYDVSPNVDTTGDGQADEG
                     SLRGSSEIVANRIREEIQSRVEDAGLEILEARITYLAYAPEIAAVMLQRQQASAIIDA
                     RKMIVDGAVGMVEMALERLNEGELVELDEERKAAMVSNLLVVLCGNHDAQPIVNTGSL
                     Y"
     gene            29870..30070
                     /locus_tag="ACL29Z_001149"
     CDS             29870..30070
                     /locus_tag="ACL29Z_001149"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399403.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS ascorbate transporter subunit IIC"
                     /protein_id="HGR0069468.1"
                     /translation="MAEAKKKQIPLRLSTKLYAALASWAEDDFRSVNGQIEYLLTECV
                     KQRKKDGKYVSETIDEPFEIDI"
     gene            30222..30404
                     /gene="rpmF"
                     /locus_tag="ACL29Z_001150"
     CDS             30222..30404
                     /gene="rpmF"
                     /locus_tag="ACL29Z_001150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000290417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015934 - large ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L32"
                     /protein_id="HGR0069469.1"
                     /translation="MAVPARRTSKAKKNKRRTHYKVTAPSVNFDETTGDYSRSHRVSL
                     KGYYKGRKIAKAASAE"
     gene            30420..30569
                     /gene="rpmG"
                     /locus_tag="ACL29Z_001151"
     CDS             30420..30569
                     /gene="rpmG"
                     /locus_tag="ACL29Z_001151"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001265622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HGR0069470.1"
                     /translation="MRVNITLEHKESGERLYLTSKNKRNTPDRLQLKKYSPKLRKHVV
                     FTEVK"
     gene            complement(31061..>31213)
                     /locus_tag="ACL29Z_001152"
     CDS             complement(31061..>31213)
                     /locus_tag="ACL29Z_001152"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000753868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0069471.1"
                     /translation="WYYLNESGSMATGWFTVSGKWYYTYNSGDLLVNTTTPDGYRVNA
                     NGEWVG"
BASE COUNT         9723 a         6164 c         6291 g         9035 t
ORIGIN      
        1 acttttatga aatacagaaa acgcttccta aaacctaaag tttgtgatat aattatcaag
       61 aaaaaagatt taggagttta ttatggtttc ttcggaattt atctcaaaga ttgaatttgc
      121 ttgcaataag aaagaaagtc tttatagtca aagcaaattt aagtatgcga ttcgttcgat
      181 gttcgcaggt gcatttttaa ccttcagtac tgctgcaggt gcagttgggg ctgacttgat
      241 taataaaatt gcaccaggta gtggacgctt cctctttcca ttcgtttttg cttggggctt
      301 ggcctacatt gtttttttga atgccgagtt ggtcacttca aacatgatgt tcttgactgc
      361 tggtagtttc ttaaaaaaaa tctcttggag aaaaacagct gagattttac tatactgtac
      421 cttgttcaac cttatcggag ccttgatagc agggtggggc tttgctcatt cggcagccta
      481 tgcgaatctg acacacgata gtttcatctc aggtgttgtt gagatgaagt taggccgctc
      541 aaatgaattg gtcttgcttg aggcgatttt ggcaaatatt tttgtaaata ttgcgattct
      601 gtcatttatt ttggtcaaag atggtggtgc caaactttgg cttgtgttgt cagctattta
      661 catgtttgta ttcttaacaa acgagcacat tgcggcgaac tttgcttctt tcgcgattgt
      721 gaaattcagt gttgctgcgg attcaattgc caacttcggt gttggaaata tgcttcgcca
      781 ctggggtgtg actttcatcg gaaactttat cggaggaggc ctcttgatgg gtcttccata
      841 tgccttcctc aataaaaacg aagatactta tgtagattaa gaaaatgagc acgattgagt
      901 cgtgcttttt tcattttcaa aataaggtaa tagctatttc ttatatcaaa atatagaaaa
      961 ctgatatttg taaactataa ctcaaggtgc tacaatatcc ttaataaaat aatatggagg
     1021 tcaccttatg acttgtgatt ttaaatttga aactctacaa ctacatgctg gtcaagttgt
     1081 ggctccagct actaagtctc gtgcagtgcc gatttatcaa acaacatttt ttgtttttga
     1141 tgacacgtag gaaggtgccg atctgtttgc cttgaggaaa ccagggaaca tttatactcg
     1201 tatcaccaat cctacaacag ctgcccttga aggtggtgtt gaagcgctag caacagcatc
     1261 aggtatgact gcagtgactt atacgatttt ggcgattgcc catgctggtg accatgtagt
     1321 ggctgcttcg actatttacg gtggaacctt caatcttttg aaagaacccc ttcctcgtta
     1381 tggtatcaca acaacctttt tcgatattga taatttggag gaagtagaag cagctatcaa
     1441 agacaatacc aagcttgtct tgattgaaac cttgggtaac cccttgatta atattccaga
     1501 cctggaaaaa ctggcagaga ttgctcataa acatcaaatc ccacttgtgt cagacaatac
     1561 ttttgcaaca ccttatttga ttaacgtctt ctctcatggc gttgacattg ccattcactc
     1621 tgtgactaag tttatcggtg ggcatggtac aactattgga ggaataattg tcgatagtgg
     1681 tcgttttgac tggacggctt cagggaaatt ccctcaattt gttgacgagg gtccaagctg
     1741 ccacaatttg agctatactc gtgatgtggg tgcagcagcc tttattatag ctgttcgagt
     1801 tcaattgctt cgtgatacag gtgcagcctt gtcaccattc aatgctttcc tcttgctaca
     1861 aagacttgaa acctcttcac ttcgtgtgga acgccatgta caaaatgctg agacaattgt
     1921 tgattttctt gtcaaccatc ctaaggtaga aaaggtaaat tatccaaaac ttgcagatag
     1981 tccttatcat gccttggctg agaaatactt gccaaaaggt gtcggttcac tctttacctt
     2041 ccacgtcaaa ggtggcgagg aagaagcacg caaggtcatt gataatttag aaatcttttc
     2101 tgaccttgca aacgcggcag atgctaaatc gcttgttgtc catccagcaa caaccactca
     2161 cggtcaattg tcagaaaaag acctagaagc agcaggtgtc acaccaaact aaattcgttt
     2221 gtcaatcggt cttgaaaatg tagaagattt gattgaagac ttgcgcttgg ccttggaaaa
     2281 aatttaaagt aaaagaagat aaacagtggg cttcgactca ctgtttttga ttttccctca
     2341 ggcatgatat aatggttaaa gaagtctaga aagaggaacg atatgaacga aatcaaatgt
     2401 cccaactgtg gggaagtctt tacagtaaat gagagtcagt atgccgaact cttgtcccaa
     2461 gtgagaacgg cagagtttga taaggaacta cacgatagga tgaagcagga actggccttg
     2521 gctgagcaaa aggccatgaa tgagcaacag actaaactgg ctcagaagga tcaagaaatt
     2581 gcgcaattac agagtcagat ccaaaacttt gatacagaaa aagaattggc caagaaagag
     2641 gttgaacaga caagccatga ggctctcttg gctaaggaca aggaagtaca gctcttagaa
     2701 aatcagttgg ctaccttgcg tttggagcat gaaaatcaac tacaaaagac cctttctgac
     2761 ctagaaaaag aacgggatca ggttaaaaac caactacttt tgcaggaaaa ggaaaatgaa
     2821 ttatctttgg cttctgttaa gcaaaactac gaagcccagc tcaaggcagc tagtgaacaa
     2881 gtcgagtttt ataagaattt taaggctcaa caatctacaa aagcgattgg ggaaagccta
     2941 gaacagtatg cagagagtga gtttaacaag gttcgtagtt tcgcctttcc aaatgcttac
     3001 tttgagaagg ataacaaggt ctcttcgcgt gggtctaaag gggactttat cttccgtgag
     3061 tgtgatgaaa atggagttga aatcatttct atcatgtttg agatgaaaaa cgaagcggac
     3121 ggaacagaga agaagcacaa gaatgcagat ttttacaagg aattgaacaa ggaccgtcgg
     3181 gagaagaact gtgagtatgc cgttttggtg accatgcttg aggctgataa tgactacttt
     3241 aacacaggga ttgttgacgt cagtcacgag tatgaaaaaa tgtatgttgt tcgtcctcaa
     3301 ttctttatcc aattgattgg tctcttacgt aatgcggcgc taaattccct aaaatacaag
     3361 caggagttgg ccttggttcg cgagcaaaat attgacatta cgcattttga ggaagatttg
     3421 gatgccttta agctagcttt tgctaagaac tataattcag cttcgactaa ctttggaaaa
     3481 gctattgatg aaatcgacaa ggccatcaaa cgcatggaag aggttaagaa attcctgacc
     3541 acatctgaaa accaactccg tttagctaac aacaaattgg aagatgtctc cgttaaaaaa
     3601 ttgacccgga aaaatccaac aatgaaagcg aagttcgaag cactgaaggg ggagtagaaa
     3661 gcaaaaatga acggtattat taacttaaaa aaggaagcag gaatgacctc gcatgatgcg
     3721 gtttttaaac tgcgtaagat tttgggaacc aagaaaattg gtcatggtgg aaccttggat
     3781 ccggatgtgg tgggtgtttt gccgattgcg gttggcaagg cgacacgcat ggtcgagttt
     3841 atgcaggacg agggtaagat ctatgagggg gaaatcactc tgggctattc cacgaagact
     3901 gaggatgcta gtggggaagt ggtcgcagaa acccctgttt tgtctctctt ggatgaaaag
     3961 cttgttgatg aagcgattgc tagcttgact gggcctatta ctcagattcc ccctatgtat
     4021 tcggcagtta aggttaatgg tcgcaagctc tatgagtatg cgcgtgctgg tcaggaagtg
     4081 gagcgtccag aacgtcaggt gaccatttat caatttgagc gaacaagtcc gatttcttat
     4141 gatggccaac ttgcccgatt cacttttcgt gtaaaatgca gtaaagggac gtacatccgt
     4201 actttgtcag ttgatttggg tgaaaagctt ggttatgcgg ctcatatgtc ccatttgact
     4261 cgtactagtg ctgctggctt acaattagaa gacgctcttg ccttggagga aattgctgaa
     4321 aaagtagagg ctgggcaatt agattttctc catcctttag agattgggac aggtgacctt
     4381 gtcaaagttt tcctaactcc agaagaggct acagaagttc gctttggtcg ttttattgag
     4441 ctagaccaaa cggacaaaga actggctgcc tttgaagatg ataaattgtt agccattcta
     4501 gaaaaacggg gcaatctcta taagccaagg aaggttttta gctagatcgt ttaggaataa
     4561 aaatcgggtg atagataaca attgcttgat aaaaccccat actaatagta gaatggtttt
     4621 gggaattata atattccaat tgttgcgagt tgtaggtact caaataatct atatagaaat
     4681 ttagaggtgt gaaatgaagc aatttaaaat tctttcagat aaatatttag agtccattac
     4741 aggttctgat gggaacttag gcccaggatt tggtgtgata attccatgat gcgaaatgag
     4801 tttcgagaaa gggtggagca acttcttcaa caaaaagaaa taaatgaaaa tagtgagttg
     4861 agtcacctgt ttcgtcttgc tatacaaaat ttagacagaa atgaaaaata ccaatcggtc
     4921 atggccaatt tgagtcaagg gttgtcactt tacctcatga cgcatcatta ccaggcacct
     4981 aagtctgtca ttgattttgg tttatggatt gccaaagctc ctagccagga aagagggaga
     5041 ctggctttct tgcagatgct tgctcaaacc ctacagggct ttcgttaaaa ctgtcgaaca
     5101 tcagagggaa gactctggtg ttttttgctg atgagactat aaattttgta aaaaatgtga
     5161 tagaatagac gacggataaa ataacggagg atagcatgca aaatagacca atcattattg
     5221 gagtgacagg tggttctggt ggtggtaaaa ccagtgtttc aagagccatt ttatcgcatt
     5281 ttcctgatga aaagatttcc atgattgagc atgattcata ctacaaggat cagtctcatt
     5341 tgacctttga agagcgtgtc aaaaccaact atgaccatcc ttttgccttt gatacagact
     5401 tgatgatcga gcagattaag gaattgttgg cagggcgtcc ggtggacatc ccgacctacg
     5461 actatacaga gcatacacgg agtagcaaga cctatcgtca ggaacctcaa gatgtcttta
     5521 tcgttgaggg tattttggtc ttggaggaca agcgtctgcg cgatttgatg gatatcaaga
     5581 tttttgtgga tacggatgac gatgtgcgca ttattcgtcg tatcaagcgt gatatggagg
     5641 agcgtggccg tagccttgat agcgttatta accagtactt aggtgtggtc aaaccaatgt
     5701 accaccagtt tatcgagtca actaagcgtt atgctgatat cgtcattcct gaaggggtta
     5761 gcaataccgt ggctatcgac ctgttgacga ccaagattgc aaagattttg gaagaagctc
     5821 gaaacagcaa ataatcacat gtggaggcct tgcctccttt ttctattttt ccctcataat
     5881 ggtacataaa tggagatttt taggcatatt tttggtataa taatacccat gaaagagcaa
     5941 gtaaatgaat agtaggtgga gatggaaaag tatttatcgg taacaacttt gaccaagtat
     6001 ctgaaaatga aattcgataa agacccatac ttggaacggg tctatttaac tggtcaagtt
     6061 tccaactttc gtaaacgacc tactcaccaa tatttctccc taaaggatga ccatgcagtt
     6121 attcaagcga ccatctggtc tgggatttat cagaaattag ggtttgacct ggaagaagga
     6181 atgaagatca atgtgattgg gcgtgtacag gtctatgaac caagtggtag ctactccatc
     6241 atcattgaaa aagctgagcc tgatggggtt ggggcgcttg cgattcagtt tgaacaactt
     6301 aagaaaaaat tgacagaaga aggcctgttt caagaacgct tcaagcaagc tctgccccaa
     6361 ttttctaaga gaattggtgt agtaaccagc cgtagtggag ccgttattcg agatattatc
     6421 acgaccgtca gcaggcgatt cccaggtgtt gacatccttc tttatccgac caaggttcaa
     6481 ggtgaagggg ctgcggagga aattgctaga aatattgcgc gtgctaatca acgggacgat
     6541 ttggatttgc tcattattgg tcgtggaggt ggttctattg aggatctctg ggcctttaac
     6601 gaagaaattg tggtacgagc tatttttgaa tctcgtttgc cagttatctc tagtgtgggg
     6661 catgagacgg atgtgacctt ggcagatttt gtggcagatc gacgcgctgc aacgccaaca
     6721 gcggcggctg aactggcaac acctgtgacc aagttggatg tattagctca tttgcaaaat
     6781 caggaaaaac ggatggtaac ggcagtccga aatgttctat ctaagaaaca agaggctttg
     6841 aaaaaatgca gtcagtctgt tatctttaga caacctgagc gcttgtatga cggttatttg
     6901 caacgcttgg accaactgca actgcgtttg aaacaaagtt tgcgaactcg gatttctgat
     6961 aacaaacaat tagttcaagc aagaactcat caattagtac aattatcacc tgttaccaaa
     7021 atccaacgct atcaagaccg tttaggacag ttggacaagc tcttaggtag ccaaatggcg
     7081 ttagtttatg acgccaaggt tgctgaggcc aagcgacttt cggaagcttt gctcatgttg
     7141 gatactagcc gaatcgtggc gcgtggttat gctattgtca aaaaagaaga gtccgttgta
     7201 gattcggttg agagtttgaa gaaaaaagac caagtaacgc ttttgatgcg agatggtcaa
     7261 gtagaattag aggttaaaga tgtcaaaaca aaagaaattt gaggaaaatc tagcagaact
     7321 ggaaaccatt gtccaaagtt tggaaaatgg tgaaattgct ctggaagatg cgattactgc
     7381 ctttcaaaag ggcatggtct tgtcaaaaga gctccaagct acgctggaca aggctgaaaa
     7441 gaccttggtc aaggtcatgc aagaagacgg aacagaaagt gattttgaat gaaaaagcaa
     7501 gaaaaattag ctcttgtcga gtcggctttg gaagattttt atggagacca gcagtttgcc
     7561 tctagtttac gggagtctgt tctctattct attcatgctg gtggcaagcg tattcggcct
     7621 tttctcttgt tagaagttct ggaagccttg caggttacca tcaaacctgc tcacgcgcag
     7681 gtagctactg ccttagagat gattcataca gggagcttga ttcacgatga ccttcctgct
     7741 atggatgatg acgattatcg aagagggcgg ttaaccaatc acaagaaatt cggtgaagct
     7801 atggccattt tggctggaga tgccttattc ttagactcat atgccttgat tgcgcaggca
     7861 gatttgccaa gtcagatcaa ggtggacttg attgccaact tatcccttgc ttcaggtagt
     7921 ctgggtatgg tagcagggca agttttggat atggagggcg aacaccagca cttgtctttg
     7981 gaagaacttc agactattca tgccaataag actgggaagt tactagccta tcccttccaa
     8041 gcggcagcta ttatagctga attgtcacct gaaatgcagg tgaagctgaa aactgtgggt
     8101 gaattgattg gacttgcttt tcaagtcaga gatgatgtac tggatgtgac agctagtttt
     8161 gaggaaatcg gcaagacacc tcaaaaggat ctgcaggcag aaaaatcaac ctatcctgcc
     8221 ctgttgggct tggaagagtc cattgccttt tgtaaccaaa ccctggatca agctaatgaa
     8281 aaattagaag aaattgccca gcagcttccc tttgaaacag aatcgattgt aagtgtagta
     8341 gaaagtttga gaatcaatgg ctaaggaaag agtggatgta ctagcttata aacaggggtt
     8401 gtttgaaacg agagagcagg ccaagcgagg tgtgatggct ggcctagtcg tagcagtcct
     8461 taatggagaa cggtttgaca agccaggaga gaaaattcca gatgacaccg aattaaaact
     8521 caagggggag aaactcaagt atgtcagccg tggtggtttg aaactggaaa aggccttgca
     8581 ggtctttgat ttgtcggtgg atggcgcgac tacgattgat atcggggcct ctactggagg
     8641 ttttaccgat gtcatgctac agaatagtgc caagttggtc tttgcagtcg atgttggtac
     8701 caatcagttg gcttggaaat tacgccaaga cccacgagtt gtcagcatgg agcagttcaa
     8761 tttccgctat gctgaaaaga ctgatttcga gcaggagccg agctttgcca gtattgatgt
     8821 gagtttcatt tcccttagtc tgattttgcc agccttgcac cgtgtcttgg ctgatcaagg
     8881 tcaggtggta gcacttgtca aacctcagtt tgaggcagga cgtgagcaga ttgggaaaaa
     8941 tggaattatt cgagatgcta aggttcatca gaatgtcctt gaatctgtaa cagctatggc
     9001 agtagaggta ggtttttcag tccttggctt ggacttttct cccatccaag gtggacatgg
     9061 aaatattgaa tttttagcgt atttgaaaaa agaaaagtca gcaagcaatc agattcttgc
     9121 tgagattaaa gaagcagtag agagggcgca tagtcaattt aaaaatgaat aaaaaagaga
     9181 gacttgaaaa aattagaaga ttggtgacag attatcaaat cggcacgcaa gaagaaattg
     9241 tagaacattt gaaagaagca ggtatcactg ccactcaggc gacggtatcc cgagatatca
     9301 aagagttagg tattgtcaaa attcctttga gagacaacac ctatgtctac gaattgccaa
     9361 aatcaatcgt aaaaagtctg caactggctg aagacaatat cgaatcggct gaattgatgg
     9421 ataagatgat caatctccaa gttattccag gaaatacggc ttttgtaaaa gctcagttaa
     9481 tcgagacttt tgcagacaag atttttagct gtttgactga tgatagctcg attttagtca
     9541 ttgccagaag tggaagtcta gcagaggaaa tctttgaaca agtaaaaaat tggtaggtct
     9601 atatgttact tgaaatttcg ataaaaaact ttgccattat tgaggctatt tccctcaatt
     9661 ttgaaaaggg gatgactgtc ctgactggtg aaacgggtgc agggaagtcg attatcattg
     9721 atgccatgaa tatgatgttg ggagctcgtg cgacgacaga tgttattcgt catggtgcac
     9781 caaaggcaga gattgagggg cttttctcag ttgagaatag tcgtctttta caggaaattt
     9841 ttgatgagca aggtttagaa ttaggtgatg aaattatcat ccgtcgggaa atcttgcaaa
     9901 atggtcgtag tatcagccgt gtaaatggtc agatggttaa tctgtctgtt ttgcgagcta
     9961 ttgggcaaca tcttgtagat attcatggtc agcatgacca tgaggagtta atgcgtcccc
    10021 aactgcatat ccagatgttg gatgaatttg gtgatgccgc tttttgggac ttgaaagaaa
    10081 cctatcaaac gagttttgat gcctatcgga aaatgcgcaa gcaggttctg gaagtcaaga
    10141 aaaaccaaca ggaacacaag gcacgtatcg aaatgttgga atttcaaatg gcagagattg
    10201 aggcagcaaa cttgcaggct ggagaagact tggctctcaa tcaagagcga gataaactcc
    10261 tcaaccacaa aaatattgcg gatacactga ccaatgccta cagtatgttg gacaatgaag
    10321 atttttcaag tctggccaat gttcgttcag ctatgaatga catggaaagt gtcgaagagt
    10381 atgatcctga ataccgtgaa atttcaagct ctctgtctga gacctactat gttttagaag
    10441 acattagcaa acgtttggaa gctatcattg aggaccttga ttttgatggc aatcgcctga
    10501 tgcaggttga gaatcgtttg gacctccttc atactattac tcgtaagtat ggtgggactg
    10561 ttgatgatgt tttgctttat tttgccaaga ttacggaaga atacaatctc ttgacaggca
    10621 ataatctttc gtctgaggac atggaagcag agcttaagaa gttggaagtc aatcttgtca
    10681 atttggcagg tcaacttgct tctgctcgtc ataatttggc tcagcaactc gaagctgaga
    10741 ttaaacaaga actgcaagat ctttatatgg aaaaagccca gtttcaggtt cgttttagta
    10801 agggaaaatt cagtcgtgag ggaaataaaa tggttgagtt ttatatttca accaaccctg
    10861 gagaagactt taaacccttg gttaaggttg cttctggagg ggaattatct cgtctcatgt
    10921 tagccattaa gtctgccttt tcacgtaaag aaggcaagac tagcattgtc tttgatgagg
    10981 tggatacggg agtttcaggt cgtgttgctc aagctattgc tcagaaaatt cataaaattg
    11041 gtcagcatgg tcaggttttg gctatctccc atttgccaca agtaattgcg attgcagatt
    11101 atcaattctt tattgagaag attagtaatg accattcaac ggtttcgact gttcgtctct
    11161 tgacggtcga agagcgagtg gaggaagttg ccaagatgtt ggcaggtgat gatgtgacag
    11221 aagcagccct gacgcaagca agagaattgt tgagaaacag ggagaaataa gatgacagat
    11281 tattatgtaa ttggagatgt tcacggaaaa gctgggatgc tggaagacct tctcaaaacc
    11341 tgggatggtc agccccagtt gctctttcta ggtgatttga ttgacagagg tgaggatagt
    11401 caccgtgttc ttgaaatggt caaggacttg gtggacaatc aaggggctat ctgtttgtct
    11461 ggaaaccacg agtatatgtt tttgacttgg ctagatgacc cagaagaaag ttatgaccat
    11521 tatagtcgca atggtggaga tacaaccatt aactctatcc taggtcgtcc cttggatgca
    11581 ccagttgatg gagtagaaga tgccaagcgg gttgccgctg aagcggcaga cttggtcgaa
    11641 ttcattcgtc aaatgccatt tgtagtagag acagacaagt atatctttgt tcacgcaggt
    11701 attgatttga ccttggacga ctggcatgaa acaacagatt ataaaaaagt atggcttaga
    11761 aaaccattcc acggagctga aaatcatact ggaaaaacca ttgtcttcgg tcatacaccg
    11821 gtctatggtt tgttacagca agaacgcggt acatctgagc tttggactac agaagatggc
    11881 aagattggaa tggatggagg agctgtttat ggtggtgtcc ttcacgggat tgtctttaca
    11941 gaccaaggaa tgacagaaca ccactttatc gaaaatgacg gctttgtcgc tgaagattag
    12001 tactcctagc agggtatggt cttgtcaaaa tatcaaaaac aatttataat aaatagatac
    12061 cctgaaagga agagaatcat gaacttagaa gaattgaaaa aacgacagga gaagatccgt
    12121 aacttctcta ttatcgccca tattgaccac ggaaaatcaa ctctagcaga ccgcattttg
    12181 gaaaaaacag agacggtttc aagtcgtgaa atgcaggccc agcttttgga tagcatggag
    12241 ctagagcggg aacgtggaat tactattaag ttgaatgcca tcgagttgaa ttacactgca
    12301 aaagatgggg aaacttatat tttccacttg attgacacac cagggcacgt tgactttacc
    12361 tatgaagttt cacgttcgct agctgcctgt gagggtgcta ttttggtggt cgatgcggct
    12421 caaggaattg aggctcaaac tcttgccaac gtttatctgg ctttggataa tgatttggaa
    12481 atcatgccta tcattaataa aattgacctg ccggctgcag atccggagcg cgtgcgtaca
    12541 gagattgaag atgtgattgg tttggatgcc agtgaagcag ttttggcttc tgccaaggct
    12601 ggtattggga ttgaagaaat cctcgagcaa attgtagaaa aagtaccagc accaacgggt
    12661 gatgtgacgg cgccacttaa ggccttgatt ttcgactctg tttacgatgc ttaccgtggg
    12721 gttatcctcc aagtacgtgt catggacgga gtggtcaaac ctggtgataa gattcagctc
    12781 atgagcaata gtaagacctt tgatgtggcc gaagtcggta tttttacacc aaaagcggtt
    12841 ggtcgtgatt tccttgcgac tggtgatgtt ggttacattg cggcgtctat caagacggtt
    12901 caggatactc gtgtgggtga taccgttacc ttggcaacca atcctgcggc agaaccatta
    12961 catggttata agcagatgaa tcctatggtc tttgcgggtc tctacccaat cgaatcaaac
    13021 aagtacaatg acctgcgtga agcgcttgaa aaattgcaac tgaatgatgc tagtcttcag
    13081 tttgaaccag aaacatctca ggcacttgga tttggtttcc gttgtggatt tcttggactt
    13141 ctccatatgg atgttatcca ggaacgttta gagcgtgagt tcaatattga cctcatcatg
    13201 acagctccgt ctgttattta caaagttaat ttgaccgacg gtgagtctat ggatgtgtct
    13261 aacccatctg agtttccaga cccaactaag attgcgacca ttgaagagcc ttatgtcaag
    13321 gcgcaaatca tggtaccaca ggagttcgtc ggagcagtaa tggagctagc tcagcgtaag
    13381 cgtggggact ttgtgactat ggactatatt gatgataacc gtgtcaatgt tatctatcaa
    13441 attcctcttg ctgaaattgt ctttgacttc tttgataaac ttaagtcttc gacacgtggt
    13501 tatgcaagct ttgactacga attgtcagaa tatcgcccat ctaagctggt gaaaatggat
    13561 atccttctca atggagataa ggtggatgcc ctcagcttta tcgttcacaa ggactttgcc
    13621 tacgaacgtg ggaaactcat cgttgataaa ctcaagaaaa tcatccctcg ccaacaattt
    13681 gaagttccaa tccaagcggc tattggacac aagattgtcg ctcgtactga tatcaaggcc
    13741 cttcgtaaga acgtacttgc taaatgttat ggtggtgacg tttctcgtaa gcgtaaactc
    13801 cttgaaaaac aaaaagctgg taagaaacgc atgaaatcca tcggatcagt tgaagttccg
    13861 caagaagcct tcctcagcgt cttgagtatg gatgaagaat aagttatcag aaatgccttt
    13921 ccttgttcac aggaaattta tataagaatc aatagtaaag caggcttaga tggtctgctt
    13981 ttttagtttt tatactcttc gaaaatctct tcaaaccacg tcagcgtcgc cttaccgtat
    14041 gtatggttac tgacttcgtc agtttcatct acaacctcaa aaccatgttt tgagctgact
    14101 tcgtcagttt catccacaac ctcaaaacag tgttttgagc aacctgcggc tagcttccta
    14161 gtttgctctt tgattttcat tgagtataat acaaaaatcc gatgaacttc accggactct
    14221 tttattttga atttttgcct gctttacgct tttcagcgat ttcggctgcc tttcgaggca
    14281 agacaatttc cgttatgtaa gccgtcccaa aacgcagtac acctgcaata ggagcaaaga
    14341 caactgctag atagttatag aagaaatcgc ctttgaaggc ataagctagc gctccaatga
    14401 tgaaaaatag aacgactgcc tgaatcactg ctaataaaat tactcgtttc atgtgacctc
    14461 ctgactctat tatagcatga gaatcatcaa aaagccgact aaattattca aagcgtgaag
    14521 agaaatactg tagaccagac cttttctgct aatgtaagcc aaacccaaac taaaaccaag
    14581 gctaaaatag acaaaaaatt gttgcacatc acctggaaaa tgaatcaagg caaatagaag
    14641 actagatacc agaagaaaaa tcagggttcg tttactattg tcctgcttag gaaagagata
    14701 gcgtgctaac atccctctaa aaacaatctc ttccgtcaaa ggagcaaaaa taaccacagc
    14761 aaagaatgag aaaagtggtt gagacaaggt caagtctgtc gctatttgct gatttactga
    14821 aggatcatct ggcaagaaga attgaacgac cagagataag aaccaaacca agacaggaag
    14881 ccaaataaat cggttaaagc cgctcttctc aatatgaaca ggagccttct gataccattt
    14941 gtaaatgccg tacacatata ctacagccaa ggccacatag agtagagtaa cagcataggg
    15001 tgaagcgcct aaagcaagcg acgcagtcgc gagcccctga ataaagccat agataaataa
    15061 aaaggataga agggctagaa gaatccagcc aaggttttta agtaatttca tagataactc
    15121 ctttatttga aataacgttt taccataggt aactgcatca cattgatata aacatggatg
    15181 gctcctacaa gcaagaaagc tagtaactga atctctcctg tcaagaaaga aatgataata
    15241 agaaaaatat ataaggctgg taagatatat tggtgtaatt ggaataaaat tcgaaaactc
    15301 tgttccaaat tagcctgacg ctccccttca tcataagaat ttatatagtt caagacatcc
    15361 tttggtgtag cgaaaaattc caaatcaaac tgacgaacaa tcgcaatggt tttaaaaaga
    15421 gatttttgag cgactaagaa taccacaaag agtaagaaag aaaggaaaaa tgtttgaggg
    15481 tttgtatgca atataatcac ctcacttaat gaaataaaaa tagccaatgg aatcgctaca
    15541 cctgtaatat taaaagcaat ggttccaaac tcaagattcc gatacatttg cacataatag
    15601 gtttcattca gatcgtcatc catttcctct tgatacaagg aatgaaattt tctgcttttc
    15661 tttaagaaat tgaaagtcaa aaacatacta atgaaaccta tcagtaaaca aatagctgat
    15721 atccatggca tcaaggcttt tacatctaaa ataatttcgt gggattcgac acgtgcctta
    15781 aacatcccta caaacatgcc caagaacccc cccaagacaa tagacatcaa aaataacaat
    15841 ctacgtttct ttttcatatt cattctcctt tttcacttgc tagatttttg gatttctttt
    15901 caatccattc aattactggg atgagagcaa agtagaccca aacaaattgg tcgctttgat
    15961 agggattaaa ccagcttagg tccatcccaa tcagtagaaa tacgctgact aataaagcta
    16021 tgaccactac ataataaatc actttatact tgttcatcac tcgtcctcct ccaaacgaaa
    16081 taccgattcg actgtttcgt tgaaaatttg agatattttc agggcaatga taatggatgg
    16141 ggtgtactca tcccgttcta gtaggctaat ggtctgtctg gaaacccctg ccagtttggc
    16201 taggtcggtt tgattgagac catcgcgagc tcgaagctct tttagacgat tttttagttg
    16261 cacgttacac acctactctc cgtcaaattc aacggtttgg atatcttcaa tacgttgcaa
    16321 cttgaatttt tcttttcccg tattatctac acgtcgtagc tttacccatt cctcatcaac
    16381 atccacaact tcccagttat ctggcccaat atacactccc gttataattg gtttctttcc
    16441 aatcatttct tgcaataatc tcgacatttc tgcgtttcct ttctcttttc gctcaagttt
    16501 tttgatttta ttctctagtt tcttgatttt tttagaatta ttagaataaa agaaaataat
    16561 aaatagtata aatactagta cccacatcat agctcctttc ttcttttctc ttaacttgct
    16621 tacattgtaa cacatctttt tctttttgac aagtatagct gtcaaaaagt ttatgatttt
    16681 tgtcattttg caaaagaaaa aggtcaggag taagttcctg accactttat ctatcattaa
    16741 tactcttcta aaatctcttc aaaccacgtc agtttcatct acaacctcaa aaccatgttt
    16801 tgagcaacct gcggctagct tcctagtttg ctctttgatt ttcattgagt ataaaatcct
    16861 agtttttcaa agatttctga gaagttttgg ctgattgtct caagtgacac ttgcacttct
    16921 tctcgggttt ggttgttctt gactgtcact tgtctgcttt cgacttcgct ctctcctagg
    16981 gtgatgaggg tcttagccgc aaagacatcg gctgacttga actgagcttt gagcttacgg
    17041 ttgaggtaat cacgctctgc tttgaaacct tgttggcgaa gagcttggac tagttctagg
    17101 gctttgacat ttgctccatc acccaagact gcgatataga catctagggc attttcgata
    17161 gggagggcca cgccttgttt ttcaaggatg agaagcaggc gctctacacc aagcccaaaa
    17221 ccaaatccag cagtttcagg gcctccaaag taagcaacca aaccatcgta gcgaccaccc
    17281 gcacagactg tcaagtcatt gccctcaatc tctgtgataa actcgaaaat ggtgtggttg
    17341 tagtagtcca gaccacgtac catattggta tcgatgatgt aatctactcc aagattttcc
    17401 aacatctgac gcacagcatc aaaatgagtt tggctttctt catcaagaaa gtccaagata
    17461 gacggcgcat tctctactgc caccttgtct tctttttcct tagagtccaa gacacgaaga
    17521 ggattttcct ccaagcgacg ttggctatcc ttagacaagg tctccttgag cggtgtcaaa
    17581 tagtcaatca aggcttggcg gtaggctgca cggctctcag gatttccaag agtgttgagg
    17641 tgcaatttga caccttgaat accgatttcc ttcaaaaaat gggctgccat agcgattgtt
    17701 tccacatcgg tagctggatt gctagagcca aaacactcaa caccaatctg gtggaattgg
    17761 cgcaagcgcc ctgcctgtgg acgctcataa cggaacatag gtcccatata gtagaacttg
    17821 cttggctttt gcacttctgg ggcgaaaagt ttattttcca cataggaacg gacaacgggt
    17881 gcagttcctt ctggacggag ggtaatatga cggtcaccct tgtcataaaa atcgtacatt
    17941 tccttggtta cgatatccgt tgtatctccg acagagcgac tgataacctc gtaatgctca
    18001 aaaataggcg tgcgcacttc tgcgtagttg tagcgtttga aaatttcacg ggcaaagccc
    18061 tcaacgtact gccacttggc agattcagca ggtaaaatat cctgcgttcc ttttggtttt
    18121 tgtaatttca tagggaatcc tctttaaact taatagtctt attttaccat aaatagaggg
    18181 attaaaacag tgagaaaaaa attaggattt agatatcatt tttgagatta agaattgtta
    18241 aaaaaatagc tagcaaggaa agaccaacaa atagcatcca agtcaactgc atgttccata
    18301 cggctactag tgaaaaacaa gctgttccca caggtatgga taaggtaaac aatagaccta
    18361 aaaaattact agtaggagct agaacctctg gagctagatt tttcatgagc atggcactaa
    18421 tctttggttg aactttacca gacacataca gagtaaagaa gagaaatagc aaaccaagca
    18481 cgacttgatt gaataaatta gccaaaccaa aaggactgct tcccaaaata atcattgccc
    18541 gtaaggctac tgatgatgac tgctactaaa acacagaatt gattgataaa tagtgcctct
    18601 gtataagaaa aattcaagag agaatggctc aaaaagaaga tattataaat tccacccaaa
    18661 gcgccaccca aggaattaat aagcaagaca gcaaagagca taaaaccaaa gtttttctgt
    18721 ccacttttaa gaaaaacgag acgtaaattt cggtaaattg ttaggaactg gtctttgata
    18781 gaaagcttct cattttttag tttttcacca tcagcagatg aaattgacag gctcaatttg
    18841 ctttttccta aaaaaagaat aaaggctgat acgaggaaaa agcaagcatt aattcccgca
    18901 acgagggaaa aattgttgac cgatagagct aagagccaga ctccgaaagc ttgaccacca
    18961 atagctgaaa tataggtgat gaactgtgaa aaagaataag cctccatcag atcatcttca
    19021 gctacttttt ccttaataag aggcatacgc aggccacctg caaaatcact gatgatatca
    19081 ctaatgacat tgatcaaaca caggctagaa aaggcaaaga gactagcttg ctgaacaact
    19141 agggctgcta aaaaaaatag aaccgcctga aacaaaccgc tatagaccat ccatttgacc
    19201 ttgtccctcg tgtaatctgc ccgaatccct acaaaaactg taaagagggt cggaagaatc
    19261 atgacaatat tcgccatagc aacagcaaaa gatgcttgtg acaaggtcga tgcatagacg
    19321 ataaagacca ggttgaaaat cgaagcacca aaagcattga agaagcgtga taaagtcaaa
    19381 attctataag ctggatttct aaacaatagt ttcatagata atctccctcc ttgttctaag
    19441 ttctacatca agaatagctt tagtatagca cttatgaatt tgcgaaacga ttcttttgaa
    19501 tatatgcaac aaacaaaatg agcaaaaaaa cgatagaact tttgtaatga cctgagagag
    19561 ggcaacagtt ctatcgcttc aaattttttc ttggtttgca gatattcaag aatcgagagt
    19621 ttttctatag tattcggcag atttattaca gcccagcatc tcaaaaatac ggacagcatc
    19681 ctccatcttt ttctggcctt ccttgactct accttgcttg ctatcaagga gaccttctgc
    19741 ccacagataa acaattcgga aataggtctc attttccttg tagaaatgct cttcgataac
    19801 acgtttaaaa taataggcat tggtaaattc ttcacactca atactagcta aaaagccatt
    19861 caatagtata gtatgaaaaa ggtttcgatt gccagacatt tccattagaa aatcagattt
    19921 acgtaccatt tctcgtacat atctagtaaa aagagaaaca gataaaaatg gagaactgac
    19981 tgaaaataaa ttgagttcat agattcccca gatctcggta gaaaacaaat aatcatgaag
    20041 gacttttcct tcctctgctg ttaactctac cctttcatct atgctcttca tataagactt
    20101 gataataatg gcatttagaa tatgtttctg tttgttgtga gaatgggcat gcttttgata
    20161 ctccctgcga tataagtcct caagaggtgc tatattcttt ggttccaaga catctgtaat
    20221 ttcttttctc aactcagaat ctgtatcata ctggaaacct ctcgccagaa agaggatctc
    20281 ctccacactg gcagatatat tttccagagc aaatagaaac ttttccaccg aaagctcact
    20341 ctgacctgtt tcaaaacggg acaacataga cggcgaaaat tgtcctccgg ttgcttgtct
    20401 cagtgagata tttcttgact ctcgtaattg tctaaagact tttccaatct gctccataga
    20461 cttccccttg attccgtatt ttcttcattt tatcatattt ttcagaaaat tcatcaaaaa
    20521 cttgccaaat tgtcagaatt atgagaaaat agaggatatt tatcacgtgg agggactgct
    20581 atgagagacg atatcaaaat caatgaccgt gctttggcct tgcaagacca aattatcgaa
    20641 aaactagaga aagtttttga tacagatgtg gaattggatg tttacaatct aggtctgatt
    20701 tatgaaatca atctggatga aacggggctc tgcaagattg tcatgacctt caccgatact
    20761 gcctgtgatt gcgccgaaag cctgcctatt gaaattgtgg caggtctgaa acaaatcgag
    20821 ggtatcaaag atatcaaggt tgaagttacc tggtcgcctg cttggaaaat cacacgaatc
    20881 agtcgctatg gccgtattgc ccttggacta ccacctcgtt aagcaggcca atcactttta
    20941 aagatgaaaa aagcaagccg aaaatggctt gctttttgat actcaatgaa aatcaaaggg
    21001 caaactagaa aactagccgc aagttgctca aaacactgtt ttgaagttat ggatagaact
    21061 gacgaagtca gctcaaaata ctgttttgag gttgtagata gaactgacga agtcagctca
    21121 aaacactgtt ttgaggttgc agatagaact gacgaagtca gctcaaaaca ctgttttgag
    21181 gttgtagata gaactgacga agtcagtaac catacctacg gcaaggcgac gttgacgtga
    21241 tttgaagaga ttttcgagta tgagtttatt ttttacctga cttgtccata ttccagaagt
    21301 ctgtcacggc tccgcgtgaa gcagatgata cgatgtgggc atatttaccg aggacaccac
    21361 ggctgtaaag tggtggcaag gttgtttctg ccttgcgttt ttcaagttct tcttcggata
    21421 cggccatgga aatttctttg gtatcttggt caaccgtaac gatatcgccg gtacggagat
    21481 aggcaattgg tccaccatcc tgagcttcag gagcgatatg tccaacaacc agaccataag
    21541 taccaccaga gaaacgtccg tccgtcaaga gggccacctt atctccctga cctttaccaa
    21601 caatcattga agaaagtgac agcatctcag gcataccagg accaccttta ggtccaacaa
    21661 aacgaacaac gactacatcg ccatcaacga tttcatctgt caggacggcc tgaatcgcat
    21721 cttcttctga gtcaaagacc ttagctggcc caacgtgacg acgcacttta acacctgata
    21781 ccttggcaac tgcaccgtca ggagcaaggt tcccgttcaa gatgataagc ggaccatccg
    21841 cacgttttgg attttcaagt ggcatgataa ctttttggcc tggagtcaag tctgcaaagt
    21901 cagccaagtt ttcagctaca gtcttaccag tacatgtgat gcgatctccg tgaaggaaac
    21961 catttgccaa caagtacttc ataaccgcag ggacaccacc gacttcgtag aggtcttgga
    22021 agacatactg accagatggt ttcaagtcgg ccaagtgagg cacacgttct tgaatcgtat
    22081 tgaagtcctc aagtgacaag tcaacatttg cggcatgggc aatggcgagc aagtgaagag
    22141 tggcgtttgt agaaccaccg agagccatcg ttacagtgat agcatcttca aaggcttcac
    22201 gagtcaagat atctgatggt ttgagaccaa gttccaacat cttaacaaca gcacgtcctg
    22261 ctgcttcgat atcttctttc ttatcagctg attcagctgg gtgagaggat gaccctggca
    22321 aactcatccc tagaacttcg atagcagttg ccatggtatt agcagtatac ataccaccac
    22381 aaccaccagg gccagggcag gcattacatt caagacgttt cacgtcctca gctgtcatgt
    22441 caccgtggtt ccattttccg ataccttcaa agacagaaac caagtcgata tctttaccat
    22501 caagatttcc cggtgcaata gttccaccat aggcgaaaat ggctgggata tccatgttgg
    22561 caatagcaat catagatcca ggcatgttct tgtcacagcc accgatagcg acaaaggcat
    22621 cgacattgtg accactcata gccgcctcga tggagtccgc gatgatgtca cgagatgtta
    22681 gagagaaacg cataccaggc gttcccatag cgatcccgtc tgctacggta atagttccaa
    22741 actgtacagg ccaagcgcct gcagatttga caccttcttt agccagtttc ccgaaatcat
    22801 gcaagtgaat gttacatggt gtattttccg cccaagtcga aatcactccc acaatcggtg
    22861 tttcaaagtc cttatctgtc ataccagtcg cacgaagcat agcacggtta ggtgatttaa
    22921 ccatgctgtc atagatgcta ctgcggtgac gtttatctaa ttcagtcatc ttatccctcc
    22981 catttcagtt tttactatta tagcacaatt ttcgcatgaa gaacagaata aaattcttga
    23041 attttcagaa aattctatac acatgtgaaa tatttaaaat taaaaacaac aaagcggatt
    23101 agtgcacttt ctgatgacca gaatatgctt tttaatccgc tttctttaaa taacgtaatg
    23161 taatttttac agaaattctt tcagaacagt gtatttaaca tctatcttgc attataaaac
    23221 tctagaacct tctcttttat attcgattca ctcaaaccat actcattaag aagataatcc
    23281 attttcccta cttgaccgaa tctttcttga acacccatcc gatgaatttt tgttattcca
    23341 tcatcagaga ataattcaca taaagcactg ccaattccac ctatctgatt gtggttttct
    23401 acagtaaata tagtttttcc acttaacatt gtttttatct gttctggtat cggtttgatt
    23461 ctaaataaat ctatcacacc tactgaataa cctaatttag acagttcatc tgcaactcga
    23521 atacttggag caaccattat gccagaagca acgattacaa gatcttcacc atgtcttaac
    23581 tcaatgtagc ctttagaaaa atcctctcca ccttgataca caggaactgg agcttttcta
    23641 attgttcgaa tatattttag tccttttaag tctaatgtct ggttcaatat ttcacgaaat
    23701 tggatatcat cagttgcttc aaaaatgatc gatttaggaa ttaaacgtaa caatccaatt
    23761 tcttcaaatg gcatatgtgt cccaccattc atttctgcag ttactcctgc atctgatcca
    23821 atcacagtgg catccaattg tgcgtatcca agagaaataa ataattgatc aaatactctt
    23881 cgtgaagaaa aaggaccaaa tgtatgaaga taaggtctaa acccctgaat agacaagcct
    23941 gctgcaaggc cgaccatttc tgcttccata atcccaacat tcacataacg gtctccaaag
    24001 tccttttcaa gattatgagt agccatcgaa cttgacagat cggcttctaa gactactata
    24061 tcagaatcac tttgattagc ctctaaaagg aagtctctat atacatgccg taattctttc
    24121 gtacttctca tcattctgtt tcctccaatt cctgacttaa tctttctaca actgaagtta
    24181 acatttgtct ctcctctaca gtagggcgaa gatgatgatt ggatttcatt tcttccagct
    24241 cttgaacccc ttgaccttta atagtatcta atacaatgca cttaggtgat gaattatttg
    24301 actgttttaa ttggacaatc ccttcataaa tttctctaat atctgaaccc ttgaccctaa
    24361 tggattcaaa tccaaatgct gaaaattttt ctacgaaatc acctggatta caaatatcct
    24421 ttgtaaaacc atctaattgt tttttgttat catcaacaaa tacaattaag ttggataact
    24481 gttgatgaga agcaaactgt atagcctccc aacattgtcc ctcatttaac tcaccatctc
    24541 caacaatagc ataagtataa aagggactct ttcttattct ctgaccatat gcaagtccag
    24601 ttgcaacact aattccttgt cctaaagagc ccgttgtcat atctatgcct ggcgttagat
    24661 ttctatcagg atgagacggt aatttggttc catttgtatt taaagaatat aagaattctt
    24721 tgtcaaagaa accattcaaa tagagtgtac tgtatagagc tggtcctccg tgaccttttg
    24781 ataatatgaa ataatctcta tctcgtgctg caaatatttc tggagtcatt ggcattattt
    24841 caccataaag cactgctaaa acttctacga tagacagact tcctccgtaa tgtccgaatc
    24901 caagatgatt caatgttcta agagtattta atcggatgtt agtcgcaaat tttcttaacc
    24961 catcttctct atttttactt aaaatcatcc cttattcctc cgttgcagat ggctttttaa
    25021 taaaggatac tccaaacata actgctagaa taagaacaag accaatcaca atgcctgctt
    25081 gtgagccaaa ttgatttaat attcctaaaa taattcctga tagaccaaaa tctgcatctg
    25141 agaaagttga tccttggaaa ccaagtcctc ccaaaactgg cattaaaaag actggaagaa
    25201 aactgattaa aataccttgt aaaaatgctc caatagtggc tccacgaaca ccaccagatg
    25261 cattcccaat gacacctgca gtcgctccac agaagaaatg aggcacaaca cctggtaaga
    25321 taacaaccgt tcctgaagca atcataattg ccatacttac taaaccacca acaaaactag
    25381 agataaatcc aattagaact gcattgggtg cataagtata aacaatcgga caatccaaag
    25441 caggttttga attaggtaca agacgctctg aaataccttt aaaggctgga acaatttcgc
    25501 ccaaaataag gcgaacacct gctaaaataa caaatacccc tgctgcaaat tgacctgcta
    25561 attgtaaagc ataaactaga ccacttgtac cactactgat ttctttttct atatattctg
    25621 accctgcaaa gatagctaca ataatgtaaa taactgccat agataaagtg atactaacag
    25681 tactatcacg taaaaaagct aaactctttg gaaatttaat gtcctctgtt gattttgatt
    25741 tgtcaccgat aaggctacca gtaaaaccac tcaaccaata tcccaaagaa ctgaaatgac
    25801 ctaaagccac cttgtcattt ccagttaatt gaaccatata tttttgcaca aatgctgggg
    25861 aaatactcat aataataccg agtgctaatc ctcctagtaa gatgagaggc aagctagtaa
    25921 agccagcaac tgataaaatg accgcaatca tacatgccat atatagagtg tggtgccctg
    25981 ttaaaaagat atatttaaat cgagtaaaac gagcgattaa gatattgaac accatgcctg
    26041 caaacataat cattgcagta gctgagccat atgttgttaa agctacagct acaattgctt
    26101 cattattcgg cacaacgcca gataaatgaa aagcatgctc aaacatggta ccaaatggat
    26161 ttaaagaatt ttgtacaatt cctgcaccac cagatacaac taagaaacca acaaaggtct
    26221 taattccacc tttaataata tcaggtaatt tcttcttctg aagaactaat cctaagattg
    26281 caattaaagc tactaaaata gctggtgtac taacaatatc caatatgaac ttcatcatga
    26341 cgctagcctc ctatataagt cctttttctt cacaaatttt agtaattaat tctcgtagtt
    26401 cgtccatatc aataatacta tttaagatac gaacatctcc aagatgacta gctgaatcag
    26461 ctagatcacg accaacaatc caaatatcag ctgcatttgg atctgctcca cctaaatcat
    26521 aatgttcaac ttctacatcc gaaacattca aatcactcaa tacagattca atattcatct
    26581 gtaccataaa acttgaacct aatcctgaac cacaagctgt accaattttt aacattatct
    26641 aatcctcctg tttaattatc attttaatat catcatagtt ttttgatgat attaaagttt
    26701 gaacatgatt tttatctctt aaaattgttg ttaaatgtga caaagccttt aaatgactct
    26761 cattatcaat ggctgcaata caaatcaaca atcttacctc ttgttctgga ttatccaata
    26821 aataaatcgg ttcttccaaa actaacattg acattcctat ttcattcaca ccttcatctg
    26881 gccgagcgtg aggaattgct actcccttcc ctaaattaat aaaaggtcca aactcttcta
    26941 ctttttgaat cattgcctca gggtagttct ccgttatctt atcttgatcc aaaagcggtt
    27001 tagctgctaa acgaatcgcc tccttccatc ctaatttttg cgaactaacc tgataggttt
    27061 ctttggtaat aagttgttct agcactggta caatttcctt tctatcattt ttttgataaa
    27121 gataattctt taacgccaat cttaattcca attcttgtgt aataattcca tatcttttga
    27181 caatattcag gatttgttca atctcaaaat ctccatactc taaattcgga aaatctttta
    27241 acactagttc tactagttgt attgcttgct cttcagtcat cataaccgaa actagataat
    27301 ttggcttttc tgtctccacc tttatggtag aaaaaaccat atcatagtca ctactagctt
    27361 tcacctgtaa atcatcaatc tttgaggttc ctataaactc aatttgagga aataatgcta
    27421 atagattctc ttttaacatc aatgaagaac taacaccatt aggacaaatg attgctgctt
    27481 tataccattt ttgaggcaaa gtatctgctt tctttaaata acctccgaaa tggataacaa
    27541 aatatgctgt ttcactatca ggtatgggat tgtcaatagc gtccatcaag ggcatcaaag
    27601 aatctttgac taattcaaat aaatcaggat aatgttcttt aacatgcaat acatattcat
    27661 ttgaactagg taggccgaac tttaatctat agtaagccgg tataaggtgg cgacgaagat
    27721 tttctctcaa tccttccctt tgtttaaaat gtaacaaaga aatatcttcc attctactta
    27781 taatagcctc tgttaattga ttaaagtaaa ccggagcaac atctacttca ccttcaaagc
    27841 aacttgataa taaaactgtg atatagcgat aatcatcctc agaaaacacc gtatctataa
    27901 ttcccaaatc aaccactgta tccaataaaa tagtcgttat atcttgaata acaggagata
    27961 ctaatgtctc tgaaagacat actctttcaa catccctttg atacctacac agaatgaata
    28021 ctaaaccgaa aaggtaaact tttaattgat taacaatagg tactagctgt agcttctcat
    28081 aataatcttt aactacctga tcaatcaaat cataagttaa tgaatacccc caactggata
    28141 aaacataatc caaaccccaa atccctatgg aggattccag caactcacta accatttgaa
    28201 aagctaaacg gtgcttattc cactctgaac cgtgtaaagt ataacctttt gctctactgt
    28261 accctagctc caaatcatta tctaacataa tctttcttaa tgattgaata tcagataagg
    28321 ttgtattctt acttactttc aaaaagtctt ggtaatgatt attcgatata aaatctaatc
    28381 ggcaaaaagt gtaaagatag attaaagcta agcgagtcga ctttggtaaa accaattcat
    28441 ccgacttaat aatatctgtc aaagactgct tcgtacgatt tgataaacta tagcgacctt
    28501 gttttttatc cagcactatc cctttattag ctagataagg cactaaataa tctattcctt
    28561 ctttgacttc ctttataggt aagctcacct taacagataa ttcatataat gatagctcac
    28621 aatgatccat caaagtcatc aaaataacta gtgctctata atcaaacatt tctcttcctt
    28681 tctaactaca attatagtgt aaaaattata agaataaaag agtatttgag cacaatataa
    28741 tctcaccttt taaaagaaat tattgggctg aaagttttta gtgattattt tcaactttct
    28801 attgactttt aaaaacaaag tgatatcatt tagatatcaa ataatgggag gtcattctta
    28861 tgactgaaaa actaatcaat tcaaaaccaa atggtgtatt cgcattgatt ctcattgagt
    28921 tgacaatcat acttggtatc tttatattta taatgggtgt tggttcggaa aacatttttg
    28981 gaattattat cggaccttta ctaatcgtaa ttgcaggtct agctcatgct ggtttaaaag
    29041 ttgtcaaacc tcaggaagct ctggttctga cactctttgg taattataca ggtaccatca
    29101 aagaacctgg tttttacttt gtcaatccct tcagcgtagc agtcaaccct gcaaaccaca
    29161 ctcgacttgg acaaagtggt gatgttagca caaaatctcc ttttttagga gctaaatcat
    29221 caaatgacaa tgatgtaaat cttgaaattg gcaagaaaca catttccctc aaagtcatga
    29281 ccttgagcaa ttctcgtcaa aaaatcaatg attgcttagg aaaccctgta gaaatcggta
    29341 tcgcggtaac ttggagagtt gtcgataccg ctaaggcagt cttcaacgtt gataactaca
    29401 aagaatatct ttcattgcaa tgtgatagcg ccctccgtaa tattgtccgc atctatcctt
    29461 acgatgtgtc tcctaatgtg gatactacgg gtgacgggca agcagatgaa ggtagtctcc
    29521 gtggctctag cgaaattgtt gctaaccgta ttcgtgaaga aatccaaagt cgtgttgagg
    29581 atgctggctt ggaaatcctt gaagcacgta tcacttacct agcttatgct ccagaaattg
    29641 ctgccgttat gcttcaacgc caacaagcat ctgccattat tgatgcacgg aagatgattg
    29701 tagatggtgc tgtaggaatg gttgaaatgg cactagaacg gctcaatgaa ggggaattgg
    29761 tagaacttga cgaagaacga aaagctgcca tggtttcaaa tctccttgtc gttctttgtg
    29821 gcaatcatga tgcacaacca attgtcaaca caggaagtct ttactaaaga tggctgaagc
    29881 taaaaaaaag cagatccccc ttcgactctc aacaaagtta tacgctgcac tcgcatcatg
    29941 ggcagaagac gactttcgtt cagtcaatgg gcaaatcgaa tatctcctca cagagtgtgt
    30001 caagcaacgg aaaaaagacg gaaaatacgt atcagaaacc attgacgaac catttgagat
    30061 tgatatttaa catcttctcc tgtctgacaa gtcggacagg agaatttttt catctttttt
    30121 tgtcaagtaa ctttacttta caaaaaaaat gtgttatcct agtatggttg atgaaaatca
    30181 gtagattgaa tcgaatataa atacctaaag gagaaatcaa aatggcagta cctgcacgtc
    30241 gcacttcaaa agcgaagaaa aacaaacgtc gtacacacta caaagtaaca gctccatctg
    30301 taaactttga cgaaactact ggagattact cacgttctca ccgtgtatca cttaaaggat
    30361 actacaaagg acgtaaaatc gctaaagctg catcagctga ataatagaag ggagatacca
    30421 tgcgcgtaaa tattacactt gaacacaaag aatctggtga acgcttgtac cttacttcta
    30481 aaaacaaacg taacactcca gaccgccttc aattgaagaa atactcacca aaacttcgca
    30541 aacacgttgt gtttacagaa gtgaagtaag cattcaatac gaatcaatac agaagaaaaa
    30601 cgcttgatca gcgttttttc tttttgttaa tttcactata ttgcaaggga aatcattcga
    30661 atgactacct ttttcactac cttttttgaa ataagaatac ggattcggac gattaaaagt
    30721 aagagaaact caaatgtaag ttggggttcc ttttttgtat atttttcaaa taacgcctct
    30781 acactatttg tagcaaattc accaactaca gttgtatctt agttaaaata agttagaata
    30841 tgtaagtgag taccagatat accaagacat cgtcaccatc taaggtatat tcaaaataca
    30901 aaagttgacc aactagattt ctgaatatcc ttatatatcc attcttaaaa ttggtttaaa
    30961 tagcgtagtc ttttaaacta gttttgagaa tccaaaaaat cttcctacat atgtaagaag
    31021 attttttagt tcagaatgat tagatttagc taatggatac ctatcctacc cactcaccgt
    31081 tagcattgac tcgatagcca tcgggtgtag tcgtgtttac taataaatct cctgaattat
    31141 aggtatagta ccatttacca gaaactgtaa accaaccagt agccattgaa cctgattcat
    31201 ttaagtaata cca
//
LOCUS       DBEJAU010000025        30329 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC323 isolate 683620
            SAMN38261939-rid24807223.denovo.025, whole genome shotgun sequence.
ACCESSION   DBEJAU010000025 DBEJAU010000000
VERSION     DBEJAU010000025.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261939
            Sequence Read Archive: SRR26833919
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 30329)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 30329)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576303.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576303.1
            Genome Coverage       :: 154x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/19/2025 01:05:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,121
            CDSs (total)                      :: 2,078
            Genes (coding)                    :: 1,943
            CDSs (with protein)               :: 1,943
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 36
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 72 of 135
            Pseudo Genes (incomplete)         :: 63 of 135
            Pseudo Genes (internal stop)      :: 51 of 135
            Pseudo Genes (multiple problems)  :: 46 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..30329
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261939-rid24807223.denovo.025"
                     /strain="GPSC323"
                     /isolate="683620"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            189..392
                     /locus_tag="ACL29Z_001153"
     CDS             189..392
                     /locus_tag="ACL29Z_001153"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001846447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0069472.1"
                     /translation="MPKWSNPDYVNELDPKIVDMLVEFHKSQGTLETPEAQAEIAQKR
                     EEIEQRRAELEDKKQELLNRLNK"
     gene            complement(479..1066)
                     /locus_tag="ACL29Z_001154"
     CDS             complement(479..1066)
                     /locus_tag="ACL29Z_001154"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001808792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0069473.1"
                     /translation="MFVFADDSLSANSKVVSGEAQFENGSSVRFGDTQVNILSDEVLE
                     VVNPDGSVDTIERRADGVYINGAFYMAYQKNEIDLNISFRSYDPNVWNYVNTIHGNKQ
                     ANTFANFMTGAGISYMIGRIGALLGGPWGAIIGGAYFGIQAYQSYLDSQSPYPYYITS
                     TYIHVAQRKWKFITEYYRNSNYTGYVKTVTTYVNF"
     gene            1220..1411
                     /locus_tag="ACL29Z_001155"
     CDS             1220..1411
                     /locus_tag="ACL29Z_001155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000930580.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0069474.1"
                     /translation="MLNAKILYIFLCLIVIETTGLLLLKRGLEMGYLDTEAIILAVFS
                     FAFYNLCSFAWVCSTIKKQ"
     gene            2180..3439
                     /gene="ltrA"
                     /locus_tag="ACL29Z_001156"
     CDS             2180..3439
                     /gene="ltrA"
                     /locus_tag="ACL29Z_001156"
                     /EC_number="2.7.7.49"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000040325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003964 - RNA-directed DNA polymerase
                     activity [Evidence IEA];
                     GO_process: GO:0000373 - Group II intron splicing
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="group II intron reverse transcriptase/maturase"
                     /protein_id="HGR0069475.1"
                     /translation="MSKLLDKILSRENMLEAYNQVKSNKGSAGIDGMTIEEMDNYLRQ
                     NWRLTKELIKQRKYKPQPVLKVEIPKPDGGIRQLGIPTVMDRMIQQAIVQVMSPICEP
                     HFSDTSYGFRPNRSCEKAIMKLLEYLNDGYEWIVDIDLEKFFDTVPQDRLMSLVHNII
                     EDGDTESLIRKYLHSGVIINGQRYKTLVGTPQGGNLSPLLSNIMLNELDKELEKRGLR
                     FVRYADDCVITVGSEAASKRVMYSVSRFIEKRLGLKVNMTKTKITRPRELKYLGFGFW
                     KSSDGWKSRPHQDSVRRFKFKLKKLTQRKWSIEQLNLSIRGWINYFSLGNMKSIVASI
                     DERLRTRLRVIIWKQWKKKSRRLWGLLKLGVPKWIADKVSGWGDHYQLVAQKSVLKRA
                     ISKPVLEKRGLVSCLDYYLERHALKVS"
     gene            3891..5068
                     /locus_tag="ACL29Z_001157"
                     /pseudo
     CDS             3891..5068
                     /locus_tag="ACL29Z_001157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000071468.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ryptide export MFS transporter"
     gene            5382..5513
                     /locus_tag="ACL29Z_001158"
     CDS             5382..5513
                     /locus_tag="ACL29Z_001158"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000813667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="teichoic acid D-Ala incorporation-associated
                     protein DltX"
                     /protein_id="HGR0069476.1"
                     /translation="MKQRKELYLFLGRTALYFLIFLGLLYFFSYLGQGQGSFIYNEF"
     gene            5534..7084
                     /gene="dltA"
                     /locus_tag="ACL29Z_001159"
     CDS             5534..7084
                     /gene="dltA"
                     /locus_tag="ACL29Z_001159"
                     /EC_number="6.1.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012972622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0047473 - D-alanine [D-alanyl carrier
                     protein] ligase activity [Evidence IEA];
                     GO_process: GO:0019350 - teichoic acid biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--poly(phosphoribitol) ligase subunit
                     DltA"
                     /protein_id="HGR0069477.1"
                     /translation="MSNKPIADMIETIEHFAQTQPSYPVYNVLGQEHTYGDLKADSDS
                     LAAVIDQLGLPEKSPVVVFGGQEYEMLATFVALTKSGHAYIPIDSHSALERVSAILEV
                     AEPSLIIAISAFPLEQVSTPMINLAQVQEAFAQGNNYEITHPVKGDDNYYIIFTSGTT
                     GKPKGVQISHDNLLSFTNWMITDKEFATPSRPQMLAQPPYSFDLSVMYWAPTLALGGT
                     LFTLPSVITQDFKQLFAAIFSLPIAIWTSTPSFADMAMLSEYFNSEKMPGITHFYFDG
                     EELTVKTAQKLRERFPNARIINAYGPTEATVALSAVAVTDEMLATLKRLPIGYTKADS
                     PTFIIDEEGNKLPNGEQGEIIVSGPAVSKGYMNNPEKTAEAFFEFEGLPAYHTGDVGT
                     MTDEGLLLYGGRMDFQIKFNGYRIELEDVSQNLNKSRFIESAVAVPRYNKDHKVQNLL
                     AYVILKDSVREQFERDIDITKAIKEDLTDIMMSYMMPSKFLYRDSLPLTPNGKIDIKG
                     LINEVNKR"
     gene            7081..8325
                     /gene="dltB"
                     /locus_tag="ACL29Z_001160"
     CDS             7081..8325
                     /gene="dltB"
                     /locus_tag="ACL29Z_001160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000969717.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016746 - acyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0070395 - lipoteichoic acid biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-lipoteichoic acid biosynthesis protein
                     DltB"
                     /protein_id="HGR0069478.1"
                     /translation="MMEFFQQLPHLEPYGNPQYFVYVIAATLPIFIGLFFKKRFAWYE
                     VLVSLFFIVTMLVGGKTNQLAALGIYLCWEILLLLFYKHYRKSKDGKWVFYLVSFLSL
                     LPIIFVKVQPAINGTQSLLGFLGISYLTFRSVGIIIELRDGVIKDFTLWEFLRFLLFM
                     PTFSSGPIDRFKRFNENYQAIPERDELMDMLDESVRYIMWGFLYKFILAHVLGETLLP
                     PLKNLALQSGGFFNLYALAVMYTFGLELFFDFAGYSMFALAISNLMGIRSPINFNKPF
                     LSRDLKEFWNRWHMSLSFWFRDFVFMRMVMVLTRKKVFKNRNVTSSMAYIVNMLIMGF
                     WHGVTWYYIAYGLFHGLGLVINDAWVRKKKTLNKERKKAGKAALPENRWIQLLGMVVT
                     FHVVMLSFLIFSGFLNNLWFKK"
     gene            8339..8578
                     /gene="dltC"
                     /locus_tag="ACL29Z_001161"
     CDS             8339..8578
                     /gene="dltC"
                     /locus_tag="ACL29Z_001161"
                     /EC_number="6.1.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005591431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0036370 - D-alanyl carrier activity
                     [Evidence IEA];
                     GO_process: GO:0019350 - teichoic acid biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--poly(phosphoribitol) ligase subunit
                     DltC"
                     /protein_id="HGR0069479.1"
                     /translation="MDIKSEVIEIIDELFMEDVSDMMDEDLFDAGVLDSMGTVELIVE
                     IENRFDIRVPVTEFGRDDWNTANKIIAGIVELQNA"
     gene            8571..9839
                     /gene="dltD"
                     /locus_tag="ACL29Z_001162"
     CDS             8571..9839
                     /gene="dltD"
                     /locus_tag="ACL29Z_001162"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000919885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0070394 - lipoteichoic acid metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-lipoteichoic acid biosynthesis protein
                     DltD"
                     /protein_id="HGR0069480.1"
                     /translation="MLKRLWMIFGPVLIAGLLVFLLIFFYPTEMHHNLGAEKRSAVAT
                     TIDSFKERSQKVRALSDPNVRFVPFFGSSEWLRFDGAHPAVLAEKYNRSYRPYLLGQG
                     GAASLNQYFGMQQMLPQLENKQVVYVISPQWFSKNGYDPAAFQQYFNGDQLTSFLKHQ
                     SGDQASQYAATRLLQQFPNVAMKDLVQKLASKGELSTADNEMIELLARFNERQASFFG
                     QFSVRGYVNYDKHVAKYLKILPDQFSYQAIEDVVKADAEKNTSNNEMGMENYFYNEQI
                     KKDLKKLKDSQKSFTYLKSPEYNDLQLVLTQFSKSKVNPIFIIPPVNKKWMDYAGLRE
                     DMYQQTVQKIRYQLESQGFTNIADFSKDGGEPFFMKDTIHLGWLGWLAFDKAVDPFLS
                     NPTPAPTYHLNERFFSKDWATYDGDVKEFQ"
     gene            9994..10434
                     /gene="adcR"
                     /locus_tag="ACL29Z_001163"
     CDS             9994..10434
                     /gene="adcR"
                     /locus_tag="ACL29Z_001163"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001249319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-dependent transcriptional regulator AdcR"
                     /protein_id="HGR0069481.1"
                     /translation="MRQLAKDINAFLNEVILQAENQHEILIGHCTSEVALTNTQEHIL
                     MLLSEESLTNSELARRLNVSQAAVTKAIKSLVKEGMLETSKDSKDARVIFYQLTDLAR
                     PIAEEHHHHHEHTLLTYEQVATQFTPNEQKVIQRFLTALVGEIK"
     gene            10434..11138
                     /locus_tag="ACL29Z_001164"
     CDS             10434..11138
                     /locus_tag="ACL29Z_001164"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001269494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter ATP-binding protein"
                     /protein_id="HGR0069482.1"
                     /translation="MRYITVEDLSFYYDKEPVLEHINYSVDSGEFVTLTGENGAAKTT
                     LIKASLGILQPRIGKVAISKTNTQGKKLRIAYLPQQIASFNAGFPSTVYEFVKSGRYP
                     RKGWFRRLNAHDEEHIKASLDSVGMWEHRDKRLGSLSGGQKQRAVIARMFASDPDVFI
                     LDEPTTGMDAGSKNEFYELMHHSAHHHGKAVLMITHDPEEVKDYADRNIHLVRNQDSP
                     WRCFNVHENGQEVSHA"
     gene            11131..11937
                     /locus_tag="ACL29Z_001165"
     CDS             11131..11937
                     /locus_tag="ACL29Z_001165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0030001 - metal ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter permease"
                     /protein_id="HGR0069483.1"
                     /translation="MLSLLSYDFIQRAFLAVIAMSLFSPVLGTFLILRRQSLMSDTLS
                     HVSLSGVAFGLVLGISPTVSTIAIVLIAAVFLEYLRTVYKSFMEIGTAILMSTGLAVS
                     LIVMSKGKSSSSMSLDQYLFGSIVTISEEQVISLFVIAAVVLILTFLFLRPMYILTFD
                     EDTAFVDGLPVRTMSILFNMVTGVAIALMIPAAGALLVSTIMVLPASIALRLGKNFKS
                     VMLLASAIGFLGMVAGLYISYYAETPASASITIIFVTVFILISLVRRFIK"
     gene            11947..13452
                     /gene="adcA"
                     /locus_tag="ACL29Z_001166"
     CDS             11947..13452
                     /gene="adcA"
                     /locus_tag="ACL29Z_001166"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000724057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ABC transporter substrate-binding
                     lipoprotein AdcA"
                     /protein_id="HGR0069484.1"
                     /translation="MKKISLLLASLCALFLVACSNQKQADGKLNIVTTFYPVYEFTKQ
                     VAGDTANVELLIGAGTEPHEYEPSAKAVTKIQDADTFVYENENMETWVPKLLDTLDKK
                     KVKTIKATGDMLLLPGGEEEEGDHDHGEEGHHHEFDPHVWLSPVRAIKLVEHIRDSLS
                     ADYPDKKETFEKNAAAYIEKLQALDKAYVEGLSQAKQKSFVTQHAAFNYLALDYGLKQ
                     VAISGLSPDAEPSAARLAELTEYVKKNKIAYIYFEENASQALANTLSKEAGVKTDVLN
                     PLESLTEEDTKAGENYISIMEKNLKALKQTTDQEGPAIEPEKAEDTKTVQNGYFEDAA
                     VKDRTLSDYAGNWQSVYPFLEDGTFDQVFDYKAKLTGKMTQAEYKAYYTKGYQTDVTK
                     INITDNTMEFVQGGQSKKYTYKYVGKKILTYKKGNRGVRFLFEATDADAGQFKYVQFS
                     DHNIAPVKAEHFHIFFGGTSQEALFEEMDNWPTYYPDNLSGQEIAQEMLAH"
     gene            complement(14580..15353)
                     /locus_tag="ACL29Z_001167"
     CDS             complement(14580..15353)
                     /locus_tag="ACL29Z_001167"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000588554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR family DNA-binding transcription
                     regulator"
                     /protein_id="HGR0069485.1"
                     /translation="MIKDERVLELIEIIKKKKRIAVKELAEITFSSTSTLRRDLIFLE
                     NQGLIKRKHGYVTLSSMNTIELSHQIREGESTRQKRLIASLAKDFIRSGMCIYLDSST
                     TVYELCPYLSELDNLIIFTNGLHTAQTLSETVKDSSKIFITSGEVKHQSCSVVNYDKE
                     NSLLDHFNIDLAFCSARGIDDQYVYEASLSQAISKKNIIDKAHETILLIDSSKFYKTG
                     FFKINPLSKYTTFISDTVPDQKLLDAVELFDGEWVSDIQ"
     gene            15529..16932
                     /locus_tag="ACL29Z_001168"
     CDS             15529..16932
                     /locus_tag="ACL29Z_001168"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000388528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0019200 - carbohydrate kinase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="rhamnulokinase family protein"
                     /protein_id="HGR0069486.1"
                     /translation="MEAVLAIDLGATSGRAIVGYLSENKLVMEEINRFSNLPIRVKGH
                     LSWDIDFLLAKILESIRLANTSYKILSIGIDTWGVDFGLIDNEGKLLSQPVHYRDERT
                     KGVLKEISEMTELEKLYSETGNQIMEINTLFQLFKARQESPDSFYKTNKILLMPDLFN
                     YLLTGKFATEKSIASTTQLFDPRSQNWNQNILKLFELDSSLLPEIVSEGNVLGRIKKE
                     YGLGDIPVVNVCSHDTASAIVSVPKTEGSLFISSGTWSLVGVELTSPILTTESFSYGF
                     TNEVGKDGVITFLKNCTGLWIIEELRRSFERRGKAYSFDDIRTMVEKEKENLPLIDTE
                     STEFATESDMHKTLTEYLAYHHETREWTDGQLFKIVYESLAETYRKAIELLEELTHKV
                     YKRIYVIGGGARASYFNQMIADRTGKEVLTGLTEGTAVGNIVVQLIAMGQLKGMEEAH
                     HVIEEFLQLESYYSQKN"
     gene            17047..17685
                     /locus_tag="ACL29Z_001169"
     CDS             17047..17685
                     /locus_tag="ACL29Z_001169"
                     /EC_number="4.1.2.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001286141.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-fuculose-phosphate aldolase"
                     /protein_id="HGR0069487.1"
                     /translation="MSDVKQELIKYGKKLVETDLTKGTGGNLSVFDREKQLMAITPSG
                     IDFFEIKESDIVVMDINGNVVEGERLPSSEWYMHLIQYQTRDDIDAIIHAHTTYATVL
                     ACLREPLPASHYMIAVAGKDVRVAEYATYGTKELAVNAAKAMEGRRAVLLANHGILAG
                     AQNLLNAFNIVEEVEYCAKIYCLAKNFGEPVVLPDEEMDLMAEKFKTYGQRK"
     gene            17697..18137
                     /locus_tag="ACL29Z_001170"
     CDS             17697..18137
                     /locus_tag="ACL29Z_001170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000912112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RbsD/FucU family protein"
                     /protein_id="HGR0069488.1"
                     /translation="MLKHIPKNISPDLLKTLMEMGHGDEIVLADANYPSASCANKLIR
                     CDGVNIPELLDSILYLMPLDSYVDSSIQFMNVVSGDDIPKIWGTYRQMIEGHGTDLKT
                     ITYLRREDFYERSKKAYAIVATGETSLYANIILKKGVVVERENV"
     gene            18130..18561
                     /locus_tag="ACL29Z_001171"
     CDS             18130..18561
                     /locus_tag="ACL29Z_001171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000483177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HGR0069489.1"
                     /translation="MFNRGILVASHGNFASGALMTAEMFVGETTNDRVRTLGLMPGEN
                     IVEFEHYFKNQVDELLDSNQEVIVLTDLIGGSPNNVALSRFLNFDSVDIVTGFNIPLL
                     VELISSYDSKINLEEIVHNAQNSLFNVKQQLNVEEEEDLCL"
     gene            18552..19022
                     /locus_tag="ACL29Z_001172"
     CDS             18552..19022
                     /locus_tag="ACL29Z_001172"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000020992.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HGR0069490.1"
                     /translation="MSIEFVRIDDRLVHGQVVTTWLKKYDIEQVIIVNDRISEDKTRQ
                     SILKISAPVGLKIVFFSVKRFVEVLNSVPIKKRTMLIYTNPKDVYDSIEGNLKLEYLN
                     VGQMSKTEENEKVTGGVALGEEDKYYFKKIVDKGTRVEIQMVPNDKVTMLEKFL"
     gene            19047..19820
                     /locus_tag="ACL29Z_001173"
     CDS             19047..19820
                     /locus_tag="ACL29Z_001173"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000899624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS
                     mannose/fructose/sorbose/N-acetylgalactosamine transporter
                     subunit IIC"
                     /protein_id="HGR0069491.1"
                     /translation="MLFTQALLVTLVGIIATIDYNGPLFMIHRPLVTSAMVGLVLGDF
                     TQGVLIGSALELTWLGVTGIGGYTPPDTISGAIIGTAFGILSGQGETAGIAIAVPIAV
                     ATQQLDVLAKTLDVYFVKKADNDAKNGDYSKIGFYHYSSLVLITLFKIVPIFLAIMLG
                     GEYVADLFAKVPPIVMQGLNSAGALLPSIGFGMLLNMMLKKNMWVFLLIGFICSVYGG
                     MSTIGISLVGIAVAYFYDMIGSKPQETTSSSDVEEDLDL"
     gene            19817..20617
                     /locus_tag="ACL29Z_001174"
     CDS             19817..20617
                     /locus_tag="ACL29Z_001174"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002935197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HGR0069492.1"
                     /translation="MMNNKVTKVELKKVFKRSFMYGSSWNYERMQNLGFLYTILPVLK
                     KLYPDKDSASPAMKRHLEFFNTHQTAAPFILGVTSAMEEQEGNEGAASITGIKVGLMG
                     PLAGLGDSLFWLTLVPICFSIGASYSKDGGALGIFIALILFNIINIPVKYFGLKYGYT
                     KGSSLIQENNTKGTLNRVTSMATALGLVLVGGLIPSMVGINFGLEFKQGELVISVQEM
                     ITKLIPGFIPMALTLLMCKLIRKGKNPVVLIFSVMAIGVILVVLGILK"
     gene            20676..22970
                     /locus_tag="ACL29Z_001175"
     CDS             20676..22970
                     /locus_tag="ACL29Z_001175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000780629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 95 protein"
                     /protein_id="HGR0069493.1"
                     /translation="MKLWYKKAAANWNEALPIGNGHLGGMIYGSATKECIQLNDETIW
                     YRGKSDRNNPDSLLHLKKIREYLLDGEIQKAEELIKLTVFATPRDQSHYELLGELYIE
                     HIDIQSCALSLYERELDLDTAISNVVFEPNSCNLQIKREYFTSFNKNILCCRIVSSVQ
                     NTLNLNINLGRNKRFNDEVSKLDSSTILMSASAGGRKGVQFKVVCHSKVTDGEVSVLG
                     ETIVIRNATEVFLYLKSMTDYWGNIDISSLQGEFSSIDYFTEKDEHVKKYQEQFNRVD
                     FKLDYSKGCLSIPTNLLLENTKKYSNYLTNLLFHYGRYLLISSSQPNGLPANLQGIWC
                     DELNPIWGSKYTININTQMNYWMVGPCDLPEVEYPLFDMLERMREPGRLTAKKMYGAR
                     GFTAHHNTDGFGDTAPQSHAMGAAIWVLTIPWLCTHIWEHYLYFQDERILTEHFEMIK
                     EAFLFFEDYLFEVDGYLMTGPSVSPENKYRLKNGIEGNACLSSTIDNQILRYFCDSCI
                     GIAKQLGDNSDFISRVKELKKKLPRTKIGSNGQIQEWLEDYEEVEPGHRHISPLFGLY
                     PYNEIDIHKTPELAEAAKITINRRLSNANFLSSQDREQAINNWLVSGLHASTQTGWSA
                     AWLIHFFARLYQGEPAYNQINGLLNNATLGNLFLDHPPFQIDGNLGLVSGICELLVQS
                     HHNWLSLIPALPSAWSEGEVKGFRVRGGYKVSFAWKNGDITFLKLEGGNKDQKVRVRI
                     YGKNTDVQNIELVFNSEKIIELNF"
     gene            22980..26096
                     /locus_tag="ACL29Z_001176"
     CDS             22980..26096
                     /locus_tag="ACL29Z_001176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001031112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl hydrolase family 98 C-terminal
                     domain-containing protein"
                     /protein_id="HGR0069494.1"
                     /translation="MNKEKIKRKLITILFVCIGMLCFGLLAGVKADNRVQMRTTINNE
                     SPLLLSPLYGNDNGNGLWWGNTLKGAWEAIPEDVKPYAAIELHPAKVCKPTSCIPRDT
                     KELREWYVKMLEEAQSLNIPVFLVIMSAGERNTVPPEWLDEQFQKYSVLKGVLNIENY
                     WIYNNQLAPHSAKYLEVCAKYGAHFIWHDHEKWFWETIMNDPTFFEASQKYHKNLVLA
                     TKNTPIRDDAGTDSIVSGFWLSGLCDNWGSSTDTWKWWEKHYTNTFETGRARDMRSYA
                     SEPESMIAMEMMNVYTGGGTVYNFECAAYTFMTNDVPTPAFTKGIIPFFRHAIQNPAP
                     SKEEVINRTKAVFWNGEGRISSLNGFYQGLYSNDETMPLYNNGRYHILPVIHEKIDKE
                     KISSIFPNAKILTKNSEELSSKVNYLNSLYPKLYEGDGYAQRVGNSWYIYNSNANINK
                     NQQVMLPMYTNNTKSLSLDLTPHTYAVVKENPNNLHILLNNYRTDKTAMWALSGNFDA
                     SKSWKKEELELANWISKNYSINPVDNDFRTTTLTLKGHTGHKPQINISGDKNHYTYTE
                     NWDENTHVYTITVNHNGMVEMSINTEGTGPVPFPTPDKFNDGNLNIAYAKPTTQSSVD
                     YNGDPNRAVDGNRNGNFNSGSVTHTRADNPSWWEVDLKKMDKVGLVKIYNRTDAETQR
                     LSNFDVILYDNNRNEVAKKHVNNLSGESVSLDFKEKGARYIKVKLLTSGVPLSLAEVE
                     VFRESDGKQSEEDIDKITEDKVVSTNKVATQSSTNYEGVAALAVDGNKDGDYGHHSVT
                     HTKADSNAWWQVDLGEEFTVSKVDIYNRTDAEPQRLSNFDVIFLSSSGEEVFRRHFDK
                     VVDGLLSLKVPSVGAKLVKIELKSAAIPLSLAEVEVYGSKRTPKKLSNIALTKETRQS
                     STDYNGFSRLAVDGNKNGDYGHHSVTHTKGDSPSWWEIDLAQTEELEKLIIYNRTDAE
                     IQRLSNFDIIIYDSNNHEVFKQHIDSLESNNLSIDLKGLKGKKVRISLRNAGIPLSLA
                     EVEVYTYK"
     gene            26179..27945
                     /locus_tag="ACL29Z_001177"
     CDS             26179..27945
                     /locus_tag="ACL29Z_001177"
                     /EC_number="5.3.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002935191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008736 - L-fucose isomerase activity
                     [Evidence IEA];
                     GO_function: GO:0030145 - manganese ion binding [Evidence
                     IEA];
                     GO_process: GO:0005996 - monosaccharide metabolic process
                     [Evidence IEA];
                     GO_process: GO:0019317 - fucose catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="L-fucose isomerase"
                     /protein_id="HGR0069495.1"
                     /translation="MIQHPRIGIRPTIDGRRQGVRESLEVQTMNMAKSVADLISSTLK
                     YPDGEPVECVISPSTIGRVPEAAASHELFKKSNVCATITVTPCWCYGSETMDMSPDIP
                     HAIWGFNGTERPGAVYLAAVLASHAQKGIPAFGIYGRDVQEANDTAIPEDVKEKLLRY
                     ARAALATGLMRDTAYLSMGSVSMGIGGSIVNPDFFQEYLGMRNESVDMTEFTRRMDRG
                     IYDPEEFERAMVWVKEHIKEGVDRNREDLILSKEEKEKQWEFVIKMFMIGRDLMVGNP
                     RLAELGFEEEAVGHHALVAGFQGQRQWTDHFPNGDFMETFLNTQFDWNGIRKPFVFAT
                     ENDSLNGVSMLFNYLLTNTPQIFADVRTYWSPEAVERVTGHTLEGRAAAGFLHLINSG
                     SCTLDGTGQATRDGKPVMKPFWELEESEVQAMLENTDFPPANREYFRGGGFSTRFLTK
                     GDMPVTMVRLNLLKGVGPVLQIAEGYTLELPEDVHHTLDNRTDPGWPTTWFAPRLTGK
                     GAFKSVYDVMNNWGANHGAITYGHIGADLITLASMLRIPVNMHNVPEEDIFRPKNWSL
                     FGTEDLESADYRACQLLGPLHK"
     gene            28091..29242
                     /locus_tag="ACL29Z_001178"
     CDS             28091..29242
                     /locus_tag="ACL29Z_001178"
                     /EC_number="1.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862055.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016616 - oxidoreductase activity, acting
                     on the CH-OH group of donors, NAD or NADP as acceptor
                     [Evidence IEA];
                     GO_function: GO:0030554 - adenyl nucleotide binding
                     [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="iron-containing alcohol dehydrogenase"
                     /protein_id="HGR0069496.1"
                     /translation="MAIFYVPAVNLIGKGVVNEVGPYIKELGYKKALLVTDKYIEGSD
                     ILPKVLKPLDTEGIEYVIFSDVEPNPTCKNVTDGVAALQEHGCDFIISLGGGSPQDAA
                     SCISIMATNGGKPQDYEGLHKSAKKGLPVVAINTTAGTSAEITINYVITDEERKVKMV
                     MVDKNSLALISVNDPELMLSKPQALTAATGMDALTHAVEALVTPGAYDVTKKLSIGAI
                     ELIKEYLPRAVANGHDIEAREGMVNAIFLGGMSFNNAGLGYVHSMAHQLGAVYNLPHG
                     VCCAMLLPVIERENAKRVPEAFRNVAKALGLHVEGKSDQECADYAIAEIEKLSETVGI
                     PKKLTELGIEEKDFDFEYLSKNALIDACAPGNPFMPTLEETIAFYKELF"
     gene            29386..30270
                     /locus_tag="ACL29Z_001179"
     CDS             29386..30270
                     /locus_tag="ACL29Z_001179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001838996.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPFH domain-containing protein"
                     /protein_id="HGR0069497.1"
                     /translation="MIFLIVCVLLLVIVTLSTVYVVRQQSVAIIERFGKYQKVANSGI
                     HIRLPFGIDSIAARIQLRLLQSDIVVETKTKDNVFVMMNVATQYRVNEQSVTDAYYKL
                     IRPESQIKSYIEDALRSSVPKLTLDELFEKKDEIALEVQHQVAEEMTTYGYIIVKTLI
                     TKVEPDAEVKQSMNEINAAQRKRVAAQELAEADKIKIVTAAEAEAEKDRLHGVGIAQQ
                     RKAIVDGLAESITELKEANVGMTEEQIMSILLTNQYLDTLNTFASKGNQTIFLPNTPN
                     GVDDIRTQILSALRAEKK"
BASE COUNT         9577 a         5050 c         6445 g         9257 t
ORIGIN      
        1 tagaaaacaa ttatgttgat agagcttggg caagagccca atttcagcaa aaaatgaagt
       61 aaatcttctc ataataaaac gcatcatatc aagcacgaaa attccacgag gtcaactaca
      121 gtcagaaagc tgaacaacaa gccaaaacgc ccaaaaaagg cggcaaaaag caagcacctg
      181 caagcaacgt gccgaaatgg tccaatcctg attatgtcaa cgaattagac ccaaaaatcg
      241 ttgatatgct agtagaattt cacaagtcac aaggcacttt ggaaactccc gaggcgcaag
      301 cagaaatcgc ccaaaaacgt gaagaaatcg agcaaaggag agctgagctt gaggataaaa
      361 aacaagagct tttgaaccgc ttgaacaaat agagtttcgc aagtattatg cttacaaatt
      421 acttgagcaa ttaactaaaa tataaaccct gcctttatat ctaggcaggg tttatatttt
      481 agaaattcac gtaggttgtt acggttttta catacccagt atagtttgag tttctatagt
      541 attcagtgat aaacttccat tttctttgag caacatggat ataagtactt gttatgtagt
      601 atggatatgg gctttgtgaa tccaagtaag actgataagc ttgtatacca aaatatgctc
      661 caccaattat tgcaccccat ggacccccca ataaagcacc tatcctacca atcatataac
      721 tgattccagc accagtcatg aagttagcga atgtgttagc ttgtttattc ccatgtattg
      781 tgttgacgta attccaaaca ttaggatcgt atgatctaaa agatatattt aggtcgattt
      841 cattcttttg ataagccata taaaatgccc cattgatata gacgccgtca gcacgtcgtt
      901 caatagtgtc tacacttcca tctggattga caacctcaag aacttcatcg cttaaaatat
      961 ttacttgcgt atctccgaac cgcactgatg agccattctc aaactgagcc tcaccagata
     1021 caactttaga gtttgccgat aagctatcat cagcaaaaac aaacaagcga cggggaaatg
     1081 ctagacatac agaaaacaga cataactagc aaacacatgc atttaaacat cttagacata
     1141 acggaaactc ctttgtattt ttgatttttt tcaactttta ttatacaata aaaccaaata
     1201 aaaagaaagc ggtaacaata tgcttaatgc gaaaatttta tatatatttt tatgtttgat
     1261 cgttatcgaa actacaggct tgttgttgtt gaaaagaggt ctcgaaatgg gttatttaga
     1321 cacagaagct attatcctcg cagttttttc atttgctttt tacaacctat gttcattcgc
     1381 ttgggtctgc tctacaataa aaaaacaata aaaaataaat agacgtattt tcaaaaaaaa
     1441 aaaaaaatgc atatttatat tagcaaaacg acgatttaaa tcgtcgtttt tttgtagtac
     1501 gacgggcatg tcgtatatct gaggtgtaag tcctcggtgg gcacctgcta ccggtgaacc
     1561 caatagcgat tcccaagcct gactatcgtg aggtagcagg gagaggaagg gatagcgaaa
     1621 tcgtggctct acgaacagga acgtgatagt aaggcgtata tagcggataa ggaggcttca
     1681 aactctaaag tccaaaaagg tagtcgtaac ctatatgtgt aaatcacgag agtaattgaa
     1741 ttcggactaa ggtttgtgtg aaaaagataa atctttctag agtctaaaga ctctgcgtca
     1801 gatttcctat tttcactgta accttttaac gtcctcatat cttgtataaa cgaggaaaga
     1861 tgtacgactt atcccgtgag gtttcatgag cgctgaaagc gtagtaacaa cgaatcatga
     1921 gaagtcagcc gaacccatag tagtgaggaa acttctgtag tggaagtgga gcgaaggggt
     1981 gaatactcaa acagtctggg gagagactgt ttgaggtctg tcgctagaaa gagaaaacga
     2041 cagatcgaag taatcctact tcacttgtgt ctgtaaaatg agtggtctga tagaactgga
     2101 ctttgacacg taatgactag atgaaggttc accaatataa gatgtccctc aggcaccaaa
     2161 acaagaaagg aatacgcaca tgtcaaaact gctagataag atattatcac gcgaaaatat
     2221 gctggaagcc tacaatcaag taaaatccaa taaaggctca gctgggattg atggaatgac
     2281 tatcgaagag atggataatt atctcagaca aaactggcgc ttgactaagg aactgataaa
     2341 acagagaaaa tataagcctc aaccagttct taaagttgag atacctaaac cagacggagg
     2401 catccgtcaa ctaggaattc caacagttat ggatagaatg attcaacagg ccattgtcca
     2461 agtcatgagc cccatttgtg aaccccattt ctcagatacg agttatggtt tcagaccaaa
     2521 taggtcatgt gaaaaagcca tcatgaagct cttagaatac ttaaatgacg gctatgagtg
     2581 gatagtggat atagacctag agaaattttt cgatacagtt cctcaagata gattgatgtc
     2641 cttagtacat aacattatcg aagacggaga tacggaatcc ttgattcgta agtatcttca
     2701 ttcaggtgtt atcattaatg gtcaacgtta taaaacacta gttggtacac cacagggagg
     2761 aaatttatct cctctcttat ccaatatcat gcttaatgaa ttggacaagg aattagaaaa
     2821 gaggggactt cgatttgtgc gctacgcaga tgattgtgtg attacggtcg gaagcgaggc
     2881 agcctctaag cgtgtgatgt attcagtcag tcgttttatt gagaaacggc taggtttgaa
     2941 agtaaacatg accaagacta agattaccag accaagagag ttgaaatatc taggttttgg
     3001 gttctggaaa tcatcagatg gttggaaaag ccgtccacat caagatagtg ttcggagatt
     3061 taagtttaaa ttgaagaaac taacacagag gaaatggagt attgagcaac tgaatttgtc
     3121 tattcgagga tggataaact atttctcatt gggaaatatg aaaagtatag tcgccagcat
     3181 agatgagcgc ttgcgtactc gcctacgagt gattatctgg aagcaatgga agaagaaatc
     3241 gagacgatta tggggattgc ttaagttagg ggttcctaaa tggatagcag ataaggtatc
     3301 tggctggggc gaccattatc aattagtagc tcagaagtcg gtacttaaac gtgctatatc
     3361 aaaaccagtc ctggaaaaac gtggactggt ttcgtgtttg gattattacc ttgaacgaca
     3421 tgcgttaaaa gttagttgaa ccgctgtatg ccgaacggca cgtacggtgg tgtgagaggg
     3481 gctagagatt atcccctact cgattaactc ccctgaaatt tattttaatt atgcaaattt
     3541 cacgtatttt tgatgctgag acgacgatcc tgggaacttt tcagatattt ttttgactat
     3601 ctaaatctat cattagaaaa gcttagagcg ccaaaggatt tgagcgtttt tctgattttt
     3661 aagacttttt ccagtctctt tttcgattga agatgtaatt attctactaa ctaacttctt
     3721 agtactagcc aacaacgata atcataattc ctcctaaaat taggaataat aaaggcaata
     3781 gtttttgttt tttcatgtaa aaaacctcac ttttgttttc tgctatttta tgctaaaata
     3841 ttaaaaatca aatttaattc caaagtttgt aactaaaggg ggagcgctac atgtctaatt
     3901 catttgtcaa gttgttagtc tctcaattat ttgcaaattt agcagatatt ttctttagag
     3961 taacaatcat tgctaacata tacattattt caaaatcagt aattgccaca tcactagttc
     4021 ctatcttaat aggaatatcc tcttttgttg cgagtctttt agttccgttg gttactaaaa
     4081 ggttagcgct aaatagggtt ttatctttat ctcaatttgg aaagactata ttattggcga
     4141 tactggtagg aatgtttacc gtaatgcaat ccgtagcgcc tttggtgacc tatctatttg
     4201 ttgttgcaat ttccatacta gatggttttg cagcacccgt ttcctatgct attgtgccac
     4261 gctatgcgac cgatttgggt aaggctaatt cagccttatc aatgactggt gaagctgttc
     4321 aattgatagg ttggggatta ggtggactct tgtttgcaac aattggtctg ttacctacca
     4381 cgtttatcat tttagtcttg tatatcattt ctagctttct gatgttattt cttcctaacg
     4441 ctgaagtgga ggtgttagag tcagaaacta atcttgaaat tttgctcaaa ggttggaagt
     4501 tagttgctag aaatcctaga ttaagacttt tgtatcagca aatttattgg aaattttttc
     4561 aaatacgatt tgggtttctt ccattatact tgtttttgta acggagttat taaataaaac
     4621 ggaaagttac tggggatatt ctaatacagt atactctatt ggtattataa ttagtggctt
     4681 aattgctttt aggctatctg aaaagttcct tgctgctaaa tgggaaagta ttctttttcc
     4741 tcttgtagct atggcaatag tgacactgac tattctatat tttccaaacg cacagatgtt
     4801 tttattattt tcagctttag ttggtatgtt atcgcaacta aaagaagttc ctgaaagtgt
     4861 atttcttcag gaaacagtag aggaaaatca tttagttaat gtctattccg ttcttgaagt
     4921 gatttctaca ttagcatttt cagtatttgt tttgctaatg agctatatta ctgagagttt
     4981 tggtattagc atcagttttt ggctatcagc catttgtctg atgatagaag ctattttaat
     5041 ttatatcaga cgagattatt ttaaatgaga gagtggttaa aaagtcttta aaaatcagaa
     5101 aagcgcatag tatcaggtgt tgaaaaaact tgatattgtg tgttttatta tgggaagatt
     5161 tacttcattg tctcctgaaa tggagttttg aagcaggatc actctatttg aaaatataca
     5221 tagaaaaacc gcataatcct taaaataagc tgaaatctat tggaaacata cggtaaacaa
     5281 ttgaaaagat actatataaa gtggtacaat ggtagaaaaa taagctagta agaatcactc
     5341 ttattttagc gaaaaattac agaaatgaat ggtttttctt gatgaaacag agaaaagaat
     5401 tgtacctctt tcttggtcgg acagccttgt attttcttat ctttctaggg ctgctttact
     5461 tctttagcta tcttggtcag ggtcaaggaa gctttatcta taatgaattt taacttgaag
     5521 gagaagccct attgtgtcaa ataaaccaat agcagatatg attgaaacca ttgagcattt
     5581 tgctcagaca cagcctagct atcctgtcta taatgttttg gggcaggaac acacttatgg
     5641 cgatttaaag gctgattcgg atagtttggc tgcagtcatt gaccaactag gcttgcctga
     5701 aaagtctcct gtggttgttt ttggtggcca agaatatgaa atgttggcaa cctttgtagc
     5761 gctgactaag tcaggtcatg cctacattcc aattgatagc cattcggcct tggagcgagt
     5821 ttcagctatt ttagaagtag cagagccaag cttgattatt gccatttcag cctttccctt
     5881 ggagcaggtt tctacaccaa tgataaatct agctcaggtt caagaagcct ttgcccaagg
     5941 gaacaactat gaaatcacgc atccagtcaa gggagatgat aattactaca ttatctttac
     6001 ttctggtacg actggtaagc ctaagggagt gcagatttca catgataatc tcctcagctt
     6061 tacaaactgg atgattacgg ataaggaatt tgcgacaccg agtcgtccgc aaatgctggc
     6121 acagccacct tattcttttg acttgtctgt catgtattgg gcaccgacct tggcacttgg
     6181 tggtacgctt ttcactcttc cttcagtcat cactcaggac tttaagcaac tctttgcggc
     6241 tatcttttca ttgccaatcg ctatctggac atcaacacca tcctttgcag atatggccat
     6301 gttgtctgaa tacttcaaca gtgaaaaaat gcctggaatc acgcatttct actttgatgg
     6361 tgaagaattg acggtcaaaa cagctcaaaa actgcgcgag cgtttcccaa atgcccgtat
     6421 catcaatgct tacggcccaa cagaagcgac agtagctctg tcagcagttg ccgtgacaga
     6481 cgagatgtta gcgactctca aacgcctacc aatcggctat accaaggctg attctccaac
     6541 ctttatcatt gacgaggaag gaaataaact gccaaatggc gaacagggag aaatcattgt
     6601 ttctgggcca gctgtttcaa aaggttatat gaacaatcct gaaaaaacag cagaagcctt
     6661 ctttgagttt gaaggtctgc cagcctatca cacaggcgat gtgggaacca tgacagatga
     6721 gggcttgctt ctctacggcg gacgcatgga cttccagatt aagttcaacg gttaccgcat
     6781 tgagttagaa gatgtctctc aaaacctcaa caagtctcgc tttatcgaat ctgctgtcgc
     6841 agtaccgcgc tataacaagg accacaaggt acaaaatcta ttggcttatg tcatcttaaa
     6901 agacagtgtt cgtgagcagt ttgagcgaga tatcgatatt accaaggcca tcaaggaaga
     6961 cctgacagac atcatgatgt cctacatgat gccatctaaa ttcctttacc gagacagttt
     7021 gccactgact ccaaatggaa agattgacat caaaggattg attaacgagg tgaataagag
     7081 atgatggagt tttttcaaca gcttcctcat ttagagccat atggcaatcc tcagtatttt
     7141 gtttatgtga ttgctgcaac cttgcccatc tttataggcc tctttttcaa gaaacgcttt
     7201 gcctggtatg aagtgttggt aagtctcttc tttattgtca ccatgttggt gggtggaaag
     7261 accaatcaac tagctgcctt gggtatttac ctttgctggg aaatattgct cctgcttttc
     7321 tacaagcatt atcgaaaaag caaggatggc aagtgggtct tctacttagt tagttttctg
     7381 tccctacttc cgattatctt tgtcaaggtg caaccagcta tcaatggaac gcagtctttg
     7441 cttgggttct tgggaatttc ttacctgacc tttcgttcgg ttgggattat catcgagctg
     7501 agagatggag tgattaagga ttttaccctc tgggaattcc tccgtttcct tctcttcatg
     7561 ccaactttct cgagtggtcc aatcgatcgc tttaagcgat ttaatgaaaa ttatcaggct
     7621 attcctgagc gagatgagtt gatggatatg ctggatgaat ctgtccgcta tatcatgtgg
     7681 ggctttttgt ataagtttat cctagctcat gttttaggag agaccttact acctcctctg
     7741 aagaatttag ccttgcagtc aggtggcttc tttaatctct atgccttggc agttatgtat
     7801 acttttggtc tggagctctt ctttgacttt gcaggttatt ctatgtttgc tttggccatc
     7861 tcaaacttga tgggaatccg tagccctatc aactttaaca agcccttttt atcaagggat
     7921 ttaaaggagt tttggaatcg ctggcatatg agtctgtcct tctggttccg tgactttgtc
     7981 tttatgcgaa tggtgatggt gttaaccaga aagaaagtct ttaaaaatcg taatgtaacc
     8041 tcaagcatgg cctacattgt aaatatgctg attatgggat tttggcatgg tgtgacctgg
     8101 tactatatcg cctatggact ctttcatgga ctaggcttgg tcatcaatga tgcctgggtt
     8161 cgcaagaaaa aaacgctcaa taaggaacgg aaaaaagcag ggaaggctgc cctacctgag
     8221 aatcgctgga ttcagttgct tggcatggtt gtcactttcc atgttgtcat gttgtcattc
     8281 ttaatctttt ctggattctt gaataatcta tggtttaaaa aataaaagga aataaaatat
     8341 ggatatcaaa tcagaagtta ttgaaattat tgatgagttg tttatggaag atgtttctga
     8401 catgatggat gaagatcttt ttgatgcagg tgtcttggat agtatgggaa cggttgagtt
     8461 gattgtggag attgagaacc gttttgacat tcgtgtccct gtaacagagt ttggtcgtga
     8521 cgactggaat acagctaata aaatcatagc tggtattgtg gagctacaaa atgcttaaac
     8581 gcttatggat gatcttcgga ccggtcttga tcgctggttt gttggttttt ctgctcattt
     8641 tcttttatcc tactgagatg catcataatc taggagctga aaagcgttca gcagtggcta
     8701 ctactatcga tagttttaag gagcgaagtc aaaaagtcag agcactatct gatccaaatg
     8761 tgcgttttgt tcccttcttt ggctctagtg aatggcttcg ttttgacggt gctcatcctg
     8821 cggtattagc tgagaaatac aatcgttcct accgtcctta tcttttagga caggggggag
     8881 ctgcatcgct taaccaatat tttggaatgc aacagatgtt accacagctg gagaataaac
     8941 aagttgtgta tgttatctca cctcagtggt tcagtaaaaa tggctatgat ccagcagcct
     9001 tccagcagta ttttaatgga gaccagttga ctagttttct gaaacatcaa tctggggatc
     9061 aggctagtca atatgcagcg actcgcttac tgcaacagtt cccaaacgta gctatgaagg
     9121 acctggttca gaagttggca agtaaaggag aattgtcgac agcagacaat gaaatgattg
     9181 aattattggc tcgttttaat gaacgccaag cctccttttt tggtcagttt tcggttagag
     9241 gctatgttaa ctacgataag catgtagcta agtatttaaa aatcttgcca gaccagtttt
     9301 cttatcaagc aatagaagat gttgtcaaag cagatgctga aaaaaatact tccaataatg
     9361 agatgggaat ggaaaattat ttctataatg agcagatcaa gaaggatttg aagaaattaa
     9421 aggattctca gaaaagcttt acctatctca agtcgccaga gtataatgac ttgcagttgg
     9481 ttttaacaca gttttctaaa tctaaggtaa acccgatttt tatcattcca cctgttaata
     9541 aaaaatggat ggactatgct ggtctacgag aggatatgta ccaacaaacg gtgcagaaga
     9601 ttcgctacca gttagaaagt caaggtttta ccaatatagc agatttttct aaggacggtg
     9661 gggagccttt ctttatgaag gacaccattc accttggttg gttgggttgg ttggcttttg
     9721 acaaggcagt tgatcctttc ctatccaatc ccacaccagc tccgacttac catctgaatg
     9781 agcgcttttt cagcaaagat tgggcgactt atgatggaga tgtcaaagaa tttcaataga
     9841 taatataata tagaagagtt caagaatgaa actagttttc acgttttttc ttgactcttt
     9901 ttttgcttgt gatataatta actggtaaac aaaatgtcaa agaatagtat ttttctctta
     9961 aaaaagagaa gtctaaaagg aaaggagtca gatatgagac agctagcaaa ggatatcaat
    10021 gcttttttga atgaggtgat tttgcaggcg gaaaatcagc atgaaatcct aataggtcat
    10081 tgcactagcg aggtggccct gaccaatact caggagcata tccttatgct cttgtcagag
    10141 gaatctttaa caaattcaga attggcccgt cgtctcaatg tcagtcaggc ggcagttacc
    10201 aaggccatta agtctttggt caaggaaggg atgttggaaa catctaaaga ttctaaagat
    10261 gcgcgtgtga ttttttatca gttgactgac ttggctcgtc caatcgctga ggagcaccac
    10321 catcaccatg agcatacact tttaacctat gaacaagtgg cgactcagtt tactccaaat
    10381 gaacaaaaag tgattcagcg gtttttgact gctttagtag gagaaatcaa ataatgagat
    10441 atattacggt agaggatttg tccttctatt atgataagga gcctgttctt gaacatatca
    10501 attatagtgt tgatagtggg gaatttgtta ccttgactgg ggaaaatgga gcggctaaga
    10561 cgacgctcat caaggccagt cttggaattc tgcaaccacg cattggaaag gtggctattt
    10621 caaagacaaa tacgcaaggt aagaaattga gaatagccta tcttcctcaa caaattgcca
    10681 gttttaatgc tggttttcca agtacggtct atgaatttgt caagtcgggt cgctatccga
    10741 gaaaaggctg gttccgtcgt ttgaatgctc atgatgagga gcatatcaag gccagtctgg
    10801 actcagttgg catgtgggaa catcgagaca aacgcttggg gtctctatct gggggacaaa
    10861 agcagcgagc ggtaattgcg cgtatgtttg cttctgaccc tgatgtgttt atcctagacg
    10921 agccgacaac ggggatggat gcaggaagta aaaatgaatt ttacgaactc atgcaccaca
    10981 gcgcccatca tcatggcaag gctgttttga tgattaccca tgaccctgaa gaagttaagg
    11041 attatgcgga tcgcaatatt catctagtcc gtaaccaaga ctcgccatgg cgttgtttca
    11101 acgttcatga gaatggccag gaggtgagcc atgcttagtt tattatctta cgactttata
    11161 caacgcgcct ttttggcggt tattgctatg agtcttttct caccggtatt gggaaccttc
    11221 ctcatcttgc gtcgtcagag tttgatgagt gataccctta gccacgtctc actttcaggt
    11281 gtagcctttg gtctggtttt ggggatttct ccaactgttt ctactattgc cattgtcttg
    11341 attgcggcgg tctttctgga gtatctccgt acggtttaca agagctttat ggaaatcggg
    11401 acagctatcc tcatgtcaac aggtctggct gtttctctga ttgtcatgag caagggtaaa
    11461 agctcgagtt caatgagttt ggaccaatat ctctttggtt cgatcgtgac tatcagtgaa
    11521 gaacaggtca tttccctctt tgtcattgcg gcggttgttt tgattttgac ctttctcttt
    11581 cttcgtccta tgtatatctt aacttttgat gaagatacgg cctttgtgga tggcttgcca
    11641 gttcgtacca tgtccattct ttttaacatg gtgacagggg tggctattgc ccttatgatt
    11701 cctgcagcag gagctcttct ggtatcgacc attatggtct tgccagctag tattgccctg
    11761 cgtctgggga aaaactttaa atcggttatg ctgcttgcca gtgcgattgg ctttttggga
    11821 atggtagcag gactttacat ttcctactat gcagaaacac ctgcaagtgc aagtattacc
    11881 attatttttg taactgtctt tatactaatc agtttagtaa gacgttttat caaataggag
    11941 acgaacgtga aaaaaattag cttattacta gccagtctat gtgccttgtt tttagtggct
    12001 tgttccaatc aaaaacaggc agatggtaaa ctcaatatcg tgacaacctt ttaccctgtc
    12061 tatgaattta ccaagcaagt cgcaggagat acggctaatg tagaactcct aatcggtgct
    12121 gggacagaac ctcatgaata cgaaccatct gccaaggcag ttaccaaaat ccaagatgca
    12181 gataccttcg tttatgaaaa tgaaaacatg gaaacatggg tacctaaatt gctagatacc
    12241 ttggataaga aaaaagtgaa aaccatcaag gcgacaggcg atatgttgct cttgccaggt
    12301 ggcgaggaag aagagggaga ccatgaccat ggagaagaag gtcatcacca tgagtttgac
    12361 ccccatgttt ggttatcacc agttcgtgcc attaaactag tagagcacat ccgcgacagc
    12421 ttgtcagcag attatcctga taaaaaagag acctttgaga agaatgcagc tgcctatatc
    12481 gaaaaattgc aagccttgga taaggcttac gtagaaggct tgtctcaagc aaaacaaaag
    12541 agctttgtga ctcaacacgc agcctttaac tatcttgcct tggactatgg actcaaacaa
    12601 gtcgcaatct caggactttc tccagatgca gagccatcag ctgctcgctt ggcagaattg
    12661 acagagtatg tcaagaaaaa taaaatcgcc tatatctatt ttgaagaaaa tgcctcacaa
    12721 gcccttgcta acacactttc aaaagaagca ggtgtcaaaa ctgatgtcct caatccttta
    12781 gaaagtctga cagaagagga caccaaggct ggagaaaatt acatctctat catggagaaa
    12841 aacctcaagg ctttgaaaca aacaacagac caagaaggcc cagcaatcga gcctgaaaag
    12901 gcagaggata ccaagacagt ccaaaatggt tacttcgagg atgcagctgt caaggaccgc
    12961 accttgagtg actatgcagg taactggcaa tcagtttatc ctttccttga agacggcacg
    13021 tttgaccaag tctttgacta caaggctaag ttgactggta agatgaccca ggctgagtac
    13081 aaggcttact atacaaaagg ctatcagaca gatgtgacta agattaacat tactgataat
    13141 actatggaat ttgttcaagg tggacaaagc aagaaataca cttacaagta tgtcggtaag
    13201 aaaattttga cttacaagaa aggcaatcgt ggcgtgcgtt tcctctttga agccacagat
    13261 gctgacgctg gacaattcaa gtatgttcag tttagtgacc acaatatcgc cccagttaag
    13321 gcagaacatt tccatatctt ctttggaggc acaagccaag aagccctctt tgaagaaatg
    13381 gacaactggc caacctacta cccagataac ctatctggcc aagaaatcgc ccaagaaatg
    13441 ttggcgcatt gatgagaaat cgactagttc ataagagcta gtcggttttt tgatactaga
    13501 tggctaactt cattatagac ctttcagaac taagggaacc tgaaaaaata aataaaactc
    13561 ttgaaatatt aggacttata tgctagaatg tagttagtgt ataaggttca ttagaacacc
    13621 aaagccccta actagtgcca tagttaaggg cttttttgac gtatcttaga gatttaacgg
    13681 gtgtttatag gctagtcagt cggtctactt cttaccatct agccatttgc agacgaaata
    13741 caagataatt ccagctataa catctgctat aatagtaaga gcaagctctg gtataaggct
    13801 cattagtttc acctcctctc acgaacccat aggaacgtaa tcggtaaccg atgacaaaaa
    13861 tagtatacca cactaaattt agatcatcaa cctcacttaa tgcttgaact attgtagatt
    13921 atatgctaaa atgtagttaa ttgataaggt tcattagaac accaaagccc ctaactatgg
    13981 ccgtagttaa gggctttttt gacgtatctt agagatttaa cgggtgttta taggctagtc
    14041 attcggtcta ctccttacta tctagccatc tgcagatgaa atacaagata attccagcta
    14101 taacatccgc tataatagta agagcgagct ctatgataag gctcattagt ttcacctcct
    14161 ctcacgaacc cataggaacg taatcggtaa ccgatgacaa aaatagtata ccacaataca
    14221 tttagatcat caaggtcact taattcttga aatatagggt ctaggcgaca aagtctttaa
    14281 aatcagaaaa acgcataata tcaggtgtgc aaaaacttga tactatgcgt tttattgtgg
    14341 gaatatttgc cccatttctc ttgaaattga gtttttgtcc agcctctgtt tttagggttg
    14401 ctaagaaaat aatgtcatgt ggtgaatatt tgtaaatcag tcagcagaca gaacgagtat
    14461 tcttcgaaaa tctcttcaca tcatgtcagc ttcgtcttgc cgtgtccatg ggggacttga
    14521 cttcatcagt tttcaaatct gtactttgag caagctgaga ctagcttcct atttgatttt
    14581 cattgaatat cagaaaccca ttctccatca aataattcga ctgcgtctaa taatttttga
    14641 tctggcacgg tgtcagaaat aaaggttgtg tatttggata ggggattaat tttaaaaaat
    14701 ccagtcttgt aaaatttaga gctatcaatc agtaagatgg tttcatgggc tttgtcaata
    14761 atattctttt ttgaaatagc ttggctgaga gaagcttcat aaacatattg gtcatcaata
    14821 cctcttgctg aacaaaatgc taaatcgata ttaaaatgat ctaataaaga attttcctta
    14881 tcatagttga ccacggaaca ggattgatgt ttgacctcgc cagatgtgat aaagattttg
    14941 gagctatctt taacagtttc agatagggtt tgtgcagtat gtaaaccatt tgtaaaaata
    15001 atcaaattat caagttcaga aagataggga cagagttcgt agacagtcgt actggaatcc
    15061 agatagatac acataccaga ccgaataaag tctttagcga gactagcgat tagtcttttt
    15121 tgcctagtac tttctccttc ccgtatttga tgagaaagtt caattgtgtt catagaggac
    15181 agggtcacgt atccgtgctt tcttttgata agaccttgat tttctaagaa aattaaatca
    15241 cgacgtaagg tacttgtgct ggagaaagtg atttctgcca gctcttttac ggcaattctt
    15301 tttttctttt tgataatttc aatcaattca agtacacgtt catcttttat cataagctcc
    15361 tcctaattta tcatttcaac tatattatag cacaaattgg aggaatttga attattttta
    15421 tgaatattgg gttaacattt gaacattatt caagtaagcg ttcacatatt gaaaaaataa
    15481 aacgtgggga ttataataaa gttaatcaag gacgaagaga gaagaaaaat ggaagcggtt
    15541 ttagcaatag atttaggtgc gacttctgga agagcaatcg ttggttacct ttctgaaaat
    15601 aaactagtaa tggaagaaat aaatcgcttt tctaatctac ctattagagt aaaagggcat
    15661 ttatcttggg atattgactt tctactagct aaaattcttg aaagtatccg cttggctaat
    15721 actagttaca agattttatc tatcggtatt gacacatggg gagttgattt tggactgatt
    15781 gataatgaag gtaagctgtt atcacaacct gttcattatc gtgatgaaag aacaaaggga
    15841 gtgttaaagg aaatatctga aatgactgaa ttagaaaaac tgtattcaga gacaggaaat
    15901 cagattatgg agataaatac cttgtttcaa ctctttaagg cacgtcaaga atctcctgac
    15961 tctttctata agaccaataa gattctttta atgccagatt tgtttaatta tctcttgaca
    16021 ggtaagtttg ctacagaaaa aagcattgct tcaacaactc aattatttga tcctaggagt
    16081 caaaattgga atcaaaatat cttaaaacta tttgaattgg attcatcttt acttcctgaa
    16141 attgtttcag agggaaatgt tcttggaagg ataaaaaagg agtatggttt aggcgatatt
    16201 cctgttgtga atgtttgtag tcatgataca gcaagtgcga ttgtctcagt acctaagaca
    16261 gaaggtagtt tatttatttc atcaggtact tggtctttgg ttggagtgga acttacttca
    16321 ccgattctta ctaccgaatc cttcagttat ggatttacaa atgaagtcgg taaagatgga
    16381 gtgattacat ttctgaagaa ttgtacaggg ttgtggatca tagaggaact aagacgttcg
    16441 tttgaacgaa gagggaaagc ctattctttt gatgatatta ggacaatggt ggagaaagaa
    16501 aaagaaaatc ttcctctgat tgatactgaa tcaactgaat ttgcaacaga atctgatatg
    16561 cacaagactt tgacagaata tctagcttat catcatgaaa ctagagagtg gacagatgga
    16621 caactattta agattgttta tgaaagccta gctgaaacgt ataggaaagc gatagagtta
    16681 ctagaagaac taactcataa ggtttataag aggatatatg tgattggagg aggtgctaga
    16741 gccagttatt ttaaccaaat gattgctgat agaactggta aagaggttct tacaggtttg
    16801 actgagggta cagctgtggg gaatattgtt gtgcagctca tagctatggg acaattaaaa
    16861 gggatggaag aagctcacca tgttattgag gagttcctac aattagagag ttattactcc
    16921 caaaagaatt aaaaagattg agagtttgta aatttgcctc cctccccctt cttaagtttt
    16981 gtacaagaag gggggataat tggtgaattg aaaaatattt agtgttttga tatgaggagg
    17041 ataagaatgt cagatgtaaa acaagaatta attaagtatg gcaagaagct ggtagaaaca
    17101 gatttgacga aaggaacagg tgggaatctc agtgttttcg atcgtgaaaa acaattgatg
    17161 gcaattaccc cgtcgggtat tgatttcttt gaaatcaaag aatccgatat tgtagtgatg
    17221 gatattaatg gaaatgttgt agagggagaa cgcttgccat ctagcgaatg gtatatgcat
    17281 ttgattcaat atcaaactcg tgatgatatc gatgcaatta tccatgctca tacaacttat
    17341 gcaacagtat tagcttgtct cagagaacca cttccggcga gtcattatat gattgcagtg
    17401 gcagggaaag atgttcgggt agctgagtat gcaacatatg gtacgaaaga attggctgtg
    17461 aatgcagcta aagcaatgga aggtcgtaga gcagttttac tagcgaatca tggaatttta
    17521 gcaggtgcac aaaatttatt gaatgcattt aatattgttg aagaagttga atattgtgca
    17581 aaaatttatt gtttagctaa gaattttgga gagccagtag ttcttcctga tgaggagatg
    17641 gatttaatgg cagaaaaatt taaaacatac ggtcagagaa aatagggagg atattaatgt
    17701 taaaacatat accgaaaaat atttctccag atttattgaa gactttaatg gaaatgggac
    17761 atggagatga aatagtatta gctgacgcga attatccttc tgcctcatgt gcaaataagc
    17821 taattcgttg tgatggtgta aatattccag aattattaga ttccattctg tatttaatgc
    17881 cattagatag ttacgtcgat agttcaattc agtttatgaa cgttgtttcg ggtgatgata
    17941 ttcctaagat atggggtacc tatagacaga tgattgaagg tcatggtaca gatcttaaaa
    18001 cgattactta tcttagaaga gaagactttt atgaacgtag taagaaagct tatgctattg
    18061 ttgctacagg agaaacttca ctttatgcta atattatcct taagaaagga gtagttgttg
    18121 aaagagaaaa tgtttaatag aggaatttta gttgccagtc atggtaattt tgctagcgga
    18181 gctctcatga ccgcagaaat gtttgttggt gagacaacaa atgatagagt taggacatta
    18241 ggtttgatgc ctggagagaa tattgtagag tttgagcatt attttaaaaa tcaagtggat
    18301 gaactgttag actcaaatca agaggttatc gttttgactg acttgattgg aggaagtcct
    18361 aataatgtgg ctttgtcacg gtttttaaat tttgattcag ttgatattgt aacagggttt
    18421 aatatccctc tcctagtgga attaatatca agttatgatt caaaaatcaa tttagaagaa
    18481 attgttcaca atgctcaaaa tagtttgttt aatgttaaac aacaacttaa cgtagaggag
    18541 gaagaagatt tatgtctata gagtttgttc gtattgatga ccgtctggta catggtcaag
    18601 ttgtcactac gtggctaaaa aagtatgata ttgagcaagt tatcattgtt aatgatcgca
    18661 tctcagaaga taaaacacga caatctattt taaagatttc tgcaccggta ggtttaaaaa
    18721 ttgttttctt tagtgtaaaa cggtttgtgg aagttttaaa ctctgtgcca ataaaaaaga
    18781 gaacaatgct gatatataca aatccaaaag atgtgtatga ttctattgaa ggaaatttaa
    18841 aattggagta cctcaatgta ggacagatga gtaaaacgga ggaaaatgaa aaggtaacgg
    18901 gaggtgtagc tctaggtgaa gaagacaaat attattttaa gaaaatagtt gataagggaa
    18961 cgagagttga aattcaaatg gttcctaatg ataaagttac aatgttggaa aaatttttat
    19021 aaaaataatt taaggaggta cagtatatgc tattcacaca agcattactg gtgacattag
    19081 ttgggattat tgccactatt gactataatg gaccgttatt tatgattcac cgtccgttag
    19141 ttacaagtgc aatggttggc ttagtattag gagatttcac ccaaggtgtt cttattggtt
    19201 cagctcttga attaacttgg ctcggtgtaa caggtattgg aggttatact ccaccagata
    19261 ctatttcagg tgcgattatt ggtactgcat ttggtatttt atctggtcaa ggagaaactg
    19321 ctggtatcgc tatagcagtt ccaattgcag ttgctaccca acagttggat gttcttgcaa
    19381 aaactttaga tgtttatttt gtgaaaaaag ctgataatga tgctaaaaac ggagattatt
    19441 caaagatcgg tttttatcat tattcaagtt tggttttaat cacgttattt aaaattgtac
    19501 caattttcct agctattatg cttggagggg aatatgtggc agacttgttt gctaaggttc
    19561 caccaatcgt tatgcaggga cttaactctg caggtgcttt actaccttca attggttttg
    19621 gtatgctttt aaatatgatg ctcaagaaaa atatgtgggt attcttgttg attggattca
    19681 tttgttctgt gtatggagga atgtcaacca ttgggatctc actagttggt attgcggtag
    19741 catacttcta cgatatgatt ggaagcaaac cacaagaaac aacttcaagt agtgatgttg
    19801 aggaggatct tgatctatga tgaataataa agtaactaaa gttgaactta aaaaagtttt
    19861 caaacgaagt tttatgtatg gttcttcatg gaactatgag agaatgcaga acctaggttt
    19921 tctatataca attcttccag tattgaaaaa actataccca gacaaagatt cagcttctcc
    19981 tgcaatgaaa cgtcaccttg agtttttcaa tactcatcaa acagcggcac catttattct
    20041 tggagttact tccgctatgg aagaacaaga aggaaatgaa ggtgcagctt caattactgg
    20101 tattaaagtt ggcttgatgg ggccactggc tggtctagga gatagtttgt tctggctgac
    20161 actagttcct atctgtttta gtattggtgc gtcttattct aaagacggcg gtgctttagg
    20221 tatctttatc gccttaatat tgtttaatat tattaatatt cctgttaaat atttcggttt
    20281 gaaatatggg tatactaagg gttctagtct tatccaagaa aataatacaa aaggaacatt
    20341 gaatcgcgtt acgagtatgg cgacagcatt agggctagta ctagtgggtg gtttgattcc
    20401 atcaatggtt ggtattaatt ttggattaga atttaagcag ggggaacttg ttatttctgt
    20461 tcaagaaatg attacaaaat taattccagg atttatccct atggctttga ctttattaat
    20521 gtgtaaatta attagaaaag gaaagaatcc ggttgtacta atctttagtg ttatggctat
    20581 tggagttatt ctagttgttt taggaatttt gaagtagtag aaagtgtgga ggtggtattt
    20641 gggatatcac ctccattttg gaagagaggt aaagagtgaa attatggtat aagaaagctg
    20701 ccgcaaattg gaatgaagcc ttgccgattg ggaacggtca tttaggtggt atgatttatg
    20761 gttcagctac aaaagaatgt attcaactaa acgatgagac tatttggtat agaggaaagt
    20821 cagatagaaa taatccagac tcactattgc atcttaaaaa aattcgggaa tatcttttag
    20881 atggagaaat tcagaaagcc gaagaattga taaagttaac agtgtttgct accccaagag
    20941 atcaaagcca ctatgaatta cttggggaac tttacattga gcatatagat attcagtctt
    21001 gtgctctttc attgtatgaa agagagctag atttagatac agctatttct aatgttgtgt
    21061 ttgagcctaa tagttgtaat ttacaaataa aaagagaata ttttacgagt tttaataaga
    21121 atattttatg ttgccgtata gtgtcatcag ttcaaaacac attaaattta aacattaatt
    21181 tgggtagaaa taaacggttt aatgacgaag tatctaaact ggattcaagt acaattttaa
    21241 tgtcggcctc tgctggaggt agaaaaggtg ttcagtttaa agtagtatgt cattctaagg
    21301 ttacggatgg tgaagtaagt gtattgggag agacaatagt tattcggaat gctacagagg
    21361 tatttcttta tctcaaatca atgacggatt attggggaaa tatagatatt tcttctcttc
    21421 agggagaatt tagtagtatt gattacttta cagaaaaaga tgaacatgta aaaaaatatc
    21481 aggagcaatt taatagagtt gattttaaac tagactatag taaaggttgt cttagcattc
    21541 caacgaatct acttcttgaa aacactaaaa agtatagtaa ctacttgact aacttgttat
    21601 ttcattatgg aagatatctg ttaatatcgt ctagtcaacc gaatggttta cctgccaatc
    21661 ttcaaggaat atggtgtgat gaattaaatc caatttgggg ttctaaatat acgattaata
    21721 ttaatactca aatgaattat tggatggtag gtccatgtga tttaccagaa gtagaatatc
    21781 cattatttga tatgctcgaa agaatgagag aaccgggaag actaaccgct aagaaaatgt
    21841 atggagctag aggttttaca gcacatcata atacggatgg ttttggcgat acggctcccc
    21901 aatctcatgc catgggggct gcaatttggg tattaactat tccatggtta tgtactcata
    21961 tttgggaaca ctatttatat ttccaagatg agcgtattct tacggaacat tttgaaatga
    22021 taaaagaagc atttcttttc tttgaagatt atttatttga ggtggatggc tacttgatga
    22081 caggtccaag tgtctcaccg gaaaataaat atcgcttaaa aaatggtatt gaaggaaatg
    22141 cttgtctatc atctacaatt gataatcaaa ttttaagata tttttgtgat tcatgcattg
    22201 gaattgcaaa acaattagga gacaattcgg attttattag tcgtgtgaag gagttaaaaa
    22261 agaaattacc tagaacaaaa ataggtagta atgggcaaat acaagaatgg ctagaggatt
    22321 atgaagaagt agagcctggt catagacaca tttcacctct atttgggctt tatccttata
    22381 atgagattga tattcataaa actccggaat tagcagaagc agctaaaatc actatcaata
    22441 ggagattatc aaacgctaac tttttatctt cacaggatag ggagcaagcg attaataatt
    22501 ggttagtaag tggtttgcat gctagtacac aaacaggttg gagtgctgca tggctgattc
    22561 atttttttgc gagactatat caaggtgaac ctgcttataa ccagattaat ggtttgttaa
    22621 ataatgcgac tcttggcaat ttatttcttg accatccacc atttcaaatt gatggtaatt
    22681 taggtttggt gagtggaatt tgtgaattat tagtacagag ccatcataat tggttatcac
    22741 taattccagc tttaccttct gcttggtcag aaggagaagt gaaaggtttc agagtaagag
    22801 gaggatataa ggtatcgttt gcttggaaaa atggggatat aacattccta aaattggaag
    22861 gaggaaacaa agatcaaaaa gtaagagtaa gaatatatgg caaaaatact gatgtacaaa
    22921 atattgaatt ggtatttaat tcagaaaaaa ttattgagtt aaatttttag gtataagtca
    22981 tgaataaaga aaaaataaaa agaaaattaa tcacaatact gtttgtatgt attgggatgt
    23041 tatgttttgg attgttagca ggagttaagg ctgataatcg tgttcaaatg agaacgacga
    23101 ttaataatga atcgccattg ttgctttctc cgttgtatgg caatgataat ggtaacggat
    23161 tatggtgggg gaacacattg aagggagcat gggaagctat tcctgaagat gtaaagccat
    23221 atgcagcgat tgaacttcat cctgcaaaag tctgtaaacc aacaagttgt attccacgag
    23281 atacgaaaga attgagagaa tggtatgtca agatgttgga ggaagctcaa agtctaaaca
    23341 ttccagtttt cttggttatt atgtcggctg gagagcgtaa tacagttcct ccagagtggt
    23401 tagatgaaca attccaaaag tatagtgtgt taaaaggtgt tttaaatatt gagaattatt
    23461 ggatttacaa taaccagtta gctccgcata gtgctaaata tttggaagtt tgtgccaaat
    23521 atggagcgca ttttatctgg catgatcatg aaaaatggtt ctgggaaact attatgaatg
    23581 atccgacatt ctttgaagcg agtcaaaaat atcataaaaa tttggtgttg gcaactaaaa
    23641 atacgccaat aagagatgat gcgggtacag attctatcgt tagtggattt tggttgagtg
    23701 gcttatgtga taactggggc tcatcaacag atacatggaa atggtgggaa aaacattata
    23761 caaacacatt tgaaactgga agagctaggg atatgagatc ctatgcatcg gaaccagaat
    23821 caatgattgc tatggaaatg atgaatgtat atactggggg aggcacagtt tataattttg
    23881 aatgtgccgc gtatacattt atgacaaatg atgtaccaac tccagcattt actaaaggta
    23941 ttattccttt ctttagacat gctatacaaa atccagctcc aagtaaggaa gaagttataa
    24001 atagaacaaa agctgtattt tggaatggag aaggtaggat tagttcatta aacggatttt
    24061 atcaaggact ttattcgaat gatgaaacaa tgcctttata taataatggg agatatcata
    24121 ttcttcctgt aatacatgag aaaattgata aggaaaagat ttcatctata ttccctaatg
    24181 caaaaatttt gactaaaaat agtgaggaat tgtctagtaa agtcaactat ttaaactcgc
    24241 tttatccaaa actttatgaa ggagatgggt atgctcagcg tgtaggtaat tcctggtata
    24301 tttataatag taatgctaat atcaataaaa atcagcaagt aatgttgcct atgtatacta
    24361 ataatacaaa gtcgttatcg ttagatttga cgccacatac ttacgctgtt gttaaagaaa
    24421 atccaaataa tttacatatt ttattgaaca attacaggac agataagaca gctatgtggg
    24481 cattatcagg aaattttgat gcatcaaaaa gttggaagaa agaagaatta gagttagcga
    24541 actggataag caaaaattat tccatcaatc ctgtagataa tgactttagg acaacaacac
    24601 ttacattaaa agggcatact ggtcataaac ctcagataaa tataagtggc gataaaaatc
    24661 attatactta tacagaaaat tgggatgaga atacccatgt ttataccatt acggttaatc
    24721 ataatggaat ggtagagatg tctataaata ctgaagggac aggcccagtc cctttcccaa
    24781 caccagataa atttaatgat ggtaatttga atatagcata tgcaaaacca acaacacaaa
    24841 gttctgtaga ttacaatgga gaccctaata gagctgtgga tggtaacaga aatggtaatt
    24901 ttaactctgg ttcggtaaca cacactaggg cagataatcc ctcttggtgg gaagtcgatt
    24961 tgaaaaaaat ggataaagtt gggcttgtta aaatttataa tcgcacagat gctgagactc
    25021 aacgtctatc taattttgat gtgattctat atgacaataa tagaaacgaa gttgctaaga
    25081 aacatgttaa taatttgtcg ggtgaatctg ttagtctaga tttcaaagaa aaaggagcaa
    25141 ggtatattaa agttaaatta ctaacgagtg gagtgccttt gagtttagca gaagtagagg
    25201 tttttagaga atcagatggt aagcaatctg aagaggatat agataaaata acagaagata
    25261 aagtagtctc tacaaataag gtagctactc aaagttcaac caattatgag ggtgtagctg
    25321 ctttagcagt tgatggtaat aaagatggag attacggaca tcattcggtg actcatacta
    25381 aggcagattc taacgcttgg tggcaggttg atctgggaga agagtttacg gtttctaaag
    25441 ttgatattta taatagaaca gatgccgaac ctcagcgttt atctaatttt gatgttattt
    25501 ttctatcttc atcaggagaa gaagttttta gaagacattt tgataaagta gttgatggtt
    25561 tgttatcttt aaaagtacct tctgtagggg ctaagctagt caaaatagaa ttaaaatcag
    25621 cagctattcc gttaagttta gcggaagttg aagtctatgg ttcaaagaga actccgaaga
    25681 aactttctaa tattgcatta accaaagaaa ctcgacagag ttcaacggat tacaatggtt
    25741 tttctcgtct agcagttgat ggaaataaaa acggagatta tggtcatcat tcagtgactc
    25801 ataccaaagg agattctcct tcatggtggg agatagattt agcacaaacc gaagaattag
    25861 aaaagttaat tatttataat agaacagatg ctgaaattca gagattatca aattttgata
    25921 ttattatata tgattcaaat aatcatgaag tttttaaaca acatattgac agtttagaaa
    25981 gcaataatct atccatagac ttaaaagggc tgaagggaaa aaaggttaga atttctttga
    26041 gaaacgcagg aattccttta agtttagcag aggtagaggt ttatacttat aagtaatttt
    26101 aaaaattatc acccaggcta ccgtaaatat aatggcgatg gtagtatgaa agaaacagaa
    26161 aaataagagg aaaatagtat gattcaacat ccacgtattg gtattcgtcc gactattgat
    26221 ggtcgtcgtc aaggtgtacg cgaatcactt gaagtgcaaa caatgaacat ggctaaaagt
    26281 gtggcagatt tgatttcaag cacattgaaa tatccagatg gggaacctgt ggaatgcgtg
    26341 atttctccat ctactattgg ccgtgtacca gaggctgcag cttcccatga gttgtttaaa
    26401 aaatcaaatg tttgcgcaac aattacagtt acaccatgct ggtgttatgg tagtgaaact
    26461 atggatatgt ctccagatat tcctcatgct atttggggat ttaatgggac agaacgccca
    26521 ggagctgtct atcttgcagc tgtactagct tcacatgctc aaaaagggat tccagccttt
    26581 gggatctatg gtagagatgt tcaggaagct aatgatacag ctattccaga agatgtcaaa
    26641 gaaaaacttt tacgttatgc gcgggcagct cttgcaactg gcttgatgag agacactgct
    26701 tacctatcaa tgggtagtgt ttcgatgggg attggtggtt ctattgtaaa tccggatttc
    26761 ttccaagaat acttaggaat gcgaaatgaa tcggtagata tgacggagtt cacacgccgt
    26821 atggaccgtg gtatttacga ccctgaagag tttgaacgtg ctatggtttg ggtaaaagaa
    26881 catatcaaag aaggagttga ccgaaatcgt gaggatttga ttctttctaa agaagagaaa
    26941 gaaaaacaat gggaatttgt tattaagatg ttcatgattg gacgtgactt aatggttggt
    27001 aacccaagac ttgctgaact tggttttgag gaagaagcag ttggtcacca tgctttagta
    27061 gctggtttcc aaggtcaacg tcagtggaca gaccattttc caaatggaga ttttatggaa
    27121 actttcctca atactcagtt tgactggaat ggtattcgaa aaccatttgt atttgcgaca
    27181 gagaatgatt cactaaatgg tgtgtctatg ctctttaatt atctattaac aaatactcca
    27241 caaatctttg ctgatgtgcg tacttattgg agtccagagg ctgttgaacg tgtaacagga
    27301 catactttag agggtcgtgc tgcagctggc ttcttacatc taatcaactc tggatcttgt
    27361 acattggatg gtacaggtca agctactcga gatggcaaac ctgttatgaa accattctgg
    27421 gagttggaag aaagtgaagt gcaggctatg cttgaaaata cagacttccc accagcaaac
    27481 cgcgaatact tccgtggagg aggattctca actcgtttct tgacgaaggg ggatatgcca
    27541 gtaacaatgg tacgtctcaa tcttctaaaa ggggttggtc cagtgctaca aattgcagaa
    27601 ggttacacac ttgaacttcc tgaagatgtt caccatactt tagataatcg tacagatcca
    27661 ggatggccaa ctacttggtt tgctccacgt ttgacaggaa aaggtgcttt caagtctgtc
    27721 tatgacgtca tgaataattg gggagctaat cacggagcca taacatatgg ccacattgga
    27781 gcagacttga ttaccttggc ttctatgttg agaattcctg tcaatatgca taatgtacct
    27841 gaggaagata tctttagacc taaaaattgg tccttatttg gaacagaaga tctagaatca
    27901 gcagactatc gtgcatgtca gttgttggga ccactacata aataaaactt gtttatatag
    27961 gaggtgaact tacgtccctc ctatcctttt aaaaagattt gttaaacaat tcacaaataa
    28021 ttgaaaacga atacaaaaag taatataatg atgttaaata gatagcgcgg aggcgcagga
    28081 ggaaaattat atggctatat tttatgttcc ggcagtcaac cttattggaa aaggtgttgt
    28141 aaatgaagtg ggtccttata tcaaggaact tggctataaa aaggcacttt tggttacaga
    28201 taagtacatc gaaggcagtg atattttacc taaggtttta aaaccactgg atacagaagg
    28261 aatcgaatat gtcatcttta gcgatgtaga gccaaaccct acttgtaaga atgtcacaga
    28321 tggggtagct gctttgcaag aacatggctg tgattttatc atcagtcttg gcgggggttc
    28381 tccacaggat gcagctagtt gtatttctat catggctaca aatggtggaa aaccacagga
    28441 ttatgaaggg cttcataagt ctgctaaaaa aggccttcct gttgtagcta tcaatactac
    28501 ggcaggtaca tcagcagaaa ttaccattaa ctatgtgatt actgatgaag aacgcaaggt
    28561 taagatggta atggttgaca agaatagcct tgccttgatt tctgtcaatg accctgaact
    28621 catgctttcc aaacctcaag ccttgactgc tgctactggt atggatgctc tgactcacgc
    28681 tgttgaagct ttggtaacac ctggtgctta tgatgtaacc aagaaactgt ctattggtgc
    28741 tattgagctt atcaaggaat atcttcctcg tgctgtagca aacggacatg atattgaagc
    28801 gcgtgaaggt atggtcaatg ccatcttcct tggtggtatg agctttaata atgctggtct
    28861 tggctatgtt cactcaatgg ctcaccaact cggtgcagta tataatttgc cacatggtgt
    28921 ttgctgtgcc atgttgctac cagttataga acgtgaaaat gctaaacgtg taccagaagc
    28981 tttccgcaat gttgccaaag ccttgggact tcatgtagaa ggtaaatcag atcaagaatg
    29041 tgccgattat gcgattgctg agattgagaa gctttctgag acagtaggta ttcctaagaa
    29101 actgactgaa cttggtattg aagaaaaaga tttcgacttt gaataccttt ctaagaatgc
    29161 cttgattgat gcctgcgcac caggaaatcc atttatgcca accttagaag aaacgattgc
    29221 cttttataaa gagttatttt agcaaggatt agacgacaat aggacaattc acctctaatt
    29281 attgacattt caggaaaaat cgcagtaaaa acggcacagc cttctttaaa tgtgctataa
    29341 tactagaaaa atacttgtgg aggttccatt atggcaatat ttttcatgat ttttctgatt
    29401 gtttgtgtgc tcctattggt gatagtcaca ctgagtacag tttatgtggt tcgtcagcag
    29461 tcggtggcga ttattgaacg ctttgggaaa taccaaaagg ttgccaatag cggtattcat
    29521 attcgcttgc cttttgggat tgactcgatt gcagcacgga ttcagttgcg cttgttgcaa
    29581 agtgatattg tggttgagac taagaccaag gacaatgtgt tcgttatgat gaatgtagcg
    29641 actcagtacc gtgtcaacga gcagagcgtg acagatgctt actataaact catacgtcca
    29701 gaatctcaga ttaaatctta tatcgaagat gctcttcgct cttctgttcc aaaattaacc
    29761 ttggatgaat tgtttgagaa aaaagatgag attgcccttg aagttcaaca ccaagtagca
    29821 gaagaaatga ccacttacgg ctacattatc gtgaaaacct tgattaccaa ggtcgaaccg
    29881 gatgcagaag ttaagcaatc catgaatgaa atcaatgcgg cgcaacgtaa gcgggtcgca
    29941 gcacaagaat tggcggaagc tgacaagatt aaaattgtca ctgcagctga agccgaagca
    30001 gaaaaagacc gccttcatgg tgtggggatt gcccaacaac gtaaggcgat tgtggatgga
    30061 ttggcagagt ctatcaccga actcaaggaa gccaatgttg gcatgacaga agaacaaatc
    30121 atgtctatcc tcttgaccaa ccagtatttg gataccttga atacctttgc ctctaaagga
    30181 aatcaaacca tctttttacc aaatacgcca aatggtgtgg atgatatccg aacacaaatc
    30241 ttgtcagccc ttcgcgctga gaagaaataa tagactaata ctcttcgaaa atctcttcaa
    30301 accacgtcag cgtcgccttg ccgtataga
//
LOCUS       DBEJAU010000026        26667 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC323 isolate 683620
            SAMN38261939-rid24807223.denovo.026, whole genome shotgun sequence.
ACCESSION   DBEJAU010000026 DBEJAU010000000
VERSION     DBEJAU010000026.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261939
            Sequence Read Archive: SRR26833919
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 26667)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 26667)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576303.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576303.1
            Genome Coverage       :: 154x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/19/2025 01:05:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,121
            CDSs (total)                      :: 2,078
            Genes (coding)                    :: 1,943
            CDSs (with protein)               :: 1,943
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 36
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 72 of 135
            Pseudo Genes (incomplete)         :: 63 of 135
            Pseudo Genes (internal stop)      :: 51 of 135
            Pseudo Genes (multiple problems)  :: 46 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..26667
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261939-rid24807223.denovo.026"
                     /strain="GPSC323"
                     /isolate="683620"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            complement(136..528)
                     /locus_tag="ACL29Z_001180"
                     /pseudo
     CDS             complement(136..528)
                     /locus_tag="ACL29Z_001180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002269502.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0004055 - argininosuccinate synthase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006526 - arginine biosynthetic process
                     [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="argininosuccinate synthase domain-containing
                     protein"
     gene            complement(545..1351)
                     /locus_tag="ACL29Z_001181"
     CDS             complement(545..1351)
                     /locus_tag="ACL29Z_001181"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001038484.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HGR0069498.1"
                     /translation="MNKMKKVLMTMFGLVMLPLLFACSNNQSAGIEAIKSKGKLVVAL
                     NPDFAPFEYQKVVDGKNQIVGSDIELAKAIATKLGVELELSPMSFDNVLASVQSGKAD
                     LAISGVSKTDERSKVFDFSIPYYTAKNKLIVKKSDLTTYQSVNDLAQKKVGAQKGSIQ
                     ETMAKDLLQNSSLVSLPKNGNLITDLKSGQVDAVIFEEPVSKGFVENNPDLAIADLNF
                     EKEQDDSYAVAMKKDSKKLKEAVDKTIQKLKESGELDKLIEDAFKASIEK"
     gene            complement(1558..2199)
                     /locus_tag="ACL29Z_001182"
     CDS             complement(1558..2199)
                     /locus_tag="ACL29Z_001182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000571330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGR0069499.1"
                     /translation="MIELKNITKTIGGKVILDNLSLRIDQGDLVAIVGKSGSGKSTLL
                     NLLGLIDGDYSGRYEIFGQTNLAVNSAKSQTIIREHISYLFQNFALIDDETVEYNLML
                     ALKYVKLPKKDKLKKVEEILERVGLSATLHQRVSELSGGEQQRIAVARAILKPSQLIL
                     ADEPTGSLDPENRDLVLKFLLEMNREGKTVIIVTHDAYVAQQCHRIIELGEGK"
     gene            complement(2196..4304)
                     /locus_tag="ACL29Z_001183"
     CDS             complement(2196..4304)
                     /locus_tag="ACL29Z_001183"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000723955.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-associated integral membrane family
                     protein"
                     /protein_id="HGR0069500.1"
                     /translation="MKKISNFCMLLLLLCTTFFVFNVNYTREVVRIQEMGKTVDSLDL
                     YLKDINEPAASVLRFFEDVSKEYKVSIIKTDSGDEVVKSGVFDKDTFPYQEFGISSLD
                     FTTDGEGVYSNKEISNKLGTIPTFLKAKPIQLMTFQTYIKDTSRSLNGRYTITSTQEM
                     DKDRIVQKWSDFFKIDQATLLEPTYKSAVEVINRDLLLSAIVFVLAILLLVLVTVYQP
                     MMEMKRVGVQKLLGFQDRAVLADVVKGNLYLLLGGALVINLGVFFLLDYKPKDLFPML
                     WLSHFLLLQLYLFISWLTYLLIQKMTISSLLKGFSSFKFGLIFNYVMKIGTTILLTAL
                     LIGVGRSLEQENKELAYQQQWVSQGNYLTLETFKLNDNLWQEELAGSGKSTDYFYRFY
                     QDLVEKTQAGYVQSSSLPVKNFVQSEQIQQYQLTDTVDVYYANRNFLKSKGFKLPNTG
                     IKKVILMPASTKGEEDKNQLLGKLIAFHSMKYEEQQKRTIEEMDVEIAYYEGDWSFFP
                     YSDKRKENLSNPIISLVNDSDMMWDEKASLSTTGLNNPIKIENTVQHQKEITELVEKL
                     SDGNYLKFSSIQAIQQEKVDSYRDAVRNFNLLFALFGLLSMMISYFLLVTTFLLKRRD
                     IITKKFMGWKLVDRYRPLLVLLLLGYSFPLLVLIFFAHAFLPLLLFAGFTCLDILFVL
                     GLASRMEKRSLVELLKGGIL"
     gene            complement(4356..4643)
                     /locus_tag="ACL29Z_001184"
     CDS             complement(4356..4643)
                     /locus_tag="ACL29Z_001184"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001230165.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactococcin 972 family bacteriocin"
                     /protein_id="HGR0069501.1"
                     /translation="MRKLVKIGVASLMVCGILATTNALAVWVEGGQWNYGVGWTGTFG
                     YSDYLHSTRYHTATVRHGGRTSKDYAKPEAWARASLTKIPPTGMEYFYGFE"
     gene            5068..5394
                     /locus_tag="ACL29Z_001185"
                     /pseudo
     CDS             5068..5394
                     /locus_tag="ACL29Z_001185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001268160.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
     gene            complement(5446..6033)
                     /locus_tag="ACL29Z_001186"
     CDS             complement(5446..6033)
                     /locus_tag="ACL29Z_001186"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000843467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HGR0069502.1"
                     /translation="MKSITKKIKATLAGVAALFAVFAPSFVSAQESSTYTVKEGDTLS
                     EIAETHNTTVEKLAENNHIDNIHLIYVDQELVIDGPVAPVATPAPATYAAPAAQDETV
                     SAPVAETPVVSETVVSTVSGSEAEAKEWIAQKESGGSYTATNGRYIGRYQLTDSYLNG
                     DYSAENQERVADAYVAGRYGSWTAAKNFWLNNGWY"
     gene            6275..6946
                     /gene="sdaAB"
                     /locus_tag="ACL29Z_001187"
     CDS             6275..6946
                     /gene="sdaAB"
                     /locus_tag="ACL29Z_001187"
                     /EC_number="4.3.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015606087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003941 - L-serine ammonia-lyase activity
                     [Evidence IEA];
                     GO_process: GO:0006094 - gluconeogenesis [Evidence IEA];
                     GO_process: GO:0006565 - L-serine catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="L-serine ammonia-lyase, iron-sulfur-dependent
                     subunit beta"
                     /protein_id="HGR0069503.1"
                     /translation="MKSLRFQSVFDIIGPVMIGPSSSHTAGAVRIGKIVSSIFDDTPT
                     EVEFQLFNSFAKTYRGHGTDLALVAGILGMDTDDPEIPNSLEIAHKRGIKIVWTIQKD
                     SNAPHPNTTKITVKNAHKTISVTGISIGGGNIQVTELNGFAVSLNMNTPTIIIVHQDI
                     PGMIALVTEALSRYGINIAQMNVTREKAGEKAIMIIEVDSRNCDEAIEEIRKIPHLHN
                     VNFFK"
     gene            6955..7827
                     /gene="sdaAA"
                     /locus_tag="ACL29Z_001188"
     CDS             6955..7827
                     /gene="sdaAA"
                     /locus_tag="ACL29Z_001188"
                     /EC_number="4.3.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000500050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003941 - L-serine ammonia-lyase activity
                     [Evidence IEA];
                     GO_process: GO:0006094 - gluconeogenesis [Evidence IEA];
                     GO_process: GO:0006565 - L-serine catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="L-serine ammonia-lyase, iron-sulfur-dependent,
                     subunit alpha"
                     /protein_id="HGR0069504.1"
                     /translation="MFYSIKELVEQADLDFQGNVAELMITTEFELTGREREEVFLLME
                     RNLEVMKASVQLGLNENKSRSGLTGGDAAKLDHYIENGKTLSDYTILSAARNAIAVNE
                     HNAKMGLVCATPTAGSAGCLPSVLTAAIEKLDLSHEQQLDFLFAAGAFGLVIANNASI
                     SGAEGGCQAEVGSASAMSAAALTLAAGGTPYQASQAIAFVIKNMLGLICDPVAGLVEV
                     PCVKRNAMGASFAFIAADMALAGIESKIPVDEVIDAMYQVGASMPTAFRETAEGGLAT
                     TPTGRRLQKEIFGE"
     gene            7849..8481
                     /locus_tag="ACL29Z_001189"
     CDS             7849..8481
                     /locus_tag="ACL29Z_001189"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000200889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HGR0069505.1"
                     /translation="MTSITAIFFDLDGTLVDSSIGIHNAFTYTFKGLGVPSPDAKTIR
                     GFMGPPLESSFATCLSKDQISEAMQIYRSYYKAKGIYEAQLFPQIIDLLEELSSSYPL
                     YITTTKNTSTAQDMAKNLEIHHFFDGIYGSSPEAPHKADVIHQALQTHQLAPEQAIII
                     GDTKFDMLGARETGIQKLAVTWGFGEQADLLNYQPDYIAHKPLEVLAYFQ"
     gene            8531..8701
                     /locus_tag="ACL29Z_001190"
     CDS             8531..8701
                     /locus_tag="ACL29Z_001190"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0069506.1"
                     /translation="MKIKEQTRKLAAGCSKHCFKVVDGTDEVSSKHCFEVVDRTDEVS
                     NIYIRQGDVDVV"
     gene            complement(8787..10637)
                     /locus_tag="ACL29Z_001191"
     CDS             complement(8787..10637)
                     /locus_tag="ACL29Z_001191"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001035735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis protein"
                     /protein_id="HGR0069507.1"
                     /translation="MNKKLTDYVIDLVEILNKQQKQVFWGIFDIFSMVVSIIVSYILF
                     YGLINPAPVDYIIYTSLAFLFYQLMIGFWGLNASISRYSKITDFMKIFFGVTASSVLS
                     YSICYAFLPLFSIRFIILFILLSTFLILLPRITWQLIYSRRKKGSGDGEHRRTFLIGA
                     GDGGALFMDSYQHPTSELELVGILDKDSKKKGQKLGGIPVLGSYDNLPELAKRHQIER
                     VIVAIPSLDPSEYERILQMCNKLGVKCYKMPKVETVVQGLHQAGTGFQKIDITDLLGR
                     QEIRLDESRLGAELTGKTILVTGAGGSIGSEICRQVSRFNPERIVLLGHGENSIYLVY
                     HELIRKFQGIDYVPVIADIQDYDRLLQVFEQYKPAIVYHAAAHKHVPMMERNPKEAFK
                     NNIRGTYNVAKAVDEAKVSKMVMISTDKAVNPPNVMGATKRVAELIVTGFNQRSQSTY
                     CAVRFGNVLGSRGSVIPVFERQIAEGGPVTVTDFRMTRYFMTIPEASRLVIHAGAYAK
                     DGEVFILDMGKPVKIYDLAKKMVLLSGHTESEIPIVEVGIRPGEKLYEELLVSTELVD
                     NQVMDKIFVGKVNVMPLESINQKIGEFRTLSGDELKQAIIAFANQTTHIE"
     gene            complement(10676..11836)
                     /locus_tag="ACL29Z_001192"
     CDS             complement(10676..11836)
                     /locus_tag="ACL29Z_001192"
                     /EC_number="2.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000096190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016757 - glycosyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HGR0069508.1"
                     /translation="MSSKVSGFQDKNGKVLKIMIEWWKEKFRRVVVTQNVESLLVSIV
                     ISAYNEEKYLPGLIEDLKNQTYPKENIEILFINAMSTDGTTAIIQQFIKEDTEFNSIR
                     LYNNPKKNQASGFNLGVKHSVGDLILKIDAHSKVTESFVMNNVAIIQQGEFVCGGPRP
                     TIVEGKGKWAETLHLVEENMFGSSIANYRNSSEDRYVSSIFHGMYKREVFQKVGLVNE
                     QLGRTEDNDIHYRIREHGYKIRYSPSILSYQYIRPTFKKMLHQKYSNGLWIGLTSHVQ
                     FKCLSLFHYVPCLFVLSLVFSLALLPITFVFITLLLGAYFLLLSLLTLLTLLKHKNGF
                     LIVMPFLLFSIHFAYGFGTIVGLIRGFKWKKEYKGTIIYLDKISQINQNMLQ"
     gene            11894..13060
                     /locus_tag="ACL29Z_001193"
     CDS             11894..13060
                     /locus_tag="ACL29Z_001193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CynX/NimT family MFS transporter"
                     /protein_id="HGR0069509.1"
                     /translation="MKKQSLFFVPGIILIGVSLRTPFTVLPIILGNISQGLEVEVSSL
                     GVLTSLPLLMFTLFSPFSTRLAQKIGLEHLFTYSLFFLTIGSLIRLINLPLLYLGTLM
                     VGASVAVINVLLPSLIQANQPKKIGFLTTLYVTSMGIATALASYLAVPITQASSWKGL
                     ILLLTLLCLATFLVWLPNHRYNHRLAPQTKQKSQIKVMRNKQVWAIIIFSGFQSLIFY
                     TVMTWLPTMSIHAGLSSHEAGLLTSILSLISIPFSMTIPSLTTSLSTRNRQLMLTLVS
                     LAGVVGISMLFFPINNFIYWLAIHLLIGTATSALFPYLMVNFSLKTSAPEKTAQLSGL
                     SQTGGYILAAFGPTLFGYSFDLFHSWVPSVAALLLIDILMTVALFTVDRADKIL"
     gene            13199..13525
                     /locus_tag="ACL29Z_001194"
     CDS             13199..13525
                     /locus_tag="ACL29Z_001194"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000273865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HGR0069510.1"
                     /translation="MYFPTSSALIEFLILAVLEQGDSYGYEISQTIKLIANIKESTLY
                     PILKKLEGNSFLTTYSREFQGRMRKYYSLTNGGIEQLLTLKDEWALYTDTINGIIEGS
                     IRHDKN"
     gene            13512..14105
                     /locus_tag="ACL29Z_001195"
     CDS             13512..14105
                     /locus_tag="ACL29Z_001195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000198695.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1700 domain-containing protein"
                     /protein_id="HGR0069511.1"
                     /translation="MTRTEYLTQLELYLKKLPEADRIEAMDYFRELFDDAGVEGEEEL
                     IASLGTPKEAAHEVLFNLLDKKINEAPAQKNNRQILHIALLALLAAPIGIPLGIAILV
                     TLFAILVAALTVILAFFAVSILGIIGGFLFLVESFTILAQAKSAFILIFGSGLLAIGA
                     SSLVLLGISYVARFFGLLIVRLVQFVLKKGKRGNQHA"
     gene            14098..15009
                     /locus_tag="ACL29Z_001196"
     CDS             14098..15009
                     /locus_tag="ACL29Z_001196"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001233690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4097 domain-containing protein"
                     /protein_id="HGR0069512.1"
                     /translation="MRKWTKGFLIFGVVTTVIGFILLFVGIQSDGIKSLLSMSKEPVY
                     DSRTEKLTFGKEVENLEITLHQHALTITDSFDDQIHISYHPSLSAHHDLITNQNDRTL
                     SLTDKKLSETPFLSSGIGGILHIASSYSSRFEEVILQLPKGRTLKGINISANRGQTTI
                     INASLENATLNTNSYILRIEGSRIKNSKLTTPNIVNIFDTVLTDSQLESTENHFHAEN
                     IQVHGKVELTAKDYLRIILDQKESQRINWDISSNYGSIFQFTREKPESRGTELSNPYK
                     TEKTDVKDQLIARSDDNIDLISTPSRR"
     gene            15072..16136
                     /locus_tag="ACL29Z_001197"
     CDS             15072..16136
                     /locus_tag="ACL29Z_001197"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000808437.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF6574 domain-containing protein"
                     /protein_id="HGR0069513.1"
                     /translation="MKQEWFESNDFVKTTSKNKPEEQAQEVADKAEETIADLDTPIEK
                     NTQLEEEVSQAEVELESQQEEKIEAPEDSEARTEIEEKKASNSTEEESDLSKETEKVT
                     IAEESQEALPQQKATTKEPLLISKSLESPYIPDQAPKSRDKWKEQVLDFWSWLVEAIK
                     SPTSKLETSITHSYTAFLLLILFSASSFFFSIYHIKHAYYGHIASINSRFPEQLAPLT
                     LFSIVSILVATTLFFFSFLLGSFVVRRFIHQEKDWTLDKVLQQYSQLLAIPIFLTAIA
                     SFFAFFDSLRFTALLCVISIGIILLASLHIITRPNQASETDSFYQLFLSVLVNGVIIL
                     LFFVAEVALIGDYLRILAFL"
     gene            complement(16207..17067)
                     /locus_tag="ACL29Z_001198"
     CDS             complement(16207..17067)
                     /locus_tag="ACL29Z_001198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001140341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4299 family protein"
                     /protein_id="HGR0069514.1"
                     /translation="MAKTFFIPNKQSILGEQEILNAKSILALLDGLESHSYDVVYLRQ
                     PLNRLEYIECAIVGQSQFLFKVSYADGQKAYRVDLPDLLTKTDWQIIKSFLDALLAYT
                     GTDIEGLDGFDFEAYFQASIQAYLADPVARFTICQGIFNPIFFSRENLKSFLEADGLA
                     QFEARVRAVQETDAYFARVSFYQDGEGKVHGVYHLAQGVKTVLPREPFVPAAYIEQLV
                     DKEVQWEIDLVQITGDGSKPEDYESIARLDYAKFLEVLPPSFYHQLDANQIEVQPILD
                     KDFKTLAQEK"
     gene            complement(17342..18328)
                     /locus_tag="ACL29Z_001199"
     CDS             complement(17342..18328)
                     /locus_tag="ACL29Z_001199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001030014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-related sulfurtransferase"
                     /protein_id="HGR0069515.1"
                     /translation="MAKDIRVLLYYLYTPIENAEQFAADHLAFCKSIGLKGRILVADE
                     GINGTVSGDYETTQKYMDYVHSLPGMEDLWFKIDEESEQAFKKMFVRYKKEIVHLGLE
                     DNDFDNDINPLETTGAYLSPKEFKEALLDKDTVVLDTRNDYEYDLGHFRGAIRPDIRN
                     FRELPQWVRDNKEKFMDKRVVVYCTGGVRCEKFSGWMVREGYKDVGQLHGGIATYGKD
                     PEVQGELWDGKMYVFDERIAVDVNHVNPTIVGKDWFDGTPCERYVNCGNPFCNRRILT
                     SEENEDKYLRGCSHECRVHPRNRYVSKNELTQAEVIERLAAIGESLDQAATV"
     gene            complement(18600..20075)
                     /locus_tag="ACL29Z_001200"
     CDS             complement(18600..20075)
                     /locus_tag="ACL29Z_001200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000800432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HGR0069516.1"
                     /translation="MKNWKKYAFASASVVALAAGLAACGNLTGNSKKAADSGDKPVIK
                     MYQIGDKPDNLDELLANANKIIEEKVGAKLDIQYLGWGDYGKKMSVITSSGENYDIAF
                     ADNYIVNAQKGAYADLTELYKKEGKDLYKALDPAYIKGNTVNGKIYAVPVAANVASSQ
                     NFAFNGTLLAKYGIDISGVTSYETLEPVLKQIKEKAPDVVPFAIGKVFIPSDNFDYPV
                     ANGLPFVIDLEGDTTKVVNRYEVPRFKEHLKTLHKFYEAGYIPKDVATSDTSFDLQQD
                     TWFVREETVGPADYGNSLLSRVANKDIQIKPITNFIKKNQTTQVANFVISNNSKNKEK
                     SMEILNLLNTNPELLNGLVYGPEGKNWEKIEGKENRVRVLDGYKGNTHMGGWNTGNNW
                     ILYINENVTDQQIENSKKELAEAKESPALGFIFNTDNVKSEISAIANTMQQFDTAINT
                     GTVDPDKAIPELMEKLKSEGAYEKVLNEMQKQYDEFLKNKK"
     gene            complement(20333..21256)
                     /locus_tag="ACL29Z_001201"
     CDS             complement(20333..21256)
                     /locus_tag="ACL29Z_001201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001075101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HGR0069517.1"
                     /translation="MAKKKIKKEKIDNVGIHSFSKKADIFFSIISGLIALSCILPFVF
                     VIIISVTDEKSLLQYGYSFFPSQFGLDGFEFLAQFKDKILQALFISVFVTVVGTLTNV
                     FITTTYAYAISRTTFKYRRFFTIFVLLSMLFNAGLVPGYIMVTRVLQLGDTVWALIVP
                     MLLSPFNIILMRSFFKKTIPEAILESARIDGASEARIFFQICLPLSLPGIATITLLTA
                     LGFWNDWFNALLYIKSDNLYPLQYLLMQIQQNMDYIAKAVGLTGQLGVALPKETGRMA
                     MVVVATLPIAILYPFFQRYFVKGLTIGGVKE"
     gene            complement(21270..22199)
                     /locus_tag="ACL29Z_001202"
     CDS             complement(21270..22199)
                     /locus_tag="ACL29Z_001202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000714575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HGR0069518.1"
                     /translation="MKKFSKTLRDNWIFLLMVLPGALWLILFFYIPVFGNVVAFKDYH
                     MTSNGFIDSIINSKWVGLDNFRFLFSSRDAFIITRNTVLYNLGFIFLGLVVSVGIAII
                     LSELRSKRMVKIFQTSMLFPYFLSWVIISFFTDAFLNIDKGVFNHLLESLGLKEVNFY
                     ADLGIWPYLLLFLGIWKGFGYSSVMYYATIMGIDPTYYEAATVDGASKWQRIRNVTIP
                     QLTPLVTVLTILAVGNIFRADFGLFYQIPHNAGQLYNVTNVLDVYVFNGLTQTADIGM
                     AAAAGLYQSVVGLILVILSNLLARRVDPNSALF"
     gene            complement(22518..22739)
                     /locus_tag="ACL29Z_001203"
     CDS             complement(22518..22739)
                     /locus_tag="ACL29Z_001203"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0069519.1"
                     /translation="MSLQIKLKKLAKELSKLLKDSNLETVDKDVLENSQKELQKAVLF
                     LADEKGSEHTEAEVIDNLKEVIAKLKANA"
     gene            complement(22693..22953)
                     /locus_tag="ACL29Z_001204"
     CDS             complement(22693..22953)
                     /locus_tag="ACL29Z_001204"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001810173.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0069520.1"
                     /translation="MTGVSNPTTDSARLVLAEAKKAFADDSLTEQGLRDILQTVKDAI
                     ASLESIKESQSATKDGGQTAGKETAGEDESANQTQEISQGIK"
     gene            23033..23170
                     /locus_tag="ACL29Z_001205"
                     /pseudo
     CDS             23033..23170
                     /locus_tag="ACL29Z_001205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611577.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS630 family transposase"
     gene            complement(23274..23429)
                     /locus_tag="ACL29Z_001206"
                     /pseudo
     CDS             complement(23274..23429)
                     /locus_tag="ACL29Z_001206"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS630 transposase-related protein"
     gene            complement(23615..24226)
                     /gene="rpsD"
                     /locus_tag="ACL29Z_001207"
     CDS             complement(23615..24226)
                     /gene="rpsD"
                     /locus_tag="ACL29Z_001207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015935 - small ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_function: GO:0019843 - rRNA binding [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S4"
                     /protein_id="HGR0069521.1"
                     /translation="MSRYTGPSWKQARRLGLSLTGTGKELARRNYVPGQHGPNNRSKL
                     SEYGLQLAEKQKLRFTYGVGEKQFRNLFVQATKIKGGILGFNFMLLLERRLDNVVYRL
                     GLATTRRQARQFVNHGHILVDGKRVDIPSYRVTPGQVISVREKSLKVPAILEAVEATL
                     GRPAFVSFDAEKLEGSLTRLPERDEINPEINEALVVEFYNKML"
     gene            complement(24421..25473)
                     /locus_tag="ACL29Z_001208"
     CDS             complement(24421..25473)
                     /locus_tag="ACL29Z_001208"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000769768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HGR0069522.1"
                     /translation="MKLKSYILVGYIISTLLTILVVFWAVQKMLIAKGEIYFLLGMTI
                     VASLVGAGISLFLLLPVFTSLGKLKEHAKRVAAKDFPSNLEVQGPVEFQQLGQTFNEM
                     SHDLQVSFDSLEESEREKGLMIAQLSHDIKTPITSIQATVEGILDGIIKESEQAHYLA
                     TIGRQTERLNKLVEELNFLTLNTARNQVETTSKDSIFLDKLLIECMSEFQFLIEQERR
                     DVHLQVIPESARIEGDYAKLSRILVNLVDNAFKYSAPGTKLEVVAKLEKDQLSISVTD
                     EGQGIAPEDLENIFKRLYRVETSRNMKTGGHGLGLAIARELAHQLGGEITVSSQYGLG
                     STFTLVLNLSGSENKA"
     gene            complement(25470..26168)
                     /locus_tag="ACL29Z_001209"
     CDS             complement(25470..26168)
                     /locus_tag="ACL29Z_001209"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000520636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HGR0069523.1"
                     /translation="MGKTILLVDDEVEITDIHQRYLIQAGYQVLVAHDGLEALELFKK
                     KPIDLIITDVMMPRMDGYDLISEVQYLSPEQPFLFITAKTSEQDKIYGLSLGADDFIA
                     KPFSPRELVLRVHNILRRLHRGGETELISLGNLKMNHSSHEVQIGEEMLDLTVKSFEL
                     LWILASNPERVFSKTDLYEKIWKEDYVDDTNTLNVHIHALRQELAKYSSDQTPTIKTV
                     WGLGYKIEKPRGQT"
     gene            complement(26335..>26667)
                     /locus_tag="ACL29Z_001210"
     CDS             complement(26335..>26667)
                     /locus_tag="ACL29Z_001210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000671383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009986 - cell surface [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HGR0069524.1"
                     /translation="INVKETSDTANGSLSPSNSGSGVTPMNHNHATGTTDSMPADTMT
                     SSTNTMAGENMAASANKMSDTMMSEDKAMLPNTGETQTSMASIGFLGLALAGLLGGLG
                     LKNKKEEN"
BASE COUNT         7929 a         5782 c         4876 g         8080 t
ORIGIN      
        1 cccaactcaa ttatgacatt tttttcaaaa gtcaatatat ctcacttttt caacgacaag
       61 aaagaggctg ataatctacc aacctcttat tctgaaccca tcactccatc actttttagc
      121 ttcattcgct ttcttagcga ctgcaatctg gtattcgact tggtcattcc ccttaccggt
      181 acaaccatga gcaattgtag tcgctcctat ctgatgcgct atttcaacca attttttaga
      241 aatcagaggg cggctcaagg cagataccaa gagatacttt tgttcataat aggcatgtga
      301 ctgatgagcc actagcacat aatctgtagc aaattcgtcc ttaacatcaa tgacataaga
      361 ttctactgcc caaaccttaa gagccttatc atggatgaaa tctaagtctt tcccttcacc
      421 cacatccata caaactgaaa caacatcata gtctttcttt aaccaggtaa tagcaactga
      481 tgtgtccaaa ccgccagaat aggccaaaat tactttttct ttactcatgt tcttttcctt
      541 ctttctattt ttcaatggat gctttaaagg catcctcaat gagtttgtct aattccccag
      601 actccttcaa cttttgaatg gttttatcga ctgcctcttt caatttcttg ctatcttttt
      661 tcatggctac cgcgtaggaa tcatcttgct ctttttcaaa attgaggtct gcgattgcta
      721 aatcaggatt attttccaca aatcccttgg aaacaggttc ttcaaagata acggcatcca
      781 cttgtcctga ttttaaatct gtgattaaat tcccattttt aggcagagat acgagggaag
      841 aattttgtag caaatctttc gccatcgtct cttgaatcga acctttctgc gctccaacct
      901 ttttctgcgc caagtcgttt acagactgat aagtagtcaa gtcagatttt ttgacaatga
      961 gtttattttt tgcagtatag tagggaatgg aaaagtcaaa caccttgctc cgttcatctg
     1021 tcttagaaac acctgatatg gcaaggtcgg cttttcctga ttgaacacta gccagtacat
     1081 tatcaaaact catgggagat agttccaatt cgacacctag ttttgttgcg atagccttgg
     1141 ctaattcgat atctgaaccc acaatctgat ttttcccatc aaccactttt tggtattcaa
     1201 atggagcaaa atccggattg agggctacaa ccaattttcc tttggacttg atggcttcaa
     1261 ttccagccga ttgattgttg ctacaagcaa atagtagggg gagcatcact aaaccaaaca
     1321 tcgtcatcaa caccttcttc atcttattca taataaagcc tactttatgt ttattccttt
     1381 tatttgtata aacaatacat ctatatgcat cctttgtcaa gcctaaattg taattttttt
     1441 caatttaaaa cagaaaaacc caggaaaatg acataaaaat atcattccta ggcctattta
     1501 tgctatttct ctctgaaaaa tatgagtatt cagtcggtca aatgaagctg aacgaactca
     1561 ttttccctcg cctaattcaa tgattcgatg acattgttgg gctacataag catcgtgggt
     1621 cacgataatg actgttttcc cctctcgatt catctctaag agaaacttca agaccaaatc
     1681 tctattttca ggatccagag aacctgtcgg ttcatcggct aaaatcagct ggctgggttt
     1741 taagatggct ctagcaactg caattcgttg ttgttcgccc ccagacaact cggagaccct
     1801 ttgatgcaaa gtagctgata aacctactct ctctaaaatc tcttccacct ttttgagctt
     1861 gtctttctta ggcaatttca catatttcag cgccagcatg agattgtact cgaccgtttc
     1921 atcatcaatc agggcaaaat tttgaaacag ataagagata tgttcacgga ttattgtttg
     1981 cgacttagca gaattaaccg ctagatttgt ctgaccaaaa atctcatacc gtccgctata
     2041 atcaccatct atcaaaccca ataaatttaa caaggtcgac ttcccactac cactcttacc
     2101 aacaatagct accaaatccc cctgatcaat cctgagagat aagttatcca aaatcacttt
     2161 tcccccaatg gttttggtaa tatttttcaa ctcaatcata agatgccccc tttcaataac
     2221 tctactagac ttcttttctc catcctagaa gctaagccta gcacaaatag tatatccaga
     2281 catgtaaaac ctgcaaacag tagaagtggt aagaacgcat gggcaaagaa aatcaagact
     2341 agaagaggga aactatagcc cagcaagagc agaacgagga gaggacggta gcgatcgacc
     2401 agtttccacc ccataaactt cttggtaatg atatccctgc gcttcaataa gaaagttgtt
     2461 actagtaaga agtaggaaat catcatgcta aggagaccaa acaaagcaaa gagtaggtta
     2521 aaattccgaa cagcatctcg ataagaatcc actttctctt gttgaatggc ttgaatagat
     2581 gaaaatttta aataatttcc atctgacaat ttctcaacta actctgtaat ctctttttga
     2641 tgttgaaccg tattttcaat tttaatcgga ttatttaagc cagttgttga cagggaggct
     2701 ttctcatccc acatcatatc agaatcattg accaagctaa taattggatt ggagagattt
     2761 tcctttcgct tatcactata tgggaaaaat gaccaatctc cttcataata ggcaatctcg
     2821 acatccatct cctctatcgt tcgtttttgc tgctcttcat acttcatcga atgaaaggca
     2881 attaacttcc ccaagagctg atttttatct tcttcacctt tcgtacttgc tggcatcaaa
     2941 ataacttttt taataccggt atttggtagc ttgaatccct tgctctttag aaaattgcga
     3001 ttggcatagt aaacatccac cgtatctgtt aactgatatt gctgaatctg ttctgattgg
     3061 acaaaatttt ttacaggaag actgctactc tgcacatagc ccgcctgcgt tttttctacc
     3121 aaatcctgat aaaatcgata gaaataatct gtagatttcc ctgaccctgc tagctcttct
     3181 tgccacagat tatcattgag tttgaaggtt tctaaggtca ggtaattacc ttgacttacc
     3241 cactgttgct gataagcaag ttctttgttt tcttgttcta aacttctgcc caccccaatc
     3301 agtaaggccg tcagtaaaat agttgtccct attttcatca cataattgaa gataagacca
     3361 aatttgaaag atgaaaaacc tttcagcaga gagctgattg tcattttttg gattaagagg
     3421 taagtcaacc aactgataaa gagataaagc tgcaacagca aaaaatgaga caaccacagc
     3481 ataggaaaca aatcttttgg cttataatca agcaagaaaa acacgcctag attgatcaca
     3541 agagccccac ctaggaggag gtaaaggttg ccttttacaa catcagctaa aacagcccta
     3601 tcttgaaaac caagtaattt ttgtacccca actcttttca tctccatcat cggttgatac
     3661 actgtcacta acacaagaag caaaatagcc aagacaaaaa caatggcaga taaaagcaaa
     3721 tctcgattta tgacttccac tgcacttttg taggtcggct ctagcaaggt agcctggtct
     3781 atcttgaaaa aatcgctcca tttctgtaca atcctatcct tgtccatctc ttgtgtagaa
     3841 gttatcgtat agcgaccatt taaactacga gatgtatcct tgatataggt ttgaaaagtc
     3901 ataagctgaa taggtttggc ttttagaaag gtcggaatcg taccaagttt attggaaatt
     3961 tctttattac tatagactcc ttcaccatct gtggtaaaat caagagaaga aatcccaaac
     4021 tcttggtagg ggaaggtatc tttatcaaaa acaccagact tgaccacctc atcaccactg
     4081 tctgttttga tgatggagac tttatactcc tttgatacat cctcaaaaaa tcgaagaaca
     4141 gacgctgcag gttcgttaat atctttcaaa tacaaatcca aagaatctac agtctttccc
     4201 atttcttgaa tccgaaccac ttctcgtgta tagtttacat taaaaacaaa aaaagtggta
     4261 cacagaagca ggagtaacat acagaaatta ctgatttttt tcataaaagt gcctccacta
     4321 cagttttccc tctccaaata ggagagggaa gaattttact caaatccata gaaatattcc
     4381 attcctgttg gcggaatctt ggtgagggaa gctctagccc atgcctcagg ttttgcataa
     4441 tccttagagg ttctaccccc atgtctaaca gttgctgtat gatatcgagt agaatgtaag
     4501 taatcagaat atccaaaagt tcctgtccaa cctactccat agttccattg accaccctca
     4561 acccatactg ctaaagcatt tgtagtagca agtataccac ataccattaa agatgcaaca
     4621 ccaattttaa ctaattttct catgatttat ttctcctatt atcgagagct gttccgtaaa
     4681 aacagctata gtaatttatc aacaagtatc gtagtccatt ggactcacct tccttctatc
     4741 tcatttcatt ttttaacaac gaacttactc ttaaccggga gaatggtgcg cttctgtatc
     4801 aggtccttga acaaccagag tagtattaag caaactctaa ctattactca agaatcagtc
     4861 caataaacaa tatggatagc gctttcaaat ttttaaactc ctatcccgtc cttttatcta
     4921 tataataagc ataagcgaaa atataataac tgtcaagtat ctgaagtgaa ttttataaaa
     4981 aaattacaag ccaaatttgt aaagtttaca ctaagccgct agggcaatcg tctatcagaa
     5041 tgtccgttta tttgtcaata atccgagaaa atcttgcaac gcttagaagt ctataaaaac
     5101 tatcaacgtt tatatgactt gcgaatagca atcctgctca acctttccac actctatcta
     5161 tacaatcaag ataaaaacat gtgtaagcaa atctgctata ctttactgga ggacgccaag
     5221 aataagaaaa gctacgatag gctggctatc tgctatgtcc ctattgggat ttgtacagac
     5281 gattctaaac ttatccaaaa agggttctcc cttctggagc taaccgagga aacttctatg
     5341 ctgtctcatc tcaaaaaaga agtagagatc tattaccaag cgaaggaaag ataaaaaagc
     5401 cgagggattt cctcgactct ttacatatta tttgttcgtt agttcttaat accagccatt
     5461 gttaagccag aagtttttag cagcagtcca tgaaccgtaa cgtcctgcaa cgtaggcatc
     5521 tgctacacgt tcttggtttt cagctgagta gtcaccgttc aggtatgaat ctgttaattg
     5581 gtaacgtccg atataacgtc catttgtagc tgtatagcta ccacctgatt ctttttgagc
     5641 gatccattct ttggcttctg cttcagatcc gcttacagtt gaaacaactg tttcacttac
     5701 tactggagtt tctgctactg gagctgaaac agtttcatct tgagcggctg gtgccgcata
     5761 agtagctggc gctggtgttg caacaggcgc tacagggcca tcgataacca actcttgatc
     5821 aacataaatc aaatgaatgt tatcaatgtg gttgttttct gccaattttt caactgttgt
     5881 gttgtgagtt tcagcgattt ctgaaagtgt atcaccttct ttaacagtgt aagttgatga
     5941 ttcttgagca gatacaaatg atggagcaaa tactgcaaac aaggcagcta ctcctgcaag
     6001 agttgcttta atctttttag ttattgattt catattcgaa aattctcctt ctttctatag
     6061 ttctatcata ccctttaaat attaccgttt cttgacactt ttatgtagaa atattacaaa
     6121 attatttttt atttccctaa ataaggtgtt ttttgtcata aaagatacta tttttatgct
     6181 atttgaggta ttagaaaggt tttcatccac aattaaagcc aagcccctca ttctttgata
     6241 taatagagat aagaattttt ataaggggaa actgatgaaa tcacttcgtt ttcaatctgt
     6301 ctttgatatc atcggaccag ttatgattgg cccatctagt agccataccg ctggtgctgt
     6361 tcgtattggg aagattgtct cttccatttt tgatgatact ccgacagaag ttgaattcca
     6421 actttttaac tcatttgcca agacctatcg tggtcacgga acagacctag cccttgttgc
     6481 aggtatttta ggaatggata cagatgatcc tgaaattcca aatagtctgg aaattgccca
     6541 caagcgtggt atcaagattg tctggaccat tcagaaagac agcaatgccc ctcaccctaa
     6601 caccactaaa attactgtta aaaatgccca caagaccatc agcgtgactg gtatttctat
     6661 cggtggagga aatattcagg taaccgaact caatggtttt gccgtctctc tcaatatgaa
     6721 tacaccgact atcatcatcg ttcatcaaga tattccaggt atgattgccc ttgttacaga
     6781 ggcgctttcc cgctatggta tcaatatcgc ccagatgaat gtcactcgtg aaaaagctgg
     6841 tgaaaaagcc attatgatta tcgaagttga cagtcgcaac tgtgatgagg ctatcgaaga
     6901 aattcgaaaa atccctcatc tccacaatgt caatttcttt aaataggagg aagcatgttt
     6961 tattctatca aagaattggt cgagcaagca gatctggact ttcaaggaaa tgtcgcagaa
     7021 ctcatgatta caacagagtt tgaattgacc ggtcgcgaac gtgaagaagt cttccttctc
     7081 atggaacgca atctggaagt tatgaaagcc tctgtccaac ttggcctcaa tgaaaataaa
     7141 tctcgtagtg gcctgacagg tggagatgct gccaaattgg atcactacat cgaaaacgga
     7201 aaaactctgt cagattatac gattctctcg gctgcccgaa atgccatcgc agtcaatgaa
     7261 cacaatgcca aaatgggctt ggtctgtgcc actccaaccg ctggaagtgc tggctgtctg
     7321 ccatccgttc tcactgctgc tattgaaaaa ttagacctca gccacgagca acaattggat
     7381 ttcctctttg ctgctggtgc ctttggacta gtcatcgcaa acaatgcctc catctcaggt
     7441 gctgagggtg ggtgtcaagc tgaagttggt tcagcctctg ctatgagtgc tgccgccttg
     7501 actctggctg caggtggaac accttatcag gccagtcaag ctattgcctt tgtcattaaa
     7561 aatatgctag gcctcatctg tgaccctgtt gcaggtttgg tcgaagttcc ctgtgtcaaa
     7621 cgtaatgcca tgggagctag ctttgctttc atcgcagcag acatggcctt ggcaggtatc
     7681 gaatctaaaa tccctgtgga tgaagtgatc gatgccatgt accaagtagg agcaagcatg
     7741 ccaactgcct ttcgtgaaac agctgaaggt ggactcgcta ccacccctac tggtcgtcgc
     7801 ctccaaaaag aaattttcgg agaataagct tatcaaatag gagaaaccat gacctctatc
     7861 acagcgattt ttttcgattt ggatggaacc ctcgttgata gttctatcgg gattcacaat
     7921 gcctttacct atacctttaa agggctgggg gtgcctagcc ctgatgccaa aactattcgt
     7981 ggttttatgg gaccacctct cgaaagtagt tttgcgacct gcctgtccaa agaccaaatt
     8041 tctgaagcca tgcagatata tcgttcttac tataaggcaa aaggcatcta tgaagctcaa
     8101 ctctttcctc agattataga cttgcttgag gagttatcga gcagttatcc actctacatc
     8161 accacgacaa agaatacatc tactgctcaa gacatggcca aaaacttgga aatccatcat
     8221 ttctttgatg gtatttatgg ttctagccct gaagcacccc ataaggcaga tgtcattcac
     8281 caagccttac agacacatca actagcacca gaacaagcca tcatcatcgg agataccaag
     8341 tttgatatgc tgggagctcg agaaacaggt attcagaaat tggccgtcac ttggggattt
     8401 ggagagcaag cagatctact aaactatcaa cctgattata tcgctcacaa acccttagaa
     8461 gttttggcgt attttcaata gcatagactg ggcgacaact ctatttcaga agaaaatgaa
     8521 gtaatactca atgaaaatca aagagcaaac taggaaacta gctgcgggct gctcaaaaca
     8581 ctgttttaag gttgtagatg gaactgacga agtcagctca aaacactgtt ttgaggttgt
     8641 ggatagaact gacgaagtca gtaacatata catacggcaa ggcgacgttg acgtggtttg
     8701 aagagatttt cgaagagtat aagtctctac ataataaaac gcatattacc aaggttgtgt
     8761 aacttgatac tatgcgtttt tcttttttat tcaatgtggg ttgtttgatt agcaaaggcg
     8821 ataatagctt gcttcaactc atctccactg agagtgcgga actctccaat cttttgattg
     8881 atggattcta aaggcatgac attaacctta ccaacgaaaa tcttatccat aacttgatta
     8941 tcaacgagtt cggttgatac caagagttct tcgtagagtt tttcacctgg gcggattcca
     9001 acttcaacga ttggaatttc actttcagtg tggccactta gaagcaccat cttcttggcc
     9061 aagtcataaa tcttgactgg tttgcccata tcaaggataa agacttcccc atctttggca
     9121 taagcaccag catggataac cagacggcta gcttctggaa tggtcataaa gtaacgggtc
     9181 atgcggaagt ctgtcaccgt tacaggccca ccttcagcaa tctgacgttc aaagactgga
     9241 atgacactac cacggctacc aagaacattc ccaaaacgaa ctgcacagta ggttgattgg
     9301 ctacgttggt taaagccagt gacaatcaac tccgccacgc gcttggttgc tcccataaca
     9361 tttggtggat tgactgcctt atctgtcgaa atcataacca tcttagacac tttagcttca
     9421 tcaacagcct tagcaacatt gtaagttcca cggatattgt ttttgaaggc ttcttttgga
     9481 ttgcgctcca tcataggaac atgcttgtgg gctgccgcat gataaacaat agcaggtttg
     9541 tactgctcaa agacttgcaa caaacgatca tagtcttgaa tgtccgcaat cacaggtaca
     9601 taatcaatcc cttggaactt acgaatcaat tcatgataaa caaggtagat tgagttttcc
     9661 ccatgaccga gtaagacaat gcgttcagga ttgaagcgac taacttgacg acagatttca
     9721 gaaccgattg aacctccagc tcctgtgact aagatggtct tacctgtcag ttctgcaccc
     9781 agacgcgatt cgtcaagacg gatttcctga cgacccaaaa ggtccgtaat atcaattttt
     9841 tggaagccag tacctgcttg gtgaaggccc tgaacaacag tttcaacctt aggcatcttg
     9901 taacatttga cacccagctt attacacatc tgcaagatac gctcatattc tgacggatcc
     9961 agcgacggaa tcgcaacgat gacacgctcg atttgatggc gtttggctaa ttcaggcaga
    10021 ttgtcataag agcccaaaac aggaatacca ccaagttttt gacccttttt cttagaatcc
    10081 ttatccaaaa taccgaccag ttctaattca ctggttggat gttggtaact atccataaag
    10141 agagccccac catcaccggc accaatcaag aaggtccgac ggtgttctcc atcaccacta
    10201 ccttttttgc gtctggagta gattaactgc caagtaatcc gtggcaataa aatcaagaag
    10261 gtactcaaca agataaagag aatgatgaaa cggatggaga agagtggcaa gaaggcataa
    10321 cagatactat atgacaagac actgctagca gtcacaccaa aaaagatttt catgaaatcc
    10381 gtaatcttgc tgtaacgact aatgctcgcg ttcaaccccc aaaaaccaat catcaattga
    10441 tagaacaaga aggccaaact cgtatagata atgtagtcaa caggtgctgg attaatcagc
    10501 ccataaaata aaatataaga tacaatgatg gaaaccacca tactgaaaat atcaaatatt
    10561 ccccagaaaa cctgcttttg ttgtttattt aaaatttcca ccagatcaat cacataatct
    10621 gttagttttt tattcataga aatctactcc tccttaaaag agttttacta tattgttatt
    10681 gtagcatatt ttgatttatt tggcttattt tatccaaata aattattgtt cccttgtact
    10741 ccttcttcca tttaaatcct ctaattaaac ctacaatcgt cccaaagcca taagcaaagt
    10801 gaatggaaaa taaaagaaag ggcatcacaa ttagaaatcc atttttatgt tttaataaag
    10861 tcagcaaagt gagtagtgac aaaagtagaa aataggcacc taatagtaaa gttatgaata
    10921 cgaatgtgat cggtaacaat gctagactaa acacaagact caaaacaaat aaacaaggaa
    10981 catagtgaaa taatgataaa cacttaaact gaacatgact tgtcaagcca atccacaaac
    11041 catttgaata cttttgatgc agcattttct tgaatgttgg tcgaatatac tgataagata
    11101 gaatacttgg gctatagcgg attttataac catgttctcg aattctataa tgaatatcat
    11161 tatcttcagt tcggccaagt tgctcattta ctaaaccaac cttctggaaa acctctcgtt
    11221 tatacatccc atgaaaaata gaagaaacat atctatcctc ggaactattt cgataattgg
    11281 caatgctact gccaaacata ttttcctcaa caagatgcaa ggtctctgcc cattttcctt
    11341 ttccttcgac aatcgtcggt ctaggccccc cacagacaaa ttcaccttgt tgaataatag
    11401 ccacattgtt cattacaaaa ctctcagtaa cttttgaatg agcatcaatt tttaaaataa
    11461 ggtcccctac agaatgttta actcccaggt taaaaccact agcttgattt ttcttaggat
    11521 tgttatacaa tctaattgag ttaaactctg tatcttcctt tataaattgc tgaatgatag
    11581 ctgtggtccc atctgtggac atagcattta taaatagaat ttcaatattc tctttaggat
    11641 aggtttgatt ttttaagtct tcaattagac caggcagata tttttcttca ttgtatgcac
    11701 tgattacaat ggatacgaga agactttcaa cattttgagt cactactact ctcctgaatt
    11761 tttccttcca ccattctatc ataattttca agactttccc atttttatct tgaaagccag
    11821 aaaccttact tgacattata gtgaaaaagc cttaaaataa gctgttatta aaatcagcta
    11881 gaagaggtat tatatgaaaa agcaatcact cttttttgtt ccaggtatta tcctgattgg
    11941 tgtttccttg cgaactcctt ttactgtttt acccattatt ttgggaaata tttcgcaagg
    12001 tctggaggta gaagttagtt cgcttggtgt cttgaccagc ctgcctctcc ttatgtttac
    12061 cctcttttca ccattttcta cccgactggc tcagaaaatc ggcttggagc atctcttcac
    12121 ctacagcctc ttcttcttga ccatcggctc acttattcga ctaatcaatc tgcccctgct
    12181 ctatctagga accttgatgg ttggggcaag tgtcgcagtc atcaatgtcc tgcttcctag
    12241 tcttatccaa gccaatcaac caaagaaaat tggttttctg accaccttat atgtaacgtc
    12301 tatggggatt gcaacggctc tggcttccta tctagctgtg cccattacac aagccagttc
    12361 ttggaaagga cttatccttc tcctcacgtt actctgtcta gcaacttttt tggtctggct
    12421 cccaaatcac cgctataatc atagactagc tccacaaacc aaacaaaaaa gtcaaataaa
    12481 ggtcatgcgt aataaacagg tttgggcaat tattatcttt tcaggttttc aatccttgat
    12541 cttttacacc gtcatgacct ggttacctac catgtctatc catgcaggtc tatccagtca
    12601 cgaagctggc ttgctgactt ctatcttatc tctgattagc attccttttt caatgaccat
    12661 cccaagcctg acaaccagtt tatctactcg caaccgtcag ctcatgctca ctctggtttc
    12721 actagctggt gtggtcggca tttccatgct ctttttccca atcaataatt tcatttactg
    12781 gcttgccatc catctcctca tcggaaccgc aaccagcgcc ctcttccctt atctcatggt
    12841 caacttttca ctcaagacaa gcgcccctga aaagacagcc caattgtccg gcctatctca
    12901 aacaggaggc tatatcctag cagcctttgg gccaaccctc tttggttaca gttttgacct
    12961 gttccactct tgggtaccat ctgtagctgc cctcttgctc atcgatatcc tgatgactgt
    13021 ggccctcttt acagtggaca gagcggataa gatcctttaa acttctagtt ttagctagaa
    13081 gttttttata tataaaaatt ttacacattt ctcttgacag ggctttcttt tagatgtaca
    13141 atgtatgtgt agaaaaatta tatataaaaa tcttacacat tagaaaagga ggtttcccat
    13201 gtactttcca acatcctctg ccttgattga atttctcatc ttggccgtac tggagcaggg
    13261 tgattcttat ggttatgaga ttagccaaac cattaagcta atcgctaata tcaaagaatc
    13321 cacactctat cccattctca aaaaattgga aggcaatagc tttctgacaa cctattctag
    13381 agagttccaa ggtcgcatgc gcaaatacta ctccttgaca aacggtggta tagagcagct
    13441 cttgacccta aaagatgaat gggcactcta tacagacacc atcaatggca tcatagaagg
    13501 gagtatccgc catgacaaga actgaatacc tgactcagct agaactctat ctcaagaaac
    13561 tacctgaagc tgaccgtatc gaagccatgg actatttcag agagctcttt gacgatgctg
    13621 gagtcgaagg agaagaagaa ctcatcgcta gtttgggaac tcccaaagaa gcggcccacg
    13681 aagttctatt caatcttctc gataaaaaaa tcaatgaagc acccgctcaa aaaaataacc
    13741 gacaaatttt acatatcgcc ttgttagccc tccttgcagc acctatcggc attcctctgg
    13801 gaatcgccat cctcgtgacc ctgttcgcaa tccttgtagc cgctttgact gtcattctgg
    13861 ctttctttgc agtttccata ctgggtatca tcggcggatt cctattttta gttgaaagtt
    13921 tcactatcct cgcccaagcc aaatcagcct ttatcttgat ttttggttct ggtttactgg
    13981 ctatcggtgc ttcttcgcta gttttacttg gcatttccta tgtagctcgc ttcttcggtc
    14041 tactcattgt tcgtctggta caatttgttc ttaaaaaagg aaagagaggt aatcagcatg
    14101 cgtaaatgga caaaaggatt tctcatcttt ggtgtggtga ctaccgttat cggctttatc
    14161 ctgctttttg taggtatcca atctgacggg attaagagcc tactttccat gtccaaagaa
    14221 cctgtctatg atagccgtac ggaaaagcta acctttggca aggaagtcga aaacctagaa
    14281 attactctcc accaacacgc gctcaccatc acagactctt tcgatgatca aatccacatt
    14341 tcttaccatc catctctttc tgctcaccat gatcttatca ccaatcagaa cgatagaact
    14401 ctgagtctca ctgataagaa actgtctgaa actccgtttc tctcttctgg aattggtggg
    14461 attcttcata tcgcaagtag ctactctagt cgttttgaag aagttattct ccagctacca
    14521 aaagggagaa ctctaaaagg gatcaacatc tcagccaatc gcggacaaac caccatcata
    14581 aatgctagcc ttgaaaatgc gaccctcaat acaaacagct atatcctccg aattgaagga
    14641 agtcgtatca aaaacagtaa actcacaacg cccaatatcg ttaatatctt tgatacagtt
    14701 cttacagata gtcagctaga gtcaacagag aatcacttcc acgctgaaaa tatccaagtc
    14761 catggcaagg ttgaactgac tgccaaagat tatctcagaa tcatcctaga ccagaaagaa
    14821 agccaacgaa ttaactggga catctcaagc aactatggtt ctatcttcca attcacaaga
    14881 gaaaagcctg aatcaagagg tacggaatta agcaaccctt acaaaactga aaaaaccgat
    14941 gtcaaggatc aactcattgc gagatctgat gataatattg atctaatatc cacaccaagc
    15001 agacgttgac aaaaacgctt acatctgcta ctatggaagc atatttatct aactaaaaag
    15061 gaggttctac catgaaacaa gaatggtttg aaagtaatga ttttgtaaaa acaacaagca
    15121 agaacaagcc tgaagagcaa gctcaagagg ttgcagacaa ggctgaagaa acgatagccg
    15181 atctcgatac accaattgaa aaaaatactc agttagagga ggaagtctct caagctgaag
    15241 tcgaattgga aagccagcaa gaagagaaaa ttgaagctcc tgaagacagt gaagcgagaa
    15301 cagaaataga agaaaagaag gcatctaatt ctactgaaga agagtcagac ctttctaaag
    15361 aaacagaaaa agtcactata gctgaagaga gccaagaagc tcttcctcag caaaaagcaa
    15421 ccacgaaaga gccacttctt atcagtaaat ctttagaaag tccttatatc cccgaccaag
    15481 ctccaaaatc tagggataaa tggaaagagc aagtgcttga tttttggtct tggctagtgg
    15541 aagcgatcaa atctcctaca agtaagttgg aaacaagtat cacacacagt tacacagcct
    15601 ttctcttgct cattctgttt tctgcatctt cctttttctt tagtatctat cacatcaaac
    15661 atgcttacta tggacatata gcaagcatta acagtcgctt ccctgagcag ctagctcctt
    15721 taactctttt ttctatcgtc tctatcctag tagcgacaac actcttcttc ttttcattcc
    15781 tcttgggtag tttcgttgtg agacgattta tccaccagga aaaggactgg acgctagaca
    15841 aggttctcca acaatatagt caactcttgg caattccaat cttcctcact gctattgcta
    15901 gtttctttgc tttctttgat agcctacgat ttacagccct cttgtgtgtg attagcattg
    15961 gaatcattct gcttgccagt ctccatatca ttacaagacc aaatcaagca agtgaaaccg
    16021 actccttcta tcaattattc ttgtctgtcc ttgtgaacgg agttattatc ctcctcttct
    16081 ttgtagctga agtggcactg attggagatt atcttcgtat cttggccttt ctttaaaatt
    16141 caatcctgtc atccttggca ggatttttct atttcaaaaa agcaagtcga ttgacctgct
    16201 tctgctttac ttttcttgtg ctaatgtttt aaaatctttg tctaatatgg gttgcacttc
    16261 tatttgattg gcgtctagtt ggtggtaaaa agatgggggt aatacctcta agaattttgc
    16321 atagtccaag cgagctatgg attcatagtc ttctggttta gagccgtctc ctgtgatttg
    16381 aaccaagtca atctcccact ggacttcctt atccaccaat tgctcaatat aggctgcagg
    16441 aacaaacggt tctctcggta aaactgtctt gactccttga gctagatggt aaacgccatg
    16501 cacttttcct tctccatcct gatagaagga aactctcgca aagtaggcat ctgtctcttg
    16561 aaccgcacgc acacgcgctt caaactgagc caagccatct gcctctaaaa agcttttcaa
    16621 gttctcacga ctaaagaaaa taggattaaa aattccttgg caaatcgtaa aacgagctac
    16681 agggtctgct agataggctt gaatacttgc ttggaaataa gcttcaaaat caaaaccatc
    16741 tagcccttca atatcagtcc ctgtataagc aagcaaagca tctaaaaatg acttgataat
    16801 ctgccagtct gtctttgtta gtaggtcagg aagatcgaca cggtaagcct tttgaccatc
    16861 agcataactg accttaaaga gaaattgtga ttgccccact atcgcacact caatatactc
    16921 gagacgatta agaggctgac ggagatagac tacatcatag ctatgtgact ccaaaccgtc
    16981 tagcaaggcc aagatcgact tggcattcaa aatctcttgt tctcctaaaa tgctctgttt
    17041 atttggaata aaaaatgttt tcgccataac tggactcctt tgaaatcgtt tacatacagt
    17101 ataccttatt tttctgaaag atacaaaaac aaactttata ttcttcgaaa atctcttcaa
    17161 accgcgtcag cttcgccttg ccgtagatat atgtaactga cttcgtcagt cttatctaca
    17221 acctcaaagc agtgctttga gcagcctgcg gctagcttcc tagtttgctc tttgattttc
    17281 attgagtatt agatttttga gtacaaagca tagaaaaaca gcccctaagg actgtttgat
    17341 cttatacagt agctgcctga tccaagcttt caccgatagc ggctaggcgc tcaatcactt
    17401 cagcttgtgt caattcattt tttgaaacat agcggttacg tgggtgaaca cggcactcgt
    17461 gtgagcatcc acgaaggtac ttgtcttcat tttcttctga tgtcaagata cgacggttac
    17521 agaagggatt tccacagtta acataacgtt cacatggtgt tccatcaaac cagtctttcc
    17581 ctacgatggt tgggttgaca tggttgacat caacggcaat acgctcgtca aagacgtaca
    17641 ttttcccatc ccaaagctca ccttgaactt ctgggtcttt accgtaagtt gcgattcctc
    17701 cgtgcaattg gccaacatct ttgtaacctt cacgaaccat ccagcctgag aatttctcac
    17761 agcgaacacc acctgtacag taaaccacga cacgcttgtc catgaatttt tctttgttgt
    17821 cacggaccca ttgtggtaac tcacggaagt tgcgaatatc tgggcgaata gccccacgga
    17881 aatgtcctag gtcgtactca taatcgttac gtgtgtcaag gacaacggta tctttatcaa
    17941 gaagcgcttc tttgaactct tttggagaca agtaagcacc tgttgtttca agtgggttga
    18001 tgtcattgtc aaagtcgttg tcttccaaac caaggtggac aatttctttc ttgtagcgaa
    18061 caaacatctt cttgaaggct tgttcacttt cttcgtcaat cttgaaccag agatcttcca
    18121 ttcctggaag gctgtgaacg tagtccatgt atttttgagt tgtttcatag tcacctgaaa
    18181 ctgttccgtt aattccctcg tcagcgacta ggatacggcc tttaaggccg attgatttac
    18241 agaaagccaa gtggtctgca gcaaattgct ctgcattttc aattggagta taaaggtagt
    18301 aaagtaagac acgaatatct tttgccataa gatttgttct cttttctatt cttaaatttt
    18361 ctaaattttt tatttatcca tactagtata cctgcttgag aaaacgaatg caatttattt
    18421 gactggaaat tgtagaggat tctcgaaatt tcctgaatgg ttaaaataag gacaagagaa
    18481 aacatggata tctatatcct tgtgccaaaa aaaccactgc cctccccaga ccaacctgag
    18541 gaaagcagtg attcttattt taggagttag gaatgaatac acgaaatcaa tttagctgat
    18601 tattttttgt ttttcaagaa ttcatcgtat tgtttttgca tttcgttcaa tactttttcg
    18661 taggcacctt cagatttcaa tttttccatc aattctggaa tagctttatc tgggtctaca
    18721 gtaccagtgt tgatagctgt atcaaattgt tgcattgtgt tagcaatagc tgagatttca
    18781 gatttcacat tgtcagtatt gaagataaat ccaagcgctg gagattcttt agcttctgcc
    18841 aattctttct tagaattttc gatttgttgg tctgtaacgt tttcgttgat gtaaaggatc
    18901 cagttgttac cagtgttcca tccacccatg tgagtgtttc ctttgtagcc atcaagaacg
    18961 cgaacacggt tttctttacc ttcaattttt tcccagttct tgccttctgg accgtaaaca
    19021 agaccgttca agagttctgg attcgtattc aagaggttca agatttccat tgatttttct
    19081 ttgttcttag agttgtttga gatgacaaag ttagcaactt gtgttgtttg gtttttcttg
    19141 atgaagttag taattggttt gatttggata tctttgttgg caacacgtga aagcaagctg
    19201 ttaccgtagt cagctggtcc tactgtttct tcacgaacga accaagtatc ttgttgaagg
    19261 tcaaaggaag tatcgcttgt tgcgacgtct tttggaatgt agccagcttc atagaatttg
    19321 tgaagagtct tcaagtgttc tttgaaacga ggcacttcgt aacggtttac aactttagta
    19381 gtatcgcctt caaggtcgat aacgaatgga agaccgtttg ctactgggta gtcaaagtta
    19441 tcagatggga tgaaaacttt accaatagca aatggtacta cgtctggagc tttttcttta
    19501 atttgtttca agactggctc aagagtttcg taagaagtaa cacctgaaat atcgatacca
    19561 tatttagcaa ggagagttcc gttgaaggca aagttttgag atgatgcaac gttggctgca
    19621 actggaacag cgtaaatctt accatttaca gtattaccct tgatgtaagc tgggtcaagt
    19681 gctttgtaaa ggtctttacc ttcttttttg tacaattctg tcaagtcagc gtaagcacct
    19741 ttttgagcat ttacaatata gttatctgca aaggcaatat catagttttc accagatgat
    19801 gtgataactg acattttctt accatagtca ccccagccaa ggtattggat atccaatttg
    19861 gcaccaactt tttcttcaat gattttgttg gcatttgcta acaattcatc caagttgtct
    19921 ggtttgtcac cgatttggta cattttgata acaggtttgt cacctgaatc agcagctttt
    19981 ttgctgttac ctgtcaaatt tccacaagca gcaagacctg cagccaaagc gactacacta
    20041 gcagatgcaa aagcatattt tttccagttt ttcatgataa aaactccttt ttttattttt
    20101 aaacttataa acaatgtaat gatcttatac tcaatgaaaa tcaaagagca aactagaaaa
    20161 ctagccgcag gctgctcaaa gcactgcttt gaggttgtag ataagactga cgaagtcagt
    20221 tacatatatc tacggcaagg cgacgttgac gcggtttgaa tttgattttc gaagagtatt
    20281 aacttcacac aagggaagtt gggaactgag aaatgttctt tttcaataag cactattctt
    20341 tcacaccacc gatagtcaaa ccttttacaa agtagcgttg gaagaatgga tataaaatcg
    20401 cgattggaag ggttgcaacc acaaccatgg ccatacgacc tgtttctttc ggtagagcaa
    20461 ctcccagttg accagtcaag ccgaccgctt tggcaatgta gtccatattt tgttggattt
    20521 gcatgagcaa atattgcaat ggatacaagt tatcactctt gatgtaaaga agggcgttga
    20581 accagtcatt ccagaaacca agagctgtca aaagcgtgat ggttgcgata cctggtagtg
    20641 acaatggcaa acagatttgg aagaaaatcc gggcctcact ggcaccatcg atacgagccg
    20701 attcgagaat ggcttctgga atggtcttct tgaagaagga acgcatcaag atgatattga
    20761 atggtgagag aagcattgga acaatcaagg cccaaacagt gtcaccaagc tgaagtacac
    20821 gggtcaccat gatataacct ggtaccaaac cagcgttgaa caacatactg agaaggacga
    20881 agatggtaaa aaatctgcga tacttaaagg ttgtccgtga aatagcgtag gcataggttg
    20941 ttgtgataaa gacatttgtc aatgtcccaa ctacggttac aaagacagag atgaagaggg
    21001 cttgtaggat tttatcctta aactgtgcca aaaactcaaa accgtctaag ccaaattggg
    21061 atgggaagaa gctatagccg tattggagga ggcttttctc gtctgtcact gaaataatga
    21121 taacgaatac aaaaggtagg atacaagaga gggcaatcaa acccgaaatg atactgaaga
    21181 agatatctgc tttcttactg aaggagtgaa tgccgacatt atcaattttt tcttttttaa
    21241 ttttcttttt tgccatattc tcctcctttc tagaacaaag ctgagtttgg atcgactcgt
    21301 cttgcaagca agtttgatag gataaccaga atcaaaccaa caacggattg gtaaagaccg
    21361 gctgctgcag ccataccgat atctgctgtc tgagtcaaac cattaaaaac atatacgtcc
    21421 aaaacgttgg ttacattgta aagctgacca gcattgtgtg ggatttgata gaagagaccg
    21481 aagtctgcgc ggaagatatt tccgactgca aggatggtca atacagttac aagcggagtc
    21541 aactgaggaa tggttacgtt gcgaatacgt tgccacttgc tagctccgtc cactgtcgct
    21601 gcttcgtagt aggttggatc aattcccatg atcgtcgcat agtacatgac actgctatat
    21661 ccaaaacctt tccaaatacc taggaaaagt aggagatagg gccagatgcc caggtcagcg
    21721 tagaaattga cttctttgag accaagactt tccaatagat gattgaacac ccctttatca
    21781 atatttagga aggcatctgt aaagaaactg atgataaccc aagacaagaa gtaagggaac
    21841 aacatagaag tttggaaaat cttcaccatt ctcttagaac ggagctcgct gaggataatg
    21901 gcaatcccta cagatacaac taaacctaga aagataaagc caagattgta gaggacagta
    21961 tttcgtgtga taataaaggc gtctcttgaa ctaaataaga atctgaaatt atcgagtccg
    22021 acccatttac tatttatgat actatctatg aaaccattac tggtcatgtg gtagtctttg
    22081 aaggcaacca cgttcccaaa tactggaatg taaaagaata gaatcaacca gagtgcccct
    22141 ggcaaaacca tcaagagaaa gatccagttg tctctcaatg tttttgaaaa ctttttcata
    22201 atttcctccc tttttatttt gatatccatc taaaaattct tttttagact tttgataacg
    22261 attacattat tagtatactc ctatttgcag gttaggttaa actcctaatt atagaaaaaa
    22321 ctccacaaat tatgtagcag atttaaacct ttatcaccac tatcaaacaa atgtcctaaa
    22381 tcaattgttt attttatctc tattagccca gtgatggcgt cactctgtta taagcatcca
    22441 acaacggggt atactgaaaa atctccagac tagggaactc agagatagtt cctaatctgg
    22501 agatttttaa tatgttatta ggcgtttgct ttcaacttag caataacctc tttaagatta
    22561 tcaatcacct ctgcttcagt atgctcagag cctttttcat ctgccaagaa caaaactgct
    22621 ttttgaagtt ctttttgaga gttttcaagg acatccttat ctactgtttc aaggtttgag
    22681 tctttaagaa gtttacttaa ttccttggct aatttcttga gtttgatttg cagactcatc
    22741 ttctcctgct gtttctttgc ccgctgtttg tcctccatcc ttagttgctg actggctttc
    22801 cttaatggac tctagggaag caatggcatc tttgactgtt tgcaagatat cacgtaaacc
    22861 ttgctctgtc aaactatcat ctgcaaaagc tttcttagcc tctgccaaaa ccagacgtgc
    22921 tgaatctgtg gtaggattcg atacacctgt caatgatctc aaaagatttt ctaaggtttg
    22981 agtctgctta ctaatactag actaaaatca aaaagtatta tataacagtg atatgaaatc
    23041 aactaaagaa gaaatccaaa ccatcaaaac acttttaaaa gactctcgta cagctaaata
    23101 tcataaacgc cttcaaatcg ttctattttg tctgatgggc aaatcttata aagagattat
    23161 agaactttta tagtagtttg aaataagatg tgaacatctc tatcaggaaa gtcaaattaa
    23221 tttatagaaa tattttagca gccaaggtgt actgttatag attcaataca ctatacttgg
    23281 tggtttagct ctcctgtttt ctcttttagc tttaaccagc cataaatggt attacgtgag
    23341 atttggaaaa cgtgtgatgc ttctgttata ctacctgttc gctcacaata agagagaact
    23401 tttttacgaa aatctattga atatgccata aaaggattat accacattgt gtactatttt
    23461 tggttcattt tactatatca ctttggacta tatcggtcta gttatgtctc aacgattata
    23521 gctggatact aagagaaatc aaaaaagcac taagggagaa cgtcccaaag tgcttaatat
    23581 caaggcctca aagtctatct tattcaataa aatattacaa cattttgttg tagaattcaa
    23641 cgacaagtgc ttcgttgatt tctgggttga tttcgtcgcg ttctggcaag cgagtcaatg
    23701 aaccttccaa cttttcagcg tcgaatgata cgaatgctgg acgtccaaga gtagcttcta
    23761 ctgcttcaag gattgctgga actttcaatg atttttcacg aactgagatc acttgacctg
    23821 gagttacgcg gtatgatggg atatcaacgc gtttcccgtc aacaaggatg tgaccgtggt
    23881 ttacgaattg acgagcttga cgacgagtag tcgcgagacc aagacggtaa acaacgttat
    23941 ccaaacgacg ttccaaaaga agcataaagt tgaaacctag gattccgcct ttgatttttg
    24001 tagcttgtac gaacaagtta cggaattgtt tttcacctac accgtaagtg aaacgaagtt
    24061 tttgtttttc agccaattgc aaaccgtatt ctgacaattt agaacggttg tttggtccgt
    24121 gttgtcctgg tacgtagtta cgacgtgcca attctttacc tgtacctgta agtgaaaggc
    24181 caaggcgacg agcttgtttc caagatggtc ctgtataacg tgacatatga atgtcctcct
    24241 gatataaata atatttcggt ggaaatagtc acttagaaag ccctgattcg tgcagatgcc
    24301 cttcgcctaa acagccaagg ttacttgtca taagacacct gttgacgagc ttcatgcttt
    24361 cctgctgata tttcacacaa aatctattct accatgaata gctggatttg taaaggggtt
    24421 ttaggcttta ttttcactac cagagaggtt gagaacgagg gtaaaggtac ttcctagacc
    24481 gtactggctg ctgactgtga tttccccacc caattgatgg gccaattcac gcgcaatcgc
    24541 aagtcctaat ccatgaccac ctgtcttcat gttacgcgaa gtttcgacac gataaagacg
    24601 tttgaaaata ttttccaaat cctctggggc aataccctgc ccttcatcgg tcacactgat
    24661 tgaaagctgg tccttctcca gcttagccac cacttccagc ttggttcctg gagcagaata
    24721 tttaaaagcg ttatcgacca gattcaccaa gatacgagaa agcttagcat aatctccctc
    24781 aatccgggca gactctggga ttacctgcaa gtggacatct cttctctcct gctcaatcaa
    24841 aaactgaaat tcactcatgc actcaattaa gagcttgtcc agaaaaatac tgtctttact
    24901 ggtagtttcc acctgattcc tagctgtgtt tagggtcaaa aaattcaact cctcaaccag
    24961 tttattgagc ctctccgtct ggcgtccaat ggttgctaga taatgagctt gctccgactc
    25021 cttgataatc ccatccaaaa tcccttctac cgtcgcttgg atcgaagtga taggagtctt
    25081 aatatcatgc gacaactggg caatcatcaa gcccttttct cgttcgcttt cttccaagga
    25141 atcaaagctt acctgcaaat catgggacat ctcattaaaa gtttgcccta attgctgaaa
    25201 ttctacagga ccttgaacct ccaaatttga aggaaaatcc ttggccgcta cccgcttggc
    25261 atgctccttg agtttgccca acgacgtaaa gactggcaat aggagaaaga gactaatccc
    25321 agcaccgaca aggctggcaa cgatggtcat cccaagcaaa aagtaaatct cgcctttcgc
    25381 aatcagcatt ttttgaacag cccaaaaaac aaccaaaatg gttaagaggg ttgaaataat
    25441 atatccaacc aaaatataac tttttagttt catgtttgtc ctctcggttt ctctatctta
    25501 tatcccaacc cccaaactgt cttaatagtg ggcgtttggt cactactata ttttgccagc
    25561 tcctgtcgaa gagcatggat atgcacattc aaggtattgg tgtcatccac gtagtcttct
    25621 ttccagatct tttcatagag gtctgtcttg gagaaaactc gctctggatt gctagctaaa
    25681 atccacagca attcaaatga tttaacagtt aaatccagca tttcttctcc tatttgaact
    25741 tcatgactac tatgattcat ttttagattg ccaagggaaa tcagctctgt ttcgccccca
    25801 cgatgaaggc ggcgcaaaat attgtggaca cgcaaaacca gctcacgtgg gctaaaaggc
    25861 ttagcaataa aatcatctgc tcccaagctc agaccgtaaa tcttgtcctg ttcactggtc
    25921 ttagcagtaa taaataggaa aggctgctct ggtgataagt attgaacctc actgattaaa
    25981 tcataaccat ccatccgagg catcatgaca tctgtgataa tcaaatcaat cggttttttc
    26041 ttgaacagct ctagcgcttc cagtccatca tgggctacca agacctgata acctgcctga
    26101 attaagtatc tctgatgaat atctgtgatt tctacctcgt cgtcaacgag taaaattgtc
    26161 tttcccatct gtctctcctt tgataaaaac agtgctatac tgctttaagt ataacactat
    26221 ttttattgtt ttacgatgat tttaatctgc tattgaaaga aagtcctgat tgctgattga
    26281 gttgttaaac taatcttagt cagcccacta tccatcattt atttccttag ctgattagtt
    26341 ttcttctttt ttgtttttca aacctagacc accgagtaaa cctgcaagcg caagcccaag
    26401 gaaaccaata cttgccattg atgtttgagt ctcaccagta tttggtagca tagctttatc
    26461 ctctgacatc atcgtatcag acatcttgtt agcagaagca gccatgtttt cacctgccat
    26521 cgtgttggta gaacttgtca tggtgtcagc aggcatgcta tctgtagtac ctgtagcatg
    26581 attgtgattc atcggagtca cgccagaacc agagttagaa ggtgataatg aaccatttgc
    26641 tgtgtctgat gtttctttaa catttat
//
LOCUS       DBEJAU010000027        26434 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC323 isolate 683620
            SAMN38261939-rid24807223.denovo.027, whole genome shotgun sequence.
ACCESSION   DBEJAU010000027 DBEJAU010000000
VERSION     DBEJAU010000027.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261939
            Sequence Read Archive: SRR26833919
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 26434)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 26434)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576303.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576303.1
            Genome Coverage       :: 154x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/19/2025 01:05:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,121
            CDSs (total)                      :: 2,078
            Genes (coding)                    :: 1,943
            CDSs (with protein)               :: 1,943
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 36
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 72 of 135
            Pseudo Genes (incomplete)         :: 63 of 135
            Pseudo Genes (internal stop)      :: 51 of 135
            Pseudo Genes (multiple problems)  :: 46 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..26434
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261939-rid24807223.denovo.027"
                     /strain="GPSC323"
                     /isolate="683620"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            <1..990
                     /gene="lytB"
                     /locus_tag="ACL29Z_001211"
     CDS             <1..990
                     /gene="lytB"
                     /locus_tag="ACL29Z_001211"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010976495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endo-beta-N-acetylglucosaminidase"
                     /protein_id="HGR0069525.1"
                     /translation="LKSDGKMAEKEWVYDSHSQAWYYFKSGGYMAKNETVDGYQLGSD
                     GKWLGGKATNKNAAYYQVVPVTANVYDSDGEKLSYISQGSVVWLDKDRKSDDKRLAIT
                     ISGLSGYMKTEDLQALDASKDFIPYYESDGHRFYHYVAQNASIPVASHLSDMEVGKKY
                     YSADGLHFDGFKLENPFLFKDLTEATNYSVEELDKVFSLLNINNSLLENKGATFKEAE
                     EHYHINALYLLAHSALESNWGRSKIAKDKNNFFGITAYDTTPYLSAKTFDDVDKGILG
                     ATKWIKENYIDRGRTFLGNKASGMNVEYASDPYWGEKIASVMMKINEKLGGKD"
     gene            complement(1051..2706)
                     /gene="pavA"
                     /locus_tag="ACL29Z_001212"
     CDS             complement(1051..2706)
                     /gene="pavA"
                     /locus_tag="ACL29Z_001212"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_094859469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rqc2 family fibronectin-binding protein PavA"
                     /protein_id="HGR0069526.1"
                     /translation="MSFDGFFLHHIVEELRSELVNGRIQKINQPFEQELVLQIRSNRQ
                     SHRLLLSAHPVFGRIQLTQTTFENPAQPSTFIMVLRKYLQGALIESIEQVENDRIVEI
                     TVSNKNEIGDHIQATLIIEIMGKHSNILLVDKSSHKIIEVIKHVGFSQNSYRTLLPGS
                     TYIAPPSTESLNPFTIKDEKLFEILQTQELTAKNLQSLFQGLGRDTANELERILVSEK
                     LSAFRNFFNQETKPCLTKTSFSPVPFANQVGEPFANLSDLLDTYYKDKAERDRVKQQA
                     SELIRRVENELQKNRHKLKKQEKELLATDNAEEFRQKGELLTTFLHQVPNDQDQVILD
                     NYYTNQPIMIALDKALTPNQNAQRYFKRYQKLKEAVKYLTDLIEETKATILYLESVET
                     VLNQAGLEEIAEIREELIQTGFIRRRQREKIQKRKKLEQYLASDGKTIIYVGRNNLQN
                     EELTFKMARKEELWFHAKDIPGSHVVISGNLDPSDAVKTDAAELAAYFSQGRLSNLVQ
                     VDMIEVKKLNKPTGGKPGFVTYTGQKTLRVTPDSKKIASMKKS"
     gene            2811..3308
                     /gene="ybeY"
                     /locus_tag="ACL29Z_001213"
     CDS             2811..3308
                     /gene="ybeY"
                     /locus_tag="ACL29Z_001213"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018380869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004540 - RNA nuclease activity [Evidence
                     IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0042254 - ribosome biogenesis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA maturation RNase YbeY"
                     /protein_id="HGR0069527.1"
                     /translation="MYIEMVDETGQVSKEMLQQTQEILEFAAQKLGKEDKEMAVTFVT
                     NERSHELNLEYRDTDRPTDVISLEYKPELEIAFDEEDLLENPELAEMMSEFDAYIGEL
                     FISIDKAHEQAEEYGHSFEREMGFLAVHGFLHINGYDHYTPEEEAEMFGLQEEILTAY
                     GLTRQ"
     gene            3289..3684
                     /locus_tag="ACL29Z_001214"
     CDS             3289..3684
                     /locus_tag="ACL29Z_001214"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000378166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016301 - kinase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase family protein"
                     /protein_id="HGR0069528.1"
                     /translation="MDSQDNKRKWKNRDLISSLEFALTGIFTAIKEERNMRKHAVTAL
                     VVILAGFVFQVSRIEWLFLLLNIFLVVAFEIINSAIENVVDLASHYHFSMLAKNAKDM
                     AAGAVLVVSLFAALTGALIFLPRIWDLLF"
     gene            3701..4600
                     /gene="era"
                     /locus_tag="ACL29Z_001215"
     CDS             3701..4600
                     /gene="era"
                     /locus_tag="ACL29Z_001215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002935752.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase Era"
                     /protein_id="HGR0069529.1"
                     /translation="MTFKSGFVAILGRPNVGKSTFLNHVMGQKIAIMSDKAQTTRNKI
                     MGIYTTDKEQIVFIDTPGIHKPKTALGDFMVESAYSTLREVDTVLFMVPADEARGKGD
                     DMIIERLKAAKVPVILVVNKIDKVHPDQLLSQIDDFRNQMDFKEIVPISALQGNNVSR
                     LVDILSENLDEGFQYFPSDQITDHPERFLVSEMVREKVLHLTREEIPHSVAVVVDSMK
                     RDEETDKVHIRATIMVERDSQKGIIIGKGGAMLKKIGSMARRDIELMLGDKVFLETWV
                     KVKKNWRDKKLDLADFGYNEREY"
     gene            4649..5473
                     /gene="mutM"
                     /locus_tag="ACL29Z_001216"
     CDS             4649..5473
                     /gene="mutM"
                     /locus_tag="ACL29Z_001216"
                     /EC_number="3.2.2.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001114577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0008534 - oxidized purine nucleobase
                     lesion DNA N-glycosylase activity [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-formamidopyrimidine glycosylase"
                     /protein_id="HGR0069530.1"
                     /translation="MPELPEVETVCRGLEKLIIGKKISSIEIRYPKMIKTDLEEFQRE
                     LPSQIIESMGRRGKYLLFYLTDKVLISHLRMEGKYFYYPDQGPERKHAHVFFHFEDGG
                     TLVYEDVRKFGTMELLVPDLLDAYFISKKLGPEPSEQDFDLQVFQAALAKSKKPIKSH
                     LLDQTLVAGLGNIYVDEVLWRAQVHPARPSQTLTAEEATAIHDQTIAVLGQAVEKGGS
                     TIRTYTNAFGEDGSMQDFHQVYDKTGQECVRCGTIIEKIQLGGRGTHFCPNCQRRD"
     gene            5473..6078
                     /gene="coaE"
                     /locus_tag="ACL29Z_001217"
     CDS             5473..6078
                     /gene="coaE"
                     /locus_tag="ACL29Z_001217"
                     /EC_number="2.7.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004259526.1"
                     /note="Dephospho-CoA kinase (CoaE) performs the final step
                     in coenzyme A biosynthesis; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004140 - dephospho-CoA kinase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0015937 - coenzyme A biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dephospho-CoA kinase"
                     /protein_id="HGR0069531.1"
                     /translation="MGKIIGITGGIASGKSTVTNFLRQQGFQVVDADAVVHQLQKPGG
                     RLFEALVQHFWQEIILENGELNRPLLASLIFSNPDEREWSKQIQGEIIREELATLREQ
                     LAQTEEIFFMDIPLLFEQDYSDWFAETWLVYVDRDAQVERLMKRDQLSKDEAESRLAA
                     QWPLEKKKDLASQVLDNNGNQNQLLNQVHILLEGGRQDDRD"
     gene            6065..7264
                     /locus_tag="ACL29Z_001218"
     CDS             6065..7264
                     /locus_tag="ACL29Z_001218"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000136121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MFS transporter"
                     /protein_id="HGR0069532.1"
                     /translation="MTEINWKDNLRIAWFGNFLTGASISLVVPFMPIFVENLGVGSEQ
                     VAFYAGLAISVSAISAALFSPIWGILADKYGRKPMMIRAGLAMTITMGGLAFVPNIYW
                     LIFLRLLNGVFAGFVPNATALIASQVPKEKSGSALGTLSTGVVAGTLTGPFIGGFIAE
                     LFGIRTVFLLVGSFLFLAAILTICFIKEDFQPVAKEKAIPTKELFTSVKYPYLLLNLF
                     LTSFVIQFSAQSIGPILALYVRDLGQTENLLFVSGLIVSSMGFSSMMSAGVMGKLGDK
                     VGNHRLLVVAQFYSVIIYLLCANASSPLQLGLYRFLFGLGTGALIPGVNALLSKMTPK
                     AGISRVFAFNQVFFYLGGVVGPMAGSAVAGQFGYHAVFYATSLCVAFSCLFNLIQFRT
                     LLKVKEI"
     gene            7264..7413
                     /gene="rpmG"
                     /locus_tag="ACL29Z_001219"
     CDS             7264..7413
                     /gene="rpmG"
                     /locus_tag="ACL29Z_001219"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HGR0069533.1"
                     /translation="MRVKINLKCSSCGSINYLTSKNSKTHPDKIEVLKYCPKERKVTL
                     HLESK"
     gene            7453..7686
                     /gene="secG"
                     /locus_tag="ACL29Z_001220"
     CDS             7453..7686
                     /gene="secG"
                     /locus_tag="ACL29Z_001220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012000186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015136 - sialic acid transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0015739 - sialic acid transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecG"
                     /protein_id="HGR0069534.1"
                     /translation="MYNLLLTILLVLSVVIVIAIFMQPTKNQSSNVFDASSGDLFERS
                     KARGFEAVMQRLTGILVFFWLAIALALTVLSSR"
     gene            7788..10142
                     /gene="rnr"
                     /locus_tag="ACL29Z_001221"
     CDS             7788..10142
                     /gene="rnr"
                     /locus_tag="ACL29Z_001221"
                     /EC_number="3.1.13.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000653285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0004518 - nuclease activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease R"
                     /protein_id="HGR0069535.1"
                     /translation="MKDRIKEYLQDKGKVTVNDLAQALGKDSSKDFRELIKTLSLMER
                     KHQIRFEEDGSLTLEIKKKHEITLKGIFHAHKNGFGFVSLEGEEDDLFVGKNDVNYAI
                     DGDTVEVVIKKVADRNKGTAAEAKIIDILEHSLTTVVGQIVLDQEKPKYAGYIRSKNQ
                     KISQPIYVKKPALKLEGTEVLKVFIDKYPSKKHDFFVASVLDVVGHSTDVGIDVLEVL
                     ESMDIVSEFPEAVVKEAESVPDAPSQKDMEGRLDLRDEITFTIDGADAKDLDDAVHIK
                     ALKNGNLELGVHIADVSYYVTEGSALDKEALNRATSVYVTDRVVPMLPERLSNGICSL
                     NPQVDRLTQSAIMEIDKHGRVVNYTITQTVIKTSFRMTYSDANDILAGDEEKRKKYHK
                     IVPSIELMAKLHETLENMRVKRGALNFDTNEAKILVDKQGKPVDIVLRQRGIAERMIE
                     SFMLMANETVAEHFSKLDLPFIYRIHEEPKAEKVQKFIDYASSFGLRIYGTASEISQE
                     ALQDIMRAVEGEPYADVLSMMLLRSMQQARYSEHNHGHYGLAADYYTHFTSPIRRYPD
                     LLVHRMIRDYGCSKEIAEHFEQVIPEIATQSSNRERRAIEAEREVEAMKKAEYMEEYV
                     GEEYDAVVSSIVKFGLFVELPNTVEGLIHITNLPEFYHFNERDLTLRGEKSGITFRVG
                     QQIRIRVERADKMTGEIDFSFVPSEFDVIEKGLKQSSRSGRGRGSNRRSDKKEDKRKL
                     GRSNDKRKHSQKDKKKKGKKPFYKEVAKKGAKHGKGRGKGRRTK"
     gene            10105..10572
                     /gene="smpB"
                     /locus_tag="ACL29Z_001222"
     CDS             10105..10572
                     /gene="smpB"
                     /locus_tag="ACL29Z_001222"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002894882.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SsrA-binding protein SmpB"
                     /protein_id="HGR0069536.1"
                     /translation="MAKGEGKVVAQNKKARHDYTIVDTLEAGMVLTGTEIKSVRAARI
                     NLKDGFAQVKNGEVWLSNVHIAPYEEGNIWNQEPERRRKLLLHKKQIQKLEQETKGTG
                     MTLVPLKVYIKDGYAKLLLGLAKGKHDYDKRESIKRREQNRDIARVMKAVNQR"
     gene            10588..11448
                     /gene="tehB"
                     /locus_tag="ACL29Z_001223"
     CDS             10588..11448
                     /gene="tehB"
                     /locus_tag="ACL29Z_001223"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000413836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008757 - S-adenosylmethionine-dependent
                     methyltransferase activity [Evidence IEA];
                     GO_process: GO:0046690 - response to tellurium ion
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SAM-dependent methyltransferase TehB"
                     /protein_id="HGR0069537.1"
                     /translation="MEKLVAYKRMPLWNKQTMPEAVQQKHNTKVGTWGKITVLKGALK
                     FIELTEEGEVLAEHLFEAGADNPMAQPQAWHRVEAATDDVEWYLEFYCKPEDYFAKKY
                     NTNPVHSEVLEAMQTVKQGKALDLGCGQGRNSLFLAQQDFDVTAVDQNGLALEILQSI
                     VEQEDLDMPVGLYDINSASIEQEYDFIVSTVVLMFLQADRIPAIIQNMQEKTSVGGYN
                     LIVCAMDTEDYPCSVNFPFTFKEGELADYYKDWELVKYNENPGHLHRRDENGNRIQLR
                     FATLLAKKIK"
     gene            11521..12471
                     /locus_tag="ACL29Z_001224"
                     /pseudo
     CDS             11521..12471
                     /locus_tag="ACL29Z_001224"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000495911.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="competence protein CoiA"
     gene            12493..14295
                     /gene="pepF"
                     /locus_tag="ACL29Z_001225"
     CDS             12493..14295
                     /gene="pepF"
                     /locus_tag="ACL29Z_001225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004252660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004222 - metalloendopeptidase activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="oligoendopeptidase F"
                     /protein_id="HGR0069538.1"
                     /translation="MVLQRNEINEKDTWDLSTIYPTDQAWEEALKDLTEQLETVAQYE
                     GHLLDSADNLLEITEFSLEMERQMEKLYVYAHMKNDQDTREAKYQEYYAKAMTLYSQL
                     DQAFSFYDPEFMEISEKQYADFLEAQPKLQVYQHYFDKLLKGKDHVLSQREEELLAGA
                     GEIFGSASETFAILDNADIVFPYVLDDDGKEVQLSHGTYTRLMESKKREVRRGAYQAL
                     YATYEQFQHTYAKTLQTNVKVQNYRAKVRNYKSARHAALAANFVPESVYDNLVAAVRK
                     HLPLLHRYLELRSKILGISDLKMYDVYTPLSSVEYSFTYQEALKKAEDALAVLGEDYL
                     SRVKRAFSERWIDVYENQGKRSGAYSGGSYDTNAFMLLNWQDNLDNLFTLVHETGHSM
                     HSSYTRETQPYVYGDYSIFLAEIASTTNENILTEKLLEEVEDDATRFAILNNFLDGFR
                     GTVFRQTQFAEFEHAIHQADQNGEVLTSDFLNKLYADLNQEYYGLSKEDNPEIQYEWA
                     RIPHFYYNYYVYQYSTGFAAASALAEKIVHGSQEDRDRYIDYLKAGKSDYPLNVMRKA
                     GVDMEKEDYLNDAFAVFERRLNEFEALVEKLGLA"
     gene            14297..15010
                     /locus_tag="ACL29Z_001226"
     CDS             14297..15010
                     /locus_tag="ACL29Z_001226"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812425.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008757 - S-adenosylmethionine-dependent
                     methyltransferase activity [Evidence IEA];
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA];
                     GO_process: GO:0032259 - methylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="O-methyltransferase"
                     /protein_id="HGR0069539.1"
                     /translation="MVESYSKNANHNMRRPVVKEEIVDLMRQRQKQVTGFLKELEDFA
                     RKENIPIIPHETVAYFRFLMETMQPKNILEIGTAIGFSALLMAEHAPNAKITTIDRNP
                     EMIGFAKENFAQFDSRKQITLLEGDAVDVLSTLTESYDFVFMDSAKSKYIVFLPEILK
                     HLEVGGVVVLDDIFQGGDVAKDIMEVRRGQRTIYRGLQKLFDATLDNPELTATLVPLG
                     DGILMLRKNVADVQLSESE"
     gene            15077..16018
                     /gene="prsA"
                     /locus_tag="ACL29Z_001227"
     CDS             15077..16018
                     /gene="prsA"
                     /locus_tag="ACL29Z_001227"
                     /EC_number="5.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase PrsA"
                     /protein_id="HGR0069540.1"
                     /translation="MKKKLLAGAITLLSVATLAACSKGSEGADLISMKGDVITEHQFY
                     EQVKNNPSAQQVLLNMTIQKVFEKQYGSELDDKEVDDTIAEEKKQYGENYQRVLSQAG
                     MTLETRKAQIRTSKLVELAVKKVAEAELTDEAYKKAFDEYTPDVTAQIIRLNNEDKAK
                     EVLEKAKAEGADFAQLAKDNSTDEKTKENGGEITFDSASTEVPEQVKKAAFALDVDGV
                     SDVITATGTQAYSSQYYIVKLTKKTEKSSNIDDYKEKLKTVILTQKQNDSTFVQSIIG
                     KELQAANIKVKDQAFQNIFTQYIGGGDSSSSSSTSNE"
     gene            complement(16135..16476)
                     /locus_tag="ACL29Z_001228"
                     /pseudo
     CDS             complement(16135..16476)
                     /locus_tag="ACL29Z_001228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611512.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            16889..16984
                     /locus_tag="ACL29Z_001229"
                     /pseudo
     CDS             16889..16984
                     /locus_tag="ACL29Z_001229"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS630 family transposase"
     gene            complement(17237..17857)
                     /locus_tag="ACL29Z_001230"
     CDS             complement(17237..17857)
                     /locus_tag="ACL29Z_001230"
                     /EC_number="3.1.3.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000780815.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HGR0069541.1"
                     /translation="MKLYFVRHGRTLWNQEGRFQGASGDSPLLPESIETLKRLGQYLK
                     EIPFDQIYSSDLPRAVKSAEIIQIQLHTPCSLEIVPNLREWQLGKLEGLKIATLEAIY
                     PQQIQAFRSNLAQFDTRMFGAESLYSTTQRTIQFIKSLKDSPAERILIVGHGANLTAS
                     LRTLLGYKEPLLRKDGGLANASLTIIETHDFETFTLNTWNDTSYQS"
     gene            complement(17857..18339)
                     /locus_tag="ACL29Z_001231"
     CDS             complement(17857..18339)
                     /locus_tag="ACL29Z_001231"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397917.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016829 - lyase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aminoacyl-tRNA deacylase"
                     /protein_id="HGR0069542.1"
                     /translation="MAKKVKIKKTLVEQILSKAAIPHQGIQINALEGELPQGYERDQI
                     FKTLALLGDKTGPIIGIVPITQHLSEKKLAKISGNKKVSMIPQKDLEKTTGYIHGANN
                     PVGIRQKHNYPIFIDKIALGLDQMIVSAGEVGHSIIVAPQDLASFVKADFVDILEDIK
                     "
     gene            complement(18339..19181)
                     /locus_tag="ACL29Z_001232"
     CDS             complement(18339..19181)
                     /locus_tag="ACL29Z_001232"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004256605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF368 domain-containing protein"
                     /protein_id="HGR0069543.1"
                     /translation="MLSWLARVIKGIVIALGFILPGISGGVLAAILGIYERMIGFLAH
                     PFKDLKENVLYFIPVAIGMLLGIGLFSYPIEYLLENYQVFVLWSFAGAIIGTVPSLLK
                     ESTRESDRDKIDLAWLWTTFIISGLGLYALNFVVGTLSASFLNFVLAGALLALGVLVP
                     GLSPSNLLLILGLYAPMLTGFKTFDLLGTFFPIGIGAGATLIVFSKLMDYALNNYHSR
                     VYHFIIGIVLSSTLLILIPNAGNAESIQYTGLSLVGYVIIAFFFALGIWLGIWMSQLE
                     DKYK"
     gene            complement(19276..20076)
                     /locus_tag="ACL29Z_001233"
     CDS             complement(19276..20076)
                     /locus_tag="ACL29Z_001233"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 25 protein"
                     /protein_id="HGR0069544.1"
                     /translation="MRKQIHPLILFSFLGIMMFILIINRPLNDSQSFKTKSNIAQIEA
                     QALKHLDKPIIDLSGWQRPEEINYDALSQNISGAIVRVHSGAQTTKENDASFINGIDK
                     AYKSHITELQKRNVPVAVYAYVAGKSAQEMEKAAEVFYNAASPYSPSYYWLDVEDKTM
                     SNMNEGVENFRAKLASLGAKNIGIYVGVYFMEEHSIDTGKFTSVWIPSYGSDSGFLES
                     SPKTDLDYDIHQYTSKGKIAGFDHDLDINVISPLKNKEETFRKLFLKP"
     gene            20220..21599
                     /gene="glmU"
                     /locus_tag="ACL29Z_001234"
     CDS             20220..21599
                     /gene="glmU"
                     /locus_tag="ACL29Z_001234"
                     /EC_number="2.3.1.157"
                     /EC_number="2.7.7.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002899862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000287 - magnesium ion binding [Evidence
                     IEA];
                     GO_function: GO:0003977 - UDP-N-acetylglucosamine
                     diphosphorylase activity [Evidence IEA];
                     GO_function: GO:0019134 - glucosamine-1-phosphate
                     N-acetyltransferase activity [Evidence IEA];
                     GO_process: GO:0006048 - UDP-N-acetylglucosamine
                     biosynthetic process [Evidence IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional UDP-N-acetylglucosamine
                     diphosphorylase/glucosamine-1-phosphate
                     N-acetyltransferase GlmU"
                     /protein_id="HGR0069545.1"
                     /translation="MSNFAIILAAGKGTRMKSDLPKVLHKVAGISMLEHVFRSVGAIQ
                     PEKTVTVVGHKAELVEEVLAGQTEFVTQSEQLGTGHAVMMTEPILEGLSGHTLVIAGD
                     TPLITGESLKNLIDFHINHKNVATILTAETDNPFGYGRIVRNDNAEVLRIVEQKDATD
                     FEKQIKEINTGTYVFDNERLFEALKNINTNNAQGEYYITDVIGIFRETGEKVGAYTLK
                     DFDESLGVNDRVALATAESVMRRRINHKHMVNGVSFVNPEATYIDIDVEIAPEVQIEA
                     NVTLKGQTKIGAETVLTNGTYVVDSTIGAGAVITNSMIEESSVADGVTVGPYAHIRPN
                     SSLGAQVHIGNFVEVKGSSIGENTKAGHLTYIGNCEVGSNVNFGAGTITVNYDGKNKY
                     KTVIGDNVFVGSNSTIIAPVELGDNSLVGAGSTITKDVPADAIAIGRGRQINKDEYAT
                     RLPHHPKNQ"
     gene            21609..22154
                     /locus_tag="ACL29Z_001235"
     CDS             21609..22154
                     /locus_tag="ACL29Z_001235"
                     /EC_number="3.6.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000393791.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HGR0069546.1"
                     /translation="MEFEEKTLSRKEIYQGPIFKLVQDQVELPEGKGTAQRDLIFHNG
                     AVCVLAVTDEQKLILVKQYRKAIEAVSYEIPAGKLEVGENTAPVAAALRELEEETAYT
                     GKLELLYDFYSAIGFCNEKLKLYLASDLTKVENPRPQDEDETLEVLEVSLEEAKELIQ
                     SGHICDAKTIMAVQYWELKKK"
     gene            22166..22480
                     /gene="macP"
                     /locus_tag="ACL29Z_001236"
     CDS             22166..22480
                     /gene="macP"
                     /locus_tag="ACL29Z_001236"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000517865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall synthase accessory phosphoprotein
                     MacP"
                     /protein_id="HGR0069547.1"
                     /translation="MGKSLLTDEMIERANRGEKISGPPLLDDNEETKILPTSSSRFGY
                     ANPKNHGFSQETLKIQVEPSIHKSRRIENTKRNVFNSKLNKILFAVIFLLILLVLAMK
                     LL"
     gene            22497..23189
                     /locus_tag="ACL29Z_001237"
     CDS             22497..23189
                     /locus_tag="ACL29Z_001237"
                     /EC_number="3.2.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004261401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008782 - adenosylhomocysteine
                     nucleosidase activity [Evidence IEA];
                     GO_function: GO:0008930 - methylthioadenosine nucleosidase
                     activity [Evidence IEA];
                     GO_process: GO:0009116 - nucleoside metabolic process
                     [Evidence IEA];
                     GO_process: GO:0009164 - nucleoside catabolic process
                     [Evidence IEA];
                     GO_process: GO:0019509 - L-methionine salvage from
                     methylthioadenosine [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="5'-methylthioadenosine/adenosylhomocysteine
                     nucleosidase"
                     /protein_id="HGR0069548.1"
                     /translation="MKIGIIAAMPEELAYLVQHLDNAQEQVVFGNTYHTGTIASHEVV
                     LVESGIGKVMSAMSVAILADHFQVDALINTGSAGAVAEGIAVGDVVIADKLAYHDVDV
                     TAFGYAYGQMAQQPLYFESDKTFVAQIQKSLSQLDQNWHLGLIATGDSFVAGNDKIEA
                     IKSHFPEVLAVEMEGAAIAQAAHALNLPVLVIRAMSDNANHEANIFFDEFIIEAGRRS
                     AQVLLTFLKALD"
     gene            23266..23757
                     /gene="rocS"
                     /locus_tag="ACL29Z_001238"
     CDS             23266..23757
                     /gene="rocS"
                     /locus_tag="ACL29Z_001238"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000021242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromosome segregation protein RocS"
                     /protein_id="HGR0069549.1"
                     /translation="MSIEMTVSEIAEVLGLSRQAINNRVKELPEEDTDKNDKGVTVVT
                     RSGLIKLEEIYKKTIFEDEPVSEDVKQRELMEILVDEKNAEILRLYEQLKAKDRQLSE
                     KDEQMRIKDRQIAEKDKQLDQQQQLTLQAMKDQENLKLELDQAKEEVQSTKKGFFARL
                     FGG"
     gene            23855..24445
                     /locus_tag="ACL29Z_001239"
     CDS             23855..24445
                     /locus_tag="ACL29Z_001239"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399240.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3'-5' exonuclease"
                     /protein_id="HGR0069550.1"
                     /translation="MERLEDYIAFDLEFNQHEGQTHLIQVSAVRFRDGRESDAYDSYV
                     HTSVPLKSFINGLTGITAETLKDAPPVEKVLEEFQEFVGSLLMIGYNAAKSDLPILAE
                     HGLDYSQQYKVDLYDEAFERRSSDLHGIANLKLQTVASFLGFQGQSHNSLEDARMTAR
                     VYESFLESDQARELLETESSLSNNPFGGLDLSQLFD"
     gene            24454..26217
                     /locus_tag="ACL29Z_001240"
     CDS             24454..26217
                     /locus_tag="ACL29Z_001240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000801733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerophosphoryl diester phosphodiesterase
                     membrane domain-containing protein"
                     /protein_id="HGR0069551.1"
                     /translation="MKPEKPKKLGLKQIYLNLDKILFLFFLIFMIVEYLWVPFNSWLA
                     SFLLDQTGYLFISYNNVLAILTHSPLISLAFLALIVINLLVAYFQIGLLFIGARHLLY
                     NEKRRLIEYIRKVFHESFGFMKKLTCAKALFIFFYIAMLFPFIRKMLKIYYLNKIVIP
                     EFIQAYLEDRYWMWWLSILLLSLIFLYVSVRLMFALPKIVYDQLTVREAVMFSLEKTK
                     KRVTFYAWNLFYILLKAHLLFYLPLIPLLLAQTLVDDITQRESLILGILNFVVIKNLY
                     YMALTYFLVKFVSFLTGKELDMLPRREKDHIVRWGVMTCASLFFALEGYIYLEAPMVH
                     LPQLISHRGVSNANGIQNTVESLETTAQLKPDLVETDVQETKDGQFVMMHDANLKNLA
                     GINKSPQDLNLEELKGIDIFENGYQTKISSFEDYLSRANELGQKLLIEIKTSKKDSPD
                     MMNRFLARYAAMLKIYGHQIQSLDYHVVEKVRQYDAELPVYFIMPYNSVFPKTRATGY
                     TMEYSTLDEYFVSKLWTTDQKLYVWTVNDSEAISKSLHLGVDGVITDDLEKVQREIEV
                     AQEDPEYTDLLLKKALEFFEF"
BASE COUNT         8035 a         4804 c         5797 g         7798 t
ORIGIN      
        1 ctcaagtctg atggcaaaat ggctgaaaaa gaatgggtct acgattctca tagtcaagcc
       61 tggtactact tcaaatctgg tggctacatg gcgaaaaatg agacagtaga tggttatcag
      121 cttggaagcg atggtaaatg gcttggagga aaagctacaa ataaaaatgc tgcttactat
      181 caagtagtgc ctgtcacagc caatgtttat gattcagatg gtgaaaagct ttcctatata
      241 tcgcaaggta gtgtcgtatg gctagataag gatagaaaaa gtgatgacaa gcgcttggct
      301 attactattt ctggtttgtc aggctatatg aaaacagaag atttacaagc gctagatgct
      361 agtaaggact ttatccctta ttatgagagt gatggccacc gtttttatca ctatgtggct
      421 cagaatgcta gtatcccagt agcttctcat ctttctgata tggaagtagg caagaaatat
      481 tattcggcag atggcctgca ttttgatggt tttaagcttg agaatccctt ccttttcaaa
      541 gatttaacag aggctacaaa ctacagtgtt gaagaattgg ataaggtatt tagtttgcta
      601 aacattaaca atagcctttt ggagaacaag ggcgctactt ttaaggaagc cgaagaacat
      661 taccatatca atgcccttta tctccttgcc catagtgccc tagaaagtaa ctggggaaga
      721 agtaaaattg ccaaagataa gaataatttc tttggcatta cagcctatga tacgacccct
      781 tacctttctg ccaagacatt tgatgatgtg gataagggaa ttttaggtgc aaccaagtgg
      841 attaaggaaa attatatcga taggggaaga actttccttg gaaacaaggc ttctggtatg
      901 aatgtggaat atgcttcaga cccttattgg ggcgaaaaaa ttgctagtgt gatgatgaaa
      961 atcaatgaga agctaggtgg caaagattag tactataagt gaatatgatt tgagtgaata
     1021 gtaagttaaa aatcctgatt tcaagtaaaa tcaggatttt ttcatggatg caattttttt
     1081 ggagtctggt gtgacgcgga gggtcttttg tcctgtgtaa gtgacaaagc cgggttttcc
     1141 accagttggt ttattgagtt ttttgacttc aatcatatct acctgcacca gattcgacag
     1201 gcgcccttga gagaagtagg cagctaactc tgctgcgtct gtcttgactg catcagatgg
     1261 gtcaagattt cctgagatga caacatggct tccaggaatg tccttagcat ggaaccaaag
     1321 ttcctccttg cgggccattt taaaggtcaa ttcctcattt tgaagattgt ttcgtccgac
     1381 atagatgatg gttttgccat cgcttgctag atattgttct agttttttgc gtttctggat
     1441 tttctcccgt tgtcttctgc ggataaaacc tgtttgaatc aattcttcac ggatttcagc
     1501 gatttcttcc agtccagctt ggttgaggac ggtttctaca ctttccagat agagaatagt
     1561 ggctttggtt tcttcaatca aatcagtcaa gtatttgaca gcttctttga gtttctgata
     1621 ccgtttaaaa tagcgttggg cattctggtt gggagtcaga gccttatcaa gcgcaatcat
     1681 gataggttgg ttggtatagt agttgtctag gataacctgg tcttggtcgt taggcacttg
     1741 gtgtaggaag gttgtcagca attctccttt ttgacgaaat tcttcagcgt tgtctgtcgc
     1801 cagtaactct ttttcctgtt ttttgagttt gtgtcggttt ttctgaagtt cattttcaac
     1861 acgacgaatc agttcactgg cctgctgttt gacgcggtcg cgctcagcct tatccttata
     1921 gtaggtgtcc aacaaatcag aaagatttgc aaaaggctct cccacctgat ttgcaaaagg
     1981 aactggactg aaggaagtct tagtcaagca tggcttggtt tcttgattga aaaaatttcg
     2041 gaaagcggaa agtttttcac taaccagtat cctttccaat tcatttgccg tatcgcgtcc
     2101 cagaccttga aagaggcttt gaagattttt tgctgttagt tcttgggttt gcaggatttc
     2161 aaagagcttt tcatccttga tagtaaaagg attgagagat tctgtacttg gcggagcgat
     2221 ataggtcgat cctggaagta aggtgcggta gctattttgt gaaaaaccga cgtgtttgat
     2281 aacttcgatg attttatgac tgcttttatc gaccagtaga atattactgt gtttccccat
     2341 aatttcaata atcaaggtag cctggatatg gtctccaatc tcgtttttat tggaaactgt
     2401 aatttccaca atacggtcat tttccacttg ctcaatcgac tcaatcaggg ccccctgcaa
     2461 atactttctc aaaaccatga taaaggtaga aggttgagct ggattttcaa aagtcgtttg
     2521 ggtcagctga atgcgtccaa aaactggatg ggcagaaagg agcaggcgat ggctttggcg
     2581 attgctgcgg atttgcaaga ccaactcttg ttcaaaaggc tgattgattt tctggatgcg
     2641 accattcact aattcgcttc gcaattcctc aactatgtgg tgtaaaaaaa atccatcaaa
     2701 tgacatcgtt ctctccttgt gattgtattc catagtatta tatcaaaaag gtagaataaa
     2761 atcatagaaa tgtggtataa taaagccaag taaagagaaa cgagaagcac atgtatattg
     2821 aaatggtaga tgaaactggt caagtttcaa aagaaatgtt gcaacaaacc caagaaattt
     2881 tggaatttgc agcccaaaaa ttaggaaaag aagacaagga gatggcagtc acttttgtga
     2941 ccaatgagcg tagtcatgaa cttaatctgg agtaccgtga caccgaccgt ccgacagatg
     3001 tcatcagcct tgagtataaa ccagaattgg aaattgcctt tgacgaagag gatttgcttg
     3061 aaaatccaga attggcagag atgatgtctg agtttgatgc ctatattggg gaattgttca
     3121 tctctatcga taaggctcat gagcaggctg aagaatatgg tcacagcttt gagcgtgaga
     3181 tgggcttctt ggcagtacac ggctttttac atattaacgg ctatgatcac tacactccgg
     3241 aagaagaagc ggagatgttc ggtttacaag aagaaatttt gacagcctat ggactcacaa
     3301 gacaataaac gaaaatggaa aaatcgtgac ttgatatcca gtttagaatt tgctttgaca
     3361 ggtattttta ctgctatcaa ggaagaacgc aatatgcgaa aacacgcagt gacggctcta
     3421 gtggtcatcc ttgcaggttt tgtttttcag gtgtcacgaa tcgaatggct ctttctccta
     3481 ttgaatattt tcttggtagt agcctttgag attatcaact ctgctattga aaatgtggtg
     3541 gatttggcca gtcactatca cttttccatg ctggctaaaa atgccaagga tatggcggcc
     3601 ggcgcggtat tagtggtttc tcttttcgca gccttaacag gcgcattgat ttttctccca
     3661 cgaatctggg atttattatt ttaaacagta agaggaaatt atgactttta aatcaggctt
     3721 tgtagccatt ttaggacgtc ccaatgttgg gaagtcaacc tttttaaatc acgttatggg
     3781 gcaaaagatt gccatcatga gtgacaaggc gcagacaacg cgcaataaaa tcatgggaat
     3841 ttacacgact gataaggagc aaattgtctt tatcgacaca ccagggattc acaagcctaa
     3901 aacagctctc ggagatttca tggttgagtc tgcctacagt acccttcgcg aagtggacac
     3961 cgttcttttc atggtgcctg ctgatgaagc gcgtggtaag ggggacgata tgattatcga
     4021 gcgtctcaag gctgccaagg ttcctgtgat tttggtggtg aataaaatcg ataaggtcca
     4081 tccagaccag ctcttgtctc agattgatga cttccgtaat caaatggact ttaaggaaat
     4141 tgttccaatc tcagcccttc agggaaataa cgtgtctcgt ctagtggata ttttgagtga
     4201 aaatctggat gaaggtttcc aatatttccc gtctgatcaa atcacagacc atccagaacg
     4261 tttcttggtt tcagaaatgg ttcgcgagaa agtcttgcac ctaactcgtg aagagattcc
     4321 gcattctgta gcagtagttg ttgactctat gaaacgagac gaagagacag acaaggttca
     4381 catccgtgca accatcatgg tcgagcgcga tagccaaaaa gggattatca tcggtaaagg
     4441 tggcgctatg cttaagaaaa tcggtagcat ggcccgtcgt gatatcgaac tcatgctagg
     4501 agacaaggtc ttcctagaaa cctgggtcaa ggtcaagaaa aactggcgcg ataaaaagct
     4561 agatttggct gactttggct ataatgaaag agaatactaa gtagaggtag gctcatgcct
     4621 gcttcttgtt tttacagaag gaggacttat gcctgaatta cctgaggttg aaaccgtttg
     4681 tcgtggctta gaaaaattga ttataggaaa gaagatttcg agtatagaaa ttcgctaccc
     4741 caagatgatt aagacggatt tggaagagtt tcaaagggaa ttgcctagtc agattatcga
     4801 gtcaatggga cgtcgtggaa aatatttgct tttttatctg acagacaagg tcttgatttc
     4861 ccatttgcgg atggagggca agtattttta ctatccagac caaggacctg aacgcaagca
     4921 tgcccatgtt ttctttcatt ttgaagatgg tggcacgctt gtttatgagg atgttcgcaa
     4981 gtttggaacc atggaactct tggtgcctga ccttttagac gcctacttta tttctaaaaa
     5041 attaggtcct gaaccaagcg aacaagactt tgatttacag gtctttcaag ctgcccttgc
     5101 caagtccaaa aagcctatca aatcccatct cctagaccag accttggtag ctggacttgg
     5161 caatatctat gtggatgagg ttctctggcg agctcaggtt catccagcta gaccttccca
     5221 gactttgaca gcagaagaag cgactgccat tcatgaccag accattgctg ttttgggcca
     5281 ggctgttgaa aaaggtggct ccaccattcg gacttatacc aatgcctttg gggaagatgg
     5341 aagcatgcag gactttcatc aggtctatga taagactggt caagaatgtg tacgctgtgg
     5401 taccatcatt gagaaaattc aactaggcgg acgtggaacc cacttttgtc caaactgtca
     5461 aaggagggac tgatgggaaa aatcatcgga atcactgggg gaattgcctc tggtaagtca
     5521 actgtgacaa attttctaag acagcaaggc tttcaagtag tggatgccga cgcagtcgtc
     5581 caccaactac agaaacctgg tggtcgtctg tttgaggctc tagtacagca cttttggcaa
     5641 gaaatcattc ttgaaaacgg agaactcaat cgccctctcc tagctagtct catcttttca
     5701 aatcctgatg aacgagaatg gtctaagcaa attcaagggg agattatccg tgaggaactg
     5761 gctactttga gagaacagtt ggctcagaca gaagagattt tcttcatgga tattccccta
     5821 ctttttgagc aggactacag cgattggttt gctgagactt ggttggtcta tgtggaccga
     5881 gatgcccaag tagaacgctt aatgaaaagg gaccagttgt ccaaagatga agctgagtct
     5941 cgtctggcag cccagtggcc tttagaaaaa aagaaagatt tggccagcca ggttcttgat
     6001 aataatggca atcagaacca gcttcttaat caagtgcata tccttcttga gggaggtagg
     6061 caagatgaca gagattaact ggaaggataa tctgcgcatt gcctggtttg gtaattttct
     6121 gacaggagcc agtatttctt tggttgtacc ttttatgccc atcttcgtgg aaaatctagg
     6181 tgtagggagt gagcaagtcg ctttttatgc aggcttagca atttctgtct ctgctatttc
     6241 cgcggcgctc ttttctccta tttggggtat tcttgctgac aaatacggcc gaaaacccat
     6301 gatgattcgg gcaggtcttg ctatgactat cactatggga ggcttggcct ttgtcccaaa
     6361 tatctattgg ttaatctttc ttcgtttact aaacggtgta tttgcaggtt ttgttcctaa
     6421 tgcaacggca ctgatagcca gtcaggttcc aaaggagaaa tcaggctctg ccttaggtac
     6481 tttgtctaca ggcgtagttg caggtactct aactggtccc tttattggtg gctttatcgc
     6541 agaattattt ggcattcgta cagttttctt actggttggt agttttctat ttttagctgc
     6601 tattttgact atttgcttta tcaaggaaga ttttcaacca gtagccaagg aaaaggctat
     6661 tccaacaaag gaattattta cctcggttaa atatccctat cttttgctca atctcttttt
     6721 aaccagtttt gtcatccaat tttcagctca atcgattggc cctattttgg ctctttatgt
     6781 acgcgactta gggcagacag agaatcttct ttttgtctct ggtttgattg tgtccagtat
     6841 gggcttttcc agcatgatga gtgcaggagt catgggcaag ctaggtgaca aggtgggcaa
     6901 tcatcgtctc ttggttgtcg cccagtttta ttcagtcatc atctatctcc tctgtgccaa
     6961 tgcctctagc ccccttcaac taggactcta tcgtttcctc tttggattgg gaaccggtgc
     7021 cttgattccc ggggttaatg ccctactcag caaaatgact cccaaagccg gcatttcgag
     7081 ggtctttgcc ttcaatcagg tattctttta tctgggaggt gttgttggtc ccatggcagg
     7141 ttctgcagta gcaggtcaat ttggctacca tgctgtcttt tatgcgacga gcctttgtgt
     7201 tgcctttagt tgtctcttta acctgattca atttcgaaca ttattaaaag taaaggaaat
     7261 ctagtgcgag taaaaattaa tctcaaatgc tcctcttgtg gcagtatcaa ttacctaacc
     7321 agtaaaaatt caaaaaccca tccagacaag attgaggttt taaagtattg tcccaaggaa
     7381 agaaaagtaa ccctacatct tgaatctaag tagattttat ggtaaaataa tagggatttt
     7441 aaggagtttg atatgtataa cctattatta accattttat tagtattatc tgttgtgatt
     7501 gtgattgcaa ttttcatgca accaaccaaa aaccaatcca gcaatgtatt tgatgccagt
     7561 tcaggtgatt tgtttgaacg cagtaaagct cgcggttttg aagctgtaat gcagcgtttg
     7621 acagggattt tagtcttttt ctggctagcc attgccttag cattgacggt attatcaagt
     7681 agataagaaa ataatgggca ggactaggtc tttgcctctt tttattttta aaggatgttt
     7741 gagaaggttt tacagtaaaa gaaaattaaa aaatctagaa agaaaatatg aaagatagaa
     7801 taaaagaata tttacaagac aagggaaagg tgactgttaa tgatttggct caggctttgg
     7861 gaaaagacag ttccaaggat tttcgtgagt tgattaaaac cttgtcctta atggaaagaa
     7921 agcaccaaat tcgttttgaa gaagatggta gtctgacatt agaaattaag aaaaaacatg
     7981 agattaccct caaggggatt tttcatgccc ataaaaatgg ctttggcttt gttagtctgg
     8041 aaggcgagga ggacgacctt tttgtaggga aaaatgatgt caactatgct attgatggtg
     8101 ataccgtcga ggtagtgatt aagaaagtcg ctgaccgcaa taagggaaca gcagcagaag
     8161 ccaaaattat tgatatccta gaacacagtt tgacaacagt tgtcgggcaa atcgttctgg
     8221 atcaggaaaa gcctaagtat gctggctata ttcgttcaaa aaatcagaaa atcagtcaac
     8281 cgatttatgt taagaaacca gccctaaagt tagaaggaac agaagttctc aaggtcttta
     8341 tcgataaata cccaagcaag aaacatgatt tctttgtcgc gagtgttctc gatgtggtgg
     8401 gacactcaac ggatgtcgga attgatgttc ttgaggtttt ggaatcaatg gacattgtat
     8461 ccgagtttcc agaagctgtt gttaaggaag cagaaagtgt gcctgatgct ccgtctcaaa
     8521 aggatatgga aggtcgtctg gatctaagag atgaaattac ctttaccatt gacggtgcgg
     8581 atgccaagga cttggacgat gcagtgcata tcaaggctct gaaaaatggc aatctggagc
     8641 ttggggttca catcgcagat gtttcttatt atgtgaccga ggggtctgcc cttgacaagg
     8701 aagcccttaa ccgtgcgact tctgtttacg tgacagaccg agtggtgcca atgcttccag
     8761 aacgactatc aaatggcatc tgctctctca atccccaagt tgaccgcctg acccagtctg
     8821 ctattatgga gattgataaa catggtcgtg tggtcaacta taccattaca caaacagtta
     8881 tcaagaccag ttttcgtatg acctatagcg atgccaatga tatcctagct ggcgatgaag
     8941 aaaagagaaa aaaatatcat aaaattgtac caagtatcga actcatggcc aagcttcatg
     9001 aaactttaga aaacatgcgt gtgaaacgtg gagctctcaa ttttgatacc aatgaagcga
     9061 agattttagt ggataaacaa ggtaagcctg ttgatatcgt tcttcggcag cgtggtattg
     9121 ccgagcggat gattgagtct tttatgttga tggctaatga aacagttgcc gaacatttca
     9181 gcaagttgga tttgcctttt atctatcgaa ttcacgagga gcctaaggct gaaaaggttc
     9241 agaagtttat tgattatgct tcgagttttg gcttgcgcat ttatgggact gccagtgaga
     9301 ttagtcagga ggcacttcaa gacatcatgc gtgctgttga gggagaacct tatgcagatg
     9361 tattgtccat gatgcttctt cgctctatgc agcaggctcg ttattcggag cacaatcacg
     9421 gccactatgg actagctgct gactattata ctcactttac cagtccaatt cgtcgttatc
     9481 cagaccttct tgttcaccgt atgattcgag attacggctg ttctaaggaa atagcagagc
     9541 attttgaaca agtgattcca gagattgcga cccagtcttc caaccgtgaa cgtcgtgcca
     9601 tagaagctga gcgtgaagtc gaagccatga aaaaggctga gtatatggaa gaatacgtgg
     9661 gtgaagagta tgatgcagtt gtatcaagta ttgtcaaatt cggtctcttt gtcgaattgc
     9721 caaacacagt tgaaggcttg attcacatca ctaatctacc tgaattttat catttcaatg
     9781 agcgtgattt gactcttcgt ggagaaaaat caggtatcac tttccgagtg ggtcagcaga
     9841 tccgtatccg tgttgaaaga gcggataaaa tgactggaga gattgatttt tcattcgtac
     9901 ctagtgagtt tgatgtgatt gaaaaaggct tgaaacagtc tagtcgtagt ggcagagggc
     9961 gtggttcaaa tcgtcgttcg gataagaagg aagacaagag aaaattagga cgctcaaatg
    10021 ataagcgtaa gcattcacaa aaagacaaga agaaaaaagg aaagaaacct ttttacaagg
    10081 aagtagctaa gaaaggagcc aagcatggca aagggcgagg gaaaggtcgt cgcacaaaat
    10141 aaaaaggcac gccacgacta tacaatcgta gatacgctag aggcagggat ggtcctgact
    10201 ggaactgaaa tcaagagtgt acgagctgct cgaattaatc tcaaggatgg ctttgctcaa
    10261 gtgaaaaatg gagaagtttg gctgagcaat gttcatatcg cgccttacga agagggcaat
    10321 atctggaacc aggaaccaga acgtcgtcgt aaactcctgc tccataaaaa gcaaattcaa
    10381 aaattggaac aagagaccaa agggacagga atgaccttag ttccccttaa ggtctatata
    10441 aaagatggct acgctaagct tcttttagga cttgccaaag ggaagcatga ctatgacaaa
    10501 cgggagtcta tcaaacgtcg tgagcaaaat cgagatatcg cgcgtgtgat gaaagctgtt
    10561 aatcagcgat aaaaagagga attgaaaatg gaaaaattag ttgcctataa acgcatgcct
    10621 ttgtggaata aacaaacaat gcctgaagct gttcagcaaa agcacaatac aaaagttggg
    10681 acttggggga aaattactgt cttgaaggga gctctcaagt ttattgaatt gacagaagaa
    10741 ggggaagttc tagctgaaca cctctttgaa gcaggggcag acaatccaat ggcccaacct
    10801 caagcctggc accgagtgga agctgccaca gatgatgtgg aatggtactt ggaattttat
    10861 tgtaaacctg aggattattt tgctaaaaaa tacaatacca atcctgttca ttcagaggtc
    10921 ctagaggcca tgcagacagt gaaacaaggg aaagctttgg atttgggttg tggtcagggg
    10981 cgtaattctc tttttctagc ccagcaagat tttgatgtga cggctgtaga tcaaaatgga
    11041 ctagctcttg aaatcttgca aagcattgtg gagcaggaag atttggacat gcctgttggc
    11101 ctttacgata tcaattcagc tagcattgaa caagaatatg attttatcgt ttcaacagtt
    11161 gttctcatgt ttctacaagc ggaccgcatt ccagctatta ttcaaaatat gcaggagaaa
    11221 accagtgttg gtggttacaa ccttatcgtt tgtgccatgg acacggagga ttatccttgc
    11281 tcggttaact tcccattcac ctttaaagaa ggagaactgg cagactatta caaggattgg
    11341 gaattggtta agtacaatga aaatccaggc catttgcatc gtcgcgatga gaatggcaat
    11401 cgtattcaac tacgctttgc gaccttacta gctaagaaaa tcaagtaaac acacatgaag
    11461 attaggaatt ttcctgatct tttttctttt ttacgaatga tatagaaaag gagggaattc
    11521 atgtttgttg cgagagatgc taggggagaa ttggtaaatg tgttagagga taaacttgag
    11581 aagcaagcat acacctgccc agcttgtgga ggccagctcc atttgcgtca aggaccaagt
    11641 gtacggacgc attttgccca taaatcctta aaagactgtg attttttctt tgaaaatgaa
    11701 agtccagaac acctggccaa taaggaatcc ctctatcact ggttgaaaaa agagacaaag
    11761 gttcaattag agtacccgct ttcagaactt aaacagattg cggatgtatt tgtaaatggc
    11821 aatctagctc tagaagttca gtgtagtccc ttgcctcaga aagtccttaa agagcgaagt
    11881 gagggatatc gtagtcaggg ttaccaagta ctgtggttgc tgggtcaaaa actgtggctc
    11941 aaggagcgtt tgactcgtct acagcaaggt tttctttatt tcagtcaaaa catgggcttt
    12001 tatgtttggg aattagacaa ggaaaaacaa gttttaagac tcaaatacct gatttaccag
    12061 gatctccgcg gtaaactcca ttatcaaatc aaggaatttt cctatggtca aggtagttta
    12121 ttggaaatat tgcgtcttcc ctataagaga caaaaaatat ctcattttac agtttctgag
    12181 gacaaggaca tctgtcgcta tatccggcaa caactttatt atcaaaatct cttttggatg
    12241 aaagaacaag cagaagccta tcaaaaggga gaaaatatcc tgacttatgg actgaaagaa
    12301 tggtatccac aaattcgacc aatagtgggc aaatttttcc agattgaaca agacttgact
    12361 agctattatc agcactttta tacctattac caaaaaaatc ctcaaaatga ttggcaaaag
    12421 ctttatccac cagcctttta tcagcaatat ttcttgaaaa atatggtaga atggaaagga
    12481 tggaggaatc taatggtatt acaaagaaat gaaataaatg aaaaagatac atgggatcta
    12541 tcaacgatct acccaactga ccaggcttgg gaagaagcct taaaagattt aacagaacaa
    12601 ttggagacag tagcccagta tgaaggccat ctcttggata gtgcggataa cctactagaa
    12661 atcactgaat tttctcttga aatggaacgc cagatggaga agctttacgt ttatgctcat
    12721 atgaagaatg accaggatac acgtgaagct aagtatcaag agtactatgc caaggccatg
    12781 acactctaca gccagttaga ccaagccttt tcattctatg atcctgaatt tatggagatt
    12841 agcgaaaagc agtatgctga ctttttagaa gctcaaccaa agctgcaggt ttatcaacac
    12901 tattttgaca agctcttgaa aggcaaggat cacgttcttt cacaacgtga agaagaatta
    12961 ttggctggag ctggagaaat ctttggttca gcaagtgaaa ccttcgctat cttggacaat
    13021 gcggatattg tgttccctta tgtcctagac gatgatggta aagaagttca gctatctcat
    13081 gggacttaca cacgtttgat ggagtctaaa aaacgtgagg ttcgccgtgg tgcctatcaa
    13141 gctctttatg cgacttacga acaattccaa cacacctatg ccaaaacctt gcaaaccaat
    13201 gttaaggtgc aaaattaccg tgctaaagtt cgtaactaca agagtgctcg tcatgcagcc
    13261 ctcgcagcga attttgttcc agaaagtgtt tatgacaatt tggtagcagc agttcgcaag
    13321 catttgccac tcttacatcg ctatcttgag cttcgttcaa aaatcttggg gatttcagat
    13381 ctcaagatgt acgatgtcta cacaccgctt tcatctgttg aatacagttt tacctaccaa
    13441 gaagccttga aaaaagcaga agatgctttg gcagtcttgg gtgaggatta cttgagccgt
    13501 gttaaacgtg ccttcagcga gcgttggatt gatgtttacg aaaatcaagg caagcgttca
    13561 ggtgcctact ctggtggttc ttacgatacc aatgccttta tgcttctcaa ctggcaagac
    13621 aatctggaca atctctttac tcttgttcat gaaacaggtc acagtatgca ttcaagctat
    13681 actcgtgaaa ctcagcctta tgtttacggg gattactcta tctttttggc tgagattgcc
    13741 tcaactacca atgaaaatat cttgacggag aaattattgg aagaagtgga agacgacgca
    13801 acacgctttg ctattctcaa taacttccta gatggtttcc gtggaacagt tttccgccaa
    13861 actcaatttg ctgagtttga acacgccatt caccaagcag atcaaaatgg ggaggtcttg
    13921 acaagcgatt tcctaaataa actctacgca gacttgaacc aagagtatta tggtttgagt
    13981 aaggaagaca atcctgaaat ccaatacgag tgggctcgca ttccacactt ctactataac
    14041 tactatgtat atcaatattc aactggcttt gcggccgcct cagccttggc tgaaaaaatt
    14101 gtccatggta gtcaagaaga ccgtgaccgc tatatcgact acctcaaggc aggtaagtcg
    14161 gactatccac ttaatgtcat gagaaaagct ggtgttgata tggagaagga agactacctc
    14221 aacgatgcct ttgcagtctt tgaacgccgt ttaaatgagt ttgaagccct tgttgaaaaa
    14281 ttaggattgg cataaaatgg ttgaatcgta tagtaagaat gctaaccata acatgcgtcg
    14341 tcctgtcgtc aaagaagaaa ttgtagactt gatgcgtcag cgtcaaaagc aggtcacagg
    14401 tttcttgaaa gaattggaag actttgcccg caaggaaaat attcctatta ttccccatga
    14461 aacggttgct tatttccgtt ttcttatgga aaccatgcag cctaaaaata ttctggaaat
    14521 tgggacggct atcggttttt cagctctctt gatggctgaa catgcgccaa atgctaagat
    14581 tacaactatt gatcgtaatc cagaaatgat tggttttgcc aaggaaaatt ttgcccagtt
    14641 tgacagtcgc aagcaaatca ctctcctaga gggagatgcg gtggatgtct tatctacact
    14701 gacagagtct tatgatttcg tctttatgga ttctgccaag tctaaataca tcgtctttct
    14761 gccagaaatc ctcaaacatt tggaagttgg tggtgtggtt gtcttggatg atatttttca
    14821 aggtggtgat gttgccaagg atattatgga agtccgtcgt ggtcagcgaa ccatttatcg
    14881 aggccttcaa aaattatttg atgcaacctt agacaatcca gaactcaccg caacattagt
    14941 gcctttagga gatggtattc tcatgcttcg taaaaatgta gcagatgttc aactgtctga
    15001 aagcgaatga ttttcagaaa aatttaagaa aaaatagtaa aatagataga gtaacactta
    15061 tctcaaagga gtagacatga agaaaaaatt attggcaggt gccatcacac tattatcagt
    15121 agcaacttta gcagcttgtt cgaaagggtc agaaggggca gaccttatca gcatgaaagg
    15181 ggatgtcatc acagaacatc aattttatga gcaagtgaaa aacaaccctt cagcccaaca
    15241 agtcttgtta aatatgacca tccaaaaagt ttttgaaaaa caatatggct cagagcttga
    15301 tgataaagag gttgatgata ctattgccga agaaaaaaaa caatatggcg aaaactacca
    15361 acgtgtcttg tcacaagcag gtatgactct tgaaacacgt aaagctcaaa ttcgtacaag
    15421 taaattagtt gagttggcag ttaagaaggt agcagaagct gaattgacag atgaagccta
    15481 taagaaagcc tttgatgagt acactccaga tgtaacggct caaatcatcc gtcttaataa
    15541 tgaagataag gccaaagaag ttctcgaaaa agccaaggca gaaggtgctg attttgctca
    15601 attagccaaa gataattcaa ctgatgaaaa aacaaaagaa aatggtggag aaattacctt
    15661 tgattctgct tcaacagaag tacctgagca agtcaaaaaa gccgctttcg ctttagatgt
    15721 ggatggtgtt tctgatgtga ttacagcaac tggtacacaa gcttacagta gccaatatta
    15781 cattgtaaaa ctcactaaga aaacagaaaa atcatctaat attgatgact acaaagaaaa
    15841 attaaaaact gttatcttga ctcaaaaaca aaatgattca acatttgttc aaagcattat
    15901 cggaaaagaa ttgcaagcag ccaatatcaa ggttaaggac caagccttcc aaaatatctt
    15961 tacccaatat atcggtggtg gagattcaag ctcaagcagt agtacatcaa acgaatagtc
    16021 caaatcaatg agtcagggaa aaaaactcga cttcaggaaa aaataaagca aacattccca
    16081 caataaaacg catagtacaa ggtttgtact gcccccaaaa gttagacaat taatttatct
    16141 gaaggattta gttctgtatt gcacagggct aagtcctttt agttttacct taattctctt
    16201 attgttgtaa taatcaatat agtctataat ggcttgttcc aattgattaa gtgatttaaa
    16261 tgttttctca tagccataaa acatttcgga ttttaaaatg ccaaagaaag attccatcct
    16321 accgttgtct tggctgtttc ctttgcgtga catagatgct tgaattccct tactctctag
    16381 gaagcgatga taagaatcgt gttggtattg ccagccttgg tcactatgga gaatcgtatt
    16441 ctcgtagtgc ttctctttga atgcctgttc caacattaac gatcaatcaa tttaatcatg
    16501 tacctaatat tagaattgtt tatcccaaat ttatttgaaa gcttctctaa gctatatcct
    16561 tgttttctaa gttcatagat ctgaacttta tcatcataag ttaatttcat aataaaaaca
    16621 ccccaaaagt tagatttttt ctgtctaact tttggggtgt agttcatgta cacctgatat
    16681 gatgcgtttt ataattttaa agactttttg accagcctca tttttttaac ttgatactca
    16741 gtgaaaagca aagattaaac taggaagcta gctgtaggct gctcaaagaa cagctttgag
    16801 gttgcagata aaacttgtga ggtaaccaac atatataatg tgaagctgac gtggtttgaa
    16861 tagattttag aagggtatga gtctggaagt tttaatggat aatgcaagat tccatagaat
    16921 gggtaagcta gagttcttat gtgaagagtt tgggcataaa cttttacctt ttcctcccta
    16981 ctcatcttag tatagaaaag tgaatctaaa atagtacata actgcttcta aaacattctt
    17041 ataaattgat ttaaattctc aaatcatatt attcagttct tatttcattt tgctctacaa
    17101 tcctgttgag aagacacgtg ttcatatcaa aaaggtattg gcaagttgca ataccttttt
    17161 acaaggttct tttgtcttat ttttgtttca actgactata tctcctatgg ttctagttca
    17221 gaaggctagg ctataattat gattgataag aagtatcatt ccaagtattg agagtgaatg
    17281 tttcaaaatc atgggtttct ataatggtca ggctggcatt tgctagaccg ccatctttac
    17341 gaagaagtgg ttctttatag cctaggagag tacgaagact ggcagtaaga ttggcgccgt
    17401 gtccgacaat tagaatacgc tcagctggac tatcttttaa tgatttgata aattggatgg
    17461 tccgttgagt tgtactatag agggattcgg ctccgaacat tcgagtgtca aattgagcaa
    17521 gatttgaacg aaaagcctgg atttgttgcg ggtaaatagc ttccaaggtt gcaattttca
    17581 aaccttctaa cttcccaagt tgccattcac ggagattagg aacgatttct aaagaacagg
    17641 gggtatggag ttgaatttgg ataatctcag cagatttgac cgctcgaggt aaatcacttg
    17701 aataaatctg atcaaaagga atttccttga gatactgacc aagtcgtttt agggtttcaa
    17761 tggattcagg aagaagagga gaatcaccgc tagcaccttg aaaacgacct tcttggttcc
    17821 agagggtacg accgtggcgg acaaagtaga gtttcattac ttgatgtcct ccaaaatatc
    17881 tacaaagtct gcctttacaa agctagccaa gtcttgtggc gcgacgataa tgctgtgtcc
    17941 gacttcgcct gcagagacaa tcatttgatc caaacctaga gcaattttat cgataaaaat
    18001 gggataattg tgtttctgac gaattccgac aggattattg gctccatgaa tgtaaccagt
    18061 tgttttttct aagtcctttt gtggaatcat gctcactttt ttattgccag aaattttagc
    18121 tagtttcttt tcagacaagt gctgagtgat agggacaatt ccgataatcg gtccggtctt
    18181 gtctcccaaa agcgccaagg ttttgaaaat ctgatctcgt tcataacctt gaggaagctc
    18241 tccttctagg gcattgattt gaatcccctg atgagggata gctgctttag ataggatttg
    18301 ttctaccaat gtttttttga ttttaacttt ttttgccatt atttatattt atcctccaat
    18361 tgactcatcc aaataccaag ccagattccc agcgcaaaga agaaggcgat gatgacataa
    18421 ccgacaagtg aaagtcctgt gtattggata ctttcagcgt ttcctgcatt tggaattaag
    18481 atcaaaaggg tacttgatag gacgataccg atgatgaaat gatagacgcg tgagtggtag
    18541 ttgtttaagg cataatccat caattttgaa aaaacgatga gagttgcacc tgcaccaatt
    18601 ccaatcggaa agaaggttcc caagagatca aaagttttaa aaccagtcaa cataggagca
    18661 tagagtccca aaatcaaaag taaattcgat gggctgaggc caggaaccaa gacgccaagg
    18721 gccaatagtg cgcctgctag gacgaagtta agaaagctgg cgcttaaggt tccaacgaca
    18781 aaatttaagg catagagtcc taatccagaa atgataaagg ttgtccataa ccaagctaaa
    18841 tcaatcttgt ctcggtcaga ttctcgagtt gattctttga ggaggctagg aactgtaccg
    18901 ataatagctc ccgcaaagct ccataataca aagacctgat aattttcaag caggtattca
    18961 atcgggtagg aaaataagcc gattcccaga agcataccga tggcaactgg aataaagtac
    19021 aaaacatttt ctttaaggtc tttaaaggga tgggccagaa agccaatcat tcgttcatag
    19081 attcctaaga ttgctgctag aacccctccg gaaattcctg gtaggataaa tccaagagca
    19141 attacaatcc ctttaataac gcgtgctaac catgagagca tatatttcct ccaactattt
    19201 ctatttcaaa aaatccttac tatattgtat cacaatcaga cacaaaaaga aaaagcaaat
    19261 gataaacaaa tgcttttaag gttttaaaaa aagttttcga aaggtttctt ctttattttt
    19321 taagggagag ataacgttga tatctaaatc gtggtcaaag ccggcaattt ttcctttaga
    19381 tgtgtattgg tgaatatcat aatctaaatc agttttagga ctgctctcca aaaatcctga
    19441 gtctgagccg taggacggaa tccaaacaga ggtaaacttg cctgtatcaa tactgtgttc
    19501 ttccatgaag tagacaccaa cgtagatgcc gatgttttta gcacctagtg atgctagttt
    19561 tgctcgaaag ttttcgacac cttcgttcat attagacatg gttttgtctt ccacgtcaag
    19621 ccaatagtaa ctagggctgt aaggagaggc agcattgtag aaaacttcgg cagccttttc
    19681 catttcttgg gcactttttc cagctacata agcgtagaca gcaactggga cattccgctt
    19741 ttgaagttca gtgatatgac tcttataggc cttgtctatt ccattgataa atgaagcatc
    19801 attttctttt gtcgtttgag caccactgtg aacacgaaca atagcacctg aaatattttg
    19861 tgagagggca tcgtagttga tttcctcagg acgctgccag ccagagaggt caataatcgg
    19921 tttgtctaag tgtttcaaag cctgtgcttc aatctgtgct atattggatt ttgttttaaa
    19981 cgattggctg tcattaagtg ggcgattgat gattaaaatg aacatcataa tccccaaaaa
    20041 actaaataaa ataagtggat gaatttgttt tctcatatct tataattcta ccctaaaaat
    20101 caaaaaaaat caaaaaaatg ggttaaggaa gagactttag agcatttttt cattcaagag
    20161 tgcggaatga tttgaaatat ggtataataa aagggaattt ctacagaaaa gagaagatta
    20221 tgtcaaattt tgccattatt ttagcagcgg gtaaagggac tcgcatgaaa tctgatttgc
    20281 caaaagtttt gcacaaggtt gcgggtattt ctatgttgga acatgttttc cgtagtgtgg
    20341 gagctatcca acctgaaaag acagtaacag ttgtaggaca caaggcagaa ttggttgagg
    20401 aggtcttggc tggacagaca gaatttgtga ctcaatctga acagttggga actggtcatg
    20461 cagttatgat gacagagcct atcttagaag gtttgtcagg acacaccttg gtcattgcag
    20521 gagatactcc tttaatcact ggtgaaagct tgaaaaactt gattgatttc catatcaatc
    20581 ataaaaatgt ggccactatc ttgactgctg aaacggataa tccttttggc tatggacgaa
    20641 ttgttcgtaa tgacaatgct gaggttcttc gtattgttga gcagaaggat gctacagatt
    20701 ttgaaaagca aatcaaggaa atcaacactg gaacatacgt ctttgacaac gagcgtttgt
    20761 ttgaggcttt gaaaaatatc aataccaata acgctcaagg cgaatactat attacagacg
    20821 tcattggtat tttccgtgaa actggtgaaa aagttggcgc ttatactttg aaagattttg
    20881 atgaaagtct tggggtaaat gaccgtgtgg cgcttgcgac agctgagtca gttatgcgtc
    20941 gtcgcatcaa tcataaacac atggtcaacg gtgttagctt tgtcaatcca gaagcaactt
    21001 atatcgatat tgatgttgag attgctccgg aagttcaaat cgaagccaat gttaccttga
    21061 aagggcaaac gaaaattggt gctgagactg ttttgacaaa cggtacttat gtagtggaca
    21121 gcactatcgg agcaggagcg gtcattacca attctatgat tgaggaaagt agtgttgcag
    21181 acggtgtgac agtcggtcct tatgctcaca ttcgtccaaa ttcaagtctg ggtgcccaag
    21241 ttcatattgg taactttgtt gaggtgaaag gatcttcaat cggtgagaat accaaggctg
    21301 gtcatttgac ttatatcgga aactgtgaag tgggaagcaa cgttaatttc ggtgctggaa
    21361 ctattacagt caattatgac ggcaaaaaca aatacaagac agtcattgga gacaatgtct
    21421 ttgttggttc aaattcaacc attattgcac cagtagaact tggtgacaat tccctcgttg
    21481 gtgctggttc aactattact aaagacgtgc cagcagatgc tattgctatt ggtcgcggtc
    21541 gtcagatcaa taaagacgaa tatgcaacac gtcttcctca tcatcctaag aaccagtagg
    21601 agcctatcat ggagtttgaa gaaaaaacgc ttagccgaaa agaaatctat caaggaccaa
    21661 tatttaaact ggtccaagat caggttgaat taccagaagg caagggaact gcccaacggg
    21721 atttgatttt ccacaatggg gctgtctgtg ttttagcagt aacggatgaa caaaaactta
    21781 tcttggtcaa gcagtaccgc aaagctatcg aggctgtctc ttacgaaatt ccagccggaa
    21841 aattggaagt aggagaaaac acagcccctg tggcagctgc ccttcgtgaa ttagaggaag
    21901 aaacagccta tacagggaaa ttagaactct tgtacgattt ttattcagct attggctttt
    21961 gtaatgagaa gttaaaacta tatttagcaa gcgatttgac aaaagtggaa aatccgcgtc
    22021 cgcaggatga ggatgaaacc ttggaagtcc ttgaagtgag cttagaagaa gcgaaagaat
    22081 taatccaatc aggtcatatt tgtgatgcca agacaattat ggctgttcag tattgggagt
    22141 tgaagaaaaa atagaggagg tcagtatggg taaatcttta ttaacggatg aaatgattga
    22201 aagagctaat agaggcgaaa aaatttcagg tcctcctttg ctagatgata atgaggagac
    22261 taagatttta ccaacctctt cttcccgttt tggttatgcc aatcctaaga atcatggttt
    22321 tagccaggaa accttgaaga ttcaggtcga accatctatt cataaaagcc gtcgcattga
    22381 aaataccaag agaaatgtct tcaattctaa gttgaataaa atcttattcg cggtcatctt
    22441 tctcttgatt ttgcttgttt tagcaatgaa acttttgtaa tagaaaagga attgaaatga
    22501 aaataggaat tattgctgct atgccagaag aactggctta tctggtccag catttagata
    22561 atgcccagga gcaagttgtt tttgggaata cctatcatac aggaaccatt gcttctcatg
    22621 aagtcgttct tgtagaaagt ggaattggta aggtcatgtc tgctatgagt gtggcgattt
    22681 tggctgatca tttccaggtg gatgccctta ttaatacggg ttcagctggg gcagtagcag
    22741 aaggtatcgc tgttggggat gtcgtgattg ctgacaaatt agcctatcat gacgtggatg
    22801 tcacagcttt tggctatgct tatggacaaa tggcgcaaca accgctttat ttcgaatcag
    22861 acaaaacctt tgttgctcaa atccaaaaga gtttatctca attggaccaa aactggcatc
    22921 ttggtttgat tgctacagga gatagttttg ttgcaggaaa tgacaagata gaagcgatta
    22981 agtcccattt cccagaagtt ttagccgtgg agatggaggg ggcagctatt gctcaagcag
    23041 cgcatgccct caatctccca gtcttagtca tccgagctat gagtgacaat gccaaccatg
    23101 aagcaaacat cttttttgat gagtttatta tcgaagctgg acgtcgctct gcccaagtct
    23161 tgttgacctt tttgaaggct ttagattaag cggaaatttg acagtttttc tagcttatga
    23221 taagatttaa gtaaagaaaa gctagaaaac gtttcagagg atattatgag tattgaaatg
    23281 accgtcagtg agattgcaga ggtcttagga ttatctcgcc aagcaatcaa taaccgtgtc
    23341 aaagaattac cagaagaaga cacagataaa aatgacaaag gggtaacagt tgttaccaga
    23401 agtggcttga ttaagctaga agaaatctat aaaaaaacga tttttgaaga tgaacctgtc
    23461 agtgaagatg tcaaacaacg tgaactgatg gagattctag tggatgagaa gaatgcagaa
    23521 attcttcgtc tttatgaaca attaaaagcc aaggatcgtc agttatcaga aaaagacgag
    23581 cagatgcgta tcaaagaccg tcagattgct gagaaagaca aacaattaga tcagcaacaa
    23641 caattgaccc ttcaagccat gaaggatcaa gaaaatctta agctagagct ggaccaagca
    23701 aaagaagaag tccaatccac taaaaaaggc ttttttgctc gtttatttgg aggataatca
    23761 aggagctgtt taggttaaat gctaacctga tggcttcttt tgtttgtgaa tagtatagtt
    23821 gattagaaca gagacagtag aggagaggta cagaatggaa cgattagaag attacattgc
    23881 ttttgattta gaatttaatc agcacgaagg acaaacacac ttgattcaag tatcggcagt
    23941 gcgttttaga gatggtcggg aaagcgatgc ctatgattcc tatgttcata ccagtgtccc
    24001 tctaaaaagc tttatcaatg gtttgaccgg gattacagct gagaccttaa aagacgctcc
    24061 tccagttgag aaagtcttag aagaattcca agagtttgtg ggttctttgc tgatgatagg
    24121 ctacaatgct gctaaaagtg atttacctat tttagcagag catggtttag actatagcca
    24181 acagtacaag gtggatttgt atgatgaagc ttttgaacgt cggagttcag atttacatgg
    24241 tattgccaat ctcaaattgc aaactgttgc ctcatttctt ggatttcaag gtcagtctca
    24301 taatagttta gaggatgctc ggatgacggc gcgtgtttac gaatccttct tagagtcgga
    24361 tcaagctagg gaattgttag agacagaaag tagcttatca aacaatcctt ttggtggctt
    24421 ggacttgtct caattatttg actaggagtg cctatgaaac ctgaaaaacc taaaaaattg
    24481 ggtcttaaac agatttacct caatcttgat aaaatcctct ttctattttt cttgattttt
    24541 atgatagtgg agtatttgtg ggtaccattc aattcatggt tggctagctt cttattagat
    24601 cagacaggtt atctttttat ttcctataac aatgtcttag ccatccttac tcattctcca
    24661 ttgattagtc tagctttttt agccttgatt gtaattaacc ttctggttgc ttattttcaa
    24721 ataggactcc tctttattgg tgctcgtcat ctcctctata atgaaaagcg aaggctaatt
    24781 gagtatatcc gcaaggtttt ccatgaaagt tttggattta tgaaaaagct aacttgcgct
    24841 aaagccttgt ttatcttttt ctatatagct atgctgtttc cttttatacg gaaaatgctg
    24901 aagatttatt atcttaataa aatcgtcatt ccagagttta tccaagctta tttagaagat
    24961 agatattgga tgtggtggct gagcatccta cttctatctc ttatctttct ctatgtctct
    25021 gtcagattga tgtttgccct tccgaagatt gtatatgatc agctgactgt tcgagaagca
    25081 gtgatgttta gcttggagaa aaccaagaag agagttactt tttatgcttg gaatttattt
    25141 tacatcttgc tcaaagcaca tttattattt tatcttcctt tgattccttt attattggct
    25201 caaactttgg tagatgatat cactcagaga gagtctctga ttcttggtat tttgaatttt
    25261 gtcgtgatta aaaatctcta ttatatggct ctgacttatt ttttggttaa atttgtttca
    25321 tttttgacag gaaaggagct ggatatgctt cctaggagag aaaaagatca catcgtgcga
    25381 tggggtgtca tgacttgtgc cagtcttttc tttgccttag aaggttatat ttatctggag
    25441 gctcccatgg ttcatctacc tcaacttatt tctcaccgag gggtttccaa tgcaaatggg
    25501 attcaaaata cagtagagtc cttggaaact acagcacaac tcaaaccaga cttggtggag
    25561 acggacgtgc aggaaacaaa agatgggcag tttgtcatga tgcatgatgc taacttgaaa
    25621 aatctagcag gtatcaataa aagtcctcaa gacttaaact tggaggagct taaagggatt
    25681 gatatttttg aaaatggcta ccagactaaa atttcaagct ttgaagatta tctcagtcga
    25741 gccaacgaac ttggtcaaaa attactaatt gaaattaaaa ccagtaaaaa agatagtcca
    25801 gacatgatga accgcttttt agcccgttat gctgcaatgc tcaagattta tggacatcaa
    25861 atccagtctt tagactacca tgttgtcgaa aaagtaagac agtatgatgc cgaactgcca
    25921 gtttatttca tcatgcccta caattctgtc tttcctaaaa caagagcgac aggatatact
    25981 atggagtact caaccttgga tgaatatttt gtaagcaaac tatggacaac ggatcagaaa
    26041 ctttatgtct ggactgtcaa tgattcagaa gctatcagca aatctcttca cttaggagta
    26101 gatggagtga ttacagatga tttggaaaaa gttcagcggg aaatagaagt agcccaagaa
    26161 gatccagaat atacggattt gctcttgaaa aaagcattgg aattctttga attttagtaa
    26221 taaaaaagag gaacggttgt tcctcccatg ataggtaagt attcttgtga atgcttgctt
    26281 ttttgtggtt gcaatccgtt tacgagaatt gtttatattg ttcttgtttc aatttacttt
    26341 atagtgcttt gaagttggaa tgctacacta taacttataa aatatagtaa aatgaaccaa
    26401 aaatagtaca caatgtggta taatcttctt atgg
//
LOCUS       DBEJAU010000028        26339 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC323 isolate 683620
            SAMN38261939-rid24807223.denovo.028, whole genome shotgun sequence.
ACCESSION   DBEJAU010000028 DBEJAU010000000
VERSION     DBEJAU010000028.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261939
            Sequence Read Archive: SRR26833919
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 26339)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 26339)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576303.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576303.1
            Genome Coverage       :: 154x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/19/2025 01:05:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,121
            CDSs (total)                      :: 2,078
            Genes (coding)                    :: 1,943
            CDSs (with protein)               :: 1,943
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 36
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 72 of 135
            Pseudo Genes (incomplete)         :: 63 of 135
            Pseudo Genes (internal stop)      :: 51 of 135
            Pseudo Genes (multiple problems)  :: 46 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..26339
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261939-rid24807223.denovo.028"
                     /strain="GPSC323"
                     /isolate="683620"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            <1..379
                     /locus_tag="ACL29Z_001241"
     CDS             <1..379
                     /locus_tag="ACL29Z_001241"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000700388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="histidine motif-containing protein"
                     /protein_id="HGR0069552.1"
                     /translation="RNKNGQADTNQTEKPQTEKPEEETPREEKPQSEKPESPKPTEEP
                     EEESPEESPEESEEPQVETEKVKEKLREAEDLLGKIQDPIIKSNAKETLTGLKNNLLF
                     GTQDNNTIMAEAEKLLALLKENK"
     gene            798..1178
                     /gene="dhaM"
                     /locus_tag="ACL29Z_001242"
     CDS             798..1178
                     /gene="dhaM"
                     /locus_tag="ACL29Z_001242"
                     /EC_number="2.7.1.121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000443785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0047324 - phosphoenolpyruvate-glycerone
                     phosphotransferase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroxyacetone kinase phosphoryl donor subunit
                     DhaM"
                     /protein_id="HGR0069553.1"
                     /translation="MESIGIGLVIVSHSKHIAEGVVELISKVAKDVPITYVRGTEGGG
                     IGTSFEQVDRVVSENPADTLLAFFDLGSAKMNLKMVTDFSDKSIIINRVPIVEGAYNA
                     AALLQAGAELSVIQTQLAELEINK"
     gene            1636..2349
                     /locus_tag="ACL29Z_001243"
     CDS             1636..2349
                     /locus_tag="ACL29Z_001243"
                     /EC_number="3.1.3.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000499426.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008253 - 5'-nucleotidase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YjjG family noncanonical pyrimidine
                     nucleotidase"
                     /protein_id="HGR0069554.1"
                     /translation="MFYKFLLFDLDHTLLDFDAAEDVALTQLLKEEGVADIQAYKDYY
                     VPMNKALWKDLELKKISKQELVNTRFSRLFAHFGQEKDGSFLAQRYQFYLAQQGQTLS
                     GAHDLLDSLIERDYNLYAATNGITAIQTGRLAQSGLAPYFNQVFISEQLQTQKPDALF
                     YEKIGQQIAGFSKEKTLMIGDSLTADIQGGNNAGIDTIWYNPHHLENHTQAQPTYEVY
                     SYQDLLDCLDKNILEKITF"
     gene            2407..3009
                     /locus_tag="ACL29Z_001244"
     CDS             2407..3009
                     /locus_tag="ACL29Z_001244"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001810555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0069555.1"
                     /translation="MSEVDFNEAVNYEFTSDTCQLANSIYQSLFKFFDKKNFSGDLIF
                     TWKSPSLVKEGDYIGRRDSQVDNLRVIGNIFPNYLTNRKYSLNMNRNGCIGDFPHDFF
                     DTYLDHVAKYAYEQKVNNIKEYYPLKRAILHQENALYFRLFSNFDDFLEKNYLKTIWQ
                     VSKETPFSEMDFNMFKNISEKIIFERGSKMLNDLKSNYKK"
     gene            3147..3800
                     /locus_tag="ACL29Z_001245"
     CDS             3147..3800
                     /locus_tag="ACL29Z_001245"
                     /EC_number="3.2.2.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001841111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004844 - uracil DNA N-glycosylase
                     activity [Evidence IEA];
                     GO_process: GO:0006284 - base-excision repair [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="uracil-DNA glycosylase"
                     /protein_id="HGR0069556.1"
                     /translation="MEHSSWHALIKAQLPEGYFGKINQFMEQVYSQGTIYPPKEKVFQ
                     ALLTTLLEEVKVVILGQDPYHGPGQAQGLSFSVPDSIPAPPSLQNILKELSDDIGVKK
                     SHDLTAWAEQGVLLLNACLTVPAGQANGHAGQIWEPFTDAVIQVVNHLDRPVVFVLWG
                     AYARKKKALVTNPHHLIIESAHPSPLSVYRGFWGSKPFSKANAFLKETGQEPIDWLR"
     gene            3810..4274
                     /locus_tag="ACL29Z_001246"
     CDS             3810..4274
                     /locus_tag="ACL29Z_001246"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003012002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX domain-containing protein"
                     /protein_id="HGR0069557.1"
                     /translation="MPQLATICYIDNGKELLMLHRNKKPNDVHEGKWIGVGGKLERGE
                     TPQECAVREILEETGLKAKPVLKGVITFPEFTPDLDWYTYVFKVTEFEGDLIDCNEGM
                     LEWVPYDEVLSKPTWEGDHTFVEWLLEDKPFFSAKFVYDGDKLLDTQVDFYE"
     gene            4287..5555
                     /locus_tag="ACL29Z_001247"
     CDS             4287..5555
                     /locus_tag="ACL29Z_001247"
                     /EC_number="3.5.2.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000924471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004151 - dihydroorotase activity
                     [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0006221 - pyrimidine nucleotide
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotase"
                     /protein_id="HGR0069558.1"
                     /translation="MLLIKNGRVMDPKSGLDQVCDVLVQDGKIIKIAPEITEEGAETI
                     DATGHVVAPGLVDIHVHFREPGQTHKEDIHTGALAAAAGGFTTVVMMANTSPTISDVE
                     TLQAVLQSAAKEKINVKTVATITKNFNGKNLTDFKALLEAGAVGFSDDGIPLESSKIV
                     KEAMEEAKKLNTFISLHEEDPGLNGVLGFNENIAREHFHICGATGVAEYAMMARDVMI
                     AYATKAHVHIQHLSKEESVKVVEFAQGLGAEVTAEVAPQHFSKTEALLLTQGSNAKMN
                     PPLRLESDRRAVIEGLKSGVITVIATDHAPHHVDEKNVEDITKAPSGMTGLETSLSLG
                     LTYLVEAGELSLMELLEKMTYNPAKLYNFKAGYLAENGPADITIFDAKADRLVDSHFA
                     SKAANSPFIGETLKGQVKYTICKGQIVYQA"
     gene            5569..5829
                     /locus_tag="ACL29Z_001248"
     CDS             5569..5829
                     /locus_tag="ACL29Z_001248"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0069559.1"
                     /translation="MNYFRKRRERQAKSNSGIYCPAANRSKIQYETKEKADHAVQYDN
                     GGLVRSYYCRTCACWHTTSKSNKPPLSLKNYGLKLFGLDKSE"
     gene            5840..7201
                     /gene="pdrM"
                     /locus_tag="ACL29Z_001249"
     CDS             5840..7201
                     /gene="pdrM"
                     /locus_tag="ACL29Z_001249"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000278543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium-coupled multidrug efflux MATE transporter
                     PdrM"
                     /protein_id="HGR0069560.1"
                     /translation="MYKTKCLREKLVLFLKIFFPILIYQFANYSASFVDTAMTGQYNT
                     MDLAGVSMATSIWNPFFTFLTGIVSALVPIIGHHLGRGKKEEVASDFYQFIYLALGLS
                     VVLLGMVLFLAPTILNHIGLEAAVAAVAVRYLWFLSIGIIPLLLFSVIRSLLDSLGLT
                     KLSMYLMLLLLPLNSGFNYLLIYGAFGVPELGGAGAGLGTSLAYWVLLGISVLVLFKQ
                     EKLKALHLEKRIPLNMDNIKEGVRLGLPIGGTVFAEVAIFSVVGLIMAKFSSLIIASH
                     QSAMNFSSLMYAFPMSISSAMAIVVSYEVGAKRFDDAKTYIGLGRWTALIFAAFTLTF
                     LYIFRGNVASLYGNDPKFIDLTVRFLTYSLFFQLADTFAAPLQGILRGYKDTVIPFYL
                     GLLGYWGVAIPVATLFDSLTDFGAYSYWIGLIISLIVSGALYRWRLTVIMKRFESLAK
                     SKC"
     gene            7355..8323
                     /locus_tag="ACL29Z_001250"
     CDS             7355..8323
                     /locus_tag="ACL29Z_001250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844850.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine pyrophosphate-dependent dehydrogenase
                     E1 component subunit alpha"
                     /protein_id="HGR0069561.1"
                     /translation="MSTLDKNLLLEMFRKMEEIRRMDLKIAQLVKKGKVPGMTHFSVG
                     EEAANVGAMLALNPDDLITSNHRGHGQAIAKGIDLNGMMAEILGKYTGTCKGKGGSMH
                     IADLDAGNLGANGIVGGGMGIAVGAALSQQMQNTGKIVVCFFGDGATNEGVFHEAVNM
                     ASIWNLPVIFYCINNGYGISADIKKMTNIEHIHQRSAAYGIPGMFIEDGNNVIDVYEG
                     FQKAVDHVRSGNGPVLIESVTYRWLGHSSSDPGKYRTREEVELWKQKDPIENLRNYLI
                     ENNIASAEELEEIQAQVKEAVEASVKFAEESPFPPLESAFEDIYAD"
     gene            8339..9331
                     /locus_tag="ACL29Z_001251"
     CDS             8339..9331
                     /locus_tag="ACL29Z_001251"
                     /EC_number="1.2.4.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000448722.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-ketoacid dehydrogenase subunit beta"
                     /protein_id="HGR0069562.1"
                     /translation="METKTMSFRDTIILAMSEEMRRDENVFLMGEDVGVFGGDFGTSV
                     GMLEEFGPERVRDCPISEAAISGAAAGAAMTGLRPIVDMTFMDFSVIAMDNIVNQAAK
                     TRYMFGGKGQVPMTVRCAAGNGVGSAAQHSQSLESWFTHIPGLKVVAPGTPADMKGLL
                     KSSIRDNNPVIILEYKSEFNQKGEVPVDPDYIIPLGVGEIKRQGTDVTVVTYGKMLRR
                     VVQAAEELAEEGISVEIVDPRTLVPLDKDIIINSVKKTGKVVLVNDAHKTSGYIGEIS
                     AIISESEAFDYLDAPIRRCAGEDVPMPYAQNLENAMIPTVESIKDAIRKTYNKE"
     gene            9549..10592
                     /locus_tag="ACL29Z_001252"
     CDS             9549..10592
                     /locus_tag="ACL29Z_001252"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008808675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0045254 - pyruvate dehydrogenase complex
                     [Evidence IEA];
                     GO_function: GO:0016746 - acyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0006086 - acetyl-CoA biosynthetic process
                     from pyruvate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrolipoamide acetyltransferase"
                     /protein_id="HGR0069563.1"
                     /translation="MADDKLRATPAARKLADDLGINLYDVSGSGANGRVHKEDVETYK
                     DTNVVRISPLAKRIALEHNIAWQEIQGTGHRGKIMKKDVLALLPENIENDSIKSPAQI
                     EKVEEVPDNVTPYGEIERIPMTPMRKVIAQRMVESYLTAPTFTLNYEVDMTEMLALRK
                     KVLEPIMEATGKKTTVTDLLSLAVVKTLMKHPYINASLTEDGKTIITHNYVNLAMAVG
                     MDNGLMTPVVYNAEKMSLSELVVAFKDVIGRTLDGKLAPSELQNSTFTISNLGMFGVQ
                     SFGPIINQPNSAILGVSSTIEKPVVVNGEIVIRPIMSLGLTIDHRVVDGMAGAKFMKD
                     LKELIETPISMLI"
     gene            10638..12341
                     /gene="lpdA"
                     /locus_tag="ACL29Z_001253"
     CDS             10638..12341
                     /gene="lpdA"
                     /locus_tag="ACL29Z_001253"
                     /EC_number="1.8.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003001382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004148 - dihydrolipoyl dehydrogenase
                     activity [Evidence IEA];
                     GO_function: GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrolipoyl dehydrogenase"
                     /protein_id="HGR0069564.1"
                     /translation="MALEVIMPKAGVDMTEGQIVQWNKKVGEFVKEGEILLEIMTDKV
                     SMELEAEEDGYLIAILKGDGETVPVTEVIGYLGEERENIPTAGAASPEASPVPVASTS
                     NDDGKSDDAFDIVVIGGGPAGYVAAIKAAQLGGKVALVEKSELGGTCLNRGCIPTKTY
                     LHSAEIIENIGHAANRGIVIENPNFTVDMEKLLETKSKVVNTLVGGVAGLLRSYGVAV
                     HKGIGTITKDKNVLVNGSELLETKKIILAGGSKVSKINVPGMESPLVMTSDDILEMNE
                     VPESLVIIGGGVVGIELGQAFMTFGSKVTVIEMMDRIVPAMDVEVSKNLRLILERKGM
                     TILTGTKLQEIIEENGQLRIKVEGKDDIIASKALLSIGRMPDLEGIGEVEFELDRGCI
                     KVNEYMETSVPGIYAPGDINGTKMLAHAAFRMGEVSAENALKGNHAVAKLNLTPAAIY
                     TLPEVAAVGLTEEQAREKYDVAIGKFNFAANGRAIASDAAQGFVKVIADKKYGEILGV
                     HIIGPAAAELINEASSIIEMEITVEEMLKTIHGHPTYSEVMYEAFADVLGMAIHSPKK
                     K"
     gene            12405..13394
                     /locus_tag="ACL29Z_001254"
     CDS             12405..13394
                     /locus_tag="ACL29Z_001254"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000873976.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoate--protein ligase"
                     /protein_id="HGR0069565.1"
                     /translation="MKYIINHSNDTAFNIALEEYAFKHLLDEDQIFLLWINKPSIIVG
                     RHQNTIEEINRDYVRENGIEVVRRISGGGAVYHDLNNLNYTIISKEDENKAFDFKSFS
                     TPVINTLAQLGVKAEFTGRNDLEIDGKKFCGNAQAYINGRIMHHGCLLFDVDLSVLAN
                     ALKVSKDKFESKGVKSVRARVTNIINELPKKITVEKFRDLLLEYMKKEYPEMTEYVFS
                     EEELAEINRIKDTKFGTWDWNYGKSPEFNVRRGTKFTSGKVEVFANVTESKIQDIKIY
                     GDFFGIEDVAAVEAVLRGVKYEREDVLKALKTIDITRYFAGISREEIAEAVVG"
     gene            complement(13467..14537)
                     /gene="xerS"
                     /locus_tag="ACL29Z_001255"
     CDS             complement(13467..14537)
                     /gene="xerS"
                     /locus_tag="ACL29Z_001255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000817875.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA];
                     GO_process: GO:0015074 - DNA integration [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine recombinase XerS"
                     /protein_id="HGR0069566.1"
                     /translation="MKREILLERIDKLKQLMPWYVLEYYQSKLAVPYSFTTLYEYLKE
                     YDRFFSWVLESGISNADKISDIPLSVLENMSKKDMESFILYLRERPLLNANTTKQGVS
                     QTTINRTLSALSSLYKYLTEEVENDQGEPYFYRNVMKKVSTKKKKETLAARAENIKQK
                     LFLGDETEGFLTYIDQEHPQQLSNRALSSFNKNKERDLAIIALLLASGVRLSEAVNLD
                     LRDLNLKMMVIDVTRKGGKRDSVNVAAFAKPYLENYLAIRNQRYKTEKTDTALFLTLY
                     RGVPNRIDASSVEKMVAKYSEDFKVRVTPHKLRHTLATRLYDATKSQVLVSHQLGHAS
                     TQVTDLYTHIVSDEQKNALDSL"
     gene            complement(15121..16671)
                     /locus_tag="ACL29Z_001256"
     CDS             complement(15121..16671)
                     /locus_tag="ACL29Z_001256"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000392528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0005247 - voltage-gated chloride channel
                     activity [Evidence IEA];
                     GO_process: GO:0006821 - chloride transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="chloride channel protein"
                     /protein_id="HGR0069567.1"
                     /translation="MEEQSEIVRSKKEFAFASSTILSQVGRGIIVGLIVGIIVGSFRF
                     LIEKGFHLIQGVYQDQGYLVRNLFVLVLFYILICWLSAKLTRSEKDIKGSGIPQVEAE
                     LKGLMSLNWWGILWKKYVLGILAIASGLMLGREGPSIQLGAVGGKGIAKWLKSSPVEE
                     RSLIASGAAAGLAAAFNAPIAALLFVVEEVYHHFSRFFWVSTLAASIVANFVSLLMFG
                     LTPVLDMPDNIPPMTLDQYWIYLVMGIFLGFSGFLYEKAVLNVGRVYDLIGQKIHLDR
                     AYYPILAFILIIPVGIFLPQIIGGGNQLVLSLTEQNFSFQVLLAYFLIRFIWSMISYG
                     SGLPGGIFLPILALGSLLGALVGVICVNLGLVSQEQFPIFVILGMSGYFGAISKAPLT
                     AMILVTEMVGDIRNLMPLGLVTLVSYIIMDLLKGTPVYEAMLEKMLPEEVSSEGEVTL
                     IEIPVSDKIAGKQVHELNLPHNVLITTQVHNGKSQTVNGSTRMYLGDMIHLVIPKSEI
                     GKVKDLLL"
     gene            complement(16687..17466)
                     /locus_tag="ACL29Z_001257"
     CDS             complement(16687..17466)
                     /locus_tag="ACL29Z_001257"
                     /EC_number="3.1.26.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000201102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0004523 - RNA-DNA hybrid ribonuclease
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease HII"
                     /protein_id="HGR0069568.1"
                     /translation="MATIKEIKEFLVTVKELESPIFLELEKDNRSGVQKEISKRKRAI
                     QAELDENLRLESMLSYEKELYKQGLTLIVGIDEVGRGPLAGPVVAAAVILPKNCKIKG
                     LNDSKKIPKKKHLEIFQAVQDQALSIGIGIIDNQVIDQVNIYEATKLAMQEAISQLSP
                     QPEHLLIDAMKLDLPISQTSIIKGDANSLSIAAASIVAKVTRDELMKEYDQQFPGYDF
                     ATNAGYGTAKHLEGLTKLGVTPIHRTSFEPVKSLVLGKKES"
     gene            complement(17453..18304)
                     /gene="ylqF"
                     /locus_tag="ACL29Z_001258"
     CDS             complement(17453..18304)
                     /gene="ylqF"
                     /locus_tag="ACL29Z_001258"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000201313.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_process: GO:0042254 - ribosome biogenesis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase YlqF"
                     /protein_id="HGR0069569.1"
                     /translation="MATIQWFPGHMSKARRQVQENLKFVDFVTILVDARLPLSSQNPM
                     LTKIVGDKPKLLILNKADLADPAMTKEWRQYFESQGIQTLAINSKEQVTVKVVTDAAK
                     KLMADKIARQKERGIQIETLRTMIIGIPNAGKSTLMNRLAGKKIAVVGNKPGVTKGQQ
                     WLKTNKDLEILDTPGILWPKFEDETVALKLALTGAIKDQLLPMDEVTIFGINYFKEHY
                     PEKLAERFKQMKIEEEAPVIIMDMTRALGFRDDYDRFYSLFVKEVRDGKLGNYTLDTL
                     EDLDGND"
     gene            complement(18558..23771)
                     /gene="zmpD"
                     /locus_tag="ACL29Z_001259"
     CDS             complement(18558..23771)
                     /gene="zmpD"
                     /locus_tag="ACL29Z_001259"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000054791.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004222 - metalloendopeptidase activity
                     [Evidence IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="zinc metalloprotease D"
                     /protein_id="HGR0069570.1"
                     /translation="MSLLKKDKFSIRKIKGIVGSVFLGSLLFAPSVVGASTYHYLDYS
                     SLTQTERDQLKQGRPDESKESYALDYEKDALPNTGSSQSIMTALGLLAIGSLIVIITK
                     DNRNKKIATFLIVGATGLVTLSTASALNLNANIHESGRDGVLQISGYRYVGYLELDDK
                     TVSSVSPASTVSPVEQPKVVTEKGEPEVHEKPDYTQPIGANLVEPEVHEKLAYTEPVG
                     TTGVDENGNLIEPPVNDIPEYTEPVGTTGVDENGNLIEPPVSDIPEYTEPISTVSEVA
                     SEREELPSLHTDIRTETIPKTTIEESDPSKFIGDDSVRQVGEDGERQIVTSYEELHGK
                     KISDPVETVTILKEMKPKILVKGTKEKPKEKTAPVLTLDRTNTNVLNRSATLSYHLVN
                     TDGVTINKITATIKDGNEIVKTVDLTSEQLDKQVEDLKFYKDYKIETTMTYDRGKGEE
                     TATLEEKPLRLDLKKVEIKNIASTNLVKVNDDGTETPSDFMTEKPSDEDVKKMYLKIT
                     SRDNKVTRLAVDKIEEVTEEGKKLYKITAEAQDLIQHTDPTKVRNKYVHYIEKPVPKV
                     DDVYYNFKELVDAMNADKNGTFKIGADLNATNVPTPNKQYVPGTFKGHLSSVDGKQYT
                     IHNIARPLFDRVENGSVKNINLGNVDINMPWADGIAPVANMVKNATVEDVKVTGNVVA
                     NNNIAGIVNKIDSGGQLTNVAFIGNLTGVGDKGQYMAGIAGEIWRGNLAKAYVEADIV
                     ANRARIGGLVAKTDNGNDSMGIGKYGSIRKSVTKGTIKTKVLFETGGFINSNLPFGKL
                     EDNISMMRVENGEEFFGSSDLDYDGGYFTNGWLERNFVVKGVSSGKHSYKRSRDKIKE
                     ISQDEANKRIANFGLTADKYEINEPVVNRLNRLTRREDEYKSTQDYKSERDLAYRNIE
                     KLQPFYNKEWIVNQGNKLAEDSNLAKKEVLSVTGMKDGQFVTDLSDIDKIMVHYADGT
                     KEEMDVTKNTDSKVQQVREYSVSGLGDVVYTPNMVVKNRDKLIADVKSQLSSVELISQ
                     EVRDLMSRRDKPAENTDERKNGYIKDLYLEESFAEVKQNLDKLVKSLVENEDHQLNGD
                     EAAIKSLLKKVETNKAKIMMALTYLNRYYDIKYGDISIKNIMMFKPDFYGKTPSVIDR
                     LINIGSSEKNLKGDRTQDAYREIIAGNTGKSNLRNFLEYNMRLFTEDKDINDWFIHSA
                     KNVYVSEPKTTNTELKDKRHRVFDGLDNGVHGRMILPLLTLKDAHMFLISTYNTMAYS
                     SFEKYGKHTEEARNEFKTKIDEVAHAQQTYLDFWSRLALPNVRDRLLKSQNMVPTPVW
                     DNQTYNGSPVGRRGFDSKGNPIAPIRELYGPTWRYHDRDWRMGAMASIFPNPNNDDKV
                     LFMVTDMISPFGISAFTHETTHVNDRMLYFGGHKHRQGTDVEAYAQGMLQTPDSSTTN
                     GEYGALGINMAYHRPNDGNQWYNPDPDKLKTRDDIDRYMRNYNEAMMLLDHVEADAVL
                     PKIKGDNSKWFKKIDKEMRSKIQYNDLLGPNQWDSIRDLKDEEKVMTLSSVNDLVDNN
                     FMTKHGNPGNGRYRPEDFTPNSAYVNVNMMAGIYGGNTSQGAPGSLSFKHNAFRMWGY
                     YGYENGFISYVSNKYKAEADKNNHGLLSDKLIINKVSKGNFNTLEEWKRHWYGEVLAK
                     AKKGFEAIDIDGVHISNYDELRPLFDKAVEEDLKKPDDFSHTVALKSKVFKALLKNTD
                     GFFNKLFKEDI"
     gene            complement(23815..>26339)
                     /locus_tag="ACL29Z_001260"
     CDS             complement(23815..>26339)
                     /locus_tag="ACL29Z_001260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001845810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005576 - extracellular region [Evidence
                     IEA];
                     GO_function: GO:0004222 - metalloendopeptidase activity
                     [Evidence IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA]"
                     /codon_start=3
                     /transl_table=11
                     /product="ZmpA/ZmpB/ZmpC family metallo-endopeptidase"
                     /protein_id="HGR0069571.1"
                     /translation="KVYKNIEKLLPFYNRETIVKYGNLVETSSNLYNKELLSVVPMKD
                     KEVISDINKNKSSINKLLLYYADNTSETLNVNYQTDFSNVAEYRIGGTNLIYTPNTLL
                     RNYQNILDEVLPALNSVEYKSEAIRKVLDVSKDVSLTELYLEEQFNTTKTNLKDSLTK
                     LLTADAAIAENNNKVIDNYVIEKIKNNKEALLLGLTYLERWYDFKYRDTKAKDLVMYH
                     LDFFGKSNSSALDNVIELGKSGYNNLLAKNNVITYNVLLAKNYKTNNLFDALEKYRKA
                     FVPDKTNNEWFKEQTKAYIVEEKSTIKEVSDKQSIAGSPYSIGVYDRLTSPSWKYPSM
                     VLPLLTLPEKSVFIIANISTIGFGAYDRYRSKEHPAGTDLNDYVEKKAKEAAVRFRDH
                     YDYWYRILDDKNKEKLYRSVLVYDAFRFGTDEKEDKDTYQATFETNHPAIKHFFGPAG
                     NNVVHNSNGAYATGDAFYYMAYRMLDKDGAVTYTHEMTHNSDREIYLGGYGRRNGLGP
                     EFYAKGLLQAPDHPNDPTVTINSILKYDQSEESTRLQVADPTQRFGSVDDLNKYMHNM
                     FDVIYMLEILEGKAVAKLDTNQKYDLLRKIENEYKPDPDGNSVYATNVVRRLKPEELT
                     KLTTFNSLIEHDIITRRGYVDEATYKRNGYYTINLFSPIYSALSSKIGTPGDLMGRRI
                     AFELLAAKGYKDGMVPYISNQYEKEAKAQGKVITSYGKQIGLVTDEIVLSKVFNNQYN
                     SWIDFKKDMYKEREDKFGKLNKVSFIDPNGSWARQQKVTIDNINRLEKMIEDAVKFDA
                     EDEVAKLYPETNSRVLKLKKAIFKAYLDQTGDFRSSIFENKK"
BASE COUNT         7902 a         4973 c         5057 g         8407 t
ORIGIN      
        1 aagaaacaaa aatggtcaag ctgataccaa tcaaacggag aaacctcaga cagaaaaacc
       61 tgaggaagaa acccctcgag aagagaaacc gcaaagcgag aaaccagagt ctccaaaacc
      121 aacagaggaa ccagaagaag aatcaccaga agaatcacca gaggaatcag aagaacctca
      181 ggtcgagact gaaaaggtta aagaaaaact gagagaggct gaagatttac ttggaaaaat
      241 ccaggatcca attatcaagt ccaatgccaa agagactctc acaggattaa aaaataattt
      301 actatttggc acccaggaca acaatactat tatggcagaa gctgaaaaac tattggcttt
      361 attaaaggag aataagtaaa ggtagcagca ttttctaact cctaaaaaca ggataggaga
      421 acgggaaaac gaaaaatgag agcagaatgt gagttctagt tctcattttt ttatgaaaat
      481 gtgcaaaata tagtagattg aaattagaat agtatacctc tacttctaaa acattgttag
      541 aaatcgattt gactgtcctg ttcttatttc attttactat atcttaacag atagtgtaaa
      601 taaagataaa ctatttactg gctaattaat cagttaaaca ctagttaagg agtaatgata
      661 aaaaagaaca atactattat tgatggccag tctgttggct cttgtcttag gagcatgtgg
      721 ttttttggac atattgatcc tggatcattc tcatcaggat tactctttac tgctatttta
      781 gaaactgggg tggtttgatg gaaagtattg gtattggtct tgttatcgtt tcacattcca
      841 aacacattgc agaaggtgtt gttgaactga ttagtaaagt agctaaagat gttccgatta
      901 cttatgtaag aggaaccgag ggcggaggaa ttggaacgag ttttgaacaa gtagataggg
      961 ttgtttccga aaatccagca gatactttac ttgccttttt tgacctaggt tctgctaaaa
     1021 tgaacttaaa aatggtgact gatttcagtg ataaaagtat catcatcaac agggttccaa
     1081 ttgtagaagg tgcctataat gcagctgctc ttcttcaggc tggtgcagaa ctgtcagtta
     1141 ttcaaacaca gttagcggag cttgaaatca ataaataagg aattttacta taactctttt
     1201 tataggtaag ctattgatta tctcaactat aaaatgttaa gtaaatgatt tcaaaatcag
     1261 aaagggattg ctttatgcag ttccttttta ttttaacagg agtgaaacta tagtgtttct
     1321 aaattgtgaa tcaatcaaaa ctgattgtga tggggctatt ctagctttag aaaccttcaa
     1381 aaattaaaat ttaaggcaat caattacttg gaagagtatg aaagcattta gtttatagga
     1441 attctaggtc tagaattaca tatatattta tgaagacggg gtgttcgata gttagtattg
     1501 ttctattctg aaagatttga gctgtcagtt gtatagaaag tgttcgaatt tttttaagtg
     1561 attaaattag ttaattgtat gaggtgcttt atgatataat gttcttaatg aattttcaga
     1621 aaggaaaacc tcaaattgtt ctacaaattt ctactcttcg acctcgacca cactcttctt
     1681 gattttgatg ctgctgagga tgtggctttg acccaacttc taaaagaaga aggagttgcg
     1741 gatattcagg cttataaaga ttattacgtt cctatgaaca aggctctctg gaaagacttg
     1801 gagctgaaga aaatcagtaa acaagagctg gttaacacgc gcttttctcg tttatttgct
     1861 cattttggac aggaaaaaga cggtagtttt cttgcccagc gttaccaatt ttacctcgcc
     1921 cagcagggac aaacactatc gggcgctcat gatctcttgg acagcctcat tgagcgtgat
     1981 tataacttgt atgctgcgac aaatggcatt actgccattc agacaggacg tttggctcaa
     2041 tctggtctag caccttattt caatcaagtc tttatctcag aacagttgca aactcaaaag
     2101 ccggatgctc ttttttatga aaagattggc cagcaaattg ctggatttag taaagaaaag
     2161 acgctgatga ttggagattc tctaaccgcc gacattcaag gtggcaataa tgcggggatt
     2221 gacactatct ggtataatcc tcatcacctc gaaaatcaca cacaagccca gccgacttac
     2281 gaagtctatt cttaccaaga cttgctggat tgtttagata aaaatattct tgaaaagatc
     2341 acattttaaa ggagacgagc taatgactac aaaaaagcta atattactat tgaagagtac
     2401 attgaaatgt ctgaagttga ttttaatgaa gctgttaatt atgaatttac atctgacact
     2461 tgtcaattag caaatagtat ttatcaatct ctttttaagt tttttgataa gaaaaatttc
     2521 tctggcgatt taatttttac ttggaaatct ccatcattag tcaaagaagg ggattatatt
     2581 gggagaaggg attcacaagt agataatctt agagtaatag gaaatatatt tccgaattat
     2641 cttactaatc gaaaatatag cctcaatatg aatcgtaatg gctgtatagg agattttcct
     2701 catgactttt ttgatacata cctagatcat gtagcaaaat atgcctacga acaaaaagtt
     2761 aataatatta aagagtatta tcctttaaaa agagcgattt tacaccaaga gaatgcattg
     2821 tattttcgat tgttttctaa ttttgacgac tttttagaaa aaaattattt aaagactata
     2881 tggcaagttt ctaaagaaac tcctttttct gaaatggatt ttaatatgtt taaaaatatt
     2941 tcagaaaaga taatcttcga aagaggtagt aaaatgctta atgatttaaa aagtaattat
     3001 aaaaaatagc cagtctttat aaactgtatt cacgtattca aatcgtatat atagtcgatt
     3061 tattaaatct ttagataaac tgtaaaaagt ggtttccata gccacttttt gctataatag
     3121 aggcagtaaa aatgaaggag tcagctatgg aacactcgtc ttggcacgct ttgattaagg
     3181 cgcaattacc tgagggttat ttcgggaaaa tcaatcagtt tatggagcag gtctattctc
     3241 aggggactat ttatccaccc aaggaaaagg tttttcaggc tctcttgaca acactgcttg
     3301 aagaagttaa ggtggtaatt ctagggcaag acccctacca cggaccaggt caagcgcagg
     3361 gcttgagttt ttctgtacct gactctatcc cagctccacc atccttgcaa aatatcttga
     3421 aagaattgtc agatgatatc ggagttaaga aatctcatga tttgacagct tgggctgagc
     3481 aaggagtctt gcttcttaat gcttgtttga ctgttcctgc tggacaggcc aatggtcatg
     3541 ctggtcaaat ctgggagcct tttactgatg ctgtgattca ggtggtcaat catctagata
     3601 gaccagtcgt ttttgtactc tggggagctt atgcacgtaa gaagaaggca ttagttacca
     3661 atcctcatca cttgattatc gaatcagccc atccaagtcc tttgtcggtt tatagaggat
     3721 tttggggttc caagcccttt tccaaggcca atgcattctt aaaagagaca ggacaagagc
     3781 caatcgattg gcttagataa ggagaaaata tgcctcagtt agcgacgatt tgctacattg
     3841 ataatgggaa agaactgctc atgctccatc gtaataagaa acccaatgat gtccatgaag
     3901 ggaaatggat tggtgtgggt ggtaagctag agagaggaga gacgccccag gaatgcgcgg
     3961 tacgtgaaat ccttgaagaa acagggctca aagccaagcc agttctaaaa ggtgtcatca
     4021 cttttcctga atttacacca gatttagact ggtacaccta tgtttttaag gtgacggagt
     4081 ttgagggcga cttgattgac tgcaatgagg ggatgctaga atgggttccc tatgatgagg
     4141 ttttgagcaa gccgacttgg gaaggtgacc acacctttgt tgagtggctt ttagaggata
     4201 aacccttctt ttcagccaag tttgtttatg atggggataa attgttggat acccaagttg
     4261 atttctatga ataaaggaga aagcagatgc tactaatcaa aaatggtcgt gtaatggatc
     4321 ccaagtctgg tttggatcaa gtttgtgatg tcttagttca agatgggaaa attatcaaaa
     4381 ttgcgcctga gatcacggaa gaaggagcag aaacgattga tgctactggt catgtggttg
     4441 ctcctggttt ggtcgatatt catgtgcatt tccgtgaacc tggtcaaaca cataaagaag
     4501 acattcatac tggtgcccta gcagccgctg caggtggttt tactactgtc gtcatgatgg
     4561 ctaataccag tccaaccatt tcagacgtgg agactttgca agcagttctc cagtcagctg
     4621 ccaaagagaa gattaatgtc aagacagttg cgaccattac taaaaacttt aatggtaaaa
     4681 acttgactga ctttaaggca cttttagaag ctggtgcggt tggtttctct gatgacggta
     4741 ttccgcttga gagcagtaag attgtcaagg aagccatgga ggaagccaaa aaactcaata
     4801 cctttatcag ccttcatgag gaagatccag gtttgaacgg tgttcttggc tttaatgaaa
     4861 atattgctag agaacatttc catatctgtg gtgctactgg ggtggctgag tacgctatga
     4921 tggcgcgtga tgtcatgatt gcctatgcaa ctaaagccca tgttcacatc cagcatttgt
     4981 ctaaggaaga aagtgttaaa gtagtggagt ttgctcaggg gttaggtgca gaagtcacag
     5041 cagaagtagc accacagcat ttctctaaga cagaagcact tcttttaaca caaggtagca
     5101 atgctaagat gaatccaccg cttcgtttgg aatcagaccg tcgtgccgtt atcgaaggtc
     5161 tcaaatcagg tgtcatcaca gttattgcga ctgaccacgc gcctcatcat gtagatgaaa
     5221 aaaatgttga agatattacc aaagcgccat ctggtatgac tggcttagaa acatccctgt
     5281 ctctcggctt gacctatttg gtagaagctg gtgagttgag cttgatggaa ttacttgaaa
     5341 aaatgacata caacccagcc aagctttaca actttaaagc aggttacttg gctgagaatg
     5401 gtccagcaga tatcactatt tttgatgcca aggctgaccg ccttgtggac tcccattttg
     5461 cttccaaagc agctaattca ccattcatcg gtgaaacctt aaaagggcag gttaaatata
     5521 ccatctgtaa gggacaaatc gtctatcaag cttgatagga gttagaatat gaattatttt
     5581 cgaaaacgta gggagagaca agcgaaatct aatagtggaa tttactgtcc cgcagctaat
     5641 cgttccaaaa ttcaatatga aactaaagaa aaagctgacc atgcggttca atatgataac
     5701 ggaggtttag ttagaagcta ttattgtcgt acatgtgcgt gttggcatac tacttcaaaa
     5761 tctaataaac ctccgctaag tttgaaaaac tatggtctga aactctttgg tttagataaa
     5821 tcagaataga aagagaagta tgtataagac aaagtgttta cgagagaagt tagtattatt
     5881 tttaaaaatt ttcttcccaa tcctgattta ccaatttgcc aattattctg cctcttttgt
     5941 tgatactgca atgacaggtc aatacaacac tatggacttg gctggtgtat ctatggcaac
     6001 cagtatctgg aatcctttct ttacatttct aacagggatt gtgtcagcct tggtgcctat
     6061 cattggtcac catcttggtc gaggcaaaaa ggaagaagtt gcgtctgatt tttaccaatt
     6121 tatttatttg gccttgggcc tatctgtggt cttgctgggg atggtacttt tcttggcacc
     6181 aacaatcttg aatcatattg ggttagaagc agcagtagcg gcagtagcgg ttcgctatct
     6241 ttggttttta tctatcggga ttatcccctt gttgctcttt agcgtcattc gttccttgct
     6301 ggattcgctg ggcttgacca aactgtccat gtacctcatg cttttgttac tccctctcaa
     6361 tagcggattt aactatctct tgatttacgg tgcctttggt gttccagaac tgggaggggc
     6421 tggtgctggt ttaggaacat ccttggccta ctgggtcttg cttgggattt ctgttctggt
     6481 tttatttaaa caggagaagc tcaaagcctt acaccttgag aaacgaattc cacttaatat
     6541 ggataacatt aaggaaggag ttcgtttagg tctgcctatt gggggaactg tcttcgcgga
     6601 agtggctatc ttttcagtgg ttggcttgat tatggctaag ttttcgtcct tgattatagc
     6661 tagtcaccag tcagctatga acttttcaag tcttatgtac gcctttccta tgagtatctc
     6721 atcggctatg gctattgtcg tttcctatga agtgggagcc aagcgatttg atgatgcgaa
     6781 aacctatatt ggtctaggaa gatggactgc cctcattttt gcggccttca ccttaacctt
     6841 cctttacatt tttaggggaa atgtggccag tctttatggt aacgacccaa aatttatcga
     6901 tttgacagtg cgttttttaa cttatagtct tttcttccag ttagcagata cctttgcggc
     6961 gccgcttcag ggaattttgc gggggtataa ggatacagtt attccttttt accttggttt
     7021 gcttggttat tggggcgtag caatccctgt ggctacgcta tttgattctc taacagattt
     7081 tggagcttat tcttactgga tcggcttgat tattagtttg attgtgagtg gggcgctcta
     7141 ccgttggcgt ttaactgtga ttatgaagag atttgaatct ttagcaaaat ccaaatgcta
     7201 aaaagtttgt gaaaaaatat tcttgacaag aaaatccctt gttttcacgg ggttttcttt
     7261 tttattttgt gaaatttctt ttagaaaaac tttgacagta tttgccaaaa acggtaaaat
     7321 agtaaggtaa gaagaaagtt agaaaggcaa gaagatgtca actttagata aaaatctttt
     7381 gctagaaatg ttccgtaaga tggaagaaat ccgtcgcatg gacttaaaaa ttgcacaatt
     7441 agtaaagaaa gggaaagtgc caggaatgac gcacttttct gttggtgaag aggcagctaa
     7501 cgtgggggct atgttagctc tcaatccaga tgatctgatt acctcaaacc accgtggaca
     7561 cgggcaagct attgctaaag ggattgacct caacggaatg atggctgaaa tccttggtaa
     7621 atacactgga acctgtaaag ggaaaggtgg atctatgcat atcgctgacc ttgatgctgg
     7681 gaaccttggt gccaatggta tcgtaggtgg tggtatgggg atcgctgtcg gtgcagccct
     7741 cagtcagcaa atgcaaaata ccggtaaaat cgttgtctgc ttctttggag atggtgcgac
     7801 caatgaaggt gttttccacg aagcagtgaa catggcttct atctggaacc tgccagtcat
     7861 tttctattgc attaacaacg gttacggtat ctctgcggat atcaagaaaa tgaccaatat
     7921 agaacatatc catcaacgta gcgccgctta tggaattcct ggaatgttca tcgaagacgg
     7981 taacaatgtc atcgatgtct atgaaggatt tcagaaagct gtagaccatg ttcgcagtgg
     8041 caatggtcca gtcttgattg aaagtgtaac ttatcgctgg ctcggtcact catcatctga
     8101 ccctggtaaa tatcgtacgc gtgaagaagt ggaattgtgg aaacaaaaag atccaatcga
     8161 aaacctccgc aattacctta ttgaaaataa cattgcaagt gccgaagaat tggaagaaat
     8221 ccaagcgcaa gtaaaggaag cagtagaagc ttctgttaaa tttgcagagg aaagcccatt
     8281 cccaccgctt gaatcagcct ttgaagatat ttacgcagac taaggagaaa gagataaaat
     8341 ggaaacaaaa acaatgtcct tccgtgacac cattatcctt gctatgtctg aggaaatgcg
     8401 tcgcgatgaa aatgtgttct tgatgggaga agacgtcggt gtcttcggag gagacttcgg
     8461 tacttctgtt ggaatgcttg aagaatttgg tccagaacgt gtccgtgact gtccgatttc
     8521 tgaagctgcc atctctggag cagcagcagg agcagccatg acaggacttc gtccaatcgt
     8581 cgatatgacc ttcatggact tctctgttat tgccatggac aatatcgtca accaagctgc
     8641 taaaacacgt tacatgtttg gtggtaaagg tcaggttcca atgactgttc gttgtgcagc
     8701 tggtaacgga gttggctctg ccgcccagca ctcacaatct ctagagtctt ggtttactca
     8761 cattccagga cttaaggttg tggcacctgg aacacctgcg gacatgaaag gcctgcttaa
     8821 gtcttctatc cgtgataaca acccagttat tatacttgag tacaagtcag aatttaacca
     8881 aaaaggggaa gtgccagttg atccagacta cataattcca cttggggttg gtgaaatcaa
     8941 acgccaagga acggatgtaa cagttgttac ttatggaaaa atgcttcgcc gtgtggttca
     9001 agctgctgaa gaattagcag aagaaggaat ttcagttgaa attgttgacc cacgtaccct
     9061 tgttccgctt gataaggata tcatcataaa ctcagtgaag aagactggta aggttgttct
     9121 ggtcaacgat gcccacaaaa caagtggcta tatcggtgaa atttcagcta ttatttcaga
     9181 atcagaagca tttgactatc tagatgcacc aatccgccgt tgtgcaggag aagatgtgcc
     9241 gatgccttat gcacaaaacc tagaaaatgc aatgattcca acagttgaaa gtatcaaaga
     9301 tgcaatccga aaaacttata acaaagaata gagttacata agataagtta tgtaaataaa
     9361 ataaagctga cgagaaactt tgtatctttt aggtgcagag ctcttcgtca ttaatatctt
     9421 atattcgagc acgggctaaa agctcggaaa aaagataaat ctccttggct tcatcgaagc
     9481 catcgtcgat ttcctatttt tcagtcgctt ttgacgccct ttgtatcata aatagaattg
     9541 gagaggtcat ggctgatgac aagctaagag cgactcctgc agctagaaag ttagcggatg
     9601 atttagggat aaacctctac gacgtttctg gctcaggtgc aaacggtcgt gtccacaaag
     9661 aagacgtgga aacttataaa gacacaaacg tggttcgcat ttcgccactt gcaaaacgaa
     9721 ttgccctcga acataacatt gcttggcagg aaatccaagg aaccggtcat cgtggtaaaa
     9781 tcatgaagaa ggatgttttg gccctgcttc ctgaaaatat cgaaaacgat agcatcaaat
     9841 ctcctgctca gattgaaaaa gtggaagaag tccctgataa cgtaacacca tatggtgaaa
     9901 tcgagcgtat tccaatgaca ccaatgcgta aggttattgc ccaacgcatg gttgaatctt
     9961 acttgactgc gccaaccttc accctcaact atgaagttga tatgactgaa atgttggctc
    10021 ttcgtaagaa ggttcttgag ccaatcatgg aagcaactgg gaagaagact actgtaacag
    10081 accttctttc gcttgcagtt gttaagactc ttatgaaaca cccatacatc aacgcttcat
    10141 tgacagaaga tggcaagact attatcactc acaactatgt caatcttgcc atggcagttg
    10201 ggatggataa tggattgatg acacctgttg tttacaatgc tgagaagatg agtctttcag
    10261 aactggtggt agcctttaag gatgttattg gccgtacctt ggatggtaaa ttggctccaa
    10321 gtgagttaca aaattcaaca ttcacaatca gtaatttggg aatgtttggt gttcagtcct
    10381 ttggtccgat tattaaccaa cccaactcag ctatccttgg tgtcagttcg acaatcgaga
    10441 agccagttgt cgtcaatggt gaaattgtga ttcgcccaat catgagttta ggattaacca
    10501 ttgaccaccg tgtcgtagat ggtatggctg gtgctaagtt tatgaaggac ttgaaagagt
    10561 tgattgaaac gccaatctca atgttaattt aagagcaaga gtattcattt ttaagatata
    10621 gataaaggaa ggaagacatg gccttagaag taattatgcc aaaagccggc gtggatatga
    10681 cagaaggaca aatcgtccaa tggaataaaa aagtcggaga atttgtaaaa gaaggagaaa
    10741 tccttttgga aatcatgact gataaagtca gcatggaatt ggaagccgaa gaagatgggt
    10801 acttgattgc cattctcaaa ggagatggtg aaactgtccc tgtaacggaa gttatcggtt
    10861 accttggtga agaaagggaa aacatcccaa cagctggagc agcatcgcca gaagctagcc
    10921 ctgtacctgt agcaagtacc tcaaacgatg atggtaagag cgatgatgct tttgatatcg
    10981 ttgtgattgg tggaggtcct gctggttatg ttgcagccat taaagctgcc caactcggcg
    11041 gtaaggttgc ccttgttgag aaatctgaac ttggtggaac ctgcttaaac cgtggatgta
    11101 ttccaaccaa gacctacctt catagcgctg aaattattga aaatatcggt catgctgcaa
    11161 atcgtggtat cgtgattgaa aatcctaact tcactgttga tatggaaaaa cttttagaaa
    11221 ctaaatctaa agttgttaat actcttgttg gtggtgttgc aggacttctt cgtagctacg
    11281 gagttgctgt tcataaagga attggtacaa tcactaaaga caagaacgtc ttggtaaatg
    11341 gttctgaatt gcttgaaacc aagaaaatca ttcttgctgg tggttcaaaa gtcagcaaga
    11401 tcaacgtccc tggtatggaa tctccacttg tcatgactag tgatgacatt cttgaaatga
    11461 acgaagtgcc agaaagtctt gttatcatcg gtggtggagt tgtcggtatc gaactcggtc
    11521 aggccttcat gacatttggt tcaaaagtga ctgttatcga aatgatggac cgtatagttc
    11581 cagctatgga tgtggaagtt tctaagaacc ttcgcttgat ccttgagcgt aaaggaatga
    11641 ccatcttgac tggtactaaa ctgcaagaaa tcattgagga aaatggtcaa cttcgtatca
    11701 aggttgaagg aaaagacgat atcatcgcaa gcaaagctct tctttcaatt ggtcgtatgc
    11761 cagaccttga aggtattgga gaggttgagt ttgaattgga tcgtggttgt atcaaggtca
    11821 acgaatacat ggaaacttca gttccaggca tttatgcacc aggtgacatc aacggtacta
    11881 agatgttggc tcacgcagct ttccgcatgg gtgaagtttc cgctgaaaat gcccttaaag
    11941 gaaatcatgc agttgccaaa ttgaatttga ctcctgcagc catctacact cttcctgaag
    12001 tagcagcagt aggtttgaca gaagaacaag cccgtgagaa atacgatgtt gccatcggta
    12061 agtttaactt tgctgctaac ggtcgtgcta ttgcatctga cgcagctcaa ggtttcgtaa
    12121 aagttatcgc tgataagaaa tacggagaaa tccttggtgt acacattatt ggtcctgcag
    12181 ccgcagaatt aataaacgaa gcatcaagca tcatcgaaat ggaaatcact gttgaggaaa
    12241 tgctgaagac catccacggg cacccaactt actctgaagt gatgtacgaa gcgtttgcag
    12301 atgttctagg aatggccatc cattcaccta agaaaaaata aaacgaagat agattagact
    12361 ggaaggttat ttccagtttc tatcatataa agtaaaggga tatcatgaaa tacattatca
    12421 atcattcaaa tgacactgct tttaatattg ccttggaaga atacgccttt aaacaccttt
    12481 tggatgagga tcaaatcttc ctactttgga ttaacaagcc atctatcatt gttggtcgtc
    12541 accagaacac tatcgaagaa atcaaccgtg attatgttcg cgaaaatggt attgaggtag
    12601 ttcgccgtat tagtggtggt ggagctgttt accacgattt aaataacctc aactacacga
    12661 tcatctccaa agaagatgaa aataaggcat ttgacttcaa gagcttctca actccggtta
    12721 tcaataccct ggctcaactc ggggttaaag ctgagttcac aggtcgtaat gaccttgaga
    12781 ttgatggtaa gaagttctgt ggcaatgccc aagcctatat caacggccgt atcatgcacc
    12841 acggttgctt gctctttgac gttgatttgt cagtcctcgc aaatgccctt aaggtttcaa
    12901 aagataaatt tgaatcaaaa ggtgtgaaat ccgtccgtgc ccgtgtaacc aatattatca
    12961 atgaattacc aaaaaaaatc acagtcgaaa aattccgtga tttactcttg gaatacatga
    13021 aaaaagagta cccagagatg actgaatacg tcttttcaga agaagaattg gccgaaataa
    13081 atcgcatcaa ggatactaag tttggaactt gggactggaa ctatggtaaa tcacctgaat
    13141 ttaacgtccg tcgtggaacc aaattcacta gtggtaaggt tgaagtcttt gctaacgtta
    13201 ctgaatcaaa aatccaagac atcaagattt atggtgactt ctttggtatt gaagacgttg
    13261 ctgcagtaga agctgtcctt cgtggggtga aatacgaacg tgaagatgtt cttaaggcgc
    13321 taaaaaccat tgatatcaca cgctacttcg ctggtattag ccgtgaagaa atcgctgaag
    13381 cggtagttgg ataaatcaaa aagaagttgg ccaactaacc aacttctttt tttgatattt
    13441 atttacataa tttaaaatac gtaaaatcat aaactatcca gagcattctt ttgttcatca
    13501 ctaacaatat gggtatagag gtcagtgact tgtgtgctag catgtcctag ttggtgactg
    13561 actaaaactt gtgatttagt cgcatcatag agcctagttg ctagtgtatg gcgcagttta
    13621 tggggtgtta cacgcacttt aaaatcctct gagtatttag caaccatttt ctcaacgcta
    13681 gaagcatcga tacgattagg aacacctctg tagagagtta aaaaaagggc tgtatctgtt
    13741 ttttccgttt tatagcgttg attccgaatg gccagataat tctctaaata aggtttagca
    13801 aaagcagcga cattgactga gtcacgtttg ccaccttttc gagtaacatc aataaccatc
    13861 atttttagat tgagatctct tagatctaga ttaacagctt cagataagcg aacaccagat
    13921 gccaagagaa gggcaataat ggctaaatct cgttctttat ttttgttgaa tgatgagaga
    13981 gctcgatttg aaagctgttg tgggtgctct tgatcgatat aagttagaaa accttctgtt
    14041 tcatcaccta gaaagagttt ttgcttgata ttttcagctc tggcagcaag ggtttctttc
    14101 tttttcttgg ttgaaacttt tttcattaca ttacgataga aataaggttc cccctgatcg
    14161 ttttcaacct cctcggttag atacttgtaa agactagaaa gtgctgataa ggttcgattg
    14221 atagttgtct gtgaaacacc ttgttttgtt gtattagcat tcagcaaggg acgttcacgt
    14281 agataaagga taaaggattc catgtctttc ttagacatat tttccaaaac tgataaagga
    14341 atatcggata ttttatcagc gtttgaaata ccagactcca aaacccagct gaaaaatcgg
    14401 tcatattcct taaggtattc gtacagggtt gtaaaactgt agggcacagc cagtttagat
    14461 tggtagtatt ccagaacata ccagggcatg agttgtttta gtttgtcgat tcgttccagt
    14521 aaaatctcac gtttcatgta ttttctccat aattaagtat actagtagta tagcatagac
    14581 ttgtatattt ttcaagaaaa ttatagtttt tctgaaagat gttataggag tttttcaaag
    14641 tgataaaaag acttagacct acaaacaaaa cagaataagg aaaataataa aaatctcacc
    14701 cactaaactt ctgttaatac tacataactg aagagctata taaggagcta tgagatacaa
    14761 aacacattgt ataatagatt gaaactagaa tagtacatct ggacttctaa aacattgcta
    14821 gaaattgatt tgattgtcct gattgtttta tcctatttct atttcatttc tctatataat
    14881 tgctattgtt ttctttttca tgattttaat cttactgtac agatttgata cagtaaactc
    14941 ctttctagct ttatacttta tcatttctaa cttaattata gtcttatttt taataaagtt
    15001 caattattta tatgtaaaaa tcctcatcag taaaaaataa ccgatctcat ttctgagaat
    15061 cggttttcta aataaatcaa accgatcatt tacataacat aaattatgta aatgatcata
    15121 ctacaacaac aaatctttga cttttccaat ttcacttttt ggaataacca ggtgaatcat
    15181 atcacccaga tacattctgg ttgagccgtt aaccgtttgg ctcttgccat tatggacttg
    15241 agttgtgatg aggacgttgt gtggtaagtt gagttcatga acttgtttcc cagcaatttt
    15301 atcagaaact ggtatttcga taagtgtaac ttctccttcg ctagatactt cttctggaag
    15361 cattttttcc agcatggctt catagactgg cgtacctttg agcaaatcca tgataatata
    15421 agaaacaaga gtgacaagac caagtggcat aaggttgcga atatctccta ccatctcagt
    15481 tacgaggatc atagcggtta agggagcttt tgatatggct ccaaaatagc cactcattcc
    15541 tagaatgaca aatataggga attgctcttg actgacaagt ccaagattga cacagataac
    15601 accaactaag gcaccaagca aagaaccaag agctaaaatg gggaggaaaa ttcctcctgg
    15661 cagtccactt ccatagctaa tcatactcca aataaagcgg attaaaaagt aagctaataa
    15721 aacttggaaa ctaaaatttt gttcagttaa agaaaggaca agctgatttc cgccaccaat
    15781 gatttgaggt aagaagattc cgactggtat gataaggata aaagccaaga tgggataata
    15841 agccctatcc aaatggattt tttgaccaat caagtcataa actcttccaa cgtttaatac
    15901 agctttctca tagagaaaac ctgaaaatcc aaggaaaatt cccatgacga gatatatcca
    15961 atactgatct agggtcatgg gaggaatgtt atctggcata tccaatactg gtgtcaaacc
    16021 gaacatgagt agagacacaa agtttgctac gatgctggct gctagagttg agacccagaa
    16081 aaagcgcgaa aaatggtgat agacttcttc tacaacaaag agaagtgctg caataggagc
    16141 attaaaggct gcggctaaac ctgctgcagc tccactggca atcaaggaac gttcctctac
    16201 tggactggat ttgagccact tggcaattcc tttaccacca actgctccaa gttgaatact
    16261 gggtccctct cgacccagca tgagtccact ggcaatagca agaataccta gcacatattt
    16321 tttccaaaga atgccccacc agttgaggga catgaggcct ttcagttcgg cttcgacttg
    16381 aggaattcct gagcctttaa tatctttttc tgaccgtgtt agtttggcac tgagccaaca
    16441 gatgagtata taaaacaaaa ccagtacaaa aagattgcgc actaagtacc cttgatcttg
    16501 ataaactcct tgtatcaggt ggaagccctt ttcaattaag aaacgaaagg atccgacgat
    16561 aattccaacg atgaggccga caatgattcc tcgaccaact tgggatagta tagtgctgga
    16621 tgcaaaggcg aattctttct tagaacggac tatttccgac tgttcctcca tggtatttcc
    16681 tttcaattaa ctttcttttt tacctaaaac cagtgattta acgggttcaa agctggttcg
    16741 gtgaattggg gtaactccta gttttgtgag gccttccaga tgtttagctg tgccatatcc
    16801 tgcattagta gcgaaatcat agccagggaa ctgctgatcg tattccttca tcaattcatc
    16861 acgtgttacc ttggctacta tagatgctgc tgcgatagag agggagttgg catctccttt
    16921 gataatggag gtttgtgaaa tgggcaagtc cagtttcatg gcatcaatca aaaggtgctc
    16981 tggttgaggg ctgagctggg agattgcttc ttgcatggct agtttggttg cttcatagat
    17041 gttgacttgg tcgatgacct gattatctat gataccaatt ccaatcgaca aggcttggtc
    17101 ttgaacggct tggaaaatct ccagatgttt ctttttagga attttcttgc tgtcgttgag
    17161 acctttaatc ttacaatttt taggtaaaat gacggccgca gcgactacag gaccagcaag
    17221 aggaccacga ccaacctcat caatacctac aattaaggtc aatccttgct tataaagttc
    17281 tttttcataa gaaagcatgg attccaagcg caaattttca tctaattcag cttgaatggc
    17341 tcttttacgc ttgctgattt ccttttgaac tcctgagcga ttatcctttt caagctctaa
    17401 aaaaataggg ctttctaact ccttgactgt cacaaggaat tctttgattt ctttaatcgt
    17461 tgccatcgag gtcttccaat gtatctaagg tatagttacc gagtttgcca tcacggactt
    17521 ccttcacgaa gagactgtaa aaacggtcat agtcatcacg gaaaccgagg gcgcgggtca
    17581 tatccataat aatcacaggc gcttcttctt caattttcat ttgtttgaag cgttcagcca
    17641 gcttttctgg ataatgttct ttgaaataat tgataccaaa aatggtaacc tcatccatag
    17701 gaagcaactg atccttgata gctccagtca atgccaactt aagtgcaaca gtttcatcct
    17761 caaacttagg ccagagaatc cccggtgtat ccaagatttc caggtcttta ttggttttaa
    17821 gccattgttg accttttgtg acccctggct tgtttccaac aacagcaatc tttttaccag
    17881 ccaaacggtt catcagagtt gatttaccag cgtttggaat cccgataatc atagtacgca
    17941 aggtttcaat ctgaatccca cgttctttct ggcgagcaat cttatcagcc atgagcttct
    18001 tggccgcatc tgttacaact tttacagtca cttgctcctt ggagttgata gccagagttt
    18061 ggattccttg tgattcaaaa tactgacgcc attccttggt cattgctgga tcagccaaat
    18121 ccgccttatt taaaatcaag agttttggtt tatcaccaac aatcttggtc aacataggat
    18181 tttgactaga tagaggtaag cgtgcatcca ccaaaatcgt tacaaaatca acaaatttta
    18241 aattttcctg cacctgtcga cgcgctttag acatgtgacc aggaaaccat tgaatagtag
    18301 ccattgagtt tttttccttt cgtagcaagg gtttagagat cctattttat tttactatcg
    18361 tttgaacata aagggttctc aaatgaatga tgtttaaaca gttttttgtt ttatgacata
    18421 gaaatctacc ttatattata tcatgccttc tttattttgt ccgatgatag cctttcaagt
    18481 accctatata gaaaaaagcc atcaaatgat gacttttcag agggagcaaa aaactgttcc
    18541 ttctatattc taaacattta aatgtcttct ttaaacagtt tattaaagaa accgtctgtg
    18601 tttttaagaa gggctttgaa gaccttagat ttaagagcaa cagtgtgaga gaagtcatct
    18661 ggtttcttca aatcttcttc aactgcttta tcaaataaag gccttaactc atcatagtta
    18721 ctgatatgga cgccatcaat atcgatagcc tcaaaacctt tcttagcttt agcaagaact
    18781 tccccgtacc aatgtctctt ccactcttca agagtattaa agtttccttt cgatacttta
    18841 ttaattatta gcttatcgct tagtaaaccg tggttgtttt tatctgcttc tgctttgtat
    18901 ttatttgata cataactaat aaagccattt tcataaccat aatagcccca catacggaaa
    18961 gcattgtgct taaatgataa tgaaccagga gcaccttgac tcgtattccc accgtaaatt
    19021 cctgccatca tattgacatt tacgtaagct gagtttggtg taaaatcttc tggtctataa
    19081 cgtccattac ctggatttcc atgttttgtc atgaagttat tatccactaa atcattgacg
    19141 ctagataaag tcattacctt ttcttcatct ttcaaatcac ggatactatc ccattggttt
    19201 ggacctaaaa gatcattata ctgaatctta gagcgcattt ctttgtcaat cttcttgaac
    19261 cacttactat tgtctccttt aattttagga agtacagcat cagcttctac atgatcaagc
    19321 aacatcatag cttcattgta gtttctcatg tagcggtcaa tgtcatcacg tgtctttaat
    19381 ttgtcaggat ctgggttgta ccattggtta ccatcatttg gacgatggta agccatgtta
    19441 attccaagtg cgccgtattc accattagtc gttgagctgt caggtgtttg caacatacct
    19501 tgagcatagg cttcaacgtc tgtaccttga cgatgcttat gaccaccgaa gtaaagcatt
    19561 ctatcgttta cgtgtgttgt ttcgtgagta aaggctgaaa taccaaatgg gctaatcata
    19621 tccgtcacca taaacaagac cttgtcatca ttatttggat tagggaatat tgatgccata
    19681 gcgcccatac gccagtctct atcatggtat cgccatgttg gaccatataa ttcacgaatt
    19741 ggagctatag ggttaccttt actgtcaaat cctcgacgac ctacaggaga accattgtag
    19801 gtctggttat cccaaactgg tgtcggtacc atattttgac tcttaagaag tctatcacga
    19861 acattaggca gagctaatct ggaccagaaa tctaaataag tttgttgagc atgtgcaact
    19921 tcatcaatct tagttttgaa ctcattacga gcttcttctg tatgttttcc atatttctca
    19981 aatgaactgt acgccatcgt gttatatgtt gaaattaaga acatatgggc atctttaagc
    20041 gttagaagtg gtaaaatcat acgaccatga acaccgttat ctaaaccatc gaacacacga
    20101 tgacgtttat ctttcaactc tgtatttgtt gtcttaggtt ctgaaacata aacattctta
    20161 gctgagtgga taaaccaatc attgatgtct ttatcctctg taaacagacg catgttgtat
    20221 tctaagaagt tacgcaaatt acttttacca gtattacctg cgatgatttc acggtaagca
    20281 tcctgagtcc gatccccttt caagttcttt tcacttgaac cgatgttgat gagtctgtca
    20341 ataacacttg gtgttttacc ataaaaatca ggtttgaaca tcatgatgtt ttttatactt
    20401 atgtcaccgt atttgatatc atagtaacga ttgagataag tcagagccat catgatttta
    20461 gctttattgg tttccacttt cttgagaagt gattttatcg cagcttcatc accattcaat
    20521 tgatggtctt cattttcgac caaggatttg actaacttat ctagattttg cttcacttcg
    20581 gcaaagcttt cttctaagta tagatcttta atataaccat tcttacgttc atccgtattc
    20641 tctgcaggtt tatcacgtct actcattaaa tctcttactt cttgtgaaat caattccaca
    20701 cttgataatt gagatttaac atcagcaatc aatttatcac gatttttaac aaccatattc
    20761 ggtgtataaa caacatcacc aagaccagat acactatatt cacgcacttg ttggacttta
    20821 gaatcagtat tcttagtaac atccatttct tccttagtac catcagcata gtgaaccata
    20881 atcttatcaa tatctgataa atcggtcacg aattgaccat ccttcatccc cgtaacagaa
    20941 aggacttctt tcttagctaa gtttgaatct tctgcaagtt tgttaccttg gttgacaatc
    21001 cattctttat tataaaatgg ttgaagtttc tcaatattac gataagctaa atcacgttcg
    21061 gatttgtagt cttgagttga cttatattca tcttctcttc tggttaaacg atttaagcga
    21121 ttgaccacag gttcgttgat ttcgtattta tcagcagtaa gtccaaaatt tgcaattctc
    21181 ttattagctt catcttgact aatttcttta attttgtcac gagaacgttt gtatgaatgc
    21241 ttacctgaac tgacaccttt gacaacaaag ttacgctcta accagccatt tgtgaaataa
    21301 ccaccatcgt agtccaaatc ggaagaacca aagaactctt caccattttc aactctcatc
    21361 attgaaatat tatcttcaag tttaccaaaa ggaagattgc tattgataaa tccacctgtt
    21421 tcaaacaaaa ctttagtctt aatggttcct ttggtgactg atttacgaat tgaaccgtat
    21481 ttaccaattc ccatagagtc gttaccatta tctgttttag caactaaacc acctatacgg
    21541 gctctgttag caacaatatc agcctcgaca tatgcttttg caagattacc tctccaaatc
    21601 tcaccggcaa tgccagccat atattgacct ttatcaccaa cacctgtaag attaccgatg
    21661 aaggctacat ttgtcaactg accaccacta tcgattttat tgacgatacc cgcaatattg
    21721 ttattagcaa ctacattacc agttacctta acatcttcaa cagttgcatt tttcaccata
    21781 ttggcaacag gtgctattcc gtcagcccaa ggcatattga tatccacatt acctaaatta
    21841 atatttttca cagaaccatt ttcaacacgg tcaaataagg gacgggcaat gttatgaatt
    21901 gtatattgtt taccatcaac acttgataga tgtcccttaa acgtacctgg aacatattgt
    21961 ttgttaggtg ttggtacatt cgttgcattc aaatctgctc cgattttaaa tgtaccattt
    22021 ttatcagcat tcatggcatc tactaactct ttaaagttat aataaacgtc atcaactttt
    22081 ggaactggtt tttcaatata atgaacatac ttgttacgaa ccttcgttgg gtctgtatgt
    22141 tgaatcaaat cttgagcttc ggcagtgatt ttataaagtt tcttaccttc ttcagtcact
    22201 tcttcaattt tatcaactgc taaacgtgtt actttattat cacgactagt aatttttaag
    22261 tacattttct tcacatcttc atctgaaggt ttttcagtca taaaatcact aggtgtttca
    22321 gtaccatcgt catttacctt cactaaatta gtagatgcga tatttttaat ttcaactttt
    22381 ttcaaatcca agcgaagtgg tttctcttct aatgttgcag tttcttctcc cttgccacgg
    22441 tcataggtca tagtggtctc tatcttatag tccttgtaga attttaaatc ttctacctgc
    22501 ttatctaatt gctctgaagt caaatctact gttttgacaa tttcatttcc atctttaatt
    22561 gtcgcagtaa ttttattgat tgtgactcca tctgtattaa ctaaatgata agaaagagtt
    22621 gcggatcggt ttaatacatt tgtatttgtt ctatctaagg tcaaaacagg agccgttttt
    22681 tctttaggtt tttctttggt accttttaca agaattttag gcttcatttc tttcaaaata
    22741 gttactgttt caactgggtc actgattttt ttgccatgta actcttcata gctagtaaca
    22801 atttgacgtt cgccatcctc accaacttgt ctaacagaat catcgcctat aaatttgcta
    22861 ggatcagatt cttctatagt ggttttagga atagtctctg tccgaatatc ggtatgtaaa
    22921 gaaggcaact cttctctttc tgatgcaact tctgaaactg tagatattgg ttcagtatac
    22981 tctggaatgt cgctaacagg tggctcaatc aagtttccat tttcatccac tcctgttgta
    23041 cctactggct cagtatattc tgggatgtcg ttaacaggtg gttcaatcaa gtttccattt
    23101 tcatctactc ctgttgtccc tactggttca gtgtatgcta gtttctcatg aacttcaggc
    23161 tcaacaaggt ttgcacctat tggttgcgta tagtcaggct tctcatgaac ttccggttcg
    23221 cctttctctg ttacaacttt gggttgctca actggcgaaa cagttgatgc tggagaaacc
    23281 gacgaaacag ttttatcatc aagctccaag taaccaacat atctgtaacc agaaatttgc
    23341 aacacaccat cacgtccaga ctcatggatg ttagcattca aattaagtgc tgaagcagtt
    23401 gatagtgtaa ctaaacctgt cgcccctaca atcaaaaatg tagctatttt tttatttcta
    23461 ttatcttttg tgataatcac aataagactc ccgatagcta acaaacccaa tgcagtcata
    23521 atagattgag aacttcctgt gtttggtagt gcgtcttttt cataatccaa agcatatgac
    23581 tctttggatt catcaggtct accttgtttg agttgatcac gttcagtttg tgtcaaacta
    23641 ctataatcta agtaatgata agtcgatgca ccaacaactg acggtgcaaa taaaagactc
    23701 cccaagaata ccgaaccaac aatacccttt attttccgaa tggaaaattt atcttttttt
    23761 aataatgaca attctaatcc tccaccttca ctttttattt cctaatagta aacactattt
    23821 tttattctca aaaattgaac ttctaaaatc accggtttgg tcaagataag ctttaaagat
    23881 tgcttttttc agtttaagaa ctctactatt tgtctcagga tataatttgg caacttcatc
    23941 ctcagcatca aattttactg catcttcaat cattttttca agtctattaa tattatcaat
    24001 agtcactttc tgttgtcgag cccaagaacc gtttggatcg ataaaactaa ctttatttaa
    24061 ctttccaaat ttatcttctc tttctttata catatctttc ttgaaatcta tccaagaatt
    24121 atactggtta ttaaatactt ttgaaagaac aatttcatca gtaactaaac ctatttgttt
    24181 accatatgat gtaataactt ttccttgagc tttcgcttct ttttcatact gattagaaat
    24241 atatggaacc ataccgtctt tgtacccctt ggctgccaat aactcaaatg caatacgtcg
    24301 tcccattaaa tctcctggtg ttcctatttt actgctcaat gctgaataaa ttggtgagaa
    24361 tagattaatt gtatagtagc cattccgctt ataagttgct tcatctacat aacctcttct
    24421 tgttataata tcatgttcta tcaaactgtt aaatgtagtt aatttagtaa gttcttctgg
    24481 ttttaatcta cgtacaacat tcgttgcata aacagaattt ccatcaggat caggtttata
    24541 ttcattttct atttttctta ataaatcata tttttgattt gtatctaatt tagctacagc
    24601 tttaccttct agtatttcaa gcatgtatat tacatcaaac atattatgca tatacttatt
    24661 tagatcatca acacttccaa atcgttgagt tggatctgct acttgaagcc ttgttgattc
    24721 ttctgattga tcatatttta atatggaatt aatagtgact gttggatcat taggatgatc
    24781 aggagcttgt agcagtcctt tagcataaaa ctctggtcca agtccatttc gtcttccata
    24841 gcctccaaga taaatttctc tatctgagtt atgtgtcatt tcgtgtgtat aagttaccgc
    24901 accatcttta tcaagcatgc gatatgccat ataatagaat gcatcccctg tagcatatgc
    24961 tccattagaa ttatgaacaa cattatttcc cgctggaccg aagaaatgtt ttatagctgg
    25021 atgattagtt tcaaaagttg cttgatatgt atctttatct tctttttcat ctgtaccaaa
    25081 tctaaatgca tcatagacta gaacacttct atataatttt tctttatttt tatcatctag
    25141 tattctatac caataatcat agtgatctct aaatctaaca gccgcttctt tagctttttt
    25201 ctcaacatag tcatttaaat cagttcctgc tggatgttct ttacttctat atctatcata
    25261 agcaccgaaa cctatagtcg aaatgttggc tataataaac accgattttt caggtaatgt
    25321 taatagcggc aacaccatac ttggatattt ccaagatggg ctagttaatc tatcatatac
    25381 tccaattgaa tatggactac cagctattga ttgcttatca cttacctctt taatagtaga
    25441 tttttcttct acaatatatg ctttagtttg ttctttaaac cactcattat ttgttttatc
    25501 tggtacaaat gcttttctat atttctctaa tgcatcaaat aaattattag tcttataatt
    25561 tttcgctaat aaaacattat aagttataac attatttttt gctagtaagt tattatatcc
    25621 cgatttacct agttcgataa cattatctaa cgctgaacta tttgatttac cgaagaaatc
    25681 caagtggtac atgactaaat ctttcgcttt tgtatcacga tatttgaagt cgtaccaacg
    25741 ctctaagtat gttaatccta gaagtaaagc ttctttatta tttttaattt tctcgattac
    25801 ataattatct attaccttat tgttattttc agctattgca gcatctgcag taagaagttt
    25861 tgtcaaacta tctttcaaat tagtttttgt ggtattgaat tgttcttcta aatataactc
    25921 cgttaaacta acatccttag aaacatctaa tacttttcta attgcctctg atttatattc
    25981 tacactattt aatgctggta atacttcatc taaaatattt tgataattgc gaagtaatgt
    26041 attcggtgta taaattaagt ttgtaccgcc tattctatac tctgctacat ttgaaaaatc
    26101 agtttgataa tttacattaa gtgtctctga tgtattatcc gcgtaatata gtaatagttt
    26161 atttatactt gatttatttt tgttaatatc actaattact tctttatctt tcatagggac
    26221 tactgacaat aattctttat tataaagatt actacttgtc tctactaaat ttccgtactt
    26281 aacaattgtt tctctattat aaaacggtaa tagtttttca atatttttat atacttttt
//
LOCUS       DBEJAU010000029        26035 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC323 isolate 683620
            SAMN38261939-rid24807223.denovo.029, whole genome shotgun sequence.
ACCESSION   DBEJAU010000029 DBEJAU010000000
VERSION     DBEJAU010000029.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261939
            Sequence Read Archive: SRR26833919
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 26035)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 26035)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576303.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576303.1
            Genome Coverage       :: 154x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/19/2025 01:05:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,121
            CDSs (total)                      :: 2,078
            Genes (coding)                    :: 1,943
            CDSs (with protein)               :: 1,943
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 36
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 72 of 135
            Pseudo Genes (incomplete)         :: 63 of 135
            Pseudo Genes (internal stop)      :: 51 of 135
            Pseudo Genes (multiple problems)  :: 46 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..26035
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261939-rid24807223.denovo.029"
                     /strain="GPSC323"
                     /isolate="683620"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            complement(138..1808)
                     /locus_tag="ACL29Z_001261"
     CDS             complement(138..1808)
                     /locus_tag="ACL29Z_001261"
                     /EC_number="6.3.4.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019803354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004329 - formate-tetrahydrofolate ligase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="formate--tetrahydrofolate ligase"
                     /protein_id="HGR0069572.1"
                     /translation="MKTDIEIAQSIELKPIVDVVEKLGISYDDLELYGKYKAKLSFDK
                     IRAVESNPVGKLILVTAINPTPAGEGKSTLTIGLADALNKIGKKTMIAIREPSLGPVM
                     GIKGGAAGGGYAQVLPMEDINLHFTGDMHAITTANNALSALIDNHLHQGNELGIDQRR
                     ILWKRVVDLNDRALRHVTVGLGGPLNGIPREDGFDITVASEIMAILCLATDIEDLKRR
                     LANIVIGYRYDRTPVSVGDLQVEGALALILKDAIKPNLVQTIYGTPAFVHGGPFANIA
                     HGCNSVLATTTALHLADYTVTEAGFGADLGAEKFLDIKTPNLPTSPDAVVIVATLRAL
                     KMNGGVAKDALTEENVEAVRAGFANLKRHVENIRKFGIPAVVAINEFVSDTEAEIAVL
                     KELCASIDVPVELASVWADGAEGGVALAETVVKTIAENPANYKRLYDNDLSVQEKIEK
                     IVTEIYRGSKVNFEKKAQTQIAQIVQNGWDKLPICMAKTQYSFSDNPNALGAPENFEI
                     TIRELVPKLGAGFIVALTGDVMTMPGLPKRPAALNMDVESDGTVLGLF"
     gene            2038..2727
                     /gene="coaB"
                     /locus_tag="ACL29Z_001262"
     CDS             2038..2727
                     /gene="coaB"
                     /locus_tag="ACL29Z_001262"
                     /EC_number="6.3.2.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000699493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004632 - phosphopantothenate--cysteine
                     ligase activity [Evidence IEA];
                     GO_process: GO:0015937 - coenzyme A biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopantothenate--cysteine ligase"
                     /protein_id="HGR0069573.1"
                     /translation="MKILVTSGGTSEAIDSVRSITNHSTGHLGKIITETLLFAGHEVC
                     LITTKRALKPEPHPNLSIREITNTKDLLIEMQERVQDYQVLIHSMAVSDYTPVYMTGL
                     EEVQASSNLKEFLSKQNHQAKISSTDEVQVLFLKKTPKIISLVKEWNPTIHLIGFKLL
                     VDVTEDHLVDIARKSLIKNQADLIIANDLTQISAGQHRAIFVEKNQLQTVQTKEEIAE
                     LLLEKIQAYHS"
     gene            2739..3290
                     /gene="coaC"
                     /locus_tag="ACL29Z_001263"
     CDS             2739..3290
                     /gene="coaC"
                     /locus_tag="ACL29Z_001263"
                     /EC_number="4.1.1.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001284124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004633 - phosphopantothenoylcysteine
                     decarboxylase activity [Evidence IEA];
                     GO_process: GO:0015937 - coenzyme A biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopantothenoylcysteine decarboxylase"
                     /protein_id="HGR0069574.1"
                     /translation="MANILLAVTGSIASYKSADLVSSLKKQGHQVTVLMTQAATEFIQ
                     PLTLQVLSQNPVHLDVMKEPYPDQVNHIELGKKADLFIVVPATANTIAKLAHGFADNM
                     VTSTALALPSHIPKLIAPAMNTKMYDHPVTQNNLKTLETYGYQLIAPKESLLACGDHG
                     RGALADLTIILERIKETIDEKTL"
     gene            3274..3837
                     /locus_tag="ACL29Z_001264"
     CDS             3274..3837
                     /locus_tag="ACL29Z_001264"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000747407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HGR0069575.1"
                     /translation="MKKRSNIAPIAIFFATMLVIHFLSSLIFNLFPFPIKPTIVHIPV
                     IIASIIYGPRVGVTLGFLMGLLSLTVNTITILPTSYLFSPFVPNGNIYSAIIAIVPRI
                     LIGLTPYLVYKLMKNKTGLILAGALGSLTNTIFVLGGIFFLFGNVYNGNIQLLLATVI
                     STNSIAELVISAILTLAIVPRLQTLKK"
     gene            4119..4646
                     /locus_tag="ACL29Z_001265"
     CDS             4119..4646
                     /locus_tag="ACL29Z_001265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HGR0069576.1"
                     /translation="MNTRKKTQFMTMTALLTAIAILIPIVMPFKIVIPPASYTLGSHI
                     AIFIAMFLSPLMAIFVILASSFGFLMAGYPMVIVFRAFSHIFFGTLGALYLQKFPDTL
                     DKPKASWIFNFVLALVHALAEVLACVVFYATSGTNVENMFYVLFVLVGFGTIIHSMVD
                     YTLALAVYKVLRKRR"
     gene            4658..5173
                     /locus_tag="ACL29Z_001266"
     CDS             4658..5173
                     /locus_tag="ACL29Z_001266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription repressor NadR"
                     /protein_id="HGR0069577.1"
                     /translation="MTKDRKQALLQLLKEAPKALNGQSLAEHFHVTRQVIVQDIAILR
                     ADGAPILSTNRGYVYKQIDTNPYVHKLFKVKHEVEEIGQELLAIVDNGGRVQNTLIDH
                     PVYGEIETLLKLSCRRDVQHFLEQVEHSDFKPLSELTDGVHYHLVEAETQQDLHYIEE
                     ALDQLGYLVKD"
     gene            complement(5170..5637)
                     /locus_tag="ACL29Z_001267"
     CDS             complement(5170..5637)
                     /locus_tag="ACL29Z_001267"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000085289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="8-oxo-dGTP diphosphatase"
                     /protein_id="HGR0069578.1"
                     /translation="MSRAQLTILTNICLIEDLEAQRVVMQYRAPETNRWSGYAFPGGH
                     VENGESFAESVIREIYEETGLTIQNPQLVGIKNWPLDTGGRYIVVCYKATEFSGTLRS
                     SDEGEVSWVQKDQIPNLDLAYDMLPLMEMMEASDKSEFFYPRRTEDDWEKKIF"
     gene            complement(5710..6198)
                     /locus_tag="ACL29Z_001268"
     CDS             complement(5710..6198)
                     /locus_tag="ACL29Z_001268"
                     /EC_number="2.3.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0016746 - acyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HGR0069579.1"
                     /translation="MTVIIKSMETPEEIEGKSLVHWQTWREAYDDLLPAEFQETMTLE
                     RCRFFSQKYPENTLIAIGDLKVVGFISYGNFRDETIQAGEIIALYVLKDYYGKGIAQK
                     LMKTALTALNRFSEIFLWVLKDNKRAIAFYQKMGFTFDGQEKMLELGKPIKEKRMVFY
                     SK"
     gene            complement(6164..6727)
                     /locus_tag="ACL29Z_001269"
     CDS             complement(6164..6727)
                     /locus_tag="ACL29Z_001269"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000639844.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family protein"
                     /protein_id="HGR0069580.1"
                     /translation="MIYLRKLKKEDLMSLWEMAYSQLNPVWKQYDAPYYDDYQYFSNF
                     KEFELQKSESILSNSNRLGIFVDDKLVGTVSRYWVCKETRWMELGIGIYDKKFWNTGI
                     GKVAMLQWIDRTFQDYLELEHLGLTTWSGNLGMMKLAEKLRMKKEAHIPKVRYYQGKY
                     FDSIKYGILREDWEKINDGYYQINGNS"
     gene            complement(6737..8725)
                     /gene="uvrB"
                     /locus_tag="ACL29Z_001270"
     CDS             complement(6737..8725)
                     /gene="uvrB"
                     /locus_tag="ACL29Z_001270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009380 - excinuclease repair complex
                     [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_process: GO:0006289 - nucleotide-excision repair
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrB"
                     /protein_id="HGR0069581.1"
                     /translation="MINHITDNQFKLVSKYQPSGDQPQAIEQLVDNIEGGEKAQILMG
                     ATGTGKTYTMSQVISKVNKPTLVIAHNKTLAGQLYGEFKEFFPENAVEYFVSYYDYYQ
                     PEAYVPSSDTYIEKDSSVNDEIDKLRHSATSALLERNDVIVVASVSCIYGLGSPKEYA
                     DSVVSLRPGLEISRDKLLNDLVDIQFERNDIDFQRGRFRVRGDVVEIFPASRDEHAFR
                     VEFFGDEIDRIREVEALTGQVLGEVDHLAIFPATHFVTNDDHMEVAVAKIQAELEEQL
                     AVFEKEGKLLEAQRLKQRTEYDIEMLREMGYTNGVENYSRHMDGRSEGEPPYTLLDFF
                     PDDFLIMIDESHMTMGQIKGMYNGDRSRKEMLVNYGFRLPSALDNRPLRREEFESHVH
                     QIVYVSATPGDYENEQTETVIEQIIRPTGLLDPEVEVRPTMGQIDDLLGEINARVEKN
                     ERTFITTLTKKMAEDLTDYFKEMGIKVKYMHSDIKTLERTEIIRDLRLGVFDVLVGIN
                     LLREGIDVPEVSLVAILDADKEGFLRNERGLIQTIGRAARNSEGHVIMYADTVTQSMQ
                     RAIDETARRRKIQMAYNEEHGIVPQTIKKEIRDLIAVTKAVAKEEDKEVDINSLNKQE
                     RKELVKKLEKQMQEAVEVLDFELAAQIRDMMLEVKALD"
     gene            complement(8802..9755)
                     /locus_tag="ACL29Z_001271"
     CDS             complement(8802..9755)
                     /locus_tag="ACL29Z_001271"
                     /EC_number="3.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000792120.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0070007 - glutamic-type endopeptidase
                     activity [Evidence IEA];
                     GO_process: GO:0071586 - CAAX-box protein processing
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane glutamic
                     endopeptidase"
                     /protein_id="HGR0069582.1"
                     /translation="MKNKRIFKDFQASKMNLNIYTSPLLAFVFVFIGEFVAYTLYGIS
                     LLALIGLARNFGEAGQNLASYLQTLHQSLTDKTSDFRLILGLLAFGFILNTVFRWTRK
                     VEKRPIRTLGFYRENFLSNLLKGFSLGLALFLLTLLGLVVLGQYRLESIHLNPYSLAF
                     VVFTIPFWILQGTAEEVVARAWLLPQLASRTNLKLAILISSLFFTLLHMGNSGLTPLS
                     LVNLFLFGVAMALYLLKTDTVWGVAGIHGAWNFAQGNLFGILVSGQPSGTSLMTFLPQ
                     GNQDWLSGGSFGIEGSIMTSLVLLLLIVYLANKLKKENERM"
     gene            9928..12093
                     /locus_tag="ACL29Z_001272"
     CDS             9928..12093
                     /locus_tag="ACL29Z_001272"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000726259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding
                     protein/permease"
                     /protein_id="HGR0069583.1"
                     /translation="MKKKFLAFLLILFPTFSLGIAKAETIKIVSDTAYAPFEFKDSDQ
                     TYKGIDVDIINKVAEIKGWNIQMSYPGFDAAVNAVQAGQADAIMAGMTKTKEREKVFT
                     MSDTYYDTKVVIATTKSHKISKYDQLTGKTVGVKNGTAAQRFLETIKDKYGFTIKTFD
                     TGDLMNNSLSAGAIDAMMDDKPVIEYAINQGQDLHIEMDGEAVGSFAFGVKKGSKYEH
                     LVTEFNQALAEMKKDGSLDKIIKKWTASSSSAVPTTTTLSGLKAIPVKAKYIIASDSS
                     FAPFVFQNSSNQYTGIDMELIKAIAKDQGFEIEITNPGFDAAISAVQAGQADGIIAGM
                     SVTDARKATFDFSESYYTANTILGVKESSNIASYEDLKGKTVGVKNGTASQTFLTENQ
                     SKYGYKIKTFADGSSMYDSLNTGAIDAVMDDEPVLKYSISQGQKLKTPISGTPIGETA
                     FAVKKGANPELIEMFNNGLANLKANGEFQKILDKYLASESSTASTSTVDETTLWGLLQ
                     NNYKQLLSGLGITLALALISFAIAIVIGIIFGMFSVSPYKSLRVISEIFVDVIRGIPL
                     MILAAFIFWGIPNFIESITGQQSPINDFVAGTIALSLNAAAYIAEIVRGGIQAVPVGQ
                     MEASRSLGISYGKTMRKIILPQATKLMLPNFVNQFVIALKDTTIVSAIGLVELFQTGK
                     IIIARNYQSFKMYAILAIFYLVIITLLTRLAKRLEKRIS"
     gene            12093..12833
                     /locus_tag="ACL29Z_001273"
     CDS             12093..12833
                     /locus_tag="ACL29Z_001273"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HGR0069584.1"
                     /translation="MAKLKIDVNDLHKHYGKNEVLKGITTKFYEGDVVCIIGPSGSGK
                     STFLRSLNLLEEVTSGHITVNGYDLTEKTTNVDHVRENIGMVFQHFNLFPHMSVLDNI
                     TFAPIEHKLMIKEEAEKLGMELLEKVGLADKANANPDSLSGGQKQRVAIARGLAMNPD
                     IMLFDEPTSALDPEMVGDVLNVMKELAEQGMTMIIVTHEMGFARQVANRVIFTADGEF
                     LEDGTPDQIFDNPQHPRLKEFLDKVLNV"
     gene            12982..14469
                     /gene="zwf"
                     /locus_tag="ACL29Z_001274"
     CDS             12982..14469
                     /gene="zwf"
                     /locus_tag="ACL29Z_001274"
                     /EC_number="1.1.1.49"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000096131.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004345 - glucose-6-phosphate
                     dehydrogenase activity [Evidence IEA];
                     GO_function: GO:0016614 - oxidoreductase activity, acting
                     on CH-OH group of donors [Evidence IEA];
                     GO_function: GO:0050661 - NADP binding [Evidence IEA];
                     GO_process: GO:0006006 - glucose metabolic process
                     [Evidence IEA];
                     GO_process: GO:0006098 - pentose-phosphate shunt [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-6-phosphate dehydrogenase"
                     /protein_id="HGR0069585.1"
                     /translation="MSSKVIVTIFGASGDLAKRKLYPSLFRLYKSGNLSKHFAVIGTA
                     RRPWSKEYFESVVVESILDLADSTEQAQEFASHFYYQSHDVNDSEHYIALRQLQAELN
                     EKYQAEHNKLFFLSMAPQFFGTIAKHLKSENIVDGKGFERLIVEKPFGTDYATASKLN
                     DELLATFDEEQIFRIDHYLGKEMIQSIFAVRFANLIFENVWNKDFIDNVQITFAERLG
                     VEERGGYYDQSGALRDMVQNHTLQLLSLLAMDKPASFTKDEIRAEKIKVFKNLYHPTD
                     EELKEHFIRGQYRSGKIDGMKYISYRSEPNVNPESTTETFTSGAFFVDSDRFRGVPFF
                     FRTGKRLTEKGTHVNIVFKQMDSIFGEPLAPNILTIYIQPTEGFSLSLNGKQVGEEFN
                     LAPNSLDYRTDATATGASPEPYEKLIYDVLNNNSTNFSHWDEVGASWKLIDRIEKLWA
                     ENGAPLHDYKAGSMGPQASFDLLEKFGAKWTWQPDIAYRQDGRLE"
     gene            complement(14515..15804)
                     /gene="ftsY"
                     /locus_tag="ACL29Z_001275"
     CDS             complement(14515..15804)
                     /gene="ftsY"
                     /locus_tag="ACL29Z_001275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000522312.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005047 - signal recognition particle
                     binding [Evidence IEA];
                     GO_process: GO:0006614 - SRP-dependent cotranslational
                     protein targeting to membrane [Evidence IEA];
                     GO_process: GO:0009306 - protein secretion [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="signal recognition particle-docking protein
                     FtsY"
                     /protein_id="HGR0069586.1"
                     /translation="MGLFDRLFGKKEEPKIEEVVKEALENLDLSEYVDPTFTEVEEVS
                     QEEAEVEIIEQAVFQEEEIQDTVEESLDSEPVVGVSQEEVEEFPHSEELPEEEKLEHE
                     GTVEESNSEVLEPEAPQTEETVQEKYDRSLKKTRTGFGARLNAFFANFRSVDEEFFEE
                     LEELLIMSDVGVQVASNLTEELRYEAKLENAKKPDVLRRVIIEKLVELYEKDGSYDES
                     IHFQDNLTVMLFVGVNGVGKTTSIGKLAHRYKQAGKKVMLVAADTFRAGAVAQLAEWG
                     RRVDVPVVTGPEKADPASVVFDGMERAVAEGIDILMIDTAGRLQNKDNLMAELEKIGR
                     IIKRVVPEAPHETFLALDASTGQNALVQAKEFSKITPLTGIVLTKIDGTARGGVVLAI
                     REELNIPVKLIGFGEKIDDIGEFNSENFMKGLLEGLI"
     gene            complement(15808..16626)
                     /locus_tag="ACL29Z_001276"
     CDS             complement(15808..16626)
                     /locus_tag="ACL29Z_001276"
                     /EC_number="3.1.3.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016465979.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HGR0069587.1"
                     /translation="MADIKLIALDLDGTLLTTDKRLTDRTKETLKAARDRGIKVVLTT
                     GRPLKAMDFFLHELGTDGQEDEYTITFNGGLVQKNTGEILDKTVFSYDDVARLYEETE
                     KLSLPLDAISEGTVYQIQSDQESLYAKFNPALTFVPVDFEDLSNQMTYNKCVTAFAQE
                     PLDAAIQKISPELFDQYEIFKSREMLLEWSPKNVHKATGLAKLISHLGIDQSQVMACG
                     DEANDLSMIEWAGLGVAMQNAVPEVKAVANVVTPMTNDEEAVAWAIEEYVLKEN"
     gene            complement(16626..17420)
                     /locus_tag="ACL29Z_001277"
     CDS             complement(16626..17420)
                     /locus_tag="ACL29Z_001277"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000153012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HGR0069588.1"
                     /translation="MTIKLVATDMDGTFLDGNGRFDMDRLKSLLASYKEKGIYFAVAS
                     GRGFLSLEKLFADVRDDIIFIAENGSLVEYQGQDLYEATMSRDFYLATFEKLKTSPYV
                     DINKLLLTGKKGSYVLDTVDETYLKVSQHYNENIQKVASLEDITDDIFKFTTNFTEGT
                     LEAGEAWVNEHVSGVKAMTTGFESIDIVLDYVDKGVAIVELAKKLGITMDQVMAFGDN
                     LNDLHMMQVVGHPVAPENARPEILELAETVIGHHKDQSVIAYMEGL"
     gene            complement(17417..20956)
                     /gene="smc"
                     /locus_tag="ACL29Z_001278"
     CDS             complement(17417..20956)
                     /gene="smc"
                     /locus_tag="ACL29Z_001278"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000280891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0007059 - chromosome segregation [Evidence
                     IEA];
                     GO_process: GO:0030261 - chromosome condensation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="chromosome segregation protein SMC"
                     /protein_id="HGR0069589.1"
                     /translation="MYLKEIEIQGFKSFADKTKVVFDQGVTAVVGPNGSGKSNITESL
                     RWALGESSVKSLRGGKMPDVIFAGTESRKPLNYASVVVTLDNHDGFIKDAGQEIRVER
                     HIYRSGDSEYKIDGKKVRLRDIHDLFLDTGLGRDSFSIISQGKVEEIFNSKPEERRAI
                     FEEAAGVLKYKTRRKETESKLQQTQDNLDRLEDIIYELDNQIKPLEKQAENARKFLDL
                     EGQRKAIYLDVLVAQIKENKAELESTEEELAQVQELLMSYYQKREKLEEENQTLKKQR
                     QDLQAEMAKDQGSLMDLTSLISDLERKLALSKLESEQVALNQQEAQARLAVLEDKRNS
                     LSQEKSDKESSLVLLEENLVQNNQKLNRLEAELLAFSDDPDQMIELLRERFVALLQEE
                     ADVSNQLTRIENELENSRQLSQKQADQLEKLKEQLAIAKEKASQQKEELETAKEQVQK
                     LLADYQAIAKEQEEQKTSYQAQQSQLFDRLDNLKNKQARAQSLENILRNHSNFYAGVK
                     SVLQEKDRLGGIIGAVSEHLTFDMHYQTALEIALGASSQHIIVEDEESATKAIDFLKR
                     NRAGRATFLPLTTIKARTISSQNQDAIAVSPGFLGMADELVTFDTRLEAIFKNLLATT
                     AIFDTVEHARAAARQVRYQVRMVTLDGTELRTGGSYAGGANRQNNSIFIKPELEQLQK
                     EIAEEEASLGSEEATLKTLQDQMARLTESLEAIKSQGEQARIQEQGLFLAYQQTSQQV
                     EELETLWKLQEKEKDRLSEGDWQADKEKCQERLAAIASDKQNLEAEIEEIKSNKNAIQ
                     ERYQNLQEELAQARLLKTELQGQKRYEVTDIERLGKELDNLDIEQEEIQRLLQEKVDN
                     LEKVDTDLLSQQADEAKTQKTNLQQGLIRKQFELDDIEGQLDDIASHLDQARQQNEEW
                     IRKQTRAEAKKEKVSERLRHLQSQLTDQYQISYTEALEKAHELENLNLAEQEVKDLEK
                     AIRSLGPVNLDAIEQYEEVHNRLDFLNSQRDDILSAKNLLLETITEMNDEVKERFKST
                     FEAIRESFKVTFKQMFGGGQADLILTEGDLLTAGVEISVQPPGKKIQSLSLMSGGEKA
                     LSALALLFSIIRVKTIPFVILDEVEAALDEANVKRFGDYLNRFDKDSQFIVVTHRKGT
                     MAAADSIYGVTMQESGVSKIVSVKLKDLESIEG"
     gene            complement(20947..21645)
                     /gene="rnc"
                     /locus_tag="ACL29Z_001279"
     CDS             complement(20947..21645)
                     /gene="rnc"
                     /locus_tag="ACL29Z_001279"
                     /EC_number="3.1.26.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0004525 - ribonuclease III activity
                     [Evidence IEA];
                     GO_process: GO:0006364 - rRNA processing [Evidence IEA];
                     GO_process: GO:0006396 - RNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease III"
                     /protein_id="HGR0069590.1"
                     /translation="MKELQTVLKNHFAIEFADKNLLETAFTHTSYANEHRLLKISHNE
                     RLEFLGDAVLQLLISEYLYKKYPKKPEGDLSKLRAMIVREESLAGFARDCQFNQFIKL
                     GKGEEKSGGRNRDTILGDAFEAFLGALLLDKDVAKVKEFIYQVIIPKVEAGEFEMITD
                     YKTHLQELLQVNGDVAIRYQVISETGPAHDKVFDVEVLVEGKSIGQGQGRSKKLAEQE
                     AAKNAVEKGLDSCI"
     gene            complement(21828..21899)
                     /locus_tag="ACL29Z_001280"
     tRNA            complement(21828..21899)
                     /locus_tag="ACL29Z_001280"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(21864..21866),aa:Arg,seq:ccg)
     gene            complement(21963..22949)
                     /locus_tag="ACL29Z_001281"
     CDS             complement(21963..22949)
                     /locus_tag="ACL29Z_001281"
                     /EC_number="1.7.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007516839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902560 - GMP reductase complex [Evidence
                     IEA];
                     GO_function: GO:0003920 - GMP reductase activity [Evidence
                     IEA];
                     GO_process: GO:0006163 - purine nucleotide metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GMP reductase"
                     /protein_id="HGR0069591.1"
                     /translation="MLNEFPIFDYEDIQLIPNKCVIKSRAEADTSVTLGNHTFKLPVV
                     PANMQTILDENVAEQLAKGGYFYIMHRFDEAGRIPFIKRMHDQGLIASISVGVKDYEY
                     DFVSQLKADAPEYITIDIAHGHADSVISMIQHIKKELPDTFVIAGNVGTPEAVRELEN
                     AGADATKVGIGPGKVCITKVKTGFGTGGWQLAALRWCAKAARKPIIADGGIRTHGDIA
                     KSIRFGASMIMIGSLFAGHIESPGKTIEVDGEQFKEYYGSASQYQKGAYKNVEGKRIL
                     LPAKGHLQDTLTEMEQDLQSAISYAGGRQVADLKHVDYVIVKNSIWNGDASH"
     gene            complement(23124..24440)
                     /locus_tag="ACL29Z_001282"
     CDS             complement(23124..24440)
                     /locus_tag="ACL29Z_001282"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001223073.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="McrC family protein"
                     /protein_id="HGR0069592.1"
                     /translation="MRITDNQHKIIKEKFVEEYPKLSNLLLDRTLESLSQDERIFIFP
                     NDLTHTPDLDKDQKIFETVNQKIKTGNVIGFLGYGQERLTISSRFSDESNDHFLHYLL
                     NKVLHINLTSLDVALSREERLYQLLMYLFPKYLQAAIRKGLYKEYHRFSHNDSHVKGV
                     IDVRSHLKKNLPFTGNIAYATREFTYDNPLMQLVRHTIEYIKNQKSIGQGVLDNLSTS
                     RENVSEIVRVTPSYKLADRAKIIRGNQSKPIRHAYFHEYRNLQELCLMILNQEKHGLG
                     YQDQKIYGILFDVAWLWEEYVYTLLPKGFVHPRNKDKTDGISVFSVGKRKVYPDFYDR
                     ERKIVLDAKYKKLELTEKGINREDLFQLISYSYILKAEKAGLIFPSMEQSVNSEIGKV
                     AGYGAQLKKWSIRIPQNASFYSAFCKMMENSEENFKAIIDEEVGRK"
     gene            complement(24427..>26035)
                     /locus_tag="ACL29Z_001283"
     CDS             complement(24427..>26035)
                     /locus_tag="ACL29Z_001283"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001042398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="McrB family protein"
                     /protein_id="HGR0069593.1"
                     /translation="NEISELDQRFSKLKSDLYEIIKEGIRFNFENPIFDMKRSTNEFI
                     GRSAMVTKLLCIYTEGDPFFGVNINSQKEFWNHFVSQTNQGGPYLQNHKIIELVSKTY
                     PELEPSKLGTILFEYSKLFMENKEDNSTMDSSNNFSHQLTQSLLKSPNLILRGAPGTG
                     KTYLAKEIAKELTDGNEDQIGFVQFHPSYDYTDFVEGLRPVSNGDGAIEFRLQDGIFK
                     DFCQKAKETQLIGGQDNFDEAWDSYLEYINVAEEKEYITKTSYLSVNSRQNLSVNYDS
                     GVPGWSLPSKYVYELYKDKNYNKQEYYKSGGKTVLETLRKRFGLKDYVSPTEIDTDKK
                     FVFIIDEINRGEISKIFGELFFSIDPGYRGEKGSVSTQYANLHETDEKFYIPENVYII
                     GTMNDIDRSVDTFDFAMRRRFRFVEVTAEGQVGMLDKELNIHAEEAKIRLRNLNAAIE
                     NVQELNSHYHIGPSYFLKLKDVDFDYELLWSDYIKPLLEDYLRGSYDEVETLETLKKA
                     FELTNNEQKDQAVADDNEGDENDDADY"
BASE COUNT         7627 a         5788 c         4652 g         7968 t
ORIGIN      
        1 acctacggca aggtgaagct gacgtagttt gaaaagattt tcgaagagta taaatcttat
       61 tgatgaactg cttgcagtct gagaaaaaat gagcttggat attatttcca aactcactta
      121 aagtcaattt caatccacta gaacaagcct agcacagttc catcgctttc aacatccatg
      181 ttgagagctg ctggacgttt tggaagacct ggcatggtca taacatcacc agttaaggca
      241 acgatgaagc ctgcacctaa ttttggtacc aattcacgaa tggtaatttc aaagttttct
      301 ggtgctccaa gcgcatttgg attgtctgag aaactgtatt gagttttagc catacaaatt
      361 ggcaatttgt cccaaccgtt ttgaacgatt tgagcaattt gtgtttgagc tttcttctca
      421 aagttcactt tgctaccacg atagatttca gtgacaattt tttcaatctt ttcttggaca
      481 gaaaggtcat tatcgtacaa acgtttatag ttagctggat tttcagcaat tgtcttaaca
      541 actgtttcgg caagtgctac tccaccttct gctccatcag cccagacact agccaattca
      601 actggtacat cgattgaggc acagagttct tttaagactg caatttcagc ttctgtatca
      661 gatacaaatt cgttaatagc tacaactgct ggaataccga acttacggat attttcaacg
      721 tggcgtttca agttagcaaa acctgcacga actgcctcta cattttcttc agtcagagcg
      781 tctttagcca caccaccatt catcttaagg gcacgaaggg ttgcgacaat aacaactgca
      841 tctggagatg ttggcaagtt tggtgtcttg atatcaagga atttctcagc accaagatcc
      901 gcaccaaaac cagcttcagt aacagtgtaa tcagccaagt gaagggctgt tgtcgtcgcc
      961 aaaacagagt tacagccatg agcgatattg gcaaatggac caccgtgtac aaaggcaggt
     1021 gtaccgtaaa ttgtctgaac caagtttggc ttaatagcat ccttcaaaat caaagccaag
     1081 gcaccctcaa cctgcaaatc acctacagaa acaggcgtac ggtcatagcg ataaccaata
     1141 acgatattcg ccaaacgacg tttcaagtcc tcgatgtccg ttgccaagca aagaattgcc
     1201 atgatttctg aagcaactgt aatatcaaaa ccatcctcac gtggaatacc gtttagagga
     1261 ccaccaagac caacagtcac atggcggagc gcacggtcgt tcaagtccac aacgcgtttc
     1321 cagaggatac gacgttgatc aattcccagc tcattccctt ggtgcaagtg gttgtcaatc
     1381 aaggcagaaa gggcattgtt ggcagttgta atagcatgca tatctccagt aaagtggagg
     1441 ttgatgtctt ccattggcag aacttgtgca tacccaccac cagcagcacc acccttgatc
     1501 cccatgactg gaccaagaga cggttcgcgg atagcaatca tggttttctt gccaatcttg
     1561 ttcaaggcat ccgcaagacc aatggtaagc gtcgactttc cttcacctgc aggtgttggg
     1621 ttgatggcag taaccaagat caatttaccg actggattgc tctcaactgc acgaatttta
     1681 tcaaagctga gtttagcctt gtactttccg tacaactcca aatcgtcgta agaaatacca
     1741 agtttctcta caacatcaac aattggcttc aactcaatac tctgtgcgat ttcaatatct
     1801 gttttcattc aaaattcctc taacctctta tatgataatt cattatatca caaaacaaga
     1861 tttttaacat cctaaaactc tctaaacgtt cgtaaatatc tctgttttta agacttttag
     1921 agtcctttct taaattttat atggctttat agtttgaaac tataataaat tttcgttttt
     1981 accaaaaatt tatcactttc attttactta ccgcttattt ttgtgtacaa tagtgctatg
     2041 aaaattttag ttacatcggg cggtaccagt gaagctatcg atagcgtccg ctctatcact
     2101 aaccattcta caggtcactt ggggaaaatt atcacagaga ctttgctttt tgcagggcat
     2161 gaagtttgtt taattacgac aaaacgagct ctgaagccag agcctcatcc taacctaagt
     2221 attcgagaaa ttaccaatac caaggacctt ctaatagaaa tgcaagaacg tgttcaggat
     2281 tatcaggtct tgatccactc aatggctgtt tctgactaca ctcctgttta tatgacaggg
     2341 cttgaggaag ttcaggctag ctccaatcta aaagaatttt taagcaagca gaatcatcag
     2401 gccaagattt cttcaactga tgaggttcag gttttgttcc ttaaaaagac acccaaaatc
     2461 atatccctag tcaaggaatg gaatcctact attcatctga ttggtttcaa actgctggtt
     2521 gatgttaccg aagatcatct ggttgacatt gcacgaaaaa gtcttatcaa gaatcaagca
     2581 gatttaatca tcgcgaatga cctgactcaa atttcagcag gtcagcaccg agctatattt
     2641 gttgagaaaa atcagcttca aacagtccag actaaagaag aaattgcaga actcctcctt
     2701 gaaaaaattc aagcctatca ttcttagaaa ggaaaactat ggcaaacatt ctcttggctg
     2761 taacgggttc aatcgcctct tataagtcgg cagatttagt cagttctcta aaaaaacaag
     2821 gccatcaagt cactgtctta atgactcagg ctgctacaga gtttatccaa cctttgacac
     2881 tacaggtact ctcacagaat cctgtccact tggatgtcat gaaagaaccc tatcctgatc
     2941 aggtcaatca tatcgaactt ggaaaaaaag cagatttatt tatcgtggta cctgcaactg
     3001 ctaacactat tgcaaaacta gctcacggat ttgcggacaa catggtaacc agtacagctc
     3061 tagccctacc aagtcatatt cccaaactaa tagctcctgc tatgaataca aaaatgtatg
     3121 accatccagt aactcagaat aatctgaaaa cattagaaac ctacggctat cagctgattg
     3181 ctcctaagga atccctacta gcttgtggag accacggacg aggagcttta gctgacctca
     3241 caattatttt agaaagaata aaggaaacta tcgatgaaaa aacgctctaa tattgcaccc
     3301 attgctatct tttttgctac catgctcgtg atacactttc tgagctcact tatctttaac
     3361 ctttttccat ttccaatcaa accgaccatt gttcatattc ctgtcattat tgccagcatt
     3421 atttatggtc cacgagttgg ggttacactt ggatttttga tgggattact tagcttgacg
     3481 gttaacacga ttacgattct accgacaagc tacctcttct ctcccttcgt accaaacgga
     3541 aacatctact cagctatcat tgccattgtc ccacgtattt tgattggttt aactccttac
     3601 ttagtctata aactgatgaa aaacaagact ggtctgattt tagctggggc tcttggttcc
     3661 ttgacaaata ctatctttgt ccttggagga atcttcttcc tatttggaaa tgtttataat
     3721 ggaaatatcc aacttcttct ggcaaccgtt atctcaacaa attcaattgc tgaattggtc
     3781 atttctgcaa ttctaaccct agccattgtt ccacgactac aaaccttgaa aaaataaaaa
     3841 caatctccgc tttcaaacct gaaggtggag attttgctct atacagtttc tttttaatga
     3901 aatctttact atagtaaaac gaaataagaa caggataaat cgatcaggac agccaaatcg
     3961 atttctaaca atgttttaga agtagaggtg gactattcta gtttcaatct actataactt
     4021 ttaactaaaa aatgatctat aaacccaagt aaattcttgc tttattgtct ggtttattgt
     4081 accatactag tgtatataca gttaaaaagg agattcttat gaacacacgg aaaaagacac
     4141 aatttatgac aatgacagcc ctcttaacgg ctattgcgat tttgattcca attgttatgc
     4201 cctttaagat tgtcattcct cctgcttctt acactttggg gagccacatc gctattttta
     4261 tcgccatgtt cttgtcaccc ttgatggcaa tttttgtcat cctagcctct agttttggat
     4321 ttttgatggc tggctatccc atggttatag tatttcgagc tttttcccat atcttttttg
     4381 ggactttggg ggctctttac ctacaaaaat tccccgatac cttagataaa ccaaaagcct
     4441 cctggatttt caactttgtg ttagcgcttg tccatgccct tgctgaagta ttggcctgtg
     4501 tcgtttttta cgcaacttct ggtaccaatg tagaaaatat gttttatgtt ctatttgtgc
     4561 tagttggatt tggcacaatt atccatagta tggtagacta tacattagca ctagctgtct
     4621 ataaagtgct tcgaaaacgc cgttaaaagg aaaagctatg acaaaagatc gcaaacaagc
     4681 tctgctccaa ctcttgaaag aagctcctaa agcccttaat ggccaaagtt tggcggaaca
     4741 ttttcatgtc acacgtcagg tcattgtgca ggacattgca attttgagag ccgatggcgc
     4801 tcctatccta tccaccaatc gtggctacgt ctataagcaa attgatacca atccttatgt
     4861 ccataaactt ttcaaggtga aacatgaagt tgaagaaatc ggtcaagaac tccttgctat
     4921 cgttgataat ggtggacgtg ttcaaaatac cttgattgac catcccgttt atggagaaat
     4981 cgaaaccttg ctgaaactgt cttgtcgccg agacgtgcaa cattttctag aacaagtcga
     5041 gcattctgat tttaaacctt tatctgaatt gacagatggt gtccattacc acctagtcga
     5101 agccgaaaca caacaagacc tccactatat cgaggaggcc ttggatcagc taggttattt
     5161 agtaaaggat tagaaaattt tcttttccca atcgtcttct gtacggcgag ggtagaaaaa
     5221 ttcagatttg tccgatgctt ccatcatctc catcaagggt agcatatcat aggccagatc
     5281 caaatttgga atctggtctt tttgcaccca agaaacttct ccttcatctg aagagcgaag
     5341 ggtaccagag aactcagttg ccttataaca aacgacaata tagcgcccac ctgtatctag
     5401 tggccaattt ttaatgccga caagttgagg attttggata gtcaaccctg tttcttcata
     5461 gatttcacga atgacagact ctgcgaaaga ttcgccattt tctacatggc ctcctggaaa
     5521 ggcataaccg gaccagcgat tagtttcagg agcgcgatac tgcatcacca cgcgctgagc
     5581 ttcgagatct tcaatcagac aaatatttgt taaaatcgtt aattgtgctc gagacataaa
     5641 tttactcact ttctaattta ttaaattttt agacttggta ccagtaccat tagcttctac
     5701 tttttaaaat tatttagaat agaataccat ccgtttttcc tttatgggct ttccaagttc
     5761 aagcattttt tcttgaccat caaaagtaaa acccattttt tgatagaaag caatggctcg
     5821 cttgttatct ttcaataccc ataagaaaat ttcagaaaaa cgattcagag cagtcaaagc
     5881 tgttttcatt aacttttgtg ctatgccttt tccataatag tcttttaaaa catataaagc
     5941 aataatttca ccagcttgaa tagtctcatc acgaaagtta ccataactga taaaaccaac
     6001 taccttcaga tcacctatcg caatcaatgt attttctgga tacttttgac taaagaatcg
     6061 acatctttct aatgtcattg tctcctgaaa ttctgcaggc aaaaggtcat cataagcctc
     6121 tctccacgtt tgccagtgaa cgagggattt accttctatc tcttcaggag tttccattga
     6181 tttgataata accgtcattt attttctccc agtcttctct caaaatacca tatttaatac
     6241 tatcaaaata tttaccttga taataacgaa cttttggaat atgagcttct tttttcattc
     6301 ttaatttttc agcaagtttc atcataccaa gatttcctga ccaagttgtc aaacccagat
     6361 gctccaactc caagtaatcc tgaaacgtcc tatctatcca ctgcaacata gcaactttcc
     6421 caataccagt gttccagaat tttttatcat aaataccaat tcccaattcc atccatcttg
     6481 tttctttaca tacccaataa cgcgaaacag tcccaactag tttatcatca acaaaaatac
     6541 caaggcgatt tgagttgctt aaaatggatt ctgatttttg tagttcgaat tctttaaaat
     6601 ttgaaaaata ctgataatca tcataatagg gagcatcata ctgtttccaa actggattaa
     6661 gctgtgaata agccatttcc cataaagaca tcaaatcttc tttctttaac tttcttaaat
     6721 aaatcatact attcccctaa tccaaggcct tgacttccaa catcatatca cggatctgag
     6781 ccgccagttc aaagtcaagc acttcgacgg cttcttgcat ttgtttttct agtttcttga
     6841 cgagttcttt gcgctcttgt ttgttgaggc tattgatgtc gacttccttg tcctcttcct
     6901 tagcaactgc cttggtcacg gcaatcaggt cacggatttc tttcttgatt gtctgtggta
     6961 cgataccatg ctcttcatta taggccatct gaattttccg acggcgggca gtttcatcga
     7021 tagcacgttg catagactgg gtaaccgtat ctgcatacat gatgacatga ccttcactgt
     7081 tacgggcggc acgcccaatg gtctggatga gtccacgctc gttacgaagg aaaccttcct
     7141 tgtcagcatc gagaatggca accaagctaa cctcaggaac gtcaatccct tcacgaagga
     7201 gattgattcc aaccaagaca tcaaagacac ccaagcggag atcacggata atctccgtcc
     7261 gttccaaggt cttgatatcc gagtgcatgt acttgacctt gatgcccatt tccttgaaat
     7321 agtcggtcaa gtcctctgcc attttcttgg tcaaggtggt gataaaggtt cgttcattct
     7381 tttcaacacg ggcattgatt tcacctaaga gatcatcaat ctgtcccata gtcggacgga
     7441 cttccacctc aggatccaaa agccctgtcg gtcgaatgat ttgctcaatc accgtctcag
     7501 tctgttcatt ttcatagtca ccaggtgtcg ctgatacgta aacaatctga tgcacatggc
     7561 tttcaaactc ctcacgacgg agaggacgat tgtccaaggc agacggtaaa cggaaaccat
     7621 aatttactag catttcctta cgcgaacggt ctccattgta catgcctttt atttgtccca
     7681 tagtcatatg actctcgtca atcataatca aaaaatcatc tgggaaaaag tcgagaagcg
     7741 tataaggagg ctcaccttca ctacgtccat ccatgtggcg agaataattt tcaaccccat
     7801 ttgtatagcc catctcgcgc agcatttcga tatcgtactc tgtccgttgt ttcaagcgct
     7861 gggcttcaag caatttacct tccttctcaa agacagctaa ctgctcttct aattctgctt
     7921 gaatcttggc aacggcaact tccatatggt cgtcattggt cacaaagtga gtagctggga
     7981 aaatcgccaa atgatccacc tctcccaata cctgacctgt cagagcctca acctcacgga
     8041 tacggtcaat ttcgtctcca aaaaattcta ctcgaaaggc atgttcatct cgggaagctg
     8101 ggaaaatctc taccacatcc ccacgaacgc gaaatcttcc gcgttggaaa tcaatatcat
     8161 tacgttcaaa ctgaatatcg accaagtcat tcaagagttt atcacgagaa atctctagac
     8221 caggacggag actaacgaca ctatcagcgt attccttggg cgaacccaaa ccatagatac
     8281 aagagactga ggccacgaca ataacatcat tacgctccaa aagggctgag gtagctgagt
     8341 ggcgaagctt gtcaatctcg tcattgacag aactatcctt ctcaatatag gtatcgctag
     8401 aagggacata ggcctctggc tggtaataat catagtagga tacgaaatac tcaactgcat
     8461 tttcagggaa aaattcctta aactccccat agagctgacc agccagagtt ttattgtggg
     8521 caataaccag agttggttta ttgactttag aaatgacctg actcatagta taggtcttcc
     8581 ctgttccagt cgcccccatc agaatctgag ctttttctcc cccctcaatg ttatccacca
     8641 actgctcgat agcttggggt tgatctcctg atggttgata ttttgatact agtttaaatt
     8701 gattatctgt aatgtgattg atcataagaa tcctctctcc atgtgctatt cctattttag
     8761 catacttata gtattttcac gaagaaaagg acggaccgaa gtcacatcct ttcattttct
     8821 ttctttaatt tattagcaag atagacaatc agcagtagta ataccagact tgtcataatg
     8881 gaaccttcta tgccaaaaga accacctgat agccaatctt gattgccttg tggtaaaaag
     8941 gtcatcagag acgttcctga cggttgacca ctaactaaaa tcccaaagag attaccctga
     9001 gcaaaattcc aagcaccatg aatacctgca acaccccaaa ctgtatcagt tttgagaagg
     9061 taaagagcca tggcaactcc gaataaaaag agatttacta gagatagagg ggtgaggcca
     9121 gaattgccca tatgaagcag ggtaaagaac aggctagata taagaatagc tagttttaga
     9181 ttggttcttg aggccaattg aggaagtagc caagcacggg ccaccacttc ttctgctgtc
     9241 ccctgtaaaa tccaaaatgg gatagtaaag acgacaaagg caagagaata aggattcaag
     9301 tgaatggatt ccaaacgata ttgacctaag accactaaac ctaacaaggt cagaagaaaa
     9361 agtgccaggc ctagactaaa tcctttcaga agattgctga ggaaattctc tctataaaat
     9421 cccaaggttc gaataggtct tttctcaact tttcttgtcc atctgaacac agtgttaaga
     9481 ataaaaccaa aggccagtaa tcctaaaatt aaacgaaagt cacttgtttt atccgtcaag
     9541 ctctgatgca aggtctgcaa gtagcttgca agattttgac cagcctctcc aaaatttcta
     9601 gcaagtccga tgagagctaa caaactaata ccatataaag tataagccac aaactctcct
     9661 atgaagacaa aaacaaaggc taacaagggg cttgtgtaaa tgtttaaatt catttttgaa
     9721 gcttggaagt ctttaaatat tcttttgttc ttcatatccc cgtcctcttt tcttctatat
     9781 acactattat tataacactt tttaatagca attcaagaaa gaaaaggaaa aatcaatgtt
     9841 atattttctg acacgaaaaa tataaaaatt tgcctttttt tactttttct gatataatga
     9901 gagaatattc ggaaaaggag actaaaaatg aagaaaaaat ttctagcatt tttgctaatt
     9961 ttattcccaa ctttctcatt aggtattgcc aaagcagaaa cgattaagat tgtttctgat
    10021 accgcctatg caccttttga gtttaaagat tcagatcaaa cttataaagg aattgatgtt
    10081 gacattatta acaaagtcgc tgagattaaa ggctggaaca ttcagatgtc ctatcctgga
    10141 tttgacgcag cagtcaatgc ggttcaagct gggcaagccg acgctatcat ggcagggatg
    10201 acaaagacta aagaacgtga aaaagtcttc accatgtctg atacttacta tgatacaaaa
    10261 gttgtcattg ctactacaaa gtcacacaaa attagcaagt acgaccaatt aactggcaaa
    10321 accgttggtg ttaaaaacgg aactgccgct caacgtttcc ttgaaacaat caaagataaa
    10381 tacggcttta ctattaaaac atttgacact ggggatttaa tgaacaacag cttgagtgct
    10441 ggtgccatcg atgccatgat ggatgacaaa cctgttatcg aatatgccat taaccaaggt
    10501 caagacctcc atattgaaat ggatggtgaa gctgtaggaa gttttgcttt cggtgtgaaa
    10561 aaaggaagta aatacgaaca cctggttact gaatttaacc aagccttggc tgaaatgaaa
    10621 aaagatggta gtcttgataa aattatcaag aaatggactg cttcatcatc ttcagcagtg
    10681 ccaactacaa ctactctctc aggattaaaa gctattcctg ttaaggctaa atatatcatt
    10741 gccagcgatt cttcttttgc accttttgtt ttccaaaatt caagcaacca atacactggt
    10801 attgatatgg aattgattaa ggcaatcgct aaagaccaag gttttgaaat tgaaatcacc
    10861 aaccctggtt ttgatgctgc tatcagtgct gtccaagctg gtcaagccga tggtatcatt
    10921 gctggtatgt ctgtcacaga tgctcgtaag gcaacttttg acttctcaga atcatactac
    10981 actgctaata ccattcttgg tgtcaaagaa tcaagcaata ttgcttctta tgaagatcta
    11041 aaaggaaaga cagtcggtgt taaaaacgga actgcttctc aaaccttcct aacagaaaat
    11101 caaagcaaat acggttacaa aatcaaaacc tttgctgatg gttcttcaat gtatgacagt
    11161 ttaaacactg gtgccattga tgccgttatg gatgatgaac ctgttctcaa atattctatc
    11221 agccaaggtc aaaaattgaa aactccaatc tctggaactc caatcggtga aacagccttt
    11281 gccgttaaaa aaggagcaaa tccagaactg attgaaatgt tcaacaacgg acttgcaaac
    11341 cttaaagcaa acggtgaatt ccaaaagatt cttgacaaat acctagctag cgaatcttca
    11401 actgcttcaa caagtactgt tgacgaaaca acgctctggg gcttgcttca aaacaactac
    11461 aaacaactcc ttagcggtct tggtatcact cttgctctag ctcttatctc atttgctatt
    11521 gccattgtca tcggaattat cttcggtatg tttagcgtta gcccatacaa atctcttcgc
    11581 gtcatctctg agattttcgt tgacgttatt cgtggtattc cattgatgat tcttgcagcc
    11641 ttcatcttct ggggaattcc aaacttcatc gagtctatca caggccaaca aagcccaatt
    11701 aacgactttg tagctggaac cattgccctc tcactcaatg cggctgctta tatcgctgaa
    11761 atcgttcgtg gtggtattca ggccgttcca gttggccaaa tggaagccag ccgaagcttg
    11821 ggtatctctt atggaaaaac catgcgtaag attatcttgc cacaagcaac taaattgatg
    11881 ttgccaaact ttgtcaacca attcgttatc gctcttaaag atacaactat cgtatctgct
    11941 atcggtcttg ttgaactctt ccaaactggt aagattatca ttgctcgtaa ctaccaaagt
    12001 ttcaagatgt atgcaatcct tgctatcttc tatcttgtaa ttatcacact tttgactaga
    12061 ctagcgaaac gcttagaaaa gaggattagt taatggcaaa attaaaaatt gatgtaaatg
    12121 atttacacaa gcactatgga aaaaatgaag tcctaaaagg aattacgact aagttctatg
    12181 aaggagatgt tgtttgtatc atcggtcctt caggttctgg taagtcaact ttcctccgta
    12241 gcctcaatct tttagaagaa gtcactagcg gtcacatcac tgtgaacggc tatgatttaa
    12301 ctgaaaaaac aaccaatgtt gaccacgtcc gtgaaaatat cggcatggta ttccaacact
    12361 tcaacctctt ccctcatatg tctgtattgg acaacatcac ctttgctcct attgagcaca
    12421 agttgatgat taaggaagaa gctgagaaat tgggaatgga gttgcttgaa aaggttggac
    12481 tagcagataa agctaatgcc aatccagata gcctatcagg tggtcaaaaa caacgtgtgg
    12541 ccatcgctcg tggcctagca atgaatccag acatcatgct cttcgatgaa ccaacttctg
    12601 cccttgaccc tgagatggtt ggagacgtac ttaacgttat gaaggaattg gctgagcaag
    12661 gcatgaccat gattatcgta acccatgaga tgggatttgc tcgtcaggtt gccaaccgcg
    12721 ttatctttac tgcagatggc gagttccttg aagacggaac acctgaccaa atctttgata
    12781 acccacaaca ccctcgtctg aaagagttct tagataaggt cttaaacgtc taaactcaaa
    12841 ctgtaagaat ttccttgcag tttttctacc tcgtattgga atttttgatt tttcggaaaa
    12901 ttatgttaga attaagttta tgaaatgagg tttcctcata cctagcaaga ctaggaataa
    12961 aaatagaaat taggtagcta gatgtcatct aaggttattg ttacaatttt cggtgcgagt
    13021 ggagacctgg ctaaacgcaa gctctaccct tcccttttta gactatataa atccggcaat
    13081 ctttccaagc actttgccgt tattggaact gcccgtagac cttggagtaa ggaatatttt
    13141 gaatctgtag ttgtcgagtc catccttgat ttggcagata gtaccgagca agcccaagaa
    13201 tttgctagcc acttctacta tcaaagccat gatgtcaatg attcggaaca ttatattgct
    13261 ttgcgtcaat tacaagctga gcttaatgaa aaataccaag ctgaacacaa taagctcttc
    13321 ttcttgtcta tggcacctca gttctttgga accattgcca aacacctcaa atctgaaaac
    13381 attgtcgatg gcaaaggttt tgagcgcttg atcgttgaaa aaccatttgg tacagattac
    13441 gcaactgcaa gcaagttgaa tgacgaactc ctagcaacat ttgacgaaga acaaattttc
    13501 cgtatcgacc attatcttgg taaggaaatg atccaaagca tctttgcagt tcgctttgca
    13561 aacttgattt ttgaaaacgt ttggaacaag gattttatcg acaatgttca aattaccttt
    13621 gcggagcgct tgggtgtaga agaacgtggt ggctactatg accaatccgg tgccctccgt
    13681 gacatggtcc aaaaccacac tctacaactt ctttcgctcc tcgccatgga caaaccagca
    13741 agcttcacaa aagacgagat tcgtgctgaa aagattaagg tctttaaaaa cctctatcat
    13801 ccaactgatg aagaactcaa agaacacttt atccgtgggc aataccgctc tggtaagatt
    13861 gatggcatga aatacatctc ttatcgtagc gagccaaatg tgaatccaga atcaacaact
    13921 gaaaccttta catcaggtgc cttctttgta gacagcgatc gattccgtgg tgttcctttc
    13981 tttttccgta caggtaaacg actgactgaa aaaggaaccc atgtcaacat cgtctttaaa
    14041 caaatggatt ctatctttgg agaaccactt gctccaaata ttttgaccat ctatattcaa
    14101 ccaacagaag gcttctctct tagcctaaat gggaagcaag taggagaaga atttaacttg
    14161 gctcctaact cacttgatta ccgtacagat gcgactgcaa ctggtgcttc tccagaacca
    14221 tacgaaaaat tgatttatga tgtcctaaat aacaactcaa ctaactttag ccactgggat
    14281 gaagttggtg cgtcatggaa gttgattgat cgtattgaaa agctctgggc tgaaaatggt
    14341 gccccacttc atgactataa agctggaagc atgggacctc aagccagctt tgacctactt
    14401 gaaaaattcg gtgccaaatg gacttggcaa ccagatatcg cctatcgtca agatggtcgc
    14461 ttagaataaa aaaatttcct gcaagtttat gccttgcagg atttttgctt ctgattagat
    14521 taaaccttcc aagagacctt tcataaagtt ttctgagtta aactctccaa tatcatcgat
    14581 tttttcacca aaaccaatca attttacagg aatattgagt tcttcacgaa tggctagaac
    14641 cacacctcct cgagcagttc catcaatctt agtcaaaaca attccggtta aaggtgtgat
    14701 tttcgaaaat tctttggcct gtactagggc attttgacct gttgatgcat caagtgccaa
    14761 gaaggtttca tgtggtgctt ctggcacaac acgtttgata atacgaccaa tcttttccaa
    14821 ctcagccata aggttatcct tattttgcag acgaccagca gtatcaatca tgagaatatc
    14881 gataccttca gccacggcac gttccatacc atcaaagacc acgctggctg gatcagcttt
    14941 ttcaggtcca gttactactg gaacatctac tcgtcggccc cattcagcta gctgagctac
    15001 tgcacccgca cggaaggtat ctgctgcaac cagcatgacc ttcttaccag cttgtttgta
    15061 gcggtgggct agttttccga tagaagttgt tttcccaaca ccattcacac caacaaagag
    15121 cataactgtc aagttatctt ggaagtggat gctttcatcg tagctaccat ccttttcata
    15181 aagctcaacc aatttctcaa tgatgacacg acgaagtaca tcaggtttct tggcattttc
    15241 aagcttggct tcgtaacgta gttcctccgt taagttagaa gcgacttgga caccaacatc
    15301 actcataatc agcagttctt ccagttcctc gaaaaattct tcgtcaacag agcggaagtt
    15361 agcaaagaag gcattcaagc gggcaccgaa acctgtgcga gttttcttaa gactgcggtc
    15421 atatttttcc tgaacagttt cttctgtttg aggagcttct ggttcaagca cttcagaatt
    15481 actttcttct acagttcctt cgtgctcaag cttctcttcc tctggtaatt cttctgagtg
    15541 tggaaattct tcgacttctt cttgagaaac ccctacaact ggctctgaat ccagactttc
    15601 ttcaactgtg tcttggattt cctcttcttg gaacacagct tgttcaataa tttcaacctc
    15661 tgcttcttct tgagaaactt cctcaacttc tgtgaaggta ggatcaacat attcagacaa
    15721 atcaagattt tccagagctt cttttacaac ttcttcgatt ttaggttctt ctttttttcc
    15781 gaatagacgg tcaaataatc ccatatctta gttctccttt agcacatatt cttcgatagc
    15841 ccaggcgaca gcttcttcat cattggtcat aggagttacc acatttgcga ctgccttgac
    15901 ttcaggaaca gcgttttgca tggcaacacc gagccctgcc cattcaatca tagagagatc
    15961 attggcctcg tcaccacagg ccatcacttg actttgatca attccaagat ggctaattag
    16021 ttttgccaaa cctgttgctt tatgaacatt ctttggtgac cattctagca acatttcacg
    16081 tgatttaaag atttcatatt ggtcaaacaa ttctggagaa atcttctgaa tggctgcatc
    16141 caagggttct tgagcaaagg cggtcacgca tttgttgtag gtcatttgat tagacaggtc
    16201 ttcaaaatca actggaacaa aagtcaaagc tggattgaat ttggcataaa gactttcttg
    16261 gtccgattga atttgataaa cagttccttc tgagatagcg tcaagaggca gtgataattt
    16321 ctctgtttct tcatacaagc gtgccacatc atcatatgaa aagactgtct tatcaaggat
    16381 ttcacctgta tttttctgaa ccaaaccacc attaaaagta atggtatact catcttcctg
    16441 accgtcagtc cctagctcat ggagaaagaa atccatagct tttaagggac gaccagttgt
    16501 caatacgacc ttgataccac gatcacgcgc agctttcaag gtttccttgg tacgatccgt
    16561 cagcctttta tcagtagtca gcaaggtccc gtccaagtcc aatgcaatca attttatatc
    16621 tgccattata agccctccat ataagctata accgactggt ccttatggtg accaatcaca
    16681 gtctctgcta attctaaaat ctctggtcgt gcattttcag gagctacagg atgtcccaca
    16741 acctgcatca tatgcaagtc atttagattg tctccaaaag ccatgacctg atccattgta
    16801 ataccaagtt ttttagctaa ttcaacaata gctaccccct tatcgacata gtccagaaca
    16861 atatcaatag attcaaagcc agttgtcata gccttgacac cagaaacatg ttcattgacc
    16921 caagcttcac cagcttctaa cgttccttct gtgaagttgg ttgtaaattt gaaaatgtca
    16981 tctgtgatat cttccaaact cgctactttt tggatatttt cattataatg ctgactcact
    17041 ttcaaatagg tctcatcaac cgtatctaga acatatgaac ccttcttacc cgtcaagagc
    17101 agtttattga tatctacata aggtgacgtt ttcagctttt caaaagttgc cagataaaag
    17161 tcacgagaca tagtcgcttc atacaagtcc tgaccttgat actctaccaa actgccattt
    17221 tccgcgatga aaataatgtc atcacgaaca tcagcaaata atttttccag agacagaaat
    17281 ccccgacccg aagccaccgc aaagtaaatc cctttttcct tgtaggaagc caagagagac
    17341 ttgagacgat ccatatcaaa gcgtccattc ccatctagga aggttccgtc catatccgtt
    17401 gctactagtt taattgtcat ccttcaatac tttctaaatc ttttaactta actgaaacaa
    17461 tttttgagac acccgattct tgcatggtca ctccatagat agaatcagcc gctgccatgg
    17521 ttcccttacg gtgggttacg acgataaact ggctgtcctt gtcaaatcga ttgaggtaat
    17581 ccccaaaacg tttaacattg gcttcgtcca gcgcagcctc tacctcatcc aagatgacaa
    17641 atgggatagt cttaactcga atgatagaaa aaagcaaagc aagagccgat agagcttttt
    17701 caccaccact catgaggcta agagactgga ttttcttacc tggaggttga acagaaattt
    17761 caaccccagc tgtcagcaag tctccttcag tcaaaatgag gtcagcctga cctccaccaa
    17821 acatctgctt gaaggtcact ttaaaggact cacgaatggc ctcaaaggtt gatttaaagc
    17881 gttccttgac ctcatcattc atctctgtga tggtttcaag aagcaggttt ttcgcagaca
    17941 aaatatcatc acgttggcta tttaggaaat ccagacggtt gtgaacttct tcgtactgtt
    18001 caatagcgtc taaattgaca ggacccagtg agcgtatagc cttctctaaa tccttaactt
    18061 cttgctctgc cagattgaga ttttccaact catgcgcctt ttctaaagct tctgtgtagc
    18121 tgatctggta ctggtctgtt aattgacttt gtagatggcg caagcgctcg ctaacctttt
    18181 ctttctttgc ttcagcacga gtttgcttgc gaatccactc ttcattctgc tggcgagcct
    18241 gatccaaatg actagcaata tcatccagtt gaccctcaat atcatccaac tcaaactgct
    18301 tgcgaatcaa accttgttgg agatttgttt tttgagtttt ggcttcatca gcctgttgac
    18361 tgagcaaatc cgtatcaact ttctcaagat tgtcaacctt ttcttgaaga aggcgctgaa
    18421 tttcttcttg ctcaatatca agattatcta gttccttacc taagcgttca atatcagtca
    18481 cttcataacg tttttgccct tgcagttctg tcttaagcaa acgagcttgc gctagctctt
    18541 cctgcaagtt ttgatagcgt tcttggatgg catttttgtt agacttaatc tcttcaatct
    18601 cagcttccag attttgcttg tcactggcga ttgcagcaag acgctcttgg catttttcct
    18661 tatccgcttg ccaatctccc tcggaaagac gatctttttc cttttcttgg agtttccaaa
    18721 gagtttctag ctcttcaact tgctgactag tttgctgata agcgaggaac aagccttgct
    18781 cctgaatacg tgcctgctct ccttgagatt taatagcttc taatgactcg gtcaatctag
    18841 ccatctggtc ttgtaaggtc ttcaaagtcg cctcttctga acccaagctt gcttcttctt
    18901 cagcaatttc tttttgtaat tgctccagtt ctggcttgat gaaaatactg ttattctggc
    18961 gattggcacc acccgcatag gaaccacccg tgcgtaattc tgtcccatcc aatgtcacca
    19021 tacgaacctg ataacgaact tggcgagctg ctgcacgcgc atgttctacg gtatcaaaga
    19081 tagccgtcgt agctagcaag ttcttgaaaa tggcttccag tctagtatca aaagtcacca
    19141 actcatctgc catcccaagg aaacctgggc ttacagcgat agcatcttgg ttctgactgg
    19201 aaatcgtacg cgccttgata gtggtcaaag gaagaaaggt tgcacgaccg gctctgttcc
    19261 gtttaaggaa gtcaatagcc ttggttgccg actcttcatc ttctacgatg atatgttggc
    19321 tactcgctcc aagcgcaatt tctagggcag tttgataatg catatcaaag gtcagatgct
    19381 cactgactgc accaataatc ccacctaggc gatctttttc ttggagaaca ctcttaacac
    19441 ctgcataaaa gttactatga tttctcagga tattttccaa actttgagct ctggcctgct
    19501 tgtttttgag attatccaga cggtcaaaga gttggctttg ttgagcttga taggaagttt
    19561 tctgctcctc ttgctccttg gcaatagctt ggtagtcagc caataatttc tgaacctgct
    19621 ccttggcagt ttcaagctct tccttttgct gactagcctt ctctttagct atagccaatt
    19681 gctctttcag cttttctagt tgatctgctt gtttttgaga aagctgacga ctattttcca
    19741 actcattctc gatgcgggtc agttggtttg agacatccgc ttcttcttgt aaaagcgcca
    19801 caaagcgttc acgcaaaagc tcaatcatct gatcaggatc atctgaaaaa gctagcaatt
    19861 cagcttctaa acgattgagt ttttgattat tttggactag attttcctct aaaagtacta
    19921 aagagctttc tttatcagat ttttcttggc tgagtgaatt tctcttatcc tccaaaacag
    19981 ccaaacgagc ttgtgcttcc tgttgattca gggctacttg ctcagattct aatttcgata
    20041 gggctaattt tctctctaaa tcactaatca gactggtcaa atccatcaaa ctgccttggt
    20101 ctttggccat ttcagcctgt aaatcttggc gttgcttttt aagagtttga ttttcttctt
    20161 ctaatttttc acgcttttgg taataactca tcaagagttc ttgaacctga gccaactctt
    20221 cttctgtcga ctctagttca gccttatttt ccttgatttg agcaaccaga acatctaaat
    20281 aaatagcctt acgttgtcct tccaagtcta aaaacttacg ggcattctca gcttgctttt
    20341 caagaggctt gatttgatta tccaactcgt agataatgtc ctctaagcgg tccagattat
    20401 cctgagtttg ctgcagttta ctctcggttt cttttctgcg agtcttgtat tttaaaactc
    20461 cagcagcttc ttcaaaaata gctcgtcgtt cctcaggctt ggaattaaaa atctcctcaa
    20521 ccttcccttg ggaaataata gagaaggaat ctcgtcccaa tccagtatcc aagaagaggt
    20581 catgaatatc acgcagacgg actttcttgc cgtcaatctt gtattcgcta tctccactac
    20641 gatagatatg gcgttccacc ctgatttctt gacctgcatc cttgataaat ccgtcatgat
    20701 tatccagagt cacaactaca gaagcataat tgagcggttt gcgactttcg gttccagcaa
    20761 agatgacatc cggcatcttg cccccacgga gactcttgac actagactcc cccaaagccc
    20821 aacgcagact ttctgtaata ttggactttc cagatccatt gggtccaaca actgccgtca
    20881 caccttggtc aaaaacgacc ttggtcttat cagcaaaaga cttgaacccc tgaatttcga
    20941 tttcctttaa atacatgaat ccagcccctt ctcaacggca tttttggcag cttcctgctc
    21001 tgctaatttc ttagaacgac cttggccttg accgatgctc ttaccttcaa caagaacttc
    21061 tacatcaaag accttatcat gagcaggccc tgtttcagaa atcacctgat aacgaatagc
    21121 cacatcacca ttgacctgaa gcaactcttg gagatgggtt ttatagtctg taatcatctc
    21181 aaactcgcct gcttcaacct taggaatgat gacttgatag ataaattcct tgaccttggc
    21241 cacatcctta tccaaaagaa gggcaccaag aaaggcttca aaggcatcac caagaatggt
    21301 gtcacgattg cgaccacctg atttttcttc ccctttaccc aacttgataa actggttaaa
    21361 ctggcaatca cgcgcaaaac cagctaaact ctcctcacgg acaatcatag cacggagttt
    21421 tgataggtca ccttcaggct ttttaggata ttttttatat agatattctg aaatcaataa
    21481 ctgtagaaca gcgtctccta aaaattccaa gcgttcattg tgtgaaattt ttaagaggcg
    21541 gtgctcattg gcataactcg tatgagtaaa ggcagtttcc agtaaatttt tgtctgcaaa
    21601 ttcgattgca aaatgattct ttagtacagt ttgtaattct ttcataccaa cctctttcta
    21661 actgataata gtccttttta ttatatcaaa aaaagccccc tgagtcactc taaaacggga
    21721 ctggaaagca tttgggaatt ctttagacag agattctcag ttttagcggc aaatttgggt
    21781 caggataaag aaaaaagccc tattaaaggc tttttaggat gtttacatcc accctgaggg
    21841 aatcgaaccc ccatctcaag aaccggaatc ttacgtgata tccattacac taagggtgga
    21901 aacttgtttt attataacag aaatttgctc taataacaag ttttttggtc aaagaccccg
    21961 tcttagtggg aagcatcccc attccagatg gagtttttca cgatcacata atcaacgtgt
    22021 ttaaggtcag caacctgacg tccacctgca taagaaatag cactttgaag gtcttgttcc
    22081 atctcagtta aagtgtcttg cagatgacct ttagcaggaa gcaagatacg tttgccttcc
    22141 acatttttgt aagcaccttt ttgatattgt gaggctgaac cataatattc tttgaactgt
    22201 tcaccatcga cttcaatcgt tttccctgga ctttcaatgt gtcctgcaaa gagggaacca
    22261 atcatgatca tgctagcacc gaagcggata gacttggcaa tatcaccgtg agtacgaatt
    22321 cctccatcag cgataatcgg tttacgcgca gccttggcac accagcgtag agcagccaac
    22381 tgccaaccac ctgtaccaaa accagtctta accttggtga tacaaacctt accaggaccg
    22441 attccgacct tagtagcatc cgcaccagca ttttccaatt cacgcacagc ttctggtgtt
    22501 cccacatttc cagcaatgac aaaggtatct ggcaattctt tcttgatgtg ttgaatcata
    22561 gaaatcacgc tatccgcatg accatgagca atatcaatag tgatatactc aggagcatca
    22621 gccttgagct ggctaacaaa atcatactca tagtccttaa caccgacaga gatagaagca
    22681 atgagtcctt gatcgtgcat gcgtttaata aaaggaatgc gtcctgcctc atcaaaacgg
    22741 tgcataatgt agaagtaacc acctttagcc agttgctctg ctacattttc atccaaaatc
    22801 gtctgcatat tcgctggcac aacaggtagt ttaaaggtgt gatttcctaa agtgacactt
    22861 gtatccgctt ctgcacggct tttaatgaca catttatttg gaatcaattg aatatcttcg
    22921 taatcaaaaa ttggaaattc atttaacata tcgatgtctc gtttcttttg taatgaccta
    22981 cctatgctct cgcatcacta cgccttttcc gacgtttcct taatttatta taaactaaag
    23041 tacagttttt gtcaaattat tttatgaatt aaaatatatt gttcgggttt tgcttgtgtt
    23101 aaaaataaaa gaaagagggg aaattatttt ctccccactt cttcatcaat aatcgcttta
    23161 aaattttctt ccgaattttc catcatttta caaaatgcac tatagaatga ggcattctga
    23221 gggattcgaa tagaccactt cttcaattga gctccatagc cagctacttt tcctatttca
    23281 ctatttactg actgctccat actaggaaaa atcagtccag ccttctcagc ttttaaaata
    23341 taagaatagg aaatcagctg gaataagtcc tcacggttga ttcctttttc agtcaattcc
    23401 agttttttat attttgcatc tagaacaatc tttcgttctc tgtcataaaa atctggatat
    23461 acttttcgtt tcccaacaga aaatactgaa attccatccg tcttatcctt atttctggga
    23521 tgtacaaaac cttttggcaa caaggtgtaa acatactctt cccaaagcca ggcaacatca
    23581 aagagaatac catagatttt ttgatcttga taccctaaac cgtgcttttc ttggtttagg
    23641 atcatcagac aaagttcttg taagtttctg tactcgtgaa agtatgcatg acgtataggt
    23701 ttagattgat ttccccgaat aatcttagca cgatcagcta gtttataaga gggcgttaca
    23761 cgcacgattt cagatacgtt ttcacgacta gttgagagat tatctagtac cccttgacca
    23821 atgcttttct gattcttaat gtattcaata gtgtgacgga ccaactgcat gaggggatta
    23881 tcataggtga actctctcgt tgcgtaggca atatttcccg tgaaaggaag atttttcttg
    23941 agatggcttc ttacatcaat cactccctta acatgactgt cgttatgaga aaatcgatga
    24001 tattccttat aaagaccttt tcgaatagca gcttgtagat acttggggaa gagatacatc
    24061 aaaagttgat aaagcctctc ttcacgagac aaagcaacat ctaaactagt gagattgata
    24121 tgaagaacct tgtttaagag ataatgcaaa aaatggtcat tactctcatc agaaaatcgt
    24181 gaggaaatcg ttaatctttc ctgaccatat ccaagaaaac caatcacgtt ccctgtcttg
    24241 attttctgat tgactgtttc aaaaatcttt tggtccttat ccaaatcagg agtatgagtc
    24301 aaatcatttg gaaaaatgaa aatacgttca tcttgggata gactttccaa ggttctgtct
    24361 aaaagaagat tgcttagttt aggatattct tcaacaaatt tttctttaat aatcttgtgt
    24421 tgattatcag taatccgcat catcgttttc atcaccttca ttgtcatcag ctactgcctg
    24481 atctttttgc tcattatttg tcagttcaaa tgcttttttc aaagtttcca aagtttcaac
    24541 ctcatcataa gaacctcgca agtagtcttc taggagaggc ttaatataat cagaccagag
    24601 taattcatag tcaaaatcta catccttcaa cttaagaaaa taacttggtc caatatgata
    24661 atgactgttt aattcctgaa cattttcgat agcagcgttc aagtttctta gacgaatttt
    24721 tgcttcttct gcatggatat tcagctcttt atccaacatg ccaacttgac cctcggcagt
    24781 aacttcaaca aaacgaaaac gacgacgcat agcaaaatca aaggtatcca ctgaacgatc
    24841 aatatcattc atagttccga tgatgtaaac attttcgggg atatagaact tttcatcagt
    24901 ttcgtgtaga tttgcatatt gggtagaaac acttcctttt tcaccacgat agccagggtc
    24961 gatagagaaa aagagttcgc caaaaatctt agaaatctcc ccacgattga tttcatcgat
    25021 gatgaagacg aatttcttat cagtatcaat ttctgttggg gaaacatagt ctttcaaacc
    25081 aaatctcttt ctcaatgttt ctaggacagt ttttccacca cttttgtagt attcttgctt
    25141 attataattt ttatctttat acaactcgta aacatatttg ctaggtagtg accatcctgg
    25201 aacaccacta tcataattta ctgacaaatt ttgtctacta ttaacagata agtaagatgt
    25261 ttttgttata tattcttttt cttcagcaac atttatatat tctaagtaag aatcccaagc
    25321 ctcatcaaaa ttatcttgtc ctccaatcaa ttgggtttct tttgctttct gacaaaaatc
    25381 tttaaaaata ccgtcctgta gcctaaactc aatagctcca tccccatttg atactggtct
    25441 taaaccttct acaaaatccg tataatcata tgatgggtga aattgtacaa atccgatttg
    25501 gtcttcgttg ccatccgtta attctttagc aatttcttta gcaagataag tttttcccgt
    25561 gccaggagca ccgcggagga tgaggtttgg agactttaat agagattgag ttaattgatg
    25621 actaaaattg tttgatgaat ccattgtact attgtcttcc ttattttcca taaaaagctt
    25681 agaatactca aaaagaatag ttcctaattt cgatggctcc aactcaggat aagttttgga
    25741 caccagttca attattttat gattttgcag ataaggtcca ccttgatttg tctgagaaac
    25801 aaagtggttc caaaattctt tctgactatt aatatttaca ccaaagaaag gatctccctc
    25861 agtatagata caaagtaatt ttgtcaccat agcagaacga ccaataaatt catttgttga
    25921 tcttttcata tcaaaaatag gattttcaaa gttaaaacga ataccttctt tgataatttc
    25981 atacaaatct gattttaatt ttgaaaatcg ctgatccaac tctgaaatct catta
//
LOCUS       DBEJAU010000030        25389 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC323 isolate 683620
            SAMN38261939-rid24807223.denovo.030, whole genome shotgun sequence.
ACCESSION   DBEJAU010000030 DBEJAU010000000
VERSION     DBEJAU010000030.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261939
            Sequence Read Archive: SRR26833919
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 25389)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 25389)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576303.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576303.1
            Genome Coverage       :: 154x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/19/2025 01:05:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,121
            CDSs (total)                      :: 2,078
            Genes (coding)                    :: 1,943
            CDSs (with protein)               :: 1,943
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 36
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 72 of 135
            Pseudo Genes (incomplete)         :: 63 of 135
            Pseudo Genes (internal stop)      :: 51 of 135
            Pseudo Genes (multiple problems)  :: 46 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..25389
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261939-rid24807223.denovo.030"
                     /strain="GPSC323"
                     /isolate="683620"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            complement(121..774)
                     /gene="phoU"
                     /locus_tag="ACL29Z_001284"
     CDS             complement(121..774)
                     /gene="phoU"
                     /locus_tag="ACL29Z_001284"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000946475.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006817 - phosphate ion transport [Evidence
                     IEA];
                     GO_process: GO:0030643 - intracellular phosphate ion
                     homeostasis [Evidence IEA];
                     GO_process: GO:0045936 - negative regulation of phosphate
                     metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate signaling complex protein PhoU"
                     /protein_id="HGR0069594.1"
                     /translation="MLRSQFEEDLEKLHNQFYAMGQEVLSQINRTVRAFVTHDRDLAK
                     EVIEDDAEVNEYEVKLEKKSFEMIALQQPVSQDLRTVLTVLKAVSDVERMGDHAVAIA
                     QATIRMKGEERIPAVEEEIKKMGREVKSVVEAALDLYLNGSVDDAYRVASMDEQINHY
                     FETIRDLATEEIKKNPEAIVTGRDYFQVISYLERIGDYAKNICEWVVYFETGKIVEL"
     gene            complement(786..1544)
                     /gene="pstB"
                     /locus_tag="ACL29Z_001285"
     CDS             complement(786..1544)
                     /gene="pstB"
                     /locus_tag="ACL29Z_001285"
                     /EC_number="7.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014294590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009898 - cytoplasmic side of plasma
                     membrane [Evidence IEA];
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0015415 - ATPase-coupled phosphate ion
                     transmembrane transporter activity [Evidence IEA];
                     GO_process: GO:0006817 - phosphate ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter ATP-binding protein
                     PstB"
                     /protein_id="HGR0069595.1"
                     /translation="MTDAILQVSDLSVYYNKKKALNSVSLSFQPKEITALIGPSGSGK
                     STLLKSLNRMGDLNPEVTTTGSVVYNGHNIYSPRTDTVELRKEIGMVFQQPNPFPMTI
                     YENVVYGLRINGIKDKQVLDEAVEKALQGASIWDEVKDRLYDSAIGLSGGQQQRVCVA
                     RVLATSPKIILLDEPTSALDPISAGKIEETLYGLKDKYTMLLVTRSMQQASRISDKTG
                     FFLDGDLIEFNDTKQMFLDPQHKETEDYITGKFG"
     gene            complement(1557..2360)
                     /gene="pstB"
                     /locus_tag="ACL29Z_001286"
     CDS             complement(1557..2360)
                     /gene="pstB"
                     /locus_tag="ACL29Z_001286"
                     /EC_number="7.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000852852.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009898 - cytoplasmic side of plasma
                     membrane [Evidence IEA];
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0015415 - ATPase-coupled phosphate ion
                     transmembrane transporter activity [Evidence IEA];
                     GO_process: GO:0006817 - phosphate ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter ATP-binding protein
                     PstB"
                     /protein_id="HGR0069596.1"
                     /translation="MSTYNWDEKHILTFPEEKVALSTKDVHVYYGKNESIKGIDMQFE
                     RNKITALIGPSGSGKSTYLRSLNRMNDTIDIAKVTGQILYRGIDVNRPEINVYEMRKH
                     IGMVFQRPNPFAKSIYRNITFAHERAGVKDKQVLDEIVETSLRQAALWDQVKDDLHKS
                     ALTLSGGQQQRLCIARAISVKPDILLMDEPASALDPIATMQLEETMFELKKNFTIIIV
                     THNMQQAARASDYTGFFYLGDLIEYDKTATIFQNAKLQSTNDYVSGHFG"
     gene            complement(2371..3255)
                     /gene="pstA"
                     /locus_tag="ACL29Z_001287"
     CDS             complement(2371..3255)
                     /gene="pstA"
                     /locus_tag="ACL29Z_001287"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009443446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0015415 - ATPase-coupled phosphate ion
                     transmembrane transporter activity [Evidence IEA];
                     GO_process: GO:0006817 - phosphate ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease PstA"
                     /protein_id="HGR0069597.1"
                     /translation="MRAKKLDKLATAVLYTIASIIVTILASLILYILVRGLPHISWSF
                     LTGRSSAFQAGGGIGIQLYNSFFLLVITLIISVPLSMGAGIYLAEYAKKGPVTNFVRT
                     CIEILSSLPSVVVGLFGYLIFVVQFEYGFSIISGALALTVFNLPQMTRNVEDSLKHVH
                     HTQREAGLALGISRWETVVHVVIPEALPGIVTGVVLASGRIFGEAAALIYTAGQSAPA
                     LDWSNWNILSVTSPISIFRQAETLAVHIWKVNSEGTIPDGTIVSAGSAAVLLIFILIF
                     NFGARKFGSYLHKKLTAA"
     gene            complement(3245..4162)
                     /gene="pstC"
                     /locus_tag="ACL29Z_001288"
     CDS             complement(3245..4162)
                     /gene="pstC"
                     /locus_tag="ACL29Z_001288"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018378778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0015415 - ATPase-coupled phosphate ion
                     transmembrane transporter activity [Evidence IEA];
                     GO_process: GO:0006817 - phosphate ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease subunit PstC"
                     /protein_id="HGR0069598.1"
                     /translation="MNQEELAKKMLLPSKNSRLEKLGKGLTFACLSLIVILVAMILVF
                     VAQKGLSTFFVNGVNIFDFLLGGTWNPSSKEFGALPMILGSFIVTILSALIATPFAIG
                     AAVFMTEVSPKGAKILQPAIELLVGIPSVVYGFIGLQVVVPFVRSVFGGTGFGILSGI
                     SVLFVMILPTVTFMTTDSLRAVPRYYREASFAMGATRWQTIWRVILKAARSGIFTAVV
                     FGMARAFGEALAIQMVVGNSAVIPTSLTTPAATLTSILTMGIGNTVMGTVNNNVLWSL
                     ALVLLLMSLVFNSVIKLITKERGKKNYAR"
     gene            complement(4162..5040)
                     /gene="pstS"
                     /locus_tag="ACL29Z_001289"
     CDS             complement(4162..5040)
                     /gene="pstS"
                     /locus_tag="ACL29Z_001289"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000746338.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter substrate-binding
                     protein PstS"
                     /protein_id="HGR0069599.1"
                     /translation="MKKRKKLALSLIAFWLTACLVGCASWIDRGESITAVGSTALQPL
                     VEVAADEFGTIHVGKTVNVQGGGSGTGLSQVQSGAVDIGNSDVFAEEKDGIDASALVD
                     HKVAVAGLALIVNKEVDVDNLTTEQLRQIFIGEVTNWKEVGGKDLPISVINRAAGSGS
                     RATFDTVIMEGQSAMQSQEQDSNGAVKSIVSKSPGAISYLSLTYIDDSVKSMKLNGYD
                     LSPENISSNNWPLWSYEHMYTLGQPNELAAEFLNFVLSDETQEGIVKGLKYIPIKEMK
                     VEKDAAGTVTVLEGRQ"
     gene            complement(5614..6918)
                     /locus_tag="ACL29Z_001290"
     CDS             complement(5614..6918)
                     /locus_tag="ACL29Z_001290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001160253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RsmF rRNA methyltransferase first C-terminal
                     domain-containing protein"
                     /protein_id="HGR0069600.1"
                     /translation="MQFPEGFVEKYKEILGDEARDFLASFEEEAVSAFRVNPLKEEQL
                     SFSDAITQTPWGHYGKVSGKSPEHATGLVYSQEPAAQMVAQVAQPSPGMKVLDLAAAP
                     GGKSTQLAAYLAGEGLLVSNEISSKRAKILVENMERFGATNVVVTNESADRLVKVFKG
                     YFDLIVLDAPCSGEGMFRKQPDAMDYWSLDYPSQCASLQREILEDAVTMLAEGGRLVY
                     STCTWAPEENEEIVNWLLEEYDFDLLPVEHINGMVAGIDLPETARMYPHQFKGEGQFV
                     AHLQFKGNNPAPKFKASKSNLSREQVALWQEFAQNHLKVNLPGILQTFGDQLYLLPEL
                     LPDLGKLKIARNGLHLGTFKKKRFEPSFALGLALKPSQVEQSVEIGQEAFVKYAAGET
                     VQLAESLPNGWYQVLVKGNGLGFAKVTGNVLKNYFPKGLRFK"
     gene            complement(6919..7692)
                     /locus_tag="ACL29Z_001291"
     CDS             complement(6919..7692)
                     /locus_tag="ACL29Z_001291"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="inositol monophosphatase family protein"
                     /protein_id="HGR0069601.1"
                     /translation="MESKFEFAKELVKKAGQYILDHMQEDLRVETKSSSTDLVTRLDK
                     EVQELLVGEILSRYPEDKICAEEGCLRASVQEGKVWVIDPIDGTNNFVAQQEDFAVMM
                     AYFENGQGQFGLIYDVVKGDCYHGGGEFPVCLNDRPLAPFKTKPLGDFLIAGNSGMLE
                     TNEWGLADLSRSVLGVRVYGSAAISFAKILSGRLLTYLTYLQPWDYAAASILGESLGY
                     RVVTLFGEAPDFQTRQPVMMVPLEMQEEIQSYIYERKRT"
     gene            complement(7682..7960)
                     /locus_tag="ACL29Z_001292"
     CDS             complement(7682..7960)
                     /locus_tag="ACL29Z_001292"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004252549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UPF0223 family protein"
                     /protein_id="HGR0069602.1"
                     /translation="MNKQYSYPLDLSWSTEELASVLSFFNDVEAAYEGKVEAKKLLDS
                     YKGFKAVVPSKSEEKRLGREFETVSGYSLYRAVQAAKEKGEGKISLGK"
     gene            complement(7960..8361)
                     /locus_tag="ACL29Z_001293"
     CDS             complement(7960..8361)
                     /locus_tag="ACL29Z_001293"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007556665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Spx/MgsR family RNA polymerase-binding
                     regulatory protein"
                     /protein_id="HGR0069603.1"
                     /translation="MITLFLSPSCTSCRKAKAWLEKHKVPFVEHNIMTSPLTRKELQH
                     ILSLTENGTDDIISTRSKIFQKLNIDVESISVSELLHLIEQYPSLLRRPIIIDAKRMQ
                     IGFNEDEIRAFLPRSYRKQELKEARMRAGIS"
     gene            complement(8571..9188)
                     /locus_tag="ACL29Z_001294"
     CDS             complement(8571..9188)
                     /locus_tag="ACL29Z_001294"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000850480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01906 family membrane protein"
                     /protein_id="HGR0069604.1"
                     /translation="MKTKLTFWGSMLFLLSLSILLTIYLAWIFYPMEIQWLNLTNRVY
                     LKPETIQYNFHILMNYLTNPFSQVLQMPDFRSSAAGLHHFAVVKNLFHLVQLVALVTL
                     PSFYVFVNRIVKKDFLSLYRKSLLTLVVLPVMIGLGGVLIGFDQFFTLFHQILFVGDD
                     TWLFDPAKDPVIMILPETFFLHAFLLFFALYESFFGYLCLKSRRK"
     gene            complement(9178..9951)
                     /locus_tag="ACL29Z_001295"
     CDS             complement(9178..9951)
                     /locus_tag="ACL29Z_001295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004258500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01457 family HAD-type hydrolase"
                     /protein_id="HGR0069605.1"
                     /translation="MKYKGYLIDLDGTIYKGKDRIPAGETFVHELQKRDIPYLFVTNN
                     TTRTPESVKEMLAQNFNIDTPLSTVYTATLATIDYMNDLGLEKTVYVVGEAGLKEAIK
                     AAGYVEDKENPAYVVVGLDWQVDYEKFATATLAIQKGAHFIGTNPDLNIPTERGLLPG
                     AGSLITLLEVATRVKPVYIGKPNAIIMDKAVEHLGLEREELIMVGDNYLTDIRAGIDN
                     GIPTLLVTTGFTKAEEVAGLPIAPTHVVSSLAEWDFDEN"
     gene            complement(9962..10699)
                     /locus_tag="ACL29Z_001296"
     CDS             complement(9962..10699)
                     /locus_tag="ACL29Z_001296"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016790 - thiolester hydrolase activity
                     [Evidence IEA];
                     GO_process: GO:0006633 - fatty acid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-ACP thioesterase domain-containing protein"
                     /protein_id="HGR0069606.1"
                     /translation="MGLTYQMKMKIPFDMADMNGHIKLPDVILLSLQVSGMQSIELGV
                     SDKAILEDYNLVWIIAEYDIEVVRLPRFAEEITIETEALSYNRLFCYRRFTIYNEAGQ
                     ELIHMMATFVLMDRDSRKVHAVEPEIVAPYQSDFDKKLIRGPKYESLEEPISKDYHVR
                     FYDLDMNGHVNNSKYLDWIFEVMGADFLTHYIPKKINLKYVKEVRPGGVITSAVERTG
                     LESKHEITSDGVINAQAIITWQEIKKV"
     gene            complement(10704..11834)
                     /gene="hemW"
                     /locus_tag="ACL29Z_001297"
     CDS             complement(10704..11834)
                     /gene="hemW"
                     /locus_tag="ACL29Z_001297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA];
                     GO_function: GO:0051989 - coproporphyrinogen dehydrogenase
                     activity [Evidence IEA];
                     GO_process: GO:0006779 - porphyrin-containing compound
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="radical SAM family heme chaperone HemW"
                     /protein_id="HGR0069607.1"
                     /translation="MQKKPTSAYVHIPFCTQICYYCDFSKVFIKNQPVDSYLEHLLEE
                     FRSYDIEKLSTLYIGGGTPTALSAPQLEVLLNGLTKNLDLSVLEELTIEANPGDLDAD
                     KIAVLKNSAVNRVSLGVQTFDDKMLKKIGRSHLEKDIYENIDRLKLAGFDNISIDLIY
                     ALPGQTMEQVKENVAKAIGLDIPHMSLYSLILENHTVFMNRMRRGKLPLPKEELEAEM
                     FEYIIAELERAGFEHYEISNFSKPGFESRHNLMYWDNAEYYGIGAGASGYVNGVRYKN
                     HGPIRHYLSAVEEGNACITEDHLSQKEQMEEEMFLGLRKKSGVSMARFEEKFGQSFAG
                     LYGEIVRDLVQQGLMQIEGDHVRMTKRGLFLGDTVAERFILE"
     gene            complement(11918..12307)
                     /locus_tag="ACL29Z_001298"
     CDS             complement(11918..12307)
                     /locus_tag="ACL29Z_001298"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000517372.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YtxH domain-containing protein"
                     /protein_id="HGR0069608.1"
                     /translation="MGKLSSILLGTVSGAALALFLTSDKGKQVCSQAQDFLDDLREDP
                     EYAKEQVCEKLTEVKEQATDFVLKTKEQVESGEITVDSILAQAKSYAFQATEASKNQL
                     NNLKEQWQEKAEALDDSEEIVIHITEE"
     gene            complement(12280..12706)
                     /locus_tag="ACL29Z_001299"
                     /pseudo
     CDS             complement(12280..12706)
                     /locus_tag="ACL29Z_001299"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000895042.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DUF948 domain-containing protein"
     gene            complement(12707..13495)
                     /gene="lgt"
                     /locus_tag="ACL29Z_001300"
     CDS             complement(12707..13495)
                     /gene="lgt"
                     /locus_tag="ACL29Z_001300"
                     /EC_number="2.5.1.145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000886660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008961 -
                     phosphatidylglycerol-prolipoprotein diacylglyceryl
                     transferase activity [Evidence IEA];
                     GO_process: GO:0009249 - protein lipoylation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="prolipoprotein diacylglyceryl transferase"
                     /protein_id="HGR0069609.1"
                     /translation="MLDPIAIQLGPLAIRWYALCIVTGLILAVYLTMKEAPRKKIIPD
                     DILDFILVAFPLAILGARLYYVIFRFDYYSQNLGEIFAIWNGGLAIYGGLITGALVLY
                     IFADRKLINTWDFLDIAAPSVMIAQSLGRWGNFFNQEAYGATVDNLDYLPGFIRDQMY
                     IEGSYRQPTFLYESLWNLLGFALILIFRRKWKSLRRGHITAFYLIWYGFGRMVIEGMR
                     TDSLMFFGLRVSQWLSVVLIGLGIMIVIYQNRKKAPYYITEEEN"
     gene            complement(13488..14423)
                     /gene="hprK"
                     /locus_tag="ACL29Z_001301"
     CDS             complement(13488..14423)
                     /gene="hprK"
                     /locus_tag="ACL29Z_001301"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA];
                     GO_process: GO:0006109 - regulation of carbohydrate
                     metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HPr(Ser) kinase/phosphatase"
                     /protein_id="HGR0069610.1"
                     /translation="MSVLVKEVIEKLRLDIVYGEPELLEKEINIADITRPGLEMTGYF
                     DYYTPERIQLLGMKEWSYLISMPSNSRYEVLKKMFLPETPAVIVARGLVVPEEMLKAA
                     RECKIAILTSRAATSRLSGELSSYLDSRLAERTSVHGVLMDIYGMGVLIQGDSGIGKS
                     ETGLELVKRGHRLVADDRVDIFAKDEITLWGEPAEILKHLIEIRGVGIIDVMSLYGAS
                     AVKDSSQVQLAVYLENYDTHKTFDRLGNNAEELEVSGVAIPRIRIPVKTGRNISVVIE
                     AAAMNYRAKEMGFDATRLFDERLTSLIARNEVQNA"
     gene            complement(14553..14729)
                     /gene="rpsU"
                     /locus_tag="ACL29Z_001302"
     CDS             complement(14553..14729)
                     /gene="rpsU"
                     /locus_tag="ACL29Z_001302"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002884573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S21"
                     /protein_id="HGR0069611.1"
                     /translation="MSKTVVRKNESLDDALRRFKRAVTKAGTLQEIRKREFYEKPSVK
                     RKRKSEVARKRKKF"
     gene            complement(14869..15576)
                     /locus_tag="ACL29Z_001303"
     CDS             complement(14869..15576)
                     /locus_tag="ACL29Z_001303"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269928.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucosamine-6-phosphate deaminase"
                     /protein_id="HGR0069612.1"
                     /translation="MKVIKVENQVQGGKVAFEILKEKLANGAQTLGLATGSSPLEFYK
                     EIVESNLDFSNLTSVNLDEYVGLDGDNPQSYRYFMQENLFNQKPFKESFLPRGVKDNA
                     EAEVERYNQILADHPVDLQILGIGRNGHIGFNEPGTPFDSQTHLVELDQSTIEANARF
                     FAKIEDVPTQAISMGIKNILDAKSIILFAYGESKAEAIAGTVSGPVTENLPASSLQNH
                     PDVTIIADAEALSLLEK"
     gene            15727..16755
                     /gene="queA"
                     /locus_tag="ACL29Z_001304"
     CDS             15727..16755
                     /gene="queA"
                     /locus_tag="ACL29Z_001304"
                     /EC_number="2.4.99.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014931869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016740 - transferase activity [Evidence
                     IEA];
                     GO_function: GO:0016853 - isomerase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA preQ1(34) S-adenosylmethionine
                     ribosyltransferase-isomerase QueA"
                     /protein_id="HGR0069613.1"
                     /translation="MNTADFDFHLPEELIAQTPLEKRDASKLLIVNRETGEMQDKHFH
                     SIIDMLEPGDALVMNDTRVLPARLYGQKVETGSHVELLLLKNTSGDEWEVLAKPAKRL
                     KVGTRISFGDGRLSAVVTEELTHGGRIVRFEYQRIFLEVLESLGEMPLPPYIHEKLDD
                     RERYQTVYAKESGSAAAPTAGLHFTKELLAEIQAKGVHLVYLTLHVGLGTFRPVSVDN
                     LDEHEMHSEFYQLSEEAAATLRSVKENGGRVIAVGTTSIRTLETIGSKFDGQIQADSG
                     WTNIFIKPGYEWKVVDAFSTNFHLPKSTLVMLVSAFAGRELVLDAYHHSIQEHYRFFS
                     FGDAMFIY"
     gene            complement(17304..17693)
                     /locus_tag="ACL29Z_001305"
     CDS             complement(17304..17693)
                     /locus_tag="ACL29Z_001305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000240828.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase family
                     protein"
                     /protein_id="HGR0069614.1"
                     /translation="MVKRRIRRGTREPEKVVVPEQSSIPSYPVSVTSNQGTDVAVEPA
                     KAVAPTTGWKQENGMWYFYNTDGSMATGWVQVNGSWYYLNSNGSMKVNQWFQVGGKWY
                     YVNTSGELAVNTSIDGYRVNDNGEWVR"
     gene            complement(17724..18446)
                     /locus_tag="ACL29Z_001306"
                     /pseudo
     CDS             complement(17724..18446)
                     /locus_tag="ACL29Z_001306"
                     /inference="COORDINATES: protein motif:HMM:NF019142.4"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="G5 domain-containing protein"
     gene            complement(19147..19698)
                     /locus_tag="ACL29Z_001307"
     CDS             complement(19147..19698)
                     /locus_tag="ACL29Z_001307"
                     /EC_number="2.3.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000835652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0016746 - acyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HGR0069615.1"
                     /translation="MKSIGTQILQTERLILRRFVESDAEAMFQNWASSAENLTYVTWD
                     PHPDVEITRNSIRNWVASYTNLNYYKWAICLKENPEQVIGDISIVKIDEADLSCEIGY
                     VLGKAYWGHGMMTEALKAVLDFCFTQAGFQKVRARYASLNPASGRVMEKAGMSYLQTI
                     VNGVERKGYLADLIYYGISREEC"
     gene            complement(19945..20769)
                     /gene="nadE"
                     /locus_tag="ACL29Z_001308"
     CDS             complement(19945..20769)
                     /gene="nadE"
                     /locus_tag="ACL29Z_001308"
                     /EC_number="6.3.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000058066.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003952 - NAD+ synthase
                     (glutamine-hydrolyzing) activity [Evidence IEA];
                     GO_function: GO:0004359 - glutaminase activity [Evidence
                     IEA];
                     GO_function: GO:0008795 - NAD+ synthase activity [Evidence
                     IEA];
                     GO_process: GO:0009435 - NAD biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ammonia-dependent NAD(+) synthetase"
                     /protein_id="HGR0069616.1"
                     /translation="MSLQETIIQELGVKPVIDAQEEIRRSIDFLKRYLKKHPFLKTFV
                     LGISGGQDSTLAGRLAQLAMEELRAETGDDSYKFIAVRLPYGVQADEADAQKALAFIQ
                     PDVSLVVNIKESADAMTAAVEATGSPVSDFNKGNIKARCRMIAQYALAGSHSGAVIGT
                     DHAAENITGFFTKFGDGGADILPLYRLNKRQGKQLLQKLGAEPALYEKIPTADLEEDK
                     PGLADEVALGVTYAEIDDYLEGKTISPEAQATIENWWHKGQHKRHLPITVFDDFWE"
     gene            complement(20766..22226)
                     /locus_tag="ACL29Z_001309"
     CDS             complement(20766..22226)
                     /locus_tag="ACL29Z_001309"
                     /EC_number="6.3.4.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004516 - nicotinate
                     phosphoribosyltransferase activity [Evidence IEA];
                     GO_process: GO:0009435 - NAD biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinate phosphoribosyltransferase"
                     /protein_id="HGR0069617.1"
                     /translation="MYPDDSLTLHTDLYQINMMQVYFDQGIHNKKAVFEVYFRQQPFK
                     NGYAVFAGLERIVNYLEDLRFSDSDIAYLESLGYHGAFLDYLRNFKLELTVRSAQEGD
                     LVFANEPIVQVEGPLAQCQLVETALLNIVNYQTLVATKAARIRSVIEDEPLMEFGTRR
                     AQEMDAAIWGTRAAVIGGANGTSNVRAGKLFDIPVLGTHAHALVQVYGNDYEAFKAYA
                     ATHKNCVFLVDTYDTLRIGVPAAIQVARELGDQINFMGVRIDSGDIAYISKKVRQQLD
                     EAGFTEAKIYASNDLDENTILNLKMQKAKIDVWGVGTKLITAYDQPALGAVYKIVAIE
                     DETGQMRNTIKLSNNAEKVSTPGKKQVWRITSREKGKSEGDYITYDGVDISDMTEIKM
                     FHPTYTYIKKTVRNFDAVPLLVDIFKEGILVYNLPSLTDIQDYARKEFDKLWDEYKRV
                     LNPQHYPVDLARDVWQDKMDLIDKMRKEALGEGEEE"
     gene            complement(22342..22830)
                     /locus_tag="ACL29Z_001310"
     CDS             complement(22342..22830)
                     /locus_tag="ACL29Z_001310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000797183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF6773 family protein"
                     /protein_id="HGR0069618.1"
                     /translation="MKNRFYYYQLLDEREEQLFNKAGSESFYICIALSLLSYIISVLA
                     PSLFNSNMLLIVIIIGTFYFFNRARYLGVTYYSRFHFTILGCFFLTLAITALLMLQNY
                     QFNIEIYQHNPLNFKYLSAWVITYIIYLPWIFIGNLGLKSYGEWAQKKFEQDMDELES
                     GE"
     gene            complement(22820..23029)
                     /locus_tag="ACL29Z_001311"
     CDS             complement(22820..23029)
                     /locus_tag="ACL29Z_001311"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013670190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HGR0069619.1"
                     /translation="MAKNLKLKLARVERDLTQGQLAEAVGVTRQTIGLIEAGKYNPSL
                     SLCQSICRCLGKTLDQLFWEEEDEK"
     gene            complement(23414..24142)
                     /locus_tag="ACL29Z_001312"
     CDS             complement(23414..24142)
                     /locus_tag="ACL29Z_001312"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000773447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HGR0069620.1"
                     /translation="MKLNKLNFLKENIRNLYSSGVIYLSLLISFIPPILLTFFILKTQ
                     ETSLGIKHISNFYAMLGMLMAVIHANRVISRDFSHNTVSLFYNQQKNRMIYVLSNFLY
                     AISVSIIYALNGIVLLVIVSKLGIPGDLGLDFIVAIVVNTILLVLFYFLLSYIFYLYK
                     LKSGLVFGILVALLLFIPNILNTMMMNTSNDLFIKAIELLPFYSLPVFVASNTMSISQ
                     YLVVITTIILLYFFTLKKSKKYSF"
     gene            complement(24158..25028)
                     /locus_tag="ACL29Z_001313"
                     /pseudo
     CDS             complement(24158..25028)
                     /locus_tag="ACL29Z_001313"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001220488.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
BASE COUNT         7641 a         5700 c         4513 g         7535 t
ORIGIN      
        1 aacgatatcc aagttacttg tcaagtgttt tttaaatttt tatctcaaaa atattttttc
       61 gttcaaaaaa aggagccatc agttgatttc aagctccttt ttatacagaa ttaaactatt
      121 ttatagttcg acaatcttac ctgtttcaaa gtagacaacc cattcacaga tatttttagc
      181 atagtcaccg atacgctcca agtaggaaat aacttggaaa taatcacgac ccgtaacaat
      241 ggcttctgga tttttcttaa tctcttcagt cgcaaggtca cggatagttt caaaatagtg
      301 gttaatttgc tcatccatgg aggccacccg gtatgcgtcg tcaacagaac cattaagata
      361 aagatcaagt gctgcttcaa caacgctttt aacttcacgt cccatttttt taatttcttc
      421 ctctacagct ggaatgcgct cttccccctt catacggatg gttgcctggg caatggctac
      481 agcgtgatcc cccatacgct ccacatctga tacagcctta aggacagtca agactgtacg
      541 caaatcttga gagactggtt gttggagtgc gatcatttca aatgatttct tttccagttt
      601 cacttcgtat tcatttactt ctgcatcatc ttcgatgacc tcttttgcca ggtcacggtc
      661 atgcgtgaca aaagcacgta ccgtacgatt gatttgtgag agcacttctt gtcccatagc
      721 gtagaactgg ttatgtaatt tctctaaatc ttcttcaaat tgagatcgta acatctttca
      781 tctccttatc caaattttcc tgtaatatag tcttccgttt ccttgtgttg gggatcaagg
      841 aacatctgct tggtatcatt aaattcaatc aaatctccat ctaggaaaaa tcctgtctta
      901 tcagagatac gtgaagcttg ctgcatggaa cgggttacca gaagcatggt gtacttgtct
      961 tttagaccat acaaggtttc ctcaatttta ccagctgaaa tcggatccaa agccgaagtt
     1021 ggctcatcca agaggatgat tttaggacta gttgccaaga cacgggccac gcagacacgc
     1081 tgctgttgac cacctgacaa tccaatagct gaatcatata gacgatcctt gacctcatcc
     1141 cagatagagg caccttgcaa ggctttttct acggcttcat ccagaacctg cttatcctta
     1201 attccattga tacgaagccc gtagacaaca ttctcataga tagtcatagg gaaaggatta
     1261 ggttgttgga aaaccattcc gatttcctta cgtaattcaa ccgtatctgt acgcggactg
     1321 tagatgttgt gaccattgta caccacggat ccagttgtgg tcacctctgg attgagatct
     1381 cccatgcggt tgagagactt gaggagggtt gacttccctg atccagatgg accaatcaag
     1441 gctgtaattt ccttaggttg gaaagatagg gaaacactat tcaaagcctt ctttttatta
     1501 taataaacgg acaggtctga tacctgtaaa atcgcatctg tcatacggtt tcctttctaa
     1561 ccaaagtgac cagatacata gtcattggtg gactgtagct tggcattttg gaaaatagtt
     1621 gcagtcttgt catactcaat caaatcaccc aagtaaaaga agcctgtata gtcacttgca
     1681 cgagcagcct gctgcatatt atgcgttaca atgatgatgg taaagttttt cttgagctca
     1741 aacatggtct cttctagttg catggtcgca atcggatcca aggctgaggc tggctcatcc
     1801 attaagagga tatctggctt aacagagatg gcacgagcga tacagagacg ttgttgctga
     1861 ccacctgata aggtcaaggc tgacttgtgg agatcgtctt taacctgatc ccagagggca
     1921 gcctgacgaa gggaggtttc tacgatttca tctaggactt gcttatcctt aactccagca
     1981 cgttcatgcg caaaggtaat attacggtaa attgacttag caaatggatt ggggcgttga
     2041 aaaaccattc caatgtgttt acgcatttca taaacgttga tttctggacg gttgacatca
     2101 attccacgat agagaatctg cccagttact ttagcaatat caatagtatc attcatgcga
     2161 ttgagactgc gtaagtaggt agatttcccc gatcccgacg gaccaatcaa agctgtaatt
     2221 ttatttcttt caaattgcat atcaatcccc ttaatggatt catttttacc atagtaaaca
     2281 tggacatcct tagtagaaag ggctactttt tcttcaggaa aggtaaggat atgcttctca
     2341 tcccagttat atgttgacat ggcttctcct ttaggcagcg gttaatttct tgtgtagata
     2401 gcttccgaac ttacgagctc caaagttaaa aatcaggata aagatcagga gcacagcggc
     2461 agaacctgct gatacaatgg ttccatctgg aatagtgcct tcactattga ctttccagat
     2521 atggacagcc aaggtttctg cttgacggaa gatagagatg gggctagtca cactgaggat
     2581 attccagtta gaccagtcaa gagctggcgc cgattgccct gctgtataga tcagagctgc
     2641 agcttcgcca aagatacgac cagatgccaa gacgacaccc gttacaatac ctggaagcgc
     2701 ttctggaata acaacatgaa ccactgtctc ccagcgagaa atcccaagag ccagaccagc
     2761 ctcacgttgg gtatggtgaa cgtgtttcaa actatcctct acattacgcg tcatctgagg
     2821 caagttaaag actgtcaagg ccaaggcacc tgaaatgatt gaaaatccat actcaaactg
     2881 gactacaaag atcaagtaac caaagagacc caccaccact gatggtaaag aggacaagat
     2941 ttcaatacaa gtccgcacaa agttggtaac aggacctttt ttagcatatt cagccaagta
     3001 aatcccagct cccatagaaa gaggtacaga aataatcaag gtaatgacca ataggaaaaa
     3061 ggaattgtaa agctgaatgc caatcccacc acctgcttga aaagcagaag accttccagt
     3121 caagaaagac caagagatat ggggcaagcc ccgaaccaag atatagagaa tcaaggaagc
     3181 caagattgtc acaatgatgc tagcaatcgt atagaggaca gctgttgcaa gtttatctaa
     3241 tttcttagcg cgcataattt ttctttcctc tttctttcgt aatcaattta atcacactgt
     3301 taaaaactaa actcatcaag agcagtacca aggccagtga ccagagaaca ttattattta
     3361 cagttcccat gacagtgttc ccaattccca tagttaatat agaagttaaa gttgcagctg
     3421 gtgtggtcaa ggaagttggg ataacagctg agtttccgac aaccatctgg atagctaaag
     3481 cctcaccaaa ggcacgcgcc atcccaaaga ccactgcagt gaaaatacca gaacgggccg
     3541 ccttcaagat cacacgccag atagtctgcc agcgagtggc tcccatagcg aaactggctt
     3601 cacgataata acgaggaacc gcacgcaagc tatccgttgt cataaaggtt acggtcggca
     3661 aaatcatgac aaagaggacg gaaatccctg acaaaatccc aaaaccagtc ccaccaaaga
     3721 cactgcgaac aaagggaacg acgacttgca agccaataaa tccgtacact actgaaggaa
     3781 tcccaaccag gagttcaata gctggttgca aaatcttcgc cccttttggt gatacttcgg
     3841 tcataaaaac tgctgcacca atagcaaagg gtgttgcgat aagggctgag agaatggtaa
     3901 cgataaagga acccaaaatc ataggaaggg caccaaattc tttactagaa ggattccaag
     3961 ttcctcccaa aagaaagtca aagatattca caccattgac aaagaaggtc gacaagcctt
     4021 tttgcgctac gaaaaccaaa atcatggcca caaggatgac tatcaaagaa agacaggcaa
     4081 aggtcaaacc ttttcctaat ttctccagac gagaattctt tgatggaagc aacattttct
     4141 tagctaattc ttcttgattc attattgtct cccttccaac actgtcacag ttccggcagc
     4201 atctttttca accttcattt ccttaatcgg aatatacttc aatcctttga caatcccttc
     4261 ttgggtctca tccgagagaa caaaattgag aaattctgca gccaactcat tgggctgccc
     4321 caatgtatac atatgctcat aagaccacaa gggccaatta ttgctactta tattttctgg
     4381 acttaagtca tagccattca acttcatgct tttgaccgaa tcatctatat aggtaagaga
     4441 taaataagag atagctcctg gactttttga tacgattgat tttaccgctc catttgaatc
     4501 ctgctcctga ctttgcatgg cagactgacc ttccataatg acagtatcaa aggtagcacg
     4561 agagccagag ccggctgccc gattgataac agagatgggt aagtccttac caccaacctc
     4621 tttccaattg gttacctcac ctatgaagat ttgacgaagt tgctctgtcg ttaggttatc
     4681 aacatcaacc tccttattga caatcagagc caagccagct accgcgacct tgtggtcaac
     4741 aagagcagaa gcatcaattc cgtctttttc ctcagcaaat acatctgagt ttcctatatc
     4801 aactgcccca gactgaacct gggacaagcc tgtaccagaa cctccccctt ggacattgac
     4861 cgtttttcca acatgaatcg tgccaaattc atctgccgct acttcaacca agggttgcaa
     4921 ggcagttgag ccaacagccg ttatggattc tccacgatca atccagctag cacagcctac
     4981 taaacaagcc gtcagccaaa aagcgataag agacagagca agcttttttc tttttttcac
     5041 tgtttttctc ctcgaaaata attatgaata ctgtgaattt tttaagtagt tctttatgag
     5101 ttgacgcatg aattcttacc aaatttctgc gcaattgatt atttatataa tataggctat
     5161 attactcttt cctaacctcc ttttttcata tgtggataaa atctcttgtc tatcccttcc
     5221 cccattgtca cccattataa tcatttcgtg tctctttttc ccctttttaa tgcaagggaa
     5281 attactctcc tcagatgata atccaaaagc tagaaaggta tctcaaacct ctctactctc
     5341 ccagactagt ttacaactaa aaggaaaaga ttctatttta tgagaaatct agtttacaag
     5401 cggtaagaac gctaataact aaacttcttg tactctttga aaatctcttc aaaccagtgt
     5461 tttgagctat ctatggctag cttcctagtt tgctctttga ttttcatcga gtagtaaaac
     5521 tacatgtgat ggcaatcaag atatcaagaa tcatcctact aaaaaaatcc atactttcac
     5581 tataacatag aataagatat ttgactagca ttttcatttg aatctgaggc cttttggaaa
     5641 ataatttttc aaaacatttc cagtaacctt tgcaaagccc aagccattgc ctttaaccaa
     5701 aacttggtac caaccatttg gcagactttc tgccagctga acggtttctc cagccgcata
     5761 cttgacaaac gcttcttggc caatttcaac cgactgttcg acctgactcg gtttcaaggc
     5821 taaaccaaga gcgaaactgg gctcaaagcg tttcttctta aaagtgccca gatgcagtcc
     5881 attgcgagca atcttgagct tccctaaatc tggcaaaagt tctggcaaga gataaagctg
     5941 gtctccaaaa gtctgcaaga tacccggtag attgaccttc aaatggtttt gggcaaattc
     6001 ctgccacaag gcaacttgtt cacggctgag gttactctta cttgccttaa atttaggagc
     6061 tggattgtta cccttaaact gtagatgggc aacaaactga ccctctccct taaactgatg
     6121 agggtacatc cgagccgttt ctggcaggtc aataccagct accattccat tgatatgctc
     6181 tactggcaac aagtcaaaat catactcttc cagcaaccaa ttgacaatct cttcgttttc
     6241 ctcgggtgcc caggtacagg tcgaataaac cagacgacca ccttcagcta acatggtcac
     6301 tgcatcctcc agaatttctc tttgcaagct agcacattga ctcggataat ctaagctcca
     6361 atagtccata gcatcaggtt gcttacgaaa cattccttca ccagagcaag gggcatcaag
     6421 aacgattaag tcaaaatagc ctttaaagac cttgaccaag cggtcggcag attcattggt
     6481 caccacgaca tttgtcgctc caaaacgctc catgttttca accaaaatct tagcccgttt
     6541 gcttgaaatt tcattggaaa caagtagccc ctcacctgct agataggctg ccagttgagt
     6601 tgatttgccc cccggtgcag cagccaagtc caagaccttc ataccaggac tgggttgggc
     6661 tacttgagcc accatttgag cagcaggttc ttgcgaataa actaaacctg tagcatgctc
     6721 aggcgatttc cctgaaacct tcccatagtg gccccaaggg gtttgagtaa tggcatcaga
     6781 aaaggaaagt tgctcttctt ttaagggatt gacccgaaag gccgaaaccg cttcctcctc
     6841 aaaagaggca agaaaatctc ttgcctcatc tcctagtatc tctttatatt tttcaacaaa
     6901 tccttctgga aattgcattt aagttctttt cctttcgtaa atataggact gaatttcctc
     6961 ctgcatctca agaggcacca tcatgaccgg ctgtctggtt tgaaaatcag gagcttcacc
     7021 aaaaagggtc acaacccgat agcccagact ttcccctaaa atactagctg cggcataatc
     7081 ccatggttgc agataagtga gataggtcaa caaacgccct gacaaaatct tggcaaaact
     7141 aatggccgca cttccataga cacgaacacc aagaaccgat cggctcaaat cagccagccc
     7201 ccattcattg gtttccagca taccactatt ccctgcaatg agaaaatctc caagtggttt
     7261 agttttaaaa ggagctaggg gcctatcatt tagacaaact ggaaattccc caccaccgtg
     7321 gtaacaatcc cctttgacca catcataaat cagaccaaac tgtccctgac cattttcaaa
     7381 ataagccatc ataacagcaa aatcttcctg ctgggctaca aaattattgg taccatcaat
     7441 gggatcaatg acccaaacct tgccctcttg aaccgaggct cgcagacaac cttcttcagc
     7501 acaaatctta tcctcaggat aacgggacaa aatctcacca accaagagtt cctgaacttc
     7561 tttgtccagt ctggtcacca aatctgttga agaggacttg gtttcaacac gcaagtcttc
     7621 ctgcatatgg tcaagaatgt actggcctgc tttcttaaca agctctttag caaattcaaa
     7681 tttactttcc aagagaaatc tttccttccc ctttttcttt ggcagcctga actgctcggt
     7741 aaagtgaata gccactaacc gtttcaaatt ctcgtcccaa acgtttctct tcgctcttgc
     7801 ttggcacgac cgctttgaat cccttatagg agtccagtaa ctttttagcc tctactttgc
     7861 cttcataggc agcttcaaca tcattaaaaa aagaaagcac tgaagcaagt tcttcagtgc
     7921 tccacgacaa atctagtggg taactatact gtttgttcat taactaatac cagctctcat
     7981 tcttgcttct tttagttctt gcttacgata actacgaggg agaaaagcac gaatctcatc
     8041 ttcattaaaa ccgatttgca tacgcttggc atcaataata attggacgac gcaaaagact
     8101 aggatactgc tcaatcaaat gaagcaattc cgataccgaa atactctcta catcaatatt
     8161 caatttttga aaaatttttg aacgagttga aatgatgtca tcagtaccat tttcggtcaa
     8221 ggaaaggatg tgttgcaatt cttttcttgt taaaggactg gtcataatat tgtgttccac
     8281 aaagggaacc ttatgttttt ctaaccaggc cttagcctta cgacatgatg tacagctcgg
     8341 tgatagaaat agtgtaatca tgcttttctc ttcttatcta tactttgcta cttctattat
     8401 acaaaaaaat aaggcgcttg actagggatt tttagaaaaa aagcctattt tttcaagaaa
     8461 aataggctgt ttgcgaacga ttgacacaat tggatttggt taattcactc ttaacgatgg
     8521 ttttaaacga tatatatttt tatatatgca aattaaaaac atctttcatt tcacttccta
     8581 cgacttttca gacacagata cccaaagaag ctttcataga gggcaaaaaa gaggaggaag
     8641 gcatgaagaa agaaggtctc tggcaaaatc ataataacag gatccttggc tggatcaaaa
     8701 agccaggtat catctcccac aaagagaatt tgatggaaaa gagtaaagaa ttggtcaaaa
     8761 ccaatcaaaa ctcccccaag tccaatcatc acaggtaaga ctactagagt caggagactt
     8821 tttcgataaa gagacaaaaa gtcctttttc acaatcctat tgacaaagac atagaaactt
     8881 ggcagtgtca ctagagctac tagctgaacc aaatgaaaga gattcttgac cactgcgaaa
     8941 tggtgcagac cagctgctga cgaacgaaaa tcaggcatct gtaagacctg actaaaagga
     9001 ttggtcagat aattcatcaa gatatgaaaa ttgtattgaa tggtttctgg ttttagatag
     9061 actcgattcg ttaagtttag ccactgaatc tccataggat agaaaatcca agccagataa
     9121 atggtcagaa ggattgagag ggagaggaga aagagcatag agccccaaaa ggtcaattta
     9181 gttttcatca aaatcccact ccgcaaggct agaaaccaca tgtgtcggtg cgattggcag
     9241 gccagctact tcttctgcct tggtaaaacc tgtcgtcacc aagagtgttg gaatgccatt
     9301 gtcaatccca gcccggatat cagtcaaata attgtcccca accatgatta actcttcacg
     9361 ttccaaacct aagtgctcaa ccgccttgtc cataatgatg gcatttggtt ttccgatata
     9421 aaccggcttc actcgtgtcg ctacttcaag cagcgtaatc agtgagccag cacctggcaa
     9481 aagaccacgt tccgtcggga tgttgaggtc aggattggtt ccgataaaat gggcaccctt
     9541 ttgaatagca agagttgctg tggcaaattt ttcatagtcg acttgccaat ccagaccaac
     9601 taccacgtag gcagggtttt ccttgtcttc cacataacca gccgccttga tggcttcctt
     9661 gagtcctgct tctccgacga catagacggt cttttcaagc cccaaatcat tcatatagtc
     9721 gatggttgcc aaagtcgctg tgtagacagt cgatagaggc gtatcgatat taaaattctg
     9781 agccaacatc tccttaacac tctctggagt gcgggttgta ttgttggtta caaagagata
     9841 gggaatgtcc cgcttttgca attcatgaac aaaagtctct ccagcaggga ttcggtcttt
     9901 ccccttataa atggttccgt ctaaatcgat taaatagcct ttatatttca tctatttctc
     9961 cctaaacctt ttttatttct tgccaagtaa tgattgcttg ggcattgata accccatcac
    10021 ttgtaatttc atgcttgctt tccagtccag tccgttcaac agccgatgta atcaccccac
    10081 ctggtcgaac ttccttgaca tacttgaggt tgattttctt gggaatatag tgggtcaaaa
    10141 aatccgctcc catgacctca aaaatccagt ccaagtattt actgttattg acatgaccat
    10201 tcatatccaa gtcgtaaaaa cgaacatggt aatccttgct gatcggctct tccaaggatt
    10261 catacttcgg tccacggata agttttttat caaaatcaga ctggtaagga gccacaatct
    10321 caggttcaac agcatggact tttcgactgt cgcggtccat gagaacaaag gtcgccatca
    10381 tatggatgag ctcctgcccc gcttcattat aaatagtaaa gcgacggtag caaaaaagtc
    10441 gattgtagct caaggcttcc gtttcgatgg taatttcttc cgcaaaacga ggcaaacgaa
    10501 ccacctcaat atcatattct gcgataatcc agaccagatt atagtcttcc aaaatggcct
    10561 tatcactaac tcccagttca atcgattgca tccctgaaac ttgcagtgac agcaaaatca
    10621 catctggaag tttgatatga ccgttcatat cagccatatc aaaaggaatt ttcattttca
    10681 tttgataagt taagcccatg atcctactcc aaaataaatc gttctgctac agtatctccc
    10741 aaaaagagac ctctctttgt catgcgaacg tggtcaccct caatctgcat gaggccttgt
    10801 tgaaccaaat ctctgacaat ttctccataa agtccagcaa aagactgtcc aaatttttcc
    10861 tcaaatcgcg ccatggaaac cccggatttc ttgcggagtc ccaagaacat ttcttcttcc
    10921 atttgctcct tttgactcag gtgatcttct gtaatacaag cattgccttc ctcaaccgca
    10981 ctgagataat gacgaatggg accatgattt ttatagcgta ctccattgac ataaccagat
    11041 gcccctgcac caataccata gtattcagca ttgtcccagt acatgagatt atgacgactt
    11101 tcaaaaccgg gtttggagaa attagaaatc tcataatgct caaaacccgc tcgctccagc
    11161 tctgcaatga tgtactcaaa catctccgct tctagttcct ccttaggcag aggcaatttc
    11221 ccacgtcgca tccggttcat aaagaccgta tggttttcta aaatcaaact atacaaactc
    11281 atgtggggaa tatccaatcc aatggcttta gccacatttt cctttacttg ctccatggtc
    11341 tgaccaggca gagcataaat caaatcaatg gagatgttgt caaaaccagc cagtttcagg
    11401 cgatcgatat tttcataaat atccttctcc aaatgactgc gcccaatctt tttcaacatc
    11461 ttatcatcaa aggtctggac acctagcgaa acacgattga cagccgaatt tttcaaaaca
    11521 gctatcttat ccgcatccaa atcgcctgga ttggcttcaa tggtcaactc ttccaagaca
    11581 gacaaatcca agtttttagt caagccattc agtaacacct ccagttgcgg agccgacagg
    11641 gctgtcggtg ttccaccacc gatataaagg gttgacaact tttcaatatc ataagaacga
    11701 aactcttcca gcagatgctc taaatagctg tcgactggct gatttttgat gaagaccttt
    11761 gaaaaatcac aataataaca aatctgggta caaaatggga tgtgcacata ggctgacgtt
    11821 ggttttttct gcatagtaat tattatacca caaagactag attccagata aaaatcacca
    11881 tccccagata catagtccgt ccggagatgg tgatggttta ttcttctgtt atatgaatca
    11941 caatctcttc tgagtcatca agagcttcgg ctttttcttg ccattgttcc ttgagattat
    12001 ttaattgatt ttttgatgct tctgtcgctt gaaaagcata ggatttagct tgagcaagta
    12061 tactgtccac agtgatttca cctgactcaa cctgttcttt tgttttcaga acaaaatctg
    12121 tagcctgctc cttaacttct gtcagttttt cacagacttg ctccttggca tactccggat
    12181 cttctctcaa atcatctaga aaatcttgag cctgactgca aacttgtttg cccttatcac
    12241 ttgttaaaaa caaggcaaga gctgcacctg aaaccgttcc taaaaggatt gaggataatt
    12301 tacccataag gattctcctt ttttattttt tgaaaaattt acttgcaaga cgaagagctg
    12361 acagacttgc accagtcttg agtgtttttg aaccagctga tgaagctttc ttgctcaaga
    12421 cacgcgcatg gtcattgagg tctgaaacag atagagataa atctgcaaca gcactgaaga
    12481 gtggatcaat cgtagccacc ttgacattga tatcatctgc caagacattg accttagcca
    12541 acaactcatt ggtgtgatgc aaggtcacat ccacatctga agtcaaggtt ttaatcgcct
    12601 tttctgtttc atcgatgaca cgaccaagct tttgtacagt aatgatcaga tagaccaaaa
    12661 agacaatcaa agctagggca acaagaatat atgcaacttc taacatttag ttttcctcct
    12721 ctgtaatata gtaaggggcc ttctttcgat tttgataaat aacgatcatt ataccgagac
    12781 cgataaggac aactgacagc cattgggaca ctcgaagtcc gaagaacatg agactatctg
    12841 ttcgcatacc ttcgatgacc atacgaccga aaccatacca aatcaagtaa aaggccgtga
    12901 tatgacctcg tctgagactc ttccatttcc gtctaaaaat cagaatcaag gcaaagccaa
    12961 gcagattcca tagagactca taaaggaaag tcggttgacg gtagctcccc tcaatataca
    13021 tctggtcacg gataaagcca ggtagataat ccagattatc cactgttgca ccataagctt
    13081 cttggttaaa gaaattaccc caacgcccca aactttgagc aatcataacg ctaggcgccg
    13141 caatatctag aaaatcccaa gtattgatga gtttacggtc agcaaagata tagagcacaa
    13201 gagccccagt tatcaaacca ccgtaaatgg ccaaaccacc attccaaatg gcaaaaatct
    13261 ctcctaaatt ctgactatag taatcaaatc ggaaaataac atagtagaga cgagctccta
    13321 aaatagccaa gggaaaggct actaagataa aatctaaaat atcgtctggt atgatcttct
    13381 ttctaggtgc ttctttcatg gtcaaataaa ccgcaagaat caagcctgtc acaatacata
    13441 aggcatacca acgaatggct aggggtccta gttgaatagc aattggatca agcattttgc
    13501 acctcatttc gagcgatgag acttgtcagt cgttcgtcga acaaacgggt cgcatcaaag
    13561 cccatttcct tggcacgata attcatggca gctgcctcaa tcacaacaga gatattacga
    13621 cctgttttaa ctggaatacg aatacgagga atggctacgc cagaaacttc aagttcctct
    13681 gcattgtttc caagacgatc aaaggtctta tgcgtatcgt aattttccaa atagacagca
    13741 agctgaacct gtgaagaatc cttgacagca ctcgcaccgt agagactcat aacatcgata
    13801 ataccaaccc cacgaatttc aatcaagtgt ttcaaaattt cagctggttc accccagaga
    13861 gtaatctcat ccttggcaaa gatatcgaca cggtcatcgg ctaccaaacg gtgaccacgt
    13921 ttgacaagct caagacctgt ctcactctta ccaattccac tatctccctg aatcaagacg
    13981 cccatcccat aaatatccat caagacaccg tgcacactgg tacgttctgc caaacgagaa
    14041 tccagatagc tagataactc tccagataaa cgactggtag ctgcacggct ggttaaaata
    14101 gcaatcttac attctctagc agcctttaac atctcctctg gaaccaccaa accacgggca
    14161 acaatgactg ctggtgtctc aggtagaaac atttttttca aaacttcata acggctgttg
    14221 gaaggcatgc tgatcagata agaccactcc ttcatcccca aaagttgaat ccgctctggt
    14281 gtatagtagt caaaatagcc tgtcatttca agaccaggtc gcgtaatatc cgctatattg
    14341 atttcctttt caagcaattc tggttcacca tagacaatgt ctagtctaag cttttcaatc
    14401 acttctttta ctaaaaccga catcatttcc tccttcaaat gagttcttct ctctattata
    14461 tcaaattgta ggaggaagtt tcagattttt gcaggctttg gagtatttat ttaaaagaaa
    14521 aaggactaga tttctctagc ctttcatttc aattagaatt ttttacgttt acgagctact
    14581 tctgatttac gtttacgttt tacagaaggt ttttcataga attcacgttt gcgtatttct
    14641 tgaagagtac cagctttagt aaccgcacgt ttgaaacggc gaagtgcgtc gtcaagagat
    14701 tcattcttac gtactactgt tttagacatt tttttcactc ccttcaagtt caatatctat
    14761 ttcattctac acgtaaaagg aataattgtc aagcaaaaat gcggtttaat tttgattttt
    14821 tcttccattt atacaagagt tgaaagcgtt caatagaaca ttgctttttt atttttcgag
    14881 taagctaagc gcttcagcat ctgcgatgat ggttacatca gggtgatttt ggaggctact
    14941 tgcaggtagg ttctcagtca ctgggccaga tactgttccg gcaatggctt ctgctttcga
    15001 ctcaccgtaa gcaaaaagaa taatagactt ggcatccaaa atgtttttaa tccccattga
    15061 aatagcttgg gttgggacgt cttcaatctt ggcaaagaag cgtgcattgg cttcgatagt
    15121 agactggtca agttctacta gatgcgtttg actgtcaaat ggagtaccag gctcattaaa
    15181 gccgatatgc ccattgcgac cgattcccaa gatttggagg tcaactggat ggtcagccaa
    15241 aatttggttg tagcgttcaa cttcagcttc agcattgtcc ttaacaccac gaggcaagaa
    15301 actttcttta aatggttttt ggttgaacaa gttttcttgc atgaagtaac gataagactg
    15361 tggattgtcc ccatcaaggc ccacatactc atcaaggttg acactggtta gatttgaaaa
    15421 atcaaggtta ctctcaacaa tttccttgta aaattcaagt gggctacttc ctgtcgcaag
    15481 tcctagagtt tgagctccat tagccaattt ttccttcaaa atctcaaaag caacttttcc
    15541 accttgaact tggttttcaa ctttaataac tttcatcttt tcatcctcca tttctgtcta
    15601 tatttattat atggtataga ccaatttttg tcaagtgaaa acgatttaat ttctaaaaaa
    15661 agagcgtcca aacttgaaac gtgttataat ggataggatt agaacttaga aagaatgaac
    15721 agatatatga atacagctga ttttgatttc cacttgccag aggaattgat tgcccaaacg
    15781 ccccttgaaa aacgtgatgc ctccaaactc ctcatcgtca accgtgagac aggagaaatg
    15841 caagataaac acttccactc tattattgat atgctggaac ctggtgatgc ccttgtcatg
    15901 aacgacaccc gagttctccc tgcccgcctc tatggtcaaa aagtggagac aggaagtcat
    15961 gtggaacttc tcctccttaa gaacactagt ggagacgagt gggaagttct ggctaaacct
    16021 gccaaacgcc tcaaggtcgg tactcgtatc agctttggtg atggccgcct cagcgctgtc
    16081 gttacagaag aattgaccca cgggggacgc attgtccgct ttgaatacca aagaattttc
    16141 ctagaagtct tggaaagtct gggagaaatg cctctgccac cttatatcca cgaaaaatta
    16201 gatgaccgtg aacgttatca aaccgtctac gccaaggaaa gcggctctgc tgcagcaccg
    16261 actgctggtc ttcacttcac caaagaactg ctggcagaaa tccaagctaa gggtgtccat
    16321 ctagtctatc tgactctcca tgtcggactc ggaaccttta gacctgtttc tgtggataat
    16381 ctggacgaac acgaaatgca ctcagagttc tatcaacttt ctgaggaagc tgcggccacc
    16441 cttcgctctg tcaaagaaaa tggtggtcgt gtcatcgctg tcggaaccac ttctatccgt
    16501 accttggaaa ctattggttc caagtttgat gggcaaatcc aagcagattc tggttggacc
    16561 aatatcttta tcaaacctgg gtatgagtgg aaggtcgtgg atgccttctc aaccaacttc
    16621 cacctgccaa aatcaactct ggtcatgttg gtttctgcct ttgcaggccg tgaattagtc
    16681 ttagatgcct accaccattc catccaagaa cactaccgct tcttcagttt tggtgacgcc
    16741 atgtttattt attgagaaag aatttctcta aatcttctaa taccaataaa tcgctaagat
    16801 attatttcaa agaacatcta caattgaaac tctagctagc tgtagaagac gcctagtaca
    16861 ttgaaattaa aatgcaagac acatgagtag caccatattt gttgctctta tctgtcctcg
    16921 caagagacta ttatgagtta tttcagaatc attcactact ttgaccctga ctctccttag
    16981 tctcaaaatc aaagacttat actcttcaaa aatctcttca aaccgcgtca acgtcatctt
    17041 ggattatata tgtgactgac ttcgtcagtt ctatctacaa cctcaaagca gtactttgag
    17101 caacctgcga ctagttttct agtttgctct ttgattttca ttgagtatta aacaaaaagt
    17161 gaacaaagct gaattctaat gtacagaaga ctaggcttgt tcactttttt atagtcgcta
    17221 taagatgacc ttatctatag ctttttatat ataattatat attcagacat actattatca
    17281 attttgtcgc agggaggaat ctgttaacgc acccattcac cattatcatt gactctatag
    17341 ccatctatac ttgtattgac cgctaactca cccgatgtat ttacataata ccatttacca
    17401 ccaacttgga accattgatt gactttcata gaaccgttgc tgttgaggta gtaccatgaa
    17461 ccattaactt gtacccaacc tgttgccatg gaaccatcag tattataaaa ataccacata
    17521 ccattttctt gtttccagcc tgttgttgga gcaactgctt tagctggttc tactgctaca
    17581 tctgttcctt ggttagatgt aacagataca ggatacgaag gaatagatga ttgctcagga
    17641 acaacaactt tttcaggttc tctcgtccct ctccttatac gtctttttac catctcttta
    17701 gtaatttgac gagaagtagt ttcttcaatt gttccatcac gttcatctac agcatagatt
    17761 gtagtaagag taattttacc aatttctcct acttcttgac ctttatcaag agttgggtca
    17821 tcgagatatt ctgtttcgat tggaatttct tggacaagaa cttggggctt ggttcctttt
    17881 ttaacaactc ttgtttgaga gtcttctttt tgacttaaag tactctcagt tacttgtcca
    17941 ctctttccat ctacatcata agttatcgtt gtaactgttt tcccattctt tcctagagta
    18001 atctcttgct cctgtcctgc agaaaggtca ttgtctgctt catatttagt agtaaatgga
    18061 acaagaactt cttcaacctt gcttttagct ggaactttga taactgtatc cgtgacttct
    18121 tttctatcaa cagtaacctt ttcggtaaca tgaccagtct ctggattaac atcgtaggtc
    18181 cttgtcgtag ttacatagcc atcctctcca tcaattgtaa caggattttc actacggtct
    18241 tttgtttcat ctttttcata acgaattcgc gtacttgaaa ttttcttggt tactacctta
    18301 ggtttagtcg ctacttttac aataatactc ccattgtcag cgtcatcata ctctattccc
    18361 tcttctttat ctctagtatc atctctgaca tattgaatcc catcagcagc atgaacaaaa
    18421 cttgtattca gattcctcct aaaaataaag ttagcccgat taccgcagaa ccaaaaatct
    18481 ttccgagttt acgtaatgca tagcgcttat tagtattaga ttttgccatt acatcctact
    18541 tctagtatag catcttttct atcaaacgtt aaacagtata ctttatatat caaatagact
    18601 tagaatgata tattgattat tgaactaaca ctttaactat atcgtaatca atctcatata
    18661 taaaggattg cagacatctt atctaaatac atgctaatat atttagatac aaacattcca
    18721 acttgataat tttcactcat ctttcatcat tccttataca actatgcagt ataaatagaa
    18781 tagttttctc atcagaatga gactatttta atattagata atttgataga aaaaaacata
    18841 aataaaattg gttgaattta attccctaac tcgatagaag attctatttt aaatttaaca
    18901 acagctagga ttacactata aaaagcacat taccacctgt tcgactggag aatctagtcg
    18961 attagctccc tcttagttac aagcttaaag cgatttttta actaatacta aaccagatta
    19021 aagaaggaac tagaacatct gtcttgtact aatcaatatg ctattttaaa attgcaaata
    19081 aacttggaat gctaattatt atatttacaa taaatagttg acttcgatag aaacagaaaa
    19141 tagaattcaa cattcttccc tacttatacc ataataaata agatccgcaa gatagccttt
    19201 tctctctaca ccattaacaa tggtttgtag ataggacatt ccagcctttt ccatgacacg
    19261 acctgaagct gggttgagac tggcataacg tgctctgacc ttttgaaaac ctgcttgagt
    19321 aaaacaaaag tccaagacag ctttcaaggc ctctgtcatc ataccatgtc cccagtaagc
    19381 cttgcctagc acatagccga tttcacagct taaatcagcc tcgtctatct taacgatgct
    19441 gatatctcct atcacttgct ctgggttttc ttttagacaa atggcccatt tataatagtt
    19501 gagattagta taggaagcaa cccaattgcg aatcgagttt cgagtgattt cgacatcagg
    19561 atggggatcc caggtaacat aggtcagatt ctcagcggat gaagcccaat tttgaaacat
    19621 ggcttctgca tcactctcca caaatcttct taaaatcaaa cgttctgtct gtaatatttg
    19681 cgtaccgata gatttcatga tgctacctca cttccttatt tctatgctcg tagtaaaaag
    19741 actcaactca gtaacagcta gaaaacgagt ttgtcttcta atttcttgac gcagttgctg
    19801 catggtttga aatgcgctct agcaatcttt ttcaaaccta gtcatcgttg caggggtaag
    19861 acgatgaaat cgaactcttc gagttaccga atctgcctca ttttcttatt tctaaactcg
    19921 gggttcaaga tcccccggac ctttttactc ccaaaagtca tcaaatacgg tgatgggtaa
    19981 gtggcgtttg tgttggcctt tgtgccacca gttttcaatg gtcgcttgag cttctgggct
    20041 gattgttttg ccttctaggt aatcgtcaat ctctgcatag gtgactccaa gtgcgacttc
    20101 gtcagctagg cctggtttgt cttcttctag gtctgccgtt gggatttttt cataaagggc
    20161 tggctctgcg ccaagtttct gcaagagttg ttttccttgg cgtttattga ggcggtaaag
    20221 agggagaata tccgcaccgc cgtcaccaaa cttggtaaag aaacctgtga tattttccgc
    20281 ggcgtggtct gttccaatga ccgctccgct atgggaacca gcaagggcat actgagcaat
    20341 catacggcaa cgtgccttga tattcccctt gttgaagtct gaaacaggac tacctgtcgc
    20401 ttcaactgca gctgtcatgg catcagctga ttccttgata ttcacaacca agctgacatc
    20461 tggctggatg aaggctaggg ctttttgagc atctgcttca tcagcttgca ctccgtatgg
    20521 caggcggaca gcgataaatt tgtagctatc gtctcccgtt tcagctcgca gttcttccat
    20581 agctaattgc gccaaacgtc ctgccaaggt tgaatcttgt cccccagaaa tccctagtac
    20641 aaaggttttt aggaagggat gttttttcag atatcttttt aagaaatcaa tagaacgacg
    20701 gatttcttcc tgggcatcaa tcactggttt gacacccagc tcttggataa tcgtttcttg
    20761 caaactcatt cttcttctcc ttcaccaagg gcttccttgc gcatcttatc aatcaagtcc
    20821 atcttatctt gccatacatc acgcgccaaa tccactggat agtgctgcgg attgagcaca
    20881 cgcttatact catcccacaa cttgtcaaat tccttacggg cataatcctg aatgtcagtc
    20941 aaactaggca agttgtaaac taatatacct tctttgaaga tatccaccaa gagaggaacg
    21001 gcatcaaaat tacgaaccgt cttcttgatg tatgtatagg tcggatggaa catcttgatt
    21061 tctgtcatgt cgctaatatc cacaccatca taagtgatgt agtcaccttc tgacttgcct
    21121 ttttcacgac tggtaatgcg ccacacctgc ttcttacctg gcgtcgacac tttttccgca
    21181 ttattagaca gcttaatcgt attgcgcatc tgaccagttt catcttcgat tgcaacaatc
    21241 ttgtaaaccg ccccaagagc tggctggtca taggctgtaa tcagcttggt acccacgccc
    21301 cagacatcaa tcttggcctt ttgcatcttg aggttgagga tagtattttc gtccaaatca
    21361 ttagaagcat aaatcttagc ctctgtaaat ccagcctcgt ccagttgctg acggactttc
    21421 ttagaaatgt aggcaatatc cccagagtca atccgcacac ccataaagtt aatctgatca
    21481 cccagctcac gcgccacctg aatggcagct ggtacaccga tgcgaagggt gtcataggta
    21541 tccacaagaa agacacaatt tttgtgggtc gcagcgtaag ccttgaaagc ttcatagtca
    21601 ttgccataaa cctgtaccaa ggcatgggca tgggttccca aaacaggaat gtcaaagagc
    21661 ttacccgcac gcacgttgct ggttccattg gcgccaccaa tcacagctgc gcgtgttccc
    21721 cagatggccg catccatttc ttgagcccga cgtgtcccaa actccatcaa gggttcatct
    21781 tcgataaccg aacgaatacg agctgccttc gtcgccacca aggtctggta gttgacgatg
    21841 ttcaaaagag ccgtttcgac caactgacat tgggctagag gtccttccac ctgcacaatc
    21901 ggttcattag caaaaaccaa atccccttct tgggcagaac gaacggtcaa ctccaacttg
    21961 aaattgcgaa ggtaatccaa gaacgcccca tgataaccaa gcgactccaa ataggctata
    22021 tcactatctg aaaaacgcaa gtcttcaaga tagttcacaa ttctttccaa acctgcaaaa
    22081 accgcatagc cgttcttaaa aggctgttgg cggaaataca cctcaaagac cgccttctta
    22141 ttgtgaatcc cttggtcaaa gtaaacctgc atcatgttga tctggtacaa gtccgtgtgc
    22201 aatgtcaaac tatcatctgg atacatactt ttcctacttc cttagctaga aacccatgaa
    22261 aattttcaag aactttcatg tattccaata aattagtact attatatcac attttagctg
    22321 gattgagaaa agagtaacaa gctattctcc actctccaat tcatccatat cttgttcaaa
    22381 ttttttctga gcccattcgc catagctctt aagaccaaga ttgccaataa agatccacgg
    22441 aaggtaaatg atataagtaa tgacccaagc agacaggtat ttaaaattca aaggattgtg
    22501 ctgataaatt tctatgttga attgataatt ctgcaacatc aaaagagccg taatagccaa
    22561 ggttaggaaa aaacaaccca aaatcgtaaa atgaaaacga ctatagtagg tcactcccag
    22621 ataacgggca cgattgaaaa agtaaaatgt ccctatgatg ataacgatta gcagcatatt
    22681 agaattaaaa aggcttggtg ctaatactga aatgatataa gataggagcg acaaagcaat
    22741 gcagatatag aaactttcag agcccgcttt attgaacagt tgttcttctc tttcgtctag
    22801 taattgataa taataaaatc tatttttcat cttcttcctc ccaaaatagt tggtctaggg
    22861 ttttccctaa acatctgcaa atagactggc agagcgagag actgggattg tattttcccg
    22921 cctctattaa accaatagtc tggcgtgtca ccccgacagc ctctgccagt tgaccttgtg
    22981 ttaaatcacg ctctacccga gctaatttta attttaaatt tttagccacc ttcgtcctcc
    23041 ttatagtttt aatactcatc tactcttaaa aaatccaaaa ccaacacaag ctatcagcta
    23101 tttattataa ccccattaat ttgcattcca gtattatctt cagccgaaaa tcagtatttt
    23161 aggttgtttg aaataaactt cctagtttac tcttttattt ttatttagta ttagctttag
    23221 taagatcttt taaacgaatt tttattgctt atatttcttg tttagtttag ttggtttcat
    23281 atcactatta tataatgctt ttggaaatga gcctagtata agtcaaaaac gtgttgaata
    23341 gtgaaagcag gagcatacca agatgactga ttttttactg tattttaggt atgcaaaata
    23401 atactaaatg aaactaaaat gaatacttct tgcttttctt gagagtgaaa aagtacaata
    23461 aaatgattgt agtgattacc acaagatact gactaataga catcgtattt gaagccacaa
    23521 atacaggtaa agaataaaaa ggaagaagtt caattgcttt gataaacaaa tcattactag
    23581 tattcatcat catcgtattt aatatattag ggataaagag tagtaaagct actaaaatac
    23641 caaataccaa gccacttttc aatttgtata aatagaaaat gtaagataat agaaaataaa
    23701 acaggactaa caaaattgta ttgactacaa tagctactat aaaatctaat cctaaatcac
    23761 ctggaatacc caatttactt actatgacta gtaacacaat gccattcaaa gcataaataa
    23821 tggaaactga gatggcatat agaaaattag acaagacgta aatcatccga ttcttctgtt
    23881 gattataaaa caaacttacc gtattgtggg aaaaatctct actaataact cgattagcat
    23941 gtataacagc cattaacata ccgagcatag cataaaagtt tgaaatatgc ttaataccaa
    24001 gcgatgtctc ttgagtcttt agaataaaga atgtaagcaa tatcggcggt ataaacgaga
    24061 taagcaaact gagatatatt acgcctgatg aatataaatt tcttatattt tccttaagaa
    24121 aattcaattt atttaatttc atgattataa ccttccttta ttttgaacga tttaagtaaa
    24181 tatctttaag cgtctctttt ttagtttcaa aatcaactac tttaatagag ttttcgttaa
    24241 aaaatttaaa aagctcacta ctttgaatat tcccagacat agtaattctc agtccctctt
    24301 cctgaacaat atccccaaat tcttgtttgg taatgaaaat gtctctatct gtagctgatg
    24361 aaaaagctat ctcaaacaag aaattatgac tatcttttcc tactttttga aatgtcaaaa
    24421 gcccgctctc caagaaaaga accctctcac aaatttcttc aatgtcttct aatttatgac
    24481 tcgatattaa aattcccacg ttttcattta aagctaattt ttttagaacc gctaaaacta
    24541 tttgtgatga ttcaatatct aaaccattag tcggttcatc taaaatcaat atatcaggtt
    24601 tcgtaacgag agttagaagc aaagctaatt tttgttttgt acccaaagaa taggtcttta
    24661 cttttttatt aatagactga gtcaaatcta actcttggat caaacttcta aatctttctt
    24721 gattgtagtc aacaccatat aaatttgaca aatattttaa attctctaaa cctgttttag
    24781 ataaaaataa ttttggttct tcgattaaat acccaatatt atcactgctt ataatattac
    24841 ctgaagtcgg ttgattattc tgaacaagaa ttttcatcaa cgtactctta ccaactccat
    24901 ttctccctac tagaccaaca atttcaccct tgttaagtgc aaaatttata tctttgagaa
    24961 tgattgaatg accataatgc ttacttacat ttataactta cattttttat tcctccatta
    25021 atattcatgg tttgctcttt gattcttatt gagtttaaaa agttgcgcct ctttttaaca
    25081 acattatatc atatatctaa cttaatgcaa tatataaatg tcattttgta aaattttatt
    25141 aacaaaaaac tctctacaac aaaataatag agagttttct gcttattaat ttttttcaaa
    25201 atatctaaac atcacttctt tgtttaattt gataggcttt gatacctaag ctccgacttt
    25261 atcacttaaa aaataaaaaa ggacagctaa tctcttgcgc atcaagggat ttcgccattc
    25321 tttaatctcg tttaagtgtt gtatatggag ctttgcataa ttttttaaaa ctaaacaact
    25381 acattaaac
//
LOCUS       DBEJAU010000031        24613 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC323 isolate 683620
            SAMN38261939-rid24807223.denovo.031, whole genome shotgun sequence.
ACCESSION   DBEJAU010000031 DBEJAU010000000
VERSION     DBEJAU010000031.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261939
            Sequence Read Archive: SRR26833919
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 24613)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 24613)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576303.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576303.1
            Genome Coverage       :: 154x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/19/2025 01:05:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,121
            CDSs (total)                      :: 2,078
            Genes (coding)                    :: 1,943
            CDSs (with protein)               :: 1,943
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 36
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 72 of 135
            Pseudo Genes (incomplete)         :: 63 of 135
            Pseudo Genes (internal stop)      :: 51 of 135
            Pseudo Genes (multiple problems)  :: 46 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..24613
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261939-rid24807223.denovo.031"
                     /strain="GPSC323"
                     /isolate="683620"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            complement(1..186)
                     /locus_tag="ACL29Z_001314"
                     /pseudo
     CDS             complement(1..186)
                     /locus_tag="ACL29Z_001314"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001810556.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
     gene            complement(199..972)
                     /locus_tag="ACL29Z_001315"
                     /pseudo
     CDS             complement(199..972)
                     /locus_tag="ACL29Z_001315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000566051.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0008168 - methyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
     gene            complement(1418..2173)
                     /locus_tag="ACL29Z_001316"
     CDS             complement(1418..2173)
                     /locus_tag="ACL29Z_001316"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000567550.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="epoxyqueuosine reductase QueH"
                     /protein_id="HGR0069621.1"
                     /translation="MIDVEEILCKMPPNQKINYDRVMQKMVQAWEKNEQRPTILVHVC
                     CAPCSTYTLEYLTKYADVTIYFANSNIHPKVEYHKRVYVIKKFVSDFNERTGNTVQYL
                     EAPYEPNEYRKLVRGLEEEPEGGDRCKVCFDYRLDKTAQVAMDLGFDYFGSALTISPH
                     KNSQTINSIGIDVQKIYTTHYLPNDFKKNQGYKRSVEMCEEYDIYRQCYCGCVYAAQA
                     QNIDLVQVKKDATAFLLDKDVEKDYSHIKFIVD"
     gene            complement(2311..3933)
                     /gene="groL"
                     /locus_tag="ACL29Z_001317"
     CDS             complement(2311..3933)
                     /gene="groL"
                     /locus_tag="ACL29Z_001317"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018166362.1"
                     /note="60 kDa chaperone family; promotes refolding of
                     misfolded polypeptides especially under stressful
                     conditions; forms two stacked rings of heptamers to form a
                     barrel-shaped 14mer; ends can be capped by GroES;
                     misfolded proteins enter the barrel where they are
                     refolded when GroES binds; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_function: GO:0140662 - ATP-dependent protein folding
                     chaperone [Evidence IEA];
                     GO_process: GO:0042026 - protein refolding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="chaperonin GroEL"
                     /protein_id="HGR0069622.1"
                     /translation="MSKEIKFSSDARSAMVRGVDILADTVKVTLGPKGRNVVLEKSFG
                     SPLITNDGVTIAKEIELEDHFENMGAKLVSEVASKTNDIAGDGTTTATVLTQAIVREG
                     IKNVTAGANPIGIRRGIETAVAAAVEALKNNAIPVANKEAIAQVAAVSSRSEKVGEYI
                     SEAMEKVGKDGVITIEESRGMETELEVVEGMQFDRGYLSQYMVTDSEKMVADLENPYI
                     LITDKKISNIQEILPLLESILQSNRPLLIIADDVDGEALPTLVLNKIRGTFNVVAVKA
                     PGFGDRRKAMLEDIAILTGGTVITEDLGLELKDATIEALGQAARVTVDKDSTVIVEGA
                     GNPEAISHRVAVIKSQIETTTSEFDREKLQERLAKLSGGVAVIKVGAATETELKEMKL
                     RIEDALNATRAAVEEGIVAGGGTALANVIPAVATLELTGDEATGRNIVLRALEEPVRQ
                     IAHNAGFEGSIVIDRLKNAELGIGFNAATGEWVNMIDQGIIDPVKVSRSALQNAASVA
                     SLILTTEAVVANKPEPVAPAPAMDPSMMGGMM"
     gene            complement(3949..4233)
                     /gene="groES"
                     /locus_tag="ACL29Z_001318"
     CDS             complement(3949..4233)
                     /gene="groES"
                     /locus_tag="ACL29Z_001318"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="co-chaperone GroES"
                     /protein_id="HGR0069623.1"
                     /translation="MLKPLGDRVVLKIEEKEQTVGGFVLAGSAQEKTKTAQVVATGQG
                     VRTLNGDLVAPSVKTGDRVLVEAHAGLDVKDGDEKYIIVGEANILAIIEE"
     gene            complement(4503..4898)
                     /locus_tag="ACL29Z_001319"
     CDS             complement(4503..4898)
                     /locus_tag="ACL29Z_001319"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000282444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HGR0069624.1"
                     /translation="MYNKVILIGRLTSTPELHKTNNDKSVARATIAVNRRYKDQNGER
                     EADFVNMVLWGRLAETLASYATKGSLISVDGELRTRRFEKNGQMNYVTEVLVTGFQLL
                     ESRAQRAMRENNAGQDLADLVLEEEELPF"
     gene            complement(4976..5737)
                     /locus_tag="ACL29Z_001320"
     CDS             complement(4976..5737)
                     /locus_tag="ACL29Z_001320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family NAD(P)-dependent oxidoreductase"
                     /protein_id="HGR0069625.1"
                     /translation="MAKNVVITGATSGIGEAIARAYLEQGEDVVLTGRRIDRLEILKS
                     EFAVSFPNQTVWTFPLDVTDMVMVKTVCSDILETIGRIDILVNNAGLALDLAPYQDYE
                     ELDMLTMLDTNVKGLMAVTRCFLPAMIKVNQGHVINMGSTAGIYAYAGAAVYSATKAA
                     VKTFSDGLRIDTIATDIKVTTIQPGIVETDFSTVRFHGDKERAASVYQGIEALQAQDI
                     ADTVVYVTSQPRRVQITDMTIMANQQATGFMIHKK"
     gene            complement(5770..6396)
                     /gene="ytpR"
                     /locus_tag="ACL29Z_001321"
     CDS             complement(5770..6396)
                     /gene="ytpR"
                     /locus_tag="ACL29Z_001321"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YtpR family tRNA-binding protein"
                     /protein_id="HGR0069626.1"
                     /translation="MIFTYNKEYVGDVLMVIVKNSGDAKLDVERKGKVARVFLKDNGE
                     TVAWNIFEVSSLFEIAERGQVFLTDEQVARLNQELQAEGFTEEIVNDKEPKFVVGEIV
                     EMVAHPDSDHLNICQVAVASDKTVQIVAGAPNARVGLKTIVALPGAMMPKGNLIFPGE
                     LRGEKSFGMMCSPRELHLPNAPQKRGVLELSEDPVVGTPFDPAKHWTA"
     gene            complement(6412..6729)
                     /locus_tag="ACL29Z_001322"
     CDS             complement(6412..6729)
                     /locus_tag="ACL29Z_001322"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000615765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin family protein"
                     /protein_id="HGR0069627.1"
                     /translation="MIQPASLEELASLVEKAGKKVFLFVADWCGDCRYIYPALPEIEE
                     TNPEFTFIRMDRDQYMDLAKLWDVYGIPSLVVLEKDKEIGRFVNRDRKSKQQINDFLA
                     GLK"
     gene            complement(6726..7025)
                     /locus_tag="ACL29Z_001323"
     CDS             complement(6726..7025)
                     /locus_tag="ACL29Z_001323"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001013970.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4651 domain-containing protein"
                     /protein_id="HGR0069628.1"
                     /translation="MNGMKAKKMWMAGLALLGIGSLALATKKVADDRKLMKTQEELTE
                     IVRDLFSDMGEIATLYVQVYESSLESLVGGVIFEDGRHYTFIYENEDLVYEEEVL"
     gene            complement(7223..7303)
                     /locus_tag="ACL29Z_001324"
     CDS             complement(7223..7303)
                     /locus_tag="ACL29Z_001324"
                     /inference="COORDINATES: protein motif:HMM:NF039231.3"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0069629.1"
                     /translation="MASSGKMLRNTYTPDSYYVGNLGAWQ"
     gene            complement(7310..7501)
                     /locus_tag="ACL29Z_001325"
     CDS             complement(7310..7501)
                     /locus_tag="ACL29Z_001325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000291825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding protein"
                     /protein_id="HGR0069630.1"
                     /translation="MYYSVDDVVSNAFKKRMILDSFFAFNCSGTMKVSTWVYDKGEWY
                     YVSSSGSMIANDWVKDNGK"
     gene            complement(7662..8336)
                     /locus_tag="ACL29Z_001326"
     CDS             complement(7662..8336)
                     /locus_tag="ACL29Z_001326"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000725744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0069631.1"
                     /translation="MKKKAFGIVLLVLAAWILLQGNFGIPSLDGKIWPLLGIVFFAYK
                     SIESILRRHLTSAVFTGLLALIIANYAYDLLPVTNHSLIWASILVVLGVGYLTHSSKF
                     WNEKKWWYNGKKTVVTDKEVAFGSGTFYKQDQDLVDDQVEVAFGDAKIYYDNAEMLGD
                     FATLNIEVAFGNATVYVPQHWRVDLKVETSFGAAKADAPVAPTSKTLTIRGDVAFGKL
                     EIVYVK"
     gene            complement(8342..8788)
                     /locus_tag="ACL29Z_001327"
     CDS             complement(8342..8788)
                     /locus_tag="ACL29Z_001327"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000776610.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LytTR family DNA-binding domain-containing
                     protein"
                     /protein_id="HGR0069632.1"
                     /translation="MKLRIEIDGNLEETEIVIKTPTLTDEIADLQRLLQESKAPRLTF
                     YKGTGEYYLDLSEILFFETEGSKIYAHNQKEAYEVRLKLYELESILPRYFNRVSKSTI
                     ANIRQIYSVDKSFSGTGTISFYQTHKEVHVSRHYQSLLKENLRNMR"
     gene            complement(8902..9405)
                     /locus_tag="ACL29Z_001328"
     CDS             complement(8902..9405)
                     /locus_tag="ACL29Z_001328"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000800945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatase PAP2 family protein"
                     /protein_id="HGR0069633.1"
                     /translation="MKNYQEWYRNISSRLTSRPILLFLLRSFNRLMTVAMPLVYLILL
                     VTTYLQLGLGQQVGVYVLIPASGFVALSLFRKKINHPRPYETWDICPLLDKDSSGRSM
                     PSRHVFSATIISMACLHASLPIGLVCLIFSALLGLVRVLGGVHYPKDVLVGYACGLVW
                     GFLFFLF"
     gene            complement(9402..9764)
                     /locus_tag="ACL29Z_001329"
     CDS             complement(9402..9764)
                     /locus_tag="ACL29Z_001329"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2200 family protein"
                     /protein_id="HGR0069634.1"
                     /translation="MSQKLYNMKFAAVYLALIAKVERKGGKAESVHQVTSWLTGYEVS
                     DVLACLDRDVTYGDFFRQAPYYVPERIAITGKICSVRIEEIDDPLMQEIRRLDKLVDW
                     LAKGKTSQQVLEKYEKHK"
     gene            complement(9830..10861)
                     /locus_tag="ACL29Z_001330"
     CDS             complement(9830..10861)
                     /locus_tag="ACL29Z_001330"
                     /EC_number="7.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000506433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGR0069635.1"
                     /translation="MGFLLMGALFIVLPRTMVSAKRINQVLDLHSSIQNPVQVQLTDE
                     NFKGQVEFKDVTFRYAANSEAVIEHVSFKAETGQTVAFIGSTGSGKSTLVNLIPRFYD
                     VSAGEILVDGVNVQDYDFSATAHAGQKVAIVGSTGTGKTTIVNLLMKFYEIDKGSIHI
                     DGVDTKAMTRSEVHDAFSMVLQDTWLFEGTIRDNLIYNQIGISDERMMEASKAVGIHH
                     FIMTLPDGYDTILDDTVTLSVGQKQLLTIARALLKDAPLLILDEATSSVDTRTEELIQ
                     KAMDRLMEGRTSFVIAHRLSTIRNADLILVMKDGNIIEQGNYEELMAQGGFYADLYNS
                     QFTEDEAEE"
     gene            complement(10868..11689)
                     /locus_tag="ACL29Z_001331"
                     /pseudo
     CDS             complement(10868..11689)
                     /locus_tag="ACL29Z_001331"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000601671.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
     gene            complement(11706..12177)
                     /locus_tag="ACL29Z_001332"
                     /pseudo
     CDS             complement(11706..12177)
                     /locus_tag="ACL29Z_001332"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000360543.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family winged helix-turn-helix
                     transcriptional regulator"
     gene            complement(12301..13017)
                     /locus_tag="ACL29Z_001333"
     CDS             complement(12301..13017)
                     /locus_tag="ACL29Z_001333"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015604432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YebC/PmpR family DNA-binding transcriptional
                     regulator"
                     /protein_id="HGR0069636.1"
                     /translation="MGRKWANIVAKKTAKDGANSKVYAKFGVEIYVAAKKGDPDPESN
                     SALKFVIDRAKQAQVPKHIIDKAIDKAKGNTDETFTEGRYEGFGPNGSMLIVDTLTSN
                     VNRTAANVRAAFGKNGGNMGASGSVSYLFDNKGVIVFGGEDADAVFEQLLEADVDVDD
                     VEAQEGTITVYTAPTDLHKAIVALRESGIEEFQVTELEMIPQSEVELSGEDLETFEKL
                     YSVLEDDEDVQKIYTNVDGF"
     gene            complement(13898..15313)
                     /gene="ply"
                     /locus_tag="ACL29Z_001334"
     CDS             complement(13898..15313)
                     /gene="ply"
                     /locus_tag="ACL29Z_001334"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001284359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cholesterol-dependent cytolysin pneumolysin"
                     /protein_id="HGR0069637.1"
                     /translation="MANKAVNDFILAMNYDKKKLLTHQGESIENRFIKEGNQLPDEFV
                     VIERKKRSLSTNTSDISVTATNDSRLYPGALLVVDETLLENNPTLLAVDRAPMTYSID
                     LPGLASSDSFLQVEDPSNSSVRGAVNDLLAKWHQDYGQVNNVPARMQYEKITAHSMEQ
                     LKVKFGSDFEKTGNSLDIDFNSVHSGEKQIQIVNFKQIYYTVSVDAVKNPGDVFQDTV
                     TVEDLKQRGISAERPLVYISSVAYGRQVYLKLETTSKSDEVEAAFEALIKGVKVAPQT
                     EWKQILDNTEVKAVILGGDPSSGARVVTGKVDMVEDLIQEGSRFTADHPGLPISYTTS
                     FLRDNVVATFQNSTDYVETKVTAYRNGDLLLDHSGAYVAQYYITWNELSYDHQGKEVL
                     TPKAWDRNGQDLTAHFTTSIPLKGNVRNLSVKIRECTGLAWEWWRTVYEKTDLPLVRK
                     RTISIWGTTLYPQVEDKVEND"
     gene            complement(15324..15734)
                     /locus_tag="ACL29Z_001335"
     CDS             complement(15324..15734)
                     /locus_tag="ACL29Z_001335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000595750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0069638.1"
                     /translation="MIKRGDVVVLYLPFPTISSDLAVKNHMYICIDNSMTKNKELVKN
                     QTFKPALLTRRLVKNFMIEEPDLARNPFTRPTLIDLDKVFMLDNTVIPTSYLARRRRN
                     VSEELYEEILDHLVQPRLISLNKSEFMQLNPGTY"
     gene            complement(15727..16335)
                     /locus_tag="ACL29Z_001336"
     CDS             complement(15727..16335)
                     /locus_tag="ACL29Z_001336"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000083609.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0069639.1"
                     /translation="MSQSSYLSPLLWLKKEADKEKMSATQCQIFFFYYQMFELLFARE
                     SDMKDLCLGTKGFYFSQLEKNLLSGVSRFLKNLEGKVTLKANQEVSARKALFLALTTS
                     QSDWQELAPVFDFYQTIGRLENPSLLSSQDRQHLMWIYQSALEKDYIVKVIGDKHFVL
                     KRQDATKLTARQTQTLEILSQSEDLVNPVYVTLGEKGVLLLD"
     gene            complement(16348..16806)
                     /locus_tag="ACL29Z_001337"
     CDS             complement(16348..16806)
                     /locus_tag="ACL29Z_001337"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000186958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4231 domain-containing protein"
                     /protein_id="HGR0069640.1"
                     /translation="MTPEEMYLTERLDVQIAHFLKKSVQHRRRYKVLKITEIVAGFLI
                     AVFCAIPMPGDRYRLISVALSSLGLLCEGIINLYNAKENWISYQKTAQLLEKEKFLYQ
                     CQTEKYAGKTKAFALFVKTCEGLISEEINQWESIQSKEVAASADAPVKKE"
     gene            16931..17327
                     /locus_tag="ACL29Z_001338"
                     /pseudo
     CDS             16931..17327
                     /locus_tag="ACL29Z_001338"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase family protein"
     gene            complement(18068..18325)
                     /locus_tag="ACL29Z_001339"
     CDS             complement(18068..18325)
                     /locus_tag="ACL29Z_001339"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0069641.1"
                     /translation="MRERSATGAQGLSKSIKKHLNDITRLTASLLGDEKLSAITSSSV
                     KADIHRFVIELEPVKSTILQNDDISLDQNEIFEILKNFLDG"
     gene            complement(18384..18935)
                     /locus_tag="ACL29Z_001340"
     CDS             complement(18384..18935)
                     /locus_tag="ACL29Z_001340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001111259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0069642.1"
                     /translation="MPVNTKVIFQEMFADFQNYYVLIGGTATSIVLDSQGFKSRTTKD
                     YDMVIIYEVKNKEFYTTLNHFLELGEYQGSQKDEKAQLFRFTTTNPEFPSMIELFSIL
                     PEYPLKKDGREIPLHFDQDASLSALLLDEDYYNILVHEKETIQGYSVLSNCGLYSSKI
                     SSNHVSFHLQPQNSVLSSLQLAS"
     gene            complement(18925..19710)
                     /locus_tag="ACL29Z_001341"
     CDS             complement(18925..19710)
                     /locus_tag="ACL29Z_001341"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001101214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0069643.1"
                     /translation="MNVKKIMSIFQSFYVDVSIEELTLTLPISFVKRFEYTQMTFHKE
                     SFLLIKEKRRGSLSSFVTQARTMGEKANMDVVLVFSKLSDSEKKQLLQARVPFVDFKG
                     NLFFPPLGLVLNANDTEIPKELTPSEQLTWIAFLLPDGDIKQIKSVSNLLYGGAYALS
                     YSTFLAETDENTSYVIWQRKFNQLSLPLSQHVLKGKMLEIWKYRPFVSEFWNDFKNNH
                     DKQFVDPISLYLTLKDDDDPRIEEESEALENMILQYLGEDDAS"
     gene            complement(20118..20543)
                     /locus_tag="ACL29Z_001342"
     CDS             complement(20118..20543)
                     /locus_tag="ACL29Z_001342"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000204059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0069644.1"
                     /translation="MTSRVFIDADCISAFLWVGTEHLLEKLYSGKIVIPQEVYDEINI
                     PTIPHLKSRIDQLVTKGSAEIVSIDIGTEEYALYRDLTRNYDSNKIIGKGEATSIFLA
                     KKHNGILGSNNLRDVKPYVEEFSLEHMTTGDILIEAFKA"
     gene            complement(20674..21063)
                     /locus_tag="ACL29Z_001343"
                     /pseudo
     CDS             complement(20674..21063)
                     /locus_tag="ACL29Z_001343"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000749821.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ImmA/IrrE family metallo-endopeptidase"
     gene            complement(21076..21282)
                     /locus_tag="ACL29Z_001344"
     CDS             complement(21076..21282)
                     /locus_tag="ACL29Z_001344"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000366086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0069645.1"
                     /translation="MDLSNKAPNLRKKLGADGESPIDIFKLVQKIENLTLVFYGLGKN
                     ISRVCYKGTQFSLIAVNSDMSLGR"
     gene            complement(21269..21430)
                     /locus_tag="ACL29Z_001345"
     CDS             complement(21269..21430)
                     /locus_tag="ACL29Z_001345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000289348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HGR0069646.1"
                     /translation="MNMINVCDVGKRIKELRISSNLTQDKIAEYLSLNQSMIAKMEKG
                     ERNITNGFK"
     gene            complement(21776..22732)
                     /gene="lytA"
                     /locus_tag="ACL29Z_001346"
     CDS             complement(21776..22732)
                     /gene="lytA"
                     /locus_tag="ACL29Z_001346"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000405235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase LytA"
                     /protein_id="HGR0069647.1"
                     /translation="MEINVSKLRTDLPQVGVQPYRQVHAHSTGNPHSTVQNEADYHWR
                     KDPELGFFSHIVGNGCIMQVGPVDNGAWDVGGGWNAETYAAVELIESHSTKEEFMTDY
                     RLYIELLRNLADEAGLPKTLDTGSLAGIKTHEYCTNNQPNNHSDHVDPYPYLAKWGIS
                     REQFKHDIENGLTIETGWQKNDTGYWYVHSDGSYPKDKFEKINGTWYYFDSSGYMLAD
                     RWRKHTDGNWYWFDNSGEMATGWKKIADKWYYFNEEGAMKTGWVKYKDTWYYLDAKEG
                     AMVSNAFIQSADGTGWYYLKPDGTLADKPEFTVEPDGLITVK"
     gene            complement(23108..24478)
                     /locus_tag="ACL29Z_001347"
     CDS             complement(23108..24478)
                     /locus_tag="ACL29Z_001347"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001036275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HGR0069648.1"
                     /translation="MNKKRTVDLIHGPILPSLLSFTFPILLSNIFQQLYNTADVLIVG
                     RFLGQESLAAVGATTAIFDLIVGFTLGVGNGMGIVIARYYGARNFTKIKEAVAATWIL
                     GALLSILVMLLGFLGLYPLLQYLDTPAEILPQSYQYISMIVTCVGVSFAYNLFAGLLR
                     SIGDSLAALGFLIFSALVNVVLDLYFITQLHLGVQSAGLATIISQGLSAVLCFYYIRK
                     SVPELLPRFKHFKWDKSLYADLLEQGLAMGLMSSIVSIGSVILQFSVNTFGAVIISAQ
                     TAARRIMTFALLPMTAISASMTTFASQNLGAKRPDRIVQGLRIGSRLSISWAVFVCIF
                     LFFASPALVSFLASSTDGYLIENGSFYLQISSAFYPILSLLLIYRNCLQGLGQKILPL
                     VSSFIELIGKIVFVVLIIPWAGYKGVILCEPLIWVAMTVQLYFSLFRHLLIKEGKAIL
                     ATKVQS"
BASE COUNT         7436 a         5411 c         4228 g         7538 t
ORIGIN      
        1 acaaaaattc tctatcgaaa cattgatatt tgataataat tcaaaaaatg ttgaaagaga
       61 aatttcattt tctccccttt caaatctaga aagttgagat tttgatatag aatcagctgc
      121 agcatactct aaagaatatc cgtttaattt tctaaaatat cgaaaagctt ctccgtaatt
      181 tttaacactt tcattccctt aactttcttt tcgagcgata aacataccat attctttagg
      241 aatgatcaac ataccattat taaactcact ttccaatctt ttacgtatta tttcctcttc
      301 tagtgaacct atttctgaaa ttcctttaaa cgattggatg tatttaacta ggtcatctat
      361 actagttacc tgtaactcat catcatagag taatgtatcg acagagttaa aacacctact
      421 caggtacctt ttaccatttt gtaaagtaaa cgttttattt tctaaatctt aattaacctc
      481 atctttaaat aaatttgcca aataatttac aactccattt tcaccaaatg tagcacagta
      541 aaaaatgcct tcggttttta agactctatt cacctcagag agagctttag gaatatcatt
      601 cacatgatgt agaagcatat tagcaataac aatatcaaaa gtttcattct caaaagaaat
      661 cttttgaata tccattatct catagttgac attgtctcta tttccaatca ctgacttcgt
      721 tgattttacc atatctttag aaaaatctgt aacaatcaac tgcttcattt tatctataga
      781 atcactatta cttttccaca gttctcctgt accacatccc aattctagaa cctttacttc
      841 atcagtgatt tggtagttag aaaatatcca attattaaat cccaatttat tttttgaata
      901 cttcttatgc aattctactc gaatatcaag attatcatga cttttatatt gttcaattac
      961 tttatcaatc attttaaatg acctccactc tataatttgg cattatatca caagaataaa
     1021 gatagtgtta aataagttgt ataaatgcaa aaaaggaata ttccgttata gcagagttgt
     1081 aacacatttc tataaagaaa tttattccta cgactcagtt tggcatgctt aacttcctaa
     1141 ctcaaaaaca aagcatcgat taatttatcc gttcttcttt tgaaacagat ttgaactgat
     1201 aattgctcgt tttaatttaa gaagctcttt tgagcaaaac ttcatttttt taagagtcca
     1261 acaatttctg tctatcgctt ttctactagc aaaaaaccta ccttgaggca agttttcatt
     1321 tatatatcta atttcgtaat agtatagtaa aatgaaataa ggacagtcaa atcgatttct
     1381 aacaatgttt tagaagtaaa ggtgtactat tctagtttca atctactata aatttgatat
     1441 gagaatagtc tttctcaaca tccttatcca acaagaatgc tgtggcgtcc ttcttaactt
     1501 gaaccaggtc aatattctgg gcttgggctg catagacgca gccacaataa cattgacgat
     1561 agatatcata ctcctcacac atctctactg aacgtttgta gccttgattt ttcttgaaat
     1621 cgttgggaag atagtgggtc gtgtaaattt tttgcacatc gattccgatg ctattgatgg
     1681 tttgagaatt cttatgagga ctgatggtca aggctgaacc aaagtagtca aagcccaagt
     1741 ccatagccac ttgcgctgtt ttatccagtc ggtagtcaaa acaaaccttg caacggtcgc
     1801 caccttcggg ctcctcctct agtcccctaa ctagttttcg gtattcattg ggttcgtagg
     1861 gagcttctag gtactgaacc gtatttcctg tccgctcatt aaaatcacta acaaatttct
     1921 tgatgacata cacccgctta tggtattcta ccttgggatg gatattagaa ttggcaaaat
     1981 agatggtcac atctgcatac ttggtcaaat attctagtgt ataggtacta caaggggcac
     2041 agcaaacatg cacgagaatg gttggccgct gctcattttt ctcccatgct tgtaccattt
     2101 tctgcatgac acgatcataa ttaatcttct gattgggggg catcttgcac agaatttctt
     2161 ctacatcgat catgttcttc tcctttttct agtcttattt tatcatataa gttaggagag
     2221 ctcaaatcaa tttagaagtg aatattataa aaagaagggt tagtcattcc ctccttttgt
     2281 gttttttata agttgttttc tatagaaagc ttacatcatc ccgcccatca tacttggatc
     2341 cattgctgga gctggggcta ctggttctgg tttattggct acgactgctt ctgttgtcaa
     2401 aatcaagctt gctacagatg ctgcattttg tagggctgaa cgactcactt taactggatc
     2461 aatgatacct tgatcaatca tgttaaccca ctcgccagtt gctgcgttga atcctatacc
     2521 aagctcagca tttttcaaac gatcgataac gatagatcct tcaaatcctg cattgtgagc
     2581 aatttgacga acgggttctt ccaaagcacg gagaacaata ttacgtcctg ttgcttcatc
     2641 tcctgtcaat tccaaggtag caacagctgg aatcacattg gcaagagctg ttccaccacc
     2701 tgcaacaata ccttcttcaa cagctgcacg agtagcgttg agggcatctt caatgcggag
     2761 tttcatttct ttcaactcag tttcagttgc ggctccgacc ttaataaccg ctacaccacc
     2821 tgacaatttg gccaagcgtt cttgcaattt ttcacggtca aattcagaag ttgtagtttc
     2881 gatttgagac ttgataaccg caacacggtg agaaatcgct tcaggatttc ctgcaccttc
     2941 tacaataacc gtgctatctt tgtccacggt cactctcgct gcttgaccaa gagcttcaat
     3001 tgtcgcatct ttcaactcaa gaccaaggtc ttctgtgata actgttccgc ctgttaagat
     3061 ggcgatatct tcaagcatgg ctttgcgacg gtcaccaaaa ccaggtgcct tgactgctac
     3121 tacgttgaag gttccacgaa tcttgttcaa aacaagagtt ggaagagcct cgccatccac
     3181 atcatccgca ataatcaaga gtggacgatt gctttggaga atgctttcca aaagtggcaa
     3241 gatttcttgg atattggaaa ttttcttgtc tgtaatcaaa atgtacggat tttcaaggtc
     3301 agccaccatt ttttcgctat cagtcaccat gtactgtgaa aggtaaccac ggtcaaactg
     3361 cattccttct acgacttcaa gctctgtttc cataccacgt gactcttcga tggtgatgac
     3421 accgtctttg ccaacttttt ccattgcttc agagatgtac tcaccaactt tttcagaacg
     3481 agaagatacg gctgcaactt gagcgatagc ttctttattg gcaacaggga tggcgttgtt
     3541 tttcaaagct tcaactgctg cggcaactgc cgtttcaatc ccacgacgaa taccgattgg
     3601 atttgcacct gctgtgacgt ttttgattcc ttcacggacg attgcttggg tcaaaacagt
     3661 tgcagttgta gttccatcac ctgcgatatc attggttttt gaagctactt ctgataccaa
     3721 tttggcaccc atattttcaa aatggtcttc caattcgatt tctttggcaa tggtcacacc
     3781 gtcattggta atcaaaggtg aaccgaatga cttttcaaga acgacattgc gaccttttgg
     3841 tcccaaggtt actttaacag tgtctgcaag gatatcgaca ccacgaacca tggctgaacg
     3901 ggcatctgat gaaaatttaa tttcttttga catacttact ttctccttct attcctcaat
     3961 gattgccaaa atgttagctt cgcctacgat gatgtacttt tcatcgccat ctttgacatc
     4021 aagacctgcg tgggcttcaa ctaagacacg atctccagtt ttaacacttg gagcaaccaa
     4081 gtcaccgttc aaggtacgaa caccttgtcc agtagccaca acttgagctg ttttggtttt
     4141 ttcttgggct gagcctgcaa ggacaaagcc cccaacggtt tgttcttttt cttctatttt
     4201 taagaccaca cggtccccta atggtttcaa catctgattt cctccataat gagatagata
     4261 ttattagcac tctttgaact tgagtgctaa ttcataattc tattgtatca cttggtcaga
     4321 aatagtcaag aaaaaagtct gactttctca agataaaaag cctgagacca actcagactt
     4381 tttaatgttt atactcaatg aaaatcaaag agcaaactag gaagctagcc gcaggctgct
     4441 caaagcattg ctttgatgtt gtggataaag ctaacgtggt ttgaagagat tttcgaagag
     4501 tattaaaatg gcaattcttc ctcttccaag accaaatctg ccaaatcttg gcctgcatta
     4561 ttttcacgca tggcacgttg agcacgactt tctaagagtt ggaatcctgt cacaaggact
     4621 tcggttacat agttcatctg accatttttc tcaaagcgac gggtacgcaa ttctccatca
     4681 acggaaatga gactaccttt ggttgcgtag cttgccaaag tttctgctag cctgccccat
     4741 aggaccatat tgacaaaatc agcttcacgt tcaccgtttt ggtctttgta acgacggttg
     4801 acagcgatag ttgctcgcgc taccgacttg tcattgttgg ttttgtgcaa ttctggtgta
     4861 gacgttaaac gcccaatcaa gataacttta ttatacatat tttcttcctc ctacttatct
     4921 attcgtagga aatcaaaaaa agttacagaa atttgtaact tttcgaggaa atttcttatt
     4981 ttttatgaat catgaaacct gtcgcctgtt gattggccat aatggtcata tctgtaatct
     5041 gaacacggcg aggctgactg gtcacataga ctactgtgtc tgcaatatcc tgagcttgca
     5101 aggcttctat tccttggtaa acggacgcag cccgctcttt atcaccatga aaacgaacag
     5161 ttgagaaatc tgtttcgaca atcccaggct gaatggttgt caccttgata tccgttgcga
     5221 tggtatcaat tcgcagtcca tccgaaaagg tcttaaccgc tgccttggta gctgagtaaa
     5281 cagcggcacc agcataggcg tagattcctg cggttgaccc catattgata acgtgacctt
     5341 gattgacttt tatcattgct ggcaagaaac agcgagtaac cgccatcaga cctttaacat
     5401 tggtatccaa catggtcaac atatccaact cctcatagtc ttgataggga gccaagtcaa
     5461 gagccagtcc ggcgttgttg accaagatat caatcctccc tatcgtttct agaatatcag
     5521 agcaaacagt cttcaccatg accatatccg tcacatctag tggaaaagtc cagacagttt
     5581 gatttggaaa gcttactgca aactccgact tgaggatttc taatctgtct atccgtcgtc
     5641 ctgttagaac gacatcctca ccctgctcca gataagcacg cgcaatcgct tcaccgattc
     5701 ctgaggttgc tcccgtaatc actacatttt ttgccatctt atttccttct atcagatgct
     5761 gacaagttcc taggcagtcc agtgtttcgc tgggtcgaac ggtgttccga caactgggtc
     5821 ttctgataat tcaagcaccc cacgtttttg cggagcattt ggcagatgca attcacgagg
     5881 actgcacatc ataccaaaac tcttttcacc acgaagttca cctgggaaaa tgagattccc
     5941 ttttggcatc atagctccag gaagcgcgac aatggttttc aaccccacac gcgcattggg
     6001 agctcctgca acgatttgta cagtcttatc acttgcgact gcaacttggc agatgttgag
     6061 gtggtcacta tctggatggg ctaccatctc aacaatttca ccgacaacaa acttaggttc
     6121 cttatcatta acaatttctt ctgtaaaacc ttccgcctgc aactcttggt tcaaacgagc
     6181 gacttgctca tctgtcaaaa agacttgacc gcgctctgca atttcaaata aacttgaaac
     6241 ttcgaaaata ttccaagcca ctgtttcccc attatctttg agaaaaacac gggctacctt
     6301 gcctttgcgc tccacatcca gtttggcatc tccgctattt ttcacgatga ccataaggac
     6361 atcaccgaca tattctttgt tatacgtaaa aatcattgtt tcctttttct cctatttcaa
     6421 tcctgctaaa aaatcattga tttgttgctt gcttttacgg tcgcgattga caaaacgacc
     6481 gatttccttg tccttttcta gaacaacaag gctaggaatt ccgtaaacat cccagagttt
     6541 ggccaaatcc atatactgat ctcggtccat tcgaataaag gtgaactctg gattggtctc
     6601 ctcaatctct ggtaaggcag gataaatata acgacaatcg ccacaccagt ctgccacaaa
     6661 aaggaagacc ttcttgcccg ctttttccac taaagatgct aattcttcta aacttgctgg
     6721 ctgtatcata agacttcctc ctcatagact aggtcttcat tttcatagat aaaggtataa
     6781 tgacggccat cctcaaaaat gacgccacca accaagctct ccagactgct ttcgtaaact
     6841 tgaacataga gggtcgcaat ttcccccatg tcggaaaaaa ggtctcgcac aatctctgtc
     6901 aactcttcct gagtcttcat gagcttacgg tcatctgcaa cttttttcgt agcaagagca
     6961 aggcttccga tacctagcag agccaagcct gccatccaca tttttttagc tttcatacca
     7021 ttcattttaa cacaaaaaag gcttcaggac aaatgaggaa gcagcagaaa agcaagtaaa
     7081 aagcctcttc ctttaaggaa aaagacttct tatactaaga gcaaactagg aagctagccg
     7141 caggctgctc aaaacacggt tttgaggttg tagataaggc gacgttgacg tggtttgaag
     7201 agattttcaa agagtattat tcttattgcc aggcacctaa gttgccaacg tagtaactat
     7261 caggtgtgta ggtattgcga agcatcttac ctgatgaagc cagataatac tacttgccat
     7321 tgtctttgac ccaatcattc gcaatcatgg aaccagaaga acttacataa taccattctc
     7381 ccttgtcata aacccaagta ctgactttca tggttcctga gcaattaaag gcaaaaaaac
     7441 tgtccaatat cattcgtttt ttaaaagcat ttgacactac atcatctacg ctgtagtaca
     7501 tagatacatc aaacgtaaaa gccaaaatat cgaaaaatat acaactttta aaggcagcat
     7561 ttcatttttt aaagtctaac aaccatagaa ctgaaatcag agcaaggcat caatttccta
     7621 ctcttagtac gtctattttg atggttgaag tgaagatttt tttatttaac gtagacaatt
     7681 tccaacttcc caaaagccac atctccacgg atagtcaagg ttttgctggt tggggctaca
     7741 ggagcgtcag ccttagctgc accaaaggag gtttctactt tcaaatctac acgccagtgt
     7801 tgtggaacat agacggttgc atttccgaag gccacttcaa tatttaaagt tgcaaaatca
     7861 cctagcatct ctgcattatc atagtagatt ttagcatccc caaaagcgac ttccacttgg
     7921 tcatctacga gatcttgatc ttgcttatag aaggtcccgc taccaaaagc gacttcctta
     7981 tccgtgacga ctgttttttt cccattgtac caccattttt tttcattcca gaacttactt
     8041 gaatgcgtca gataaccaac accaagtacc accaagatgc tagcccaaat aagagaatga
     8101 ttggtaactg gtaacaagtc ataagcgtaa tttgcaatga tgagcgccag taaacctgta
     8161 aaaactgccg aagtgagatg acgtctaagg atggactcaa tggacttata agcaaaaaaa
     8221 acaataccta gtaaaggcca tattttacca tccaaagaag gaattccaaa attcccttgc
     8281 agcaagatcc aagctgctaa aaccaacaaa acaataccaa atgctttctt tttcatgttt
     8341 tttacctcat gtttcttaga ttttctttta ggagggattg gtaatgccgt gagacatgaa
     8401 cctccttgtg cgtctgataa aaggaaatgg tgcccgttcc tgaaaaggac ttgtccactg
     8461 agtaaatctg acggatgttt gcgatcgttg acttggaaac tcgattaaaa tagcgaggca
     8521 agatagactc caactcatag agcttgaggc gaacctcata agcttccttc tggttatgag
     8581 cgtagatctt gctcccttct gtttcaaaga agagaatttc tgacaggtct agataatatt
     8641 cacctgtccc cttgtaaaaa gtcaacctcg gagcctttga ctcttgcaag agccgttgca
     8701 agtctgcaat ttcatctgtc aaagtggggg tcttgatgac aatttcagtc tcctctaaat
     8761 tgccgtcaat ctcaattcgt aacttcatca catctccttt ctgactctac tatatcaaag
     8821 ctaagttagg aatacaaggg caaaaaagca agtggtcaat ttgaagcagt aagtggttgt
     8881 aggactagct taacttacat gtcagaatag gaagaaaagg aatccccaca ccaaaccaca
     8941 agcatagcca accaagacat ccttgggata atgaacaccc cctaaaaccc tcaccaaccc
     9001 cagcaaagct gaaaagatca agcatactaa gccaataggt agactagcat gcagacaggc
     9061 catggagatg atagttgccg aaaagacatg gcgactgggc atcgaccgtc ccgaactatc
     9121 cttatcaaga aggggacaga tatcccaagt ttcataaggt ctcgggtgat tgattttctt
     9181 acgaaacagg gacaaggcca caaaacctga tgcaggaata agcacataaa ccccaacttg
     9241 ctgaccaagt cctagttgca ggtaagtggt gactagcaag atcagataga ccaggggcat
     9301 ggcgactgtc atcaaacgat tgaaactgcg taataggaat aaaagaattg gacgactagt
     9361 tagtctggag ctgatatttc gataccattc ttgataattt ttcatttatg cttctcatac
     9421 ttttctagaa cttgttgaga tgttttcccc ttggcaagcc aatccactag cttgtccaag
     9481 cgacgtattt cctgcatcag aggatcatca atttcctcaa tacggacact gcaaatcttc
     9541 cctgtaattg caattcgttc agggacataa tatggtgctt gtctaaaaaa atctccgtaa
     9601 gtaacatccc tatccagaca agcaagaaca tcactcactt cataccctgt caaccaactg
     9661 gtcacttggt gaactgactc tgcctttcca ccctttcgct caacttttgc aatcaaggct
     9721 aagtagacag cagcaaattt catattgtat aatttctgac tcatacttct ctctttctat
     9781 gtgtactagt ataaataaga aaaagaaggc cgtcaagcct tcttttgatt tattcttctg
     9841 cttcatcttc tgtaaattga ctattgtaca agtcagcgta gaagccacct tgcgccatca
     9901 gttcctcata gttgccttgc tcgatgatat ttccatcttt catgaccaag atcaagtctg
     9961 catttcggat ggttgacaag cggtgggcaa tgacaaagga tgtgcgtcct tccatcaaac
    10021 ggtccatggc tttttggatc aattcctctg tccgtgtgtc aacagaagaa gtcgcctcat
    10081 ccaaaatcaa aagcggtgca tccttaagaa gggcacgagc aatagtcaat agttgttttt
    10141 gtcctacaga caaggtcacg gtgtcatcca agatggtatc atagccatct ggcaaggtca
    10201 taataaagtg gtgaattccc acagccttac tagcttccat cattcgttca tcactaatcc
    10261 ctatttgatt atagatgaga ttgtctcgaa tagttccttc aaagagccag gtatcctgca
    10321 agaccattga aaaggcatcg tgcacttctg aacgcgtcat agccttggta tccacaccat
    10381 caatgtgaat acttccctta tcaatctcat agaatttcat caaaagattg acaatggttg
    10441 tcttaccagt cccagtcgac ccaacaatgg caaccttttg accagcatga gctgtcgcag
    10501 agaagtcata gtcttgaaca ttgacaccgt ccaccagaat ttctcctgct gacacgtcgt
    10561 agaaacgtgg aatcagattg accagagttg atttaccaga acctgttgac ccaataaagg
    10621 ccactgtttg accagtttct gctttaaagc taacatgttc aataactgcc tccgaatttg
    10681 ccgcatagcg gaaggtcaca tccttaaact cgacctgacc tttgaagttt tcatcagtca
    10741 gctgtacttg aacagggttt tggatagaag aatgcaaatc taaaacttga ttaatccgct
    10801 tagcagagac catagttcgg ggaagaacga tgaagagtgc tcccatgaga aggaagccca
    10861 tgacaaccta catagcataa gacatgaaaa caatcatgtc actaaagaga ggcagacgcg
    10921 ctatcggagc agcgtcgtta atcacatagg ccccaatcca gtaaatcgcc acactcaaac
    10981 cacttgaaat ccccatcatg ataggattca aaatagccat aagacggttg acaaacaaat
    11041 tttaacgggt caattcatca tttactgctg caaatttttc attttgataa tcctctgcat
    11101 tgtaggcacg aacgacacga atacctgtta aactctcacg agtgatactg ttcagtttat
    11161 ctgtcagccc ctgaatcaag gactgttttg gaaaggctaa cgtcatcaaa acggtcgtca
    11221 tcaggacgtt gataatcact gccacaagta cggcccagag ccagtattct gaatgaccta
    11281 aaatcttccc aatagcccag atagccataa ttggaccaca cgttaccact tgcaagccca
    11341 tagtaatcaa catttgaact tgagtaatgt cattggtagt acgcgtcaag aggctaggaa
    11401 ttgaaaattt cttaatctct gtctgcgagt aatccaaaac tcggttaaaa atatcacttc
    11461 tcagcctact agtataagaa gccgccactc gggatgcaaa aaatccaact gcaactacgg
    11521 acaagaaggc aagaaaggac attcccatca tcatgcttgc cggctgccac aactcatcta
    11581 aattagtttc ttgactacct agcaaatccg taattttcga gatataggtc ggcactttca
    11641 actctagata gaccaaaaag caagtaaaga gaatggctag taaaatcatc ccccattctt
    11701 ttctactaat tcttttggct aatttcttta ttctctcctc ctattccctt gatattttgc
    11761 ctgtagttga ccgataacct tctcaaaaat cagtaattca tcttcatcaa tgtcttccat
    11821 caactgcttg tctatgcgtt caaaaaaagc cttaacctgt tgcatctgag aacgtgcttt
    11881 gtccgtcaga cgaacaaact tagcccgctt atcaacagga ctcgcctcca attccaccaa
    11941 accattttgc actatacgct taaccagatt actagcaaca gacttggtaa tattgagttc
    12001 ctgctcgata tctttaatca agaccaagtc ttggtttttc tcgcgattat ccaaaaaatg
    12061 cacaacctga ccttgcggcc cacccataaa ttcaatgccg caacgtttgg cttccttttg
    12121 caccatcagg tgaatttgat gaccaaaacg cttaaagact aacatcggtt tatccataat
    12181 ctcccccttc taaataaaaa tagttctctg gagaataatt aaatttctat gagaactatt
    12241 ttcttgatta aaaaaatccc aagtgatttt ctcacttagg atcatgttct ataggttaaa
    12301 ttaaaaccca tctacgttcg tataaatctt ttggacgtct tcgtcgtctt caagaacgct
    12361 gtaaagtttt tcaaaggttt caaggtcttc gcctgacaat tccacttctg actgaggaat
    12421 catttccaat tcagtcactt ggaattcttc aataccagac tcacggaggg caacgatagc
    12481 cttgtgaagg tcagttggcg ctgtgtaaac tgtgattgta ccttcttgtg cttctacgtc
    12541 atccacatcc acatccgctt cgagcaattg ctcaaagact gcgtccgcat cttcacctcc
    12601 aaatacaata acacctttgt tgtcaaagag gtaagaaaca gaacctgaag cgcccatgtt
    12661 tccgccgttt ttaccaaagg ctgcacggac attggctgct gtacggttga cgttagaagt
    12721 caaagtatcc acaattagca tagagccatt tggcccaaaa ccttcgtaac gtccttctgt
    12781 aaaggtttcg tctgtgtttc ctttggcttt atcaatcgct ttatcgataa tgtgttttgg
    12841 cacttgggct tgtttagcac ggtcgataac gaatttcaaa gctgagtttg attctggatc
    12901 tggatcacct tttttagctg ctacatagat ttctacacca aattttgcat ataccttaga
    12961 gttagctcca tctttagccg ttttcttggc tacgatattg gcccatttac gtcccattag
    13021 gaatctcctt ttttcacatt ttaatcttta ttattataac acaagttttt ttgattttca
    13081 ctagaggaaa tggattttat tagcaaatca agctaggata gcactttacc tgctaagatg
    13141 gtcttacctt tctatcttta tcaacagaca ctcatccaca ttcaaaaaac aaactagacc
    13201 attatctgca aatagaaagt ttcagccaag tttgacaaag tcagctcaaa ttactgtttg
    13261 aagtttgtag atataagcga caaaaacaat catactgcac cttttgttga cagtctactc
    13321 cagacatatc atagttcaag taaatacttt gaaattcaac agttcttata ggcgctattg
    13381 tattctaaga aatcaataga agagtttcta agcaaacctc taatactcaa taaaaatcaa
    13441 agagcaaacc agaaagctag ccgcaggttg ctcaaaacac tgttttgagg ttgcggatgg
    13501 ggctgacatg gtttgaagag attttcgaag agtataattt acgtgttccc aagatggaga
    13561 agttagacta gtacactggc acttctaaac cattgctagc aattgatttg ttcatattta
    13621 atttcatttt ttccataaat gggtattaga tataaacagc aaaatatttc cgatacgtgt
    13681 cgttcttgaa tttccaatca tctaaaacaa gtaaaggata atcaatcccc tgtatatcaa
    13741 ggaattggct acccttttta cttttttaca cattctgttt gatagattca ttttaacatc
    13801 acgagcatac tccaatggaa atcgctaggc aagagataaa ctttcagata tccgcagaga
    13861 gatcatcgcc tctttttgtc gcaagcattc tcctctccta gtcattttct accttatctt
    13921 ctacctgagg atagagagtt gttccccaaa tagaaatcgt ccgcttacgc actagtggca
    13981 aatcggtttt ttcataaacc gtacgccacc attcccaggc aagcccggta cactctctaa
    14041 ttttgacaga gagattacga acattccctt ttaaaggaat actagtggta aagtgagccg
    14101 ttaaatcctg cccatttctg tcccaagcct taggagtcaa gacttcctta ccttgatgat
    14161 cataggataa ttcattccaa gtaatataat attgggcaac ataggcacca ctatgatcca
    14221 gcagtaaatc tccgtttctg taagctgtaa ccttagtctc aacatagtct gtactatttt
    14281 gaaaggtcgc aactacattg tcacgtaaaa aagaagttgt ataggaaatc ggcaagcctg
    14341 gatgatctgc tgtaaagcga ctgccttctt gaatcaagtc ctctaccata tccaccttgc
    14401 ctgttacaac tcgggcaccc gaacttgggt cgccccctaa aataaccgcc ttcacttctg
    14461 tattgtccaa aatctgcttc cactctgtct gaggagctac cttgactcct tttatcaaag
    14521 cttcaaaagc agcctctact tcatcactct tactcgtggt ttccaacttg agatagactt
    14581 ggcgcccata agcaacactc gaaatataga ccaaaggacg ctctgcagaa attcctctct
    14641 gttttaaatc ctctaccgtt acagtatctt gaaacacatc tcctggattt ttaacagcgt
    14701 ctacgctgac tgtataataa atctgcttaa aattaacaat ctgaatctgc ttttcgcctg
    14761 aatggacaga gttaaaatca atatcaagag aattccctgt cttttcaaag tcagaaccaa
    14821 acttgacctt gagttgttcc atgctgtgag ccgtgatttt ttcatactgc attctagctg
    14881 ggacattatt gacctgacca taatcttgat gccacttagc caacaaatcg tttaccgctc
    14941 cgcgaacact tgaattgctg gggtcttcca cttggagaaa gctatcgcta cttgccaaac
    15001 caggcaaatc aatactataa gtcatcggag cacgatcgac cgcaagaaga gtgggattat
    15061 tctctaacaa ggtctcatcc actacgagaa gtgctccagg atagaggcga ctgtcgttgg
    15121 tagctgttac agaaatatca cttgtatttg tcgacaagct ccgcttcttt ctttcgataa
    15181 caacaaactc atcgggtagc tgattaccct ctttgatgaa acgattttca atactttctc
    15241 cctgatgggt caagagtttc tttttatcgt aattcatagc tagtataaag tcatttactg
    15301 ctttatttgc catcttctac ctcctaataa gttcctggat tgagttgcat aaactcagac
    15361 ttgttcagcg aaatcagccg tggttggact aagtgatcca aaatttcctc gtacaattct
    15421 tctgagacat tgcgtcgccg tctggctaga taagaagtcg gaataaccgt attatccaac
    15481 ataaatacct tatctaagtc aatcaaggtt ggtcttgtaa aaggattacg agctagatcc
    15541 ggctcttcta tcataaagtt cttgaccaaa cgtctggtca agagagctgg tttgaaggtc
    15601 tgatttttaa ccaactcttt gtttttagtc atgctgttgt caatacagat atacatatga
    15661 ttcttcacag ccaaatcgct actaatagtc ggaaaaggca aataaagaac tacaacatct
    15721 cctctcttaa tcaagcaaga gcaccccctt ttctcctaat gtaacataga caggattgac
    15781 caagtcttct gattgactca gaatttccaa agtttgagtt tggcgcgctg tcaatttagt
    15841 agcatcttgt ctcttcaata caaaatgctt gtcgccaata accttgacaa tataatcctt
    15901 ctccaaagct gactggtaaa tccacatcag atgttgtctg tcctgagaac tcaagagaga
    15961 aggattttca agcctcccga tagtctgata aaaatcaaaa acaggagcta actcctgcca
    16021 atctgattgg ctagttgtca aggctagaaa aagggctttg cgagctgata cttcttggtt
    16081 agccttgaga gttactttcc cctccaagtt ttttagaaat cgggaaactc cagaaagcaa
    16141 atttttctct aactgcgaga aataaaaacc tttcgttccc agacataagt ctttcatgtc
    16201 gctttctcta gcaaataaga gctcaaacat ttgatagtaa aagaaaaata tctggcactg
    16261 ggtcgcgctc atcttttcct tatcggcttc tttttttaac cagagcaagg gcgacaggta
    16321 gctggattga gacatttcct ctacctccta ctctttttta actggagcat ctgcactagc
    16381 tgccacttct tttgactgga tactttccca ctggttaatc tcctctgaga taagaccttc
    16441 gcatgtcttg acaaataggg caaaagcctt ggtctttcct gcatatttct ccgtttggca
    16501 ttgatagagg aatttttctt tctccaggag ttgcgcagtt ttttggtaag aaatccaatt
    16561 ttcctttgca ttatacaaat tgataatccc ctcacacagc aagccgagac tggataaggc
    16621 aaccgaaatc aaacggtagc gatcacctgg cataggaata gcacaaaaga cagctatgag
    16681 gaaacctgcc acgatttctg ttatttttaa taccttatag cgtctacgat gttgaacgct
    16741 tttctttaaa aaatgagcta tctgtacgtc taatcgctct gtcaggtaca tttcttctgg
    16801 cgtcatattc gtaactcctt tcatttactt tgataaccat agtataacat atttgaatat
    16861 caaagtatag taaaaactgg actataactt attagacttc ctgcgaaaca aaatatggta
    16921 tagtagttct atgaattatg aagcaagtaa acaactaact gatgcacgat ttaagcgtct
    16981 tgttagtgtt cagcgtacca cttttgaaga gatgttagct gtattaaaaa cagcttatca
    17041 aaaaagtcgg acaagctggt aaaatcttgg ctgacagtgg ttatcaaggg ctcatgaaga
    17101 tatatcctca agcacaaact ccacgtaaat ccagcaaact caagccgcta acagttgaag
    17161 ataaagccta taaccatgcg ctatctaagg agagaagcaa ggttgagaac atctttgcca
    17221 aagtagaaat gtttaaaatg ttttcaacaa cctatcgaaa tcatcgtaaa cgcttcggat
    17281 tacgaatgaa tttgattgct ggtattatca atcatgaact aggattttgg tttcgcagga
    17341 agtctattat atatgcacag acatatgaaa tctttttgag acagcagtta tgatatattt
    17401 atccattcac aacatcttct gtactaatac tacaatattg gtacattttg attacacaat
    17461 cgtttcaaaa aatatgatgg aagcctgagt attttatagt aattcccttc ctatcaacta
    17521 gatcaaccag ttgagtgttg aatgttgaaa caccctagcc tcagcaaagg actatgatca
    17581 gcatttccta gccaatagga cgctccaaat cacctattct aagtccatca ctagcttggt
    17641 cagtaagata cagactgcaa ggcgagactg acgtggttga tgagattttg gaagagtatt
    17701 acaatcatag attcaccagt agacttgacc gcagatttaa ctatagtaga ttgaaactag
    17761 aatagtacat ctctgcttct aaaacattgt tagaaatcga tttgactgtc ctgatcaatt
    17821 tgtcctgttc tcgtttcatt tcactatact aaaaaaccac ctgaaacaaa tcaagtgact
    17881 agaggataaa aacaaagact aggcaaaaag ttttgaaaag caaaaaacgc ataatatcag
    17941 gtcttgaaaa accttgatac tatacgtttg attgtgggaa gattgacttc attttctcct
    18001 gaaattgaag ttttttctag tttccagata tagacgaatt caatatagcc atctcgctac
    18061 aattatttta accatcgaga aaatttttca gaatttcaaa aatttcattt tgatccaatg
    18121 aaatgtcatc attttgaaga atagttgact tcacaggctc taattctatc acaaagcggt
    18181 gtatgtctgc ttttacacta cttgatgtta tagccgataa cttttcatct cctagcaagg
    18241 aagctgtcaa acgggtaatg tcattcaaat gctttttaat ggacttactt aaaccttgag
    18301 cacctgtagc agagcgttcc ctcatatcca gccaagcttt agccttaaaa ataattaata
    18361 ctcaatgaaa atcaaagagc aaactaggaa gctagctgca ggctgctcaa aacactgttt
    18421 tgaggttgta gatggaagct gacgtggttt gaagagattt tcgaagagta taaaccacaa
    18481 ttactcaata ccgaataccc ctgaatggtt tctttttcat gcaccaatat attataataa
    18541 tcttcatcca ataataaggc tgataaacta gcatcttggt caaaatgtaa gggaatttct
    18601 cgaccgtcct tctttaatgg atattctggt aagatactaa atagttcaat catagaagga
    18661 aactcaggat tagttgttgt aaatcgaaaa agctgcgctt tctcatcttt ctgacttcct
    18721 tgatactctc ccaattctaa aaaatgattc aaggtagtat aaaattcctt attttttact
    18781 tcataaatga tgaccatatc ataatctttt gttgtgcgac ttttaaatcc ttgcgaatcc
    18841 aatacgatag aggtagcagt tcccccaatc agaacataat agttctgaaa atccgcaaac
    18901 atttcttgaa aaataacttt cgtattaact ggcatcatct tctcccagat actgtaatat
    18961 catattttct agtgcttcac tctcttcctc tatacgtggg tcatcatcat cttttaaggt
    19021 caaataaaga gaaatcggat ctacaaattg tttatcatga ttatttttaa aatcattcca
    19081 aaactcagat acaaaaggac gatatttcca tatctctagc atctttcctt ttaaaacatg
    19141 ctgagaaagt ggcaaggata actgattgaa ttttctctgc catatgacat agctagtatt
    19201 ttcatccgtt tcagctaaaa aagttgaata cgacaaagca taagcaccac catatagaag
    19261 gttagaaaca gattttatct gctttatatc gccatctggc aataaaaagg caatccacgt
    19321 taattgttcg ctaggtgtta attccttagg gatttcagta tcattcgcat tgagtactag
    19381 tcccaatgga gggaagaaga ggtttccctt aaagtctaca aacggaactc tagcttgaag
    19441 taattgcttt ttttcactgt ctgataactt cgaaaacacc aaaacaacat ccatattggc
    19501 tttttcaccc atagtgcgag cctgagtaac aaatgaactc aaactccccc ttctcttttc
    19561 tttaatcaat aaaaatgatt ccttatgaaa agtcatttga gtatactcaa acctttttac
    19621 aaaactgatt ggtaaagtca aagtcagttc ctcaatactg acatcaacat aaaaggattg
    19681 aaaaattgac attatctttt tgacattcat gttttttcct tattctatca tttttattat
    19741 attttatcat tcggtataat aaaatataag ttttttgata aaataaccaa aaactactcg
    19801 ctatcccctc tcacattacc ctacatatcg tttgacatgc gactgatagt tcaggaaaac
    19861 ttcaaggaga acttttctct catccactat gcaggactta ctatttcact tctactccta
    19921 taggctcaat ttgacacttt tctttttcga attgctcata tgcctcctga atagtgagtt
    19981 cgatttatcc aaatttattt ttgtctattt tgatgaatac ttccacgaag atagtctgaa
    20041 aatgaatttg caccaatttt ccttctcttt ttaagcatat tattccagat atgattgccc
    20101 tcttgttcag taataaatta cgctttaaac gcttcaatca gtatatctcc tgttgtcata
    20161 tgttctaaag aaaattcttc tacatatggt ttaacatctc ttaggttatt acttcctaat
    20221 atcccattat gctttttcgc taagaaaata gaagtcgctt ctcccttacc aataatcttg
    20281 ttactatcat aatttcttgt taaatctcta tataatgcgt attcttcagt tccaatgtct
    20341 atgctcacaa tctcagctga acccttagtt accaactggt ctatcctaga ttttaaatgg
    20401 ggaattgtag gtatattgat ttcatcatac acctcttgtg gaataacaat tttacccgaa
    20461 tagagctttt ctaaaagatg ttcagtgcca acccataaaa atgctgaaat acaatctgca
    20521 tcaataaata cacgactagt caaacgacaa ctccccctct tcatctagcc catatacaat
    20581 atcatatctg aaagcatcta gtaacagttc ctcatacttc ccttgcgaaa ttctgttatt
    20641 ttctaaaagt tgttcagtcg atttaatata gtgtcctaat accatttcct ttttactttc
    20701 tgacaaagga cgatataaac ttgtatcata gcctaatctt gaagctgtct ctataacact
    20761 aatatccata tttttaattt cttctgcatc aaggtatcca tcatttctca atctatataa
    20821 catagcttta tgactgatac cataaaactg acccaatttt ataatatctt ctacttcaag
    20881 atgagttcta ttggcatttt ctctgatttc ctcaaccatc ctatacagtg aagatgggaa
    20941 aattaaaaaa taagaagcaa actgatccgc ttttctttca gtttcatctc cttcaccaat
    21001 caagataaga ctgactgaac tcttcttcac ctcatcataa taaagatgat acagttcatg
    21061 tgctaaagaa aatctttacc ttcctaatga catgtctgaa ttgactgcaa tgagactgaa
    21121 ctgagttcct ttataacaga ctctgctaat attctttccg agtccataaa ataccagcgt
    21181 caaattttct atcttttgta ccaatttaaa aatatctatc ggcgattcac catcagctcc
    21241 caactttttt ctaagatttg gagctttatt acttaaatcc attcgtgata ttcctttcac
    21301 ctttttccat tttggcaatc atgctttgat tcaaagacaa atactcagca atcttatctt
    21361 gagtaagatt tgaagatatt ctaagttctt ttattctttt tccaacatca catacattta
    21421 tcatattcat acacctctca taaaaagaat agcacactct tgtcataatt ttttaaataa
    21481 aaaaattatg acaaaacaag gaagcaattt attgatgctg cttaaaaatc taaaattgat
    21541 gagttcctat caaaaatcgt atcttcaacc tcaaaacagt acttaaagct atccgactcg
    21601 gtttacattg tcaaatttag attttatttg agcataactt tctagtttgc tttctgattt
    21661 ttgtttaata tagtagcaaa cattgaagga aatatctcca caaaaaaacg catactatta
    21721 agctttttca agacctaata atatgcgctg ttctgatttg aaagacattc cattattatt
    21781 ttactgtaat caagccatct ggctctactg tgaattctgg cttgtctgcc agtgttccgt
    21841 ctggtttgag gtagtaccag cctgttccgt ccgctgactg gataaaggca tttgatacca
    21901 tggcgccttc tttagcgtct aagtagtacc aagtgtcctt gtacttgacc cagcctgtct
    21961 tcatggcacc ttcttcgttg aaatagtacc acttatcagc gattttcttc cagcctgtag
    22021 ccatttcgcc tgagttgtcg aaccagtacc agttgccgtc tgtgtgcttc ctccagcggt
    22081 ctgcaagcat atagcctgaa ctgtcaaagt agtaccaagt gccattgatt ttctcaaact
    22141 tgtcttttgg ataagagccg tctgagtgta cgtaccagta gccagtgtca ttcttctgcc
    22201 agcctgtttc aatcgtcaag ccgttctcaa tatcatgctt aaactgctca cggctaatgc
    22261 cccatttagc aagatatgga taagggtcaa cgtggtctga gtggttgttt ggttggttat
    22321 tcgtgcaata ctcgtgcgtt ttaattccag ctaaactccc tgtatcaagc gttttcggca
    22381 aacctgcttc atctgctaga ttgcgtaaga gttcgatata aaggcggtag tccgtcatga
    22441 actcttcttt ggttgaatgg ctttcaatca gttcaaccgc tgcataggtc tcagcattcc
    22501 aaccgccccc aacgtcccag gcaccattat caacaggtcc tacctgcatg atgcaaccgt
    22561 tcccaacaat gtgcgagaaa aaacctaatt ctgggtcttt ccgccagtga taatccgctt
    22621 cattctgtac ggttgaatgc ggattcccag ttgagtgtgc gtgtacttgc ctatatggtt
    22681 gcacgccgac ttgaggcaaa tctgttctta atttactcac attaatttcc atattctact
    22741 ccttatcaat taaaacaact cattttttac aatccagaac cagaaactcc tttatttcta
    22801 ccttacaaag aagacaatct tagtcacgat taggcttgta gatagaactt caaaacgcac
    22861 tattttgaca ctgtaaatag gactgacaag gtctgcattc tatctacaat aacaccccag
    22921 actaaaaagc ttttcaaaag tatattttta cagtctctat atgtcctttt cataaatact
    22981 atactttatt atatcatata aaagaagtca aaagtctgtt aaactatttt caacaccaaa
    23041 ctaaagaaga gaacacaagt tttttcgatt ttcactagag gaaatggatt ttattcagta
    23101 aatccaacta ggattgcact ttggttgcca aaattgcctt tccttctttt atcaagagat
    23161 gacggaatag tgagaagtac agttgaactg tcatggcaac ccagataaga ggttcacaaa
    23221 ggataacacc cttatatcct gcccaaggaa taatcaaaac cacaaaaacg atttttccga
    23281 ttagttcaat aaagctagaa actagaggaa ggatcttctg ccccaagccc tgcaagcaat
    23341 tgcgataaat caacaagagg ctcaaaatgg gataaaaggc tgaactgatt tgcagataga
    23401 aacttccatt ttctatcaag taaccatctg tcgaactagc caagaaggaa accaaggctg
    23461 gactggcaaa aaagaggaaa atacaaacaa aaactgccca ggatatactt aaacgactgc
    23521 cgattcgaag accttgaaca atgcggtcag gtcgcttagc tcctagattc tgagaagcaa
    23581 aggtcgtcat tgatgcagaa atagcggtca taggaagaag ggcaaaggtc ataatgcgtc
    23641 gagctgccgt ctgggcacta ataatcactg caccaaatgt attaacagaa aactgtaaaa
    23701 tcacactgcc gatagataca attgaactca tcaagcccat agccaaacct tgctccaaga
    23761 gatccgcgta caagcttttg tcccatttga aatgtttaaa ccgtggcaag agttctggca
    23821 cacttttacg aatataataa aagcagagaa ccgctgataa accttgcgaa ataatggtag
    23881 caagtcctgc ggattgaact cccagatgca attgcgtaat aaaatagaga tccagaacca
    23941 cattaaccaa ggcagagaaa atcagaaatc ccagggctgc tagactgtca ccaatagacc
    24001 gcaacaagcc tgcaaaaaga ttataagcaa agctgacacc tacacaggtc acaatcatag
    24061 aaatatattg ataagattga ggaagaattt ctgcaggagt atctaagtat tgcaagagag
    24121 gatacaagcc aagaaagccc agcaacataa ctagaatgct caaaagagca cctaaaatcc
    24181 aggtggctgc tactgcttcc ttgattttag tgaaattccg agccccataa taacgagcaa
    24241 tgacaatccc catgccattg ccaacaccaa gtgtaaaacc tacaatcagg tcaaaaatcg
    24301 ctgtcgtcgc tcctactgca gccaaggatt cttgaccaag aaatcgtcca acaatcaaga
    24361 catcagcagt gttatagagc tgttgaaaaa tatttgatag caagattgga aaggtgaagc
    24421 ttaagagcga gggaagaatc ggaccatgta tcaggtccac tgttcgtttt ttattcataa
    24481 agctattata tcagctttcc agaggagcga caagaaacag caaacttata tatagcggaa
    24541 tgaaataagg acagtcaaat cgatttttaa caatgtttta gaagtagatg tgtactattc
    24601 tagtttcgat cta
//
LOCUS       DBEJAU010000032        22816 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC323 isolate 683620
            SAMN38261939-rid24807223.denovo.032, whole genome shotgun sequence.
ACCESSION   DBEJAU010000032 DBEJAU010000000
VERSION     DBEJAU010000032.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261939
            Sequence Read Archive: SRR26833919
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 22816)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 22816)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576303.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576303.1
            Genome Coverage       :: 154x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/19/2025 01:05:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,121
            CDSs (total)                      :: 2,078
            Genes (coding)                    :: 1,943
            CDSs (with protein)               :: 1,943
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 36
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 72 of 135
            Pseudo Genes (incomplete)         :: 63 of 135
            Pseudo Genes (internal stop)      :: 51 of 135
            Pseudo Genes (multiple problems)  :: 46 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..22816
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261939-rid24807223.denovo.032"
                     /strain="GPSC323"
                     /isolate="683620"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            175..1656
                     /gene="mgaSpn"
                     /locus_tag="ACL29Z_001348"
                     /gene_synonym="mgrA"
     CDS             175..1656
                     /gene="mgaSpn"
                     /locus_tag="ACL29Z_001348"
                     /gene_synonym="mgrA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001205275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="virulence factor transcriptional regulator
                     MgaSpn"
                     /protein_id="HGR0069649.1"
                     /translation="MRDLLSKKSHRQLELLELLFEHKRWFHRSELAELLNCTERAVKD
                     DLSHVKSAFPDLIFHSSTNGIRIINTDDSDIEMVYHHFFKHSTHFSILEFIFFNEGCQ
                     AESICKEFYISSSSLYRIISQINKVIKRQFQFEVSLTPVQIIGNERDIRYFFAQYFSE
                     KYYFLEWPFENFSSEPLSQLLELVYKETSFPMNLSTHRMLKLLLVTNLYRIKFGHFME
                     VDKDSFNDQSLDFLMQAEGIEGVAQSFESEYNISLDEEVVCQLFVSYFQKMFFIDESL
                     FMKCVKKDSYVEKSYHLLSDFIDQISVKYQIEMENKDNLIWHLHNTAHLYRQELFTEF
                     ILFDQKGNTIRNFQNIFPKFVSDIKKELSHYLETLEVCSSSMMVNHLSYTFITHTKHL
                     VINLLQNQPKLKVLVMSNFDQYHAKFVAETLSYYCSNNFELEVWTELELSKESLEDSP
                     YDIIISNFIIPPIENKRLIYSNNINTVSLIYLLNAMMFIRLDE"
     gene            2018..3013
                     /locus_tag="ACL29Z_001349"
     CDS             2018..3013
                     /locus_tag="ACL29Z_001349"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000230211.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HGR0069650.1"
                     /translation="MVEQRKSITMKDVALEAGVSVGTVSRVINKEKGIKEVTLRKVQR
                     AIKTLDYIPDNYARGMKKNRTETIALIIPSIWHPFFSEFAYHVEKELLKYNYKLFICN
                     ADSDSQNEIEYIEMLKQNKVDGIIGITYSDIDKYILSDLPFVSIDRHFSENVCYVTSA
                     NYKGGQTAAEELVRRDNKHLAFIGSINMYENETILRSKGFREKAKELGVDVYNFEMKE
                     PLINPEDQIRIFLQSHKEIDGIFTINDMMALRVISVMKELGKIAPDDYQIIGFDGLKT
                     SVDQSYLVSTIVQDIGMMAKESVAMILKMIKREEILEKRIVIPTYFWGDKTTKKI"
     gene            3140..4450
                     /locus_tag="ACL29Z_001350"
     CDS             3140..4450
                     /locus_tag="ACL29Z_001350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter substrate-binding protein"
                     /protein_id="HGR0069651.1"
                     /translation="MRKGTMLSVVAGLSLAILAGCSGGTNSKQASSSNDIKVWVQFSD
                     ETNEGKAWQKVVDNFNQSGKSKYKVVTEYIPRSGSGGGYEDKVNAAITTNSLPDVITL
                     DGPNTAAYAKSKVITPLDDYLKDNNMDDVLDSIKQQGTYNGKFYAFGFSESNVGVYYN
                     KKMFKEAGIAESELPTLEKPWTWDEFNTIAKKLKDHYNKPAIDFRINSNDEMLPYAYM
                     PLIWSNNGSVVNEDGTKAEGYFNSKESVEAVQFIQNLVKEGYTTVSPVEKGFETGEYP
                     MLLSGSWTIADMNTNYKDIDFGILPYPVSSKTKKLVSPSGSWQLAVTTKSDKKEAASE
                     FVKFATNTESSEIISLGNSVLPIRKSTIENIKDKVSEPMRFLMEQNSKTAHARPVVVA
                     YPQVSRAFQQAMQDISYYEENPNVQKVLDTRTKEMQTAIDQSLK"
     gene            4546..5448
                     /locus_tag="ACL29Z_001351"
     CDS             4546..5448
                     /locus_tag="ACL29Z_001351"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000032537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HGR0069652.1"
                     /translation="MSKETVVDTKRREKIKDNILGYSFLAPALILLGIFLVIPVGMVI
                     YYAFTDYYLLTPDERKFVGLENFIRLTKDPIFLKSFLNTLKFVVWIIPVQLGAALGMA
                     LIVNKKRKGNMFFKVAFFAPVVMSLVVISILWLYLLNPNSGLLNAILNKVGIASQPFL
                     TSPKQAMYAIVFVSAWQGAGYQMLLFLGGMQNIPQDVYEAAELDGFSKWAQFRYITMP
                     LLKPTALFVLLTTLISAFKLIVQPMVMTQGGPLNSTITMVYYIYQQGFTDRLVGYSSS
                     IALVFTTLIGMISLVQRRVLKEDD"
     gene            5450..6295
                     /locus_tag="ACL29Z_001352"
     CDS             5450..6295
                     /locus_tag="ACL29Z_001352"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000819520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HGR0069653.1"
                     /translation="MKRFKPTTILEYILLTLLAGLFLFPMVWMVVSAMKPEADVYKNL
                     TSWQAFLPSLNPADWFKPYQEVFERFSIFTYLGNSIFYAGTFAIGSIIVNALAGFAFA
                     KVNFSGKKILFGFLLALLIIPVETVLIPQFTIINSLGLVNNRLAVIIPGLASVFNIYL
                     FRNFFIAIPEEILESAKMDGASIVRIFFRIMLPMSKPAVATVGVLSFISSWNDYIWPL
                     MVLTDSSKFSMQVAITTINTTQPVYINQVMAVLTISTIPLILVYVVAQKYIVQGLGGS
                     GTGIK"
     gene            6305..7624
                     /locus_tag="ACL29Z_001353"
     CDS             6305..7624
                     /locus_tag="ACL29Z_001353"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 32 protein"
                     /protein_id="HGR0069654.1"
                     /translation="MINKTFTVEKANRFIAENKHLVNTQYKPEEHFSAEIGWINDPNG
                     FVYFRGEYHLFYQFYPYDSVWGPMHWGHAKSKDLVTWEHLPVALAPDQDYDRNGCFSG
                     SAIVKDDRLWLMYTGHIEEETGVRQVQNMAFSDDGIHFEKISQNPVATGSDLPDELIA
                     ADFRDPKLFEKDGRYYSVVAAKHKDNVGCIVLLGSDNLVEWQFESIFLKGVEHQGFMW
                     ECPDYFELDGKDCLIMSPMRYQREGDSYHNINSSLLFTGKVDWGEKCFIPESVQEIDH
                     GQDFYAPQTLLDDQNRRILIAWMQTWGRTLPTHDQEHKWACAMTLPRILRLEDGKLRQ
                     FPVKKGQYQIQIDKDCHYHLGNDIDYLEFGYDSNAQQVYIDRSHLIQKILGEEEQDTS
                     RRYVDIEAKELEVVLDKNSIEIFVNQGEASLTATYYLTVPAELSRID"
     gene            complement(7834..7906)
                     /locus_tag="ACL29Z_001354"
     tRNA            complement(7834..7906)
                     /locus_tag="ACL29Z_001354"
                     /product="tRNA-Lys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(7871..7873),aa:Lys,seq:ctt)
     gene            complement(8171..9442)
                     /locus_tag="ACL29Z_001355"
     CDS             complement(8171..9442)
                     /locus_tag="ACL29Z_001355"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001113185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="replication-associated recombination protein A"
                     /protein_id="HGR0069655.1"
                     /translation="MPDNLALRMRPKTIDQVIGQEHLVGPGKIIRRMVEANRLSSMIL
                     YGPPGIGKTSIASAIAGTTKYAFRTFNATVDSKKRLQEISEEAKFSGGLVLLLDEIHR
                     LDKTKQDFLLPLLESGLVIMIGATTENPFFSVTPAIRSRVQIFELEPLSNQDVKEALQ
                     IALSNPERGFDFPIELDEDALDFIATSTNGDLRSAFNSLDLAVLSTPENDEGIRHITL
                     DIMENSLQRSYITMDKDGDGHYDVLSALQKSIRGSDVDASLHYTARLIEAGDLPSLAR
                     RLTVIAYEDIGLANPEAQIHTVTALDAAQKIGFPEARILIANVVIDLALSPKSNSAYV
                     AMDKALADLKTSGHLPIPRHLRDGHYSGSKELGNAQDYLYPHNYPGNWVKQDYLPEKI
                     RNHHYFQAEDTGKYERALAQRKEAIDRLRKI"
     gene            9712..9912
                     /locus_tag="ACL29Z_001356"
     CDS             9712..9912
                     /locus_tag="ACL29Z_001356"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000818079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0069656.1"
                     /translation="MKREVISNGNDGPSQEILIFTKQIRHWILSDQVISGKRKLFFRE
                     DTPKEILDLYENIKSKLDFAYQ"
     gene            10116..10295
                     /locus_tag="ACL29Z_001357"
     CDS             10116..10295
                     /locus_tag="ACL29Z_001357"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0069657.1"
                     /translation="MNLIFEEYQFVKIGDKKYRVRSVPMIHSTPPQSVLDRDTFTIDY
                     TDDELLDKEAVFTTH"
     gene            10432..10611
                     /locus_tag="ACL29Z_001358"
     CDS             10432..10611
                     /locus_tag="ACL29Z_001358"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397531.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system HicA family
                     toxin"
                     /protein_id="HGR0069658.1"
                     /translation="MPMTQKEMVKLLTAHGWIKTRGGKGSHIKMEKQGERLITIPHGE
                     LNKYTERGIRKQAGL"
     gene            10648..11100
                     /locus_tag="ACL29Z_001359"
     CDS             10648..11100
                     /locus_tag="ACL29Z_001359"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000961815.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0110001 - toxin-antitoxin complex
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system HicB family
                     antitoxin"
                     /protein_id="HGR0069659.1"
                     /translation="MLVTYPALFYYDDTDGTEATYFVHFPDFEYSATQGEGISEALAM
                     GSEWLGITVADLIESDGELPQPSDINSLSLIDNDPFKDDEDFVSTYDLDKSFISMVSV
                     DVSEYLGSQEPIKKTLTIPKWADKLGREMGLNFSQTLTDAIADKKVQA"
     gene            11391..11861
                     /locus_tag="ACL29Z_001360"
     CDS             11391..11861
                     /locus_tag="ACL29Z_001360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000257105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3013 family protein"
                     /protein_id="HGR0069660.1"
                     /translation="MATYGFLDVLEEELDKNFPFDFEISWDKRNHAVEVSFLLEAQNA
                     AGVEMVDEDGEVLSDDILFEEAVLFYNPAKSTVNEEDYLTVIPYLPKKGFSREFLAYF
                     ALFLKDTAEVGLDVLMDFLEDPEAEEFVMEWNQEVFEEGKVGLEEGEFYPYPRY"
     gene            11880..12968
                     /locus_tag="ACL29Z_001361"
     CDS             11880..12968
                     /locus_tag="ACL29Z_001361"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000719715.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004222 - metalloendopeptidase activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="site-2 protease family protein"
                     /protein_id="HGR0069661.1"
                     /translation="MKKIGTYLVYVLAFVFIMLAFACGTIAFAELGYSAVLAFTFGYA
                     FALLSMYLIFILHELGHAFCGYLTGYRLVAFGLGHFILTKKSGRFHLSRTAILKNVGA
                     QYIGLKEDESDQRIILMLSGGLMVHLGLILLAIVFGFLTRSWYFAGTWIFLNLSFFLN
                     NILPVDITDGAKIWELLQHPENTKYAYLVLRHSAQTLLAPQEYDLKDFVQAVPEDARG
                     SFADGVLGMQGEVSILEGKEEVAKQQFQALLERTTTPMMQTVAQLSLLHIALLEGDFE
                     QAEQYASIRQVKSFLSLKLSNLQVIQAWYQFKVKKDVDRTRKALKIARQKMDSSRMLR
                     DEKRYYENLLAELEKEMLEGTEDGTRNF"
     gene            12949..13083
                     /locus_tag="ACL29Z_001362"
                     /pseudo
     CDS             12949..13083
                     /locus_tag="ACL29Z_001362"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000418166.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="7,8-dihydro-8-oxoguanine-triphosphatase"
     gene            13217..14251
                     /locus_tag="ACL29Z_001363"
     CDS             13217..14251
                     /locus_tag="ACL29Z_001363"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HGR0069662.1"
                     /translation="MKKSDVLDLIKYHYEGRETEFRNQSIAIARNFNKHGDTQIAQYI
                     MGLMSQSDRFMPQIENPSEYLTPAKLDIGPLPLPLSIMNDLKGIINAVNHHIGINKFL
                     FVGSPGTGKTESVKQVARLIGKELLVVDFSHLVDSKLGQTVKNLATLFNEINNLPFKQ
                     NYIILFDEIDSIVLDRVNQNDLREMGRVTSAFLKELDRLSPEIVLIATTNLFENLDKA
                     VTRRFDAIIDFDRYTDEDKVEVATIILNELLKQFKNVARDLKLFKKIINSANVIPNPG
                     DLRNSIRTSLAFSDPSDPHDYQKRLLRSLHNGRNLSISKLSKLGFTVREIEILTGISK
                     SSVSRELSED"
     gene            14253..16496
                     /locus_tag="ACL29Z_001364"
     CDS             14253..16496
                     /locus_tag="ACL29Z_001364"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008288790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S8 family peptidase"
                     /protein_id="HGR0069663.1"
                     /translation="MNTLLTLRGKSFTQKSAKGRGPITIPADSIVTLNHLNELYTSLE
                     RVKEYWSNNTIIDGVLISVYYNRVLAKSNRIDGFFNVGGGNAIPNETIVGAKFSNDKS
                     RHIITHYISKEVLDKTIEHTKKVITIFKDYFASAPMTSMVFSDSSKFNQIDYSKYGLS
                     KSKFKQYLRDACFVKGFGIEQADMSTIRNSIVTIYDVKTNLLTLLKQLDIDVSEANIM
                     DQTTVLLDEKNIELLLLKAPYLVSMIVEDFSSLSPENFYNDGNTFYNNLPFPTNEPII
                     GVIDTLFDDRVYFNEWVEYHDLISPDISKGSQDYKHGTAVSSVIVDGASLNPKLDDGC
                     GRFRVRHFGISLQSGFNSFTIIKQIREIVSQNPDIKVWNLSLGSNDEIRENFISVEGS
                     LLDEIQFDNDVIFIIAGTNGIAPDGQRKKIGAPADSLNSIIVNSVDFSNQVVSYSREG
                     VVLSFFIKPDVSYYGGGNGDFINVCEPLGLARVAGTSFAAPFIARKMAYLIHIMGLSR
                     EEAKALLIDSAIPWNDKKTFADISLLGYGVVPIKIEDILSTPDDEIKFIVSDVSRAYE
                     TYNYDFPVPISKEHYPYVAKATMCYFPKCSRNQGVDYTNTEMQLSLGVLDKKGIKTIN
                     NDNQYSENAPGYVREKSARNIFRKWDNVKHLGEKFSSRKKAKPILNPSNPQWGMSVKT
                     IERLRNDDGYGIRFGVVVTLKELNGVNRIEDFIQQAELRGWLVNRLQVEAQVDLFNSL
                     NEEIEFE"
     gene            16547..17566
                     /locus_tag="ACL29Z_001365"
     CDS             16547..17566
                     /locus_tag="ACL29Z_001365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001028052.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AbiH family protein"
                     /protein_id="HGR0069664.1"
                     /translation="MNITYIVGNGLDLQYGLKTRYKDFYEFQNRTYISRKENEEEYSN
                     LIYESLFSDTVNDYENWSDFELSIGKLTKDNDLISSSIEIKEKFIDDFSEVVDDLREY
                     LRIQQEKNLEKGNAIDFISTLDNMRTSLPVINQPAIDKKYNENLYQHDIVNILTLNYT
                     NVIDKLYNESAKSFSNQLRTNNYKFHIAPPIHAHGTVDICTVLGVSDETQISNSFDEE
                     QKESLIKNLVLKNYRENMDVKNSDIIKNSDIIILYGVSLGETDGYIWNQIAEQSIRSS
                     VPVIIYHYVPHFDAGNPTRVKRLYRNVEDKFIQNSGIDLELEKKLRDNLIVVIGKTIF
                     NLMER"
     gene            17579..18529
                     /gene="prmA"
                     /locus_tag="ACL29Z_001366"
     CDS             17579..18529
                     /gene="prmA"
                     /locus_tag="ACL29Z_001366"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000451122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008757 - S-adenosylmethionine-dependent
                     methyltransferase activity [Evidence IEA];
                     GO_process: GO:0036211 - protein modification process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L11 methyltransferase"
                     /protein_id="HGR0069665.1"
                     /translation="METWQELKVTVKREGEELVSNLLIELGAQGVAIEDSMDYVGNVD
                     RFGEIFPEVEQQEEIVVTAYYPDTVDVATVESDLQARLAELTDFMDLGEVKMGTTALA
                     EEDWADNWKKYYEPARITHDLTIVPSWTDYEATAGEKIIKLDPGMAFGTGTHPTTKMS
                     LFALEQVLRGGETVLDVGTGSGVLSIASSLLGAKEIFAYDLDDVAVRVAQENIELNPC
                     MENIHVAAGDLLKGVEIEADVIVANILADILVHLTDDAYRLVKDEGYLIMSGIIKDKW
                     DMVRESAELSGFFLETHMIQGEWNACVFKKTKDISGVIGG"
     gene            18531..19274
                     /locus_tag="ACL29Z_001367"
     CDS             18531..19274
                     /locus_tag="ACL29Z_001367"
                     /EC_number="2.1.1.193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001188214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008168 - methyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0006364 - rRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (uracil(1498)-N(3))-methyltransferase"
                     /protein_id="HGR0069666.1"
                     /translation="MQQYFVKGSAISPVTIEDKETSKHMFQVMRLKEEDEVTLVFDDG
                     IKRLARVLDMENRQFELIQELNDNVELPVQVTIASGFPKGDKLEFIAQKVTELGASQI
                     WAFPADWSVAKWDGKKLDKKVEKLEKIALGAAEQSKRNIVPSIKLFEKKADFLAQLDQ
                     FDSIIVAYEESAKEGEAAALLQAVTGLETGAKLLFIFGPEGGLSPVEIESFEAKGAAL
                     VGLGPRILRAETAPLYALSALSVLVELEK"
     gene            19285..21081
                     /gene="pepF"
                     /locus_tag="ACL29Z_001368"
     CDS             19285..21081
                     /gene="pepF"
                     /locus_tag="ACL29Z_001368"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000435555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004222 - metalloendopeptidase activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="oligoendopeptidase F"
                     /protein_id="HGR0069667.1"
                     /translation="MEQKHRSEFPEKELWDLTALYQDCEDFLRAIEKAREDINQFSRD
                     YKGNLHTFEDFEKAFAELEQIYIQMSHIGNYGFMPQTTDYSNDEFANIAQAGMEFETD
                     ASVALTFFDDALVAADEEVLDRLGELPHLTAAIRQAKIKKAHYLGADVEKALTNLGEV
                     FYSPQDIYTKMRAGDFEMADFEAHGKTYKNSFVTYENFYQNHEDAEVREKSFRSFSEG
                     LRKHQNTAAAAYLAQIKSEKLLADMKGYDSVFDYLLAEQEVDRVMFDRQIDLIMKDFA
                     PVAQRYLKHVAKVNGLEKMTFADWKLDLDSALNPEVTIDDAYDLVMKSVEPLGQEYCQ
                     EVARYQEERWVDFAANSGKDSGGYAADPYRVHPYVLMSWTGRLSDVYTLIHEIGHSGQ
                     FIFSDNHQSYFNAHMSTYYVEAPSTFNELLLSDYLENQSNDPRQKRFALAHRLTDTYF
                     HNFITHLLEAAFQRKVYTLIEEGETFGASKLNSIMKEVLTDFWGDAIEIDDDATLTWM
                     RQAHYYMGLYSYTYSAGLVISTAGYLHLKHSETGAEDWLNLLKSGGSKTPLESAMIIG
                     ADISTDKPLRDTIQFLSDTVDQIISYSAELGE"
     gene            21327..21881
                     /locus_tag="ACL29Z_001369"
     CDS             21327..21881
                     /locus_tag="ACL29Z_001369"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2785 domain-containing protein"
                     /protein_id="HGR0069668.1"
                     /translation="MYQDLLRKIAEEKPNYNQEEIQWLFDHLGNPSPEIRNVLLNQGL
                     HYLSKEKDTRGFSSQYGWVHAFAHGADLLTEVVCHPDFPKNRVHEVFDILGQLFKRMS
                     IRFTDDEDWRLARVIYEPILQGKLEQEQVASWIKTVDFPIEEREDFYKFSNFRSCLVE
                     VYVQLDQRNSLQDDLKEAIQSFQY"
     gene            21992..22660
                     /locus_tag="ACL29Z_001370"
     CDS             21992..22660
                     /locus_tag="ACL29Z_001370"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000714831.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015267 - channel activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MIP/aquaporin family protein"
                     /protein_id="HGR0069669.1"
                     /translation="MKKFVAELIGTFMLVFVGTGAVVFGNGLDGLGHLGIAFAFGLAI
                     VVAAYSIGTVSGAHLNPAVSIAMFVNKRLSSSELVNYILGQVVGAFIASGAVFFLLAN
                     SGMSTASLGENALANGVTVFGGFLFEVIATFLFVLVIMTVTSESKGNGAIAGLVIGLS
                     LMAMILVGLKITGLSVNPARSLAPAVLVGGAALQQVWIFILAPIAGGVLAALVAKNFL
                     GTEE"
BASE COUNT         7245 a         3683 c         4811 g         7077 t
ORIGIN      
        1 attcacgccc tcaatagacg gtaaaataag aaaattgttt atatattgtc tccgtagtgt
       61 tattatacga aataaaagat tttaggaaaa gtcgttatat catgctatac ctattctttg
      121 tggtataatt gcaagaggtt taatccgata atttataaag agagaaagat attcatgaga
      181 gatttattat ctaaaaaaag tcataggcaa ttagaattat tagaattatt atttgaacat
      241 aaacgttggt ttcatcgttc tgaactagca gagttattaa attgtacaga acgtgcagtc
      301 aaagatgatc tatcccatgt taaatctgct tttcctgact tgatttttca ttcttctact
      361 aatggtatac gcattattaa taccgatgat agtgatattg aaatggttta ccatcatttc
      421 tttaaacatt caactcattt ttcgatttta gaattcatct tctttaatga aggttgtcaa
      481 gctgagagta tttgtaaaga attttatatc agttcatctt cgctctatcg tattattagc
      541 caaatcaata aagtgattaa aaggcaattt caatttgaag tcagtctgac ccctgttcaa
      601 atcattggaa atgagagaga cattcgttac ttttttgcac aatatttttc agaaaaatat
      661 tatttcctag aatggccatt tgaaaatttt tcatcagagc cactatctca attgttagaa
      721 ttggtttata aggaaacaag ctttccaatg aatttgtcaa cgcatagaat gctaaagttg
      781 ctcctagtta cgaacctata tagaataaag tttggtcatt ttatggaagt agataaagat
      841 tcttttaacg accaaagttt ggatttttta atgcaggcag aaggaataga aggtgttgct
      901 cagagttttg aatcagaata caatatctct ttagatgaag aagttgtttg ccaattattt
      961 gtgtcttact ttcaaaaaat gtttttcata gatgaaagtc tctttatgaa atgcgtaaaa
     1021 aaggatagtt atgttgaaaa atcttaccat ctattgagtg attttattga tcagatttca
     1081 gtcaagtatc agattgaaat ggagaataag gataatctga tttggcatct gcataatacc
     1141 gcacatctgt atcgtcaaga gttgtttact gagtttattt tatttgatca aaaagggaat
     1201 acaatcagga actttcaaaa tatttttcca aaatttgttt cagatataaa aaaagagctt
     1261 tctcactatt tagagactct tgaggtttgt tctagttcaa tgatggtaaa tcatctatct
     1321 tataccttca tcactcatac caaacatttg gtgattaatt tgctacaaaa tcagcctaaa
     1381 ctaaaggttt tagttatgag taattttgat cagtatcatg caaaattcgt tgcagagaca
     1441 ctttcttatt actgtagcaa taattttgaa ctggaagttt ggactgaatt agaattatca
     1501 aaggaatctt tagaagattc accttatgat atcattattt ctaattttat tattcctcct
     1561 attgaaaata agagactcat ctattcaaat aatataaaca cggtctcact catatacttg
     1621 ttaaatgcca tgatgtttat tcgattagat gagtaaccaa aaataacaaa aaaacgctat
     1681 ttcgcgtttg aactgtacct caaaagttag acagaaaaaa tctaattttt ggggtgtttt
     1741 tgttaagaaa agaccttcaa tcatttaagc aaaatgtaca tctagattta tagccctcta
     1801 aaactcttgc tttttttgta gaagatacga aaaaagccat aaaaccaagg cttttcctgt
     1861 tttatgtaga tgtttacaca tgaaaattga agtattttca aaagctaatt ggagtgattt
     1921 tattcatgat gggataaatg atctggccaa aaatgattga gaaatagttg cttaaaaagc
     1981 atttgcatga tactatatat tgaaaggagg tgataatatg gtagaacaaa gaaaatcaat
     2041 taccatgaaa gatgttgctt tagaagcagg agttagtgtt ggaactgttt cacgtgtaat
     2101 taataaagaa aaaggcatta aagaagtaac tttaaggaaa gttcaaaggg ctataaaaac
     2161 attggactat atccctgata attatgctcg aggtatgaaa aagaatagaa cagaaactat
     2221 cgctttgatt attccgagca tatggcatcc atttttttcg gagtttgcct atcatgttga
     2281 gaaagagtta ttaaaatata attataaatt atttatttgt aacgctgata gcgattcaca
     2341 aaatgaaatc gaatatatcg aaatgttgaa acaaaataaa gtggatggaa ttattggtat
     2401 tacatattct gatattgaca aatatatttt atctgattta ccgtttgtaa gtatagatag
     2461 acatttttcg gaaaatgtat gctatgttac ttcagcaaat tacaaaggag gacaaactgc
     2521 agcagaggaa ctggttagaa gggataataa gcaccttgct tttattggtt caattaatat
     2581 gtatgagaat gagactatac tcagaagtaa aggattcaga gaaaaagcta aggaattagg
     2641 agtagatgtc tataattttg aaatgaaaga acctttaata aatcctgaag atcagataag
     2701 aatttttttg caatctcata aagaaattga tggtatattt acaataaatg atatgatggc
     2761 tctgagagtt attagtgtta tgaaagaact ggggaaaata gcacctgatg attaccagat
     2821 aattgggttt gatggtttaa aaacttctgt cgatcaatct tatctagtgt ctacaatagt
     2881 tcaagatatt ggtatgatgg caaaagaatc tgttgcaatg atactgaaaa tgattaagcg
     2941 agaagagatt ctagaaaaac gaatcgtaat tcccacatat ttttggggag ataaaacaac
     3001 aaaaaaaatt taaaaagcgc ttgacaatta atgaaagcgc tgttataata taatcaataa
     3061 atgaaacgtt tcaaaaatag gctagaagct tgtttaaaaa ataaataaaa aatgaaacgt
     3121 ttcaaaaagg agggaaatga tgcgtaaagg tacaatgtta tctgttgttg cggggctatc
     3181 gttagctata cttgcaggtt gtagtggagg aactaactca aaacaagcga gttcttcaaa
     3241 tgatattaaa gtctgggtac aattctctga cgaaacaaat gaaggaaaag cttggcaaaa
     3301 agttgttgat aactttaatc aatcaggaaa aagtaagtac aaggttgtaa ctgagtatat
     3361 tcctcgtagt ggtagtggtg gaggatatga agacaaggtt aatgctgcta ttacgactaa
     3421 tagtcttcca gatgttatta cccttgatgg accaaatacg gcagcttatg caaaatctaa
     3481 agtaattact ccgctagatg attatctaaa agataataat atggatgatg ttttggacag
     3541 tattaaacaa cagggaactt ataatgggaa attctatgca tttggatttt ctgaatcgaa
     3601 tgttggtgtt tattacaata aaaaaatgtt caaagaggcc ggaattgcgg aatcagagct
     3661 tccaacgcta gaaaagccat ggacatggga cgaatttaat acgattgcta aaaaattgaa
     3721 agatcattat aacaaaccag caattgattt tcgtattaat tcaaacgatg aaatgttgcc
     3781 atatgcttat atgccgttga tttggtcaaa taatggttct gtcgtaaacg aagatggaac
     3841 aaaggcagaa ggatacttca actccaaaga gagtgtagaa gcagttcaat tcattcaaaa
     3901 tcttgtaaaa gaaggctata caactgttag tccagtcgaa aaaggttttg aaacaggaga
     3961 gtatccaatg cttttgagtg gttcttggac gattgctgac atgaatacaa actacaaaga
     4021 tattgatttt ggtatccttc cttacccagt atctagtaag acgaaaaaat tagtatcccc
     4081 ttcaggtagt tggcaattag ctgtgacgac aaaatctgat aaaaaagagg ccgcatctga
     4141 atttgttaaa tttgctacaa atacagaatc aagtgaaatt attagcttgg ggaattcggt
     4201 ccttccaatt cgtaaatcta caattgaaaa tatcaaagat aaagtatccg aaccaatgcg
     4261 tttcttgatg gaacaaaatt caaaaacagc tcatgctcgc ccagttgttg tagcatatcc
     4321 tcaggtttct cgagcttttc aacaagcaat gcaagatatt agctattatg aagaaaatcc
     4381 aaatgtgcaa aaagtcttgg atactcgtac aaaagaaatg caaactgcta ttgatcagtc
     4441 actcaaataa tctgtaaaaa agaaggtgga aggaaaatgt ttggaactac cttccccttt
     4501 cttgttaata gcctagtttg atatatatga ttaaaggaga tggatatgag taaagaaact
     4561 gttgtggata caaaaagacg tgaaaaaata aaggataaca tattaggtta tagtttttta
     4621 gctccagctt taattttatt aggtatcttt ttagtaattc cagttggaat ggtcatttat
     4681 tacgctttta cagattatta tttgttgaca ccagatgaaa gaaaatttgt tggacttgaa
     4741 aattttattc gattaacaaa agatccgatt ttcttaaaga gcttcttgaa tactttgaaa
     4801 tttgttgttt ggattattcc agttcaattg ggagcggcct taggaatggc tttgattgtc
     4861 aataaaaagc gaaaaggaaa tatgtttttt aaagtggctt tttttgctcc agttgtcatg
     4921 tccttggtag ttatttctat tctttggctt tatcttttaa atccaaatag tggcttatta
     4981 aatgctattt taaataaggt aggtattgct tctcaacctt tcttgactag tcctaaacaa
     5041 gctatgtatg caattgtttt tgtttctgct tggcagggtg caggttatca gatgctttta
     5101 tttttaggag gaatgcagaa tattccacaa gatgtctatg aagctgctga attagatgga
     5161 ttctcaaaat gggctcagtt tcgttatatc acgatgcccc tactaaaacc aacagccctg
     5221 tttgtattgt taacaacttt aatttctgct tttaagctga ttgtacaacc aatggttatg
     5281 acgcaaggtg ggccattaaa ctcaacaatt actatggtgt actatattta tcaacaaggt
     5341 tttactgatc gtcttgtagg atattctagc tcaatcgctt tagtatttac aacgttaatt
     5401 ggtatgatta gcttagtaca acgtcgcgtt ctgaaggagg atgactaaga tgaaacgatt
     5461 taaaccaaca acaatcttag aatatattct gttaacttta ttggcaggac tcttcctttt
     5521 tcctatggtt tggatggtag tttcagctat gaagccagaa gcggatgttt ataaaaattt
     5581 gactagttgg caagccttct taccaagttt aaatcccgct gattggttta aaccttatca
     5641 ggaagtattt gagcgcttta gtatttttac atatctaggg aacagcattt tttatgctgg
     5701 aacgtttgct attggttcta ttattgtcaa tgcactggcc ggtttcgctt ttgcaaaagt
     5761 caatttttca ggtaagaaaa ttttatttgg tttcttactt gctttactta ttattccagt
     5821 ggaaactgtg ttaattccac aatttaccat tatcaattcc ttaggtttgg tcaataatcg
     5881 tcttgcagtt attattccag gattggcgag tgtatttaat atttacttat ttaggaattt
     5941 ctttattgca attccagaag agattcttga gtctgcaaag atggacggag caagtatcgt
     6001 tagaattttc tttagaatta tgcttccaat gtctaaacct gcagttgcta cagttggtgt
     6061 tttatcattt atttcaagct ggaatgatta tatctggcca ttgatggttt tgacagattc
     6121 ttctaaattt tcaatgcagg ttgcaattac aactattaat acaactcaac cagtttatat
     6181 caatcaggta atggctgtat taactatttc aacgattccg ttgattttgg tctatgtagt
     6241 cgctcagaaa tatattgttc aaggtctggg tggttccgga actggaataa aataggatat
     6301 acttatgata aataaaacat ttacagtaga aaaagccaat cgttttatag cagaaaataa
     6361 acatctcgtt aatactcaat ataagcctga agaacatttt tcagctgaga ttggttggat
     6421 caatgatcca aatggatttg tctattttcg tggagaatac catctctttt atcaattcta
     6481 tccatatgat agtgtttggg ggcctatgca ctggggacat gctaaaagta aggacttggt
     6541 gacttgggag cacttgccag tggcacttgc tcctgaccaa gattatgacc gaaatggttg
     6601 tttctcaggc tctgccattg tcaaggatga tcgcctctgg ctcatgtaca ctggacatat
     6661 cgaagaagaa accggtgtcc gccaagtgca aaatatggca ttttcagatg acgggattca
     6721 ctttgaaaag atttcccaaa atccagttgc aactggatca gacttgccag atgagttgat
     6781 tgctgctgat ttccgtgatc caaaactctt tgaaaaagat ggacgctatt actccgtagt
     6841 agctgccaaa cataaggata atgtgggctg tatcgttcta ctagggtccg ataacctagt
     6901 agaatggcag ttcgaatcca tctttttaaa aggggtagaa caccaaggct ttatgtggga
     6961 atgcccagat tacttcgagt tagatgggaa agattgcctt attatgtcac ccatgcgtta
     7021 tcagcgtgag ggagactcat atcataacat caactcatcg cttttgttca cgggtaaggt
     7081 agattgggga gaaaaatgtt ttatcccaga atcagttcaa gaaattgatc atggccaaga
     7141 cttctatgcg cctcaaacat tgttggacga tcaaaatcgt cgtatcctga ttgcttggat
     7201 gcagacatgg gggcgtaccc ttccaaccca tgaccaagaa cacaaatggg catgtgccat
     7261 gactttacct agaattttaa gattggaaga tggcaaacta agacaattcc ctgttaaaaa
     7321 aggccaatat caaatccaaa tagataaaga ttgtcattac cacttaggaa atgatataga
     7381 ttatcttgaa tttggttatg atagtaatgc gcagcaagtt tacattgatc gtagccatct
     7441 tattcaaaaa attctaggtg aagaagaaca ggacactagt cgacggtatg tagatattga
     7501 agctaaagaa ttggaagttg ttctagataa aaattccatc gagatttttg tcaatcaagg
     7561 tgaagcaagc ttgactgcaa cttattactt aacggtgcca gctgagctat cacgaattga
     7621 ttaaaaatta agttatttct cctaaagaaa aagttctctt tctaaaatag tggaaagagg
     7681 actttttgtg ttttgggtat ataagcttag tttatggtat ttgtaaaatt ggtgttggat
     7741 tatgatttaa gctagttttc taaagaattt gaaaaaaatt ttatttaagc aaaaaaaaac
     7801 cttggttcca aggcttttcc tgttgtattt atatgccccc tacagggatc gaacctgtga
     7861 cccacggatt aagagtccgc tgctctgcca gctgagctaa ggaggcaaag aaaaaagctg
     7921 tattggtgcc gaaacttcac ggtttgtatt gaacccgcgc aattaagcag gtgggcaact
     7981 cgctctaact gaagctgttt ccgtgtgaga cggcctacat gctgttagaa gacttttgtt
     8041 tccctaataa tacaaaaaat agtcggtcaa cacttaagtg tgaagtcgta caccacagcg
     8101 tttctatact tatatgatac cactttttca aaaaaaatca agaggaaagt gcaatttttt
     8161 gaaaaggatt tcagattttt cgcaaacggt cgatagcttc ctttctttga gccaaagccc
     8221 gttcatattt accagtatct tctgcttgga aatagtgatg attacgaatt ttttctggca
     8281 gatagtcttg cttgacccaa tttccaggat agttgtgtgg atagagatag tcttgggcat
     8341 tccccagttc cttgcttcca ctgtagtgcc catcacgtag gtgtcgcgga ataggcaagt
     8401 gccctgatgt tttgaggtca gcaagtgcct tatccatagc tacataggct gagttggatt
     8461 ttggagaaag ggccaaatca atcacgacat tggcaatgag aatgcgggct tctgggaacc
     8521 caatcttctg ggcagcatcc agagcagtca cggtatgaat ctgggcctca ggattggcta
     8581 agccgatatc ttcataggcg ataacagtca agcgacgagc gagactaggc agatccccag
     8641 cctcaatcaa gcgggcagta tagtggagac tggcatccac atctgagcca cgaatagact
     8701 tttgcagggc agatagaaca tcatagtgac cgtctccatc cttgtccata gtgatgtagc
     8761 ttctctgaag actattttcc atgatgtcta aggtgatgtg gcgaatgccc tcgtcattct
     8821 caggggtaga gagaacagct aagtccagtg agttaaaggc agagcgaagg tctccgtttg
     8881 tagaggttgc gatgaaatcc agcgcatcct catctagttc tattggaaaa tcaaaaccac
     8941 gttcagggtt acttagagct atctgcaggg cctctttgac gtcttggtta gacagaggtt
     9001 ccaactcgaa aatttgaact cggctacgaa tggcaggagt gacagagaag aaaggatttt
     9061 cagtcgttgc tccaatcatg atgaccagtc cactttccaa gagaggcaag aggaagtctt
     9121 gcttggtctt atctagtcga tgaatttcgt ctagcaatag gacgagacca ccagaaaatt
     9181 tagcttcttc cgagatttct tgcagtcgct ttttactatc aactgtcgca ttgaaagttc
     9241 gaaaggcata cttggtcgtt ccagcgatgg cagaggcaat actggttttg ccgattccag
     9301 gagggccata tagaatcatg gaggacaggc ggttggcttc caccatgcgg cggatgattt
     9361 ttccaggtcc gaccagatgc tcctgaccga tgacctggtc gatggtttta gggcgcatgc
     9421 gaagcgcgag attgtctggc atagcagtcc tttctagcgt ggatttgagt agaatgactc
     9481 atctactata tcttactatg tccattctag cctattagtt gtgatatttc aatggttttg
     9541 taataatcag ggagtgagat agaatctttt ttactattta atttaatgag gagaggtatc
     9601 agcatgagag atttgatttt ccttaaagct caaaatagga tagttgagcc taaagaagtg
     9661 gaagtgctga cttgagaaat aatattgctg aatgtcattg tatgaactat aatgaaaaga
     9721 gaggtgataa gtaatggaaa tgatggacca agtcaggaaa ttttgatttt tacaaaacaa
     9781 attcgtcatt ggattcttag tgatcaagtt atttcaggga aaagaaaact tttcttccgg
     9841 gaagatactc caaaagagat tttagatttg tacgaaaaca ttaaatctaa acttgatttt
     9901 gcttaccaat aagtttattc taataatggg ttgaaaaaat atgaaaaata gaataattga
     9961 tgtttttgaa gtagtaaatc gcatccttgt aataactgtt gaaaatcctg atttcgaaga
    10021 cttgagagtt aatcatactc aatgaaaatc aaagagcaaa ctaggaaact agccgcaggc
    10081 tgtacttgag tacggtaagg cgacgttgac gtggtttgaa tttgattttc gaagagtatc
    10141 agtttgtaaa aattggagat aaaaaatata gagtacgcag tgttcctatg attcattcaa
    10201 ctccgcctca atctgtctta gatcgagata cttttacaat tgactataca gatgatgaat
    10261 tgctcgataa agaagcagtt tttactactc attagaaaaa taggtctgaa taaattggct
    10321 tcccttagaa ccacatctag gggcttttat gtataataga ataataagta tcactccttt
    10381 acaatacgtg taacacgtgt tataatggtg ttgtcaggag gtaaaagcgc tatgcctatg
    10441 acacaaaaag agatggttaa actccttacg gcccatggtt ggataaagac tagaggcggt
    10501 aaaggctccc atattaaaat ggagaagcaa ggggaaagac ttatcacaat ccctcatggt
    10561 gagctgaata agtacactga aagagggata agaaagcaag ctgggttgta aaattcagcc
    10621 cctgtttttt gatatggagg tagtgaaatg ttagttacgt atccagcttt attttattat
    10681 gacgacacag acggaacaga agcgacttat tttgtccatt tcccagattt tgaatactca
    10741 gctacacaag gagaggggat ttctgaggct ttggctatgg ggtcggagtg gctagggata
    10801 actgttgcag atttgataga gagtgatgga gagttacctc agccatcaga tatcaatagc
    10861 ttgtctttaa ttgataatga tccttttaaa gatgatgaag atttcgtgtc aacctatgac
    10921 cttgataaat cttttatttc tatggtatct gttgatgtat cagaatacct aggaagtcag
    10981 gaacccataa aaaagacttt gaccatacca aaatgggcag ataagttggg acgagaaatg
    11041 ggacttaact tttctcagac tttgacagac gctattgcag ataagaaagt tcaagcctaa
    11101 gattaagcgt ggtatcgtgg taatagtcaa taaaaaagca cgtccacttg tgctagttac
    11161 tcgcctattg attttataga tttattagcc ctttcgcggg ctttttatat tgatttttat
    11221 gagaaatgaa gaaatcagac ttttaagaaa atcactgata ccaagggttt aaatgaggta
    11281 atatggtata attaggacat aaaataattt tgtggtaaga tggtagtatc tattttagca
    11341 tatttccgag caatcggggc gattaaagag tcgcatagaa agaggacaaa atggcaacat
    11401 acggattttt agatgtttta gaggaagagt tggacaagaa ctttcccttt gactttgaga
    11461 ttagctggga caaacgcaac catgcggtag aagtgagttt tctattggaa gcgcaaaatg
    11521 ctgcaggtgt ggagatggtg gatgaagacg gagaggtttt atcagatgac attctttttg
    11581 aggaagcggt ccttttctac aatcctgcca agtcaacagt caatgaggaa gactatttga
    11641 ctgttattcc ttacctgcct aaaaaaggat tttcccgtga atttttagct tattttgcgc
    11701 ttttccttaa agatactgct gaggttgggc tagatgtcct catggacttt ttggaagacc
    11761 cagaagcaga ggaatttgtc atggaatgga accaagaagt ctttgaagaa ggaaaagttg
    11821 gcttggaaga gggagaattt tatccttatc caagatacta ggagttggtt ggaggtgtta
    11881 tgaagaaaat tgggacttat ttggtttatg tgctagcttt tgtctttatt atgctagctt
    11941 ttgcttgtgg aacaatcgca tttgcagagt tggggtattc cgcagtttta gcctttactt
    12001 ttggttatgc cttcgctctt ctaagcatgt atttaatctt tattcttcat gagctgggtc
    12061 atgctttttg tggctacttg acaggctatc ggctggtggc ttttggatta ggacatttta
    12121 ttttgaccaa aaagtcaggc aggtttcatc ttagtagaac agccattctg aaaaatgttg
    12181 gtgctcaata cattggttta aaagaggatg aaagcgatca aagaatcatc ctgatgcttt
    12241 caggaggctt gatggttcat ctcggcttga tattattggc gatagtgttt ggatttttga
    12301 caagaagctg gtattttgca gggacttgga tttttcttaa tttatctttc ttcctaaata
    12361 acattttgcc agtcgacatc accgatggag caaaaatttg ggaattacta caacaccctg
    12421 aaaataccaa atacgcctac ctggtattga gacattctgc tcaaactttg ctggctcctc
    12481 aagaatatga tttgaaagac tttgttcaag cagttcctga ggatgcacga gggagttttg
    12541 cggatggtgt attaggtatg caaggtgaag tttccatttt ggaagggaag gaagaagtag
    12601 ctaaacagca gtttcaagca ttacttgaga ggacaactac tccgatgatg cagacagttg
    12661 cccaactatc cctgcttcat atcgccttgt tggaaggaga ttttgagcaa gcggagcaat
    12721 atgctagtat tcgacaggtc aaatcgtttc tgtctctcaa actgtccaat cttcaagtga
    12781 tacaagcttg gtatcaattt aaggtaaaga aagatgtaga tcgaactcgt aaggctctca
    12841 agattgctag acagaaaatg gatagtagtc gaatgttgag ggacgagaaa cgctattatg
    12901 aaaacttgtt agcagagctg gaaaaggaaa tgttagaagg aactgaagat ggaactagaa
    12961 atttctgatt tcccaggctg taagattgct ttgttttgtg gggataagct cttgactatc
    13021 ttacgtgatg ataaggcaag tattccctgg gccaatatgt gggaactgcc aggtggtgga
    13081 aagagtgtca gggaaaatct gatatagttt tgtattaaaa gaatatcctt tcaaggttat
    13141 tcttttttaa ttttgtccca aaataattga ctttgtcccg aaaatatagt attgtttgta
    13201 taaggaggaa tgaatcatga aaaaatcaga tgttcttgat ttaataaagt atcattatga
    13261 gggcagagag acagaattta gaaatcaatc catagcaatt gctcggaact tcaataaaca
    13321 tggtgataca caaatagcac aatatattat ggggttaatg tctcaaagtg atagattcat
    13381 gccacaaata gaaaatccta gtgagtattt gactcctgct aaactagata ttggtcctct
    13441 cccattgcct ctttcaatta tgaatgattt aaaaggaata ataaacgctg tcaatcatca
    13501 tattggaata aataaatttt tatttgtggg atctccaggt actggaaaaa ctgaaagtgt
    13561 aaagcaggtg gctagactta ttggcaagga attacttgta gtagatttca gtcacttagt
    13621 agatagtaag ctagggcaaa cagtcaaaaa cttagcaact ctttttaatg aaatcaataa
    13681 tcttcctttc aagcaaaatt atatcatcct atttgatgaa attgattcca tagtgttgga
    13741 tagggttaat cagaatgatt taagagaaat gggacgagtg acttctgcct ttttaaagga
    13801 gttggatagg ctgtcaccag aaattgtatt aattgcaaca acaaatcttt ttgaaaatct
    13861 tgataaagca gttacgagaa gattcgatgc cataattgac tttgaccgtt atactgatga
    13921 agataaagta gaagtagcta ctattatttt aaatgagtta ttaaagcaat ttaagaatgt
    13981 agctagagat ttaaaattat ttaaaaaaat tatcaatagt gccaatgtaa taccgaatcc
    14041 tggtgatttg agaaactcaa taagaacgtc attggcattt agtgacccat cagatccgca
    14101 tgattaccaa aaacgcctgc taagaagttt gcataatggt agaaatttat ctatttctaa
    14161 attatcgaag ctaggtttta ctgttagaga aattgagatt ttgacaggta tttctaagag
    14221 tagtgtatca cgagagttaa gcgaggatta aaatgaatac attattgaca ttacgaggta
    14281 aaagttttac acaaaagtca gcaaagggga ggggaccgat aacgattccc gcagattcta
    14341 ttgttacgct aaaccattta aatgaacttt atacatccct tgaacgagta aaagaatatt
    14401 ggtctaataa cacaatcatt gatggagtac ttattagtgt gtattataat cgtgtcctag
    14461 ctaagagcaa tcgtatcgat ggttttttta atgtgggtgg cggaaatgca attccaaatg
    14521 aaacgattgt gggtgcaaaa tttagtaatg ataagagtag gcatattatt acacactaca
    14581 tttcaaagga agtgttagat aagacaattg agcatactaa aaaagttata acaatattca
    14641 aagattattt tgctagtgct cccatgacga gtatggtgtt ctccgactct tcaaaattta
    14701 atcaaattga ttattctaag tatggtctgt cgaaatcaaa attcaaacaa tacttaagag
    14761 acgcttgctt tgtcaaagga tttggtattg aacaggcaga tatgtctact atacgtaatt
    14821 ctattgtaac aatctacgat gtaaaaacta atctcttaac attacttaaa caacttgata
    14881 ttgatgtttc agaagctaac atcatggacc agacaactgt tttacttgac gaaaaaaata
    14941 ttgagttact actgctaaaa gcaccttatc tagtatcaat gatagtagaa gatttttcta
    15001 gcctgtcacc agagaatttt tataatgatg ggaacacttt ttataataat ctcccttttc
    15061 caactaatga acctattatt ggtgtcatcg atacgttgtt tgatgataga gtttatttca
    15121 atgagtgggt agagtatcat gatttaattt caccagatat tagcaaagga agtcaagact
    15181 ataagcacgg tacagcagtt tcctcggtaa tagtagatgg agctagtttg aatccaaaac
    15241 tagatgacgg atgtggaaga tttagagtca gacattttgg gatatcttta cagagtggtt
    15301 tcaattcctt cacaattatc aaacagatta gagaaattgt gtctcaaaat cctgatatta
    15361 aggtttggaa cctttcgctt ggatcaaatg atgaaattag ggaaaacttt atttctgtcg
    15421 agggttcgtt gttagacgag attcaatttg ataacgatgt aatttttatt attgcaggca
    15481 ctaatgggat tgcccctgat ggacaacgaa aaaagattgg agcaccagca gattcactca
    15541 attcaattat tgtaaattct gttgatttta gcaatcaagt cgtttcttat tcacgcgaag
    15601 gagttgtcct gtctttcttt atcaaacctg atgtttcata ctatggcggg gggaacggag
    15661 acttcataaa tgtttgtgaa ccactagggc tggctcgagt agctgggacc agttttgcgg
    15721 ctccatttat tgctagaaaa atggcttacc tcattcatat tatgggatta agtcgtgaag
    15781 aagcaaaggc tttattaatt gattcagcga taccatggaa tgataaaaaa acattcgcag
    15841 acatttcttt acttggatat ggggttgtgc caatcaaaat agaagatatt ttgtctacac
    15901 ctgatgatga aattaaattt atagtctcag atgtttctag agcatatgaa acttataatt
    15961 atgatttccc agttccaatt tctaaagaac actatccata tgtagcaaag gccactatgt
    16021 gctattttcc aaagtgttct agaaatcaag gagttgacta tactaatacg gaaatgcaac
    16081 ttagtttggg agttttagat aagaaaggca ttaaaacaat taataacgac aatcaatatt
    16141 ctgaaaatgc accaggatat gtgagagaaa agtcggcacg aaatattttt aggaaatggg
    16201 ataatgtcaa acatttagga gaaaaatttt cttctcgtaa aaaagctaag ccgattctga
    16261 atccttctaa tcctcaatgg ggaatgagtg taaaaacaat tgaacggtta agaaatgatg
    16321 atggttatgg tattcgtttt ggagtagttg ttactctaaa ggagttgaat ggtgtcaata
    16381 gaatcgaaga ttttattcaa caagccgaat tacgcggttg gctagttaat agattgcaag
    16441 tagaagctca agtagacctc tttaatagtt taaatgaaga aattgaattt gaatagtgga
    16501 tattttatcc ttattctaga tcttaggaac acaagagggc aaagatatga atattactta
    16561 tatagttgga aatggtttgg atttgcaata tggtttgaaa acaagatata aagatttcta
    16621 tgaatttcaa aataggactt acataagtag gaaagagaac gaggaagaat attcaaatct
    16681 catttatgag tctctatttt ctgatacagt aaatgattat gaaaattggt cagattttga
    16741 attgtcaatt ggtaaattaa caaaagataa cgacctcatc tcctcaagta tagaaataaa
    16801 ggagaaattt atagatgatt ttagtgaagt agttgatgat ttaagagaat atctacgcat
    16861 acaacaagaa aaaaatcttg agaaaggtaa tgcaattgac tttataagca ctctagataa
    16921 tatgaggacc tctctccctg taattaatca acctgctatc gataaaaaat ataatgaaaa
    16981 tctatatcaa cacgatatcg tgaatatatt aactcttaat tacacaaatg taatcgataa
    17041 attatataat gagtcagcaa aatcatttag caatcaatta cgaactaata attataaatt
    17101 tcacattgcg cctccaattc atgcacatgg aacggtagat atttgcacag ttttaggagt
    17161 tagtgacgag acacagattt caaatagttt tgatgaagaa caaaaagaat ccttaataaa
    17221 aaatttagtt ttgaagaact atagagaaaa tatggatgtt aaaaatagcg atattataaa
    17281 aaattctgac atcataattc tttatggggt ttctttggga gagactgatg ggtatatctg
    17341 gaatcagatt gctgaacaat caatcagaag ttctgttcct gtcataattt accattatgt
    17401 acctcatttt gatgcaggaa accccactag agtaaaacgc ttatatagaa atgtagaaga
    17461 caaattcata caaaatagtg gaattgattt agagttagag aagaaattaa gagataacct
    17521 tattgttgtt attggaaaga ctatttttaa tctgatggaa aggtaagcaa aatacataat
    17581 ggaaacatgg caagagttaa aagttacagt gaagcgtgag ggggaggaat tggtttccaa
    17641 tctcttgatc gagctgggag cgcaaggcgt tgcgattgaa gacagcatgg actatgtggg
    17701 aaatgttgac cgcttcggcg agattttccc agaggttgag cagcaagaag aaatcgtagt
    17761 gacagcctat taccctgata cggttgatgt agcaacggtt gagtcagatt tgcaggctcg
    17821 tctagcagaa ttgacagatt ttatggattt gggtgaagtc aagatgggga cgactgcctt
    17881 ggctgaggaa gactgggcag acaactggaa gaaatactat gagccagctc gtatcactca
    17941 tgatttgacc atcgttccct cttggacaga ctatgaggcg actgcgggag aaaaaattat
    18001 caagctagat cctgggatgg cttttggtac tgggacccat ccaactacca agatgagcct
    18061 ctttgccttg gaacaggttc ttcgtggtgg cgaaacggtg ctagatgtgg ggactggttc
    18121 aggggttctc tctattgcca gctcgcttct gggggctaaa gaaattttcg cctatgacct
    18181 ggatgatgtg gcggttcgtg tggctcagga aaatattgag ctcaaccctt gtatggaaaa
    18241 catccatgta gcagcaggag acttgcttaa gggtgttgag attgaggcag atgtgattgt
    18301 agctaatatc ttggcggata tcctcgttca tctgacagac gatgcctatc gtttggttaa
    18361 ggacgaaggc tacctgatca tgagtgggat tatcaaggac aagtgggaca tggtgcgcga
    18421 gtcggctgag ttatctggat ttttccttga gacccacatg attcaggggg aatggaatgc
    18481 ctgtgtcttc aagaagacca aggatatctc tggtgtgatt ggaggctagc atgcagcagt
    18541 attttgtaaa aggcagtgct atctctcctg tcactatcga ggacaaggaa accagtaagc
    18601 atatgtttca ggttatgcgc ttgaaagaag aggatgaggt taccttagtc tttgatgatg
    18661 gcatcaagcg cttggcgcgc gtgctggata tggaaaatcg tcagtttgag ttgatccaag
    18721 aattaaatga caatgtggaa ctaccagtcc aagtgaccat cgcatctgga tttcccaagg
    18781 gagacaagct ggagttcatc gctcaaaaag taaccgaact gggtgctagc caaatctggg
    18841 cctttcctgc agattggtca gttgccaagt gggatggcaa gaaattggat aaaaaagttg
    18901 aaaaactaga aaaaattgcc cttggagcag ccgagcaaag caagcgtaat attgtaccaa
    18961 gtattaaact tttcgagaaa aaagcagatt ttctagctca gctggaccag tttgactcta
    19021 tcatagtagc ctatgaagaa tcagctaaag aaggagaagc cgctgcgctt ctgcaagcag
    19081 tcactggtct tgaaacagga gccaaactgc tctttatctt tggtccagaa ggcggtctct
    19141 cacctgtaga aatcgaaagt tttgaagcta agggagccgc tttggtaggc ctaggtcctc
    19201 gtattttgcg agcagaaaca gcaccgcttt acgccttatc agcccttagt gttttagtag
    19261 aattagagaa ataagaggaa gaaaatggaa caaaaacacc gttcagaatt tccagagaag
    19321 gaactctggg acttaacagc cctataccaa gactgtgagg atttcttgcg tgcaatcgag
    19381 aaagctcgtg aagacatcaa ccaatttagc cgtgactaca agggtaatct tcatactttt
    19441 gaggatttcg agaaggcctt tgcggaattg gaacagatct acattcagat gagccatatt
    19501 ggcaactatg gttttatgcc tcagacgacg gactatagca atgacgaatt tgccaatatt
    19561 gcccaagctg ggatggaatt tgaaacagat gccagcgtag ccttgacctt ttttgacgat
    19621 gccttggtgg cagcagacga ggaagtcttg gaccgtttgg gtgaattgcc tcacttgacg
    19681 gcagctattc gtcaggccaa aatcaaaaaa gcccactatc taggggctga tgtggagaag
    19741 gccttaacca atctcggtga agttttctat agtccgcagg acatttatac taagatgcga
    19801 gctggggatt ttgaaatggc tgactttgaa gcccatggca agacctataa aaacagcttt
    19861 gtcacctatg agaatttcta ccaaaatcac gaggatgctg aggttcgtga gaaatccttc
    19921 cgttccttct cagagggact tcgtaagcac caaaatacgg ctgcagcagc ctatctggct
    19981 cagatcaagt ctgaaaaact cttggctgat atgaagggat atgactctgt ctttgactat
    20041 cttctagctg aacaagaagt ggaccgtgtc atgtttgatc gccagattga cctcatcatg
    20101 aaggactttg caccagtcgc tcagagatac ctcaagcatg ttgccaaggt aaatggtctt
    20161 gaaaagatga cctttgcaga ctggaaattg gacttggaca gcgccctgaa tcctgaagtg
    20221 actattgacg atgcctatga tttggtcatg aagtcggtag aacctttggg gcaagaatat
    20281 tgtcaggaag ttgctcgtta ccaagaagag cgctgggtgg actttgctgc taacagtggc
    20341 aaggattccg gtggttatgc ggcggaccca tatcgcgtac acccttatgt actcatgagc
    20401 tggacaggcc gtttgagcga tgtctatacc ttgattcatg aaatcgggca ttctggtcaa
    20461 ttcatctttt cagacaatca tcaaagttac ttcaatgccc atatgtcgac ctactatgtt
    20521 gaagcaccgt caaccttcaa tgaattgcta ctcagtgatt acttggagaa ccagtctaat
    20581 gacccacgtc aaaaacgctt cgctctggct catcgcttga cagacaccta cttccataac
    20641 tttatcaccc acctcttgga agccgccttc cagcgtaagg tgtatacatt gattgaagaa
    20701 ggggagacct ttggagcaag caagctcaac agcattatga aggaagtttt gacggatttc
    20761 tggggagatg ctattgaaat tgacgatgat gcaactctga cttggatgcg ccaagctcac
    20821 tactatatgg gcttgtatag ttacacttac tcagcaggac tagttatctc gactgctggt
    20881 taccttcatc taaaacattc tgaaactgga gctgaagact ggctcaatct cctcaaatca
    20941 ggtggtagca agacaccact tgagtcagcc atgattatcg gtgctgatat ttcaacagac
    21001 aaaccactcc gtgataccat ccaattcttg tctgacacag ttgaccagat tatctcctat
    21061 agtgctgagt tgggagagta ggggaataga aaaatttttt agaatgatgt ttatgggctt
    21121 gttaagcgtc attctatttg tcttagttgt agctattttc aaaaatgtcg ttgaaggtcg
    21181 tgatgttaaa tttgaactta ctgtagaact ggtattgata gttatttacg tcattttata
    21241 tcagattgta tttaattgag aattcaatat tgagtcattt aagactgcct ttttgaacag
    21301 ttgctagaaa tgtagaggta ttgaccatgt atcaagattt actaagaaaa atagcagaag
    21361 aaaaaccaaa ttataaccag gaagaaatcc agtggttgtt tgatcatttg ggaaatcctt
    21421 ctccagaaat tcgtaatgtc cttttaaatc aaggcttgca ctatctttca aaagaaaagg
    21481 atacaagggg tttctcaagt cagtatggtt gggttcacgc ttttgcacat ggagccgatt
    21541 tactgacaga ggtggtttgt catccagact ttcctaaaaa cagagttcat gaagtatttg
    21601 atatacttgg ccaactattt aaaagaatgt cgattcgctt tacagatgat gaggattggc
    21661 gtttagcaag agtgatctat gaacctattt tacaagggaa gttggagcaa gaacaagtag
    21721 cttcttggat aaaaactgtt gattttccga tagaagaaag ggaggatttt tacaaatttt
    21781 ccaactttag atcctgtctg gtggaagtct atgtccaact tgaccagaga aatagtttac
    21841 aagatgacct gaaagaagct atccagtctt ttcaatacta gggattagct aatagttcta
    21901 tgattttcaa aaaatttcca atcaattttc ttgaaaccct ttcctacttt tgatagacta
    21961 gtatctagtt tttgaaaaaa ggagaaagaa aatgaaaaaa tttgttgctg agttaatcgg
    22021 tacgttcatg cttgtattcg tcgggacagg agctgttgtt tttggaaatg gtcttgatgg
    22081 ccttggtcac cttggaatcg cctttgcctt tggtttggca atcgtggtgg cagcctactc
    22141 aatcggaact gtttcaggtg ctcacttgaa cccggctgtt tcgattgcta tgtttgtaaa
    22201 caaacgtttg tcatcttcag aacttgtaaa ctacatcctt ggtcaggttg ttggagcttt
    22261 catcgcttct ggcgctgtct tcttcctctt ggctaactca ggtatgtcaa ctgctagtct
    22321 tggtgaaaat gccttggcaa acggtgtcac tgtctttggt ggtttcttgt ttgaagtcat
    22381 cgcaactttc ttgtttgtat tggttatcat gactgtgact tcagaaagca agggcaatgg
    22441 cgcgattgct ggtttggtaa tcggtttgtc attgatggcg atgattcttg tcggattgaa
    22501 gattactgga ctttcagtaa acccagctcg tagcttggca ccagctgtct tggtaggcgg
    22561 cgcagccctt caacaagttt ggattttcat ccttgcacca atcgctggtg gagttcttgc
    22621 agcccttgtt gcaaaaaatt tccttggaac agaagaataa ttgaaactca aaaagccttg
    22681 ctcctcatct tgaggaacag ggctttttcg tatgatactc ttcgaaaatc tcttcaaacc
    22741 acgtcagctt catcttgccg taggtatggt tactgacttc gtcagttcta tccacaacct
    22801 caaaacagtg ttttga
//
LOCUS       DBEJAU010000033        22810 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC323 isolate 683620
            SAMN38261939-rid24807223.denovo.033, whole genome shotgun sequence.
ACCESSION   DBEJAU010000033 DBEJAU010000000
VERSION     DBEJAU010000033.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261939
            Sequence Read Archive: SRR26833919
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 22810)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 22810)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576303.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576303.1
            Genome Coverage       :: 154x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/19/2025 01:05:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,121
            CDSs (total)                      :: 2,078
            Genes (coding)                    :: 1,943
            CDSs (with protein)               :: 1,943
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 36
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 72 of 135
            Pseudo Genes (incomplete)         :: 63 of 135
            Pseudo Genes (internal stop)      :: 51 of 135
            Pseudo Genes (multiple problems)  :: 46 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..22810
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261939-rid24807223.denovo.033"
                     /strain="GPSC323"
                     /isolate="683620"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            complement(52..276)
                     /locus_tag="ACL29Z_001371"
     CDS             complement(52..276)
                     /locus_tag="ACL29Z_001371"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000571861.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="accessory secretory protein Asp5"
                     /protein_id="HGR0069670.1"
                     /translation="MIDILIVLAIILSLALIVLVTIQPRQNQLFSMDATSNIGKPSYW
                     QSNTLVKVLTLLVSLALFVLLLTFMVITYK"
     gene            complement(281..460)
                     /gene="asp4"
                     /locus_tag="ACL29Z_001372"
     CDS             complement(281..460)
                     /gene="asp4"
                     /locus_tag="ACL29Z_001372"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001287962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="accessory secretory system protein Asp4"
                     /protein_id="HGR0069671.1"
                     /translation="MSEEDLFYKDVEGRMEELKQKPIKKEKETRGEKISKTFSLLLGL
                     MILIGLLFTLLGILR"
     gene            complement(462..1799)
                     /gene="gtfB"
                     /locus_tag="ACL29Z_001373"
     CDS             complement(462..1799)
                     /gene="gtfB"
                     /locus_tag="ACL29Z_001373"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000571772.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0031647 - regulation of protein stability
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="accessory Sec system glycosylation chaperone
                     GtfB"
                     /protein_id="HGR0069672.1"
                     /translation="MIELYDRYSHESRDLHESLVATGLSQLGVVIDADGFLPDGLLSP
                     FTYYLGYEDGKPLYFNQVPVSDFWEILGDNQSACIEDVTQERAVIHYADGMQARLVKQ
                     VDWKDLEGRVRQVDHYNRFGACFAKTTYDVLGQAIMTSYRDVDQKEVILENHVTGDIL
                     LTLPGQSMRYFANKVEFITFFLQDLEIDTSQLIFNTLATPFLVSFHHPDKSGSDVLVW
                     QESLYDAIPGNMQLILESDNVRTKKIIIPNKATYERALELTDEKYHDQFVHLGYHYQF
                     KCDNFLRRDALILTNSDQIEQVEAIAGALPDVTFRIAAVTEMSSKLLDMLRYPNVVLY
                     QNASPQKIQELYQLSDIYLDINHSNELLQAVRQAFEHNLLILGFNQTVHNRLYIAPDH
                     LFESSEVAALVETIKLALSDVDQMRQALGKQGQHANYVDLVRYQETMQTVLGG"
     gene            complement(1792..3303)
                     /gene="gtfA"
                     /locus_tag="ACL29Z_001374"
     CDS             complement(1792..3303)
                     /gene="gtfA"
                     /locus_tag="ACL29Z_001374"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016757 - glycosyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="accessory Sec system glycosyltransferase GtfA"
                     /protein_id="HGR0069673.1"
                     /translation="MTIYNINLGIGWASSGVEYAQAYRAGVFRKLNLSSKFIFTDMIL
                     ADNIQHLTANIGFDDNQVIWLYNHFTDIKIAPTSVTVDDVLAYFGGEESHREKNGKVL
                     RVFFFDQDKFVTCYLVDENKDLVQHAEYVFKGNLIRKDYFSYTRYCSEYFAPKDNVAV
                     LYQRTFYNEDGTPVYDILMNQGKEEVYHFKDKIFYGKQAFVRAFMKSLNLNKSDLVIL
                     DRETGIGQVVFEEAQTAHLAVVVHAEHYSENATNEDYILWNNYYDYQFTNADKVDFFI
                     VSTDRQNEVLQEQFAKYTQHQPKIVTIPVGSIDSLTDSSQGRKPFSLITASRLAKEKH
                     IDWLVKAVIEAHKELPELTFDIYGSGGEDSLLRDIIANHQAEDYIQLKGHAELSQIYS
                     QYEVYLTASTSEGFGLTLMEAIGSGLPLIGFDVPYGNQTFIEDGQNGYLIPSSSDHVE
                     DQIKQAYAAKICQLYQENRLEAMRAYSYQIAEGFLTKEILEKWKKTVEEVLHD"
     gene            complement(3315..5687)
                     /gene="secA2"
                     /locus_tag="ACL29Z_001375"
     CDS             complement(3315..5687)
                     /gene="secA2"
                     /locus_tag="ACL29Z_001375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000489793.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015450 - protein-transporting ATPase
                     activity [Evidence IEA];
                     GO_process: GO:0015031 - protein transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="accessory Sec system translocase SecA2"
                     /protein_id="HGR0069674.1"
                     /translation="MFRRLGQDFQLRKVKKILKQINALKGKMSSLSDQELVAKTVEFR
                     QRLSEGESLDDILVEAFAVVREADKRILGMFPYDVQVMGAIVMHYGNVAEMNTGEGKT
                     LTATMPVYLNAFSGEGVMVVTPNEYLSKRDAEEMGQVYRFLGLTIGVPFTEDPKKEMK
                     AEEKKLIYASDIIYTTNSSLGFDYLNDNLASNEEGKFLRPFNYVIIDEIDDILLDSAQ
                     TPLIIAGSPRVQSNYYAIIDTLVTTLVEGEDYIFKEEKEEVWLTTKGAKSAENFLGID
                     NLYKEEHASFARHLVYAIRAHKLFTKDKDYIIRGNEMVLVDKGTGRLMEMTKLQGGLH
                     QAIEAKEHVKLSPETRAMASITYQSLFKMFNKISGMTGTGKVAEKEFIETYNMSVVRI
                     PTNRPRQRIDYPDNLYITLPEKVYASLEYIKEYHAKGNPLLVFVGSVEMSQLYSSLLF
                     REGIAHNVLNANNAAREAQIISESGQMGAVTVATSMAGRGTDIKLGKGVAELGGLIVI
                     GTERMESQRIDLQIRGRSGRQGDPGMSKFFVSLEDDVIKKFGPSWVHKKYKDYQVQDM
                     TQPEVLKGRKYRKLVEKAQHASDSAGRSARRQTLEYAESMNIQRDIVYKERNRLIDGS
                     RDLEDVVVDIIERYTEEVAADHYASRELLFHFIVTNISFHVKEVPDYIDVTDKTAVRS
                     FMKQVIDKELSEKKELLNQHDLYEQFLRLSLLKAIDDNWVEQVDYLQQLSMAIGGQSA
                     SQKNPIVEYYQEAYAGFEAMKEQIRADMVRNLLMGLVEVTPKGEIVTHFP"
     gene            complement(5680..6120)
                     /gene="asp3"
                     /locus_tag="ACL29Z_001376"
     CDS             complement(5680..6120)
                     /gene="asp3"
                     /locus_tag="ACL29Z_001376"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006886 - intracellular protein transport
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="accessory Sec system protein Asp3"
                     /protein_id="HGR0069675.1"
                     /translation="MIITQRQSIYWGEVGGTYMYGTTVSYYLDKSVRLYNPLLPSGEI
                     LKTWFSSVNYQAARTQPQLPLLKRKQEYQLSLVFDCQPENGVYTKITFFDRYGDILEK
                     KVEKAKDFIFTYPEDSYTYQVSLLSAGFESLTFYHFSIKEIRSV"
     gene            complement(6117..7652)
                     /gene="asp2"
                     /locus_tag="ACL29Z_001377"
     CDS             complement(6117..7652)
                     /gene="asp2"
                     /locus_tag="ACL29Z_001377"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000032116.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006886 - intracellular protein transport
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="accessory Sec system protein Asp2"
                     /protein_id="HGR0069676.1"
                     /translation="MSKELNILQIGLANWENHYDIPENMSWYYFYPNSSKTLREIIEK
                     EDINRFHAVLIEDGQYSRDLFSYVKYFEPYTLFYNQNLQINDREVVDFLKKRCAQAID
                     FLSPQQLINDLSKSLFGGGYGDKLFPPTIQVNPNFTGAISYQGLDYVSLEGEFGQDFA
                     QLAYWAYNIMVQKTLPIELWLEYEKEGNCDFRLVIRKMWSGSVDDFFEEVIVSEKDLE
                     QALFMDSRDGDYFLSISVEARGRGTIKLGNLHQRWSRKQFGKFVLGGNILHDSKRDEI
                     NYFFHPGDFKPPLTVYFAGYRPAEGFEGYFMMKTLGCPFILFSDPRLEGGAFYLGTDE
                     LEGKVKDTITHYLDYLGFDHKDLILSGLSMGTFPALYYGASFEPHAIIVGKPLANLGT
                     IASRGRLDAPGVSNLAFDCLIHHTGGTSSQDMTELDQRFWKIFKQANFSKTTFGLSYM
                     KDEEMDPQAYEQLVSYLCNTGAKILSKGTAGRHNDDTDTNISWFLHFYRMVLETGFGR
                     EKR"
     gene            complement(7636..9216)
                     /gene="asp1"
                     /locus_tag="ACL29Z_001378"
     CDS             complement(7636..9216)
                     /gene="asp1"
                     /locus_tag="ACL29Z_001378"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000291149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006886 - intracellular protein transport
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="accessory Sec system protein Asp1"
                     /protein_id="HGR0069677.1"
                     /translation="MYYFIPAWYGSERTWHADITPWYFSHFRLEFDDTFHQIRLFQEQ
                     DIDSRLLVLAYQPHLRYFLYRHGVLETDTYSVFDVMQDFHNLHTQVLSIRDIEWDDDC
                     EFIYSPFTIIVQKNGKKFAKVEHGVEGFISDIQYFEPNVQIHMHHIMDDRGFISSIIF
                     FEDGQAAYQEYLNPKGVWQFRERLKEGGQVEVNPILGYRFKMLTYQNMGDLVAEFFEN
                     YLQTYVKDQDIFMLPSHSHHDQLVLDRLPSTNPKLLSLFIGRNPQDTFRDLDVTFEKS
                     DLILVDREDSLRLLQELYPERMHQCYHLSSFDTRLRLGRSQTKKESIIYFQLDFEQGI
                     DNQALLQVLSFVAENKDTEVIFGAFAASQEQMNEVEGIVESFIQENIQSENLGKAIDY
                     GDAENPLEENQHQDLRLQFVNLNDELDLIKTLEFVRLIVDLNRHPHLYTQIAGISAGI
                     PQINLVETVYVEHLKNGYLLTDVTEFSKAAHYYTDRLKEWNESLIYSIDKIKEHTGQQ
                     FLGKLEKWIEEVKNVKGT"
     gene            complement(9226..10443)
                     /gene="secY2"
                     /locus_tag="ACL29Z_001379"
     CDS             complement(9226..10443)
                     /gene="secY2"
                     /locus_tag="ACL29Z_001379"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000161857.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="accessory Sec system protein translocase subunit
                     SecY2"
                     /protein_id="HGR0069678.1"
                     /translation="MTKIYSSIAVKKGLFTLFLLFIYVLGSRITLPFVDLNTKDFLGG
                     STAYLAFSAALTGGNLRSLSIFSVGLSPWMSAMILWQMFSFSKRLGLTSTSIEIQDRR
                     KMYLTLMIAVIQSLAVSLRLPVQSSYSAILVVLMNTILLIAGTFFLVWLSDLNASMGI
                     GGSIVILLSSMVLNIPQDVLETFQTVHIPTGIIVLLALLTLVFSYLLALMYRARYLVP
                     VNKIGLHNRFKRYFYLEIMLNPAGGMPYMYVMSFLSVPAYLFILLGFIFPNHSGLAAL
                     SKEFMIGKPLWVYVYISVLFLFSIIFAFVTMNGEEIADRMKKSGEYIYGIYPGADTSR
                     FINRLVLRFSVIGGLFNVVMAGGPMLFVLFDEKLLRLAMIPGLFMMFGGMIFTIRDEV
                     KALRLNETYKPLI"
     gene            complement(10500..11405)
                     /locus_tag="ACL29Z_001380"
     CDS             complement(10500..11405)
                     /locus_tag="ACL29Z_001380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001292324.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HGR0069679.1"
                     /translation="MSELISVVVPIYNTGKYLVECVEHILKQTYQNIEIILVDDGSTD
                     NSGEICDAFMMQDNRVRVLHQENKGGAAQAKNMGISVAKGEYITIVDSDDIVKENMIE
                     TLYQQVQEKDADVVIGNYYNYDESDGNFYFYVTGQDFCVEELAIQEIMNRQAGDWKFN
                     SSAFILPTFKLIKKELFNEVHFSNGRRFDDEATMHRFYLLASKIVFINDNLYLYRRRS
                     GSIMRTEFDLSWARDIVEVFSKKISDCVLAGLDVSVLRIRFVNLLKDYKQTLEYHQLT
                     DTEEYKDICFRLKLFFDAEQRNGKS"
     gene            complement(11405..12601)
                     /locus_tag="ACL29Z_001381"
     CDS             complement(11405..12601)
                     /locus_tag="ACL29Z_001381"
                     /EC_number="2.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001232144.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016757 - glycosyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 8 protein"
                     /protein_id="HGR0069680.1"
                     /translation="MRKSIVLAADNAYLIPLETTIKSVLYHNRDVDFYILNSDIAPEW
                     FKLLGRKMEVVNSTIRSVHIDKELFESYKTGPHINYASYFRFFATEVVESDRVLYLDS
                     DIIVTGELATLFEIDLKGYSIGAVDDVYAYEGRKSGFNTGMLLMDVAKWKEHSIVNSL
                     LELAAEQNQVVHLGDQSILNIYFEDNWLALDKTYNYMVGIDIYHLAQECERLDDNPPT
                     IVHYASHDKPWNTYSISRLRELWWVYRDLDWSEIAFQRSDLNYFERSNQSKKQVMLVT
                     WSADIKHLEYLVQRLPDWHFHLAAPCDCSEELTSLSQYTNVTVYQNVLHSRIDWLLDD
                     SIVYLDINTGGEVFNVVTRAQESGKKIFAFDITRKSMDDGLYDGIFSVERPDDLVDRM
                     KNIEIE"
     gene            complement(12610..13830)
                     /locus_tag="ACL29Z_001382"
     CDS             complement(12610..13830)
                     /locus_tag="ACL29Z_001382"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000938701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016757 - glycosyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HGR0069681.1"
                     /translation="MRNTKRAVVFAGDYAYIRQIETAMKSLCRHNSHLKIYLLNQDIP
                     QEWFSQIRIYLQEMGGDLIDCKLIGSQFQMNWSNKLPHINHMTFARYFIPDFVTEDKV
                     LYLDSDLIVTGDLTDLFELDLGENYLAAARSCFGAGVGFNAGVLLINNKKWGSETIRQ
                     KLIDLTEKEHENVEEGDQSILNMLFKDQYSSLEDQYNFQIGYDYGAAAFKHQFIFDIP
                     LEPLPLILHYISQDKPWNQFSVGRLREVWWEYSLMDWSVILNEWFSKSVKYPSKSQIF
                     KLQCVNLTNSWCVEKIDYLAEQLPEVHFHIVAYTNMANELLALTRFPNVTVYPNSLPM
                     LLEQIVIASDLYLDLNHDRKLEDAYEFVLKYKKPMIAFDNTCSENLSEISYEGIYPSS
                     IPKKMVAAIRSYMR"
     gene            complement(13861..16305)
                     /locus_tag="ACL29Z_001383"
     CDS             complement(13861..16305)
                     /locus_tag="ACL29Z_001383"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866442.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SP_1767 family glycosyltransferase"
                     /protein_id="HGR0069682.1"
                     /translation="MNKTIVLAGDRNYTRQLETTIKSILYHNRDVKIYILNQDIMPDW
                     FRKPRKIARMLGSEIIDVKLPEQTVFQDWEKQDHISSITYARYFIADYIQEDKVLYLD
                     SDLIVNTSLEKLFSICLEEKSLAAVKDTDGITFNTGVLLINNKKWRQEKLKERLIEQS
                     IVTMKEVEEGRFEHFNGDQTIFNQVLQDDWLELDKEFNLQVGHDVTAFYNKWENYFNE
                     LVPPSIIHFVSYRKPWTTLIANRYRDLWWEFHDLEWTKILQHHIGEFELTSSLDKEFS
                     CLTLTNSQDLEGIEELVTALPDVVFHIAAWTDMGDKLKKLAVYNNVRLHPQIVPPVLD
                     KLERSVDLYLDINYSHVVGTILEDMKILEKPILSFDTTEHGNTGQLVFKKDEVSVMVQ
                     AIKDYRRDGRFLSCYEGSDFHCLTFTNSQELQKIDYLVKNFPMVTFHIAAWTVMGPML
                     QKLAKKYKNVKLYPEVKSDQFEELKSQMDVYLDINLHNSTSEVVKEISSLNKPMLAFY
                     TSQNGNHGQHLYSSEHPERLLQAFHALIKGETLGEPEKPIKVIGIDQTLDYVIKNKSS
                     LVRFGDGEVNLMWGLPIPYQNHDLELANQLKHIVGLESDEKLVVCLPDAFDDRFVFTW
                     WATPFWKEHMNVYMDFYKELCKGSWYGSTFISRPYIDYEDKSKAKGQFEKLKSIWENR
                     DILIVEGITSRSGVGNDLFDKVKSVKRIICPSHNAYSVVDNIQEEIMKHAEGRLILCM
                     LGPTAKVLSYNLCQMGYQVLDVGHIDSEYEWMKMGAKTKVKFSHKHTAEHNFDQDIEF
                     IDDETYNSQIVARILN"
     gene            complement(16315..17325)
                     /locus_tag="ACL29Z_001384"
     CDS             complement(16315..17325)
                     /locus_tag="ACL29Z_001384"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000766254.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar transferase"
                     /protein_id="HGR0069683.1"
                     /translation="MKLHLTNLYGMAGDSTVILAQNAVQKIASQLGFREVGIYFYNIA
                     SDSPSEMNKRLDGIMASISIGDILVFQSPTWNGFEFDRLLFDKLKDMQVKIICFIHDV
                     VPLMFDSNYYLMKDYMYMYNLSDVLIVPSERMKTRLMEEGLTTKKILVQGMWDHPHDL
                     SLYTPAFKKELFFAGSLERFPDLQNWSQDTPLRVFSNKGEASSNARNLSIEGWKKDEE
                     LLLELSKGGFGLVWGTHQNDGESNQYYTLNISHKVSTYLTAGIPVIVPSNLSTAKFIV
                     DQGLGFMADSLEEVHAIVDKMNLQEYQEMTNRIKTFSYLLKEGYFTKKLLVDAIYHLG
                     ID"
     gene            complement(17354..18233)
                     /locus_tag="ACL29Z_001385"
                     /pseudo
     CDS             complement(17354..18233)
                     /locus_tag="ACL29Z_001385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000426741.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
     gene            complement(18273..19151)
                     /locus_tag="ACL29Z_001386"
     CDS             complement(18273..19151)
                     /locus_tag="ACL29Z_001386"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000739288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016746 - acyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0120225 - coenzyme A binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acyltransferase"
                     /protein_id="HGR0069684.1"
                     /translation="MKKNHLVGDALILTVSDQIEELDYLLESLPNICFYIAAPVQFSE
                     KIRSLETNYNVRLRTITNEEQLNFLVDTCDFLLDINHFQEVDAIVSKFVQAGKSVFAF
                     DNTVHGNQGQEVFLSSTPDKLVSRVRDYLNEVRVGTNHQEKIIQDGTWNVFKIDDKAH
                     FIVGANVACRNFENFHVSSGKLILNDGVFINNSCSFNCMERIEIGAGTMMGEGVRFYD
                     HDHIYTAEKIEKWQWTTAPIRVGRDCWIGSNVTILKGVTIGDNTIIGAGCLIRNDIPS
                     NSVVYNNGNLFVKRRD"
     gene            complement(19148..21232)
                     /locus_tag="ACL29Z_001387"
                     /pseudo
     CDS             complement(19148..21232)
                     /locus_tag="ACL29Z_001387"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000341103.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0016757 - glycosyltransferase activity
                     [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
     gene            complement(21293..>22810)
                     /locus_tag="ACL29Z_001388"
     CDS             complement(21293..>22810)
                     /locus_tag="ACL29Z_001388"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_078464109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005576 - extracellular region [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HGR0069685.1"
                     /translation="SASASTSASASASTSASASASTSASASASTSASASASASTSASA
                     SASTSASASASTSASESASTSASASASTSASVSASTSASASASTSASASASTSASASA
                     STSASASASTSASVSASTSASASASTSASVSASTSASASASTSASASASTSASASAST
                     SASASASTSASASASTSASESASTSASASASTSASASASTSASASASTSASASASTSA
                     SASASTSASASASTSASASASTSASASASTSASASASTSASASASTSASASASTSASA
                     SASTSASASASTSASASTSASTSASTSASTSASESASTSASTSASTSASASASISASE
                     SASTSASASASTSASASASTSASASASTSASASASTSASASASTSASASASTSASASA
                     STSASVSASTSASESASTSASASASTSASASASTSASASASTSASASASTSVSNSANH
                     SNSQVGNASGSTGKSQKELPNTGTESSIGSVLLGVLAAVTGIGLVAKRRKRDEEE"
BASE COUNT         7173 a         4891 c         3691 g         7055 t
ORIGIN      
        1 aaaagaaaac ttcagaccaa tccacaaaag gtgaatatct gaagttttct tttatttata
       61 agtaatcacc ataaaggtta atagtagaac aaataaagcc aaactcacca ataaagtgag
      121 caccttgacc aaggtgttgc tctgccagta gcttggttta ccaatattac tagtggcatc
      181 catggaaaat agttgatttt gacggggttg tatagttacc aatacaatca aagcaagaga
      241 taggataata gctaaaacaa ttagtatgtc aatcatagat ctacctcaaa attcccagca
      301 aagtaaagag caaaccaatc agaatcatta agcccagtaa aagtgaaaaa gtcttactaa
      361 tcttttcccc tcgggtttct ttttccttct tgatgggttt ttgtttcaac tcttccatgc
      421 ggccttcaac gtctttgtaa aataaatctt cctctgacat gttagcctcc taaaacagtt
      481 tgcatggttt cctgatatct caccaagtca acataatttg catgttggcc ttgtttgcca
      541 agtgcctgac gcatttgatc aacatctgaa agggccaatt taatggtctc aaccaaagca
      601 gcaacttcac tactttcaaa tagatggtct ggagcgatat aaagtctatt gtgcaccgtc
      661 tgattaaagc caagaatcaa gagattgtgc tcaaaggcct gacgcactgc ctgtagcaac
      721 tcattactgt ggtttatatc caagtaaata tccgacagtt gatacagctc ctgaatcttc
      781 tgtggactag cgttctgata aaggaccaca ttaggataac gaagcatatc taagagctta
      841 gaagacatct ctgtcaccgc tgcaatacgg aaagtgacat caggcaaggc tcctgcgatt
      901 gcttctactt gctcaatctg atctgaattg gtcaagatta aggcatctcg tcttaggaaa
      961 ttatcacatt tgaactggta atgataaccc aagtgcacaa actgatcatg gtatttctcg
     1021 tcagttaact ctaaagcgcg ctcataagtc gccttatttg gaatgatgat cttcttagta
     1081 cgcacattat cactttccaa aatcaactgc atattacctg gaatggcatc atagagagat
     1141 tcctgccata ccaagacatc cgagccagat ttatctggat gatggaagga aaccaagaaa
     1201 ggagtcgcta gagtattaaa gataagctga ctggtgtcta tttccaaatc ttgcaaaaag
     1261 aaggtgataa attcaacttt atttgcaaag taacgcatgg actgacctgg caaagtcaat
     1321 aagatatcac ccgtcacatg gttttccaaa ataacttcct tttgatctac gtcccgatag
     1381 gaagtcataa tagcttgccc caaaacatca taagtggttt tagcaaagca agcaccaaag
     1441 cgattatagt ggtcaacctg acgtactcga ccttctaggt ctttccagtc tacctgttta
     1501 accaagcgag cctgcattcc atcagcataa tgaatgacag ccctctcctg cgtcacatct
     1561 tcaatacaag cagactgatt atctcctaaa atttcccaaa aatctgaaac gggaacttga
     1621 ttaaaataga gaggttttcc atcctcgtaa cctagataat aggtaaaagg agaaagcaga
     1681 ccatcaggca gaaaaccatc tgcatcgatg accactccaa gttgagaaag accagtagcg
     1741 actagacttt catgtaaatc tcgactttca tgactataac gatcataaag ttcaatcatg
     1801 gagcacctcc tctactgttt tcttccactt ttctaaaatt tctttggtca agaagccttc
     1861 tgcaatttgg taagaatagg cacgcatagc ttccaaacga ttttcttgat acaattgaca
     1921 aatcttagcg gcataagctt gcttgatttg gtcttctaca tggtcagatg aacttggaat
     1981 caaataacca ttttgcccat cctctataaa ggtctgatta ccataaggca catcaaaacc
     2041 aattagaggt agacctgaac caatagcttc catcaaggtc agaccaaatc cttcgctggt
     2101 agaagccgtt aagtagacct catactggct ataaatctgc gaaagttccg catgcccctt
     2161 gagttggata tagtcctctg cctgatgatt tgcaataatg tctctaagca gagaatcttc
     2221 tccaccacta ccatagatat caaaggttag ttccggtaac tccttatgag cttcaatcac
     2281 agctttcaca agccaatcaa tgtgcttttc tttggcaaga cgtgaagccg taatcaatga
     2341 aaatggtttg cgcccttgac ttgaatctgt caaggaatca atactgccta caggaatggt
     2401 aacaatcttt ggctgatgct gagtatattt ggcaaattgc tcttgtagaa cttcattttg
     2461 tctatcagta gacacgataa agaagtcaac cttatctgca ttggtaaact gatagtcata
     2521 atagttattc caaaggatgt agtcctcatt tgtagcattt tcactataat gctccgcatg
     2581 aacaactacc gctaaatgtg ctgtctgtgc ttcctcaaac acaacctgac caatgcctgt
     2641 ctccctatcg agaatgacca aatcagactt attcaaattc aaagatttca taaaggcacg
     2701 cacaaaagct tgctttccat agaaaatctt atccttgaaa tgataaactt cttccttccc
     2761 ttgattcatc aagatatcat agactggagt cccgtcttca ttataaaaag ttcgttggta
     2821 taagactgca acattgtcct tgggagcaaa atactcgcta caataacgcg tataagaaaa
     2881 gtaatccttc cgaatcaggt ttcccttaaa aacatactcg gcatgttgaa ccaagtcctt
     2941 gttctcatca accaaataac aggttacaaa cttatcttgg tcaaaaaaga atacacgtaa
     3001 aaccttgcca tttttttctc tgtgactttc ttcaccacca aagtaagcca agacatcatc
     3061 cactgtcacg ctagtaggtg caattttgat atctgtgaaa tgattataaa gccagataac
     3121 ctgattatca tcaaaaccaa tattggctgt taagtgctga atattatcgg ctaaaatcat
     3181 atctgtaaag ataaacttag aggacagatt taatttccga aaaacaccag cacgataggc
     3241 ttgagcgtat tcaacaccgc tactagccca accaattcct aaatttatat tgtaaattgt
     3301 catattttct cctcttatgg aaaatgagtc acgatttcac cttttggagt gacctcaacc
     3361 agccccatca ggagattacg caccatatcc gcacggattt gttctttcat agcttcaaag
     3421 cccgcgtagg cttcttgata gtactctacg attggatttt tctgactagc agattgacca
     3481 ccgatagcca tggatagctg ttgtagatag tctacctgct ctacccagtt gtcatcaatg
     3541 gctttaagca gtgaaagtcg taaaaactgt tcatataagt catgttgatt aagtaattct
     3601 ttcttttcag aaagttcttt atcaatcacc tgcttcataa agctacgaac tgcagttttg
     3661 tcagttacat ctatataatc tggaacctct ttaacatgaa aactaatatt ggtcacaata
     3721 aagtgaaaca ataattcacg actagcatag tgatcagccg ctacctcttc tgtatatctc
     3781 tcaatgatat ccacaacaac atcctctaag tcacgagaac catctattag acgatttctc
     3841 tctttataga ctatatcccg ttgtatattc atactttcag catactccag agtctgacga
     3901 cgtgctgaac gtccagcact atcactggca tgctgagcct tttcgactag tttccggtat
     3961 ttacgacctt tcaatacttc cggttgagtc atatcttgaa cctgatagtc tttgtacttt
     4021 ttatgcaccc aagatggacc aaatttcttg ataacatcat cctctaagga tacaaaaaat
     4081 ttactcatac caggatctcc ctgacgacca gaacggccac gaatttgtag gtcgatccgc
     4141 tgactttcca tccgctcagt cccaataaca atcaagcccc caagctctgc gactccttta
     4201 ccaagcttga tatccgtacc acgtcctgcc atagaggtag ccactgtcac agcccccatc
     4261 tgacctgact cggagataat ctgagcctca cgcgccgcat tattagcatt taggacatta
     4321 tgggcaatcc cttcacgaaa caagagagac gaatagagtt gagacatttc aactgagcct
     4381 acaaaaacga gtaaaggatt tcccttagca tggtattcct tgatgtactc caaggatgca
     4441 tacacttttt caggtaaagt gatatataga ttatctggat agtcaatccg ttgtctcgga
     4501 cgattggttg gaatgcgtac tacagacata ttgtaagttt caataaactc tttttccgcg
     4561 accttacctg tccctgtcat accagatatc ttattaaaca tcttaaaaag actctgatag
     4621 gtgatcgagg ccatagcccg cgtctcagga gataatttga catgttcctt ggcttcaata
     4681 gcctgatgga gacctccttg aagtttagtc atttccatta gacgccctgt tcccttatca
     4741 accagtacca tctcatttcc acgaatgata tagtccttat ctttagtaaa gagcttatga
     4801 gctcgaatcg cataaaccaa atgacgagca aaagacgcat gctcttcctt gtataaatta
     4861 tcaatcccta ggaaattctc agcagacttg gcccccttag tagtgagcca aacctcctct
     4921 ttctcctctt taaagatata atcctctcct tcgaccaagg ttgttacaag tgtatcaatg
     4981 atcgcatagt aattagactg aacacgagga gaacccgcaa taatcagagg agtttgtgca
     5041 ctatcaagca agatatcatc aatttcatca ataataacat agttaaacgg tcgtaaaaac
     5101 ttaccttctt cattcgaggc taggttatca tttagataat caaaacctaa actactattg
     5161 gttgtgtaga tgatatccga agcatagata agcttctttt cttcagcttt catttccttc
     5221 tttggatctt ccgtaaatgg tacaccaatg gtcaatccta gaaaacgata aacttggccc
     5281 atttcctcgg catcacgctt tgataaatac tcattaggag tcacaaccat cactccttct
     5341 cctgaaaaag cgttcaaata gacaggcatg gtagctgtca aggtcttacc ttcccccgta
     5401 ttcatctcag caacatttcc atagtgcatg acaatagctc ccatgacttg aacatcatag
     5461 gggaacatcc ctaaaatccg cttatctgct tcacgcacca cagcaaaagc ttcaaccaaa
     5521 atatcgtcta gactttctcc ctcggaaaga cgctgacgaa actctactgt tttagctact
     5581 aattcttgat ccgaaagaga ggacatcttg cctttcaggg cattaatctg ctttaaaatc
     5641 tttttcactt tcctaagctg gaaatcttga cctaaacgtc taaacacttc tgatctcctt
     5701 gatagaaaaa tgataaaaag ttaaggactc aaatccagca cttaaaagag aaacttgata
     5761 agtataacta tcttctggat aagtaaatat gaaatctttc gctttttcta cctttttttc
     5821 taaaatatca ccatagcggt caaaaaaagt tatcttggta taaactccat tttcaggctg
     5881 acaatcaaaa accagtgata gttgatactc ctgctttctt tttaataagg gaagctgagg
     5941 ttgggttcgt gcagcctggt aattgacact agaaaaccaa gtctttagaa tctcaccaga
     6001 tggcaataga ggattataca gacgaacact tttgtcaagg taataagata cagttgttcc
     6061 atacatataa gtcccaccaa cttctcccca ataaatagac tgtctctgtg taataatcat
     6121 cttttctccc ttccaaaacc agtctctaag accattctat aaaagtgcaa aaaccaagaa
     6181 atattggtat ctgtatcatc attgtgtcgt ccagcagttc ctttagataa aatcttcgca
     6241 cctgtattac acagataaga cactaattgt tcataggctt gtggatccat ttcttcatct
     6301 ttcatatagg ataaaccaaa ggttgtcttt gaaaaatttg cttgtttaaa aattttccaa
     6361 aaacgctgat ccaactccgt catatcttga gaacttgtcc cacctgtatg atgaattaaa
     6421 caatcaaaag ctaagttaga gacacccggt gcgtccaaac gtccacgact agctatagtt
     6481 cctaaattag ccaagggctt accaactatg atggcatggg gttcaaaaga agcaccataa
     6541 tagagagccg gaaacgttcc catagaaaga cctgataaaa tcaaatcctt atgatcaaag
     6601 cctaaataat caagatagtg agtgatcgta tcctttactt ttccctctag ctcatccgtt
     6661 ccgagataaa aagctccccc ctctaaacgt ggatcagaaa ataaaatgaa gggacatcca
     6721 agagttttca tcataaagta accctcgaat ccttctgcag gtcgataacc tgcaaaatag
     6781 acagtcaaag gcggtttaaa atcacctgga tggaagaaat agtttatttc atcacgcttg
     6841 gaatcatgta ggatatttcc accaagtaca aacttaccaa attgttttcg actccatcgt
     6901 tggtgaagat tacctagttt gatagttcca cgacctcttg cttcaacaga tatcgagaga
     6961 aagtagtctc cgtctcgact atccataaaa agtgcttgct ccaagtcttt ttcagatact
     7021 attacttctt caaagaaatc atcaacagac ccactccaca ttttacggat tactaaacga
     7081 aagtcacaat tgccttcctt ctcatattca agccacaact caatagggag tgttttttgc
     7141 accataatat tataagccca ataggcaagc tgagcaaaat cttgcccaaa ctcaccttcc
     7201 aaactgacat aatccaatcc ttgataagaa atagctcctg taaaatttgg attgacttgt
     7261 atcgtcggag gaaagagttt atcaccatac ccaccgccaa aaagagattt acttaaatca
     7321 ttgattagtt gttggggact taaaaaatca attgcttgtg cacatcgttt ttttagaaaa
     7381 tccacaacct ctctatcatt tatttgtaga ttctggttat agaacaaagt ataaggttca
     7441 aaatatttta cataggaaaa taagtctctg gaatactgac catcttctat taaaactgca
     7501 tgaaaacggt taatatcctc tttttcgatt atttcacgaa gggtttttga tgagtttggg
     7561 taaaaataat accaactcat attttcaggt atgtcatagt gattttccca attggcaagt
     7621 cctatctgta aaatattaag ttcctttgac atttttaacc tcctctatcc atttctctaa
     7681 ttttccaaga aattgttgtc ctgtgtgctc cttaatctta tcaattgaat atatcaagga
     7741 ctcattccac tccttcaacc tatctgtgta ataatgtgca gccttagaaa attctgtcac
     7801 atctgtcagc aaataaccat tttttaaatg ttccacatag acggtttcaa ctaggttgat
     7861 ttgaggaatt cctgcactaa tcccagcaat ctgtgtgtag agatgaggat gtctatttaa
     7921 atccacaatc aaacggacaa attctagtgt ttttatcaaa tctaactcat cattcaagtt
     7981 aacaaactgt aagcgtaagt cctggtgttg attttcttcc aggggatttt ctgcatcacc
     8041 ataatcaatc gcctttccca gattttcgga ttgaatgttt tcttggatga aagactcaac
     8101 aatcccttca acctcattca tttgctcctg actagcagca aaggctccaa aaatcacctc
     8161 agtatcctta ttttcagcga caaaggacaa gacttgaagc agagcttgat tatcaatccc
     8221 ctgctcaaaa tccagttgaa aataaatgat ggattctttc ttagtttggc ttcgtcccaa
     8281 tcgtaatcgg gtgtcaaaag atgataaatg ataacattga tgcattcgtt caggatacaa
     8341 ctcctgcaac aatcgtaaac tatcctctct atccaccaaa atcaaatccg atttttcaaa
     8401 agttacatct aaatccctaa aggtatcttg aggattacgt ccaatgaaca gactcaacag
     8461 tttaggatta gtactaggta aacgatctag taccaactgg tcatgatgag aatgagaagg
     8521 aagcataaaa atatcctgat ccttcacata cgtttgcaga taattctcaa aaaattctgc
     8581 caccagatct cccatatttt gataggtaag cattttaaag cgataaccca aaattggatt
     8641 gacttctacc tgtcctcctt cttttaaacg ctctctaaat tgccaaactc ccttaggatt
     8701 caaatattct tgataggctg cttgcccatc ttcaaaaaaa ataatactcg atataaaccc
     8761 tcgatcatcc atgatatggt gcatatgtat ttgaacattt ggttcaaaat actgtatatc
     8821 actgatgaag ccttcaactc catgttcaac cttagcaaat ttcttcccat ttttttgaac
     8881 gataatcgta aagggactat aaataaattc acagtcatca tcccactcaa tatctctaat
     8941 gcttaaaact tgggtatgga gattatgaaa atcttgcata acatcaaaaa cggaataagt
     9001 atccgtttct aacacaccat gtctatataa aaaataacgt agatgaggct ggtaagctaa
     9061 tactaataga cgagaatcta tatcttgctc ttgaaagagc cggatctggt gaaaggtatc
     9121 atcaaactct agacgaaaat gagaaaaata ccatggagtg atatctgcat gccatgttct
     9181 ttctgaccca taccaagctg gaataaaata atacataaaa gtctcctaaa tcaaaggttt
     9241 ataggtctca tttagcctta aagccttgac ctcgtctcta atcgtaaaaa tcatgcctcc
     9301 aaacatcata aacaaacctg gaatcattgc caatcgtaat aacttttcat caaacaaaac
     9361 aaaaagcatg ggaccacctg ccataaccac attaaagaga ccacctatga ctgagaaacg
     9421 aaggaccaat cgattaataa atcgactagt atccgcacct ggataaatac cataaatgta
     9481 ttctccagat tttttcatac ggtctgcaat ctcttctcca ttcatcgtaa caaaagcaaa
     9541 aatgatacta aataaaaata agaccgaaat ataaacatag acccacaaag gctttccaat
     9601 cataaattcc tttgataaag ccgctaaccc tgaatgatta gggaaaataa atcccaacaa
     9661 gatgaacaaa taagctggta cactaagaaa actcatcaca tacatataag gcatcccacc
     9721 tgcaggattc aacatgattt cgagataaaa atagcgttta aatcgattgt gtaagccaat
     9781 tttattaaca ggaaccaaat agcgagctcg atacataagg gcaagtaaat aagaaaagac
     9841 aagggttaat aaagcaagta acacaataat ccctgttgga atgtgtactg tctgaaatgt
     9901 ttccaaaaca tcctgaggaa tatttaaaac catactggat aggagaatga ctatagaacc
     9961 tccaatcccc atactcgcat ttaaatctga caaccaaaca agaaaaaatg ttcctgctat
    10021 cagcaatatt gtattcatta gaacaaccaa tattgcagaa taggaggatt gtactggcag
    10081 tctcaagcta actgccaatg attgaatgac agctatcatc aaggtcaggt acattttacg
    10141 gcgatcttgt atttctatag acgtagatgt taaacccaac cgtttagaaa aagaaaacat
    10201 ctgccataaa atcatagctg acatccaagg ggacaatcca acagaaaaaa ttgacaaact
    10261 tcttagattt ccacctgtta gggcggctga gaaggctaga taggctgttg aacctcctaa
    10321 aaaatcttta gtatttaggt caacaaaagg gagagtaata cgacttccca atacatagat
    10381 aaacagtaga aataaggtaa atagtccttt ttttactgct attgacgaat aaatcttagt
    10441 cataaaacac tcccctcacc ttcattgttt gtgatatggt aaataacaat tcttttattt
    10501 caacttttac catttctttg ttctgcatca aaaaacaact ttaatctgaa acaaatatct
    10561 ttatattcct cagtatctgt taattgatgg tattctaaag tttgcttata atcttttaaa
    10621 agattgacaa atcgaatacg cagaacggag acatccaaac cagccaagac acaatccgat
    10681 attttcttag aaaacacttc aacaatatct cttgcccagg aaagatcaaa ttccgttctc
    10741 atgatgcttc ctgaacgtct tctatacaga tagagattat cgtttataaa gacgatttta
    10801 gaggctaaaa gataaaagcg atgcatagtt gcttcatcat caaagcggcg accatttgaa
    10861 aagtgaactt cattgaataa ttctttttta atcaacttaa atgtcggcaa tataaaggcc
    10921 gagctattga atttccaatc tcctgcttga cggttcataa tttcttgtat agctaattct
    10981 tcgacgcaaa aatcttgccc tgttacataa aaataaaaat tcccgtcact ttcgtcataa
    11041 ttatagtaat tccctataac aacatctgca tccttttctt ggacttgctg ataaagagtt
    11101 tcaatcatat tttcttttac gatatcatct gaatcaacaa tcgtaatgta ctctccctta
    11161 gctacactaa tccccatatt tttagcttgt gctgcccccc ccttattttc ttgatgcaat
    11221 actcgcacac gattatcttg catcataaaa gcatcacaaa tttccccaga attatccgta
    11281 gaaccgtcat caactaaaat aatttctata ttttgatagg tttgcttcag aatatgctcg
    11341 acacactcca ctaaatattt tcccgtattg tatatcggta ccacaacact aattaattca
    11401 ctcattactc tatctctata ttcttcattc tatccactaa atcatctggt ctctccacag
    11461 aaaaaatacc gtcatagagt ccatcatcca tacttttacg tgtgatatca aaagcgaaga
    11521 ttttcttgcc actttcttgt gcccttgtaa ctacattaaa aacctctcca cctgtattaa
    11581 tatctaaata aactatagaa tcgtccaata gccaatcaat tctactatgt aatacatttt
    11641 gatatactgt tacattcgta tactgtgata gagaggtcag ctcctcagaa caatcacacg
    11701 gtgcagccaa atgaaaatgc caatcaggta accgttgtac taaatactct aaatgtttta
    11761 tatctgcact ccatgtcaca agcatcactt gttttttaga ctgattgctt ctttcaaaat
    11821 aatttaaatc ggaacgttga aaagcaatct ctgaccaatc caaatctcta taaacccacc
    11881 ataattcacg tagtctagat atactatatg tattccaagg tttatcatga ctagcatagt
    11941 gaacaattgt aggtggattg tcatctagac gttcacattc ttgagcaagg tgataaatat
    12001 caatacccac catataatta tatgttttat ctaaggctag ccaattatcc tcaaaataaa
    12061 tatttaaaat actctgatcc ccaagatgaa caacttgatt ctgctcggcc gctaattcca
    12121 ataaactatt gacaatagaa tgttctttcc actttgcaac atccattagt aacataccag
    12181 tattaaatcc agattttcgt ccttcatagg catagacatc atcaacagca ccaattgaat
    12241 atcctttgag atctatctca aacaaagtag ctagttcccc agttacaatg atatcggaat
    12301 ccagatacaa taccctatca gattcaacca cttctgtcgc aaaaaatcta aagtaagaag
    12361 cataatttat atgaggtcct gttttatagc tttcaaaaag ttctttatca atgtgtacac
    12421 tgcgaattgt agaattcaca acttccattt ttctccccaa taatttaaac cattcaggag
    12481 ctatatcact gttgagaata taaaaatcaa catctctatt gtgatacaat acagacttta
    12541 tagtcgtctc taaaggaata agataggcat tatctgccgc taatactatt gattttctca
    12601 tactgttctc tacctcatgt aagatctgat tgctgcaacc atttttttcg gaatggagct
    12661 tggatagata ccttcatatg aaatctcaga aagattttca gagcaagtat tgtcgaaagc
    12721 tatcattggt tttttgtact taagcacaaa ctcatatgca tcttctaatt ttcgatcatg
    12781 attcaaatcc aaatacaaat ctgaagctat tactatttgt tccaataaca ttggtaagga
    12841 atttggatat acggtaacat taggaaaacg cgttaaagct agtagttcat ttgccatatt
    12901 tgtataagca acaatatgaa aatgaacttc tggcaattgc tctgccaaat aatcgatttt
    12961 ctcgacacac caagaattcg ttaaattaac acattgcaac ttaaatattt gtgatttact
    13021 aggatacttc acactctttg aaaaccattc atttaaaata acagaccaat ccatcaaaga
    13081 gtattcccac caaacttctc ttagacgtcc aacagaaaat tgattccaag gcttatcctg
    13141 agaaatatag tgtaaaatta gtggcagtgg ttcgagcgga atatcaaaaa tgaattgatg
    13201 tttaaaggct gccgccccat aatcatatcc tatttgaaaa ttatattgat cttcaaggga
    13261 actatattga tctttaaaca acatattcaa aattgactgg tctccttctt ccacattctc
    13321 atgttctttt tctgttaagt caatcaattt ttgtcgaata gtttcagatc cccatttttt
    13381 gttgttaatc aagagaacac cagcattgaa gccgactcct gctccaaagc aagaacgagc
    13441 tgctgccaaa taattttcac ctaagtctaa ttcaaacaaa tcggtcaaat caccagtcac
    13501 aatcaaatca ctatctagat agagaacttt atcttctgtt acaaaatctg gaataaaata
    13561 gcgtgcaaat gtcatatgat tgatatgagg taatttatta gaccaattca tttgaaactg
    13621 tgagccaatt aacttgcagt caatcaagtc gccccccatc tcttgtaaat atattcttat
    13681 ttgactaaac cattcctgag gaatgtcctg atttagcaga taaattttca aatgactatt
    13741 gtgtctacag agtgacttca tcgccgtttc gatttgtcga atataagcgt aatcacctgc
    13801 aaatactaca gcgcgtttgg tatttctcat tttaaatcct tatcatttat tttaaatagt
    13861 ctagtttaat attcgtgcaa caatctgact gttataggtt tcatcatcaa taaattcaat
    13921 atcttggtcg aaattatgtt ctgcagtatg tttatgagaa aatttaacct tagttttagc
    13981 tcccattttc atccattcat actctgagtc aatatggcct acatccaaaa cttgatagcc
    14041 catctggcat agattataac tcagaacttt tgctgtagga cccagcatac ataaaatcag
    14101 tcttccttca gcatgtttca taatttcctc ttgaatgtta tcgacaacgg aataagcatt
    14161 atgagatgga caaataatcc ttttcacaga tttgacctta tcaaataaat catttccaac
    14221 cccagagcga gatgtaatcc cctctacaat cagaatatcc ctattctccc aaatactctt
    14281 tagcttttca aattgtcctt ttgccttact cttatcttca taatcaatgt atggacgcga
    14341 gataaaggta gagccatacc atgaaccctt acacaactct ttataaaaat ccatataaac
    14401 attcatatgt tctttccaga atggtgtagc ccaccaagta aagacaaaac gatcgtcaaa
    14461 agcatcaggt aaacaaacca ctaatttctc gtcactctca agacccacaa tatgttttaa
    14521 ttggttagct aactctagat catgattttg ataaggtata ggcaaacccc acatcaaatt
    14581 gacttctccg tctccaaaac gaactaatga ggacttattt ttgataacat aatccagagt
    14641 ctgatcaatt ccgataacct tgattggctt ctctggttct cccaaagtct ctccttttat
    14701 caatgcatga aatgcttgaa gaagcctttc tggatgctca cttgaatata aatgttgacc
    14761 atgatttcca ttttgtgaag tataaaatgc cagcattggt ttattcaatg atgatatctc
    14821 cttgacaacc tcactagtag aattgtgtag gttaatatcc aaataaacat ccatttgaga
    14881 tttgagttct tcaaattgat cgcttttcac ttcaggatat agcttaacat ttttatattt
    14941 ttttgctagt ttttgtaaca ttggtcccat aactgtccaa gctgcgatat ggaatgttac
    15001 cataggaaaa ttcttaacaa gataatctat tttttgcaat tcttgagaat ttgtaaatgt
    15061 taggcaatgg aaatcactac cttcataaca acttaggaat cttccatctc ttctgtaatc
    15121 tttaatcgct tgaaccatga ctgaaacttc atcttttttg aatactagtt ggccagtatt
    15181 cccatgttca gtcgtatcaa atgatagaat tggcttttct aagatcttca tatcctctaa
    15241 aatagtacct accacatgac tgtagttaat gtccagatat aaatctacac ttctctccag
    15301 cttatctaat acaggaggaa caatctgtgg atgcaatctc acattattat atacagctaa
    15361 tttttttaat ttatctccca tatccgtcca agcagcaata tgaaatacca catctggtaa
    15421 agctgtgact aactcttcta ttccttctaa atcttgggaa tttgtcaaag ttaaacaaga
    15481 aaattcctta tctaaagacg atgtcagttc aaactcccct atatgatgtt gtaaaatttt
    15541 agtccattcc aaatcatgaa attcccacca taaatcacga taacgattgg ctatcaaggt
    15601 ggtccagggt tttctgtaag acacaaaatg aataatacta ggaggtacta actcattaaa
    15661 ataattttcc catttattat aaaaagcagt tacatcatga cccacttgaa ggttaaattc
    15721 tttatccagc tctaaccaat catcttgtaa gacctgatta aaaatcgttt gatcaccatt
    15781 aaaatgctcg aaacggcctt cttcaacttc cttcattgta acaatgctct gttcaattag
    15841 tcgttctttt aatttctctt gacgccattt tttattgttg attaatagaa cacctgtatt
    15901 aaatgtaatt ccatctgtat ctttaactgc tgcgagtgat ttttcttcta aacaaatact
    15961 aaataatttc tctaaagaag tatttacaat caaatcactg tctaaatata aaaccttatc
    16021 ttcttggata taatctgcaa taaaatatct agcataggta atgctactaa tgtggtcttg
    16081 cttttcccaa tcttgaaaca cagtttgttc aggtagcttc acatcgataa tctcactacc
    16141 taacatgcga gctatttttc gtggctttcg aaaccaatct ggcatgatat cttgatttaa
    16201 aatataaatc ttaacatctc gattgtggta tagaatagat tttatggttg tttctaactg
    16261 cctggtgtaa ttacgatcac cagctaatac aattgttttg ttcatttcac tcccttaatc
    16321 aattcccaag tgataaatcg catctaccaa tagcttttta gtgaaatagc cctcttttag
    16381 cagataacta aaggtcttta tcctattcgt catttcttga tattcttgta gattcatttt
    16441 atcaactatc gcatgtactt cctcaaggct atccgccata aaacctaagc cctgatctac
    16501 tataaattta gcagttgata agttgctcgg tacaatgact gggatgcccg ctgtcagata
    16561 ggtactaacc ttgtgagata tatttaaagt atagtattga ttgctttctc cgtcattttg
    16621 atgcgttccc cagacaagac caaagccacc ttttgataat tctagcaaca gttcctcatc
    16681 ttttttccat ccttcaatgc taagatttct agcattggaa ctagcttctc ctttatttga
    16741 aaacaccctc aaaggcgtat cttgagacca attttgtaag tctggaaaac gctctaaact
    16801 tccagcaaaa aaaagttctt ttttaaaagc aggggtgtat aaggataaat catgaggatg
    16861 atcccacatc ccttgaacaa gaatcttctt agtcgtcaat ccttcttcca tcaggcgtgt
    16921 tttcattctc tctgacggca ctatcaaaac atctgataga ttatacatgt acatataatc
    16981 tttcatgaga taatagttac tatcaaacat gaggggaaca acatcatgga taaagcaaat
    17041 aattttcacc tgcatatcct ttagcttatc aaacaagaga cgatcaaatt caaagccatt
    17101 ccaggttgga gactgaaaga ctaaaatatc cccaatagag atactggcca taataccatc
    17161 cagacgctta ttcatttcag aaggactatc tgaagcaatg ttgtaaaaat aaataccaac
    17221 ctctctaaat cccagttgac tagctatctt ttgaacagca ttttgagcta agataaccgt
    17281 actatcacca gccatgccgt ataaatttgt taaatgtagt ttcatattac gctatctcat
    17341 tttttattac tatctacgga agtaaagaca atttttccat cattcttctg taaatctctg
    17401 tgaactgcat attttgttct tctaattttg ctatcactct ttgtaatcta tttttataaa
    17461 tcaaaatatg attggtcaag tcatagtctg aacttgctaa aatagctatc ttttcttccc
    17521 tagccccaat ttcatcatac atacgctttt cactccatgt attcgataaa gtatcagata
    17581 aaccaacacg gtaccagtaa acacaacgat tcaaatagac tatcctcgaa gctcttagaa
    17641 gtaccttcca tgtccagtaa gtatcctctg caatttttcc tataggaaat ggtaaatctt
    17701 gtagtaactc tctcttgaat aacttcaaga cagctacagt ccagttccca tttctgactt
    17761 cttcgacacc ttccctatcc ataattgctt taccttctat cacttctaga gaatcatctg
    17821 gatccgtaac ataagtcata tacacatagc gtgtttcatc ataagaatta taacgcccga
    17881 tactaatatc tgcgttttcc tttttcaaag caccatataa tcggtctaaa gcatcatgtt
    17941 ccaaccaatc atcagagtct acaaaagtaa tgtacgcccc ccccccccga acattcaata
    18001 cctaggttac gagctgatga aagaccgccg tttgctttct caaaatattt gaaacgagaa
    18061 tctttctcta caaattcttc acatattttg gatgaatgat ctggagagcc atcattgatt
    18121 aataaacact caaaattttg atacgtctga ttctgaatgc tatccaaaca cattcgcaaa
    18181 taattctcaa cattgtagat tggaactaca atactaatta gttcattttc catatactaa
    18241 ctttcctaga cttgatttat tctatttccc tcttaatctc ttctctttac aaaaagattt
    18301 ccattattat aaactacact gtttgatgga atatcattgc gtatgagaca acctgctcca
    18361 ataatggtat tatccccaat agtcactcct tttaaaatcg tgacattact tcctatccag
    18421 cagtctctgc caactctaat cggcgctgta gtccactgcc acttttcaat cttttcagcg
    18481 gtataaatat ggtcgtgatc ataaaaacga acaccctctc ccatcatggt accagctccg
    18541 atttcaattc tttccataca gttaaaacta caagagttgt tgataaaaac accatcattc
    18601 aggattaact taccagaaga gacatgaaaa ttttcaaaat ttctacaggc gacattggct
    18661 cctacaatga agtgagcctt atcatcgatt ttaaagacat tccaagtccc atcttgaatg
    18721 attttctctt gatgattggt gcctactctg acttcattca gatagtctct cactctagaa
    18781 accaatttgt ctggtgtact tgatagaaaa acttcctgcc cctgatttcc atggactgta
    18841 ttgtcaaatg caaagacaga ttttccagcc tgtacaaact tggagacaat agcatctact
    18901 tcttgaaagt gattgatatc tagtaaaaag tcacaggtat cgactaaaaa gtttagctgt
    18961 tcttcatttg taatcgttcg gagacggaca ttatagttcg tttctaagct acggattttc
    19021 tcggaaaatt gaacaggtgc tgcaatataa aaacagatat ttggcaagga ttcaaggaga
    19081 taatccaact cttcaatctg atcactaaca gtcaaaatca gagcatctcc tactaaatga
    19141 tttttcttca tttgcttatt tctcttaatt tttcaatcat tgcttgaact tggtcaacag
    19201 catatgcctc ctgacctact tcataggttt tagtattttc aaaggataag ataggcttgc
    19261 caagattagc aaattgatcg agaatttctt ctgtcttttc gccatgatta atatctaaaa
    19321 gtacttgact ggtttctacc aattcattat cgacatctac caaatagtga attccgttaa
    19381 atatagtcac gtttggataa attgtcatct gagccaatcg atcactaact attactctag
    19441 ctgctatctt aaactgaata tcaggcaagg attgaaccaa tgtctcaatt tgttcaatat
    19501 ggtctgaggc agtatagatt agacaagtga aaggttcctt tattggatag atgtgagatc
    19561 tttgtaatgg atgtaaatga tggttttgtc ccaattctgt ccattcaagc ccatgatagt
    19621 accaccaaac ttcacgatag gtttgggccg ccaaatcttt ccacggtttc cgatgagaaa
    19681 gatagtgaat aatagcagga taatcctgac cctcaggcaa ttgataatca gcgaactgtt
    19741 tatgaatgac aatatgatta taatcaaagt ccaattccaa ccatttatgt tcaaaaagca
    19801 tattcaaaat actttgatca gcctgttcca ccttattatg ccattcatta gtcaaatcaa
    19861 ttaatttttg ggtcatattc tcttttttcc aaaaagcatt gtttaccaag agaacaccgg
    19921 cattaaagat ttcttgacca aaataagctc tgcccccaaa atctctaaca gcagccaaag
    19981 gataatcttg taagtctgta gcaaacaaat catccagatt tttcgttaca agtaaatcac
    20041 agtccaaata gagggcctta tcttcttgca cgaaatcagc tatgaaatag cgtaaaaaaa
    20101 ctgtgtaact aatatccgtt ttataacatg aaatttgctc agaagttacc cgacaattaa
    20161 taatttctga gtcaaacttc tctaagcgct tatttaattg cttaatccat tcatttggaa
    20221 aatcgctatg aatcaaataa aaacgaagcg agcgattgtg gtaacagata gacctgattg
    20281 tcgttaaaac ttggtctaca taggcataat ttgccgctag gacaatggct ttcttttcac
    20341 ttgattcttg taccgttaac tgatttaaaa gtcttttttt catttcaaac tctttataca
    20401 ttgctgtgtc agataaacca ctagcttaac cgttggcgag actgacttcc aacatctgac
    20461 gataaactgc caagtgtttc tctagaggat atcccatatt agctagtagc gtaatacgtt
    20521 cagacatagc atcaactaag gcgtgcatcc acttttctgt ccaaactctt gataaactac
    20581 cttttctaat ccgataagca taaagacctt tatttaaata aattaccttt tccgataata
    20641 aatatacctt ttgattgagg taaccatctt ctcctaattt acccatgtca aagcgcaact
    20701 gctcaaacaa tcttgcctta tagagtttac cacaagcaga tatcaaagca aaactcttca
    20761 tttcttgagt ttcatacaag ttctcaaaga tggaaacatt gtcatatacc ttatcataat
    20821 aggagtctcc tgatatatga aagtagaaca ttccttcact ttcgttgaaa gaatagtaat
    20881 tcccaactgc aatatcagct tgatattctg ttattttttt atatagggtt tctacataat
    20941 ctaactcaat ccaatcatct gaatccacaa aggtcacata atttccggac atattattca
    21001 gaccggtgtt tcgtgcggca gaaataccag cattttcttg ttctatatag agaattcggt
    21061 gatccatttc tgaaaattct ttacaaattt cacctgaagc atccgtagaa ccatcattaa
    21121 cgacaacaat ctcaatattt ttatatgttt gagaaatgat actatctaga catttcctca
    21181 gatagttttc tacattgtat actggtacaa tgaccgtaat tttatcatcc actagcaatt
    21241 ttctccttga tttatgtgcg cgagttagtt tagcctaact ttacaggttg tcttactctt
    21301 cttcatcacg tttacggcgt ttcgcaacca atccaatacc tgtaacagct gctagaactc
    21361 caagtaacac agatccaatt gacgactcag tacctgtatt aggcaattct ttttgggatt
    21421 tacctgtcga tccagaagca tttccaactt gtgagttcga atggtttgct gaatttgaaa
    21481 ctgatgtact tgctgaagct gacgcactgg ttgatgctga agccgaagca ctcgttgatg
    21541 cggatgctga cgcactggtg cttgctgaag ccgatgcact tgttgatgcg gattcagagg
    21601 cactggttga cgctgagact gaagcactgg ttgatgctga ggctgaggcg ctagtacttg
    21661 ctgaagccga cgcactggtt gacgctgaag ctgaggcact cgttgaggct gaagccgaag
    21721 cactcgttga tgcggaagcc gaagcactgg ttgatgctga agccgatgcg cttgtcgatg
    21781 cggaagctga tgcacttgtt gatgccgatt cagacgctga gatacttgct gaggctgagg
    21841 cgcttgtact tgctgaagtc gacgcactgg ttgaggccga ttcagatgct gacgtacttg
    21901 cacttgttga cgccgatgtg cttgcacttg tcgatgctga cgcactcgtt gatgctgaag
    21961 ccgaggcgct ggttgatgcg gatgctgacg cactggtgct tgctgaggct gacgcacttg
    22021 ttgatgctga agctgaggca ctggttgatg ctgaagctga cgcactcgtt gatgctgagg
    22081 ctgacgcact tgttgatgct gaagccgaag cacttgtcga cgctgaagcc gaagcactgg
    22141 tgcttgctga agccgaagca ctcgttgacg ctgaagctga ggcacttgtt gatgctgaag
    22201 ctgacgcact tgtcgacgct gaagctgaag cgcttgtcga tgctgaggct gaagcactgg
    22261 ttgatgccga ttcagaggca cttgttgacg ctgaggccga ggcgcttgtc gatgctgagg
    22321 ccgatgcact ggttgatgcg gatgctgacg cactggtact tgctgaagcc gaagcactgg
    22381 tacttgctga agccgacgca ctggtacttg ctgagactga agcacttgtg cttgctgaag
    22441 ccgacgcact ggtacttgct gagactgaag cacttgtgct tgctgaagct gaggcgcttg
    22501 tgcttgctga agccgacgca ctggttgatg ctgaagctga cgcacttgtt gatgctgagg
    22561 ctgaggcgct tgtgcttgct gagactgaag cactcgttga cgctgaggcc gaagcactgg
    22621 ttgaggccga ttcagatgct gatgtgcttg ctgaagccga cgcactggtt gaggcggaag
    22681 ctgacgctga ggtacttgcg cttgctgagg ccgacgcact cgttgacgct gaagccgatg
    22741 cacttgttga cgctgaggct gaggcgctag tacttgctga agctgatgca ctagtacttg
    22801 ctgaagcgga
//
LOCUS       DBEJAU010000034        22716 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC323 isolate 683620
            SAMN38261939-rid24807223.denovo.034, whole genome shotgun sequence.
ACCESSION   DBEJAU010000034 DBEJAU010000000
VERSION     DBEJAU010000034.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261939
            Sequence Read Archive: SRR26833919
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 22716)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 22716)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576303.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576303.1
            Genome Coverage       :: 154x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/19/2025 01:05:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,121
            CDSs (total)                      :: 2,078
            Genes (coding)                    :: 1,943
            CDSs (with protein)               :: 1,943
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 36
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 72 of 135
            Pseudo Genes (incomplete)         :: 63 of 135
            Pseudo Genes (internal stop)      :: 51 of 135
            Pseudo Genes (multiple problems)  :: 46 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..22716
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261939-rid24807223.denovo.034"
                     /strain="GPSC323"
                     /isolate="683620"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            275..526
                     /locus_tag="ACL29Z_001389"
     CDS             275..526
                     /locus_tag="ACL29Z_001389"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000657761.1"
                     /note="The YSIRK form of extended signal peptide directs
                     nascent proteins to the cross-wall site, while signal
                     peptides lacking YSIRK direct proteins instead to the cell
                     pole. A large fraction of YSIRK proteins are surface
                     proteins anchored by sortase-mediated processing of a
                     C-terminal LPXTG motif; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YSIRK-type signal peptide-containing protein"
                     /protein_id="HGR0069686.1"
                     /translation="MKEFQFERKQRFSLRKYAIGACSVLLGTSLFFAGMGAQPVQDTE
                     TSSALISSHYLDEQDLSEKLKSELQWFELENKLLNLWEH"
     gene            514..805
                     /locus_tag="ACL29Z_001390"
                     /pseudo
     CDS             514..805
                     /locus_tag="ACL29Z_001390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000501069.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_component: GO:0005576 - extracellular region [Evidence
                     IEA];
                     GO_function: GO:0004222 - metalloendopeptidase activity
                     [Evidence IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ZmpA/ZmpB/ZmpC family metallo-endopeptidase"
     gene            complement(1032..1115)
                     /locus_tag="ACL29Z_001391"
                     /pseudo
     CDS             complement(1032..1115)
                     /locus_tag="ACL29Z_001391"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611514.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(1210..2541)
                     /locus_tag="ACL29Z_001392"
     CDS             complement(1210..2541)
                     /locus_tag="ACL29Z_001392"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000686986.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dipeptidase"
                     /protein_id="HGR0069687.1"
                     /translation="MKIDITNQVKDEFLISLKTLISYPSVLNEGENGTPFGQAIQDVL
                     EKTLEICRDIGFTTYLDPKGYYGYAEIGQGAELLAILCHLDVVPSGDEADWQTPPFEA
                     TIKDGWVFGRGVQDDKGPSLAALYAVKSLLDQGIQFKKRVRFIFGTDEETLWRCMARY
                     NTIEEQASMGFAPDSSFPLTYAEKGLLQVKLYGSGSDQLELEVGGAFNVVPDKANYQG
                     PLYEQVCNGLKEAGYDYQSTEQTVTVLGVPKHAKDASQGINAVIRLATILAPLQEHPA
                     LSFLATQAGQDGTGRQIFGDIADEPSGHLSFNVAGLMINHERSEIRIDIRTPVLADKE
                     ELVELLTRCAQNYQLRYEEFDYLAPLYVAKDSKLVSTLMQIYQEKTGDNSPAISSGGA
                     TFARTMPNCVAFGALFPGAKQTEHQANECAVLEDLYRAMDIYAEAVYRLAT"
     gene            complement(2563..4074)
                     /locus_tag="ACL29Z_001393"
     CDS             complement(2563..4074)
                     /locus_tag="ACL29Z_001393"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004191872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfcC family protein"
                     /protein_id="HGR0069688.1"
                     /translation="MSEKAKKGFKMPSSYTVLLIIIAIMAVLTWFIPAGAFIEGIYET
                     QPQNPQGIWDVLMAPIRAMLGTHPEEGSLIKETSAAIDVAFFILMVGGFLGIVNKTGA
                     LDVGIASIVKKYKGREKMLILVLMPLFALGGTTYGMGEETMAFYPLLVPVMMAVGFDS
                     LTGVAIILLGSQIGCLASTLNPFATGIASATAGVGTGDGIVLRLIFWVTLTALSTWFV
                     YRYADKIQKDPTKSLVYSTRKEDLKHFNVEESSSVESTLSSKQKSVLFLFVLTFILMV
                     LSFIPWTDLGVTIFDDFNAWLTGLPVIGNIVGSSTSALGTWYFPEGAMLFAFMGILIG
                     VIYGLKEDKIISSFMNGAADLLSVALIVAIARGIQVIMNDGMITDTILNWGKEGLSGL
                     SSQVFIVVTYIFYLPMSFLIPSSSGLASATMGIMAPLGEFVNVRPSLIITAYQSASGV
                     LNLIAPTSGIVMGALALGRINIGTWWKFMGKLVVAIIVVTIALLLLGTFLPFL"
     gene            complement(4285..5232)
                     /gene="arcC"
                     /locus_tag="ACL29Z_001394"
     CDS             complement(4285..5232)
                     /gene="arcC"
                     /locus_tag="ACL29Z_001394"
                     /EC_number="2.7.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003025409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008804 - carbamate kinase activity
                     [Evidence IEA];
                     GO_process: GO:0006520 - amino acid metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbamate kinase"
                     /protein_id="HGR0069689.1"
                     /translation="MANRKIVVALGGNAILSSDPSAKAQQEALVETAKHLVKLIKNGD
                     DLIITHGNGPQVGNLLLQHLASDSEKNPAFPLDSLVAMTEGSIGFWLKNALQNALLDE
                     GIEKNVASVVTQVIVDKNDPAFVNLSKPIGPFYSEEEAKAEAEKSGATFKEDAGRGWR
                     KVVASPKPVDIKEIETIRTLLNSGQVVVAAGGGGIPVVKENNGHLTGVEAVIDKDFAS
                     QRLAELVDADLFIVLTGVDYVFVNYNKPNQEKLEHVNVAQLEEYIKQDQFAPGSMLPK
                     VEAAIAFVNGRPEGKAVITSLENLGALIESESGTIIEKG"
     gene            complement(5397..6413)
                     /gene="argF"
                     /locus_tag="ACL29Z_001395"
     CDS             complement(5397..6413)
                     /gene="argF"
                     /locus_tag="ACL29Z_001395"
                     /EC_number="2.1.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003073325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004585 - ornithine carbamoyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0042450 - arginine biosynthetic process via
                     ornithine [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ornithine carbamoyltransferase"
                     /protein_id="HGR0069690.1"
                     /translation="MTNSVFQGRSFLAEKDFTRAELEYLIGLSAHLKDLKKRNIQHHY
                     LAGKNIALLFEKTSTRTRAAFTTAAIDLGAHPEYLGANDIQLGKKESTEDTAKVLGRM
                     FDGIEFRGFSQRMVEELAEFSGVPVWNGLTDEWHPTQMLADYLTVQENFGRLEGLTLV
                     YCGDGRNNVANSLLVTGAILGVNVHIFSPKELFPEKEIVELAEGFAKESGAHVLITED
                     ADEAVKDADVLYTDVWVSMGEEDKFAERVALLKPYQVNMDLVKKAGNENLIFLHCLPA
                     FHDTHTVYGKDVAEKFGVEEMEVTDEVFRSKYARHFDQAENRMHTIKAVMAATLGNLY
                     IPKV"
     gene            complement(6471..7700)
                     /gene="arcA"
                     /locus_tag="ACL29Z_001396"
     CDS             complement(6471..7700)
                     /gene="arcA"
                     /locus_tag="ACL29Z_001396"
                     /EC_number="3.5.3.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000094613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016990 - arginine deiminase activity
                     [Evidence IEA];
                     GO_process: GO:0019546 - arginine deiminase pathway
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="arginine deiminase"
                     /protein_id="HGR0069691.1"
                     /translation="MSSHPIQVFSEIGKLKKVMLHRPGKELENLLPDYLERLLFDDIP
                     FLEDAQKEHDAFAQALRDEGIEVLYLEQLAAESLTSPEIRDQFIEEYLDEANIRDRQT
                     KVAIRELLHGIKDNQELVEKTMAGIQKVELPEIPDEAKDLTDLVESEYPFAIDPMPNL
                     YFTRDPFATIGNAVSLNHMFADTRNRETLYGKYIFKYHPIYGGKVDLVYNREEDTRIE
                     GGDELILSKDVLAVGISQRTDAASIEKLLVNIFKKNVGFKKVLAFEFANNRKFMHLDT
                     VFTMVDYDKFTIHPEIEGDLHVYSVTYENEKLKIVEEKGDLAELLAQNLGVEKVHLIR
                     CGGGNIVAAAREQWNDGSNTLTIAPGVVVVYDRNTVTNKILEEYGLRLIKIRGSELVR
                     GRGGPRCMSMPFEREEV"
     gene            8455..10134
                     /locus_tag="ACL29Z_001397"
     CDS             8455..10134
                     /locus_tag="ACL29Z_001397"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000721501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-L-fucosidase"
                     /protein_id="HGR0069692.1"
                     /translation="MKKIKPHGPLPSQTQLAYLGDELAAFIHFGPNTFYDQEWGTGQE
                     DPERFNPSQLDAREWVRVLKETGFKKLILVVKHHDGFVLYPTAHTDYSVKVSPWRRGK
                     GDLLLEVSQAATEFDMDMGVYLSPWDAHSPLYHVDREADYNAYYLAQLKEILSNPNYG
                     NAGKFAEVWMDGARGEGAQKVNYEFEKWFETIRDLQGNCLIFSTEGTSIRWIGNERGY
                     AGDPLWQKVNPDKLGTEAELDYLQHGDPSGTIFSIGEADVSIRPGWFYHEDQDPKSLE
                     ELVEIYFHSVGRGTPLLLNIPPNQAGLFDAKDIERLYEFATYRNELYKEDLALGAEVS
                     GPTLSADFACRHLTDGLETSSWASDADLPIQLELDLGSPKTFDVIELREDLKLGQRIA
                     AFHVQVEVDGVWQEFGRGFTVGHKRLLRGPLVEAQKVRVMITEAQSMPLLTKISLYKT
                     PGLSKKEVVQELAFAEKSLAVAKGETLHFRIERSESSSSLEAKISIQPGTGVHGVAYQ
                     DEIQVLQFQAGESKKDLHLPTLYFAGDKTLDFYLNLTVDGQLVDQLQVQVS"
     gene            complement(10174..12258)
                     /locus_tag="ACL29Z_001398"
     CDS             complement(10174..12258)
                     /locus_tag="ACL29Z_001398"
                     /EC_number="3.2.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000803403.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030246 - carbohydrate binding [Evidence
                     IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GH92 family glycosyl hydrolase"
                     /protein_id="HGR0069693.1"
                     /translation="MKPLLETIDTRFGTASKHAFSRGNTLPYTGVPFGMNYFVPQTSD
                     QDGAWFFDPHLPIFQGIRLTHQPSPWIGDYSWLLLTPVTSQLGGDSLFHRQSSYDRDK
                     ASFQPHYLKIFSLRYQIETQLTPTCYGASIRLKQKQGKALSLYLHATDELTVEQVDKR
                     TLALRQEGKTETNKNSLTMFTALQMNTDILAISQEAGDWRIDLASSQTEMQLATSFIS
                     PSQALINLPQEDFDSCKASAQADWENLLHRFDVIETGEANRTFFDHCLYRLFLFPQTF
                     YEVDESGQAIHMDLATGTVKPGVLFSNNGFWDTFRTTFPLFALIIPEHYQRFLEGFLN
                     SYRDTGFLPKWLAPDERGMMPGTLLDGIIADSACKDMTPDLEGELFQAMLETASKADP
                     LGINGRHGLAQYQELGYLSTDHHESVSHTLDYAYSDFCIASCAKKLENIEIAETYKAA
                     SQNYRQLFDAETGYMRARDNQGNFHPDFSPYSWGRDYAECSAIQATLGVLHDIPGLIQ
                     LMGGKETFSNYLLKACQDAPLFETTGYGYEIHEMSEMATAPFGQIAISNQPSFHIPYL
                     FRYSDYPDYTALLIKTLRQKAFHPSWEAYPGDEDNGSLSAWYIWSALGFYPTCPGKPS
                     YDLGIPLFDHLRVYLAKEDKWLDIHTKQNHSHFNFVKECRLDKTLVSTIQHQDLLKAE
                     QLTFTLSWLPNH"
     gene            12429..13709
                     /locus_tag="ACL29Z_001399"
     CDS             12429..13709
                     /locus_tag="ACL29Z_001399"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 125 protein"
                     /protein_id="HGR0069694.1"
                     /translation="MIYSKEIVREWLDEVAERAKDHPEWVDVFERCYTDTLDNTVEIL
                     EDGSTFVLTGDIPAMWLRDSTAQLRPYLHVAKRDALLRQTIAGLVKRQMTLVLKDPYA
                     NSFNIEENWKGHHETDHTDLNGWIWERKYEVDSLCYPLQLAYLLWKETGETSQFDETF
                     VAATKEILHLWTVEQDHKNSPYRFVRDTDRKEDTLVNDGFGPDFAVTGMTWSAFRPSD
                     DCCQYSYLIPSNMFAVVVLGYVQEIFAALNLADSQSVIADAKRLQDEIQEGIENYAYT
                     TNSKGEKIYAFEVDGLGNASIMDDPNVPSLLAAPYLGYCSVDDEVYQATRRTILSPEN
                     PYFYQGEYASGLGSSHTFYRYIWPIALSIQGLTTRDKAEKKFLLDQLVACDGGTGLMH
                     ESFHVDDPTLYSREWFSWANMMFCELILDYLDIR"
     gene            13800..16445
                     /locus_tag="ACL29Z_001400"
     CDS             13800..16445
                     /locus_tag="ACL29Z_001400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000432759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-mannosidase"
                     /protein_id="HGR0069695.1"
                     /translation="MENVVVHIISHSHWDREWYLPFESHRMQLVELFDNLFDLFENDP
                     EFKSFHLDGQTIVLDDYLQIRPENRDKVQRYIDEGKLKIGPFYILQDDYLISSEANVR
                     NTLIGQQEAAKWGKSTQIGYFPDTFGNMGQAPQILQKSGIHVAAFGRGVKPIGFDNQV
                     LEDEQFTSQFSEMYWQGVDGSRVLGILFANWYSNGNEIPVDKDEALTFWKQKLSDVRA
                     YASTNQWLMMNGCDHQPVQKNLSEAIRVANELFPDVIFVHSSFDEYVQAVEGALPEHL
                     STVTGELTSQETDGWYTLANTSSSRIYLKQAFQENSNLLEQVVEPLTIITGGHNHKDQ
                     LTYAWKTLLQNAPHDSICGCSVDEVHREMETRFAKVNQVGNFVKSNLLNEWKGKIATD
                     KAQSDYLFTVINTGLHDKVDTVSTVIDVATCDFKELHPTEGYKKMAALILPSYRVEDL
                     DGRPVEATIEDLGANFEYDLPKDKFRQARIARQVRVTIPVHLAPLSWTTFQLLEGKQE
                     HREGIYQNGVIDTPFVTVSVDDNITVYDKTTHEAYEDFIRFEDRGDIGNEYIYFQPKG
                     TEPIFAELKGHEVLENTDRYAKILLKHELTVPVSADEKLEEEQQGIIEFMKREAGRSE
                     ELTNIPLETELIVFVDNPQIRFKTRFTNTAKDHRIRLLVKTHNTRPSNDSESIYEVVT
                     RPNKPAASWENPENPQHQQAFVSLYDDEKGVTVSNKGLNEYEILGDNTIAVTILRASG
                     ELGDWGYFPTPEAQCLREFEVEFAIECHQAQERFSAYRRAKALQTPFTSLQLARQEGS
                     VVATGSLLSHSVLSIPQVCPTAFKVAENEEGYVLRYYNMSQENVRISEHQQTILDLLE
                     RPYPVHSGLLAPQEIRTEFIKKEEI"
     gene            16529..17398
                     /locus_tag="ACL29Z_001401"
     CDS             16529..17398
                     /locus_tag="ACL29Z_001401"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HGR0069696.1"
                     /translation="MTIATIDIGGTGIKFASLTPDGKILDKTSISTPENLEDLLAWLD
                     QRLSEQDYSGIAMSVPGAVNQETGVIDGFSAVPYIHGFSWYEALSSYQLPVHLENDAN
                     CVGVSELLAHPELENAACVVIGTGIGGAMIINGRLHRGRHGLGGEFGYMTTLAPAEKL
                     NNWSQLASTGNMVRYVIEKSGHTDWDGRKIYQEAATGNALCQEAIERMNRNLAQGLLN
                     IQYLIDPDVISLGGSISQNPDFIQGVKKAVDNFVDAYEEYTVAPVIQACTYHADANLY
                     GALVNWLQEEKQW"
     gene            17392..19272
                     /locus_tag="ACL29Z_001402"
     CDS             17392..19272
                     /locus_tag="ACL29Z_001402"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-N-acetylhexosaminidase"
                     /protein_id="HGR0069697.1"
                     /translation="MVRFIGLSPKQTQAIEVLKGHISLPDVEVAVTQSDQASISIEGE
                     EGHYQLTYRKPHQLYRALSLLATVLAEADKVEIEEQAAYEDLAYMVDCSRNAVLNVAS
                     AKQMIEVLALMGYSTFELYMEDTYQIEGQPYFGYFRGAYSAEELQEIEAYAQQFDMTF
                     VPCIQTLAHLSAFVKWGVKEVQELRDVEDILLIGEEKVYDLIDGMFATLSKLKTRKVN
                     IGMDEAHLVGLGRYLILNGVVDRSLLMCQHLERVLDIADKYGFHCQMWSDMFFKLMSA
                     DGQYDRDVEIPEETRVYLDRLKDRVTLVYWDYYQDSEEKYNRNFRNHHKISHDLAFAG
                     GAWKWIGFTPHNHFSRLVAIEANKACRANQIKEVIVTGWGDNGGETAQFSILPSLQIW
                     AELSYRNDLDSLSAHFKTNTGLTVEDFMQIDLANLLPDLPGNLSGINPNRYVFYQDVL
                     CPILDRHMTPEQDKPHFAQAAGTIADIKEKAGNYAYLFETQAQLNAILSSKVDVGRRI
                     RQAYQADDKESLQQIARQELPELRSQIEDFHALFSHQWLKENKVFGLDTVDIRMGGLL
                     QRIKRAESRIEVYLAGQLDRIDELEVEILPFTDFYADKDFAATTANQWHTIATASTIY
                     TT"
     gene            19598..19915
                     /locus_tag="ACL29Z_001403"
     CDS             19598..19915
                     /locus_tag="ACL29Z_001403"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0069698.1"
                     /translation="MILWSFDFANDHAHAFFMDNVEWSHADSYFLSFVSDDVEERYTE
                     NVYLDSLSVKQKFKFIFDFGDEWRFECQVLREIETEDEEAYLVRSVGTSPEQYPDYDG
                     FDY"
     gene            complement(19979..20828)
                     /locus_tag="ACL29Z_001404"
                     /pseudo
     CDS             complement(19979..20828)
                     /locus_tag="ACL29Z_001404"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="programmed frameshift; internal stop; incomplete;
                     partial in the middle of a contig; missing C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS5 family transposase"
     gene            complement(20773..20955)
                     /locus_tag="ACL29Z_001405"
     CDS             complement(20773..20955)
                     /locus_tag="ACL29Z_001405"
                     /inference="COORDINATES: protein motif:HMM:NF016232.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding domain-containing protein"
                     /protein_id="HGR0069699.1"
                     /translation="MDLKFEGVDLEYKKAKNNLPESFWETYSAFANTNGEKIILGIDE
                     KNIDTYQRVNRLPAKL"
     gene            21290..>22716
                     /gene="pcpA"
                     /locus_tag="ACL29Z_001406"
     CDS             21290..>22716
                     /gene="pcpA"
                     /locus_tag="ACL29Z_001406"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000753909.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline-binding protein PcpA"
                     /protein_id="HGR0069700.1"
                     /translation="MKKTTILSLTTAAVILAAYVPNEPILADTPSSEVIKETKVGSII
                     QQNNIKYKVLTVEGNIGTVQVGNGVTPVEFEAGQDGKPFTIPTKITVGDKVFTVTEVA
                     SQAFSYYPDETGRIVYYPSSITIPSSIKKIQKKGFHGSKAKTIIFDKGSQLEKIEDRA
                     FDFSELEEIELPASLEYIGTSAFSFSQKLKKLTFSSSSKLELISHEAFANLSNLEKLT
                     LPKSVKTLGSNLFRLTTSLKHVDVEEGNESFASVDGVLFSKDKTQLIYYPSQKNDESY
                     KTPKETKELASYSFNKNSYLKKLELNEGLEKIGTFAFADAIKLEEISLPNSLETIERL
                     AFYGNLELKELILPDNVKNFGKHVMNGLPKLKSLTIGNNINSLPSFFLSGVLDSLKEI
                     HIKNKSTEFSVKKDTFAIPETVKFYVTSEHIKDVLKSNLSTSNDIIVEKVDNIKQETD
                     VAKPKKNSNQGVVGWVKDKGLWYYL"
BASE COUNT         6737 a         4476 c         4955 g         6548 t
ORIGIN      
        1 ttatctacta cctcaaaacg gtgttttgag caacctgtgg ctagtttcct agtttactat
       61 ttgattttca ttgagtacaa agagcttggc aacaggctct ttttgtattg cgtttattaa
      121 gaaaaacaaa aaacatagat atacatttaa ctaaaaatta ttgtatgtta tctcccttaa
      181 ttaggaatga taagggaata actagaaaga tttgtgaata caaactattt ctgatataca
      241 aaatatacag taataatgaa tgatgggaga tgggatgaaa gaatttcaat ttgagagaaa
      301 gcagcgtttt tctttgagga aatatgcaat aggagcttgt tcggtcttgc taggaacgag
      361 tttatttttt gctggtatgg gtgctcagcc tgtacaggat acagaaacga gttcagcact
      421 aatttcaagt cattatttgg atgagcagga tttatctgaa aagctgaaat ctgagttgca
      481 atggtttgaa ttagaaaaca agcttttgaa cttatgggag cattaggtta ctatgaagga
      541 tttgttcctt atgtttcaaa tcaatacaaa aaccaagctg aagaagaagg caaaccgcta
      601 tctgataaat atattttcga aaaaatctta ggaaaaacat atgcagcctt caaaaaaaga
      661 tcaaattaat gagcgtgtcg agaaattagg taagttaaaa cctattacaa taaattacaa
      721 cggaaaatca gaagtaattg atagtaaaga aaaattacaa gagcttatga ataaagccgt
      781 taaagacgaa gtggctcaaa tatagtaaaa tgaaataaga acaggacaaa tcgatcagga
      841 cagtcaaatc gatttctaaa aatgttttag aagtagaggt gtactattct agtttcaata
      901 tactataaaa tcaggcaata ccacggctaa aaagtttgag tttatcgaaa caccagtgca
      961 aaaactgaaa aaagcgattt ataaagctca tctcaaagat tcagatgact ttagaccaga
     1021 aacatccaca caaatctttt tgaaagctgt ttgaagcttt gtccttgctt tcttagttca
     1081 tagatctgaa ctttatcttc ataattcaat ttcataataa aacaccccaa aagttagatt
     1141 tattctgtct aacttttggg gtgcagttca ttaatcggtc gatttttttt ggtagaaaca
     1201 gttgcctgat taagttgcaa gtcgatagac ggcttcggca taaatatcca tagcacggta
     1261 caaatcttct agaacggcac attcatttgc ctgatgttct gtctgcttcg ctcctgggaa
     1321 taaggcgccg aaggctacac aatttggcat ggtgcgagca aaagtggcac caccggatga
     1381 aatagcagga ctgttatcgc cagtcttttc ttggtagatt tgcatcagtg tgctaacgag
     1441 tttactgtct tttgcgacgt atagaggcgc tagatagtca aactcttcgt agcggagttg
     1501 gtagttttgt gcacatcttg taagcaactc tactagttct tccttgtcag ctaagacagg
     1561 agtccgaatg tcaatacgga tttcagaacg ttcatgattg atcatgagac ctgcgacatt
     1621 aaaggatagg tgaccagaag gttcatctgc tatatcacca aagatttgtc ttcctgtgcc
     1681 gtcttgacct gcttgtgttg caagaaaact gagagcaggg tgttcttgga gaggagcaag
     1741 aatggtagct agtcggatga cagcattgat accttgacta gcatccttag catgctttgg
     1801 cactccgaga accgttacgg tttgttcagt ggattggtaa tcataaccag cttctttgag
     1861 accgttacaa acctgttcat agaggggacc ttggtagttg gccttgtctg gtacaacgtt
     1921 aaaggcgcct cctacttcaa gctctagttg atccgatcca gagccataaa gtttgacctg
     1981 tagaagccct ttttcagcat aggtcagagg aaaagatgag tcaggtgcaa agcccatact
     2041 ggcctgttct tcgatggtat tgtagcgtgc catgcagcgc cagagggttt cctcatcggt
     2101 accaaagata aagcgtacgc gctttttgaa ctgaatacct tggtccagca agctttttac
     2161 tgcatagaga gctgcgagcg aagggccttt atcatcttgg acaccacgtc cgaataccca
     2221 gccgtctttg atagttgctt caaatggcgg tgtctgccaa tctgcttcat cacctgatgg
     2281 aacaacatcc aaatgacaga gaatggccag aagctctgct ccctgaccga tttctgcata
     2341 tccgtaataa cctttagggt caagataggt agtgaaacct atgtctcgac aaatctctaa
     2401 agttttttct aggacatctt ggattgcttg tccaaaaggt gttccatttt ctccttcatt
     2461 gagtactgaa ggataggaaa tcaaggtttt taatgatata agaaattcat ctttaacttg
     2521 atttgttata tctattttca tggaatcacc tcactcacta ttttatagga atggaaggaa
     2581 ggttccaagg agaagaaggg cgatggtcac tacaataata gcgactacga gtttgcccat
     2641 gaatttccac caagtaccaa tgttgatacg tccaagtgca agagctccca tcacaatacc
     2701 agatgttggt gcaatcaagt tcaagacacc tgaagcagat tggtaagcag tgataatcaa
     2761 gctaggacgg acatttacaa attctccaag tggagccatg atacccatag ttgcgctggc
     2821 aagaccagat gaagatggga tcaagaatga cataggtaga tagaagatat aagttacaac
     2881 gataaagact tgtgaagata gaccgctcaa gccttcttta ccccagttga ggattgtatc
     2941 ggtaatcata ccgtcgttca tgataacttg aataccacga gcaatcgcta cgatcaaggc
     3001 aacactgagc aagtcagcag caccattcat gaaggaagag ataatcttat cttctttaag
     3061 accataaata acaccaatca ggatacccat aaaggcaaag agcattgcgc cttctgggaa
     3121 gtaccaagta cctagtgcag aagtagatga accgacaata ttaccaataa ctggaagacc
     3181 agtcaaccaa gcattaaagt catcaaaaat ggtaacgcca aggtctgtcc atggaatgaa
     3241 gctcaatacc atcaagatga atgtcaacac aaataagaag agaactgatt tttgtttgct
     3301 gctaagtgta gattctacag atgaagattc ttccacgtta aagtgtttta aatcttcttt
     3361 gcgagtacta taaaccagtg acttagtcgg atctttttga atcttatccg cataacggta
     3421 aacaaaccaa gtactaagag cagtcaaggt aacccagaag atcagacgaa gtacgatacc
     3481 gtcccctgta ccaactcccg cagtcgctga agcaatacct gtcgcaaatg gattcagagt
     3541 agatgccaaa cagccgattt gagaaccgag caaaataatt gcaacaccag tcaggctatc
     3601 aaaaccaacg gccatcataa ctggcacaag gagtggatag aaggccattg tttcttcacc
     3661 cataccataa gttgtaccac cgagggcaaa caaaggcatt agtaccaaaa ttaacatttt
     3721 ttcgcggccc ttatacttct tcacgataga ggcaatccct acgtcaagag caccagtttt
     3781 gttgacaatg ccaaggaaac caccaaccat aaggatgaag aaggctacat caatcgctgc
     3841 gctcgtttct ttaatgagcg aaccttcctc tggatgagta cctagcatag cccgaatcgg
     3901 tgccatgagg acatcccaaa tcccttgtgg attttgaggc tgagtctcgt aaataccttc
     3961 tataaaggcc cccgcaggga taaaccaagt tagtactgcc ataatagcaa tgattatcaa
     4021 taatacggtg taagatgaag gcatcttaaa ccctttttta gctttttcac tcatttgttt
     4081 ttcctcctga tgtctaacaa agtgtaaaaa accaactact ttcttaaata aacatttaag
     4141 aaaacgcttt ctatttatat ttgttttacc atattaaagt ctaaaaaact aatatctttt
     4201 gaaatattgt acatgttttc aagaataatt tctaatttga tataaagata ctagaaatag
     4261 aatacatctt attagtaaaa caacttatcc tttttcaata attgttccac tttcagattc
     4321 aatcaaggcg cctagatttt caagggaagt aataactgct tttccttctg gacgaccatt
     4381 gacaaaagcg atagctgctt ctacttttgg aagcatgcta cctggtgcaa actgatcttg
     4441 tttgatatat tcttccagct gggcaacatt cacatgttcc aatttttcct ggtttggctt
     4501 gttgtagtta acaaatacat aatctacacc tgtcaaaacg atgaagaggt ctgcatcaac
     4561 caattctgcc aaacgttggg aagcgaagtc tttatcaata accgcttcga caccagtcaa
     4621 atgtccattg ttttctttga cgacgggaat accgccacca cctgcagcta cgacgacttg
     4681 accactattt aaaagagtac ggatggtttc aatttctttg atgtcaacag gttttggtga
     4741 ggcaacgacc ttacgccagc cacggccagc atcttccttg aaagtcgctc cgctcttttc
     4801 ggcttctgct tttgcttctt cttctgaata gaaaggaccg attggtttac tcaagttaac
     4861 aaaagctgga tcatttttat ctacgataac ttgcgttaca acagaggcaa catttttttc
     4921 gatgccttca tccaagagag cattttgcaa agcatttttc aaccagaaac cgatgctacc
     4981 ttctgtcata gcgacaagtg agtcgagtgg gaaggcaggg ttcttttcag agtctgatgc
     5041 caaatgttgg agcaagagat tcccaacttg aggtccatta ccgtgagtga taatcaaatc
     5101 atctccattt ttaatcaatt ttacaagatg cttagctgtt tcaactaaag cttcttgttg
     5161 agcctttgct gatgggtcag aagaaagaat cgcatttcct cccaaagcta ctacaatttt
     5221 acgatttgcc ataaattctc ctttatcaca ctcaatagaa tgcgtttaga tttcaattta
     5281 atgatttttc acatatttta taagaaataa tagattacca ttatataaaa gaggaccgga
     5341 ctaaagctat tagtcgcagc cctcatagct gttggtagac ggtttattat ctaaaattat
     5401 actttaggaa tataaaggtt accaagtgtc gcagccataa cagctttgat agtgtgcata
     5461 cggttttctg cttgatcgaa gtggcgagcg tacttgctgc ggaagacttc gtctgttact
     5521 tccatttctt ctacaccaaa tttttcagca acgtctttac cataaacagt gtgagtatcg
     5581 tggaatgctg gcaagcagtg taggaagatc aagttttcat tgcctgcttt tttaactaag
     5641 tccatattga cttggtaagg tttaagaaga gctacacgtt ctgcgaattt gtcttcttca
     5701 cccattgata cccaaacgtc tgtgtaaaga acgtctgcat ctttaactgc ttcatcagca
     5761 tcttcagtga tgagaacatg tgcgccactt tctttagcaa atccttctgc caattcaacg
     5821 atttcttttt ctgggaagag ttcttttggt gagaagatgt gaacattgac accaaggata
     5881 gcacctgtta cgagcaagct gttggcaacg ttgttacgtc catcaccaca gtataccaat
     5941 gtcaagcctt ccaagcgacc gaagttttct tgaacagtca agtagtcagc gagcatttga
     6001 gttgggtgcc attcgtcagt tagaccgttc catactggaa cgcctgagaa ttctgccaat
     6061 tcttcaacca tacgttggct gaatccgcgg aattcaatcc cgtcaaacat acgtcccaat
     6121 actttagcag tatcttcagt agattctttt ttacccaact gaatatcatt tgctccgagg
     6181 tattctgggt gagcaccaag gtcgatagcc gcagttgtaa aggctgcacg agtacgagta
     6241 gatgtttttt caaataggag agcgatattc ttgccagcaa gatagtggtg ttgaatattg
     6301 cgttttttca aatctttcaa gtgagctgaa agaccaataa ggtattctaa ctctgcacgg
     6361 gtaaagtctt tttctgctaa gaagctgcgt ccttggaata ctgaatttgt cattttatta
     6421 tttcctcttt ctatttttta cattttctat tgacgaatgc cgaacagcga ttacacttct
     6481 tcacgttcaa atggcataga catacaacga ggtccaccac ggccccgaac caattcactt
     6541 ccgcgaatct taatcaagcg aagcccgtat tcttccaaaa tcttattggt cacggtattg
     6601 cggtcataaa caactaccac accaggtgcg atggtcaaag tgttagaacc gtcgttccat
     6661 tgttcacgcg cagctgctac gatattgcca ccaccgcaac gaatcaaatg aactttttct
     6721 acaccaaggt tttgagcaag aagttcagct aagtcacctt tctcttcaac gattttaagt
     6781 ttttcgtttt cgtaagtaac tgagtaaacg tgaaggtcgc cttcgatttc tgggtgaata
     6841 gtgaacttgt catagtctac catagtgaag acagtatcca agtgcatgaa tttacggttg
     6901 ttagcaaatt caaaggccaa aactttcttg aagccaacat ttttcttgaa gatgttgacc
     6961 aaaagttttt cgatagaagc tgcgtctgta cgttgagaga tacctactgc aaggacgtct
     7021 ttagaaagaa ttagctcgtc tccaccttcg atacgcgtat cttcttcacg gttgtagacc
     7081 aaatccactt ttccgccata gattgggtgg tatttgaaga tatacttacc gtagagtgtt
     7141 tcacggttac gagtatctgc aaacatgtgg ttaagcgata cggcgtttcc aattgttgca
     7201 aatgggtcgc gagtgaaata gaggtttggc atcgggtcaa ttgcaaatgg atactctgat
     7261 tcaactaagt cagttagatc tttagcttcg tcaggaattt ctggcaattc aactttttga
     7321 atcccagcca ttgttttttc aaccaattct tggttgtcct tgatgccgtg aagcaattca
     7381 cgaatagcaa ccttagtttg acgatcacgg atgttggctt cgtctaagta ttcctcgata
     7441 aattgatcgc ggatttctgg agaggtcaat gattcagcag cgagttgttc taggtagaga
     7501 acctcaattc cttcatcgcg aagagcttgg gcaaatgcat catgttcttt ttgagcatct
     7561 tccaagaaag gaatatcatc aaaaagaagc ctttcaagat agtccggcaa caagttttct
     7621 aactccttgc ctggacggtg caacataact tttttcagtt tcccaatttc tgagaagacc
     7681 tgaattggat gagaagacat gtattttcct ccttaaaaat tttgacttgg caccattttg
     7741 ggtaccgctt acatgtatgt tataacgcaa ttcctaggta atgtcaatgg ctataatttc
     7801 tcggaaaata atataaatta tgatgtttag cacaatttta tgttattata cataacatag
     7861 gatagaatac atagatacaa atgcataaac ttctataaaa aggatataaa atttttttaa
     7921 aaaatttttc aaaaaatata caaatgacca aaaagtgtcc aattatcatc tggttatcac
     7981 ttggatctgt ataaagagaa atgtttgtgt gaaaggataa aaagatgcaa cattcttttg
     8041 aagatagatt ttggagaagc atttcttgtt caattgtaca aattatagaa tcttttctga
     8101 gtatttagga agagataatt atcttattga ccctcttttt attttttgtt atagtcgacg
     8161 aggtgatagc ttagaataat cacttattca caatctgtgg aaaagtctgg agagtgaatg
     8221 gtcttcacac aatgacctga aagaagcctg agaataatta tggagagtag cattctgaga
     8281 ggtgttagca gaaccatatg acagagctgt ttgaagaggg aatattgagg agcaaaatcc
     8341 tgagcctacc agttggagtt ggaaagagct ggctgttaga tcatggttta ttatccacaa
     8401 cctgtggata accttgtgaa caagagaagt tgctaaagaa ggagatatat aacgatgaag
     8461 aaaatcaaac cgcatggacc gttaccaagt cagactcagc tagcttatct gggagatgaa
     8521 ctagcagctt ttatccactt cggtcctaat accttttatg accaagaatg ggggactgga
     8581 caggaggatc ctgagcgctt taacccgagt cagttggatg cgcgtgagtg ggttcgtgtg
     8641 ctcaaggaaa cgggcttcaa aaagttgatt ttggtggtca agcaccacga tggctttgtc
     8701 ctttatccga cagctcacac agattattcg gttaaggtca gtccttggag gagaggaaag
     8761 ggcgacttgc tccttgaagt atcccaagct gccacagagt ttgatatgga tatgggggtc
     8821 tacctgtcac cgtgggatgc ccatagtccc ctctatcatg tggaccgaga agcggactac
     8881 aatgcctatt atctggctca gttgaaggaa atcttatcaa atcctaacta tgggaatgct
     8941 ggtaagttcg ctgaggtttg gatggatggt gccagaggag agggcgcgca aaaggttaat
     9001 tatgaatttg aaaaatggtt tgaaaccatt cgtgacctgc agggcaattg cttgattttt
     9061 tcaacagaag gcaccagtat ccgatggatt ggcaatgaac gagggtatgc aggtgatcca
     9121 ctgtggcaaa aggtgaatcc tgataaacta ggaacagaag cagagctgga ctatcttcag
     9181 cacggggatc cctcgggcac gattttttca atcggagagg cagatgtttc catccgtcca
     9241 ggctggttct accatgagga tcaggatcct aagtctctcg aggagttggt cgaaatctac
     9301 tttcactcag tagggcgagg aactccactc ttgcttaata ttccgccgaa tcaagctggg
     9361 ctctttgatg caaaggatat tgaacgactt tatgaatttg cgacctatcg caatgagctc
     9421 tataaagaag atttggctct gggagctgag gtatctggtc caactctttc cgcagacttt
     9481 gcttgtcgcc atttgacaga cggccttgag accagctctt gggcaagcga tgcagacttg
     9541 cccatccagt tagaactcga cttaggttct cctaaaactt ttgatgtaat tgagttaaga
     9601 gaagatttga agctagggca acgaatcgct gctttccatg tgcaagtaga ggtggatggt
     9661 gtctggcagg aatttggcag gggcttcaca gttggtcata agcgcctctt gcgaggtccg
     9721 ctagtagagg cacagaaggt gcgcgtgatg attaccgaag cacaatctat gcctctactg
     9781 accaagattt ccctttataa aactcctggg ttatcaaaaa aagaagttgt tcaggaacta
     9841 gcatttgcag aaaaaagcct agctgtggca aagggagaga ctcttcattt taggattgaa
     9901 cgtagtgaaa gtagctcctc tttagaggct aagatttcga ttcaaccggg gacaggtgtc
     9961 catggtgtcg cctatcagga tgagattcaa gtccttcaat tccaagcagg ggaaagcaaa
    10021 aaagatttgc atctaccaac cctgtatttc gcaggagata aaaccttgga tttctatctg
    10081 aacctaacgg tggatggtca gcttgtggat caacttcaag tccaagtttc ataaaagaag
    10141 aacctttgcg cgatgcaaag gttcttttgg ttattagtga tttggtagcc agctgagggt
    10201 gaaagttagt tgttcagctt ttaggaggtc ttggtgttga atagttgata cgagtgtttt
    10261 gtccagtcgg cattctttga caaagttaaa atggctgtgg ttttgtttag tatggatatc
    10321 cagccattta tcttctttag ctaggtagac tcgtagatgg tcaaagagag ggattccgag
    10381 gtcatagctt ggttttcctg gacaggttgg ataaaatccg agagctgacc agatgtacca
    10441 agcagagaga ctaccattgt cttcatctcc aggataggct tcccaacttg ggtgaaaagc
    10501 tttctgacgg agcgtcttga taagaagggc agtgtagtca gggtaatcgc tgtagcggaa
    10561 gagataagga atgtggaaac taggctggtt ggaaatggct atttgcccaa aaggagcagt
    10621 agccatctcg ctcatttcgt gaatttcgta accatagcct gttgtttcaa agaggggagc
    10681 atcttgacag gctttcaaaa gatagttgct aaaggtttct tttccaccca tcagttggat
    10741 taagccaggg atgtcgtgga gaacgcctaa agtagcttga atggcagagc attcagcgta
    10801 gtctcgcccc caactataag gagagaagtc agggtgaaag tttccttgat tgtctcgtgc
    10861 tcgcatgtaa cctgtctcag cgtcaaatag ctggcggtaa ttttgtgaag cagccttgta
    10921 ggtttcagcg atttctatgt tctctagttt tttggcacag ctggcgatac aaaagtcact
    10981 ataggcatag tctagagtat ggctaacact ttcgtggtgg tcggtagaga ggtaacctag
    11041 ttcttggtat tgggctagtc cgtggcggcc attgatgccg agagggtcgg ctttgctggc
    11101 tgtttcgagc atggcttgga agagttctcc ttctaggtcg ggggtcatgt ccttgcaggc
    11161 gctatctgcg ataataccgt ctaaaagtgt acctggcatc ataccccgtt catctggagc
    11221 cagccatttt ggaaggaaac cagtatcgcg gtagctattg aggaaacctt ctaaaaagcg
    11281 ttgatagtgc tccggtatga taagggcaaa gagggggaag gtggtgcgga aggtatccca
    11341 gaaaccattg ttgctaaaga ggacaccagg cttgacagta ccagtagcca gatccatgtg
    11401 gatggcttgc cctgactcat caacctcata aaaagtctgt gggaagagga agagtctgta
    11461 gagacagtgg tcaaagaagg ttcggttagc ctctcctgtc tctataacat caaaacgatg
    11521 gaggagattt tcccaatccg cttgggcact tgctttacag ctatcaaaat cttcttgagg
    11581 tagattgatt agagcttgag aaggagagat gaaagaagtg gctagttgca tctcggtttg
    11641 actacttgct aagtcaattc gccagtctcc agcttcttgg ctgatagcaa gaatatccgt
    11701 gttcatttgc agggcagtga acatcgttag cgaatttttg ttggtttcag ttttaccttc
    11761 ttgtcgcagg gcaagagttc gcttatctac ttgctctact gtcagttcat ctgttgcgtg
    11821 aagatagagg gagagggctt tgccttgctt ttgcttcaaa cgaatagaag caccgtagca
    11881 agtcggtgtg agctgggttt caatctgata gcgcagggag aaaatcttta gataatgagg
    11941 ttggaaagag gccttatccc tatcatagga agattggcgg tgaaagaggc tgtctccacc
    12001 cagttgactg gtgacgggtg tcagaaggag ccaagagtag tccccgatcc aaggactggg
    12061 ctggtgagtt aatcgaatcc cctgaaagat aggcagatgc ggatcaaaaa accaagctcc
    12121 atcctggtca ctggtctggg gcacaaagta attcatccca aaaggcacgc ctgtgtatgg
    12181 cagggtattt ccccgagaaa aggcatgctt gctagcagta ccaaagcggg tatcgatggt
    12241 ttcaagtagt ggtttcatag tctttccttt agctgttttt ctacattata tcagaaaaag
    12301 agggccttta gaaaaggagt tttaaagata actattttgt agaaaaatga ctatcatttg
    12361 tgtatgtatt ttctgtctca aaagctatat actgaacatg aaacttgttt gaaagaggga
    12421 attgcacgat gatttattcg aaagaaattg ttagagaatg gctagatgaa gtagcagagc
    12481 gggccaagga ccatccagag tgggtggatg tttttgagcg ttgctacacc gataccttgg
    12541 acaatacggt tgaaatctta gaagatggtt caacttttgt cttgactggg gatattcctg
    12601 ccatgtggct tcgagattcg acagcccaac tcagacccta ccttcatgta gctaaaagag
    12661 atgccctcct gcgtcagacc attgcaggtt tggtcaaacg tcagatgacc ttggtactca
    12721 aggatcccta tgctaactcc ttcaacattg aggagaactg gaaagggcac cacgagactg
    12781 accacacaga ccttaacggc tggatctggg agcgcaagta tgaggtggat tcgctttgct
    12841 atcctttgca gttggcttat ctcctctgga aagagactgg cgagactagt cagtttgatg
    12901 aaacttttgt cgcagcgact aaggaaattc tccatctatg gacagttgaa caagaccaca
    12961 agaactctcc ttatcgtttt gtccgagata cggaccgtaa ggaagacacc ttggtaaatg
    13021 atggctttgg acctgacttt gcagtgacag gtatgacttg gtcagctttt cgtccgagtg
    13081 acgattgctg tcagtatagt tacttgattc cgtcaaatat gtttgctgta gtagtcttgg
    13141 gttatgtgca agaaatcttc gcagcattaa acctagctga tagccagagt gttattgctg
    13201 atgccaagcg tcttcaggat gaaatccaag aaggaatcga aaactacgct tacaccacca
    13261 acagcaaggg tgaaaagatt tatgcctttg aagtggatgg cctaggaaat gccagcatta
    13321 tggatgatcc aaacgtacca agtctactag ctgcgcccta tctgggctac tgttcggtcg
    13381 atgatgaagt gtatcaagct actcgccgta ccattctgag ccctgaaaat ccatatttct
    13441 accaaggaga atacgcaagc ggtctcggca gttctcatac cttctatcgc tatatctggc
    13501 caatcgccct ttctatccaa ggcttgacaa caagagataa ggcagagaaa aaattcttgc
    13561 tggatcagct ggttgcttgc gatggcggta caggtcttat gcatgaaagc ttccacgtgg
    13621 atgacccaac tctctactct cgtgaatggt tctcctgggc taacatgatg ttctgtgagt
    13681 tgatcttgga ttacttggat attcgctaag gggctcgctt tagctcaacc gattcttatc
    13741 agaatcacaa gtttacattt aaaacgttaa aatttaaatt tagaatgagg ttttacttca
    13801 tggaaaatgt tgttgtacat attatctcac atagtcactg ggaccgtgag tggtacttgc
    13861 cttttgaaag ccatcgtatg cagttggtgg aattgtttga caatctcttt gatctctttg
    13921 aaaatgaccc tgagttcaag agtttccact tggatggaca aactattgtc cttgatgact
    13981 acttacaaat tcgccctgaa aatcgcgaca aggtccaacg ctacattgac gagggcaaac
    14041 ttaaaattgg tcccttttac atcttgcagg atgactactt gatctccagt gaagccaatg
    14101 tccgcaatac cttgattggt caacaagaag ctgccaaatg gggtaaatca acccagattg
    14161 gctactttcc agataccttt ggaaatatgg gacaagcgcc tcaaattctt caaaaatcag
    14221 gcattcacgt ggcggccttt ggtcgtggtg tgaagccgat tggatttgac aaccaagtcc
    14281 ttgaagatga gcagtttaca tcccagtttt cagaaatgta ctggcagggt gtggatggta
    14341 gtcgtgtttt aggtattctc tttgccaact ggtacagtaa tgggaatgaa atcccagttg
    14401 acaaagatga ggccttgacc ttctggaaac aaaaattgtc agatgtgcgt gcctacgctt
    14461 cgaccaacca atggttgatg atgaacggct gtgaccacca gcctgtacag aaaaatctga
    14521 gcgaagccat tcgtgtggca aatgaactct tcccggatgt aatctttgtt catagttctt
    14581 ttgatgaata tgttcaagct gtagaaggtg cgcttcctga acacttatca actgttacag
    14641 gcgagttgac cagtcaggaa acagatggct ggtacacact tgccaacact tcttcatccc
    14701 gcatttacct aaaacaagcc ttccaagaaa atagcaacct cctagagcaa gtggtagaac
    14761 ccttgactat tatcactggt ggacacaacc acaaggacca gttgacctat gcttggaaaa
    14821 cacttttgca gaatgcgcca catgatagta tctgtggctg tagcgtggac gaagttcacc
    14881 gcgagatgga aacgcgtttt gccaaggtca accaagtagg aaactttgtt aaaagtaact
    14941 tgctcaacga gtggaagggt aaaattgcta cggataaggc tcaaagtgac tatctcttta
    15001 ctgtcattaa cacaggcttg catgataagg tcgatactgt cagcacagtg attgatgtgg
    15061 cgacttgtga tttcaaggaa ttgcacccaa cagaaggcta caaaaagatg gctgctctta
    15121 tcttaccaag ttaccgtgtg gaggacttgg atggtcgtcc tgtagaggct acaatcgaag
    15181 acctcggagc taattttgag tacgatttac caaaagacaa gttccgccaa gctcgtattg
    15241 ctcgacaagt gcgcgtgacc attccagttc acctagcgcc gctttcttgg acaaccttcc
    15301 aattgctgga aggaaaacaa gaacaccgtg agggtattta ccaaaacgga gtgattgata
    15361 caccattcgt aacggtgagt gtggatgaca atatcacagt atatgacaag acaactcacg
    15421 aagcctatga agactttatc cgcttcgaag accgtgggga catcggaaac gagtatatct
    15481 atttccaacc aaaaggaaca gagccaatct ttgcagagct taagggccac gaggtcttgg
    15541 aaaacacaga tcgctatgct aaaatcttgc tcaaacatga attgaccgtg cctgtcagtg
    15601 cggatgaaaa gctagaagaa gagcaacaag gtatcatcga gtttatgaag cgtgaggctg
    15661 gacggtcaga agaattgaca aacattcctc tggaaactga gttgattgtc tttgttgaca
    15721 atccacaaat ccgcttcaag actcgcttta ctaacactgc caaggatcac cgtatccgtc
    15781 tcttggtcaa gactcataac acgcgtccaa gcaatgattc tgaaagtatc tatgaggtgg
    15841 tgacacgacc aaacaaacca gctgcttcat gggaaaatcc tgaaaatcct caacaccaac
    15901 aagcttttgt cagtctgtat gacgatgaaa aaggggtgac tgtatccaac aagggattga
    15961 atgaatacga aatccttggg gataacacca ttgccgtgac cattttgcgt gcatcaggtg
    16021 agctaggtga ctggggctac ttcccaacgc cagaagcaca atgcttgcgt gagtttgaag
    16081 tcgaatttgc gattgaatgc caccaagccc aagaacgctt ctcagcctat cgtcgtgcca
    16141 aagccttgca gacaccgttt accagccttc agcttgctag acaggaagga agcgtggttg
    16201 cgactggtag cctcttgagc cattctgttc tcagcatacc gcaagtttgt ccaacagcct
    16261 ttaaagtggc ggaaaatgaa gaaggctatg tcctccgtta ctataatatg agtcaagaaa
    16321 atgtgcgcat atcagaacat caacaaacca ttcttgactt acttgagcga ccatatccag
    16381 ttcattcagg actattggct ccacaagaga ttcgtacaga attcatcaaa aaagaagaaa
    16441 tttaatttca aaaagtaaac atcaaaagaa aggaggggcg aaaaagtaag aactaactgc
    16501 tgattcgccc ctttttatgg taaaaacaat gaccattgca acgattgata tcggagggac
    16561 tgggattaag tttgccagtc tgactcctga tgggaaaata ctggataaga caagtatttc
    16621 aacgcctgaa aacttggagg atttactagc gtggctagat caacgcttgt cagaacagga
    16681 ttacagtggg attgctatga gcgttccagg tgcggtcaat caagagacag gtgtgattga
    16741 tggcttcagt gcggtgccct acatccatgg cttttcttgg tatgaggcgc ttagctctta
    16801 tcagctacct gtccatttag aaaatgatgc caactgcgtt ggagtcagtg aactactagc
    16861 tcatccagag cttgaaaatg cagcctgtgt cgtgattggg acagggattg gcggagccat
    16921 gattatcaat ggtagacttc atcgaggtcg ccacggtctg ggtggagaat ttggttacat
    16981 gacaaccctt gcccctgctg aaaaacttaa taactggtcg caactagcat caactgggaa
    17041 tatggtacga tacgttattg aaaaatctgg tcatactgat tgggacggtc gcaagattta
    17101 ccaagaggcc gcaactggta atgctctttg tcaagaagcc attgagcgca tgaaccgcaa
    17161 tctggcgcaa ggcttgctca atattcagta tctgatcgat ccagatgtca tcagtctggg
    17221 tggctctatc agtcaaaatc cagattttat ccaaggtgtc aagaaggctg ttgataactt
    17281 tgtcgatgcc tacgaagaat acacggtcgc accagttatc caggcctgca cctatcacgc
    17341 agatgccaat ctctacggtg cccttgtcaa ctggctacag gaggaaaagc aatggtaaga
    17401 tttataggac ttagtcccaa acaaacgcaa gctattgagg ttttaaaagg tcacatttct
    17461 ctaccagatg tggaagtggc tgtcactcag tctgaccaag cctctatctc tatcgagggt
    17521 gaggaaggtc actatcaatt gacctaccgc aaacctcacc aactttatcg tgccttgtcc
    17581 ttgttggcaa cagttctagc agaagctgat aaagtagaga ttgaggaaca agcagcttac
    17641 gaagatttgg cttacatggt tgactgttct cgaaatgcgg tgctgaatgt cgcttctgcc
    17701 aagcagatga ttgaggtctt ggctctcatg ggctactcaa cctttgagct ttacatggaa
    17761 gacacttacc agattgaagg acagccttac tttggctatt tccgtggagc ttattcagca
    17821 gaggagttgc aggaaatcga agcctatgct caacagtttg acatgacctt tgtaccatgc
    17881 atccagacct tggcccactt gtcggccttt gtcaaatggg gtgtcaagga agtgcaggag
    17941 ctccgtgatg tagaggacat tcttctcatt ggcgaagaaa aggtttatga cctgattgat
    18001 ggcatgtttg ccacgttgtc taaactgaag actcgcaagg tcaatatcgg gatggacgaa
    18061 gcccacttgg ttggtttggg acgctacctg attctgaacg gtgttgtgga tcgtagtctc
    18121 ctcatgtgcc aacacttgga gcgcgtgctg gatattgctg acaaatatgg tttccactgc
    18181 cagatgtgga gtgatatgtt cttcaaactc atgtcagcgg atggccagta cgatcgtgat
    18241 gtggaaattc cagaggaaac tcgtgtctac ctagaccgtc tcaaagaccg tgtgactctg
    18301 gtttactggg attattatca ggatagcgag gaaaaataca accgtaattt ccgcaatcat
    18361 cacaagatta gccatgacct tgcatttgca gggggagctt ggaagtggat tggctttaca
    18421 cctcacaacc attttagccg tctagtggct atcgaggcta ataaagcctg ccgtgccaat
    18481 cagattaaag aagtcatcgt aacgggttgg ggagacaatg gtggtgaaac tgcccagttc
    18541 tctatcctac caagcttgca aatctgggca gaactcagct atcgcaatga cctagatagt
    18601 ttgtctgcgc acttcaagac caatactggt ctaacggttg aagattttat gcagattgac
    18661 cttgccaacc tcttaccaga cctaccaggt aatctcagtg gcatcaatcc caaccgatat
    18721 gtcttttatc aggatgttct ctgtccgata cttgaccgac acatgacacc tgaacaggac
    18781 aagccacact tcgctcaggc ggcgggaact attgctgaca ttaaagaaaa agctggaaac
    18841 tatgcttatc tctttgaaac tcaggcccag ttgaatgcta ttttaagtag caaagtagat
    18901 gtgggacgac gcattcgtca ggcctaccaa gcggatgata aagaaagttt acaacaaatc
    18961 gccagacaag aattaccaga acttagaagc caaattgaag acttccatgc cctctttagt
    19021 caccaatggc tgaaagaaaa caaggtcttt ggtttggata cagttgacat ccgtatgggc
    19081 ggactcttgc aacgcatcaa acgagcagaa agccgtatcg aggtttatct ggctggtcag
    19141 cttgaccgca tcgacgagct ggaagttgaa atcctaccat ttactgactt ctacgcagac
    19201 aaggatttcg cagcaactac agccaaccag tggcatacca ttgcgacagc gtcgacgatt
    19261 tatacgactt aatactcttc gaaaatctct tcaaaccacg tcagcttcca tctgcaacct
    19321 caaaacagtg ttttgagcaa cctgcagcta gcttcctagt ttgctctttg attttcattg
    19381 agtataaaaa caagaacacc ttgcttggcg cagggtgttt cgcgtgaaac agaagaatta
    19441 tctggtttca aatgctacag ttaaaattag taaaacaaga aatagaagct gaaaagccag
    19501 catctgtaga ggcttggatc atttccgtca aattaaaaaa ggttgctacc gacatatata
    19561 gattccaaaa acaaaaacgt tagcggagct agcagatgtg attttatgga gtttcgattt
    19621 tgcaaatgat catgctcatg catttttcat ggataatgtt gagtggagtc atgcagattc
    19681 ttactttctt agctttgtta gtgacgatgt tgaagaacgt tacacagaaa atgtctatct
    19741 ggatagccta agtgtcaaac aaaaatttaa gtttattttc gacttcggtg atgaatggcg
    19801 ttttgaatgc caagtgctga gagaaatcga gacagaggac gaagaagctt atctcgtacg
    19861 ttcggttgga acgtcgccag aacaatatcc agattatgat ggttttgact attaagaatg
    19921 gtaaaattga aatcagtctg tgtaggctta gtatttcaat agacttcctg cgaaaccaaa
    19981 attctagttc atgattgata ataccagcaa tcaaattcat tcgtaatccg aagcgtttac
    20041 gatgatttcg ataggttgtt gaaaacattt taaacgtttt tactttggca aggatgttct
    20101 caaccttgct tctatcctta gatagtgcat ggttacaggc tttatcttca gctgttagcg
    20161 gtttgagttt gctggcttta cgtggagttt gtgcttgagg atatatcttc atgggccctt
    20221 gataatcact gtcagtcaag attttaccag cttgtccgat atttctgcga ctcattttga
    20281 acaacttcat atcatgacaa tagttcacag tgatatccaa agaaacaatt ctcccttgac
    20341 ttgtgacaat cgcttgagcc ttcatagcgt ggcatttctt tttaccagaa tcattcgcta
    20401 attctttttt tagggcgatt gatttatact tccgtcgcat caataatcat taccgtgtcc
    20461 tcagagctga gaggagttct tgaaatcgta acaccacttt gaacaagagt tacttcaacc
    20521 cattggctcc gacggagtaa gttgctttcg tggataccaa aatcagccgc aatttcttca
    20581 taagttcgat attctcgcac atagtgaaga gtggccataa gaaggtcttc taggcttaat
    20641 ttaggttttc gtccaccttt tgcgtgttta agttgataag ctgtttttaa tacagctaac
    20701 atctcttcaa aagtcgtgcg ttgaacacca acaagacatt taaatcgtgc atcggttagt
    20761 tgtttacttg cttcataatt tcgcagggag tctattgact ctttggtagg tgtcaatgtt
    20821 tttttcatct atcccgagaa ttattttctc gccatttgta tttgcaaatg ctgagtaggt
    20881 ttcccagaaa gactctggaa gattgttttt agcttttttg tattctaaat caaccccttc
    20941 aaattttaag tccatatttt tcctttacat ctgttttttg tggttctggt atttgttcaa
    21001 gttgagtgat aatatagcga attgaatttc gagagttttt actcagttaa tttctttttt
    21061 aacccacttt aatttctttt ttaacacggg ttaaaaaaga aattaaagtg ggttaatttt
    21121 ccttgactta aaatttaaaa atgatatact gtgtttatgg agagatgaca atttataaaa
    21181 tgtactactc tattctacta gataatgatt gaataaaact ttttataaca acggctagca
    21241 aagttataat tttatatcta ttagaaaata aatatgtaag gaaatttaaa tgaaaaaaac
    21301 tacaatatta tcattaacta cagctgcggt tattttagca gcatatgtcc ctaatgaacc
    21361 aatcctagca gatactccta gttcggaagt aatcaaagag actaaagttg gaagtattat
    21421 tcaacaaaat aatatcaaat ataaggttct aactgtagaa ggtaacatag gaactgttca
    21481 agtgggtaat ggagttactc ctgtagagtt tgaagctggt caagatggaa aaccattcac
    21541 gattcctaca aaaatcacag taggtgataa agtatttacc gttactgaag tagctagtca
    21601 agcttttagt tattatccag atgaaacagg tagaattgtc tactatccta gctctattac
    21661 tatcccatca agcataaaaa aaatacaaaa aaaaggcttc catggaagta aagctaaaac
    21721 tattattttt gacaaaggca gtcagctgga gaaaattgaa gatagagctt ttgatttttc
    21781 tgaattagaa gagattgaat tgcctgcatc tctagaatat attggaacaa gtgcattttc
    21841 ttttagtcaa aaattgaaaa agctaacctt ttcctcaagt tcaaaattag aattaatatc
    21901 acatgaggct tttgctaatt tatcaaattt agagaaacta acattaccaa aatcggttaa
    21961 aacattagga agtaatctat ttagactcac tactagctta aaacatgttg atgttgaaga
    22021 aggaaatgaa tcgtttgcct cagttgatgg tgttttgttt tcaaaagata aaactcaatt
    22081 aatttattat ccaagtcaaa aaaatgacga aagttataaa acgcctaagg agacaaaaga
    22141 acttgcatca tattcgttta ataaaaattc ttacttgaaa aaactcgaat tgaatgaagg
    22201 tttagaaaaa atcggtactt ttgcatttgc ggatgcgatt aaacttgaag aaattagctt
    22261 accaaatagt ttagaaacta ttgaacgttt agccttttac ggtaatttag aattaaaaga
    22321 acttatatta ccagataatg ttaaaaattt tggtaaacac gttatgaacg gtttaccaaa
    22381 attaaaaagt ttaacaattg gtaataatat caactcattg ccgtccttct tcctaagtgg
    22441 cgtcttagat tcattaaagg aaattcatat taagaataaa agtacagagt tttctgtgaa
    22501 aaaagataca tttgcaattc ctgaaactgt taagttctat gtaacatcag aacatataaa
    22561 agatgttctt aaatcaaatt tatctactag taatgatatc attgttgaaa aagtagataa
    22621 tataaaacaa gaaactgatg tagctaaacc taaaaagaat tctaatcagg gagtagttgg
    22681 ttgggttaaa gacaaaggtt tatggtatta cttaaa
//
LOCUS       DBEJAU010000035        22053 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC323 isolate 683620
            SAMN38261939-rid24807223.denovo.035, whole genome shotgun sequence.
ACCESSION   DBEJAU010000035 DBEJAU010000000
VERSION     DBEJAU010000035.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261939
            Sequence Read Archive: SRR26833919
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 22053)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 22053)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576303.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576303.1
            Genome Coverage       :: 154x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/19/2025 01:05:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,121
            CDSs (total)                      :: 2,078
            Genes (coding)                    :: 1,943
            CDSs (with protein)               :: 1,943
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 36
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 72 of 135
            Pseudo Genes (incomplete)         :: 63 of 135
            Pseudo Genes (internal stop)      :: 51 of 135
            Pseudo Genes (multiple problems)  :: 46 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..22053
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261939-rid24807223.denovo.035"
                     /strain="GPSC323"
                     /isolate="683620"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            complement(58..1077)
                     /gene="adhP"
                     /locus_tag="ACL29Z_001407"
     CDS             complement(58..1077)
                     /gene="adhP"
                     /locus_tag="ACL29Z_001407"
                     /EC_number="1.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000649145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alcohol dehydrogenase AdhP"
                     /protein_id="HGR0069701.1"
                     /translation="MKAVVVNPESTGVAIEEKVLRPLETGEALVEVEYCGVCHTDLHV
                     AHGDFGQVPGRVLGHEGIGIVKEIAPDVKSLKVGDRVSVAWFFEGCGTCEYCTTGRET
                     LCRTVKNAGYSVDGGMAEQCIVTADYAVKVPDGLDPAQASSITCAGVTTYKAIKEAKV
                     EPGQWVVLYGAGGLGNLAVQYAKKVFNAHVIAVDINNDKLALAKEVGADIVINGLEVE
                     DVAGLIKEKTDGGAHSAVVTAVSKVAFNQAVDSVRAGGRVVAVGLPSEMMELSIVKTV
                     LDGIQVIGSLVGTRKDLEEAFQFGAEGLVAPVVQKRPVEDAVAIFDEMEKGQIQGRMV
                     LDFTH"
     gene            complement(1417..2229)
                     /locus_tag="ACL29Z_001408"
     CDS             complement(1417..2229)
                     /locus_tag="ACL29Z_001408"
                     /EC_number="3.1.3.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000162344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HGR0069702.1"
                     /translation="MTKKIIAVDLDGTLLNSDSQISDFTKKTIKKVAEKGHQVIITTG
                     RPYRMSKDFYRELGLDTPMINFNGSLTHLPDQVWDFEKCLTVDKKYLLDMVQRSEDIQ
                     ADFIAGEYRKKFYITNPNEEIANPKLFGVEAFQPEDQFQPELVTKDPNCILLQTRASD
                     KYALAKDMNAFYQHQLSINTWGGPLNILECTPKGVNKAFALDYLLKIMNRDKKDLIAF
                     GDEHNDTEMLAFAGKGYAMKNANPELLPYADEQISLTNDQDGVAKTLQDLFL"
     gene            2419..3837
                     /locus_tag="ACL29Z_001409"
     CDS             2419..3837
                     /locus_tag="ACL29Z_001409"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000359314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0015205 - nucleobase transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NCS2 family permease"
                     /protein_id="HGR0069703.1"
                     /translation="MDKLFKLKENGTDVRTEVLAGLTTFFAMSYILFVNPQILSQTGM
                     PAQGVFLATIIGAVAGTLMMTFYANLPYAQAPGMGLNAFFTFTVVFGLGYSWQEALAM
                     VFICGIISLIITLTNVRKMIIESIPNALRSAISAGIGVFLAYVGIKNAGLLKFTIDPG
                     NYTVVGEGADKAQATIAANSSAVPGLVSFNNPAVLVALAGLAITIFFVIKGIKGGIIL
                     SILTTTVLAISVGLVDLSSIDFANNHVGAAFEDLKTIFGAALGSEGLGALVSDTARLP
                     ETLMAILAFSLTDIFDTIGTLIGTGEKVGIVATNGENHQSAKLDKALYSDLIGTTVGA
                     IAGTSNVTTYVESAAGIGAGGRTGLTALVVAICFAISSFFSPLLAIVPTAATAPILII
                     VGIMMLGSLKNIHWDDMSEAVPAFFTSIFMGFSYSITQGIAVGFLTYTLTKLVKGQVK
                     DVHAMIWILDALFILNYISMAL"
     gene            3890..4597
                     /locus_tag="ACL29Z_001410"
     CDS             3890..4597
                     /locus_tag="ACL29Z_001410"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260476.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysostaphin resistance A-like protein"
                     /protein_id="HGR0069704.1"
                     /translation="MKEKNMWKELLNRAGWILVFLLAVLLYQVPLVVTSILTLKEVAL
                     LQSGLIVAGLSIVVLALFIMGARKTKLASFNFSFFRAKDLARLGLSYLVIVGSNILGS
                     ILLQLSNETTTANQSQINDMVQNSSLISSFFLLALLAPICEEILCRGLVPKKIFRGKE
                     NLGFVVGTIVFALLHQPSNLPSLLIYGGMSTVLSWTAYKTQRLEMSILLHMIVNGIAF
                     CLLALVVIMSRTLGISV"
     gene            4692..5666
                     /gene="folP"
                     /locus_tag="ACL29Z_001411"
     CDS             4692..5666
                     /gene="folP"
                     /locus_tag="ACL29Z_001411"
                     /EC_number="2.5.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004156 - dihydropteroate synthase
                     activity [Evidence IEA];
                     GO_process: GO:0009396 - folic acid-containing compound
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydropteroate synthase"
                     /protein_id="HGR0069705.1"
                     /translation="MMKILEGVTDMSSKANHAKTVICGIINVTPDSFSDGGQFFALEQ
                     ALQQARKLIAEGASMLDIGGESTRPGSSYVEIEEEIQRVVPVIKAIRKESDVLISIDT
                     WKSQVAEAALAAGADLVNDITGLMGDEKMAHVVAEARAQVVIMFNPVMARPQHPSSLI
                     FPHFGFGQAFTEEELADFETLPIEDLMVAFFERALARAAEAGIAPENILLDPGIGFGL
                     TKKENLLLLRNLDKLHQKGYPIFLGVSRKRFVINILEENGFEVNPETELGFRNRDTAS
                     AHVTSIAARQGVEVVRVHDVASHRMAVEIASAIRLADEAENLDLKQYK"
     gene            5668..6990
                     /locus_tag="ACL29Z_001412"
     CDS             5668..6990
                     /locus_tag="ACL29Z_001412"
                     /EC_number="6.3.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000658404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004326 - tetrahydrofolylpolyglutamate
                     synthase activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008841 - dihydrofolate synthase activity
                     [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0006730 - one-carbon metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="folylpolyglutamate synthase/dihydrofolate
                     synthase family protein"
                     /protein_id="HGR0069706.1"
                     /translation="MKEIENNQWIANYRTDQPHFGLERMVELLALRGNPHLKLKVLHI
                     GGTNGKGSTIAFLKKMLEKLGLRVGVFNSPYLIHYTDQISINGESISEARLEALMADY
                     QSLMGGEAVANLQGTTEFEIITALAYDYFASEQVDVAIMEVGMGGLLDSTNVCQPILT
                     GITTIGLDHVALLGDTLEAIAEQKAGIIKQGMPLVTGRIAPEALAVIDRIAEGKDAPR
                     LAYGTDYQVRHQESVVTGEVFDYTSAVRQGRFQTSLLGLYQIENAGMAIALLDTFCQE
                     DGRELASNDFLGQALEEISWPGRLEIVSRDPLMILDGAHNPHAIKALLVTLQERFADY
                     HKEILFTCIKTKALEDMLDLLGAMPDTELTLTHFADSRATDESVLKEAAKSRNLSYQD
                     WHDFLEQNLTDKKEEKQTVRIVTGSLYFLSQVRAYLMERKNENGYTKD"
     gene            6971..7525
                     /gene="folE"
                     /locus_tag="ACL29Z_001413"
     CDS             6971..7525
                     /gene="folE"
                     /locus_tag="ACL29Z_001413"
                     /EC_number="3.5.4.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006155259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003934 - GTP cyclohydrolase I activity
                     [Evidence IEA];
                     GO_process: GO:0046654 - tetrahydrofolate biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GTP cyclohydrolase I FolE"
                     /protein_id="HGR0069707.1"
                     /translation="MDTQKIEAAVKMIIEAVGENANREGLQETPARVARMYQEIFSGL
                     GQTAEEHLSKSFEIIDDNMVVEKDIFFHTMCEHHFLPFYGRAHIAYIPDGRVAGLSKL
                     ARTVEVYSKKPQIQERLNIEVADALMDYLGAKGAFVVIEAEHMCMSMRGVRKPGTATL
                     TTVARGLFETDKDLRDQAYRLMGL"
     gene            7568..8380
                     /gene="folK"
                     /locus_tag="ACL29Z_001414"
     CDS             7568..8380
                     /gene="folK"
                     /locus_tag="ACL29Z_001414"
                     /EC_number="2.7.6.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397195.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003848 -
                     2-amino-4-hydroxy-6-hydroxymethyldihydropteridine
                     diphosphokinase activity [Evidence IEA];
                     GO_process: GO:0009396 - folic acid-containing compound
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="2-amino-4-hydroxy-6-
                     hydroxymethyldihydropteridine diphosphokinase"
                     /protein_id="HGR0069708.1"
                     /translation="MDQLQIKDLEMFAYHGLFPSEKELGQKFVVSAILSYDMTKAATD
                     LDLTASVHYGELCQQWTTWFQETSEDLIETVAYKLVERTFESYPLVQEMKLELKKPWA
                     PVHLSLDTCSVTIHRRKQRAFIALGSNMGDKQVNLKQAIDKLRARGIHILKESSVLAT
                     EPWGGVEQDSFANQVVEVETWLPAQDLLETLLAIESELGRVREVHWGPRLIDLDLLFV
                     EDQILYTDDLILPHPYIAERLFVLESLQEIAPHFIHPILKQPIRNLYDALKK"
     gene            complement(8425..8742)
                     /locus_tag="ACL29Z_001415"
     CDS             complement(8425..8742)
                     /locus_tag="ACL29Z_001415"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000886024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF960 domain-containing protein"
                     /protein_id="HGR0069709.1"
                     /translation="MAFTNTHMRSASFGIVTSLPDDIIDSFWYIIDHFLKNVFELEEE
                     LEFQLLNNQGKITFHFSSQHLPTAIDFDFNHPFDPRYPPRVLVLDMDGRETILLPEEN
                     DLF"
     gene            9099..9545
                     /gene="rplM"
                     /locus_tag="ACL29Z_001416"
     CDS             9099..9545
                     /gene="rplM"
                     /locus_tag="ACL29Z_001416"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003083327.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L13"
                     /protein_id="HGR0069710.1"
                     /translation="MNKTTFMAKPGQVERKWYVVDATDVPLGRLSAVVASVLRGKNKP
                     TFTPHTDTGDFVIVINAEKVKLTGKKATDKIYYTHSNHPGGLKQISAGELRSKNAVRL
                     IEKSVKGMLPHNTLGRAQGMKLKVFVGAEHTHAAQQPEVLDISGLI"
     gene            9565..9957
                     /gene="rpsI"
                     /locus_tag="ACL29Z_001417"
     CDS             9565..9957
                     /gene="rpsI"
                     /locus_tag="ACL29Z_001417"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002942223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S9"
                     /protein_id="HGR0069711.1"
                     /translation="MSQAQYAGTGRRKNAVARVRLVPGTGKITVNKKDVEEYIPHADL
                     RLVINQPFAVTSTVGSYDVFVNVVGGGYAGQSGAIRHGIARALLQVDPDFRDSLKRAG
                     LLTRDSRKVERKKPGLKKARKASQFSKR"
     gene            complement(10219..10641)
                     /locus_tag="ACL29Z_001418"
     CDS             complement(10219..10641)
                     /locus_tag="ACL29Z_001418"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001211071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA];
                     GO_process: GO:0015074 - DNA integration [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HGR0069712.1"
                     /translation="MRFIVETFPIFSISNDLLQLLTSWKKQQKYELAKFGIISNPEQF
                     IFTYIDTKGNINKPLHSDYLNNKMKTIRKRHPELTHATPHKLRHTGATLAKQAGMSLE
                     AISEALIHSDTGTTQIYVNTSNVVPMAVGEFALQSLKQ"
     gene            10788..10964
                     /locus_tag="ACL29Z_001419"
     CDS             10788..10964
                     /locus_tag="ACL29Z_001419"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003017298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0069713.1"
                     /translation="MSLDIDKEKMTIMGIAFENRSVFRSVWYALSTNMIEGWRPTVSD
                     VEKLRDEALALVWG"
     gene            11371..13584
                     /locus_tag="ACL29Z_001420"
     CDS             11371..13584
                     /locus_tag="ACL29Z_001420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000688702.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004553 - hydrolase activity, hydrolyzing
                     O-glycosyl compounds [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TIM-barrel domain-containing protein"
                     /protein_id="HGR0069714.1"
                     /translation="MKIFKGEFYRISVLTDKLVRLEYSQTGSFEDRTTQLIYNRDFGQ
                     ISLDYIETSNVLDIMTDYFHLHFNKGEFNAENLFIELKGNFAVYGSRWYFGESIETLK
                     GTARTLDKADGAISLEDGIISRNGIALLDDSQGFIWDEQSGYIERENQIDLYFFAYGH
                     DYRGAIRDFYHLTGSTPLLPRYALGNWWSRYWPYTSDEYLDLIDRFETEKIPLSIGVL
                     DMDWHITDIPARFGSGWTGYSWNRNLIPNPEQLLQQLHDRKLKLSLNVHPADGIRAYE
                     EAYPQIAKRLGLNVELEEPAIFDFFNPSFREAYFKDVHYELEKQGVDFWWIDWQQGTQ
                     GMLDPLWLLNHYHYQDSCKNAEGGLILSRYAGPGSHRYPVGFSGDTIISWNSLRFQPY
                     FTATASNIGYSWWSHDIGGHMLGDYDEELQTRWLQFGVFSPITRLHSSRSPFNSKEPW
                     FFSETTSKIMKKYLRLRHQMISYLYTMNVKTHEEGAPLISPIYYFYPENDESYNVPNQ
                     YFFGTELMVAPIVEKMDLTFQSAKVDVWFPEGEWYDFFSEKKYTGGVKLSVYRDISTT
                     PVFAKSGAIIPLVGSEIGMGVDLPEVVDWYVFPGKQHSFEMIEDQNGQRYKTRLSIDW
                     EMGMVELALQGDSSIVPSNRKHRIHFKGTNVSIIELPNKNDTAKFEWKDNKRTSLNDE
                     VFRLLKTASLPYELKDRLLNQFINAKNSHDLMNILHHQDKELRGRLLEMIFTSQN"
     gene            complement(13806..14282)
                     /locus_tag="ACL29Z_001421"
     CDS             complement(13806..14282)
                     /locus_tag="ACL29Z_001421"
                     /EC_number="1.11.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398949.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004602 - glutathione peroxidase activity
                     [Evidence IEA];
                     GO_function: GO:0043295 - glutathione binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione peroxidase"
                     /protein_id="HGR0069715.1"
                     /translation="MTSLYDFSVLNQNNQATPLDSYRGKVLLIVNTATGCGLTPQYQG
                     LQELYERYQDQGFEILDFPCNQFMGQAPGSAEEINAFCSLHFQTTFPRFAKIKVNGKE
                     ADPLYVWLKDQKSGPLGKRIEWNFAKFLIGRDGQVFERFSSKTDPKQIEEAIQTLL"
     gene            14505..17708
                     /locus_tag="ACL29Z_001422"
     CDS             14505..17708
                     /locus_tag="ACL29Z_001422"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001193686.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG-anchored hyaluronate lyase"
                     /protein_id="HGR0069716.1"
                     /translation="MQTKTKKLIVSLSSLVLSGFLLNHYMTVGAEETTTNTIQQSQKE
                     VQYQQRDTKNLVENGDFGQTEDGSSPWTGSKAQGWSAWVDQKNSSADASTRVIEAKDG
                     AITISSPEKLRAAVHRMVPIEAKKKYKLRFKIKTDHKVGIAKVRIIEESDKDKRLWNS
                     ATTSGTKDWQTIEADYSPTLDVDKIKLELFYETGTGTVSFKDIELVEVADQPSEDSQT
                     DKQLEEKIDLPIGKKHVFSLADYTYKVENPDVASVKNGILEPLKEGTTNVIVSKDGKE
                     VKKIPLKILASVKDAYTDRLDDWNGIIAGNQYYDSKNEQMAKLNQELEGKVADSLSSI
                     SSQADRIYLWEKFSNYKTSANLTATYRKLEEMAKQVTNPSSRYYKDETVVRTVRDSME
                     WMHKHVYNSEKSIVGNWWDYEIGTPRAINNTLSLMKEYFSDEEIKKYTDVIEKFVPDP
                     EHFRKTTDNPFKALGGNLVDMGRVKVIAGLLRKDDQEISSTIRSIEQVFKLVDQGEGF
                     YQDGSYIDHTNVAYTGAYGNVLIDGLSQLLPVIQKTKNPSDKDKMQTMYHWIDKSFAP
                     LLVNGELMDMSRGRSISRANSEGHVAAVEVLRGIHRIADMSEGETKQRLQSLVKTIVQ
                     SDSYYDVFKNLKTYKDISLMQSLLSDAGVASVPRTSYLSAFNKMDKTAMYNAEKGFGF
                     GLSLFSSRTLNYEHMNKENKRGWYTSDGMFYLYNGDLSHYSDGYWPTVNPYKMPGTTE
                     TDAKRADSDTGKVLPSAFVGTSKLDDANATATMDFTNWNQTLTAHKSWFMLKDKIAFL
                     GSNIQNTSTDTAATTIDQRKLESSNSYKVYVNDKEASLTEQEKDYPETQSVFLESSDS
                     KKNIGYFFFKKSSISMSKALQKGAWKDINEGQSDKEVENEFLTISQAHKQNGDSHGYM
                     LIPNVDRATFNQMIKELESSLIENNETLQSVYDAKQGVWGIVKYDDSVSTISNQFQVL
                     KRGVYTIRKEGDEYKIAYYNPETQESAPDQEVFKKLEQAAQPQVQNSKEKEKSEEEKN
                     HSDQKNLPQTGEGQSILASLGFLLLGAFYLFRRGKNN"
     gene            18088..18464
                     /gene="tnpA"
                     /locus_tag="ACL29Z_001423"
                     /pseudo
     CDS             18088..18464
                     /gene="tnpA"
                     /locus_tag="ACL29Z_001423"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011148688.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS200/IS605 family transposase"
     gene            18646..18708
                     /locus_tag="ACL29Z_001424"
                     /pseudo
     CDS             18646..18708
                     /locus_tag="ACL29Z_001424"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006596946.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS200/IS605 family transposase"
     gene            complement(18852..19481)
                     /locus_tag="ACL29Z_001425"
     CDS             complement(18852..19481)
                     /locus_tag="ACL29Z_001425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000167291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional 4-hydroxy-2-oxoglutarate
                     aldolase/2-dehydro-3-deoxy-phosphogluconate aldolase"
                     /protein_id="HGR0069717.1"
                     /translation="MTKSDTIIELKKQKIVAVIRGNTKEEGLQASIACIKGGIKAIEI
                     AYTNQYAGQIIKELVDLYQDDQSVCIGAGTVLDAVTARDAILAGANYVVSPSFHAETA
                     KMCNLYSTPYIPGCITLTEITTALEAGSEIIKLFPGSTLSPAYISAVKAPIPQVSVMV
                     TGGVGLNNIPQWFAAGADAVGIGGELNKLASQGNFDRISEIAQQYVTLR"
     gene            complement(19491..20492)
                     /locus_tag="ACL29Z_001426"
     CDS             complement(19491..20492)
                     /locus_tag="ACL29Z_001426"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730651.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005829 - cytosol [Evidence IEA];
                     GO_function: GO:0019200 - carbohydrate kinase activity
                     [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sugar kinase"
                     /protein_id="HGR0069718.1"
                     /translation="MTKILLFGEPLIRISPLDATSIGDHVASSTYFGGSEINIACNLQ
                     ALGISTKVFTALPANEIGDRFLTFLKQHQIDTSSICRLGDRIGLYYLENGFGCRQSEV
                     FYDRKHTSISQIRPNMLDMDSLFQGISHFHFSGITVAIGQEVRAILLLLLEEAKRRGI
                     VVSMDLNLRTKMISVLEAKYEFSKFARFTDYCFGIDPLMIDDQNLEMFPRDSASLEEV
                     ENRMRLLKEAYGFKAIFHTLRSSDEQDKNVYQAYALEERFEESVQLKTAVYQRIGSGD
                     AFISGALYQLLHHSSLKTTIDFAVASATLKCTLPGDHLSTSATSIENLLANAQDIIR"
     gene            complement(20523..21164)
                     /locus_tag="ACL29Z_001427"
     CDS             complement(20523..21164)
                     /locus_tag="ACL29Z_001427"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RpiB/LacA/LacB family sugar-phosphate isomerase"
                     /protein_id="HGR0069719.1"
                     /translation="MKIALINENSQASKNHIIYDSLKEATDKKDYQLFNYGMRGEEGE
                     SQLTYVQNGLMAAILLNTKAVDFVVTGCGTGVGAMLALNSFPGVVCGLAVDPTDAYLY
                     SQINGGNALSIPYAKGFGWGAELTLKLMFERLFAEEMGGGYPRERVIPEQRNARILNE
                     VKQITHNDLMTILKTIDQDFLKDTISGKYFQEYFFENCQDDEVAAYLKEVLAK"
     gene            complement(21183..21998)
                     /locus_tag="ACL29Z_001428"
     CDS             complement(21183..21998)
                     /locus_tag="ACL29Z_001428"
                     /EC_number="1.1.1.69"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000185867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="gluconate 5-dehydrogenase"
                     /protein_id="HGR0069720.1"
                     /translation="MTNTSFSIEQFSLKGKIALITGASYGIGFAIAKSYAEAGATIVF
                     NDINQDLVNKGIEAYREVGIEAHGYVCDVTDEDGIQAMVKQIEQEVGVIDILVNNAGI
                     IRRVPMCEMSAADFRKVIDIDLNAPFIVSKAVIPSMIKKGHGKIINICSMMSELGRET
                     VSAYAAAKGGLKMLTRNIASEYGGANIQCNGIGPGYIATPQTAPLRELQEDGSRHPFD
                     QFIIAKTPAARWGNPEDLMGPAVFLASDASNFVNGHILYVDGGILAYIGKQPE"
BASE COUNT         6625 a         4044 c         4858 g         6526 t
ORIGIN      
        1 atttaatata aaaaagttag aagaagcttc caacttttaa aataggtttc tattagatta
       61 gtgggtgaag tcgagtacca tacgtccttg gatttgacct ttttccattt cgtcgaaaat
      121 ggcaacagca tcttctactg gacgtttttg aacaactggg gctaccagac cttctgcacc
      181 aaattggaag gcttcttcta agtctttacg agttccgaca agagaaccga tgacttggat
      241 tccatcgagg actgttttaa cgatactgag ttccatcatt tcagaaggaa gaccaacagc
      301 gacgacgcga ccaccagcac gaacggagtc aacagcctgg ttgaaggcaa ctttagacac
      361 agcagttacg acagctgaat gagctcctcc atcagttttt tctttaatga gtccagctac
      421 atcttcaact tcgaggccgt taatcacaat gtcagcgcct acttcttttg caagggcaag
      481 tttgtcattg ttgatatcga ctgcgataac atgagcattg aatacttttt tagcgtattg
      541 aacagcgagg ttaccaagtc caccagcacc gtaaagaaca acccattggc ctggttcaac
      601 ttttgcttct ttgatagctt tataggttgt tactccagca catgtgatag aagaagcttg
      661 ggctggatca agtccgtcag gaactttgac agcatagtca gcagttacga tacattgttc
      721 agccatacca ccgtctactg agtagccagc atttttcact gtacggcaaa gggtttcgcg
      781 accagttgta cagtattcgc aagtgccaca tccttcaaag aaccaagcaa cgctgacgcg
      841 gtcaccgact ttaaggcttt tcacatctgg agcaatctct ttaacgatac cgataccttc
      901 gtgcccaaga acacgtcctg ggacttgacc aaagtcacca tgagcaacgt ggaggtcggt
      961 gtggcaaacg ccacagtatt caacttctac aagtgcttcc ccagtttcaa gtggacggag
     1021 tactttttct tcaatagcaa caccagtgct ttctggattt acaacaacag ctttcatagc
     1081 tatcctcctt gatattgacc gagaacaggg acaacgggac tggattgatt ttttgtcaac
     1141 agagtcgagt gtgacgagct ctcttgtatt tatatgtgaa gtatatcaca aaagaaagcc
     1201 ttttccaagg ttttggagac aaaaagtaga acaatcgatt aactggttga tgagactgtg
     1261 aaaagagcac aaagaccagc ttgcaagctg gtcatactct tcgaaaatct cttcaaacca
     1321 cgtcagcttc atcttacaac ctcaaagcag tgctttgagc aacctacggc tagcttccta
     1381 gtttgctctt tgattctcat tgagtatcag tataggttat aagaataagt cttgtagggt
     1441 tttggcaacc ccatcttggt cgttggtaag ggaaatttgc tcatctgcat aagggagtag
     1501 ctctggattg gcatttttca tggcataacc cttcccagca aaagcgagca tttcggtatc
     1561 attgtgttca tccccaaagg caatcaaatc ttttttgtca cgattcatta tcttgagcaa
     1621 gtagtccaaa gcaaaggcct tgttgacacc ttttggggta cattcaagga tattgagcgg
     1681 acctccccag gtattgatag aaagttgatg ctggtagaag gcgttcatgt cttttgccaa
     1741 ggcatatttg tcactggctc tggtctgcaa gaggatacag ttagggtcct tggtcaccaa
     1801 ttcaggctgg aattgatctt caggctggaa agcttctaca ccaaatagtt tgggattggc
     1861 aatttcttca ttgggatttg taatgtagaa ttttttgcga tattctccag cgataaaatc
     1921 ggcttgaatg tcctctgaac gttgaaccat atctagcaga tattttttgt ctacagtcaa
     1981 acacttttca aaatcccaaa cttggtctgg taaatgagta agggatccgt tgaagttaat
     2041 cataggagtg tctaagccca gttcacggta aaaatctttt gacatacggt aagggcgacc
     2101 tgtcgtaata ataacctgat ggcctttttc agcaactttt ttgatggttt ttttggtaaa
     2161 gtcagaaatt tgactgtctg agttgagcag ggttccatcc aggtcaactg caataatttt
     2221 tttcgtcata tggacctttc tagtgtgttt tcagataaga tgtcttctat tataacagaa
     2281 agcaggcaga aaagcagatt ccaaacaaaa aatgaaattg gattaatttc ttaaacaaat
     2341 caaacaaaga cattgaaaaa gtgaatgata aatgatataa ttctattatt gttcgtaaaa
     2401 attaaaagga gattgatgat ggacaaatta tttaaactaa aagagaacgg tacagacgtt
     2461 cgtacagagg ttctcgctgg tttaacaact ttctttgcaa tgagctatat tctctttgta
     2521 aacccacaaa tactttcaca aacaggaatg cctgctcagg gcgtcttcct agcgacgatt
     2581 attggtgcag tagcgggtac cttgatgatg actttttatg ctaacttacc ttatgcccaa
     2641 gcgccaggta tgggactcaa tgccttcttt acctttacag ttgtattcgg gcttggttat
     2701 tcttggcaag aagccctagc tatggtcttc atctgtggga ttatttcatt gattattacc
     2761 ttgacaaatg ttcgtaaaat gatcattgaa tcgattccca atgctcttcg ctcagctatt
     2821 tcagctggta tcggtgtctt cctggcctat gtagggatta agaatgctgg acttttgaaa
     2881 ttcacgattg atccaggcaa ctatactgtt gtaggagaag gggctgacaa agctcaagca
     2941 acgattgcag caaactcttc agcagttcca ggattggtca gctttaataa tccagctgtt
     3001 ttagtggctc ttgcaggact tgccattact atcttctttg tcatcaaagg gattaaaggg
     3061 ggaattattc tctctatctt gacaacaact gttcttgcta tttcagttgg tttggttgat
     3121 ttgtctagta tcgattttgc taataaccat gttggtgcag cttttgaaga tttgaagaca
     3181 atctttggtg cagctcttgg ttcagaagga ttgggagctt tggtttcaga tacagctcgc
     3241 ttgcctgaaa ctctgatggc cattcttgcc ttctcattga cagatatttt tgacacaatt
     3301 ggtaccttga tcggtacagg tgaaaaagtt ggtattgtag cgacaaatgg tgaaaatcac
     3361 caatcagcca aattggataa ggctctttac tctgatttga ttggaacgac agtcggtgcc
     3421 attgcaggta cttcaaacgt aacgacttat gttgagtctg ctgctggtat cggtgcaggt
     3481 ggacgtactg gtttgacagc cttggttgta gctatctgtt ttgcgatttc aagcttcttt
     3541 agcccacttc tagcgatcgt accaacagcg gctacagctc caatcttgat tatcgttggg
     3601 attatgatgc ttggtagctt gaaaaatatc cattgggatg atatgtctga agcagttcct
     3661 gccttcttca catctatctt tatgggattc agctactcta tcactcaagg gattgcagtt
     3721 ggtttcttga cttacacttt gactaagctt gtcaaaggtc aagttaaaga tgttcatgcc
     3781 atgatttgga ttttggatgc cttgtttatc cttaactaca tcagcatggc cttataatag
     3841 aatgacccag ggggatttcc cccctttttt aatacaaagg agataggtga tgaaagagaa
     3901 aaatatgtgg aaagaattgt tgaatcgtgc aggctggatt ttggtctttt tacttgccgt
     3961 ccttttatat caggttcccc tagtggttac ctctattttg actttaaaag aagtagccct
     4021 gctacagtca gggctgatag ttgctggcct ttcaattgtg gttctggctc tatttattat
     4081 gggagctcgt aaaaccaagt tagctagttt taatttttct ttttttagag ctaaagattt
     4141 ggcacgtttg ggcttgagtt atttagttat tgtcgggtca aatatacttg gttctatctt
     4201 gttgcaactg tcaaatgaga cgacaacagc taaccagtct cagattaacg atatggttca
     4261 aaatagttcg ttgatttcca gtttcttctt gctagccttg cttgctccga tttgtgagga
     4321 aatcttgtgc cgtgggcttg ttcctaaaaa gattttccga ggcaaggaga acttgggatt
     4381 tgtagtcggt acgattgtgt ttgctttatt gcatcaacca agtaatttac cttctttatt
     4441 gatttatgga ggtatgtcga cagttctatc ttggacggcc tacaagaccc aacgtttgga
     4501 aatgtcgatc ttgcttcaca tgattgttaa tgggattgct ttctgtttgt tggctcttgt
     4561 ggtgattatg agtcggacat taggaatttc tgtttaaaag tttttatgta ggaaccgacc
     4621 tctttctact agggaaagat gaatgcaatc gtgtccatct ttttcttttt atggtaaaat
     4681 agaaaaataa tatgatgaaa atccttgagg gagtgaccga tatgtcaagt aaagccaatc
     4741 atgcaaagac agttatttgc ggaattatca atgtaacccc agactccttt tcggacggtg
     4801 gtcaattttt tgctcttgag caggcgctcc agcaggctcg taaattgata gcagaaggag
     4861 ccagtatgct agatatcggc ggagaatcga ctcggccggg aagtagctat gttgagatag
     4921 aagaggaaat ccagcgtgtt gttccagtga tcaaagcgat tcgcaaggaa agtgatgtcc
     4981 tcatctctat tgatacttgg aagagtcaag tagcagaggc tgctttggct gcgggtgccg
     5041 atctagtcaa tgatatcact ggtcttatgg gtgatgagaa aatggctcat gtggtagctg
     5101 aagcgagagc gcaagtggtc atcatgttta atccagttat ggcgcgacct cagcacccta
     5161 gctcgctcat cttccctcat tttggttttg gtcaagcttt tacagaggaa gagttagctg
     5221 actttgaaac attgccaatc gaagacttga tggtggcttt ctttgaacga gcactagcga
     5281 gagcggcaga agctggtatt gcaccagaaa atatcctgtt ggatccagga attggctttg
     5341 gtctgaccaa gaaagaaaat ctgcttcttt tacggaacct ggataaacta catcagaaag
     5401 gctatccaat ctttctcgga gtttcgcgca agcgatttgt catcaatatc ctagaggaga
     5461 atggttttga agtcaatcct gagacagagc ttggtttccg aaatcgggac acggcttcgg
     5521 ctcatgtaac tagtatcgct gcgagacagg gtgtagaagt ggtgcgcgtg catgacgtag
     5581 ctagtcacag gatggcagtt gaaattgcct ctgccattcg tctggctgat gaagcggaaa
     5641 atttagattt aaaacaatat aaataagatg aaagaaattg aaaacaatca gtggattgct
     5701 aactaccgga cggatcaacc gcattttggt ttggaacgaa tggtggaact gttagctttg
     5761 cgtggcaatc cccatctcaa actcaaggtc ctccatatcg gagggactaa cggcaagggc
     5821 tcgactattg cttttttgaa aaagatgcta gaaaagctag ggctgagagt tggcgtgttt
     5881 aactcgccct atctcattca ttacacagac cagattagca tcaatgggga atcgatctca
     5941 gaagcgaggc tagaagctct catggcagac tatcagtctt tgatgggggg agaagcggtc
     6001 gccaatttac agggcacaac cgagtttgag attatcacag ccctggccta tgactacttt
     6061 gcctcagagc aagtagatgt ggccatcatg gaagttggca tgggtggact tttggatagt
     6121 accaatgtct gtcagcccat tttgacagga attacaacta ttggcttgga tcatgtggcc
     6181 ctacttggtg acaccttgga ggccatagca gagcagaagg caggtattat caaacaaggg
     6241 atgcccttgg taacagggcg tattgctcca gaagccttgg ctgtgattga ccgcattgcg
     6301 gaagggaaag atgcgccgag acttgcctac gggacagatt atcaggttcg tcatcaagaa
     6361 agtgtggtga caggggaagt ctttgactat acaagtgctg tcagacaagg tcgcttccag
     6421 actagcctgc ttggtttgta ccaaatagag aatgctggga tggccatagc tttacttgat
     6481 actttttgtc aagaagatgg tcgagagcta gcaagcaatg actttcttgg tcaagccttg
     6541 gaagaaataa gttggccagg gcgtttggaa atcgtgtcaa gagatccctt gatgattttg
     6601 gatggagccc ataatcccca tgctatcaag gccttgttgg taaccttgca agaacgtttt
     6661 gcggattatc ataaggaaat cctcttcact tgtatcaaaa ccaaagcctt ggaggatatg
     6721 ttggacttgc tgggagccat gccagatacc gagcttactc taacacattt tgcggatagt
     6781 cgggcgacgg atgaaagcgt gctgaaagag gcagctaagt ctagaaatct cagctaccaa
     6841 gattggcatg attttctaga gcagaatttg acagataaaa aagaagagaa acaaacagtt
     6901 aggattgtca caggttcctt gtatttcttg agccaagtga gggcctatct gatggagagg
     6961 aagaacgaga atggatacac aaaagattga agcagctgta aaaatgatta tcgaggctgt
     7021 aggagagaac gctaatcgcg agggcttgca ggaaacacct gctcgtgtag cccgtatgta
     7081 tcaagagatt ttttcaggtc ttggtcaaac agcagaggaa catttgtcaa aatcctttga
     7141 aattattgac gataatatgg tggtagaaaa ggatatcttt ttccatacca tgtgtgaaca
     7201 ccacttcttg ccattttatg gtagagcgca cattgcctac attccagatg gtcgtgtggc
     7261 aggcttgtct aagctagccc gtacggttga agtttattcg aaaaaaccac aaattcaaga
     7321 acgtttgaat atcgaagtgg ccgatgcctt gatggactat ctaggtgcta aaggagcctt
     7381 tgttgtcatt gaggcggaac atatgtgtat gagtatgcgt ggtgttagaa aaccaggcac
     7441 tgcaaccttg acgacagtag ctcgtggtct atttgaaaca gataaggacc tccgcgacca
     7501 agcttatcgt ttaatggggc tataaaaaga atccgtttca agcggatttt tctagaaagg
     7561 aatcattatg gatcaactgc agattaagga tttggaaatg tttgcctatc atggtctttt
     7621 tcctagtgag aaagaattgg ggcagaaatt tgtcgtttca gccatcctat cctatgatat
     7681 gaccaaggca gctacagact tggatttaac agcctctgtc cattacggag aattgtgtca
     7741 gcagtggacg acttggtttc aggaaacgag tgaagatttg attgaaacgg tagcctataa
     7801 actggtggaa cgtacctttg agtcttatcc tcttgtccaa gaaatgaagt tggaactgaa
     7861 aaaaccttgg gcaccggtgc atttgtcact agatacttgc tcggtaacca ttcatcgccg
     7921 caagcaacga gcctttatcg ccctaggaag caatatggga gataaacaag taaacttgaa
     7981 gcaagccatt gacaaactgc gagctcgtgg catccatatt ctcaaagagt ccagtgtctt
     8041 agcgacggag ccttggggtg gagtggagca ggatagcttt gccaatcaag tggttgaggt
     8101 ggaaacctgg ctaccagcac aagacttgtt agaaaccttg ttagccattg agtcagagct
     8161 gggacgggtg agagaagtgc attggggacc tcgtttgatt gatttggact tgctctttgt
     8221 ggaggaccag atcctttata cagacgacct catattgcct catccttaca tagcggaacg
     8281 cctttttgtc cttgagtcct tacaggaaat tgcgcctcat tttatccatc cgatattaaa
     8341 acaaccgatc cgtaacttgt atgatgcttt gaaaaaatag aaaaactcta gttttcagtt
     8401 acttgcaact gaaggctaga gtttttaaaa taggtcattt tcttctggga ggaggatagt
     8461 ttctctaccg tccatgtcta aaaccagtac tcttggggga taacgagggt cgaaaggatg
     8521 gttaaagtca aaatcaatgg ctgtagggag gtgttgactt gaaaagtgga aggtaatctt
     8581 tccttggtta ttaagcaatt gaaactcgag ttcttcttcc aattcaaaga cattttttaa
     8641 gaaatggtcg ataatatacc aaaaagagtc aatgatgtca tcaggcaagc tggtaacaat
     8701 gccaaaacta gcagaccgca tgtgggtatt ggtaaaagcc atatctctgt ctcctttctt
     8761 ttcccttatc atacagcaaa taggattaaa aatcaagaaa aggtgatttt ttgaaaagga
     8821 ttttaactac agggaaaaag aaggaaaaaa attcccaaaa atctaccgaa gttaataggt
     8881 aaattcccaa attaacttga ttatataact ttcagttact ttgagaagtt accgaaaaat
     8941 atttttcata tctattgact tttaggggtg aaatttggta tgatagtagg cggtattgtt
     9001 taccccattt gaaaggcccc ggaaccttcc aaatactttt cgatgggaag gaacacccat
     9061 caccgtaaac aaaaatcgaa ctatatatag gagaaatcat gaacaaaaca acatttatgg
     9121 ctaaaccagg ccaagttgaa cgtaaatggt acgtagttga cgcaactgat gtaccacttg
     9181 gacgtctttc tgcagtagtt gctagcgtac ttcgcggaaa aaacaaacca acatttacac
     9241 cacacactga tacaggtgac ttcgtgattg ttatcaatgc tgaaaaagtt aaattgactg
     9301 gtaaaaaagc aactgataaa atctactaca ctcactcaaa ccacccaggt ggattgaaac
     9361 aaatctctgc aggtgaactt cgttctaaaa atgcagtacg tttgattgag aaatcagtta
     9421 aaggtatgct tccacacaat acacttggac gcgctcaagg tatgaagttg aaagtatttg
     9481 ttggagctga gcacactcat gctgcacaac aaccagaagt tcttgacatt tcaggactta
     9541 tctaaggaaa ggaacaaata aagtatgtca caagcacaat atgcaggtac tggacgtcgt
     9601 aaaaacgctg ttgcacgcgt tcgccttgtt ccaggaactg gtaaaatcac tgttaacaaa
     9661 aaagatgttg aagagtacat cccacacgct gaccttcgtc ttgtcatcaa ccaaccattc
     9721 gcagttactt caactgtagg ttcatacgac gttttcgtta acgttgtagg tggtggatac
     9781 gctggtcaat caggagctat ccgtcacggt atcgctcgtg cccttcttca agtagaccca
     9841 gacttccgcg attcattgaa acgcgcagga cttcttacac gtgactcacg taaagttgaa
     9901 cgtaagaaac caggtcttaa gaaagctcgt aaagcatcac aatttagtaa acgttaattc
     9961 gaaagaatta ctatacttat acagagcacc tttcggggtg ttcttttttt atactttctt
    10021 actaaattgg tgcaattgac acagttgttg cgactttagt cgcttacaaa tgtggctgca
    10081 acctgacaag gtcagttgcc tcaaaacgtt aatcaataca attatatcaa cgtttcaaag
    10141 cactcaagag tttacctcat gggtgctttt tttatgtttt ttgaaaaagt tcacctcaaa
    10201 gtttacctta ttttcacctt attgttttag agactgtaag gcaaattcac cgacggccat
    10261 agggactaca ttagaagtat tgacataaat ctgtgttgta cctgtgtcgc tatgtattag
    10321 agcttcagaa atggcttcta agctcattcc tgcttgttta gcgagcgttg ctccggtatg
    10381 acgtagtttg tgtggcgtag cgtgtgtaag ctctgggtgt cgttttctga tagttttcat
    10441 cttattattg agatagtcag aatgtaaagg tttattgata ttgcctttgg tatctatgta
    10501 agtaaagatg aattgttctg gattactgat gataccaaac tttgccagtt catatttttg
    10561 ttgttttttc catgaagtca gaagttgaag taagtcatta gaaatagaga aaatgggaaa
    10621 tgtttccaca ataaaacgca tattatcaga tggttaatgc gttttatatt tgggtttgag
    10681 gcttataaaa taggataagc gtactgaaaa cttagatatg acaaacaaaa taaaattttt
    10741 aaaagctaca tagaaacatg gtataatgta tctaaaggag gtagcatatg tccttagata
    10801 tagataaaga aaagatgaca atcatgggaa tagcttttga aaaccgatcc gtttttagga
    10861 gtgtttggta tgctttaagt acaaatatga ttgaaggatg gcgacctacg gttagtgatg
    10921 ttgaaaaatt acgagatgaa gctcttgctc tggtctgggg atgacttaat gaagcgcaac
    10981 tgttatgaat cttatgacta tgttgatccg gataatttat ataccgatcc gggttcttca
    11041 gttctaagaa ataagcagga aggaaaaaag cacgcgagct tgaatatcgt atgattgcta
    11101 gtaagagttt gaaattattt atcaatccta tcttagttaa tagtttaaaa gtagtttgtt
    11161 tcacaactgc ataagcttag aaaagttgaa aagtgataac tctttaataa actcttggtt
    11221 tgttaaaaga tattttgtcc actacatttt tttcaattga ctattatttg tcatagatat
    11281 aacagataga acattgcatt cagaataatg aaaaacgcat caaaaatggt gcgttctgtt
    11341 tttatgctac cataaaagga ggaaaacaaa ttgaaaattt ttaagggaga gttttatcga
    11401 atctctgtat taacagacaa gctagtaagg ttagaatact ctcaaactgg aagttttgag
    11461 gatagaacga cacaacttat ctataataga gattttggcc aaatttcgtt agattatatc
    11521 gagacatcaa acgtactaga tattatgacg gactattttc atctgcactt taataaagga
    11581 gaatttaacg ccgaaaattt atttatagaa ttaaaaggaa attttgccgt atatggtagt
    11641 cgctggtatt ttggtgaatc tattgaaacg ttaaaaggaa cagctcggac tctggataag
    11701 gcagatggag caatctcgtt agaagatgga attattagcc gaaatggtat agccttattg
    11761 gatgattctc aaggatttat ttgggatgaa caatctggtt atattgagag agaaaatcaa
    11821 attgacctgt atttctttgc ctatgggcat gattatagag gagcaatcag agacttttac
    11881 catttgactg gttcaacacc cttgttgcca agatatgctt taggcaattg gtggagtaga
    11941 tattggcctt atacgtcgga tgaatacttg gatttaatag acagatttga aacagagaaa
    12001 attccattat ctatcggtgt gttagatatg gattggcata taactgacat tccagctcgt
    12061 tttggaagtg gctggacagg atatagttgg aatagaaact taataccaaa tccagaacag
    12121 ttattgcaac aacttcatga tagaaagtta aaactctcct taaatgtcca tcctgctgat
    12181 gggatacggg cttatgaaga agcttatcct caaatcgcaa aacgattggg gttaaatgta
    12241 gaactagaag aacctgctat ttttgatttt tttaatccct cttttaggga agcctacttt
    12301 aaagatgttc attatgagct agaaaagcag ggagtagatt tttggtggat tgactggcaa
    12361 caggggacac aaggcatgct agatccactt tggcttttaa accattatca ctatcaggat
    12421 agttgtaaaa atgcagaagg tggtttgatt ttatcaagat atgcaggtcc tggtagtcac
    12481 cgctaccctg ttggtttttc aggggatact attattagtt ggaattcctt aagatttcaa
    12541 ccctatttta cagcgacagc atctaatatc ggttatagtt ggtggagtca tgatatcggt
    12601 ggacatatgt tgggggatta tgacgaagag ctacaaacta gatggttaca gtttggtgtt
    12661 tttagtccga ttactcgatt acatagttct agaagtcctt ttaatagtaa agaaccttgg
    12721 tttttttcag aaacaacatc taagattatg aagaaatacc ttcgtttgag acatcagatg
    12781 atttcttatc tatataccat gaatgtaaag acacatgagg aaggtgcccc attaatcagt
    12841 ccaatctatt atttctatcc agagaatgat gagagctata atgttccaaa ccaatacttt
    12901 tttggaacag aactgatggt ggctcccatt gtagaaaaga tggatttgac attccaatct
    12961 gcaaaagtag atgtatggtt ccctgaaggt gaatggtatg acttcttttc agagaaaaaa
    13021 tacacaggtg gtgtgaagtt aagtgtttat agagacatct cgactacgcc tgtgtttgca
    13081 aaaagtggtg caatcattcc cttggttggt tctgagatag gtatgggtgt tgatttacct
    13141 gaagttgtag attggtatgt attcccaggc aaacaacatt cttttgaaat gatcgaagat
    13201 caaaatggtc aaagatataa aacaagatta tcaatcgatt gggaaatggg aatggtagag
    13261 ttagcattac aaggagattc tagtatcgtt ccaagcaata gaaaacatag aattcatttt
    13321 aaaggaacga atgtgtctat aattgaattg ccaaataaga atgatacagc taaatttgaa
    13381 tggaaagata ataaaaggac atctttaaat gacgaagttt ttagactact aaagacagct
    13441 tctcttccat atgaattaaa agatagattg ttaaatcaat tcatcaatgc caaaaactct
    13501 catgacttaa tgaatatctt gcatcatcag gataaggaat tgagagggcg tttgttggaa
    13561 atgatattta ctagccaaaa ctaattgaaa taattagaaa gtcatttgtt tagtgtatat
    13621 gaagattctg tatggtattc gttatcactg ctcacattga aaatgtgaaa taagcaccta
    13681 caacatagac tttacaacac ttcatgtttc atatcatggg gtgtttttct atttaagtca
    13741 aagccaatca aaaaatctca ctattcatca ggttaaagga aacctaatca tagtgagatt
    13801 gtgaattata gtagagtttg tatcgcctct tcaatttgtt ttgggtctgt ttttgaagaa
    13861 aagcgttcaa agacttgccc atctcgaccg atgagaaact tagcgaaatt ccattcgatt
    13921 cgttttccta gtgggccgga tttctggtct tttaaccaga catagagagg gtctgcttcc
    13981 ttaccgttga ccttaatctt ggcaaaacgt gggaaggtgg tttgaaaatg taggctacag
    14041 aaggcgttga tttcctctgc gctgccgggt gcttgtccca taaactgatt gcaagggaaa
    14101 tccaatattt cgaagccctg atcttgatag cgttcataga gttcttgaag tccctggtac
    14161 tggggcgtta aaccacatcc agtagcagtg ttgacaatca agagaacttt gccacgatag
    14221 ctatccaagg gagttgcttg gttgttttgg ttcaaaacgg aaaaatcata aagtgaagtc
    14281 atgagggcct cttttctttt tctacattgt aacagttttt acttttttcg tcgagtcgga
    14341 tggaagatat tgttgaagaa taagccctca atatgataga aaccgtttac aaataacttt
    14401 aaaaatggta tgatttaatt aaaccggttt actttgttgc tataaatctc taatttgaga
    14461 tttagttcct attgatttta caatatgttt attggagtgt atacatgcaa acaaaaacaa
    14521 agaagctcat tgtgagtttg tcttcacttg ttttatcagg atttttatta aaccattata
    14581 tgacagttgg agcggaagaa acgactacga ataccattca gcaaagccag aaggaagttc
    14641 agtatcagca aagggataca aaaaatttag ttgaaaatgg tgattttggt cagacggagg
    14701 acggaagcag tccgtggaca ggaagcaaag ctcaggggtg gtcagcttgg gtagaccaga
    14761 agaatagttc tgcagatgcc tcaactcgag tcattgaggc taaggatggg gctatcacta
    14821 tctcaagccc tgagaaatta agggcagcgg ttcaccgtat ggttcctatt gaagctaaga
    14881 aaaagtataa actgcgtttc aagattaaaa cagatcataa agtcgggatt gccaaagttc
    14941 gtatcattga ggaaagtgat aaggacaagc gattgtggaa ttctgcaacg acgtcaggaa
    15001 caaaggactg gcagaccatt gaagcagact atagcccgac tttagatgtt gataaaatca
    15061 agctggagtt attctatgaa acaggaactg ggactgtttc ctttaaggat attgagctgg
    15121 tagaggtagc agaccagcct tctgaggatt ctcaaacaga taaacagctt gaggaaaaga
    15181 ttgatttacc aattggaaaa aaacatgttt tttctcttgc ggactatact tataaggtag
    15241 aaaatcctga cgttgcttca gtcaaaaatg gaattttaga acctcttaag gaagggacaa
    15301 ccaatgtcat tgtcagtaaa gatggcaagg aagtgaaaaa gattcctttg aagattctag
    15361 cctctgttaa ggatgcatac acagaccgtt tggatgactg gaatggcatc atcgctggga
    15421 atcaatacta tgattctaaa aatgaacaga tggccaaatt aaaccaggaa ttggaaggaa
    15481 aggtagctga tagcctatcc agtatttcaa gtcaggcgga ccgcatctat ttgtgggaaa
    15541 aattttcaaa ttataaaacg tctgcaaatc tgactgccac ttatcggaaa ttggaggaga
    15601 tggccaagca agtgaccaat ccttcttctc gttattataa agatgaaact gtcgttcgaa
    15661 cagtcaggga ttccatggaa tggatgcata aacatgtcta caatagtgaa aagagcattg
    15721 ttgggaactg gtgggattat gaaatcggta cacctcgtgc catcaacaat accttgtctc
    15781 tgatgaaaga atacttctct gatgaggaaa ttaaaaaata tacagatgtg attgaaaaat
    15841 ttgtaccaga tcccgaacat ttccgaaaga cgactgataa cccattcaag gctctaggtg
    15901 gaaacttagt tgatatggga agggtaaaag taatagctgg tttactgcgt aaggatgatc
    15961 aagaaatttc ttctaccatt cgctcgattg agcaagtgtt caagttggta gaccaaggtg
    16021 aaggttttta tcaagatgga tcctatatcg accacaccaa tgttgcctat acgggtgctt
    16081 atgggaatgt tttgattgat ggcctgtctc aactgttgcc agtcattcaa aagaccaaga
    16141 atccaagcga taaagataaa atgcaaacca tgtaccactg gattgataaa tcgtttgctc
    16201 ctttgctggt gaatggagag ctgatggata tgagtcgtgg acgctcgatc agtcgtgcaa
    16261 atagcgaggg gcacgtggcc gcagtagaag tactaagagg gattcaccga atagcggata
    16321 tgtctgaagg agaaaccaaa caacgtttgc agagtcttgt gaagaccatt gttcaatcgg
    16381 atagttatta tgatgtcttt aagaatttga agacttataa ggatatcagt ttgatgcaat
    16441 ccttgttaag tgatgcagga gtcgcaagtg ttccaagaac aagttaccta tctgccttta
    16501 acaagatgga taaaacagcc atgtacaatg cagagaaagg gtttggattt ggcttgtcac
    16561 tcttttccag tcgtaccttg aattacgaac acatgaacaa ggaaaataaa cgtggttggt
    16621 atacgagtga tgggatgttc tatctttaca atggcgattt gagtcactat agcgatggct
    16681 actggccaac agttaatcca tataagatgc ctggtacaac agagacggat gctaagagag
    16741 cggatagcga tacaggtaaa gttttaccgt ctgctttcgt tggaacgagc aaactagatg
    16801 atgccaatgc gacagcaacc atggatttca ccaactggaa tcaaacattg actgctcata
    16861 agagctggtt tatgctaaag gataagatcg cctttttagg aagcaatatc caaaacactt
    16921 caacagatac tgctgcaact acaattgacc agagaaaact ggaatcaagt aattcatata
    16981 aagtctatgt caatgataaa gaagcctccc ttacagaaca agaaaaggat tatcctgaaa
    17041 cccaaagtgt ctttttagaa tcgtccgatt cgaaaaagaa tattggttac tttttcttta
    17101 agaagagttc aatcagtatg agtaaggctt tgcaaaaggg agcctggaag gatatcaatg
    17161 aaggacagtc agacaaggaa gttgaaaatg aatttcttac gattagtcag gctcataagc
    17221 aaaatggaga ttctcatggc tatatgctca ttcctaacgt ggatcgtgcc accttcaatc
    17281 aaatgataaa agagttagaa agtagcctca tcgaaaataa cgaaaccctt cagtctgttt
    17341 atgatgccaa acaaggagtt tggggcattg tgaaatatga tgattctgtc tctactattt
    17401 ccaaccaatt ccaagttttg aaacgtggag tctataccat tcgaaaagaa ggggatgaat
    17461 ataagattgc ctactataat cctgaaaccc aggaatcagc tccagatcag gaagtcttta
    17521 aaaagctaga gcaagcagct cagccacaag tacagaattc aaaagaaaag gaaaaatctg
    17581 aagaggaaaa gaaccattcg gatcaaaaga atctccctca gacaggagaa ggtcagtcaa
    17641 tcttggcaag tctagggttc ttgctacttg gggcgtttta tctattccgt agaggaaaga
    17701 acaactaatt tgttcatcat ctagatgaat tacatgaaac tgtggaaaat agaaaaaatc
    17761 cgaagaaggc caaatatctt cggatttttc ttttaaaaaa ggataagttg atacttatcc
    17821 tttttacttc attatgtgac tatagcgttt tgaaactaga ataggacatc ataactgcta
    17881 aaagatttct ataaattcat ttgattttcc taatcaattt gttcgtatcc tatttcactc
    17941 tactatatta gtccgtctcg cacctcacgg agcgagacaa aacaaccacc cgctatgcgg
    18001 gtgcgcgtcg aaggttatac caaaaaaact ccaaacgcga tacaataaag gtgttcaacc
    18061 cacttgtaaa gcgaaaggag aaaaaatatg gcacaaaagg ctcatagttt atctcacaca
    18121 aagtggaggt gttctatcac attgtgttca cccctaagta tagacgaaaa gtcatctata
    18181 atcaatatag aagtagttta ggcgaaatat ttcatcgctt gtgtagttat aaaggtgttg
    18241 aaatgatcga gggtcactta atgccagacc atgtacacat gttagtcagt attccactaa
    18301 ggctaagtgt ttcgagtttc atgggttatt taaaaggcaa aagtgcactc atgatgtttg
    18361 acaaacacgc caatctcaag tacaagtttg ggaatcggca tttctgggcg gaaggttatt
    18421 atgtaagtcc agtagggctt aatgaagaca caattaagaa atatagtcaa gattaaagaa
    18481 attatcgagt ggatgatttc ttcacgagta tgaaaatttg agaactagta aagtatgata
    18541 tatagtaaaa tgaaataaga acaggacaaa atcgatcagg acagtcaaat cgatttttaa
    18601 caatgtttta gaagtagagg tgtactattc cagtttcaat ctactatagc actagataaa
    18661 ttgagtgtaa aagaatatga ggatcccttt agggatagtg gtaagtaata ccaaagtctc
    18721 ttaaagaggc aagtgacgag tcaagagcaa taaggcttga acaacgtgaa agccagcgtc
    18781 tttaggcgct ggctgatgat ttgggcttat agctctgaga taaaccaccc gttagacggg
    18841 tagttatgat tttatctgag tgtaacatac tgttgggcaa tctcgctgat gcggtcaaag
    18901 ttgccttggg aagcgagttt attgagttcg ccaccaattc caacggcatc tgcaccagca
    18961 gcgaaccatt gagggatgtt gtttagaccg actcctccgg ttaccattac ggaaacttgt
    19021 ggaatcggtg ccttgactgc agagatatat gctggactga gagtactacc tgggaagagt
    19081 ttgatgattt cactaccggc ttcaagtgca gtcgtgatct ctgtgagggt aatacagcct
    19141 ggaatgtacg gtgtgctgta gagattgcac attttcgcag tttcagcatg gaaagatgga
    19201 gaaacaacgt aatttgctcc ggctagaatg gcatctctag cagttacggc atcaagcaca
    19261 gtacctgcac cgatacaaac actctgatcg tcctgataca agtctacaag ttccttgatg
    19321 atttgtcctg catactgatt ggtataggcg atttcaatag ctttgatacc gcccttgata
    19381 caagcaatcg aggcttgtag tccttcttcc tttgtatttc ctcgaatgac agcaacaatt
    19441 ttctgttttt ttagttcaat aattgtatct gatttggtca tgtaattctc ctaacgaatg
    19501 atatcttgtg catttgccag taaattttca atactagttg cggaagtgga gagatggtct
    19561 cctggaagag tgcatttgag agttgcgctc gcaactgcaa agtcaatggt agtttttagg
    19621 gaggaatgat ggagtagttg gtaaagggca ccagatataa aggcatcccc gctaccaatt
    19681 cgttgataga ctgcagtttt tagttggaca gactcttcaa atcgttcttc cagagcatag
    19741 gcttgataga catttttgtc ttgctcatca ctagagcgga gggtatggaa aatggccttg
    19801 aaaccatagg cttcttttaa aagtcgcatg cgattttcca cctcttctag gctagcactg
    19861 tctcttggaa acatctctag attttggtca tcaatcatga gaggatcaat accgaagcaa
    19921 tagtcagtaa aacgtgcaaa cttagaaaat tcatacttgg cttctaggac tgaaatcatc
    19981 tttgttctca gattgagatc cattgaaacg acaattcctc ggcgcttggc ttcttccaag
    20041 agtaggagaa ggatcgcacg gacctcttga ccgatagcta cggtgattcc actaaaatga
    20101 aaatggctaa tcccctgaaa gagagaatcc atatctagca tgtttggccg aatctggctg
    20161 atactcgtat gcttacgatc gtagaaaact tcactttgac gacaaccaaa gccgttctcc
    20221 aaatagtaga ggccgattcg atcgccaagc cgacagattg aactggtatc gatttggtgc
    20281 tgtttcaaga atgtgagaaa acgatctcca atctcgttgg cagggagtgc ggtaaagact
    20341 ttcgttgaga tacccagggc ttgcaaatta caagcgatgt taatttctga tccgccaaaa
    20401 taagtcgaac tggcaacatg atctccgata ctggtggcat ctaatggtga gattcgaatt
    20461 aatggttcgc caaacagtaa tattttcgtc atccattagt tcctttctgg tttagaatag
    20521 ctttacttgg ctaatacttc tttcaaataa gcagcgactt catcatcttg gcagttttca
    20581 aagaagtatt cttggaagta tttgccagat atggtgtctt tgaggaagtc ttggtcgatt
    20641 gttttaagga tggtcatcaa atcattgtgg gtgatttgtt tcacctcgtt taagatacga
    20701 gcgttgcgtt gttcagggat tacacgttct cttgggtagc caccgcccat ttcttcagca
    20761 aataagcgtt caaacatcaa tttgagggtc agttctgccc cccagccaaa tcctttggca
    20821 taagggatag acaaggcgtt accaccattg atttgagaat aaaggtaagc gtcagttggg
    20881 tccactgcta gaccacagac aacaccaggg aagctgttta aagcaagcat agcccctaca
    20941 cccgtaccac agccggtaac aacaaagtca actgcctttg tatttaaaag gatggcagcc
    21001 attagtccgt tctgcacata agttaattga ctttctcctt cttctccacg cataccatag
    21061 ttaaataatt ggtagtcttt tttatctgtc gcttctttta gactatcgta aataatgtga
    21121 ttcttgctag cttgactatt ttcattgatt aatgcgattt tcataagatc ttctttctat
    21181 ttttactcag gttgttttcc gatgtaggct aagataccgc catctacata taggatgtgg
    21241 ccattgacaa aattgctggc atcactagcg agaaagacag cagggcccat caaatcttca
    21301 ggatttcccc aacgtgcagc aggtgttttt gcaatgatga actggtcaaa tgggtggcga
    21361 gaaccatctt cttgcaactc acgaagaggt gctgtttgag gagtggcaat ataacccggt
    21421 ccaattccgt tacattggat attggctcca ccgtattcag acgcaatgtt gcgggtcaac
    21481 attttcaagc cccctttagc agcagcataa gcgctaactg tttcacgtcc cagttcgctc
    21541 atcatcgaac aaatattgat aatctttcca tgccctttct ttatcataga aggaataact
    21601 gcctttgaaa cgataaatgg tgcgtttaag tcaatatcga tgaccttacg gaaatcagcg
    21661 gcgctcattt cgcacattgg aactcggcgg ataataccag cgttattaac gaggatgtca
    21721 atgacaccaa cctcttgttc gatttgcttg accatggctt ggataccgtc ctcgtctgtc
    21781 acgtcacaga catatccatg ggcttcgatg ccaacttcac gataagcttc aatcccttta
    21841 ttgaccagat cttgattgat atcgttaaag acaatagtag cgccggcttc agcgtaggat
    21901 ttggcaatag caaatccaat tccataagaa gcgccggtga tgagagcaat ttttcctttt
    21961 aaagaaaact gctcaattga gaatgatgta tttgtcattt gatacttcct ttcaaatttg
    22021 ttaagacttc tctataacca aattatattc tag
//
LOCUS       DBEJAU010000036        21048 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC323 isolate 683620
            SAMN38261939-rid24807223.denovo.036, whole genome shotgun sequence.
ACCESSION   DBEJAU010000036 DBEJAU010000000
VERSION     DBEJAU010000036.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261939
            Sequence Read Archive: SRR26833919
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 21048)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 21048)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576303.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576303.1
            Genome Coverage       :: 154x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/19/2025 01:05:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,121
            CDSs (total)                      :: 2,078
            Genes (coding)                    :: 1,943
            CDSs (with protein)               :: 1,943
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 36
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 72 of 135
            Pseudo Genes (incomplete)         :: 63 of 135
            Pseudo Genes (internal stop)      :: 51 of 135
            Pseudo Genes (multiple problems)  :: 46 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..21048
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261939-rid24807223.denovo.036"
                     /strain="GPSC323"
                     /isolate="683620"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            149..583
                     /locus_tag="ACL29Z_001429"
     CDS             149..583
                     /locus_tag="ACL29Z_001429"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000706826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HGR0069721.1"
                     /translation="MKIVLVGHGHFATGIYSSLQLIAGNQESVEAIDFVEGMSADELK
                     QKILLAISNEEEVLILSDLLGGSPFKVSSTIMGENPAKTMNVLSGLNLAMLMEAVFVR
                     MAHSFDEVVNKSVVAAQGGVVNGKELFSTDAEEEEEDFESGI"
     gene            595..1785
                     /locus_tag="ACL29Z_001430"
     CDS             595..1785
                     /locus_tag="ACL29Z_001430"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003074342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 88 protein"
                     /protein_id="HGR0069722.1"
                     /translation="MIKKVTIEKIKSPERFLEVPLLTKEEVGQAIDKVIRQLELNLDY
                     FKEDFPTPATFDNVYPIMDNTEWTNGFWTGELWLAYEYSQQDAFKNIAHKNVLSFLDR
                     VNKRVELDHHDLGFLYTPSCMAEYKINGDGEAREATLKAADKLIERYQEKGGFIQAWG
                     DLGKKEHYRLIIDCLLNIQLLFFAYQETGDQKYYDIAESHFYASANNVIRDDASSFHT
                     FYFDPETGQPFKGVTRQGYSDDSCWARGQSWGVYGIPLTYRHLKDESCFDLFKGVTNY
                     FLNRLPKDHVSYWDLIFNDGSDQSRDSSATAIAVCGIHEMLKHLPEVDADKDIYKHAM
                     HAMLRSLIEHYANDQFTPGGTSLLHGVYSWHSGKGVDEGNIWGDYYYLEALIRFYKDW
                     NLYW"
     gene            1796..2287
                     /locus_tag="ACL29Z_001431"
     CDS             1796..2287
                     /locus_tag="ACL29Z_001431"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000178618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HGR0069723.1"
                     /translation="MTMPNIIMTRIDERLIHGQGQLWVKYLGCNTVIVANDEVSTDKM
                     QQTLMKTVVPDSVAMRFFPLQKVIDIIHKANPAQTIFIVVKDVKDALTLVEGGVPIKE
                     INIGNIHNATGKEQVTRSIFLGEEDKAALKELSQTHQVTFNTKTTPTGNDGAVQVNIM
                     DYI"
     gene            2302..3081
                     /locus_tag="ACL29Z_001432"
     CDS             2302..3081
                     /locus_tag="ACL29Z_001432"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000026606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS
                     mannose/fructose/sorbose/N-acetylgalactosamine transporter
                     subunit IIC"
                     /protein_id="HGR0069724.1"
                     /translation="MSINVFQAILIGLWTAFCFSGMLLGIYTNRCIVLSFGVGIILGD
                     LPTALAMGAIGELAYMGFGVGAGGTVPPNPIGPGIFGTLMAITSAGKVSPEAALALST
                     PIAVAIQFLQTFAYTVRAGAPETAMKHLKNHNLKKFKFTLNATIWLFAFIGFTLGCLG
                     ALSMDTLLKLVDYIPPVLLTGLTVAGKMLPAIGFAMILSVMAKKELIPFVLLGYVCAA
                     YLNIPTIGIAIVGTIFALIEFYNKPKTADHVVEEEAHDDWI"
     gene            3068..3886
                     /locus_tag="ACL29Z_001433"
     CDS             3068..3886
                     /locus_tag="ACL29Z_001433"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000148012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HGR0069725.1"
                     /translation="MTGSNKLTKRDYLKTSLRAFFCQNGFNYSNYQGLGYANVMYPAL
                     KKHYGEDQEGFYQALEENCEFYNTNPHFLPFITSLHLVMLENGRPAKETRSIKMALMG
                     PLAGIGDSLSQFCLAPLFSTIAASFAQEGLVVGPILFFLAMNTILTAIKLSTGLYGYK
                     LGTTVIDKLSEQMATISRIANIIGVTVIAGLAATSVKIMVPITFAAGEVKADAKQSIV
                     SIQGMLDKVAPALLPALFTLLVYYLIKEKKWTTYKLVILTVIIGIIGSWLKIIA"
     gene            3886..4179
                     /gene="yajC"
                     /locus_tag="ACL29Z_001434"
     CDS             3886..4179
                     /gene="yajC"
                     /locus_tag="ACL29Z_001434"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000381741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_process: GO:0015031 - protein transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit YajC"
                     /protein_id="HGR0069726.1"
                     /translation="MDTTLFYGIVIVLAVSPLLLSSFHSIRQQKLLRKQMEQRQEYLA
                     SLTSGDEVLLLSGIHGKIISIKDDLVSLQIAKGVVIYVEKESVMGKTKELLFK"
     gene            4201..6102
                     /locus_tag="ACL29Z_001435"
     CDS             4201..6102
                     /locus_tag="ACL29Z_001435"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000657070.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alginate lyase family protein"
                     /protein_id="HGR0069727.1"
                     /translation="MKEERRQFFERVDGNQCRDYILSHCSKDYEKVKSSLERLMNNRF
                     MFDSPWDMEPCSKIHQIQPMVWDQVFEDDPEWAYMLNRQEYLLQFMIGYLVEGDKSYI
                     QKCKFFLFDWIEQVREFSPQSLMTRTLDTGIRSFTWLKLLLLLLKFDLLEEKELEKIL
                     VSLEKQIDFMKSYYRAKYTLSNWGILQTIPMLAIYHFFSDKMDLEEAYHFASEELKQQ
                     IETQILGDGSQFEQSILYHVEVYKALLDLCLLLPDLQDSYRELLEKMATYIQMMTGLD
                     GRTLAFGDSDSTETTEMLSLSAVVLNKEDLLNGLDVKVDLLSLLFLGREKVKRLQEFE
                     RRAWQPKSMIFEDSGHVCIKDEHRYLFFKNGPLGSAHSHSDENSFCLQYQGQPIFIDA
                     GRYSYREIYERYLLKSAWSHSTCIVDGKAPERITGSWEYEYYPHSLFCHHKEREGVHY
                     IEGAYWSAEPDLPYLHKRKILMLVEDVWLLVDDIRCQGQHEALTQFILDKDVTYQDGK
                     INQLRLWSEVDFDLEDTIISPKYNELERSSKLTKRQFFENQMLDYTIIAHESFEIIRH
                     SVYQTDDREVENALAFEVKNDETDKLILLLSEDIGVGEKLCLVDGTKMRGKCLVYDKI
                     NERMIRLQC"
     gene            6162..7163
                     /locus_tag="ACL29Z_001436"
     CDS             6162..7163
                     /locus_tag="ACL29Z_001436"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000412458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HGR0069728.1"
                     /translation="MEKKLTIKDIAEMAQTSKTTVSFYLNGKYEKMSQETREKIEKVI
                     HETNYKPSIVARSLNSKRTKLIGVLIGDITNSFSNQIVKGIEDIASQNGYQVMIGNSN
                     YSQESEDRYIESMLLLGVDGFIIQPTSNFRKYSRIIDEKKKKMVFFDSQLYEHRTSWV
                     KTNNYDAVYDMTQSCIEKGYEHFLLITADTSRLSTRIERASGFVDALTDANMRHASLT
                     IEDKHTNLEQIKEFLQKEIDPDEKTLVFIPNCWALPLVFTVIKELNYNLPQVGLIGFD
                     NTEWTCFSSPSVSTLVQPSFEEGQQATKILIDQIEGRNQEERQQVLDCSVNWKESTF"
     gene            complement(7273..7608)
                     /locus_tag="ACL29Z_001437"
     CDS             complement(7273..7608)
                     /locus_tag="ACL29Z_001437"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000838135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0069729.1"
                     /translation="MKSLARLLIIHVFISIFLFFALISGAVSHTVLLLLLLFLPALNK
                     GLEKIQSKRIPVLNAALFFLLISFPQLLTNPVQWKFSIFLVVTIISSLAYFYNFYQVV
                     KEVDQKQLI"
     gene            complement(7619..7861)
                     /locus_tag="ACL29Z_001438"
     CDS             complement(7619..7861)
                     /locus_tag="ACL29Z_001438"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0069730.1"
                     /translation="MKKEKKQLRYPGLKAGSIYGTVIFFIIPLIDTLTSENPNFISSL
                     LNTKHIFKTILGAFFFGVMIHIVDSLRIARAKKDQD"
     gene            complement(7877..8071)
                     /locus_tag="ACL29Z_001439"
     CDS             complement(7877..8071)
                     /locus_tag="ACL29Z_001439"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001082472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HGR0069731.1"
                     /translation="MNRVKEFRKELGISQLELAKDIGVSRQTINMIENDKYNPTLELC
                     LNLARSLQTDLNSLFWKEDF"
     gene            8237..9187
                     /gene="rsmH"
                     /locus_tag="ACL29Z_001440"
     CDS             8237..9187
                     /gene="rsmH"
                     /locus_tag="ACL29Z_001440"
                     /EC_number="2.1.1.199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466808.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016434 - rRNA (cytosine)
                     methyltransferase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (cytosine(1402)-N(4))-methyltransferase
                     RsmH"
                     /protein_id="HGR0069732.1"
                     /translation="MTKEFHHVTVLLHETIDMLDVKPDGIYVDATLGGAGHSEYLLSK
                     LSEKGHLYAFDQDQNAIDNAQKRLAPYIEKGMVTFIKDNFRHLQARLREAGVQEIDGI
                     CYDLGVSSPQLDQRERGFSYKKDAPLDMRMNQDASLTAYEVVNHYDYHDLVRIFFKYG
                     EDKFSKQIARKIEQAREVKPIETTTELAEIIKLVKPAKELKKKGHPAKQIFQAIRIEV
                     NDELGAADESIQQAMDMLALDGRISVITFHSLEDRLTKQLFKEASTVEVPKGLPFIPD
                     DLKPKMELVSRKPILPSAEELEANNRSHSAKLRVARKIHK"
     gene            9199..9516
                     /gene="ftsL"
                     /locus_tag="ACL29Z_001441"
     CDS             9199..9516
                     /gene="ftsL"
                     /locus_tag="ACL29Z_001441"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000840841.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0000910 - cytokinesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsL"
                     /protein_id="HGR0069733.1"
                     /translation="MAEKMEKTGQILQMQLKRFSRVEKAFYFSIAVTTLIVAISIIFM
                     QTKLLQVQNDLTKINAQIEEKKTELDDAKQEVNELLRAERLKEIANSHDLQLNNENIR
                     IAE"
     gene            9520..11772
                     /gene="pbp2X"
                     /locus_tag="ACL29Z_001442"
                     /gene_synonym="pbpX"
     CDS             9520..11772
                     /gene="pbp2X"
                     /locus_tag="ACL29Z_001442"
                     /gene_synonym="pbpX"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000872287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein 2X"
                     /protein_id="HGR0069734.1"
                     /translation="MKWTKRVIRYATKNRKSPAENRRRVGKSLSLLSVFVFAIFLVNF
                     AVIIGTGTRFGTDLAKEAKKVHQTTRTVPAKRGTIYDRNGVPIAEDATSYNVYAVIDE
                     NYKSATGKILYVEKTQFNKVAEVFHKYLDMEESYVREQLSQPNLKQVSFGAKGNGITY
                     ANMMSIKKELEAAEVKGIDFTTSPNRSYPNGQFASSFIGLAQLHENEDGSKSLLGTSG
                     MESSLNSILAGTDGIITYEKDRLGNIVPGTEQVSQRTMDGKDVYTTISSPLQSFMETQ
                     MDAFQEKVKGKYMTATLVSAKTGEILATTQRPTFDADTKEGITEDFVWRDILYQSNYE
                     PGSTMKVMMLAAAIDNNTFPGGEVFNSSELKIADATIRDWDVNEGLTGGRMMTFSQGF
                     AHSSNVGMTLLEQKMGDATWLDYLNRFKFGVPTRFGLTDEYAGQLPADNIVNIAQSSF
                     GQGISVTQTQMIRAFTAIANDGVMLEPKFISAIYDPNDQTARKSQKEIVGNPVSKDAA
                     SLTRTNMVLVGTDPVYGTMYNHSTGKPTVTVPGQNVALKSGTAQIADEKNGGYLVGVT
                     DYIFSAVSMSPAENPDFILYVTVQQPEHYSGIQLGEFANPILERASAMKDSLNLQTTA
                     KALEQVSQQSPYPMPSVKDISPGDLAEELRRNLVQPIVVGTGTKIKNSSAEEGKNLAP
                     NQQVLILSDKAEEVPDMYGWTKETAETFAKWLNIELEFQGSGSTVQKQDVRANTAIKD
                     IKKITLTLGD"
     gene            11774..12754
                     /gene="mraY"
                     /locus_tag="ACL29Z_001443"
     CDS             11774..12754
                     /gene="mraY"
                     /locus_tag="ACL29Z_001443"
                     /EC_number="2.7.8.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000470804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008963 -
                     phospho-N-acetylmuramoyl-pentapeptide-transferase activity
                     [Evidence IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phospho-N-acetylmuramoyl-pentapeptide-
                     transferase"
                     /protein_id="HGR0069735.1"
                     /translation="MFISISAGIVTFLLTLVGIPAFIQFYRKAQITGQQMHEDVKQHQ
                     AKAGTPTMGGLVFLITSVLVAFFFALFSSQFSNNVGMILFILVLYGLVGFLDDFLKVF
                     RKINEGLNPKQKLALQLLGGIIFYLFYERGGDILSVFGYPVHLGFFYIFFALFWLVGF
                     SNAVNLTDGVDGLASISVVISLSAYGVIAYVQGQMDILLVILAMIGGLLGFFIFNHKP
                     AKVFMGDVGSLALGGMLAAISMALHQEWTLLIIGIVYVFETTSVMMQVSYFKLTGGKR
                     IFRMTPVHHHFELGGLSGKGNPWSEWKVDFFFWGVGLLASLLTLAILYLM"
     gene            12968..13108
                     /locus_tag="ACL29Z_001444"
     CDS             12968..13108
                     /locus_tag="ACL29Z_001444"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0069736.1"
                     /translation="MVDRTDEVSSKHGFEVVDKAKLMWFEEIFEECKKYWSVKVKILD
                     LF"
     gene            13364..15469
                     /locus_tag="ACL29Z_001445"
     CDS             13364..15469
                     /locus_tag="ACL29Z_001445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001063457.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HGR0069737.1"
                     /translation="MNNNFNNFNNMDDLFNQLMGGMRGYSSENRRYLINGREVTPEEF
                     AHYRATGQLPGNAETDVQMPQQASGMKQDGVLAKLGRNLTAEAREGKLDPVIGRNKEI
                     QETSEILSRRTKNNPVLVGDAGVGKTAVVEDLAQAIVNGDVPAAIKNKEIISIDISGL
                     EAGTQYRGSFEENVQNLVNEVKEAGNIILFFDEIHQILGAGSTGGDSGSKGLADILKP
                     ALSRGELTVIGATTQDEYRNTILKNAALARRFNEVKVNAPSAENTFKILQGIRDLYQQ
                     HHNVILPDEVLKAAVDYSVQYIPQRSLPDKAIDLVDVTAAHLAAQHPVTDVHAVEREI
                     ETEKDKQEKAVEAEDFEAALNYKTRIAELEKKIENHTEDMKVTASVNDVAESVERMTG
                     IPVSQMGASDIERLKDMAHRLQDKVIGQDKAVEAVARAIRRNRAGFDEGNRPIGSFLF
                     VGSTGVGKTELAKQLALDMFGTQDAIIRLDMSEYSDRTAVSKLIGTTAGYVGYDDNSN
                     TLTERVRRNPYSIILLDEIEKADPQVITLLLQVLDDGRLTDGQGNTVNFKNTVIIATS
                     NAGFGYEANLTEDADKPELMDRLKPFFRPEFLNRFNAVIEFSQLTKEDLSKIVDLMLA
                     EVNQTLAKKDIDLVVSQAAKDYITEEGYDEVMGVRPLRRVVEQEIRDKVTDFHLDHLD
                     TKHLEADMEDGVLVIREKA"
     gene            15921..16264
                     /locus_tag="ACL29Z_001446"
                     /pseudo
     CDS             15921..16264
                     /locus_tag="ACL29Z_001446"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000040325.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="group II intron maturase-specific
                     domain-containing protein"
     gene            complement(16331..16813)
                     /locus_tag="ACL29Z_001447"
     CDS             complement(16331..16813)
                     /locus_tag="ACL29Z_001447"
                     /EC_number="4.4.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002893508.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S-ribosylhomocysteine lyase"
                     /protein_id="HGR0069738.1"
                     /translation="MSKEVIVESFELDHTIVKAPYVRLIGEETGPKGDIISNYDIRLV
                     QPNEDSIPTAGLHTIEHLLAKLIRTRIDGMIDCSPFGCRTGFHMIMWGRHTSAKIAAV
                     IKDSLKEIAETTTWEDVPGTTIESCGNYKDHSLFSAKEWAKLILEQGISDDAFERHVI
                     "
     gene            complement(16908..18392)
                     /locus_tag="ACL29Z_001448"
     CDS             complement(16908..18392)
                     /locus_tag="ACL29Z_001448"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008535024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1846 domain-containing protein"
                     /protein_id="HGR0069739.1"
                     /translation="MKKQAFSSEQYLNLQRDHILERINQFDGKLYLEFGGKMLEDFHA
                     ARVLPGYEPDNKIKLLQELKEQVEVVIAINASNIEHSKARGDLGISYDQEVLRLIDKF
                     NELGIFVGSVVITQYAGQPAADAFRNQLEKNGIDSYLHYPIKGYPTDMDHIISSEGMG
                     KNDYIKTSRNLIVVTAPGPGSGKLATCMSNMYHDQINGIKSGYAKFETFPVWNLPLHH
                     PVNLAYEAATADLDDVNMIDPFHLQTYGETTVNYNRDIEIFPVLKRMLERILGKSPYA
                     SPTDMGVNMVGFAITDDEAAVEASKQEIIRRYYQTVLDFKAEKVGEAAVKKIELLMND
                     LGITPADRKVAVVARQKAEETGGPALAFELPNGEIVTGKNSELFGPTAAALINAIKKS
                     ADIAKEVKLIEPEVVKPIQGLKIDHLGSRNPRLHSNEILIALAITATENPDAARAMEE
                     LGNLKGSEAHSTIILTDEDQNVLRKLGINVTFDPYYQYDRLYRK"
     gene            18545..20152
                     /locus_tag="ACL29Z_001449"
     CDS             18545..20152
                     /locus_tag="ACL29Z_001449"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-glucosidase"
                     /protein_id="HGR0069740.1"
                     /translation="MQEKWWHNAVVYQVYPKSFMDSNGDGVGDLPGITSKLDYLAKLG
                     ITAIWLSPVYDSPMDDNGYDIADYQAIAAIFGTMEDMDQLIAEAKKRDIRIIMDLVVN
                     HTSDEHAWFVEACENSNSPERDYYIWRDEPNDLDSIFSGSAWEYDEKSGQYYLHFFSK
                     KQPDLNWENEKLRQKIYEMMNFWIDKGIGGFRMDVIDMIGKIPDEKVVNNGPMLHPYL
                     KEMNQATFGDKDLLTVGETWGATPEIARLYSDPKGQELSMVFQFEHIGLQYQEGQPKW
                     HYQKELNIAKLKEIFNKWQTELGVEDGWNSLFWNNHDLPRIVSIWGNDQEYREKSAKA
                     FAILLHLMRGTPYIYQGEEIGMTNYPFETLDQVEDIESLNYAREALEKGVPIEEIMDS
                     IRVIGRDNARTPMQWDESKNAGFSTGQPWLAVNPNYKMINVQEALANPDSIFYTYQKL
                     VQIRKENSWLIRADFELLDTADKVFAYIRKDGDRRFLVVANLSNEEQDLTVEGKVKSV
                     LIENTAAKEVFEKQILVPWDAFCVELL"
     gene            20311..20484
                     /locus_tag="ACL29Z_001450"
     CDS             20311..20484
                     /locus_tag="ACL29Z_001450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001022221.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S-ribosylhomocysteinase"
                     /protein_id="HGR0069741.1"
                     /translation="MNIKKRVLSAGLTFASALLLAACDQSGSDTKTYSSTFSGNPTTF
                     NYLLDYYADNIVN"
     gene            complement(20477..21048)
                     /locus_tag="ACL29Z_001451"
                     /pseudo
     CDS             complement(20477..21048)
                     /locus_tag="ACL29Z_001451"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="frameshifted; internal stop; incomplete; missing
                     N-terminus; Derived by automated computational analysis
                     using gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /pseudo
                     /codon_start=2
                     /transl_table=11
                     /product="IS630 family transposase"
BASE COUNT         6357 a         3785 c         4784 g         6122 t
ORIGIN      
        1 tattttgaaa tttctgtcta ttaaaatggt taaaaagata atgaaagcgc taatattttt
       61 ttaaaaaaac tattgacaag ataaaaataa aggattacaa tggggaatat aaagtaaacc
      121 ggtaaaccta aacaagaaag gagaaaagat gaaaattgta cttgtagggc atggacattt
      181 tgctacaggg atttatagtt ctttacaatt gattgcaggc aatcaagaaa gtgtggaggc
      241 gattgacttt gtggaaggaa tgtcagcaga tgaactcaag caaaaaatct tacttgcaat
      301 ttcaaatgaa gaagaagttt taatcctaag tgatctcttg ggaggatcgc cattcaaggt
      361 ttcttctacc ataatgggag aaaatccagc caaaacaatg aatgttctct cgggtttgaa
      421 cttagccatg ttaatggaag cagtctttgt tagaatggct catagctttg atgaagttgt
      481 taataaatca gtagtggcgg cccagggcgg agtcgtaaat ggtaaagaat tgttttcaac
      541 ggatgcagag gaagaggaag aagatttcga atcgggtatt taaagggtaa aagaatgata
      601 aaaaaggtta cgattgaaaa aataaaatcg cctgagcgct tcttagaagt accacttctg
      661 acgaaagaag aagtcggcca ggcaatcgat aaggttattc ggcagttaga actcaacctt
      721 gactatttca aggaagattt cccgacacca gctacctttg ataatgtcta tccaatcatg
      781 gataacacgg aatggaccaa tggtttctgg acaggagaac tgtggttggc ttatgaatac
      841 agtcaacagg atgcatttaa aaacatcgct cataaaaatg ttctttcttt cctggatcgt
      901 gtcaataaga gagtagaatt ggatcaccat gatctcggct tcttgtacac accgtcttgt
      961 atggctgaat ataagataaa tggagatgga gaggctagag aagcaacctt gaaagctgca
     1021 gataagttga ttgaacgcta tcaagaaaaa ggtggtttta ttcaagcttg gggagacttg
     1081 ggcaagaaag agcattaccg tttgattatc gactgcttgc tcaatatcca actcttattc
     1141 tttgcttatc aagaaacagg cgatcaaaaa tactacgata ttgcagaaag ccatttctat
     1201 gcttcagcta ataatgtaat ccgtgatgac gcttcgtcct tccacacctt ctattttgat
     1261 cctgagacag gtcaaccctt taaaggtgta acgagacaag ggtatagtga tgattcatgc
     1321 tgggcacgtg gtcagtcatg gggagtctat ggtattcctt tgacttatcg tcacttaaaa
     1381 gacgagtcct gctttgactt gtttaagggt gtgaccaatt atttcttgaa tcgtctgcca
     1441 aaagatcatg tgtcctattg ggatttgatt tttaatgatg gtagtgatca atcacgagat
     1501 tcttcagcaa cagctatcgc cgtctgtggg attcatgaaa tgctaaaaca tctcccagag
     1561 gtggatgctg acaaagatat ttataaacat gctatgcatg ccatgcttcg ttccttgatc
     1621 gaacattatg caaatgatca atttacccct ggtgggacaa gtctcctcca cggtgtgtac
     1681 tcatggcatt caggtaaagg agtggatgaa ggcaatatct ggggtgacta ctattaccta
     1741 gaagccctta tccgtttcta caaagactgg aacctatatt ggtaggagga gaaatatgac
     1801 aatgccaaat attattatga cccgtatcga tgaacggttg attcatgggc aaggacaact
     1861 ttgggtaaaa tacctaggtt gtaatacggt cattgttgcc aatgacgaag taagcacaga
     1921 caagatgcaa caaactctga tgaaaacagt tgtgccagac tcagttgcca tgcgtttctt
     1981 ccctttgcaa aaggtgattg atatcattca caaggctaat cctgctcaaa cgatctttat
     2041 cgttgtaaag gatgtgaagg acgctttaac cttggtagaa ggtggtgtcc ctatcaaaga
     2101 aatcaatatt gggaacattc acaatgctac tggtaaagag caagtgacac gctccatctt
     2161 cctgggtgaa gaggacaagg cggccctcaa ggaattgagc caaactcatc aagtaacatt
     2221 taatacgaaa acaactccaa caggaaatga tggagctgtt caagtcaaca ttatggacta
     2281 tatttaaaag aggagatcgt tatgtcgatt aatgtatttc aagcgatttt aattggatta
     2341 tggacagctt tctgttttag tggaatgctg ttaggaattt acaccaatag atgtattgtt
     2401 ctgtcatttg gtgtcggaat tattctaggt gatctgccta ctgctcttgc aatgggagct
     2461 attggtgaat tggcttatat gggattcggt gttggtgctg gaggtactgt tccaccaaac
     2521 ccaatcggac ctggtatctt tggtaccttg atggctatca ctagtgctgg taaagtcagt
     2581 ccagaagcgg ctcttgccct ctctactccg attgctgtgg cgattcaatt cttacaaact
     2641 ttcgcctaca ctgtacgtgc tggtgcgcct gaaacggcga tgaagcactt gaaaaaccat
     2701 aatttgaaga aatttaagtt tactctaaat gcaacaattt ggttgtttgc ctttattgga
     2761 tttaccttgg gttgcttggg tgccctttca atggatacct tgttgaaact cgtagactac
     2821 attccaccgg tattgcttac aggtttgaca gttgctggta aaatgctccc agctatcggt
     2881 tttgcgatga tcttgtcagt gatggctaag aaagagttga ttccctttgt cttgttggga
     2941 tatgtttgtg cagcttatct aaacatccca acaattggta ttgcaattgt aggtactatc
     3001 tttgctttga ttgaatttta taacaagcca aaaacagcgg atcatgtggt agaggaggaa
     3061 gcacacgatg actggatcta acaaattaac aaaacgtgat tatcttaaaa cgtctttgcg
     3121 ggcattcttt tgtcaaaatg gatttaacta tagtaactat caagggttgg gatatgccaa
     3181 tgtgatgtat cctgctttga aaaaacacta tggagaggat caggaaggtt tctaccaagc
     3241 cttggaagaa aactgtgaat tctataatac caacccacac ttcctgcctt ttattaccag
     3301 cttgcatctt gtaatgttgg aaaatggccg tccggcaaaa gaaacacgta gcatcaagat
     3361 ggccttgatg ggaccattgg caggtattgg ggattctctt tctcaattct gtttagctcc
     3421 attgttctca accatcgcag cttcgtttgc tcaagaaggc ttggttgtcg gtccaatctt
     3481 gttcttcctt gcgatgaata cgattttaac agcgattaaa ttgtcaactg gtctgtatgg
     3541 atacaaacta ggaacaactg tgattgataa actaagcgaa cagatggcaa cgatttctcg
     3601 tattgccaat attatcggtg taaccgtaat tgctggtttg gcagcgacat ctgttaagat
     3661 tatggtgccg attacctttg ctgcaggaga agttaaagca gacgctaaac aaagtatcgt
     3721 aagtattcag ggaatgcttg ataaggttgc tccagctctt ctaccagccc tatttacact
     3781 tttagtttac tacttgatca aagaaaagaa atggacaaca tataaactcg ttattttaac
     3841 agttatcatc ggaattatcg gaagctggct taagattata gcttaatgga tacaacattg
     3901 ttttatggaa tagtgattgt cttggcagtg agtccccttt tactgtcaag ctttcattct
     3961 attcgtcagc aaaagttgct tcgcaaacag atggagcaac gacaagagta tttagcttct
     4021 ttaacatctg gtgatgaagt gttgttactg tctggaattc atggaaaaat catttctatc
     4081 aaagatgact tggtctcctt gcagattgca aaaggtgtgg tcatctatgt agaaaaggaa
     4141 agtgtaatgg gaaagacaaa agaactgctt tttaagtagt tctttttctg gtaatagata
     4201 atgaaagaag aaagaagaca attttttgaa agagtcgatg gaaaccaatg tcgtgattat
     4261 atcttgtcgc actgttcaaa agactatgag aaagtcaaga gttcccttga acgcttgatg
     4321 aacaatcgtt ttatgtttga tagtccttgg gatatggagc cttgttcaaa aatccatcaa
     4381 atccagccga tggtatggga tcaagtattt gaagatgatc cagaatgggc ttatatgctc
     4441 aatcgacaag aatatctctt gcagtttatg atagggtatc tggtagaagg agataagagc
     4501 tatattcaaa agtgcaagtt ctttctattt gattggattg agcaggtgag agaattttct
     4561 cctcaatcct tgatgactag aaccttggat acgggtattc gttcctttac ttggttgaaa
     4621 ctactcttgc tcctcttgaa atttgacttg ctagaggaga aagaactaga gaaaattttg
     4681 gtcagtctag aaaagcagat tgactttatg aaaagctact atcgcgccaa gtacaccctt
     4741 agtaactggg ggattttaca aacaattccg atgcttgcta tctatcattt cttttcagat
     4801 aagatggacc tagaagaagc ttaccatttt gcttcagagg agttgaaaca gcaaattgag
     4861 acacagattt taggagatgg aagccagttt gaacagtcga ttctctatca tgtagaggtt
     4921 tataaagcct tgctggattt gtgtctcttg cttccagact tgcaagatag ttaccgagag
     4981 ttgctggaaa agatggcgac ctatattcaa atgatgacag gcttagatgg acggactttg
     5041 gcttttggtg atagcgattc tacagaaacg acagaaatgt tgagcctgtc tgctgtggtt
     5101 ttgaacaagg aagaccttct taacggtctg gatgttaaag ttgatttgct tagcctcttg
     5161 ttcctggggc gagaaaaggt caagcgactg caggaatttg aaaggagagc ttggcagcct
     5221 aagtccatga tctttgaaga ctctggacat gtctgcatta aggatgaaca tcgttatcta
     5281 tttttcaaaa atggtccgct aggaagtgcc catagccata gtgacgagaa tagtttttgc
     5341 ttacagtatc aaggccaacc tattttcata gatgctgggc gttattctta tcgggagata
     5401 tatgaacgtt atctcttaaa gagtgcttgg agtcattcaa cctgcattgt agatgggaaa
     5461 gctccggaaa gaatcacggg atcctgggaa tatgaatact atcctcactc cctgttttgt
     5521 caccataaag aaagggaggg agtgcattat attgaggggg cttattggtc agcagaacct
     5581 gatttgcctt atcttcacaa gagaaaaatc ctcatgttgg tagaggatgt ctggctcttg
     5641 gtagatgaca tcaggtgtca aggtcagcat gaggcgttga ctcagtttat ccttgacaag
     5701 gatgtgacct atcaagatgg gaaaatcaat cagttgagac tatggagtga agttgatttt
     5761 gatttggaag ataccatcat ttctcctaaa tacaatgagc ttgaaagaag tagcaaactc
     5821 accaagcgcc aattctttga gaatcagatg ctggattata ccatcattgc gcatgagagt
     5881 tttgaaatca tccgtcattc tgtctaccag acagatgatc gtgaagtgga aaatgctctg
     5941 gcttttgaag tgaaaaatga cgaaacagac aagctgattc tgttattaag cgaggatatt
     6001 ggtgtaggtg aaaaattgtg cctcgttgac ggaacaaaaa tgcgtggaaa atgtctagta
     6061 tatgataaaa taaatgagag aatgattcgc ttgcagtgct agaaataggc attttgaata
     6121 gtgaatatgt tataataagt attagtagga ggtgttttag attggagaag aaactgacca
     6181 taaaagacat tgcggaaatg gctcagacct cgaaaacaac cgtgtcattt tacctaaacg
     6241 ggaaatatga aaaaatgtcc caagagacac gtgaaaagat tgaaaaagtt attcatgaaa
     6301 caaattacaa accgagcatt gttgcgcgta gcttaaactc caaacgaaca aaattaatcg
     6361 gtgttttgat cggtgatatt accaacagtt tctcaaacca aattgttaag ggaattgagg
     6421 atatcgccag ccagaatggc taccaggtaa tgataggaaa tagtaattac agccaagaga
     6481 gtgaggaccg gtatattgaa agcatgcttc tcttgggagt agacggcttt attattcagc
     6541 cgacctctaa tttccgaaaa tattctcgta tcatcgatga gaaaaagaag aaaatggtct
     6601 tttttgatag tcagctctat gaacaccgga ctagctgggt taaaaccaat aactatgatg
     6661 ccgtttatga catgacccag tcctgtatcg aaaaaggtta tgaacatttt ctcttgatta
     6721 cagcggatac gagtcgtttg agtactcgga ttgagcgggc aagtggtttt gtggatgctt
     6781 taacagatgc taatatgcgt cacgccagtc taaccattga agataagcat acgaatttgg
     6841 aacaaattaa ggaattttta caaaaagaaa tcgatcccga tgaaaaaact ctggtattta
     6901 tccctaactg ttgggcccta cctctagtct ttaccgttat caaagagttg aattataact
     6961 tgccacaagt tgggttgatt ggttttgaca atacggagtg gacttgcttt tcttctccaa
     7021 gtgtttcgac gctggttcag ccctcctttg aggaaggaca acaggctaca aagattttga
     7081 ttgatcagat tgaaggccgc aatcaagaag aaaggcaaca agtcttggat tgtagtgtga
     7141 attggaaaga gtcgactttc taaaatgaag gaaaatgact tgcaatttct gttaagaaat
     7201 aaaataatcc cacctagaac aagctaggtg ggattatttg cctatgaaat gagaaattat
     7261 gggagcaagc tcctaaatca actgtttttg atctacttct ttaactactt gataaaagtt
     7321 atagaagtag gccaaacttg aaatgatggt tacgactagg aatattgaaa atttccattg
     7381 gacagggttg gttaaaagtt gtggaaagga tatgaggaga aagaagaggg ctgcgttgag
     7441 gacaggtatc cgttttgatt gtattttctc aagtccttta ttgagcgcag gaagaaagag
     7501 gagtaggagt agtaaaactg tatgagaaac agctcctgaa ataagggcga agaaaaggaa
     7561 aatactgata aaaacatgaa tgatcagtag tctagctagt gatttcataa ggcacctcct
     7621 aatcctggtc ttttttagct cttgcaatac gaagtgagtc gacaatatgt atcatcactc
     7681 cgaaaaagaa agctcccagt atagttttaa aaatatgttt tgtatttaga agagaactga
     7741 taaaatttgg attttcactt gttagggtat caatgagtgg aattataaaa aatatcactg
     7801 ttccataaat cgaacctgct ttcagaccag gataacgtaa ctgtttcttt tcttttttca
     7861 tgagtttgct ccttttttaa aaatcttcct tccaaaagag actgttgagg tcagtttgga
     7921 ggctgcgggc gagattgaga cagagttcca gagttggatt gtacttgtcg ttttcaatca
     7981 tattgatggt ctgtctcgag acaccgatat ccttggcgag ctcgagctgg gaaatgccca
     8041 gttccttgcg aaattctttc acacgattca tctggtctcc tttctgattt gtgtcgtata
     8101 tatttgactt tattatagtc ttttaaacat aaagtgtcaa gtatttttga catatttttt
     8161 gaagaaatag tagtctcctt gtcctatttg tctgacaagt gcaagctggt cggatttgtg
     8221 gtaaaataga taagatatga caaaagaatt tcatcatgta acggtcttac tccacgaaac
     8281 gattgatatg cttgacgtaa aacctgacgg tatctacgtt gatgcgactt tgggtggagc
     8341 aggccatagc gagtatttat taagtaaatt aagtgaaaaa ggccatctct atgcctttga
     8401 ccaggatcag aatgccattg acaatgcgca aaaacgcttg gcaccttaca ttgagaaggg
     8461 aatggtgacc tttatcaagg acaacttccg tcatttacag gcacgtttgc gcgaagctgg
     8521 tgttcaggaa attgatggaa tttgttatga cttgggagtg tctagtcctc aattagacca
     8581 gcgtgagcgt ggtttttctt ataaaaagga tgcgccactg gacatgcgga tgaatcagga
     8641 tgctagtctg acagcctatg aagtggttaa tcattatgac tatcatgatt tggttcgtat
     8701 tttcttcaaa tacggtgagg ataaattctc taaacagatt gcgcgtaaga ttgagcaagc
     8761 gcgtgaagtg aagccgattg agacaacgac tgagttagca gagattatca agttggtcaa
     8821 acctgccaag gaactcaaga agaaggggca tcctgctaag cagattttcc aggctattcg
     8881 aattgaagtc aatgatgaac tgggagcggc agatgagtcc atccagcagg ctatggatat
     8941 gttggctctg gatggtagaa tttcagtgat tacctttcat tccttagaag accgcttgac
     9001 caagcaattg ttcaaggaag cttcaacagt tgaagttcca aaaggcttgc ctttcatccc
     9061 agatgatctc aagcccaaga tggaattggt gtcccgtaag ccaatcttgc caagtgcgga
     9121 agagttagaa gccaataacc gctcgcactc agccaagttg cgcgtggcca gaaaaattca
     9181 caagtaagag ggaaaaagat ggcagaaaaa atggaaaaaa caggtcaaat actacagatg
     9241 caacttaaac ggttttcgcg tgtggaaaaa gctttttact tttccattgc tgtaaccact
     9301 cttattgtag ccattagtat tatttttatg cagaccaagc tcttgcaagt gcagaatgat
     9361 ttgacaaaaa tcaatgcgca gatagaggaa aagaaaaccg aattggacga tgccaagcaa
     9421 gaggtcaatg aactattacg tgcagaacgt ttgaaagaaa ttgccaattc acacgatttg
     9481 caattaaaca atgaaaatat tagaatagcg gagtaagata tgaagtggac aaaaagagta
     9541 atccgttatg cgaccaaaaa tcggaaatcg ccggctgaaa acagacgcag agttggaaaa
     9601 agtctgagtt tattatctgt ctttgttttt gccatttttt tagtcaattt tgcggtcatt
     9661 attgggacag gcactcgctt tggaacagat ttagcgaagg aagctaagaa ggttcatcaa
     9721 accacccgta cagttcctgc caaacgtggg actatttatg accgaaatgg agtcccgatt
     9781 gctgaggatg caacctccta taatgtctat gcggtcattg atgagaacta taagtcagca
     9841 acgggtaaga ttctttacgt agaaaaaaca caatttaaca aggttgcaga ggtctttcat
     9901 aagtatctgg acatggaaga atcctatgta agagagcaac tctcgcaacc taatctcaag
     9961 caagtttcct ttggagcaaa gggaaatggg attacctatg ccaatatgat gtctatcaaa
    10021 aaagaattgg aagctgcaga ggtcaagggg attgatttta caaccagtcc caatcgtagt
    10081 tacccaaacg gacaatttgc ttctagtttt atcggtctag ctcagctcca tgaaaatgaa
    10141 gatggaagca agagcttgct gggaacctct ggaatggaga gttccttgaa cagtattctt
    10201 gcagggacag acggcattat tacctatgaa aaggatcgtc tgggtaatat tgtacccgga
    10261 acagaacaag tttcccaacg aacgatggac ggtaaggatg tttatacaac catttccagc
    10321 cccctccagt cctttatgga aacccagatg gatgcttttc aagagaaggt aaaaggaaag
    10381 tacatgacag cgactttggt cagtgctaaa acaggggaaa ttctggcaac aacgcaacga
    10441 ccgacctttg atgcagatac aaaagaaggc attacagagg actttgtttg gcgtgatatc
    10501 ctttaccaaa gtaactatga gccaggttcc actatgaaag tgatgatgtt ggctgctgct
    10561 attgataata atacctttcc aggaggagaa gtctttaata gtagtgagtt aaaaattgca
    10621 gatgccacga ttcgagattg ggacgttaat gaaggattga ctggtggcag aatgatgact
    10681 ttttctcaag gttttgcaca ctcaagtaac gttgggatga ctctccttga gcaaaagatg
    10741 ggagatgcta cctggcttga ttatcttaat cgttttaaat ttggagttcc gacccgtttc
    10801 ggtttgacgg atgagtatgc tggtcagctt cctgcggata atattgtcaa cattgcgcaa
    10861 agctcatttg gacaagggat ttcagtgacc cagacacaaa tgattcgtgc ctttacagct
    10921 attgctaatg acggtgtcat gctggagcct aaatttatta gtgccattta tgatccaaat
    10981 gatcaaactg ctcggaaatc tcaaaaagaa attgtgggaa atcctgtttc taaagatgca
    11041 gctagtctaa ctcggactaa catggttttg gtagggacgg atccggttta tggaaccatg
    11101 tataaccaca gcacaggcaa gccaactgta actgttcctg ggcaaaatgt agccctcaag
    11161 tctggtacgg ctcagattgc tgacgagaaa aatggtggtt atctagtcgg ggtaaccgac
    11221 tatattttct cggctgtatc gatgagtccg gctgaaaatc ctgattttat cttgtatgtg
    11281 acggtccaac aacctgaaca ttattcaggt attcagttgg gagaatttgc caatcctatc
    11341 ttggagcggg cttcagctat gaaagactct ctcaatcttc aaacaacagc taaagctttg
    11401 gagcaagtaa gtcaacaaag tccttatcct atgcctagtg tcaaggatat ttcacctggt
    11461 gatttagcag aagaattgcg tcgcaatctt gtacaaccca tcgttgtggg aacaggaacg
    11521 aagattaaaa acagttctgc tgaagaaggg aagaatcttg ccccgaacca gcaagtcctt
    11581 atcttatctg ataaagcaga ggaagttcca gatatgtatg gttggacaaa ggagactgct
    11641 gagacctttg ctaagtggct caatatagaa cttgaatttc aaggttcggg ctctactgtg
    11701 cagaagcaag atgttcgtgc taacacagct atcaaggaca ttaaaaaaat tacattaact
    11761 ttaggagact aatatgttta tttccatcag tgctggaatt gtgacatttt tactaacttt
    11821 agtaggaatt ccggccttta tccaatttta tagaaaggcg caaattacag gccagcagat
    11881 gcatgaagat gtcaaacagc atcaggcaaa agctgggact cctacaatgg gaggtttggt
    11941 tttcttgatt acttctgttt tggttgcttt ctttttcgcc ctatttagta gccaattcag
    12001 caataatgtg ggaatgattt tgttcatctt ggtcttgtat ggcttggtcg gatttttaga
    12061 tgactttctc aaggtctttc gtaaaatcaa tgaggggctt aatcctaagc aaaaattagc
    12121 tcttcagctt ctaggtggaa ttatcttcta tcttttctat gagcgtgggg gcgatatcct
    12181 gtctgtcttt ggttatccag ttcatttggg atttttctat attttcttcg ctcttttctg
    12241 gctagtcggt ttttcaaacg cagtaaactt gacagacggt gttgacggtt tagctagtat
    12301 ttccgttgtg attagtttgt ctgcctatgg agttattgcc tatgtgcaag gtcagatgga
    12361 tattcttcta gtgattcttg ccatgattgg tggtttgctc ggtttcttca tctttaacca
    12421 taagcctgcc aaggtcttta tgggtgatgt gggaagtttg gccctaggtg ggatgctggc
    12481 agctatctct atggctctcc accaggaatg gactctcttg attatcggaa ttgtgtatgt
    12541 ttttgaaaca acttctgtta tgatgcaagt cagttatttc aaactgacag gtggtaaacg
    12601 tattttccgt atgacgcctg tacatcacca ttttgagctt gggggattgt ctggtaaagg
    12661 aaatccttgg agcgagtgga aggttgactt cttcttttgg ggagtgggac ttctagcaag
    12721 tctcctgacc ctcgcaattt tatatttgat gtaagaatgg caccctgatg tttcagggtg
    12781 tttttgtgtt taaatacaca atgaaaatca aagaacaaac tagaaagcta actttaggct
    12841 gctcaaaata tagtagattg aaactagaat agtacacatc tacttctaaa acatttttag
    12901 aaatcgattt gactgtcctg aacgatttgg cctgttctta tttcatttca ctatacagag
    12961 ttttgagatg gttgatagaa ctgacgaagt cagctcaaaa cacggttttg aggttgtaga
    13021 caaggcgaag ctgatgtggt ttgaagagat tttcgaagag tgtaaaaaat attggtcagt
    13081 taaagtcaaa atccttgacc ttttctgacc aatgtagtat attatgaacg taaggtaaat
    13141 gaaagcctta ctagaacact tatttaaagt aaaatagaaa gaggtgggtc tatgtttcat
    13201 ctagaaatct tcagaagtaa agatggtcta ctcctgcttg aaaaagaaaa accagaaata
    13261 gtacgtaggg tagcggttta gctagtctaa attttttaaa acaatggtca aagatagtca
    13321 atatcagtaa tcataactaa gtaaacaaaa agaggtaaag aatatgaata acaactttaa
    13381 taattttaat aacatggatg atttatttaa ccaattgatg ggtggtatgc gaggatatag
    13441 ttctgaaaat cgccgttact taattaatgg acgcgaagtc acacctgagg aatttgctca
    13501 ctatcgtgcg actggtcaat taccaggaaa tgcagaaact gatgtgcaaa tgccacaaca
    13561 ggcatcaggt atgaaacaag acggtgtcct tgcaaaacta ggtcgaaact tgacagcaga
    13621 agcgcgtgag ggtaagttgg atcctgttat cggacgaaac aaggaaattc aagaaacatc
    13681 tgaaatcctc tcacgccgca ccaagaacaa tcctgttttg gtcggagatg caggtgttgg
    13741 taagacagca gttgtcgaag atctagcgca agccattgtg aacggagatg ttcctgctgc
    13801 tatcaagaac aaggaaatta tttctattga tatctcaggt cttgaggctg gtactcaata
    13861 ccgtggtagc tttgaagaaa atgtccaaaa cttagtcaat gaagtgaaag aagcagggaa
    13921 tattatcctc ttctttgatg aaattcacca aattcttggt gctggtagca ctggtggaga
    13981 cagtggttct aaagggcttg cggatattct caagccagct ctctctcgtg gagaattgac
    14041 agtgattggg gcaacaactc aagacgaata ccgtaacacc atcttgaaga atgctgctct
    14101 tgctcgtcgt ttcaacgaag tgaaggtcaa tgctccttca gcagagaata cttttaaaat
    14161 tcttcaaggc attcgtgacc tctatcaaca acaccacaat gtcatcttgc cagacgaagt
    14221 cttgaaagca gcggtggatt attctgttca atacattcct caacgtagct tgccagataa
    14281 ggctattgac cttgtcgatg taacggctgc tcacttggcg gctcaacatc cagtaacaga
    14341 tgtgcatgct gttgaacgag aaatcgaaac ggaaaaagac aagcaagaaa aagcagttga
    14401 agcagaagat tttgaagcag ctctaaacta taaaacacgc attgcagaat tggaaaagaa
    14461 aatcgaaaac cacacagaag atatgaaagt gactgcaagt gtcaacgatg tggctgaatc
    14521 tgtggaacga atgacaggta tcccagtatc gcaaatggga gcttcagata tcgaacgttt
    14581 gaaagatatg gctcatcgct tgcaagacaa ggtgattggt caagataagg ccgtagaagc
    14641 tgtagctcgc gctatccgtc gtaaccgtgc tggttttgat gaaggaaatc gcccaatcgg
    14701 cagcttcctc tttgtagggt ctactggggt tggtaagacg gagcttgcta agcaattggc
    14761 actcgatatg tttggaaccc aggatgcgat tatccgtttg gatatgtctg aatacagtga
    14821 ccgcacagct gtttctaagc taattggtac aacagcaggc tatgtgggtt atgatgacaa
    14881 tagcaatacc ttaacagaac gtgttcgtcg caatccatac tctatcattc tcttggatga
    14941 aattgaaaag gctgatcctc aagttattac ccttctcctc caagttctag atgatggtcg
    15001 tttgacagat ggtcaaggaa atacagtaaa cttcaagaac actgtcatta ttgcgacctc
    15061 aaatgctgga tttggctatg aagccaactt gacagaagat gcggataaac cagaattgat
    15121 ggaccgtttg aaacccttct tccgtccaga attcctcaac cgctttaatg cagtcatcga
    15181 gttctcacaa ttgactaagg aagacctttc taagattgta gatttgatgt tggctgaagt
    15241 taaccaaacc ttggctaaga aagacattga cttggtagtc agtcaagcgg ctaaagatta
    15301 tatcacagaa gaaggttacg acgaagtcat gggggttcgt cctctccgtc gcgtggttga
    15361 acaagaaatt cgtgataagg tgacagactt ccacttggat catttagata ctaaacatct
    15421 ggaagcagat atggaagatg gcgttttggt tattcgtgag aaagcctaag acagaatttt
    15481 gaggataaaa aagaaggagc cagctgaaaa aactggttcc ttttgaggta cgacgggcat
    15541 gtcgtatagt aggttgaaac tagaatagta cacatctact tctaaaacat ttttagaaat
    15601 cgatttgact gtcctgatcg atttgtcctg ttcttatttc attttactat atatctgagg
    15661 tgtaagtcct cggtgggcac ctgttaccgg tgaacccaat agcgattccc aagcctgact
    15721 atcgtgaggt agcggattaa aacggtctgg ggatagaccg ttttaagtct gacgctggaa
    15781 ataagaatcg tcagaggaag ggatagcgaa ctcgtggctc tacgaacagg aacgtgatag
    15841 taaggcgtat atagcggata agggggcctc aaactctaaa gtccaaaaag gtagtcgtaa
    15901 cctatatgcg taaatcacga gagcaactga atttgtccat tcgaggatgg ataaactatt
    15961 tttcattggg aaatatgaaa aatatagtca ctagcataga tgagcgcttg cgtactcgcc
    16021 tactcgccta cgagtgatta tctggaagca atggaagaag aaacctagac gattatggag
    16081 attgcttaag ttaggggttc ctaaatggat agcagataag gtatctggct ggggtgacca
    16141 ctatcaatta gtatctcaga agtcggtact taaacgtgct atatcaaaac cagtccttga
    16201 gaaacgtgga ctggtttcgt gtttggatta ttaccttgaa cgacatacgt taaaagttag
    16261 ttgaaccgcc gtatgccgaa cggcacgtac ggtggtgtga gaggggctag agattatccc
    16321 ctactcgatt ttaaatcaca tgacgttcaa aggcatcatc tgaaatccct tgttccaaga
    16381 tgagttttgc ccattcttta gcagagaaga ggctgtggtc cttgtagttt ccgcaagatt
    16441 cgatggttgt ccctgggaca tcttcccaag tagtagtttc agcgatttcc ttgagcgaat
    16501 ccttgataac agctgcgatt ttagcactgg tgtgacgtcc ccacataatc atgtggaagc
    16561 ctgtgcggca accaaatggt gaacaatcaa tcatgccgtc aatgcgggta cggatgagtt
    16621 tggctaagag gtgctcgata gtgtgaaggc cggcagtagg gatagagtct tcgtttggtt
    16681 gcaccaagcg aatatcataa ttggagatga tgtctccttt tggtcctgtt tcttccccaa
    16741 tcaagcgaac atagggtgct ttgacaatgg tgtggtcaag ttcaaaactt tcgacaataa
    16801 cttcttttga catggtaaat cctttcagtt ttcttctctc attatatcat aaaggttgtt
    16861 cctgagacag agagaaaacc tctccgaggc tagagaggtt gaaatcttta cttacgatat
    16921 aagcggtcgt attggtagta tgggtcaaag gttacgttga tacccagttt acgaaggaca
    16981 ttctggtctt catcagtcaa gatgatggtt gagtgggctt cgcttccttt gaggttgccg
    17041 agttcttcca tagcgcgggc agcatcagga ttttctgtag ctgtgatagc aagtgcaatc
    17101 aggatttcat ttgaatgaag gcgtggattg cggctaccga gatgatcgat tttaagacct
    17161 tggattggct taacaacttc aggctcgatt agttttactt ctttagcgat gtcagctgat
    17221 tttttgatgg cgttgatcaa ggcagcggct gtaggcccaa agagttctga gttcttacca
    17281 gtgacgattt ccccatttgg caattcaaag gctagggctg gtccaccagt ttcttctgct
    17341 ttttggcgcg caacgacagc aaccttacgg tctgcaggtg tgataccgag gtcgttcatg
    17401 agcaactcaa ttttcttgac ggcagcttcg ccaacttttt cagctttgaa gtcaagaact
    17461 gtttgatagt aacggcggat gatttcttgt ttagaagctt cgacagcggc ctcgtcatct
    17521 gtaatagcga aaccaaccat gttgacaccc atatctgtcg gtgaagcgta tggtgatttt
    17581 ccgagaatac gttccaacat gcgcttgagc actgggaaga tttcgatatc acggttgtag
    17641 ttgacagtgg tttctccata ggtttgaaga tggaaggggt caatcatgtt gacatcatca
    17701 aggtcagctg tggcagcttc ataagccaag ttaactggat gatgaagggg aagattccaa
    17761 acagggaagg tttcaaattt agcgtagcca gacttgatgc cattgatttg gtcgtggtac
    17821 atattggaca tacacgttgc caattttcca gaaccgggtc caggagcggt tacgacaatc
    17881 aagttgcgac tggttttgat gtagtcgttt ttgcccatgc cttctgagga aatgatgtga
    17941 tccatatccg tcggatagcc tttgattgga taatgaagat aagaatcaat tccgtttttc
    18001 tcaagttggt tgcggaaggc atctgcagcg ggttggccag cgtattgtgt aatgacaacg
    18061 gaaccaacaa aaatccctaa ttcattgaat ttgtcaatca aacgaagaac ttcttggtca
    18121 taagaaatgc ctaagtcgcc acgtgctttg gaatgttcaa tgttactagc attaatggca
    18181 atcacaacct caacctgctc tttcaattct tgcaagagct tgattttgtt gtcaggttca
    18241 taaccaggaa ggacacgagc agcgtggaaa tcttctaaca ttttaccgcc aaactctaag
    18301 tagagcttgc cgtcaaattg gttaatgcgc tccaaaatat ggtcgcgttg taaattcaaa
    18361 tactgttcag aactaaaagc ttgttttttc atttttttac ctctggactc tattataata
    18421 aaaaattgga agttaggaaa ctacggagct aaaaaagaaa ttaaaaagat taagcaaacg
    18481 cttgcacaaa attttaaaaa gtgctatcat agactataga ttattaaaat aatgaggtaa
    18541 acagatgcaa gaaaaatggt ggcataatgc cgtagtctat caagtctatc caaagagttt
    18601 tatggatagt aatggagatg gagttggtga tttgccaggt attaccagta agttggacta
    18661 tctagccaag ttaggaatca cagcgatttg gctttctccc gtttatgaca gccctatgga
    18721 tgataatggc tacgatattg ctgattatca agcgattgcg gctatttttg gaaccatgga
    18781 ggacatggat cagctgattg cagaagctaa gaagcgtgat atccgtatca tcatggactt
    18841 ggtggtcaat catacctcgg atgagcatgc ctggtttgta gaggcctgtg aaaattctaa
    18901 tagccctgag cgagactact atatctggcg cgatgaaccc aatgacctag attctatctt
    18961 tagtgggtct gcttgggaat acgatgaaaa gtcaggtcaa tactatctcc actttttcag
    19021 caagaaacag ccggatctca actgggaaaa tgaaaaactt cgccagaaaa tttatgagat
    19081 gatgaacttc tggattgata aaggtattgg tggtttccgt atggatgtta ttgacatgat
    19141 tggcaaaatt cctgacgaga aggtagtcaa taatggtcct atgctccatc cctatctcaa
    19201 ggaaatgaat caggcgacct ttggagataa ggatctcttg acagtagggg agacttgggg
    19261 agcaacgcca gagattgcca ggctctactc tgatccaaag gggcaagaat tgtctatggt
    19321 cttccagttt gaacatatcg gtcttcagta tcaggaaggt cagcctaaat ggcactatca
    19381 aaaagagctg aatatcgcta agttaaaaga aatcttcaac aaatggcaga cagagttagg
    19441 agttgaggac ggctggaatt ccctcttctg gaacaaccat gacctccctc gtattgtctc
    19501 aatctgggga aatgaccaag aataccgcga aaaatctgcc aaagcctttg caatcttact
    19561 tcatctcatg agaggaactc cttatatcta ccaaggtgag gagattggga tgaccaacta
    19621 tccgtttgaa acactggatc aagtagaaga tattgaatcc ctcaactatg cgcgtgaggc
    19681 tcttgaaaaa ggtgttccga ttgaagaaat catggacagt atccgtgtta ttggacgtga
    19741 caatgcccgt acccctatgc aatgggacga gagcaaaaac gctggtttct caacaggtca
    19801 accttggttg gcggttaatc caaattacaa gatgatcaat gtccaagaag cgctggcaaa
    19861 tccagattct attttctata cctatcaaaa actggtccaa attcgcaagg agaatagctg
    19921 gctaattcga gctgactttg aattgcttga tacggctgat aaggtctttg cttatatacg
    19981 taaggatgga gaccgtcgct tcctagttgt ggctaacttg tccaatgaag agcaagactt
    20041 gacagtggaa ggaaaagtca aatctgtctt gattgaaaac actgcggcta aagaagtctt
    20101 tgaaaaacaa atcttagttc catgggatgc tttctgtgtg gaattactat aaatattttt
    20161 tgcagaaaaa tttaaaattg aaatcgtata aaaacaaggg aggactgtat aaaagacaga
    20221 aatcctttgt tttttataac caaggtttat aaactttcat tatcgaaatt caattaactt
    20281 tacaaattcc cactattaag gagaaagaaa atgaacataa agaagcgtgt ccttagtgca
    20341 ggtctgactt ttgcatctgc tttgctttta gctgcttgcg accaatcagg ttcagataca
    20401 aaaacttact catcaacctt tagtggaaat ccaactacat ttaattacct gttagactat
    20461 tacgctgata atatagtcaa ttgaaacaag agcaggacaa aagagcctcg taaaaggtat
    20521 tgcaacttgg taataccttt tacgaggctt tttgatatga gcccatgttt tctcaatagg
    20581 attgtactca ggtgagtagg gaggaagaag gtaaaagttt atgcccaaac tcttcgcata
    20641 aaagttctag cttccccatt ctatggaatc ttgcattatc cataataata accgatggtg
    20701 tggttaatgt tggtaagaaa aacttctgaa accaagcttc aaaaaagtcg ctcgtcatca
    20761 tctcttcgta agtcattgga gtgattaact caccatttgt tagacctgca accaaagaaa
    20821 tcctctgata tcttcttcca gatactttgc ctcttattaa ctgacctttt aatgagcgac
    20881 catattctcg ataaaaataa gtatcgaatc ctgtttcgtc aatctaaaca ggtgctaggt
    20941 gctttaatct attaaaattc ttaagaaata aggctacttt ttctgggtct tgttcatagt
    21001 aggtgtggtt ctttttttcg agtgtagccc atagctttga gcgcatag
//
LOCUS       DBEJAU010000037        20587 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC323 isolate 683620
            SAMN38261939-rid24807223.denovo.037, whole genome shotgun sequence.
ACCESSION   DBEJAU010000037 DBEJAU010000000
VERSION     DBEJAU010000037.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261939
            Sequence Read Archive: SRR26833919
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 20587)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20587)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576303.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576303.1
            Genome Coverage       :: 154x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/19/2025 01:05:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,121
            CDSs (total)                      :: 2,078
            Genes (coding)                    :: 1,943
            CDSs (with protein)               :: 1,943
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 36
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 72 of 135
            Pseudo Genes (incomplete)         :: 63 of 135
            Pseudo Genes (internal stop)      :: 51 of 135
            Pseudo Genes (multiple problems)  :: 46 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20587
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261939-rid24807223.denovo.037"
                     /strain="GPSC323"
                     /isolate="683620"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            complement(372..521)
                     /locus_tag="ACL29Z_001452"
     CDS             complement(372..521)
                     /locus_tag="ACL29Z_001452"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000410533.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell envelope"
                     /protein_id="HGR0069742.1"
                     /translation="MEKFNFKNNIGQENKLLQIEIYKFTNFCKLQNYTSVNIFSKDIF
                     EAIVN"
     gene            486..605
                     /locus_tag="ACL29Z_001453"
     CDS             486..605
                     /locus_tag="ACL29Z_001453"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001808898.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine synthetase"
                     /protein_id="HGR0069743.1"
                     /translation="MPDIVFEIEFFHSDSLIFFYTSDDKSNSQKSQEDFSKNK"
     gene            complement(701..2047)
                     /gene="glnA"
                     /locus_tag="ACL29Z_001454"
     CDS             complement(701..2047)
                     /gene="glnA"
                     /locus_tag="ACL29Z_001454"
                     /EC_number="6.3.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008808235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004356 - glutamine synthetase activity
                     [Evidence IEA];
                     GO_process: GO:0006542 - glutamine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type I glutamate--ammonia ligase"
                     /protein_id="HGR0069744.1"
                     /translation="MPITAADIRREVKEKNVTFIRLMFSDILGTMKNVEIPATDEQLD
                     KVLSNKVMFDGSSIEGFVRINESDMYLYPDLDTWTVFPWGDENGSVAGLICDVYTTEG
                     EPFAGDPRGNLKRALRHMEEVGFKSFNLGPEPEFFLFKLDENGDPTLEVNDKGGYFDL
                     APTDLADNTRREIVNVLTKMGFEVEASHHEVAVGQHEIDFKYDEVLRACDKIQIFKLV
                     VKTIARKHGLYATFMAKPKFGIAGSGMHCNMSLFDTEGNNAFFDPNDPKGMQLSETAY
                     HFLGGLIKHAYNYTAIMNPTVNSYKRLVPGYEAPVYIAWAGRNRSPLVRVPASRGMGT
                     RLELRSVDPMANPYVAMAVLLEVGLYGIENKIEAPAPIEENIYIMTAEERKEAGITDL
                     PSTLHNALKALTEDEVVKAALGDHIYTSFLEAKRIEWASYATFVSQWEIDNYLDLY"
     gene            complement(2084..2440)
                     /gene="glnR"
                     /locus_tag="ACL29Z_001455"
     CDS             complement(2084..2440)
                     /gene="glnR"
                     /locus_tag="ACL29Z_001455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000659547.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor GlnR"
                     /protein_id="HGR0069745.1"
                     /translation="MKEKEFRRNMAVFPIGSVMKLTDLSARQIRYYEDQELIKPDRNE
                     GNRRMYSLNDMDRLLEIKDYISEGYNIAAIKKKYAEREAKSKKAVSQTEVRRALHNEL
                     LQQGRFASVQSPFGRG"
     gene            complement(2517..3044)
                     /locus_tag="ACL29Z_001456"
     CDS             complement(2517..3044)
                     /locus_tag="ACL29Z_001456"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000119911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aromatic acid exporter family protein"
                     /protein_id="HGR0069746.1"
                     /translation="MSYFKKYKFDKSQFKLGMRTFKTGIAVFLVLLIFCFFGWKGLQI
                     GALTAVFSLRESFDESVHFGTSRILGNSIGGLYALVFFLLNTFFHEAFWVTLVVVPIC
                     TMLTIMTNVAMNNKAGVIGGVAAMLIITLSIPSGETISYVFVRVSETFMGVFVAIIVN
                     YDIDRIRLFLEKKEK"
     gene            complement(3180..4376)
                     /gene="pgk"
                     /locus_tag="ACL29Z_001457"
     CDS             complement(3180..4376)
                     /gene="pgk"
                     /locus_tag="ACL29Z_001457"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001096748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004618 - phosphoglycerate kinase activity
                     [Evidence IEA];
                     GO_process: GO:0006096 - glycolytic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglycerate kinase"
                     /protein_id="HGR0069747.1"
                     /translation="MAKLTVKDVDLKGKKVLVRVDFNVPLKDGVITNDNRITAALPTI
                     KYIIEQGGRAILFSHLGRVKEEADKAGKSLAPVAADLAAKLGQDVVFPGVTRGAELEA
                     AINALEDGQVLLVENTRYEDVDGKKESKNDPELGKYWASLGDGIFVNDAFGTAHRAHA
                     SNVGISANVEKAVAGFLLENEIAYIQEAVETPERPFVAILGGSKVSDKIGVIENLLEK
                     ADKVLIGGGMTYTFYKAQGIEIGNSLVEEDKLDVAKALLEKANGKLILPVDSKEANAF
                     AGYTEVRDTEGEAVSEGFLGLDIGPKSIAKFDEALTGAKTVVWNGPMGVFENPDFQAG
                     TIGVMDAIVKQPGVKSIIGGGDSAAAAINLGRADKFSWISTGGGASMELLEGKVLPGL
                     AALTEK"
     gene            complement(4466..9445)
                     /locus_tag="ACL29Z_001458"
     CDS             complement(4466..9445)
                     /locus_tag="ACL29Z_001458"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000795197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacterial Ig-like domain-containing protein"
                     /protein_id="HGR0069748.1"
                     /translation="MKNPFFERRCRYSIRKLSVGACSLMIGAVLFAGPALAEETAVPE
                     NSGANTELVSGESEHSTNEADKQNEGEHARENKLEKAEGVAIASETASPASNEAATTE
                     TAEAASAAKPEEKASEVVAETPSAEAKPKSDKETEAKPEATNQGDESKPAAEANKTEK
                     EVQPDVPKNTEKTLKPKEIKFNSWEELLKWEPGAREDDAINRGSVVLASRRTGHLVNE
                     KASKEAKVQALSNTNSKAKDHASVGGEEFKAYAFDYWQYLDSMVFWEGLVPTPDVIDA
                     GHRNGVPVYGTLFFNWSNSIADQERFAEALKQDADGSFPIARKLVDMAKYYGYDGYFI
                     NQETTGDLVKPLGEKMRQFMLYSKEYAAKVNHPIKYSWYDAMTYNYGRYHQDGLGEYN
                     YQFMQPEGDKVPADNFFANFNWDKAKNDYTIATANWIGRNPYDVFAGLELQQGGSYKT
                     KVKWNDILDENGKLRLSLGLFAPDTITSLGKTGEDYHKNEDIFFTGYQGDPTGQKPGD
                     KDWYGIANLVADRTPAVGNTFTTSFNTGHGKKWFVDGKVSKDSEWNYRSVSGVLPTWR
                     WWQTSTGEKLRAEYDFTDAYNGGNSLKFSGDVAGKTDQDVRLYSTKLEVTEKTKLRVA
                     HKGGKGSKVYMAFSTTPDYKFDDADAWKELTLSDNWTNEEFDLSSLAGKTIYAVKLFF
                     EHEGAVKDYQFNLGQLTISDNHQEPQSPTSFSVVKQSLKNAQEAEAVVQFKGNKDADF
                     YEVYEKDGDSWKLLTGSSSTTIYLPKVSRSASAQGTTQELKVVAVGKNGVRSEAATTT
                     FDWGMTVKDTSLPKPLAENIVPGATVIDSTFPKTEGGEGIEGMLNGTITSLSDKWSSA
                     QLSGSVDIRLTKPRTVVRWVMDHAGAGGESVNDGLMNTKDFDLYYKDADGEWKLAKEV
                     RGNKAHVTDITLDKPITAQDWRLNVVTSDNGTPWKAIRIYNWKMYEKLDTESVNIPMA
                     KAAARSLGNNKVQVGFADVPAGATITVYDNPNSQTPLATLKSEVGGDLASAPLDLTNQ
                     SGLLYYRTQLPGKEISNVLAVSVPKDDRRIKSVSLETGPKKTSYAEGEDLDLRGGVLR
                     VQYEGGTEDELIRLTHAGVSVSGFDTHHKGEQNLTLQYLGQPVNANLSVTVTGQDEAS
                     PKTILGIEVSQEPKKDYLVGDSLDLSEGRFAVAYSNDTMEEHSFTDEGVEISGYDAQK
                     TGRQTLTLHYQGHEVSFDVLVSPKAALNDEYLKQKLAEVEAAKNKVVYNFASSEVKEA
                     FLKAIEAAEQVLKDHETSTQDQVNDRLNKLTEAHKALNGQEKFKEEKTEFDRLTGEVQ
                     ELLAAKPNHPSGSALAPLLEKNKALVEKVDLSPEELATAKQSLKDLVALLKEDKPAVF
                     SDSKTGVEVHFSNKEKTVIKGLKVERVQASAEEKKYFAGEDAHVFEIEGLDEKGQDVD
                     LSYASIVKIPIEKDKKVKKVFFLPEGKEAVELAFEQTDSHVIFTAPHFTHYAFVYESA
                     EKPQPAKPAPQNKVLPKPTYQPASDQQKAPKLEVQEEKVAFHRQEHENAEMLVGEQRV
                     IIQGRDGLLRHVFEVDEKGQRRLRSTEVIQEAIPEIVEIGTKVKTVPAVVATQEKPAQ
                     NTAVKSEEASKQLPNTGTADANEALIAGLASLGLASLALTLRRKREDKD"
     gene            9738..11369
                     /locus_tag="ACL29Z_001459"
     CDS             9738..11369
                     /locus_tag="ACL29Z_001459"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004251733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0005436 - sodium:phosphate symporter
                     activity [Evidence IEA];
                     GO_process: GO:0044341 - sodium-dependent phosphate
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Na/Pi cotransporter family protein"
                     /protein_id="HGR0069749.1"
                     /translation="MSINWQEILFHFLGGLGLFLYSIKTMGDGLQQAAGDRLRFYIDK
                     YTSNPFFGVLVGIGMTALIQSSSGVTVITVGLVSASLLTLRQAIGIVMGANIGTTVTS
                     FLIGFKLGNYALPMLFIGAVCLFFTKNRTVNNIGRILFGVGGIFFALNLMSGAMAPLK
                     DLQVFKDYMIELSKNPVLGVFVGTGLTLLIQASSATIGILQNLYAGNLIDLQGALPVL
                     FGDNIGTTITAIIASLGANIAAKRVAGAHVAFNVIGTVVCVIFLVPFTVLIHWFEATL
                     NLAPEMTIAFAHGTFNITNTIVQFPFIGALAYFVTKIIPGEDEVVKYEPLYLDEHFIK
                     QAPSIALGNAKKELLHLGNYAAKAFDLSYKYIIDLDEKVAEKGHKTEEAINTIDEQLT
                     RYLIALSSEALSQKESEVLTNILDSSRDLERIGDHTEALLNLTDYLQRKNVEFSDAAL
                     KELEEVYRQTSDFIKDALDSVENNDIEKARSLVERHEAINKIERVLRKTHIKRLNKGE
                     CSTQAGVNFIDIISHYTRVSDHAMNLAEKVFAEQI"
     gene            complement(11928..13535)
                     /locus_tag="ACL29Z_001460"
     CDS             complement(11928..13535)
                     /locus_tag="ACL29Z_001460"
                     /EC_number="6.3.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000105234.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003883 - CTP synthase activity [Evidence
                     IEA];
                     GO_process: GO:0006221 - pyrimidine nucleotide
                     biosynthetic process [Evidence IEA];
                     GO_process: GO:0006241 - CTP biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="CTP synthase"
                     /protein_id="HGR0069750.1"
                     /translation="MSTKYIFVTGGVVSSIGKGIVAASLGRLLKNRGLKVTIQKFDPY
                     INIDPGTMSPYQHGEVFVTDDGAETDLDLGHYERFIDINLNKYSNVTTGKIYSEVLRK
                     ERRGEYLGATVQVIPHITDALKEKIKRAALTTDSDVIITEVGGTVGDIESLPFLEALR
                     QMKADVGADNVMYIHTTLLPYLKAAGEMKTKPTQHSVKELRGLGIQPNMLVIRTEEPA
                     GQGIKNKLAQFCDVAPEAVIESLDVEHLYQIPLNLQAQGMDQIVCDHLKLDAPAADMT
                     EWSAMVDKVMNLKKQVKISLVGKYVELQDAYISVVEALKHSGYVNDVEVKINWVNAND
                     VTAENVAELLSDADGIIVPGGFGQRGTEGKIQAIRYARENDVPMLGVCLGMQLTCIEF
                     ARHVLGLEGANSAELAPETKYPIIDIMRDQIDIEDMGGTLRLGLYPSKLKRGSKAAAA
                     YHNQEVVQRRHRHRYEFNNAFREQFEAAGFVFSGVSPDNRLVEIVEIPENKFFVACQY
                     HPELSSRPNRPEELYTAFVTAAVENSN"
     gene            complement(13925..14512)
                     /gene="rpoE"
                     /locus_tag="ACL29Z_001461"
     CDS             complement(13925..14512)
                     /gene="rpoE"
                     /locus_tag="ACL29Z_001461"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000418402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003899 - DNA-directed 5'-3' RNA
                     polymerase activity [Evidence IEA];
                     GO_process: GO:0006351 - DNA-templated transcription
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit delta"
                     /protein_id="HGR0069751.1"
                     /translation="MELEVFAGQEKSELSMIEVARAILELRGRDHEMHFSDLVNEIQN
                     YLGTSNSDIREALPLFYTELNFDGSFISLGDNKWGLRSWYGVDEIDEEIIALEENDDD
                     EVAPKAKKKRVNAFMDGDSDAIDYNADDPEDEDAYEADPALSYDDENPDDEKNEVEAY
                     DAEINEIAPDDLGEDVDLNEDDDEFSDDDAETSEE"
     gene            complement(14640..15089)
                     /locus_tag="ACL29Z_001462"
     CDS             complement(14640..15089)
                     /locus_tag="ACL29Z_001462"
                     /EC_number="2.3.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000333655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0016746 - acyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HGR0069752.1"
                     /translation="MCFVPYYKVNHCEEAFAWYQDVNLVYLVDGVKLPYSQATLEAMY
                     SYLDRHGELFWIEVKEKGEWFPIGDITLSQDNLPIVIGNSAYQHRGLGKKILSALIEL
                     ARVKGWKELRVKEIYTYNHASRRCFKSLGFVENGATEKGMSFILELV"
     gene            complement(15094..15483)
                     /locus_tag="ACL29Z_001463"
     CDS             complement(15094..15483)
                     /locus_tag="ACL29Z_001463"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000867286.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromosome partitioning protein ParB"
                     /protein_id="HGR0069753.1"
                     /translation="MKVNIADLHPTQLYLSEKKLQDIQMLYQSAETIQVDPISILAFG
                     DCLLITDGHHRAYQTLLADRDTISAEWDRDGGDELYHLYAQACEERKIYSVFDLEDRI
                     LAQDGYEAKWYNWCDGFNQAATLLLKR"
     gene            complement(15511..16161)
                     /locus_tag="ACL29Z_001464"
     CDS             complement(15511..16161)
                     /locus_tag="ACL29Z_001464"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466738.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatase PAP2 family protein"
                     /protein_id="HGR0069754.1"
                     /translation="MRDKQTFLMKGSFALLLFVILGYMVKFYPETLVNFDQSIQTAIR
                     GDLPDYLTILFRALTRLIDIPVIITWVVITAFVFYRKRWKIESFFMLGNLALVGLLIV
                     TFKNIYQRPRPDILHLVEEKGFSFPSGHSLAVTLMVGTLIVILSQRIKDPVWRKIVQI
                     VLGLYLVSVLVSRVYLGVHYPSDVLASLCVGLGVLFIEFPFYDKLRFQWRFKGKQK"
     gene            complement(16151..16714)
                     /locus_tag="ACL29Z_001465"
     CDS             complement(16151..16714)
                     /locus_tag="ACL29Z_001465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HGR0069755.1"
                     /translation="MTNTRRLSTIAILSAISFVLMYFDFPLLPAASFLKIEFSILPVL
                     VGLVVMDLPAALGVLLLRSLLKLLLNSQGVNTYIGLPMNIVALGVFVIVFALIWKKER
                     TTLRFLLGSLAGTIGLTLVMLVLNYVYAVPLYAKFANFDIGKILGLSNYLMTMVLPFN
                     LIEGVIFSVSFWLLYVLLKPTLKHYER"
     regulatory      complement(16879..17113)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00050"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="FMN riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="flavin mononucleotide"
                     /db_xref="RFAM:RF00050"
     gene            complement(17167..17670)
                     /locus_tag="ACL29Z_001466"
     CDS             complement(17167..17670)
                     /locus_tag="ACL29Z_001466"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000181367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (cytidine(34)-2'-O)-methyltransferase"
                     /protein_id="HGR0069756.1"
                     /translation="MTNHIVLFEPQIPQNTGNIARTCAATNSPLHIIKPMGFPIDDRK
                     MKRAGLDYWDKLEIYFYESLEDFISQMKGKLYLISKFAEKIYSEVDLSTDEDHYFLFG
                     REDKGLPEDFMREHPEKALRIPMNDEHVRSLNVSNTVCMIVYEALRQQNFAGLELVHT
                     YEVDKLK"
     gene            complement(17863..18693)
                     /locus_tag="ACL29Z_001467"
     CDS             complement(17863..18693)
                     /locus_tag="ACL29Z_001467"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter transmembrane
                     protein EcfT"
                     /protein_id="HGR0069757.1"
                     /translation="MQAKLIGYQHRDTVIHRLSGAGKLLFFILVSLAVMISYDTRLLV
                     LIAIFSVFLLYLSKIHFKDVSFVAVFATVFAVLNVLMVYLFSPEYGVGLYGERSVIWQ
                     GIGAYTLTSQELFYLLNLAIKYLCTIPLAIIFLMTTHPSQFASSLNQIGVPYKIAYSV
                     SLTLRYIPDLQEEFFTIKMSQEARGMELSKKASLMQRIKGNLLIITPLIFSSLERIDT
                     IATAMELRRFGKEKKRTWYSYQALKKGDYITLLLATLFLVVSLLLILQNQGRFYNPWK
                     "
     gene            complement(18678..20360)
                     /locus_tag="ACL29Z_001468"
     CDS             complement(18678..20360)
                     /locus_tag="ACL29Z_001468"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000656554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGR0069758.1"
                     /translation="MKEAIIEWKDFSFRYETQQEPTLQGIDLTIYKGEKVLIVGPSGS
                     GKSTLGQCLNGIIPNIYKGQTYGEFLIKGQTAFDMSIYDKSHLVSTVLQDTDGQFIGL
                     SVAEDLAFALENDVTALDEMKGRVYKWAEKLDLLPLLDQRPQDLSGGQKQRVSLAGVL
                     IDESPILLFDEPLANLDPKSGQDIIELIDQIHKEEGTTTLIIEHRLEDVLHRPVDRIV
                     LINDGRILFNGSPDQLLATDLLTQNGIREPLYLTTLRQLGVDLVKEEQLADLDNLSIS
                     KGQVQLQTELVKETPELQSLFRLEEVSFSYDDRPILKSLHLDIKKGEKIAIVGKNGAG
                     KSTLAKAISSFIQTEGRYLWEKQDIKGDSVAERAERVGYVLQNPNQMISTNMIFDEVA
                     LGLRLRGVDEQEIETRVYETLKICGLYEFRNWPISALSFGQKKRVTIASILVLGAEII
                     LLDEPTAGQDQKNYTEIMEFLEELHQQGHTIVMITHDMQLMLDYSDRALVMVDGELIA
                     DTDPASLLSNPELLVKANLKETSIFNLAKKLDVDPLALTAFYKERREGCKLN"
BASE COUNT         5954 a         4566 c         3779 g         6288 t
ORIGIN      
        1 tatgtgcttc aagtatataa aaaggcgtaa aaatacgcct atagataatg gggttgaaat
       61 aggtttattg ttgatgagat tgtagataat tcaatttttt acttccaatc gaatattcaa
      121 aacctccacc ttttctgcct gtaattgttc atcataaaat tcaatatctt caggattttc
      181 cccttggcaa cctcggcaga aatattcttc cgctcgatca ggattcaaaa atcgacaagc
      241 acaaacaaaa cagtcgccat catcatttat tgagataata tagtagattg aaataagatg
      301 taaacaaatc gattaggaaa gttaaattag tttctagaaa tttttagcag atgtagtgta
      361 ctattctagt ctcaatttac tatggcttca aatatatctt tcgaaaaaat atttacagat
      421 gtgtaatttt gaagcttgca aaagttagta aacttgtaga tttcgatttg aagtaacttg
      481 ttttcttgcc cgatattgtt tttgaaattg aatttttcca tagtgactcc ttaattttct
      541 tctacacgtc tgatgataaa tctaattcgc aaaagagtca agaggatttt tcgaaaaata
      601 aatagcgacc gaaatcgcta ttttaagggt tataggtatt tgatggctta gactgctgtg
      661 tgactgttta cccacaggca atctttcttc tatattagta ttagtaaagg tctaaataat
      721 tatcaatttc ccattgtgaa acgaaggttg cataacttgc ccattcgatt cgtttggctt
      781 caaggaagct agtatagatg tgatctccga gagcagcttt aaccacttca tcttctgtca
      841 aagctttcaa agcgttgtga agagttgatg gaaggtctgt aataccagct tccttgcgct
      901 cttctgctgt catgatgtag atattttctt cgataggagc tggtgcttcg attttatttt
      961 caataccata caaaccaact tccaaaagaa cagccatagc aacgtaaggg ttcgccattg
     1021 gatccactga acgcaactca agacgagttc ccataccacg tgaagcaggt acgcgcacaa
     1081 gtggcgaacg gttacgacca gcccaagcaa tgtaaacagg cgcttcataa cctggaacca
     1141 aacgtttgta tgagttaact gttgggttca tgatggcagt atagttgtaa gcatgcttga
     1201 tcaaaccacc taggaaatgg taagctgttt ctgacaactg cattcctttt ggatcatttg
     1261 gatcaaagaa ggcgttattt ccttctgtat caaacaagga catattacag tgcatacctg
     1321 atccagcaat accaaatttt ggcttcgcca taaatgttgc gtaaagtccg tgtttgcgag
     1381 caatggtttt aacaacaagc ttaaagattt gaatcttatc acaagcacgg agaacttcat
     1441 cgtacttaaa gtcaatctca tgctgtccaa ccgcaacctc gtggtgactc gcttctactt
     1501 caaatcccat tttggtcaag acattcacaa tctcacgacg tgtgttgtcc gcaaggtcag
     1561 taggtgccaa atcaaagtag ccacccttgt cattcacttc aagtgttggg tccccatttt
     1621 catccaactt aaataggaag aattctggct ctggaccaag gttgaaggat ttgaatccaa
     1681 cttcttccat gtgacgaaga gctcgtttca aattaccacg agggtcaccc gcaaatggtt
     1741 caccttctgt tgtatagaca tcacagatca gacctgcaac acttccattt tcatctcccc
     1801 aagggaagac tgtccatgta tccaagtccg gatacaagta catatccgac tcattgatac
     1861 gtacaaaacc ttcaatagaa gatccatcaa acataacctt gttcgacaag accttatcta
     1921 actgttcatc tgtagcagga atttcgacgt ttttcatggt tcccaaaata tctgagaaca
     1981 taagacgaat aaaggtaaca tttttttcct tgacttcacg acgaatatct gcagctgtga
     2041 ttggcataag ttttctcctt aatctatgac tacttgcggt tgcctaaccg cgaccaaaag
     2101 gtgactgtac tgaagcaaaa cgcccctgtt ggaggagttc attgtgaagt gcacgacgta
     2161 cctcagtctg actaaccgct ttcttggatt tcgcttcacg ttcagcatat tttttcttaa
     2221 tggcagcgat attataacct tcagagatat aatctttgat ttcaagcaga cgatccatgt
     2281 cattcaagga atacatgcga cgatttcctt cgtttcgatc gggcttgatc aactcttgat
     2341 cttcataata acgaatctga cgcgccgata gatcggtcaa cttcataaca ctgccgatag
     2401 gaaaaacagc catatttcgg cgaaattctt tttccttcat ttacaatttc cttctttctg
     2461 tctattatag tctaaaaaaa gacaaacgtc aattgataat gttataaaat gtaacattat
     2521 ttttcttttt tctctaaaaa gagacgaata cgatcaatat cgtaatttac gataattgcg
     2581 acaaaaactc ccataaacgt ttctgataca cgcacaaaca cgtacgaaat tgtctcacca
     2641 cttggaattg atagggtaat gattaacata gctgctacac caccaataac ccctgctttg
     2701 ttattcattg ctacatttgt cataatggtt aacatggtgc agattggaac aactaccaag
     2761 gtcacccaaa aggcttcgtg gaaaaaggta tttaataaga agaagaccaa ggcatagagt
     2821 ccaccgatac tatttcctag aatacgcgaa gtcccaaaat gaacactctc atcaaaactc
     2881 tccctcaggc taaaaacggc tgtcaaagca ccaatttgaa gacctttcca gccaaaaaag
     2941 caaaaaatca agagaactag aaaaacagca atacctgttt taaaggttcg cataccaagt
     3001 ttgaactggg atttatcgaa tttatatttt ttaaaataac tcataatctc aactttctat
     3061 ttccatttta tcataaatcg gtgattttta tgagtaatag ttgagaggaa gcgtttttat
     3121 tttaagcaaa agaaaagagg aactttcatc cctctcttct ttgatttatt tataaaatct
     3181 tatttttctg tcaaggctgc aagtcctgga agaaccttac cttcaagaag ttccattgat
     3241 gctccaccac ccgtactaat ccatgagaac ttgtctgcac ggccaaggtt aatcgctgcg
     3301 gcagctgagt caccaccacc gatgattgat ttaactcctg gttgtttcac gatagcgtcc
     3361 atcacaccga ttgtaccagc ttggaaatct gggttttcaa atacacccat aggtccgttc
     3421 catacaactg ttttggcacc agtcaaagct tcgtcaaatt tggcgataga ttttggaccg
     3481 atgtcaagac caaggaagcc ttcagaaact gcttcacctt cagtgtcacg cacttcagtg
     3541 taaccagcaa atgcgttagc ttcttttgag tcaactggca agatcaattt accatttgct
     3601 ttttcaagaa gagctttcgc aacatccaat ttgtcttctt ctacaagtga gttaccgatt
     3661 tcgatacctt gtgctttgta gaatgtgtaa gtcatcccac caccgataag gactttatca
     3721 gctttttcaa gcaagttttc gataacaccg atcttgtctg aaacttttga accaccaagg
     3781 atagccacga atggacgttc tggagtttca actgcttctt ggatgtaggc aatttcgttt
     3841 tcaagaagga aaccagcaac tgctttttca acgtttgctg aaataccaac gttagatgcg
     3901 tgtgcacggt gagctgtacc gaatgcatcg tttacgaaga taccatctcc aagtgatgcc
     3961 cagtatttac caagttcagg atcgttttta gattctttct tgccgtcaac atcttcgtaa
     4021 cgagtgtttt caaccaagag aacttgtcca tcttcaagag cgttgattgc cgcttccaat
     4081 tcagcaccac gagtgacacc tgggaaaaca acatcttgac caagttttgc tgccaagtct
     4141 gctgctacag gagcaagtga tttaccagct ttatcagctt cttctttcac acgtccaagg
     4201 tgagagaaaa gaattgcacg tccaccttgt tcgatgatgt acttaatagt tggaagagct
     4261 gctgtgatac ggttatcgtt agtgattacg ccatctttca atggtacgtt gaagtcaaca
     4321 cgaacgagga cttttttacc tttcaagtca acgtctttaa cagtaagttt tgccatgtta
     4381 caaaaactcc tttatttatt ttattcgaaa ctattatatc acactttgga aatataagga
     4441 aagatttcac aagatttttc gatatttaat ctttatcttc tcttttccgt ctcaaggtca
     4501 aggctaaact agcaagacca aggctggcta agcctgctat tagggcttca ttagcatcag
     4561 ctgttcctgt atttggcaat tgtttgcttg cttcttctga tttaactgct gtattttgag
     4621 ctggtttttc ctgtgtagct actactgctg gtactgtttt tacttttgtt ccaatttcaa
     4681 caatttctgg aatcgcttct tggatgactt ctgttgaacg aagacgacgc tgaccctttt
     4741 catcaacttc aaagacatgt cttaacagtc catctcgtcc ctgtatgatg actcgttgtt
     4801 ccccaactag catctcagca ttttcatgct cttgacgatg aaaggcaacc ttttcctctt
     4861 gaacttccaa tttaggagcc ttttgttgat cagaagccgg ttgataagta ggttttggaa
     4921 ggactttgtt ttgtggtgct ggtttagcag gttgtggttt ttcagcagat tcataaacaa
     4981 aggcataatg agtaaagtgt ggtgctgtaa agataacatg actatccgtt tgttcaaaag
     5041 ccaattctac tgcctctttg ccttcaggta agaaaaatac tttcttaact ttcttatctt
     5101 tttcaattgg gattttcaca atagaagcgt aagagagatc aacatcttga cctttttcat
     5161 ccaaaccttc tatttcaaag acatgagcat cttctccagc aaagtatttc ttctcttcag
     5221 cacttgcttg aacacgctct actttcaaac ccttgatgac agtcttctct ttatttgaga
     5281 agtgtacttc aacacctgtt ttactatcag aaaagactgc tggcttgtct tctttcaata
     5341 aagcaaccag atcttttaga ctctgtttcg ctgttgcaag ctcttctgga ctcaaatcta
     5401 ctttttcaac caaggccttg tttttctcaa gaagcggagc tagggcagaa cctgaaggat
     5461 ggtttggttt ggcagccaag agttcttgaa cctcacctgt taagcgatca aactctgtct
     5521 tttcttcctt aaatttctct tgaccattca gagctttatg agcttctgtc aatttattaa
     5581 gtcggtcatt gacttgatct tgggtgctag tttcatggtc tttcaacact tgttcggccg
     5641 cttcaattgc tttcaagaag gcttctttta cttctgatga agcaaagtta tagaccacct
     5701 tgttcttagc agcttcaact tctgctaatt tttgtttgag gtactcatcg ttcaatgctg
     5761 cttttggaga taccaaaaca tcaaagctaa cttcatggcc ttggtaatga agcgtcaagg
     5821 tttgacgacc agtcttttga gcatcgtaac cagaaatttc aactccctca tcagtaaagg
     5881 aatgttcttc catggtgtca ttgctataag ccactgcaaa gcgtccttca gacaagtcta
     5941 agctatcacc aactaggtaa tcttttttcg gttcctgact tacttcaatt cccaaaatag
     6001 ttttcggact tgcttcatct tggccagtga cagtcactga caaattagca tttactggtt
     6061 gtcccaaata ttggagagta agattctgtt ctcccttatg atgcgtatca aaacctgata
     6121 ctgatacacc tgcgtgagtt aggcgaatga gttcgtcctc agttcctcct tcatactgaa
     6181 ctcgaagaac accacctcta aggtccaaat cctccccttc ggcgtagctt gttttcttag
     6241 gtcctgtttc taggctgact gacttgattc ttctgtcatc ttttggaacg gaaactgcta
     6301 ggacattact aatttccttg cctggcaact gggtacgata ataaagaaga ccagattgat
     6361 ttgtcaaatc caatggtgca cttgctaggt ctcctccaac ttcgctcttc aaggttgcga
     6421 gcggagtttg agaatttgga ttatcataaa cggtaatagt tgctccagcc ggtacatctg
     6481 caaagccaac ttgtaccttg ttattgccta gagaacgggc tgcagccttg gccatcggaa
     6541 tattgacact ctcagtatca agcttttcat acattttcca gttatagata cgaatagcct
     6601 tccatggagt tccattgtca gaagtgacaa cattcaagcg ccagtcttga gcagtgattg
     6661 gtttatcaag agtgatatct gtcacgtgtg ctttgttacc acggacttcc ttagctagct
     6721 tccactcacc atctgcatct ttataataaa ggtcaaagtc tttagtgttc atcaagccat
     6781 cgttaacaga ctcaccacca gcccctgcat gatccatgac ccatctaaca acggtacgtg
     6841 gcttggtcaa acgaatatcc acactaccac tcaactgagc tgaagaccat ttatctgaca
     6901 agctagtaat ggtaccgttc aacatacctt caataccttc tccaccttca gtcttaggga
     6961 aagtactatc aataactgtt gcacctggaa cgatattttc agctagtggt tttggtaggc
     7021 tggtatcttt tacagtcata ccccaatcaa aggttgtggt tgcagcttct gaacgaactc
     7081 catttttacc gactgctaca accttcagtt cttgagttgt accctgagca cttgctgagc
     7141 ggctaacttt tggtagataa atagttgtag aagatgagcc agttagtaat ttccagctgt
     7201 ctccatcttt ttcataaact tcatagaaat ctgcatcctt gttgccttta aattgcacaa
     7261 ctgcttccgc ttcttgggca tttttaagag attgtttcac tacagaaaag cttgtcggcg
     7321 attgtggctc ttggtgattg tccgagatag ttaattgtcc taggttgaac tgataatctt
     7381 ttacagcacc ttcatgctcg aaaaatagtt tgactgcata gatggtttta cctgctagtg
     7441 agctgagatc aaattcttca tttgtccagt tgtcagaaag ggttagctct ttccatgcat
     7501 ctgcatcatc gaatttgtag tctggagttg tagagaatgc catataaact ttagaacctt
     7561 ttcctccctt gtgggcaaca cgaagtttgg tcttctcagt tacttctaac ttagtagaat
     7621 aaagtctcac atcctgatct gtcttaccgg ctacatcacc agagaattta agggaatttc
     7681 cgccattata ggcatctgta aaatcatatt ctgcacgaag tttttcccct gttgaagtct
     7741 gccaccagcg ccatgttgga agaacacctg atactgaacg ataattccac tcagaatcct
     7801 tagaaacctt accatctacg aaccattttt taccatgacc tgtattaaaa gaagtagtaa
     7861 aagtattacc taccgctggc gtacggtccg caactaggtt agcaatacca taccaatctt
     7921 tgtcacctgg tttttggcca gtagggtctc cttgataacc tgtaaagaag atatcttcat
     7981 ttttatgata atcttcacca gtttttccta aacttgtaat ggtatctggg gcaaataaac
     8041 caagagaaag gcgcaatttc ccattttcgt ctaaaatgtc attccactta acctttgtct
     8101 tgtaggaacc accctgttgc aattccaaac ctgcaaatac atcataagga ttacgaccaa
     8161 tccagttggc agttgcaata gtgtaatcat ttttagcctt atcccagtta aagttagcaa
     8221 agaagttatc tgccggaacc ttatctcctt ctggttgcat gaattggtag ttgtattctc
     8281 ccaaaccatc ttgatgataa cgtccatagt tataggtcat ggcatcgtac caagaatact
     8341 tgattggatg gtttacctta gcagcatatt ccttgctata gagcataaac tggcgcatct
     8401 tttctccaag aggtttaacc aaatctccag ttgtttcttg gttgatgaaa tagccatcat
     8461 agccataata cttggccatg tctaccaatt tacgggcaat tgggaagcta ccatctgcgt
     8521 cttgcttcaa agcttcagca aatctttctt gatctgcaat actattagac cagttgaaga
     8581 agagtgtacc gtatacagga accccgttac ggtgacctgc atcaataacg tcaggagttg
     8641 gtacgagacc ttcccagaag accattgaat ctagatattg ccaatagtca aaagcatagg
     8701 ccttgaactc ttctccacca acagaagcat ggtcttttgc tttagaattg gtgtttgata
     8761 aggcttgaac ttttgcttcc ttgctagctt tttcattgac taaatgacct gtccgacgtg
     8821 aagcgaggac aacagatccg cggttaatag catcatcttc acgagcacct ggttcccatt
     8881 ttaacaattc ttcccaagaa ttaaatttga tttcctttgg ttttaatgtt ttttctgtat
     8941 ttttagggac atctggctgg acttcttttt cagtcttatt agcttctgct gctggtttag
     9001 actcatcccc ttggttagtt gcttcgggct ttgcttctgt ttccttgtca gacttaggtt
     9061 ttgcttctgc agatggtgtt tctgcaacca cctcacttgc tttttcctct ggtttagctg
     9121 cgctagctgc ttctgcagtt tcagtagttg cagcttcatt gcttgctggc gaagcagttt
     9181 cagatgctat cgctactcct tctgcctttt ctagcttgtt ttctctagca tgttcccctt
     9241 cattctgctt atcagcttca ttggtcgaat gctcactctc tcctgaaaca agctctgtat
     9301 tagctccgct attttcagga actgcagttt cttcagccaa ggctggacca gcaaataaaa
     9361 cagcaccaat catcagcgag caggctccta ctgataactt acgaatactg taacgacaac
     9421 gtctttcaaa aaatggattc ttcattttct cctcctaaaa gattgatttt gttgttttca
     9481 agaaagcgct ttatattctg tagtttttta tcaaactcta gaaccatgat aatcacattt
     9541 ttatcctaaa acatttttag acaaaaaaca ataactgttt gcacaaatct aaaataaggt
     9601 taaaaactct taaaaataat acacttatca attataattt tcttttacaa acttgacatt
     9661 aacacttgtt agatttactt ttatccttta aaatagaata ggagatattc cgcgattatt
     9721 tttcggagga aaaagaaatg tccattaatt ggcaggaaat tttatttcac tttttaggtg
     9781 gtctggggct attcttatat agcatcaaga ccatgggaga cggtttgcaa caagctgctg
     9841 gagatcgcct tcgtttttac attgacaaat atactagtaa tcctttcttt ggagttctgg
     9901 ttggtattgg gatgactgct ctaattcagt ctagttctgg tgtaacagtt atcacagtcg
     9961 gcctggtcag tgccagtctc ttaaccttac gtcaggctat cgggattgtc atgggtgcta
    10021 atattgggac aactgtcaca tcctttctca tcggttttaa attaggtaac tatgccctac
    10081 ctatgctctt tatcggtgcc gtctgtctct tttttacaaa aaatcggaca gtcaataata
    10141 tcggacgcat cctctttggt gtcggtggta tcttttttgc cctcaatctc atgagcggcg
    10201 caatggctcc actcaaggat ttacaggtct ttaaggacta tatgattgag ctaagtaaga
    10261 atcctgtttt gggtgtcttt gtcggtaccg gcttgacctt gctaattcaa gcttcttcgg
    10321 ctaccattgg gattttacaa aacctctacg ccggcaatct aattgaccta cagggagctt
    10381 tgccagttct atttggtgac aatatcggga caaccattac agccatcatt gcctctttag
    10441 gggctaatat tgcagctaaa cgggtagcag gagctcatgt tgccttcaac gttatcggaa
    10501 cagtcgtctg cgttattttt ctagttcctt ttactgtcct gattcattgg tttgaagcta
    10561 cgctaaatct agcaccggaa atgaccatcg cctttgctca cggaaccttt aatattacca
    10621 acaccattgt ccaatttcca tttatcggag ctctggctta ctttgtaacc aagattattc
    10681 ctggagagga cgaggttgtc aaatacgaac ccttatatct tgatgaacat ttcatcaaac
    10741 aggccccatc tatcgctcta ggaaatgcta agaaagagct cttgcactta ggaaactacg
    10801 ctgctaaagc ctttgacctt tcctataagt acatcattga tttggatgaa aaagttgctg
    10861 aaaaagggca taaaaccgaa gaagcaatta acaccatcga tgagcaatta acacgttatc
    10921 tcattgccct ttcaagcgaa gctctcagcc aaaaagaaag tgaagtgctt accaatatcc
    10981 ttgattcctc ccgtgatttg gaacggattg gagaccacac ggaggctcta ctcaatctga
    11041 ctgactatct tcaacggaaa aatgttgaat tttctgatgc cgccttgaaa gaattagagg
    11101 aagtttaccg ccaaactagt gactttatca aagatgctct ggatagtgtg gaaaacaatg
    11161 atattgaaaa agcacgcagt cttgtagaac gtcatgaagc aatcaataag atagaacgtg
    11221 ttctcagaaa aacccacatc aaacgcctca acaaaggcga atgttcaaca caagctgggg
    11281 tcaactttat cgacatcatc tcacactaca ctcgtgtatc agaccacgct atgaaccttg
    11341 ctgaaaaggt ttttgcagaa caaatctaag aaccaagaag ctatccatca taattggatg
    11401 gctttttact ttttcctaag caagactagg ctgaatgaaa ctgaaagagt attctgcaga
    11461 tatatagtat attgaaacta gaatagtaca cctctatttc taaaacattg ttagaaatcg
    11521 atttgactgt cctgatcgat ttgtcctgtt attatttcat tttactatag tggattaaat
    11581 taaaaaagta taatgtattg aatctataac agtacatctt gactgctaaa atatttctat
    11641 aaattaattt gacttttctg atagagatgt tcacatctta tttcaattca tgatacaatc
    11701 cagttcctaa aactttgcta gaaattgatt tggctttccg aattaatttg ttcaaatttt
    11761 atttcatttc aatatactga taaatccatt cactagcaca gggcaagagg gagtcgctat
    11821 tgatttcaac ggtagcaggt acatacagag gacccctacc tcagatatac tgcaatatca
    11881 tcgtatgcaa aaaacctctg agatttttct caaaggttct gattttgcta attgctgttc
    11941 tcaaccgctg cagtaacaaa ggcagtgtag agttcttctg gtcggtttgg acggcttgac
    12001 agttcagggt gatactgaca agctacaaag aatttatttt caggaatttc cacgatttct
    12061 accaaacgat tgtctggaga aactcctgaa aagacaaaac ctgctgcctc aaactgctca
    12121 cggaaggcat tattaaactc ataacggtga cggtgacggc gttgcaccac ttcttgattg
    12181 tgataagcag cagcagcctt agagccacgt ttcaacttag acggataaag tcccaaacga
    12241 agggttccac ccatatcctc aatatcaatc tgatcacgca tgatatcaat gatagggtat
    12301 tttgtttctg gtgcaagctc tgcagaattg gcaccttcaa gacctaaaac gtgacgagca
    12361 aactcgatac atgtcaactg cattcccaag cagactccca acattggaac atcattttca
    12421 cgcgcatagc ggatggcttg gattttccct tctgtaccac gttgaccaaa accacctggt
    12481 acgatgatcc cgtccgcatc agacaagagt tctgctacat tctctgctgt cacatcattg
    12541 gcattgaccc aattgatttt aacttctaca tcattgacat agccagagtg tttcaaggct
    12601 tcgaccactg agatataggc atcttgcaac tccacatact taccaacaag ggaaatctta
    12661 acttgtttct tgaggttcat gaccttgtcc accatggctg accattctgt catatccgct
    12721 gctggtgcgt ctaatttcaa atgatcacaa acaatttggt ccatcccttg tgcctgcaag
    12781 ttcagtggaa tttggtaaag gtgttcaaca tccaacgatt cgataacggc ttctggtgcc
    12841 acatcacaga actgggccag tttattttta attccttgac cagctggctc ttctgtacga
    12901 ataaccaaca tatttggttg gattcccaag ccacgcaatt ctttgacaga gtgttgggtt
    12961 ggtttggttt tcatttcacc agcagccttg aggtaaggaa gcaaggttgt atggatatac
    13021 atgacattat ccgcacccac atctgccttc atctgacgaa gagcctctag gaatggcaag
    13081 gactcgatat ctcctactgt tccaccaacc tctgtgataa tgacatcaga gtcggtcgtt
    13141 agagcggcac gcttgatttt ttctttcaaa gcatctgtga tatgaggaat gacttgaaca
    13201 gttgccccaa ggtattctcc acggcgttct ttacgaagaa cttcactgta aattttccca
    13261 gttgtcacgt tggaatattt gttgagattg atatcgatga aacgttcata gtgacccaag
    13321 tccaaatctg tctcagctcc gtcatctgtc acaaaaactt ccccgtgctg gtaaggactc
    13381 atggttcccg gatcaatatt gatataaggg tcaaactttt gaatggttac tttgagacca
    13441 cgatttttca agagacggcc tagactcgct gccacaatcc ctttcccaat agacgatacc
    13501 acaccaccag ttacaaaaat atatttcgta gacatagatt cctctttcta aaatgctcaa
    13561 ggtcttgtta actacgaggg gatatagaaa acaagaccct actaataaga ataatctggg
    13621 acgactgcac cagattcaca gctaatactc ttcgaaaatc tcttcaaacc gcgtcaacgt
    13681 cgccttgccg tagatatgtg ttcctgactt tgtcagtctt atctacaacc tcaaaatagt
    13741 gttttgagca gcctacggct agtttcctag cttgctcttt gattttcatt gagtataaaa
    13801 tacaagaaga taacttcttg aaaaaacaaa aatagctccc taagaactag ggagccccga
    13861 cctctaaaag aggtgcccaa acaatatgat acctaaaaat aggataattg tcaatagcta
    13921 actcttattc ctcgctggtt tcagcgtcgt catctgaaaa ctcgtcgtcg tcttcgttga
    13981 gatccacatc ttctcccaag tcatctggag cgatttcgtt gatttctgca tcataagctt
    14041 ccacttcatt tttttcatca tctggatttt catcatcgta tgaaagagct ggatctgctt
    14101 cgtatgcatc ttcgtcttct ggatcatctg cattgtagtc aatggcatct gaatcaccat
    14161 ccataaaggc attgacacgt tttttcttag cttttggtgc tacttcatcg tcgtcatttt
    14221 cttcaagagc gatgatttct tcgtcgattt cgtccacacc ataccatgaa cgaagacccc
    14281 atttgttgtc cccaagtgag atgaagctac cgtcaaagtt caactctgtg tagaacaaag
    14341 gcaaagcttc gcggatatcg ctgtttgatg ttccaaggta gttttgaatt tcgtttacaa
    14401 gatcgctaaa atgcatctca tgatcgcgac cacgaagttc caagatagca cgcgctacct
    14461 caatcataga tagttcactt ttttcttgcc cagcaaatac ttctaattcc aaagcgtttc
    14521 tcctcattta tactactatc gccagagcga acagactctg acctcatttt atcatttact
    14581 ctttatttta cgataatttt gcagaatagt caaaggttaa gggggagaaa atggcaggat
    14641 tagactaatt ccaatataaa actcattcct ttttctgttg ctccattttc cacaaatcca
    14701 agcgacttga aacacctcct agaagcatga ttgtaggtgt agatttcctt gactctcaat
    14761 tctttccatc cttttactcg agccaattca atcaaagcac ttagaatctt ttttccaagt
    14821 cctcgatgtt ggtaagcgga attcccaatc acaatgggga gattatcctg agatagtgta
    14881 atatccccaa ttggaaacca ttctcccttc tccttgactt caatccaaaa aagctcacca
    14941 tgccgatcca aataggaata catggcttcc aaggtcgctt gactgtaagg aagcttcacc
    15001 ccatctacga ggtaaaccaa gttcacatcc tgataccaag caaaagcttc ctcacaatga
    15061 ttgaccttat aataaggaac aaaacacaat gcactacctt ttcaacaaaa gagttgctgc
    15121 ttgattaaaa ccatcacacc agttatacca ttttgcttca tacccatctt gagctaggat
    15181 acgatcttct aaatcaaaaa cagagtaaat ctttctttcc tcgcaagctt gcgcatagag
    15241 atgatatagt tcatcaccac catctctatc ccactcagca gaaatcgtat cccgatctgc
    15301 caataaagtc tgataagccc tgtgatgccc atctgtaatc agcaaacaat ctccaaaggc
    15361 aagaatactg attggatcga cttggattgt ttctgccgac tggtaaagca tctgaatatc
    15421 ttgcaacttc ttttctgata aatatagttg agtcggatga agatctgcta tgttgacttt
    15481 catttctttc tcctcaaggg aattcgatac tcacttctgt ttgcctttaa atcgccattg
    15541 gaagcggagc ttgtcataga agggaaactc gataaacagg actcccaagc ccacacagag
    15601 actggcaagg acgtctgatg ggtaatgaac tcccagatag actcttgata ccagcacact
    15661 gactaggtag aggccaagga cgatttgtac gatttttctc cagactggat ctttaatccg
    15721 ctgactaaga ataacaatca aagtacctac catcaaggtt acagccagag aatgcccact
    15781 tgggaaggaa aatcccttct cctccaccag atgtaagata tctggccgtg ggcgctggta
    15841 gatattttta aaggtcacga ttaaaagacc taccaaagcc agatttccca gcatgaagaa
    15901 actttctatc ttccatcgct tacgataaaa gacaaaagct gtaatgacaa cccaagtgat
    15961 aatcactggg atatcaatca gacgtgtgag ggctcgaaaa agaatagtca aataatctgg
    16021 taagtctcct cgaatggcag tctgaatcga ttggtcaaaa ttgaccagcg tttcagggta
    16081 aaatttgacc atgtagccaa gaataacgaa aagtaaaagg gcaaaactgc ccttcattaa
    16141 aaatgtttgt ttatctctca taatgtttta aggttggttt caagagaaca tacaacaacc
    16201 agaatgaaac ggaaaagata acaccttcaa tcaagttaaa aggtaatacc atggtcatta
    16261 ggtagttgga aagtcccaaa atttttccaa tatcaaagtt agcaaactta gcgtacaaag
    16321 gaacagcata aacatagttg agaaccaaca tgaccaaggt taaaccaata gttccagcta
    16381 gagagcctag taggaaacga agggttgtcc gttccttttt ccaaatcaaa gcaaatacga
    16441 tgacaaaaac tcccaaagct acgatattca tcggcaaacc aatgtaagta ttcactcctt
    16501 ggctgttaag aagcaacttc aagagtgagc gaagcaagag cactcctaga gcagcaggca
    16561 aatccatgac caccagaccc acaaggactg gcaagatact aaattcgatc ttgaggaaag
    16621 atgccgctgg taaaagcgga aaatcaaagt acatcagcac aaatgagatg gctgatagaa
    16681 ttgcaatggt cgaaagtcga cgtgtgtttg tcataacagg ttcctccaat tttctataaa
    16741 atcagaagaa gttggaaagg attcctctat ctattctcac tttttatatc ccaaaagttc
    16801 cctcttactc tattaaagaa aaacaaagca agtggttaca atccggctat aaatctatca
    16861 aaacagacaa agctattctt tcgtcttctc ccatccagac tatactgtcg gttgtggaat
    16921 ctcaccacat cagcttgcgc tcgcggactt ctttaaagag aaagaaatag agatttttct
    16981 tttagactag gcgacaagct gtaggcataa cttctggtta ggcaaagctt gtcaacaaag
    17041 tataaaagga aaagatcatt tcctagttaa agtcaccgcc ggtcgggaat cacaccctgc
    17101 cctgaagact cttttatcat aacaaaaaac gcttgcaagc gcaagcattt tgttcatttt
    17161 cattttttat ttcaatttat ccacttcata ggtatggacg agctcaagac ctgcaaagtt
    17221 ctgctggcga agagcctcat agacaatcat gcagacggta ttagacacat tgagactgcg
    17281 gacatgttca tcattcatgg gaatacggag agccttctca ggatgttctc gcataaaatc
    17341 ttcaggtaag cccttgtctt cacgtccaaa gagaaaataa tggtcctcgt cagtcgataa
    17401 atccacctca gaatagattt tttccgcgaa tttcgaaatc agatagagtt ttcccttcat
    17461 ctgagatatg aaatcttcta aactctcgta aaaataaatc tctagcttat cccagtaatc
    17521 caatccagcc cgcttcatct tgcggtcatc aataggaaag cccataggct tgatgatgtg
    17581 gaggggagaa ttggtcgcag cgcaagtacg cgcgatattg cctgtatttt gtggaatttg
    17641 aggttcaaat aatacaatgt gatttgtcat gacttgcttc ctttcaccat tgcaaaaaaa
    17701 tagccacact gcccggagtc aagctcagca aacagcgtgg ttaaggcatc gttaacttac
    17761 ctcacaacag gtttgaagta aatcagcgaa actactttct tagtataaca ctttcagaat
    17821 cattgtcaat agaaacgact taattttttc aattttttca agctatttcc aagggttgta
    17881 aaatcgtccc tgattctgca agataagtag taaactaact actaaaaaca aggttgccaa
    17941 gagcaaggta atatagtctc cttttttcaa ggcctgataa ctataccatg tgcgtttttt
    18001 ctctttccca aatcggcgaa gctccatggc ggtcgcgatg gtatcaatcc gttctaacga
    18061 gctaaaaatc aagggagtaa taatgagcag attgcctttg attcgttgca taagagaagc
    18121 tttcttggat aattccatcc cacgcgcttc ctgagacatc ttgatggtaa agaattcttc
    18181 ctgcaaatct ggaatatagc gcaaggttag actgacagaa taggcaatct tgtaaggcac
    18241 accaatttga tttaaactgg aagcaaactg actagggtgg gttgtcatca aaaagataat
    18301 agccagagga atagtgcaaa ggtacttaat agccaaattt agcagataaa agagctcttg
    18361 actggtcaga gtgtaggcac cgattccctg ccaaatcaca cttctctctc cgtaaagtcc
    18421 aaccccatac tcgggagaaa agagatagac catcaaaacg tttaaaacgg caaataccgt
    18481 cgcaaaaaca gctacaaagg aaacatcttt aaaatggatt tttgacaaat agaggagaaa
    18541 gaccgaaaag atggcaatca gaacaagcag tctggtatca tagctaatca tgaccgccaa
    18601 tgacacgaga atgaaaaaga ggagtttccc agcgcctgac aagcgatgaa tcacagtatc
    18661 tctatgctgg taaccgatta atttagcttg catccttctc tcctttcttt gtaaaatgcc
    18721 gttaaagcaa gtggatccac gtcgagtttc ttagccaagt tgaagataga agtctctttt
    18781 aggttggctt ttactaacag ctcaggattg ctcaacagac tagctggatc agtatcagca
    18841 atcaattccc catccaccat gacaagggct cgatctgaat aatccagcat caattgcata
    18901 tcatgggtaa tcatgacaat ggtatgccct tgttgatgca gttcttcgag aaattccata
    18961 atctcagtat agttcttctg gtcttgaccc gcagtcggtt catctaggag gataatttca
    19021 gcgcctaaga ccaaaattga ggcaatagtc acacgttttt tctgaccaaa tgacagggca
    19081 gaaatgggcc aattacggaa ttcatagaga ccacagattt tcaaggtttc atagactctc
    19141 gtttcaattt cctgctcgtc cacacctcgc aaacggagtc ccagagccac ctcatcaaaa
    19201 atcatattgg ttgaaatcat ttgattggga ttttgcagca catagcctac tcgttccgcc
    19261 cgctctgcaa cagaatcgcc ttttatatcc tgtttttccc aaagatagcg tccttccgtc
    19321 tgaataaagc tacttatagc cttggctaga gttgatttcc ctgctccatt ttttccgaca
    19381 atggcaatct tttcaccctt tttaatatct aaatgtaggg attttaaaat cggtctatca
    19441 tcataagaaa aagatacttc ctctagtcta aagagtgact gcaattctgg ggtttctttt
    19501 accagttccg tctgtaactg gacttgccct tttgagatag acaagttatc cagatctgct
    19561 aattgttctt ccttgactaa gtccacacct aattgacgga gagtcgttag ataaaggggt
    19621 tctcgaattc cattttgagt caataaatca gtcgcaagca actggtcagg gctcccatta
    19681 aaaaggatac gaccatcgtt tatcaagaca atccgatcca cagggcgatg cagaacgtcc
    19741 tccaaacggt gctcgataat cagagtcgtc gtcccctctt ccttatgaat ctggtcaatc
    19801 aattcgataa tatcctgacc tgacttggga tctagattgg cgagtggctc atcaaacaag
    19861 agaatcggac tttcatcaat caagacacca gccagactga ctcgctgctt ttgtccacct
    19921 gacaaatcct gaggacgctg atccagtaaa ggaagaaggt ccagcttttc agcccattta
    19981 taaacacgac ctttcatctc atctagggct gtcacatcat tttccagagc aaacgccaaa
    20041 tcttctgcca cagacaagcc aataaactgc ccatctgtat cctgcaaaac tgtgctaacc
    20101 agatgagact tatcatagat gctcatatca aaggctgttt gaccctttat caaaaattct
    20161 ccatatgtct gacccttgta aatattggga ataatcccat tcaaacactg acccaaggta
    20221 gatttacctg acccagatgg tccaacaatt aagactttct ctcccttgta aatggtcaag
    20281 tctatccctt gcaaggtcgg ttcttgttgt gtttcatacc ggaaagagaa atccttccac
    20341 tcaattatag cttctttcat cttactctct tcattcgctt cttagacttc tattttatca
    20401 taaatcaagc ccttcttgca gtctcttctc ttaaaatctt agcaccaaaa agattcctat
    20461 cctagcttac ttgcctaact aatctataaa catcgaaaaa gactagttgc ccagccttcc
    20521 ccatcatttt atactcttcg aaaatctctt caaaccacgt cagcttcgcc ttgccgtagg
    20581 tatggtt
//
LOCUS       DBEJAU010000038        20349 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC323 isolate 683620
            SAMN38261939-rid24807223.denovo.038, whole genome shotgun sequence.
ACCESSION   DBEJAU010000038 DBEJAU010000000
VERSION     DBEJAU010000038.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261939
            Sequence Read Archive: SRR26833919
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 20349)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20349)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576303.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576303.1
            Genome Coverage       :: 154x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/19/2025 01:05:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,121
            CDSs (total)                      :: 2,078
            Genes (coding)                    :: 1,943
            CDSs (with protein)               :: 1,943
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 36
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 72 of 135
            Pseudo Genes (incomplete)         :: 63 of 135
            Pseudo Genes (internal stop)      :: 51 of 135
            Pseudo Genes (multiple problems)  :: 46 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20349
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261939-rid24807223.denovo.038"
                     /strain="GPSC323"
                     /isolate="683620"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            64..606
                     /locus_tag="ACL29Z_001469"
     CDS             64..606
                     /locus_tag="ACL29Z_001469"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HGR0069759.1"
                     /translation="MQESNKRLKTKRTIENAMVQLLMEQPFDKISTVKLVEKAGISRS
                     SFYTHYKDKYDMIEHYQSKLFHTFEYIFQKHAHHKRDAILEVFEYLESEPLLAALLSE
                     NGTKEIQNFLRNKLHIMLSTDLQKRFMQLNLNTTELEYSSIYLTHALFGVCQTWIAHG
                     KKESSQEITDFLMKMLGDTN"
     gene            complement(647..720)
                     /locus_tag="ACL29Z_001470"
     tRNA            complement(647..720)
                     /locus_tag="ACL29Z_001470"
                     /product="tRNA-Asn"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(684..686),aa:Asn,seq:gtt)
     gene            complement(726..797)
                     /locus_tag="ACL29Z_001471"
     tRNA            complement(726..797)
                     /locus_tag="ACL29Z_001471"
                     /product="tRNA-Glu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(762..764),aa:Glu,seq:ttc)
     gene            complement(849..1601)
                     /gene="comE"
                     /locus_tag="ACL29Z_001472"
     CDS             complement(849..1601)
                     /gene="comE"
                     /locus_tag="ACL29Z_001472"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000866065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence system response regulator
                     transcription factor ComE"
                     /protein_id="HGR0069760.1"
                     /translation="MKVLILEDVIEHQVRLERILDEISKESNIPISYKTTGKVREFEE
                     YIENDEVNQLYFLDIDIHGIEKKGFEVAQLIRHYNPYAIIVFITSRSEFATLTYKYQV
                     SALDFVDKDINDEMFKKRIEQNIFYTKSMLLENEDVVDYFDYNYKGNDLKIPYHDILY
                     IETTGVSHKLRIIGKNFAKEFYGTMTDIQEKDKHTQRFYSPHKSFLVNIGNIREIDRK
                     NLEIVFYEDHRCPISRLKIRKLKDILEKKSQK"
     gene            complement(1598..2923)
                     /gene="comD"
                     /locus_tag="ACL29Z_001473"
     CDS             complement(1598..2923)
                     /gene="comD"
                     /locus_tag="ACL29Z_001473"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000362880.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence system sensor histidine kinase ComD"
                     /protein_id="HGR0069761.1"
                     /translation="MDLFGFGTVIVHFLIISHSYHFICKGQINRKELFVFGAYTLLTE
                     IVFDFPLYILYLDGLGIERFLFPLGLYSYFRWMKQYERDRGLFLSLLLSLLYESTHNF
                     LSVTFSSITGDNFVLQYHFPFFFVVTVLTYFVTLKIIYYFHLELAYFDEDYLYPFLKK
                     VFFALLLLHIVSFVSDMVSTIKHLNSFGSILSSIVFISLLLTFFAMNSHKVQMEKEIA
                     LKQKKFEQKHLQNYTDEIVGLYNEIRGFRHDYAGMLVSMQMAIDSGNLQEIDRIYNEV
                     LVKANHKLRSDKYTYFDLNNIEDSALRSLVAQSIVYARNNGVEFTLEVKDTITKLPIE
                     LLDLVRIMSVLLNNAVEGSADSYKKQMEVAVIKMETETVIVIQNSCKMTMTPSGDLFA
                     LGFSTKGRNRGVGLNNVKELLDKYNNIILETEMEGSTFRQIIRFKREFE"
     gene            complement(2944..3069)
                     /gene="comC"
                     /locus_tag="ACL29Z_001474"
     CDS             complement(2944..3069)
                     /gene="comC"
                     /locus_tag="ACL29Z_001474"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000799689.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence-stimulating peptide ComC"
                     /protein_id="HGR0069762.1"
                     /translation="MKNTVKLEQFVALKEKDLQKIKGGEMRLSKFFRDFILQRKK"
     gene            complement(3234..3307)
                     /locus_tag="ACL29Z_001475"
     tRNA            complement(3234..3307)
                     /locus_tag="ACL29Z_001475"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(3271..3273),aa:Arg,seq:tct)
     gene            complement(3351..3830)
                     /gene="rlmH"
                     /locus_tag="ACL29Z_001476"
     CDS             complement(3351..3830)
                     /gene="rlmH"
                     /locus_tag="ACL29Z_001476"
                     /EC_number="2.1.1.177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000695929.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008168 - methyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0006364 - rRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA
                     (pseudouridine(1915)-N(3))-methyltransferase RlmH"
                     /protein_id="HGR0069763.1"
                     /translation="MKIKVVTVGKLKEKYLKDGIAEYSKRISRFAKFEMIELSDEKTP
                     DKASESENQKILEIEGQRILSKIADRDFVIVLAIEGKTFFSEEFSKQLEETSIKGFST
                     LTFIIGGSLGLSSSVKNRANLSVSFGRLTLPHQLMRLVLVEQIYRAFTIQQGFPYHK"
     gene            4013..5194
                     /locus_tag="ACL29Z_001477"
     CDS             4013..5194
                     /locus_tag="ACL29Z_001477"
                     /EC_number="3.4.21.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000681590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004252 - serine-type endopeptidase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="S1C family serine protease"
                     /protein_id="HGR0069764.1"
                     /translation="MKHLKTFYKKWFQLLVVIVISFFSGALGSFSITQLTQKSSVNNS
                     NNNSTITQTAYKNENSTTQAVNKVKDAVVSVITYSANRQNSVFGNDDTDTDSQRISSE
                     GSGVIYKKNDKEAYIVTNNHVINGASKVDIRLSDGTKVPGEIVGADTFSDIAVVKISS
                     EKVTTVAEFGDSSKLTVGETAIAIGSPLGSEYANTVTQGIVSSLNRNVSLRSEDGQAI
                     STKAIQTDTAINPGNSGGPLINIQGQVIGITSSKIATNGGTSVEGLGFAIPANDAINI
                     IEQLEKNGKVTRPALGIQMVNLSNVSTSDIRRLNIPSNVTSGVVVRSVQSNMPANGHL
                     EKYDVITKVDDKEIASSTDLQSALYNHSIGDTIKITYYRNGKEETTSIKLNKSSGDLE
                     S"
     gene            5252..6010
                     /locus_tag="ACL29Z_001478"
     CDS             5252..6010
                     /locus_tag="ACL29Z_001478"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000410347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParB/RepB/Spo0J family partition protein"
                     /protein_id="HGR0069765.1"
                     /translation="MEKFEMISITDIQKNPYQPRKEFDREKLDELAQSIKENGVIQPI
                     IVRQSPVIGYEILAGERRYRASLLAGLRSIPAVVKQISDQEMMVQSIIENLQRENLNP
                     IEEARAYESLVEKGFTHAEIADKMGKSRPYISNSIRLLSLPEQILSEVENGKLSQAHA
                     RSLVGLNKEQQDYFFQRIIEEDISVRKLEALLTEKKQKKQQKTNHFIQNEEKQLRKLL
                     GLDVEIKLSKKDSGKIIISFSNQEEYSRIINSLK"
     gene            6223..7584
                     /gene="dnaA"
                     /locus_tag="ACL29Z_001479"
     CDS             6223..7584
                     /gene="dnaA"
                     /locus_tag="ACL29Z_001479"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003688 - DNA replication origin binding
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006270 - DNA replication initiation
                     [Evidence IEA];
                     GO_process: GO:0006275 - regulation of DNA replication
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="chromosomal replication initiator protein DnaA"
                     /protein_id="HGR0069766.1"
                     /translation="MKEKQFWNRILEFAQERLTRSMYDFYAIQAELIKVEENVATIFL
                     PRSEMEMVWEKQLKDIIVVAGFEIYDAEITPHYIFTKPQDTTSSQVEEATNLTLYNYS
                     PKLVSIPYSDTGLKEKYTFDNFIQGDGNVWAVSAALAVSEDLALTYNPLFIYGGPGLG
                     KTHLLNAIGNEILKNIPNARVKYIPAESFINDFLDHLRLGEMEKFKKTYRSLDLLLID
                     DIQSLSGKKVATQEEFFNTFNALHDKQKQIVLTSDRSPKHLEGLEERLVTRFSWGLTQ
                     TITPPDFETRIAILQSKTEHLGYNFQSDTLEYLAGQFDSNVRDLEGAINDITLIARVK
                     KIKDITIDIAAEAIRARKQDVSQMLVIPIDKIQTEVGNFYGVSIKEMKGSRRLQNIVL
                     ARQVAMYLSRELTDNSLPKIGKEFGGKDHTTVIHAHAKIKSLIDQDDNLRLEIESIKK
                     KIK"
     gene            7743..8879
                     /gene="dnaN"
                     /locus_tag="ACL29Z_001480"
     CDS             7743..8879
                     /gene="dnaN"
                     /locus_tag="ACL29Z_001480"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000581170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009360 - DNA polymerase III complex
                     [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit beta"
                     /protein_id="HGR0069767.1"
                     /translation="MIHFSINKNLFLQALNTTKRAISSKNAIPILSTVKIDVTNEGIT
                     LIGSNGQISIENFISQKNEDAGLLITSLGSILLEASFFINVVSSLPDVTLDFKEIEQN
                     QIVLTSGKSEITLKGKDSEQYPRIQEISASTPLILETKLLKKIINETAFAASTQESRP
                     ILTGVHFVLSQHKELKTVATDSHRLSQKKLTLEKNSDDFDVVIPSRSLREFSAVFTDD
                     IEAVEIFFANNQILFRSENISFYTRLLEGNYPDTDRLIPTDFNTTITFNVVNLRQSME
                     RARLLSSATQNGTVKLEIKDGVVSAHVHSPEVGKVNEEIDTDQVTGEDLTISFNPTYL
                     IDSLKALNSEKVTISFISAVRPFTLVPADTDEDFMQLITPVRTN"
     gene            8944..9138
                     /locus_tag="ACL29Z_001481"
     CDS             8944..9138
                     /locus_tag="ACL29Z_001481"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF951 family protein"
                     /protein_id="HGR0069768.1"
                     /translation="MYQVGNFVEMKKSHACTIKSTGKKANRWEITRVGADIKIKCSNC
                     EHVVMMGRYDFERKMNKIID"
     gene            9222..10337
                     /gene="ychF"
                     /locus_tag="ACL29Z_001482"
     CDS             9222..10337
                     /gene="ychF"
                     /locus_tag="ACL29Z_001482"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002269933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="redox-regulated ATPase YchF"
                     /protein_id="HGR0069769.1"
                     /translation="MALTAGIVGLPNVGKSTLFNAITKAGAEAANYPFATIDPNVGMV
                     EVPDERLQKLTEMITPKKTVPTTFEFTDIAGIVKGASKGEGLGNKFLANIREVDAIVH
                     VVRAFDDENVMREQGREDAFVDPLADIDTINLELILADLESVNKRYARVEKMARTQKD
                     KESVAEFNVLQKIKPVLEDGKSARIIEFTDEEQKVVKGLFLLTTKPVLYVANVDEDVV
                     SEPDSIDYVKQIREFAATENAEVVVISARAEEEISELDDEDKKEFLEAIGLTESGVDK
                     LTRAAYHLLGLGTYFTAGEKEVRAWTFKRGMKAPQAAGIIHSDFEKGFIRAVTMSYED
                     LVKYGSEKAVKEAGRLREEGKEYIVQDGDIMEFRFNV"
     gene            10408..10977
                     /gene="pth"
                     /locus_tag="ACL29Z_001483"
     CDS             10408..10977
                     /gene="pth"
                     /locus_tag="ACL29Z_001483"
                     /EC_number="3.1.1.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000163933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004045 - aminoacyl-tRNA hydrolase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aminoacyl-tRNA hydrolase"
                     /protein_id="HGR0069770.1"
                     /translation="MTKLLVGLGNPGDKYFETKHNVGFMLIDQLAKKQNVTFTHDKIF
                     QADLASFFLNGEKIYLVKPTTFMNESGKAVHALLTYYGLDIDDLLIIYDDLDMEVGKI
                     RLRAKGSAGGHNGIKSIIQHIGTQVFNRVKIGIGRPKNGMSVVHHVLSKFDRDDYIGI
                     LQSVDKVDDSVNYYLQEKNFEKTMQRYNG"
     gene            10978..14487
                     /gene="mfd"
                     /locus_tag="ACL29Z_001484"
     CDS             10978..14487
                     /gene="mfd"
                     /locus_tag="ACL29Z_001484"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000258090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003684 - damaged DNA binding [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transcription-repair coupling factor"
                     /protein_id="HGR0069771.1"
                     /translation="MVTLLDLFSENDQIKKWHQNLTDKKRQLILGLSTSTKALAIASG
                     LEKEDRIVLLTSTYGEAEGLVSDLISILGEELVYPFLVDDAPMVEFLMSSQEKIISRV
                     EALRFLTDSSKKGILVCNIAASRLILPSPNAFKDSIVKISVGEEYDQHAFIHQLKENG
                     YRKVTQVQTQGEFSLRGDILDIFEISQLEPCRIEFFGDEIDGIRSFEVETQLSKENKT
                     ELTIFPASDMLLREKDYQRGQSALEKQISKTLSPILKSYLEEILSSFHQKQSHADSRK
                     FLSLCYDKTWTVFDYIEKDTPIFFDDYQKLMNQYEVFERDLAQYFTEELQNSKAFSDM
                     QYFSDIEQIYKKQSPVTFFSNLQKGLGNLKFDKIYQFNQYPMQEFFNQFSFLKEEIER
                     YKKMDYTIILQSSNSMGSKTLEDMLEEYQIKLDSRDKTSICKESVNLIEGNLRHGFHF
                     VDEKILLITEHEIFQKKLKRRFRRQHVSNAERLKDYNELEKGDYVVHHIHGIGQYLGI
                     ETIEIKGIHRDYVSVQYQNGDQISIPVEQIHLLSKYISSDGKVPKLNKLNDGHFKKAK
                     QKVKNQVEDIADDLIKLYSERSQLKGFAFSADDDDQDAFDDAFPYVETDDQLRSIEEI
                     KRDMQASQPMDRLLVGDVGFGKTEVAMRAAFKAVNDHKQVVILVPTTVLAQQHYTNFK
                     ERFQNFAVNVDVLSRFRSKKEQTATLEKLKNGQVDILIGTHRVLSKDVVFADLGLMII
                     DEEQRFGVKHKETLKELKKQVDVLTLTATPIPRTLHMSMLGIRDLSVIETPPTNRYPV
                     QTYVLEKNDSVIRDAVLREMERGGQVYYLYNKVDTIVQKVSELQELIPEASIGYVHGR
                     MSEVQLENTLLDFIEGQYDILVTTTIIETGVDIPNANTLFIENADHMGLSTLYQLRGR
                     VGRSNRIAYAYLMYRPEKSISEVSEKRLEAIKGFTELGSGFKIAMRDLSIRGAGNLLG
                     KSQSGFIDSVGFELYSQLLEEAIAKRNGNANANTRTKGNAELILQIDAYLPDTYISDQ
                     RHKIEIYKKIRQIDNRVNYEELQEELIDRFGEYPDVVAYLLEIGLVKSYLDKVFVQRV
                     ERKDNKITIQFEKVTQRLFLAQDYFKALSVTNLKAGIAENKGLMELVFDVQNKKDYEI
                     LESLLIFGESLLEIKESKEENSI"
     gene            14545..14811
                     /locus_tag="ACL29Z_001485"
     CDS             14545..14811
                     /locus_tag="ACL29Z_001485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001234972.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding S4 domain-containing protein"
                     /protein_id="HGR0069772.1"
                     /translation="MRLDKYLKVSRIIKRRTVAKEVADKGRIKVNGILAKSSTDLKVN
                     DQVEIRFGNKLLLVKVLEMKDSTKKEDAAGMYEIISETRVEENV"
     gene            14804..15172
                     /locus_tag="ACL29Z_001486"
     CDS             14804..15172
                     /locus_tag="ACL29Z_001486"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397271.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0051301 - cell division [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="septum formation initiator family protein"
                     /protein_id="HGR0069773.1"
                     /translation="MSKNIVQLNNSFIQNEYQRRRYLMKERQKRNRFMGGVLILIMLL
                     FILPTFNLAQSYQQLLQRRQQLADLQTQYQTLSDEKDKETAFATRLKDEDYAAKYTRA
                     KYYYSKSREKVYTIPDLLQR"
     gene            15177..15299
                     /locus_tag="ACL29Z_001487"
     CDS             15177..15299
                     /locus_tag="ACL29Z_001487"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000429331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SP_0009 family protein"
                     /protein_id="HGR0069774.1"
                     /translation="MENLLDVIEQFLSLSDEKLEELADKNQLLRLQEEKERKNA"
     gene            15292..16560
                     /locus_tag="ACL29Z_001488"
     CDS             15292..16560
                     /locus_tag="ACL29Z_001488"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001224749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="serine hydrolase"
                     /protein_id="HGR0069775.1"
                     /translation="MRKFLIILLLPSFLTISKVVSTEKEVVYTSKEIYYLSQSDFGIY
                     FREKLSSPMVYGEVPVYANEDLVVESGKLTPKTSFQITEWRLNKQGIPVFKLSNHQFI
                     AADKRFLYDQSEVTPTIKKAWLESDFKLYNSPYDLKEVKSSLSAYSQVSIDKTMFVEG
                     REFLHIDQAGWVAKESTSEEDNRMSKVQEMLSEKYQKDSFSIYVKQLTTGKEAGINQD
                     EKMYAASVLKLSYLYYTQEKINEGLYQLDTTVKYVSAVNDFPGSYKPEGSGSLPKKED
                     NKEYSLKDLITKVSKESDNVAHNLLGYYISNQSDATFKSKMSAIMGDDWDPKEKLISS
                     KMAGKFMEAIYNQNGFVLESLTKTDFDSQRIAKGVSVKVAHKIGDADEFKHDTGVVYA
                     DSPFILSIFTKNSDYDTISKIAKDVYEVLK"
     gene            16557..17834
                     /gene="tilS"
                     /locus_tag="ACL29Z_001489"
     CDS             16557..17834
                     /gene="tilS"
                     /locus_tag="ACL29Z_001489"
                     /EC_number="6.3.4.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016879 - ligase activity, forming
                     carbon-nitrogen bonds [Evidence IEA];
                     GO_process: GO:0008033 - tRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA lysidine(34) synthetase TilS"
                     /protein_id="HGR0069776.1"
                     /translation="MRESDFLNHFLKKGYFKKHAKAVLALSGGLDSMFLFKVLSTYQK
                     ELEIELILAHVNHKQRIESDWEEKELRKLAAEAELPIYISNFSGEFSEARARNFRYDF
                     FQEVMKKTGATALVTAHHADDQVETILMRLIRGTRLRYLSGIKEKQVVGEIEIIRPFL
                     HFQKKDFPSIFHFEDTSNQENHYFRNRIRNSYLPELEKENPRFRDAILGIGNEILDYD
                     LAIAELSNNINVEDLQQLFSYSESTQRVLLQTYLNRFPDLNLTKAQFAEVQQILKSKS
                     QYRHPIKNGYELIKEYQQFQICKISPQADEKEDELVLHYQNQVAYQGYLFSFGLPLEG
                     ESIQQIPVSRETSIHIRHRKTGDVLIQNGHRKKLRRLFIDLKIPMEKRNSALIIEQFG
                     EIVSILGIATNNLSKKTKNDIMNTVLYIEKIDR"
     gene            17838..18380
                     /gene="hpt"
                     /locus_tag="ACL29Z_001490"
     CDS             17838..18380
                     /gene="hpt"
                     /locus_tag="ACL29Z_001490"
                     /EC_number="2.4.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006166 - purine ribonucleoside salvage
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="hypoxanthine phosphoribosyltransferase"
                     /protein_id="HGR0069777.1"
                     /translation="MLENDIKKVLVSHDEITEAAKKLGAQLTKDYAGKNPILVGILKG
                     SIPFMAELVKHIDTHIEMDFMMVSSYHGGTASSGVINIKQDVTQDIKGRHVLFVEDII
                     DTGQTLKNLRDMFKAREAASVKIATLLDKPEGRVVEIEADYTCFTIPNEFVVGYGLDY
                     KENYRNLPYIGVLKEEVYSN"
     gene            18396..>20349
                     /gene="ftsH"
                     /locus_tag="ACL29Z_001491"
     CDS             18396..>20349
                     /gene="ftsH"
                     /locus_tag="ACL29Z_001491"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000744538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0004222 - metalloendopeptidase activity
                     [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA];
                     GO_process: GO:0051301 - cell division [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent zinc metalloprotease FtsH"
                     /protein_id="HGR0069778.1"
                     /translation="MKKQNNGLIKNPFLWLLFIFFLVTGFQYFYSGNNSGGSQQINYT
                     ELVQEITDGNVKELTYQPNGSVIEVSGVYKNPKTSKEETGIQFFTPSVTKVEKFTSTI
                     LSADTTVSELQKLATDHKAEVTVKHESSSGIWINLLVSIVPFGILFFFLFSMMGNMGG
                     GNGRNPMSFGRSKAKAANKEDIKVRFSDVAGAEEEKQELVEVVEFLKDPKRFTKLGAR
                     IPAGVLLEGPPGTGKTLLAKAVAGEAGVPFFSISGSDFVEMFVGVGASRVRSLFEDAK
                     KAAPAIIFIDEIDAVGRQRGVGLGGGNDEREQTLNQLLIEMDGFEGNEGIIVIAATNR
                     SDVLDPALLRPGRFDRKVLVGRPDVKGREAILKVHAKNKPLAEDVDLKLVAQQTPGFV
                     GADLENVLNEAALVAARRNKSIIDASDIDEAEDRVIAGPSKKDKTVSQKERELVAYHE
                     AGHTIVGLVLSNARVVHKVTIVPRGRAGGYMIALPKEDQMLLSKEDMKEQLAGLMGGR
                     VAEEIIFNVQTTGASNDFEQATQMARAMVTEYGMSEKLGPVQYEGNHAMLGAQSPQKS
                     ISEQTAYEIDEEVRSLLNEARNKAAEIIQSNRETHKLIAEALLKYETLDSTQIKALYE
                     TGKMPEAVEEESHALSYDEVKSKMNDE"
BASE COUNT         7037 a         3286 c         3780 g         6246 t
ORIGIN      
        1 taaattacaa gataaaaaat ctatttttag acatatagtc taatttgttt acaaggagga
       61 aatatgcaag aaagtaacaa acgcttaaaa acaaagcgaa ctattgaaaa tgctatggta
      121 caattactga tggaacagcc atttgataaa atttctactg tcaaattagt agaaaaagcc
      181 ggaattagtc gttccagctt ctatactcac tataaggata agtatgatat gattgagcac
      241 tatcaaagca agctattcca tacatttgaa tatatttttc aaaaacatgc tcatcacaaa
      301 agagacgcta ttttagaagt ttttgaatat ctagagtcag aaccacttct ggctgccctt
      361 ctttctgaaa atgggactaa agaaatccaa aatttcttac gaaataaact tcatatcatg
      421 cttagtacag atttacaaaa gcgatttatg caactgaatc taaataccac tgaattagaa
      481 tatagtagca tctatctaac tcatgcactt tttggtgtct gccaaacttg gattgcacat
      541 ggaaaaaaag aaagttctca agaaataaca gacttcctta tgaaaatgct tggtgataca
      601 aattgataca aaaagaggaa cacagctgtg ttccctttta tctatactcc gccagtagga
      661 ctcgaaccta cgacatcatg attaacagtc atgcgctact accaactgag ctatggcgga
      721 taaaatagtc cgtacgggat tcgaacccgt gttaccgccg tgaaaaggcg gtgtcttaac
      781 cccttgacca acggaccttc tatctgtagc agatataacc attatatcaa tttcttgcta
      841 attgtcaatc acttttgaga ttttttctct aaaatatctt ttaattttct aatttttaat
      901 cttgaaatag gacaacgatg gtcttcatag aaaacaattt ctaagttttt tcgatcaatt
      961 tctctgatat tgcctatatt taccaaaaat gacttgtgag gagaataaaa tcgctgagta
     1021 tgtttgtcct tttcctgaat atctgtcatg gtaccataaa actcttttgc aaaattctta
     1081 ccaataatgc gcaatttatg agatacccct gttgtttcaa tatacaaaat atcatggtaa
     1141 ggaattttta aatcatttcc cttgtaattg tagtcgaaat aatctacaac atcttcattt
     1201 tcaagtaaca tactcttcgt gtagaagata ttttgctcaa ttctcttctt aaacatctca
     1261 tcattgatat ccttatcaac aaaatctagg gctgatacct ggtatttata ggttagagtc
     1321 gcaaactctg atcgactagt gataaagacg ataatagcgt aaggattgta atgacgaatg
     1381 agctgagcca cttcaaatcc ctttttctca attccatgaa tatcgatatc taggaaataa
     1441 agctgattta cttcatcatt ttcaatgtat tcttcaaatt cacggacttt tcccgttgtc
     1501 ttgtatgata ttggaatatt cgattctttc gaaatttcat ccaatattct ctctagtctc
     1561 acttgatgtt caataacatc ttctaaaatt aaaactttca ttcaaattcc ctcttaaatc
     1621 taatgatttg tctaaatgta ctgccttcca tctctgtttc taaaataata ttgttgtact
     1681 tatctagtag ttctttcaca ttatttaatc cgactccgcg atttcttccc ttagtggaga
     1741 atcctaaggc aaatagatct cctgaaggag tcatcgtcat tttacatgaa ttctgaatca
     1801 caataactgt ttcagtttcc atcttaataa ctgctacttc catctgcttt ttatagctat
     1861 cagccgatcc ttcgacagca ttattcaata aaacgctcat gatacgaacc aaatccaata
     1921 gttcaattgg aagcttggta atcgtatctt ttacttccag tgtaaactct acaccattat
     1981 ttcgagcata gacaattgac tgagcaacca aacttcgtaa agctgagtct tctatgttgt
     2041 tcaaatcaaa gtaagtgtac ttatctgaac gcaatttatg atttgctttg actaaaactt
     2101 cattgtaaat tctgtcaatt tcctgtaaat taccactgtc aattgccatc tgcatgctga
     2161 caagcattcc agcataatca tgtcgaaaac cacggatttc attatacaga ccaacaattt
     2221 catctgtgta attctgtaaa tgtttctgtt caaatttctt ctgcttcaaa gcaatctctt
     2281 tctccatttg aactttatga gaattcattg caaagaaggt caaaaggaga gagataaaga
     2341 caatagatga caaaatactt ccaaaactat tcaaatgttt aatcgtactt accatatctg
     2401 aaacgaaaga tacaatatgt agcaatagta aagcaaaaaa tacttttttc aagaaaggat
     2461 aaaggtagtc ctcgtcaaaa taggctagtt ccaaatggaa atagtaaatg atttttaatg
     2521 taacaaaata ggttaacacc gtcacaacga aaaagaatgg gaaatgatat tgtaaaacaa
     2581 aattatctcc tgttatagag gagaaagtta cggacagaaa gttatgagtg ctctcatata
     2641 aaagagatag tagtaaactt aggaatagtc ctctatccct ctcatactgt ttcatccatc
     2701 gaaaatagga atataatccc aaaggaaata aaaatctttc aatccctaac ccatctaaat
     2761 atagaatata taagggaaaa tcaaatacta tttctgttag taatgtataa gcaccaaaaa
     2821 cgaataattc ttttctattt atttgacctt tacaaataaa atggtaactg tgactaataa
     2881 ttaaaaaatg aacaataacc gtcccaaatc caaataaatc cattactctt tccccttatt
     2941 tcattacttt tttctttgta aaataaaatc acggaagaat tttgacaacc tcatctcccc
     3001 acctttaatc ttttgtaagt ctttttcctt caaagctaca aactgttcca atttaactgt
     3061 gtttttcata ataaaatctc ctaaaatgtt ttttcttgta agctaactta caaaaaccat
     3121 tatacaaaat ggaatttcgt tttagataaa attctctcaa ctgtcatttt tttctcccaa
     3181 agtgtacttt tttaagaaaa aagccgggaa aattcccagc tttgctatta tattgatccc
     3241 agcaggattc gaacctgcga ccgttcgctt agaaggcgaa tgctctatcc agctgagcta
     3301 tgagacctaa tacaattatt ctaccaaaaa ttcaattaaa agtcaatttt ctatttatgg
     3361 taggggaatc cctgctgaat cgtaaaagcg cgatagattt gttcaacaag aactagtctc
     3421 attaactgat ggggtaaggt taggcgacca aaactgacag aaagattggc tctatttttt
     3481 acagatgatg acaatcctaa acttccccca ataataaaag taagagtaga aaatcctttt
     3541 atagaagttt cttctaactg cttactaaat tcttctgaga agaaagtttt cccttcaatg
     3601 gctaacacaa taacgaaatc acggtcagca atttttgata aaattctctg accttctatt
     3661 tctaaaatct tttgattttc tgattcactg gccttatctg gtgttttttc atctgataac
     3721 tcaatcattt caaacttagc aaatctagaa attcgttttg aatactctgc gataccatct
     3781 tttaaatact tttctttcag tttcccaact gttacaactt taattttcat gactctattc
     3841 taacatattc tctatttttt cacatcttat tcacaaaata aaaaatagat ttcaattaag
     3901 aaaatcacag tttcaaaaga gttatccaca gtttgtgtaa aacttttgtg tttaagttat
     3961 aattaagcta gtcagtttat actttcagta attcaaacat atggaggcaa atatgaaaca
     4021 tctaaaaaca ttttacaaaa aatggtttca attattagtc gttatcgtca ttagcttttt
     4081 tagtggagcc ttgggtagtt tttcaataac tcaactaact caaaaaagta gtgtaaacaa
     4141 ctctaacaac aatagtacta ttacacaaac tgcctataag aacgaaaatt caacaacaca
     4201 ggctgttaac aaagtaaaag atgctgttgt ttctgttatt acttattcgg caaacagaca
     4261 aaatagcgta tttggcaatg atgatactga cacagattct cagcgaatct ctagtgaagg
     4321 atctggagtt atttataaaa agaatgataa agaagcttac atcgtcacca acaatcacgt
     4381 tataaatggc gccagcaaag tagatattag attgtcagat gggactaaag tacctggaga
     4441 aattgtcgga gctgacactt tctctgatat tgctgtcgtc aaaatctctt cagaaaaagt
     4501 gacaacagta gctgagtttg gtgattctag taagttaact gtaggagaaa ctgctattgc
     4561 catcggtagc ccgttaggtt ctgaatatgc aaatactgtc actcaaggta tcgtatccag
     4621 tctcaataga aatgtatcct taagatcgga agatggacaa gctatttcta caaaagccat
     4681 ccaaactgat actgctatta acccaggtaa ctctggcggc ccactgatca atattcaagg
     4741 gcaggttatc ggaattacct caagtaaaat tgctacaaat ggaggaacat ctgtagaagg
     4801 tcttggtttc gcaattcctg caaatgatgc tatcaatatt attgaacagt tagaaaaaaa
     4861 cggaaaagtg acgcgtccag ctttgggaat ccagatggtt aatttatcta atgtgagtac
     4921 aagcgacatc agaagactca atattccaag taatgttaca tctggtgtag ttgttcgttc
     4981 ggtacaaagt aatatgcctg ccaatggtca ccttgaaaaa tacgatgtaa ttacaaaagt
     5041 agatgacaaa gagattgctt catcaacaga cttacaaagt gctctttaca accattctat
     5101 cggagacacc attaagataa cctactatcg taacgggaaa gaagaaacta cctctatcaa
     5161 acttaacaag agttcaggtg atttagaatc ttgattgaca tctatgtaaa gaaagcttta
     5221 cataagagaa aagatgtgtt agtgtagaat catggaaaaa tttgaaatga tttctatcac
     5281 agatatacaa aaaaatccct atcaaccccg aaaagaattt gatagagaaa aactagatga
     5341 actagcacag tctatcaaag aaaatggggt cattcaaccg attattgttc gtcaatctcc
     5401 tgttattggt tatgaaatcc ttgcaggaga gagacgctat cgggcttcac ttttagctgg
     5461 tctacggtct atcccagctg ttgttaaaca gatttcagac caagagatga tggtccagtc
     5521 cattattgaa aatttacaga gagaaaattt aaacccaata gaagaagcac gcgcctatga
     5581 atctctcgta gagaaaggat tcacccatgc tgaaattgca gataagatgg gcaagtctcg
     5641 tccatatatc agcaactcca ttcgtttact ttccttgcca gaacagattc tttcagaagt
     5701 agaaaatggc aaactatcac aagcccatgc gcgttcccta gttgggttaa ataaggaaca
     5761 acaagactat ttctttcaac ggattataga agaagatatt tctgtaagga aattagaagc
     5821 tcttctgaca gagaaaaaac aaaagaaaca gcaaaaaact aatcatttca tacaaaatga
     5881 agaaaaacag ttaagaaaac tactcggatt agatgtagaa attaaactat ctaaaaaaga
     5941 cagtggaaaa atcattattt ctttttcaaa tcaagaagaa tatagtagaa ttatcaacag
     6001 cctgaaataa ggctgttctt ttattttttt atctcacaag gttatccact atgtttttcg
     6061 ataaaaagct taataaatca ataatttctt cttttatccc caacctgtgg ataaagtttg
     6121 gtaacattgt ggattatttt tcacagcttg tggaaaattc ttgctatcta tggtaaaata
     6181 tctctagtat taaactttta aatagtaaag gaggagaaag gattgaaaga aaaacaattt
     6241 tggaatcgta tattagaatt tgcacaagaa agactgactc gatccatgta tgatttctat
     6301 gctattcaag ctgaactcat caaggtagag gaaaatgttg ccactatatt tctacctcgc
     6361 tctgaaatgg aaatggtctg ggaaaaacaa ctaaaagata ttattgtagt agctggtttt
     6421 gaaatttatg acgctgaaat aactccccac tatattttca ccaaacctca agatacgact
     6481 agctcacaag ttgaagaagc tacaaattta actctttata actatagtcc aaagttagta
     6541 tctattcctt attcagatac gggattaaaa gaaaagtata cctttgataa ctttattcaa
     6601 ggggatggaa atgtttgggc tgtatcagcc gctttagctg tctctgaaga tttggctctg
     6661 acctataacc ctctttttat ctatggagga ccaggccttg gtaagactca cttattaaac
     6721 gctattggaa atgaaattct aaaaaatatt cctaatgcgc gtgttaaata tatccctgcc
     6781 gaaagcttta ttaatgactt tcttgatcac ctaagacttg gggaaatgga aaagtttaaa
     6841 aagacctatc gtagtcttga tcttttgtta atcgatgata ttcagtcact cagcggaaaa
     6901 aaagttgcaa ctcaggaaga atttttcaat acctttaacg cccttcatga caagcaaaaa
     6961 cagattgtcc taacgagtga tcgtagtcca aaacatctag aagggctcga ggagaggctt
     7021 gtcacgcgtt ttagttgggg attgacacaa actatcacac cccctgactt tgaaacacgt
     7081 attgccattt tacaaagtaa aacggaacat ttaggctaca atttccaaag tgatactcta
     7141 gaatacctag ctgggcaatt tgattcaaat gttcgagatc ttgagggagc catcaacgac
     7201 atcactttaa ttgccagagt aaaaaaaatc aaggatatca ctattgatat tgctgcagaa
     7261 gccattagag cccgcaaaca agatgttagc caaatgctcg tcatcccaat tgataaaatc
     7321 caaactgaag ttggtaactt ttatggtgtt agtatcaaag aaatgaaggg aagtagacgc
     7381 cttcaaaata ttgttttggc ccgtcaagta gccatgtatt tatctagaga actaacagat
     7441 aatagtcttc caaaaattgg gaaggaattt gggggaaaag atcataccac agtcattcat
     7501 gcccatgcca aaataaaatc tttgattgat caagacgata atttacgttt agaaattgaa
     7561 tcaatcaaaa agaaaatcaa ataatttgtg gataactttt agttttttat cttttttatc
     7621 cacatttttt aaacaagcta aaaaacttga tatgacttgt ttaaaggctg ttttccacag
     7681 atttcacaga ctctattatt actattatct ttctaatact aaaaataaat aaaggagaat
     7741 ccatgattca tttttcaatt aataaaaatt tatttctaca agcattaaat actactaaga
     7801 gagctattag ttctaaaaat gccattccta ttttatcaac agtaaaaatt gacgtgacca
     7861 atgaaggtat tactttaatt ggttcaaatg gtcaaatttc aattgaaaat tttatttctc
     7921 aaaaaaatga agatgctggt ttgttaatta cttctttagg ttcgatcctt cttgaagctt
     7981 ctttctttat caatgtagta tctagtttac ctgatgtaac tcttgatttt aaagaaattg
     8041 aacaaaatca aattgtttta accagtggca aatcagaaat taccctaaaa ggaaaagata
     8101 gcgaacaata tccacgaatc caagaaattt cagcaagcac tcctttaata cttgaaacaa
     8161 aattactcaa gaaaattatt aatgaaacag cctttgctgc aagtacacaa gagagtcgtc
     8221 cgattttaac aggtgtccac ttcgtattga gtcaacacaa agagttaaaa acagttgcaa
     8281 cagactctca tcgcctaagc cagaaaaaat tgactcttga aaaaaatagt gatgattttg
     8341 atgtcgtaat tcctagccgt tctctacgcg aattttcagc ggtatttaca gatgatatcg
     8401 aagctgtaga gattttcttt gccaataacc aaatcctctt tagaagcgaa aatattagct
     8461 tctatactcg tctcctagaa ggaaactatc ctgatacaga tcgcttgatt ccaacagact
     8521 ttaacactac tattactttt aatgtggtaa acttacgcca gtcaatggag cgtgcccgtc
     8581 ttttatcaag tgcgactcaa aatggtactg tgaaacttga aattaaggat ggggttgtta
     8641 gcgcccatgt tcactctcca gaagttggta aagtaaacga agaaatcgat actgatcagg
     8701 ttactggtga agatttgacc attagtttca acccaactta cttgattgat tctcttaaag
     8761 ctttaaatag cgaaaaggtg accattagct ttatctcagc tgttcgtcca tttactcttg
     8821 tgccagcaga tactgacgaa gacttcatgc aactcattac accagttcgt acaaattaag
     8881 tgaaagaggt tgagcctggc tcgcctcttt tatgatataa tcgaaaaaga aaaggagagt
     8941 agtatgtatc aagttggaaa ttttgttgag atgaaaaaat cacacgcttg tacaatcaag
     9001 tcgactggta aaaaggctaa tcgttgggaa attacacgtg taggagcaga tatcaaaata
     9061 aaatgcagta attgtgagca tgttgtcatg atggggcgat atgattttga gcgaaaaatg
     9121 aataaaatta ttgactgaga acccttagtt agagggttag cactttatcc ctttttgtgt
     9181 tataatatta gggattgaaa tgaaaacgga gaatgagaaa tatggctttg acagcaggta
     9241 tcgttggttt gccaaacgtt ggtaaatcaa cactatttaa tgcaattaca aaagcaggag
     9301 cagaggcagc aaactaccca tttgcgacta ttgatccaaa tgttggaatg gtggaagttc
     9361 cagatgaacg cctacaaaaa ctaactgaaa tgataactcc taaaaagaca gttcccacaa
     9421 catttgaatt tacagatatt gcagggattg taaaaggagc ttcaaaagga gaagggctag
     9481 ggaataaatt cttggccaat attcgtgaag tagatgcgat tgttcacgta gttcgtgctt
     9541 ttgatgatga aaatgtaatg cgcgagcaag gacgtgaaga cgcctttgta gatccacttg
     9601 cagatattga tacaattaat ctggaattaa ttcttgctga cttagaatca gtgaacaaac
     9661 gatatgcgcg tgtagaaaag atggcacgta cgcaaaaaga taaagaatca gtagcagaat
     9721 tcaatgttct tcaaaagatt aaaccagtcc tagaagacgg gaaatcagct cgtatcattg
     9781 aatttacaga tgaggaacaa aaggttgtca aaggtctttt ccttttgacg actaaaccag
     9841 ttctttatgt agctaatgtg gacgaggatg tggtttcaga acctgactct atcgactatg
     9901 tcaaacaaat tcgtgaattt gcagcgacag aaaatgctga agtagtcgtt atttctgcgc
     9961 gtgctgagga agaaatttct gaattggatg atgaagataa aaaagagttt cttgaagcca
    10021 ttggtttgac agaatcaggt gtagataagt tgacgcgtgc agcttaccac ttgcttggat
    10081 tgggaactta cttcacagct ggtgaaaaag aagttcgcgc ttggactttc aaacgtggta
    10141 tgaaggctcc tcaagcagct ggtattatcc actcagactt tgaaaaaggc tttattcgtg
    10201 cagtaaccat gtcatatgaa gatctagtga aatacggatc tgaaaaggcc gtaaaagaag
    10261 ctggacgctt gcgtgaagaa ggaaaagaat atatcgttca agatggcgat atcatggaat
    10321 tccgctttaa tgtctaaaaa ttaataaatg gtgtcaatta ggttggaaaa aaattccaac
    10381 ccttttggct tttgaaagga aaaataaatg accaaattac ttgtaggctt gggaaatcca
    10441 ggggataaat attttgaaac aaaacacaat gttggtttta tgttgattga tcaactagcg
    10501 aagaaacaga atgtcacttt tacacacgat aagatatttc aagctgacct agcatccttt
    10561 ttcctaaatg gagaaaaaat ttatctggtt aaaccaacga cctttatgaa tgaaagtgga
    10621 aaagcagttc atgctttatt aacttactat ggtttggata ttgacgattt acttatcatt
    10681 tacgatgatc ttgacatgga agttgggaaa attcgtttaa gagcaaaagg ctcagcaggt
    10741 ggtcataatg gtatcaagtc tattattcaa catataggaa ctcaggtctt taaccgtgtt
    10801 aagattggaa ttggaagacc taaaaatggt atgtcagttg ttcatcatgt tttgagtaag
    10861 tttgacaggg atgattatat cggtatttta cagtctgttg acaaagttga cgattctgta
    10921 aactactatt tacaagagaa aaattttgag aaaacaatgc agaggtataa cggataaatg
    10981 gtgaccttat tagatttatt ctcagaaaat gatcagatta aaaaatggca tcaaaattta
    11041 acagataaga aaagacaact aatacttggt ttatcaacat ctactaaggc gcttgcaatt
    11101 gcaagcggtt tagaaaaaga agataggatt gtgttattga cgtcaactta tggagaagca
    11161 gaaggacttg ttagtgatct tatatctatc ttgggtgagg aactcgtcta tccatttttg
    11221 gtagatgatg ctcctatggt ggagtttttg atgtcttcac aggaaaaaat tatttcacgg
    11281 gttgaagcct tgcgtttttt gactgattca tctaagaaag ggattttagt ttgtaatatc
    11341 gcagcaagtc gattgatttt accgtctccc aatgcattca aagatagtat tgtaaaaatc
    11401 tcagttggtg aagaatatga tcaacacgcg tttatccatc agttaaagga aaatggctat
    11461 cgaaaagtta ctcaagtaca aactcagggc gaatttagtc ttcgaggaga tattttagat
    11521 atttttgaaa tatcccagtt agaaccttgt cgaattgagt tttttggtga tgaaattgat
    11581 ggtatcaggt catttgaagt agaaacacaa ttatcgaaag aaaataagac agaactcact
    11641 atctttccag ctagtgatat gcttttgaga gaaaaggatt atcaacgagg acagtcagct
    11701 ttagaaaaac aaatttcaaa aactttatca cctattttga aatcatacct agaagaaatt
    11761 ctttcaagtt ttcatcaaaa gcaaagtcat gcagattctc ggaagttttt atctttgtgc
    11821 tatgataaga catggactgt ctttgattat attgaaaaag atactccaat attctttgat
    11881 gattatcaaa aattgatgaa tcagtatgaa gtatttgaaa gagacttagc gcagtacttt
    11941 acagaagaat tacagaatag taaagcattt tctgatatgc agtatttttc tgatattgaa
    12001 caaatctata aaaaacaaag tccagtgacc tttttttcta atcttcaaaa gggtttagga
    12061 aatctcaaat ttgacaaaat ttatcaattc aatcaatatc ctatgcagga atttttcaat
    12121 cagttttctt ttctaaaaga agaaattgaa cgatataaaa aaatggatta caccattatt
    12181 ctgcagtcta gcaattcaat gggaagtaaa acattggagg atatgttaga ggaatatcag
    12241 attaaattgg attctagaga taagacaagt atctgtaaag aatctgtaaa cttaatagag
    12301 ggtaatctca gacatggttt tcattttgta gatgaaaaga ttttattgat aactgaacat
    12361 gagatttttc aaaagaaatt aaagcgtcgt tttcgaagac aacatgtttc aaatgcagag
    12421 agattaaaag attacaatga acttgaaaaa ggggactatg ttgtccatca tatccatggg
    12481 attggtcaat atctaggaat tgaaaccatt gaaatcaagg gaattcatcg cgattatgtc
    12541 agtgtccaat accaaaatgg tgatcaaatt tctattcccg tggaacagat tcatctactg
    12601 tccaaatata tttcaagtga tggtaaagtt ccaaaactca ataaattaaa tgatggtcat
    12661 tttaaaaagg ccaagcaaaa ggttaagaac caggtagagg atatagctga tgatttaatc
    12721 aaactctact ctgaacgtag tcagttgaag ggttttgctt tctcagctga tgatgatgat
    12781 caagatgcct ttgatgatgc tttcccttat gttgaaacgg atgatcaact tcgtagtatt
    12841 gaggaaatca agagggatat gcaggcttct cagccaatgg atcgactttt agttggggat
    12901 gttggttttg gaaagactga agttgctatg cgtgcagcct ttaaagcagt caatgatcac
    12961 aaacaggttg tcattctagt tccgacgacg gttttagcgc aacagcacta tacgaatttt
    13021 aaggaacgat tccaaaattt tgcagttaat gttgatgtgt tgagtcgctt tagaagtaaa
    13081 aaagagcaga ctgcaacact tgaaaaattg aaaaacggtc aagtcgatat tttgattgga
    13141 acacatcgtg ttttgtcaaa agatgttgtg tttgctgatt tgggcttgat gattattgat
    13201 gaggaacagc gatttggtgt caagcataag gaaactttga aagaactgaa gaaacaagtg
    13261 gatgtcctaa ccttgaccgc tacgccaatc cctcgtaccc tccatatgtc tatgctggga
    13321 atcagagatt tgtctgttat tgaaactccg ccgactaatc gctatcctgt tcagacctat
    13381 gttttggaaa agaatgatag tgtcattcgt gatgctgtct tgcgtgaaat ggagcgtgga
    13441 ggtcaagttt actatcttta caacaaagtt gacacaattg ttcagaaggt ttcagaatta
    13501 caggagttga ttccggaggc ttcgattgga tatgttcatg gtcgaatgag tgaagtccag
    13561 ttggaaaata ctctattaga ctttattgag ggacaatacg atatcttggt gacgactact
    13621 attattgaga caggggtgga cattccaaat gctaatactt tatttattga aaatgcggac
    13681 catatgggct tgtcaacctt atatcagtta agaggaagag tcggtcgtag taatcgtatt
    13741 gcttatgctt atctcatgta tcgtccagaa aaatcaatca gtgaagtctc tgaaaagaga
    13801 ttagaagcga ttaaaggatt tacagaattg ggctctggct ttaagattgc aatgcgagat
    13861 ctttcgattc gtggagcagg aaatctttta ggaaaatccc agtctggttt cattgattct
    13921 gttggttttg aattgtattc gcagttatta gaggaagcta ttgctaaacg aaacggtaat
    13981 gctaacgcta acacaagaac caaagggaat gctgagttga ttttgcaaat tgatgcctat
    14041 cttcctgata cttatatttc tgatcaacga cataagattg aaatttacaa gaaaattcgt
    14101 caaattgaca accgtgtcaa ttatgaagag ttacaagagg agttgataga ccgttttgga
    14161 gaatacccag atgtagtagc ctatctttta gagattggtt tggttaaatc atacttggac
    14221 aaggtctttg ttcaacgtgt ggaaagaaaa gataataaaa ttacaattca atttgaaaaa
    14281 gtcactcaac gactgttttt agctcaagat tattttaaag ctttatccgt aacgaactta
    14341 aaagcaggca tcgctgagaa taagggatta atggagcttg tatttgatgt ccaaaataag
    14401 aaagattatg aaattttaga aagtttgctg atttttggag aaagtttatt agaaataaaa
    14461 gagtctaagg aagaaaattc catttgatat ttttcttcta taaaatagat aaaaatggta
    14521 caataataaa ttgaggtaat aaggatgaga ttagataaat atttaaaagt atcgcgaatt
    14581 atcaagcgtc gtacagtcgc aaaggaagta gcagataaag gtagaatcaa ggttaatgga
    14641 atcttggcca aaagttcaac ggacttgaaa gttaatgacc aagttgaaat tcgctttggc
    14701 aataagttgc tacttgtaaa agtactagag atgaaagata gtacaaaaaa agaagatgca
    14761 gcaggcatgt atgaaattat cagtgaaaca cgggtagaag aaaatgtcta aaaatattgt
    14821 acaattgaat aattctttta ttcaaaatga ataccaacgt cgtcgctacc tgatgaaaga
    14881 acgacaaaaa cggaatcgtt ttatgggggg ggtattgatt ttgattatgc tattatttat
    14941 cttgccaact tttaatttag cgcagagtta tcagcaatta ctccaaagac gtcagcaatt
    15001 agcagacttg caaactcagt atcaaacttt gagtgatgaa aaggataagg agacagcatt
    15061 tgctaccagg ttgaaagatg aagattatgc tgctaaatat acacgagcga agtactatta
    15121 ttctaagtcg agggaaaaag tttatacgat tcctgacttg cttcaaaggt gataaaatgg
    15181 aaaatttatt agacgtaata gagcaatttt tgagtttgtc agatgaaaag ctggaagaat
    15241 tggctgataa aaatcaatta ttgcgtttac aagaagaaaa ggaaaggaag aatgcgtaaa
    15301 ttcttaatta ttttgttgct accaagtttt ttgaccattt caaaagtcgt tagcacagaa
    15361 aaagaagtcg tctatacttc gaaagaaatt tattaccttt cacaatctga ctttggtatt
    15421 tattttagag aaaaattaag ttctcccatg gtttatggag aggttcctgt ttatgcgaat
    15481 gaagatttag tagtggaatc tgggaaattg actcccaaaa caagttttca aataaccgag
    15541 tggcgcttaa ataaacaagg aattccagta tttaagctat caaatcatca atttatagct
    15601 gcggacaaac gatttttata tgatcaatca gaggtaactc caacaataaa aaaagcatgg
    15661 ttagaatctg actttaaact gtacaatagt ccttatgatt taaaagaagt gaaatcatcc
    15721 ttatcagctt attcgcaagt atcaatcgac aagaccatgt ttgtagaagg aagagaattt
    15781 ctacatattg atcaggctgg atgggtagct aaagaatcaa cttctgaaga agataatcgg
    15841 atgagtaaag ttcaagaaat gttatctgaa aaatatcaga aagattcttt ctctatttat
    15901 gttaagcaac tgactactgg aaaagaagct ggtatcaatc aagatgaaaa gatgtatgca
    15961 gccagcgttt tgaaactctc ctatctctat tatacgcaag aaaaaataaa tgagggtctt
    16021 tatcagttag atacgactgt aaaatacgta tctgcagtca atgattttcc aggttcttat
    16081 aaaccagagg gaagtggtag tcttcctaaa aaagaagata ataaagaata ttctttaaag
    16141 gatttaatta cgaaagtatc aaaagaatct gataatgtag ctcataatct attgggatat
    16201 tacatttcaa accaatctga tgccacattc aaatccaaaa tgtctgccat tatgggagat
    16261 gattgggatc caaaagaaaa attgatttct tctaagatgg ccgggaagtt tatggaagct
    16321 atttataatc aaaatggatt tgtgctagag tctttgacta aaacagattt tgatagtcag
    16381 cgaattgcca aaggtgtttc tgttaaagta gctcataaaa ttggagatgc ggatgaattt
    16441 aagcatgata cgggtgttgt ctatgcagat tctccattta ttctttctat tttcactaag
    16501 aattctgatt atgatacgat ttctaagata gccaaggatg tttatgaggt tctaaaatga
    16561 gggaatcaga ttttttaaat cattttctca agaagggata tttcaaaaag catgctaagg
    16621 cggttctagc tctttctggt ggattagatt ctatgtttct atttaaggta ttgtctactt
    16681 atcaaaaaga gttagagatt gaattgattc tagctcatgt gaatcataag cagagaattg
    16741 aatcagattg ggaagaaaag gaattaagga agttggctgc tgaagcagag cttcctattt
    16801 atatcagcaa tttttcagga gaattttcag aagcgcgtgc acgaaatttt cgttatgatt
    16861 tttttcaaga ggtcatgaaa aagacaggtg cgacagcttt agtcactgcc caccatgctg
    16921 atgatcaggt ggaaacgatt ttgatgcgct tgattcgagg aactcgcttg cgctatctat
    16981 caggaattaa ggagaagcaa gtagtcggag agatagaaat cattcgtccc ttcttgcatt
    17041 ttcagaaaaa agactttcca tcaatttttc actttgaaga tacatcaaat caggagaatc
    17101 attattttcg aaatcgtatt cgaaactctt acttaccaga attggaaaaa gaaaatcctc
    17161 gatttaggga tgcaatctta ggcattggca atgaaatttt agattatgat ttggcaatag
    17221 ctgaattatc taacaatatt aatgtggaag atttacagca gttattttct tactctgagt
    17281 ctacacaaag agttttactt caaacttatc tgaatcgttt tccagatttg aatcttacaa
    17341 aagctcagtt tgctgaagtt cagcagattt taaaatctaa aagccagtat cgtcatccga
    17401 ttaaaaatgg ctatgaattg ataaaagagt accaacagtt tcagatttgt aaaatcagtc
    17461 cgcaggctga tgaaaaggaa gatgaacttg tgttacacta tcaaaatcag gtagcttatc
    17521 aaggatattt attttctttt ggacttccat tagaaggtga atcaattcaa caaatacctg
    17581 tttcacgtga aacatccata cacattcgtc atcgaaaaac aggagatgtt ttgattcaaa
    17641 atgggcatag aaaaaaactc agacgtttat ttattgattt gaaaatccct atggaaaaga
    17701 gaaactctgc tcttattatt gagcaatttg gtgaaattgt ctcaattttg ggaattgcga
    17761 ccaataattt gagtaaaaaa acgaaaaatg atataatgaa cactgtactt tatatagaaa
    17821 aaatagatag gtaaaaaatg ttagaaaacg atattaaaaa agtcctcgtt tcacacgatg
    17881 aaattacaga agcagctaaa aaactaggtg ctcaattaac taaagattat gcaggaaaaa
    17941 atccaatctt agttgggatt ttaaaaggat ctattccttt tatggctgaa ttggtcaaac
    18001 atattgatac acatattgaa atggacttca tgatggtttc tagctaccat ggtggaacag
    18061 caagtagtgg tgttatcaat attaaacaag atgtgactca agatatcaaa ggaagacatg
    18121 ttctatttgt agaagatatc attgatacag gtcaaacttt gaagaatttg cgagatatgt
    18181 ttaaagcaag agaagcagct tctgttaaaa ttgcaacctt gttggataaa ccagaaggac
    18241 gtgttgtaga aattgaggca gactatacct gctttactat cccaaatgag tttgtagtag
    18301 gttatggttt agactacaaa gaaaattatc gtaatcttcc ttatattgga gtattgaaag
    18361 aggaagtgta ttcaaattag aaagaataat ctttaatgaa aaaacaaaat aatggtttaa
    18421 ttaaaaatcc ttttctatgg ttattattta tctttttcct tgtgacagga ttccagtatt
    18481 tctattctgg gaataactca ggaggaagtc agcaaatcaa ctatactgag ttggtacaag
    18541 aaattaccga tggtaatgta aaagaattaa cttaccaacc aaatggtagt gttatcgaag
    18601 tttctggtgt ctataaaaat cctaaaacaa gtaaagaaga aacaggtatt cagtttttca
    18661 cgccatctgt tactaaggta gagaaattta ccagcactat tctttctgca gatactaccg
    18721 tatcagaatt gcaaaaactt gctactgacc ataaagcaga agtaactgtt aagcatgaaa
    18781 gttcaagtgg tatatggatt aatctactcg tatccattgt gccatttgga attctattct
    18841 tcttcctatt ctctatgatg ggaaatatgg gaggaggcaa tggccgtaat ccaatgagtt
    18901 ttggacgtag taaggctaaa gcagcaaata aagaagatat taaagtaaga ttttcagatg
    18961 ttgctggagc tgaggaagaa aaacaagaac tagttgaagt tgttgagttc ttaaaagatc
    19021 caaaacgatt cacaaaactt ggagcccgta ttccagcagg tgttcttttg gagggacctc
    19081 cggggacagg taaaactttg cttgctaagg cagtcgctgg agaagcaggt gttccattct
    19141 ttagtatctc aggttctgac tttgtagaaa tgtttgtcgg agttggagct agtcgtgttc
    19201 gctctctttt tgaggatgcc aaaaaagcag caccagctat catctttatc gatgaaattg
    19261 atgctgttgg acgtcaacgt ggagtcggtc tcggcggagg taatgacgaa cgtgaacaaa
    19321 ccttgaacca acttttgatt gagatggatg gttttgaggg aaatgaaggg attatcgtca
    19381 tcgctgcgac aaaccgttca gatgtacttg accctgccct tttgcgtcca ggacgttttg
    19441 atagaaaagt attggttggt cgtcctgatg ttaaaggtcg tgaagcaatc ttgaaagttc
    19501 acgctaagaa taagccttta gcagaagatg ttgatttgaa attagtggct caacaaactc
    19561 caggctttgt tggtgctgat ttagagaatg tcttgaatga agcagcttta gttgctgctc
    19621 gtcgcaataa atcgataatt gatgcttcag atattgatga agcagaagat agagttattg
    19681 ctggaccttc taagaaagat aagacagttt cacaaaaaga acgagaattg gttgcttacc
    19741 atgaggcagg acataccatt gttggtctag tcttgtcgaa tgctcgcgtt gtccataagg
    19801 ttacaattgt accacgcggc cgtgcaggcg gatacatgat tgcacttcct aaagaggatc
    19861 aaatgcttct atctaaagaa gatatgaaag agcaattggc tggcttaatg ggtggacgtg
    19921 tagctgaaga aattatcttt aatgtccaaa ccacaggagc ttcaaacgac tttgaacaag
    19981 cgacacaaat ggcacgtgca atggttacag agtacggtat gagtgaaaaa cttggcccag
    20041 tacaatatga aggaaaccat gctatgcttg gtgcacagag tcctcaaaaa tcaatttcag
    20101 aacaaacagc ttatgaaatt gatgaagagg ttcgttcatt attaaatgag gcacgaaata
    20161 aagctgctga aattattcag tcaaatcgtg aaactcacaa gttaattgca gaagcattat
    20221 tgaaatacga aacattggat agtacacaaa ttaaagctct ttacgaaaca ggaaagatgc
    20281 ctgaagcagt agaagaggaa tctcatgcac tatcctatga tgaagtaaag tcaaaaatga
    20341 atgacgaaa
//
LOCUS       DBEJAU010000039        20057 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC323 isolate 683620
            SAMN38261939-rid24807223.denovo.039, whole genome shotgun sequence.
ACCESSION   DBEJAU010000039 DBEJAU010000000
VERSION     DBEJAU010000039.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261939
            Sequence Read Archive: SRR26833919
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 20057)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20057)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576303.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576303.1
            Genome Coverage       :: 154x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/19/2025 01:05:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,121
            CDSs (total)                      :: 2,078
            Genes (coding)                    :: 1,943
            CDSs (with protein)               :: 1,943
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 36
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 72 of 135
            Pseudo Genes (incomplete)         :: 63 of 135
            Pseudo Genes (internal stop)      :: 51 of 135
            Pseudo Genes (multiple problems)  :: 46 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20057
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261939-rid24807223.denovo.039"
                     /strain="GPSC323"
                     /isolate="683620"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            complement(100..450)
                     /gene="rbfA"
                     /locus_tag="ACL29Z_001492"
     CDS             complement(100..450)
                     /gene="rbfA"
                     /locus_tag="ACL29Z_001492"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001273594.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006364 - rRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosome-binding factor RbfA"
                     /protein_id="HGR0069779.1"
                     /translation="MANHFRTDRVGMEIKREVNEILQKKVRDPRVQGVTITDVQMLGD
                     LSVAKVYYTILSNLASDNQKAQIGLEKATGTIKRELGRNLKLYKIPDLTFVKDESIEY
                     GNKIDEMLRNLDKN"
     gene            complement(701..3493)
                     /gene="infB"
                     /locus_tag="ACL29Z_001493"
     CDS             complement(701..3493)
                     /gene="infB"
                     /locus_tag="ACL29Z_001493"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0003743 - translation initiation factor
                     activity [Evidence IEA];
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_process: GO:0006413 - translational initiation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-2"
                     /protein_id="HGR0069780.1"
                     /translation="MSKKRLYEIAKELGKESKEVVARAKELGLDVKSHSSSVEEAVAA
                     KIAASFKPAAAPKVEAKPAAPKVSAEKKTEKSEPAKPAVAKEEAKPAEPVAPKTEKVA
                     AKPQSRNFKAEREARAKEQAERRKQNKGNNRDQQQNGNRQKNDGRNGGKQGQSNRDNR
                     RFNDQAKKQQGQQKRRNERRQQEDKRSNQAAPRIDFKARAAALKAEQNAEYARSSEER
                     FKQYQAAKEALAQANKRKEPEEIFEEAAKLAEQAQQVQAVVEVVPEKKEPAVDTRRKK
                     QARPDKNRDDYDHEEDGPRKQQKNRSSQNQVRNQKNSNWNNNKKNKKGNNKNNRNQTP
                     KPVTERKFHELPTEFEYTDGMTVAEIAKRIKREPAEIVKKLFMMGVMATQNQSLDGET
                     IELLMVDYGIEAKQKVEVDNADIERFFVEDGYLNEDELVERPPVVTIMGHVDHGKTTL
                     LDTLRNSRVATGEAGGITQHIGAYQIVENGKKITFLDTPGHAAFTSMRARGASVTDIT
                     ILVVAADDGVMPQTIEAINHSKAANVPIIVAINKIDKPGANPERVIGELAEHGVMSTA
                     WGGDSEFVEISAKFNQNIEELLETVLLVAEIQELKADPTVRAIGTVIEARLDKGKGAV
                     ATLLVQQGTLNVQDPIVVGNTFGRVRAMTNDLGRRVKVAGPSTPVSITGLNEAPMAGD
                     HFAVYEDEKSARAAGEERAKRALMKQRQATQRVSLENLFDTLKAGELKSVNVIIKADV
                     QGSVEALSASLQKIDVEGVKVTIVHSAVGAINESDVTLAEASNAFIVGFNVRPTPQAR
                     QQAEADDVEIRLHSIIYKVIEEMEEAMKGMLDPEFEEKVIGEAVIRETFKVSKVGTIG
                     GFMVINGKVARDSKVRVIRDGVVIYDGELASLKHYKDDVKEVTNGREGGLMIDGYNDI
                     KMDDVIEAYVMEEIKR"
     gene            complement(3510..3809)
                     /locus_tag="ACL29Z_001494"
     CDS             complement(3510..3809)
                     /locus_tag="ACL29Z_001494"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399195.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlxQ-related RNA-binding protein"
                     /protein_id="HGR0069781.1"
                     /translation="MNKQKISNLLGLAQRAGRIISGEELVVKAIQDGKAKLVFLAHDA
                     GPNLAKKIQDKSHYYQVEIVTVFSTLELSIAVGKSRKVLAVTDAGFTKKMRSLME"
     gene            complement(3802..4095)
                     /locus_tag="ACL29Z_001495"
     CDS             complement(3802..4095)
                     /locus_tag="ACL29Z_001495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000857559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlxR family protein"
                     /protein_id="HGR0069782.1"
                     /translation="MKTRKIPLRKSVVSNEVIDKRDLLRIVKNKEGQVFIDPTGKANG
                     RGAYIKLDNAEALEAKKKKVFNRSFSMEVEESFYDELIAYVDHKVKRRELGLE"
     gene            complement(4117..5253)
                     /gene="nusA"
                     /locus_tag="ACL29Z_001496"
     CDS             complement(4117..5253)
                     /gene="nusA"
                     /locus_tag="ACL29Z_001496"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000032293.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_process: GO:0006353 - DNA-templated transcription
                     termination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination factor NusA"
                     /protein_id="HGR0069783.1"
                     /translation="MSKEMLEAFRILEEDKGIKKEDIIDAVVESLRSAYRRRYGQSDS
                     VAIDFNEKTGDFTVYTVREVVDEVFDSRLEISLKDALAINSAYELGDKIKFEEAPAEF
                     GRVAAQSAKQTIMEKMRKQTRAITYNTYKEHEQEIMSGTVERFDNRFIYVNLGSIEAQ
                     LSKQDQIPGEVFASHDRIEVYVYKVEDNPRGVNVFVSRSHPEMIKRLMEQEIPEVYDG
                     TVEIMSVAREAGDRTKVAVRSHNPNVDAIGTIVGRGGANIKKITSKFHPARYDAKNDR
                     MVPIEENIDVIEWVADPAEFIYNAIAPAEVDQVIFDENDSKRALVVVPDNKLSLAIGR
                     RGQNVRLAAHLTGYRIDIKSASEFEAMEDAASVELEVENDTVEE"
     gene            complement(5297..5776)
                     /gene="rimP"
                     /locus_tag="ACL29Z_001497"
     CDS             complement(5297..5776)
                     /gene="rimP"
                     /locus_tag="ACL29Z_001497"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000338698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0042274 - ribosomal small subunit
                     biogenesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome maturation factor RimP"
                     /protein_id="HGR0069784.1"
                     /translation="MDAIATIVELVREVVEPVIEAPFELVDIEYGKIGSDMILSIFVD
                     KPEGITLNDTADLTEMISPVLDTIKPDPFPEQYFLEITSPGLERPLKTKDAVAGAVGK
                     YIHVGLYQAIDKQKVFEGTLLAFEEDELTMEYMDKTRKKTVRIPYSLVSKARLAVKL"
     gene            complement(5902..6537)
                     /gene="trmB"
                     /locus_tag="ACL29Z_001498"
     CDS             complement(5902..6537)
                     /gene="trmB"
                     /locus_tag="ACL29Z_001498"
                     /EC_number="2.1.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001266107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008176 - tRNA
                     (guanine(46)-N7)-methyltransferase activity [Evidence
                     IEA];
                     GO_process: GO:0006400 - tRNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (guanosine(46)-N7)-methyltransferase TrmB"
                     /protein_id="HGR0069785.1"
                     /translation="MRVRNRKGATELLEANPQYVVLNPLEAKAKWRDLFGNDNPIHVE
                     VGSGKGAFVSGMAKQNPDINYIGIDIQKSVLSYALDKVLEVGVPNIKLLWVDGSDLTD
                     YFEDDEIDRLYLNFSDPWPKKRHEKRRLTYKTFLDTFKRILPENGEIHFKTDNRGLFE
                     YSLVSFSQYGMKLNGVWLDLHASDFEGNVMTEYEQKFSNKGQVIYRVEAEF"
     gene            complement(6534..7328)
                     /gene="ccrZ"
                     /locus_tag="ACL29Z_001499"
     CDS             complement(6534..7328)
                     /gene="ccrZ"
                     /locus_tag="ACL29Z_001499"
                     /EC_number="2.7.1.15"
                     /EC_number="2.7.1.229"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000363010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004747 - ribokinase activity [Evidence
                     IEA];
                     GO_function: GO:0016773 - phosphotransferase activity,
                     alcohol group as acceptor [Evidence IEA];
                     GO_function: GO:0019200 - carbohydrate kinase activity
                     [Evidence IEA];
                     GO_process: GO:0006270 - DNA replication initiation
                     [Evidence IEA];
                     GO_process: GO:0051726 - regulation of cell cycle
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cell cycle regulator CcrZ"
                     /protein_id="HGR0069786.1"
                     /translation="MDLGDNELTLTPIPGKSGKAYMGSYPDGKRIFVKMNTSPILPGL
                     AREQIAPQLLWSRRLADGRDMCAQEWLTGKILTPYDMNRKQIVNILTRLHRSRPLMTQ
                     LSRLGYAMETPVDLLQSWQETASDALRKNHFISEVMADLRQTIPGFREDHATIVHGDV
                     RHSNWIETDSGLIYLVDWDSVRLTDRMFDVAHMLCHYISEHQWKEWLTYYGYKYNQTV
                     LSKLYWYGQLSYLSQISKYYMNQDLENVNREIHGLRHFRDKYGKRR"
     gene            complement(7489..8100)
                     /locus_tag="ACL29Z_001500"
     CDS             complement(7489..8100)
                     /locus_tag="ACL29Z_001500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000394041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II CAAX endopeptidase family protein"
                     /protein_id="HGR0069787.1"
                     /translation="MEFFDKFHALCFGFLVLIIVITVPYTINHGGFFQNESALILVSL
                     LVTSLSVAYARKFEMISFGMLSKKQLLLFIAIFLLSVLETLVYIHFFAVSSGSGVQHL
                     AEVSRGISLSLILTTSVFGPIQEELIFRGLLQGAVFDNSWLGLVLTSSLFSFMHGPSN
                     VPSFIFYLLGGLLLGFAYKKSQNLWVSTLVHMFYNSWPLLYYL"
     gene            complement(8251..8484)
                     /gene="blpZ"
                     /locus_tag="ACL29Z_001501"
     CDS             complement(8251..8484)
                     /gene="blpZ"
                     /locus_tag="ACL29Z_001501"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000276505.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="immunity protein BlpZ"
                     /protein_id="HGR0069788.1"
                     /translation="MYKHLFFLDSKTLDRLTPYILVLASDTIAFNVFVLTFVSAVVFN
                     FLNSMLALMAIFIGAGYVVGFWLLILNENQRAN"
     gene            complement(8526..9215)
                     /locus_tag="ACL29Z_001502"
     CDS             complement(8526..9215)
                     /locus_tag="ACL29Z_001502"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000760553.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysostaphin resistance A-like protein"
                     /protein_id="HGR0069789.1"
                     /translation="MKKYQLLFKISAVFSYLFFVFGLSQMTLIIQNYWQFSSQIGNFV
                     WIQNFLSLLFSGVMIWILVKTGHGYLFHIPRKKWLWYSILTVLVVVLQISFNVQTAKH
                     VQSTAEGWAVLIGYSGTNFAELGIYITLFFLTPLMEELIYRGLLQHAFFKHSRFGLDL
                     LLPSILFALPHFSSLPSLLDIFIFATSGIIFASLTRYTKSIYPSYAVHVINNIFATLP
                     FLLTFLHRVLG"
     gene            complement(9267..9650)
                     /locus_tag="ACL29Z_001503"
     CDS             complement(9267..9650)
                     /locus_tag="ACL29Z_001503"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="immunity protein"
                     /protein_id="HGR0069790.1"
                     /translation="MKYRLFFVIFLSSVLDILLGTFLQISIVSIGWLVLYSGLFEAGV
                     FLLANKGVAVKIKEVDIRNRFKFIFGKTLWFQILLLIFLIIKLYLGLDARLILFYGHI
                     FIVFNALMYLLSSSQVSLKKNKLSS"
     gene            complement(10279..10598)
                     /locus_tag="ACL29Z_001504"
                     /pseudo
     CDS             complement(10279..10598)
                     /locus_tag="ACL29Z_001504"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001826248.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="immunity protein"
     gene            complement(11118..11237)
                     /locus_tag="ACL29Z_001505"
     CDS             complement(11118..11237)
                     /locus_tag="ACL29Z_001505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000346296.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PncF family bacteriocin immunity protein"
                     /protein_id="HGR0069791.1"
                     /translation="MDFKSFIIGLVVGIFGPYMDDLIRKIFSKSSKKDTDSTL"
     gene            complement(11341..11490)
                     /gene="blpO"
                     /locus_tag="ACL29Z_001506"
     CDS             complement(11341..11490)
                     /gene="blpO"
                     /locus_tag="ACL29Z_001506"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001818346.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-like peptide BlpO"
                     /protein_id="HGR0069792.1"
                     /translation="MNTKMMSQFSVMDNEMLACVEGGDIDWGRKISCAAGVAYGAIDG
                     CATTV"
     gene            complement(11734..11982)
                     /gene="blpK"
                     /locus_tag="ACL29Z_001507"
     CDS             complement(11734..11982)
                     /gene="blpK"
                     /locus_tag="ACL29Z_001507"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000379965.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-like peptide BlpK"
                     /protein_id="HGR0069793.1"
                     /translation="MDTKMMSQFSVMDTEMLACVEGGGCNWGDFAKAGVGGAAVVAAL
                     GCAAGGVKYGKILGPWGAAIGGIGGAVVCGYLAYTATS"
     gene            complement(12051..12320)
                     /gene="blpJ"
                     /locus_tag="ACL29Z_001508"
     CDS             complement(12051..12320)
                     /gene="blpJ"
                     /locus_tag="ACL29Z_001508"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001093248.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-like peptide BlpJ"
                     /protein_id="HGR0069794.1"
                     /translation="MNTKMLSQLEVMDTEMLAKVEGGYSSTDCQNALITGVTTGIITG
                     GTGAGLATLGVAGLAGAFVGAHIGAIGGGLTCLGGMVGDKLGLSW"
     gene            complement(12787..12984)
                     /gene="blpI"
                     /locus_tag="ACL29Z_001509"
     CDS             complement(12787..12984)
                     /gene="blpI"
                     /locus_tag="ACL29Z_001509"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001093259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-like peptide BlpI"
                     /protein_id="HGR0069795.1"
                     /translation="MNTKMMEQFSVMDNEELEIVSGGRGNLGSAIGGCIGAVLLAAAT
                     GPITGGAATLICVGSGIMSSL"
     gene            13266..13853
                     /locus_tag="ACL29Z_001510"
     CDS             13266..13853
                     /locus_tag="ACL29Z_001510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001855030.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008233 - peptidase activity [Evidence
                     IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine peptidase family C39 domain-containing
                     protein"
                     /protein_id="HGR0069796.1"
                     /translation="MTSYKRTFVPQIDARDCSVAALASIAKFYGSDFSLAHLRELAKT
                     NKEGTTALGIVKAADEMGFETRPVQADKTLFDMSDVPYPFIVHVNKEGKLQHYYVVYQ
                     TKKDYLIIGDPDPSVKITKMSKERFFYEWTGVAIFLAPKPSYQPHKDKKNGLLSKLPS
                     SDFQTKISHCLHCSLKLISHYYQYRWFLLSPRNLG"
     gene            13780..15423
                     /locus_tag="ACL29Z_001511"
     CDS             13780..15423
                     /locus_tag="ACL29Z_001511"
                     /inference="COORDINATES: protein motif:HMM:TIGR01193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_component: GO:0043190 - ATP-binding cassette (ABC)
                     transporter complex [Evidence IEA];
                     GO_function: GO:0008234 - cysteine-type peptidase activity
                     [Evidence IEA];
                     GO_function: GO:0043214 - ABC-type bacteriocin transporter
                     activity [Evidence IEA];
                     GO_process: GO:0043213 - bacteriocin transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptide cleavage/export ABC transporter"
                     /protein_id="HGR0069797.1"
                     /translation="MVLSSLLVTIINIGGSYYLQGILDEYIPNQMKSTLGIISVGLVI
                     TYILQQVMSFSRDYLLTVLSQRLSIDVILSYIRHIFELPMSFFATRRTGEIISRFTDA
                     NSIIDALASTILSLFLDVSILILVGGVLLAQNPNLFLLSLLSIPIYMFIIFSFMKPFE
                     KMNHDVMQSNSMVSSAIIEDINGIETIKSLTSEENRYQNIDSEFVDYLEKSFKLSKYS
                     ILQTSLKQGTKLVLNILILWFGAQLVMSSKISIGQLITFNTLFSYFTTPMENIINLQT
                     KLQSAKVANNRLNEVYLVESEFQVQENPVHSHFLMGDIEFDDLSYKYGFGRDTLTDIN
                     LTIKQGDKVSLVGVSGSGKTTLAKMIVNFFEPYKGHISINHQDIKNIDKKVLRRHINY
                     LPQQAYIFNGSILENLTLGGNHMISQEDILRACELAEIRQDIERMPMGYQTQLSDGAG
                     LSGGQKQRIALARALLTKAPVLILDEATSGLDVLTEKKVIDNLMSLTDKTILFVAHRL
                     SIAERTNRVIVLDQGKIIEVGSHQELMQAQGFYHHLFNK"
     gene            15434..16795
                     /locus_tag="ACL29Z_001512"
     CDS             15434..16795
                     /locus_tag="ACL29Z_001512"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001069090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin secretion accessory protein"
                     /protein_id="HGR0069798.1"
                     /translation="MNPNLFRSVEFYQRRYHNYATVLIIPLSLLFTFILIFSLVATKE
                     ITVTSQGEITPTSVIASIQSTSDNPILANHLVANQVVEKGDLLIKYSETMEESQKTAL
                     ETQLQRLEKQKEGLGILKQSLEKATDLFSSEDEFGYHNTFMNFTKQSHDIELGISKTN
                     TEVSNQANLTNSSSSAIEQEITKVQQQIGEYQELRDAIVNKRARLPTGNPHQSILNRY
                     LIASQEQTQGTAEEPFLSQINQSIAGLESSIASLKIQQAGIGSVATYDNSLATKIEVL
                     RTQFLQTASQQQLTVENQLTELKVQLDQATQRLENNTLTAPSKGIVHLNSEFEGKNRI
                     PTGTEIAQIFPVITDTREVLITYYVSSDYLPLLDKGQTVRLKLEKIGNHDTTIIGQLQ
                     TIDQTPTRTEQGNLFKLTALAKLSNEDSKLIQYGLQGRVTSVTTKKTYFDYFKDKILT
                     HSD"
     gene            16852..17007
                     /gene="blpC"
                     /locus_tag="ACL29Z_001513"
     CDS             16852..17007
                     /gene="blpC"
                     /locus_tag="ACL29Z_001513"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000358812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="quorum-sensing system pheromone BlpC"
                     /protein_id="HGR0069799.1"
                     /translation="MDKKQNLTSFQELTTTELNQIIGGGWWEDFLYRFNIIEQKNTKG
                     FHQPIQL"
     gene            complement(17051..18391)
                     /locus_tag="ACL29Z_001514"
     CDS             complement(17051..18391)
                     /locus_tag="ACL29Z_001514"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001099894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GHKL domain-containing protein"
                     /protein_id="HGR0069800.1"
                     /translation="MNVAWILLYTLVTHGLKIVIFFKVDGISLTFERIFKAFLFKILL
                     AVVFGMLGYMVGNVYLSYFMEPLYGIGLSFLLLRELPKKLLLFYGLFPMILVNLFYRG
                     VSYFVLPFLGQGQVYDDYSFIWLCIIIFNFFISLAFLKWLDYDFTSLRKGILDKDFQK
                     SLTQINWIMGAYYLVIQNLSYFEYEQGIQSTTVRHLILVFYLLFFMGIIKKLDTYLKD
                     KLHERLNQEQDLRYREMERYSRHIEELYKEVRSFRHDYTNLLTSLRLGIEEEDMEQIK
                     EIYDSVLKDSSEKLQDNKYDLGRLVNVRDRALKSLLAGKFIKARDKNIVFNVEVPEEI
                     QVEGMSLLDFLTVVSILCDNAIEASVEACQPHVSIAFFKNGAQETFIIENSIKEEGID
                     ISEIFSFGASSKGEERGVGLYTVMKIVESHPNTSLNTTCQDHVFRQVLTVIHIE"
     gene            complement(18405..19142)
                     /locus_tag="ACL29Z_001515"
     CDS             complement(18405..19142)
                     /locus_tag="ACL29Z_001515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001219153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HGR0069801.1"
                     /translation="MRIFVLEDDFSQQTRIETTIEKLLKEYHITLSSFEVFGKPDQLL
                     AEVHEKGAHQLFFLDIEIRNEEMKGLEVARKIRNRDPYALIVFVTTHSEFMPLSFRYQ
                     VSALDYIDKALSAEEFESRIETALLYANGQDSKSLAEDCFYFKSKFAQFQYPFKEVYY
                     LETSTRPHRVILYTKTDRLEFTASLEEVLKQEPRLLQCHRSFLINPANVVHLDKKEKL
                     LFFPNGGSCLIARYKVREVSEAINNLH"
     gene            complement(19147..19485)
                     /locus_tag="ACL29Z_001516"
     CDS             complement(19147..19485)
                     /locus_tag="ACL29Z_001516"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000682119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LytTR family DNA-binding domain-containing
                     protein"
                     /protein_id="HGR0069802.1"
                     /translation="MKYMIIQTQKTVYKVNIDDIYYIQTHPTKAHTVKIVTEEASFNM
                     VQNLSNLENQYGETLMRCHRNCLVNLDKVKSIDFQERILFLGEEGQYAVKYARRRYRE
                     IRQKWLKEGE"
     gene            19761..>20057
                     /locus_tag="ACL29Z_001517"
     CDS             19761..>20057
                     /locus_tag="ACL29Z_001517"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864062.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helicase BlpT"
                     /protein_id="HGR0069803.1"
                     /translation="MTDTDPIKRAHTLITDLNKAYQACKQASADDVRFQEQLNSILGF
                     LAKAETVDNRFLIELEKFYQTSSLLMGLSALDPDAPTRAAWRAYDRFHFDQVKTK"
BASE COUNT         6248 a         4352 c         3349 g         6108 t
ORIGIN      
        1 ggcgtactat tctagtttca atatatttta aaagaatatt tttccatttc aaattcaacc
       61 tattttcctc caccaaaaaa gaggggcaac ccctcttctt tagttcttat ccagattgcg
      121 tagcatctcg tcaatcttgt ttccatactc gatggactcg tctttgacga aggtcaaatc
      181 tgggattttg tacaatttca aattgcgacc aagttcacgt ttgatggtac cagttgcttt
      241 ttcaagcccg atttgggctt tttggttatc cgaagcaagg ttactcaaaa tggtgtaata
      301 aaccttggca acagacaagt cacccagcat ctgaacatct gtgatggtca caccttggac
      361 acgtggatca cggactttct tttgcaaaat ctcattgact tcacgcttga tttccatgcc
      421 cacacgatct gtacggaaat gatttgccat gatattcctt tctctacttt gaaccaaaag
      481 ctaggccagc agacctagct attttaaact tcttgatttt cagtttaaat tgaaacgaag
      541 ttcaatttga agtcatctgc ttctttcgcc gtggtgaaag tgatggaact gatttatcag
      601 tcccatcaca ggggattttt gagaccctag gctcaaaaat aagcaatgaa accatcggtt
      661 tacttgcgtc cctcaccacc taagaaagga gcaaaaaatc ttatctcttg atttcttcca
      721 tgacatacgc ctcaatcaca tcatccatct taatatcatt gtagccgtcg atcatcaatc
      781 caccttcacg gccgtttgta acttccttaa cgtcgtcttt atagtgtttc aagcttgcga
      841 gttcaccatc atagataacg acaccatcac ggataacacg gactttagag tcacgggcaa
      901 ccttaccgtt gataaccata aatccaccga tagttcccac tttagacacc ttgaaggttt
      961 cacggataac cgcttcacca ataacttttt cttcaaattc tggatcaagc atccctttca
     1021 tagcttcttc catctcttcg ataaccttgt agataatgct gtgaagacgg atttctacat
     1081 cgtcagcttc tgcttgttga cgagcttgtg gtgtagggcg tacgttgaaa ccaacgataa
     1141 aggcatttga agcttcggca agggtcacgt ctgattcgtt gatagcaccg accgctgagt
     1201 ggacgatagt cactttgaca ccttccacgt caatcttttg aagtgaggca gaaagggctt
     1261 caacagaacc ttgtacatca gccttgatga taacattaac agatttgagt tccccagctt
     1321 taagggtatc aaagaggttt tcaaggctaa cacgttgggt agcttgacgt tgtttcatga
     1381 gggcacgttt ggcacgctct tcacctgctg cacgcgcaga tttttcatcc tcgtaaacgg
     1441 caaagtggtc acccgccatc ggtgcttcgt tcaaacctgt gatagagact ggtgttgatg
     1501 gtccagcaac tttaacacga cgaccaaggt cgttggtcat agcacggaca cgaccgaagg
     1561 tatttccgac aacgattggg tcttgaacat tcaaggtacc ttgttgtaca agaagggttg
     1621 cgaccgcacc ttttccttta tccaagcgcg cttcgataac cgtaccgatt gcacgcactg
     1681 ttgggtctgc cttgagttct tggatttcag ctacaagaag gactgtttcc aacaattctt
     1741 cgatattttg gttgaattta gctgagattt caacaaattc agaatctcca ccccaagcgg
     1801 ttgacatcac accatgctct gccaattcac cgataacgcg ttctgggtta gcacctggtt
     1861 tatcaatctt gttaatggct acgatgattg gaacgttggc cgcttttgag tggttaatgg
     1921 cttcgatagt ctgaggcata accccgtcat ctgccgctac gaccaagatc gtaatatcgg
     1981 taacagaagc accacgcgca cgcattgatg taaaggccgc gtgtcctggt gtatcaagga
     2041 aggtaatctt cttaccattt tccacgattt ggtaggcacc gatatgctga gtaataccac
     2101 ctgcttcacc tgtcgcaaca cgtgagttac gaagagtatc caaaagggtt gttttaccgt
     2161 ggtcaacgtg tcccatgata gtaacaactg gtggacgctc aaccaattca tcttcattga
     2221 gataaccatc ttcgacaaag aaacgttcga tgtcagcatt atccacttca accttttgtt
     2281 tggcttcgat accgtaatcc accatgagga gttcaattgt ttccccatcc aaggattggt
     2341 tttgtgtggc catgacaccc atcatgaaaa gtttcttaac aatttcagct ggttcacgtt
     2401 tgatacgttt tgcgatttcc gcaacggtca taccatctgt atattcaaat tctgttggca
     2461 attcatggaa tttacgctcc gtaacaggtt ttggagtctg attacggttg ttcttgttat
     2521 tgcctttttt gttctttttg ttgttattcc agttactatt cttttgattt ctcacttgat
     2581 tttgactact tcgattcttt tgttgttttc taggaccatc ttcttcatga tcataatcgt
     2641 cacgattttt gtctggtcga gcttgttttt tacgacgtgt atccactgca ggttcttttt
     2701 tctcaggaac gacttcaacc actgcttgaa cttgctgtgc ttgttcagct aacttagccg
     2761 cttcttcaaa gatttcctct ggttccttgc gtttgttagc ttgagccaag gcttctttag
     2821 cagcctgata ctgcttgaag cgttcctcac ttgaacgagc gtactctgca ttttgctctg
     2881 cttttagggc tgctgcacgg gctttaaagt caatacgtgg agccgcttga tttgaacgtt
     2941 tatcctcttg ctgacggcgc tcatttctac gtttttgctg accttgctgc ttcttagctt
     3001 ggtcattaaa gcgacgattg tcgcggttgc tttgaccttg ttttccacca ttacggccgt
     3061 cgtttttctg acggtttccg ttttgttgtt ggtcacggtt attgccctta ttttgcttgc
     3121 gtcgttctgc ctgctcttta gcacgggctt cacgctcagc cttgaaatta cgactttgcg
     3181 gtttcgctgc tactttttct gttttcggag caactggctc agccggtttt gcctcttcct
     3241 tagctacagc tggtttagct ggctcagatt tttcggtttt cttttctgca cttacttttg
     3301 gtgctgcagg ttttgcttct actttcggag cagctgcagg cttaaagctg gcagcaattt
     3361 ttgcagcgac agcttcttcc acacttgatg agtggctttt cacatccaag cccaactctt
     3421 ttgcacgcgc tacaacttct ttactttctt ttccaagttc ttttgcgatt tcgtacaatc
     3481 ttttcttaga caaatcatgt cctcctcttc tattccataa gagacctcat tttctttgta
     3541 aatccagcat ctgttacagc caaaaccttt ctcgatttcc cgactgctat gcttaattcc
     3601 agtgttgaaa acacggttac aatttctact tgataataat gacttttatc ttgaatcttc
     3661 ttggccagat tgggtccagc atcatgagct agaaagacca acttggcctt gccgtcttga
     3721 atggccttga ccaccaattc ttcacccgat atgatgcgcc ctgctcgctg agcaagcccc
     3781 aagagattac ttatcttttg cttattcaag tcccaactct cttcttttca ctttgtgatc
     3841 cacataagcg atcaactcgt cataaaagct ttcttccact tccatgctaa agctgcggtt
     3901 aaagaccttc ttctttttcg cctctagggc ttctgcattg tctagtttga tataagcgcc
     3961 gcggccattg gccttgcccg taggatcaat aaagacttgt ccttccttgt tcttgacaat
     4021 gcggagcaaa tcacgcttat caatcacttc gttagacaca acagacttgc gcaaagggat
     4081 ttttcttgtt ttcatctttc cctcctctag cagcttttat tcttctacag tatcgttttc
     4141 tacttccaac tctactgaag cagcgtcttc catggcttca aattcgctag cagacttgat
     4201 atcgatacgg taaccagtca agtgagccgc caagcgcacg ttttgtccac gacgaccaat
     4261 ggcaagagaa agcttgttat ctggaacaac caccaaggca cgtttgctgt cgttttcatc
     4321 aaagataact tggtcaacct cagcaggagc gatggcattg tagataaatt cagctggatc
     4381 tgctacccac tcgataacat cgatattttc ttcgattggt accatgcggt catttttagc
     4441 atcgtaacga gctgggtgga atttgctagt aatcttcttg atattagcac caccacgtcc
     4501 aactattgta ccgatagcat ccacgtttgg attgtggcta cgaacagcaa ccttcgtacg
     4561 gtcacctgct tcacgagcca cgctcatgat ttcaacagtt ccatcataaa cttctggaat
     4621 ttcttgctcc attaaacgtt tgatcatttc tggatgacta cggctaacaa agacgttcac
     4681 accacgaggg ttgtcttcaa ccttgtaaac ataaacttcg atacgatcat gagaagcaaa
     4741 aacttctcca ggaatttggt cttgttttga caattgggct tcgatgctac caaggttgac
     4801 atagataaag cggttgtcaa agcgttctac tgtaccagac atgatttctt gctcatgttc
     4861 tttgtaagta ttgtaagtga tggcacgtgt ttgcttgcgc attttttcca tgatggtttg
     4921 tttggcagac tgggctgcta cacgaccaaa ctcagctggt gcttcttcaa acttgatttt
     4981 gtctccaagt tcataagctg aattaatggc aagagcatct ttcaagctga tttccaaacg
     5041 gctatcaaat acttcatcaa caacttcacg gacagtataa actgtaaagt cacctgtttt
     5101 ttcgttgaag tcaatagcta cgctgtctga ctgaccatag cgtctgcgat aagcggaacg
     5161 aagcgactct actactgcgt cgatgatatc ttcttttttg attcccttgt cttcttccaa
     5221 aatgcggaag gcctctagca tttctttact catgttttct tcacttttga atcctcaaaa
     5281 gctatccttt ctttttctat aatttaactg ctaaacgtgc ttttgatact aaactgtatg
     5341 gaattcggac ggttttctta cgcgtcttgt ccatatattc catagtcaac tcgtcctctt
     5401 cgaaggccaa caaggttcct tcaaagacct tttgcttatc gatggcttgg tagagtccga
     5461 catggatgta ttttccaacc gctccagcga cggcatcctt ggttttcaaa ggacgttcca
     5521 agcctggact ggtaatttct aggaaatatt gttctgggaa gggatctggc ttgatggtgt
     5581 ctaggacagg actgatcatt tctgtcaagt ctgccgtgtc gttcaaggta attccttcgg
     5641 gtttatctac aaaaatactg agaatcatgt cactgccaat ctttccatac tcgatatcca
     5701 cgagttcaaa aggagcttct atgacaggtt ctacaacttc tctgactaat tctacgattg
     5761 ttgcgattgc gtccacctcc tcataagcaa gaggcgaaga tatttccccg cctcactttt
     5821 catattctta ttatcagtat agcacgtttg ccaacttatg taaagcaaaa gcacttgtac
     5881 agcctaattt taggctatct cttaaaattc tgcctcaact cggtagataa cttgcccctt
     5941 gtttgagaat ttttgctcgt attctgtcat gacattgcct tcaaaatcac tggcatgcaa
     6001 atctagccag acaccattga gtttcatgcc atattgagaa aagctcacta aactgtactc
     6061 aaacaagcca cggttatccg tcttgaaatg aatttctcca ttttcaggca agatacgttt
     6121 gaaggtgtcc aaaaaggtct tgtaggtcaa acgacgcttt tcatggcgtt ttttcggcca
     6181 tggatctgaa aagttcagat acaagcgatc aatctcatcg tcttcaaagt agtcagtcaa
     6241 gtcagaacca tctacccaca agagtttaat gttaggcact ccaacttcaa gcaccttgtc
     6301 caaagcgtag ctcaaaacag acttttgaat atcaatcccg atatagttga tgtcagggtt
     6361 ttgcttggcc atacctgaaa caaaggcacc ctttccactt ccaacttcca catgaatggg
     6421 attatcattg ccaaacaagt cccgccattt tgccttggct tccaagggat tgaggaccac
     6481 atactgggga tttgcctcta gtaattctgt tgccccttta cgatttctaa ctctcatctt
     6541 ctctttccat acttgtctcg gaaatgacgc aaaccatgaa tctcccgatt gacattttct
     6601 aaatcttggt tcatataata cttggaaatc tgactcaaat aagacaattg accataccaa
     6661 tacaatttac ttaataccgt ttgattgtac ttgtaaccgt agtaggtcaa ccattccttc
     6721 cactgatgtt ctgaaatata atggcagagc atatgggcca catcaaacat gcgatcggtc
     6781 aagcgaaccg aatcccaatc tactaaataa atcaagccac tatctgtctc aatccaatta
     6841 ctatgtcgta catctccatg gacaatggtc gcatggtcct ctctaaatcc tggaatagtc
     6901 tgacgtaaat cagccatcac ttcactgata aaatgatttt tacgcaaagc atctgaagcc
     6961 gtttcttgcc aagactgtag taaatctaca ggtgtttcca tggcatagcc caaacgactc
     7021 aattgtgtca tcaacggacg tgagcgatga agacgggtta aaatattgac gatttgctta
     7081 cgattcatat catagggggt caatatcttg cctgtcaacc attcttgagc acacatatca
     7141 cgcccatctg ccaaacgacg actccataat aattgtggag caatttgttc tctagctaga
     7201 ccaggtagga ttggagaggt gttcattttt acaaagatgc gcttcccgtc aggatagcta
     7261 cccatataag ccttgccact tttcccaggt atgggagtca gtgttagctc attatcaccc
     7321 aaatccattt ctttcctccg tataaagttt ccttactatt ctactagttt ttggcctatt
     7381 cgtcaaccac tctaacccga ttctcaaaga aaagcctctg gattggcttg ggtatcatta
     7441 tagcttgaaa aaggtaagca ccatcttctg cttacctttt cataattttt ataaataata
     7501 taggagtggc caactgttgt aaaacatgtg gactagagta gaaacccata ggttttgact
     7561 ctttttataa gcaaagccca gcaacaaacc cccaagtaga taaaaaataa acgaagggac
     7621 attagaaggt ccatgcatga aagaaaagag agaggaagtt agcacaagcc ctaaccaaga
     7681 attgtcaaaa accgcacctt gaagaagtcc tctgaaaatg agttcctcct ggatggggcc
     7741 aaaaactgag gtagtcaaaa tcaaagacag ggaaattcct ctgctgactt ccgccaagtg
     7801 ttggacccct gagccagaag aaacagcgaa gaaatgaata taaaccagcg tctcaagtac
     7861 acttagaaga aagattgcaa tgaaaagcaa aagttgtttc ttgcttaaca tcccaaaaga
     7921 aatcatttca aactttctag cataagcaac actcagcgag gttacaagaa gacttacaag
     7981 aatcaatgca gattcatttt gaaaaaaacc cccatggtta atcgtataag gaactgtaat
     8041 gacaattatt agtactaaaa atccaaaaca caaggcatga aatttatcaa aaaactccat
     8101 aaaactatcc tcctcaccaa acagacttcc tacgcgtcat tctttagttc tagcctttcc
     8161 aaaacaaacc attttatact cttcgaaaat caaattcaaa ccacgtcaac gtcgccttgc
     8221 cgtactcaag tacagcctgc ggctagtttc ctagtttgct ctttgatttt cattgagtat
     8281 tagtaaccaa aatccgacca catagccagc ccctatgaat atagccatta aagctagcat
     8341 ggaatttagg aaattaaaaa ccaccgcaga tacaaaggtt agcacaaaaa cattaaaagc
     8401 aatggtgtca gaagccaaga ctagaatata gggtgtcaac cgatctaaag ttttggaatc
     8461 taggaaaaat aagtgtttat acatgataat ctcctctatg gctgaaaagc aagccttttg
     8521 tttttttacc ccaagaccct atgtaaaaaa gtcagcaaaa atggtaatgt tgcgaaaata
     8581 ttattgatca catgcaccgc ataggaagga taaatgctct tggtatagcg ggtcaaacta
     8641 gcaaagatga tgccagatgt tgcaaagatg aagatatcta acaaactagg caggcttgaa
     8701 aaatgaggaa gagcaaataa aattgacgga agaagcaaat caaggccaaa tctcgaatgc
     8761 ttaaaaaagg cgtgttgcag taatcctcta tagattagct cttccataag tggagtcaga
     8821 aagaacaaag ttatatagat acctagctca gcaaagttgg tcccactata accgatcaat
     8881 acagcccaac cttcagcagt tgactgaaca tgtttagctg tctgaacgtt aaaagagatc
     8941 tggagcacta ccactaatac tgtcaaaatc gaataccaaa gccatttttt tcttggaatg
     9001 tgaaagagat aaccatgacc tgtcttaacc agaatccaaa tcatgactcc gctaaatagc
     9061 aaactcaaga aattttgaat ccagacgaaa ttgccaatct gggaagaaaa ttgccaataa
     9121 ttttgaataa taagcgtcat ctgagaaaga ccaaatacga aaaataagta agagaaaact
     9181 gcacttattt tgaatagaag ttgatacttt ttcatagaaa tcctccctac tatgacctca
     9241 ccttgtcagg ctctactgct gtaagattaa gaagacagtt tgtttttttt aaggctaacc
     9301 tgactactag ataatagata cattaaggca ttaaagacaa tgaaaatatg tccatagaat
     9361 aaaatcaacc tcgcatccaa accaagataa agtttgatta tcaaaaagat gagcaaaaga
     9421 atttgaaacc ataaggtttt tccaaaaata aatttaaagc gatttcgaat atctacttcc
     9481 ttgattttta ccgccacccc tttattagca agaaggaaaa ctcctgcttc aaacaaacca
     9541 ctgtaaagaa caagccaccc aatagatacg atagagattt gtaaaaatgt ccctaaaaga
     9601 atatccaaca cactactcaa gaaaataaca aaaaataatc tgtatttcat attaaatacc
     9661 tccattcatt tatttcacta acaatttaat agagccttct actcaaatat cctgtcagaa
     9721 aaggatagaa agctactttt tataatactt caagccccac atgagcagaa gcgtgataaa
     9781 caagcagaga atacacctat ataagcgatt agttgttgat agaattctgt ttctgaaata
     9841 cctctataca aacaaatgac aaacataaaa tctgccaagc cgataaacat aagttgattg
     9901 gttctaggac taaccaaatc atcatttact tatatttaag agtatctctt ttatgttaat
     9961 gtatgttagc actgaaaagc aagacaggcc aataatattt aaaatgaaca gtaacggggt
    10021 taagtctcta aaaaaattat ctactgacac tacaagaaat actatacata ttatagtcga
    10081 aactatcttt ttcttatcca taattattta ctcctttcct aacaaatcca acttatcaat
    10141 caagagcgat ttttaacata atgtagcagc acccgttgca actttgacaa gtttagtata
    10201 tcattgtttt ttaaaatttt tcatccaaat cttgaattgt catcgaaacc tcctaaattg
    10261 caaaaacttc attagcccct actttttata atacttcaaa ccccaaatga gtagaagcat
    10321 gatgatcaag caaagaatag caccaatata agcgattagt tgttgataag attctcctgc
    10381 tgtgatacct ctatacaaac aaataataga cataaagcct gtcaagccga taaacatgag
    10441 ttgattggtt ctaggactaa ccaaatcatc atcttcaaac tctcttaatc tcatttccct
    10501 agtaagataa acagtaacca aaatagaagt caagttaata actactaaaa gaaattggaa
    10561 aactgacgaa atagaaatag ataagtagaa acaagcaaag gcaactgacc caggaacaat
    10621 ctcacaaaga atatgattct ttttaatcaa gaaaatcttt catttctttt ctttcttttt
    10681 aattaaagaa aaatagatca taaccgcaat catataggct atggtataaa atagattata
    10741 ccaaatactc tccctaagcg gataaagaaa gatggacatg atcagataca gaacgaaaat
    10801 aatcagtatt tttttcttca taagttttcc tcctaaatgt gcgatttatc ttagttgagc
    10861 aagaacattt acactgctag tatagcactt attttgacct tggatcactc aaatcataaa
    10921 tggtcatcaa aacctcttga attgtaaaaa ttaaaaaagc aagcatgaaa aacatacttt
    10981 cctctttata ttgtattgat accaacttgt ttgtagactt ttcatcctgc tatcacatat
    11041 cattttgaca ggcgaaacaa tattaaagaa actcccctgt aaattaagct agcaaataca
    11101 ggggagaaat ttatttttta gagagtacta tccgtatcct ttttggaaga ttttgaaaat
    11161 atttttctaa ttaagtcatc catataagga ccaaatatac caactactaa accaataata
    11221 aaacttttaa aatccataat taccaccaac atgttgctgc ataggctaca cctccaagta
    11281 tagctccacc tgcagcacca gttacaccta ttcctatagc aaatggtccc aatagaaatg
    11341 tcaaaccgtt gttgcacacc catcaattgc gccatatgca acccctgctg cacaactaat
    11401 ttttcttccc caatcaatat ctccaccttc aacgcaagca agcatttcat tatccataac
    11461 agaaaattgt gacatcattt ttgtattcat atagtatgtc acttttcagt tacggaacaa
    11521 gtttaatata aaaattatca aaaaaacata ggcaataaag agaaaaatta atttatcata
    11581 gattagaaat aatatgacaa aacaattcaa tgatgttaat tcaatagtct tttgtttttt
    11641 atcagagata cttatggata gataaataag ataggtttga aaagcgaaga gaataataaa
    11701 gaatatagcc ttcataaaat ttagctttca tttttatgat gtagcggtat aggctaaata
    11761 tccacaaacc actgctcctc caattcctcc tattgcagcg ccccatggtc ctagaatttt
    11821 cccatatttc actccacccg ctgcacaacc taaagcagca actacagctg ctcctccaac
    11881 acctgctttg gcaaaatctc cccaattgca tccgccacct tcaacgcaag caagcatttc
    11941 agtatccata acagaaaatt gtgacatcat ttttgtatcc atgacaaata ctcctttttt
    12001 aaaaaactaa aataaatcag aatagaatcc tcataatttt actataagtc ttaccaactt
    12061 agtcccaatt tatcaccaac catacctcct aagcatgtta atccaccccc aattgcacca
    12121 atgtgtgctc caacaaatgc accagcaagt ccagctactc ctaaagtggc caaacctgct
    12181 ccagttccac cagttataat tcccgtagtg actcctgtaa tcagtgcatt ttgacaatca
    12241 gtggagctat accccccttc aactttcgca agcatttcag tatccataac ctctaactgt
    12301 gacaacattt ttgtattcat gatgaatacc tcctttttat tttcaatttg ttaccaaagt
    12361 cttaaattca ataaacaaat agattttttt tagtatcttt ttgattttct taaaaaagta
    12421 tatacgtcta ctatcttctt aaaggtagca gtacctattt tttagtctaa gatttcaata
    12481 atcttgagta tctaaaatat cttaatttcg ttattctcct tgcaataaaa agttttacta
    12541 tactatttat taacttgcag aaagcaaaaa atattagtaa ataatagttt atagttaagt
    12601 tttttattcc taccaatcca tcaactaagt aaagcatcaa cgattacata aacgattgat
    12661 aatataatta aaattttgct aactatctta ttctcatgat tcttagataa ctttgatatt
    12721 ttgtaagtaa gtaaataaga cagtaaatta atagcgataa taatactata tttaagaatc
    12781 ataatcttac aaagaggaca taattcctga acctacacaa ataagtgttg ctgctccccc
    12841 agttatcgga ccagtcgcag cagctaatag tactgctcca atacaaccac cgattgcaga
    12901 tcctaaattg cctcttcctc cactaactat ttcgagttct tcattatcca taacagaaaa
    12961 ttgttccatc atttttgtat tcatgacaaa tactcctttt ttcttttttt atttttgtct
    13021 tgttgtaact ttgataagtt tagtatatca tcgtttttta aaatttttca tccagatctt
    13081 gaattgtcat cgaaacgtct tgaattagct tttttatttc aagccacctc taaatgttta
    13141 aaaaaaataa tttctaatca cttttttacc attcaggaag ttttaatgac tattcaagat
    13201 ttcataaaat atgaacttag ttttatgaca taatagacct atccactata tgaaaagaat
    13261 tgccaatgac ttcttataaa cgtacatttg ttcctcaaat agatgcgaga gactgtagtg
    13321 tcgctgcctt agcctcgatt gctaaattct atggttcaga tttttctcta gctcacttga
    13381 gagaacttgc aaagaccaat aaagaaggga cgactgctct tggcattgta aaagccgctg
    13441 atgaaatggg ctttgaaaca agacctgttc aagcagataa aacgctcttt gacatgagtg
    13501 atgtccccta tccatttatc gttcacgtta acaaagaagg aaaactccaa cattactatg
    13561 ttgtctatca aacaaagaaa gactatctga ttattggtga tcctgaccct tctgtaaaaa
    13621 tcactaaaat gtcaaaagaa cgctttttct atgaatggac tggagtagct atttttctag
    13681 ctcccaaacc cagctatcaa ccccataaag ataaaaagaa tggtctacta agcaagcttc
    13741 cttcctctga ttttcaaaca aaaatctctc attgcttaca ttgttctctc aagcttatta
    13801 gtcactatta tcaatatagg tggttcttac tatctccaag gaatcttgga tgaatacatt
    13861 ccaaatcaga tgaaatcaac tttaggaatc atctcagttg gtctggttat cacctatatc
    13921 ctccaacaag tcatgagctt ctccagagat tatctcctaa ccgttctgag ccagagatta
    13981 agcattgatg tgattttatc ctatattcgc catatttttg aacttcccat gtctttcttt
    14041 gcgacacgtc gtacaggaga aatcatttca cggttcacag atgctaactc tattatagat
    14101 gccttggctt ctaccattct ttctcttttt ctggatgttt ctattctgat tcttgtaggg
    14161 ggcgtcttac tggcacaaaa ccctaatctc ttcctccttt ctcttctttc cattcctata
    14221 tacatgttca tcatcttttc ttttatgaaa ccttttgaaa aaatgaacca tgatgtcatg
    14281 caaagtaatt ctatggttag ctctgccatt atcgaagata tcaacgggat tgaaactata
    14341 aagtcgctca cgagtgaaga aaatcgctat caaaatatag acagcgaatt tgtagattat
    14401 ttggaaaaat cctttaagct cagtaaatat tctattttac aaacgagttt aaagcaggga
    14461 acaaaattag ttctgaatat ccttatccta tggtttggcg ctcaattagt catgtcgagt
    14521 aaaatttcta tcggtcagct gattaccttt aacacacttt tttcttactt tacaactcct
    14581 atggaaaata ttatcaacct ccaaaccaaa ctccaatctg cgaaggtcgc taataaccgt
    14641 ttgaacgaag tctatctagt cgaatctgaa tttcaagttc aagaaaaccc tgtccattca
    14701 cattttttga tgggcgatat tgaatttgat gacctttctt ataagtatgg ttttggacga
    14761 gataccttaa cagatattaa tctcacgatt aaacaaggag ataaggttag cctagttgga
    14821 gttagtggtt ctggtaaaac aactttagcc aaaatgattg tcaatttctt tgaaccctac
    14881 aaagggcata tttccatcaa tcatcaggat attaaaaaca ttgataaaaa agtcttgcgc
    14941 cgtcatatta attacctacc ccaacaagcc tatatcttta atggctctat cttggaaaat
    15001 ttaaccttgg gcggtaatca tatgattagc caagaagata ttctaagagc ttgtgaatta
    15061 gctgaaatcc gtcaagacat tgaaagaatg cctatgggct atcaaactca gctctctgat
    15121 ggagctggtc tatcaggagg acagaagcaa cgaatagccc tcgctcgtgc tcttttaact
    15181 aaagctcctg ttttaatact agacgaagct actagcggtc ttgatgtctt gactgagaaa
    15241 aaagttatag ataatcttat gtccctaact gataaaacca ttctctttgt agcccatcgt
    15301 ctcagtatag ccgaacgaac taaccgtgtc attgttcttg accaggggaa aatcattgaa
    15361 gttggtagtc accaagagtt aatgcaggcg caaggcttct accatcatct gttcaataaa
    15421 taaggagaat gtcatgaatc ctaatctttt tagaagcgtc gagttttatc agagacgtta
    15481 ccataactat gcgacagtat taatcatacc tctttcatta ttatttactt tcatcttgat
    15541 tttctccctt gttgccacaa aagaaattac tgttacttcc caaggggaaa tcacccctac
    15601 aagtgtcatt gcatctattc agtcgaccag tgataatcct atccttgcta atcatttagt
    15661 ggcaaatcaa gtagttgaga aaggtgactt actcatcaaa tactctgaaa caatggaaga
    15721 gagtcagaaa actgccttag aaactcaatt acaaagactt gagaagcaaa aagaaggact
    15781 tggaatcttg aaacaaagct tagaaaaagc gactgatctt ttttctagcg aggatgagtt
    15841 tggctaccat aatactttta tgaattttac taaacaatcc catgatattg aactgggtat
    15901 ctcaaagact aacactgaag tttcaaatca agctaatctt accaatagca gttcatcagc
    15961 catcgaacaa gaaattacaa aagttcaaca acaaattgga gaatatcaag agctgagaga
    16021 tgctatcgta aataaaagag ctcgcttacc aactggcaat ccgcaccagt caattttaaa
    16081 tcgttatctt atagcctctc aagaacaaac acaaggaacg gcagaggagc catttttatc
    16141 tcaaattaat caaagtattg caggtctgga atcatctatc gcaagcctca aaattcagca
    16201 agctggtatc ggaagtgtag caacttatga taatagttta gcaaccaaaa ttgaagtact
    16261 ccgcactcag tttttacaaa cagcctcaca gcaacaacta accgtggaga atcaattaac
    16321 agaattaaaa gtacaactag atcaagcgac acagcgctta gaaaataata ccttaaccgc
    16381 tccaagtaaa ggtatcgttc atctgaacag cgaatttgaa ggtaaaaata gaattccaac
    16441 tggtacagaa attgctcaaa tattccctgt catcacagat acaagagaag tactaatcac
    16501 ttactacgta tcttctgact atctacctct actagataaa ggacaaactg taagattaaa
    16561 actggagaag attggaaatc acgacaccac catcatcggc caacttcaga caattgatca
    16621 aactcctacc agaacagagc aaggaaatct ctttaaatta accgctcttg caaaactatc
    16681 taacgaggat agtaaactca tccaatatgg cttacaaggt cgcgtcacta gtgtaactac
    16741 aaagaaaaca tattttgatt atttcaaaga taaaatttta acccattctg attaattttc
    16801 agataacact ctataactat ttattatctt atcaaaaagg agaatcataa catggataag
    16861 aaacaaaacc taacttcatt tcaagaacta acaactaccg aactcaacca aattataggt
    16921 ggaggatggt gggaagattt cttatataga tttaatataa ttgaacaaaa aaatacaaaa
    16981 ggatttcatc agccaataca actataaaaa aacaagacca agagaacgca ctctcggtct
    17041 tattttttct tcattctata tgtattacag taagtacctg acgaaaaacg tgatcttggc
    17101 aggtggtatt gagactggta ttgggatgac tttccacaat tttcataacg gtatagagac
    17161 caactcctct ctcctcccct ttagaacttg ctccaaagga gaagatttca gaaatatcga
    17221 ttccctcttc tttgatggaa ttttcaatga taaaggtctc ctgtgctcca tttttaaaaa
    17281 aggcaattga aacatgaggt tgacaggctt ctacactagc ttcaatagcg ttgtcacaaa
    17341 ggatagacac aacggttaga aaatcaagta gactcatccc ctctacctga atctcctctg
    17401 gaacttcgac attaaagaca atgttcttat ctctagcttt tataaatttt ccagctagga
    17461 gacttttgag ggcacgatcc cgaacattca ccaatcggcc aaggtcatat ttattgtcct
    17521 gcaatttttc actagaatcc tttaagaccg agtcgtagat ctcttttatc tgctccatat
    17581 cctcctcttc aatgcccaga cgtaagctag tcaagaggtt ggtgtagtca tggcgaaaac
    17641 tccgtacttc cttataaagc tcctctatat gccgactata ccgctccatc tctctgtagc
    17701 gcaagtcctg ctcttggttc agtctctcat ggagtttgtc cttcaaatag gtatccaatt
    17761 tcttgataat ccccataaaa aagagcaggt aaaagactag gatgagatgg cgaacagtcg
    17821 ttgattgaat cccctgttca tattcaaagt aagacagatt ttgtatcacc aaatagtaag
    17881 cccccattat ccagttaatc tgagtcaggg acttttgaaa atctttatcg agaatcccct
    17941 ttctcaagct agtgaaatca tagtccaacc atttcaaaaa agctagagaa atgaagaaat
    18001 tgaaaattat tatacataac caaataaatg agtagtcatc atatacttgc ccttgtccca
    18061 aaaatggaag cacaaaatag gaaacacctc tataaaagag attcactaat atcattggaa
    18121 agagaccata aaagagaagg agttttttag gaagttctct taacaataag aaagataagc
    18181 ctatgccgta caagggttcc ataaaataag ataggtaaac atttcctacc atatagccaa
    18241 gcattccaaa aacaacggcc aacagtatct taaaaagaaa ggccttaaaa atcctctcaa
    18301 aagtgagact aattccatct accttaaaga atatgacaat ttttaatccg tgagtaacaa
    18361 gtgtatacaa caatatccaa gcaacattca taaactctcc tagctcagtg taagttatta
    18421 atagcctcag acacttccct gaccttataa cgcgcgatta gacaacttcc accattggga
    18481 aagaaaagca gtttttcttt cttatctaaa tgcaccacat tggcaggatt gatgagaaaa
    18541 gagcgatggc actgcaagag acgaggctcc tgcttgagaa cctcctctag actcgctgta
    18601 aattccagcc tgtctgtctt ggtatagaga ataacacgat ggggtcttgt ggacgtttcg
    18661 agatagtaaa cctctttaaa aggatactgg aattgagcaa attttgattt aaagtaaaag
    18721 caatcttccg ctagactttt actgtcttga ccattggcat agaggagggc tgtctcgata
    18781 cgagattcaa actcctctgc cgaaagggcc ttatcaatat agtccagagc agacacttgg
    18841 tagcgaaagg acaggggcat aaactccgag tgagtcgtca caaagacaat cagggcatac
    18901 ggatcccgat tccgaatctt tctagccact tccagaccct tcatctcctc atttcgaatc
    18961 tcaatatcca aaaagaatag ctgatgggcc cccttctcat gcacctctgc cagcaattga
    19021 tctggcttac caaaaacttc aaaagaactc agagtgatat gatattcctt caagagtttc
    19081 tcaatcgtcg tttcaattct agtctgttgg gaaaaatcat cttctaaaac aaatattctc
    19141 atcttcttac tctccttctt tcaaccattt ttgacgaatt tctctatagc gacgtctggc
    19201 atacttgaca gcgtattgac cttcttctcc aagaaaaagg attctttctt gaaaatcaat
    19261 cgattttact ttatcaagat tgaccaaaca atttcgatga catctcatca aggtttcccc
    19321 atattggttc tcaagattac ttaaattttg aaccatatta aaactagcct cttctgtaac
    19381 aatctttaca gtatgggctt tagttggatg tgtttggata tagtagatat cgtcgatgtt
    19441 tactttatag actgttttct gcgtctgaat aatcatatat ttcattggat tctcctccta
    19501 agaaaagaat aacagaaaaa atctaacaca agcacaccca atcctaaaca gtctttgaaa
    19561 actcctaaaa ggattatttt ctacaacatc atgatgagct tacaactatt ttatcataaa
    19621 attcactcag cgcaattcaa gacatttcaa tgacaattaa agatttgaat aaaaaaaaag
    19681 aattaaaagt gataaactaa cagtatcaaa acacagttgc cagaagtaag actggcaccc
    19741 agattaaagg aggcattccc atgacagata cagaccccat caaaagagct catactttga
    19801 ttactgactt aaacaaagcc taccaagcat gcaaacaggc aagcgctgac gacgtccgct
    19861 ttcaggagca attaaactct attcttggtt ttctagccaa ggctgaaaca gtggataatc
    19921 gattcttgat tgaactagaa aaattttacc agacttccag tcttctcatg ggactcagcg
    19981 ctcttgatcc agatgctcca actcgcgccg cttggcgggc ctatgaccgc ttccactttg
    20041 accaagtcaa gaccaag
//
LOCUS       DBEJAU010000040        19938 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC323 isolate 683620
            SAMN38261939-rid24807223.denovo.040, whole genome shotgun sequence.
ACCESSION   DBEJAU010000040 DBEJAU010000000
VERSION     DBEJAU010000040.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261939
            Sequence Read Archive: SRR26833919
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 19938)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 19938)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576303.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576303.1
            Genome Coverage       :: 154x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/19/2025 01:05:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,121
            CDSs (total)                      :: 2,078
            Genes (coding)                    :: 1,943
            CDSs (with protein)               :: 1,943
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 36
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 72 of 135
            Pseudo Genes (incomplete)         :: 63 of 135
            Pseudo Genes (internal stop)      :: 51 of 135
            Pseudo Genes (multiple problems)  :: 46 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..19938
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261939-rid24807223.denovo.040"
                     /strain="GPSC323"
                     /isolate="683620"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            complement(<1..787)
                     /gene="lytB"
                     /locus_tag="ACL29Z_001518"
     CDS             complement(<1..787)
                     /gene="lytB"
                     /locus_tag="ACL29Z_001518"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010976495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endo-beta-N-acetylglucosaminidase"
                     /protein_id="HGR0069804.1"
                     /translation="MNLGEFWYNKINKNRGRRLMKKVRFIFLALLFFLASPEGAMASD
                     GTWQGKQYLKEDGSQAANEWVFDTHYQSWFYIKADANYAENEWLKQGDDYFYLKSGGY
                     MAKSEWVEDKGAFYYLDQDGKMKRNAWVGTSYVGATGAKVIEDWVYDSQYDAWFYIKA
                     DGQHAEKEWLQIKGKDYYFKSGGYLLTSQWINQAYVNASGAKVQQGWLFDKQYQSWFY
                     IKENGNYADKEWIFENGHYYYLKSGGYMAANEWIWDKESWFYLK"
     gene            complement(829..1815)
                     /locus_tag="ACL29Z_001519"
     CDS             complement(829..1815)
                     /locus_tag="ACL29Z_001519"
                     /EC_number="1.3.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013193458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004152 - dihydroorotate dehydrogenase
                     activity [Evidence IEA];
                     GO_process: GO:0006221 - pyrimidine nucleotide
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate dehydrogenase"
                     /protein_id="HGR0069805.1"
                     /translation="MVLFSAQEQLYYKEKIMTTNRLQVSLPGLDLKNPIIPASGCFGF
                     GQEYAKYYDLNLLGSIMIKATTLEPRFGNPTPRVAETPAGMLNAIGLQNPGLEVVLAE
                     KLPWLEREYPNLPIIANVAGFSKQEYAAVSHGISKATNVKAIELNISCPNVDHCNHGL
                     LIGQDPDLAYDVVKAAVEASEVPVYVKLTPSVTDIVTVAKAAEDAGASGLTMINTLVG
                     MRFDLKTRKPILANGTGGMSGPAVFPVALKLIRQVAQTTDLPIIGMGGVDSAEAALEM
                     YLAGASAIGVGTANFTNPYACPDIIENLPKVMDKYGISSLEELRQEVKEFLR"
     gene            complement(1778..2578)
                     /locus_tag="ACL29Z_001520"
     CDS             complement(1778..2578)
                     /locus_tag="ACL29Z_001520"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254684.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA];
                     GO_function: GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA];
                     GO_function: GO:0051537 - 2 iron, 2 sulfur cluster binding
                     [Evidence IEA];
                     GO_process: GO:0006221 - pyrimidine nucleotide
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate dehydrogenase electron transfer
                     subunit"
                     /protein_id="HGR0069806.1"
                     /translation="MNLTCKKRLGVIRLETMKVVAQEEIAPAIFELVLEGEMVEAMRA
                     GQFLHLRVPDDAHLLRRPISISSIDKANKQCHLIYRIEGAGTAIFSTLSQGDTLDVMG
                     PQGNGFDLSDLDEQNQVLLVGGGIGVPPLLEVAKELHERGVKVVTVLGFANKDAVILK
                     TELAQYGQVFVTTDDGSYGIKGNVSVVINDLDSQFDAVYSCGAPGMMKYINQTFDDHP
                     RAYLSLESRMACGMGACYACVLKVPESETVSQRVCEDGPVFRTGTVVL"
     gene            complement(2828..3208)
                     /locus_tag="ACL29Z_001521"
     CDS             complement(2828..3208)
                     /locus_tag="ACL29Z_001521"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398837.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HGR0069807.1"
                     /translation="MVSKMLHTCLRVENLEKSIAFYKDAFGFKELRRRDFPDHAFTIV
                     YLGLEGDDYELELTYNYDHGPYVVSDGFAHIALSTPDLEALHQEHSAKGYEVTEPNGL
                     PGTTPNYYFVKDPDGYKVEVIREK"
     gene            complement(3266..3625)
                     /gene="rplT"
                     /locus_tag="ACL29Z_001522"
     CDS             complement(3266..3625)
                     /gene="rplT"
                     /locus_tag="ACL29Z_001522"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019786714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0000315 - organellar large ribosomal
                     subunit [Evidence IEA];
                     GO_component: GO:0022625 - cytosolic large ribosomal
                     subunit [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L20"
                     /protein_id="HGR0069808.1"
                     /translation="MARVKGGVVSRKRRKRILKLAKGYYGAKHILFRTAKEQVMNSYY
                     YAYRDRRQKKRDFRKLWITRINAAARMNGLSYSQLMHGLKLAEIEVNRKMLADLAVND
                     AVAFTALADAAKAKLGK"
     gene            complement(3677..3877)
                     /gene="rpmI"
                     /locus_tag="ACL29Z_001523"
     CDS             complement(3677..3877)
                     /gene="rpmI"
                     /locus_tag="ACL29Z_001523"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001125942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L35"
                     /protein_id="HGR0069809.1"
                     /translation="MPKQKTHRASAKRFKRTGSGGLKRFRAYTSHRFHGKTKKQRRHL
                     RKASMVHSGDYKRIKAMLTRLK"
     gene            complement(3910..4440)
                     /gene="infC"
                     /locus_tag="ACL29Z_001524"
     CDS             complement(3910..4440)
                     /gene="infC"
                     /locus_tag="ACL29Z_001524"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000848185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003743 - translation initiation factor
                     activity [Evidence IEA];
                     GO_process: GO:0006413 - translational initiation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-3"
                     /protein_id="HGR0069810.1"
                     /translation="MKTIAKQDLFINDEIRVREVRLIGLEGEQLGIKPLSEAQALADN
                     ANVDLVLIQPQAKPPVAKIMDYGKFKFEYQKKQKEQRKKQSVVTVKEVRLSPTIDKGD
                     FDTKLRNARKFLEKGNKVKVSIRFKGRMITHKEIGAKVLAEFAEATQDIAIIEQRAKM
                     DGRQMFMQLAPATDKK"
     misc_feature    complement(4456..4587)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00558"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="ribosomal protein L20 leader region; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF00558"
     gene            complement(4748..5932)
                     /locus_tag="ACL29Z_001525"
     CDS             complement(4748..5932)
                     /locus_tag="ACL29Z_001525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000655955.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HGR0069811.1"
                     /translation="MKDVSLFLLKKVFKSRLNWIILLLFASVLGVTFYLNSQTANSHS
                     LESRLESRIAANERAINENEEKLSQMSDTSSEEYQFAKNNLDVQKNLLTRKTEILTLL
                     KEGRWKEAYYLQWQDEEKNYEFVSNDPTASSGLKMGVDRERKIYQALYPLNIKAHTLE
                     FPTHGIDQIVWILEVIIPSLFVVAIIFMLTQLFAERYQNHLDTAHLYPVSKVTFAISS
                     LGVGVGYVTVLFIGICGFSFLVGSLISGFGQLDYPYPIYSLVNQEVTIGKIQDVLFPG
                     LLLAFLAFIVIVEVVYLIAYFFKQKMPVLFLSLIGIVGLLFGIQTIQPLQRIAHLIPF
                     TYLRSVEILSGRLPKQIDNVNLNWSMGMVLLPCLIIFLLVGILFIESWGSSRKKEVFN
                     RS"
     gene            complement(5936..6523)
                     /locus_tag="ACL29Z_001526"
     CDS             complement(5936..6523)
                     /locus_tag="ACL29Z_001526"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000939891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HGR0069812.1"
                     /translation="MLNLTHVTLKTRQVILQDADFTFKKGRIYGLLAINGSGKTTLFR
                     AMSKLLPLSSGHIAVPPSLFYYESVEWLDGNLSGMDYLRLIKNIWKSDLNFRDEIAYW
                     EMADYISLPIRKYSLGMKQRLVIAMYFLSQAKCWLMDEITNGLDEYYRQKFFDRLAQI
                     DRQEQLVLLSSHYKEELVDICDRVVTIHQGQIEEV"
     gene            complement(6555..6743)
                     /locus_tag="ACL29Z_001527"
     CDS             complement(6555..6743)
                     /locus_tag="ACL29Z_001527"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001810955.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0069813.1"
                     /translation="MTATKSYKYDWNTVLEYSTNYHDHQYAWIPELSRYYSYSEYKVG
                     GGWNYARYKVINYYTGSY"
     gene            complement(6922..9162)
                     /locus_tag="ACL29Z_001528"
     CDS             complement(6922..9162)
                     /locus_tag="ACL29Z_001528"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398664.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0005215 - transporter activity [Evidence
                     IEA];
                     GO_process: GO:0009290 - DNA import into cell involved in
                     transformation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA internalization-related competence protein
                     ComEC/Rec2"
                     /protein_id="HGR0069814.1"
                     /translation="MLQWIKNFSIPLIYLSFLLLWLYYAIFSASYLALLGFVFLLVCL
                     FIQFPWKSAGKVLIICGIFGFWFVFQNWQQSQASQNLADSVERVRILPDTIKVNGDSL
                     SFRGKSNGRAFQVYYKLQSEEEKEAFQALTDLHEIGLEGKLSEPEGQRNFGGFNYQAY
                     LKTQGIYQTLNIKTIQSLQKIGSWDIGENLSSLRRKAVVLIKTHFPDPMRNYMTGLLL
                     GHLDTDFEEMNELYSSLGIIHLFALSGMQVGFFMNGFKKLLLRLGLTQEKLKWLTYPF
                     SLIYAGLTGFSASVIRSLLQKLLAQHGVKGLDNFALTVLVLFIVMPNFFLTAGGVLSC
                     AYAFILTMTSKEGEGLKAVTSESLVISLGILPILSFYFAEFQPWSILLTFVFSFLFDL
                     TFLPLLSILFVLSFLYPVIQLNFIFEWLEGIIRLVSQVTSRPLVFGQPNAWFLILLLI
                     SLALVYDLRKNIKKLTVLCLLITGLFLLTKHPLENEITMLDVGQGESIFLRDVTGKTI
                     LIDVGGKAESYKKIEKWQEKMTTSNAQRTLIPYLKSRGVAKIDQLILTNTDKEHVGDL
                     LEVTKAFHVGEILVSKGSLKQKEFVAELQTTQTKVRSMTVGENLPIFGSQLEVLSPRK
                     MGDGGHDDTLVLYGKFLDKQFLFTGNLEEKGEKDLLKHYPDLKVNVLKASQHGNKKSS
                     SPAFLEKLKPELTLISVGKSNRMKLPHQETLTRLEGINSKVYRTDQQGAIRFKGVDSW
                     KIESVR"
     gene            complement(9146..9796)
                     /locus_tag="ACL29Z_001529"
     CDS             complement(9146..9796)
                     /locus_tag="ACL29Z_001529"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000387331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ComEA family DNA-binding protein"
                     /protein_id="HGR0069815.1"
                     /translation="MEAIIEKIKEYKIIVICTGLGLLVGGFFLLKPAPQTPVKETNLQ
                     VEVAAVSKDLVSEKEVNKEEKEEPVEQDLITVDVKGAVKSPGIYDLPVGSRVNDAVQK
                     AGGLTEQADSKSLNLAQKVSDEALVYVPTKGEEAVSQQTGSGTASSISKEKKVNLNKA
                     SLEELKQVKGLGGKRAQDIIDHREANGKFKSVDELKKVSGIGGKTIEKLKDYVTVD"
     gene            complement(9864..10433)
                     /locus_tag="ACL29Z_001530"
     CDS             complement(9864..10433)
                     /locus_tag="ACL29Z_001530"
                     /EC_number="2.3.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000443767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0016746 - acyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HGR0069816.1"
                     /translation="MESIFVKLAQYPSIETERLLLRPVTLDDAEAMFDYASDKGNTRY
                     TFPTNQSLEETKNNIAQFYLANPLGRWGIELKSNGQFIGTIDLHKIDSVLKKAAIGYI
                     INKKYWNQGLTTEANRAVIELAFEKIGMNKLTALHDKDNPASGKVMEKSGMRFSHAEP
                     YACMDQHEKGRIVTRVHYVLTKEDYFANK"
     gene            10610..11721
                     /gene="ald"
                     /locus_tag="ACL29Z_001531"
                     /pseudo
     CDS             10610..11721
                     /gene="ald"
                     /locus_tag="ACL29Z_001531"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003018852.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_function: GO:0000286 - alanine dehydrogenase activity
                     [Evidence IEA];
                     GO_process: GO:0042853 - L-alanine catabolic process
                     [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="alanine dehydrogenase"
     gene            complement(12022..12347)
                     /locus_tag="ACL29Z_001532"
                     /pseudo
     CDS             complement(12022..12347)
                     /locus_tag="ACL29Z_001532"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003032802.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="TfoX/Sxy family protein"
     gene            complement(12350..12850)
                     /locus_tag="ACL29Z_001533"
     CDS             complement(12350..12850)
                     /locus_tag="ACL29Z_001533"
                     /EC_number="2.3.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000566985.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0016746 - acyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HGR0069817.1"
                     /translation="MIDQLSKYYSCRILTEKDIPSILSLYESNPLYFQHCPPEPNFAT
                     VKEDMLCLPEGKAKADKFFVGFWNGFDLVAVMDFVYAYPDEETVFIGLFMVDQAYQRK
                     GIGSHIVTEALAYFAKNFRKARLAYVKGNPQSQHFWEKQGFKSIGCEVKQELYTVVIV
                     EQSLED"
     gene            complement(13043..14011)
                     /locus_tag="ACL29Z_001534"
     CDS             complement(13043..14011)
                     /locus_tag="ACL29Z_001534"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001860490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PhoH family protein"
                     /protein_id="HGR0069818.1"
                     /translation="MKEHSIDIQLSHPDDLFHLFGSNERHLRLMEEELDVVIHARTEI
                     VQVLGEESACEEARQVIQALMVLVNRGMTVGTPDVVTAISMVKNDEIDKFVALYEEEI
                     IKDNTGKPIRVKTLGQKLYVDSVKQHDVTFGIGPAGTGKTFLAVTLAVTALKRGQVKR
                     IILTRPAVEAGESLGFLPGDLKEKVDPYLRPVYDALYQILGKDQTTRLMEREIIEIAP
                     LAYMRGRTLDDAFVILDEAQNTTIMQMKMFLTRLGFHSKMIVNGDISQIDLPRNVKSG
                     LIDAQEKLKNIHQIDFVHFSAKDVVRHPVVAQIIRAYEYSTEVAHD"
     gene            complement(14097..14312)
                     /locus_tag="ACL29Z_001535"
     CDS             complement(14097..14312)
                     /locus_tag="ACL29Z_001535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002894860.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YozE family protein"
                     /protein_id="HGR0069819.1"
                     /translation="MRKSFYTWLMTERNPKSNSPKAILADLAFEEAAFPKHTDDFDEV
                     SRFLEEHASFSFNLGDFDSIWQEYLEH"
     gene            complement(14321..15175)
                     /gene="cvfB"
                     /locus_tag="ACL29Z_001536"
     CDS             complement(14321..15175)
                     /gene="cvfB"
                     /locus_tag="ACL29Z_001536"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001095444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding virulence regulatory protein CvfB"
                     /protein_id="HGR0069820.1"
                     /translation="MNTNLASFIVGLIIDENDRFYFVQKDGQTYALAKEEGQHTVGDT
                     VKGFAYTDMKQKLRLTTLEVTATQDQFGWGRVTEVRKDLGVFVDTGLPDKEIVVSLDI
                     LPELKELWPKKGDQLYIRLEVDKKDRIWGLLAYQEDFQRLARPAYNNMQNQNWPAIVY
                     RLKLSGTFVYLPENNMLGFIHPSERYAEPRLGQVLDARVIGFREVDRTLNLSLKPRSF
                     EMLENDAQMILTYLESNGGFMTLNDKSSPDDIKATFGISKGQFKKALGGLMKAGKIKQ
                     DQFGTELI"
     gene            complement(15235..15792)
                     /gene="frr"
                     /locus_tag="ACL29Z_001537"
     CDS             complement(15235..15792)
                     /gene="frr"
                     /locus_tag="ACL29Z_001537"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006148672.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008135 - translation factor activity, RNA
                     binding [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome recycling factor"
                     /protein_id="HGR0069821.1"
                     /translation="MANIIIEKAKERMTQSHQSLAREFGGIRAGRANASLLDRVHVEY
                     YGVETPLNQIASITIPEARVLLVTPFDKSSLKDIERALNASDLGITPANDGSVIRLVI
                     PALTEETRRDLAKEVKKVGENAKVVVRNIRRDAMDEAKKQEKAKEITEDELKTLEKDI
                     QKVTDDAVKHIDDMTANKEKELLEV"
     gene            complement(15801..16538)
                     /gene="pyrH"
                     /locus_tag="ACL29Z_001538"
     CDS             complement(15801..16538)
                     /gene="pyrH"
                     /locus_tag="ACL29Z_001538"
                     /EC_number="2.7.4.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000013002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0033862 - UMP kinase activity [Evidence
                     IEA];
                     GO_process: GO:0006221 - pyrimidine nucleotide
                     biosynthetic process [Evidence IEA];
                     GO_process: GO:0015949 - nucleobase-containing small
                     molecule interconversion [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UMP kinase"
                     /protein_id="HGR0069822.1"
                     /translation="MANPKYKRILIKLSGEALAGERGVGIDIQTVQTIAKEIQEVHSL
                     GIEIALVIGGGNLWRGEPAAEAGMDRVQADYTGMLGTVMNALVMADSLQQVGVDTRVQ
                     TAIAMQQVAEPYVRGRALRHLEKGRIVIFGAGIGSPYFSTDTTAALRAAEIEADAILM
                     AKNGVDGVYNADPKKDKTAVKFEELTHRDVINKGLRIMDSTASTLSMDNDIDLVVFNM
                     NQSGNIKRVVFGENIGTTVSNNIEEKE"
     gene            complement(16622..17956)
                     /gene="trmFO"
                     /locus_tag="ACL29Z_001539"
     CDS             complement(16622..17956)
                     /gene="trmFO"
                     /locus_tag="ACL29Z_001539"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000083696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA];
                     GO_process: GO:0008033 - tRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="methylenetetrahydrofolate--tRNA-(uracil(54)-
                     C(5))-methyltransferase (FADH(2)-oxidizing) TrmFO"
                     /protein_id="HGR0069823.1"
                     /translation="MSQSYINVIGAGLAGSEAAYQIAERGIPVKLYEMRGVKSTPQHK
                     TDNFAELVCSNSLRGDALTNAVGLLKEEMRRLGSVILESAEATRVPAGGALAVDRDGF
                     SQMVTEKVVNHPLIEVVRDEITELPTDVITVVATGPLTSDALAEKIHALNNGDGFYFY
                     DAAAPIIDVNTIDMSKVYLKSRYDKGEAAYLNAPMTKQEFMDFHEALVNAEEAPLNSF
                     EKEKYFEGCMPIEVMAKRGIKTMLYGPMKPVGLEYPDDYTGPRDGEFKTPYAVVQLRQ
                     DNAAGSLYNIVGFQTHLKWGEQKRVFQMIPGLENAEFVRYGVMHRNSYMDSPNLLEQT
                     YRSKKQPNLFFAGQMTGVEGYVESAASGLVAGINAARLFKEESEVIFPETTAIGSLAH
                     YITHADSKHFQPMNVNFGIIKELEGERIRDKKARYEKIAERALADLEEFLTV"
     gene            complement(18201..18473)
                     /locus_tag="ACL29Z_001540"
     CDS             complement(18201..18473)
                     /locus_tag="ACL29Z_001540"
                     /inference="COORDINATES: protein motif:HMM:NF036719.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit delta"
                     /protein_id="HGR0069824.1"
                     /translation="MFTCFIIHRTTIPYFVSQEVYWKVRNIEAEAIRRNCERGAIFSG
                     KIKYHEDSQFKGDHYVECYAVLDNTVIARDRITVPIDPLCGKDFIE"
     gene            18450..19210
                     /locus_tag="ACL29Z_001541"
                     /pseudo
     CDS             18450..19210
                     /locus_tag="ACL29Z_001541"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS5 family transposase"
     gene            complement(19199..19852)
                     /locus_tag="ACL29Z_001542"
     CDS             complement(19199..19852)
                     /locus_tag="ACL29Z_001542"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000345255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiator protein A"
                     /protein_id="HGR0069825.1"
                     /translation="MDFEYFYNREAERFNFLKVPEILVDREEFRGLSAEAIILYSILL
                     KQTGMSFKNNWIDKEGRVFIYFTVEEIMKRRNISKPTAIKTLDELDVKKGIGLIERVR
                     LGLGKPNIIYVKDFMSIFQVKENDLQKSKNLTSEVKDFNLRSKENELQEVKNLDSNYN
                     YIENNKSKYSKREYSFGENGLGTFQNVFLAAEDISDLQIIMNSQLENYIRLPAKLES"
BASE COUNT         5775 a         4463 c         3658 g         6042 t
ORIGIN      
        1 acttgaggta aaaccaagat tccttatccc aaatccattc attggctgcc atgtagccac
       61 cggattttag ataataatag tgaccattct cgaaaatcca ttctttatca gcatagtttc
      121 cattttcttt gatgtaaaac caagattggt attgtttgtc aaaaagccaa ccttgctgca
      181 ctttggcacc actagcattc acataagctt gattaatcca ctgacttgtc agtagataac
      241 caccggattt gaaataatag tccttccctt taatttggag ccattctttc tctgcgtgct
      301 gtccatctgc tttgatataa aaccaagcat cgtattgaga atcatagacc cagtcttcta
      361 ttactttggc acctgttgca ccaacatagg aagttcctac ccaagcattt cttttcatct
      421 ttccatcttg gtcaagataa taaaaggctc ccttgtcttc tacccattct gatttggcca
      481 tatagccacc agatttgagg taaaaatagt cgtcaccttg ctttagccat tcattttcag
      541 catagttagc atctgctttt atatagaacc aagattgata atgagtatca aaaacccact
      601 cattcgctgc ttgactgcca tcttctttca gatactgttt tccttgccaa gtaccatcac
      661 tagccattgc accttctgga ctagctaaga aaaatagcag agctaaaaaa ataaatctta
      721 ctttcttcat taaccttctt cctctgttct tatttatttt attgtaccaa aattctccta
      781 aattcatatt acaaactaat aaaaaatcaa gaacagattg attgcagttt acctcagaaa
      841 ctcttttact tcctgacgga gttcttccag actgctaata ccgtatttat ccatgacttt
      901 tggtaaattt tcgatgatgt cagggcaggc ataaggattg gtaaagttag ctgttccaac
      961 tccgatagca gatgccccag ccagatacat ttctagggca gcttcagccg aatccactcc
     1021 ccccattcca atgataggca ggtctgttgt ttgggctact tggcggatga gtttgagggc
     1081 tactggaaag actgctggac ctgacattcc acctgttcca ttggccaaga ttggttttct
     1141 ggttttgagg tcaaagcgca ttccaaccag agtattgatc atggtcaagc cacttgctcc
     1201 cgcatcttct gcagcttttg cgacagtaac gatatcggtc acactcgggg ttaatttgac
     1261 ataaactggc acttctgagg cttccacagc tgctttcacc acatcataag ccaaatctgg
     1321 atcttgacca atcaaaagtc catgattaca gtggtcaaca ttgggacaag aaatattgag
     1381 ctcgatagct tttacattag ttgccttgga aatcccatga gaaacagctg catactcttg
     1441 ttttgaaaaa ccagctacat tggcaataat aggaagattt ggatattctc tttccagcca
     1501 aggtagcttt tcagccaaaa caacctctaa accaggattt tgcaagccaa ttgcattgag
     1561 cataccagca ggcgtctctg ctactcttgg agttgggttc ccaaaacgtg gttcaagggt
     1621 tgtcgccttg atcataatag aacctaaaag gtttaaatca tagtacttgg catactcttg
     1681 tccaaagcca aaacagcctg atgctggaat aatcggattt ttcaaatcca aaccaggtag
     1741 agacacttgt aatcgatttg tagtcataat tttctcctta taatacaact gttcctgtgc
     1801 ggaaaacagg accatcttca cagacgcgtt ggctgaccgt ctcgctttct ggtactttta
     1861 gaacacaggc atagcaagct cccatcccac aagccatacg agattccaga gataaatagg
     1921 ctcttgggtg atcatcaaag gtttgattga tatacttcat cattcctgga gccccacacg
     1981 agtaaacagc atcaaactga ctatctaaat cattgataac aacggaaaca tttcccttga
     2041 tgccataaga accatcatct gtcgttacaa agacctgacc atactgagcc aattccgttt
     2101 tcaaaataac agcatcctta ttagcaaaac cgaggactgt cactactttc actccacgtt
     2161 catgcaattc cttggccacc tcaagcaagg gtggaacacc aatcccacca ccaacaagga
     2221 gaacctgatt ctgctcatca aggtcagaca agtcaaaacc atttccctga ggccccatca
     2281 catcaagagt gtctccctga cttaaggttg aaaaaattgc agtcccagct ccctcaatcc
     2341 gataaatgag gtgacactgc ttgtttgcct tgtcaataga cgaaattgaa ataggacgac
     2401 gtaagagatg ggcatcgtct ggtacacgca gatgaagaaa ttggcctgct cgcatggctt
     2461 caaccatttc tccttctagg actaattcaa agattgctgg cgcgatttcc tcttgtgcaa
     2521 ccaccttcat ggtttccaac cgaatgacac ccaaacgctt cttacatgtg agattcataa
     2581 cttttcctcc ttaaatttta aggggaccag ataaagaaaa gaccttgcta gtgcaaggcc
     2641 tcagttaaaa tcgtacaaca caagagagca cactcaaaag gtctcctcta gaaaattgca
     2701 ctattctttt atctgacacc ttgtgagtct ctctggactc cccttaaagg ttgaattttt
     2761 attagtatac tctttcagct aaaaaaagtc aagtagaaaa cgaatattct acttaacttg
     2821 cacgaaatta tttttcacga atgacttcga ccttatatcc atcagggtct ttaacaaagt
     2881 aatagtttgg tgtagttcct ggtagaccat ttggctcagt cacttcatag ccttttgcac
     2941 tgtgttcttg atgaagtgcc tcaagatcag gtgtactgag ggcgatatgg gcaaacccat
     3001 cactaaccac atacggaccg tgatcgtagt tataagtcaa ctccaactca taatcatcac
     3061 cctcaagacc tagatagaca atcgtgaagg catggtctgg aaaatctctg cgacgcaatt
     3121 ctttaaaacc aaaagcatct ttataaaatg cgattgattt ttcaagattt tctactcgta
     3181 agcaagtgtg tagcattttt gaaaccatat ctttctcctt tatttttaaa aagactggac
     3241 aatcctgttc cagtctcatc agttgttatt taccaagttt tgctttagct gcatctgcaa
     3301 gagctgtgaa agctactgca tcgttaacag ccaagtcagc aagcatttta cggttaactt
     3361 caatctcagc caatttcaaa ccatgcatca attgtgagta tgaaagtccg ttcatacgag
     3421 ctgccgcatt gatacgagta atccacaatt tgcggaagtc acgttttttc tgacgacggt
     3481 cacggtatgc atagtagtaa gagttcatta cttgttcttt tgcagtacgg aacaagatgt
     3541 gtttagctcc atagtaacct tttgctaatt taagaatacg tttacgacgt ttgcgtgata
     3601 caacgccacc tttaacacgt gccatgtttt atttcctcca aatatttcct agaattgttt
     3661 acttacagtc aagctattat ttcaagcgag taagcattgc tttgatacgt ttgtaatctc
     3721 ctgaatgcac catagatgct ttacgaagat gacgacgttg tttcttagtt tttccgtgga
     3781 aacggtgaga agtgtaagca cggaaacgtt taagtccacc agaacctgta cgtttgaaac
     3841 gtttagctga tgcgcggtgt gttttttgtt ttggcatgat tttttctcct ttatttaact
     3901 ttctgacaat tattttttgt cagtcgctgg cgccaattgc atgaacattt gacgtccatc
     3961 cattttagca cgttgttcga tgatggcaat atcttgagtt gcttcagcaa actcggctaa
     4021 aacttttgca ccaatctctt tatgggtaat catacgaccc ttaaagcgaa tagatacctt
     4081 aactttattt cctttttcaa ggaacttacg tgcattacga agttttgtat caaagtcacc
     4141 cttgtcaata gttggactta gacgaacttc tttcacagta acaacgcttt gttttttacg
     4201 ttgttctttt tgcttcttct ggtactcaaa tttgaactta ccgtagtcca taatttttgc
     4261 aacaggcggt ttggcttggg gttgaatcaa tactaggtca acattagcgt tatcagccaa
     4321 agcttgcgct tcactgagtg gcttgatgcc tagctgttct ccctcaagac caatcaagcg
     4381 aacttcacgt acacgaatct catcattgat gaataagtct tgctttgcta tggttttcac
     4441 ctcttttgtt ttattagaga aaaacaatag cggactcgta aatatacaag cccgcacgtt
     4501 atgatagcgt ttcttcgaaa cttttcatcc gtagggccag gcaacttaat gtcacaaggc
     4561 gagaagctct cacttctgct tttctcaact tttaaatgat accaagtttt ctagctcttg
     4621 tcaagataaa aagttatttt tttgaaaagt ttgtgtttgt attttggttt ggttttcgaa
     4681 tcaaaaagag agaatcaagt tgattccctc tctatgttag tttttcctta acttccttat
     4741 aagaatgcta agacctatta aaaacttcct ttttacgtga acttccccag ctttcaataa
     4801 atagaatccc cactagcaaa aagataatca gacaaggaag taagaccatt cccatgctcc
     4861 aatttagatt gacattatca atttgcttag gtaatcttcc agataaaatc tccactgaac
     4921 gcaagtaagt aaagggaatc agatgtgcaa tcctttgaag aggctgaatg gtttggatgc
     4981 caaacaataa accaacaatc ccaatgagtg aaagaaagag gacaggcatt ttttgcttaa
     5041 aaaagtaagc aatcaagtac acaacttcca caatgacgat aaaggctaag aaagctaaga
     5101 gcaagccagg aaataataca tcttgtattt tcccaatagt tacttcttga ttcactaagc
     5161 tataaattgg gtagggataa tctaactgtc caaaaccact tatcagactt cccactagaa
     5221 aagaaaagcc acagattccg ataaacagca cagttacata tcccactcca actccaagag
     5281 aggatattgc aaatgtcact tttgaaacag gatataagtg agctgtgtcc agatgatttt
     5341 gatatctttc tgcaaatagt tgtgttagca taaaaataat cgcaaccaca aacaagcttg
     5401 ggatgataac ctctaaaatc cagacaatct gatcaatccc gtgggtcgga aactccaaag
     5461 tatgtgcttt tatgttcaag ggatacaggg cttggtaaat cttccgttcg cggtcaaccc
     5521 ccatttttaa gccagagcta gcagtcgggt catttgatac aaattcataa ttcttctctt
     5581 catcttgcca ctgcagatag taggcttctt tccagcgccc ttcttttagt aaagtcagaa
     5641 tttctgtctt tcgcgtcaaa agattttttt gcacgtctaa attattttta gcaaactggt
     5701 attcctccga gctggtatca gacatttggg agagtttctc ttcattttca ttgatagccc
     5761 tctcgttggc tgcaatgcga ctttccaacc tgctctccaa gctgtgtgag tttgcagtct
     5821 gactatttaa ataaaaggta acaccgagta cagatgcaaa taaaagtaag ataatccagt
     5881 ttaaacgact tttgaaaact tttttcaata aaaatagact aacatctttc ataaactaaa
     5941 cctcttctat ctgcccctga tgaatggtta ctactctatc gcagatatca accaactctt
     6001 ccttatagtg ggaacttaaa agaaccagct gttcttgtct atcgatttgt gctagcctat
     6061 caaaaaactt ctgtcgataa tactcgtcta agccatttgt aatctcatcc atgagccagc
     6121 atttggcctg actgagaaaa tacatagcaa tcaccaagcg ttgcttcatg cctaaggaat
     6181 acttgcggat gggaagactg atatagtcag ccatttccca gtaggcgatt tcatctctga
     6241 agtttaggtc tgacttccag atgtttttta tgagacgaag gtagtccatc ccacttaagt
     6301 ttccatccag ccattcaacg ctctcataat aaaacaaaga aggaggaact gcgatgtgtc
     6361 cactactaag gggaagcaac ttgctcatag ctcggaatag tgtcgtcttt cccgagccat
     6421 tgatagcaag aaggccataa atcctaccct ttttaaaggt aaaatccgca tcttgcaaga
     6481 tgacttgtcg cgtttttaag gtaacatgag taagatttaa catatccagc cctccttttc
     6541 tcactcttta aggattaata acttccagta tagtagttta tgaccttata acgagcgtag
     6601 ttccagcctc cgccaacttt atactcagaa tagctgtaat aacgagacaa ttccggaatc
     6661 caagcatact gatggtcgtg atagttggta ctatattcca aaaccgtatt ccaatcatac
     6721 ttgtaacttt tagtggctgt cacagcagat acactggact gaagaagacc aatagattat
     6781 aaactaacta ataaaacaac ttttgctgat ttttaacgat tttatatcct caatattgaa
     6841 tacgttttca ttataccgtt tttatcatta ttatgcaaca aatttttagt ttatttcact
     6901 aatctacaac atttatcctt cctatcgaac actttcgatt ttccaactat ccaccccctt
     6961 aaaacgtata gctccttgct ggtcagttcg ataaactttg ctattgatac cttccagtcg
     7021 tgtcaatgtt tcctgatggg ggagtttcat tcgattgctc tttccaactg agataagagt
     7081 aagctctggt ttgagttttt ctagaaaggc tggacttgat gattttttat tgccatgttg
     7141 gctagctttc aaaacattta ctttcaagtc tggatagtgc ttcagcaagt ccttctctcc
     7201 tttctcctcc aaatttcccg tgaagagaaa ttgcttatcc aagaatttcc catacagaac
     7261 tagggtgtca tcgtgtcctc catctcccat tttccttgga gatagaactt ctaactgact
     7321 tccaaaaatg ggcaagttct cccctactgt catactacgc acctttgttt gagtcgtctg
     7381 tagttctgcc acaaattcct tctgcttcaa actgcctttt gatactaaaa tctcccctac
     7441 atggaaagcc ttggtcacct ctaacaaatc tccgacatgt tccttgtccg tatttgtcaa
     7501 aatcagctgg tcaatcttag ctactcctcg acttttgaga tagggaatca aggttcgctg
     7561 ggcattgctg gtcgtcatct tttcttgcca tttttcgatt ttcttataag attctgcctt
     7621 accacctaca tctatgagaa tggttttccc agttacatcc cgtaggaaaa tactttctcc
     7681 ttgccccaca tccagcatgg tgatttcatt ttccagtgga tgcttggtca ggagaaagag
     7741 ccctgtaatc aataagcaca ataccgttag ctttttaatg ttttttctca aatcatagac
     7801 caaagccaag gaaattaaca ataggattaa aaaccatgca ttgggttgtc caaagaccag
     7861 aggtctactt gtcacctgtg acaccaagcg aataatgccc tccaaccatt caaagataaa
     7921 gttcagctga atgactggat agagaaagga aaggacaaat aaaatagaca agagcggtaa
     7981 gaaggtcaag tcaaatagaa aggaaaagac aaaggtcaaa aggatagacc aaggttgaaa
     8041 ttccgcaaaa tagaaggata gaatgggcaa tatgcccaag gagatgacta gactttcact
     8101 agtaacagcc ttgagcccct ccccttcttt gctggtcatg gtcaggataa aagcataagc
     8161 gcaggacaag actcctcctg ctgtcaagaa aaagtttggc atgacaataa agaggacaag
     8221 caccgtcaag gcaaaattat ccaagccctt aaccccatgt tgagccagta gcttttgcaa
     8281 gagactgcga ataaccgatg ctgaaaatcc agttagtccc gcatagataa gggaaaaggg
     8341 ataagtcagc catttcaact tttcttgggt caagcccaat cgcaagagaa gtttcttaaa
     8401 tccattcatg aaaaaaccta cctgcatacc agatagggca aagaggtgga taattcctag
     8461 actggaataa agctcattca tctcctcaaa gtcggtgtcc agatgtccca gcaagagtcc
     8521 tgtcatgtaa ttgcgcatag ggtctggaaa gtgcgtctta atcaaaacca cagcctttcg
     8581 acgtaaactg gacaagtttt ctcctatatc ccaactgcca atcttttgaa gtgactggat
     8641 tgttttgata ttgagagtct ggtaaattcc ctgagtcttc agataggctt ggtaattaaa
     8701 gccaccaaaa tttctctgcc cttctggctc cgaaagcttc ccttctagtc ctatctcatg
     8761 caggtcggtt aaagcttgaa aggcttcttt ctcctcctcg gactggagtt tataatagac
     8821 ttggaaagca cgaccgttag acttgccacg aaaggataga ctatcaccat taaccttaat
     8881 agtatcaggc aaaatccgta ccctttcaac agaatccgcc agattttgac tcgcttgact
     8941 ctgttgccaa ttttgaaaaa caaaccaaaa tccaaagatt ccgcaaatta ttagaacttt
     9001 accagcagat ttccacggaa attggataaa gagacagact agcagaaaaa caaagcccaa
     9061 caaagcaaga taagatgctg agaaaatagc gtaataaagc caaagtaata gaaaactcag
     9121 gtaaattagg ggaatagaga aattcttaat ccactgtaac atagtcttta agcttttcta
     9181 ttgttttgcc accaatgcca gagaccttct tgagctcgtc tactgacttg aacttgccat
     9241 ttgcctcacg atggtcgata atgtcctgag ctcgttttcc tcccagtccc ttgacctgct
     9301 tgagttcttc cagactggcc ttgttgagat tgaccttctt ttccttgctt attgaagaag
     9361 ctgtccccga accagtctgt tgactaactg cttcttctcc cttagtagga acgtaaacca
     9421 gagcctcatc actaactttc tgagctagat tgagcgactt gctgtctgct tgctctgtca
     9481 agccaccagc cttctgaaca gcatcattga ctcgactacc tacaggcaag tcataaatcc
     9541 ctggcgattt gacagcacct ttgacatcta ctgtgattag atcttgttca actggttctt
     9601 ccttctcttc cttgttcact tccttttcgg ataccaaatc cttggaaaca gctgcaactt
     9661 caacctgcaa attcgtttcc tttacaggtg tttgtggagc tggctttagc aggaaaaatc
     9721 cgcctacaag caagcccaga ccagtacaga tgacgatgat tttatactct ttgattttct
     9781 cgataattgc ttccatattt tctcctctct tagattattc gtaagaggaa gaaaaaacag
     9841 tcgaaaaatt tcttttcaac tgcttattta tttgcaaaat agtcttcctt ggtcaagaca
     9901 taatgaactc ttgtcacgat tcggcctttt tcatgctggt ccatacaagc atatggttct
     9961 gcatgggaaa aacgcatgcc tgatttctcc atgacctttc ctgacgcagg attgtcctta
    10021 tcgtgaaggg cagtcaactt attcatccct atcttctcaa aagctagctc aatcacagca
    10081 cgattggctt ctgtcgttaa tccttgattc caatactttt tattgataat gtagccaata
    10141 gctgccttct taagaacaga atcaatcttg tgcaagtcaa tggttccaat aaactgacca
    10201 ttgcttttta gttctattcc ccaacgtccc aagggattag ccaaatagaa ctgagcaatg
    10261 ttattcttgg tttcttccaa gctttgattg gttggaaaag tgtaacgtgt attacccttg
    10321 tccgaggcat agtcaaacat tgcttccgca tcatccaaag ttacaggtct aagcaataaa
    10381 cgctccgttt ctatagacgg atactgggca agttttacaa aaattgattc catacttttc
    10441 caaccaatca aagcttgatt ttcactagtc tagcataaaa aatttggatg acaagttttt
    10501 cttgattttt gaagcggttt catatacaat gaaaccgtca catttttgat ttatgaactg
    10561 gaatgtgaca accaaaacaa gaccgtcaat tgaaaggtag gttatctcaa tgttaatcgg
    10621 aatcccaaaa gaaattaaaa ataacgaaaa ccgtgtcgcc ctcacacctg caggtgttca
    10681 tagcttagtt agtcgtggtc atcgtgtcct tatcgaaaca aatgctggtc tcggttctgg
    10741 ctttactgat gctgactatc aaaagcaagg agctgagatt gtcgctactg ctggtgaagc
    10801 ttgggcagca gagttggttg tgaaagtaaa agaaccttta agttctgaat acggttactt
    10861 gcgcgacgat cttcttctct tcacctactt gcacatggcc gctgctccag aattagcaga
    10921 tgctatgtta gcagcaaaaa caacaggaat tgcctatgaa actgttcgtg acaatcaagg
    10981 acaactaccg ctcctcgttc ctatgagtga ggttgcaggt cgtatggctg tttaaatcgg
    11041 agctcacttc cttactaagc aagctggtgg ctctggtgtt ctacctggtg gtgtaccagg
    11101 tgttccaaaa ggaaaagtaa ctatcatcgg tgatggtgtc gtcggtacac atgctgcccg
    11161 catcgccctt ggtcttggtg ctcaagtgac tattttagat attagtgcca agcgtctctc
    11221 agttctagaa gaagtctttg gaagtcaaat tcaaactctt atatctaatt cattcaacat
    11281 tgaagcaagt atgagagatg ctgatgtggt gattggagcc attctcatcc ctggtgcaaa
    11341 agcaccggaa ttggtgacag atgagatggt caaacaaatg cgtccaggct ctgtatcgtt
    11401 gacattgctg ttgaccaagg tggccttatc gaaacagctg accgtgtgac aacgcacgat
    11461 gaacccgtct atgaaaaaca cggtgttctc cactatgccg ttgccaatat ccctggtgcg
    11521 gttgcccgca cttcaaccat cgccctaacc aatgtcactc ttccttatat cgaagctttg
    11581 gctggcaaag gattcgcaca agcaatctct gaagatgaag gcttgcgtca aggtgtgacc
    11641 acttatcaag gttacttgac tagcctacca gttgctcaag gacttaatcg tgactacact
    11701 gatatcaatg atttagtata aattttgaaa agaaaagggt gacttcgcaa gtcctaccca
    11761 ctgtgctttg tgtcatcagc tattacatcg ttggtttatt gtactgtata ctttgcaact
    11821 ggagactttc gttccagact caattgtgca taagaaactc taaattgaat aaagtcaaca
    11881 gagtttcgcc caaccacttc gtcttgtaat gacaattata taaaccaaag gaagctgagc
    11941 tctttagtcc cagcttcttt ttatatataa aattttaccc gtgcaaagac agggccttag
    12001 cagacttctt ttttacttcg ttcacccttg ctttttcttt ttaggtttgg gcgttggcag
    12061 ttggttatac atagctaaaa tcaggtctta tagaaacatc ttattatcaa gttcttccac
    12121 tcaaatcatt tctttggcac ctttgtatgg aaactcaaaa gaagattggt caatcttatc
    12181 taagactgct tgcacgggtt taactaaaag cgatcgtcat aaatgccgcc aataatcttg
    12241 ccgcggaagt aaagaatata ctcccccatc atggaacggt aagtcacatc atctaatcct
    12301 gataattgtt ccaaaacaaa ttccaaatag ttcttacttg atgccatttc taatcttcta
    12361 ggctctgttc aacgataaca accgtataga gttcttgctt aacctcgcat ccaattgatt
    12421 taaagccctg cttttcccaa aaatgctgag attgcggatt tcccttaaca taagccaaac
    12481 gtgcctttcg aaagttctta gcaaaataag ctagtgcttc tgtcacaata tgactaccaa
    12541 tccctttcct ctgataggct tgatcaacca taaacaaacc aataaaaaca gtctcctcat
    12601 caggatatgc atagacaaaa tccataacag ccacaaggtc aaatccattc caaaatccaa
    12661 caaaaaactt atcagcctta gctttacctt caggtagaca aagcatgtcc tcttttacag
    12721 ttgcaaaatt tggctctggt ggacaatgct gaaaatacag aggattactt tcatataaag
    12781 ataaaatact tggaatatcc ttttcagtta gtatcctaca actgtaatac ttagatagtt
    12841 ggtcaatcat cttttcaaat tcctactttc ttgtgtcctg tgattatgac acaggaagat
    12901 gcactgatcg tcatcagcca cataaaagtt ctttccatcg tgcctaatcg ttgtctcaaa
    12961 cctttggata aaacctttag cctatacaac tggattttcc tctctcaaaa gtatattctt
    13021 ttgcaggcga acttcctcaa aatcagtcgt gtgcaacttc agtagaatat tcataggctc
    13081 ggataatctg agcgacaaca ggatggcgaa ccacatcctt ggctgaaaaa tgaacaaagt
    13141 caatctgatg gatgttcttg agtttctctt gagcatcaat caaaccggac ttgacattac
    13201 gtggcaggtc aatctgacta atatctccat tgacaatcat cttagaatga aaacctaaac
    13261 gagtcaagaa catcttcatc tgcatgatgg tcgtattttg cgcctcatcg agaatgacaa
    13321 aggcatcatc caaggtccgt ccacgcatat aggcaagggg cgcaatctcg ataatttcac
    13381 gctccatgag tcgagttgtt tggtctttcc ccagaatctg atacaaggca tcataaacag
    13441 gtctaaggta aggatctacc ttctccttaa gatcacccgg aagaaaacct agactctctc
    13501 ctgcttccac cgctggacgt gtcaagataa tccgcttgac ttgcccacgt ttaagggcag
    13561 tcactgccaa agtaactgca agaaaggtct tccccgtccc tgcaggccca attccaaagg
    13621 tcacatcatg ctgtttgaca ctgtccacat aaagtttttg acctaaggtt ttgacgcgga
    13681 tcggtttccc agtattatct ttgataattt cttcttcgta aagggcgaca aacttatcaa
    13741 tttcatcgtt tttgaccatg ctaattgcag tcaccacatc tggcgtacca acggtcatcc
    13801 cacggttcac caagaccatg agagcttgaa taacctgacg ggcttcctca caagcagact
    13861 cttctcccaa aacctggaca atctccgtac gagcatgaat caccacatcc agctcttctt
    13921 ccatcaaacg aagatggcgc tcattggaac caaaaagatg aaacaggtca tctggatgac
    13981 tcagttgaat gtctattgaa tgttccttca aataaagaac ctctctaatc cttttatttc
    14041 tttttattat agcagaggga tggagaaatt actagcccaa acccaatgaa taaatgctag
    14101 tgttctagat attcctgcca aatgctgtca aaatctccta ggttaaaaga gaaactggca
    14161 tgctcctcca aaaagcgact gacctcatca aaatcatctg tatgttttgg aaaagctgcc
    14221 tcttcaaaag cgaggtctgc caaaattgct ttgggactgt tacttttagg attgcgctcg
    14281 gtcatgagcc aagtgtaaaa tgattttctc ataagcctcc ctaaatcaac tctgtaccaa
    14341 actggtcctg cttgatttta ccagccttca taagaccacc taaagctttc ttgaactgac
    14401 ctttagaaat gccaaaggtt gccttgatgt cgtctggaga tgacttgtca tttaaggtca
    14461 tgaaaccgcc attgctttcc aaataagtca aaatcatctg agcatcgttt tccaacattt
    14521 caaaggagcg tggtttgagg gagaggttca aagtgcggtc cacttcacgg aaaccaataa
    14581 cgcgcgcatc taatacttgc cccaaacgtg gctctgcgta acgctcgcta ggatgaataa
    14641 aaccaagcat attattttct ggtaggtaaa caaaagttcc tgacagcttg agacggtaaa
    14701 caatggctgg ccagttttgg ttctgcatgt tgttgtaggc aggacgagcg agacgttgga
    14761 agtcttcttg ataagccaag aggccccaga tacggtcttt cttatccact tcaagacgga
    14821 tgtagagttg gtcgcccttc ttaggccaga gttccttgag ctcagggaga atatcgagtg
    14881 acacaacgat ttccttgtca ggaaggcctg tatccacaaa gacacccaag tccttacgaa
    14941 cctctgtgac acgtccccaa ccaaattggt cctgagtggc agtcacttct aaggttgtca
    15001 ggcggagttt ttgcttcata tccgtgtatg caaaaccttt gaccgtatcc cctactgtat
    15061 gttggccctc ttccttagca agagcatagg tttgaccatc cttttgcaca aagtaaaaac
    15121 ggtcattttc atcgatgatc agtccaacga taaaacttgc aagatttgta ttcatatttc
    15181 cttctttcga ataaaactca gccagcaatg ccaactgagt ttttctgttt atttttagac
    15241 ttccaaaagt tctttctctt tgttagcagt catgtcgtcg atgtgtttaa cagcatcgtc
    15301 tgttactttt tgaatatctt tttcaagagt cttcaattcg tcttcagtga tttcttttgc
    15361 tttttcttgt ttcttagctt cgtccatagc atcgcgacgg atattgcgga caaccacttt
    15421 agcattttcg ccgaccttct tcacttcttt agcaaggtca cgacgagttt cttctgtaag
    15481 agctgggata accaagcgaa tcacagaacc gtcattagcc ggtgtgatac caagatcaga
    15541 agcgttcaag gcacgttcga tgtctttcaa tgaagacttg tcaaatggtg ttaccaacaa
    15601 aacacgcgct tctggaatcg taattgaagc gatttggtta agaggagttt cgactccata
    15661 gtattctaca tgtacacggt caagcaagct tgcattggca cgaccagcac ggataccacc
    15721 aaattcacga gcaagtgatt ggtgagactg ggtcattctc tctttagctt tttcaataat
    15781 tatgttagcc atattctttc ttattccttt tcttcgatat tatttgaaac tgttgttccg
    15841 atattttcac caaatacgac acgtttgatg ttgcctgatt ggttcatgtt gaagacaacc
    15901 aagtcaatgt cgttgtccat tgagagggtt gaggctgttg agtccatgat acgaagacct
    15961 ttgttgataa catcacggtg ggtcaattct tcaaacttaa cggctgtctt gtccttctta
    16021 ggatcggcat tgtacacacc atcgacgcca tttttagcca tgaggatggc atctgcttcg
    16081 atttcagctg cgcgaagggc cgctgttgta tctgtcgaga agtatggtga accaattcca
    16141 gcaccaaaga taacgatacg gcctttttca aggtgacgaa gggcacgtcc acggacataa
    16201 ggctctgcca cttgttgcat agcaatagct gtttgtacac gcgtatcaac cccaacttgt
    16261 tgcaatgaat ctgccatcac aagagcattc ataacagtcc caagcattcc agtgtaatct
    16321 gcctgaacac ggtccatacc tgcttctgct gcaggttctc cacgccagag atttcctcca
    16381 ccaataacaa gggcaatttc gatacctaag ctatgaactt cttgaatctc ttttgcgatt
    16441 gtttgaactg tttggatatc aatccctacg ccacgttcac cggcaagggc ttcacctgat
    16501 aacttgatta aaatacgttt atacttggga ttcgccattt tcactctcct tctttcatcc
    16561 tacctatttt atcacaattt ctaagatttt tatagtatca tgagcaattc tttcaaaaaa
    16621 attagacagt caaaaattcc tctaagtcgg caagggcacg ctctgcaatt ttttcataac
    16681 gagccttctt atcacggata cgctcgcctt ccaactcctt gatgatccca aaattgacat
    16741 tcattggttg gaaatgtttg ctgtcggcat gggtaatgta atgagctaag cttccaatcg
    16801 ctgtcgtctc ggggaaaata acctcgcttt cttccttgaa gagacgagct gcgttaattc
    16861 ccgcaactaa gcccgaagcc gccgactcaa catagccttc cacccccgtc atctgaccag
    16921 caaagaagag atttggttgt ttcttggaac ggtaagtctg ctcaagaaga tttggtgaat
    16981 ccatgtaaga attgcgatgc atgacaccat aacggacaaa ctccgcattt tcaagacccg
    17041 gaatcatttg gaagacacgc ttttgttctc cccatttgag gtgggtctgg aaaccaacaa
    17101 tattgtatag gctaccagct gcattatcct gacgaagttg cacaaccgca taaggtgttt
    17161 taaattctcc atcacgaggt cctgtgtagt cgtccggata ctcaagaccg actggcttca
    17221 tagggccata aagcatagtt ttaatgccac gtttggccat aacttcgatt ggcatacatc
    17281 cttcaaagta cttttctttt tcaaaagaat tgagcggtgc ttcttccgca ttgaccaagg
    17341 cttcatggaa atccataaac tcttgcttgg tcattggagc attgagatag gctgcttctc
    17401 ccttatcata acgagatttg agatagacct tactcatatc gatagtgttg acatcgataa
    17461 taggcgctgc tgcatcgtag aaatagaagc catcgccatt attaagggca tgaatctttt
    17521 cagccagggc atcgctagtc aagggaccag tcgccacaac tgtaataaca tctgttggca
    17581 attctgtaat ttcatcacgc accacttcaa tcaaggggtg gttgaccact ttttcggtca
    17641 ccatttgaga gaaaccatca cgatccaccg caagggctcc accggcagga acacgggtag
    17701 cctcagcaga ttccaagata acagaaccca agcgacgcat ttcttccttg agaagaccaa
    17761 ctgcatttgt caaagcatcc ccacgcaaag aattggaaca aaccaactca gcaaaattgt
    17821 ctgttttatg ctggggtgta gacttgacac cacgcatttc atatagttta actggaatac
    17881 cacgctctgc gatttggtaa gctgcttcag aacctgccaa accagcaccg ataacattga
    17941 tataagattg agacacgaca ctaatacctc tttgggagtg tgaagttaag attcacattg
    18001 aaaaagccaa tcagacttac aagctttcga gtttcttggc tcaggctgaa aaagtccaca
    18061 gggctttttc actcccacaa atctttctat tttttcttct actagtataa caaaaaaagg
    18121 gaagaaggca aacttccctg tttagtcatt ttcttgatgt aaagagatag tgagtattcc
    18181 agttaagaat caattatatg ctactctata aaatcttttc cacataacgg atcgataggg
    18241 actgttattc tatctcttgc tataaccgta ttatctaaaa cagcataaca ttcaacatag
    18301 tgatctcctt taaactgtga atcttcgtga tattttattt tacctgaaaa aatagcacca
    18361 cgctcacaat ttcttctaat agcctcagct tcaatatttc ttactttcca atagacttcc
    18421 tgcgaaacaa aatatggtat agtagttcta tgaatgatga agcaagtaaa caactaactg
    18481 atgcacgatt taagcgtctt gttggtgttc agcgcacgac ttttgaagag atattagctg
    18541 tattaaaaac agcttatcaa cttaaacacg caaaaggtgg acgaaaacct aaattaagcc
    18601 tagaagacct tcttatggcc actcttcaat atgtgcgaga atatcgaact tatgaacaaa
    18661 ttgcggctga ttttggtatt cacgaaagca acttaatccg tcggagccaa tgggttgaag
    18721 taactcttgt tcaaagtggt gttacgattt caagaactcc tctcagttct gaggacacgg
    18781 taatgattga tgtgacggaa gtaaaaagaa atcccacgct atgaaggctc aggcgattgt
    18841 cacaagtcaa gggagaattg tttctttgga tatcgctgtg aactatagtc atgatatgaa
    18901 gttgttcaaa atgagttgca gaaatatcgg acaagctggt aaaatcttgg ccgacagtgg
    18961 ttatcaaggg ctcatgaaga tatatcctca agcacaaact ccacgtaaat ccagcaaact
    19021 caagccgcta acagctgaag ataaagcctg taaccatgcg ctatctaagg agagaagcaa
    19081 ggttgagaac atctttgcca aagtaaaaac gtttaaaatg ttttcaacaa cctatcgaaa
    19141 tcatcgtaaa cgcttcggat tacgaatgaa tttgattgct ggtattatca atcatgaact
    19201 aggattctag ttttgcagga agtctaatgt aattctcaag ctgtgagttc attatgattt
    19261 gtaaatccga tatatcttca gcagctaaaa acacattttg aaatgttcca agtccgtttt
    19321 caccaaaact atattctctc ttactatact tactcttatt attctctata tagttatagt
    19381 tagagtcaag gttcttaacc tcttgaagtt cattttcttt acttctgagg ttaaaatctt
    19441 ttacttctga agttaagttt tttgacttct gtaagtcatt ttcttttacc tgaaatatac
    19501 tcataaagtc tttaacataa atgatgttcg gcttaccaag tccaagcctt actctttcga
    19561 tcagtcctat tccttttttt acatcaagct catctaatgt ttttatggca gttggctttg
    19621 agatatttct tcttttcata atttcttcga cagtaaaata gataaatact ctgccttcct
    19681 tgtctatcca gttattctta aatgacattc ctgtctgttt aagaagtatg gaataaagga
    19741 taattgcttc tgctgataag ccccgaaatt cttctctatc aactaatatc tccggtactt
    19801 ttaagaagtt aaatctttcc gcttctctgt tataaaaata ttcaaagtcc atgcaagatc
    19861 acctcccttc ttaaaaattt gcaaagaaaa agacgatagt ttttcttcta tcgcctttgg
    19921 taaccatttt tatgaaat
//
LOCUS       DBEJAU010000041        19350 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC323 isolate 683620
            SAMN38261939-rid24807223.denovo.041, whole genome shotgun sequence.
ACCESSION   DBEJAU010000041 DBEJAU010000000
VERSION     DBEJAU010000041.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261939
            Sequence Read Archive: SRR26833919
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 19350)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 19350)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576303.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576303.1
            Genome Coverage       :: 154x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/19/2025 01:05:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,121
            CDSs (total)                      :: 2,078
            Genes (coding)                    :: 1,943
            CDSs (with protein)               :: 1,943
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 36
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 72 of 135
            Pseudo Genes (incomplete)         :: 63 of 135
            Pseudo Genes (internal stop)      :: 51 of 135
            Pseudo Genes (multiple problems)  :: 46 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..19350
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261939-rid24807223.denovo.041"
                     /strain="GPSC323"
                     /isolate="683620"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            complement(115..330)
                     /locus_tag="ACL29Z_001543"
     CDS             complement(115..330)
                     /locus_tag="ACL29Z_001543"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002893653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0069826.1"
                     /translation="MAKSNFEKVESVVGWVRDKKITGYRISKETNAREMSIIALAQGR
                     AKVKNISFETALGLIDFYEKNYEKFED"
     gene            complement(1199..2449)
                     /gene="ilvA"
                     /locus_tag="ACL29Z_001544"
     CDS             complement(1199..2449)
                     /gene="ilvA"
                     /locus_tag="ACL29Z_001544"
                     /EC_number="4.3.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006151817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004794 - threonine deaminase activity
                     [Evidence IEA];
                     GO_process: GO:0006520 - amino acid metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="threonine ammonia-lyase IlvA"
                     /protein_id="HGR0069827.1"
                     /translation="MLSSKDIIKAHKVLNGVVVNTPLDYDHYLSEKYGAKIYLKKENA
                     QRVRSFKIRGAYYAISQLSKEERERGVVCASAGNHAQGVAYTCNEMKIPATIFMPITT
                     PQQKIGQVRFFGGDFVTIKLVGDTFDASAKAAQEFTVSENRTFIDPFDDAHVQAGQGT
                     VAYEILEEARKESIDFDAVLVPVGGGGLIAGVSTYIKETSPEIEVIGVEANGARSMKA
                     AFEAGGPVKLKEIDKFADGIAVQKVGQLTYEATRQHIQTLVGVDEGLISETLIDLYSK
                     QGIVAEPAGAASIASLEVLAEYIKGKTICCIISGGNNDINRMPEMEERALIYDGIKHY
                     FVVNFPQRPGALREFVNDILGPNDDITRFEYIKRASKGTGPVLIGIALADKHDYAGLI
                     RRMEGFDPAYINLNGNETLYNMLV"
     gene            complement(2499..2855)
                     /locus_tag="ACL29Z_001545"
     CDS             complement(2499..2855)
                     /locus_tag="ACL29Z_001545"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001027901.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ketol-acid reductoisomerase"
                     /protein_id="HGR0069828.1"
                     /translation="MNITNLFSIKTGCDETDRQLQKLFFQLDLQLGELTDQLRKLDSN
                     FVPRSQFVDTLDLNDVEYKEILNYFIFHRNDSEESLVEWLYDWISTNRYELPKEFSIH
                     MAHKYHESVTEVFGDE"
     gene            complement(3093..3329)
                     /locus_tag="ACL29Z_001546"
     CDS             complement(3093..3329)
                     /locus_tag="ACL29Z_001546"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001813675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0069829.1"
                     /translation="MLADQNKADWSYDENAVINIYDDANFEYGRLHMNFEQFFKLAQI
                     AREEGLEIHSPFERAGATKSARYIAKWILRNKKH"
     gene            complement(3436..4458)
                     /gene="ilvC"
                     /locus_tag="ACL29Z_001547"
     CDS             complement(3436..4458)
                     /gene="ilvC"
                     /locus_tag="ACL29Z_001547"
                     /EC_number="1.1.1.86"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006145054.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ketol-acid reductoisomerase"
                     /protein_id="HGR0069830.1"
                     /translation="MTVQMEYEKDVKVAALDGKKIAVIGYGSQGHAHAQNLRDSGRDV
                     IIGVRPGKSFDKAKEDGFDTYTVAEATKLADVIMILAPDEIQQELYEAEIAPNLEAGN
                     AVGFAHGFNIHFEFIKVPADVDVFMCAPKGPGHLVRRTYEEGFGVPALYAVYQDATGN
                     AKNIAMDWCKGVGAARVGLLETTYKEETEEDLFGEQAVLCGGLTALIEAGFEVLTEAG
                     YAPELAYFEVLHEMKLIVDLIYEGGFKKMRQSISNTAEYGDYVSGPRVITEQVKENMK
                     AVLADIQNGKFANDFVNDYKAGRPKLTAYREQAANLEIEKVGAELRKAMPFVGKNDDD
                     AFKIYN"
     gene            complement(4524..5000)
                     /gene="ilvN"
                     /locus_tag="ACL29Z_001548"
     CDS             complement(4524..5000)
                     /gene="ilvN"
                     /locus_tag="ACL29Z_001548"
                     /EC_number="2.2.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002927678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:1990610 - acetolactate synthase regulator
                     activity [Evidence IEA];
                     GO_process: GO:0009082 - branched-chain amino acid
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acetolactate synthase small subunit"
                     /protein_id="HGR0069831.1"
                     /translation="MRRMLTAKLQNRSGVLNRFTGVLSRRQVNIESISVGATEDPNVS
                     RITIIIDVASHDEVEQIIKQLNRQIDVIRIRDITDKPHLEREVILVKMSAPAEKRAEI
                     LAIIQPFRATVVDVAPSSITIQMTGNAEKSEALLRVIRPYGIRNIARTGATGFTRD"
     gene            complement(4993..6693)
                     /locus_tag="ACL29Z_001549"
     CDS             complement(4993..6693)
                     /locus_tag="ACL29Z_001549"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000411733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetolactate synthase large subunit"
                     /protein_id="HGR0069832.1"
                     /translation="MEKISLESPKTGSDLVLETLRDLGVDTIFGYPGGAVLPFYDAIY
                     NFKGIRHILGRHEQGCLHEAEGYAKSTGKLGVAVVTSGPGATNAITGIADAMSDSVPL
                     LVFTGQVARAGIGKDAFQEADIVGITMPITKYNYQVRETADIPRIITEAVHIATTGRP
                     GPVVIDLPKDISALETDFIYSPEVNLPSYQPTLEPNDMQIKKILKQLSKAKKPVLLAG
                     GGISYAEAATELNEFAERYQIPVVTSLLGQGTIATSHPLFLGMGGMHGSFAANIAMTE
                     ADFMISIGSRFDDRLTGNPKTFAKNAKVAHIDIDPAEIGKIISADIPVVGDAKKALQM
                     LLAEPTVHNNTEKWIEKVTKDKNRVRSYDKKERVVQPQAVIERIGELTNGDAIVVTDV
                     GQHQMWTAQYYPYQNERQLVTSGGLGTMGFGIPAAIGAKIANPDKEVVLFVGDGGFQM
                     TNQELAILNIYKVPIKVVMLNNHSLGMVRQWQESFYEGRTSESVFDALPDFQLMAQAY
                     GIKNYKFDNPETLAQDLEVITEDVPMLIEVDISRKEQVLPMVPAGKSNHEMLGVQFHA
                     "
     gene            complement(6894..8561)
                     /locus_tag="ACL29Z_001550"
     CDS             complement(6894..8561)
                     /locus_tag="ACL29Z_001550"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000036655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DAK2 domain-containing protein"
                     /protein_id="HGR0069833.1"
                     /translation="MSKITTSLFQEMVQAASTRLNKQAEYVNSLNVFPVPDGDTGTNM
                     GMTIENGAKEVADKPASTVGEVASILAKGLLMGARGNSGVITSQLFRGFSQAIKDKDE
                     LTGQDLALAFQSGVEVAYKAVMKPVEGTILTVSRGAAIGAKKKAEQTDDTVEVMRAAL
                     EGAKTALAKTPDMLPVLKEVGVVDSGGQGLVFIYEGFLSALTGEYIASEDFVATPANM
                     SEMINVEHHKSVAGHVATEDITFGYCTEIMVALKQGPTYAKDFDYDEFRNYLDELGDS
                     LLVVNDDEIVKVHVHTEDPGLVMQEGLKYGSLVKVKVDNMRNQHEAQVEKEATQVIKS
                     AEEKEYALIAVVAGKGLADIFCSQGVDYVIEGGQTMNPSTEDFIKAVEQVNARNIIFL
                     PNNKNIFMAAQSAAEVLEQPAVVVEARTLPQGMTSLLAFDPSKSIEENQERMTAALSD
                     VVSGSVTTAVRDTTIDGLEIHENDNLGMVDGKILVSNPDMHQTLTETLKHMLDEDSEI
                     VTFYVGEDGSEELANEIAQEIVEEFEDVEVEIHQGQQPVYPYLFSVE"
     gene            complement(8564..8929)
                     /locus_tag="ACL29Z_001551"
     CDS             complement(8564..8929)
                     /locus_tag="ACL29Z_001551"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018371966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HGR0069834.1"
                     /translation="MTVKINTKDGQIELTDEVIATVVGGAATEIFGVVGMASKNALKD
                     NFQALLGKENYSKGVVVKAAEDGSIAVDVYTVLSYGTKISEVSKNIQERVAFSLENQL
                     GITAQTVNVYIQNIKVVGE"
     gene            complement(9086..9274)
                     /gene="rpmB"
                     /locus_tag="ACL29Z_001552"
     CDS             complement(9086..9274)
                     /gene="rpmB"
                     /locus_tag="ACL29Z_001552"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008536053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L28"
                     /protein_id="HGR0069835.1"
                     /translation="MAKVCYFTGRKTVSGNNRSHAMNQTKRAVKPNLQKVTVLIDGKP
                     KKVWASARALKSGKVERV"
     gene            complement(9390..9566)
                     /locus_tag="ACL29Z_001553"
     CDS             complement(9390..9566)
                     /locus_tag="ACL29Z_001553"
                     /inference="COORDINATES: protein motif:HMM:NF013652.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016757 - glycosyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HGR0069836.1"
                     /translation="MDSDIVVRKSIDELWDLDLTAIPLAAVRDDFYTHNFNSGVLLIN
                     NGMWRAENVTQDLI"
     gene            complement(9677..9874)
                     /locus_tag="ACL29Z_001554"
     CDS             complement(9677..9874)
                     /locus_tag="ACL29Z_001554"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0069837.1"
                     /translation="MKEEKKAIVLGADNAYMDKVETTIKSLCIHHYNLKFYVFNDDLP
                     REWFQLMEKRLETLNSEIVNV"
     gene            complement(10302..11846)
                     /locus_tag="ACL29Z_001555"
     CDS             complement(10302..11846)
                     /locus_tag="ACL29Z_001555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011681503.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_process: GO:0006415 - translational termination
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 3"
                     /protein_id="HGR0069838.1"
                     /translation="MNIQEEIKKRRTFAIISHPDAGKTTITEQLLYFGGEIREAGTVK
                     GKKTGTFAKSDWMDIEKQRGISVTSSVMQFDYDGKRVNILDTPGHEDFSEDTYRTLMA
                     VDAAVMVVDSAKGIEAQTKKLFEVVKHRGIPVFTFMNKLDRDGREPLDLLQELEEILG
                     IASYPMNWPIGMGKAFEGLYDLYNQRLELYKGDERFASLEDGDKLFGSNPFYEQVKDD
                     IELLNEAGNEFSEEAILAGELTPVFFGSALTNFGVQTFLETFLKFAPEPHGHKKTDGE
                     IVDPYDKDFSGFVFKIQANMDPRHRDRIAFVRIVSGEFERGMSVNFPRTGKGAKLSNV
                     TQFMAESRENVTNAVAGDIIGVYDTGTYQVGDTLTVGKNKFEFEPLPTFTPEIFMKVS
                     AKNVMKQKSFHKGIEQLVQEGAVQLYKNYQTGEYMLGAVGQLQFEVFKHRMEGEYNAE
                     VVMNPMGKKTVRWIKPEDLDERMSSSRNILAKDRFDQPVFLFENDFALRWFADKYPDV
                     ELEEKM"
     gene            12059..12361
                     /gene="gatC"
                     /locus_tag="ACL29Z_001556"
     CDS             12059..12361
                     /gene="gatC"
                     /locus_tag="ACL29Z_001556"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006147946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0030956 - glutamyl-tRNA(Gln)
                     amidotransferase complex [Evidence IEA];
                     GO_function: GO:0050567 - glutaminyl-tRNA synthase
                     (glutamine-hydrolyzing) activity [Evidence IEA];
                     GO_process: GO:0006424 - glutamyl-tRNA aminoacylation
                     [Evidence IEA];
                     GO_process: GO:0006450 - regulation of translational
                     fidelity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatC"
                     /protein_id="HGR0069839.1"
                     /translation="MKITQEEVTHVANLSKLRFSEEETAAFATTLSKIVDMVELLGEV
                     DTTGVAPTTTMADRKTVLRPDVVEEGTDRDRLFKNVPEKDNYYIKVPAILDDGGDA"
     gene            12361..13827
                     /gene="gatA"
                     /locus_tag="ACL29Z_001557"
     CDS             12361..13827
                     /gene="gatA"
                     /locus_tag="ACL29Z_001557"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0030956 - glutamyl-tRNA(Gln)
                     amidotransferase complex [Evidence IEA];
                     GO_function: GO:0050567 - glutaminyl-tRNA synthase
                     (glutamine-hydrolyzing) activity [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA];
                     GO_process: GO:0006424 - glutamyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatA"
                     /protein_id="HGR0069840.1"
                     /translation="MTFNNKTIEELHNLLVSKEISATELTQATLENIKSREEALNSFV
                     TIAEEQALVQAKAIDEAGIDADNVLSGIPLAVKDNISTDGILTTAASKMLYNYEPIFD
                     ATAVANAKTKGMIVVGKTNMDEFAMGGSGETSHYGATKNAWDHSKVPGGSSSGSAAAV
                     ASGQVRLSLGSDTGGSIRQPAAFNGIVGLKPTYGTVSRFGLIAFGSSLDQIGPFAPTV
                     KENALLLNAIASEDAKDSTSAPVRIADFTSKIGQDIKGMKIALPKEYLGEGINPEVKE
                     TILNAAKHFEKLGAIVEEVSLPHSKYGVAVYYIIASSEASSNLQRFDGIRYGYRAEDA
                     TNLDEIYVNSRSQGFGEEVKRRIMLGTFSLSSGYYDAYYKKAGQVRTLIIQDFEKVFA
                     DYDLILGPTAPSVAYDLDSLNHDPVAMYLADLLTIPVNLAGLPGISIPAGFSQGLPVG
                     LQLIGPKYSEETIYQAAAAFEATTDYHKQQPVIFGGDN"
     gene            13827..15269
                     /gene="gatB"
                     /locus_tag="ACL29Z_001558"
     CDS             13827..15269
                     /gene="gatB"
                     /locus_tag="ACL29Z_001558"
                     /EC_number="6.3.5.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002946582.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016884 - carbon-nitrogen ligase activity,
                     with glutamine as amido-N-donor [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatB"
                     /protein_id="HGR0069841.1"
                     /translation="MNFETVIGLEVHVELNTNSKIFSPTSAHFGNDQNANTNVIDWSF
                     PGVLPVLNKGVVDAGIKAALALNMDIHKKMHFDRKNYFYPDNPKAYQISQFDEPIGYN
                     GWIEVELEDGTTKKIGIERAHLEEDAGKNTHGTDGYSYVDLNRQGVPLIEIVSEADMR
                     SPEEAYAYLTALKEVIQYAGISDVKMEEGSMRVDANISLRPYGQEKFGTKTELKNLNS
                     FSNVRKGLEYEVQRQAEILRSGGQIRQETRRYDEANKATILMRVKEGAADYRYFPEPD
                     LPLFEISDEWIEEMRTELPEFPKERRARYVSDLGLSDYDASQLTANKVTSDFFEKAVA
                     LGGDAKQVSNWLQGEVAQFLNAEGKTLEQIELTPENLVEMIAIIEDGTISSKIAKKVF
                     VHLAKNGGGAREYVEKAGMVQISDPAILIPIIHQVFADNEAAVADFKSGKRNADKAFT
                     GFLMKATKGQANPQVALKLLAQELAKLKEN"
     gene            15393..16436
                     /locus_tag="ACL29Z_001559"
     CDS             15393..16436
                     /locus_tag="ACL29Z_001559"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000224421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2,3-butanediol dehydrogenase"
                     /protein_id="HGR0069842.1"
                     /translation="MATMKAARWHAAKDVRIQEIEVPEVLPHQVKVAVKFTGICGTDL
                     HEFLDGPIFIPTDEHVYSGQKAPVTLGHEFSGEIIEVGSDVTRVKVGDRVAVEPILAK
                     NNLVGDYNLDPNLNFVGLAADGGFAKYCVLDGDLVHVIPDSLSYEQAALTEPAAVAVY
                     AVRQSSLKAGDTAVVFGLGPIGLLIVEALRAAGASKIYAVELSPERQAKAEELGAIVV
                     RPEEGETAVEAIHRLTNGGVDVSYEVTGVPVVLGQALAAVHKAGECMVVSIWEREANI
                     NPNEFAIQEKTLKGIIAYRHIFPKVLELMEQGYFSAEKLVTKKIKLENIVEEGFIELT
                     QDKSQIKILVEPE"
     gene            complement(16461..16691)
                     /locus_tag="ACL29Z_001560"
     CDS             complement(16461..16691)
                     /locus_tag="ACL29Z_001560"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0069843.1"
                     /translation="MVNVKEYPLYFFSYSMEIKEQTRKLAAGCSKHCFEVVDRTDEVS
                     NHIYGNVTLTWFEEIFEEYYISKGRSKFTPTC"
     gene            16814..17374
                     /gene="efp"
                     /locus_tag="ACL29Z_001561"
     CDS             16814..17374
                     /gene="efp"
                     /locus_tag="ACL29Z_001561"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000568636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0003746 - translation elongation factor
                     activity [Evidence IEA];
                     GO_process: GO:0006414 - translational elongation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor P"
                     /protein_id="HGR0069844.1"
                     /translation="MIEASKLKAGMTFETADGKLIRVLEASHHKPGKGNTIMRMKLRD
                     VRTGSTFDTSYRPEEKFEQAIIETVPAQYLYKMDDTAYFMNTETYDQYEIPVVNVENE
                     LLYILENSDVKIQFYGTEVIGVTVPTTVELTVAETQPSIKGATVTGSGKPATMETGLV
                     VNVPDFIEAGQKLVINTAEGTYVSRA"
     gene            17396..17785
                     /locus_tag="ACL29Z_001562"
     CDS             17396..17785
                     /locus_tag="ACL29Z_001562"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517858.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HGR0069845.1"
                     /translation="MGIEEQLGEIVIAPRVLEKIIAIATAKVEGVHSFSNRSVSDTLS
                     KLSLGRGIYLKNVDEELTADIYLYLEYGVKVPKVAVAIQKAVKDAVRNMADVELAAIN
                     IHVAGIVPDKTPKPELKDLFDEDFLND"
     gene            17778..18200
                     /gene="nusB"
                     /locus_tag="ACL29Z_001563"
     CDS             17778..18200
                     /gene="nusB"
                     /locus_tag="ACL29Z_001563"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000203663.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_process: GO:0006353 - DNA-templated transcription
                     termination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antitermination factor NusB"
                     /protein_id="HGR0069846.1"
                     /translation="MTSPLLESRRQLRKCAFQALMSLEFGTDVETACRFAYTHDREYT
                     DVQLPAFLIDLVSGVQAKKEELDKQITQHLKAGWTIERLTLVERNLLRLGVFEITSFD
                     TPQLVAVNEAIELAKDFSDQKSARFINGLLSQFVTEEQ"
     gene            complement(18235..19350)
                     /locus_tag="ACL29Z_001564"
                     /pseudo
     CDS             complement(18235..19350)
                     /locus_tag="ACL29Z_001564"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014632353.1"
                     /note="frameshifted; incomplete; missing N-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=3
                     /transl_table=11
                     /product="transposase"
BASE COUNT         5678 a         4286 c         3578 g         5808 t
ORIGIN      
        1 aaataaaaag aaaaggctgc atcaaccgtg cagtcttttt gctgtcctca aaatgaaaag
       61 gcagattctc tatctctact acttgaaggt caagaatccg ctgttatcca aagattaatc
      121 ttcaaatttt tcataatttt tttcatagaa atcaattagg cctagggctg tttcaaatga
      181 aatatttttt acttttgcac gaccctgcgc cagagcaatg atagacattt cacgcgcatt
      241 cgtttcttta gagatacggt agcctgtgat tttcttatca cgaacccagc caacaactga
      301 ttctactttt tcaaagtttg acttagccat gtttttctcc tattttcttc tttataatat
      361 ttaattgtat acgtttttac tacttttgtc aataaaaaaa acatatattc aacgaaaata
      421 attagttcaa aattttctta cttccttttt aaatccgata atatataggt tttgctagcc
      481 tctacaccat aaatatttgc taataaaaat actgtattat taccctctta aggtgcgaaa
      541 ttattcaagt tcttaaaaaa tgcttctcta tttccgtaag atagcttatt tcttcgattt
      601 aagaactgaa gatgatagtt ctaaccttta gaaatccaag ccttcactaa ctcaaaaact
      661 cctatctttc ttcctcaata aatcatctga gagataggta ttccttatat ccttcaaatt
      721 catcactcct ttggatattg aggtgctagc ctagaagcag actcccgatt atctaaacca
      781 tccttaataa agatgacaag acagataagc tcagttaatt acttatatat ctttttaata
      841 tggtatattt gtcaacaaaa aaatcaaatc ataccttata ctcaatgaaa atcaaagagc
      901 aaactaggaa gctagccgca agttgctcaa aacactgttt tgaggttgca gatagagcta
      961 acgtggtttg aagagatttt cgaagagtat taaagacagt gtgactatgc ttgtcaatag
     1021 ataggaaatc aaaatgaagg atggaaatct gagccaaaca tcataagtgc tataatgaac
     1081 agaagtaaga attgcacgat aagtttccta aaaccatagg aatcgtcccc tttcttcatc
     1141 ttcattatag cacatataca tcagttgtac aaataatatt atattttttt attagtcctc
     1201 agacaagcat attataaagc gtttcattac catttaagtt aatataagct ggatcaaaac
     1261 cttccattct acggatcaaa cctgcataat catgcttatc tgctaaagcg atcccaatta
     1321 atactgggcc tgttcccttg ctagctcgtt tgatatactc aaaacgtgtg atatcatcat
     1381 ttggccccag gatatcattt acaaactcac gcaaagctcc tggacgttgt gggaaattga
     1441 ccacaaagta atgtttgata ccatcataaa tcaaggcacg ctcttccatt tctggcatac
     1501 ggttgatatc attatttcct ccagaaatga tacaacaaat ggttttcccc ttaatatatt
     1561 cagctaaaac ctctaaagag gcgatactag ccgctccagc aggttctgcg actatccctt
     1621 gcttagagta aaggtcaatc aaggtttcag aaatcaatcc ctcatcgaca cctaccaaag
     1681 tttgaatatg ttgacgagtt gcttcatagg tcaactgacc taccttttgc acagcaatcc
     1741 catccgcaaa tttatcaatt tccttgagtt tgactggacc tccagcctca aaggcagctt
     1801 tcatggaacg cgctccattc gcctctactc cgataacctc aatctctgga cttgtttcct
     1861 tgatataggt agaaaccccg gcaatgagac cgccaccacc aacaggaacc aagacagcat
     1921 caaaatcaat cgattctttt cgagcttctt ctaaaatctc ataagcaact gttccttgac
     1981 ctgcttgaac atgagcatca tcaaaaggat caataaaggt acgattttca gagactgtaa
     2041 attcttgagc tgctttggct gaggcatcaa aggtatctcc aactagttta atagttacaa
     2101 aatccccacc aaaaaagcga acctgaccaa tcttttgttg tggcgtagta ataggcataa
     2161 agatagtagc aggaattttc atttcattac aagtataggc tactccctgc gcatgatttc
     2221 ccgcagaagc gcagactacc ccacgttcac gttcttcctt gctgagctgg gaaatggcat
     2281 aataggcacc acgaatttta aaggagcgaa cacgctgggc attttctttt ttcaaataaa
     2341 tcttagcacc atacttctcc gataaataat gatcgtaatc cagtggagta ttcacaacca
     2401 caccgttcaa gaccttgtga gccttgatta tatcttttga acttaacata taaaacctct
     2461 ttttctataa aaaacagtca ctaatgactg ttttttagtt attcatctcc aaaaacttca
     2521 gtaacacttt catggtattt atgagccata tgaatcgaaa actctttagg aagttcataa
     2581 cgatttgtgg aaatccaatc atataaccat tctaccaaac tttcttcact atcattacga
     2641 tggaagataa aatagtttaa aatttcttta tattctacat cattcaaatc caacgtgtct
     2701 acaaattgac tacgaggaac aaaattagaa tctaattttc ttagttgatc tgtcaattct
     2761 cccaattgta aatccaactg aaaaaatagt ttttgcagtt gcctatcagt ttcatcacat
     2821 cctgtcttga tagaaaacaa attggtaata ttcatatgat ttcaacccct aaataagtac
     2881 atctaatatc ccacgaatag ctgaagctaa agttttcgca gtccagtcat ttaaacccga
     2941 ttctttcaat ccagatgcaa taatttgctc tatttgatat aaaccgccat ctatcgtctc
     3001 atttattctg cgaagaggac cttcaatata ggataaagct tctccgaatc taacagctga
     3061 tttaggtcct aatgatttac caactatatt tgttaatgtt ttttatttct caaaatccat
     3121 ttcgctatat aacgagcaga tttagtcgca ccagctctct caaacggaga atgaatttca
     3181 agaccttctt ctctagctat ttgtgccaat ttgaagaatt gttcaaagtt catatgcaac
     3241 ctaccatatt caaaattagc atcatcataa atgttaatta cagcattttc atcatacgac
     3301 caatctgctt tattttggtc tgctagcact attaccgacg gtgtaattac attatacaac
     3361 tagaaccaat aataacgatg caatttttct cataatcttt ttcataaaat catctccagc
     3421 gctatatatt tctaattagt tatagatttt gaatgcatca tcgtcgtttt taccaacgaa
     3481 tggcattgct ttacgcaatt ctgcaccaac tttttcaatt tcaaggttag ctgcttgttc
     3541 acggtaagca gtcaattttg gacgtccagc tttatagtca tttacaaagt catttgcaaa
     3601 tttaccattt tggatgtctg ccaagacagc cttcatattt tctttaactt gttcagtgat
     3661 tacacgtgga cctgatacat agtcaccgta ttcagcagtg tttgaaatag attgacgcat
     3721 tttcttgaat ccaccttcgt agatcaagtc aacgatcaat ttcatttcgt gaagaacttc
     3781 aaagtaagcc aattctggag cgtaacctgc ttctgtcaag acttcgaaac ctgcttcgat
     3841 aagggcagtc aaaccaccac aaagtacagc ttgttcacca aacaaatctt cttcagtttc
     3901 ttctttgtaa gttgtttcaa gaagacctac acgagccgct ccaacacctt tacaccagtc
     3961 catagcaatg tttttagcat ttcctgttgc atcttggtat actgcataaa gagctggaac
     4021 accaaatcct tcttcgtaag tacgacgtac caagtgtcct ggtcctttag gagcacacat
     4081 gaagacatct acatccgcag gaactttgat aaattcaaag tggatgttga aaccatgggc
     4141 aaatccaact gcgtttccag cttccaagtt tggagcgatt tctgcttcgt acaattcttg
     4201 ttgaatttcg tctggcgcca agatcatgat aacatcagcc aacttagtag cttctgctac
     4261 tgtgtaagta tcaaatccat cttcttttgc tttatcaaaa gatttacctg gacgtacacc
     4321 gataataacg tcacgacctg aatcacgcaa gttttgagca tgcgcatgcc cttgtgaacc
     4381 ataaccgata acggcgattt ttttaccgtc aagtgctgct actttaacat ctttttcata
     4441 ttccatttga actgtcatag cttttctctc ttttctatta tttattgcct tttaagctgg
     4501 tttaacaaat ttaagttgga tttttaatcg cgggtaaatc cagttgcacc cgttcgagca
     4561 atattgcgaa taccgtatgg gcgaatgact cgcaataggg cttcgctctt ttctgcattt
     4621 cccgtcatct gaatggtaat cgagcttggc gctacgtcta ccactgttgc acggaaaggt
     4681 tgaataatcg ctaaaatctc agctctcttc tcagctggcg ctgacatctt aaccaaaatc
     4741 acctcgcgct ccaaatgagg cttgtctgta atatctcgaa tgcgaatcac atcaatctga
     4801 cgattgagct gtttgatgat ttgctccact tcatcatgag aagcaacatc aataataata
     4861 gtgatacgcg atacattcgg atcttctgtt gctccaacag agatgctttc aatattaacc
     4921 tgacgacgag ataggacacc tgtaaagcga ttgaggactc ctgaacgatt ttgtagtttt
     4981 gctgttaaca ttctacgcat ggaactgcac ccccaacatc tcatgattac tcttaccagc
     5041 cggtaccatt ggtaacacct gttccttacg agaaatatct acctcaatta gcataggaac
     5101 atcctcagtg atgacttcaa ggtcttgagc caaggtctca ggattgtcaa acttatagtt
     5161 tttaatacca taagcctgcg ccatcaattg gaaatcagga agggcatcaa agaccgactc
     5221 tgatgttctg ccttcataga aggattcctg ccactggcga accattccaa gtgaatgatt
     5281 gttcagcata accaccttga ttggcacctt gtaaatattc aaaatagcca actcctggtt
     5341 ggtcatttgg aaaccaccat ccccaacaaa caagactact tccttatctg ggttagcaat
     5401 tttagcaccg attgctgctg gaattccaaa gcccattgtt cccaaaccac ctgaagtcac
     5461 taactgacgc tcattttggt agggataata ctgagctgtc cacatttggt gttgaccaac
     5521 gtctgttacc acaatggcat ctccattcgt caattcacca attcgttcaa taactgcttg
     5581 cggttgaacc acacgctctt tcttgtcata agaacgaaca cgattcttgt ctttagtgac
     5641 tttctcaatc cacttttcag tattgttgtg aactgttggt tctgctagca acatttgcaa
     5701 ggccttctta gcatctccaa ctacaggaat gtctgcactg ataatcttgc caatctcagc
     5761 tgggtcaata tcaatgtggg caaccttagc attcttagcg aaagtcttag gattccccgt
     5821 caaacggtca tcgaaacgag aaccaatact aatcataaag tccgcttccg tcatggcaat
     5881 atttgctgcg aatgacccgt gcatgcctcc cattccaaga aagagtgggt gactcgttgc
     5941 aatcgttcct tgtcccaaaa gactggttac cactggaatt tgatagcgtt ctgcaaattc
     6001 atttagttcc gtagcagcct cagcataact aattccacca ccagctaaca agactggctt
     6061 tttagccttg gacaattgct tcaagatttt cttgatttgc atatcattcg gctcaagagt
     6121 cggctgataa cttggtaaat tcacttctgg tgaataaatg aagtctgttt ctaaagcaga
     6181 tatgtctttt ggtaggtcaa ttacaactgg ccctggacgg cctgtagttg cgatatggac
     6241 agcttccgta atgatacgcg gaatatcagc tgtctcacga acttggtaat tgtacttagt
     6301 gattggcatg gtaattccca cgatgtctgc ctcctgaaag gcatccttcc caatccctgc
     6361 tcgcgccacc tgacctgtaa agaccaaaag gggaacgcta tcgctcatgg catccgcaat
     6421 ccctgtaatg gcatttgttg ctcctggtcc actagtaacg acggcaacac ccaactttcc
     6481 agttgatttg gcataacctt cagcttcatg caaacaacct tgctcatggc gccctagaat
     6541 gtggcgaatg cctttaaaat tatatatcgc atcataaaaa ggcaaaaccg caccaccagg
     6601 ataaccaaag atggtatcaa ctcctaaatc acgaagtgtt tccaaaacta ggtccgaccc
     6661 cgtcttagga gattctaaac tgattttctc cattgttccc ctttctttcc tcttaaaaat
     6721 aacttgttac tatcatacca ttttttcaaa atttttcaag acaaaagaag aaattttctg
     6781 aattttctat tttaacgttt atttatgaat gttatttttg tttttattaa aaagataccg
     6841 atttcattta ctaaaaaaga aaaaagaact gatttctcag tccttcatta atcttattcc
     6901 acactaaata ggtatgggta aacaggttgt tgaccttggt gaatctcgac ttcaacgtct
     6961 tcgaattctt ctacgatttc ttgagcgatt tcattggcaa gttcttcgct tccgtcttca
     7021 ccgacataga aggttacgat ttcactgtct tcatccaaca tatgtttcaa ggtttcagtc
     7081 aatgtttggt gcatatcagg gtttgacaca agaatttttc catccaccat acctagatta
     7141 tcgttttcat ggatttctaa gccatcgatc gttgtatcac gcacggctgt tgtgacgctt
     7201 ccgctaacga catcgctaag agcagctgtc atacgctctt ggttttcttc aatggacttg
     7261 cttggatcaa aggcaagaag acttgtcata ccttgaggaa gagtgcgagc ctctaccact
     7321 actgctggtt gctccaaaac ttctgccgca gattgagctg ccatgaagat gttcttgttg
     7381 tttggcaaga agatgatgtt acgggcattg acctgttcaa cagccttgat aaagtcttct
     7441 gttgaagggt tcatggtttg accgccttcg ataacataat ccacgccttg agaacagaag
     7501 atatctgcta gacctttacc agctaccaca gcaatcaaag catactcttt ttcttcagcc
     7561 gacttgataa cttgagtagc ttctttctca acctgtgctt cgtgttggtt acgcatattg
     7621 tcaactttta ccttgaccaa gctaccatat ttgagacctt cttgcataac aagtcctgga
     7681 tcttctgtat gaacatggac tttgacaatt tcatcatcgt taacaacgag gagagaatcc
     7741 ccaagctcat ccaagtagtt acggaattca tcgtagtcaa aatctttagc ataggttgga
     7801 ccttgcttaa gagctaccat gatttcagta cagtaaccaa acgtgatgtc ctcagtcgct
     7861 acgtgaccag ctacagactt atgatgctct acattgatca tctcactcat gttggcagga
     7921 gtcgctacaa agtcctcaga tgcaatatat tcgccagtaa gggctgaaag gaaaccttcg
     7981 tagatgaaga ccaatccttg accacctgag tccacaacgc caacttcttt caatactgga
     8041 agcatgtctg gtgttttagc tagagctgtt ttagcacctt ccaaggctgc gcgcatgact
     8101 tcaacagtat catctgtttg ctcagctttt ttcttagcac cgatagcagc tccacgagaa
     8161 actgtcaaaa tcgttccttc aacaggtttc atcactgcct tataggcaac ttccacacct
     8221 gattggaagg ccagggccaa gtcttgacct gttaactcgt ctttatcctt gatagcttgg
     8281 gaaaatccac ggaaaagctg agacgtaatc actcctgagt tcccacgcgc acccatcaaa
     8341 agccctttgg caagaatgct cgctacttct ccaactgtag aagctggctt gtctgcaact
     8401 tctttagcac cattttcaat ggtcattccc atatttgtcc cagtatctcc atctggaact
     8461 ggaaagacgt ttaatgaatt gacatattca gcttgcttat tcaagcgagt tgatgcagcc
     8521 tgcaccattt cttgaaataa gctagtagta atttttgaca cggttattct cctacaactt
     8581 tgatattttg aatgtagaca tttacagtct gagcagtaat tccaagctgg ttttccaagc
     8641 taaaggcaac acgctcttga atgttttttg acacttcact aatctttgtt ccgtagctta
     8701 acacggtata tacatcaact gcaatactgc catcttcggc tgcctttacg acgacacctt
     8761 tagaataatt ttccttacct agcagggctt ggaaattatc tttgagggca tttttactag
     8821 ccataccgac cacaccaaaa atctcagttg ctgctccacc tacgacggtt gcaatcactt
     8881 catctgttag ttcgatttga ccatcttttg tattaatttt tacagtcatc ctttttacct
     8941 caactagttg atactctatt ttatcatatt tcagcccaag tgtaaaagca gaatgatgta
     9001 tcagcggata tttactctat ttttcaaacg atgttatacc cacaataaaa gaaaaaagac
     9061 cctaaggtct cctttgcttt tattattaaa cgcgttcaac tttacctgat ttcaaagcac
     9121 gagctgaagc ccaaactttt ttaggtttac catcgataag aacagtaact ttttgaaggt
     9181 ttggttttac ggcacgtttt gtttggttca tcgcgtgtga acggttgttt cctgatacag
     9241 tcttacgacc tgtaaagtaa catactttag ccattgtgtt ttcctcctat tagatctaat
     9301 atagcggatg tgctagcacc acataccgta ctatgttatc acactttctt gttttttgca
     9361 agggaattgg aagatttttt atttgtgtct taaatcaggt cttgcgtgac attttctgct
     9421 ctccacatgc cattgttgat taacagaaca ccagaattaa aattatgtgt ataaaaatca
     9481 tctctaactg cagctaaggg tatagccgtc aagtccaaat cccacagctc atctatcgat
     9541 tttcttacaa caatatctga atccaaatac agtacacgag actcgcttac atactttgga
     9601 ataaaatacc taaaaaagcc gcatatgaaa gtccctcaaa ggggagacga taacctttca
     9661 gaatactact gtcaatctaa acattcacaa tctcactatt caaagtctct aatctttttt
     9721 ccatcaattg gaaccattct cgcggaaggt catcattaaa aacataaaac ttaagattat
     9781 aatgatgaat acaaagagat tttattgttg tttcaacttt atccatataa gcattatctg
     9841 cacctaagac aatcgctttt ttctcttctt tcactcttta tcttatttct ttttattccc
     9901 atcatatgtt tctacgtaac cattattttc gcctattcgt tcgtaaaacc ataccagtgg
     9961 agattttaga tgaagtccca ttacggttta caatttttac attacgacac ggagttttac
    10021 aaatcgattt catttgccaa acgtagttag taaggcattt agctaggcta cctactttct
    10081 gctacgacgg aaaaatccac aaatcaatac cattcgtgga tttttcctag tgaagcggtt
    10141 aggtaagccg ccatagcggt taccgattat tagattacga cacggagttt ggcaaatcga
    10201 ttctatttgc caaacgtagt tagtgaggca gttagctagt tcgccaaata gcgactagcg
    10261 tccaacaatt tggaacttta gttccaattg ttggtactga gtcacatctt ctcctctaac
    10321 tctacgtctg gatacttgtc cgcaaaccag cggagggcaa agtcattttc aaagagaaag
    10381 actggttggt caaaacggtc tttggctaag atattgcgac ttgacgacat ccgttcatcc
    10441 aagtcctcag gcttgatcca acgaacggtc tttttaccca ttgggttcat aactacttcc
    10501 gcattgtact cgccttccat gcggtgttta aagacttcaa actggagttg acctacagcg
    10561 cctagcatgt actcacctgt ttggtaattc ttataaagct gaacggctcc ttcttgcacc
    10621 aattgctcaa tccccttgtg gaaagatttt tgcttcataa cattcttagc agaaactttc
    10681 atgaaaattt caggagtaaa agttggcagt ggttcaaatt caaacttgtt tttaccaact
    10741 gtcaaggtat ccccaacttg ataagtacct gtatcgtaaa ccccgataat atcacctgcc
    10801 acggcattgg tcacattctc acgactttcc gccataaact gagtaacatt agacagttta
    10861 gcccccttac cagtacgagg gaaattaaca ctcatgccgc gctcaaattc gccagatacg
    10921 atacggacaa aggcaatacg gtcacggtga cgagggtcca tgttggcttg gattttaaag
    10981 acaaagcctg agaaatcctt gtcataagga tccacaattt caccgtctgt tttcttgtga
    11041 ccatgtggtt ctggagcaaa cttgaggaag gtttcaagga aggtctgcac accaaagttt
    11101 gtcagggctg aaccgaaaaa gacaggcgtc aattctccag ccagaatagc ttcctctgaa
    11161 aactcattcc cagcttcatt taaaagctca atgtcatcct tgacttgctc gtaaaaagga
    11221 ttgctaccaa aaagtttgtc cccatcttct aggctagcaa aacgctcatc ccctttataa
    11281 agttctaaac gttggttata gaggtcatac aagccctcaa aggctttccc catcccgata
    11341 ggccagttca tagggtagct agcaatgccc aagatttctt ccaattcttg caagagatcc
    11401 aaaggctcac gaccgtcacg gtccagcttg ttcataaagg taaaaactgg aatgccacga
    11461 tgtttcacaa cctcaaacaa tttcttggtt tgagcctcga tccccttggc agagtccacg
    11521 accatgaccg cagcatccac cgccatcaag gtacgatagg tatcttctga gaagtcctcg
    11581 tgccctggcg tgtctaagat attcacgcgc ttgccgtcgt agtcaaattg cataacagat
    11641 gaagtaacag aaatcccacg ttgcttctcg atatccatcc agtcagattt agcaaaagtc
    11701 cctgttttct tcccttttac cgtaccagcc tcacgaatct cacccccaaa gtagagtaac
    11761 tgctcagtga tggttgtttt tcccgcgtcc gggtgggaga taatggcaaa ggtacgacgt
    11821 ttcttaattt cttcttgaat attcataagt tctctttctt tgattctcta tttttcttgt
    11881 ttcaatagct gagaatgatt tttacattgg attttaccat tcctttcaac actccattat
    11941 atcggatttt agcatttttt tcaatttcta tttcttttca cttccccctc ccttatttat
    12001 aggaaaatat ggtaaaatag aacagactaa aaatcatcat ttcacgaaag gatgcaagat
    12061 gaaaattacg caagaagagg taacacacgt tgccaatctt tcaaaattaa gattctctga
    12121 agaagaaact gctgcctttg cgaccacctt gtctaagatt gttgacatgg ttgaattgct
    12181 gggcgaagtt gacacaactg gtgtcgcacc tactacgact atggctgacc gcaagactgt
    12241 actccgccct gatgtggtcg aagaaggaac agaccgtgat cgcttgttta aaaacgtacc
    12301 tgaaaaagac aactactata tcaaggtgcc agctatccta gacgatggag gagatgccta
    12361 atgactttta acaataaaac tattgaagag ttgcacaatc tccttgtctc taaggaaatt
    12421 tctgcaacag aattgaccca agcaacactt gaaaatatca agtctcgtga ggaagccctc
    12481 aattcatttg tcaccatcgc tgaggagcaa gctcttgttc aagctaaagc cattgatgaa
    12541 gctggaattg atgctgacaa tgtcctttca ggaattccac ttgctgttaa ggataacatc
    12601 tctacagacg gtattctcac aactgctgcc tcaaaaatgc tctacaacta tgagccaatc
    12661 tttgatgcga cagctgttgc caatgcaaaa accaagggca tgattgtcgt tggaaagacc
    12721 aacatggacg aatttgctat gggtggttca ggtgaaactt cacactacgg agcaactaaa
    12781 aacgcttggg accacagcaa ggttcctggt gggtcatcaa gtggttctgc cgcagctgta
    12841 gcctcaggac aagttcgctt gtcacttggt tctgatactg gtggttccat ccgccaacct
    12901 gctgccttca acggaatcgt tggtctcaaa ccaacctacg gaacagtttc acgtttcggt
    12961 ctcattgcct ttggtagctc attagaccag attggacctt ttgctcctac tgttaaggaa
    13021 aatgccctct tgctcaacgc tattgccagc gaagatgcta aagactctac ttctgctcct
    13081 gtccgcatcg ccgactttac ttcaaaaatc ggccaagaca tcaagggtat gaaaatcgct
    13141 ttgcctaagg aatacctcgg tgaaggaatt aacccagagg ttaaggaaac cattctaaat
    13201 gccgctaaac actttgaaaa attgggtgct attgtcgaag aagtcagcct tcctcactct
    13261 aaatacggag ttgccgtata ctacatcatc gcttcatcag aagcttcatc aaacttgcaa
    13321 cgttttgacg gtatccgtta cggctaccgc gcagaagatg caaccaacct tgatgaaatc
    13381 tatgtaaaca gccgaagcca aggttttggt gaagaggtaa aacgtcgtat catgctgggt
    13441 actttcagtc tttcatcagg ttactatgat gcctactaca aaaaggctgg tcaagtccgt
    13501 accctcatca ttcaagattt cgaaaaagtc ttcgcagatt acgatttgat tttgggtcca
    13561 actgctccaa gtgttgccta tgacttggac tcactcaacc atgacccagt tgccatgtac
    13621 ttggctgacc tcttgaccat acctgtaaac ttagcaggtc tccctggaat ttcgattcct
    13681 gctggattct ctcaaggtct acctgtcggt ctgcaattga ttggtcccaa gtactctgag
    13741 gaaaccattt accaagctgc tgctgctttt gaagcaacaa cagactacca caaacaacaa
    13801 cccgtgattt ttggaggtga caactaatga actttgaaac agtcatcgga cttgaagtcc
    13861 acgtagagct caacaccaat tcaaaaatct tctcacctac ttctgcccac tttggaaatg
    13921 accaaaatgc caacactaac gtgattgact ggtctttccc aggagttcta ccagttctca
    13981 ataaaggggt tgttgatgcc ggtatcaagg ctgctcttgc cctcaacatg gacatccaca
    14041 aaaagatgca ctttgaccgc aagaactact tctatcctga taaccccaaa gcctaccaaa
    14101 tttctcagtt tgatgagcca atcggttata acggctggat tgaagtcgag ctagaagacg
    14161 gtacgaccaa gaaaatcggt atcgaacgtg cccacctaga ggaagacgct ggtaaaaaca
    14221 cccatggtac agatggctac tcttatgttg acctcaaccg ccaaggggtt cccttgattg
    14281 agattgtatc tgaggcagat atgcgttctc ctgaagaagc ctatgcttat ctgacagccc
    14341 tcaaggaagt tatccagtac gctggcattt ctgacgttaa gatggaggaa ggttcgatgc
    14401 gtgtggatgc caacatctcc cttcgtcctt atggtcaaga gaaattcggt accaagactg
    14461 aattgaagaa cctcaactcc ttctcaaacg ttcgcaaggg gcttgaatac gaagtccaac
    14521 gtcaagctga aatacttcgc tcaggtggtc aaatccgcca agaaacacgc cgttacgatg
    14581 aagctaacaa agcaaccatc ctcatgcgtg tcaaggaagg ggctgctgac taccgctact
    14641 tcccagaacc agacctgcct ctctttgaaa tctcagacga gtggattgag gaaatgcgga
    14701 ctgagttgcc agagtttcca aaagaacgtc gtgcgcgtta tgtatctgac cttggtttat
    14761 cagactacga tgctagtcag ttgactgcta ataaagtcac ttctgacttc tttgaaaaag
    14821 ctgttgccct aggtggtgat gccaaacaag tctctaactg gctccaaggg gaagtcgctc
    14881 agttcttgaa tgctgaaggt aaaacactgg aacaaatcga attgacacca gaaaacttgg
    14941 ttgaaatgat tgccatcatc gaagacggta ctatttcatc taagattgcc aagaaagtct
    15001 ttgtccatct agctaaaaat ggcggtggcg cgcgtgaata cgtggaaaaa gcaggtatgg
    15061 ttcaaatttc agatccagct atcttgatcc caatcatcca ccaagtcttt gccgataacg
    15121 aagctgctgt tgccgacttc aagtcaggca aacgtaacgc cgacaaagcc ttcacaggat
    15181 tccttatgaa ggcaaccaaa ggccaagcca acccacaagt tgcccttaaa ctacttgcac
    15241 aggaattggc gaagttgaaa gaaaactaga cagaacaaaa ccagccctaa ggttggtttt
    15301 ttcttgacaa atagaaagaa aacgtttaca atattgcgtg taaagtttcc aaacaagaaa
    15361 actaaaaatc gcaacaataa ggagttattt atatggctac aatgaaggca gctcgctggc
    15421 atgcagcgaa agatgttcgt attcaagaaa tagaagttcc tgaagtactt ccgcaccaag
    15481 taaaagttgc agttaagttc acaggaattt gtggtactga cctccatgaa tttttagatg
    15541 gacctatctt tatcccaaca gatgagcacg tctattctgg tcaaaaagca ccggtaacac
    15601 tgggacatga attttctggt gaaatcatag aagtcggaag cgatgttacc cgtgttaaag
    15661 ttggtgatcg tgttgctgtg gaaccaattc tagctaaaaa taacttagtt ggtgattata
    15721 atttggatcc aaaccttaat tttgtcggtt tggctgcaga cggtggattt gccaaatatt
    15781 gtgttttaga cggtgactta gtacatgtca ttccagatag cttgagctat gagcaagctg
    15841 ctcttactga acccgctgct gttgcagtct atgctgttcg tcaatcttct ttgaaggctg
    15901 gcgatacagc tgttgtcttt ggtttaggcc cgattggtct attaattgta gaagctcttc
    15961 gtgcagctgg tgcttctaag atttatgctg ttgaactatc acctgaacgt caagcaaaag
    16021 ctgaagagtt aggagctatc gttgtccgtc cggaagaagg tgaaacagct gttgaagcta
    16081 ttcatcgttt aacaaacggt ggtgtagatg tttcttatga agtaacgggt gtgccagtag
    16141 ttttaggaca agccttagct gccgtacata aagcaggtga gtgcatggtg gtctctatct
    16201 gggaacgaga agcaaatatt aatccgaatg aatttgcaat ccaagaaaag acactaaaag
    16261 gaatcattgc ttatcgtcat atcttcccta aagtattaga attgatggaa caaggctact
    16321 tctctgctga aaaattagtt actaagaaaa ttaaattgga aaatatcgtc gaagaaggct
    16381 ttatcgaatt aactcaagat aagtcacaaa ttaaaatttt ggtagaacca gaataaaaaa
    16441 tcaatctttt taagacaata ctaacaggtc ggagtaaact tacttcggcc ttttgaaata
    16501 tagtactctt cgaaaatctc ttcaaaccac gtcagcgtca cattaccgta tatatggtta
    16561 ctgacttcgt cagttctatc cacaacctca aaacagtgtt ttgagcagcc tgcggctagc
    16621 ttcctagttt gctctttgat ttccattgag tatgagaaga aatatagtgg atactcttta
    16681 acattaacca ctccacctga ctagccaata ttctttttcg ctcctaccaa ctcccaataa
    16741 ctattttggc tttatttcca gagtatttta tggtaaaatg aagagtaata atatttatta
    16801 aagaggtaaa aacatgattg aagcaagtaa attaaaagct ggtatgacct ttgaaacagc
    16861 tgacggcaaa ttgattcgcg ttttggaagc tagtcaccac aaaccaggta aaggaaacac
    16921 gatcatgcgt atgaaattgc gtgatgtccg tactggttct acatttgaca caagctaccg
    16981 tccagaggaa aaatttgaac aagctattat cgagactgtc ccagctcaat acttgtacaa
    17041 aatggatgac acagcatact tcatgaatac agaaacttac gaccagtacg aaatccctgt
    17101 agtcaatgtt gaaaacgaat tgctttacat ccttgaaaac tctgatgtga aaatccaatt
    17161 ctacggaact gaagtgatcg gtgtcaccgt tcctactact gttgagttga cagttgctga
    17221 aactcaacca tctatcaaag gtgctactgt tacaggttct ggtaaaccag caacgatgga
    17281 aactggactt gtcgtaaacg ttccagactt catcgaagca ggacaaaaac tcgttatcaa
    17341 cactgcagaa ggaacttacg tttctcgtgc ctaatctcta gaaagaggtc attctatggg
    17401 aattgaagaa caacttggcg aaatcgttat cgccccacgt gtacttgaaa aaatcattgc
    17461 tatcgctact gcaaaggtag agggtgttca ctctttttca aacagatcag tgtctgatac
    17521 cctttcaaaa ctttcactcg gccgtggcat ttatcttaaa aacgtggacg aagaactcac
    17581 agcagatatc tatctctacc ttgagtacgg agtaaaagtt cctaaggtag cggttgctat
    17641 ccagaaagct gtcaaagatg ccgtccgtaa tatggctgat gtagaactcg ctgctatcaa
    17701 tattcacgtt gcaggtatcg tcccagataa aacaccaaaa ccagaattga aagatctatt
    17761 tgacgaggac ttcctcaatg actagtccac tattagaatc tagacgccaa ctccgtaaat
    17821 gcgcttttca agctctcatg agccttgagt tcggtacgga tgtcgaaact gcttgtcgtt
    17881 tcgcctatac tcatgatcgt gaatatacgg atgtacaact tccagccttt ttgatagacc
    17941 tcgtttctgg tgttcaagct aaaaaggaag aactagataa gcaaatcact cagcatttaa
    18001 aagcaggttg gaccattgaa cgcttaacgc tcgtggagag aaacctcctt cgcttgggag
    18061 tctttgaaat cacttcattt gacactcctc agctggttgc tgttaatgaa gctatcgagc
    18121 ttgcaaagga cttctccgat caaaaatctg cccgttttat caatggactg ctcagccagt
    18181 ttgtaacaga agaacaataa ggctctttgt caactgtagt gggttgaaga aaagctaagc
    18241 tcgagaaagg acaaatttcg tcctttcttt tttgatgttc agagcgatga aaatccgttt
    18301 tttgaagttt tcaaagttcc gaaaaccaaa ggcattgcgc ttgataagtt tgatgagatt
    18361 attggtcgct tccagtttgg cattagaata gtgtagttga agggcgttga caatcttttc
    18421 tttatctttg aggaaggttt taaagacagt ctgaaaaata ggatgaacct gcttaagatt
    18481 gtcctcaata agtccgaaaa atttctctgg ttccttattc tggaagtgaa aaagcaagag
    18541 ctgatagagt tgatagtggt gtttcaagtc ttccgaataa ctcaaaagct tgtttaaaat
    18601 ctctttattg gttaagtgca tacgaaaagt aggacgataa aaacgtttat cactcagttt
    18661 acggctatcc tgttgaatga gtttccagta gcgcttgata gccttgtatt catgggattt
    18721 tcgatgaaac tgattcatga tttggacacg cacacgactc atagcacggc taagatgttg
    18781 tacaatgtga aagcgatcaa gaacgatttt agcattcggg agtgaaacag tctgggaaac
    18841 tgtttcagcc tgagcctaga aatttgaaag cgaagctgtt tagccaagtc atagtaaggg
    18901 ctaaacatat ccatagtaat gattttcact tgacaacgaa cggctctatc gtagcgaaga
    18961 aagtgatttc ggatgacagc ttgtgttcta ccttcaagaa cagtgatgat atcgagcttt
    19021 tcaaaatctt gcgcaataaa gctcatctcc atctcccgat tgaaacagtc actccccgga
    19081 ctgtttcaac gtcccaagac ataatcttag gcagatttct aaaattacac tcaaagtgga
    19141 agtcattgag ctttcgaatg acagttgaag ttgagatgga aagctgatgg gcaatatcag
    19201 tcatagaaat cttttcaatt aacttttgag caatcttttg gttgatgata cgagggattt
    19261 gatgattctt cttgacgata gaagtttcag cgaccatcat ttttgaacag tgatagcact
    19321 tgaatcgacg ctttctaagg agaattctag
//
LOCUS       DBEJAU010000042        19299 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC323 isolate 683620
            SAMN38261939-rid24807223.denovo.042, whole genome shotgun sequence.
ACCESSION   DBEJAU010000042 DBEJAU010000000
VERSION     DBEJAU010000042.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261939
            Sequence Read Archive: SRR26833919
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 19299)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 19299)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576303.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576303.1
            Genome Coverage       :: 154x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/19/2025 01:05:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,121
            CDSs (total)                      :: 2,078
            Genes (coding)                    :: 1,943
            CDSs (with protein)               :: 1,943
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 36
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 72 of 135
            Pseudo Genes (incomplete)         :: 63 of 135
            Pseudo Genes (internal stop)      :: 51 of 135
            Pseudo Genes (multiple problems)  :: 46 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..19299
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261939-rid24807223.denovo.042"
                     /strain="GPSC323"
                     /isolate="683620"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            complement(<1..498)
                     /locus_tag="ACL29Z_001565"
     CDS             complement(<1..498)
                     /locus_tag="ACL29Z_001565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013852041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ClbS/DfsB family four-helix bundle protein"
                     /protein_id="HGR0069847.1"
                     /translation="MRTYENKEELKAEIEKTFEKYILEFDNIPENLKDKRADEVDRTP
                     AENLAYQVGWTNLVLKWEEDERKGLQVKTPSDKFKWNQLGELYQWFTDTYAHLSLQEL
                     KAKLNENINSISAMIDSLSEEELFEPHMRKWADEATKTATWEVYKFIHVNTVAPFGTF
                     RTKIRK"
     gene            complement(535..663)
                     /locus_tag="ACL29Z_001566"
                     /pseudo
     CDS             complement(535..663)
                     /locus_tag="ACL29Z_001566"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001267199.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="CD1845 family protein"
     gene            complement(719..1588)
                     /gene="rsmI"
                     /locus_tag="ACL29Z_001567"
     CDS             complement(719..1588)
                     /gene="rsmI"
                     /locus_tag="ACL29Z_001567"
                     /EC_number="2.1.1.198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001166894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008649 - rRNA methyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0008757 - S-adenosylmethionine-dependent
                     methyltransferase activity [Evidence IEA];
                     GO_process: GO:0000451 - rRNA 2'-O-methylation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA
                     (cytidine(1402)-2'-O)-methyltransferase"
                     /protein_id="HGR0069848.1"
                     /translation="MQIQKSFKGQSPYGKLYLVATPIGNLDDMTFRAIQTLKEVDWIA
                     AEDTRNTGLLLKHFDISTKQISFHEHNAKEKIPDLIGFLKAGQSIAQVSDAGLPSISD
                     PGHDLVKAAIEEEIAVVTVPGASAGISALIASGLAPQPHIFYGFLPRKSGQQKQFFDS
                     KKDYPETQIFYESPHRVADTLENMLEVYGDRSVVLVRELTKIYEEYQRGTISELLESI
                     AETPLKGECLLIVEGASQGVEEKDEEDLFVEIQTRIQQGVKKNQAIKEVAKIYQWNKS
                     QLYAAYHDWEEKQ"
     gene            complement(1591..1908)
                     /gene="yabA"
                     /locus_tag="ACL29Z_001568"
     CDS             complement(1591..1908)
                     /gene="yabA"
                     /locus_tag="ACL29Z_001568"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000358230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA replication initiation control protein YabA"
                     /protein_id="HGR0069849.1"
                     /translation="MDKKELFDALDDFSQQLLVTLADVEAIKKNLKSLVEENTALRLE
                     NSKLRERLGEVEADAPVKAKHVRESVRRIYRDGFHVCNDFYGQRREQDEECMFCDELL
                     YRE"
     gene            complement(1948..2838)
                     /locus_tag="ACL29Z_001569"
     CDS             complement(1948..2838)
                     /locus_tag="ACL29Z_001569"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000806705.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA];
                     GO_function: GO:0008408 - 3'-5' exonuclease activity
                     [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit delta'"
                     /protein_id="HGR0069850.1"
                     /translation="MKQDQLKAWQPDQFDRFVRILEQDQLNHAYLFSGFFGSLEMAQF
                     LAKSLFCTDKVGVLPCEKCRSCKLIEQEEFPDVTLIKPVNQVIKTERIRELVGQFSQA
                     GIESQQQVFIIEQADKMHPNAANSLLKVIEEPQSEVYIFFLTSDEEKMLPTIRSRTQI
                     FHFKKQEEKLILLLEQMGLVKKKATLLAKFSQSRAEAEKLANQASFWTLVDESERLLT
                     WLVAKKKESYLQVAKLANLADDKEKQDQVLRILEVLCGQDLLQVRVRVILQDLLEARK
                     MWQANVSFQNAMEYLVLKEI"
     gene            complement(2835..3473)
                     /gene="tmk"
                     /locus_tag="ACL29Z_001570"
     CDS             complement(2835..3473)
                     /gene="tmk"
                     /locus_tag="ACL29Z_001570"
                     /EC_number="2.7.4.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004261378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004798 - thymidylate kinase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006233 - dTDP biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dTMP kinase"
                     /protein_id="HGR0069851.1"
                     /translation="MSKGFLVSLEGPEGAGKTSVLEALLPILEEKGVEVLTTREPGGV
                     LIGEKIREVILDPSHTQMDAKTELLLYIASRRQHLVEKVLPALEAGKLVIMDRFIDSS
                     VAYQGFGRGLDIEAIDWLNQFATDGLKPDLTLYFDIEVEEGLARIAANSDREVNRLDL
                     EGLDLHKKVRQGYLSLLDKEGNRIVKIDASLPLEQVVETTKAVLFDGMGLAK"
     gene            complement(3589..4386)
                     /gene="proC"
                     /locus_tag="ACL29Z_001571"
     CDS             complement(3589..4386)
                     /gene="proC"
                     /locus_tag="ACL29Z_001571"
                     /EC_number="1.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254731.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004735 - pyrroline-5-carboxylate
                     reductase activity [Evidence IEA];
                     GO_process: GO:0006561 - proline biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyrroline-5-carboxylate reductase"
                     /protein_id="HGR0069852.1"
                     /translation="MKIGFIGLGNMGASLAKSVLQTRTSDEILLANRSQAKVDAFIAD
                     FGGQASSNEEMFAEADVIFLGVKPAQFSELLSQYQTILEKRESLLLISMAAGLTLEKL
                     ASLIPSQHRIIRMMPNTPASIGQGVISYALSPNCRAEDSELFCQLLSKAGLLVELGES
                     LINAATGLAGCGPAFVYLFIEALADAGVQTGLSRETALKMAAQTVVGAGQLVLESQQH
                     PGVLKDQVCSPGGSTIAGVASLEAHAFRGTVMEAVHQAYKRTQELGK"
     gene            complement(4390..5652)
                     /locus_tag="ACL29Z_001572"
     CDS             complement(4390..5652)
                     /locus_tag="ACL29Z_001572"
                     /EC_number="1.2.1.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004350 - glutamate-5-semialdehyde
                     dehydrogenase activity [Evidence IEA];
                     GO_function: GO:0016620 - oxidoreductase activity, acting
                     on the aldehyde or oxo group of donors, NAD or NADP as
                     acceptor [Evidence IEA];
                     GO_process: GO:0006561 - proline biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate-5-semialdehyde dehydrogenase"
                     /protein_id="HGR0069853.1"
                     /translation="MVSRQEQFEQVQAVKKSINTASEEVKNQALLAMADHLVAATEEI
                     LAANALDMAAAKGKISDVMLDRLYLDADRIEAMARGIREVVALPDPIGEVLETSQLEN
                     GLVITKKRVAMGVIGIIYESRPNVTSDAAALTLKSGNAVVLRSGKDAYQTTHAIVTAL
                     KKGLETTTIHPNVIQLVEDTSRESSYAMMKAKGYLDLLIPRGGAGLINAVVENAIVPV
                     IETGTGIVHVYVDKDADEDKALSIINNAKTSRPSVCNAMEVLLVHENKAASILPRLDQ
                     MLVAERKEAGLEPIQFRLDSKASQFVSGQAAETQDFDTEFLDYVLAVKVVSSLEEAVA
                     HIESHSTHHSDAIVTENAEVAAYFTDQVDSAAVYVNASTRFTDGGQFGLGCEMGISTQ
                     KLHARGPMGLKELTSYKYVVAGDGQIRE"
     gene            complement(5662..6771)
                     /gene="proB"
                     /locus_tag="ACL29Z_001573"
     CDS             complement(5662..6771)
                     /gene="proB"
                     /locus_tag="ACL29Z_001573"
                     /EC_number="2.7.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000875748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004349 - glutamate 5-kinase activity
                     [Evidence IEA];
                     GO_process: GO:0006561 - proline biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate 5-kinase"
                     /protein_id="HGR0069854.1"
                     /translation="MKYKRIVFKVGTSSLTNEDGSLSRSKVKDITQQLAMLHEAGHEL
                     ILVSSGAIAAGFGALGFKKRPTKIADKQASAAVGQGLLLEEYTTNLLLRQIVSAQILL
                     TQDDFVDKRRYKNAHQALSVLLNRGAIPIINENDSVVIDELKVGDNDTLSAQVAAMVQ
                     ADLLVFLTDVDGLYTGNPNSDPRAKRLERIETINREIIDMAGGAGSSNGTGGMLTKIK
                     AATIATESGVPVYICSSLKSDSMIEAAEETEDGSYFVAQEKGLRTQKQWLAFYAQSQG
                     SIWVDKGAAEALSQHGKSLLLSGIVEAEGAFSYGDIVTVFDKESGKSLGKGRVQFGAS
                     ALEDMLRSQKAKGVLIYRDDWISITPEIQLLFTEF"
     gene            complement(6872..8755)
                     /gene="cbpE"
                     /locus_tag="ACL29Z_001574"
                     /gene_synonym="pce"
     CDS             complement(6872..8755)
                     /gene="cbpE"
                     /locus_tag="ACL29Z_001574"
                     /gene_synonym="pce"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000728269.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphorylcholine esterase CbpE"
                     /protein_id="HGR0069855.1"
                     /translation="MKKKLTSLALVGAFLGLSWYGNVQAQESSGNKIHFINVQEGGSD
                     AIILESNGHFAMVDTGEDYDFPDGSDSRYPWREGIETSYKHVLTDRVFRRLKELGVQK
                     LDFILVTHTHSDHIGNVDELLSTYPVDRVYLKKYSDNRITNFERLWDNLYGYDKVLQT
                     ASEKGVSVIQNITQGDAHFQFGDMDIQLYNYENETDSSGELKKIWDDNSNSLISVVKV
                     NGKKIYLGGDLDNVHGAEDKYGPLIGKVDLMKFNHHHDTNKSNTKDFIKNLSPSLIVQ
                     TSDSLPWKNGVDSEYVNWLKERGIERINAASKDYDATVFDIRQDGLVNISTSYKPIPS
                     FQAGWHKSSYGNWWYQAPDSTGEYAVGWNEIKGEWYYFNQTGILLQNQWKKWNNRWFY
                     LTDSGVAAKNWKKIAGIWYYFNKENQMEIGWIQDKEQWYYLDVDGSMKTGWLQYKGQW
                     YYFAPSGEMKTGWVKDKEAWYYMDSTGIMKTGEIEVAGHHYYLEESGAMKQGWLKKAN
                     DWYFYKTDGSRAIGWIKDKDKWYFLKENGQLLVNGKTPEGYTVDSSGAWLVDVPIEKS
                     ATIKTTSHSEIKESKEVVKKDLENKETSQHESVTNSSTSQDLTSSTSQSSETSVNKSE
                     SEQ"
     gene            complement(8758..9645)
                     /locus_tag="ACL29Z_001575"
     CDS             complement(8758..9645)
                     /locus_tag="ACL29Z_001575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0009982 - pseudouridine synthase activity
                     [Evidence IEA];
                     GO_process: GO:0001522 - pseudouridine synthesis [Evidence
                     IEA];
                     GO_process: GO:0009451 - RNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HGR0069856.1"
                     /translation="MEIKIETGGLRLDKALSDLSELSRSLANEQIKSGQVLVNGQVKK
                     AKYTVQEGDVVTYHVPEPEVLEYVAEDLPLEIVYQDEDVAVVNKPQGMVVHPSAGHTS
                     GTLVNALMYHIKDLSGINGVLRPGIVHRIDKDTSGLLMIAKNDDAHLVLAQELKDKKS
                     LRKYWAIVHGNLPNDRGVIEAPIGRSEKDRKKQAVTAKGKPAVTRFHVLERFGDYSLV
                     ELQLETGRTHQIRVHMAYIGHSVAGDEVYGPRKTLKGHGQFLHAKTLGFTHPRTGKTL
                     EFKADIPEIFKETLERLRK"
     gene            complement(9635..10096)
                     /gene="lspA"
                     /locus_tag="ACL29Z_001576"
     CDS             complement(9635..10096)
                     /gene="lspA"
                     /locus_tag="ACL29Z_001576"
                     /EC_number="3.4.23.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0004190 - aspartic-type endopeptidase
                     activity [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA];
                     GO_process: GO:0009306 - protein secretion [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase II"
                     /protein_id="HGR0069857.1"
                     /translation="MKKRAIVAVIVLLLIGLDQLVKSYIVQQIPLGEVRSWIPNFVSL
                     TYLQNRGAAFSILQDQQLLFAVITLVVVIGAIWYLHKHMEDSFWMVLGLTLIIAGGLG
                     NFIDRVSQGFVVDMFHLDFINFAIFNVADSYLTVGVIILLIAMLKEEINGN"
     gene            complement(10093..11001)
                     /locus_tag="ACL29Z_001577"
     CDS             complement(10093..11001)
                     /locus_tag="ACL29Z_001577"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001025716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HGR0069858.1"
                     /translation="MNIQQLRYVVAIANSGTFREAAEKMYVSQPSLSISVRDLEKELG
                     FKIFRRTSSGTFLTRRGMEFYEKAQELVKGFDIFQNQYANPEEEKDEFSVASQHYDFL
                     PPTITAFSERYPDYKNFRIFESTTVQILDEVAQGHSEIGIIYLNNQNKKGIMQRVEKL
                     GLEVIELIPFHTHIYLREGHPLAQKDELVMEDLADLPTVRFTQEKDEYLYYSENFVDT
                     SASSQMFNVTDRATLNGILERTDAYATGSGFLDSDSVNGITVIRLKDNLDNRMVYVKR
                     EEVELSQAGTLFVEVMQEYFDQKRKS"
     gene            11030..11191
                     /locus_tag="ACL29Z_001578"
     CDS             11030..11191
                     /locus_tag="ACL29Z_001578"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001842783.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HGR0069859.1"
                     /translation="MIPYFRSFPKRKKEHPILLNYLHYLPFSSQPYFQNQFKKISGYT
                     PLQYRKEKR"
     gene            complement(11243..11914)
                     /locus_tag="ACL29Z_001579"
     CDS             complement(11243..11914)
                     /locus_tag="ACL29Z_001579"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000746014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysostaphin resistance A-like protein"
                     /protein_id="HGR0069860.1"
                     /translation="MKKRAIQILLALSLIFYKSTWFWRVFNHLAKPYLPASREFFQIL
                     LLMESGVLFLAVIYLLVFAGKKIFHFKWQLRYFIYLLLGYIISYMSDFLFSYFISLSS
                     NQISLNETVEMMGRQEFPYFLLIVCFIAPIAEELIYRGVIMTTFFKNSPWYGDVLLSA
                     IIFGYIHINFALTPLAFFIYASGGLILALLYRMTKNLYYPILVHILINITAFWDVWLL
                     LFSGS"
     gene            complement(11968..12189)
                     /locus_tag="ACL29Z_001580"
     CDS             complement(11968..12189)
                     /locus_tag="ACL29Z_001580"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000602450.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SP_0924 family bacteriocin-like peptide"
                     /protein_id="HGR0069861.1"
                     /translation="MILMTKNINLTNEELELIQGGADPYGKNPNGRYDWEIEPVLTLP
                     VHGFCPRGTYDLGYIGGGNHLCKGSAARF"
     gene            12461..13270
                     /locus_tag="ACL29Z_001581"
     CDS             12461..13270
                     /locus_tag="ACL29Z_001581"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000593565.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HGR0069862.1"
                     /translation="MIKLLALDMDGTLLNEAKEIPQAHIAAIHQAIEKGVKLVLCTGR
                     PLFGVLPYYKKLGLDLQNEYVIVNNGCSTHQTSDWGLVDWQELSPADIEYLYDIAEKS
                     DVQLTLFDESHYFVLGGKPNQVIENDAKLVFSDLTEISLEEATSGKLRMFQGMFLGTK
                     EQTDDFEQRFAEELCQRFSGVRSQPVIYEAMPLGTTKATALSRLAEILKIDSSEIMAM
                     GDANNDIEMLQFAGLGIAMGNASDYVKSLADAVTSSNEEDGVARAIEKYIL"
     gene            complement(13451..14326)
                     /gene="aguB"
                     /locus_tag="ACL29Z_001582"
     CDS             complement(13451..14326)
                     /gene="aguB"
                     /locus_tag="ACL29Z_001582"
                     /EC_number="3.5.1.53"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001246759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0050126 - N-carbamoylputrescine amidase
                     activity [Evidence IEA];
                     GO_process: GO:0009446 - putrescine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="N-carbamoylputrescine amidase"
                     /protein_id="HGR0069863.1"
                     /translation="MRNVRVATIQMQCAKDVATNIQTAERLVRQAAEQGAQIILLPEL
                     FEHPYFCQERQYDYYQYAQSVAENTAIQHFKVIAKELQVVLPISFYEKDGNVLYNSIA
                     VIDADGEVLGVYRKTHIPDDHYYQEKFYFTPGNTGFKVWNTRYAKIGIGICWDQWFPE
                     TARCLVLNGAELLFYPTAIGSEPILDTDSCGHWQRTMQGHAAANIVPVIAANRYGLEE
                     VTPSEENGGQSSSLDFYGSSFMTDETGAILERAERQEEAVLLATYDLDKGASERLNWG
                     LFRDRRPEMYRQITD"
     gene            complement(14336..15421)
                     /gene="aguA"
                     /locus_tag="ACL29Z_001583"
     CDS             complement(14336..15421)
                     /gene="aguA"
                     /locus_tag="ACL29Z_001583"
                     /EC_number="3.5.3.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0047632 - agmatine deiminase activity
                     [Evidence IEA];
                     GO_process: GO:0009446 - putrescine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="agmatine deiminase"
                     /protein_id="HGR0069864.1"
                     /translation="MMDSPKKLGYHMPAEYEPHHGTLMIWPTRPGSWPFQGKAAKRAF
                     TQIIETIAEGERVYLLVEQAYLSEAQSYLGDKVVYLDIPTNDAWARDTGPTILVNDKG
                     KKLAVDWAFNAWGGTYDGLYQDYEEDDQVASRFAEALERPVYDAKPFVLEGGAIHSDG
                     QGTILVTESCLLSPGRNPNLTKEEIENTLLESLGAEKVIWLPYGIYQDETNEHVDNVA
                     AFVGPAELVLAWTDDENDPQYAMSKADLELLEQETDAKGCHFTIHKLPIPAVRQVVTE
                     EDLPGYIYEEGEEKRYAGERLAASYVNFYIANKAVLVPQFEDVNDQVALDILSKCFPD
                     RKVVGIPARDILLGGGNIHCITQQIPE"
     gene            complement(15418..16545)
                     /gene="nspC"
                     /locus_tag="ACL29Z_001584"
     CDS             complement(15418..16545)
                     /gene="nspC"
                     /locus_tag="ACL29Z_001584"
                     /EC_number="4.1.1.96"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016831 - carboxy-lyase activity [Evidence
                     IEA];
                     GO_process: GO:0045312 - nor-spermidine biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carboxynorspermidine decarboxylase"
                     /protein_id="HGR0069865.1"
                     /translation="MKLEQVPTPAYVIDLVKLEANCRILQYVQEEAGCKVLLAQKAYS
                     LYKTYPLISQYLSGTTASGLYEAKLAREEFPGEVHVFAPAFKDADLEELLEIMDHIVF
                     NSERQLRKHGPRCREAGVSVGLRLNPQCSTQGDHALYDPCAPGSRFGVTIDKIPSDLL
                     DLVDGLHFHTLCEQGADDLQTTLKAVEEQFGPYLHEVKWLNMGGGHHITREGYDVDLL
                     ISEIKRIRKTYNLEIYIEPGEAIALNAGYLATEVLDIVENGMEILVLDASATCHMPDV
                     LEMPYRPSLRNGFEAQEKAHTYRLSSNTCLTGDVIGDYSFENPVQIGDRLYFQDMAIY
                     SFVKNNTFNGIGLPSLYLMDEQGDCSLLKAFGYQDFKGRLS"
     gene            complement(16545..17804)
                     /locus_tag="ACL29Z_001585"
     CDS             complement(16545..17804)
                     /locus_tag="ACL29Z_001585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000088792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="saccharopine dehydrogenase family protein"
                     /protein_id="HGR0069866.1"
                     /translation="MSRLLVIGCGGVAQVAISKICQDSETFTEIMIASRTKSKCDDLK
                     AKLEGKTSTKIETAALDADKVEEVITLIESYKPEAVLNVALPYQDLTIMDACLATGVH
                     YIDTANYEAEDTEDPEWRAIYEKRCKELGFTAYFDYSWQWAYQEKFKEAGLTALLGSG
                     FDPGVTSVFSAYALKHYFDEIHYIDILDCNGGDHGYPFATNFNPEINLREVSAPGSYW
                     EDGKWVEVEAMSIKREYDFPQVGQKDMYLLHHEEIESLAKNIPGVKRIRFFMTFGQSY
                     LTHMKCLENVGLLRTDTINFNGQEIVPIQFLKALLPDPASLGPRTVGKTNIGCIFTGV
                     KDGVEKTIYIYNVCDHQECYAEVGSQAISYTTGVPAMIGTKLVMNGTWKQAGVYNLEE
                     LDPDPFMEALNEYGLPWVVVENPQMVD"
     gene            complement(17801..18661)
                     /gene="speE"
                     /locus_tag="ACL29Z_001586"
     CDS             complement(17801..18661)
                     /gene="speE"
                     /locus_tag="ACL29Z_001586"
                     /EC_number="2.5.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyamine aminopropyltransferase"
                     /protein_id="HGR0069867.1"
                     /translation="MDLWFSEVHTPDVKLSLRTAKQLYAGKSEWQDIEVLDTPAFGKI
                     LILNGHVLFSDADDFVYNEMTVHVPMAVHPNPKKVLVIGGGDGGVAQVLTLYPELEQI
                     DIVEPDEMLVEVCREYFPDFAAGLDDPRVTIYYQNGLRFLRNCEDDYDIIINDATDPF
                     GHTEGLFTKEFYGNSYRALKEDGIMIYQHGSPFFDEDESACRSMHRKVNQAFPISRVY
                     QAHIPTSPAGYWLFGFASKKYHPVKDFDKEGWKKRQLFTEYYTANLHVGAFMLPKYVE
                     DILEEEEGKK"
     gene            18917..>19299
                     /locus_tag="ACL29Z_001587"
     CDS             18917..>19299
                     /locus_tag="ACL29Z_001587"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001841243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HGR0069868.1"
                     /translation="MLYVGIDVAKNKHDVTALNVPGKTVLKPLTFSNNKAGFELLDLS
                     LRQLNQDCLIALENTGHYAFNLLNFLHEQGYKVYTYNPLLIKEFAKSLSLRKTKTDKK
                     DAHGIALKLLSDPNREQFQHDNRQV"
BASE COUNT         5565 a         4488 c         3489 g         5757 t
ORIGIN      
        1 ttttctgatt ttagttctga aagttccaaa aggtgcaacc gtatttacat gaataaactt
       61 atacacttcc caagtcgctg ttttagtcgc ttcatcagcc cactttctca tatgcggttc
      121 aaataattct tcctcactca acgaatcaat cattgcagag atagaattaa tattttcatt
      181 taattttgct ttcaactctt gcagagataa atgagcgtag gtatctgtga accactgata
      241 taattcacca agttgattcc atttaaattt atccgatggt gtttttactt gaagcccctt
      301 tctttcatct tcttcccatt taagaaccaa gttggtccaa ccaacctgat aagcaaggtt
      361 ttctgctgga gttctgtcaa cttcatcagc tctcttatct tttaaatttt ctggaatatt
      421 atcaaattct aaaatatatt tctcaaatgt tttctctatc tcagctttta gttcttcttt
      481 attttcgtat gttcgcaaaa aatcaccttc tttctgattt atcaatcctt tgatttaaaa
      541 tgaccttatt tttctattta taccttctag gaacgctata actgctgctc caaccatcgg
      601 tattccgtat gggcttaata aaaaacttaa taccaaagct tctataccaa gtgatacatc
      661 tttatattat catcactaat taagttaaac agacagaatt attacatcct gtctcccttt
      721 attgtttttc ttcccagtcg tggtaggcag cgtagagctg acttttattc cactggtaaa
      781 tcttagcgac ttccttgata gcttggtttt tcttcacacc ttgctggatg cgggtttgaa
      841 tttctacgaa caagtcttcc tcgtcctttt cctccacacc ctgactggca ccctcaacaa
      901 tgagaagaca ttcgcccttg agtggcgttt cagcaatgct ttctaataac tcagagatag
      961 tacctcgttg gtattcttca tagattttgg tcaattccct gaccaagaca acggagcggt
     1021 caccgtagac ttctagcata ttttccaatg tatctgccac acgatggggc gattcataaa
     1081 aaatctgagt ttcaggatag tcttttttcg agtcgaaaaa ttgcttttgc tggcctgatt
     1141 ttctcggtaa aaagccgtaa aagatatgtg gctgcggcgc taaaccactg gcaatcaagg
     1201 cggaaattcc tgcagaggca cctggaactg taacaactgc aatttcttcc tcaatagctg
     1261 ccttaaccaa atcatgacca gggtctgaaa tgctaggcaa accggcatca gagacctgag
     1321 caatactttg ccctgctttc aagaaaccaa tcaaatcagg aattttttcc ttggcattgt
     1381 gctcatgaaa actgatctgc ttggtggaaa tgtcaaaatg cttgagcaaa agacctgtat
     1441 tgcgcgtatc ctcagcagca atccaatcta cttctttcaa ggtctggata gctcgaaaag
     1501 tcatatcatc tagattgcca atcggcgttg ccactagata cagcttgcca tagggagact
     1561 gccccttaaa acttttttga atctgcatgc ctactccctg tatagcaact cgtcacaaaa
     1621 catacattcc tcgtcctgct ctcgacgttg tccataaaaa tcattacata cgtgaaatcc
     1681 atcacggtaa atacgacgga cactttcgcg aacatgcttg gccttgacgg gagcgtctgc
     1741 ttccacctca cccaagcgtt ctcgcaactt actattttcc aagcgaagag ctgtattttc
     1801 ttctaccaag ctcttgagat ttttcttgat ggcttccaca tcggctaagg ttaccaataa
     1861 ttgttgggaa aaatcatcca gcgcgtcaaa taattctttt ttgtccataa aacagccctt
     1921 tcctttcttt atcattcatt tttgagttta tatttctttc aagaccagat attccatggc
     1981 attttgaaag ctgacattag cttgccacat ttttctagct tctagtaaat cttgtagaat
     2041 cactcttact cttacctgca agaggtcctg cccacagaga acttcaagaa tccgtaaaac
     2101 ctgatcctgt ttttccttat catctgccaa gttggctaat ttggcaacct gtagataact
     2161 ttcttttttc ttagctacta accaagtcag caggcgttca ctttcatcga ccaaggtcca
     2221 aaaacttgcc tgattagcca acttttctgc ttcagctcgc gattgactaa acttagctaa
     2281 aagagtcgct tttttcttaa caagtcccat ttgttctaag agtaagataa gtttttcttc
     2341 ttgcttttta aagtggaaga tctgagtccg acttcggatt gtcggtaaca tcttttcctc
     2401 atcgctagtc aagaagaaaa tataaacttc actctggggt tcttcgatga ccttgagcag
     2461 agaattggct gcgttgggat gcattttatc cgcttgctcg atgataaaga cctgttgctg
     2521 gctttcaatc cctgcttgag aaaactgtcc caccaattcc cgaatgcgtt ctgtcttgat
     2581 gacctgattg actggcttaa tcaaggtgac atctggaaac tcttcctgtt caatcagctt
     2641 gcaacttcgg catttctcac atggtaagac gccaacttta tccgtacaaa agaggctctt
     2701 agctaaaaat tgcgccattt ccaagcttcc aaagaaacct gaaaagagat aggcgtgatt
     2761 gagctggtct tgttctaaga tacggacaaa acggtcaaac tgatctggtt gccaagcctt
     2821 tagttgatct tgtttcattt ggccaagccc attccgtcaa acaagacagc cttggtagtt
     2881 tccacaactt gctccaaagg gagactagca tcaatcttga caatgcgatt tccctcttta
     2941 tccagaagag aaaggtagcc ttgacgaact tttttatgca agtccaaccc ttccaaatcc
     3001 aaacgattaa cctcgcggtc actattagca gcaatacgag ccagcccttc ttccacctcg
     3061 atgtcaaaat agagtgtcaa atcgggtttg agaccatctg tcgcaaactg attgagccag
     3121 tcaatggctt caatatctaa gccacgacca aatccctgat aggcaacaga actatcgata
     3181 aaacgatcca tgatgaccaa cttgccagct tcaagggctg gaagaacttt ttccaccaaa
     3241 tgctgtctgc gactggcaat atagagaagt agctctgttt tagcatccat ctgagtatga
     3301 cttggatcca aaatcacttc ccgaatcttc tccccaatca agactccgcc aggttcacgg
     3361 gtcgtcaaca cctctactcc tttttcctct aaaattggta gcagagcctc taaaacactg
     3421 gtcttgcctg ctccctctgg tccctcaaga gagactaaaa atccttttga catgtctaac
     3481 tcatttcttt tttactactt ctattctatc aaaaaaatag gggtttgtga caatcttttt
     3541 gtgtcttctc atttcagcca ccataaaaga ggcagtcaaa gctacctctt atttacctag
     3601 ttcttgtgtt cgtttatagg cttgatgaac tgcctccatg actgtgcctc gaaaagcatg
     3661 cgcttctagg cttgctacgc cagcaatagt cgaaccgcct ggactacaaa cttgatcttt
     3721 caaaactcca ggatgttgct ggctttctag gaccaattgc ccagctccta ccacagtttg
     3781 ggctgccatt ttcaaggctg tttctcgtga taatcccgtc tgaacacctg catctgccaa
     3841 ggcttcaata aagagataga caaaggctgg tccacagcct gcaagacctg tcgctgcatt
     3901 gattaagctt tctcctaatt caaccaagag accagccttg gataaaagct gacaaaagag
     3961 ctcactgtcc tcagccctgc aattaggaga caaggcataa ctaatcactc cttgcccgat
     4021 agaagcaggg gtattaggca tcatacgaat aattcggtgt tgacttggga taagacttgc
     4081 tagtttttct aaggtcaatc cagctgccat cgaaatcaaa agaagacttt ctcttttttc
     4141 aaggatggtc tggtattgag aaagcagttc agaaaactga gcaggcttaa ctcctagaaa
     4201 aatcacatct gcttctgcaa acatttcttc attgctggaa gcctgaccac caaagtctgc
     4261 aatgaaagca tctaccttag cttgactacg attggcaagg agaatctcat ctgacgtcct
     4321 agtctgcaag acagattttg ccaagctagc acccatattc cccaaaccga taaatccaat
     4381 cttcatctct tactccctta tctgcccatc accagcaacc acatacttgt agctggtcaa
     4441 ctctttcaag cccattggac cacgcgcgtg caatttctga gtagaaatcc ccatttcaca
     4501 accaagacca aattgtcctc catctgtgaa acgagttgag gcattaacat acaccgctgc
     4561 agagtccact tgatctgtaa agtatgctgc aacttcagca ttttccgtca caatagcatc
     4621 cgaatgatgg gtgctgtggg attcaatgtg cgcaaccgct tcttctaaac tgctcacaac
     4681 cttaacagca aggacatagt ctaaaaactc ggtgtcaaag tcttgggtct cagctgcttg
     4741 acctgaaaca aactggcttg ctttgctatc caagcggaat tgaattggtt ccagtccagc
     4801 ttccttacgc tctgcaacca gcatttgatc caagcgagga aggatgcttg ctgccttgtt
     4861 ttcatgaacc agcagaacct ccatggcatt acaaacagaa ggacgactgg ttttagcatt
     4921 gttgatgata gacagcgcct tgtcttcgtc tgcatcctta tccacataga catggacaat
     4981 cccagtccct gtctcgataa caggtacaat cgcattctca accactgcat tgatcaagcc
     5041 agctcctcca cgaggaatga gaaggtctag atagcccttg gccttcatca tagcataact
     5101 actttcacgg ctagtatcct ccaccagttg aatcacattt ggatgaatag tagtcgtctc
     5161 caagcccttc ttcaaggctg tgacaatggc atgggttgtt tgataggcat ccttaccact
     5221 acgaagaaca accgcatttc cactcttaag agtcaaagca gccgcatcag acgtcacatt
     5281 tggacggctt tcatagataa taccgatgac acccatagct acacgttttt ttgtgataac
     5341 caaaccattt tcaagctgac ttgtttctaa aacttcaccg attggatctg gtaaggcaac
     5401 cacttcacga attcctcttg ccatcgcttc tatacgatct gcatccaaat aaagacgatc
     5461 caacatcaca tctgagattt tccccttagc cgctgccata tcgagggcat tagccgctaa
     5521 aatttcctca gtagcagcca ctaagtgatc agccatggct agcaaggctt ggtttttcac
     5581 ttcttcacta gctgtgttaa tcgatttttt aacagcctgt acctgttcaa attgttcttg
     5641 tctactcacc atagtttacc tctaaaattc tgtaaaaagt agttggattt caggagtaat
     5701 ggaaatccag tcgtcacggt aaatcaagac acccttggct ttttgagaac gcaacatatc
     5761 ctccaaagca gatgctccaa attgcacgcg tccttttcca agtgattttc cactttcctt
     5821 gtcaaatact gtcacgatat caccgtaaga aaaggctcct tctgcttcaa cgataccaga
     5881 taagagaaga ctctttccat gttgagagag agcttccgca gcccctttat caacccaaat
     5941 agaaccttga ctctgagcat agaaggcaag ccattgtttc tgggtacgaa gccccttctc
     6001 ttgagcaaca aaataagaac catcctcggt ctcctctgcc gcctcaatca tggaatctga
     6061 tttcaaggat gagcagatat aaacaggaac tcctgattcc gtcgcgatag ttgcagcctt
     6121 gattttggtt aacatacccc cagttccgtt tgacgaacct gctccaccag ccatatcaat
     6181 aatctcacga ttgatggtct cgattctctc caagcgtttg gctcttggat ctgaattagg
     6241 atttccagta tagagaccgt ccacatctgt caagaaaact aaaaggtctg cttggaccat
     6301 cgccgctact tgagcactta gagtgtcatt gtccccaacc ttgagctcat caataacgac
     6361 actatcattc tcattgatga taggaattgc cccacggttg agcaaaaccg acaaagcctg
     6421 atgggcattt ttataacgac gcttatccac aaagtcatct tgggtcagca agatttgtgc
     6481 agaaacgatt tgacgcaaga gaagattggt cgtatattct tccaacaaaa gtccctgccc
     6541 taccgctgct gaagcctgtt tatcagcaat tttagtcgga cgctttttaa atcctaaggc
     6601 tccaaaacca gccgcaatgg cacctgaaga caccaaaatc aactcatgac cagcctcgtg
     6661 cagcatagcc aactgctggg taatatcctt taccttacta cgtgataaac ttccatcctc
     6721 atttgtcaga gaagaagtac ccaccttaaa gacaatccgt ttgtatttca tagtctcact
     6781 ccgattattc atatttatcc attataacat gaataacagg aaatagaaaa gagttgatag
     6841 gaaaaagaag gccctaaaac cttcttttct actactgttc tgattccgat ttgtttacac
     6901 tcgtttcaga gctttgtgaa gttgaggatg tcaaatcttg actagttgaa gaatttgtaa
     6961 cactttcatg ttgactcgtt tctttatttt caagatcctt tttcactact tctttggatt
     7021 cttttatttc tgaatgactt gtagttttaa ttgtagcaga tttctcgatc ggaacatcca
     7081 ctaaccaggc accacttgaa tccacagtat agccttctgg tgtcttacca ttcacaagta
     7141 attgaccatt ttctttcaag aagtaccatt tatccttgtc tttaatccaa cctatagctc
     7201 gtgaaccatc tgtcttgtag aaataccaat catttgcctt tttaagccag ccttgcttca
     7261 tagctcctga ttcttctaga tagtaatgat gtccagcaac ttctatctca cctgtcttca
     7321 tgataccagt agaatccata tagtaccagg cttctttatc ttttacccag cccgttttca
     7381 tttcccctga tggagcaaag taataccatt gccccttata ttgaagccaa cctgtcttca
     7441 tagagccatc aacatccaaa taataccact gctctttatc ttgaatccaa ccaatttcca
     7501 tctggttttc tttgttaaaa taataccaga ttccagcgat tttcttccaa tttttagcag
     7561 caacaccaga gtctgtcaaa tagaaccaac gattgttcca ttttttccat tgattctgta
     7621 ataagatacc cgtttggtta aagtaatacc attcaccctt aatttcattc caaccgacag
     7681 catattctcc tgtagaatca ggcgcttgat accaccagtt tccatatgaa ctcttatgcc
     7741 aaccagcttg aaaacttgga atcggcttgt aggaagttga aatgtttact aaaccgtctt
     7801 gtcgaatatc aaaaactgtc gcatcatagt ctttgctggc tgcgttgatt ctctcaattc
     7861 ctcgttcttt gagccaatta acatactcac tatcaacacc atttttccaa ggtagactat
     7921 ccgaagtttg aacaatcaaa ctcggactca aatttttaat gaaatccttg gtatttgatt
     7981 tgttggtatc atggtgatga ttaaacttca tcaaatcaac ttttccaatg agaggaccat
     8041 acttgtcttc tgctccatga acattatcta agtcgccccc aaggtaaatt ttcttgccat
     8101 tgacttttac cacactaatc aaggaattgg aattatcatc ccaaattttc tttaattcac
     8161 ctgatgaatc ggtttcattt tcatagttat agagttgaat atccatgtcc ccaaactgaa
     8221 aatgagcatc tccctgtgtg atgttttgaa taactgaaac acctttttct gaagcagtct
     8281 gtaaaacctt atcataaccg tacagattat cccatagacg ttcaaaatta gtaatacgat
     8341 tatcactata ttttttaaga tagactcggt caactggata ggtagacagt aattcatcaa
     8401 catttccaat atgatcactg tgggtatggg tcaccaaaat aaaatcaagt ttttggacac
     8461 ccaattcctt caaacgacga aagacacggt ctgttagaac atgcttataa gacgtttcaa
     8521 ttccttctct ccatggatag cgagaatcac ttccatctgg gaaatcataa tcttctcctg
     8581 tatccaccat ggcaaaatgt ccattgcttt caagaataat cgcatcactg ccaccttctt
     8641 gaacattgat aaagtggatt ttatttcctg aactttcttg agcctgaaca ttcccatacc
     8701 atgacaaacc taaaaaagcg cctacaagtg ctaaactagt taatttcttt ttcattctta
     8761 ctttctcaat ctctccaagg tttccttaaa aatctctggg atatctgctt taaattccaa
     8821 ggtcttacct gttctcggat gagtaaaacc taaagtcttg gcatgaagaa attgtccatg
     8881 tcctttcaaa gtcttgcgag gaccatagac ctcatcacca gcgactgaat ggccgatata
     8941 agccatgtgg acacggattt gatgagtgcg ccctgtctcc agttgcaact ctactaagct
     9001 ataatcgcca aagcgttcca agacgtgaaa acgcgtcact gcaggcttcc ctttagcagt
     9061 tacagcctgt ttcttacggt ctttttcact ccggccaatc ggcgcttcaa ttacaccacg
     9121 atcattaggc agatttccat gaacaatcgc ccaatatttg cggagagact ttttatcttt
     9181 gagttcttgg gcaagtacta gatgcgcatc atcgttttta gcaatcatga gaagacctga
     9241 cgtatcctta tcaatacggt gaacaatccc tggacgcaga accccattga tacccgacaa
     9301 gtccttaata tgatacatga gggcatttac tagggttcca ctggtatgac cagcactcgg
     9361 gtgcacaacc attccctgag gtttgttaac gacagccaca tcctcatctt ggtagactat
     9421 ttctagcgga agatcctcag ccacatactc taatacctct ggttctggca catggtaagt
     9481 gacgacatca ccctcttgga ctgtgtattt agctttcttg acttgaccat tgaccaagac
     9541 ctggcctgat ttaatttgtt cattcgcgag actacgtgat aattctgaca aatctgacaa
     9601 agccttatcc aaacgcagac caccagtttc aattttaatt tccatttatt tcctctttta
     9661 gcattgcaat caataaaata atcactccaa ccgtcagata gctatctgcc acattgaaaa
     9721 ttgcaaagtt gataaagtca aggtggaaca tatccacaac aaagccctga ctgaccctgt
     9781 caataaagtt tccaagacca cccgcgatta ttagagtcaa acccaagacc atccagaatg
     9841 agtcctccat gtgtttatgt aaataccaaa tggcacctat cacgacaacc agagtaatga
     9901 cagcgaataa cagctgctga tcttgtaaga tagaaaaggc tgcacctcga ttttgcaggt
     9961 aggtcaagct aacgaaattg ggaatccagg agcgcacttc acccagtgga atctgctgga
    10021 cgatatagga tttgaccaac tgatccagcc caattaaaag cagtacaatg actgccacta
    10081 ttgctctttt tttcatgatt tcctcttttg atcaaaatat tcttgcatga cttctacgaa
    10141 gagagtccca gcttgactaa gctccacttc ttcacgttta acatagacca tgcggttatc
    10201 taggttatcc ttgagacgaa taactgtaat gccattaaca ctgtcactat ctaaaaatcc
    10261 agaacctgtc gcataggcgt ccgtccgctc caaaatacca ttcaaggtgg cacggtctgt
    10321 cacattaaac atctgtgagc tagcgctggt atcgacaaag ttctctgaat aataaaggta
    10381 ctcgtctttc tcttgagtga aacgaaccgt tggtaaatcc gctaaatcct ccatgactaa
    10441 ttcatctttc tgggctaaag gatgaccctc acggagataa atatgggtat ggaaaggaat
    10501 caattcgatg acctccagac ctaatttttc aacccgttgc ataatcccct ttttattttg
    10561 attgttgagg tagataatcc caatctcact atgcccttgc gccacttcat ctaatatttg
    10621 aacagtagtt gattcaaaaa tacggaagtt cttatagtca ggatagcgct ctgaaaaggc
    10681 cgtaatagtt ggtggcaaga agtcatagtg ctggctagca acggaaaatt catctttttc
    10741 ttcttcagga ttggcatact gattttgaaa aatatcaaat cctttaacca attcttgcgc
    10801 tttttcataa aattccatcc cacgacgggt caagaaagtc cctgagctgg tccgacggaa
    10861 aatcttaaaa cccaactctt tttccaaatc ccgaacagaa atagacagac tcggctgact
    10921 aacatacatc ttttcagcag cttcacggaa agtaccacta ttggcaatag ccacaacata
    10981 gcgtaattgt tgaatgttca tcttctaccc ctaacttctt tatcttttca ttataccata
    11041 ttttagaagt tttccaaaaa ggaaaaaaga acatcctatt cttcttaact atcttcacta
    11101 tctgcctttc tcaagccaac cttattttca aaatcaattc aaaaaaataa gtggctacac
    11161 accactacaa tatcgaaaag aaaaacgttg actatttgtg aaaaaagaaa atgccggaaa
    11221 gttccgacat tattttagta agctaacttc ctgaaaatag gagcaaccac acatcccaga
    11281 aggcagtgat attaatgaga atatgaacta gtattggata gtagagattt ttagtcatgc
    11341 gatacaatag agctaaaata agacctccac tagcataaat gaaaaaagca agaggagtta
    11401 aagcaaaatt gatatgaata taaccgaaaa taatagcaga aagcaaaaca tctccgtacc
    11461 aaggcgagtt tttgaaaaag gttgtcataa tcacaccgcg ataaatcaat tcctcagcaa
    11521 taggggcgat gaagcaaacg atgagcaaga aataagggaa ctcctgtctc cccatcattt
    11581 ctaccgtttc attcaaagaa atctgatttg aagacaggga tatgaaatac gaaaagagga
    11641 agtcagacat atatgaaatg atgtagccca gtaaaaggta gatgaagtac ctcagctgcc
    11701 acttgaaatg aaaaattttc tttcctgcaa aaaccagtag atagatgacc gctaagaaaa
    11761 gaactccgct ctccatcaaa agcagaatct gaaaaaattc acgacttgct ggtagatagg
    11821 gctttgcgag gtgattgaaa actctccaaa accaagttga tttgtaaaaa attaaggaca
    11881 atgctagtaa aatttgaata gcccgttttt tcatattaaa ttctctgctt tctccacttg
    11941 tttcttcata ttactaataa attttactta aaatctcgca gcacttcctt tgcaaagatg
    12001 attgcctcct ccaatatatc ctaaatcata ggtgcctctg ggacaaaatc catgaaccgg
    12061 cagagttaat actggttcta tttcccaatc gtacctacca ttaggatttt taccatatgg
    12121 atctgctcca ccttgtatca gctctaattc ttcatttgtt agatttatat tttttgtcat
    12181 taaaatcatg atatatttcc tccattattc ttcagattag ttgagtaatc tgatactcat
    12241 acctacttac aaaaaaacta ttatattaag ttggtttttt aatttgtcta gttgcaacat
    12301 tgacaaacat agtatagcat atctttgcca aatatcctct tcaaatcatg aattgtcatc
    12361 aaaacatctt aaactataaa atcaattagt ctcaagcttt ctatcaattt cttctccaaa
    12421 atatgctata ataatagcaa aagataaaga aggaagacct atgattaaac tactagcctt
    12481 ggatatggat ggaaccctcc tcaatgaagc caaggaaatc ccacaggctc acatcgctgc
    12541 tattcaccaa gccattgaaa aaggtgtcaa actggttctc tgtacgggtc gccccctttt
    12601 cggtgtcctc ccctactaca aaaaactggg actcgacctc cagaatgagt atgtgattgt
    12661 taacaacggt tgttcaactc accagactag cgactggggc ttggttgact ggcaagaact
    12721 tagtccagct gacatcgaat acctctatga cattgctgaa aagagtgatg ttcagttgac
    12781 actttttgac gagtcacatt attttgttct cggtggcaaa cccaatcaag ttattgaaaa
    12841 tgatgctaaa ctagtatttt cagacctgac tgaaatttct cttgaagaag cgactagtgg
    12901 aaagttacgg atgttccaag gtatgttttt aggaacaaaa gaacaaacag acgattttga
    12961 gcagcgtttt gctgaagagc tttgccaacg attcagtgga gttcgttcgc agcctgtcat
    13021 ttatgaagca atgccgcttg gaacgacaaa ggctactgct ctttcacgac tagctgagat
    13081 tttgaagatt gattcctcag agattatggc catgggcgat gctaataacg atatcgaaat
    13141 gctccagttt gcagggcttg ggattgcaat gggaaatgcc agcgattatg tcaaatctct
    13201 tgcggatgcc gttacctcaa gcaacgaaga agacggcgtt gcgcgtgcta ttgagaaata
    13261 tattctataa aaaagaaaag caaatagaca gaagttactg ctatttgctt ttttgctaat
    13321 attttaaaat acggactaat caatagacaa gaatagcgaa tcataaaaat cgatttacta
    13381 gatgccatag tatcttatag ttgctaataa gaagttagtc tagcagaatg aatctctcat
    13441 ttctcccaca ctaatctgta atttgtctat acatttctgg tcttctatct cgaaacaagc
    13501 cccagtttag gcgttcactt gctcccttgt ctaggtcata agtagctaac agaacagctt
    13561 cttcttgtct ttcagctcgt tctagaatag ctcctgtttc atccgtcata aaggaggaac
    13621 cgtagaagtc aagactggaa ctctgtccgc cattttcctc actaggagta acctcctcta
    13681 aaccataacg attggctgcg atgactggaa caatattcgc tgctgcgtgc ccttgcatag
    13741 tacgttgcca gtgaccacaa ctatctgtat ccaaaatcgg ctctgaaccg atggctgttg
    13801 gataaaagag caattctgcc ccattcagaa caagacagcg ggctgtttcg gggaaccatt
    13861 gatcccaaca gataccgata ccaatcttag catagcgagt attccagacc ttgaaaccag
    13921 tgttaccagg cgtgaaatag aatttttctt gataataatg gtcatctggt atgtgggtct
    13981 ttcgataaac gcccagcact tccccatctg catcaatgac ggcaatagag ttatacaaga
    14041 cattaccatc tttttcatag aaactgattg gtaaaacaac ttgtagttcc ttagcaatca
    14101 ccttaaaatg ctgaatggca gtattttccg ctacagattg ggcatactgg tagtagtcat
    14161 actgacgttc ctgacagaaa tagggatgtt caaacaactc gggcaagaga ataatttggg
    14221 ctccttgctc agcagcctga cgtactaaac gctctgcggt ttggatattt gttgccacat
    14281 ccttagcgca ttgcatctga atggttgcaa ctcttacatt tctcatcttt ttctcctatt
    14341 ctggaatttg ttgggtgata cagtggatat tgccaccacc taagagaata tctctggctg
    14401 gtattccgac aactttacgg tctgggaaac acttgctgag gatatctaag gccacttggt
    14461 cgtttacatc ctcaaactgt ggaaccaaga cagccttgtt ggcgatataa aagtttacgt
    14521 aggaagctgc tagtcgttca cctgcgtatc gcttttcttc tccttcttca tagatgtagc
    14581 ctggcaaatc ttcttctgtc acaacttgtc gaactgcagg gataggcaat ttatgaatgg
    14641 tgaagtgaca accttttgca tctgtttcct gttctaagag ttcgagatct gcttttgaca
    14701 tggcatactg gggatcattt tcgtcatctg tccaagccaa aacaagctca gcaggaccaa
    14761 caaaggcagc aacattatcg acgtgttcat tggtttcatc ctgataaata ccataaggaa
    14821 gccaaataac tttttcagca ccaagacttt ctaataatgt gttttcaatc tcctctttag
    14881 tcaggttagg attgcgacca ggactaagca agcaactttc agttacgaga atagttcctt
    14941 gaccatcgct atggattgcg cctccttcca gtacaaaagg tttagcatca tagacaggcc
    15001 tttccaaggc ctcagcaaaa cgactggcta cttggtcatc ctcttcataa tcttgataaa
    15061 gaccatcata ggtgcctccc caagcattga aggcccaatc cacggctaat ttcttacctt
    15121 tatcattgac gagaatggtt gggccagtat cacgcgccca ggcatcattg gtgggaatgt
    15181 ctaaataaac aaccttgtct ccaagatagg attgggcttc agatagatag gcctgctcca
    15241 ccaaaagata gactctttcc ccttctgcta tggtctcgat gatctgagta aatgctcttt
    15301 tagcagcctt tccttgaaaa ggccatgatc ctggtcgagt cggccatatc atgagggtac
    15361 catgatgggg ttcgtactct gctggcatgt gatagcctaa tttttttgga ctgtccatca
    15421 tgataatctc cctttaaagt cttgatagcc aaaagctttg agtaagctac agtctccctg
    15481 ttcgtccatg agatagagac ttggcaatcc aataccatta aaggtattat ttttgacaaa
    15541 agaataaatg gccatgtctt gaaaataaag tctgtctccg atttggactg gattttcaaa
    15601 actataatca ccaatcacat cgcccgtcag acaggtatta gaagaaagtc tgtaggtatg
    15661 ggctttttcc tgtgcctcaa agccatttct caaagatgga cgatagggca tctcaagtac
    15721 atcaggcata tggcaggtcg cagaggcgtc taaaaccaag atttccatac cgttttctac
    15781 aatatctaat acctcagttg ctaaataacc cgcattaagc gcaatggctt caccaggctc
    15841 gatatagatt tcaagattgt aagtttttcg gatacgcttg atttctgaaa tcagcaaatc
    15901 cacatcgtaa ccttctcttg taatatgatg accaccaccc atattgagcc attttacctc
    15961 atgtaagtag ggaccaaact gttcttctac tgctttcaaa gttgtttgta aatcatctgc
    16021 tccctgctcg caaagggtat gaaaatgaag tccgtcaacc aaatctagca aatcactcgg
    16081 aatcttgtct atagtaactc caaagcgaga acctggtgca caagggtcat agagcgcgtg
    16141 atctccttga gttgaacact gagggttgag gcgcaaacca acactgacac cagcctctcg
    16201 acaacgcgga ccgtgtttac gcaactgtct ctctgagtta aagacgatat ggtccattat
    16261 ctctagcaat tcctccaagt ctgcatcctt gaaagcaggc gcaaatacat ggacttcacc
    16321 aggaaattct tcccttgcca atttggcctc atagagtcca ctagctgtcg tacctgatag
    16381 atactggcta atcaagggat aagttttgta gagggaatat gccttctggg caagcaagac
    16441 cttgcaaccg gcctcttctt gtacatattg tagaatgcgg caattagctt ctaacttgac
    16501 caagtcaata acataggctg gtgttggtac ttgttctaac ttcattagtc caccatttgt
    16561 ggattttcaa ccacaaccca tggcaaacca tactcattca aagcttccat gaatggatct
    16621 ggatctaact cctcaaggtt atacactcca gcttgtttcc aagttccgtt catgactaat
    16681 tttgtcccaa tcatggctgg aacgcctgtc gtgtatgaaa ttgcttgtga cccgacttct
    16741 gcatagcact cttgatggtc gcaaacattg tagatgtaga tagtcttttc aacgccatct
    16801 ttgacacctg taaagataca tccaatattg gtttttccga ctgtacgtgg cccaagactg
    16861 gcaggatctg gaagcaaggc tttcaaaaat tgaattggaa caatttcttg gccgttaaag
    16921 ttaatggtat ccgtacgaag gagtccaaca ttttcaagac atttcatgtg cgtcaagtaa
    16981 gattgaccaa aagtcataaa gaaacgaatg cgtttgacac ctggaatgtt cttggccaat
    17041 gattcgattt cttcatggtg aaggagatac atatcttttt gtccaacttg agggaaatca
    17101 tactcacgct tgatagacat agcttcgact tcgacccatt tcccatcttc ccagtaagaa
    17161 cctggcgcag aaacctcacg gagattaatt tctggattaa agttggttgc aaatggataa
    17221 ccgtggtcac cgccattaca gtctaaaatg tcgatataat ggatttcatc aaaatagtgt
    17281 ttgagggcat aagctgaaaa gacactagtt acacctgggt caaaaccaga accaagaaga
    17341 gcagtcaagc ctgcttcttt gaatttctct tgataagccc actgccatga gtagtcaaag
    17401 taggctgtaa aaccaagttc cttacaacgt ttttcgtaga tagcacgcca ctcagggtct
    17461 tctgtgtctt ctgcttcgta gttggctgta tcgatatagt gaacacctgt tgccaaacaa
    17521 gcatccataa tggttaaatc ttgataaggc agagctacat tcaaaacagc ttctggtttg
    17581 tagctttcaa tcaaggtaat gacctcttct accttgtcag catcaagtgc tgcagtttca
    17641 attttagtac ttgttttgcc ttctagcttc gctttcaagt catcgcattt tgacttggta
    17701 cggctagcaa tcataatctc tgtaaatgtt tcgctatctt gacaaatctt tgaaatagca
    17761 acttgggcaa cgcccccaca accaataact agtaaacgac tcattttttt ccttcctctt
    17821 cttctaaaat gtcctcaaca tacttgggca acataaaggc tcccacgtgt aagtttgcag
    17881 tgtagtattc tgtgaaaagc tggcgttttt tccagccttc cttgtcaaaa tctttgacag
    17941 ggtggtattt tttcgatgca aatccaaaca accaatagcc agctgggcta gttggaatat
    18001 gggcctgata aacccgactg attggaaagg cttgattgac cttgcggtgc atgcttcggc
    18061 aggccgactc atcctcgtca aagaagggac tcccatgctg gtaaatcatg atgccgtctt
    18121 ccttcagagc tcgataacta ttgccgtaga attccttggt aaagagtcct tccgtatggc
    18181 caaatggatc tgtcgcatcg ttgatgataa tatcgtaatc atcttcgcag tttcgcaaaa
    18241 agcgtagccc attttggtag taaatggtaa cacgaggatc atctagccct gcagcaaagt
    18301 ctgggaaata ctcacgacag acctcgacca acatctcatc cggttccacg atatcgattt
    18361 gttccagttc aggatagagt gttaatactt gggcaacacc gccgtcacca cccccaataa
    18421 ccaatacttt ctttggattt gggtggacag ccatgggaac gtggacggtc atttcattgt
    18481 agacgaaatc atccgcatct gagaacaaga catggccatt taaaatcagt attttcccaa
    18541 aagctggcgt atccaagact tcgatatcct gccattcact ttttccagcg taaagttgct
    18601 tggctgttct cagagacaat ttgacatctg gagtatgaac ttcagaaaac cataaatcca
    18661 tctatttctc cttatattat atttagcgca gttagctact gccaaagccc aagtggtata
    18721 cttggaataa gtcactgtgg attagttcat ttcctccaat cgcttgacga tttccgaaag
    18781 gctctaacca cagttttttg tttcaattgg taatgagttt gataacgcat agacgtttta
    18841 tctcgtctaa ggtaacaagg caaaaaattc gtggataacc aagtagactt gaaatactac
    18901 atctggaggt actcccatgc tttatgtggg cattgatgtc gctaaaaata aacacgatgt
    18961 tacagccttg aatgttccag gaaaaactgt tcttaaacca ctcacttttt caaataataa
    19021 agctggtttt gaactcttag atctgtctct tcgacaactc aaccaagact gtctcatcgc
    19081 tcttgaaaat accggacatt atgcctttaa tctactgaac ttcctgcatg aacaaggata
    19141 taaagtttac acctacaatc ctttgctcat caaggaattt gccaaatcat tatcacttcg
    19201 caagactaaa acggataaga aagacgctca tggcatcgct cttaaacttc tttctgaccc
    19261 caatcgtgaa caatttcaac acgataatcg gcaagtaga
//
LOCUS       DBEJAU010000043        19071 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC323 isolate 683620
            SAMN38261939-rid24807223.denovo.043, whole genome shotgun sequence.
ACCESSION   DBEJAU010000043 DBEJAU010000000
VERSION     DBEJAU010000043.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261939
            Sequence Read Archive: SRR26833919
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 19071)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 19071)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576303.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576303.1
            Genome Coverage       :: 154x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/19/2025 01:05:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,121
            CDSs (total)                      :: 2,078
            Genes (coding)                    :: 1,943
            CDSs (with protein)               :: 1,943
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 36
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 72 of 135
            Pseudo Genes (incomplete)         :: 63 of 135
            Pseudo Genes (internal stop)      :: 51 of 135
            Pseudo Genes (multiple problems)  :: 46 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..19071
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261939-rid24807223.denovo.043"
                     /strain="GPSC323"
                     /isolate="683620"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            complement(<1..374)
                     /locus_tag="ACL29Z_001588"
     CDS             complement(<1..374)
                     /locus_tag="ACL29Z_001588"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000700388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal-type histidine triad protein"
                     /protein_id="HGR0069869.1"
                     /translation="MKINKKYLAGSVAVLALSVCSYELGRYQAGQDKKESNRVAYIDG
                     DQAGQKAENLTPDEVSKREGINAEQIVIKITDQGYVTSHGDHYHYYNGKVPYDAIISE
                     ELLMKDPNYQLKDSDIVNEIKGG"
     gene            complement(532..2982)
                     /gene="phtA"
                     /locus_tag="ACL29Z_001589"
     CDS             complement(532..2982)
                     /gene="phtA"
                     /locus_tag="ACL29Z_001589"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000700436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal histidine triad protein PhtA"
                     /protein_id="HGR0069870.1"
                     /translation="MKINKKYLVGSAAALILSVCSYELGLYQARTVKENNRVSYIDGK
                     QATQKTENLTPDEVSKREGINAEQIVIKITDQGYVTSHGDHYHYYNGKVPYDAIFSEE
                     LLMKDPNYKLKDEDIVNEVKGGYVIKVDGKYYVYLKDAAHADNVRTKEEINRQKQEHS
                     QHREGGTPRNDGAVALARSQGRYTTDDGYIFNASDIIEDTGDAYIVPHGDHYHYIPKN
                     ELSASELAAAEAFLSGRGNLSNSRTYRRQNSDNTSRTNWVPSVSNPGTTNTNTSNNSN
                     TNSQTSQSNDIDSLLKQLYKLPLSQRHVESDGLVFDPAQITSRTARGVAVPHGDHYHF
                     IPYSQMSELEERIARIIPLRYRSNHWVPDSRPEQPSPQPTPEPSPGPQPAPNLKIDSN
                     SSLVSQLVRKVGEGYVFEEKGISRYVFAKDLPSETVKNLESKLSKQESVSHTLTAKKE
                     NVAPRDQEFYDKAYNLLTEAHKALFENKGRNSDFQALDKLLERLNDESTNKEKLVDDL
                     LAFLAPITHPERLGKPNSQIEYTEDEVRIAQLADKYTTSDGYIFDEHDIISDEGDAYV
                     TPHMGHSHWIGKDSLSDKEKVAAQAYTKEKGILPPSPDADVKANPTGDSAAAIYNRVK
                     GEKRIPLVRLPYMVEHTVEVKNGNLIIPHKDHYHNIKFAWFDDHTYKAPNGYTLEDLF
                     ATIKYYVEHPDERPHSNDGWGNASEHVLGKKDHSEDPNKNFKADEEPVEETPAEPEVP
                     QVETEKVEAQLKEAEVLLAKVTDSSLKANATETLAGLRNNLTLQIMDNNSIMAEAEKL
                     LALLKGSNPSSVSKEKIN"
     gene            complement(3236..4969)
                     /gene="ptsP"
                     /locus_tag="ACL29Z_001590"
     CDS             complement(3236..4969)
                     /gene="ptsP"
                     /locus_tag="ACL29Z_001590"
                     /EC_number="2.7.3.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014294264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008965 - phosphoenolpyruvate-protein
                     phosphotransferase activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoenolpyruvate--protein phosphotransferase"
                     /protein_id="HGR0069871.1"
                     /translation="MTEMLKGIAASDGVAVAKAYLLVQPDLSFETITVEDTNAEEARL
                     DAALQASQDELSVIREKAVGTLGEEAAQVFDAHLMVLADPEMISQIKETIRAKKVNAE
                     AGLKEVTDMFITIFEGMEDNPYMQERAADIRDVTKRVLANLLGKKLPNPASINEEVIV
                     IAHDLTPSDTAQLDKNFVKAFVTNIGGRTSHSAIMARTLEIAAVLGTNNITEIVKDGD
                     ILAVNGITGEVIINPTDEQAAEFKAAGEAYAKQKAEWALLKDAQTVTADGKHFELAAN
                     IGTPKDVEGVNNNGAEAVGLYRTEFLYMDSQDFPTEDEQYEAYKAVLEGMNGKPVVVR
                     TMDIGGDKELPYFDMPHEMNPFLGFRALRISISETGDAMFRTQIRALLRASVHGQLRI
                     MFPMVALLKEFRAAKAVFDEEKANLLAEGVAVADNIQVGIMIEIPAAAMLADQFAKEV
                     DFFSIGTNDLIQYTMAADRMNEQVSYLYQPYNPSILRLINNVIKAAHAEGKWAGMCGE
                     MAGDQQAVPLLVGMGLDEFSMSATSVLRTRSLMKKLDTAKMEEYANRALTECSTMEEV
                     LELQKEYVNFD"
     gene            complement(4975..5238)
                     /locus_tag="ACL29Z_001591"
     CDS             complement(4975..5238)
                     /locus_tag="ACL29Z_001591"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019775469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphocarrier protein HPr"
                     /protein_id="HGR0069872.1"
                     /translation="MASKDFHVVAETGIHARPATLLVQTASKFASDITLEYKGKSVNL
                     KSIMGVMSLGVGQGADVTISAEGADADDAIAAISETMEKEGLA"
     gene            5589..5807
                     /gene="nrdH"
                     /locus_tag="ACL29Z_001592"
     CDS             5589..5807
                     /gene="nrdH"
                     /locus_tag="ACL29Z_001592"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000259243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0045454 - cell redox homeostasis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutaredoxin-like protein NrdH"
                     /protein_id="HGR0069873.1"
                     /translation="MVTVYSKNNCVQCKMTKRFLDSNNVSYREINLDEQPEYVDQVKE
                     LGFSAAPVIQTPTEVFSGFQPGKLKQLA"
     gene            5888..8047
                     /gene="nrdE"
                     /locus_tag="ACL29Z_001593"
     CDS             5888..8047
                     /gene="nrdE"
                     /locus_tag="ACL29Z_001593"
                     /EC_number="1.17.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000523276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004748 - ribonucleoside-diphosphate
                     reductase activity, thioredoxin disulfide as acceptor
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="class 1b ribonucleoside-diphosphate reductase
                     subunit alpha"
                     /protein_id="HGR0069874.1"
                     /translation="MGLKHLEDVTYFRLNNEINRPVNGQIMLHKDKEALDAFFKENVV
                     PNTMVFDSIKDKINYLIEHNYIETAFIKKYRPEFLEELAQFIKDQNFQFKSFMAAYKF
                     YNQYALKTNDGEYYLENMEDRVFFNALYFADGNEAVAIDIANEIIHQRYQPATPSFLN
                     AGRARRGELVSCFLIQVTDDMNSIGRSINSALQLSRIGGGVGITLSNLREAGAPIKGY
                     EGAASGVVPVMKLFEDSFSYSNQLGQRQGAGVVYLNVFHPDIIAFLSTKKENADEKVR
                     VKTLSLGVVVPDKFYELARKNEEMYLFSPYSVEKEYGVPFNYIDITEKYDELVANPNI
                     RKTKIKARDLETEISKLQQESGYPYVVNIDTANRANPVDGKIIMSNLCSEILQVQEPS
                     LINDAQEFLQMGTDVSCNLGSTNVVNMMTSPDFGRSIRAMVRALTFVTDSSHIVAVPT
                     IDHGNSQAHTFGLGAMGLHSYLAQQLIEYGSPESVEFTSIYFMLMNYWTLVESNNIAR
                     ERGITFHNFEKSDYANGSYFDKYVTGEFVPTSDRVKELFKNVFIPGVADWAELRDKVQ
                     EDGLYHQNRLAVAPNGSISYINDVSASIHPITQRIEERQEKKIGKIYYPAAGLSTETI
                     PYYTSAYDMDMRKVIDVYAAATEHVDQGLSLTLFMRSDIPKGLYEWKRENKQTTRDLS
                     ILRNYAFNKGIKSIYYVRTFTDDGGEVGANQCESCVI"
     gene            8235..9197
                     /gene="nrdF"
                     /locus_tag="ACL29Z_001594"
     CDS             8235..9197
                     /gene="nrdF"
                     /locus_tag="ACL29Z_001594"
                     /EC_number="1.17.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004253599.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005971 - ribonucleoside-diphosphate
                     reductase complex [Evidence IEA];
                     GO_function: GO:0004748 - ribonucleoside-diphosphate
                     reductase activity, thioredoxin disulfide as acceptor
                     [Evidence IEA];
                     GO_process: GO:0009263 - deoxyribonucleotide biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="class 1b ribonucleoside-diphosphate reductase
                     subunit beta"
                     /protein_id="HGR0069875.1"
                     /translation="METYYKAINWNAIEDVIDKSTWEKLTEQFWLDTRIPLSNDLDDW
                     RKLSNKEKDLVGKVFGGLTLLDTMQSETGVQALRADIRTPHEEAVFNNIQFMESVHAK
                     SYSSIFSTLNTKAEIEEIFEWTNTNPYLQKKAEIVNEIYLNGSPLEKKVASVFLETFL
                     FYSGFFTPLYYLGNNKLANVAEIIKLIIRDESVHGTYIGYKFQLGFNELPEEEQEKLK
                     EWMYDLLYTLYENEEGYTESLYDGVGWTEEVKTFLRYNANKALMNMGQDPLFPDSAED
                     VNPIVMNGISTGTSNHDFFSQVGNGYLLGEVEAMQDDDYNYGLD"
     gene            9379..10140
                     /locus_tag="ACL29Z_001595"
     CDS             9379..10140
                     /locus_tag="ACL29Z_001595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000917571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR family DNA-binding transcription
                     regulator"
                     /protein_id="HGR0069876.1"
                     /translation="MLKQEKLTKILEIVNSKGTITVKQIMDEIAVSDMTARRYLQELA
                     DKDLLIRVHGGAEKLRTNSLLTNERSNIEKQALQTAEKQEIAHFAGSLVEERETIFIG
                     PGTTLEFFARELPIDNIRVVTNSLPVFLILSERKLTDLILIGGNYRDITGAFVGTLTL
                     QNLSNLQFSKAFVSCNGIQNGALATFSEEEGEAQRIALNNSNKKYLLADHSKFNKFDF
                     YTFYNISNLDTIVSDSKLSDSILFKLSKHIKVIKP"
     gene            complement(10425..10676)
                     /locus_tag="ACL29Z_001596"
     CDS             complement(10425..10676)
                     /locus_tag="ACL29Z_001596"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000471577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3884 family protein"
                     /protein_id="HGR0069877.1"
                     /translation="MFKDFIQSIYEKVYIINFEKCSQIPCLTSEELKSLGKWYVSTGK
                     EWICHSDADLEEFKNLFLNFINPEEWDTISFDSDFMPFQ"
     gene            complement(10719..12125)
                     /gene="lacG"
                     /locus_tag="ACL29Z_001597"
     CDS             complement(10719..12125)
                     /gene="lacG"
                     /locus_tag="ACL29Z_001597"
                     /EC_number="3.2.1.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864138.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0033920 - 6-phospho-beta-galactosidase
                     activity [Evidence IEA];
                     GO_process: GO:0019512 - lactose catabolic process via
                     tagatose-6-phosphate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-galactosidase"
                     /protein_id="HGR0069878.1"
                     /translation="MTKTLPKDFIFGGATAAYQAEGATHTDGKGPVAWDKYLEDNYWY
                     TAEPASDFYNRYPVDLKLAEEYGVNGIRISIAWSRIFPTGYGQVNAKGVEFYHNLFAE
                     CHKRHVEPFVTLHHFDTPEALHSNGDFLNRENIEHFVDYAAFCFEEFPEVNYWTTFNE
                     IGPIGDGQYLVGKFPPGIQYDLAKVFQSHHNMMVSHARAVKLYKEKGYKGEIGVVHAL
                     PTKYPLDPENPADVRAAELEDIIHNKFILDATYLGRYSAETMEGVNHILLVNGGSLDL
                     REEDFTALEAAKDLNDFLGINYYMSDWMEAFDGETEIIHNGKGEKGSSKYQIKGVGRR
                     VAPDYVPRTDWDWIIYPQGLYDQIMRVKKDYPNYKKIYITENGLGYKDEFVDNTVYDD
                     GRIDYVKQHLEILSDAIADGANVKGYFIWSLMDVFSWSNGYEKRYGLFYVDFETQERY
                     PKKSAHWYKKVAETQIID"
     gene            complement(12340..14034)
                     /locus_tag="ACL29Z_001598"
     CDS             complement(12340..14034)
                     /locus_tag="ACL29Z_001598"
                     /EC_number="2.7.1.207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001037357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_component: GO:0019197 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase complex [Evidence IEA];
                     GO_function: GO:0015155 - lactose transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="lactose-specific PTS transporter subunit EIIC"
                     /protein_id="HGR0069879.1"
                     /translation="MDKLIIFIEKGKPFFEKLSRNIYLRAIKDGFISSMPAVLFSSIF
                     ILIAAVPNIFGFKWSDEQLAFILKPYNYSMGILALLVAGTTAKSLTDSVNTRSMEKTN
                     QINYMSTFLAAVVGLLILAADPIEGGFANGLLGTRGLLTAFLAAFITVNIYKVCIKNN
                     VTIRLPEEVPPNIAQVFKDVIPFALSVLSIYGLDLIVRNIFGTNVAESVGKILAPLFS
                     ATDGYIGLAIVFGAYAFFWFVGIHGPSVVEPLIVAISYANIEANVQLVQAGMHADKIL
                     NPVTQTFVVTMGGTGATLVVPFMFMWLCKSKRNRIVGRASVVPTFFGVNEPILFGAPI
                     VLNPIFFIPFVTAPIINVWIMKFFVDVLQMNSFSIILPWTTPAPIGIVMGTALAPLSF
                     VLAITLIIIDTLIYYPFVKVYDHQILEEERKGNSSSELKEKVAANFNTVKADAILEKA
                     GVDAAQNTITEETNVLVLCAGGGTSGLLANALNKAAAEYNVPVKATAGGYGAHREMLP
                     EFDLVILAPQVASNFEDMKAETDKLGIKLAKTEGAQYIKLTRDGKGALAFVQEQFD"
     gene            complement(14036..14353)
                     /locus_tag="ACL29Z_001599"
     CDS             complement(14036..14353)
                     /locus_tag="ACL29Z_001599"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HGR0069880.1"
                     /translation="MNREEVTLLGFEIVAYAGDARSKLLEALKAAEAGDFEKADALVE
                     EAGSCIAEAHHAQTSLLTKEASGEDLAYSVTMMHGQDHLMTTILLKDLMHHLIELYKR
                     GVK"
     gene            complement(14389..15225)
                     /locus_tag="ACL29Z_001600"
     CDS             complement(14389..15225)
                     /locus_tag="ACL29Z_001600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000285719.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HGR0069881.1"
                     /translation="MYRILNPMNHNVSLVRNDKGEEVIVIGKGIAFGKKKGDLIAENQ
                     VEKIFRMKTEESRENFMALLKDVPLDFITVTYEIIDKLSKKYHYPIQEYLYVTLTDHI
                     YCSYQALTQGRYKDSNLPDISAKYPVAFQIANEAFEIYRQKLADHFPEDEIIRIAYHF
                     INAEGENEVELVESIDKRKEILRNVEEVLTDYAIQRTKKNNHFYDRFMIHLNYFLDYL
                     DRSRDDNQSLLDMEDHIKQSYPKAFEIGSKIYDVITQHTGLDLYKSERVYLVLHIQRL
                     LS"
     gene            complement(15459..16439)
                     /gene="lacD"
                     /locus_tag="ACL29Z_001601"
     CDS             complement(15459..16439)
                     /gene="lacD"
                     /locus_tag="ACL29Z_001601"
                     /EC_number="4.1.2.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001229146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009025 - tagatose-bisphosphate aldolase
                     activity [Evidence IEA];
                     GO_process: GO:0019512 - lactose catabolic process via
                     tagatose-6-phosphate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tagatose-bisphosphate aldolase"
                     /protein_id="HGR0069882.1"
                     /translation="MALTEQKRVRLEKLSDENGIISALAFDQRGALKRLMAQHQTEEP
                     TVAQMEELKVLVADELTKYASSMLLDPEYGLPATKALDEKAGLLLAYEKTGYDTTSTK
                     RLPDCLDVWSAKRIKEEGADAVKFLLYYDVDSSDELNQEKQAYIERIGSECVAEDIPF
                     FLEILAYDEKIADAGSVEYAKVKPHKVIGAMKVFSDPRFNIDVLKVEVPVNIKYVEGF
                     AEGEVVYTREEAAAFFKAQDEATNLPYIYLSAGVSAKLFQDTLVFAHESGANFNGVLC
                     GRATWAGSVEAYIKDGEAAAREWLRTTGFENIDELNKVLQTTATSWKERV"
     gene            complement(16441..17370)
                     /locus_tag="ACL29Z_001602"
     CDS             complement(16441..17370)
                     /locus_tag="ACL29Z_001602"
                     /EC_number="2.7.1.144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000604270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009024 - tagatose-6-phosphate kinase
                     activity [Evidence IEA];
                     GO_process: GO:0019512 - lactose catabolic process via
                     tagatose-6-phosphate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tagatose-6-phosphate kinase"
                     /protein_id="HGR0069883.1"
                     /translation="MILTVTMNPSIDISYPLDELKIDTVNRVVDVTKTAGGKGLNVTR
                     VLSEFGDSVLATGLVGGKLGEFLVEHIDDQVKKDFFSIQGETRNCIAILHGDNQTEVL
                     EKGPEVLEQEGQDFLEHFKKLLESVEVVAISGSLPAGLPVDYYASLVELANQAGKLVV
                     LDCSGAALQAVLESPHKPTVIKPNNEELSQLLGREVSEDLEELKEVLQESLFTGIEWI
                     IVSLGANGTFAKHGDTFYKVDIPRIQVVNPVGSGDSTVAGISSGLLHKESDAGLLIKA
                     NVLGMLNAQEKMTGHVNMANYQALYDQLIVKEV"
     gene            complement(17381..17896)
                     /gene="lacB"
                     /locus_tag="ACL29Z_001603"
     CDS             complement(17381..17896)
                     /gene="lacB"
                     /locus_tag="ACL29Z_001603"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002994294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose-6-phosphate isomerase subunit LacB"
                     /protein_id="HGR0069884.1"
                     /translation="MRIAIGCDHIVTDEKMAVSEFLKSKGYEVIDFGTYDHTRTHYPI
                     FGKKVGEAVTSGQADLGVCICGTGVGINNAVNKVPGVRSALVRDMTTALYAKEQLNAN
                     VIGFGGKITGELLMCDIIEAFIHAEYKPSEENKKLIAKIEHLESHNAQQTDANFFTEF
                     LEKWDRGEYHD"
     gene            complement(17927..18352)
                     /gene="lacA"
                     /locus_tag="ACL29Z_001604"
     CDS             complement(17927..18352)
                     /gene="lacA"
                     /locus_tag="ACL29Z_001604"
                     /EC_number="5.3.1.26"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0050044 - galactose-6-phosphate isomerase
                     activity [Evidence IEA];
                     GO_process: GO:0019512 - lactose catabolic process via
                     tagatose-6-phosphate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="galactose-6-phosphate isomerase subunit LacA"
                     /protein_id="HGR0069885.1"
                     /translation="MSIVIGADAAGLRLKEVVKDFLEKENFHLVDVTAEGQDFVDVTL
                     AVAAEVNKEEQNLGIVIDAYGAGPFMVATKIKGMVAAEVSDERSAYMTRGHNNSRMIT
                     MGAQLVGDELAKNIAKGFVNGKYDGGRHQIRVDMLNKMG"
     gene            complement(18509..19006)
                     /locus_tag="ACL29Z_001605"
                     /pseudo
     CDS             complement(18509..19006)
                     /locus_tag="ACL29Z_001605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000234238.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="aldose 1-epimerase family protein"
BASE COUNT         5676 a         3937 c         3377 g         6081 t
ORIGIN      
        1 ccacccttga tttcattgac aatgtctgaa tccttcaact gataattcgg atctttcatg
       61 aggagctctt cactgatgat ggcatcataa ggaaccttgc cattatagta atgataatgg
      121 tctccatgag aggtcacata accttgatcc gtaatcttga taacaatttg ttcggcgttg
      181 atcccctccc tcttactgac ttcatctggt gtcaagtttt ctgccttttg accagcctga
      241 tcaccatcta tataagcaac tcgattagac tctttcttat cctgaccagc ttggtaacgt
      301 ccaagctcat aggaacaaac acttagggca aggactgcca ctgaacctgc tagatatttt
      361 ttattgattt tcattctttc ctcttttctt aagtatattt gattcactat aaagtaataa
      421 accggttaat taactagtta atagtttact ctttttaata ttgcttgtca agaattttac
      481 atatatacat aataaaaatg aaagcctctt tatcgagact ttcatttttc attagtttat
      541 tttttcctta cttacagatg aaggattact tccttttaac aacgcaagta atttttctgc
      601 ttctgccatg atactattgt tatccataat ttgaagagtc aaattatttc gtaaaccagc
      661 tagagtttct gttgcattgg ctttcagact agaatccgtt actttcgcaa gcaaaacttc
      721 tgcttctttg agttgggctt ctactttttc agtctctact tgagggactt ctggctcagc
      781 aggtgtttcc tctactggct cttcatccgc tttgaagttc ttatttggat cttcactgtg
      841 gtctttcttg cctaacacat gctcactggc attgccccat ccatcattag aatgtggacg
      901 ttcgtcaggg tgttctacgt agtacttaat cgtcgcaaac aaatcttcca aggtatagcc
      961 atttggagct ttgtatgtgt gatcatcaaa ccaagcaaat ttaatgttat ggtaatgatc
     1021 cttatgagga ataatcaaat taccgttttt aacctcaact gtatgctcaa ccatatatgg
     1081 aagtcgaacg agtggaattc gtttttcccc tttcacacga ttgtaaatag ctgctgcact
     1141 atctccagtt ggatttgctt taacatctgc gtctggagat ggaggtagga tacctttttc
     1201 tttagtatag gcttgagctg caactttttc cttatcagaa aggctgtctt ttccaatcca
     1261 gtgactatgg cccatatgag gcgttacata tgcatctcct tcatcactga ttatatcatg
     1321 ttcatcaaaa atataaccat ctgacgttgt atacttatca gctaattgag caatacgaac
     1381 ttcgtcttca gtatactcaa tttgagaatt tggcttgcca agtcgctctg gatgggtaat
     1441 tggtgctagg aatgccaata aatcatctac caatttttct ttattagtcg attcatcatt
     1501 caagcgttct aataatttgt ctaaggcttg gaaatcagaa ttacgaccct tattttcaaa
     1561 caaggcttta tgagcctcag ttaacagatt atatgcttta tcataaaatt cttggtcacg
     1621 aggagcaaca ttttcttttt tagcagttaa agtgtgtgaa acactctctt gttttgataa
     1681 cttgctttca agatttttaa cagtttcaga tggtaaatct ttcgcaaaga cataacgaga
     1741 gatgcccttt tcttcgaata catatccttc cccaactttt cgtaccagct gactaaccaa
     1801 agaagaattt gagtctattt taagatttgg tgcaggttgc gggcctggac taggttccgg
     1861 agtcggttgt ggacttggtt gttctggcct tgaatctggt acccaatggt ttgaacgata
     1921 acgaagggga ataatacgag cgattcgttc ttccaattca gacatttgag agtaagggat
     1981 gaagtggtaa tgatctccgt gtggcactgc aacacctcta gctgttcgac ttgtgatttg
     2041 cgctgggtcg aaaacaaggc catcagattc tacatgtcgt tgactcaaag gcagtttgta
     2101 gagctgtttc aagagactat caatgtcatt actttgactt gtttgactgt tagtgttgct
     2161 gttgttgctt gtgttagtat ttgtagttcc tggattgctt acagaaggta cccagtttgt
     2221 tcttgaagtg ttatcgctat tttgtcggcg ataggttctt gaatttgaca gatttccccg
     2281 accagatagg aaggcttctg cagcagccaa ctcgctagct gataactcat tcttaggaat
     2341 gtaatggtaa tgatctccat gaggaacgat ataagcatca ccagtatcct ctatgatatc
     2401 agaagcatta aagatataac catcatctgt agtatagcgt ccttgcgaac gtgccaaggc
     2461 aacagcacca tcgtttcttg gagtcccacc ttcacgatgt tgactatgtt cttgtttttg
     2521 tcgattgatt tcctcttttg tacggacgtt atccgcgtgg gcagcatcct taaggtaaac
     2581 atagtatttt ccatctacct tgataacata tccacccttg acctcattaa caatatcctc
     2641 atcttttagc ttatagttcg gatctttcat gagtaattct tcactgaaaa tcgcatcata
     2701 aggaacctta ccattgtaat aatgatagtg gtcgccatgt gaagtgacat agccttggtc
     2761 tgttatcttg atgacgattt gctcagcatt gattccttca cgcttgctaa cctcatcagg
     2821 agtcaaattc tccgtttttt gcgtcgcttg ttttccatct atataggaaa cacgattatt
     2881 ttccttaacc gttctagctt gatacagtcc caactcgtaa gaacaaacac ttaaaatcaa
     2941 agctgccgca gaaccaacaa ggtatttctt attaattttc atcgaaactc tctttctatt
     3001 tgatatttct agttgcaatt catttctaaa ttgcagaaac tcctctctat tacttaactg
     3061 gttaatagtt tactcctaaa tctccaactt gtcaagaatt ttatgaacca tttaagtatt
     3121 ttttgttctg actactactt tttcaaggtt ggactttcta taagaaagat tttcttgaaa
     3181 attcttttta aaatatcaaa aaaatccctg taactgagtt gcagggactt ttcgattaat
     3241 caaaattaac gtattctttt tgaagttcaa gaacttcttc cattgttgag cattctgtaa
     3301 gggcacggtt tgcgtactct tccatcttag ctgtgtcgag tttcttcatc aagctgcgtg
     3361 tacgaagtac agatgttgct gacatagaga actcatccaa gcccattccg acaagaagtg
     3421 gaacagcttg ttggtcacca gccatctcac cacacatacc agcccattta ccttcagcgt
     3481 gagctgcttt gatcacattg ttaatcaagc gtaggattga tgggttgtat ggttggtaaa
     3541 ggtatgaaac ttgttcgttc atacggtctg ctgccattgt atattggatc aagtcgtttg
     3601 taccaattga gaagaagtca acttctttag caaattggtc tgcaagcata gccgctgcag
     3661 gaatctcgat catgatacca acttggatgt tatccgcaac tgcaacacct tcagcaagaa
     3721 ggtttgcttt ttcttcatca aagactgctt tcgctgcacg gaattctttc aagagcgcaa
     3781 ccattgggaa catgatacgc aattgaccgt gaacagacgc acgaagaaga gcacggattt
     3841 gtgtgcggaa catagcatct ccagtctcag agatagagat acgaagagca cggaatccaa
     3901 ggaatgggtt catttcgtga ggcatatcga agtaaggaag ttccttatct ccaccgatat
     3961 ccattgtacg aacgacaaca ggtttaccgt tcattccttc aagaacagcc ttgtatgctt
     4021 catactgctc atcttcagtt gggaagtctt gagaatccat gtacaagaac tctgtacggt
     4081 aaagtccaac agcttctgca ccgttgttgt taacaccttc aacgtctttt ggagtaccga
     4141 tattagcagc caactcgaag tgtttaccgt cagcagtcac tgtttgagca tctttcaaga
     4201 gcgcccattc agctttttgt ttcgcataag cttcaccagc tgctttaaat tctgccgctt
     4261 gttcatcagt tgggttgata ataacctcac cagtgatccc gttaacagca aggatgtcac
     4321 cgtctttaac gatttcagtg atgttgtttg tacctaatac agctgcaatt tcaagtgtac
     4381 gtgccatgat agctgagtgg cttgtacgtc caccgatgtt ggttacaaaa gcttttacaa
     4441 agtttttgtc caattgagct gtatcagatg gtgtcaagtc atgtgcaatc acaatcactt
     4501 cttcattgat agaagctggg tttggcaatt ttttaccaag aaggtttgcc aatacacgtt
     4561 ttgtcacatc gcggatatcc gctgcgcgtt cttgcatgta tgggttgtct tccatgcctt
     4621 caaagatagt gataaacata tctgtaactt ctttcagacc tgcttctgca ttcactttct
     4681 tcgcacggat agtttccttg atttggctga tcatttctgg gtcagcaaga accattaagt
     4741 gagcatcaaa aacttgagct gcttcttcac cgagcgtacc tactgctttc tcgcgaataa
     4801 cagaaagctc gtcttgtgat gcctgtagag cggcatcaag gcgagcttct tctgcgtttg
     4861 tatcttcgac tgtaatagtc tcaaatgaca aatccggctg aacgagtaga tatgcttttg
     4921 caactgcaac accgtcagat gctgcgattc ctttaagcat ttctgtcatt tcccttatgc
     4981 caatccttct ttttccattg tttctgagat tgcagcgata gcgtcatctg catctgcacc
     5041 ttcagctgag atagttacgt cagcaccttg gccaacacca agactcataa cacccataat
     5101 tgatttaagg ttaactgatt tacctttgta ctcaagagtg atatctgaag caaatttgct
     5161 agcagtttgt accaacaatg ttgctggacg tgcgtgaata cctgtttctg ccactacgtg
     5221 gaaatcttta gaagccatag tttgactctc cttttgttct ttcttttttt gagttatatg
     5281 tgataaccct tacaatttag tattatacca tcttctagga tttttttcaa gcattttctg
     5341 gattttcctt caatttcctt tcagataact tgctgaaaat cttctatcct agataacaaa
     5401 acacaggata tagtttcttt aaaaacaatt tataggataa tcattgctat ttcacaatac
     5461 aaacactata tattgtgttt atatataaaa acaacaaaag aacaccacta tatttagttc
     5521 aaatcattga caaaatttta ttttctgata tactaagata gtattaaatt ttgaagagga
     5581 gttacacaat ggtaaccgtt tattctaaaa acaattgtgt ccaatgtaaa atgaccaagc
     5641 gtttcttgga cagtaataat gtctcttatc gtgaaatcaa tcttgatgag caacctgagt
     5701 acgtcgatca agttaaagag ctcggtttta gcgcagctcc tgttatccaa acaccaactg
     5761 aagtcttttc aggtttccaa ccaggaaaac tgaaacaatt agcataatct tagtacatca
     5821 tccagaagaa actgctttta gggctaactt agaagccttt cttttgtaat tagataaggg
     5881 aaattttatg ggattaaaac atcttgaaga cgtgacttac ttccgtctta ataacgaaat
     5941 taaccgtcct gttaatggac aaatcatgct tcataaagat aaggaagcct tggatgcttt
     6001 ctttaaagaa aatgtagttc caaacactat ggtttttgat tcaatcaaag acaaaatcaa
     6061 ttacctcatt gaacacaact acatcgaaac agcctttatc aagaaatacc gtccagagtt
     6121 cttggaagaa ttggctcaat ttatcaaaga ccaaaacttc caattcaagt cattcatggc
     6181 agcttataaa ttttacaatc aatatgcctt aaagactaat gacggtgaat actatcttga
     6241 aaatatggaa gaccgtgtct tcttcaacgc cctttatttc gctgatggga atgaagctgt
     6301 tgcaatcgat attgccaatg aaatcatcca ccaacgctac caacctgcta ctccttcctt
     6361 cttgaatgct ggacgtgctc gtcgtgggga gttggtatct tgtttcctaa tccaagtgac
     6421 ggatgatatg aactctatcg gacgttctat caactcagct cttcaacttt cacgtattgg
     6481 tggtggtgtg ggaattaccc tcagcaacct tcgtgaagct ggtgcaccta tcaaaggcta
     6541 tgaaggagct gcttcaggtg tcgttcctgt tatgaagctt tttgaagaca gcttctctta
     6601 ctccaaccaa ttggggcaac gtcaaggtgc tggtgttgtc tacctcaacg tctttcaccc
     6661 agatatcatc gctttccttt caactaagaa agaaaacgct gatgaaaaag tacgtgtcaa
     6721 gactctatca cttggtgttg tagtacctga taaattctac gaattggctc gtaaaaatga
     6781 agaaatgtac ctcttcagcc cttactctgt agaaaaagaa tacggtgtgc cattcaatta
     6841 catcgacatt actgaaaaat acgatgaatt ggtcgcaaat ccaaatattc gcaagacaaa
     6901 aatcaaggcg cgggatttgg aaactgaaat ctctaaattg caacaagagt ctggctatcc
     6961 ttatgtagtc aacatcgata cggctaaccg tgcaaatcct gttgatggaa agattatcat
     7021 gagtaacttg tgctctgaga ttcttcaagt tcaagaacca agcttgatca acgatgctca
     7081 agaattcctt caaatgggaa cagatgtttc atgtaacctg ggttcaacca acgtggttaa
     7141 catgatgact tcacctgatt ttggtcgttc tatccgtgct atggttcgtg cccttacttt
     7201 cgttacagat agttcacata tcgtagctgt accaacgatt gaccatggaa atagccaagc
     7261 ccacaccttt ggtctcggtg ccatgggact gcacagctac cttgcccaac aactcattga
     7321 atatggttca cctgagtctg ttgaatttac aagcatctac tttatgctta tgaactactg
     7381 gaccttggta gagtcaaaca atattgcgcg tgaacgtggt attaccttcc acaactttga
     7441 aaaatcagac tatgctaacg gaagttactt tgacaagtat gtaactggtg aatttgttcc
     7501 aacatcagac cgtgttaaag aactcttcaa aaatgttttt atccctggtg ttgctgattg
     7561 ggctgaactt cgcgacaagg ttcaagaaga tggtctttac caccaaaatc gccttgctgt
     7621 agcgccaaat ggttctatca gctatatcaa cgacgtttct gcttctatcc acccgattac
     7681 gcaacgtatc gaagaacgcc aagagaagaa aattggtaaa atctactacc ctgctgctgg
     7741 cttgtctaca gaaaccattc cttactacac ttctgcctac gatatggata tgcgtaaagt
     7801 catcgatgtt tacgctgctg cgactgaaca cgtggatcaa ggactttcac tcaccctctt
     7861 catgcgtagt gacattccaa aaggccttta cgaatggaag agggaaaata aacaaacgac
     7921 acgtgacttg tccatccttc gtaactatgc ctttaacaag ggaatcaagt ctatctacta
     7981 cgtccgtacc tttacagatg acggtggaga agtcggcgcc aaccaatgtg aaagctgtgt
     8041 gatttagttt ctagcataga aacattattt ttccctaagc agcactgata aaatcaaatc
     8101 tactatgtca taacataatt tatgtaacat tttaaaagtc gggcttccga ctttttgtgc
     8161 gatactccta tagaattatg gtaaagtaga aataattgtg agttcgcaat actaaacaca
     8221 gaaagagatt ttaaatggaa acttactaca aagccattaa ctggaatgcc atcgaagatg
     8281 tcatcgacaa atcaacttgg gaaaaactga cggagcaatt ttggctcgat acacgtattc
     8341 ccttatcaaa cgacttggat gactggagaa agctatctaa caaagagaaa gacttggtcg
     8401 gaaaagtttt tggtggttta acccttcttg acactatgca atctgaaact ggggttcaag
     8461 cccttcgcgc agacatccgt acaccacatg aggaagctgt tttcaataac atccaattta
     8521 tggaatctgt ccacgctaaa tcttactcat caatcttttc taccttgaat actaaggctg
     8581 agattgaaga aattttcgaa tggaccaata ccaatcctta cctacaaaag aaggctgaga
     8641 ttgtcaacga aatctaccta aacggcagcc cacttgaaaa gaaagttgcc agcgtcttcc
     8701 tcgaaacctt cctcttctac tctggtttct tcactcccct ctactatctc ggtaacaaca
     8761 aactagccaa cgttgcagaa atcattaaat tgattattcg tgacgagtct gttcacggaa
     8821 cctacattgg ttacaaattc caacttggtt tcaatgaatt gcctgaagaa gagcaagaaa
     8881 aactcaaaga atggatgtac gacctactct atactcttta tgaaaatgaa gaaggctaca
     8941 cagagagtct ttatgacggt gttggttgga ctgaagaggt taaaaccttc cttcgctaca
     9001 atgccaataa agctctcatg aacatgggac aagatccact tttcccagat tcagctgaag
     9061 atgtcaaccc aatcgttatg aacggtattt caacaggaac ttccaaccat gacttcttct
     9121 ctcaagtcgg aaatggttac cttcttggcg aagttgaagc catgcaagac gatgactata
     9181 actacggttt agactaattc tccatcactc tcaatcatca aaaagtaaac tagaaacatc
     9241 aaagttataa cccaacaaaa atatcgaaag ttttgaaaac aaacttcgat atttttgttt
     9301 ttgtttcatt ttgttgtttt tgtatttgaa tgatgagttt gtttatggta agatagtagt
     9361 aggaaacgag gtgataatat gctcaaacaa gaaaaattaa ccaaaatttt agagatagta
     9421 aatagtaaag gaaccataac agttaaacag attatggacg aaatagccgt ttcagatatg
     9481 actgcaaggc gctatttaca ggaattagct gataaagatt tgctgattcg tgtgcatggt
     9541 ggagctgaaa aacttcgaac caactccctt ttgactaatg agcgatcaaa tattgaaaaa
     9601 caagccctcc aaacggcaga aaaacaagaa atagcccatt ttgcaggcag tctagtagaa
     9661 gaaagagaaa ctattttcat tggaccagga acaacattag agttttttgc gcgtgagttg
     9721 cctattgaca atatccgcgt cgtaaccaac agtctacctg tttttctgat tttaagcgaa
     9781 cgaaaattaa cagatttgat tttaataggt ggaaattatc gcgatattac aggtgctttt
     9841 gttggtacat tgaccctaca aaatctctct aatctccaat tttctaaagc tttcgttagc
     9901 tgtaatggta ttcaaaacgg agctctagct acttttagcg aggaagaggg agaggctcaa
     9961 cgcatcgctt taaataattc taataaaaaa tatttactcg cagatcatag taagttcaat
    10021 aagtttgatt tttatacttt ttataatata tcaaatcttg atactattgt ttcagattct
    10081 aaactaagtg attcaatcct ttttaagcta tctaaacaca ttaaagtcat caagccttaa
    10141 taaactgaaa gagcctgggt aacaactcaa tttcagaaga aaaaaagtaa atcttcccac
    10201 aataaaaagc atagtatcag gtgttgaaac acctgatact atgctttttt ctatatcaaa
    10261 gactttttgc ccaattcctc aaagctatac attgagaaat ctgcgactcg cttcctagtt
    10321 taaagttgct ctttgatttt cattgagtat aagcaacgtg attagataag agttttacag
    10381 agtactaaat ataagattta acttttttga gaaattggtt acgattattg aaacggcata
    10441 aaatctgaat caaaggagat agtatcccat tcttcaggat tgataaaatt taaaaataga
    10501 tttttaaatt cttccagatc agcatctgaa tgacaaatcc attctttacc agtcgagaca
    10561 taccattttc caagactttt caattcttca ctcgtcaaac acggtatttg agagcatttt
    10621 tcgaaattta taatataaac tttttcataa atagattgga taaaatcttt gaacatcttt
    10681 ttgacttact aaaattctat atctaatgac taattctact agtctataat ctgagtttcc
    10741 gctactttct tgtaccagtg agctgatttc ttaggataac gttcttgagt ttcaaaatct
    10801 acgtagaaga gaccataacg tttctcataa ccgtttgacc atgagaagac atccattaat
    10861 gaccaaatga agtaaccttt tacattagct ccatctgcaa tcgcatcaga caagatctcc
    10921 aagtgttgtt tcacgtaatc aatacgacca tcatcgtaaa cagtgttatc aacgaactca
    10981 tctttatatc caagaccatt ttcagtgatg tagattttct tatagttagg ataatctttc
    11041 ttcacgcgca tgatttggtc atacaaacct tgagggtaga taatccaatc ccaatccgtg
    11101 cgtggtacat agtcaggagc tacacgacga ccaacacctt tgatttgata cttagagctt
    11161 cctttttcac ctttaccatt atggataatt tcagtttctc catcaaaggc ttccatccag
    11221 tcactcatat agtagttgat tcctaggaaa tcattcaagt cttttgcagc ttctaatgct
    11281 gtaaaatctt cttcacgaag atccaaacta ccaccattga ctaataagat atggttgaca
    11341 ccttccatgg tttcagctga atagcgacct agataagttg cgtctaagat gaatttattg
    11401 tggatgatat cttccaactc agctgcacga acatctgctg gattttcagg atctagagga
    11461 tatttagtag gcagggcgtg aacaacacca atttcccctt tatagccttt ctctttgtac
    11521 aattttaccg cgcgtgcatg agacaccatc atattgtggt gtgattgaaa gactttggca
    11581 aggtcgtact ggatacctgg agggaatttc ccaaccaaat attgaccatc accgattggt
    11641 ccaatttcat taaaggttgt ccaatagttt acttctggaa attcttcaaa acagaaggca
    11701 gcgtagtcta caaaatgttc gatattttca cggtttaaga agtctccatt tgagtggaga
    11761 gcttctggag tgtcaaagtg atgaagagtt acaaaaggct caacatgacg tttgtgacac
    11821 tctgcaaata aattatgata aaactcaaca cctttagcat ttacttggcc gtaaccagtc
    11881 gggaaaatac gtgaccaagc aatagaaatt cgaataccat tgacaccata ctcttctgct
    11941 agcttgaggt caactggata tcgattgtaa aaatcactag ctggttcggc agtgtaccag
    12001 tagttatcct caagatattt atcccaagca actggtcctt ttccatcagt atgtgtagca
    12061 ccttctgctt gataagcagc tgttgcgcca ccgaaaataa agtcttttgg aagtgttttt
    12121 gtcatttttt tcacctattt cttgatttaa ataaagtaaa agtgagagga gaggagtcag
    12181 tgagccatgc ttctccatct cacttcttgt accaagtcac tgaattgtga catgaggagg
    12241 taaaaacgat atctttttac cgacgaatta ataaggcgat taggaaattc gccatagcga
    12301 tttccgtaac gatgggagac tgtttcacag ttcctagcct taatcgaatt gctcttgtac
    12361 gaatgctagg gcaccttttc catcacgagt taatttgatg tattgagcgc cttctgtctt
    12421 agcaagttta ataccgagct tatctgtttc tgccttcata tcttcaaagt ttgaagcaac
    12481 ttgaggagca aggataacca aatcaaactc tggcaacatt tcacggtgag caccatagcc
    12541 gcctgctgtt gctttcacag ggacattgta ttctgctgct gccttattca aagcatttgc
    12601 aaggagtcca cttgtacctc caccagcaca gagaacgagg acatttgttt cttcagtgat
    12661 ggtattttgt gctgcatcga cacccgcttt ttcaagaata gcatccgctt ttacagtgtt
    12721 gaagtttgca gcaacttttt ctttcaattc agatgaagag tttcctttcc gttcttcttc
    12781 taaaatttga tggtcataaa ctttaacaaa tggataatag attaaagtgt cgataatgat
    12841 taaagttata gccaagacga atgacaatgg agccagcgcc gttcccataa caataccaat
    12901 tggagcaggt gttgtccaag gtaaaataat actgaaacta ttcatttgta gaacatctac
    12961 aaaaaatttc ataatccaaa cattgataat aggagcagta acaaacggaa taaagaagat
    13021 aggatttaaa acaattggag caccaaatag gattggttca tttacgccaa agaaagtagg
    13081 aactacagac gcacgtccga caattctatt tctttttgat ttacataacc acataaacat
    13141 aaatggaact actagtgttg caccagtacc acccattgtt acaacaaaag tttgagtaac
    13201 tggatttaaa attttatctg cgtgcatacc agcttgcaca agctgaacat tagcttctat
    13261 atttgcataa ctgatagcta caattaaagg ttctacaaca gatggcccat gaattccaac
    13321 aaaccaaaag aaagcataag caccaaatac aatagctaaa ccgatataac catcagtagc
    13381 tgaaaataga ggggctaata ttttaccaac agattctgct acatttgtac caaaaatatt
    13441 tctaacaatt aaatccaatc catatattga aagaacagat aaggcaaacg gaataacatc
    13501 tttaaaaact tgtgcaatat ttggtggaac ctcttcagga agtctaatgg ttacattatt
    13561 tttaatacat actttataga tatttactgt aataaaagct gccaaaaatg cagtaagtaa
    13621 tcctctagta cctaaaagac cattagcaaa tccaccttca attggatcag ctgccagtat
    13681 taacaatcca acaacagctg ctaaaaaagt tgacatgtag ttgatttggt tggttttctc
    13741 catactacgt gtattaactg aatctgttaa cgattttgca gttgtcccag ctactaagag
    13801 agctaaaatt cccattgagt agttgtaagg tttcaaaata aaagctaact gttcatcaga
    13861 ccatttaaac ccaaaaatat tgggcacagc agctattagt ataaaaatac ttgagaataa
    13921 tactgctggc atactggaaa taaaaccatc ttttatcgct cttaagtata tatttctcga
    13981 taatttttca aagaaaggct ttcctttctc aataaaaatt attaacttat ccattttatt
    14041 taactcctct cttgtaaagt tcaattaaat ggtgcattag gtcttttaac aagatagttg
    14101 tcatcaagtg atcttgacca tgcatcatgg tcacactata cgctaagtcc tcaccagaag
    14161 cttccttagt caatagactt gtttgcgcgt ggtgagcctc tgcaatacag ctaccagctt
    14221 cctctaccag agcgtccgct ttttcaaaat caccagcttc agcagccttc aaggcttcca
    14281 atagttttga acgagcatcg ccagcatagg ctacgatttc aaaacctaac aatgttactt
    14341 cttctctatt catgatagaa ttctccttat atagttttaa ataaattttt atgacaataa
    14401 acgttggata tgtagaacta gataaactcg ttcactttta tacaaatcaa gacccgtatg
    14461 ttgcgtaatc acatcataga tcttggaacc aatctcgaag gcttttggat aggattgttt
    14521 aatatgatct tccatatcca gaagtgattg gttatcatct ctagatctgt ctaaataatc
    14581 caagaaataa ttcaaatgga tcataaagcg atcatagaaa tggttattct ttttagttcg
    14641 ttgaattgca tagtccgtta aaacttcttc aacattcctg agaatttctt tcctcttatc
    14701 aatcgactcc acaagttcca cttcattttc accttcagca ttaatgaaat gataagcaat
    14761 ccgaataatt tcgtcctcag gaaaatgatc tgctagcttc tgacggtaaa tttcaaaagc
    14821 ttcatttgcg atttgaaaag cgacaggata cttagcggaa atatctggca gattactatc
    14881 cttgtacctt ccttgagtta gagcttgata agaacagtaa atatgatctg tcaaggttac
    14941 atagagatac tcttgaatcg gataatgata tttctttgat agcttatcaa tgatttcata
    15001 ggtcactgtg ataaaatcaa gcggaacatc tttgagaaga gccataaagt tttctctgga
    15061 ctcttcggtc ttcatccgaa agattttctc aacctgattt tcagcaatca aatccccctt
    15121 cttctttccg aatgcaatcc ccttaccaat tacaatcacc tcttctccct tatcatttct
    15181 gacaagcgag acattgtgat tcattggatt tagaattcga tacatgtcaa cctcctttta
    15241 tattttaaag gtatatgagt acaaaaaatg accacaaatg aactagaaaa tcagctgatt
    15301 tctaattcac ctgtgatcat gcctaatatt acttagtaac actcaccttg tattaacttg
    15361 tgatttaagt atagcacaag taagttattt tgtaaacctt tacatacaac tttttttaaa
    15421 tttttttaga ttcatgttcc taaactagga ggactttctt acacacgttc tttccatgaa
    15481 gtcgctgttg tttgaagaac tttattgagc tcatcaatgt tttcaaatcc agttgtgcga
    15541 agccattcgc gagctgctgc ttcaccatct ttgatgtaag cttcaactga ccctgcccat
    15601 gtagcacggc cacaaagaac tccgttaaag tttgcacctg attcatgagc aaatacaaga
    15661 gtatcttgga agagtttagc tgatacacca gcactcaagt agatgtatgg caagttcgtt
    15721 gcttcatctt gcgctttgaa gaaggctgct gcttcttcac gtgtataaac tacttcacct
    15781 tcagcgaagc cttcaacata tttaatgtta acaggaactt caactttcaa gacatcaatg
    15841 ttaaagcgtg ggtctgaaaa gactttcata gcgccgataa ctttgtgtgg ttttactttc
    15901 gcgtattcta cagaacctgc atccgcaatt ttttcatcgt aagcaaggat ttcaaggaag
    15961 aatgggatat cttcagccac acactcagaa ccgatgcgtt cgatgtaggc ttgtttttct
    16021 tgattgagtt cgtctgagct atctacatca tagtaaagca agaatttaac tgcatctgca
    16081 ccttcttctt taatacgttt tgcagaccaa acatccaagc agtctggcaa gcgttttgtg
    16141 cttgttgtgt cataacctgt tttttcataa gcaaggagaa gaccagcttt ttcatcaaga
    16201 gctttagttg ctggaagtcc atactcaggg tcaagaagca tagatgaagc gtatttagtc
    16261 aattcatctg ctaccaagac tttaagttct tccatttggg ccacagttgg ttcttctgtt
    16321 tggtgttgag ccatgaggcg tttcaaagca ccacgttggt caaatgcaag agctgagatg
    16381 ataccatttt catcagaaag tttttctaag cgtacacgtt tttgttctgt taaagccatt
    16441 ttatacctct tttactatta attgatcata tagagcttga tagttggcca tgttgacatg
    16501 accagtcatt ttttcttgag cattgagcat accaaggaca tttgccttga tgagtaatcc
    16561 tgcatccgat tctttgtgaa gaagtcctga agaaattcct gccacagtag agtctccaga
    16621 tccaacagga tttaccacct gaattctagg aatatctacc ttgtagaaag tgtcaccatg
    16681 tttggcaaaa gtaccgttgg caccaagtga aacgataatc cattcaatcc ctgtaaacaa
    16741 agattcttga aggacttctt ttaattcctc caaatcctca gaaacttctc ttcctagaag
    16801 ctgagacaat tcctcattat tgggtttgat tactgtcggt ttatggggtg attcaagaac
    16861 cgcctgaagt gctgcaccag agcagtccaa gactactagc ttgccagctt gattagcaag
    16921 ctctaccaag ctcgcatagt aatcaactgg aaggccagct ggcagactac ctgagatggc
    16981 tactacttca actgactcca agagtttttt gaaatgttcc aaaaagtctt gaccttcctg
    17041 ttccaatact tcaggacctt tttcaagaac ttctgtttgg ttgtcaccgt ggagaatagc
    17101 gatacagtta cgagtttctc cctgaataga aaagaaatct ttctttactt gatcatcgat
    17161 atgttcaacc aaaaactcac caagtttgcc acccactaaa ccagtagcaa gaacagaatc
    17221 accaaattct gaaagtactc gggtaacatt aagtccctta ccaccagccg ttttggttac
    17281 atccaccaca cgattgacag tatcaatctt caactcatcc aagggatagg aaatatcaat
    17341 ggatgggttc attgtgactg ttaaaatcat aggtcacctc ttagtcgtgg tattctccgc
    17401 gatcccattt ttcaaggaat tctgtaaaga agtttgcgtc tgtttgttga gcattgtgac
    17461 tttcaaggtg ttcaattttc gcaatcaatt tcttgttttc ttcagatggt ttgtattcag
    17521 catgaatgaa agcttcgatg atatcacaca taagcaattc accagtaatc ttaccaccaa
    17581 agccgataac gttagcgttc aattgttctt tagcataaag ggctgttgtc atatcacgaa
    17641 ccaaggcaga acgaacacct ggaactttat ttacagcgtt gttgatacca acaccagtac
    17701 cacagataca taccccaaga tcagcttggc cgctagttac agcttcccct acttttttac
    17761 caaagattgg gtagtgagtc cgtgtatggt catatgtacc aaagtcaatg acttcatatc
    17821 cttttgattt caaaaattct gaaaccgcca ttttttcatc tgttacgatg tggtcgcatc
    17881 caattgcaat tctcattttt aacttacctt tcttactgta atctaattag cccattttgt
    17941 tcaacatgtc aacccggatt tgatgacgtc caccgtcgta tttaccatta acaaatcctt
    18001 tagcgatgtt tttagccaat tcatcaccaa caagttgtgc ccccatagtg atcatacgtg
    18061 agttgttgtg gccacgagtc atataagctg aacgttcgtc agatacttct gcagcaacca
    18121 ttcctttgat cttagttgca accataaatg gaccagctcc ataagcatca atcacgatac
    18181 caaggttttg ttcttctttg tttacttctg cagcaacagc gagagtcaca tcaacaaagt
    18241 cttgaccttc agctgtaaca tccacaaggt ggaagttttc tttttctaag aagtctttca
    18301 caacttcttt caatctcaaa cctgcagcat ctgcaccgat aacaatagac atattgtata
    18361 ctccttttta ttttttctat gctggattcc agcagtgtat tggctgtctt taaaaaacag
    18421 tcaattagtc ctcacaaaca taatatacta ctattgtttg aagaagtcaa tagtttgtgt
    18481 ttgtttttgt tatttatttt ttactttttt ataaaacttc tatctcaaac cctaattctt
    18541 caacctgatt ggcttctaag agacaaacat tcttcttatc ttctaaatga tctccttctt
    18601 caaggaatgt tgacaagcca gaccatggtt caaaggtaat gaaaggtccc ttgttcaaag
    18661 ttgaccagat gatgaggttt ggaaattctg caaaatgcac tttcaatccc ttatcatgtt
    18721 taagagaacg aagggcaatt gttcgagatt gcaattcatc caaagtcact gcatctgtgc
    18781 tgaaaagatc ataactaaga tctatttctt tttgtccctc tagccatgga cttctatctt
    18841 ggaaatccaa catacctgtt tctgggaaag gacgtggaac agagcaagtc tcttctttct
    18901 cagactctag ataataatct tcatagactc catcatcaag tagaggacaa ttaaatcctg
    18961 gatgtccacc aataaagtaa ggcatgacct tgctagtttc tttattagac ttcctgcaaa
    19021 actagaatcc tagttcatga ttgataatac cagcactcaa attcattcgt a
//
LOCUS       DBEJAU010000044        18687 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC323 isolate 683620
            SAMN38261939-rid24807223.denovo.044, whole genome shotgun sequence.
ACCESSION   DBEJAU010000044 DBEJAU010000000
VERSION     DBEJAU010000044.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261939
            Sequence Read Archive: SRR26833919
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 18687)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18687)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576303.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576303.1
            Genome Coverage       :: 154x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/19/2025 01:05:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,121
            CDSs (total)                      :: 2,078
            Genes (coding)                    :: 1,943
            CDSs (with protein)               :: 1,943
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 36
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 72 of 135
            Pseudo Genes (incomplete)         :: 63 of 135
            Pseudo Genes (internal stop)      :: 51 of 135
            Pseudo Genes (multiple problems)  :: 46 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18687
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261939-rid24807223.denovo.044"
                     /strain="GPSC323"
                     /isolate="683620"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            complement(112..387)
                     /locus_tag="ACL29Z_001606"
     CDS             complement(112..387)
                     /locus_tag="ACL29Z_001606"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002950996.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0030261 - chromosome condensation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HU family DNA-binding protein"
                     /protein_id="HGR0069886.1"
                     /translation="MANKQDLIAKVAEATELTKKDSAAAVEAVFAAVADYLAAGEKVQ
                     LIGFGNFEVRERAERKGRNPQTGKEMTIAASKVPAFKAGKALKDAVK"
     gene            complement(493..1332)
                     /locus_tag="ACL29Z_001607"
     CDS             complement(493..1332)
                     /locus_tag="ACL29Z_001607"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000161411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005504 - fatty acid binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HGR0069887.1"
                     /translation="MTKIKIVTDSSVTIEPELVKQLDITIVPLSVMIDNVVYSDADLK
                     EEGKFLQLMQESKNLPKTSQPPVGVFAEIFEDLCKDGGQILAIHMSHALSGTVEAARQ
                     GASLSTADVTVVDSSFTDQALKFQVVEAAKLAQEGKDMEAILSHVEEVKNHTELYIGV
                     STLENLVKGGRIGRVTGLLSSLLNIRAVMQMKDHELQPMVKGRGTKTFKKWLDELITS
                     LSERAVAEIGISYSGSDDWAKEMKESLQAYVEKPISVLETGSIIQTHTGENAWAILIR
                     YHS"
     gene            1474..2322
                     /locus_tag="ACL29Z_001608"
     CDS             1474..2322
                     /locus_tag="ACL29Z_001608"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000592058.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HGR0069888.1"
                     /translation="MIKKIYPIFTILLGAAIYAFGLTYFVVPHHLFEGGATGITLITF
                     YLFKIPVSLMNLLINIPLFILAWKIFGAKSLYSSLLGTLALSGWLAFFEHIPLHIDLQ
                     DDLLITALIAGILLGIGLGIIFNAGGTTGGTDILARILNKYTHISIGKLLFILDFCIL
                     MLILLIFKDLRLVSYTLLFDFIVSRVIDLIGEGGYAGKGFMIITKRPDQLAKAINDDL
                     GRGVTFISGQGYYSKENLKIIYCIVGRNEIVKTKEMIHRIDPQAFITITEAHEILGEG
                     FTFEKE"
     gene            complement(2415..3332)
                     /locus_tag="ACL29Z_001609"
     CDS             complement(2415..3332)
                     /locus_tag="ACL29Z_001609"
                     /EC_number="2.7.1.26"
                     /EC_number="2.7.7.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000587449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003919 - FMN adenylyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional riboflavin kinase/FAD synthetase"
                     /protein_id="HGR0069889.1"
                     /translation="MIITIPIKNQKDIGTPSDSVVVLGYFDGIHKGHQELFRVANKAA
                     RKDLLPIVVMTFNESPKIALEPYHPDLFLHILNPAERERKLKREGVEELYLLDFSSQF
                     ASLTAQEFFATYIKAMNAKIIVAGFDYTFGSDKKTAEDLKDYFDGEVIIVPPVEDEKG
                     KISSTRIRQAILDGNVKEAGKLLGAPLPSRGMVVHGNARGRTIGYPTANLVLLDRTYM
                     PADGVYVVDVEIQRQKYRAMASVGKNVTFDGEEARFEVNIFDFNQDIYGETVMVYWLD
                     RIRDMTKFDSVDQLVEQLKADEEVTRNWS"
     gene            3827..3960
                     /locus_tag="ACL29Z_001610"
                     /pseudo
     CDS             3827..3960
                     /locus_tag="ACL29Z_001610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000617844.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus and C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR03943 family protein"
     gene            complement(4286..4579)
                     /gene="rpmA"
                     /locus_tag="ACL29Z_001611"
     CDS             complement(4286..4579)
                     /gene="rpmA"
                     /locus_tag="ACL29Z_001611"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018376869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0000315 - organellar large ribosomal
                     subunit [Evidence IEA];
                     GO_component: GO:0022625 - cytosolic large ribosomal
                     subunit [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L27"
                     /protein_id="HGR0069890.1"
                     /translation="MLKMTLNNLQLFAHKKGGGSTSNGRDSQAKRLGAKAADGQTVTG
                     GSILYRQRGTHIYPGVNVGRGGDDTLFAKVEGVVRFERKGRDKKQVSVYPIAK"
     gene            complement(4596..4940)
                     /locus_tag="ACL29Z_001612"
     CDS             complement(4596..4940)
                     /locus_tag="ACL29Z_001612"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000613691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal-processing cysteine protease Prp"
                     /protein_id="HGR0069891.1"
                     /translation="MIQAVFERAEDGELRSAEITGHAESGEYGLDVVCASVSTLAINF
                     INSIEKFAGYEPILELNEDEGGYLMVEIPKDLPSHQREMTQLFFESFFLGMANLSENS
                     SEFVQTRVITEN"
     gene            complement(4956..5270)
                     /gene="rplU"
                     /locus_tag="ACL29Z_001613"
     CDS             complement(4956..5270)
                     /gene="rplU"
                     /locus_tag="ACL29Z_001613"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018374562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L21"
                     /protein_id="HGR0069892.1"
                     /translation="MSTYAIIKTGGKQVKVEVGQAVYVEKLNVEAGQEVTFNEVVLVG
                     GENTVVGTPLVAGATVVGTVEKQGKQKKVVTYKYKPKKGSHRKQGHRQPYTKVVINAI
                     NA"
     misc_feature    complement(5306..5393)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00559"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="ribosomal protein L21 leader region; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF00559"
     gene            complement(5452..6156)
                     /locus_tag="ACL29Z_001614"
     CDS             complement(5452..6156)
                     /locus_tag="ACL29Z_001614"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004241810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YoaK family protein"
                     /protein_id="HGR0069893.1"
                     /translation="MGGKMRLLPIRKISRQSKRLALFLTFCAGYVDAYTFIVRGNTLV
                     AGQTGNVVFLSVELIKNNVSDVRDKVLTLLAFMMGVFLLTIYKEKLRIVKKPILSLIP
                     LAILSIIIAFVPQTVDNIYLVPPLAFCMGLVTTAFGEVSGIAYNNAFMTGNIKRTMLA
                     FGDYFRTKHTPFLREGFIFVSLLSSFVLGVVFSAYLTIFYHEKTILGVPIMMSVFYLS
                     MLFASWQKKVKEKASF"
     gene            6558..6857
                     /locus_tag="ACL29Z_001615"
     CDS             6558..6857
                     /locus_tag="ACL29Z_001615"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008808250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0008150 - biological_process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YbaB/EbfC family nucleoid-associated protein"
                     /protein_id="HGR0069894.1"
                     /translation="MMNMQNMMRQAQKLQKQMEQSQAELAAMQFVGKSAQDLVQATLT
                     GDKKVVSIDFNPAVVDPEDLETLSDMTVQAINSALEQIDETTKKKLGAFAGKLPF"
     gene            complement(7199..8173)
                     /gene="pta"
                     /locus_tag="ACL29Z_001616"
     CDS             complement(7199..8173)
                     /gene="pta"
                     /locus_tag="ACL29Z_001616"
                     /EC_number="2.3.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004252952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008959 - phosphate acetyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0006086 - acetyl-CoA biosynthetic process
                     from pyruvate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate acetyltransferase"
                     /protein_id="HGR0069895.1"
                     /translation="MEVFESLKANLVGKNARIVLPEGEEPRILQATKRLVKETEVIPV
                     LLGNPEKIKIYLEIEGIMDGYEVIDPQHYPQFEEMVSALVERRKGKMTEEDVRKVLVE
                     DVNYFGVMLVYLGLVDGMVSGAIHSTASTVRPALQIIKTRPNVTRTSGAFLMVRGTER
                     YLFGDCAININPDAEALAEIAINSAITAKMFGIEPKIAMLSYSTKGSGFGESVDKVVE
                     ATKIAHDLRPDLEIDGELQFDAAFVPETAALKAPGSTVAGQANVFIFPGIEAGNIGYK
                     MAERLGGFAAVGPVLQGLNKPVNDLSRGCNADDVYKLTLITAAQAVHQ"
     gene            complement(8217..9113)
                     /locus_tag="ACL29Z_001617"
     CDS             complement(8217..9113)
                     /locus_tag="ACL29Z_001617"
                     /EC_number="5.4.99.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001209987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0009982 - pseudouridine synthase activity
                     [Evidence IEA];
                     GO_process: GO:0001522 - pseudouridine synthesis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HGR0069896.1"
                     /translation="MRFEFIADEHVKVKTFLKKHEVSKGLLAKIKFRGGAILVNNQPQ
                     NATYLLDVGDYVTIYIPAEEGFETLEAIEHPLDILYEDDHFLVLNKPYGVASIPSVNH
                     SNTIANFIKGYYVKQNYENQQVHIVTRLDRDTSGLMLFAKHGYAHARLDKQLQKKSIE
                     KRYFALVKGNGHLEPEGEIIAPIARDEDSIITRRVAKGGKYAHTSYKIVASYGNIHLV
                     YIHLHTGRTHQIRVHFSHIGFPLLGDDLYGGSLEDGIQRQALHCHYLSFYHPFLEQDL
                     QLESPLPDDFSNLITQLSTNTL"
     gene            complement(9110..9928)
                     /locus_tag="ACL29Z_001618"
     CDS             complement(9110..9928)
                     /locus_tag="ACL29Z_001618"
                     /EC_number="2.7.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000799053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003951 - NAD+ kinase activity [Evidence
                     IEA];
                     GO_process: GO:0006741 - NADP biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD kinase"
                     /protein_id="HGR0069897.1"
                     /translation="MKNTGKRIDLIANRKPQSQRVLYELRDRLKRNQFILNDTNPDIV
                     ISIGGDGMLLSAFHKYENQLDKVRFIGLHTGHLGFYTDYRDFELDKLVTNLQLDTGAR
                     VSYPVLNVKVFLENGEVKIFRALNEASIRRSDRTMVADIVINGVPFERFRGDGLTVST
                     PTGSTAYNKSLGGAVLHPTIEALQLTEIASLNNRVYRTLGSSIIVPKKDKIELIPTRN
                     DYHTISVDNSVYSFRNIERIEYQIDHHKIHFVATPSHTSFWNRVKDAFIGEVDE"
     gene            complement(9912..10583)
                     /locus_tag="ACL29Z_001619"
     CDS             complement(9912..10583)
                     /locus_tag="ACL29Z_001619"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000171686.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0015969 - guanosine tetraphosphate
                     metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GTP pyrophosphokinase family protein"
                     /protein_id="HGR0069898.1"
                     /translation="MTLEWEEFLDPYIQAVGELKIKLRGIRKQYRKQNKHSPIEFVTG
                     RVKPIESIKEKMARRGITYATLEHDLQDIAGLRVMVQFVDDVKEVVDILHKRQDMRII
                     QERDYITHRKASGYRSYHVVVEYTVDTINGAKTILAEIQIRTLAMNFWATIEHSLNYK
                     YQGDFPDEIKKRLEITARIAHQLDEEMGEIRDDIQEAQALFDPLSRKLNDGVGNSDDT
                     DEEYR"
     gene            10711..11280
                     /locus_tag="ACL29Z_001620"
     CDS             10711..11280
                     /locus_tag="ACL29Z_001620"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000681289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CYTH domain-containing protein"
                     /protein_id="HGR0069899.1"
                     /translation="MKHLEIELKILLKKDEYNRLKDQFTGVTPVLQTNYYIDTPDFEL
                     REKKVAMRIRTFEDWAELTLKVPQSVGNMEYNQKLQLKDAENYLSKEELPQGLVLDEL
                     AKHGIQSKNWQVLGCLTTLRYEMKTAIGLMALDQSRYFDITDYELELEVENHEQGKQD
                     FRQFLEKNQISYQKAPSKLVRFVKSMKNS"
     gene            11393..12352
                     /locus_tag="ACL29Z_001621"
     CDS             11393..12352
                     /locus_tag="ACL29Z_001621"
                     /EC_number="2.7.6.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001280885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-phosphate diphosphokinase"
                     /protein_id="HGR0069900.1"
                     /translation="MSDRKNMKLFALNSNQEIAQKIAQAVGVPLGKLSSRQFSDGEIQ
                     VNIEESVRGYDVYIIQSTSFPVNNHLMELLIMVDACVRASAHSINVVLPYFGYARQDR
                     IACPREPLTAKLVANMLVKAGVDRILTLDLHAVQVQGFFDIPVDNLFTVPLFAKHYCD
                     KGLLGSDVVVVSPKNSGVKRARSLAEYLDAPIAIIDYPQDDATRNEGYIIGDVEGKKA
                     ILIDDILNTGRTFSEASKIVEREGATEIYAVSSHGLFVEGAAELLDNTNIKEILVTDS
                     VATKEKTPKNVCYITASELIGDAIVRIHERKPVSPLFAYNKKK"
     gene            12362..13477
                     /locus_tag="ACL29Z_001622"
     CDS             12362..13477
                     /locus_tag="ACL29Z_001622"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000639661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase family protein"
                     /protein_id="HGR0069901.1"
                     /translation="MIYLDNAATTPMSAVAISAMTKVMQETHGNPSSIHGHGRQAGKL
                     LREARQELAQLLRTKPQHIFFTSGGTEGNNTTIIGYCLRHQEQGKHIITTAIEHHAVL
                     ETIDYLVQHFGFEATIIQPENQEITAQQIQKALRDDTILVSTMFANNETGNLLPIAEI
                     GQILKQHPAAYHVDAVQAIGKIPIHSEELGIDFLTASAHKFHGPKGIGFLYASSMDFD
                     SYLHGGDQEQKKRAGTENLPAIVGMVAALKEDLEKQEEHFQHVQNLETAFLAELEGIQ
                     YYLNRGKHHLPYVLNIGFPGQKNDLLLLRLDLAGISISTGSACTAGVVQSSHVLKAMY
                     GANSERLKESLRISLSPQNTVEDLQTLAKTLKEIIGG"
     gene            13482..13829
                     /locus_tag="ACL29Z_001623"
     CDS             13482..13829
                     /locus_tag="ACL29Z_001623"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000863538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1831 domain-containing protein"
                     /protein_id="HGR0069902.1"
                     /translation="MAFEKIIQLKNCRYDYTLSPSVKKFTLKDNTFFETKVGNYELTR
                     LLEKVPNSGEGFQLKIIINKELTGAKINITDKFGLRLVDIFKSEDHHIHQEKFYFLMD
                     SLVERGVFTKSER"
     gene            13837..14052
                     /locus_tag="ACL29Z_001624"
     CDS             13837..14052
                     /locus_tag="ACL29Z_001624"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000462494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4649 family protein"
                     /protein_id="HGR0069903.1"
                     /translation="MFELTYKDCYHVERTLKYEDHEALMLTLSGCVTLPDTLYVTSLT
                     FRGKKVYQGLVGDLYRFLSHADFLHQN"
     gene            14135..14776
                     /locus_tag="ACL29Z_001625"
     CDS             14135..14776
                     /locus_tag="ACL29Z_001625"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000653420.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="redox-sensing transcriptional repressor Rex"
                     /protein_id="HGR0069904.1"
                     /translation="MKDKQFAIPKATAKRLSLYYRIFKRFHAEKIERANSKQIAEAIG
                     IDSATVRRDFSYFGELGRRGFGYDVKKLMTFFADLLNDNSITNVMLVGIGNMGHALLH
                     YRFHERNKMKIIMAFDLDDHPEVGTQTPDGIPIYGISQIKDKIKDADVKTAILTVPSV
                     KSQEVANLLVDAGVKGILSFSPVHLHLPKDVVVQYVDLTSELQTLLYFMRKED"
     gene            14794..15483
                     /locus_tag="ACL29Z_001626"
     CDS             14794..15483
                     /locus_tag="ACL29Z_001626"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gamma-glutamyl-gamma-aminobutyrate hydrolase
                     family protein"
                     /protein_id="HGR0069905.1"
                     /translation="MKKPVIGITGNEKTHPDDDIMMSYAAKGFVEGVKDAGGIPIILP
                     IGDQEMACHYISLIDKLILTGGQNVDPKFYGEPKTIDSDDYHLQRDIFELALIKEAIK
                     QKKPIFSVCRGTQLFNVAMGGTLYQDIEDHWQDSSVEYTTQRLVTEPDTVLQEIYGEI
                     SHINSFHHQSIKDLAPNLKVVAHDPKDGIIEAVMSTDDVAFLGVQWHPELLFENRPKD
                     KKLFDYVVNEL"
     gene            complement(15480..16160)
                     /gene="radC"
                     /locus_tag="ACL29Z_001627"
     CDS             complement(15480..16160)
                     /gene="radC"
                     /locus_tag="ACL29Z_001627"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000286923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RadC"
                     /protein_id="HGR0069906.1"
                     /translation="MYSISFQEDSLLPRERLAKEGVEALSNQELLAILLRTGTRQASV
                     FEIAQKVLNNLSSLTDLKKMTLQELQSLSGIGRVKAIELQAMIELGHRIHKHETLEME
                     SILSSQKLAKKMQQELGDKKQEHLVALYLNTQNQIIHQQTIFIGSVTRSIAEPREILH
                     YAIKHMATSLILVHNHPSGAVAPSQNDDHVTKLVKEACELMGIVLLDHLIVSHSNYFS
                     YREKTDLI"
     gene            complement(16203..18494)
                     /gene="pcrA"
                     /locus_tag="ACL29Z_001628"
     CDS             complement(16203..18494)
                     /gene="pcrA"
                     /locus_tag="ACL29Z_001628"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000992850.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0003678 - DNA helicase activity [Evidence
                     IEA];
                     GO_process: GO:0006268 - DNA unwinding involved in DNA
                     replication [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA helicase PcrA"
                     /protein_id="HGR0069907.1"
                     /translation="MNALLNGMNDRQAEAVQTTEGPLLIMAGAGSGKTRVLTHRIAYL
                     IDEKLVNPWNILAITFTNKAAREMKERAYSLNPATQDCLIATFHSMCVRILRRDADHI
                     GYNRNFTIVDPGEQRTLMKRILKQLNLDPKKWNERTILGTISNAKNDLIDDVAYAAQA
                     GDMYTQIVAQCYTAYQKELRQSESVDFDDLIMLTLRLFDQNPDVLTYYQQKFQYIHVD
                     EYQDTNHAQYQLVKLLASRFKNICVVGDADQSIYGWRGADMQNILDFEKDYPKAKVVL
                     LEENYRSTKTILQAANEVIKNNKNRRPKNLWTQNADGEQIVYYRADDELDEAVFVART
                     IDELSRSQNFLHKDFAVLYRTNAQSRTIEEALLKSNIPYTMVGGTKFYSRKEIRDIIA
                     YLNLIANLSDNISFERIINEPKRGIGPGTVEKIRDFANLQNMSMLDASANIMLSGIKG
                     KTAQSIWDFANMMLDLREQLDHLSITELVESVLEKTGYVDILNAQATLESKARVENIE
                     EFLSVTKNFDDTTDVTEEETGLDKLSRFLNDLALIADTDSGSQETSEVTLMTLHAAKG
                     LEFPVVFLIGMEENVFPLSRATEDSDELEEERRLAYVGITRAEKILYLTNANSRLLFG
                     RTNYNRPTRFINEISSDLLEYQGLARPANTSFKASYSSGSISFGQGMSLAQALQDRKR
                     GAAPKSIQSSGLPFGQFTAGAKPASSEANWSIGDIALHKKWGEGTVLEVSGSGARQEL
                     KINFPEVGLKKLLASVAPIEKKI"
BASE COUNT         5731 a         3940 c         3411 g         5605 t
ORIGIN      
        1 aatattttcg gaacattcaa ctttttaact ctatttatta ctagatttca taattaaaaa
       61 gcctactgac caagctagaa agcttgatac aataggcttt ttaaagactg attatttaac
      121 agcgtcttta agagctttac cagctttgaa tgctggtact ttagaagctg caattgtcat
      181 ttctttacca gtttgtgggt tgcgaccttt acgttctgcg cgctcacgaa cttcaaagtt
      241 accaaaaccg atcaattgaa ctttttcacc agctgcaaga tagtcagcta ctgctgcaaa
      301 tacagcttca actgctgctg ctgagtcttt cttagtcaat tctgtagctt ctgctacttt
      361 agcgatcaaa tcttgtttgt ttgccatgtt aatgattcct ccaaataatt tctaattaac
      421 aaatataatc atatcctaaa atccctttta ggtcaagtta aaaacgctat ttcttcccat
      481 tttatttatt ttttaggagt ggtaacgtat caaaatagcc caagcgttct cacccgtgtg
      541 agtttgaata atggaacccg tttccaaaac agaaattggc ttttcaacat aagcttgtaa
      601 gctttctttc atctcttttg cccaatcatc actaccagaa tatgaaattc caatctctgc
      661 tacagcacgt tcagaaagcg atgttatcaa ctcatctaac cattttttaa atgttttagt
      721 tccacgacct ttaaccattg gctgcaattc atggtctttc atttgcatga cagcacggat
      781 attgagaaga gagctcaaca agccagttac acggccaatt cgtccacctt tgacaagatt
      841 ttccaaagtt gaaacaccaa tataaagctc tgtatggttt ttaacctctt ctacatgaga
      901 taaaattgcc tccatatctt taccttcttg agctaacttc gcagcctcaa caacttggaa
      961 tttcagggct tggtcagtga aggaactatc aacaacagtc acatctgcag tagataggct
     1021 agcaccttgg cgtgctgctt ctaccgtacc cgaaagagca tgggacatat gaatagcaag
     1081 aatctggcca ccatctttgc ataggtcttc aaaaatctca gcaaagacac ctacaggtgg
     1141 ctgacttgtt ttcggaagat tcttactttc ttgcatcaac tgaagaaatt taccttcttc
     1201 tttcaaatcc gcatcagaat aaacaacatt atcaatcatt acagataatg gaacaattgt
     1261 aatatctaat tgctttacta gttcaggttc aatagtaaca gatgaatcgg ttacaatctt
     1321 aatttttgtc atagtatcaa tctttctatt ttaggattca gattggtttc cttacttcta
     1381 attatatcaa aaaaaagatt aaaaatccta atggagtcaa tcaaattttc cgtaaaattt
     1441 gatataatca acttataaga aaagaggtgt cctatgatta aaaaaattta ccccattttt
     1501 accattttac taggtgctgc tatttatgct tttggactga cttattttgt agttccccat
     1561 catctctttg aaggaggggc gacaggcatt accctcatca ccttttatct ttttaaaatc
     1621 cctgtttccc tcatgaacct gctgattaat attccccttt tcatcctagc ttggaagatt
     1681 tttggagcca aatccctcta ttctagttta ctaggaacct tagctttgtc cggctggtta
     1741 gctttttttg agcatattcc ccttcatatt gatcttcaag atgatttact aatcacagcc
     1801 cttatagcgg gaatcctatt gggaattggc cttggaatta tttttaatgc tggaggtaca
     1861 actggcggaa ctgatattct agctcgtatt ctcaacaaat acactcatat atccatagga
     1921 aaactgctct ttatcttaga tttttgtatt ctcatgttga ttctcctaat cttcaaggat
     1981 ttgagattgg tttcctacac gcttttgttt gattttattg tttctcgtgt tattgatttg
     2041 attggtgaag gaggatatgc cggcaaaggc tttatgatta tcacaaaacg tcctgaccaa
     2101 cttgctaagg cgattaatga tgacctcgga agaggtgtta cttttatttc tggtcaaggc
     2161 tactatagta aagaaaattt gaaaatcatt tactgtattg tcggaagaaa tgaaattgtg
     2221 aaaacgaagg aaatgattca tcgaatcgat cctcaagcct ttataactat tacagaagcc
     2281 catgaaatcc taggagaagg cttcaccttt gaaaaagaat aaaaagaggt agtgtcgtga
     2341 cctcaaaagt tagactaaat catctatctt ttgggttaca gacaacctct tttttgtttt
     2401 atttactcaa gctcttaaga ccaattccga gttacttctt catcagcctt taactgttcc
     2461 actaattggt caactgagtc aaatttggtc atatcacgaa tgcgatcaag ccaataaacc
     2521 atgacggttt ccccataaat atcttgatta aaatcaaaaa tattgacttc aaaacgtgct
     2581 tcttctccat caaaggtcac atttttcccg acactagcca tagcacgata cttctgtctt
     2641 tgaatctcaa catcaacgac ataaacgcca tctgctggca tataagtacg gtctaaaagc
     2701 actaaattcg ctgtcggata accaattgta cgaccacgag cattaccatg aaccaccata
     2761 cctcttgatg gaagcggtgc ccccaaaagt tttcctgctt ctttcacatt tccatctaaa
     2821 atagcttgac ggatacgagt tgaactaatc tttcctttct catcttctac aggtggaaca
     2881 atgataactt ctccatcaaa gtaatccttt aaatcttctg ctgttttttt gtcagaacca
     2941 aatgtataat caaaacctgc aacaataatt ttggcattca tagccttgat ataagttgca
     3001 aagaattctt gtgcagtgag actagcgaat tgactactaa aatcaaggag atataattct
     3061 tctacacctt cgcgctttaa ttttctttca cgttcagcag ggttcaaaat atgcaaaaac
     3121 aaatctggat gataaggctc taaagcgatc tttggagatt cattaaaggt cataacgacg
     3181 ataggtaata aatcctttct cgcagccttg ttggcaacac gaaataattc ttgatgcccc
     3241 ttatgtatgc catcaaaata gccgagaaca acgactgaat cagatggtgt gccaatatct
     3301 ttttggtttt ttataggaat agtaataatc ataaaataat tatatcatag cgatagctat
     3361 ttctggaaca gaaaatctga aatgttgttt ttttcacatg aagtgtacct gttttcaaaa
     3421 agcactttat tctatcgttg cttaactatg aactttgcaa tattcttctc aaaaacttgt
     3481 aggacatctt caaaattttg caaggagtga ttagacttgt tcggtaacca taaagtgtca
     3541 tactatgctt atgtatgaaa aagcaatgca actaactcct gagaacttta aattactaat
     3601 tggtgccgaa aaggtagaat ttagaatcga ggtacaccta tggctgtaaa atttacaaaa
     3661 tgagacaact tgggcaagat gtttgaagaa tttcctaaac tccctgattt gaagcaagtc
     3721 actttccctg atgacaaaga aaaaagccaa aacagcaaag aaaaactaga tgactgcttt
     3781 ccaacaactc ccatctagtg tgcttcagac taggctattt ttctctccat ctgttagctt
     3841 ggattctcag accgtttcag ctaaagaata tcttttccct tatcagaagg aacggctcaa
     3901 accattcaga caagtgaagg gacgacaagc caatatttga aaccagatag cagttcttat
     3961 agtcaattga aataaaatct gaagaaatcg agtaggaaac tcatatcaat ttttaacagt
     4021 gttctattcc agattcatac tcaatgaaaa ttaaagtgca aactaggaag ttagccgcag
     4081 gctgtacttg agtacggcaa ggtgaaactg acgtggtttg aatttgattt tcgaagagta
     4141 tcaatccact atacatatta aaaagtatgg atatcaaaac aaaaaaacag gctctccgaa
     4201 aactcggaaa gccttatttt aagctgtttc tagcttcctc acctttacat ttcaaggttc
     4261 gggataaaag gttcaatgga cctttttatt tagcgattgg gtaaacagaa acttgttttt
     4321 tatcgcgtcc tttacgttca aagcgtacta cgccttcaac tttagcgaac aaagtatcgt
     4381 ctccaccacg accaacgttt acacctggat agatatgtgt accacgttga cggtaaagga
     4441 ttgatccacc tgttacagtt tgtccgtcag ctgctttagc tccaagacgt ttcgcttgtg
     4501 aatcacgtcc gtttgatgta gaacctccac cttttttgtg ggcgaaaagt tgcaagttgt
     4561 taagagtcat ttttaacata atgttttcct ccgtgttagt tttctgtgat aactctggtt
     4621 tggacgaact cagaagagtt ctccgataag tttgccatac ctaagaaaaa tgattcaaag
     4681 aataactggg tcatttctct ctggtgtgaa ggaagatctt ttggtatttc aaccatcaga
     4741 tagccacctt catcttcgtt taattctagg attggttcat agcctgcaaa tttctcaata
     4801 gaattgataa agttaatggc aagcgtagaa accgatgcac acacgacatc taagccgtat
     4861 tcgccactct cggcgtgtcc agtaatttcc gcactcctca gctcgccatc ttcggctctc
     4921 tcaaagactg cctgtatcat gtgttctcct taaaattaag cgttgattgc gttgatgaca
     4981 acttttgtat atggttgacg gtgaccttgt ttacggtggc tacctttttt aggtttgtac
     5041 ttgtaagtaa ccactttctt ttgttttcct tgtttttcaa cagttccaac tacagtagct
     5101 ccagcaacaa gtggagttcc gacaacagtg ttttcaccac caacaagaac aacttcgtta
     5161 aaagtaactt cttgaccagc ttcaacgttc aatttttcaa cgtaaactgc ttgaccaact
     5221 tcaactttaa cttgttttcc gccagttttg ataattgcgt atgtgctcat tatgcacctc
     5281 ctatgatttt tatgggtttc cccgattttt tgtgaagact cgcctagcat cgtgggacga
     5341 accacttaaa cttgaataat caagcaacga tgttcgtgcg gttgcacagg atcgtgcata
     5401 gtcaactctt caagtatagc atatctccta ttttcttaca agtaataaca cctaaaatga
     5461 agctttttct tttacttttt tctgccaaga ggcaaaaagc atgctgaggt aaaaaacgct
     5521 catcataata ggaacaccaa gaatggtctt ttcatgatag aaaatcgtca aataggctga
     5581 aaagacaacg ccaaggacaa aactactaag caggctaaca aatatgaatc cttcacgcaa
     5641 aaaaggagtg tgcttggttc ggaaataatc tccaaaagcc agcatggtcc gtttgatatt
     5701 ccctgtcata aaagcgttat tataggcaat acccgacact tctccaaaag cagttgtcac
     5761 cagtcccata cagaaggcca agggcggcac tagatagata ttatccacag tttgcggcac
     5821 aaaagcaata atgattgata agattgccaa gggaatcaag gacagaatag gttttttcac
     5881 aattctcaat ttttccttat aaatcgttaa taaaaagact cccatcataa acgctagcaa
     5941 ggtgagaacc ttgtccctaa catccgaaac attattttta attaattcta ctgaaagaaa
     6001 gacaacattt ccagtttgtc cagctacaag ggtattcccg cgaacaataa aagtgtaagc
     6061 atccacatat ccagcacaaa acgtcaaaaa aagtgctaac cttttagact gacgtgatat
     6121 ttttcttata ggtaataacc tcattttacc tcccattgta ttttctctta gaaatattgt
     6181 accattttct ttctaaaaaa tcgtaggcta ccatttagat tttactatta gcataaaaat
     6241 aataatagac aactatttat ccaaaaatag atagatgtaa catgtttgca aacaaagcat
     6301 acgaaccttt agtaaaatca tttccatgaa actagaatag agccctctta gcaaaaatca
     6361 ttattttaat ttatttctaa tcactccttg acataaataa ctctcaccaa taaaagacta
     6421 tgtcttaaaa aaatggtata ataaaatcaa tacttgggct tgatggctat gctactaata
     6481 acaattagga gagaaaatca ggcacttgtt aacaacaagg attatcccct tgagatgaaa
     6541 ggaactttag aaatcttatg atgaacatgc aaaacatgat gcgtcaagca caaaaacttc
     6601 aaaaacaaat ggaacaaagc caagctgaac ttgctgctat gcaatttgtt ggcaaatctg
     6661 ctcaagatct tgtccaagcg accttaactg gcgataagaa agttgtcagc attgatttca
     6721 atccagctgt cgttgaccca gaggaccttg agactctttc tgatatgacc gttcaagcca
     6781 tcaactctgc tcttgaacaa atcgatgaaa ctaccaagaa aaaactgggt gctttcgctg
     6841 ggaaattgcc attctaaaaa caaggagcta gaacaatact tgtcgataac aaaggctaag
     6901 aaaggtgcaa aaattataaa aaacgcataa tagcaggtgt caagacactt aatattatgc
     6961 gttttctcat gaaaaaattc tcttttcata ctcatttaaa atcaaaaagg gaatttatcg
     7021 ttttacggac atgtatatta cagatttcta taggtcgtgt atagacagga tatcatcgct
     7081 tggaagtttt cctttttgac accaatcagt aatttagttc tcaggaatta atggcagtgc
     7141 ttttcgtaca tagtttcata actacagtat agcatagtat atcactttat agttttcact
     7201 attgatgaac tgcttgagct gctgtgatga gggtcaactt gtaaacatca tctgcattac
     7261 atccacgaga aagatcatta actggcttgt ttaaaccttg caaaacaggt cctacagccg
     7321 caaagccacc caggcgttca gccatcttgt aaccgatatt tcctgcctcg atacctggga
     7381 agatgaagac atttgcttga ccagctactg tacttcccgg agctttcaga gctgcagttt
     7441 cgggaacaaa ggccgcatca aattgcaact caccatcgat ttcaaggtca ggacgcaagt
     7501 cgtgagcaat tttagttgct tcaacgacct tatcaacgct ttcaccaaac cctgaacctt
     7561 tagtagaata gctcaacatg gcaattttag gttcgatgcc aaacatctta gctgtgattg
     7621 ctgagttgat ggcaatttca gccaaggctt ctgcatctgg attgatatta atggcacagt
     7681 ctccaaatag gtaacgttcc gtaccacgaa ccatgaggaa ggctcctgaa gtacgagtta
     7741 catttggacg agttttgatg atttgtagag ctgggcgaac tgttgaagct gttgagtgaa
     7801 tcgctcctga caccattcca tcaaccaagc ccaagtaaac caacatcaca ccaaagtagt
     7861 tgacatcttc aaccaaaacc ttgcgtacat cttcttcagt cattttgccc ttgcgacgct
     7921 ccaccaaggc agaaaccatt tcttcaaatt gaggataatg ttgagggtcg atgacctcat
     7981 aaccatccat gattccttca atttcaagat aaattttaat tttttcagga tttccaagca
     8041 aaacaggaat cacttctgtt tcttttacta agcgttttgt tgcttgaaga atacgaggct
     8101 cttccccttc agggagaacg atacgagcat ttttaccaac aaggttggct ttgagacttt
     8161 caaaaacttc catgagtttt ctcctttaag ataataatta tactctgaga cagtttttat
     8221 agagtattag ttgataactg ggtaataagg ttactgaaat catccggcaa gggactttct
     8281 aactgcaagt cttgctctaa aaatggatga taaaaggata ggtaatggca atgcagagcc
     8341 tgacgttgaa taccatcttc cagactacca ccatacaaat catctcccag caaaggaaaa
     8401 ccgatatgag aaaaatggac tcggatttga tgggttcgac cagtgtgcag gtgaatatag
     8461 accaagtgaa tatttccata agaagctaca atcttgtatg aagtatgggc atactttccg
     8521 cctttagcca ctcgtctggt aataatggaa tcttcatcac gcgcaatcgg agcaataatt
     8581 tccccttctg gctccaaatg tccatttccc ttaaccaaag caaagtagcg tttctcgata
     8641 gatttcttct gcaactgctt gtctaatcgt gcatgggcat aaccgtgctt ggcaaagagc
     8701 atcaagccag aagtgtccct atctagtctg gtaacaatgt gaacctgctg attttcataa
     8761 ttttgcttga catagtaacc cttgataaaa ttggcaatgg tattagagtg attgacacta
     8821 ggaatagaag ccactccata gggtttattc aagactagaa agtggtcatc ctcatagaga
     8881 atatctaatg gatgctcaat agcctccaag gtttcaaagc cttcctcagc gggaatgtaa
     8941 atggtaacgt agtctccaac gtccaataga tacgttgcat tttgcggttg attattgacc
     9001 agaatagctc cacctcgaaa cttaatcttg gccagcaatc ccttagaaac ctcgtgcttt
     9061 tttaaaaagg tcttaacctt gacatgttca tctgcgataa attcaaacct cattcatcca
     9121 cctcaccgat aaaggcatcc ttaacacggt tccagaaact ggtatggcta ggagtcgcga
     9181 caaagtgaat cttatgatgg tcgatttgat actcaatacg ctcaatatta cggaaagaat
     9241 aaacgctatt gtcaaccgaa atagtatgat aatcgtttct tgttggaata agttcaatct
     9301 tatccttctt aggcacaata atggaagagc ccaatgttcg atagacacga ttattaaggc
     9361 tggcaatctc cgttaattgc aaagcttcaa tggtagggtg taaaacagca ccgccaagag
     9421 acttgttata ggcagtacta ccagtcggtg tcgaaactgt tagcccgtct ccacgaaaac
     9481 gttcaaaggg aacaccattt attacaatat ctgccaccat ggttcgatca gacctgcgga
     9541 tgctggcttc gttgagtgct ctgaaaatct taacttcacc attttcgaga aagaccttca
     9601 cattcagaac agggtaagaa acccttgccc cagtatctag ctgcaaatta gtcactagct
     9661 tgtccaactc aaaatcacga taatctgtat agaagcccaa atgtccagta tgaagaccga
     9721 taaagcggac cttgtcaagc tgattttcgt acttatgaaa ggccgacaag agcataccat
     9781 ccccgccaat ggaaatgaca atatccggat tggtatcatt gagtataaac tgatttctct
     9841 tcaaacgatc tcgcaattca tacaaaaccc tttgactctg cggttttcta ttggctatca
     9901 gatcaattcg tttacctgta ttcttcatct gtatcgtcac tgtttcctac accgtcattt
     9961 aattttctac tcaaaggatc aaaaagtgcc tgggcttctt ggatatcatc acgaatttca
    10021 cccatttctt catccaactg atgggcgatt ctagctgtaa tttccagtcg cttcttaatc
    10081 tcatctggga aatccccttg gtacttgtag ttgagagaat gttctatcgt tgcccagaaa
    10141 ttcatggcca aagtacgaat ttgaatttct gccaaaatag tcttagctcc attgatggta
    10201 tcaaccgtat attctactac cacatgatag gaacgatagc ctgatgcttt tctatgagta
    10261 atgtaatctc gctcctgtat gattcgcata tcctgacgct tgtgcaaaat atccactact
    10321 tccttgacgt catctacaaa ctgaaccatc acacgtaagc cagcaatatc ctgcaaatcg
    10381 tgttccaagg tcgcataagt aatgccacga cgagccattt tttctttgat gctctcaatt
    10441 ggcttgactc gaccggtcac aaactcaatt ggagaatgct tattttgctt acgatattgc
    10501 ttacgaatac cacgaagttt aatctttaac tcaccaacag cttgaatgta aggatctaga
    10561 aattcttccc attctaaggt catatattct cccttgttct catattatcc gtcaaaaata
    10621 tctttgattt tttctccaga ttcatataca ataaatacaa tgcttattat accataaatc
    10681 cgctttcaac gataaaaaaa ggtaagaaaa atgaaacatt tagaaattga attgaaaata
    10741 ctattgaaaa aagatgaata caatcgtcta aaagaccagt tcacaggtgt cactcctgtt
    10801 cttcaaacaa attactacat cgacacgcct gattttgaac tgcgagaaaa gaaagtcgct
    10861 atgcgcattc gaacctttga agactgggct gagttgacac tcaaagtccc gcagagtgtt
    10921 ggaaacatgg aatacaacca aaaattgcaa ctaaaagatg ctgagaacta tctgagtaag
    10981 gaagaacttc ctcaagggct agtactggat gaattggcga aacatggtat ccaaagtaag
    11041 aactggcagg ttcttggttg tctaacaacg cttcgctatg aaatgaaaac agctattggt
    11101 ctcatggcac tggatcagag ccgatacttt gatataacag attacgaatt ggagcttgaa
    11161 gtggaaaatc atgagcaagg caaacaggat ttccgacaat ttttagagaa aaatcagatt
    11221 tcctaccaaa aagctccttc aaaattggtt cgatttgtca aaagtatgaa aaatagctga
    11281 aataatctcc attttttggt aaaatagaaa agataaaaat acacaaatcc cagttcatat
    11341 atgtaaggta aatataacta ggatttataa agtttacaga ggacggtcta taatgtcaga
    11401 tagaaaaaac atgaaacttt tcgcactcaa ctctaaccaa gagattgcac aaaaaattgc
    11461 ccaagctgtt ggtgtcccac ttggaaaact atcatcacgt caattttcag acggagaaat
    11521 ccaagtaaat atcgaagaaa gtgtccgtgg ttatgatgtt tacatcatcc aatcaacaag
    11581 tttccctgtc aacaaccacc taatggaatt gttaatcatg gtcgatgctt gtgtgcgtgc
    11641 aagtgcccac agtatcaacg ttgtccttcc atattttggc tatgcacgtc aagaccgcat
    11701 tgcttgtcct cgtgagccac ttacagcaaa actagttgcc aatatgctgg ttaaggctgg
    11761 agttgatcgt atcctgactc ttgatttgca tgccgttcag gttcaaggtt tctttgatat
    11821 tccagtggat aatcttttca ctgttcccct attcgcaaaa cattactgcg ataaaggatt
    11881 gcttggttca gatgttgttg tcgttagccc taaaaattca ggtgtcaaac gtgcgcgtag
    11941 cctggctgaa tatcttgatg ctcctatcgc cattatcgac taccctcaag acgatgcaac
    12001 tcgtaacgaa ggttatatta ttggtgatgt tgaaggtaag aaagctatct tgattgatga
    12061 tattttaaat acaggacgta ccttctctga agcttctaaa atcgttgaac gtgaaggagc
    12121 tacagaaatt tatgctgttt ctagccacgg tctcttcgtc gagggagctg ctgagcttct
    12181 tgacaatact aatattaaag aaattcttgt gactgattca gtagcaacaa aagaaaaaac
    12241 tcctaaaaat gtatgctaca tcactgctag tgagttaatt ggtgatgcta tcgtccgtat
    12301 tcacgaaaga aaaccagtca gcccactctt tgcctacaat aaaaagaaat aaggtgattc
    12361 tttgatttat ttggacaatg ctgcaacgac tcctatgtca gcagttgcta tttcagctat
    12421 gaccaaggtt atgcaagaaa cccacggaaa tccttctagt attcatggtc atggtcgtca
    12481 agctggcaaa ctcttgcgag aagcccgtca ggaactagcc cagttactaa ggacaaaacc
    12541 tcaacatatc tttttcactt ctggtgggac tgaaggcaat aatactacca tcattggcta
    12601 ctgtcttcgt caccaagaac aaggaaaaca tatcatcaca actgccatcg agcaccatgc
    12661 tgtccttgaa acaattgatt acttggttca acactttggg tttgaagcaa ccattatcca
    12721 gccagaaaat caagaaatca cagcccagca aattcaaaag gctttacgtg acgatacgat
    12781 tttggtttct accatgtttg ccaataatga gacaggaaac ctactgccca tcgctgaaat
    12841 tggccaaata ctcaagcaac accctgctgc ctatcatgtt gatgcagttc aggctattgg
    12901 taaaatccca attcattcag aagaattggg cattgatttt ctcactgctt ctgcccacaa
    12961 attccatggt cctaagggaa tcggttttct ctacgcatct agcatggact ttgattccta
    13021 tctacatggc ggagaccagg aacagaaaaa acgtgcagga actgaaaatc tgcctgctat
    13081 cgtaggcatg gttgcagccc taaaagaaga cctagaaaaa caagaagaac attttcaaca
    13141 tgtacaaaat ctagaaactg cctttctggc agagctggag ggtattcagt attacctgaa
    13201 tagaggaaaa catcatctcc cttatgttct caatattgga tttcctggtc agaaaaatga
    13261 cctcttactc cttcggctag atttagctgg aatttcaatc tctactggct cagcctgtac
    13321 tgcaggcgtt gtccaatcca gccatgttct taaagccatg tatggcgcaa attcagaacg
    13381 cttgaaggaa tcccttcgca tcagtttgtc gccacaaaat accgttgaag acctacaaac
    13441 cctcgcaaaa accttaaaag aaattatcgg aggttagcca tatggcattt gaaaaaatca
    13501 ttcagttaaa aaattgtcgt tacgattaca ctcttagccc ttctgttaaa aaattcaccc
    13561 tcaaagataa cacctttttt gaaactaagg ttggtaacta tgaactgact cgccttttgg
    13621 aaaaagtgcc aaacagcggt gaaggcttcc aactcaaaat catcattaac aaggaactta
    13681 caggggctaa aatcaatatc actgacaagt ttggccttcg tctagttgat attttcaaat
    13741 cagaagacca ccatattcat caggaaaaat tctacttcct catggatagc ttggtagaac
    13801 gtggtgtctt tacaaaatcg gaaagataga gccaaaatgt ttgaactgac ctataaggac
    13861 tgctatcatg tagagcgtac tctcaagtat gaggatcatg aggctctcat gttgactttg
    13921 tcaggatgtg taaccttacc agatacactt tatgtgactt ctctgacttt taggggcaaa
    13981 aaagtttatc aggggctggt cggagacctc taccgttttc tatctcatgc agatttttta
    14041 catcaaaact aagatttttc ttagtttttt cttatttttg ttgatttttt cacaatgttt
    14101 ctataaaata gaagaataga aaggttgtga ttttgtgaaa gataaacagt ttgctattcc
    14161 aaaagctaca gcaaaaagac tctctctcta ctatcgaatt tttaagagat ttcatgcaga
    14221 aaagattgaa cgtgccaact ctaagcaaat tgcagaggct atcggtattg attcagcgac
    14281 cgtacgtcgt gatttttcct attttggtga acttggtcgt cgtggttttg gctatgatgt
    14341 caaaaaacta atgacatttt ttgccgattt gctcaatgac aactctatta ccaatgtcat
    14401 gctggttggt attggaaata tgggccatgc ccttctccac taccgcttcc acgaacgtaa
    14461 caagatgaag attatcatgg cctttgacct agacgaccat cctgaagtcg gtacccaaac
    14521 tcctgacggg attcccattt acgggatttc tcagatcaag gataaaatca aggatgctga
    14581 tgtgaagact gctatcctaa ctgttcccag cgtcaagtca caagaggttg ctaatctctt
    14641 ggttgatgct ggtgtgaaag gaattctcag tttttcacca gtccatctgc atttaccaaa
    14701 agacgtggtc gttcagtatg tcgatttgac aagtgaactc caaaccctcc tctacttcat
    14761 gcgaaaagag gattagaaag cgaaaatcat tttatgaaaa aaccagttat tgggattaca
    14821 ggaaacgaaa aaactcatcc agatgatgac atcatgatga gctacgcagc aaaaggcttt
    14881 gttgaaggcg ttaaagatgc tggagggatt cccatcatcc taccgattgg tgatcaagaa
    14941 atggcctgcc actatatcag tttgattgac aagctcatct tgacaggtgg gcaaaatgtc
    15001 gatccaaaat tttatggcga acccaaaacc attgatagtg atgactatca ccttcaaaga
    15061 gatatcttcg aactggccct catcaaggaa gctattaaac agaaaaagcc cattttctct
    15121 gtctgccgtg gtacccaact ctttaacgtt gccatgggtg gaactttgta ccaagatatc
    15181 gaagaccatt ggcaggattc ttctgttgag tacacaactc aacgcttggt aacagaacca
    15241 gataccgttc tccaagaaat ctatggagaa atctctcata tcaactcctt ccaccaccag
    15301 agcatcaagg acttagcacc aaatttaaaa gttgtggctc atgatcctaa agatggtatc
    15361 attgaggctg tcatgagtac ggatgatgtc gcctttctcg gtgtccaatg gcatccagaa
    15421 cttctttttg aaaatcgtcc caaagataaa aaactctttg actatgtcgt taatgaactt
    15481 tagattaaat ctgtcttttc acgataacta aagtaattag aatgagagac aatcaaatgg
    15541 tccaagagaa caatccccat caattcgcag gcttctttaa caagtttagt gacatgatca
    15601 tcattttggc taggcgctac cgctcctgaa ggatgattgt ggaccaagat aagagaagtc
    15661 gccatatgct tgattgcata gtgaagaatc tctcgcggtt cagcgatact acgagttaca
    15721 gacccgataa aaatggtctg ctgatggatg atttgatttt gagtattgag atagagtgcc
    15781 accaggtgct cttgtttttt atcccctaat tcctgctgca tcttcttggc caacttttga
    15841 ctgctgagaa tactttccat ttcaagagtc tcgtgtttgt gaatacgatg ccccagttca
    15901 atcatagctt gtaattctat ggccttaaca cgcccaatac cagacaaact ctgcaattcc
    15961 tgcagggtca tttttttcaa atccgttagg cttgaaagat tgttcaagac tttttgggca
    16021 atttcaaaaa cgctagcttg acgtgttcct gtcctgagta aaatagctag caactcttgg
    16081 ttactaagcg cttcaactcc ttccttggcc agcctttctc ttggtaatag tgaatcttct
    16141 tggaatgaaa tactgtacat aaaaatcctc ctcactttat tattcgtgag aaggatggaa
    16201 aattagattt ttttctcaat tggagccaca ctggctaaaa gttttttcaa acctacttct
    16261 gggaaattga ttttcaattc ctgcctagca ccgctacctg aaacttccag aacggttccc
    16321 tctccccatt tcttgtggag agcaatatca ccaatggacc aatttgcctc gctagatgct
    16381 ggttttgcgc cagctgtaaa ttgaccaaat ggaagaccgc ttgactggat tgattttggg
    16441 gcagcaccgc gtttacggtc ttgaagagcc tgagccaaac tcataccttg accaaaggaa
    16501 atactaccac tgctatatga tgccttaaag cttgtatttg caggacgagc cagaccttga
    16561 tactcaagca agtctgaact gatttcgtta ataaaacgag tcggacggtt ataattggta
    16621 cgaccaaaaa gcaagcgtga gttggcattg gtcagataga gaattttctc tgcacgcgtg
    16681 atacctacat aggctagacg gcgctcttct tctaattcat ctgaatcttc agtcgcacga
    16741 ctaagtggaa agacattttc ttccatccca atcaaaaaga caactggaaa ttcgagacct
    16801 ttggcagcat gcagggtcat caaggtcact tctgatgtct cctgactacc tgaatctgtg
    16861 tcggcaatca aagccaagtc atttaagaaa cgactcagtt tgtccagacc agtttcctct
    16921 tctgtcacat ccgtggtgtc atcaaagttc ttcgtaacag aaagaaactc ttcgatattt
    16981 tcaacccgtg ccttgctttc tagagtcgct tgggcgttaa gaatatcgac ataacctgtt
    17041 ttttctagga cggactcaac caactctgta atgcttaagt ggtctagctg ctcccgcaaa
    17101 tcaagcatca tattggcaaa atcccagata gattgggctg tcttaccctt gataccagac
    17161 aacataatat tagcagaagc atccagcata gacatatttt gcaaatttgc aaaatcacgg
    17221 attttctcaa ctgtacctgg accaattcca cgtttaggct cgttgataat acgctcaaaa
    17281 ctaatattgt cactcaaatt agcaataagg ttgagataag caataatatc gcgaatttcc
    17341 ttacggctgt agaatttggt tccgccaacc atggtataag gaatgttaga cttgagcagg
    17401 gcttcctcaa ttgtacggga ctgggcatta gtccgataga gaactgcaaa atccttatga
    17461 aggaagtttt gactgcgact aagttcatcg atggttctgg ctacaaatac agcctcatcc
    17521 agctcatcat cggcacgata gtaaacgatt tgctccccat cagcgttttg agtccagaga
    17581 tttttaggac ggcgattttt attattttta ataacctcgt tggccgcttg gagaatggtt
    17641 ttggttgagc ggtaattttc ctccaacaaa acaaccttag ctttggggta atccttttca
    17701 aagtccaaga tattctgcat atcagcacca cgccaaccgt agatagactg gtccgcatcc
    17761 ccaaccacac agatattttt aaaacgggaa gccaagagtt tgaccaattg gtactgagcg
    17821 tggttggtat cttggtactc atcaacgtgg atgtattgga atttttgctg gtagtaggtc
    17881 aaaacatcag gattttgatc aaagagacgc aaggtcagca taatcaaatc atcaaagtca
    17941 acggattcag actgacgaag ttctttttga taggctgtat aacactgggc cacaatttgc
    18001 gtatacatat cgccagcttg ggcagcataa gcaacatcat caatcaaatc attcttagca
    18061 ttggaaatgg tccccaaaat agttcgttca ttccattttt taggatccaa gttcaactgt
    18121 ttgagaatac gtttcatgag cgttcgctgt tcaccaggat ccacaattgt aaaattacga
    18181 ttgtagccaa tatggtccgc atcgcgacgc aaaatacgca cacacatgga gtggaaggtc
    18241 gcaatcagac agtcctgagt cgctggattg aggctataag cacgctcttt catctcacgc
    18301 gcagccttgt tggtaaaggt aatggccaag atattccaag gattgaccag cttttcatca
    18361 atcaaataag cgatacggtg ggtcaaaaca cgagtctttc cagaaccagc ccctgccatg
    18421 attagcaagg gaccttctgt cgtttgcacc gcctcagcct gacggtcatt cattccattt
    18481 aataatgcgt tcatcttctc ttccttactc ttgaagtcaa tatttctatt atatcagaaa
    18541 tcagggaaaa tagaaacttt acggggagta gcaaaatata gtggattgaa actagaatac
    18601 tacactgtgg gtttctaaaa cactcgactt ttcacccaat tttttcataa actagctcaa
    18661 tacctcaata gacttcctgc aaaacta
//
LOCUS       DBEJAU010000045        16952 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC323 isolate 683620
            SAMN38261939-rid24807223.denovo.045, whole genome shotgun sequence.
ACCESSION   DBEJAU010000045 DBEJAU010000000
VERSION     DBEJAU010000045.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261939
            Sequence Read Archive: SRR26833919
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 16952)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16952)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576303.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576303.1
            Genome Coverage       :: 154x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/19/2025 01:05:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,121
            CDSs (total)                      :: 2,078
            Genes (coding)                    :: 1,943
            CDSs (with protein)               :: 1,943
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 36
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 72 of 135
            Pseudo Genes (incomplete)         :: 63 of 135
            Pseudo Genes (internal stop)      :: 51 of 135
            Pseudo Genes (multiple problems)  :: 46 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16952
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261939-rid24807223.denovo.045"
                     /strain="GPSC323"
                     /isolate="683620"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            complement(492..707)
                     /locus_tag="ACL29Z_001629"
     CDS             complement(492..707)
                     /locus_tag="ACL29Z_001629"
                     /inference="COORDINATES: protein motif:HMM:NF012920.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S24 family peptidase"
                     /protein_id="HGR0069908.1"
                     /translation="MEPKIRNSDYLFIKNTPQIDYNTIGIFQVDGTNYVKKLRQGCLK
                     KTQSRIPRHPPRRKQPYSYHRESCQAI"
     gene            complement(1066..1119)
                     /locus_tag="ACL29Z_001630"
                     /pseudo
     CDS             complement(1066..1119)
                     /locus_tag="ACL29Z_001630"
                     /inference="COORDINATES: protein motif:HMM:NF013540.4"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="XRE family transcriptional regulator"
     gene            1555..2427
                     /locus_tag="ACL29Z_001631"
     CDS             1555..2427
                     /locus_tag="ACL29Z_001631"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000749590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4300 family protein"
                     /protein_id="HGR0069909.1"
                     /translation="MKKSRKLATLGICSALFLGLAACQQQHATSEGTNQRQSSSAKVP
                     WKASYTNLNNQVSTEEVKSLLSAHLDPNSVDAFFNLVNDYNTIVGSTGLSGDFTSFTH
                     TEYDVEKISHLWNQKKGDFVGTNCRINSYCLLKNSVTIPKLEKNDQLLFLDNDAIDKG
                     KVFDSQDKEEFDILFSRVPTEATTDVKVHAEKMETFFSQFQFNEKARMLSVVLHDNLD
                     GEYLFVGHVGVLVPADDGFLFVEKLTFEEPYQAIKFASKEDCYKYLGTKYADYTGEGL
                     AKPFIMDNDKWVKL"
     gene            complement(2573..2917)
                     /locus_tag="ACL29Z_001632"
                     /pseudo
     CDS             complement(2573..2917)
                     /locus_tag="ACL29Z_001632"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0032196 - transposition [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase family protein"
     gene            3060..3371
                     /locus_tag="ACL29Z_001633"
     CDS             3060..3371
                     /locus_tag="ACL29Z_001633"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007521917.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0069910.1"
                     /translation="MELKDFTEKEQEMIKKRLTMSNISDKETTEKILALVPQDLIKRI
                     PFFVRKHATTRTIKRISIEHPELYAVAQTSGEIPEKKREELRQIITTIFEQKMNKHSI
                     K"
     gene            3375..4091
                     /locus_tag="ACL29Z_001634"
     CDS             3375..4091
                     /locus_tag="ACL29Z_001634"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000759776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HGR0069911.1"
                     /translation="MKKYFIGGLGSDAYHSKDFLQELDSQVYFLNPYEKHLRDETELK
                     LWFKNEIVEEESICLIGHSIGGDLARYFASEFEEVKKLILLDGGYLDLDKILPLDTEL
                     EETKNYIKSQIISDLDVLTSKEKSEAKHWSENMEKAVRQSYHWNVEYNRYELAINYEN
                     IEAILRLRRKIQAFKREVGDTLFISPRYPNEATWREEALKELPDYFDTIFLENFGHEL
                     YTQAPKEIASLMNEWLAYFL"
     gene            complement(4220..5035)
                     /locus_tag="ACL29Z_001635"
     CDS             complement(4220..5035)
                     /locus_tag="ACL29Z_001635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000617844.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR03943 family protein"
                     /protein_id="HGR0069912.1"
                     /translation="MIRFLVLAGYFELTIYLHLSGKLNQYINMHYSYLAYISMVLSFI
                     LAIVQLYIWMKQVKTHSHLNSRLAKMTSISLLAIPLVIGLTFPTVSLDSQTVSAKGYH
                     FPLSEGTDLAIQTSEGTTSQYLKPDTSSYFSKSAYEKEMRTAADKYLSQDSIQITNEN
                     YMEVMEAIYDYPDEFEGKTIQFTGFVYNDPSHANSQFLFRFGIIHCIADSGVYGLLTK
                     GNTRQYENNTWITAKGKLVNHYHKELKQNLPTLEIDSFTKVDKPENPYVYRAF"
     gene            complement(5032..5937)
                     /locus_tag="ACL29Z_001636"
     CDS             complement(5032..5937)
                     /locus_tag="ACL29Z_001636"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="permease"
                     /protein_id="HGR0069913.1"
                     /translation="MTAFQQLPSSVLQTGAIFLSIIIEALPFVLIGSIVSGLIEVYIT
                     PDKVYHFLPRNRWGRIFFGTFVGILFPSCECGIVPIINRFLEKKVPSYTAVPFLVTAP
                     VINPIVLFATYSAFGNSFHVALLRALGSILVAVILGIFLGFFWQEPIQKENRLACHEH
                     DFSYLSSAKKVFQVFVQAIDEFFDTGRYLVFGCLFASIIQVYVPTRILTSISATPLFA
                     ILLLMLLAFLLSLCSEADAFIGASLLSSFGLAPVLAFLVIGPMLDIKNILMMKNYLKA
                     RFISHFITIVTLVVLAYSLLIGVIL"
     gene            complement(5938..6069)
                     /locus_tag="ACL29Z_001637"
     CDS             complement(5938..6069)
                     /locus_tag="ACL29Z_001637"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004245481.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPJ_0845 family protein"
                     /protein_id="HGR0069914.1"
                     /translation="MAVKFTKRDDLDKMFEEFAKLPDLKQVTFPDDKEKKVKAEKKN"
     gene            complement(6183..6341)
                     /locus_tag="ACL29Z_001638"
     CDS             complement(6183..6341)
                     /locus_tag="ACL29Z_001638"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0069915.1"
                     /translation="MKIKKQTRKLAAGCSKYCFEVVDKTDEVSSKHCFEVVDRTDEVS
                     NRTTVRRS"
     gene            6394..8523
                     /locus_tag="ACL29Z_001639"
     CDS             6394..8523
                     /locus_tag="ACL29Z_001639"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000359105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005829 - cytosol [Evidence IEA];
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0003729 - mRNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Tex family protein"
                     /protein_id="HGR0069916.1"
                     /translation="MDKKYEKISQDLGVTLKQIDTVLSLTAEGATIPFIARYRKDMTG
                     SLDEVAIKAIIDLDKSLTNLNDRKEAVLAKIQEQGKLTKELEEAILVAEKLADVEELY
                     LPYKEKRRTKATIAREAGLFPLARLILQNIVDLEKEAEKFVCEGFATGKEALTGAVDI
                     LVEALSEDVTLRSMTYQEVLRHSKLTSQAKDESLDEKQVFQIYYDFSETVGTMQGYRT
                     LALNRGEKLGVLKIGFEHATDRILAFFATRFKVKNAYIDEVVQQSVKKKVLPAIERRI
                     RTELTEKAEEGAIQLFSDNLRNLLLVAPLKGRVVLGFDPAFRTGAKLAVVDATGKMLT
                     TQVIYPVKPASARQIEEAKKDLADLIGQYGVEIIAIGNGTASRESEAFVAEVLKDFPE
                     VSYVIVNESGASVYSASELARQEFPDLTVEKRSAISIARRLQDPLAELVKIDPKSIGV
                     GQYQHDVSQKKLSESLDFVVDTVVNQVGVNVNTASPALLSHVAGLNKTISENIVKYRE
                     EEGKITSRSQIKKVPRLGAKAFEQAAGFLRIPESSNILDNTGVHPENYAAVKELFKCL
                     DIKDLNEEAQSKLKSLSVKEMAQELDLGPETLKDIIADLLKPGRDFRDFFDAPVLRQD
                     VLDIKDLVVGQKLEGVVRNVVDFGAFVDIGIHEDGLIHISHMSRKFIKHPSQVVAVGD
                     LVSVWVKKIDTEREKVNLSLLAPNETD"
     gene            8510..8959
                     /locus_tag="ACL29Z_001640"
     CDS             8510..8959
                     /locus_tag="ACL29Z_001640"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000778579.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SprT family protein"
                     /protein_id="HGR0069917.1"
                     /translation="MKLTDYVKQVLLEDFGRPFIHHVQWNRRLRSTGGRFFPKDGHLD
                     FNPKVYQELGLDVFRKIVRHELCHYHLYFQGKGYQHKDRDFKELLKAVDGLRFVPSLP
                     NSNSKPIKLYRCQSCQQTYQRKRRIDTRRYRCGLCRGKLLLINQPED"
     gene            9018..9290
                     /locus_tag="ACL29Z_001641"
     CDS             9018..9290
                     /locus_tag="ACL29Z_001641"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PspC domain-containing protein"
                     /protein_id="HGR0069918.1"
                     /translation="MNSKFYKMRRNCMISGVLAGLSDKWNFDVTLVRFLFAIFTVANF
                     GLGVIIYIILASIMPTKEEIEAEMYGTGPRKRKEAQAIDDNEGWFW"
     gene            complement(9644..9835)
                     /locus_tag="ACL29Z_001642"
     CDS             complement(9644..9835)
                     /locus_tag="ACL29Z_001642"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000680763.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0069919.1"
                     /translation="MKHKEHILIGFLYLLSPFIGQLLVEHTHFIGTEFTGTAYVICWL
                     SVVISIHHFSKNVLSQQQK"
     gene            10263..11021
                     /locus_tag="ACL29Z_001643"
     CDS             10263..11021
                     /locus_tag="ACL29Z_001643"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000173375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGR0069920.1"
                     /translation="MTLLDVKHVQKIYKTRFQGNQVEALKDIHFTVEKGDYVAIMGES
                     GSGKSTLLNILAMLDKPSRGQVYLNGTDTATIKNSQASSFRREKLGFVFQDFNLLDTL
                     SVKDNILLPLVLSRRPITEMMKKLVMTAENLGINQLQEKYPYEISGGQKQRVAVARAI
                     ITEPEILLADEPTGALDSKSSAALLDVFNEINERGQTILMVTHSTAAASRAKRVLFIK
                     DGILYNQIYRGEKTERQMFQEISDTLTVMASEVN"
     gene            11023..13011
                     /locus_tag="ACL29Z_001644"
     CDS             11023..13011
                     /locus_tag="ACL29Z_001644"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000489335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HGR0069921.1"
                     /translation="MFRLTNKLAVSNLIKNRKLYYPFALAVLLAVTVTYLFYSLTFNP
                     KIAEIRGGTTIQATLGFGMFVVTLASAIIVLYANSFVMKNRSKELGIYGMLGLEKRHL
                     ISMTFKELVVFGILTVGAGIGIGALFDKLIFAFLLKLMKLKVELVATFQTKVVITVLV
                     VFGLIFLGLMFLNALRIARMNALQLSREKASGEKKGRFLPLQTILGSISLGIGYYLAL
                     TVKDPLTALTTFFIAVLLVIFGTYLLFNAGITVFLQILKKNKKYYYQPNNLISVSNLI
                     FRMKKNAVGLATIAILSTMVLVTMSAATSIFNSSESFKKVLNPHDFGVSGQNVEKEDL
                     DKLLSQFASDKGYKIKEKEVFRYTYFAVANQEGTKLTIFEKGQNRVQPKTVFMVFDQK
                     DYENMTGQKLSLSGNEVGLFAKNEGVKEQKALTLNDHQFSVKEEFTKDFIVNHVPNQF
                     NILTADYNYLVVPDLQAFLDQFPDSAIYNQFYGGMNVNASEAEQLKVAEEYEKYLQKF
                     NAQLNTEGSYVYGSNLADASAQMSALFGGVFFIGIFLSIIFMVGTVLVIYYKQISEGY
                     EDRERFIILQKVGLDQKQIKQTINKQVLTVFFLPLLFAFLHLAFAYHMLSLILKVIGV
                     LDTTMMLIVTLSICAIFLIAYVLIFMITSRSYRKIVQM"
     gene            complement(13054..13728)
                     /locus_tag="ACL29Z_001645"
     CDS             complement(13054..13728)
                     /locus_tag="ACL29Z_001645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003025968.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VIT family protein"
                     /protein_id="HGR0069922.1"
                     /translation="MDSNFAGRLNILRAGVLDANDGIISIAGVVIGVASATSNIWIIF
                     LSGFAAILAGAFSMAGGEYVSVSTPKDTEEAAVSREKLLLDQDRELAKKSLYASYIQN
                     GEFKTSAQLLTNKIFLKNPLKALVEEKYGIEYEEFTNPWHAAISSFVAFFLRSLPPML
                     SVTIFPSDYRIPATVLIVGVALLLTGYTSARLGKAPTKTAMIRNLAIGLLTMGVTFLL
                     GQLFSI"
     gene            complement(13724..14599)
                     /locus_tag="ACL29Z_001646"
     CDS             complement(13724..14599)
                     /locus_tag="ACL29Z_001646"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001153874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HGR0069923.1"
                     /translation="MQDNYTTKAKHLTIDSRRLIERWKKEGKSNREIASLLGKAPQTI
                     HTEIKRRTVRKCLGKGRFKEVYSADYAQQSYENNRKHSVKKSSLTKELKEKILHYHNQ
                     KFSPDKKQASTNFKPAGQSIEQRSEAINLRLENGYYEIDTVLLTRAKNYCLLVLTDRK
                     SRHQIIRLIPNKSAEVVNQALKLILKQHKILSITADNGTEFNRLFDVFSEEHIYYAHP
                     YASWERGTNENHNRFIRRWLPKGTKKMTPKEVAFIEKWINNYPKKCLDYKSPREDFWM
                     ANLNLKFSVRNKSRN"
     gene            15306..16781
                     /locus_tag="ACL29Z_001647"
     CDS             15306..16781
                     /locus_tag="ACL29Z_001647"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000661022.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016831 - carboxy-lyase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase class I/II-fold pyridoxal
                     phosphate-dependent enzyme"
                     /protein_id="HGR0069924.1"
                     /translation="MKELDQNQAPIYEALVKLRKKRIVPFDVPGHKRGRGNPELVELL
                     GEKCVGIDVNSMKPLDNLGHPISIIRDAEELAADAFGASHAFLMIGGTTSSVQTMILA
                     TCKAGDKIILPRNVHKSAINALVLCGAIPIYIEMSVDPKIGIALGLENDRVAQAIKDH
                     PDAKAILINNPTYYGICSDLKGLTEMAHEAGMMVLVDEAHGAHLHFTGKLPISAMDAG
                     ADMAAVSMHKSGGSLTQSSLLLIGEQMNPEYVRQIINLTQSTSASYLLMASLDISRRN
                     LALRGKESFEEVIELSEYARHEINAIGGYYAYSKELIDGVSVCDFDVTKLSVYTQGIG
                     LTGIEVYDLLRDEYDIQIEFGDIGNILAYISIGDRIQDIERLVGALADIKRLYSRDGK
                     DLIAGEYIQPELVLSPQEAFYSERKSLTLDESVGQVCGEFVMCYPPGIPILAPGERIT
                     REIVDYIQFAKERGCSLQGTEDPEVNHINVIKRKTNYKKSQ"
     gene            complement(16747..>16952)
                     /locus_tag="ACL29Z_001648"
     CDS             complement(16747..>16952)
                     /locus_tag="ACL29Z_001648"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001841243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0069925.1"
                     /translation="TYQLLTRYPNPQKRIEAGFDKLIEIKRLTASNSRAFCRALKSSP
                     NHQIEIRNSLDKTIDFSYSLSFS"
BASE COUNT         5120 a         3131 c         3528 g         5173 t
ORIGIN      
        1 aaataagata tgcacaaatt gattagaaag tcaaatgaat ttctacaaat gttttagcaa
       61 tcgcaatcta cttgtctaga ttcgatctga tatattttcg atttaatgat atggtattta
      121 aaacctccaa agtagcttgc tccattcttt tacttacgtg agtgtagatg ttatttactg
      181 ttttagcgtt tttgtgttcc actctaacca ttatagcatt cttctcagct agtgtactaa
      241 ggagtatgtg cctgaaaata tgggaactaa ggggctggtt tatcggtttc tctagtttag
      301 tatttgcctt ttgcaaagtg atgttaaatg cctttctcta aatttacata tcactattgt
      361 ttaacaaaat ctaatctact ttaggtcact tattcttttt ttgaaatgta gaatgaactt
      421 tttcaaagtt tttcgaatct tttaaaatct gtttgcttta tatcgccatt ctcccccttt
      481 tttaattctc cctatatagc ctgacagctt tcccgatggt acgaatatgg ttgctttcgt
      541 ctaggtggat gtcggggtat tcgggattga gtttttttga ggcagccttg gcggagtttc
      601 ttgacatagt tagtgccgtc tacttggaag atgccgatgg tattatagtc aatctgtggg
      661 gtattcttga taaataggta gtcgctgttt cttatctttg gctccatgga cttgctgacg
      721 acataagcga ttgggtcgta gtcgtctggg ataatggaaa ctccataact aaatcgtcgt
      781 cctgcatcga gcggctacct gcagagataa actacctaac acgagagtaa gtagtctgtc
      841 tgtagtcgtc cagtctgatg atttttacga tatttcgttt ttctgctcat acagttgcct
      901 ctcggcatag gtcaggactt taccttgtct gggtggtgcc cgttggtcgt agatagattg
      961 gatatcgcta ggagaatcct tttgaactgg aggaaagagg gtatcaatca agctactgaa
     1021 tactttagct aagtcaaata tagtattttt cttagtagac ctaacccttt tttcataatt
     1081 tccaatggtg tttttactta taccaatctt agtacccaat tcttattgag tccaaccatt
     1141 actagtctat attgttttat agttgattga gtttggaata gtacgctgta gctgctaaaa
     1201 catttctagg aattaatttg actttcctaa tagagttgtt catatcttat ttcaatctac
     1261 tatgtttttc acctctaaca atcgcaatct cttctttatc catgaatgaa atcgctttct
     1321 atttttgtaa gtaaagcatc acacgaaatc cacgaaaatg aaaacctttg ttgtgttttc
     1381 gtaaaaaatt tgttgacaga gcacgaaatg cctactataa ttaaatcaag cttaaggaaa
     1441 taacaaaaaa acaaatcgga gggaaagacg atgaactcat taaatgagaa agtaatcaat
     1501 atctgtaaag cagtagttaa agaaacttta atccaagaca tttaggagaa agaaatgaag
     1561 aaatcaagaa aattagccac attaggaatc tgttcagcct tgtttttagg cttggctgct
     1621 tgtcaacaac aacatgctac ttctgagggg acgaatcaaa ggcaaagcag ttcagcgaaa
     1681 gttccatgga aagcttcata caccaaccta aacaaccagg taagtacaga agaggtcaaa
     1741 tctctcttat cagctcactt ggatccaaat agtgttgatg cattttttaa tctcgttaat
     1801 gactataata ccattgtcgg ctcaactggc ttatcaggag atttcacttc ctttactcac
     1861 accgaatacg atgttgagaa aatcagtcat ctctggaatc aaaagaaggg cgatttcgtt
     1921 gggactaact gccgtatcaa tagctattgt cttttgaaaa attcagtcac cattccaaag
     1981 cttgaaaaga atgaccaatt gcttttccta gataacgatg cgattgataa aggaaaggtc
     2041 tttgattcac aagataagga agagtttgat attctatttt cgagagttcc aactgaggca
     2101 actacagatg tcaaggttca cgctgaaaag atggaaacat tcttctcaca atttcaattc
     2161 aatgaaaaag ctcgaatgct gtctgtagtc ttgcacgaca atctggatgg cgagtatctg
     2221 tttgtaggcc acgttggggt cttagtacct gctgatgacg gtttcttatt tgtagagaaa
     2281 ttgactttcg aagagcccta ccaagcgatt aaatttgcta gtaaggaaga ttgctacaag
     2341 tatttaggca ccaagtatgc ggattataca ggcgagggac tggctaagcc ttttatcatg
     2401 gataatgata agtgggttaa actttaatag tgttatgata tgacagtaat cttaggattt
     2461 ttatttctat ttttgatgac ttggtgggtt atttcaatcg ttaatagcca gaaaccacgc
     2521 aaaaatgaaa catttattgg ctatatccaa agatacgata ttgatgggaa tggctatcaa
     2581 tcattaccgt gtcctcagaa ctgagaggag ttcttgaaat cgtaaaacta ctttgaacaa
     2641 gagttacttc aacccattgg ctccgacgga ttaagttgct ttcgtgaaca ccaaaatcag
     2701 ccgcaatttc ttcataagtg cggtattctc gcacatattg aagagtggcc ataagaaggt
     2761 cttctaggct taatttaggt tttcgtcccc cttttgtgtg tttaagttga taagcagttt
     2821 ttaatacagc taacatctct tcaaaagtgg tgcgctgaac accaacaaga catttaaatc
     2881 gtgcatcagt tagttgctta cttgcttcat aattcataga actactatac catattttgt
     2941 ttcgcaggaa gtctaatgct aaaatcttat cagtgagaag atttcttaaa gtttattctt
     3001 tgtagtttca tctgtattag tacataattt aacttagaga aaataggagg actaatcgaa
     3061 tggaattaaa agattttaca gaaaaagaac aggaaatgat taagaaaagg cttacaatgt
     3121 ctaatattag tgacaaagaa actactgaga agattctggc gctagtacca caagacttga
     3181 ttaagcgaat cccgtttttt gtcagaaaac atgctacaac acgtacgatt aaacgcattt
     3241 caattgaaca ccctgaactc tacgctgtag ctcaaacaag tggtgagatt ccagaaaaaa
     3301 aacgcgaaga attgcgtcag attatcacaa ctatctttga acaaaagatg aataagcata
     3361 gtattaagta gagaatgaaa aaatatttta ttggcggttt gggaagcgat gcctatcata
     3421 gcaaggattt tcttcaagaa ctagattcgc aggtctattt tctaaatcca tatgaaaagc
     3481 atcttcgaga tgaaacagaa ttgaaattat ggtttaaaaa tgagattgta gaggaagaat
     3541 ctatctgtct gataggtcat tctattggag gcgatttagc tcgttatttc gcatcggaat
     3601 ttgaagaagt aaagaaactg attcttttgg atggtggcta tctagattta gataagattt
     3661 tacctttgga tacagagtta gaggaaacta aaaattatat caaatctcaa attatttcgg
     3721 acttagatgt tcttacttct aaagaaaaat ctgaagcaaa gcattggtca gaaaatatgg
     3781 agaaagctgt aagacagtcc tatcactgga atgttgagta taatagatat gagttggcta
     3841 taaattatga aaatatagaa gcgatactcc gcctacggag aaaaatacaa gcttttaaga
     3901 gagaagtggg agataccttg tttattagtc ctcgctatcc taatgaagct acatggagag
     3961 aggaagccct aaaagaattg ccagactatt ttgatactat ttttttagaa aactttggcc
     4021 atgagcttta tactcaagca cctaaagaaa tcgctagtct aatgaatgag tggctcgctt
     4081 attttctatg agctacttgt attgctggaa atggtataag atgaaaatct acaagtcact
     4141 aattttcata taacaaaaaa cgaacaggct ctttttctgt tattcagaag agaacttgtt
     4201 cgtttttatc ttgattttct taaaaagctc tatatacata gggattttct ggtttatcga
     4261 ctttggtaaa gctgtcgatt tccaaggttg gaaggttttg tttgagttct ttatggtagt
     4321 gattgaccag ttttcctttg gctgttatcc aagtgttgtt ttcatactgc cgggtattgc
     4381 ccttggtcag caatccatag acaccagaat ctgcgataca gtggataatg ccgaatcgga
     4441 acagaaattg actattggca tgactggggt cgttatagac aaagcctgta aactggattg
     4501 tcttgccctc aaactcatct ggatagtcgt agatagcctc catgacttcc atatagtttt
     4561 cattagtgat ctgaatacta tcttgggata agtatttatc cgccgccgtt cgcatttcct
     4621 tttcataggc tgattttgaa aaataagaac tggtatctgg tttcaaatat tggcttgtcg
     4681 tcccttcgct tgtctgaatg gctagatccg ttccttccga tagggggaaa tgataacctt
     4741 tagcagaaac agtctgagaa tccaagctaa cagttgggaa agttaagccg atgacaagtg
     4801 gaatagccag aagagaaata ctcgtcatct tggccaatcg gctgttcaga tgactgtggg
     4861 ttttgacttg cttcatccag atatacaatt gaacaattgc caagataaag gaaagcacca
     4921 tggaaatata ggccagatag gaatagtgca tgttgatgta ctggtttagt ttgcccgaca
     4981 gatggaggta aatagtcagt tcaaaatagc cagctaaaac taaaaatcga atcataggat
     5041 gactccaatc aagagagaat aggctaaaac gaccagagtc acaatcgtaa tgaagtgact
     5101 aataaatcgt gctttcaagt aatttttcat catgagaata tttttgatat ccagcattgg
     5161 gccaatgacg agaaaggcca gaactggagc caaaccgaaa ctcgagagta gagaagcacc
     5221 tataaaggca tccgcctcac tacagagcga aagaagaaag gccaaaagca tcaagagcag
     5281 gatggcaaaa agaggagtcg cactgataga ggtcagaatc cgagtcggaa cgtagacctg
     5341 tattatagaa gcaaagaggc agccaaatac caaataacgc cccgtatcaa aaaattcatc
     5401 aatggcctgc acaaagactt gaaaaacttt ttttgcagaa ctcaagtaag aaaaatcatg
     5461 ctcatgacaa gccagacgat tttctttctg aatcggttct tgccagaaaa atcctagaaa
     5521 aattcctagt attacagcca caagaatgga acccagagct cgtaataggg cgacatggaa
     5581 ggagttgcca aaggcagaat aggtcgcaaa aagaacaatg ggattgataa caggtgctgt
     5641 cacaagaaaa ggaactgccg tgtaacttgg aacctttttt tccagaaaac gattgatgat
     5701 ggggacgatt ccacattcac aagaagggaa aagtataccg acaaaggtcc caaaaaagat
     5761 tctcccccaa cgatttcgag ggagaaaatg ataaaccttg tcaggtgtga tataaacttc
     5821 aatcagccct gagacaatgc ttcctatcag aacgaaggga agggcttcaa tgataatgga
     5881 gagaaaaatg gctccagttt gaagtacact agatgggagt tgttgaaaag cagtcatcta
     5941 gtttttcttt tctgctttga cttttttctc tttgtcatca gggaaagtaa cttgtttcaa
     6001 atcagggagt ttagcaaact cttcaaacat cttgtccaag tcgtctcgtt ttgtaaattt
     6061 gacagccata ggtgtacctc gattctaaat tctacctcta ttatactatt attttgcgga
     6121 aaagggagtt ttttaatttg ttttcgatag ttgatacact tcgaaaatct cttcaaacca
     6181 cgtcagcttc gccttaccgt agtacggtta ctgacttcgt cagttctatc cacaacctca
     6241 aaacagtgtt ttgagctgac ttcgtcagtc ttatccacaa cctcaaaaca gtattttgag
     6301 cagcctgcgg ctagcttcct agtttgcttt ttgattttca ttgagtatga aaaggattgg
     6361 agaaagcctt ccagcttgtg gtataataga tttatggata aaaaatatga aaaaatctct
     6421 caggatttgg gagtgacgtt aaagcaaatt gataccgttc taagtttgac agctgaaggg
     6481 gcgactattc cctttatcgc gcgttatcgc aaggacatga ctggtagtct ggatgaggtg
     6541 gcgattaagg ctattattga tttggataaa agtctgacaa atctcaatga ccgtaaggaa
     6601 gctgtcttag ctaagattca agaacaaggt aagttgacca aggaattgga agaagctatc
     6661 ttagttgccg aaaaattagc agacgttgaa gaactctatc ttccttataa ggaaaagcgt
     6721 cgtaccaagg caaccattgc ccgtgaagct ggactctttc ctcttgctcg tttgattttg
     6781 cagaatatag ttgacttaga gaaagaagct gaaaagttcg tctgtgaagg atttgcgact
     6841 ggcaaggaag ccttgactgg tgcagttgat attttggtcg aagccttatc ggaagatgtg
     6901 accttgcgtt ctatgactta tcaggaagtg ctgagacact ctaaactcac ttctcaagcc
     6961 aaggatgaaa gtcttgatga aaagcaggtt tttcagattt attatgattt ttcagagaca
     7021 gttggaacta tgcaaggcta tcgtaccttg gctctcaatc gtggggagaa acttggtgtc
     7081 ttgaagatcg gttttgaaca tgcgacggac cgtattcttg ccttctttgc tactcgtttc
     7141 aaggtgaaaa atgcttatat tgatgaagtt gttcagcaat ccgttaagaa aaaggtcttg
     7201 cctgctattg agcgtcgtat tcggacagaa ttaactgaga aagctgaaga gggagctatc
     7261 caactttttt ctgacaatct gcgcaatctc ctcttggttg ctccactgaa agggcgcgtg
     7321 gttcttgggt ttgacccagc ctttcgtaca ggtgccaagc tagctgtcgt ggatgcaaca
     7381 ggaaaaatgc tgacaactca ggttatttat cctgttaaac cagcatcagc tcgtcaaatc
     7441 gaagaagcca agaaagattt agcagattta attggtcaat acggtgtaga gattattgcc
     7501 attggaaatg gaacggccag tcgtgaaagt gaagcttttg tagcggaagt tctgaaagat
     7561 ttccctgaag tcagctatgt tatcgttaat gaaagtggtg cttctgtcta ttctgccagc
     7621 gaacttgctc gtcaggagtt tccagacttg accgttgaaa aacgctctgc catttctatc
     7681 gcccgtcgtt tgcaagatcc tcttgcggaa ttggtcaaaa tcgatcctaa gtcaattggt
     7741 gtcggtcaat accaacacga tgtcagtcag aagaaactat ctgagagtct ggactttgtt
     7801 gtcgatacag tggttaacca agttggtgtc aatgtcaata cagctagccc agctcttctt
     7861 tcacacgtag ctggactcaa taaaaccatt tctgaaaata tcgtcaaata ccgtgaggaa
     7921 gagggaaaaa tcacttcacg ctcccaaatc aagaaagttc ctcgtttggg ggccaaggct
     7981 tttgaacagg ctgctggttt cctccgtatc cctgaaagta gcaatatcct tgataataca
     8041 ggagttcacc cagaaaatta cgctgccgtt aaggaactct tcaaatgctt ggacattaag
     8101 gatctgaatg aagaggccca aagcaaactc aagtcgcttt cagtcaagga aatggcgcaa
     8161 gagttagacc ttggtccaga aactcttaaa gatatcattg cagatcttct caaaccaggt
     8221 cgagatttcc gtgatttctt tgatgctcca gttctccgtc aagatgtcct agatatcaag
     8281 gacttagtgg ttggacaaaa gctagaagga gtggtgcgta acgttgttga tttcggtgct
     8341 tttgttgata tcggaattca tgaggacggt ctcatccata tttcccatat gagtcgcaag
     8401 tttatcaaac accctagtca agtggtggca gttggagatt tggtgagcgt ttgggttaag
     8461 aaaattgata ctgaacgtga aaaagttaat ctgtctctcc tagctccaaa tgaaactgac
     8521 tgattacgtc aagcaggttt tactagaaga cttcggcaga ccttttatcc atcatgtcca
     8581 gtggaatagg cgtctacgtt cgacaggtgg gcgatttttc cccaaagatg ggcatttgga
     8641 ttttaatccc aaggtttatc aggaactggg gttggacgtt tttaggaaaa ttgtccgaca
     8701 tgaactctgt cattatcacc tctattttca agggaaaggc tatcaacata aggatcggga
     8761 ttttaaggaa ctgttgaaag cagtggatgg attacggttt gtaccatcct tgcccaatag
     8821 taactccaag ccaatcaagc tctatcgttg ccaatcctgc cagcaaactt atcagcgtaa
     8881 gcgaagaatt gataccagac gctatcgctg tggactttgt cgaggtaaat tgctactaat
     8941 aaatcagcct gaggactgat gaaagccgag cctacccgtg atatactatg tctaacctag
     9001 cagaaagagg aaatatcatg aacagtaagt tttataaaat gagacgaaat tgcatgattt
     9061 caggagtttt agcaggtctg tcagacaagt ggaactttga tgttaccctt gtacgttttc
     9121 tgtttgccat ttttacagtc gcaaactttg gacttggggt gattatctat atcatcctag
     9181 cttctatcat gccaaccaag gaagaaatcg aagcagaaat gtacggaaca ggcccacgta
     9241 aacgcaaaga agctcaagcc attgacgata atgaaggctg gttttggtga ggttttacaa
     9301 aagatttgga atacgcaaaa agctttaaat caatagtcta aactgcttga tttaaagctt
     9361 ttttactttt atactcaata aaaatcaaag tgcaaactag gaagccagcc gcaggctgta
     9421 atttagtcgg caatgtgaag ttgacatagt ttgcactttg atttttgaat agtattaata
     9481 atatttcgtc agcttcatcc acaaactata gtggattgga actagaatag tacacctcta
     9541 cttctaaaac attgttagaa atcgatttga ctgtcctgat cgatttgtcc tgttcttatt
     9601 tcattttact ataaaagcag taatttaaat gcagtttttt aatctatttt tgctgctgag
     9661 acaatacatt tttggaaaaa tggtggatgc tgataacaac tgataaccag caaataacat
     9721 aagcagtgcc ggtaaattct gtaccgataa agtgtgtgtg ttcaactaag agctgaccga
     9781 tgaatggaga gagcagatag agaaatccga tgagtatatg ttctttgtgt ttcattaaaa
     9841 cgcaccttct ttccttatag gttgaacgac ttgcaagtgt taaattgaat ggtatgttat
     9901 ctaggtaacc ttactaaaat gttagttccc gcttcctcct ttttaaagta agccttttca
     9961 tacttatatt ttacaacttt aaaaatagga aatcaaatca ttttctaagt aattttgctt
    10021 atatttcacc caatcttaca aaaatgtaag attaaagtct cttttgtaag gttaggttat
    10081 ggcaagcggt ctttttttga tgtaaactag actcataaag aacaaaggag taacatcatg
    10141 aaacaaatct tacataagaa aactagaaaa ccaagtcaca aagaaattga gcgcattcag
    10201 ctgggatgca ctatgatgca agctacattt catttgatgg gatattaaga aaggagattc
    10261 tcatgacact tttagatgta aaacacgttc aaaaaattta taaaactcgt tttcagggca
    10321 accaagtaga ggccctcaag gatattcact tcaccgtaga aaagggtgac tacgttgcta
    10381 tcatgggtga gtctggttct ggtaaatcca ctctgctcaa tatcctagct atgctggata
    10441 aaccaagtcg tgggcaggtt tacctaaacg gaactgatac agcaactatt aaaaattcac
    10501 aggcttctag tttccggcgt gaaaagctag gatttgtctt ccaagacttt aacttgctag
    10561 atactctgtc tgttaaggac aatatcttgc ttccgcttgt cttgtcaaga agacctataa
    10621 cggagatgat gaagaaattg gtgatgacag ctgaaaatct gggtatcaac caattgcaag
    10681 agaagtaccc ttacgagatt tctggtggtc agaaacagcg tgtagcagta gcccgcgcca
    10741 tcatcacaga acctgaaatt ctccttgcgg acgagccaac aggagccctt gattccaagt
    10801 catctgcagc cttacttgat gtctttaatg aaatcaatga gcgtgggcaa accatcctca
    10861 tggtaaccca ctcaacagca gctgctagca gggccaagcg tgttctcttt atcaaagacg
    10921 gcattcttta caaccaaatc taccgtggag agaagacaga gcgtcagatg ttccaagaaa
    10981 tctctgatac cttgactgtc atggcaagcg aggtgaatta gtatgtttcg attaaccaat
    11041 aagttagcgg tatcgaactt gattaaaaac cgcaaactct actatccttt tgcgctggct
    11101 gttctcttgg cagtcactgt cacctatctc ttttactctc taaccttcaa tcctaagatt
    11161 gcggaaatcc gtggaggaac aaccattcag gctacacttg gatttggtat gtttgtcgtc
    11221 acccttgcgt cagccattat cgttctctat gccaatagtt ttgtcatgaa gaaccgttcc
    11281 aaggaactag gaatttatgg catgttgggc ttggagaagc gtcatcttat cagtatgacc
    11341 tttaaggagt tagtggtatt tgggattcta actgttggag cgggtatcgg tattggagcc
    11401 ttgtttgaca agttaatttt cgctttcctg ctcaaactaa tgaaattgaa ggttgagctg
    11461 gttgctacct tccagacgaa agttgtcatt acagtgcttg ttgtcttcgg tttgattttc
    11521 ctaggcctca tgttcctgaa tgcccttcga atcgcccgta tgaatgccct ccagctctct
    11581 cgtgagaaag ctagtggaga gaaaaaaggt cgcttccttc ctctccaaac cattcttggt
    11641 tccataagtt taggaattgg ctattatctt gcccttacgg taaaagatcc tcttacagcc
    11701 ttaacaacct tcttcatagc tgttttactg gttatctttg ggacttatct cttgtttaat
    11761 gcagggatta ccgttttcct ccaaatctta aagaaaaata agaaatacta ttaccaacca
    11821 aataacctca tatctgtttc taacttgatt ttccgtatga agaaaaatgc agttggacta
    11881 gccaccatcg ctatcttgtc aacaatggtt ttggtaacca tgtcagcagc gacaagcatt
    11941 ttcaattcct cagaaagctt taaaaaagtt ctaaatcctc atgattttgg ggtttcaggg
    12001 caaaatgttg aaaaagaaga cttggacaaa ctcttgagcc agtttgcaag tgacaaaggt
    12061 tataagatta aagaaaaaga agtatttcgt tacacttact ttgctgttgc gaatcaagaa
    12121 ggaaccaagt taactatttt tgaaaaagga caaaaccgtg tccaaccaaa aacagttttc
    12181 atggtatttg accaaaaaga ttatgaaaat atgactggtc aaaaactgtc tctatcagga
    12241 aatgaggtcg gactctttgc aaagaatgag ggagttaaag aacagaaagc tctaactcta
    12301 aatgatcatc aattttctgt aaaagaagaa tttactaaag attttattgt caaccatgtt
    12361 ccaaatcagt ttaatatttt gactgctgat tacaattacc ttgttgtacc tgatttacaa
    12421 gcctttttgg atcaattccc agattcggct atctataatc agttttacgg tggtatgaat
    12481 gtaaatgcca gtgaagcaga acaactcaag gtcgctgagg agtatgaaaa atacttacaa
    12541 aagtttaatg ctcaattaaa cactgaaggt agctatgttt atggtagcaa tctagcagat
    12601 gctagtgctc agatgagtgc cctctttggt ggtgtcttct ttatcggtat tttcttatcc
    12661 attatcttta tggtcggaac cgttctggtc atctactaca aacaaatttc tgaaggatat
    12721 gaagaccgtg agcgctttat tatcttgcag aaagtcggtt tagatcaaaa gcaaatcaag
    12781 caaaccatca acaaacaggt tttaactgta ttcttccttc ctttgctctt tgccttccta
    12841 catctagcct ttgcctacca tatgcttagt ctgattttaa aagtgattgg tgtactggat
    12901 acgactatga tgttgattgt gaccttgtct atctgcgcta tcttcctcat cgcctatgtg
    12961 ctgattttca tgattacttc aagaagttat cgtaagattg tccaaatgta aaaaaagata
    13021 cctcgacttc aaaatcgagg tatttcttgt tttctaaatg ctgaaaagtt gtccgagcag
    13081 gaaggtaact cccatagtta agagaccaat agcaaggttc cgaatcatag ctgttttggt
    13141 tggggctttt ccaagtctag cacttgtgta gccagtgaga agaagggcta caccgacgat
    13201 aaggacggta gcagggatgc ggtaatcact tggaaaaatg gtcactgaca gcattggagg
    13261 caaacttcta aggaaaaagg caacgaagct agaaatggca gcgtgccaag gattggtaaa
    13321 ttcttcatac tcaatcccat atttttcctc taccagagcc ttgagtggat ttttaagaaa
    13381 gatcttatta gtcaagagtt gggcagaagt tttgaattct ccattttgga tataagaagc
    13441 atagagggat tttttggcta gttccctatc ttggtctagc aagagttttt ctcgcgaaac
    13501 ggcagcttcc tcggtatctt ttggagttga aacggataca tattctccac cagccattga
    13561 aaaggcacca gctaagatag ccgcaaaacc tgataaaaag ataatccaga tattgctcgt
    13621 ggcactggca actccgataa ccacaccagc aatggaaata attccatcgt tagcatcaag
    13681 aacacccgca cgcaggatat ttaaacgacc tgcaaaattt gaatcaattt cgtgatttgt
    13741 ttctgacgct aaatttcaag ttcaagttag ccatccagaa gtcttctctg ggtgacttgt
    13801 agtccaagca ttttttagga tagttgttaa tccacttttc gatgaatgcg acttctttgg
    13861 gagtcatttt cttggttccc ttaggtaacc atctacgaat gaacctgtta tgattctcat
    13921 tagttcccct ttcccaagag gcataggggt gcgcataata gatgtgctcc tcagaaaata
    13981 catcaaacaa gcgattgaat tccgttccat tatctgccgt gatggaaaga atcttgtgtt
    14041 gttttaagat gagttttaga gcctgattga ccacctcagc acttttattt ggaatcaatc
    14101 ggatgatctg atgtctactc tttcgatccg tcaagacaag caagcagtag tttttcgctc
    14161 tcgtaagtag aaccgtatca atctcataat acccattctc caagcgaaga ttgatagctt
    14221 cagaccgctg ttcgatggat tgaccagcag gtttaaagtt ggtgctagcc tgtttcttat
    14281 caggcgaaaa tttttggtta tgatagtgga gaatcttttc ctttagttcc ttggtcaagc
    14341 ttgatttctt gaccgagtgc ttgcgattat tttcataaga ctgttgagca tagtcggcag
    14401 aataaacctc tttgaagcgc ccttttccaa gacattttcg gactgtccta cgcttgattt
    14461 cagtgtggat agtttgagga gcttttccaa gtagagaggc aatttctcta tttgattttc
    14521 cttctttttt ccatctttcg attaagcgac ggctatcgat tgtcaaatgt ttggcttttg
    14581 tagtataatt gtcttgcatc tctgtgcctt tcttgtgttt gtggttgaac aacaagtata
    14641 acacagaggt gttttcttat gcctacaaga gctatcagct agttgaacca tctaattttt
    14701 aggagggctg ggtggctaac ttcattatag aactttcatt tacgaacata tagtaaaatg
    14761 aaacaagaac agaacaaatc gatcaggaca gtaaaatcta tttctaacaa tgttttagaa
    14821 gcagaggtgt actattctag tttcaatcta ttatattttt gttttttatc aaaaaatact
    14881 ttacaagttc ttaaaaacat gatatagtaa taaagcttag aaaatgagat gatgttttct
    14941 agcaaatata aacccgagta aaaaatgcct acggacaggc agggttgaat gccgaagcgt
    15001 ggttgaaaag ccacattatt gatagggtta aaagcctact tttataagtt gatgttagga
    15061 cacttgtcct aattcataaa tttttagtgt ggtgaaagca cacgtcatct tgtgaaacga
    15121 tcaataaagt acgtaatatt tgctactaga gagttaggaa acatcgggaa cagacatact
    15181 caacagaaac caaaataaac acgtcagaag attgcagagc aggtgaaaac ctgctctttt
    15241 ttcatgagtc aacctttagt tccttagttt tcataaggtc ctaaaaatat tgaaaggagt
    15301 atgttttgaa agagttagat caaaaccaag ccccaattta tgaggccttg gtgaagttac
    15361 gcaagaaaag gattgttccc tttgatgttc caggtcacaa gcgtggacgg ggaaatccag
    15421 aacttgtcga actcttagga gaaaaatgtg taggcattga tgtcaattcg atgaaaccct
    15481 tggataattt aggccatcct atttcgatta ttcgtgatgc agaggagctg gctgcagatg
    15541 cttttggagc tagccatgcc tttctaatga ttggtggaac aacttcatcg gtgcagacta
    15601 tgattctggc aacctgcaag gcaggagata agattattct gccacgaaat gtccataaat
    15661 ctgctatcaa tgcgttggtt ctatgtggtg ccattcccat ctatatcgag atgagtgtag
    15721 atcctaagat tggtatcgct ttaggtcttg aaaatgaccg agtagcacag gccataaagg
    15781 accatccaga tgctaaggct atcctaatca acaatcctac ttactacggc atatgttcag
    15841 acctaaaggg gttgacagaa atggctcatg aagctggcat gatggtttta gtagatgaag
    15901 cccatggagc gcatttgcat ttcactggta aacttccaat ttctgctatg gatgcaggag
    15961 ctgatatggc agcagtttcc atgcataagt ctggtgggag tttgacacaa agttcgcttc
    16021 ttttaatcgg ggagcagatg aatcccgagt acgttcgtca gattataaac ctgacacagt
    16081 ctacatctgc ctcttactta ttgatggcta gtttggatat ttcacgtcgc aacttggccc
    16141 ttcgtggtaa agagtcgttt gaggaagtca ttgagctatc cgagtacgct cgtcatgaaa
    16201 tcaatgccat tggcggttac tatgcttact caaaagagtt aatagatggt gtgtcggtct
    16261 gtgattttga tgtaaccaag ttgtcagttt acactcaggg aataggctta acaggtatcg
    16321 aggtttatga cctcttgcga gacgaatacg acattcagat cgagtttggt gatatcggca
    16381 atatcttggc ctatatttcc atcggcgacc gcatccaaga catcgagcgc ttggttggtg
    16441 ctctggctga tattaagaga ctctattcac gagatgggaa ggacttaata gctggagaat
    16501 atattcagcc cgagttggtg ctgtctccac aagaagcctt ctattcagag agaaaaagtt
    16561 tgaccttaga tgagtctgtt ggacaggtct gtggagaatt tgtcatgtgc tatcctccag
    16621 ggattcctat cttggctcct ggtgaacgca ttacacgaga aattgtagac tatatccaat
    16681 tcgccaagga acgtggttgc tccctccaag ggacggaaga tccagaggtc aatcatatca
    16741 acgttattaa gagaaagaca aactataaga aaagtcaata gttttatcta aactatttct
    16801 tatttcaatt tgatgatttg gcgatgattt tagagcacgg caaaaagccc ttgaattaga
    16861 agcggtcaat cgcttaattt ctatcagctt atcaaatcct gcctcaatcc ttttctgagg
    16921 attagggtag cgtgtcaaga gttggtaggt at
//
LOCUS       DBEJAU010000046        16939 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC323 isolate 683620
            SAMN38261939-rid24807223.denovo.046, whole genome shotgun sequence.
ACCESSION   DBEJAU010000046 DBEJAU010000000
VERSION     DBEJAU010000046.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261939
            Sequence Read Archive: SRR26833919
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 16939)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16939)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576303.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576303.1
            Genome Coverage       :: 154x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/19/2025 01:05:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,121
            CDSs (total)                      :: 2,078
            Genes (coding)                    :: 1,943
            CDSs (with protein)               :: 1,943
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 36
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 72 of 135
            Pseudo Genes (incomplete)         :: 63 of 135
            Pseudo Genes (internal stop)      :: 51 of 135
            Pseudo Genes (multiple problems)  :: 46 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16939
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261939-rid24807223.denovo.046"
                     /strain="GPSC323"
                     /isolate="683620"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            complement(272..1907)
                     /locus_tag="ACL29Z_001649"
                     /pseudo
     CDS             complement(272..1907)
                     /locus_tag="ACL29Z_001649"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001237556.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(1888..2637)
                     /locus_tag="ACL29Z_001650"
     CDS             complement(1888..2637)
                     /locus_tag="ACL29Z_001650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000569185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGR0069926.1"
                     /translation="MIEFQNVSKLYGDKEALSNLNLQIENGEIMGLIGHNGAGKSTTI
                     KSLVSIISPSSGRILVDGQELSENRLAIKRKIGYVADSPDLFLRLTANEFWELIASSY
                     DLTSSDLETSLARLLNVFDFAENRYQVIETLSHGMRQKVFVIGALLSAPDIWVLDEPL
                     TGLDPQAAFDLKQMMKEHAQKGKTVLFSTHVLEVAEQVCDRIAILKKGHLIYCGSVEN
                     LRKDHPDQSLESIYLSLAGRKEEVSDASQGH"
     gene            2816..4270
                     /locus_tag="ACL29Z_001651"
     CDS             2816..4270
                     /locus_tag="ACL29Z_001651"
                     /EC_number="3.2.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001181079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004556 - alpha-amylase activity [Evidence
                     IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-amylase"
                     /protein_id="HGR0069927.1"
                     /translation="MQNQTLMQYFEWYLPHDGQHWTRLAENAPHLAHLGISHVWMPPA
                     FKATNEKDVGYGVYDLFDLGEFNQKGTVRTKYGFKEDYLQAIQALKTQGIQPMADVVL
                     NHKAAADHREAFQVIEVDPVDRTVELGEPFTINGWTSFTFDGRQDTYNDFHWHWYHFT
                     GTDYDAKRRKSGIYLIQGDNKGWANEELVDNENGNYDYLMYADLDFKHPEVIQNIYNW
                     ADWFMETTGVAGFRLDAVKHIDSFFMRNFIRDMKEKYGDDFYVFGEFWNPDKEANLDY
                     LEKTEEHFDLVDVRLHQNLFEASQAGANYDLRGIFTDSLVELKPDKAVTFVDNHDTQR
                     GQALESTVEEWFKPAAYALILLRQDGLPCVFYGDYYGISGQYAQEDFKEILDRLLAIR
                     KDLAYGEQNDYFDHANCIGWVRSGAENQSPIAVLISNDQENSKSMFVGQEWTNQTFVD
                     LLGNHQGQVTIDEEGYGQFPVSARSVSVWAVNTI"
     gene            complement(4360..6978)
                     /gene="alaS"
                     /locus_tag="ACL29Z_001652"
     CDS             complement(4360..6978)
                     /gene="alaS"
                     /locus_tag="ACL29Z_001652"
                     /EC_number="6.1.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012130635.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004813 - alanine-tRNA ligase activity
                     [Evidence IEA];
                     GO_process: GO:0006419 - alanyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alanine--tRNA ligase"
                     /protein_id="HGR0069928.1"
                     /translation="MKQLSSAQVRQMWLDFWATKGHSVEPSVSLVPVNDPTLLWINSG
                     VATLKKYFDGTIIPENPRITNAQKAIRTNDIENVGKTARHHTMFEMLGNFSIGDYFRD
                     EAITWAYELLTSPEWFDFPAEKLYMTYYPDDKDSYNRWIEVGVDPSHLIPIEDNFWEI
                     GAGPSGPDTEIFFDRGEAFDPENIGLRLLAEDIENDRYIEIWNIVLSQFNADPAVPRS
                     EYKELPHKNIDTGAGLERLVAVIQGAKTNFETDLFMPIIREVEKLSGKVYDQDGDNMS
                     FKVIADHIRSLSFAIGDGALPGNEGRGYVLRRLLRRASMHGQKLGINEPFLYKLVPTV
                     GKIMESYYPEVLEKRDFIEKIVKSEEESFARTLHSGQHFAQGIVADLKEKGQSVIAGQ
                     DVFKLYDTYGFPVELTEEIAEEAGMTVDREGFEAAMKEQQERARASAVKGGSMGMQNE
                     TLQNITVESVFNYNTSQLSSKLVAIVADNAEVGAVSEGTASLIFAETSFYAEMGGQVA
                     DYGQILDESGKIVATVTNVQKAPNGQALHTVEVLAPLALNQEYTLAIDSNRRHRVMKN
                     HTATHLLHAALHNILGNHATQAGSLNEVEFLRFDFTHFQAVTAEELRAIEQQVNEKIW
                     EALEVKTVETDIDTAKEMGAMALFGEKYGKEVRVVTIGDYSIELCGGTHVGNTSEIGL
                     FKIVKEEGIGSGTRRILAVTGKEAFEAYREQEDALKAVAATLKAPQVKEVPHKVEGLQ
                     EQLRQLQKENAELKEKAAAAAAGDIFKDAKEVNGRRYIASQVSVSDAGALRTFADNWK
                     QKDYSDLLVLVAAIGDKVNVLVASKTKDLHAGNLVKELAPIIDGRGGGKPDMAMAGGS
                     NQAKIQELLDAVAGKL"
     gene            complement(7000..7485)
                     /locus_tag="ACL29Z_001653"
     CDS             complement(7000..7485)
                     /locus_tag="ACL29Z_001653"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000847073.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LURP-one-related/scramblase family protein"
                     /protein_id="HGR0069929.1"
                     /translation="MKTFLVKQKFRLGGERFAIKDDRGEIAYQVEGSFFKIPKTFTIY
                     DAAGEQVSQISKEILTLLPRFEIQLRDGSSFVIRKKLTFWRDKYEFDNLGLRIEGNIW
                     DLNFKLLDDRDQLIAEIKKELFHLTSTYTVTVLEDAYADLVISLCVAIDYVEMLESQS
                     H"
     gene            complement(7760..7999)
                     /locus_tag="ACL29Z_001654"
     CDS             complement(7760..7999)
                     /locus_tag="ACL29Z_001654"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000784186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0069930.1"
                     /translation="MKMSTFFKKSFWPTFMIVNQTAILFHLNDGLDRQYLTTESIYWV
                     IGTFIFGNILVAVFSNMKIWDKKKNGSKKKYILKK"
     gene            complement(8260..9330)
                     /locus_tag="ACL29Z_001655"
     CDS             complement(8260..9330)
                     /locus_tag="ACL29Z_001655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000725675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HGR0069931.1"
                     /translation="MKKIYSFLAGIAAIILVLWGIATHLDSKINSRDSQKLVIYNWGD
                     YIDPELLTQFTEETGIQVQYEAFDSNEAMYTKIKQGGTTYDIAIPSEYMINKMKDEDL
                     LVPLDYSKIEGIENIGPEFLNQSFDPGNKFSIPYFWGTLGIVYNETMVDEAPEHWDDL
                     WKLEYKNSIMLFDGAREVLGLGLNSLGYSLNSKDPQQLEETVDKLYKLTPNIKAIVAD
                     EMKGYMIQNNVAIGVTFSGEASQMLEKNENLRYVVPTEASNLWFDNMVIPKTVKNQDS
                     AYAFINFMLKPENALQNAEYVGYSTPNLPAKELLPEETKEDKAFYPDVETMKHLEVYE
                     KFDHKWTGKYSDLFLQFKMYRK"
     gene            complement(9327..10100)
                     /locus_tag="ACL29Z_001656"
     CDS             complement(9327..10100)
                     /locus_tag="ACL29Z_001656"
                     /EC_number="7.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398754.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HGR0069932.1"
                     /translation="MKKFANLYLGLVFLVLYLPIFYLIGYAFNAGDDMNSFTGFSWTH
                     FETMFGDGRLMLILAQTFFLAFLSALIATIIGTFGAIYIYQSRKKYQEAFLSLNNILM
                     VAPDVMIGASFLILFTQLKFSLGFLTVLSSHVAFSIPIVVLMVLPRLKEMNGDMIHAA
                     YDLGASQFQMFKEIMLPYLTPSIIAGYFMAFTYSLDDFAVTFFVTGNGFSTLSVEIYS
                     RARKGISLEINALSALVFLFSIILVVGYYFISREKEEQA"
     gene            complement(10097..10903)
                     /locus_tag="ACL29Z_001657"
     CDS             complement(10097..10903)
                     /locus_tag="ACL29Z_001657"
                     /EC_number="7.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398755.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HGR0069933.1"
                     /translation="MKKTSSKLFVVPYMLWIALFVLAPLVLIFGQSFFNIEGQFSLEN
                     YKSYFASQNLTYLKMSFNSVLYAGIVTFVTLLISYPTALFLTRLKHRQLWLMLIILPT
                     WINLLLKAYAFIGIFGQNGSINQFLEFIGIGSQQLLFTDFSFIFVASYIELPFMILPI
                     FNVLDDMDNNLINASYDLGATKWETFRHVIFLLSMNGVRSGVQSVFIPSLSLFMLTRL
                     IGGNRVITLGTAIEQNFLTNDNYGMGSTIGVILILTMFITMWVTKERRER"
     gene            complement(10884..12041)
                     /locus_tag="ACL29Z_001658"
     CDS             complement(10884..12041)
                     /locus_tag="ACL29Z_001658"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018372333.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGR0069934.1"
                     /translation="MKKPIIEFKNVSKVFEDSNTKVLKDINFELEEGKFYTLLGASGS
                     GKSTILNIIAGLLDATTGDIMLDGVRINDIPTNKRDVHTVFQSYALFPHMNVFENVAF
                     PLRLRKIDKKEIEQRVAEVLKMVQLEGYEKRSIRKLSGGQRQRVAIARAIINQPRVVL
                     LDEPLSALDLKLRTDMQYELRELQQRLGITFVFVTHDQEEALAMSDWIFVMNDGEIVQ
                     SGTPVDIYDEPINHFVATFIGESNILPGTMIEDYLVEFNGKRFEAVDGGMKPNEPVEV
                     VIRPEDLRITLPEEGKLQVKVDTQLFRGVHYEIIAYDELGNEWMIHSTRKAIVGEEIG
                     LDFEPEDIHIMRLNETEEEFDARIEEYVEIEEQEAGLINAIEEERDEENKL"
     gene            complement(12100..13050)
                     /gene="murB"
                     /locus_tag="ACL29Z_001659"
     CDS             complement(12100..13050)
                     /gene="murB"
                     /locus_tag="ACL29Z_001659"
                     /EC_number="1.3.1.98"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000116191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008762 - UDP-N-acetylmuramate
                     dehydrogenase activity [Evidence IEA];
                     GO_function: GO:0071949 - FAD binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramate dehydrogenase"
                     /protein_id="HGR0069935.1"
                     /translation="MSVREKMLEILEGIDIRFKEPLHSYSYTKVGGEADYLVFPRNRF
                     ELARVVKFANQENIPWMVLGNASNIIVRDGGIRGFVILCDKLNNVSVDGYTIEAEAGA
                     NLIETTRIALRHSLTGFEFACGIPGSVGGAVFMNAGAYGGEIAHILQSCKVLTKDGEI
                     ETLSAKDLAFGYRHSAIQESGAVVLSVKFALAPGTHQVIKQEMDRLTHLRELKQPLEY
                     PSCGSVFKRPVGHFAGQLISEAGLKGYRIGGVEVSEKHAGFMINVADGTAKDYEDLIQ
                     SVIEKVKEHSGITLEREVRILGESLSVAKMYAGGFTPCKR"
     gene            complement(13162..13914)
                     /locus_tag="ACL29Z_001660"
     CDS             complement(13162..13914)
                     /locus_tag="ACL29Z_001660"
                     /EC_number="3.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000152219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0070007 - glutamic-type endopeptidase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YhfC family glutamic-type intramembrane
                     protease"
                     /protein_id="HGR0069936.1"
                     /translation="MTIHIIITMLLLLAFLIGSIWFAKKKYQINLAVLGLGAVAFFVS
                     SQILEKLVHILILHPQKDGSIALLQDHPLIYIIYGLAMAAFFEETARLVFFKWLEKKR
                     SLEKADALAYGLGHGGLELIFLGLISLLNLYIVLSAVQTQNPQVMQLLSENMLKTIQS
                     LSVWQIYLLGFERILALGFQLLLTVWVYQAVRQKKWIYLLAAYGLHAFFDLAPSLFQV
                     GWLTNPVLVEVILALELVLVAYGTKEIFCKKS"
     gene            complement(13924..14655)
                     /gene="budA"
                     /locus_tag="ACL29Z_001661"
     CDS             complement(13924..14655)
                     /gene="budA"
                     /locus_tag="ACL29Z_001661"
                     /EC_number="4.1.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000360290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0047605 - acetolactate decarboxylase
                     activity [Evidence IEA];
                     GO_process: GO:0045151 - acetoin biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acetolactate decarboxylase"
                     /protein_id="HGR0069937.1"
                     /translation="MDKNVQEPVKLFQYNTLGALMAGLYGGTMTVGELLEHGDLGLGT
                     LDSIDGELIVLDGKAYQAKGSGDQPEIVEVSPDALIPYAAVVPHQAEVIFRQRFEMTD
                     KELKERIESYYDGENLFRSIKIRGEFSHMHVRMIPKSTPDTKFADVATHQPEYSRDNV
                     AGTIVGFWTPEIFHGVSVAGYHLHFISDDLTFGGHVMDFVIKEGIIEVGAVDQLDQRF
                     PVQDRQYLFAKFNVDEMKKDIEKAE"
     gene            14797..16068
                     /locus_tag="ACL29Z_001662"
     CDS             14797..16068
                     /locus_tag="ACL29Z_001662"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PLP-dependent aminotransferase family protein"
                     /protein_id="HGR0069938.1"
                     /translation="MKKQSKYKEVVSYLKNGIESERFPTGSRLPSIRQLSLDFHCSKD
                     TIQRALLELRHEQYLYAKPQSGYYVLEQGQHQDLEIEVTDEHASAYDDFRLCVNETLI
                     GRENYLFNYYDNQEGLEDLRQSIHKLLFEQALYCKANQLVLTSGTQQALFILSQISFP
                     RQAKEILVEQPTYHRMNRLLIAQGLDYQTIERGIDGIDLEELEGHFKTGKIKFFYTIP
                     RFHYPLGHSYSEQDKRSILNLAAKYDVYIVEDDYLGDLDSKKGQTFHYLDTEEHVIYI
                     KSFSTSLFPALRITALILPNAIKEAFVAYKNILDYDSNLIMQKALSLYIDSQLFEKNR
                     LARLTNHESYQKQIEERITKTPCPLPHYPLHDGLLLDLRQYPKIASLKHSQLGLDFFE
                     EAYLSTCPYQFAKVSLDNLENVLNYLKAELE"
     gene            complement(16088..16903)
                     /locus_tag="ACL29Z_001663"
     CDS             complement(16088..16903)
                     /locus_tag="ACL29Z_001663"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000837371.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HGR0069939.1"
                     /translation="MKSKKWIFVLCNFLASFFLVACQSGSNGSQSAVDAIKQKGKLVV
                     ATSPDYAPFEFQSLVDGKNQVVGADIDMAQAIADELGVKLEISSMSFDNVLTSLQTGK
                     ADLAVAGISATDERKEVFDFSIPYYENKISFLVRKADVEKYKDLTSLESANIAAQKGT
                     VPESMVKEQLPKVQLTSLTNMGEAVNELQTGKIDAVHMDEPVALSYAAKNAGLAVATV
                     SLKMKDGDANAVALRKNSDDLKEVVDKVIQKLKDEGTYQSYLEKAASLTEVEE"
BASE COUNT         5118 a         3811 c         3322 g         4688 t
ORIGIN      
        1 cacctatttg catcattcta tttcgaactc taaatatatg ttctatcaaa aatacttgaa
       61 aaagacacat tataggaatt aacgtttttg aaattgaaaa atatcccaat aaataaacta
      121 taaacaacaa taatagaact atattatatt tcttattcaa aacattcctc cctatatttt
      181 tgattaccaa tcttaatcat ttacaactac attctaacaa actataaaag cgtttgtcga
      241 attgaattta tcaagcaagc aaccaactat ctcatctttt ttctatttct gccaatatgc
      301 gtgacaggta ataatgatag ccaaaaatag caagagcaag caagacgata agagctccta
      361 ctcccaagtt gatggcaagg ataggggaga gagactgaac caagaatatg ctcccaatta
      421 caagggccat caggattgca ctataaataa acaataaaac tatggcgact atgccatttg
      481 aacgattcac caggtccgta atgctactcc aattggttga cagattttta acgtccttaa
      541 agtaatggtg gcaagaaagg atgacactgg caatgatcca gactacaaga aggtaaatca
      601 tcgaaaggat ggacaagcct agatatagag aaagaccgag caaagtcaga actggtaaaa
      661 aggactgaac agcaaagata atccaaaatt tcactttcac ataacgagca aagtcaaagg
      721 gtaaactctt cagaaaatca acattttccc tctccaagga caaggcaatt gaatgcaggc
      781 tggtgatatt gttattgaca actgctataa acactcctac aaaaaacaag ggtaaccagt
      841 atggaggatg aatgtctgga actatctgag aatctcggat tttggaaatc agactgatca
      901 tcatgagata aggaaggaaa gcacttgtaa aaagcactgt aatcacacca gtcccctgtc
      961 ccaagagggt gaggtggtag cgtaaaacca tacggaaaaa gcccttttta gtagttgaaa
     1021 tcctctcctt gctgcgacgt tcttttttga ccttctcctc actgttaagc aggatcacgt
     1081 cataaaaacg aggaaggacc ttctttttgg tcagataaag caggaagaga gttagtccta
     1141 tccaagcgag cagacccact aaggcttctg tcgaaaaagg ctccactgct attttgtaaa
     1201 agatatgaag aggataaagg agaaatggaa tgtctctaac tttgtcaaca atacttccaa
     1261 aagtcgactg aagaaagaag ataaatatta aaggtatgag aactcctatc ccaatcatca
     1321 cattcgaaaa aatagactga tactttctga agaccctagt ctgagccaag aaatgtactg
     1381 ccactaccat cactaaagta acagagacaa ataataaggt caaggacagt agcatcaaag
     1441 gcaaacccaa ccacagagaa ggtgctagcc taatgtagag gaccagaaaa taagctagga
     1501 ttggtacaat tccagctaga gctggcaaga ggacagacag acctttggcc attataatct
     1561 ctgattcttt aaaggcatag ggcctatagg aggccaggtc cttactctca taaaagacat
     1621 tgtaaaatgc agtgaaagaa gttgaaaagg ccagcaccag taaaatagca accatcgtac
     1681 taaaaaaaac ttggcatttc ctcaaaagga aaacgaaagg ctatatttat aaacatgaaa
     1741 agcatcaaga gactggaaaa aatgtaagaa cttaggactc tagcggaaac atttactttt
     1801 tttccagtat ttttagcttg cttctttcgt aggttagcca gattagcttc ttgagatgaa
     1861 tagaggatat tgatatcaac taatttttta atgaccttga gacgcatctg aaacctcctc
     1921 ttttctacca gcaaggctaa ggtagatact ttccaaagac tggtctgggt ggtctttcct
     1981 caagttctct acactaccac aatagatcaa atgccccttt ttcaaaatag caatccgatc
     2041 acagacttgc tcggctacct ctaggacatg agttgaaaac aagaccgtct tgcctttttg
     2101 tgcatgttcc ttcatcattt gcttcaaatc aaaggcggcc tggggatcca aaccagtcaa
     2161 gggttcgtcc aaaacccaaa tatcaggagc agacaagagt gccccaatga caaagacttt
     2221 ctgacgcatt ccgtgagaaa gagtttcaat aacctgatag cggttttcag caaaatcaaa
     2281 aacgttcaat agcctagcta gactagtctc caagtcagag ctagtcagat cataggatga
     2341 agcgatcaat tcccaaaatt cattggccgt taagcgtaaa aataagtcag gcgagtctgc
     2401 tacgtagcca atctttcgtt tgatcgccaa gcgattttcc gataactcct gaccgtctac
     2461 caaaatacga ccactgctgg gtgaaatgat actgactagg gattttatgg tggtcgattt
     2521 tccagcccca ttatgaccaa tcaagcccat aatctctcca ttttcaatct gcaaattgag
     2581 attactcaag gcctctttat caccatacaa cttactaaca ttttgaaatt caatcatggg
     2641 acaactccta tctttatctg tattatacat cgctatacta gcactttgat acaaaaaaat
     2701 caatacttta ttttaagtag ttaaaatagt ttccttctat cttacgcaaa cgtttgcgct
     2761 aatagatgct ttatgataga ataaagaaca agattgacaa gtaagaggaa acatcatgca
     2821 aaatcaaaca ctcatgcaat actttgaatg gtatctgccc cacgacggtc aacactggac
     2881 gcgtctggct gaaaatgctc cacacctagc tcatctgggg atcagtcacg tctggatgcc
     2941 accagccttc aaggcaacca acgaaaaaga tgtcggctat ggggtctatg acttatttga
     3001 cttaggagag ttcaaccaaa aagggactgt ccgcaccaag tatggtttca aagaagacta
     3061 tcttcaagcc attcaagccc ttaaaacaca gggaattcaa cctatggccg atgtagttct
     3121 caaccacaag gctgctgctg atcacaggga agcctttcag gttattgaag tggatcctgt
     3181 agaccgtaca gttgaacttg gagaaccctt caccatcaat ggctggacta gttttacctt
     3241 cgatggtcgc caagatacct acaatgactt ccactggcac tggtaccact tcacaggtac
     3301 agactatgat gccaaacgcc gtaagtctgg gatttatctg atccaagggg acaacaaggg
     3361 ctgggctaac gaggaattgg tcgataacga aaacggaaac tacgactacc tcatgtatgc
     3421 cgacctagac tttaaacatc ctgaagtcat ccaaaacatc tataactggg ctgattggtt
     3481 catggaaacg actggtgtag ctggtttccg tttggatgcc gttaagcata ttgactcttt
     3541 ctttatgcgc aacttcatcc gcgatatgaa ggaaaaatat ggtgacgatt tctatgtttt
     3601 tggtgaattt tggaacccag acaaggaagc caatctggac tatctcgaaa aaacggaaga
     3661 acactttgac cttgtcgatg ttcgtctcca ccagaatctc tttgaagcca gtcaagctgg
     3721 cgcaaactat gaccttcgtg gcattttcac agatagcctg gttgaactca agcctgacaa
     3781 ggctgtgact tttgtcgaca accacgatac ccaacgagga caagcccttg agtctaccgt
     3841 tgaagaatgg ttcaagccag cagcctatgc cctcattttg ttacgccaag acggccttcc
     3901 atgtgtcttt tacggagact actatgggat ttcaggccag tatgctcaag aagatttcaa
     3961 agaaatcctt gaccgcctcc tagccatccg aaaagacttg gcctatggag aacaaaatga
     4021 ctactttgac catgctaact gtatcggttg ggtacgttca ggtgctgaaa atcaatcccc
     4081 aatcgcagtc cttatctcaa atgaccaaga aaacagcaag tcaatgtttg tcggtcaaga
     4141 atggactaat caaacctttg tagatttact tggtaaccac caaggtcaag ttacaattga
     4201 tgaggaaggt tatggacaat tccctgtctc agctagatcc gtaagtgtct gggcagtcaa
     4261 taccatctaa tagctcataa taaccaagct aggtccaagc ggatttggct tttttgtatt
     4321 cacaaaaaga cctacccaaa tggatagatc tttacttgat tacaatttac ctgctactgc
     4381 atccaacaat tcttggatct tagcttggtt gcttcctcct gccatggcca tgtctggttt
     4441 accaccacca cgtccatcga tgattggtgc taattctttg acaaggtttc ctgcatgaag
     4501 gtcttttgtc ttgcttgcta caaggacatt gactttgtca ccgatagcgg caactaggac
     4561 aagaagatca gagtagtctt tttgtttcca gttatctgca aaagtacgaa gggcaccggc
     4621 atcggataca gacacttgac tagcaatgta acgacgaccg ttgacttcct tagcatcttt
     4681 gaagatatcg cctgcggctg cagctgcggc tttttctttc aactcagcat tttctttttg
     4741 aagttgacga agttgttctt gaagtccttc taccttgtga ggtacttcct tgacttgagg
     4801 tgctttcaag gttgctgcga cagctttaag agcatcctct tgttcacgat aggcttcaaa
     4861 ggcttcctta ccagtcactg ccaagatacg gcgagttcct gaaccgattc cttcttcttt
     4921 gacaattttg aagagaccaa tctcagaagt gttgccaaca tgagtaccac cacaaagttc
     4981 aatagagtag tcaccgatag tcacgacacg aacttccttg ccgtatttct caccaaagag
     5041 ggccatagct cccatttctt tagcagtgtc aatatccgtt tcaactgtct tcacttcaag
     5101 tgcttcccaa attttctcgt taacttgctg ttcaatcgca cgaagttcct cagcagttac
     5161 tgcttggaag tgggtaaagt caaagcgaag gaattcaact tcgttaagag atcctgcctg
     5221 tgttgcgtgg tttccaagga tattgtgaag ggcagcgtga agcaaatgag tcgcagtgtg
     5281 gtttttcatg acacggtgac ggcgattgct atcaattgcc aaggtatatt cttggttcaa
     5341 ggcaagcggt gcaaggactt caactgtatg aagggcttga ccatttgggg ctttctgaac
     5401 attggtcaca gtagccacaa tcttacctga ctcatccaag atttgtccgt agtcagctac
     5461 ctgtccaccc atttcagcat aaaatgacgt ttccgcaaag ataagagagg cagttccttc
     5521 tgaaacagct cctacttctg cattgtcagc aacgatagct accaatttag aagacaattg
     5581 gctagtattg tagttgaaga cactttctac agtgatgttt tgaagagttt cattttgcat
     5641 acccattgag ccacccttga cagctgacgc acgcgcgcgt tcttgctgtt ctttcatggc
     5701 tgcttcaaaa ccttcacggt ctacagtcat accagcttct tcagcgattt cttcagtcaa
     5761 ttcaactggg aacccataag tatcatagag tttaaagaca tcttgaccag caatgacaga
     5821 ttgacctttt tctttcaagt ctgccacaat gccttgggca aagtgttgac ctgagtgaag
     5881 ggtacgggca aatgattctt cttcgctctt aacgattttc tcaataaagt cacgtttctc
     5941 aagcacttct gggtagtagc tttccatgat ttttccaaca gttggaacca atttgtaaag
     6001 gaaaggctcg ttgataccca atttttgacc atgcatagaa gcacgacgga gaagacgacg
     6061 aagaacataa ccacgacctt catttcctgg aagggcacca tcaccgatag caaatgaaag
     6121 agaacgaatg tggtctgcga taaccttgaa gctcatgttg tcgccatctt ggtcataaac
     6181 cttaccagac aatttctcga cttcacggat aatcggcatg aagaggtccg tttcaaagtt
     6241 ggtcttagcc ccttggataa cggccaccaa acgctccaaa ccagcgcccg tatcaatgtt
     6301 cttatgtggc aattccttgt attcgctacg aggaacagca gggtctgcgt taaattgtga
     6361 caaaacgatg ttccagattt caatataacg gtcgttttca atatcttctg caagcaggcg
     6421 aagaccgata ttttctgggt caaaggcttc cccacggtca aagaagattt ctgtatctgg
     6481 tccagaaggt cccgcaccga tttcccagaa gttgtcctca attggaatca agtgacttgg
     6541 atccactccc acttcaatcc agcggttgta agaatcttta tcgtctggat agtaggtcat
     6601 gtaaagtttt tcagcaggga aatcaaacca ttcagggctt gtcaaaagct cataagccca
     6661 agtgatagct tcgtcacgga agtaatcccc gatagagaag ttccccagca tttcaaacat
     6721 ggtatggtga cgcgcagtct tccctacgtt ttcgatgtcg ttggtacgga tagccttttg
     6781 ggcattggta atacgtggat tttcagggat aatggtcccg tcaaagtatt tcttaagggt
     6841 tgctacccca gagttgatcc acaaaagagt tgggtcattt acaggaacca aacttactga
     6901 tggttctact gagtgacctt tggtcgccca gaaatcaagc cacatttggc gtacttgtgc
     6961 actagatagt tgtttcatat tgtctcctta ttcacttgtt taatgtgatt ggctttccag
     7021 catttccaca tagtcaatcg cgacacagag ggaaatgact aggtctgcat aagcgtcttc
     7081 aagaaccgtt acggtatagg tagaggtcag atggaagagt tccttcttaa tttccgcaat
     7141 caactgatcg cgatcatcca gcaatttgaa attcaaatcc cagatattgc cctcgatacg
     7201 aagacctaga ttatcaaact catacttatc tcgccagaag gtcaacttct tacgaatgac
     7261 aaaactcgag ccatcccgaa gctgaatctc aaaacgagga agcaaggtca agatttcttt
     7321 actgatctga ctgacttgtt caccagccgc atcatagatg gtaaaagttt tgggaatctt
     7381 aaaaaatgat ccctccacct gataggcaat ttctcccctg tcatccttga tagcgaagcg
     7441 ttcgcctcca agacgaaact tttgtttgac aagaaatgtt ttcatcaaca cctccaaaaa
     7501 tcaaaagaca agctcatatc acgaagggcg aaaaaccgcg gtaccacctt cattcaatga
     7561 acttgtcatt ctcttgttct tatgcaattg tatgattgag tagcatgact tcctagctta
     7621 gatggctcgc agcaccgcca tttctctgga ctaagacaag tgaaaatcaa ttctcaactt
     7681 tcttattata acgttttttt aagcttgcgt caactggaaa tgatctccgt tgaattagac
     7741 caattcccta catctctgat tactttttca ggatatattt tttcttactg ccatttttct
     7801 ttttatccca aattttcata ttactaaaca cagctactag aatatttcca aatataaagg
     7861 tgcctatcac ccaatatatg gactcagttg ttaggtattg tcgatccaag ccatcattta
     7921 aatggaatag tatagcagtt tggttaacaa tcataaaggt tggccagaaa ctttttttga
     7981 aaaaagtaga cattttcatt atttgttgcc gctttctgta aggttaatac tcaataaaaa
     8041 tcaaaaagca aactaggaag ctagcttcaa gctgtacttg agtacggcaa ggcaacgctg
     8101 acgtggtttg aagagtatag gcttagtata ctactaggca agcaaataag caaataaaca
     8161 aataaacaac tagaatagaa aaagataggg ctctaaaaac tgacttctat tccttaaaaa
     8221 cgaaccagct tgactgattc gtcttcttac gtttatctcc tacttccgat acattttaaa
     8281 ctgtaggaag aggtcgctat atttccctgt ccatttatgg tcaaatttct cataaacttc
     8341 taggtgtttc atggtttcaa catcgggata gaaggcctta tcttcctttg tttcctctgg
     8401 gagcaattcc ttcgctggta ggtttggtgt tgaatagccg acatactccg cattttggag
     8461 agcattttca ggtttcaaca taaagttgat aaaggcatag gctgagtctt gatttttaac
     8521 tgttttggga atgaccatat tgtcaaacca aagattgctg gcctctgtcg gtaccacata
     8581 acgtagattt tcattttttt ctaacatttg gctggcttca ccagagaagg tcacgccgat
     8641 tgcaacatta ttctgaatca tgtagccctt catctcgtcc gcaacgatag ccttgatatt
     8701 tggagtcagt ttgtagagct tatccactgt ctcttccaac tgctgcggat ccttggagtt
     8761 gaggctgtag ccgagggaat tgagtcctag tcccagcacc tcacgcgccc catcaaaaag
     8821 catgatagaa ttcttatact ccagcttcca aaggtcatcc caatgctcag gcgcttcatc
     8881 taccatggtt tcgttgtaga caattcctaa ggttccccag aagtaaggga tggagaattt
     8941 attacctggg tcaaaggact ggttgagaaa ctctggtccg atattttcga ttccttcaat
     9001 ttttgaataa tcaagcggaa ccaagaggtc ttcgtccttc atcttgttaa tcatgtattc
     9061 acttggaatg gcaatatcgt aggtcgttcc accctgcttt atcttagtgt acatggcttc
     9121 gttggagtca aaagcctcgt actgaacttg aattcctgtt tcttctgtaa actgagtcaa
     9181 gagttcagga tcgatatagt ctccccagtt atagataacc aatttttgac tatctcgact
     9241 attgatttta ctatctaaat gagtcgcaat tccccacaag acaaggataa tcgctgcaat
     9301 tcctgctaaa aatgaataga tttttttcat gcttgctcct ccttctcacg agagataaag
     9361 taataaccta caactaggat aatactaaag agaaagacta gagcagaaag ggcattgatt
     9421 tctagcgaaa tccccttgcg agcacgagag taaatctcga ctgatagggt tgaaaagcca
     9481 tttcctgtta caaagaaggt cacggcaaag tcatctaacg aataggtgaa ggccatgaaa
     9541 taaccagcaa tgatagacgg agtcaggtaa ggaagcatga tttccttaaa catctgaaat
     9601 tgactagctc ccaagtcata ggccgcatga atcatgtcgc cattcatttc cttgagtcga
     9661 ggcaagacca tcaagaccac gataggaatg gagaaggcca catgactaga tagaacggtc
     9721 aaaaagccaa gtgaaaactt gagttgggta aagagaatca agaagctagc accaatcata
     9781 acgtcaggcg caaccatgag gatattattg agtgatagaa aggcttcttg gtatttctta
     9841 cgagactggt agatgtaaat ggcaccaaaa gtcccgataa tggtcgctat caaggctgat
     9901 aggaaggcca agaaaaatgt ctgagccaaa atcagcatga gtctcccatc tccaaacatg
     9961 gtttcaaagt gagtccagct aaaacctgta aagctattca tatcatcacc agcattaaag
    10021 gcatagccaa tcaagtaaaa gataggcagg tagaggacca gaaagaccag tcccagataa
    10081 aggttggcaa attttttcat cgttctctcc tttccttagt cacccacatg gtgatgaaca
    10141 tggtcaggat gagaatcaca ccgatagttg aacccatacc atagttgtca ttggttagaa
    10201 aattctgctc aatagccgtc cccaaggtga taacgcggtt cccaccaatc aaacgggtca
    10261 gcatgaagag actcaaactt gggataaaga ccgactgaac cccacttcgc acaccgttca
    10321 tagatagaag gaagatgaca tgacggaagg tctcccactt agttgcacca aggtcgtaac
    10381 tagcattgat gagattatta tccatatcgt ctaagacatt gaaaatcggc aaaatcataa
    10441 aggggagctc gatgtagctt gcgacaaaga taaaggaaaa atcggtaaaa agcaactgtt
    10501 gtgaaccaat tccgataaat tccaagaatt ggttaataga gccattttga ccaaaaatcc
    10561 cgataaaagc ataggcttta aggagcaaat tgatccaggt aggaaggata atcagcatga
    10621 gccagagttg acggtgcttg agacgggtca aaaagagggc tgttggatag ctgataagca
    10681 aggtcacaaa ggtcacaatc cctgcataaa gcactgagtt gaaactcatt ttgaggtagg
    10741 tcaagttttg tgacgcaaag taagatttat aattttctaa actaaactgg ccttcaatgt
    10801 tgaaaaagga ttgtccgaaa atcaagacca agggtgccaa tacaaagagg gcaatccaaa
    10861 gcatgtaggg cactacaaag agtttagagc ttgttttctt catctctttc ctcctcgatc
    10921 gcattgatca gacctgcttc ttgctcttcg atttccacgt attcttcgat acgagcatcg
    10981 aactcttctt cggtttcatt gagacgcatg atgtggatgt cttctggttc aaagtccaga
    11041 ccgatttcct cacccacgat ggccttacgg gttgagtgga tcatccattc atttccaagt
    11101 tcgtcatagg cgataatttc ataatgcacc ccacggaaga gctgggtatc gaccttaact
    11161 tggagcttgc cttcttcagg aagggtaatg cgcaagtcct ctggacgaat aacgacctca
    11221 acaggttcat ttggcttcat cccaccatca accgcttcaa agcgtttgcc gttaaattcg
    11281 accaagtagt cctcaatcat ggtacctggc aagatgtttg actccccgat aaaggtggca
    11341 acaaagtggt tgattggctc atcgtagatg tccacagggg ttccagactg gacaatctcg
    11401 ccatcattca taacgaaaat ccagtcactc atggcaagag cttcttcctg atcgtgagtg
    11461 acaaagacaa aggtaatgcc caatcgttgt tgtaattcac gcaattcgta ctgcatgtct
    11521 gttctcaatt tcaagtccag cgctgataaa ggctcgtcca acaagaccac acggggttgg
    11581 ttgatgatag cacgggcgat ggccacacgc tgacgttgtc ctccagaaag tttgcggatg
    11641 gaacgttttt cataaccttc caactgaacc atcttgagaa cttccgctac acgctgctca
    11701 atttctttct tatcaatttt acgcaagcga agtggaaagg caacattttc aaacacattc
    11761 atatgtggga acaaggcata ggattggaag acggtatgta cgtcgcgctt gttggttgga
    11821 atatcattga tacgaacacc gtctagcatg atatctcctg tcgtcgcatc cagtaaacct
    11881 gcaataatgt ttaggatagt tgatttcccc gaaccagatg cacctagaag ggtgtagaat
    11941 ttcccttctt ccaactcaaa gttgatgtct ttgagaacct tggtgttgct gtcttcaaaa
    12001 actttagaga cgtttttgaa ttcgataatt ggttttttca attggcataa attccttctt
    12061 tttcatagat taaccgatcg gggctctgtc aggtccccac tacctcttgc agggagtaaa
    12121 accacctgca tacatcttcg ctaccgatag gctttcaccc aagatccgga cttctctttc
    12181 aagcgtaata cctgagtgtt ccttgacttt ttcgataacc gattggatca agtcctcgta
    12241 gtctttggcc gttccatctg cgacattgat cataaatcct gcatgctttt ctgacacttc
    12301 tacgccaccg atacgatagc ctttcaagcc agcttctgaa attaactgac ctgcaaaatg
    12361 cccgactgga cgcttaaaga ccgagccaca agatgggtat tccaaaggtt gcttgagttc
    12421 acgtaggtgc gtcaagcggt ccatttcctg cttgataacc tgatgggttc ctggagctag
    12481 ggcaaattta actgacaaga caactgcacc agactcctga atagctgaat ggcggtaacc
    12541 aaaagccaag tctttagcag acagggtttc gatttctcca tccttggtca agaccttaca
    12601 agactgcaag atgtgagcaa tctcgccacc ataggcaccc gcattcataa agacagcacc
    12661 gccaacgctt cctggaatac cacaagcaaa ctcaaagcca gttaaactat gacggagggc
    12721 aatgcgagtt gtttcaatca agttagcccc agcttctgct tcaatggtat agccatcaac
    12781 agaaacgtta ttgagcttgt cacacaagat gacaaatcca cgaatcccac catcacgaac
    12841 gatgatattg cttgcattgc caagaaccat ccaagggata ttttcttggt tggcaaattt
    12901 cacaacgcga gccaactcaa aacgatttcg tggaaagacc aaataatcag cctctccacc
    12961 tacttttgta taactatagc tatgcaaggg ttccttaaaa cggatatcaa ttccttctaa
    13021 gatttcaagc attttttctc ttacagacat gtcactcttc cttttacaaa attcattcca
    13081 ttataccatt tttagagaca tttgacgacc ataaaaatac cttgtttgga ttttgcataa
    13141 gaaaaagagg ttcccccctt tttatgattt tttacaaaag atttccttgg ttccataggc
    13201 gaccagaacg agctccagtg ctagaatcac ttcaaccaag actggatttg tcaaccagcc
    13261 tacttggaaa agagatggtg ccagatcaaa gaaggcatgc aagccatagg ctgctaggag
    13321 ataaatccat ttcttctggc gaacagcttg gtaaacccaa actgtcaaaa gtaattggaa
    13381 accaagcgcc aagattcgct caaaaccaag caaataaatc tgccagaccg aaagtgactg
    13441 aatggttttt aacatatttt cagacagtaa ttgcataacc tgtggattct gagtttgaac
    13501 tgccgaaaga acgatgtaaa gattgagtaa actaataagg cctagaaaaa tcaactccaa
    13561 gccaccatgc cctaggccat aggccaaggc atctgccttt tccaaacttc tctttttctc
    13621 caaccatttg aagaaaacaa gacgagccgt ttcctcaaaa aatgctgcca tggctaggcc
    13681 atagataata tagataagcg gatgatcttg caagagggca atactaccgt ctttttgagg
    13741 atgcaaaatc aagatatgca ccagtttttc caaaatctgc gaagagacaa agaaagcgac
    13801 tgcacccaag cccaagacag ctagattaat ctggtatttc tttttggcaa accaaatgct
    13861 tcctatcaga aaagctagca acagcaacat ggtaataatg atatgaatgg tcattttctt
    13921 ctcctattct gccttttcaa tatctttttt catctcgtca acattgaact tagcaaacaa
    13981 gtattgacgg tcttggactg ggaaacgttg gtccaactgg tcaactgctc ccacctcgat
    14041 aatgccttcc ttgatgacaa aatccatgac atgtccaccg aaggtcaaat catctgatat
    14101 gaagtgcaga tggtagcctg ccacactgac cccatggaaa atctcaggcg tccagaaacc
    14161 aacaatagtc cccgcaacat tgtcacgact atattccggt tgatgggttg cgacatcagc
    14221 aaacttggta tcgggtgttg acttaggaat catacgcaca tgcatatgtg aaaattcccc
    14281 ccgaatcttg atagagcgga aaagattttc cccatcataa taagactcaa ttcgttcttt
    14341 caattccttg tctgtcatct caaagcgctg gcggaaaatg acctctgcct gatgcggtac
    14401 cactgcagcg taaggaataa gggcatctgg tgacacttcc acaatttctg gctggtctcc
    14461 tgaccctttg gcctgataag ccttgccatc caagacaatc aattccccat caatggaatc
    14521 caaggttccc aaaccaaggt caccatgttc tagcaattct cctactgtca tagtaccacc
    14581 ataaaggcca gccatcaagg ctccaagagt attgtattga aataatttca ctggttcctg
    14641 cacgttctta tccattcact ttcttgtctg ttattctata aatcttactc ctaagtatac
    14701 cacatttgcc cctagatgtg aacgagagaa acgctctaga cattgccaag aaggaaaaaa
    14761 aagggtacaa tgtaacaaaa tcaagggagg tctggaatga agaaacaaag caagtacaaa
    14821 gaggtcgttt cctatctgaa aaatggtatc gagtctgaac gatttccgac gggtagtcgc
    14881 ctgccttcta tccgtcaact gagccttgac tttcactgca gcaaggacac cattcaacga
    14941 gccctgctgg aattacggca cgaacaatac ctctatgcca agcctcagag tggctactat
    15001 gtattagaac aagggcaaca tcaagaccta gaaatcgagg ttaccgacga acatgccagt
    15061 gcctatgacg atttccgact ctgtgtcaat gaaaccttga ttggacgaga aaactacctc
    15121 ttcaactact atgacaatca agaaggatta gaagacctaa gacagtccat tcacaaactc
    15181 ctatttgagc aagctctcta ctgcaaggct aaccaactag tactgacttc tggaacccaa
    15241 caagccttgt ttatcctctc tcaaatatcc tttcctagac aagccaagga aatcttggtg
    15301 gaacagccaa cctaccatcg gatgaatcgc ctcttgattg cacaggggct ggactatcaa
    15361 acgattgaac gaggcattga tgggattgac ttggaggagc tggaaggcca cttcaaaaca
    15421 ggaaaaatta aatttttcta caccattcct agatttcact atcctctggg acattcctat
    15481 tctgagcaag acaaacgatc tattcttaac ttagctgcca agtatgatgt ctatatcgta
    15541 gaggacgatt atctgggtga tttggactcc aagaagggcc aaaccttcca ctatcttgat
    15601 acagaggagc atgtcattta tatcaagtcc ttctcgacca gcctttttcc tgcccttcgt
    15661 attacagcac tcattcttcc aaatgctatc aaagaagcat ttgtggccta caaaaatatc
    15721 ctagactacg acagcaacct cattatgcaa aaggccctgt cactctatat tgacagtcaa
    15781 ttgtttgaaa aaaatcgttt ggctcgcttg accaatcatg aatcttacca aaaacaaatc
    15841 gaggaaagga taactaaaac accttgtccc cttcctcatt atcccctaca cgatggttta
    15901 ttgctagacc tgagacagta tcctaaaatc gccagtctca aacacagtca actgggcttg
    15961 gacttctttg aagaggccta tttaagcacc tgtccttatc aatttgccaa ggtgtcccta
    16021 gacaatctgg aaaatgtttt aaactattta aaagcagaat tggaatgaca tccaactctg
    16081 ctttttctta ttcttcaact tcagttagac ttgctgcttt ttcaagatag ctttggtaag
    16141 ttccttcatc cttaagtttt tggatgacct tgtctaccac ttctttcaaa tcatcactat
    16201 tttttctaag agcaacggca ttggcgtcgc cgtccttcat cttcaagctg acagttgcga
    16261 cagctaagcc agcgttttta gcagcataac taagtgcaac aggctcatcc atatgaacag
    16321 catctatttt tccagtctgc aattcattga ctgcttcacc catattagtt agggaagtta
    16381 attgaacttt tggcaattgt tccttgacca ttgattctgg aacagtccct ttttgggctg
    16441 caatattagc actttctagg ctagttaaat ccttgtattt ttccacatca gccttacgaa
    16501 ccaagaaact aatcttgttt tcatagtatg ggattgaaaa atcaaagact tcttttctct
    16561 cgtcagtagc actaattcct gcaactgcta ggtcagcctt accagtttga agactggtca
    16621 aaacattgtc aaaactcatg cttgagattt ccaacttaac cccaagttca tcagcgatag
    16681 cctgagccat gtcgatgtct gcaccgacta cctggttctt tccatcaacc aatgattgaa
    16741 attcaaaggg tgcatagtca ggactggttg ccacaactaa tttccctttt tgtttgatag
    16801 catccacagc agactgagaa ccattagaac ctgactgaca agctactaag aagaaacttg
    16861 caagaaaatt acataaaaca aatatccatt tttttgattt cataaataaa caacctctct
    16921 gttaattttg tataattat
//
LOCUS       DBEJAU010000047        14625 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC323 isolate 683620
            SAMN38261939-rid24807223.denovo.047, whole genome shotgun sequence.
ACCESSION   DBEJAU010000047 DBEJAU010000000
VERSION     DBEJAU010000047.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261939
            Sequence Read Archive: SRR26833919
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 14625)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14625)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576303.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576303.1
            Genome Coverage       :: 154x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/19/2025 01:05:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,121
            CDSs (total)                      :: 2,078
            Genes (coding)                    :: 1,943
            CDSs (with protein)               :: 1,943
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 36
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 72 of 135
            Pseudo Genes (incomplete)         :: 63 of 135
            Pseudo Genes (internal stop)      :: 51 of 135
            Pseudo Genes (multiple problems)  :: 46 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14625
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261939-rid24807223.denovo.047"
                     /strain="GPSC323"
                     /isolate="683620"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            468..1589
                     /gene="mnmA"
                     /locus_tag="ACL29Z_001664"
     CDS             468..1589
                     /gene="mnmA"
                     /locus_tag="ACL29Z_001664"
                     /EC_number="2.8.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006153390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016740 - transferase activity [Evidence
                     IEA];
                     GO_function: GO:0016783 - sulfurtransferase activity
                     [Evidence IEA];
                     GO_process: GO:0008033 - tRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA 2-thiouridine(34) synthase MnmA"
                     /protein_id="HGR0069940.1"
                     /translation="MSDNSKTRVVVGMSGGVDSSVTALLLKEQGYDVIGIFMKNWDDT
                     DENGVCTATEDYKDVVAVADQIGIPYYSVNFEKEYWDRVFEYFLAEYRAGRTPNPDVM
                     CNKEIKFKAFLDYAITLGADYVATGHYARVARDEDGTVHMLRGVDNGKDQTYFLSQLS
                     QEQLQKTMFPLGHLEKPEVRRLAEEAGLSTAKKKDSTGICFIGEKNFKNFLSNYLPAQ
                     PGRMMTVDGRDMGEHAGLMYYTIGQRGGLGIGGQHGGDNAPWFVVGKDLSKNILYVGQ
                     GFYHDSLMSTSLEASQVHFTREMPEEFTLECTAKFRYRQPDSKVTVHVKGEKTEVIFA
                     EPQRAITPGQAVVFYDGEECLGGGLIDNAYRDGQVCQYI"
     gene            1730..2185
                     /locus_tag="ACL29Z_001665"
     CDS             1730..2185
                     /locus_tag="ACL29Z_001665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HGR0069941.1"
                     /translation="MTQQDFRTKVDNTVFGVRATALIVQNHKLLVTKDKGKYYTIGGA
                     IQVNESTEDAVVREVKEELGVKAQAGQLAFVVENRFEVDGVSYHNIEFHYLVDLLEDA
                     PLTMQEDEKRQPCEWIDLDKLQNIQLVPVFLKTALPDWEGQLRHIHLEE"
     gene            2195..4108
                     /gene="mnmG"
                     /locus_tag="ACL29Z_001666"
     CDS             2195..4108
                     /gene="mnmG"
                     /locus_tag="ACL29Z_001666"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000221902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0002098 - tRNA wobble uridine modification
                     [Evidence IEA];
                     GO_process: GO:0008033 - tRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA uridine-5-carboxymethylaminomethyl(34)
                     synthesis enzyme MnmG"
                     /protein_id="HGR0069942.1"
                     /translation="MTYHFTEEYDIIVIGAGHAGVEASLAASRMGCKVLLATINIEML
                     AFMPCNPSIGGSAKGIVVREVDALGGEMAKTIDKTYIQMKMLNTGKGPAVRALRAQAD
                     KELYSKEMRKTVENQENLTLRQTMIDEILVEDGKVVGVRTATHQEYAAKAVIVTTGTA
                     LRGEIIIGDLKYSSGPNHSLASINLADNLKELGLEIGRFKTGTPPRVKASSINYDVTE
                     IQPGDEVPNHFSYTSRDEDYVKDQVPCWLTYTNGTSHEIIQNNLHRAPMFTGVVKGVG
                     PRYCPSIEDKIVRFADKERHQLFLEPEGRNTEEVYVQGLSTSLPEDVQRDLVHSIKGL
                     ENAEMMRTGYAIEYDMVLPHQLRATLETKKISGLFTAGQTNGTSGYEEAAGQGIIAGI
                     NAALKIQGKPELILKRSDGYIGVMIDDLVTKGTIEPYRLLTSRAEYRLILRHDNADMR
                     LTEMGREIGLVDDERWARFEIKKNQFDNEMKRLDSIKLKPVKETNAKVEEMGFKPLTD
                     AVTAKEFLRRPEVSYQDVVAFIGPAAEDLDDKIIELIETEIKYEGYISKAMDQVAKMK
                     RMEEKRIPANIDWDDIDSIATEARQKFKLINPETIGQASRISGVNPADISILMVYLEG
                     KNRSISKTLQKSK"
     gene            complement(4487..6166)
                     /locus_tag="ACL29Z_001667"
     CDS             complement(4487..6166)
                     /locus_tag="ACL29Z_001667"
                     /EC_number="3.1.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009729634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0004540 - RNA nuclease activity [Evidence
                     IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease J"
                     /protein_id="HGR0069943.1"
                     /translation="MAYTLKPEEVGVFAIGGLGEIGKNTYGIEYQDEIIIVDAGIKFP
                     EDDLLGIDYVIPDYSYIVDNIDRVKAVLITHGHEDHIGGIPFLLKQANVPIYAGPLAL
                     ALIRGKLEEHGLLRNAKLYEINHNTELTFKNLKATFFRTTHSIPEPLGIVIHTPQGKI
                     VCTGDFKFDFTPVGEPADLHRMAALGEEGVLCLLSDSTNAEVPTFTNSEKVVGQSIMK
                     IIQGIEGRIIFASFASNIFRLQQATEAAVKTGRKIAVFGRSMEKAIVNGIDLGYIKAP
                     KGTFIEPNEIKDYPAGEVLILCTGSQGEPMAALSRIANGTHRQVQLQPGDTVIFSSSP
                     IPGNTTSVNKLINIISEAGVEVIHGKVNNIHTSGHGGQQEQKLMLCLIKPKYFMPVHG
                     EYRMQKVHAGLAVDTGVEKDNIFIMSNGDVLALTADSARIAGHFNAQDIYVDGNRIGE
                     IGAAVLKDRRDLSEDGVVLAVATVDFKSQMILSGPDILSRGFVYMRESGDLIRQSQRI
                     LFNAIRIALKNKDASVQSVNGAIVNAIRPFLYENTEREPIIIPMILTPDEE"
     gene            complement(6168..6401)
                     /locus_tag="ACL29Z_001668"
     CDS             complement(6168..6401)
                     /locus_tag="ACL29Z_001668"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002947111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003899 - DNA-directed 5'-3' RNA
                     polymerase activity [Evidence IEA];
                     GO_process: GO:0006351 - DNA-templated transcription
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-dependent RNA polymerase subunit epsilon"
                     /protein_id="HGR0069944.1"
                     /translation="MIYKVFYQETKERSPRRETTRALYLDIDTSSELEGRITARQLVE
                     ENRPEYNIEYIELLSDKLLDYEKETGAFEITEF"
     gene            6681..6896
                     /locus_tag="ACL29Z_001669"
                     /pseudo
     CDS             6681..6896
                     /locus_tag="ACL29Z_001669"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000282487.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(7220..7372)
                     /gene="cibB"
                     /locus_tag="ACL29Z_001670"
     CDS             complement(7220..7372)
                     /gene="cibB"
                     /locus_tag="ACL29Z_001670"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000977347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fratricide two-peptide bacteriocin subunit CibB"
                     /protein_id="HGR0069945.1"
                     /translation="MMKDLNNYREISNKELQEIKGGFGVGVGIALFMAGYTIGKDLRK
                     KFGKSC"
     gene            complement(7374..7559)
                     /gene="cibA"
                     /locus_tag="ACL29Z_001671"
     CDS             complement(7374..7559)
                     /gene="cibA"
                     /locus_tag="ACL29Z_001671"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000180803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fratricide two-peptide bacteriocin subunit CibA"
                     /protein_id="HGR0069946.1"
                     /translation="MTNFDILDNQFLSLSENELSDIDGGLAPLVIFGVAVSWKAIAGG
                     TALIGSGLAAGYFLGGD"
     gene            7737..8420
                     /gene="tsaB"
                     /locus_tag="ACL29Z_001672"
     CDS             7737..8420
                     /gene="tsaB"
                     /locus_tag="ACL29Z_001672"
                     /EC_number="2.3.1.234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000865689.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0002949 - tRNA threonylcarbamoyladenosine
                     modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     dimerization subunit type 1 TsaB"
                     /protein_id="HGR0069947.1"
                     /translation="MKVLAFDTSSKALSLAILEDKQVLAETTINIKKNHSITLMPAID
                     FLMASLDWTPKDLDRIVVAEGPGSYTGLRIAVATAKTLAYTLNIELVGMSSLLALVPH
                     QQEGLFVPLMDARRNNVYAGFYENAKPVMAEAHLSFEEVLEKVKGTSQVTFVGEVGPF
                     VEQIQKHLPRTDYKETLPNAANLALLAWDKEADSLHDFVPNYLKRVEAEENWLKNHTE
                     SGESYIKRL"
     gene            8417..8854
                     /gene="rimI"
                     /locus_tag="ACL29Z_001673"
     CDS             8417..8854
                     /gene="rimI"
                     /locus_tag="ACL29Z_001673"
                     /EC_number="2.3.1.266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000569806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008999 -
                     peptide-alanine-alpha-N-acetyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0036211 - protein modification process
                     [Evidence IEA];
                     GO_process: GO:0042254 - ribosome biogenesis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal protein S18-alanine
                     N-acetyltransferase"
                     /protein_id="HGR0069948.1"
                     /translation="MIEIKRIQQQPDLAQAIYAVIAAVYLVSPWTLEQIQADLSQDQT
                     WYALAYDGAEVIGFLAVQENLFEAEVLQIAVKGAYQGQGIASALFAQLPTDKEIFLEV
                     RKSNQRAQAFYKKEKMAVIAERKAYYHDPVEDAIIMKREIDEG"
     gene            8844..9854
                     /gene="tsaD"
                     /locus_tag="ACL29Z_001674"
     CDS             8844..9854
                     /gene="tsaD"
                     /locus_tag="ACL29Z_001674"
                     /EC_number="2.3.1.234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002896630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0002949 - tRNA threonylcarbamoyladenosine
                     modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     transferase subunit TsaD"
                     /protein_id="HGR0069949.1"
                     /translation="MKDRYILAFETSCDETSVAVLKNDDELLSNVIASQIESHKRFGG
                     VVPEVASRHHVEVITACIEEALAEAGITEEDVTAVAVTYGPGLVGALLVGLSAAKAFA
                     WAHGLPLIPVNHMAGHLMAAQSVEPLEFPLLALLVSGGHTELVYVSEAGDYKIVGETR
                     DDAVGEAYDKVGRVMGLTYPAGREIDELAHQGQDIYDFPRAMIKEDNLEFSFSGLKSA
                     FINLYHNAEQKGESLSTEDLCASFQAAVMDILMAKTKKALEKYPVKTLVVAGGVAANK
                     GLRERLAAEITDVKVIIPPLRLCGDNAGMIAYASVSEWNKENFAGWDLNAKPSLAFDT
                     ME"
     gene            complement(9894..11200)
                     /locus_tag="ACL29Z_001675"
                     /pseudo
     CDS             complement(9894..11200)
                     /locus_tag="ACL29Z_001675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011680908.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
     gene            complement(11536..12227)
                     /locus_tag="ACL29Z_001676"
                     /pseudo
     CDS             complement(11536..12227)
                     /locus_tag="ACL29Z_001676"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001839528.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing N-terminus and C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            12470..13675
                     /locus_tag="ACL29Z_001677"
     CDS             12470..13675
                     /locus_tag="ACL29Z_001677"
                     /EC_number="2.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001200043.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016757 - glycosyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HGR0069950.1"
                     /translation="MQYSCGKININIPDGYGDIKDIVFSAHIIVRYNNGHCGGIDPHI
                     IGLCKKQIRRMSLYPILIIVSRDSKVIDDYKNLDIAYVDCTQCSNNFETALHVKNILK
                     LLKIQLIHCHGYSTNYFLYMLKKLDKNGFGKVKTVITCHGWVEYNLKKKFLTYFDFWT
                     YSMGDAFICVSETMKKRLESIIKNKKIVAINNGINVSNSDLDVVGVQDFKKEFCIPNN
                     KKIICYVGRLDPEKRPDRFLEFAEKLFLVREDVIFIMAGNGSMWAALKEKICHLKCRD
                     NFRLLGEIYPATIVYQISDLLYIPYDTEGIPMCVLESMSQGTPVLASNVGGLSEIIEH
                     RVDGFLFEKEDVEGVCACANFLLNDSEYLKYIGENSKSKIRKHFSVQKMFVETMRVYD
                     ELLEKSSHG"
     gene            13668..14621
                     /locus_tag="ACL29Z_001678"
     CDS             13668..14621
                     /locus_tag="ACL29Z_001678"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397244.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HGR0069951.1"
                     /translation="MDRNIDQELVSIIIPTHNRYESLIRAVKSCLHQSYKNIEVIIID
                     DNYSNVNLRNKIIHQFGYTNHRIKLILSNEDLGATNARNIGIKNSRGKYISFLDDDDE
                     YMPDRILKLMACFKKSRMKNLALVYSYGIIIYPNGTREEEKTDFVGNPLFVQMVHNIA
                     GTSFWLCKKEVLELINGFEKIDSHQDGVVLLKLLAQGYQIDIVREFLVNYYAHSKENG
                     ITGVTQKTINADEEYYNYCRKYFNLLSFNERILVTKKYYSLNIKRLLLIGDKCKALKV
                     IKKAREEKIFNEFLFLKYMLLYYFGFFYCIYDNYVQLKFRK"
BASE COUNT         4369 a         2671 c         3314 g         4271 t
ORIGIN      
        1 aggtgccctt gcagtcaaca caactgtaga tggctataaa gtcaatgcca atggtgaatg
       61 ggtttaagcc gattaaatta aatcatgtta agaacatttg acattttaat tttgaaacaa
      121 agataaggtt cgattgaata gatttatgtt cgtattcttt aggtacctat cttatgattt
      181 caggaaatgt cattaaaaaa acgactcatt ttctctaact tgaaaaatag attagagaaa
      241 atgggttgtt ttatttatta tagttatttg aatgaagata agaagaaggt atactcacat
      301 cattcacata atctgtatat tgactataag ttttaaaaaa caatttttaa gctcttcctt
      361 gtcttctcta accaagcgtg ttataatgaa tactgctcaa gcgaccttca atcgtgaagc
      421 acacacgacc ttcaatcgtg aataaacgaa tagatgggag acttaccatg agtgataact
      481 ctaaaacacg tgttgtcgtg gggatgagtg gtggtgttga ttcgtcggtg acggctcttt
      541 tgctcaagga gcagggctac gatgtgatcg gtatcttcat gaagaactgg gatgacacag
      601 atgaaaacgg cgtctgtacg gcgaccgaag attacaagga tgtggttgcg gtggcagacc
      661 agattggcat tccctactac tctgtcaatt ttgaaaaaga gtactgggac cgcgtttttg
      721 agtatttcct agcggaatac cgtgcagggc gcacgccaaa tccggacgtt atgtgcaaca
      781 aggaaatcaa gttcaaggcc tttttggact atgccataac cttgggggca gactatgtag
      841 cgactgggca ttatgctcga gtggcgcgtg atgaggatgg taccgttcac atgcttcgtg
      901 gcgtggacaa tggcaaggat cagacctatt tcctcagcca actttcgcaa gaacaacttc
      961 aaaaaaccat gttcccacta ggacatttgg aaaagcctga agtacgcaga ctagcagaag
     1021 aagcaggcct ttcgactgct aagaagaaag actcgacagg gatttgcttt atcggagaaa
     1081 agaactttaa aaactttctc agcaactacc tgccagctca gcctggtcgc atgatgactg
     1141 tggatggtcg cgatatgggc gagcatgcag gtcttatgta ctatacaatc ggtcagcgtg
     1201 gcggactcgg tatcggtggg caacacggcg gtgacaatgc cccttggttc gttgtcggaa
     1261 aagatctaag caagaatatt ctctatgtag gacaaggatt ctaccatgat tcgctcatgt
     1321 caactagcct agaagccagt caagtccact ttactcgtga aatgccagaa gagtttacgc
     1381 tagaatgtac ggctaaattc cgttaccgtc agcctgactc taaggtgacc gttcatgtca
     1441 aaggagaaaa gacagaggtc atctttgcgg aaccacaacg cgcgattaca ccaggacagg
     1501 cagttgtctt ttacgatggc gaagagtgtc taggtggcgg tttgattgac aatgcttacc
     1561 gcgatggaca agtttgtcag tacatttaga ttgacaaatt ttctcaattt gctacaataa
     1621 taacagcaat agaaatgatg gtcaaagctc atggatgttg caggcttttt tgtcctgcac
     1681 ttctttgtag ttttgactgt ttttgtgtcg tttaagggaa aggacaagaa tgactcaaca
     1741 agactttcgg acaaaagtag acaatacggt ttttggtgtt cgggctacag ccttgattgt
     1801 ccaaaatcac aagcttctag ttaccaaaga caagggcaag tattacacta ttggaggtgc
     1861 gattcaagtc aatgaaagca cggaagacgc ggtagtccgt gaagtgaagg aagaactggg
     1921 tgtcaaagct caagctgggc agctagcttt tgtggttgaa aatcgttttg aagtggacgg
     1981 cgtttcctat cacaatatcg agtttcatta tctggtggat ttgcttgaag atgccccgtt
     2041 gaccatgcag gaagatgaga aaaggcagcc ctgtgagtgg attgacttgg ataagctcca
     2101 gaatatccag ctagttccag tctttttaaa aacagcccta ccagattggg aaggccaact
     2161 aagacacatt catcttgagg aataggagag aaacatgact tatcatttta ctgaagaata
     2221 cgatattatt gtaattggtg cgggacacgc tggggttgag gcttccttgg ccgctagccg
     2281 tatgggctgt aaggtcctgc ttgcgaccat caatattgaa atgctggctt tcatgccttg
     2341 taatccctct atcggtggtt ctgccaaggg gattgtcgtg cgtgaagtcg atgccctcgg
     2401 tggcgagatg gccaaaacca ttgacaagac ttacatccag atgaagatgc taaacacagg
     2461 gaaggggcca gctgtccgtg cccttcgtgc gcaggctgac aaggaacttt actctaagga
     2521 gatgcgcaag acggttgaaa accaagaaaa tctgaccctt cgtcaaacca tgattgatga
     2581 gattttggtg gaagatggca aggttgtcgg tgtgcgtaca gccacccatc aagaatatgc
     2641 tgctaaggct gttattgtga cgacagggac tgctctccgt ggggaaatta tcatcggaga
     2701 cctcaagtac tcatcaggtc ctaaccacag cttggcttct attaacctag ctgataatct
     2761 caaggaatta ggactcgaaa tcggtcgttt caagacagga acccctccac gtgtcaaggc
     2821 ttcttctatc aactacgacg tgacagaaat tcagccagga gacgaagtgc ctaatcattt
     2881 ctcatacact tcacgtgatg aggattatgt caaagatcaa gtgccatgct ggttgaccta
     2941 caccaatggt accagtcatg agattatcca aaacaacctc caccgtgcgc ctatgtttac
     3001 aggtgtggtc aagggagtgg ggcctcgtta ctgtccgtcg attgaagaca agattgtgcg
     3061 ctttgcggac aaggaacgtc accaactctt ccttgagcca gaagggcgca atactgagga
     3121 agtctatgtt caaggacttt caaccagtct gcctgaggat gtccagcgtg acttggttca
     3181 ttccatcaaa ggtttggaaa atgcagagat gatgcggaca ggttatgcta ttgagtatga
     3241 tatggtcttg cctcatcagt tgcgtgcgac tttggaaacc aagaaaatct caggtctctt
     3301 cactgctggt cagacaaatg gaacatcagg ttacgaagaa gctgctggcc aagggattat
     3361 cgcgggtatc aatgcggctc tgaaaatcca aggcaagcct gaattgattt tgaagcgcag
     3421 tgatggttat atcggggtga tgatcgacga cttggtgacc aagggaacca ttgaacccta
     3481 ccgtctcttg accagtcgtg ctgaataccg tctcattctt cgtcatgaca atgctgatat
     3541 gcgcttgact gagatgggac gcgagattgg ccttgtggac gatgaacgct gggctcgttt
     3601 tgaaatcaag aaaaatcaat ttgataatga gatgaagcgc ctagacagta tcaaacttaa
     3661 gccagtcaag gaaaccaatg ccaaggttga ggagatgggc ttcaaaccct tgaccgatgc
     3721 agtgacagcc aaggaattcc ttcgccgtcc agaagtttct taccaagatg tggtggcctt
     3781 catcggacca gctgcagaag acttggatga caagattatc gaattgattg aaacagaaat
     3841 caagtatgaa ggctatattt ccaaagccat ggaccaggtt gccaagatga aacgcatgga
     3901 agaaaaacgc attccggcca atatcgactg ggatgacatt gattctatcg caaccgaagc
     3961 ccgtcagaag ttcaaactca tcaatccaga aaccatcggc caagccagcc gtatttcggg
     4021 agtaaaccca gcagatattt ctattttgat ggtgtatctg gaaggtaaaa atcgtagtat
     4081 ttctaaaact cttcaaaaat caaaatgata cgtcgtaggc ttcttacgaa tgagttcaaa
     4141 gcttggcttt gattcatctc caacctccca tagttccccg aactatggga gctaactcaa
     4201 gttatgcatt ttcctagcct tctggtctga ttttcattga gttttaatct aaaaagaaag
     4261 catagagaaa aacagctccg aagacggggc tgttttgttg atttgtactc aatgaaaatc
     4321 aaagagcaaa ctaggaagct agccgtaggt tgctcaaagc actgctttga ggttgtagat
     4381 agaactgacg aagtcagctc aaaacacagt tttgaggttg tggatagaac tgatgaagtc
     4441 agtaacatat atacggcaag gcgaagctga cgtggtttga agagtattat tcttcatctg
     4501 gtgtgaggat catcgggatg atgatcggtt cacgttcggt attttcatag aggaaggggc
     4561 gaatagcgtt gacaatggca ccattgacag attgcacgct agcatcctta tttttcagtg
     4621 cgatacgaat ggcattgaag aggatacgct ggctttggcg aatcaagtcg ccagactctc
     4681 tcatgtagac aaagcctcgg ctgaggatgt ctggaccaga tagaatcatc tgcgatttga
     4741 agtcaacagt tgcgactgcc agaacgacac cgtcttcaga tagatcgcga cgatctttga
     4801 ggacagctgc gccaatttca ccgatacgat ttccatcgac atagatatct tgggcgttga
     4861 aatggcctgc gatacgagct gagtcagcag taagggcaag cacatcgcca ttgctcatga
     4921 taaagatatt gtccttctca acaccagtat ccactgctag tccagcgtgg actttttgca
     4981 tgcggtattc accgtggaca ggcatgaagt attttggctt aatcaagcag agcatgagtt
     5041 tttgctcttg ctgaccaccg tgtccagatg tatggatatt gttcacttta ccgtggataa
     5101 cttcgacacc agcttcagaa atgatgttaa tcagcttgtt gacgctagta gtgtttccag
     5161 ggatgggact agaagagaag ataacggtat cacctggttg taattgtact tgacggtggg
     5221 ttccgttggc gatacgagag agggctgcca taggctcacc ctgactacct gtacagagga
     5281 taagaacttc tcctgcagga taatctttga tttcatttgg ctcgataaag gttcccttag
     5341 gagctttgat gtagccaaga tcgattccgt tgacaatggc cttttccata gaacgaccaa
     5401 agaccgcaat cttgcgtcca gtcttaacag cagcttctgt tgcctgctgg agacggaaga
     5461 tatttgaggc aaaggatgca aagatgatac gtccttcaat accttggata atcttcataa
     5521 tggactgacc aacgactttt tcagagttgg taaaggttgg tacttccgca tttgtcgagt
     5581 cagacaggag acagagcacg ccttcttcac caagcgcagc catacgatgc aagtccgcag
     5641 gttctccaac tggagtaaag tcgaacttaa agtcacccgt acagacgatt ttcccttgag
     5701 gagtatgaat gacaatcccc aaaggctctg gaatagagtg agtcgttcta aagaaagttg
     5761 ccttgagatt tttaaaggtc aactcggtgt tgtggttgat ttcgtaaagt ttggcgttgc
     5821 gcaagaggcc gtgttcttcg agtttcccac ggatcaaagc caaggcaagc ggtccagcat
     5881 aaatagggac atttgcttgc ttgagtagga acggaatccc accaatgtgg tcctcgtgtc
     5941 cgtgtgtgat taaaacagcc ttgacgcggt cgatattgtc tacgatgtaa gagtagtcag
     6001 gaatgacata gtcgatacca agcaagtcat cttctgggaa tttaatccca gcatcgacga
     6061 tgataatctc gtcttggtat tcaattccgt aagtgttttt cccgatttct cctagaccac
     6121 cgatggcaaa aacaccaact tcttcaggtt taagagtgta ggccatatta gaactccgta
     6181 atttcgaagg cgccagtttc tttttcgtaa tcgagcaatt tgtcagacaa gagttcgata
     6241 tattcgatat tgtactctgg gcgattttct tcgacaagtt ggcgagcagt gatacggccc
     6301 tcaagttctg agctggtatc gatgtctagg taaagcgcgc gtgttgtttc acggcgtggg
     6361 ctacgttctt ttgtttcttg ataaaaaact ttgtaaatca tatagttcct ttctatttac
     6421 aggtcagctt attccaaact tttagcagat atttgcttga tttcattcca ttttgtgtct
     6481 agattgacct tgattcgtta caattatttc aattatacca caaaatgaaa aattagtaaa
     6541 agacggaaac gagaaagtta ggggacgatt tctttggtaa tcgtttgcaa aaataaagaa
     6601 aatgtattat gttgataacg gaagtgaaat ttattgcttg tcataattcc atatagattt
     6661 taagtcaagg aggttgccct atgtataact tatttgcttt tgctatcgga gttcgtttgt
     6721 taacttttat cgtttttgtt gcttgcgttt atggaggaaa tcttctattt gccaaactgg
     6781 aacgatgaca aaccaagttc ttgtggaaaa ttacctttgt gactctctac tcgctttttc
     6841 tcctccttgt aacctatgtc gtttggtttg tattttactt tggattaaat gcttagatgc
     6901 cctgctcatg ctagggcatt tttgtttgga gataagaaga caatagattt acgatacgaa
     6961 aagtccaccc catctatcca gatgaggcgg tttttgtatt ttttagaaat gacatgataa
     7021 tggtattttc agagcttatt agttttatgg taatcattct tctgatcaaa aatagagttg
     7081 aagcataaaa ataaaacaat acaaacagat aaatcaattg gtaaagggat agtagtaatg
     7141 ttcaaatcat tgagaatgct gagcaaactg taagagatga agacaataaa atttatcctt
     7201 ataaaaatat gtttcttatc tagcatgact taccaaactt tttacgaagg tcttttccaa
     7261 tggtataacc tgccataaat aaagcgatac caacacctac accaaagcca cccttgattt
     7321 cttgcaattc cttattagaa atttcacgat agttgttcaa atctttcatc atattaatct
     7381 cctcctaaaa aataaccagc tgccaaacca gaacctataa gtgctgttcc acctgcaata
     7441 gccttccaag atactgctac tccaaagata accaagggag cgagaccgcc atcaatatct
     7501 gataattcat tttcagataa ggataaaaat tgattgtcaa gaatgtcaaa atttgtcatt
     7561 gaactttcct ccttttttct tgttcacttt tatattcgga aaagaaaagg aaaagtgagc
     7621 atttttttaa attattttta gttaagtgag ggcactcttg tctgggggca aagaaaattc
     7681 ccatgtgcca gcttttgtag tataatagta agcagacaaa aagataggaa tgtgttatga
     7741 aagtattagc ttttgatacg tccagcaagg ctctttctct ggctatttta gaggataagc
     7801 aggttcttgc cgagacgacg attaatatta agaaaaatca cagtattact cttatgcctg
     7861 ccatcgattt tttgatggca agtttggatt ggacacccaa ggatttggac cgaatcgtgg
     7921 tagctgaagg gccgggtagc tatacaggct tgcgaattgc ggtagcaact gctaagacct
     7981 tagcttacac cctgaacatc gagttggttg gtatgtcgag tctcttggct ctggtgcccc
     8041 accaacaaga aggtttgttt gtccccttga tggatgcgcg tcgcaataat gtttatgcag
     8101 gattttatga aaatgctaaa cctgtcatgg cagaagcgca cctatctttt gaagaggtgc
     8161 tagaaaaagt caagggtact agtcaggtaa cctttgtcgg agaagttggc ccctttgttg
     8221 agcagattca aaaacacttg ccaaggactg attacaaaga aacattgccc aatgcagcta
     8281 atctagctct tttggcctgg gacaaggaag cagactcctt gcatgatttt gtgccgaatt
     8341 acctcaaacg agtcgaggct gaggaaaact ggctcaagaa ccataccgag tctggtgagt
     8401 cctacattaa acgcctatga tagaaatcaa gcgaattcaa caacagcctg acctagctca
     8461 agccatctac gctgttatag cagctgttta cctagtcagt ccttggactc tggagcaaat
     8521 ccaagcagat ctgtcccaag accagacttg gtatgcattg gcttatgatg gggcagaagt
     8581 gattggattt ctagctgtgc aggagaatct ttttgaagca gaagtcctgc aaatcgctgt
     8641 caaaggagcc tatcagggtc agggaattgc gtcagccttg tttgctcaat tgccgacaga
     8701 taaggagatt ttcctcgaag tcagaaagtc aaatcaacga gcgcaagcat tttacaagaa
     8761 agaaaaaatg gcggtcatcg ctgagcgaaa ggcctactac catgacccag tcgaggacgc
     8821 cattatcatg aagagagaaa tagatgaagg atagatatat tttagcattt gagacatcct
     8881 gtgatgagac cagtgtcgcc gtcttgaaaa acgacgatga gctcttgtcc aatgtcattg
     8941 ctagtcaaat tgagagtcac aaacgttttg gtggcgtagt gcccgaagta gccagtcgtc
     9001 accatgtcga ggtcattaca gcctgtatcg aggaggcatt ggcagaagca gggattaccg
     9061 aagaggacgt gacagctgtt gcggttacct acggaccagg cttggtcgga gccttgctag
     9121 ttggtttgtc agctgccaag gcctttgctt gggctcacgg acttccactg attcctgtta
     9181 atcacatggc tgggcacctc atggcagctc agagtgtgga gcctttggag tttcccttgc
     9241 tagccctctt ggtcagcggc ggacacacag agttggttta tgtttcggag gcaggagatt
     9301 ataagattgt tggggaaacc cgtgatgatg cggttggtga ggcttatgat aaggtcggcc
     9361 gtgtcatggg cttgacctat cctgcaggtc gtgagattga cgagctggct catcaggggc
     9421 aggatattta tgatttcccc cgtgccatga ttaaggaaga taatctggag ttctccttct
     9481 caggtttgaa atctgccttt atcaatcttt atcacaatgc cgagcaaaag ggagaaagcc
     9541 tgtctacaga agatttgtgt gcttccttcc aagcagcagt tatggacatt ctcatggcaa
     9601 aaaccaagaa ggctttggag aaatatcctg ttaaaaccct ggttgtggca ggtggtgtgg
     9661 cagccaataa aggtctcaga gaacgcctag cagccgaaat cacagatgtc aaggttatca
     9721 tcccccctct gcgactctgc ggagacaatg caggtatgat tgcctatgcc agcgtcagcg
     9781 agtggaacaa agaaaacttc gcaggctggg acctcaatgc caaaccaagt cttgcctttg
     9841 ataccatgga ataaagagtg gctctttgtc aagtgtagtg ggtaggcgaa aagctacaat
     9901 ctggagagta cgaaattcgt actctctttt ttgatgttca aagtcatcaa aatccgtttt
     9961 ttaaaattgt taaagttccg gaaaccaaag gctttgcgct tgataatctt aatcaaatta
    10021 ttggtcgctt caagtttagc gttggaataa ggcagcttaa gtgcgttgat aatcttatct
    10081 ctatccctta aaaaagtcca aaagaccgtt tgaaaaagcg gatgaaccgt tggcagttct
    10141 tgctcaatca atccaaagaa atggtcggca ttcttctctt gaaaatgaaa gagcaggagt
    10201 tgatagagtt cgtagtgaac ctgtaatccc tcagagtaag aaagcagctt atctcgtact
    10261 tcccgatggg ttaagtgcat tcgaaacgtg ggctgataga atcgtttctg acagagcttg
    10321 aagctatact ggtgtagtaa atcagtccag tggactgatt tagcccgagc ctagaaacga
    10381 aaaagcgagg gttccaaaag cgcttgagcg cccgatactc caaggatttt cggtcaaatt
    10441 ggttcatgat ttggattcgt actcggttca tagctcggct cagatgttgg acaatgtgga
    10501 agcggtcaag aacaatcttc gcctttggaa agagttgctt agcgagccga taataagggc
    10561 tgtacatgtc catggtgatg acctcgacca gctcccgaac ctctctctga tagcgttgga
    10621 aatggtttcg aatcaccgca tgagttcgcc cgtctaaaat tgcgaggatg gatttggact
    10681 caaaatcttg ggcaatgaag ctcattttgc tctttttgaa gctatactca tcccaactca
    10741 taacttttgg caacttggtc caatcggttt caaacttaaa ttccctcagt tttcggatga
    10801 cggtggaagt tgagaccgcc aatctgtggg caatctcagt catagactgc ttttcaagga
    10861 ggagctgagc gattttttgt ctcaccatgt tggaaatctg gcaatttttc ttgacaatgg
    10921 atgtttgaga aacgaccacc ttaaggcaat tcttgcactg aaagcggcgc tttttgagat
    10981 gcagtaccgt gggtaaaccc tgacagtcga gaagcggaat tttagaggct ttctggaagt
    11041 cgtatttgat catcttccct tgacaatgag gacaaggagg agcgggggaa tccaactttg
    11101 cctgaacgac tagatgggtt tggtatttca gaacagacaa gatttttata tttttgtctt
    11161 ccaatccgag caaatctgtg gtattcttaa gttgttccat atgaaccctt tctaatgagt
    11221 tggttagacg cttttcatta taggtcatat ggggcttttt ttctacaaga aacgacccta
    11281 taattcctgg ggtgggatta cccactacag aaattataga gccaaagcat tccaaagtct
    11341 tgtctgactc tggaatgttt tctgttcaca gttgttttgt aactgcctaa taagtaaccg
    11401 cgctataacg aggtatctac cgagattgtc aattctccag tatactgtta taaaaaacaa
    11461 aactggagga tttttttatg tccccccatc gtcccatcga ctgttccgta gctgcccaat
    11521 aacggagtat agtcggctga aacaagaata ggacaaaagt gcctcaagaa aagcatcgta
    11581 atttgacaat attattctga gatgtttttg atgtaagccc atattttctc aatgggatta
    11641 tactcgggtg aataggtagg aagtggtaac agtctatgcc ctgctcctta cacatgttca
    11701 ttctgtgaaa ccttgcatgg tccataatga taagggatgg tgtatctaaa gtaggtagta
    11761 agaatttttg gaagcaagct tcgaaaaagt cactcgtcat cgtatcttta taggtcatcg
    11821 gagccatagt atattgaaac aaaaaagggt attagtactt ctataacagt atcgcaatct
    11881 ctggtgtgcg ttgtctcgat cttaattcaa ataattatat cttcttccag agagactaac
    11941 tgcctgctca aggatcaatc atattcgaga taaaaatagg tctcaacccc tgtctcataa
    12001 atataaatag gagtcaggta gcttaagtga ttcaattctt taaggaaccg atttactttt
    12061 tctgggtctt gttcgcagta ggtacggctc ttttttagac tatatcccat agcctttaga
    12121 gcgtaatgaa tagttgttgg aggacagttg aattcagcag ctatttcagt caaataagca
    12181 tcgggatgag tttcaatata gatctttaat ttatctctat caactttttc aattaatagt
    12241 ggaagttttc ttgaagttag tgtattgaaa cgtttttata cagtgctaaa atttgaagtg
    12301 tagtgcagat gtatttgtaa tagtattata gcaattcttt ggagaaggtc gagacaagag
    12361 aaaataggta tctttgagat ataagcatga tttactataa aattattgag ttattcataa
    12421 aaatttctct atcaaatatc ataatgcgtc gtttaaggag atggttacaa tgcaatatag
    12481 ttgtggaaaa ataaatatta atatccctga tggatatgga gacattaagg atatagtgtt
    12541 ttcggctcat attatagtta ggtataataa tggacattgt ggaggtatag atccgcatat
    12601 aattggactt tgtaaaaagc agatcagaag gatgtctcta tatcctattt tgataatcgt
    12661 atctagagat tcaaaggtta ttgatgatta taaaaattta gatattgcct atgttgattg
    12721 tactcaatgt tcaaataatt ttgaaactgc cttacacgtt aaaaatattt taaaattatt
    12781 aaaaatccaa cttatacact gtcatggcta ctcaactaat tattttttat atatgttaaa
    12841 aaaacttgac aagaatggat ttggaaaggt taagacagtg ataacatgcc atggatgggt
    12901 tgaatataac ttaaaaaaga aattcttgac ttattttgat ttttggacat attctatggg
    12961 agatgctttt atttgtgtat ctgaaactat gaaaaaaaga ttggagagta taataaaaaa
    13021 taagaagata gttgcaataa ataacggaat taatgtatca aatagcgatt tagatgtagt
    13081 aggtgttcaa gactttaaaa aagaattttg tattccaaat aacaaaaaaa tcatttgtta
    13141 tgttggaagg ttggatccag aaaaaaggcc ggatagattc cttgaatttg cagaaaaatt
    13201 atttttagtc agagaagatg tgatttttat tatggctgga aatggtagta tgtgggctgc
    13261 tttgaaagaa aaaatttgcc atttgaaatg tagagataat ttcaggttac ttggtgaaat
    13321 ctatccagct actatagttt accaaatatc ggatttattg tatattcctt atgatacaga
    13381 aggaatacct atgtgtgttt tagagtcaat gtcacaagga actccggttt tagctagtaa
    13441 tgttggcggg ttaagtgaaa ttattgaaca tagggttgat ggatttttat ttgagaagga
    13501 agatgttgag ggagtgtgtg cttgtgctaa ttttttactc aatgattctg agtatttgaa
    13561 atatataggt gagaatagta aatcaaaaat aagaaaacat ttttctgtgc aaaaaatgtt
    13621 tgtagaaacc atgagagtat atgatgaatt attagagaag agtagtcatg gataggaata
    13681 tagatcaaga attagtaagt attataatac caacacataa taggtatgaa tctctgatta
    13741 gagctgtgaa aagttgttta catcaaagtt ataaaaatat cgaagttata attattgatg
    13801 ataattatag taatgtaaat ttaagaaata aaattatcca tcaatttggc tataccaatc
    13861 atagaattaa gttaatttta agtaatgaag atttaggtgc aactaatgcc agaaacatag
    13921 gtataaaaaa ttctagaggt aagtatatat catttttaga cgatgatgat gaatatatgc
    13981 cagatcgaat tttaaagttg atggcttgtt ttaaaaagag tagaatgaag aatttagctt
    14041 tagtttatag ttatggaata ataatttatc caaatggtac acgagaagag gagaagaccg
    14101 attttgttgg aaatcccttg tttgttcaaa tggttcacaa tatagcaggt acgtcatttt
    14161 ggttgtgtaa aaaagaggtg ctagaattaa ttaatggttt tgagaaaata gattcacatc
    14221 aggacggtgt tgttttatta aaactacttg ctcaaggata ccaaattgat atagtgcgag
    14281 aattcttggt gaattactac gctcacagta aagaaaacgg tatcactgga gtgacacaaa
    14341 aaacaattaa tgcagatgaa gaatattata attactgtag gaaatatttt aatttattga
    14401 gtttcaacga gagaatattg gttacaaaga aatattattc tttaaacata aagcggttac
    14461 tattaatagg agacaaatgc aaggctttaa aagtaatcaa gaaggcaaga gaagaaaaaa
    14521 tttttaacga atttcttttt ttgaaataca tgttattata ttattttggt tttttctatt
    14581 gtatatatga caactatgtt caattaaaat ttagaaagtg agaaa
//
LOCUS       DBEJAU010000048        14440 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC323 isolate 683620
            SAMN38261939-rid24807223.denovo.048, whole genome shotgun sequence.
ACCESSION   DBEJAU010000048 DBEJAU010000000
VERSION     DBEJAU010000048.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261939
            Sequence Read Archive: SRR26833919
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 14440)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14440)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576303.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576303.1
            Genome Coverage       :: 154x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/19/2025 01:05:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,121
            CDSs (total)                      :: 2,078
            Genes (coding)                    :: 1,943
            CDSs (with protein)               :: 1,943
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 36
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 72 of 135
            Pseudo Genes (incomplete)         :: 63 of 135
            Pseudo Genes (internal stop)      :: 51 of 135
            Pseudo Genes (multiple problems)  :: 46 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14440
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261939-rid24807223.denovo.048"
                     /strain="GPSC323"
                     /isolate="683620"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            <1..4173
                     /locus_tag="ACL29Z_001679"
     CDS             <1..4173
                     /locus_tag="ACL29Z_001679"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000639857.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tail fiber domain-containing protein"
                     /protein_id="HGR0069952.1"
                     /translation="TTNEWLFNFNQEGTIWIWMPKFEISDVDTSYSEAPEDIEGQIST
                     VESNFKQRADSLEAGVSRLTEGLRTKADISALNVTAENIRQSVKSLETDTQNKLNQKL
                     SQAEFEVRAGSIRQEILNVTKDKASKSELTQTAEELSSKIASVQVGGINLLRNTASLL
                     IGDRSKGCWMSASGGNGRAISVEVLDPPKKMIKNMIRVIENTNGGNKDLTQLVRLRIG
                     EKYTISCYARIASDSPNANVNLLFRSWANNTDLNRKFQKSISHKNWQKYSFTFTADAI
                     ENSIQFGQSGAGIIEICAPKIESGTLATDYSEAPEDIEGQISTVESTFKQRANSLEAG
                     VNRLTEGLRTKADISSLNVTAENIRQSVKSLETDTQNKLNQKLSQAEFEVRAGSIRQE
                     ILNATKDKADKTLVVAEAGKLREEFSKMKVGGRNLWIKSKTVGAVIEKLPENHVTGQK
                     ECYRLENNSTLTFNLEPDFSSRLYQKVTFSAWIKYENVVQGRNFWNVFNCFKHYLFRK
                     NSETGVQSGPDYATLGMYKGSADWKYITFTYDYSEKTNFDQLKTSLRFNLEGATSGTA
                     WVTGIKVEIGSVATDWAPAPEDGENELLVAKTEFKRTADGLSTKMAAVESYVGQDGQR
                     QEALQRYTREESARQATAVRELVNRDFVGKATYQEDVKGINQRIEAVKTSANKDIASQ
                     IASYRQSVDGKFTDISSQITTYKQDVGGQISGLSNRLTSSEQGTTTQISNLSNRINSN
                     KQGADNQISNLKTQVATNKDNAERQMGRISDQVSANKANADSQFANVTNQLARKVETT
                     DFQRVKETSKLYERILGNTENGIADKVARMALTNQLFQVEVGKYSVSGPNLIKNSDFK
                     NATNEWGSTQNLGRLVKHSFYHNGQKDLMRLSNATKNENFLYSHRFNLERNTDYVLNF
                     RGFNNSALASYDVYILGRRAGESDGFTIVKKVVSSKKLSTSRCEDVSVTFNSGEMDNA
                     YIRFDNNGSSSGTADLYITEVDLYKGYKPRTWQPHPEDVVADANKKLEATQTKMTLLT
                     GSWAVQNINSAGDIISGINLGANGHNRFVGKLTHITGETLIDRAVIKSAMVDKLKTAN
                     FEAGSVTTTILDAEAVTAEKLKVDNALIKKLTATDAFIYELISKRIFSTKVESVISSS
                     TFLEAYQGRIGGFTLGQFDQGGGRWISGVNQFSVGMGNGAGHGVRTAFWANWGNNWNY
                     AGPKAWNVNTDGKMYCRNEVGFYDQVDFSNSSRANFYGNTTFSRSPVFSNGIELGSKD
                     VLGDGWNPKGGRNAVVWWNQVGSGSVKYWMEQKSDRRLKENITDTAVKALDKINRLRM
                     VAFDFIESKKHEEIGLIAQEAETIVPRIVSRDPENPDGYLHIDYTALVPYLIKAIQEL
                     NQKIEKMEKTIA"
     gene            4170..4286
                     /locus_tag="ACL29Z_001680"
     CDS             4170..4286
                     /locus_tag="ACL29Z_001680"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001063632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrodipicolinate reductase"
                     /protein_id="HGR0069953.1"
                     /translation="MNNNMLTNIALKAIQELALENRKRTHRLENLENEHRTA"
     gene            4267..4470
                     /locus_tag="ACL29Z_001681"
     CDS             4267..4470
                     /locus_tag="ACL29Z_001681"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001091107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0069954.1"
                     /translation="MNTEQLNQALRMTISEISITSTNSMIESNILSIQLDEQREENQR
                     LQARVDELEALLDEQTKPADKGE"
     gene            4473..4823
                     /locus_tag="ACL29Z_001682"
     CDS             4473..4823
                     /locus_tag="ACL29Z_001682"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0069955.1"
                     /translation="MAETIQNTDNLLDLTKITEPFDLASALRYMKENGEFIRCKNVSD
                     DFYMYRDVQKRPVIVNGRRQLKDVETVWAFNQWGGTIATINVAVLLNHEFYIMKFDAE
                     GNPDWTDPTGEPKE"
     gene            4833..5249
                     /locus_tag="ACL29Z_001683"
     CDS             4833..5249
                     /locus_tag="ACL29Z_001683"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003038967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage holin family protein"
                     /protein_id="HGR0069956.1"
                     /translation="MQIEFFNFLRSVVQTEDGLVLYALALIVSMEIIDFVTGTIAAII
                     NPDIEYKSKIGINGLLRKISGVLLLMILIPASVLLPEKTGFAFLYSIYLGYIAFTFQS
                     LIENYRKLKGNVTLFQPIVKVFQRLLEKDDDTKKGE"
     gene            5253..5585
                     /locus_tag="ACL29Z_001684"
     CDS             5253..5585
                     /locus_tag="ACL29Z_001684"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001186229.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0140911 - pore-forming activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phage holin"
                     /protein_id="HGR0069957.1"
                     /translation="MQQITEIITNGAISILVILAGVVVRAVKDYLVQKGGEKTIKIVE
                     ILAKNAVNAVEQVASETGFKGDEKLEQARAKVRAELTKYNISMTDKDLDTFVESAVKQ
                     MNDAWKGR"
     gene            5589..6545
                     /locus_tag="ACL29Z_001685"
     CDS             5589..6545
                     /locus_tag="ACL29Z_001685"
                     /EC_number="3.5.1.28"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000405235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008745 - N-acetylmuramoyl-L-alanine
                     amidase activity [Evidence IEA];
                     GO_process: GO:0009253 - peptidoglycan catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="HGR0069958.1"
                     /translation="MDIDRNRLRTGLPQVGVQPYRQVHAHSTGNRNSTVQNEADYHWR
                     KDPELGFFSHVVGNGRIMQVGPVNNGSWDVGGGWNTESYAAVELIESHSTKEEFMMDY
                     RLYIELLRNLADEAGLPKTLDTDDLAGIKTHEYCTNNQPNNHSDHVDPYPYLASWGIS
                     REQFKQDIENGLSAATGWQKNGTGYWYVHSDGSYPKDKFEKINGTWYYFDGSGYMLSD
                     RWRKHTDGNWYYFDQSGEMATGWKKIAEKWYYFDVEGAMKTGWVKYKDTWYYLDAKEG
                     AMVSNGFIQSADGTGWYYLKPDGTLADKPDFTVEPEGLITVK"
     gene            complement(6683..6862)
                     /locus_tag="ACL29Z_001686"
     CDS             complement(6683..6862)
                     /locus_tag="ACL29Z_001686"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001209433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0069959.1"
                     /translation="MREVIQELLDSSMSTSAISQGAGVPWTTVSDLRKGKTSMDKMAL
                     LTAEKLYEFATTDKQ"
     gene            complement(7004..7153)
                     /locus_tag="ACL29Z_001687"
     CDS             complement(7004..7153)
                     /locus_tag="ACL29Z_001687"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0069960.1"
                     /translation="MNKEDWLRLLEKAIDNIPETVTAIASLVTAITVARQNKKRKPKS
                     RQRKR"
     gene            7435..7902
                     /gene="tadA"
                     /locus_tag="ACL29Z_001688"
     CDS             7435..7902
                     /gene="tadA"
                     /locus_tag="ACL29Z_001688"
                     /EC_number="3.5.4.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008251 - tRNA-specific adenosine
                     deaminase activity [Evidence IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_process: GO:0002100 - tRNA wobble adenosine to inosine
                     editing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA adenosine(34) deaminase TadA"
                     /protein_id="HGR0069961.1"
                     /translation="MYYTLEEKEVFMREALREAEIALEHDEIPIGCVIVKDGEIIGRG
                     HNAREELQRAVMHAEIMAIEDANLSEESWRLLDCTLFVTIEPCVMCSGAIGLARIPNV
                     VYGAKNQKFGAAGSLYDILTDERLNHRVEVETGILEDECAAIMQDFFRNRRKK"
     gene            7935..8028
                     /gene="ffs"
                     /locus_tag="ACL29Z_001689"
     ncRNA           7935..8028
                     /ncRNA_class="SRP_RNA"
                     /gene="ffs"
                     /locus_tag="ACL29Z_001689"
                     /product="signal recognition particle sRNA small type"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00169"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00169"
     gene            8088..8531
                     /locus_tag="ACL29Z_001690"
     CDS             8088..8531
                     /locus_tag="ACL29Z_001690"
                     /EC_number="3.6.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000701981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dUTP diphosphatase"
                     /protein_id="HGR0069962.1"
                     /translation="MKIRGFELVSSFTDENLLPKRETAHAAGYDLKVAVRTVVAPGEI
                     VLVPTGVKAYMQPTEVLYLYDRSSNPRKKGLVLINSVGVIDGDYYGNPGNEGHIFAQM
                     KNITDQEVVLEVGERIVQAVFATFLIADGDAAGGVRTGGFGSTGH"
     gene            8533..9048
                     /locus_tag="ACL29Z_001691"
     CDS             8533..9048
                     /locus_tag="ACL29Z_001691"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000691237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HGR0069963.1"
                     /translation="MKIIFVRHGEPDYRELEERSYIGFGIDLAPLSEMGRQQVQKLSK
                     NPLLSSAEIIVSSAVTRALETASYVVCATGLPLRVEPLLHEWQVYKTGIENFETARRL
                     FLENKGELLPNSPIQYETATEMKSRFLECMSKYREHQTVVVVAHRMLMRQFVPNEKID
                     FCQVIECELEI"
     gene            9062..10423
                     /gene="radA"
                     /locus_tag="ACL29Z_001692"
     CDS             9062..10423
                     /gene="radA"
                     /locus_tag="ACL29Z_001692"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016893792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003684 - damaged DNA binding [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RadA"
                     /protein_id="HGR0069964.1"
                     /translation="MAKKKATFVCQNCGYNSPKYLGRCPNCVSWSSFVEEVEVAEVKN
                     ARVSLTGEKTKPMKLAEVTSINVNRTKTEMEEFNRVLGGGVVPGSLVLIGGDPGIGKS
                     TLLLQVSTQLSQVGTVLYVSGEESAQQIKLRAERLGDIDSEFYLYAETNMQSVRAEVE
                     RIQPDFLIIDSIQTIMSPEISGVQGSVSQVREVTAELMQLAKTNNIAIFIVGHVTKEG
                     TLAGPRMLEHMVDTVLYFEGERHHTFRILRAVKNRFGSTNEIGIFEMQSGGLVEVLNP
                     SQVFLEERLDGATGSSIVVTMEGTRPILAEVQALVTPTMFGNAKRTTTGLDFNRASLI
                     MAVLEKRAGLLLQNQDAYLKSAGGVKLDEPAIDLAVAVAIASSYKDKPTNPQECFVGE
                     LGLTGEIRRVNRIEQRINEAAKLGFTKIYVPQNSLTGITLPKEIQVIGVTTIQEVLKK
                     VFA"
     gene            10496..10993
                     /locus_tag="ACL29Z_001693"
     CDS             10496..10993
                     /locus_tag="ACL29Z_001693"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007285146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-class carbonic anhydrase"
                     /protein_id="HGR0069965.1"
                     /translation="MSYFEQFMQANQAYVALHGQLNLPLKPKTRVAIVTCMDSRLHVA
                     QALGLALGDAHILRNAGGRVTEDMIRSLVISQQQMGTREIVVLHHTDCGAQTFENEPF
                     QEYLKEELGVDVSDQDFLPFQDIEESVREDMQLLIESPLIPDDVIISGAIYNVDTGSM
                     TVVEL"
     gene            11018..11801
                     /locus_tag="ACL29Z_001694"
                     /pseudo
     CDS             11018..11801
                     /locus_tag="ACL29Z_001694"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000749763.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0008233 - peptidase activity [Evidence
                     IEA];
                     GO_function: GO:0070007 - glutamic-type endopeptidase
                     activity [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="PrsW family glutamic-type intramembrane
                     protease"
     gene            11946..12914
                     /locus_tag="ACL29Z_001695"
     CDS             11946..12914
                     /locus_tag="ACL29Z_001695"
                     /EC_number="2.7.6.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006149122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004749 - ribose phosphate diphosphokinase
                     activity [Evidence IEA];
                     GO_process: GO:0009156 - ribonucleoside monophosphate
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-phosphate diphosphokinase"
                     /protein_id="HGR0069966.1"
                     /translation="MSFSDLKLFALSSNKELAERVAQEIGIELGKSSVRQFSDGEIQV
                     NIEESIRGKHVFILQSTSSPVNDNLLEILIMVDALKRASAESVNVVMPYYGYARQDRK
                     ARAREPITSKLVANMLEVAGVDRLLTIDLHAAQIQGFFDIPVDHLMGAPLIADYFERR
                     GMVGSDYVVVSPDHGGVTRARKLAEFLKTSIAIIDKRRSVDKMNTSEVMNIIGKVEGK
                     TCILIDDMIDTAGTICHAADALAEAGAVEVYASCTHPVLSGPATDNIQKSAIKKLVVL
                     DTIYLPEERLIDKIEQISIAHLLGDAIVRIHEKRPLSPLFDIEKKI"
     gene            complement(13048..13329)
                     /locus_tag="ACL29Z_001696"
                     /pseudo
     CDS             complement(13048..13329)
                     /locus_tag="ACL29Z_001696"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_086558202.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
     gene            complement(13456..14363)
                     /locus_tag="ACL29Z_001697"
                     /pseudo
     CDS             complement(13456..14363)
                     /locus_tag="ACL29Z_001697"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000603324.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="Rpn family recombination-promoting
                     nuclease/putative transposase"
BASE COUNT         4301 a         2601 c         3393 g         4145 t
ORIGIN      
        1 accacaaatg aatggttgtt caatttcaac caggaaggaa ccatttggat ttggatgccg
       61 aagtttgaaa taagcgatgt agatacttct tattcagaag ctcctgaaga tatagaaggt
      121 cagatttcaa cagttgaatc caactttaaa cagcgtgctg attcactcga agctggtgta
      181 agccgtctga ctgaagggct tagaactaaa gccgatatca gcgcactcaa cgtgactgct
      241 gagaatatta ggcaatctgt gaagagtctt gagacagaca cgcagaacaa actaaatcag
      301 aagttgagtc aggctgaatt tgaggtgcga gctggctcta ttcgtcagga aatcctgaac
      361 gtaaccaagg ataaagccag caagtcagaa cttacgcaga cagctgagga gctctctagt
      421 aagatagcga gtgtgcaggt cggaggaatc aacctcttgc gtaatactgc gagtttgttg
      481 attggcgatc gttcaaaagg atgttggatg agtgcaagcg gaggaaatgg gcgagcgatt
      541 agcgtagaag ttttggatcc tcccaaaaaa atgataaaaa acatgattcg tgttattgaa
      601 aatacgaatg gtggaaataa agatttaact caacttgtta gattgcgaat tggtgaaaag
      661 tacacgattt cttgttatgc aaggattgct agcgatagcc caaatgcaaa cgtgaacttg
      721 ctatttcgtt cgtgggcaaa taataccgat ttaaatcgca aatttcagaa atccatctct
      781 cataaaaatt ggcaaaaata ttcatttaca tttactgctg atgcaattga aaattcaatt
      841 caatttggac aatctggcgc aggaattatc gaaatatgcg ctccgaaaat cgaatcagga
      901 acgttagcga ctgattacag cgaagctcct gaagatatag aaggtcagat ttcaacagtt
      961 gaatcgacct ttaaacaacg agccaactcg ctcgaagctg gtgtgaatcg tctgactgaa
     1021 ggccttagaa ctaaagccga tatcagctca ctcaatgtga ctgctgaaaa tatccggcaa
     1081 tctgtgaaga gtcttgagac agacacgcag aacaagctaa atcagaagtt gagtcaggct
     1141 gaatttgagg tgcgagccgg ctctatccgt caggaaatcc tgaacgcaac caaggataag
     1201 gcagataaga ctcttgtcgt ggctgaagcc gggaaattgc gtgaagaatt ttcaaaaatg
     1261 aaggtgggag gccggaatct atggataaaa tccaagacgg ttggagctgt aattgaaaaa
     1321 ttacctgaaa accacgtcac aggtcaaaaa gaatgctata ggctagagaa caactctact
     1381 ttaacgttca accttgaacc agatttcagc tcaaggttgt accaaaaagt tacttttagc
     1441 gcttggatca agtacgaaaa tgtagtccaa ggtcgaaatt tttggaatgt atttaattgc
     1501 ttcaaacatt atctttttag aaaaaatagt gagaccggag tacagagtgg tccagattat
     1561 gctacgcttg gtatgtataa aggttcggca gattggaaat atattacatt cacttatgac
     1621 tactctgaaa aaacaaattt tgatcaattg aagacatcat tgcgattcaa tcttgaaggt
     1681 gctacaagcg gtacagcttg ggtaacagga atcaaggttg aaatcggtag tgtggcgacg
     1741 gactgggcac cagcaccaga agacggagaa aatgagcttt tagtcgctaa aaccgagttc
     1801 aagaggacag ctgatggcct atctactaag atggcagcag ttgagagcta tgttggtcaa
     1861 gacggtcagc gacaggaagc cctacagcgc tatactcgtg aggagagcgc gagacaagcg
     1921 acagcagtcc gtgagctggt caatcgtgat ttcgttggta aggctactta tcaagaagat
     1981 gttaagggta tcaatcaaag gattgaagct gttaaaacta gtgcgaataa agacatcgct
     2041 agtcaaatcg ctagctatcg tcaatctgta gatggtaagt tcacggatat ttcaagtcag
     2101 ataactactt ataagcaaga tgtgggcggt caaatcagtg gcctttcaaa tagacttaca
     2161 agcagtgagc aaggaaccac tactcagatt tcaaatcttt caaatcggat aaacagtaat
     2221 aaacaaggcg cagataatca gatttcaaat ttaaagactc aggtcgctac aaacaaggat
     2281 aatgctgaac gacaaatggg tagaatatct gatcaggttt ctgcaaacaa agcgaatgct
     2341 gatagtcaat ttgcgaatgt gaccaatcaa ctagcacgaa aagtagagac tactgacttc
     2401 cagcgtgtta aggaaaccag taaactttac gagcggattt tgggcaatac tgaaaatgga
     2461 attgcggata aggttgctcg catggctctg accaatcaac tgtttcaggt tgaggttggg
     2521 aaatatagtg taagcggccc taacctcatt aagaatagtg attttaaaaa tgctacgaat
     2581 gaatggggct caactcaaaa tttaggaaga ttggttaagc atagctttta tcacaacggg
     2641 cagaaagacc ttatgcgttt aagtaatgca actaaaaacg aaaacttttt gtatagtcac
     2701 cgttttaatc ttgaacgaaa tactgactat gtactgaatt ttagaggatt taacaacagt
     2761 gctctcgcaa gctatgatgt ttatattttg ggacgaagag caggcgagag cgatggattc
     2821 acaatcgtta agaaagttgt tagcagcaag aaactatcta cctctagatg cgaagatgtc
     2881 tcagtaactt ttaattccgg agaaatggat aatgcttaca ttcgttttga taacaatggc
     2941 tcatcatcag gaacagctga tttgtatatt acagaagttg acttgtacaa aggttataaa
     3001 cctagaacat ggcaaccaca tccagaagat gtggtcgcag atgcgaataa gaagcttgaa
     3061 gccacgcaaa caaaaatgac tctactaact ggctcatggg cagttcaaaa catcaactcg
     3121 gctggagata tcatctctgg aatcaatctt ggcgccaatg gacataaccg ctttgttggg
     3181 aaattgaccc acatcactgg agagaccttg attgacagag cagtcatcaa gtctgccatg
     3241 gttgataagc tcaaaacggc caattttgaa gctggttcgg tcacgactac gatattagac
     3301 gctgaagcgg taactgctga gaagttgaaa gttgacaatg cgcttattaa aaaattaact
     3361 gcaactgatg cttttattta cgaactgata tctaaacgta tcttctctac taaggttgag
     3421 tccgtcattt ctagttcaac cttcctagaa gcctatcaag gccgaatcgg tggattcaca
     3481 cttggtcaat ttgaccaggg tggcggtcgc tggatttcag gtgtcaatca gttctctgtt
     3541 ggtatgggga atggtgccgg gcatggagtc cggacagcct tctgggcgaa ctggggaaat
     3601 aattggaact atgccggacc taaagcatgg aacgtcaata ctgatgggaa aatgtactgt
     3661 aggaatgaag tcggttttta tgatcaagtg gatttttcga attcatcgag agcaaacttc
     3721 tatgggaata ctactttttc tcgttctcct gtgttttcaa atggtatcga acttggaagt
     3781 aaagatgtgc ttggtgatgg ttggaatccc aaaggcggaa ggaatgcggt tgtttggtgg
     3841 aatcaggtcg gtagcggtag cgtgaagtat tggatggaac aaaaatcaga cagacgctta
     3901 aaagagaaca tcacagatac agctgtgaaa gccttggata aaatcaacag attaagaatg
     3961 gttgcatttg atttcatcga aagtaagaaa catgaggaga ttggtctaat agctcaagag
     4021 gctgaaacca tcgttccaag aattgtctca cgagatcctg agaatccaga tggctatcta
     4081 catatcgact ataccgcttt agttccttac ttaatcaagg ctattcaaga attaaatcaa
     4141 aaaatagaaa aaatggagaa aacaatagca tgaataacaa catgttgacc aatatcgcac
     4201 ttaaagcaat tcaggagctt gctcttgaaa atagaaaacg aacacacaga ttggagaact
     4261 tagaaaatga acacagaaca gcttaaccaa gccttacgaa tgacaattag tgaaatatca
     4321 ataacttcaa caaattcgat gattgaaagt aatatcttga gtattcagtt ggatgagcaa
     4381 agggaagaga atcaaagact tcaagcacga gtggatgagc tggaagctct gcttgatgaa
     4441 caaactaaac cagcagacaa aggagaatag acatggcaga aacaattcaa aacacagata
     4501 acttgctaga ccttacaaaa atcacagaac catttgatct tgcgagcgct ttgcgctata
     4561 tgaaagaaaa tggagagttc attcgttgca agaatgtaag cgatgacttc tatatgtatc
     4621 gtgatgttca aaaacgtcct gtgatcgtaa atggccgtcg ccaactcaag gatgttgaaa
     4681 ccgtttgggc gttcaaccag tggggtggta caatcgcaac aatcaacgtc gccgttctgt
     4741 tgaatcatga attctatatc atgaaatttg atgcagaggg caatcctgac tggacggatc
     4801 caacgggaga acctaaagaa taggagatgt gtatgcaaat tgaatttttc aattttctaa
     4861 gaagtgtcgt acagactgaa gatggtttgg tcttgtacgc tctagcactg attgtctcaa
     4921 tggaaatcat tgattttgtg acagggacga ttgcggcgat tatcaatcct gatatcgagt
     4981 acaagagcaa aatcggcatt aacgggctcc ttcgtaagat ttcaggggtt ctcttactga
     5041 tgatcctcat tccggcgtcc gttttgttgc ctgaaaagac aggttttgca ttcttgtact
     5101 caatctatct cgggtacatc gcatttactt ttcaatcact cattgaaaat taccgcaaat
     5161 taaaaggaaa tgttactctt tttcagccga ttgtaaaagt atttcagcga ttacttgaaa
     5221 aagatgatga tacgaaaaaa ggagaataac aaatgcaaca aattactgaa atcattacta
     5281 atggagcaat cagcatccta gtcattttag caggggtggt agttagggca gtcaaggact
     5341 acctggttca aaaaggtgga gaaaagacca tcaaaatcgt tgaaatcttg gccaaaaacg
     5401 cagttaatgc cgtggagcag gttgcctcag agactggctt taaaggcgat gaaaagctgg
     5461 agcaggctcg tgctaaagtc cgtgctgagc ttacaaaata caatattagt atgactgaca
     5521 aagacttaga caccttcgta gagtcagcag tgaagcagat gaatgacgca tggaaaggac
     5581 gatagggaat ggatatcgat agaaacagac tacgtacagg cttgccacag gttggggtgc
     5641 agccttatcg acaagtacat gctcactcaa caggtaaccg caactcaacc gtacagaatg
     5701 aagcggatta tcactggcgg aaagacccag aattaggttt tttctcgcac gttgttggga
     5761 acggtcgcat catgcaggta ggacctgtga acaacggaag ttgggatgtt gggggcggtt
     5821 ggaatactga gagttacgca gcggttgaac tgattgaaag ccattcaact aaagaagagt
     5881 tcatgatgga ctaccgcctt tatatcgaac tcttacgcaa tctagcagat gaagcaggtt
     5941 tgccgaaaac gcttgataca gacgacttgg caggtatcaa gacgcatgaa tactgtacca
     6001 ataaccaacc aaacaaccac tcagaccatg tggatccata tccatatctt gcaagttggg
     6061 gcattagccg tgagcagttt aagcaagaca tcgaaaacgg cttgagcgct gcaacaggct
     6121 ggcagaaaaa tggcactggc tactggtacg tacactcaga cggctcttat ccaaaagata
     6181 agtttgagaa aatcaacggt acctggtatt atttcgatgg ctcaggctat atgctttcag
     6241 accgctggag gaagcacaca gacggtaatt ggtactactt tgaccaatca ggcgaaatgg
     6301 ccacaggctg gaagaaaatc gctgagaagt ggtactattt tgatgtagaa ggtgccatga
     6361 agacaggctg ggtcaagtac aaggacactt ggtactactt agacgctaaa gaaggcgcca
     6421 tggtatcaaa tggctttatc cagtcagcgg acggaacagg ctggtactac ctcaaaccag
     6481 acggaacact ggcagataag ccagacttca cagtagagcc tgaaggcttg attacagtaa
     6541 aatagataga aaggaaactt tctaaattgt tctttcaccg caggctcagg cttgcggttt
     6601 tttatttgct ctgattcttc aaaaaaacgt ttacatgaaa aatagggagg tgttttgtta
     6661 aaaataaaaa cagtgatcga aatcactgct tatcagttgt agcaaattca taaagttttt
     6721 ctgctgtgag aagtgccatt ttgtccatgc ttgtttttcc ttttctgagg tcagaaacag
     6781 tagtccatgg aactccagca ccttgggaaa tagcagatgt agacatcgaa ctgtctaaca
     6841 attcttgaat aacttctctc atcttatttg tcctttttat tttttagata aatatataca
     6901 ttgattgcaa ttataaaaat agctattgca ctaaccattg catttcctct ttccatttga
     6961 taaaatagag gtgtaagggg ctttcgcccc aacctcttag cgtttacctt tttctttgac
     7021 gggatttcgg tttacgcttt ttgttttgcc ttgcgaccgt tattgcggtc actagacttg
     7081 cgatagcagt taccgtttca ggaatattgt ctattgcctt ttcaagtaac ctgagccaat
     7141 cttctttgtt caacttcatc accccctttc cttatcttga ttatattata tcacggtaca
     7201 ccgagaaagt caagcgtttt gatgaagttt ttttaatttt ttcaaaaaaa aaatagacct
     7261 tgtccagagg tcggggagtt ggaggggaca ccctccaaga gtgttgattt aataagattt
     7321 tattttacct ttttcataat aatctcccta tagagtcacc gcattcggtg gctttttttg
     7381 tgttgggatt catgatataa taataaaatc gataagtagg aaaagagaaa agagatgtat
     7441 tatacgcttg aagaaaaaga agtctttatg agggaggctt tgagagaggc tgagattgct
     7501 cttgaacacg atgaaattcc aattggttgt gtgattgtca aagatgggga aatcattggt
     7561 cgtgggcata atgcgcgtga ggaattacag cgagcggtta tgcatgcgga aattatggct
     7621 atagaggatg cgaacttgag tgaggagagc tggcgcttgc tggattgcac actttttgtg
     7681 accattgaac cttgtgtcat gtgtagtggg gcgattgggc ttgcccgtat tccaaatgtg
     7741 gtctatgggg ctaaaaacca gaaatttggc gctgctggaa gtttgtacga tatcttgaca
     7801 gatgagcgtc ttaaccatcg tgtagaggtt gaaacgggaa ttttggaaga tgaatgtgca
     7861 gctatcatgc aggacttttt tagaaataga cggaaaaaat aattttgctt ttaaaatgaa
     7921 taggaatgtg atataataaa tagtggagca acagttctgc gtgaagcggg tcaggggagg
     7981 aatccagcag ccctaagcga tttgaattgt gtgctctttt ttcgtgcttt ttccgaataa
     8041 ataagataga ataatctaga ataaatgata atagaaaaga gaaaattatg aaaattcgtg
     8101 gttttgaatt ggtttcgagt tttacagatg aaaatttatt gcccaagcgt gagacagcgc
     8161 atgcggctgg ttacgactta aaggttgctg tgcgtacagt tgttgcgcca ggagagattg
     8221 tcttggttcc gacaggggtt aaggcttata tgcagccgac tgaggttctc tacctctatg
     8281 atcgttcttc aaatcctcgt aagaagggct tggttttaat taactcagtt ggggtcattg
     8341 atggggatta ttatggaaat cctggaaatg aagggcatat ttttgcgcag atgaagaata
     8401 tcacagacca agaggttgtt cttgaagttg gggaacgtat tgtccaggct gtttttgcta
     8461 ctttcttaat tgcagatgga gatgcagctg gtggcgttcg aactggtgga tttggatcga
     8521 cagggcacta gaatgaagat tatctttgta cgtcatgggg agccagatta ccgtgagtta
     8581 gaggagcgtt cttatatagg atttgggata gatttggcac ccttgtctga gatgggacgg
     8641 cagcaagtcc agaaattgag caaaaatcct ttactctcgt cagctgaaat aatcgtatct
     8701 tctgcagtca caagagcttt agaaacggct tcgtatgtgg tctgtgctac gggtcttcct
     8761 ttaagagtag agcctttatt acatgaatgg caggtctata aaacaggaat agaaaacttt
     8821 gaaacagcta gaagactgtt tttagaaaac aagggggagt tgcttcctaa tagtcctatt
     8881 caatatgaga cagctacgga aatgaagtct cggtttctag aatgtatgtc taagtatcga
     8941 gaacatcaga ctgtggtagt tgttgctcat cgaatgctca tgcgccagtt tgtgccaaat
     9001 gagaagattg atttttgcca agtgattgag tgtgagttag agatatagaa agaggtttgt
     9061 catcgcaaag aaaaaagcga catttgtatg tcaaaattgt gggtataatt cccctaaata
     9121 tctgggacgt tgccccaact gtgtgtcttg gtcttctttt gtggaagagg ttgaggttgc
     9181 cgaggtcaag aatgcgcgtg tgtccttgac aggtgagaaa accaagccca tgaaactagc
     9241 tgaggtgact tccatcaatg tcaatcgaac caagacggag atggaggaat tcaaccgtgt
     9301 gcttggaggc ggagtggtac caggaagtct cgtcctcatc ggtggggatc ctgggattgg
     9361 gaaatcaact cttctcctac aagtctcaac ccagttgtcc caagtgggga cagttctcta
     9421 tgtcagtggg gaggagtctg cccagcagat taaactacgt gcagagcgct taggtgatat
     9481 tgatagtgag ttttatctct atgcagagac caatatgcag agtgttcgtg cagaagtgga
     9541 gcgtatccag ccagactttc tcattattga ttccatccag accatcatgt ctcctgagat
     9601 ttcaggggtg caggggtctg tttctcaggt acgtgaagtg accgctgaac tcatgcagtt
     9661 ggccaagacc aataacattg ccatctttat cgtaggtcat gtgaccaaag aaggaacctt
     9721 ggctgggcct cgtatgttgg agcatatggt ggatacggtg ctttactttg aaggggagcg
     9781 tcaccacacc tttcgtattt tgagagcggt caaaaatcgt tttggttcca ctaatgagat
     9841 tgggattttt gagatgcagt cgggcggctt ggttgaggta ctcaatccga gtcaagtttt
     9901 cctagaagag cgtttggatg gggcgactgg ttcctccatc gttgtaacca tggaagggac
     9961 gcgtccgatt ttggcggagg ttcaggcttt ggtaacaccg accatgtttg gaaatgccaa
    10021 gcgtactacg acaggacttg attttaaccg tgctagcttg attatggctg ttttggaaaa
    10081 acgggcaggg cttctcttgc aaaatcagga tgcctatctc aaatctgctg gtggtgttaa
    10141 attggatgaa cctgccattg acttggctgt tgcagttgct attgcttcga gctacaaaga
    10201 caagccaact aatcctcagg aatgttttgt cggagaactg ggcttgacag gagagattcg
    10261 gcgcgtgaat cgtattgagc aacgcatcaa cgaagctgct aaactgggct ttactaagat
    10321 ttatgtacct cagaattcct tgacaggaat cactctgcct aaggaaattc aggtcattgg
    10381 cgtgacaacg attcaggaag tcttgaaaaa ggtctttgca taatccgtga caaattctct
    10441 taaaaatgat aagataggag aaatatttga ctatcaaatt ttcaaggagg gaatcgtgtc
    10501 gtattttgaa cagtttatgc aagccaatca ggcttatgtt gccctacatg ggcagttaaa
    10561 tctgccactt aaacctaaaa ccagagtagc cattgtgacc tgtatggact cacgtttgca
    10621 cgttgcgcaa gctctgggct tggcacttgg ggatgctcat atcttgcgga atgcaggtgg
    10681 tcgagtgact gaagacatga ttcgttcgct agttatttcc cagcaacaaa tggggacaag
    10741 agagattgtg gtattgcacc atacagactg tggtgctcag acctttgaaa atgaaccttt
    10801 tcaggagtat ttaaaagagg aattaggtgt agatgtgtca gaccaggact tcttgccctt
    10861 ccaagatata gaagagagtg tacgcgagga tatgcaactg cttatcgagt ctcccctaat
    10921 accagacgat gtcattatct ctggtgctat ttacaatgtt gatacaggaa gtatgacagt
    10981 cgtagaatta taaatacttc atttagaaag aaagtgtatg aagaaaagca gtattttatt
    11041 tatttttatt ttattgctat gtattggttt acagtatgaa accatctact atacggacgg
    11101 ttcgaggtca ggtgcggaat atggactaat gggagtttct atctttctag ctctctttta
    11161 catgattccg gctctttatt ttctcttccg tattgggaaa aaatgggaat tgccaaagaa
    11221 ggttttgatt ctgtctttat tgggagggat gttcctttca ggctggttgt ctagttttgc
    11281 taatacttat atacatgatt tactgggggt tcttttccca gatagtccat ttttaaatgc
    11341 ctttgaaagt gctattgtgg ctcctttggt agaagaaccc ttgaaattat tgccacttgt
    11401 ttttgttttg gctttgattc ctgtgcgaaa attaaaattt ttgtttttac ttggaattgc
    11461 ctccggtttg ggattccaaa tgattgagga tattggttat attcgtacgg atttgccaga
    11521 gggctttgac tttactattt cgcgaatttt agagcgtatc atctcaggaa ttgcctctca
    11581 ctggactttt tcaggtctag ctgtagtagg tgtttacttg ctttacagag cctataaagg
    11641 acagaaggtt ggcaagaaac agggtcttat tgtttaactc tccttttgtg gagttggaaa
    11701 cagagttgcc tttagcgatt ccagtggtta cggctattgc tctctatggt tattatcatg
    11761 cttattgctt tgttgagaaa cacaatgagt tgatgaccta gaatattttt caaaagaatg
    11821 atgcaagggt acaaatatgg tgcccttctt ttatttttga ttgaaaaata gtgcaaaaag
    11881 cgctacaatg gtagatggaa aatcttgtga aaagcacaag cgatacatat ataccggagg
    11941 aaatcatgtc tttttctgat ttaaagctgt ttgccctttc ttctaataaa gaattggcag
    12001 aacgtgtggc gcaggagatt gggatagagt tggggaaatc aagtgttcgc caattttcag
    12061 atggagagat tcaggtcaac attgaagaat caatccgtgg gaaacacgtc tttatcttac
    12121 aatcaactag ttcgcctgta aatgacaatc tgcttgaaat tttgattatg gtagatgctt
    12181 tgaagcgtgc gagtgcagag tctgtcaatg ttgtcatgcc ttactatggg tatgcacgtc
    12241 aggatagaaa ggcgagagcg cgtgagccaa tcacttcaaa acttgtcgca aatatgcttg
    12301 aagtagctgg agtggatcgt ttattgacca tcgacttgca tgctgcgcaa attcaaggat
    12361 tctttgatat tcctgtggat catttgatgg gtgctcctct aattgcagat tattttgagc
    12421 ggcgtggtat ggttggttct gactatgtgg ttgtcagccc ggaccatgga ggggtgactc
    12481 gtgctcgtaa gttggcagaa tttttgaaaa catctatcgc tattattgat aaacgtcgta
    12541 gcgttgataa gatgaatact agtgaagtta tgaacatcat cggtaaggtt gaaggcaaga
    12601 cttgtatctt gattgatgat atgattgata ccgctggaac gatttgtcat gcggcagatg
    12661 ctcttgcgga agctggtgct gttgaagtct atgcaagctg tacgcaccca gttctttctg
    12721 gtcctgctac ggacaatatc caaaaatcag ctattaagaa attggttgtt ttggatacca
    12781 tctatctgcc agaagagcgt ttgattgata agattgagca gatttcaatc gctcatctcc
    12841 taggggatgc tatcgtacgt attcatgaaa aacgaccact ttctccactt ttcgatattg
    12901 agaaaaaaat ttaatgacca agcctgagat gattctcagg ttttttcgtc ttttttccga
    12961 ataaatggat agtagcggtg aatctagtaa agctagattt aaaactgtga tataataaaa
    13021 agagaagaaa tatgactata cgtcatcaga agtttcagcg accatcattt ttgaacagtg
    13081 atagcacttg aatcgacgct ttctaaggag aattctagta ggtataccag tcgtttcaag
    13141 ataaggaatt ttagaaggtt tttgaaagtc atatttcttc aattggtttc cgcactcagg
    13201 gcaagatggg gcgtcgtagt ccagtttggc gatgatttcc ttgtgtgtat ccttattgat
    13261 gatgtttaaa atctggacat tagggtcttt aatgtctagt aattttgtga taaaatgtaa
    13321 ttgttccata tgattctttc taatgagttg ttttgtcgct tttcattata ggtcatatgg
    13381 gacttttttt ctacacaaaa taggctccat aatatccata ggggatttac ccactatgga
    13441 tattatggag ccattttaca acagtgcctc aaattcagat actgacatac ctaattgctg
    13501 gctggcaacc tcagaagtca gaagaccttg gcgtactatg tctaggaagg caaaaagttt
    13561 cctttctgcc cttccttcaa ctttcccacg ctctagtcct tgttcaaggc cttcagccct
    13621 agcagtttcc aaggcatagt cctgtgctaa caagacttgt tcttctcgca tatgtagttg
    13681 actaaacatt ttcctgtcct cctcggacca gctcttgtag tccagcagtt gatttgcttg
    13741 gctaatggct cgttgcggtt gctgggtaaa gggcttgttg ccgaaaaact ccaaccatgg
    13801 cttgcgaacc ttgtctttgc tggtttctct gtatttttta attccaagaa tgccatctta
    13861 accagatggt tttcctgtcc attgttggta atcgccaata cctcacctgt tgtgtcttcg
    13921 cgcatactaa agctatgaaa agccaggtca tctgagaaat aattactatc cacgatagca
    13981 atggcgtaaa caggagcgat gtgtttgtag ctctagtgag tatcaccttc tcgctgacga
    14041 attttttcaa gattttgatt aacctgactg cacaggtaag tccacaagtg attgatgaaa
    14101 aaattctgat gatggacttg aatctcaata attacttgag taccgttatc caactccgcc
    14161 aagacgtcta tactggtata aaaatcctgc accgagtaag gcatggagag taatacgtga
    14221 atatcgcttc cctccaaaat ggtcacattt tttgctggca agtccagcat atcgcgaata
    14281 aattgacaag tgatttctgg attgctgaat attttcttag caatcaaatc attagttggg
    14341 ctgatgcccg gatgtctgag aatcctccta ttcctccttc tatagtgagt tgaaataaga
    14401 tgtgaataac tctatcagga aagtcaaatt aatttataga
//
LOCUS       DBEJAU010000049        14440 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC323 isolate 683620
            SAMN38261939-rid24807223.denovo.049, whole genome shotgun sequence.
ACCESSION   DBEJAU010000049 DBEJAU010000000
VERSION     DBEJAU010000049.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261939
            Sequence Read Archive: SRR26833919
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 14440)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14440)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576303.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576303.1
            Genome Coverage       :: 154x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/19/2025 01:05:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,121
            CDSs (total)                      :: 2,078
            Genes (coding)                    :: 1,943
            CDSs (with protein)               :: 1,943
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 36
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 72 of 135
            Pseudo Genes (incomplete)         :: 63 of 135
            Pseudo Genes (internal stop)      :: 51 of 135
            Pseudo Genes (multiple problems)  :: 46 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14440
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261939-rid24807223.denovo.049"
                     /strain="GPSC323"
                     /isolate="683620"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            complement(111..1160)
                     /locus_tag="ACL29Z_001698"
     CDS             complement(111..1160)
                     /locus_tag="ACL29Z_001698"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HGR0069967.1"
                     /translation="MKDLFLKRKQAFRKECLGYLRYVLNDHFVLFLLVLLGFLAYQYS
                     QLLQHFPENHWPILLFVGITSVLLLLWGGIATYMEAPDKLFLLVGEEEIKLHLKRQTG
                     ISLVFWLFVQTLFLLLFAPLFLAMGYGLPVFLLYVLLLGVGKYFHFRQKASKFFTETG
                     LDWDYVISQESKRKQVLLRFFALFTQVKGISNSVKRRAYLDFILKAVQKVPGKIWQNL
                     YLRSYLRNGDLFALSLRLLLLSVLAQVFIEQAWIATAVVVLFNYLLLFQLLALYHAFD
                     YQYLTQLFPLDKGQKEKGLQEVVRGLTSFVLLVELVVGLITFQEKLALLALLGAGLVL
                     LVLYLPYQVKRQMQD"
     gene            complement(1157..1888)
                     /locus_tag="ACL29Z_001699"
     CDS             complement(1157..1888)
                     /locus_tag="ACL29Z_001699"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000889926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGR0069968.1"
                     /translation="MLEIKNLTGGYVHVPVLKDVSFTVESGQLVGLIGLNGAGKSTTI
                     NEIIGLLAPYSGSININGLTLQGDATSYRKQIGYIPETPSLYEELTLREHIETVAMAY
                     GIEQKVAFERVEPLLKMFRLDQKLDWFPVHFSKGMKQKVMIICAFVVDPSLFIVDEPF
                     LGLDPLAISDLIQLLEVEKQKGKSILMSTHVLDSAEKMCDAFVILHKGEVRAKGNLLQ
                     LREAFDMPEASLNDIYLALTKEEDL"
     gene            1956..2366
                     /locus_tag="ACL29Z_001700"
     CDS             1956..2366
                     /locus_tag="ACL29Z_001700"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006150090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HIT family protein"
                     /protein_id="HGR0069969.1"
                     /translation="MSDCIFCKIIAGEIPASKVYEDEQVLAFLDISQVTLGHTLVVPK
                     EHYRNLLEMDATSASQLFAQVPKVAQKVMKVTKAAGMNIISNCEEVAGQTVFHTHVHL
                     VPRYSADDDLKIDFIAHEPDFDKLAQVAETIKNA"
     gene            2376..2663
                     /locus_tag="ACL29Z_001701"
     CDS             2376..2663
                     /locus_tag="ACL29Z_001701"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000777751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0069970.1"
                     /translation="MKLSNLLLFAGAAAGSYLVTKNRQTITDEVLNTTDRVQAIKDDV
                     DIIQNSLQIINQQKELIKEYQEDLTYKFKVLEKDIQTRLAVIKEMQGTEDK"
     gene            2825..3064
                     /locus_tag="ACL29Z_001702"
     CDS             2825..3064
                     /locus_tag="ACL29Z_001702"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0069971.1"
                     /translation="MHHNLGNSYSIKIKKQTRKLGTDCSKHRFKVVDRTDEVSSKHCF
                     EVVDRTDEVSNHTHDKPTLTWFEEIFEEYHSPFHN"
     gene            complement(3386..4513)
                     /gene="dnaJ"
                     /locus_tag="ACL29Z_001703"
     CDS             complement(3386..4513)
                     /gene="dnaJ"
                     /locus_tag="ACL29Z_001703"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001066288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0051082 - unfolded protein binding
                     [Evidence IEA];
                     GO_process: GO:0006457 - protein folding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone DnaJ"
                     /protein_id="HGR0069972.1"
                     /translation="MNNTEFYDRLGVSKNASADEIKKAYRKLSKKYHPDINKEPGAED
                     KYKEVQEAYETLSDDQKRAAYDQYGAAGANGGFGGAGGFNGAGGFGGFEDIFSSFFGG
                     GGSSRNPNAPRQGDDLQYRVNLTFEEAIFGTEKEVKYHREAGCRTCNGSGAKPGTSPV
                     TCGRCHGAGVINVDTQTPLGMMRRQVTCDVCHGRGKEIKYPCTTCHGTGHEKQAHSVH
                     VKIPAGVETGQQIRLAGQGEAGFNGGPYGDLYVVVSVEASDKFEREGTTIFYNLNLNF
                     VQAALGDTVDIPTVHGDVELVIPEGTQTGKKFRLRSKGAPSLRGGAVGDQYVTVNVVT
                     PTGLNDRQKVALKEFAAAGDLKVNPKKKGFFDHIKDAFDGE"
     gene            complement(4915..5271)
                     /locus_tag="ACL29Z_001704"
     CDS             complement(4915..5271)
                     /locus_tag="ACL29Z_001704"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000114361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (guanine-N7)-methyltransferase"
                     /protein_id="HGR0069973.1"
                     /translation="MSVLDEEYLKNTRKVYNDFCNQADNYRTSKDFIDNIPIEYLARY
                     REIILAEHDSCIKNDEAVRNFVTSVLLSAFVSAMVPAMISLEIQTYKFVIPFIIGMIW
                     TVVLFLMINWNYIGKY"
     gene            complement(5273..7096)
                     /gene="dnaK"
                     /locus_tag="ACL29Z_001705"
     CDS             complement(5273..7096)
                     /gene="dnaK"
                     /locus_tag="ACL29Z_001705"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002946936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_process: GO:0006457 - protein folding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone DnaK"
                     /protein_id="HGR0069974.1"
                     /translation="MSKIIGIDLGTTNSAVAVLEGTESKIIANPEGNRTTPSVVSFKN
                     GEIIVGDAAKRQAVTNPDTVISIKSKMGTSEKVSANGKEYTPQEISAMILQYLKGYAE
                     DYLGEKVTKAVITVPAYFNDAQRQATKDAGKIAGLEVERIVNEPTAAALAYGLDKTDK
                     EEKILVFDLGGGTFDVSILELGDGVFDVLSTAGDNKLGGDDFDQKIIDHLVAEFKKEN
                     GIDLSTDKMAMQRLKDAAEKAKKDLSGVTSTQISLPFITAGEAGPLHLEMTLTRAKFD
                     DLTRDLVERTKVPVRQALSDAGLSLSEIDEVILVGGSTRIPAVVEAVKAETGKEPNKS
                     VNPDEVVAMGAAIQGGVITGDVKDVVLLDVTPLSLGIETMGGVFTKLIDRNTTIPTSK
                     SQVFSTAADNQPAVDIHVLQGERPMAADNKTLGRFQLTDIPAAPRGIPQIEVTFDIDK
                     NGIVSVKAKDLGTQKEQTIVIQSNSGLTDEEIDRMMKDAEANAEADKKRKEEVDLRNE
                     VDQAIFATEKTIKETEGKGFDAERDAAQAALDDLKKAQEDNNLDDMKAKLEALNEKAQ
                     GLAVKLYEQAAAAQQAQEGAEGAQATGNAGDDVVDGEFTEK"
     gene            complement(7576..8100)
                     /gene="grpE"
                     /locus_tag="ACL29Z_001706"
     CDS             complement(7576..8100)
                     /gene="grpE"
                     /locus_tag="ACL29Z_001706"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000046028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide exchange factor GrpE"
                     /protein_id="HGR0069975.1"
                     /translation="MAQDIKNEEVEEVQEEEVVETAEETTPEKSELDLANERADEFEN
                     KYLRAHAEMQNIQRRANEERQNLQRYRSQDLAKAILPSLDNLERALAVEGLTDDVKKG
                     LGMVQESLIHALKEEGIEEIAADGEFDHNYHMAIQTLPADDEHPVDTIAQVFQKGYKL
                     HDRILRPAMVVVYN"
     gene            complement(8127..9161)
                     /gene="hrcA"
                     /locus_tag="ACL29Z_001707"
     CDS             complement(8127..9161)
                     /gene="hrcA"
                     /locus_tag="ACL29Z_001707"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011999912.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="heat-inducible transcriptional repressor HrcA"
                     /protein_id="HGR0069976.1"
                     /translation="MVTERQQDILNLIIDIFTKTHEPVGSKALQESINSSSATIRNDM
                     AELEKQGLLEKAHTSSGRMPSVAGFQYYVKHSLDFHRLAENEVYEIVKAFDQEFFKLE
                     DILQEAANLLTDLSGCTVVALDVEPSRQRLTAFDIVVLGQHTALAVFTLDESRTVTSQ
                     FLIPRNFLQEDLLKLKSIIQERFLGHTVLDIHYKIRTEIPQIIQRYFTTTDNVIDLFE
                     HIFKEMFNENIVMAGKVHLLNFANLEAYQFFDQPQKVALEIREGLREDQMQNVRVADG
                     QESCLADLAVISSKFLIPYRGVGILAIIGPVNLDYQQLINQVNVVNRVLTMKLTDFYR
                     YLSSNHYEVH"
     gene            complement(9325..9834)
                     /locus_tag="ACL29Z_001708"
     CDS             complement(9325..9834)
                     /locus_tag="ACL29Z_001708"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001088691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2812 domain-containing protein"
                     /protein_id="HGR0069977.1"
                     /translation="MNSRVEFRIFTIVDLDKEEEHLHEMHLKGWRYRTSRFGLFYFDQ
                     CQPDDVIYRIYDSRFLKKYKHELQDFRDRGWELIGAGSCSILRKSSSDLLPEDQVYMS
                     KGLKWEVMRSRLRSCTTTFLGGLVVCTSLFREDLSMSFFLIFVLYAFLISYLIHGYFR
                     LKRKYRVDE"
     gene            10442..12775
                     /gene="hsdR"
                     /locus_tag="ACL29Z_001709"
     CDS             10442..12775
                     /gene="hsdR"
                     /locus_tag="ACL29Z_001709"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003678 - DNA helicase activity [Evidence
                     IEA];
                     GO_function: GO:0015666 - restriction
                     endodeoxyribonuclease activity [Evidence IEA];
                     GO_process: GO:0009307 - DNA restriction-modification
                     system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="EcoAI/FtnUII family type I restriction enzme
                     subunit R"
                     /protein_id="HGR0069978.1"
                     /translation="MVEFIKSKKEMSEEDIKANFITPAIVSKGWKNGEHIAYEEYFTD
                     GRIEVRGDKARRKEGKKSDYSLYYQFGTRIAIVEAKDNKHSVRAGLQQAIEYGEILDV
                     PFVYSSNGDGFIEHDRITREERELELDEFPTREELFSRMTKEKGLTYEITEAISTPYY
                     TDAFSMKTPRYYQQIAINRTIETVARGQKRVMFVMATGTGKTFMAFQIIHRLRKAGLA
                     KRVLFLADRNILVDQTMAEDFKPFEKVMTKITPKLLTAPEKLNSFEIYLGLYQQLTGE
                     DGTETHYQKFDKDFFDLIVIDEAHRGSAKENSNWRKIIDYFSSATQIGMTATPKETKN
                     ASNTEYFGEPIYTYSLKQGIEDGFLAPYRVMRVNLDVDVDGYRPETGKVDANGQLIED
                     RYYSRKDFDKTIVIDDRTQRVAKFVSDYMKQNNARFDKTIVFCVDIDHAERMRAALVK
                     ENLDLVQEDYRYVMQVTGDNAEGKAQLDNFMDVNSNFPAIVTTSKLLTTGVNAKTCRL
                     IVLDSNIQSMTEFKQIIGRGTRLYPQKGKEFFTIIDFRNVTNLFADPDFDGEPVKVLE
                     TGAKTVSGSTPGFVDEEGDPVEKYIVTDKQVTILNSTVQVLDENGKLITESLTDYTRK
                     NILGSYATLNDFITVWHTADKKKLILDELYKKGVYLDAIRESEGISEQEIDDFDLLLK
                     LAYGQKELTKTERINKLKQSGYLYKYSEEARAVLEILLNKYMDKGIGELESIETLKLP
                     EFQIYGGTFKIINTYFGDKKRYLQAIKELEQELFTVA"
     gene            12788..14251
                     /locus_tag="ACL29Z_001710"
     CDS             12788..14251
                     /locus_tag="ACL29Z_001710"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000029054.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0008170 - N-methyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="N-6 DNA methylase"
                     /protein_id="HGR0069979.1"
                     /translation="MSITSFVKRIQDITRNDAGVNGDAQRIEQMSWLLFLKIYDSREM
                     VWELEEDEYESIIPEELKWRNWAHAQNGERVLTGDELLDFVNNKLFKELKELEITSNM
                     PIRKTIVKSAFEDANNYMKNGVLLRQVINVIDEVDFNSPEDRHSFNDIYEKILKDIQN
                     AGNSGEFYTPRAATDFIAEVLDPKLGESMVDLACGTGGFLTSTLNRLSSQRKTSEDTK
                     KYNTAVFGIEKKAFPHLLAVTNLFLHEIDDPKIVHGNTLEKNVREYTDDEKFDIIMMN
                     PPFGGSELETIKNNFPAELRSSETADLFMAVIMYRLKENGRVGVILPDGFLFGEGVKT
                     RLKQKLVDEFNLHTIIRLPHSVFAPYTGIHTNILFFDKTKKTEETWFYRLDMPDGYKN
                     FSKTKPMKSEHFNPVRDWWENREEILEGKFYKSKSFTPSELAELNYNLDQCGFPKEEE
                     EILNPFELIQNYQAERATLNHKIDNVLADILQLLEDK"
     gene            14251..>14440
                     /locus_tag="ACL29Z_001711"
     CDS             14251..>14440
                     /locus_tag="ACL29Z_001711"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000187211.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I restriction endonuclease"
                     /protein_id="HGR0069980.1"
                     /translation="MTPEQLKASILQRAMEGKLVPQNPNDEPASELLKRIKAEKEKLI
                     SEGKIKRDKKETEIFRGDD"
BASE COUNT         4489 a         2904 c         2813 g         4234 t
ORIGIN      
        1 agattttcga agagtataag tctctacgga ccaaccatta tcctgtagta acaaaaaaga
       61 agctgagaca gactgaactc aacttctttt ttagtgtcgt atcagcaatg ttagtcctgc
      121 atctgacgtt ttacctgata aggcaaatac aagactagta aaaccaaacc agctcctagt
      181 aaggctagaa gggccagttt ttcttggaag gtaatcaacc caacaactaa ttccacaagt
      241 aaaacaaaac tggtcaatcc tcgaactacc tcctgtaagc ctttttcctt ttgccccttg
      301 tccagcggaa agagttgggt caaatactgg tagtcaaagg catgatagag ggccagcaac
      361 tggaagagca agaggtagtt aaagagaact accactgctg tcgcaatcca agcttgctcg
      421 ataaaaacct gcgccagtac ggaaagtaag agaagacgaa gactgagagc aaagaggtcg
      481 ccatttcgca gataagaacg cagatagaga ttttgccaaa tcttcccagg caccttctga
      541 acagccttta agataaagtc cagataggca cgacgcttaa cgctgtttga aattcccttg
      601 acctgcgtaa agagggcaaa gaaacgaagc aagacttgct tacgcttgct ttcttgggaa
      661 atgacatagt cccagtccag cccagtttca gtgaaaaatt tgctggcctt ttgacgaaag
      721 tggaaatatt ttcctacccc caataaaagc acatagagca gaaaaactgg caagccataa
      781 cccattgcta aaaataaagg cgcaaataac agcaagaaaa gggtctgtac aaagagccaa
      841 aagactaggg aaatgccagt ttgacgcttg agatggagct taatttcctc ttctccaact
      901 aagagaaaga gcttgtctgg agcctccata taggtggcaa ttcctcccca aagtaaaagt
      961 aaaacagacg taattcctac aaacaaaagg ataggccaat gattttcagg aaaatgttgt
     1021 aagagttgac tgtactggta ggctagaaag cccaacagga caagcaggaa caagacaaag
     1081 tggtcattga gcacatagcg cagataacca agacactcct tacgaaaggc ctgctttctc
     1141 tttaaaaaca agtctttcat aggtcctcct cttttgtcag agccaagtaa atatcattca
     1201 aactagcctc aggcatatca aaggcttcgc gtagttgcag gagattgcct ttggcacgca
     1261 cctctccctt gtgaagaatg acaaaggcat cacacatctt ctccgccgaa tccagcacgt
     1321 gggtactcat gagaatagac ttgccctttt gcttctccac ttccaaaagc tgaatcaaat
     1381 cagaaatagc tagcggatca agaccaagga aaggctcatc cacgatgaaa agacttggat
     1441 ccaccacaaa agcacagata atcatgacct tctgcttcat cccttttgaa aaatgaacag
     1501 ggaaccagtc taatttctgg tccagacgga acatctttaa caagggctct actcgttcga
     1561 aagccacttt ttgctcaata ccgtaagcca tagcaaccgt ttcgatatgc tctctgaggg
     1621 tcaattcctc atacagacta ggcgtctcag gaatgtagcc aatctgcttg cggtagctag
     1681 tcgcatctcc ttgcagagtc aggccattga tattgatgga gccactataa ggtgccaaca
     1741 gaccgataat ctcattgatc gtcgttgatt tcccagcacc attgagacca atcaaaccga
     1801 ccaactgccc actttcaaca gtaaaggaca catctttcaa aacaggaaca tgaacatagc
     1861 cacctgtcag gtttttaatt tctaacatat tttctccaaa tctggtataa tgtagctata
     1921 ttatatcaaa attcagtaca gtagaggtag attttatgtc agattgcatt ttttgtaaaa
     1981 tcatcgcagg ggaaattcct gcttcaaaag tatatgaaga tgagcaggtc cttgcctttc
     2041 ttgatatctc tcaagtaaca ctaggacaca ccttggtcgt gccaaaagaa cactatcgca
     2101 atcttttgga gatggatgct acgagcgcca gccaactctt tgcccaagta ccaaaagtag
     2161 ctcaaaaagt catgaaagtc actaaggctg ctggtatgaa tatcatttcc aactgtgaag
     2221 aagtcgctgg tcaaacagtt tttcatactc acgttcacct tgtgcctcgc tacagtgctg
     2281 acgatgacct caagattgat tttatcgccc acgaaccaga ctttgacaaa cttgctcaag
     2341 tcgctgaaac catcaaaaac gcttaaggag ttgctatgaa attatccaac ctactgctat
     2401 ttgcaggagc tgcagccgga agttatctgg ttacaaaaaa tcgccaaacc atcacagatg
     2461 aagtcttgaa taccactgac cgcgttcaag ctatcaagga cgatgtggat attatccaaa
     2521 acagcctgca aatcattaac cagcaaaaag aacttatcaa ggaataccaa gaagacttga
     2581 cttacaagtt taaggtcttg gaaaaggata tccagactag actagctgtg ataaaagaaa
     2641 tgcagggaac tgaagataag taaaaagagc cccccggctc ttttttaaaa cgtaaacaag
     2701 ttatagtgaa ttgaatttag aatagcacat catagtttct aaagcattgc tagagattac
     2761 tttaaaatcc tcttatcaat ttgttcatat tctatttcaa tctactatat atatcccatc
     2821 aactatgcat cataatttag gtaactcata ctcaataaaa atcaaaaagc aaactagaaa
     2881 gctaggcaca gactgctcaa aacaccgttt taaggttgtg gatagaactg acgaagtcag
     2941 ctcaaaacac tgttttgagg ttgtggatag aactgacgaa gtcagtaacc atacccatga
     3001 caagccgacg ctgacgtggt ttgaagaaat ttttgaagag tatcattcac catttcacaa
     3061 ctaaatcgaa gactttctgc cgtaatgaaa acacctgaaa cagcttggtt tcagctgtcc
     3121 ggaaacttta agacttaggt tcaaagttta ggtatggaac ttcgaaggag gtcgctaccg
     3181 tccgtcatta cttaggaaag tcttaaaaaa tctataaagt aaaaagagcc cgacagctct
     3241 ttttgtttat actcaatgaa aatcaaaaag caaactagga aactagccac gggctgctca
     3301 aaacactgtt ttgaggttgt agatacgact cacatatata cggcaagccg acgctgacgt
     3361 ggtttgaaga gattttcgaa gagtattatt ctccatcaaa ggcatcttta atatggtcaa
     3421 agaagccttt tttctttgga tttactttca agtcaccagc agccgcgaat tctttcaagg
     3481 ctactttttg gcggtcgttc aagcctgtcg gtgttacgac attaacagta acgtattggt
     3541 caccaactgc accgccacga aggctcggtg cccccttact acgtaggcgg aatttcttac
     3601 cagtctgagt tccctctgga ataaccaatt caacatcacc gtgaacagtt ggaatatcta
     3661 ctgtatcacc aagagccgct tggacaaagt tgaggttgag attgtagaag atagtcgttc
     3721 cttcacgttc aaacttgtcg ctagcttcta cagaaactac tacatacaag tccccataag
     3781 gtccaccgtt aaagcctgct tcgccttgac cagcgaggcg aatttgttga cctgtttcca
     3841 caccagcagg gattttcaca tgtacgctat gagcttgttt ctcatgacct gttccatgac
     3901 aggttgtaca tggatatttg atttcttttc ctcgaccgtg acagacatca caggttactt
     3961 ggcgacgcat cataccaaga ggagtctgcg tatcgacgtt aatgacacca gcgccatgac
     4021 agcgtccaca agtgactgga cttgtccctg gcttagcacc agagccatta catgtacgac
     4081 agccagcttc acgatgatac ttaacttcct tctcagttcc gaagatagct tcttcaaagg
     4141 tcaaattgac acgatactgg agatcatctc cttggcgagg agcgtttgga ttgcgcgaag
     4201 aaccgcctcc gccgaagaaa cttgagaaaa tatcctcaaa accaccgaag ccacctgccc
     4261 cattgaaacc accagctcca ccaaaaccac cattggcgcc tgcagcacca tactggtcat
     4321 aggcagcacg tttttggtcg tcactcaaag tctcataggc ttcttgaact tccttgtact
     4381 tgtcctcagc accaggctcc ttgttgatat ctgggtgata ttttttggaa agcttacgat
     4441 aagccttttt gatttcgtct gccgaagcgt ttttggatac ccccagacga tcataaaatt
     4501 cagtattgtt cataattcaa gatacaaagg gcgtcaaacg gacacagcca tctaggagtt
     4561 ttgacgacgg acgcttacgt cctagaaaaa actatctttt tggcacagtc catagcccgt
     4621 gttcagttac gaacaccctt attcctttct attgatgttc tgaatcgaac caccatttag
     4681 gtcgggttca attcctttct tttatattta gtaagaaatt ctgaaacccg tgttcagtta
     4741 cgaacactct ttgttccttt ctattgatga gacaaaactc aaacaaatga gattccgtcc
     4801 ctttttatcg aaaaacagag gctgggttgc aacctctgca aataagtaaa ttaactttat
     4861 tttgatttta aatatcctat aagtacagaa atatttatat atttttgtct cttcttagta
     4921 tttgcctata taattccaat tgatcataag aaataaaact actgtccaaa tcataccaat
     4981 tatgaacggt attacaaatt tatatgtttg tatttctaat gatatcatag ctggtaccat
     5041 cgccgataca aatgcagaca acaatactga ggtaacaaaa ttccttaccg cttcatcatt
     5101 tttgatacaa ctatcatgtt cagctaatat aatttctcta tatctagcta aatattctat
     5161 tggaatatta tcaataaaat cttttgatgt tctatagtta tcagcttgat tacaaaaatc
     5221 attataaact tttcgtgtat tttttagata ctcttcatcc aatacactca tcttactttt
     5281 ccgtaaactc tccgtctacg acgtcatcgc ctgcgtttcc tgttgcttgt gcgccttctg
     5341 ctccttcttg agcttgttgc gctgctgcgg cttgttcgta gagtttaaca gcaagtcctt
     5401 gagctttttc gttcaatgct tcaagttttg ctttcatgtc gtccaagttg ttgtcttctt
     5461 gagctttctt aaggtcatca agggcagctt gggcagcgtc acgttctgcg tcgaagcctt
     5521 taccttcagt ttccttgatt gtcttttcag tcgcaaagat tgcttggtct acttcattac
     5581 gaaggtctac ttcttcttta cgtttcttat cggcttcagc gtttgcttct gcatctttca
     5641 tcatgcggtc gatttcttcg tcagtcaaac ctgagttcga ttggatgaca atagtttgtt
     5701 ctttttgagt tccaaggtct ttggccttaa cagacacgat accgttcttg tcgatgtcaa
     5761 atgttacttc gatttgagga attccacgag gtgcagctgg gatatcagtc aattggaagc
     5821 gtccaagagt cttgttatct gctgccattg ggcgttcacc ttgaagaacg tggatatcaa
     5881 cggctggttg gttgtctgct gctgttgaga agacttgtga tttagatgtt gggattgtag
     5941 tgttgcgatc gataagtttt gtaaatactc cacccattgt ttcgatacca agtgacaatg
     6001 gcgttacatc aagaaggaca acgtccttga catcaccagt aatcacacca ccttggatag
     6061 ccgcacccat agcaactact tcatcagggt ttactgattt gtttggttct ttaccagttt
     6121 cagctttaac agcttcaaca acggcaggga tacgagttga accaccaaca aggataactt
     6181 cgtcgatttc tgacaagctc aaacctgcat ctgaaagggc ttgacgaact ggaacttttg
     6241 tacgttcaac aaggtcacga gtcaaatcat caaatttcgc acgagtcaaa gtcatttcca
     6301 agtgaagagg tccagcctca cctgcagtga taaatggcaa gctgatttgt gttgaagtta
     6361 caccagaaag gtctttcttc gctttttcag ccgcatcttt caaacgttgc attgccatct
     6421 tgtcagtaga caagtcgata ccgttttctt tcttgaattc tgctaccaag tggtcaatga
     6481 ttttttggtc aaagtcgtca ccaccaagtt tgttgtcccc tgcagttgac aatacgtcga
     6541 agacaccgtc acccaattca aggatagaga cgtcgaatgt accaccacca aggtcaaata
     6601 ccaagatttt ttcttctttg tcagtcttgt ccaaaccata agcaagagct gctgcagttg
     6661 gttcgttaac aatacgttct acttcaagac cagcaatttt accagcgtct tttgttgctt
     6721 gacgttgagc gtcgttgaag taagctggaa ctgtgataac agctttggtt actttctcac
     6781 caaggtagtc ttcagcgtag cctttcaagt attgaaggat catagctgag atttcttgtg
     6841 gagtgtattc ttttccattt gcagaaactt tttcagaagt tcccatctta gatttgatag
     6901 agataactgt atctgggttt gtgactgctt gacgttttgc agcatcacca acgatgattt
     6961 ctccgttttt gaatgagact acagatggag ttgtgcggtt tccttctggg tttgcgatga
     7021 ttttgctttc agttccttca agaactgcaa ctgctgagtt tgttgtacct aagtcaatac
     7081 cgataatttt agacatgtgt ttttctcctt gttagttaat tttctatttt tctttttgat
     7141 actcttctta agtggcgacg ccgtcagagc ttgacttggt caatctcttt gactaaactt
     7201 tgagcctaag gtctcaaaat ttgcgcaaat agcgccacgg cgaagagtat cgtgtttggt
     7261 tcgcttcgct cactattaca aagccaaaca tattttatct ttcttcatag tttattgtcg
     7321 tttcggacaa gttttctatt atgtaaattg cgacacgagg agtcgaaatc gattttattt
     7381 cgacgacgag ttagtaagga agctaggcaa acgccataac gattgccgtt ttctgacgag
     7441 ttgctttagc taccgtcaga attgccgaat cgaacacgcc ctaagctctg agtaaaaaag
     7501 atagattttc ttgtgttcat cgaacacttc gtcaatctcc tatttttact gcgagctttt
     7561 tacgggcttt atatcttagt tatacaccac taccattgct gggcgtagga tgcggtcatg
     7621 gagtttgtag cctttttgaa agacttgagc gatggtatct actgggtgtt catcgtctgc
     7681 tgggagagtt tggatggcca tatggtagtt atggtcaaat tcgccatctg ctgcgatttc
     7741 ttcaattcct tcttctttca aagcgtgaat caagctttct tgcaccatcc ccaagccctt
     7801 cttcacatca tctgtcaaac cttcaactgc aagtgcacgc tcaaggttgt caagagatgg
     7861 taagattgct tttgccaagt cctggctacg ataacgttgc aagttttgac gttcttcatt
     7921 ggcacggcgt tggatatttt gcatttctgc atgagcgcga agatatttgt tttcgaactc
     7981 atctgcacgt tcatttgcca agtccaactc agacttttca ggagttgttt cttcagctgt
     8041 ttccacaact tcctcttctt gaacttcttc tacttcttca ttttttatat cttgggccat
     8101 gttcgcctcc tttaatgatt tcaatcttaa tgtacttcgt aatgattact gctgaggtag
     8161 cggtaaaaat ctgtcaactt catggtcaaa acacggttga ccacattgac ttgattgatt
     8221 agctgttggt aatccagatt aactggaccg ataatggcta gaattccaac tccccgataa
     8281 ggaatgagga acttactact aatcaccgct aggtcagcta aacaggactc ttgaccgtct
     8341 gcaacacgaa cattttgcat ctgatcctca cgcaacccct cacgaatctc caaggccacc
     8401 ttttgcggtt ggtcaaagaa ctgataggct tctagattgg caaaattcaa gagatggacc
     8461 ttgcccgcca tcacaatgtt ttcgttgaac atttccttaa agatgtgttc aaagagatcg
     8521 atgacattat ccgttgttgt aaagtaacgc tggataatct gcggaatctc cgtccgaatc
     8581 ttgtagtgaa tatctaaaac ggtgtgaccg aggaaacgtt cctgaatgat gctcttcagt
     8641 ttcagcaaat cctcctgcaa gaagttcctt ggaatcagaa actgactagt aaccgttcgc
     8701 gactcgtcta gggtaaatac cgccaaggct gtatgttgcc ccaaaacaac gatatcaaag
     8761 gctgtcaaac gttgcctgct cggctcaaca tccagtgcca ctaccgtaca gccactcagg
     8821 tctgttagca agttagcagc ctcttgcaga atatcctcca atttgaagaa ttcctgatca
     8881 aaggctttga caatctcata tacctcattt tcagccagcc ggtgaaaatc cagtgagtgt
     8941 ttcacatagt actgaaaacc agcaacactt ggcatccgac cgcttgaagt atgagccttc
     9001 tcaagcaacc cttgtttttc tagttccgcc atgtcattac gaatggttgc actgctagag
     9061 ttaatagact cttgcaaggc ttttgatccg acaggttcgt gcgttttggt aaagatgtca
     9121 ataatcagat ttaaaatatc ctgctgacgc tctgtaacca tctcatcact cctctctgtc
     9181 tgatcaatta gcactcaatg catccaagtg ctaacttatg attctattat acacccttaa
     9241 aggagaatgt caagacaaaa actcaaaaaa ttagcactct tttatcaaga gtgctaaaaa
     9301 tcaatctgaa gacctagaac cttgctattc atctactcgg tatttccttt ttagtctgaa
     9361 ataaccatga attagataag aaatcagaaa agcatataaa acaaaaataa gaaagaaaga
     9421 catagaaaga tcctctctaa acaaactcgt acaaacaaca agaccaccta agaaagtagt
     9481 tgtacaggaa cgaagtctag atcgcataac ttcccatttg agccccttac tcatatagac
     9541 ttgatcctct ggaagtaaat cagaagacga tttacgaaga atcgaacaag aacctgctcc
     9601 tatcaattcc caacctctat ctctaaaatc ttgcagttca tgcttatatt ttttaagaaa
     9661 tctagaatca tagatacggt agatgacatc gtctggttga cattggtcaa aatagaacaa
     9721 accaaaacga ctcgttctat acctccaacc tttcaaatgc atctcatgta aatgttcttc
     9781 ttccttgtcc aaatcaacaa tggtgaaaat ccgaaattct actctgctat tcattgtctt
     9841 accccaaaat tagaaaacat gcctggcgtt atttattaga taattctttc cacttttgac
     9901 tcaatctcca aaaaatataa gaaatctgaa tcgcaaaaac tatcaataaa acccaatcta
     9961 ttatgaaaat caaaaacact ttccaactga aagaactacc tccagtgaca aactttgaga
    10021 aaaacggtag tagagctaaa aagagaagta aaataggaag catccgcatt gttaaaatcc
    10081 gtttggcata aaaaaatctt tatttaaact aaaatattat agcaaaattt acgccagttt
    10141 ttgaacggct gatgtagata ttttatactt tcaaaatgtt taaatgtgat tatttatttt
    10201 tgaaaaatag ctcaccagcc cgactgaaag tgcttataga atgataataa gtcgcctgcc
    10261 gaaaacagcg gaaaatagcg gtgttatgcg gagataatct gacgcgatgc gaaagtatat
    10321 tgcatactta ttttcaacaa tttagcagag tatttttata agtgtgatat aatagaagta
    10381 taatttgttc tgatagttta ttttatggag aagtagattt ttagaatgcg gagggttcaa
    10441 tatggttgag tttataaagt ctaagaaaga aatgagtgag gaggatatta aagcaaattt
    10501 catcactcct gctattgtat ccaaaggatg gaaaaatggt gagcatatcg cttacgaaga
    10561 atacttcact gatggtcgaa ttgaggttag aggagataag gctcgtcgta aagaaggaaa
    10621 aaaatcagac tattcactgt attaccaatt tggaactcga attgcaattg ttgaggcaaa
    10681 ggataataaa cacagcgttc gagcaggatt acaacaagct attgaatatg gagagatttt
    10741 agatgttcca tttgtttatt cttcgaatgg tgatggcttt attgaacacg accgtatcac
    10801 gagagaagaa cgtgagctgg agttagacga attccctact cgtgaagaat tattttctcg
    10861 tatgacgaag gaaaaaggat tgacgtacga aattacagaa gctatctcaa ctccatacta
    10921 tacagacgcc ttctcaatga aaacgccacg ctattatcag caaatagcta tcaaccgtac
    10981 tattgaaaca gttgccagag gacaaaaacg agtaatgttt gtgatggcaa caggaacggg
    11041 gaaaacgttc atggcttttc aaattattca tcgccttcga aaagctggtt tggctaaacg
    11101 agttttattc ttagcggata gaaacatctt agtagaccaa acgatggctg aagactttaa
    11161 gccattcgaa aaggtaatga cgaaaattac accaaaactt ttgactgctc ctgaaaaatt
    11221 aaattctttt gaaatttatc tagggcttta tcagcaacta actggtgaag atggaactga
    11281 aacacattat caaaaatttg acaaagactt ctttgattta atcgtaattg atgaagcgca
    11341 ccgtggttca gctaaggaaa acagtaactg gcgtaagata attgattatt tcagttctgc
    11401 gacacagatt gggatgaccg ctactcctaa agaaaccaag aatgcttcca atacggaata
    11461 ctttggtgag ccaatctata cttatagttt aaaacaggga atcgaggatg gttttttggc
    11521 tccatatcgt gttatgaggg ttaatttaga tgtggatgtg gatggttatc gtccagaaac
    11581 tggaaaagtt gatgctaacg gacaattaat agaagatagg tactacagca ggaaagattt
    11641 tgataaaacc attgtcattg atgatagaac gcaaagagtt gccaagtttg tttctgatta
    11701 tatgaagcaa aacaatgcac gatttgataa aacaattgtt ttttgtgttg atattgacca
    11761 tgccgagcga atgcgtgctg cacttgtaaa agagaatcta gacttagtcc aagaagacta
    11821 tcgttatgtc atgcaagtaa ctggtgacaa cgctgaagga aaagctcaac tggataactt
    11881 tatggatgtc aattctaatt ttcccgctat tgtaacaacg tctaaattat taacgacagg
    11941 agttaatgct aaaacatgtc gtttgattgt tttagactct aatatccaat ccatgactga
    12001 atttaaacaa attattggtc gtggcacacg tctttatcct caaaagggga aagaattttt
    12061 tacgattatt gattttcgaa atgttaccaa tttgtttgct gaccctgatt ttgatggtga
    12121 gccagtgaag gtgctggaaa caggtgcgaa aacagtcagt ggttctacgc ccggtttcgt
    12181 agatgaggaa ggtgacccag tagaaaaata tatcgttaca gacaagcagg ttaccattct
    12241 taattctact gttcaagtat tggatgaaaa cgggaaactg attaccgaaa gcctgaccga
    12301 ctacactcgg aagaatatct taggtagcta cgccactttg aacgatttta tcacagtttg
    12361 gcatacggcg gataaaaaga agcttatctt agacgaactt tataaaaaag gagtttatct
    12421 agatgctatt cgagagtcgg agggaatatc agaacaagaa atcgatgatt ttgatttact
    12481 cctaaaactt gcctatggtc aaaaagaatt aaccaaaacg gaacgtatca ataaactcaa
    12541 acaaagcgga tatttatata aatatagtga ggaagcgcgt gctgttttgg aaattttact
    12601 gaacaaatac atggataaag gtattggaga actcgaaagc attgaaacat taaaacttcc
    12661 agaatttcag atatatggtg gaaccttcaa aatcatcaat acttattttg gagataaaaa
    12721 acgatattta caagcaatta aagaattgga gcaagagcta tttacagtag cttaatgaaa
    12781 ggaaagtatg tcaattacat catttgtaaa aagaattcaa gatatcactc gaaacgatgc
    12841 tggtgttaat ggtgatgctc aacgtattga gcaaatgtct tggttattat tcttaaaaat
    12901 ttatgatagc cgtgaaatgg tttgggaatt agaagaagac gagtatgagt caattatccc
    12961 agaggaatta aaatggcgaa attgggctca tgctcaaaat ggggaacggg tattgacagg
    13021 cgatgaatta cttgattttg tcaataacaa gttattcaaa gagttgaaag agcttgaaat
    13081 aacttcaaat atgcctattc gaaaaacgat tgttaaatca gcttttgaag atgcgaacaa
    13141 ctatatgaaa aatggcgtct tgttacgcca agtcatcaat gttattgatg aagttgattt
    13201 caatagccct gaagatcgtc attcgtttaa tgatatttac gaaaaaattc ttaaagatat
    13261 tcaaaatgct gggaactcag gagaatttta tacgccacgt gcagcgactg attttattgc
    13321 cgaagttctt gacccaaaac ttggagaatc aatggtagac cttgcttgcg gaacaggagg
    13381 cttcttgact tcgactctga accgtttaag tagtcaacgt aaaactagtg aagataccaa
    13441 aaaatataat acagctgttt ttggtattga aaagaaagca tttcctcatc ttttagcagt
    13501 tacaaatctg tttcttcacg aaattgatga ccctaaaatt gttcatggaa atactttgga
    13561 aaaaaatgtt cgtgaatata cggatgatga aaaatttgac attattatga tgaatccacc
    13621 ttttggaggg tcagaattag aaacaataaa aaataacttt ccagcagaat tacggagttc
    13681 tgaaacagct gatttattta tggctgtcat tatgtatcgt ttgaaagaaa atggtcgtgt
    13741 tggagttatt ttacctgatg gttttctatt tggtgaaggt gtaaaaactc gcttgaaaca
    13801 aaaactggta gatgagttca acttgcatac gattattagg ttgcctcata gtgtctttgc
    13861 accgtataca ggaatccata cgaacattct tttctttgat aaaacaaaga aaacagaaga
    13921 aacttggttt tatcgtttag atatgccaga tggttataaa aatttctcga aaactaagcc
    13981 gatgaagtca gaacacttca atcctgttcg tgactggtgg gaaaatcgtg aagagattct
    14041 ggaaggtaag ttctacaaat ctaaatcatt tacacctagt gaattggctg agttgaatta
    14101 taatttagac cagtgtggtt ttccaaaaga ggaagaggaa atcttaaatc cctttgagtt
    14161 gattcagaat tatcaagcgg aaagagcaac tttaaatcat aagattgata atgtattagc
    14221 tgatattttg cagttgttgg aggacaaata atgacaccag aacaacttaa agcaagtatt
    14281 ctccaaagag cgatggaagg gaaattagtg ccgcaaaatc ccaatgacga acctgcaagt
    14341 gaattattaa agagaattaa agctgaaaaa gaaaaactta tcagtgaagg aaaaatcaaa
    14401 cgagataaaa aggaaactga gatatttcgt ggtgatgatg
//
LOCUS       DBEJAU010000050        14156 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC323 isolate 683620
            SAMN38261939-rid24807223.denovo.050, whole genome shotgun sequence.
ACCESSION   DBEJAU010000050 DBEJAU010000000
VERSION     DBEJAU010000050.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261939
            Sequence Read Archive: SRR26833919
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 14156)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14156)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576303.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576303.1
            Genome Coverage       :: 154x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/19/2025 01:05:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,121
            CDSs (total)                      :: 2,078
            Genes (coding)                    :: 1,943
            CDSs (with protein)               :: 1,943
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 36
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 72 of 135
            Pseudo Genes (incomplete)         :: 63 of 135
            Pseudo Genes (internal stop)      :: 51 of 135
            Pseudo Genes (multiple problems)  :: 46 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14156
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261939-rid24807223.denovo.050"
                     /strain="GPSC323"
                     /isolate="683620"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            382..1458
                     /locus_tag="ACL29Z_001712"
     CDS             382..1458
                     /locus_tag="ACL29Z_001712"
                     /EC_number="1.2.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000542485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004073 - aspartate-semialdehyde
                     dehydrogenase activity [Evidence IEA];
                     GO_function: GO:0016620 - oxidoreductase activity, acting
                     on the aldehyde or oxo group of donors, NAD or NADP as
                     acceptor [Evidence IEA];
                     GO_function: GO:0051287 - NAD binding [Evidence IEA];
                     GO_process: GO:0008652 - amino acid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate-semialdehyde dehydrogenase"
                     /protein_id="HGR0069981.1"
                     /translation="MGYTVAVVGATGAVGAQMIKMLEESTLPIDKIRYLASARSAGKS
                     LKFKDQDITIEETTETAFEGVDIALFSAGSSTSAKYAPYAVKAGVVVVDNTSYFRQNP
                     DVPLVVPEVNAHALDAHNGIIACPNCSTIQMMVALEPVRQKWGLDRIIVSTYQAVSGA
                     GMGAILETQRELREVLNDGVKPCDLHAEILPSGGDKKHYPIAFNALPQIDVFTDNDYT
                     YEEMKMTKETKKIMEDDSIAVSATCVRIPVLSAHSESVYIETKEVAPIEEVKAAIAAF
                     PGAVLEDDVAHQIYPQAINAVGSRDTFVGRIRKDLDAEKGIHMWVVSDNLLKGAAWNS
                     VQIAETLHERGLVRPTAELKFELK"
     gene            1514..2449
                     /gene="dapA"
                     /locus_tag="ACL29Z_001713"
     CDS             1514..2449
                     /gene="dapA"
                     /locus_tag="ACL29Z_001713"
                     /EC_number="4.3.3.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002935444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008840 - 4-hydroxy-tetrahydrodipicolinate
                     synthase activity [Evidence IEA];
                     GO_process: GO:0009089 - lysine biosynthetic process via
                     diaminopimelate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxy-tetrahydrodipicolinate synthase"
                     /protein_id="HGR0069982.1"
                     /translation="MSYQDLKECKIITAFITPFHEDGSINFDAIPALIEHLLAHHTDG
                     ILLAGTTAESPTLTHDEELELFAAVQKVVNGRVPLIAGVGTNDTRDSIEFVKEVAEFG
                     GFAAGLAIVPYYNKPSQEGMYQHFKTIADASDLPIIIYNIPGRVVVELTPETMLRLAD
                     HPNIIGVKECTSLANMAYLIEHKPEEFLIYTGEDGDAFHAMNLGADGVISVASHTNGD
                     EMHEMFTAIAESDMKKAAAIQRKFIPKVNALFSYPSPAPVKAILNYMGFEAGPTRLPL
                     VPAPEEDAKRIIKVVVDGDYEATKATVTGVLRPDY"
     gene            complement(2496..3869)
                     /gene="mnmE"
                     /locus_tag="ACL29Z_001714"
     CDS             complement(2496..3869)
                     /gene="mnmE"
                     /locus_tag="ACL29Z_001714"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002906470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_process: GO:0006400 - tRNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA uridine-5-carboxymethylaminomethyl(34)
                     synthesis GTPase MnmE"
                     /protein_id="HGR0069983.1"
                     /translation="MITREFDTIAAISTPLGEGAIGIVRLSGTDSFAIAQKIFKGKDL
                     NKVASHTLNYGHIIDPLTGKVMDEVMVGAMKSPKTFTREDIIEINTHGGIAVTNEILQ
                     LAIREGARLAEPGEFTKRAFLNGRVDLTQAEAVMDIIRAKTDKAMNIAVKQLDGSLSD
                     LINNTRQEILNTLAQVEVNIDYPEYDDVEEATTAVVREKTMEFEQLLTNLLRTARRGK
                     ILREGISTAIIGRPNVGKSSLLNNLLREDKAIVTDIAGTTRDVIEEYVNINGVPLKLI
                     DTAGIRETDDIVEQIGVERSKKALKEADLVLLVLNASEPLTAQDRQLLEISQDTNRII
                     LLNKTDLPETIETSKLPEDVIRISVLKNQNIDKIEERINNLFFENAGLVEQDATYLSN
                     ARHISLIEKAVESLQAVNQGLELGMPVDLLQVDLTRTWEILGEITGDAAPDELITQLF
                     SQFCLGK"
     gene            complement(4006..4188)
                     /locus_tag="ACL29Z_001715"
     CDS             complement(4006..4188)
                     /locus_tag="ACL29Z_001715"
                     /EC_number="5.3.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005589823.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-oxalocrotonate tautomerase"
                     /protein_id="HGR0069984.1"
                     /translation="MPFVRIDLFEGRTLEQKKALAKEVTEAVVRNTGAPQSAVHVIIN
                     DMPEGTYFPQGEMRTK"
     gene            4311..4901
                     /locus_tag="ACL29Z_001716"
     CDS             4311..4901
                     /locus_tag="ACL29Z_001716"
                     /EC_number="2.7.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000068157.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004797 - thymidine kinase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="thymidine kinase"
                     /protein_id="HGR0069985.1"
                     /translation="MAQLYYRYGTMNSGKTIEILKVAYNYEEQGKGVVIMTSALDTRD
                     GVGYVSSRIGMKRPALAIEETTDIFGYIRGLPEKPYCVLVDEAQFLKRHHVYDLARVV
                     DELDIPVMAFGLKNDFRNELFEGSKYLLLLADKIDEIKTICQYCKKKATMVLRTQDGL
                     PVYDGEQIQIGGNETYISVCRKHYFAPEINKENEEK"
     gene            4898..5977
                     /gene="prfA"
                     /locus_tag="ACL29Z_001717"
     CDS             4898..5977
                     /gene="prfA"
                     /locus_tag="ACL29Z_001717"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002262255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003747 - translation release factor
                     activity [Evidence IEA];
                     GO_process: GO:0006415 - translational termination
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 1"
                     /protein_id="HGR0069986.1"
                     /translation="MNIYDQLQAVEDRYEELGELLSDPDVVSDTKRFMELSKEEASNR
                     DTVIAYREYKQVLQNIVDAEEMIKESGGDADLEELAKQELKDAKAEKEEYEEKLKILL
                     LPKDPNDDKNIILEIRGAAGGDEAALFAGDLLTMYQKYAEAQGWRFEVMEASMNGVGG
                     FKEVVAMVSGQSVYSKLKYESGAHRVQRVPVTESQGRVHTSTATVLVMPEVEEVEYDI
                     DPKDLRVDIYHASGAGGQNVNKVATAVRIVHLPTNIKVEMQEERTQQKNREKAMKIIR
                     ARVADHFAQIAQDEQDAERKSTIGTGDRSERIRTYNFPQNRVTDHRIGLTLQKLDTIL
                     SGKLDEVVDALVLYDQTQKLEELNK"
     gene            5977..6816
                     /gene="prmC"
                     /locus_tag="ACL29Z_001718"
     CDS             5977..6816
                     /gene="prmC"
                     /locus_tag="ACL29Z_001718"
                     /EC_number="2.1.1.297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000761890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008757 - S-adenosylmethionine-dependent
                     methyltransferase activity [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA];
                     GO_process: GO:0018364 - peptidyl-glutamine methylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor N(5)-glutamine
                     methyltransferase"
                     /protein_id="HGR0069987.1"
                     /translation="MKLAQLFSNFEEELIRQGEEAESLSFVYRSLKNLSFTDFIFALQ
                     QEVTTEEEKQFVEDIYQQLAAHKPAQYIIGQADFYGMHLKVDERVLIPRPETEELVEL
                     ILTENLETNLSVLDIGTGSGAIALALAKNRPDWSVTAADVSQEALELASENASDQNLN
                     IFFKKSDCFAEIFEKYDIIVSNPPYISREDESEVGLNVLHSEPHLALFADEDGLAIYC
                     RIAEDAKDYLKDGGKIYLEIGYKQGQSVPELFRKHLPEKRVRTLKDQFGQDRMVVVDD
                     GQD"
     gene            6803..7402
                     /locus_tag="ACL29Z_001719"
     CDS             6803..7402
                     /locus_tag="ACL29Z_001719"
                     /EC_number="2.7.7.87"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809176.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003725 - double-stranded RNA binding
                     [Evidence IEA];
                     GO_function: GO:0061710 - L-threonylcarbamoyladenylate
                     synthase [Evidence IEA];
                     GO_process: GO:0006400 - tRNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="L-threonylcarbamoyladenylate synthase"
                     /protein_id="HGR0069988.1"
                     /translation="MDRIRQELENGGAVILPTETVYGLFAKALDEKAVDHVYQLKRRP
                     RDKALNLNVASLEDILHFSKNQPAYLQKLVETFLPGPLTIILEANDRVPYWVNSDLAT
                     IGFRMPSHPITLDLIRETGPLIGPSANISGQASGVTFEQILKDFDQEVLGLEDDAFLT
                     GQDSTIVDLSGDKVKILRQGAIKREDILARLPEISFEEA"
     gene            7404..7835
                     /locus_tag="ACL29Z_001720"
     CDS             7404..7835
                     /locus_tag="ACL29Z_001720"
                     /EC_number="2.3.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000942930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0016746 - acyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HGR0069989.1"
                     /translation="MLRDLQETDVKAICDINQEALGYTFSPEETASQLARLSQDSHHF
                     LLGYEDAANHVLLGYVHAEVYESLYSKAGFNILALAVSPQAQGQGIGKSLLQGLEQEA
                     KRCGYGFIRLNSANHRLGAHAFYEKVGYTCDKVQKRFIRIF"
     gene            7896..9152
                     /gene="glyA"
                     /locus_tag="ACL29Z_001721"
     CDS             7896..9152
                     /gene="glyA"
                     /locus_tag="ACL29Z_001721"
                     /EC_number="2.1.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863152.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004372 - glycine hydroxymethyltransferase
                     activity [Evidence IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA];
                     GO_function: GO:0070905 - serine binding [Evidence IEA];
                     GO_process: GO:0019264 - glycine biosynthetic process from
                     serine [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="serine hydroxymethyltransferase"
                     /protein_id="HGR0069990.1"
                     /translation="MIFDKDDFKAYDADLWNAIAKEEERQQNNIELIASENVVSKAVM
                     AAQGSILTNKYAEGYPGRRYYGGTDVVDVVETLAIERAKEIFGAKFANVQPHSGSQAN
                     CAAYMSLIEPGDTVMGMDLASGGHLTHGAPVSFSGQTYNFVSYSVDPETELLDFDAIL
                     KQAQEVKPKLIVAGASAYSQIIDFSKFREIADAVGAKLMVDMAHIAGLVAAGLHPSPV
                     PYAHITTTTTHKTLRGPRGGLILTNDEELAKKINSAIFPGIQGGPLEHVVAAKAVSFK
                     EVLDPAFKEYAANVIKNSKAMADVFLQDPDFRIISGGTENHLFLVDVTKVVENGKVAQ
                     NLLDEVNITLNKNSIPYESLSPFKTSGIRIGAAAITARGFGEEESRKVAEFIIKTLKN
                     SENEAVLEEVRSAVKELTDAFLLYED"
     gene            9160..10134
                     /locus_tag="ACL29Z_001722"
     CDS             9160..10134
                     /locus_tag="ACL29Z_001722"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006153495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoid-associated protein"
                     /protein_id="HGR0069991.1"
                     /translation="MDIYIKKAIIHQFSPDDTELFLADKFLNITPKIEEYLRKKIEHV
                     YSDEAKTGIFEEENPFFNHITDDLLETSVTLANLWKEEFSISENLKTNDLIFVQFSKE
                     GVEHFAFLRIALRETLTHLGGEVDNPIKLTQNNLPGFGTGADEALVANLQSRKYHLIE
                     KRIKYNGTFLNYFSDNLLAVAPKISPKKSIKELEKTAQRIAESFNTDDFQFQSKVKSA
                     IFNNLEESNELSPEKLANDLFDNNLTARLSFIDQVKEAVPEPVQFDEIDASRQLKKFE
                     NQKLSLSNGIELIVPNNVYQDADSVEFIQNENGTYSILIKNIEDIQSK"
     gene            10134..10748
                     /gene="pmp23"
                     /locus_tag="ACL29Z_001723"
     CDS             10134..10748
                     /gene="pmp23"
                     /locus_tag="ACL29Z_001723"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000476388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall hydrolase Pmp23"
                     /protein_id="HGR0069992.1"
                     /translation="MFKRIRRVLVLAVFLFAGYKAYRVHQDVKQVMTYQPMVREILSE
                     KDTPANEELVLAMIYTETKGKEGDVMQSSESASGSTNTINDNASSIRQGIQTLTGNLY
                     LAQKKGVDIWTAVQAYNFGPAYIDFIAQNGKENTLALAKQYSRETVAPLLGNTTGKTY
                     SYIHPISIFHGAELYVNGGNYYYSRQVRLNLYIIKCFTLFSTSG"
     gene            10822..11796
                     /locus_tag="ACL29Z_001724"
     CDS             10822..11796
                     /locus_tag="ACL29Z_001724"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001227757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1002 domain-containing protein"
                     /protein_id="HGR0069993.1"
                     /translation="MRKKLFLTSAAVLWAVTAMNSVHAATDVQKVIDETYVQPEYVLG
                     SSLSEDQKNQTLKKLGYNASTDTKELKTMTPDVYSKIMNVANDSSLQLYSSAKIQKLG
                     DKSPLEVKIETPENITKVTQDMYRNAAVTLGVEHAKITVAAPIPVTGESALAGIYYSL
                     EANGAKVPQANKDLAQEELKALSDINAENKDKSGYDANKLNVALADIKSGLAKAKESK
                     GNLTEEDVRKIVEDTLKNYKLDQVITGNQINIIINFALNLSKSDILSNADFTKTLNDL
                     KQSIVSQAGDSFKNINLNFDADKALEDGGNFLSSLWQAIANFFKSFGS"
     gene            11870..13492
                     /gene="rlmD"
                     /locus_tag="ACL29Z_001725"
     CDS             11870..13492
                     /gene="rlmD"
                     /locus_tag="ACL29Z_001725"
                     /EC_number="2.1.1.190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000914584.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008649 - rRNA methyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (uracil(1939)-C(5))-methyltransferase
                     RlmD"
                     /protein_id="HGR0069994.1"
                     /translation="MLKKNDIVEVEIVDLTHEGAGVAKVDGLVFFVENALPSEKILIR
                     VLKVNKKIGFGKVEEYLVQSPHRNQDLDLAYLRSGIADLGHLAYPEQLKFKTKQVKDS
                     LYKIAGIADVEVAETLGMEHPVKYRNKAQVPVRRVNGVLETGFFRKNSHNLMPLEDFF
                     IQDPVIDQVVVALRDLLRRFDLKPYDEKEQSGLIRNLVVRRGHYSGQIMVVLVTTRPK
                     VFRVDQLIEQVIKQFPEIVSVMQNINDQNTNAIFGKEWRTLYGQDYITDQMLGNDFQI
                     AGPAFYQVNTEMAEKLYQTAIDFAELKKDDVVIDAYSGIGTIGLSVAKHVKEVYGVEL
                     IPEAVENSKKNAQLNNISNAHYVCDTAENAMKNWLKDGIQPTVILVDPPRKGLTESFI
                     KASAQTGADRIAYISCNVATMARDIKLYQELGYELKKVQPVDLFPQTHHVETVALLSK
                     LDVDKHISVEIELDLTSAESKATYAQIKEYVWNKFELKVSTLYIAQIKKKCGIELREH
                     YNKSKKDKQIIPQCTPEKEEAIMDALRHFKMI"
     gene            13706..13984
                     /locus_tag="ACL29Z_001726"
     CDS             13706..13984
                     /locus_tag="ACL29Z_001726"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000710796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0069995.1"
                     /translation="MKKDKEVYDKVCEYLSPHLNKDMEVLELACWFRVITVIEANSYV
                     NIRSSRLLPKFKTQKINSWCAAYNIHFNNGYCKQHTNEFKDSLKSLIL"
BASE COUNT         4337 a         2726 c         3060 g         4033 t
ORIGIN      
        1 ttttgaggtt gtagatgaaa ctgacgaagt cagtaaccat acatacggca aggcgacgct
       61 gacgaagttt gaagagattt tcgaagagta taaagagttt cgtctgttga caaaagtcat
      121 tctctttagt agaatagtag atgcgatgag tcgataggta gtcttcgggc tactattgag
      181 cataaggagg tcataacgca ggagcggacc ttgatgagtt gtgtgaacct gctcatcaca
      241 tgaagatgcc tcttagtccc tagtctagcg actgggattt ttattttcca aaaaatgatg
      301 aaaaagcttt gcaattcatg gaaaaagtag tataatactt ctattataga aatttttaga
      361 aaattccgaa agaggttatt tatgggatat acagttgctg tagtcggcgc gacaggtgct
      421 gtcggtgctc agatgataaa aatgttggaa gaatcaacac ttccaatcga taaaatccgt
      481 taccttgctt ctgcacgttc agcaggtaag tcattgaaat ttaaagatca agatattaca
      541 attgaagaaa cgactgaaac agcttttgaa ggagttgata ttgctctctt ttcagcaggt
      601 agttctacat cagctaagta tgcaccatac gcagtaaaag ctggcgtggt agtagtagat
      661 aatacatctt atttccgtca aaatccagat gttcctttgg ttgttccaga ggtcaatgct
      721 catgcacttg atgctcacaa cggaatcatt gcctgcccta attgttcaac aatccaaatg
      781 atggtggctc ttgagccggt tcgccaaaaa tggggcttgg accgtatcat tgtttcaact
      841 tatcaagccg tttcaggtgc tggtatggga gcaattcttg agacacaacg tgaacttcgt
      901 gaagtcttga atgatggtgt gaaaccatgt gatttgcatg cggaaatttt gccttcaggt
      961 ggtgacaaga aacattatcc tatcgccttt aacgctcttc cacaaattga tgttttcact
     1021 gataatgatt acacgtacga agagatgaag atgaccaagg aaactaagaa aattatggaa
     1081 gatgatagca ttgcagtatc tgcaacatgt gtgcgtattc cagtcttgtc agctcactct
     1141 gagtctgttt atatcgaaac aaaagaagtg gctccaatcg aagaagtaaa agcagctatc
     1201 gcagccttcc caggtgctgt tcttgaagat gatgtagctc atcaaatcta tcctcaagct
     1261 atcaatgcag ttggttcgcg tgataccttt gttggtcgta tccgtaaaga cttggatgca
     1321 gaaaaaggaa ttcacatgtg ggttgtttca gataaccttc tcaaaggtgc tgcttggaac
     1381 tcagttcaga ttgctgaaac tcttcatgaa cgtggattgg ttcgtccaac agccgaattg
     1441 aaatttgaat taaaatagtc atatcgttta ggagttcaga tgaactcctt ctttgaaata
     1501 gagaggtgtt ttcgtgtctt atcaagattt aaaagaatgt aaaatcatta cagcctttat
     1561 tacccccttc catgaggatg gttccattaa ctttgatgct attccagcct tgattgagca
     1621 tttattggcc catcatacgg atggaattct tctcgcagga acgactgctg agagtccaac
     1681 tttgacccac gatgaggagt tggagttgtt tgcggctgta caaaaggttg tcaatggacg
     1741 cgttcctttg attgcgggtg taggtactaa tgatacgcgt gattctattg agtttgtcaa
     1801 agaagtagcg gaatttggtg gtttcgcagc tgggcttgct attgttcctt actacaacaa
     1861 accttctcaa gaagggatgt atcagcactt taagactatt gcagatgctt ctgacctacc
     1921 aattattatc tataacattc cagggcgtgt agttgtcgaa ttgactccag aaaccatgct
     1981 tcgcttggct gaccatccaa atattatcgg tgtcaaagaa tgtactagct tggctaatat
     2041 ggcttacttg attgagcaca agcctgaaga gttcttgatt tatacaggtg aggatggaga
     2101 tgctttccat gccatgaacc ttggggcgga tggggttatt tctgttgcct ctcatacaaa
     2161 tggggatgaa atgcacgaga tgtttactgc cattgcagaa agcgatatga agaaagccgc
     2221 agcaattcag cgtaaattca ttcctaaggt taatgctctc ttctcttatc caagtcctgc
     2281 tccagttaag gcaattctta actatatggg atttgaagct ggacccactc gtctacctct
     2341 tgttccagca ccagaagaag atgccaaacg cattatcaag gttgtcgtag atggcgacta
     2401 cgaagcaact aaggcaactg taacaggggt cttaagacca gattactaat aaagacaata
     2461 aaatccatga ccgaatgaag gatcatggat ttttcttatt ttcctaaaca gaattggcta
     2521 aagagttggg taataagttc atctggagca gcatccccag tgatttctcc gaggatttcc
     2581 caagtacgag tcaagtcaac ttgaagcaaa tcaactggca tccccagctc aagaccttga
     2641 ttaacggctt gtaggctttc aactgctttt tcaatcaggg aaatgtgacg ggcgtttgac
     2701 aagtaggtag catcttgctc gaccaagcca gcattttcaa agaagaggtt gttgattcgc
     2761 tcttcaatct tgtcgatgtt ttggttttta aggactgaaa tacggataac gtcttcaggt
     2821 agtttcgaag tttcaatcgt ttctggcagg tcggttttat taagtagaat aatgcgattg
     2881 gtatcttggc taatttcaag aagttgtctg tcttgcgcag tcagtggttc actggcattt
     2941 agcactagta gaaccaagtc ggcttccttg agggcttttt tcgaacgctc aacaccgatt
     3001 tgttccacta tgtcatctgt ttcacgaata ccggctgtat caatcaattt gagaggtaca
     3061 ccattgatgt tgacgtactc ttcgatgaca tctcgtgttg tcccagcgat atctgttacg
     3121 atagccttgt cctcacgcaa gaggttgttg agaaggctgg atttcccaac gttgggacgt
     3181 ccgatgatag ctgttgaaat tccttcacga aggattttgc cgcgacgggc tgttctaaga
     3241 agattggtta gcaattgctc aaactccata gtcttctcac ggacaacggc agtagtagct
     3301 tcctcaacat catcatattc aggatagtcg atattgacct caacttgggc aagtgtattg
     3361 aggatttctt gacgggtatt gttaatgagg tcagaaaggg agccgtctaa ttgtttgacc
     3421 gcaatgttca tggccttgtc agtcttggca cggatgatat ccatcacagc ctctgcctgt
     3481 gtcaagtcta cgcgaccgtt taaaaaagca cgtttggtaa attcaccagg ttctgccaac
     3541 cgagcccctt cacgaatagc tagctggaga atttcattgg tcaccgcaat cccaccgtgg
     3601 gtgttaatct cgataatatc ctcacgagtg aaggtctttg gagacttcat agccccaacc
     3661 ataacctcgt ccatgacttt accagtcaga ggatcaataa tgtgaccgta gttgagagtg
     3721 tggctggcaa ccttgttcaa gtcttttcct ttaaaaatct tttgcgcaat agcaaaactg
     3781 tctgttccgc tcaggcggac aataccaata gccccttcac ctagtggagt agagatagca
     3841 gcgatggtat caaattcacg tgtaatcata atgtttcctt taattaatag ctcttttctt
     3901 ggaaattctc caagtttctt ttcaaattgt aacaaattta ggatatttct tcaatgaatg
     3961 ctacttggag attgaaaaag cctaagcaat tctgcttaag ctagcttatt tagtacgcat
     4021 ttccccttgt gggaagtaag ttccttctgg catgtcgttg atgatgacat ggacagcaga
     4081 ttgaggggct ccagtgttgc ggacaactgc ttccgttact tccttagcaa gagctttctt
     4141 ttgctcgagc gtgcgtcctt caaataaatc gatgcgtaca aatggcataa tagcttcctc
     4201 cactagtttt gatttcttcc attttaccac attttgccgt ttaaagctta agaaaattat
     4261 gatatactag aatgtagcaa aaatttagaa atggacgtga agcaagaaac atggcacagt
     4321 tgtactatcg ttatgggacc atgaactctg gaaagacaat cgagattctc aaggtggcct
     4381 ataactatga ggagcaagga aaaggtgttg tgattatgac ttcagctctg gatacgcgtg
     4441 acggtgttgg ctatgtgtcg agtcgaattg gcatgaaacg ccctgccctt gcgattgagg
     4501 aaacaacgga tatctttggc tatatccgag gcctaccaga aaaaccttac tgtgtgttgg
     4561 tcgatgaagc ccagtttctc aaacgccacc atgtttatga cctagctcgt gttgtggacg
     4621 agttagacat acccgtcatg gcttttggct tgaaaaatga ctttcgcaat gaattgttcg
     4681 aaggttccaa atatctcttg cttttagcag acaagattga cgaaatcaag accatctgtc
     4741 agtattgcaa gaaaaaggcg accatggtgt tgcgaacaca ggatggactg cccgtttacg
     4801 atggagaaca gatccaaatt ggtggtaatg aaacctatat ctcggtttgc cgtaaacatt
     4861 attttgcccc tgaaatcaat aaggagaatg aagaaaaatg aacatctatg atcaactaca
     4921 agctgtagaa gaccgttatg aagaactagg agaattgctg agtgaccctg atgtcgtttc
     4981 agacaccaag cgttttatgg agctttcaaa agaagaagct tccaatcgtg acaccgtaat
     5041 agcctaccgt gagtataaac aagtccttca aaatatcgtc gatgccgaag agatgattaa
     5101 ggaatcaggc ggagatgcgg acttggaaga attggccaag caagaactca aagatgccaa
     5161 ggctgaaaaa gaagaatatg aagaaaaact gaaaattttg ctccttccaa aggatccaaa
     5221 cgatgacaag aatatcatcc ttgaaatccg tggagcagct ggtggagacg aagcggcact
     5281 tttcgctgga gatttgctaa ctatgtacca aaagtatgcg gaagcccaag gttggcgctt
     5341 tgaagtcatg gaagcctcta tgaatggtgt cggtggtttt aaagaagtgg ttgctatggt
     5401 ttcaggtcag tctgtatact ctaagcttaa gtatgaatca ggtgcccacc gtgtgcaacg
     5461 tgttcctgtg acagaaagcc aaggccgtgt tcatacttcg acagcgacag ttcttgttat
     5521 gccagaagtt gaagaggttg aatacgacat tgatccaaaa gaccttcgtg tcgacatcta
     5581 tcacgcctct ggtgctggtg gacagaacgt caataaggtt gcgactgccg ttcgtatcgt
     5641 tcacttgcca accaatatca aggttgagat gcaggaagaa cgtacccagc agaagaaccg
     5701 cgagaaggct atgaagatta tccgtgcacg cgtcgctgac cactttgctc agattgctca
     5761 ggatgaacaa gacgctgagc gtaagtcgac aatcggtact ggtgaccgtt cagaacggat
     5821 ccgaacttat aacttcccac aaaaccgtgt cacagaccac cgtatcggct tgaccctcca
     5881 aaaactagat acgattttgt ctggtaaatt ggacgaagtt gtggatgcct tggtgcttta
     5941 tgaccaaaca caaaaactag aagaattaaa caaataatga aattagctca attattttca
     6001 aattttgaag aagagttgat aagacaagga gaggaagcgg aaagcctctc ttttgtctat
     6061 cgtagtctga aaaatctatc ttttacagac tttatttttg ccctccagca ggaggtgaca
     6121 acagaggaag aaaaacaatt tgtagaagat atttaccagc aactagcagc tcacaagcca
     6181 gctcagtaca tcattggaca ggcagatttt tatggaatgc atttaaaggt ggatgaacgg
     6241 gttttgattc ctcgtccaga aacagaggag ttagtggagc ttattctaac tgaaaatctt
     6301 gagacgaatc tctcagttct ggatattgga acaggtagtg gagctattgc tctcgctcta
     6361 gcaaaaaata gaccagattg gtcagtgaca gcagcagatg tttctcaaga ggccttagag
     6421 cttgcatcag agaatgctag cgatcaaaat cttaatatat tttttaaaaa atctgattgt
     6481 tttgcagaaa tttttgaaaa atatgatata attgtatcca atccacccta tatctctcgt
     6541 gaagatgagt cagaggtagg cttgaatgtt ttgcattcgg agcctcatct agctctcttt
     6601 gcagacgagg atggcctagc tatttactgt agaattgcgg aagatgcaaa agactatctc
     6661 aaggatggtg gtaagattta ccttgaaatt ggatacaagc aaggtcaaag tgttcccgaa
     6721 ctttttagga aacatcttcc tgaaaaaaga gttcgaacac tcaaggacca atttggtcaa
     6781 gataggatgg tcgtggttga tgatggacag gattagacaa gagttggaaa atggtggagc
     6841 tgtcattctg cctacagaga cggtttatgg tctttttgcc aaggccttag acgaaaaagc
     6901 agttgaccat gtttaccagc tcaaacgtcg tcctagagac aaggcgctca atctcaatgt
     6961 tgcctcttta gaggatatct tgcacttttc taagaatcag ccagcttatc tacaaaaact
     7021 tgtagagacc tttttgccag gtcccttgac cattattctc gaagccaatg accgagttcc
     7081 ctattgggta aattctgacc ttgcaactat tggatttcgg atgcccagtc accctatcac
     7141 actggattta attcgagaga caggtccctt gattgggccg tctgccaata tctcaggtca
     7201 ggcaagtggt gtaacctttg aacaaattct gaaggatttt gaccaagagg ttctgggtct
     7261 ggaagacgat gcttttctaa ctggacagga ttcaactatt gtggatttgt ctggagacaa
     7321 ggtgaaaatc ttacgccaag gcgcaattaa acgagaagat attcttgctc ggttgccaga
     7381 gatttctttt gaggaggctt gaaatgctaa gagatttgca agaaacagat gtgaaagcga
     7441 tatgtgacat caaccaagag gctttgggtt atacttttag tccagaggaa acggctagcc
     7501 aactagctag actgtctcag gattcccatc atttcctact tggctatgag gatgcagcta
     7561 atcatgtctt acttggatat gtccacgctg aagtttacga atcactctat tccaaagcag
     7621 gatttaatat cttagcttta gcagtttcac ctcaagcgca aggtcaaggt atcggtaaaa
     7681 gtttactaca agggttggaa caagaagcca aaagatgtgg ttatgggttt atccgcttaa
     7741 attctgccaa tcatcgtctg ggtgctcatg cattttatga aaaagttggt tatacttgtg
     7801 ataaagtgca gaaacggttt attcgcatct tttagtttat tttcttattg taaaatcaaa
     7861 ctaatggact agtcacacaa taaaggagaa gacctatgat ttttgacaaa gatgatttta
     7921 aagcatatga tgctgatctc tggaatgcta ttgctaaaga agaagaacgc caacaaaata
     7981 atatcgagtt gattgcttcg gaaaacgtag tttccaaggc tgttatggca gctcaagggt
     8041 ctatcttgac aaacaaatat gccgagggtt acccaggacg ccgttattat ggtggaactg
     8101 atgtagtaga cgttgtagag actcttgcta ttgaacgcgc aaaagaaatt ttcggtgcta
     8161 aatttgccaa tgtccaacca cattcaggaa gccaagctaa ctgtgcggct tacatgtcct
     8221 tgattgagcc aggtgatacg gttatgggaa tggatttggc atcaggtggt catttgactc
     8281 atggggctcc tgttagcttc tctggtcaaa cctacaactt tgtttcttat agtgtggatc
     8341 ctgaaacgga actcttagac tttgatgcta tcttgaaaca agcccaagaa gtaaaaccaa
     8401 aactgattgt agctggtgct tcagcctatt ctcaaattat cgatttttca aaattccgtg
     8461 aaattgcaga tgctgttggg gcgaagctca tggtggacat ggcccatatc gctggtttgg
     8521 ttgcggctgg ccttcatcca agcccagttc catacgctca tatcacaaca acaacgaccc
     8581 acaaaaccct tcgtggtcct cgtggtggtt tgattttgac caatgacgaa gaacttgcta
     8641 aaaaaatcaa ttcagctatt ttcccaggta ttcagggcgg tcctttagag catgttgtgg
     8701 cggctaaggc agtttccttc aaagaagttt tggatccagc cttcaaggaa tatgctgcca
     8761 atgtaattaa gaacagcaag gctatggcag atgtcttctt gcaagaccct gatttccgta
     8821 ttatttcagg tggaactgaa aaccatctct tccttgttga tgtgactaaa gttgtagaaa
     8881 acggcaaagt tgctcaaaac ttgttggatg aagtcaatat taccttaaat aaaaactcaa
     8941 tcccttacga aagcttgtca ccattcaaga caagtgggat tcgtatcgga gcagcagcca
     9001 ttactgcacg tggatttggt gaagaagaaa gtcgcaaagt ggctgaattc atcattaaaa
     9061 cccttaagaa ttcagaaaat gaggctgtat tagaagaagt gagaagtgca gtcaaagaat
     9121 tgacagatgc cttcctacta tacgaggact aaaactttta tggacattta tattaagaaa
     9181 gccattattc accagttcag tccggatgat accgaactgt tcttagcaga taagtttctc
     9241 aatattactc caaaaatcga agaatacctg cgtaaaaaaa ttgaacatgt gtattcagat
     9301 gaagccaaga ctgggatttt cgaagaagaa aatcccttct tcaatcatat tacagacgat
     9361 ttgttggaga catcagtaac gctggctaat ctctggaaag aggagtttag catttctgaa
     9421 aatctcaaga ccaatgactt gatttttgtt caattttcta aagaaggtgt agaacatttc
     9481 gctttcttgc gaattgccct gcgggagacc ttgacccacc tcggaggaga agttgataat
     9541 ccaatcaagc taactcagaa taacctgcct ggatttggaa cgggtgctga cgaggccttg
     9601 gtggccaatc ttcagagtcg caagtatcac ctgattgaaa aacgaatcaa gtacaacggg
     9661 acttttttga actatttttc agataatctt cttgctgtcg ctcctaagat ttctcctaaa
     9721 aaatctatca aggaactgga aaaaacagcc cagagaattg ctgaatcttt taacacagat
     9781 gattttcaat ttcaatccaa ggtcaaatca gcgattttca acaacctaga agaaagcaat
     9841 gaattgtcac ctgagaaatt ggctaatgac ctttttgaca acaatctgac ggctcgtttg
     9901 agctttattg accaagtcaa agaagccgta ccagaacctg ttcaatttga tgaaattgat
     9961 gccagtcgcc aattaaagaa atttgaaaac caaaaactct ccttatcaaa tggaattgag
    10021 ctcatcgttc ccaataacgt ctatcaagac gccgactctg ttgagtttat ccaaaacgaa
    10081 aatggaacct actctatctt aatcaaaaat atcgaggata tccaaagtaa ataatgttta
    10141 aacgaattcg aagagtgctt gtactagcag tcttcctttt tgctggctat aaagcttacc
    10201 gcgttcatca agatgtcaaa caagtcatga cctatcaacc catggtgcga gaaatattga
    10261 gtgaaaaaga caccccagca aacgaagagc ttgtacttgc tatgatttat actgaaacaa
    10321 aaggaaaaga aggcgatgtt atgcagtcta gtgagtctgc aagtggttcc accaacacca
    10381 tcaatgataa tgcctctagc attcggcaag gcattcaaac tctgacaggc aatctctatc
    10441 tggcgcagaa gaagggtgta gatatctgga cagctgttca agcctataat tttggacctg
    10501 cctatatcga ttttatcgcc caaaatggca aggaaaatac cttggctcta gccaaacagt
    10561 actctcgtga gactgttgcc cccttgcttg gtaatacgac tggaaagact tatagttata
    10621 ttcaccccat ttccattttt cacggtgctg aactctatgt aaatggagga aactattatt
    10681 attctagaca ggtacgactt aacctttaca tcatcaaatg tttcactctc ttttcaacat
    10741 ctggctagac caggtgtttt tgttataagt tttctttaag atagatatat tactataaag
    10801 aagtaaagga ggaaattccc tatgagaaag aaactctttc tgactagtgc tgcggtcttg
    10861 tgggcagtaa cagctatgaa tagcgtccat gcagcaacag atgtgcaaaa agttatcgat
    10921 gaaacctatg tccaacctga atatgtccta ggttcctccc tatctgaaga ccaaaaaaat
    10981 caaactctta aaaaactggg ctacaatgcc tcaacagata ccaaagaact caagaccatg
    11041 acacctgatg tttattctaa aatcatgaat gtggccaatg actctagctt acagttgtat
    11101 tcatcagcca agattcaaaa gctaggtgac aaatcgccac ttgaggtcaa gattgaaaca
    11161 cctgaaaaca tcactaaggt aactcaggat atgtaccgaa atgcagccgt aactttgggt
    11221 gtggaacacg ccaaaatcac tgtagcagca cccattccag ttacaggtga gagtgctttg
    11281 gctgggatct actattcgct agaagctaat ggagccaagg tgccgcaagc caataaagat
    11341 ttggctcaag aagagctaaa ggctttgtca gatatcaatg ctgaaaacaa ggacaaatca
    11401 ggctatgatg ctaataaatt aaacgttgcc ctagctgata tcaagtcagg actcgccaaa
    11461 gctaaagaaa gcaagggaaa tctgacagaa gaagatgtcc gcaagattgt tgaagatacc
    11521 ttaaaaaatt acaaacttga tcaggttata acaggaaacc agatcaatat catcatcaat
    11581 tttgctttaa atctctccaa aagtgatatc ctcagcaatg cagacttcac taaaacctta
    11641 aatgacctta aacaaagtat cgtatcacaa gctggcgaca gttttaaaaa tatcaatctt
    11701 aactttgatg ctgataaggc gctagaagac gggggtaact tcttaagttc cctctggcaa
    11761 gccattgcca acttcttcaa gagttttggt tcttaagaaa tttcatggta taatagatgg
    11821 taaccgtaac gttgccgtct tttttgtcgg ccaatagaaa gagaagagaa tgttaaagaa
    11881 aaatgatatt gtagaagttg aaattgttga cttgacccat gaaggtgcag gagttgccaa
    11941 ggtagatggt ttggtctttt ttgtcgaaaa tgctttaccg agtgaaaaga tcctcattcg
    12001 tgtcctcaag gttaataaaa agattggttt tgggaaggtt gaagaatacc ttgtccagtc
    12061 accgcaccgt aatcaagatc tagatttagc ttatctgcgt tcaggaattg ctgatttggg
    12121 tcatcttgcc tatccagaac agctcaaatt taaaaccaag caagtcaagg acagtctcta
    12181 caagattgct ggaattgcag atgtagaagt tgctgaaacg cttggtatgg aacatccagt
    12241 caagtatcgc aataaggcgc aggtgcccgt tcgtcgagtg aatggtgtct tggaaacagg
    12301 atttttccgt aagaattcgc ataacctcat gccccttgaa gatttcttta tccaggatcc
    12361 tgtcattgac caagtcgtag tagctcttcg agacctgctc cgtcgttttg atttaaaacc
    12421 ttatgacgaa aaggaacagt ctggattgat tcggaatctt gtggtgcgtc gtggtcacta
    12481 ttcaggacaa atcatggtcg ttttggtgac aactcgtcca aaagtttttc gtgttgacca
    12541 attgattgaa caagttatca agcagttccc agagattgtg tctgtcatgc aaaatatcaa
    12601 cgaccagaat accaatgcga tttttggtaa ggagtggcgc actctttatg gtcaagacta
    12661 tattacggac cagatgttgg gaaatgactt ccaaatcgct ggcccagcct tttaccaagt
    12721 caatactgaa atggcggaga aactctatca aacagccatt gactttgcag agttaaaaaa
    12781 agatgacgtg gttattgatg cttattctgg tattggaacc attggtttat cagtcgccaa
    12841 gcatgtcaaa gaagtctacg gtgttgaact gattccagaa gcggttgaga atagtaaaaa
    12901 aaatgctcag ctgaacaata tttcaaacgc ccactatgtc tgtgacacag ctgaaaatgc
    12961 tatgaagaat tggcttaaag atgggattca accaaccgtt atcttggttg atcctccacg
    13021 caagggcttg acagaaagct ttatcaaagc aagcgcccaa acaggagccg atcgcatcgc
    13081 ctatatctcc tgcaatgtcg caaccatggc gcgtgatatc aaactctacc aagaattggg
    13141 atatgaattg aagaaagtcc agccggtgga tctatttcct caaacgcatc acgtcgagac
    13201 ggtagcactt ttgtccaaac ttgatgtcga taagcacata agtgttgaaa ttgagctgga
    13261 tttgacaagt gcggagagca aagcaacata tgctcaaatc aaagaatatg tttggaataa
    13321 atttgaatta aaagtttcga cattatatat tgcacagata aaaaagaaat gtggaataga
    13381 attacgagaa cattacaaca agtctaaaaa ggataaacaa attattccac agtgtacacc
    13441 tgaaaaagaa gaagccatca tggatgcttt gagacacttc aaaatgattt aatagaaaag
    13501 aatgacagta tatgactttc tgcatttatt acattcctac ttggtatagg aacagctatt
    13561 attcctttct tgcaaggtat caattagaaa ataggctcaa tataaagatt gataggatca
    13621 tttttatatt taaaggagcg ttgaaatgat tgataaaggc aacaaaaaat tttaggataa
    13681 atttgctaag ttgtatgccc cttttatgaa aaaagataaa gaggtttatg ataaagtttg
    13741 tgaatatctt agtcctcatt tgaataaaga tatggaggtg cttgaacttg cttgttggtt
    13801 tcgtgtcata acagttatag aggcaaatag ttatgtaaat ataaggagtt caagacttct
    13861 accaaagttt aaaactcaaa aaataaatag ttggtgtgct gcttacaata tccattttaa
    13921 taatggatat tgtaagcagc ataccaatga atttaaagat tctttaaaga gtcttatttt
    13981 gtgatgaaaa tttaatatgt aaatctcaga cgatagaaat taaaaactct atcgtctttt
    14041 ttatactcaa aattaggagg taaaaatggt aaggataaga ggtcccactt aaaacaattt
    14101 atggcaaaat aaggacggaa taacacaaca aattctctaa aacaaatcac taaatc
//
LOCUS       DBEJAU010000051        13391 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC323 isolate 683620
            SAMN38261939-rid24807223.denovo.051, whole genome shotgun sequence.
ACCESSION   DBEJAU010000051 DBEJAU010000000
VERSION     DBEJAU010000051.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261939
            Sequence Read Archive: SRR26833919
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 13391)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13391)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576303.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576303.1
            Genome Coverage       :: 154x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/19/2025 01:05:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,121
            CDSs (total)                      :: 2,078
            Genes (coding)                    :: 1,943
            CDSs (with protein)               :: 1,943
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 36
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 72 of 135
            Pseudo Genes (incomplete)         :: 63 of 135
            Pseudo Genes (internal stop)      :: 51 of 135
            Pseudo Genes (multiple problems)  :: 46 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13391
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261939-rid24807223.denovo.051"
                     /strain="GPSC323"
                     /isolate="683620"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            138..779
                     /locus_tag="ACL29Z_001727"
     CDS             138..779
                     /locus_tag="ACL29Z_001727"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004253193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0006865 - amino acid transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HGR0069996.1"
                     /translation="MSYLFEILPSLLNGASTTVQVFALVLLFSIPLGVLIAFALQVHW
                     KPLHYLINIYIWVMRGTPLLLQLIFIYYVLPSIGIRLDRLPAAIIAFVLNYAAYFAEI
                     FRGGIDTIPRGQYEAAKVLKFSPFDRVRYIILPQVTKIVLPSVFNEVMSLVKDTSLVY
                     ALGISDLILASRTAANRDASLVPMFLAGAIYLILIGIVTIISKKVEKKYSYYR"
     gene            789..1418
                     /locus_tag="ACL29Z_001728"
     CDS             789..1418
                     /locus_tag="ACL29Z_001728"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000891751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HGR0069997.1"
                     /translation="MLELRNINKVFGDKQILSNFSLSIPEKQILAIVGPSGGGKTTLL
                     RMLAGLETIDSGQIFYNGQPLELDELQKRNLLGFVFQDFQLFPHLSVLENLTLSPVKT
                     MGMKQEEAEKKASGLLEQLGLGGHAEAYPFSLSGGQKQRVALARAMMIDPEIIGYDEP
                     TSALDPELRLEVEKLILQNRELGMTQIVVTHDLQFAENIADVLLKVEPK"
     gene            1431..2267
                     /locus_tag="ACL29Z_001729"
     CDS             1431..2267
                     /locus_tag="ACL29Z_001729"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000759190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter substrate-binding
                     protein"
                     /protein_id="HGR0069998.1"
                     /translation="MKKWMLVLVSLMTALFLVACGKNSSETSGDNWSKYQSNKSITIG
                     FDSTFVPMGFAQKDGSYAGFDIDLATAVFEKYGITVNWQPIDWDLKEAELTKGTIDLI
                     WNGYSATDERREKVAFSNSYMKNEQVLVTKKSSGITTAKDMTGKTLGAQAGSSGYADF
                     EANPEILKNIVANKEANQYQTFNEALIDLKNDRIDGLLIDRVYANYYLEAEGVLNDYN
                     VFTVGLETEAFAVGARKEDTNLVKKINEAFSSLYKDGKFQEISQKWFGEDVATKEVKE
                     GQ"
     gene            complement(2546..2893)
                     /locus_tag="ACL29Z_001730"
     CDS             complement(2546..2893)
                     /locus_tag="ACL29Z_001730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000434646.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin"
                     /protein_id="HGR0069999.1"
                     /translation="MEQFLDNIKDLEVTTVVRAQEALDKKETATFFIGRKTCPYCRKF
                     AGTLSGVVAETKAHIYFINSEEPSQLNDLQAFRSRYGIPTVPGFVHITDGQINVRCDS
                     SMSAQEIKDFAGL"
     gene            complement(3004..4722)
                     /locus_tag="ACL29Z_001731"
     CDS             complement(3004..4722)
                     /locus_tag="ACL29Z_001731"
                     /EC_number="5.4.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004252698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016868 - intramolecular
                     phosphotransferase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phospho-sugar mutase"
                     /protein_id="HGR0070000.1"
                     /translation="MSYQENYQKWVDFVELPDYLRQDLENMDEKTKEDAFYTNLEFGT
                     AGMRGLVGAGTNRINIYVVRQATEGLARLIESKGGNEKERGVAIAYDSRHFSPEFAFE
                     SAAVLAKHGIKSYVFESLRPTPELSFAVRHLNCFAGIMVTASHNPAPFNGYKVYGEDG
                     GQMPPHDADALTTYIRAIENPFAVEVADVETEKASGLIEVIGEAVDIEYLKEVKDINI
                     NPALIEEFGKDMKIVYTPLHGTGEMLARRALAQAGFDSVQVVEAQATADPDFSTVTSP
                     NPESQAAFALAEELGRQVGADVLVATDPDADRVGVEVLQKDGSYLNLSGNQIGAIMAK
                     YILEAHKNAGTLPENAALCKSIVSTDLVTKIAESYGATMFNVLTGFKFIAEKIQEFEE
                     KHNHTYMMGFEESFGYLIKPFVRDKDAIQAVLVVAELAAYYRSRGLTLADGIEEIYKE
                     YGYYAEKTISVTLSGVDGAEQIKAIMAKFRNNAPTEWNATAITVVEDFKAQTATVADG
                     TVTNLTTPPSDVLKYTLADGSWIAVRPSGTEPKIKFYIAVVGETNEESQAKIANIEAE
                     INAFVK"
     gene            4956..5800
                     /locus_tag="ACL29Z_001732"
                     /pseudo
     CDS             4956..5800
                     /locus_tag="ACL29Z_001732"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_078372828.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS630 family transposase"
     gene            5922..6164
                     /locus_tag="ACL29Z_001733"
     CDS             5922..6164
                     /locus_tag="ACL29Z_001733"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000284543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0070001.1"
                     /translation="MYQNEDLYKKGLNVELAHQQIKGFFEAEFKNRINGVLNTKIKNS
                     TLNRVNKKTIHQSNKNSMINLKQKQRKMLKNKAILC"
     gene            6158..6412
                     /locus_tag="ACL29Z_001734"
     CDS             6158..6412
                     /locus_tag="ACL29Z_001734"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001842111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0070002.1"
                     /translation="MLNVDQDFMSISKSNKSGSDWKKTFTVRITNRLANDLNNVLKQV
                     DKDTPNTPTWLNSAASKAKDDDRVYKLLKTLIPGENYLSC"
     gene            6523..7629
                     /locus_tag="ACL29Z_001735"
     CDS             6523..7629
                     /locus_tag="ACL29Z_001735"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001021424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MucBP domain-containing protein"
                     /protein_id="HGR0070003.1"
                     /translation="MNIILIAKLLRENTNTKANALNNGWARSGSEEFKKFSHFVGVDK
                     GIVRTNVLTGKKLSDKIRKEVGSGDSKLGKGGYFSTGDVLLGKDVVSYTVQVFSENNE
                     RVGVNTQSHRVQYNLPILADFSVIQDTVEPSRTVVEKIIPKLNIPEEEKGKITEEIKK
                     KKKTSELAELISENVKVRYVDEQGRLLSLKNDTGIGEKESDGTYITNKKQLIGTSYNV
                     TDKKLSSMTTTDGKYYTFKEADTNSASLTGNIVSEGRTVTLVYRESEAPTTATVTANY
                     YKEGRQEKLVESVIKADLAIGSEYTTESKTIEGKTTTEDKEDRVITRKTTYTLVATPA
                     NAYQKTVQQLTITTVRMLRKQWFPKQQPLLRRRL"
     gene            7587..8195
                     /locus_tag="ACL29Z_001736"
     CDS             7587..8195
                     /locus_tag="ACL29Z_001736"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000248972.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009986 - cell surface [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HGR0070004.1"
                     /translation="MVPKTATSTETKTITRIIHYVDKVTNQNVKEDVVQPVTLSRTKT
                     ENKVTGVVTYGEWTTGNWDEVVSGKIDKYKDPDIPTVESQEVTSDSSDKEITVRYDRL
                     STPEKPIPQPNPEHPSVPTPNPELPNQETPTPDKPTPEPGTPKTETPVNPDPEVPTYE
                     TGKREELPNTGTEANATLASAGIMTLLAGLGLGFFKKKEDEK"
     gene            8419..9288
                     /gene="gla"
                     /locus_tag="ACL29Z_001737"
     CDS             8419..9288
                     /gene="gla"
                     /locus_tag="ACL29Z_001737"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000348128.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015267 - channel activity [Evidence IEA];
                     GO_process: GO:0006071 - glycerol metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aquaglyceroporin Gla"
                     /protein_id="HGR0070005.1"
                     /translation="MDFTWALKYATEFLGTAILIILGNGAVANVELKGTKGHQSGWIV
                     IAVGYGMGVMIPALMFGNVSGNHINPAFTLGLAVSGLFPWAQVVPYIIAQVLGAIFGQ
                     ALVVATYRPFYLKTENPNNILGTFSTISSIDHGTKESRYAATVNGLINEFVGSFVLFF
                     AALGLTKNFFGAEVLQFMKQKAIEAGQTVDFSDLAIKAQVAPHTASGLSVAHLALGFL
                     VMALVTSLGGPTGPALNPARDLGPRLLHAFLPKSVLGEHKGDSKWWYSWVPVVAPIAA
                     AIAAVAVFKFLYL"
     gene            10326..11279
                     /locus_tag="ACL29Z_001738"
     CDS             10326..11279
                     /locus_tag="ACL29Z_001738"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001155321.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IS30-like element ISSpn8 family transposase"
                     /protein_id="HGR0070006.1"
                     /translation="MQEHYTPKGKHLTIDNRRLIERWKNENKSNREIAGLLGKAPQTI
                     HNEVKRGTTLQQVRKGLYKKVYSADYAQTVYQFNRKRSVKKLILTKEIREKILHYHKQ
                     KFSPEMMVNKKQVKVGISTIYYWFHNGHLGLTKADMLYPRKRKGVKKQASPNFKPAGK
                     SIEERPDVINLRLENGHYEIDTVLLTKIKNYCLLVLTDRRSRHQIIRLIPNKTAESVN
                     QALTLLLGEHRILSITADNGSEFKRLSEVFPEEHIYYAHAYSSWERGSNENYNRLIRR
                     WLPKGTKKTTPKEVAFIENWINNYPKKCLDYKSPSEFLLGG"
     gene            11443..12639
                     /gene="tuf"
                     /locus_tag="ACL29Z_001739"
     CDS             11443..12639
                     /gene="tuf"
                     /locus_tag="ACL29Z_001739"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014335040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003746 - translation elongation factor
                     activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_process: GO:0006414 - translational elongation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Tu"
                     /protein_id="HGR0070007.1"
                     /translation="MAKEKYDRSKPHVNIGTIGHVDHGKTTLTAAITTVLARRLPSSV
                     NQPKDYASIDAAPEERERGITINTAHVEYETEKRHYAHIDAPGHADYVKNMITGAAQM
                     DGAILVVASTDGPMPQTREHILLSRQVGVKHLIVFMNKVDLVDDEELLELVEMEIRDL
                     LSEYDFPGDDLPVIQGSALKALEGDSKYEDIVMELMNTVDEYIPEPERDTDKPLLLPV
                     EDVFSITGRGTVASGRIDRGIVKVNDEIEIVGIKEETQKAVVTGVEMFRKQLDEGLAG
                     DNVGVLLRGVQRDEIERGQVIAKPGSINPHTKFKGEVYILTKEEGGRHTPFFNNYRPQ
                     FYFRTTDVTGSIELPAGTEMVMPGDNVTIDVELIHPIAVEQGTTFSIREGGRTVGSGM
                     VTEIEA"
     gene            complement(12748..13331)
                     /locus_tag="ACL29Z_001740"
                     /pseudo
     CDS             complement(12748..13331)
                     /locus_tag="ACL29Z_001740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000436304.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
BASE COUNT         4233 a         2424 c         2823 g         3911 t
ORIGIN      
        1 aaacatatag aactgtagtt tatctctttt gatagctacg gtttttattt gtatatggta
       61 gaatcttttt acaaaaatac ttggtaatct tgtttattca tgctataata ggaacaatta
      121 cttttaggag gtgcagtatg tcttatttat ttgagatatt accgagttta ctgaatggtg
      181 cgagcacgac tgtacaggtc tttgcactgg tcttgctatt ttcgattccc ttgggcgttt
      241 tgattgcctt tgccttgcaa gtccattgga agcccctcca ttatctgatt aacatttaca
      301 tctgggttat gcgaggaacc cccttactct tgcaactgat ttttatctat tatgtgctcc
      361 caagtattgg gattcgttta gaccgccttc ctgcagctat tattgccttt gttctcaact
      421 atgcagctta ctttgcagaa attttccgtg ggggaattga cactattcca agaggacagt
      481 atgaggccgc caaggtcttg aagtttagcc cttttgacag agtgcgctat attatcttgc
      541 cccaagtgac caagatcgtt cttcctagtg tctttaatga agttatgagt ttggtcaagg
      601 atacttcttt ggtctatgct ctcggaattt cagaccttat cttggctagt cgaacagctg
      661 ctaaccgcga tgctagtcta gttcctatgt tcttggcagg agccatttat ttgattttga
      721 ttgggattgt gacaattatt tccaaaaaag ttgagaagaa gtatagttat tatagatagg
      781 aggctgccat gttagaatta cgaaatatca ataaagtctt tggagacaaa caaatcctgt
      841 ctaatttcag tctaagtatt cctgaaaagc aaatcctggc tatcgttgga ccttctggtg
      901 gaggtaagac aactctttta cgtatgcttg caggtcttga aaccattgat tcagggcaaa
      961 tcttttataa tggacaacct ttagagctgg atgaattgca gaagcgcaat ctactgggat
     1021 ttgtcttcca agattttcaa ctatttcctc atctatcagt tctggaaaat ttgactttat
     1081 cgcctgtgaa gaccatggga atgaagcagg aagaggctga gaagaaggcg agtggactct
     1141 tggaacagtt aggactagga ggacacgcag aggcctatcc tttctcacta tctggtgggc
     1201 aaaagcagcg ggtggctttg gcgcgtgcta tgatgattga cccagaaatc attggctacg
     1261 atgaaccaac ttctgccctg gatccagaat tacgtttgga agtggagaag ctaatcttgc
     1321 aaaataggga acttgggatg acccagattg tggttaccca tgatttgcag tttgctgaaa
     1381 atatcgcaga tgtattattg aaagtagaac ctaaatagga ggaaaaatgg atgaaaaaat
     1441 ggatgcttgt attagtcagt ctgatgactg ctttgttctt agtagcttgt gggaaaaatt
     1501 ctagcgaaac tagtggagat aattggtcaa agtaccagtc taacaagtct attactattg
     1561 gatttgatag tacttttgtt ccaatgggat ttgctcagaa agatggttct tatgcaggat
     1621 ttgatattga tttagctaca gctgtttttg aaaaatacgg aatcacggta aattggcaac
     1681 cgattgattg ggatttgaaa gaagctgaat tgacaaaagg aacgattgat ctgatttgga
     1741 atggctattc cgctacagac gaacgccgtg aaaaggtggc tttcagtaac tcatatatga
     1801 agaatgagca ggtattggtt acgaagaaat catctggtat cacgactgca aaggatatga
     1861 ctggaaagac attaggagct caagctggtt catctggtta tgcggacttt gaagcaaatc
     1921 cagaaatttt gaagaatatt gtcgctaata aggaagcgaa tcaataccaa acctttaatg
     1981 aagccttgat tgatttgaaa aacgatcgaa ttgatggtct attgattgac cgtgtctatg
     2041 caaactatta tttagaagca gaaggtgttt taaacgatta taatgtcttt acagttggac
     2101 tagaaacaga agcttttgcg gttggagccc gtaaggaaga tacaaacttg gttaagaaga
     2161 taaatgaagc tttttctagt ctttacaagg acggcaagtt ccaagaaatc agccaaaaat
     2221 ggtttggaga agatgtagca accaaagaag taaaagaagg acagtaagat aaaatagtgg
     2281 ctgaaactgc gttttgatta gcaaaacgta gttttttttg taatctagga aaacgataat
     2341 agcgattgaa tatggataat tgaatatgga atagcccact gtgatttcta aaacattgtt
     2401 aaaaattgat ttgacttcca aaattaaaat gttctgtaat gaaatactga tgtaactgtt
     2461 ttaggaacaa taaaacgcat aatatcaagg tttttgcacc ttacattatg cgtttttgtg
     2521 attttaagac ttgttagctg attttttaca atcctgcgaa atctttgatt tcttgtgctg
     2581 acattgaaga gtcgcaacgg acgttgattt gtccatctgt aatatgaaca aaacctggta
     2641 cagttgggat tccatagcgt gagcggaatg cttgcaaatc attgagttgg cttggttctt
     2701 cactattgat gaagtaaatg tgagctttgg tttcagctac gacacctgac aatgtacctg
     2761 caaatttacg gcagtaaggg caagttttgc gaccgataaa gaaggttgca gtttcttttt
     2821 tatcaagagc ttcttgcgca cgcacaactg tagtgacttc aaggtctttg atgttatcta
     2881 aaaattgttc catgagatta cctcgctttc attgataagt ctagtatgcc ataaagtttc
     2941 taaaattgct tagatttgat acgaaaaaag atgaggttgg ttggtctcat cttttatagg
     3001 tctttatttt acaaatgcat tgatttctgc ttcgatgtta gcaatcttag cttgtgattc
     3061 ttcgttggtt tcccctacaa ctgcaatgta gaacttgatt tttggttctg tacctgaagg
     3121 gcgaacggca atccatgaac cgtcagcaag tgtgtatttc aacacatcac ttggaggagt
     3181 tgtcaagttt gtaacagtac cgtcagcaac agtagcagtt tgtgccttga agtcttctac
     3241 gacagtgata gctgttgcgt tccattctgt tggagcattg ttgcggaatt tagccataat
     3301 cgctttgatt tgttcagcac catcgacacc tgaaagagta acagagattg ttttttctgc
     3361 gtagtagcca tattctttat agatttcttc gataccgtca gcaagtgtca aaccacgaga
     3421 acggtagtag gcagcaagtt cagcaactac aagaacggct tggatggcat ctttatcacg
     3481 tacaaatggt ttaatcaagt aaccgaagct ttcttcaaat cccatcatgt aagtgtggtt
     3541 gtgtttttct tcgaattctt ggattttttc agcgataaat ttgaaacctg tcaagacgtt
     3601 gaacatagtt gcgccgtagc tttcagcaat cttcgttacc aagtcagttg aaacgataga
     3661 tttgcagaga gcggcatttt caggaagagt tccagcgttt ttgtgagctt ccaagatgta
     3721 tttagccatg atagcaccga tttggttacc tgaaaggttg aggtagctac catctttttg
     3781 aagaacttca acaccaacac ggtcagcgtc tgggtcagtt gcgacaagaa catctgcacc
     3841 aacttgacga ccaagttctt cagcaagggc aaaggctgct tggctttctg ggtttggaga
     3901 tgttacagtt gaaaagtctg ggtcagcagt tgcttgcgct tcaacaactt gaacagagtc
     3961 aaatcctgct tgggcaagag cacgacgagc caacatttca ccagtaccat gaagtggtgt
     4021 gtagacaatc ttcatgtctt taccaaattc ttcaatcaag gctgggttga tgtttatgtc
     4081 cttaacctct ttaaggtatt ctatgtcaac agcttcgccg ataacttcaa tcaagccaga
     4141 agctttttca gtttccacat cagcaacttc aactgcaaat gggttttcga ttgcacggat
     4201 ataagtagtc aaagcgtccg catcgtgtgg aggcatttgt ccaccgtctt caccgtaaac
     4261 cttgtaaccg ttaaatggag cagggttgtg gctggctgtg accatgatac ctgcgaaaca
     4321 gttgagatga cgaactgcaa atgatagttc tggagtcgga cgaaggcttt caaatacgta
     4381 agatttgatg ccgtgtttag caagaactgc cgcagattca aaggcaaact caggtgagaa
     4441 gtgacggcta tcgtaggcaa ttgctacacc gcgttctttc tcgtttccac cttttgactc
     4501 aatcaaacga gccaatcctt cagtagcttg gcgaacaacg tagatgttga tacggtttgt
     4561 accagcacca accaagccac gcatacctgc agtaccaaat tcaagatttg tatagaaggc
     4621 atcttcctta gttttttcgt ccatattttc caaatcttga cgaaggtagt caggaagctc
     4681 cacaaaatca acccatttct ggtaattttc ttggtaagac attcaaattc tcctttattt
     4741 ttaaaacatt taatcagttt aattatatca ttttttttag ttttagtaaa accttatctg
     4801 cttcgaacat ctcttcaaac caggtcagat tgaattttgg ggttatatga tgttgaggct
     4861 aggaaaaatt caatttcagt aaaaaaagta agtcttctca taacaaaaca ttgatatagt
     4921 tacttagttt taaacaagca tattataata aagctatggc atatagtact gattttaaac
     4981 agcgagcatt agattacatc aaagaggggc acagccatgt cgaggcagcc aagttttttg
     5041 gtgttggcgt cagaactctc ttcacgtggg aaaagaaaga cgtgaacaag aacacataga
     5101 gaggaaaaag cgagtcgtca aaaaccgaaa gattccttta gaggaattga aagcctttgt
     5161 agaggctcat ccagatgctt ttttacggga aattgcggca cattttgatt gtgctgttcc
     5221 ttcagtatgg gcagctttaa agcagattaa ggtcacttta aaaaaagatg acgagcttta
     5281 aggaacaaga cccagaaaag tagccttatt tcttaagaat tttaatagtt taaagcacct
     5341 agcacctgtt tatattgatg aaacaggaat cgaccgctat ctctatcgtc cttatgcagg
     5401 ggctcctaga ggggagaaag tctatgaaaa gattagcgga cgtcgttttg agcgaacttc
     5461 aattgttgca ggacaagtag acggagagtt tatagctccc atgatttaca agaaaagcat
     5521 gacaagcgat ttctttgtgg agtggttcaa aacgcaactc ctacctgctt tgaagacacc
     5581 tcatgttatt gtcatgggca atgctggttt tcatcccaag aacattttgg atgaactctg
     5641 catccaagat aaacactttt tcttacctct accaccttat tcaccggatt tgaatcctat
     5701 tgagcaagct tgggctatct tgaaaaagaa agtgacggat gtattaaggg aagttccaac
     5761 tatttttgaa tgtttggaat gcttttttaa aactagatga ctataacggt tctaaaggaa
     5821 cctatcgagt agtcattaaa actaaggata ctgctggtta agagaagacg gtatacaatc
     5881 aaaccattca ccgtgtagcc gaaatcgttc agaatgaaga cttgtatcag aatgaagact
     5941 tgtataagaa aggtttgaat gttgaacttg cgcaccaaca aattaaggga ttttttgaag
     6001 cagagtttaa aaatcgtatt aatggagttc ttaatactaa aataaaaaat agtacattaa
     6061 atcgtgtaaa taaaaaaact atacaccaga gcaacaaaaa ctccatgatc aatttgaagc
     6121 agaagcaacg gaagatgcta aaaaacaagg cgatattgtg ttgaatgttg accaggattt
     6181 catgagcata tctaagtcta ataaaagtgg ttcagactgg aagaaaactt tcacagtgag
     6241 gataaccaat aggctagcaa atgacttgaa taatgtcttg aaacaggttg ataaagatac
     6301 tcctaatacc ccaacttggc taaactcagc tgcttctaaa gctaaagatg atgacagagt
     6361 atataaacta ctgaagactc ttataccagg agaaaattac ctatcatgtt aaggataatc
     6421 agctagaagt agaaacagat aaatacacat atactgccgc tagaaatggt agtaaggaag
     6481 ttggtattca agagtcagat atagcagcaa ctctaagtgc cgatgaatat aattctaatc
     6541 gccaaacttt tgagagagaa tacaaataca aaagcaaatg cccttaataa tggttgggct
     6601 agatctggtt ctgaagagtt caaaaagttc tcccactttg taggggtaga caaagggatt
     6661 gtgcgaacga atgtactgac tggtaaaaaa ctatctgata agattaggaa agaagtgggc
     6721 tctggagata gcaaactagg aaaaggcggc tatttctcta ctggggatgt tctattagga
     6781 aaagatgttg tttcttatac cgtacaagta ttttcagaga ataatgaaag agtaggagta
     6841 aacactcaaa gtcaccgtgt tcagtataat ctcccaattc tagctgactt ttcagtcatc
     6901 caagatactg tggaaccatc acgaaccgtt gttgaaaaaa tcattccaaa actaaatatt
     6961 cccgaagaag agaaagggaa aataaccgaa gaaatcaaga aaaagaaaaa aacctcagaa
     7021 ttggcagaac taatctcaga aaatgtgaaa gttcgctatg ttgatgaaca agggcgtttg
     7081 ctatcattga aaaatgatac tggaattgga gaaaaagaaa gtgacggaac ctacattacc
     7141 aataaaaaac aactgattgg taccagctat aatgtcacag ataaaaaact cagtagcatg
     7201 actactactg acggaaaata ttatactttt aaagaagcag atacaaattc tgcaagttta
     7261 actgggaata ttgtaagcga aggtagaaca gtgaccttag tttatagaga aagcgaagcg
     7321 ccaaccactg ctacagtaac agccaattac tataaagaag gtaggcaaga gaagttggta
     7381 gagtctgtta taaaagctga tttagcgata ggttctgagt ataccacaga atcaaaaact
     7441 attgaaggga aaacaacaac tgaggacaaa gaagaccgag ttatcacaag gaaaacaaca
     7501 tacaccttgg tagcaactcc tgcaaatgcg taccagaaga cggtgcaaca gttgactatt
     7561 actaccgtga gaatgttgag gaaacagtgg ttcccaaaac agcaacctct actgagacga
     7621 agactataac gcgtatcatt cattacgttg ataaagttac gaaccaaaat gtaaaagaag
     7681 atgttgttca acctgtaacc ttaagccgta caaaaactga gaacaaggtc acgggagttg
     7741 taacctacgg tgaatggaca acaggaaact gggacgaggt tgtatctggt aagattgaca
     7801 agtacaaaga tccagatatt ccaacagttg aatcacaaga agttacgtca gactctagtg
     7861 ataaagaaat aacggtaagg tatgaccgtt tatcaacacc agaaaaacca atcccacaac
     7921 caaatccaga gcatccaagt gttccgacac caaacccaga actaccaaat caagagactc
     7981 caacaccaga taaaccaact ccagaaccag gtactccaaa aactgaaact ccagtgaatc
     8041 cagacccaga agttccgact tatgagacag gtaagagaga ggaattgcca aacacaggta
     8101 cagaagctaa tgctaccttg gctagtgctg gtatcatgac cttgttagct ggtctaggat
     8161 taggattttt caagaaaaaa gaagatgaaa aataatagat tttagaatct aggaaccagg
     8221 aaaagctcac agatgtgggc ttttttcctg gttttgagaa cgaggtcttt cgtaaagaat
     8281 aaaaacgctt acaagtctgt tgaactggga aactatgaat cctatttttt taaaaatatt
     8341 tccagaaatc agttgctaaa tagggtaaaa attgataaaa taaggaatat ctaaaaaatt
     8401 ttaaggagaa tctagcaaat ggatttcaca tgggcactga agtatgccac tgaatttttg
     8461 ggaactgcca ttttgatcat tcttgggaat ggtgcagttg ccaacgttga acttaaaggt
     8521 acgaaaggtc accaaagtgg ctggatcgtc atcgctgttg gttatggtat gggggttatg
     8581 atcccagcct tgatgtttgg taacgtatct gggaatcaca tcaaccctgc tttcactcta
     8641 gggcttgcag ttagcggtct tttcccttgg gcacaagtgg taccttacat tatcgcgcaa
     8701 gtcttggggg ctatctttgg ccaagcctta gttgtggcaa cataccgtcc attctacttg
     8761 aaaactgaaa acccaaataa catcttggga actttctcaa ctatttcaag tattgaccat
     8821 ggtacaaaag aaagtcgcta tgcagcaact gtcaatggtt tgattaatga gtttgttggt
     8881 tcatttgttt tgttctttgc agctcttggt ttgactaaaa acttctttgg tgctgaagtg
     8941 cttcaattca tgaaacaaaa ggcaatagaa gcaggacaaa cagttgattt ttctgacttg
     9001 gctattaaag cacaggtggc tccacacact gcttcaggac tttctgtggc tcacttggca
     9061 cttggattcc tcgttatggc tttggtaaca tcacttggag gacctacagg acctgccttg
     9121 aacccagccc gtgacttggg accacgtctc cttcatgctt tccttccaaa atcagttctt
     9181 ggtgagcata aaggcgattc aaaatggtgg tattcttggg taccagtagt agcacctatc
     9241 gcagcagcaa ttgcggcagt agctgtattc aaattccttt atctctaaga aatagctcct
     9301 ttaacatttg agtgagcacc atctataagt aagagaggat cagactggtt ctctcttttt
     9361 gattttttag ggaaatgaaa gaaactctaa acaaactcct ctccagcagt ggtttagaag
     9421 tctcagtggg ctattccagc ttcaatgggc tatagtaggt tgcagttgaa ataatagacc
     9481 cttgtttcta aaacattgtt agaaattggt ttgaattctc caatcaaatt gtgcagtttt
     9541 cattctacta tatattatcg gagatgggtt ccctatcttg taagtctgct ttatagtggg
     9601 ttgaagttgg aatagtcctc ccttctttct caaacattgt gaggaattga tttaccttcc
     9661 tcaacaaaat gttcagtttc tatttcattt tgctataaaa taagcgatta ggggggtatt
     9721 cttcgaccta cattgactct gctgagtcct atgattgtta tcgttttatc tgcaatttta
     9781 tactcaatga aaatcaaagg gcaaactaag aagctagccg caggttgttc aaaacacagt
     9841 tttgaggttg tatagtagat tgaaactaga atagtacaca tctacttcta aaacattgtt
     9901 agaaatcgat ttgactgtcc tgatcgattt gctctattct tgtttcattt tactatataa
     9961 accagagact gtttacattt tcagcaagtg agtggatgga taatgctgaa aactccttga
    10021 aggataagtc tatttagtac tttctattaa ttagttaaat ttttactgaa agttctataa
    10081 tgaagttagc caccttacct tagtcaagaa ttagatgttt cactatgttt gagtaagttg
    10141 atgatttcat ttgataacag gtttgaaact gttaggctag gtggccaagg ctaatcatag
    10201 ccttggttta gctgaaaaaa caggttcaag ggttcctgtt gtcaaatgaa atgtgattta
    10261 aggtataaga aaacacctct gtgctatact tgttgttcac cacaaacaca aggaaaggca
    10321 cagagatgca agaacattat accccaaaag ggaaacattt gacaatagat aaccgtcgct
    10381 tgattgagcg gtggaagaat gaaaataagt ccaatcgtga aattgcaggc ttgttaggaa
    10441 aggcgcctca aacgattcat aatgaagtca aaagaggtac aactttacaa caagtgagaa
    10501 aagggctata caaaaaggtc tattctgccg attacgcaca aactgtttac caattcaatc
    10561 gaaaacggtc ggtgaaaaag ttaattttaa caaaggaaat cagagagaag atcttacact
    10621 atcataagca aaaattttcg cctgaaatga tggttaacaa gaagcaagtg aaagttggta
    10681 tttcaaccat ctactactgg tttcataatg gtcatttagg attgacgaag gccgacatgc
    10741 tttatcccag aaaaaggaaa ggtgtcaaga agcaagctag tccgaacttt aagccggcag
    10801 gtaaatctat cgaagaacgt cctgacgtta ttaatcttcg cttggaaaat ggtcattatg
    10861 aaattgatac cgtcctactg actaagataa aaaattattg cctgttagtc ttaaccgacc
    10921 ggcggagcag acaccaaatt ataaggttaa ttccaaataa aactgctgaa tctgtcaatc
    10981 aggcgcttac gttactatta ggggagcatc gtattctgtc cattactgca gataatggtt
    11041 cggagttcaa acgattgtct gaggtatttc ctgaggaaca tatctactac gcacatgctt
    11101 actcttcatg ggagagaggt tcaaatgaaa attataatcg attaattcgg agatggttac
    11161 ctaaaggaac caagaaaacg actccgaaag aagtagcttt tatcgaaaat tggattaaca
    11221 actaccctaa aaaatgcttg gactacaagt cgccaagtga atttcttttg ggtggctaac
    11281 ttcaacttga aatttggggt taaattttta ccaagaataa ttcacaaaaa cgttgtaaaa
    11341 cacttgcaat ttagctgaaa tttgataaaa tagtaaggaa agttagactg tattgcctac
    11401 tgtctatcta taaaatatat tttattggag gcttttactc aaatggcaaa agaaaaatac
    11461 gatcgtagta aaccacacgt taacattggt actatcggac acgttgacca cggtaaaact
    11521 accctaactg cagctatcac aactgttttg gcacgtcgct tgccttcatc agttaaccaa
    11581 cctaaagact atgcgtctat cgatgctgct ccagaagaac gcgaacgcgg tatcactatc
    11641 aacactgcgc acgttgagta cgaaactgaa aaacgtcact acgctcacat cgacgctcca
    11701 ggacacgcgg actacgttaa aaacatgatc actggtgctg ctcaaatgga cggagctatc
    11761 cttgtagtag cttcaactga cggaccaatg ccacaaactc gtgagcacat ccttctttca
    11821 cgtcaggttg gtgttaaaca ccttatcgtc ttcatgaaca aagttgactt ggttgacgac
    11881 gaagaattgc ttgaattggt tgaaatggaa atccgtgacc tattgtcaga atacgacttc
    11941 ccaggtgacg atcttccagt tatccaaggt tcagcactta aagctcttga aggtgactct
    12001 aaatacgaag acatcgttat ggaattgatg aacacagttg atgagtatat cccagaacca
    12061 gaacgtgaca ctgacaaacc attgcttctt ccagtcgagg acgtattctc aatcactgga
    12121 cgtggtacag ttgcttcagg acgtatcgac cgtggtatcg ttaaagtcaa cgacgaaatc
    12181 gaaatcgttg gtatcaaaga agaaactcaa aaagcagttg ttactggtgt tgaaatgttc
    12241 cgtaaacaac ttgacgaagg tcttgctgga gataacgtag gtgtccttct tcgtggtgtt
    12301 caacgtgatg aaatcgaacg tggacaagtt atcgctaaac caggttcaat caacccacac
    12361 actaaattca aaggtgaagt ctacatcctt actaaagaag aaggtggacg tcacactcca
    12421 ttcttcaaca actaccgtcc acaattctac ttccgtacta ctgacgttac aggttcaatc
    12481 gaacttccag caggtactga aatggtaatg cctggtgata acgtgacaat cgacgttgag
    12541 ttgattcatc caatcgccgt agaacaaggt actacattct ctatccgtga gggtggacgt
    12601 actgttggtt caggtatggt tacagaaatc gaagcttaat tcgatttagt tcccagaaga
    12661 acaattattt aagtcagaca ctaaaagaat cttgcttggc aaggttcttt tttggttctt
    12721 tgtcaactgt agtgggttga aaaaaaacta agctcgagaa aggacaaatt tcgtcctttc
    12781 tttttgatgt tcagggcgat gaaaatccgt tttttgaagt tttcaaagtt ccgaaaacca
    12841 aaggcattgc gcttgataag tttgatgaga ttattggtcg cttccaattt ggcgtttgaa
    12901 tagggtagtt gaagggcgtt gacgattttc tttttgtcct ttagaaaggt tttaaagaca
    12961 gtctgaaaaa gaggatgaac ctgcttaaga ttgtcctcaa tgagtccgaa aaatttctcc
    13021 ggttccttat tctgaaagtg aaacagcaag agttgataga gctgatagtg gtgtttcaag
    13081 tcttccgaat aactcaaaag cttgtttaaa atctctttat tggttaagtg catacgaaaa
    13141 gtaggacgat aaaatcgctt atcactcagt ttacgactat cctgttgtat gagcttccag
    13201 tagcgcttga tagccttgta ttcatgagac tttcgatgaa actgattcat gatttggaca
    13261 cgcacacgac tcatagtacg gctaagatgt tgtacaatgt gaaagcgatc caacacgatt
    13321 ttagcattcg ggagtgaaac agtctgggag actgtttcag cctgagccta gaaatttgaa
    13381 agcgaagctg t
//
LOCUS       DBEJAU010000052        12934 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC323 isolate 683620
            SAMN38261939-rid24807223.denovo.052, whole genome shotgun sequence.
ACCESSION   DBEJAU010000052 DBEJAU010000000
VERSION     DBEJAU010000052.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261939
            Sequence Read Archive: SRR26833919
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 12934)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12934)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576303.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576303.1
            Genome Coverage       :: 154x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/19/2025 01:05:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,121
            CDSs (total)                      :: 2,078
            Genes (coding)                    :: 1,943
            CDSs (with protein)               :: 1,943
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 36
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 72 of 135
            Pseudo Genes (incomplete)         :: 63 of 135
            Pseudo Genes (internal stop)      :: 51 of 135
            Pseudo Genes (multiple problems)  :: 46 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12934
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261939-rid24807223.denovo.052"
                     /strain="GPSC323"
                     /isolate="683620"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            103..272
                     /locus_tag="ACL29Z_001741"
                     /pseudo
     CDS             103..272
                     /locus_tag="ACL29Z_001741"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000710121.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase family lipid kinase"
     gene            472..3747
                     /gene="rexB"
                     /locus_tag="ACL29Z_001742"
     CDS             472..3747
                     /gene="rexB"
                     /locus_tag="ACL29Z_001742"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002206154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004518 - nuclease activity [Evidence
                     IEA];
                     GO_process: GO:0000724 - double-strand break repair via
                     homologous recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent nuclease subunit B"
                     /protein_id="HGR0070008.1"
                     /translation="MKLLYTDIRTSLTEILTREAEELVAAGKRVFYIAPNSLSFEKER
                     AVLECLSQQASFSITVTRFAQMARYLVLNDLPVKTTLDDIGLGLAFYKCLAELDPKDL
                     RVYGAIKQDPQLIQQLIELYHEMTKSQMSFLDLENLTDEDKRTDLLLIFEKVTAYLNQ
                     GQLAQGSQLSHLIEAIENDKVSSDFNQITLVIDGFTRFSAEEERVVDLLHGKGVEIVI
                     GAYASKKAYTSPFSEGNLYQASVKFLHHLASKYQTPAQDCSQTHEKMDSFDKASRLLE
                     SSYDFSELALDVDEKDRENLQIWSCLTQKEELELVARSIRQKLHENSDLSYKHFRILL
                     GDVASYQLSLKTIFDQYQIPFYLGRSEAMAHHPLTQFVESILALKRYRFRQEDLINLL
                     RTDLYTDLSQSDIDAFEQYIRYLGINGLPAFQQIFTKSHHGKFNLERLNVLRLRILAP
                     LETLFASRKQKAENLLQKWSVFLKEGAVTKQLQDLTTTLEAVEQERQAEVWKAFCHVL
                     EQFATVFAGSQVSLEDFLALLHSGMSLSQYRTIPATVDTVLVQSYDLIAPLTADFVYA
                     IGLTQDNLPKISQNTSLLTDEERQNLNQATEEGVQLLIASSENLKKNRYTMLSLVNSA
                     RKQLFLSAPSLFNESESKESAYLQELIHFGFRRREKRMNHKGLSKEDMGSYHSLLSSL
                     VAYHQQGEMSDTEQDLTFVKVLSRVIGKKLDLQGLENPAIPTSPSSKTLAKDTLQALY
                     PAKQEFYLSTSGLTEFYRNEYSYFLRYVLGLQEELRLRPDARSHGNFLHRIFERALQL
                     PNEDSFDQRLEQAIQETSQEREFEAIYQESLEAQFTKEVLLDVARTTGHILRHNPAIE
                     TIKEEANFGGKDQAFIQLDNGRSVFVRGKVDRIDRLKANGAIGVVDYKSSLTQFQFPH
                     FFNGLNSQLPTYLAALKREGKQNFFGAMYLEMAEPVQSLMAVKSLAGAVVEASKSMKY
                     QGLFLEKESSYLGEFYNKNKANQLTDEEFQLLLDYNAYLYKKAAEKILAGRFAINPYT
                     ENGRSIAPYVQQHQAITGFEANYHLGQARFLEKLDLADGKRLVGEKLKQAWFEKIREE
                     LNR"
     gene            3744..7394
                     /gene="addA"
                     /locus_tag="ACL29Z_001743"
     CDS             3744..7394
                     /gene="addA"
                     /locus_tag="ACL29Z_001743"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000767270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003678 - DNA helicase activity [Evidence
                     IEA];
                     GO_function: GO:0016818 - hydrolase activity, acting on
                     acid anhydrides, in phosphorus-containing anhydrides
                     [Evidence IEA];
                     GO_process: GO:0000724 - double-strand break repair via
                     homologous recombination [Evidence IEA];
                     GO_process: GO:0006302 - double-strand break repair
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helicase-exonuclease AddAB subunit AddA"
                     /protein_id="HGR0070009.1"
                     /translation="MKLIPFLSEEEIQKLQEAEANSSKEQKKTAEQIEAIYTSGQNIL
                     VSASAGSGKTFVMAERILDQLARGVEISQLFISTFTVKAATELKERLEKKISKKIQET
                     DDVDLKQHLGRQLADLPNAAIGTMDSFTQKFLGKHGYLLDIAPNFRILQNQSEQLLLE
                     NEVFHEVFEAHYQGKQKESFSHLLKNFAGRGKDERGLRQQVYKIYDFLQSTSNPQKWL
                     SESFLKGFEKADFTSEKEKLTEQIKQALWDLESFFRYHLDNDAKEFAKAAYLENVQLI
                     LDEIGSLNQEFDSQAYQAVLARVVAISKEKNGRALTNASRKADLKPLADAYNEERKTQ
                     FTKLGQLSDQIAILDYQERYHGDTWKLAKTFQSFMSDFVEAYRQRKRQENAFEFADIS
                     HYTIEILENFPQVRESYQERFHEVMVDEYQDTNHIQERMLELLSNGHNRFMVGDIKQS
                     IYRFRQADPQIFNEKFQRYAQNPQEGKLILLKENFRSSSEVLSATNDVFERLMDQEVG
                     EINYDNKHQLVFANTKLTPNPDNKAEFLLYDKDDTGEEEESQTETKLTGEMRLVIKEI
                     LKLHQEKGVAFKEIALLTSSRSRNDQILLALSEYGIPVKTDGEQNNYLQSLEVQVMLD
                     TLRVIHNPLQDYALVALMKSPMFGFDEDELARLSLQKAEDKVHENLYEKLVNAQKMAS
                     SQKGLIHTALAEKLKQFMDILASWRLYAKTHSLYDLIWKIYNDRFYYDYVGALPNGPA
                     RQANLYALALRADQFEKSNFKGLSRFIRMIDQVLEAQHDLASVAVAPPKDAVELMTIH
                     KSKGLEFPYVFILNMDQDFNKQDSMSEVILSRQNGLGVKYIAKMETGAVEDHYPKTIK
                     LSIPSLTYRQNEEELQLASYSEQMRLLYVAMTRAEKKLYLVGKGSREKLEVKQYPAAK
                     NGKLNSNTRLQARNFQDWLWAISKVFTKDKLNFSYRFIGEDQLTREAIGELETKSPLQ
                     DSSQADNRQSDTIKEALEMLKEVEVYNTLHRAAIELPSVQTPSQIKKFYEPVMDMEGV
                     EIAGQGQSVGKKISFDLPDFSTKEKVTGAEIGSATHELMQRIDLSQQLTLASLTETLK
                     QVQTSQAVRDKINLDKILAFFDTVLGQEILANTDHLYREQPFSMLKRDQKSQEDFVVR
                     GILDGYLLYENKIVLFDYKTDRYDEPSQLVDRYRGQLALYEEALSRAYSIENIEKYLI
                     LLGKDEVQVVKV"
     gene            7609..8787
                     /locus_tag="ACL29Z_001744"
     CDS             7609..8787
                     /locus_tag="ACL29Z_001744"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0070010.1"
                     /translation="MTLPVRKSLHDAVLQASKADTWEQATKEWNEVSLIFNGIGRSNC
                     VCGNAIKYAYELFNGVTGQRLFPIGSYCVRHFHRLSLDQQLEEEEKLLRKVENLTRKA
                     QKKEKIKVNKSDFDERLLKWLWEKGVFKPNRGNQFAPERDYQLFLEVFQGGSWTKAEP
                     KKKARMEEVLEKCIKPFLLGKSDDQLYLVKLGKEKIDYEQELRIQAEKERKKRDKIAK
                     QYADNLVLAMGPAERAYQDYFGFTETLTQEERKWEKILFGKNRAERAIKAKQYQKELE
                     KDQRIASQDPIERKQKQTWLLNSYFRELPEEKARFSRLLLEYRKSGEVPFSTEYLSDH
                     LIDFFYKMKAFEFEIAPEQVRDFLKKSLQEDHRSSAQGSWIEGILLNCLKPFLERLVI
                     "
     gene            8996..>12934
                     /locus_tag="ACL29Z_001745"
     CDS             8996..>12934
                     /locus_tag="ACL29Z_001745"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001845810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0004222 - metalloendopeptidase activity
                     [Evidence IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ZmpA/ZmpB/ZmpC family
                     metallo-endopeptidase-related protein"
                     /protein_id="HGR0070011.1"
                     /translation="MEKYFGEKQERFSFRKLSVGLVSATISSLFFMSVLASSSVDAQE
                     TAGVHYKYVADSELSSEEKKQLVYDIPTYVENDDETYYLVYKLNSQNQLAELPNTGSK
                     NERQALVAGASLAALGILIFAVSKKKVKNKTVLHLVLVAGMGNGVLVSVHALENHLLL
                     NYNTDYELTSGEKLPLPKEISGYTYIGYIKEGKTTSDFEVSNQEKSAATPTKQQKVDY
                     NVTPNFVDHPSTVQAIQEQTPVSSTKPTEVQVVEKPFSTELINPRKEEKQSSDSQEQL
                     AEHKNLETKKEEKISPKEKTGVNTLNPQDEVLSGQLNKPELLYREETIETKIDFQEEI
                     QENPDLAEGTVRVKQEGKLGKKVEIVRIFSVNKEEVSREIVSTSTTAPSPRIVEKGTK
                     KTQVIKEQPETGVEHKDVQSGAIVEPAIQPELPEAVVSDKGVPEVQPALSEAVVTDKG
                     EPAVQPELPEAVVSDKGEPAVQPELPEAVVTDKGDPEQVEPLPEYTGVQAGAIVEPEK
                     VEPEYAGVQAGAIVEPEQVAPLPEYTGVQAGAIVEPEKVEAPKEYTGVQAGAIVEPEK
                     VEAPKEYTGVQAGAIVEPEKVEPSKEYTGVQAGAIVEPEQIAPLPEYTGVQAGAIVEP
                     EKVEALKEYTGKIEQPSAEDTKPNNENTNTPEEMSIQKKSSALINMNFITDSSKVTGV
                     GSATFIAPNVLLTVAHNFINNSTDNTTGEFRGDKSKNVYEWVTPDGQKGTFTANNIHF
                     YNKKDYPKGFIYDLAVIKLPETTGREHVELVKNYSKVNLNDKLNVHGYPAGKYTHLKD
                     ATVEMEQEYANNTYGVQYQGGNPGMSGGGIFNANGEVIGVHQNGAQNRSGGLILSPTQ
                     LAWIKSIIAGNEIPPVYDELYRHKDEKKDDAKDEKEVIKKLELRNISSVELYSKDGNK
                     YRHVTSLASLPSNAENYFMKVKSENFKDVMLPVTSITNDTKDNRDVYKIVASANSLIQ
                     HENNNVLENYTYYLPKTQQSETGVYTSFKNLVDAMNSNPNGTFRLGATMDAREVELPD
                     GQESYVNNVFHGILVGTNNEKYYAIYNLKKPLFGELNGATVEKLSLKDVNISAKDDTA
                     TLAKEANNNTHIDNVHADGAIAGERSIGGLVSQVNNSTISNSSYTGRITNTYKTVASY
                     QIGGLVGKLSGPRGLIDKSFASIDLSSNATQGDQSIGGIVGAVENSALISNSYAEGNL
                     NNVQRFANVGGVVGNLWDPVGGLEKSGRLSNVLSDVNVTNGNAIAGYNFNGIKANGTY
                     SNKNNKVVNVVQEDDEILTKDSTVQRGEVLEDAQIKEKKATFVSKNTIKTE"
BASE COUNT         4290 a         2471 c         2717 g         3456 t
ORIGIN      
        1 gctcacaata agagagaact tttttacgaa aatctattga atatgccata aaaagattat
       61 accacattgt gtactatttt tggttcattt tactatagtt caatcattct atcaagaata
      121 ttgaatatat aaaggcacgt aatattaaaa cttcttctga tatcgaatta gagtccgatg
      181 ttgatggcga taaatcagac aatctacccg tcgacattaa gatactggga caacacattg
      241 aagtgtattc cgtacctaag aaacaatcat aaaactcaaa gccttgttac tgaggctttt
      301 ttattatgtg attttcagta gccagactta ttctatctaa tacaagtaaa gctaagtatt
      361 taagatttag cagataatga agaaaagaaa ggatggccta aatattttaa cagatttacg
      421 aggctaatca tggtataata tagggtgatg aaaaattcca acgaggctga gatgaaatta
      481 ctttatactg atattcgaac ttctttgaca gaaattctaa caagagaggc agaagagcta
      541 gttgcagctg gcaagcgggt cttctacatt gcccccaact ctctttcttt tgaaaaggaa
      601 cgcgccgtgc tggaatgctt gtcccagcag gcttcttttt cgattaccgt cacgcgcttt
      661 gctcaaatgg ctcgttatct ggtcctgaat gatttaccag ttaaaactac tcttgatgat
      721 atcggtcttg ggttggcctt ttacaaatgc cttgccgaac tcgatcccaa ggacttgcgt
      781 gtttatggcg ctattaagca ggatcctcaa ttgatccagc agttaattga gctttaccat
      841 gagatgacca aatctcagat gagttttttg gacttggaga atttaacaga tgaggataag
      901 aggacggatt tactcttgat ttttgagaaa gtaacagcct atcttaatca aggtcagtta
      961 gcccagggaa gtcagttgtc ccatttgatt gaggctattg agaatgacaa ggtaagtagt
     1021 gattttaatc aaatcacctt ggtcattgac ggctttactc gtttttctgc tgaggaagag
     1081 cgggttgtgg acttacttca cggcaaaggt gttgaaattg ttatcggggc ttatgctagt
     1141 aagaaagcct ataccagtcc ttttagcgag ggcaatctct accaagccag cgtaaaattt
     1201 ctccatcatc tggcttctaa ataccaaacg cctgctcagg actgttctca aactcatgag
     1261 aagatggata gttttgacaa ggcctctcgt ttgttggagt cttcttatga cttttcagaa
     1321 ctcgctttgg atgtcgatga gaaagaccgt gaaaatttac aaatctggtc ttgtttgacg
     1381 caaaaggagg agttggagct agtagcccgt agtattcgtc agaaattaca tgagaactca
     1441 gacctgagct acaagcattt tcgtattctc ttgggggatg tagcttctta ccagttatct
     1501 ctcaaaacca tttttgacca gtatcagatt cctttttatc ttggtagaag cgaagccatg
     1561 gctcatcatc ccttgactca gtttgtcgag tctattttag ctttaaaacg ttaccgtttt
     1621 cgtcaggagg atttgattaa tcttcttaga actgatttgt atactgacct cagtcagtct
     1681 gatattgatg cttttgagca atatatccgc tatcttggta tcaatggctt gccagccttt
     1741 cagcaaatct tcaccaaatc ccaccatgga aaatttaatc ttgagcgttt gaatgtcctc
     1801 cgcctgagaa ttttagcacc tcttgaaacc ctctttgcca gccgaaaaca aaaggctgaa
     1861 aacctcctac aaaaatggag tgtctttcta aaagaaggag ctgtgaccaa gcagttacaa
     1921 gatttgacaa ccactttgga agctgtagaa caggaaagac aagccgaagt ttggaaggct
     1981 ttctgccatg ttttagaaca atttgcgact gtttttgctg gttcacaggt tagtctggaa
     2041 gacttcctag ccttgctcca ttctggaatg agtttgtccc aataccgtac cattccagca
     2101 acagtggaca ctgttctggt gcagagttac gatttgattg caccattgac tgctgacttt
     2161 gtctatgcta ttggactaac tcaggacaat ttaccaaaaa tttctcaaaa caccagtctt
     2221 ctgacagatg aagaaaggca aaacctaaac caagcgaccg aagaaggcgt tcaattactg
     2281 attgccagca gtgaaaatct caagaaaaat cgctacacta tgctttcctt ggtcaattct
     2341 gctcgtaagc agttgttctt gtcggctcca agccttttta acgaaagtga aagtaaggaa
     2401 tctgcctatc ttcaagagtt gatccatttt ggatttaggc ggagagagaa gaggatgaat
     2461 cacaaaggac tgtctaagga ggatatgggg tcctatcaca gtcttttgtc tagtctggtt
     2521 gcctatcacc agcagggtga gatgagcgat actgagcaag atttgacttt tgtcaaggtt
     2581 ctgtcgcgtg tcataggtaa aaaactagat ctgcaaggtc tggaaaatcc agctatccca
     2641 accagtccaa gcagcaagac cttagccaag gacaccttgc aagctctcta tcctgccaaa
     2701 caggagtttt acctgtctac gtcgggtttg acagagtttt atcgcaatga atacagttat
     2761 ttcctacgct acgttttagg cttgcaggag gaattacgtt tgcgtcctga tgcccgtagt
     2821 cacgggaatt tcttgcatcg tatctttgaa cgcgccttac agttgcctaa tgaagattcc
     2881 tttgaccaac gtctagaaca agctattcaa gaaaccagtc aagaacgcga atttgaagct
     2941 atttatcaag aaagtttgga agcccagttt accaaggaag ttttgcttga tgttgcacgg
     3001 acgactggac atattctccg acacaatcca gccatcgaaa ccatcaaaga agaagcaaat
     3061 tttggtggaa aagaccaagc ctttattcaa ttagacaatg gacgcagtgt ctttgtacga
     3121 ggcaaggtgg accggattga ccgtttgaaa gctaatggag cgataggagt agtagactac
     3181 aaatccagtc tgactcagtt ccagtttcct catttcttta atgggctcaa ttctcagtta
     3241 ccaacctatc ttgctgccct aaaaagagaa gggaagcaga actttttcgg cgccatgtac
     3301 ttggaaatgg ctgaacctgt ccaatctctg atggcggtaa aaagtctggc aggagcagtg
     3361 gtagaagcca gcaaatctat gaaataccaa gggctcttct tggaaaaaga aagcagttat
     3421 ttaggcgaat tttataacaa aaacaaggct aatcaactga cagatgagga atttcagctc
     3481 ctactggact acaatgccta tctttacaag aaagctgctg agaagatttt agcaggccgg
     3541 ttcgccatca atccttatac tgaaaatggc agaagcattg ccccatacgt ccagcaacat
     3601 caggctatta caggctttga agccaattac catctgggcc aagcccgttt cctagaaaaa
     3661 ttggacctag ctgatggcaa gcgtctggtc ggagaaaaac tcaagcaagc ttggtttgaa
     3721 aaaataagag aggagttaaa tcgatgaagc ttattccctt tttaagtgag gaggagattc
     3781 aaaaactgca agaagcagaa gcaaattcga gcaaggaaca gaagaaaact gccgaacaaa
     3841 tcgaagctat ctacacttct ggtcagaata tcctggtctc agcatcggct ggttctggaa
     3901 agacctttgt catggcagag cgcattctgg accaattggc gcgtggtgtc gaaatttctc
     3961 aactctttat ctcaaccttt accgtcaagg ctgcaactga acttaaagaa cgtttagaga
     4021 aaaaaatcag caagaaaatc caagaaacag atgatgtcga tctcaaacaa cacttgggtc
     4081 gccagttggc agacctaccc aacgctgcca tcggaaccat ggactctttc acacaaaaat
     4141 tccttggcaa acatggttat ctgcttgata ttgcacctaa tttccgtatt ttacaaaacc
     4201 aaagcgagca acttcttctc gaaaacgaag tctttcatga ggtctttgaa gcgcattacc
     4261 aaggtaaaca gaaagagagc tttagtcatt tgctgaaaaa ctttgctggg cgtggcaagg
     4321 acgaacgggg tctgcggcag caagtctata aaatctatga cttcctccaa tccaccagta
     4381 atcctcaaaa gtggctgagt gaatctttcc tcaaaggctt tgagaaagct gattttacca
     4441 gtgaaaaaga aaaactgact gagcaaatca aacaagccct ctgggatttg gaaagctttt
     4501 tccgttacca tctggataac gatgccaagg agtttgcaaa ggctgcctat ttagaaaatg
     4561 ttcagttaat tctggatgaa attggctccc taaatcagga gttcgatagt caggcttatc
     4621 aggcagtact tgcgcgtgtt gtcgccatct ctaaggagaa aaacggtcgt gctctgacta
     4681 atgccagccg taaggctgat ttgaagcccc tggctgatgc ctacaacgaa gagagaaaga
     4741 cccagtttac taaactagga caattatcag accagatagc gattctcgac tatcaagaac
     4801 gttatcatgg agacacttgg aaactagcta aaaccttcca atctttcatg agcgattttg
     4861 tagaggctta tcgtcagaga aaacgacagg aaaatgcctt tgaattcgct gatatcagcc
     4921 attacaccat tgagatttta gaaaatttcc cacaagttcg tgagtcttat caggagcgct
     4981 tccatgaagt catggtcgat gagtatcagg ataccaacca tattcaagaa cggatgctgg
     5041 aattgttgtc taatggccac aatcgcttta tggtgggaga tatcaagcaa tccatctatc
     5101 gtttccgtca ggcagacccg cagattttca atgagaaatt ccaacgctat gcgcaaaatc
     5161 cccaagaagg caagctcatt ctcctcaagg aaaatttccg tagtagttca gaagtgctgt
     5221 cagcaaccaa tgatgtcttt gaacgtctca tggaccaaga ggtcggcgaa atcaactatg
     5281 ataacaagca ccagcttgtt tttgccaata ccaaactgac tcccaatcca gacaacaagg
     5341 cagaatttct cctctacgac aaggacgata caggtgagga agaagagagt caaacagaaa
     5401 cgaaactaac aggcgaaatg cgcttagtta tcaaggagat tctgaaactt catcaagaaa
     5461 aaggtgttgc ctttaaggaa attgcccttc tgacctccag ccgcagtcgt aatgaccaga
     5521 ttctcctcgc cctgtctgag tacgggattc ctgtcaaaac tgacggagag caaaacaatt
     5581 atctccaatc cctagaagtg caagtcatgc tagacactct tcgtgtcatt cacaatcccc
     5641 tgcaagacta tgccttggtt gcccttatga agtctccaat gtttggtttt gatgaggatg
     5701 agctagcacg tttgtccctt cagaaagcag aggataaagt ccacgaaaat ctctatgaga
     5761 aactggtcaa tgcacaaaaa atggcaagta gtcaaaaagg cttgattcac acagctctag
     5821 ctgaaaaact aaagcaattc atggatatcc tagcttcttg gcgcttgtat gccaaaaccc
     5881 actctctcta tgacttgatt tggaagattt acaacgaccg tttttattat gactatgttg
     5941 gggctttgcc gaatggtcct gctaggcagg ccaatctcta tgccctagca ctgcgtgctg
     6001 atcaatttga aaagagcaat ttcaaaggtt tgtcgcgttt tattcgtatg attgaccaag
     6061 tcttagaagc ccagcacgat ttggcaagcg tggccgtcgc accgccaaaa gatgcagtag
     6121 agctcatgac catccacaag agtaaagggc tggagtttcc ttacgtcttt atcctcaata
     6181 tggatcaaga tttcaacaag caagactcta tgtcagaagt cattctcagt cgtcagaatg
     6241 gtcttggtgt caaatatatt gccaagatgg agacaggggc agtagaagac cactatccta
     6301 aaaccatcaa actctccatt cctagtctga cctataggca gaacgaagag gaattacagc
     6361 tagcaagcta ttctgagcag atgcgtttgc tgtatgttgc tatgacgcgg gctgagaaaa
     6421 agctctatct tgtcggcaag ggttctcgtg aaaagctgga agtcaagcaa tacccagcag
     6481 ccaaaaatgg gaaactaaat agcaatacta gactgcaagc acggaatttc caagattggc
     6541 tttgggctat cagtaaagtg tttactaagg acaagctcaa ctttagttat cgttttattg
     6601 gcgaagatca gttgaccaga gaagctatcg gagagttgga aaccaagagt cctctccaag
     6661 atagctccca agcagacaat cgtcagtcag ataccatcaa agaagctctg gaaatgctga
     6721 aggaggtgga agtttataat actcttcacc gcgcagctat tgaacttcct agtgttcaaa
     6781 ccccaagtca aatcaagaaa ttctacgaac cagttatgga tatggaaggt gtcgagattg
     6841 ctggtcaagg tcagtcagta ggcaagaaaa tcagcttcga tttgccagat ttttcaacca
     6901 aagaaaaggt aactggagct gagattggta gtgctactca cgaactcatg cagagaattg
     6961 acctcagcca gcaactaacc cttgctagcc taacagaaac actcaaacaa gttcaaacta
     7021 gccaagctgt cagagacaag atcaatcttg ataaaattct tgctttcttt gacacagtac
     7081 tcggtcagga aattcttgct aataccgacc atctctatcg cgagcaacct ttctccatgc
     7141 tcaaacgaga ccaaaagagt caggaagact ttgttgtccg tggtatcctt gatggctatc
     7201 tgctttacga aaacaaaatt gttctgttcg actacaagac agaccgctat gatgaaccaa
     7261 gtcaactcgt agaccgctat cgtggtcagt tagctctata cgaagaggct ttatcacgag
     7321 cctattcgat tgaaaatatt gaaaaatact tgattttact cggtaaagac gaggttcaag
     7381 ttgtaaaagt ataacttata ctctttgaaa atctcttcaa accacgtcag cttcgccttg
     7441 ctgtatatat ggttactgac ttcgtcagtt ctatccacaa cctcaaaaca gtgttttgag
     7501 ctgacttcgt cagttctatc tacaacctca aaacagtgtt ttgagctgat tgcggctagc
     7561 tttctagttt gctctttgat ttttattgag tattagaaag gagacctcat gacacttcca
     7621 gttagaaaat ccctgcacga tgcagtttta caggcttcga aagcggatac ttgggaacaa
     7681 gctaccaagg aatggaatga agtttccttg atttttaacg gtatcggccg tagcaattgt
     7741 gtctgtggaa atgccatcaa atacgcttat gaactcttta acggtgtcac aggccaacgc
     7801 ctctttccaa ttggtagcta ctgtgttcgt cattttcatc gattgtccct tgaccagcaa
     7861 ttggaagagg aagaaaaact gctcagaaag gttgaaaacc taaccagaaa agctcagaaa
     7921 aaggaaaaaa tcaaggtcaa taaaagtgac tttgacgagc gacttctaaa atggctctgg
     7981 gaaaaaggtg ttttcaaacc caatcgtggc aatcaatttg cgcctgagag agactaccag
     8041 cttttcctag aagtctttca gggaggaagt tggaccaagg cggaaccaaa gaaaaaggct
     8101 cggatggaag aagtccttga aaagtgtatc aaaccctttt tacttgggaa atcggatgac
     8161 caactctacc ttgtcaagct aggcaaggag aaaattgact acgaacaaga actccgtatc
     8221 caggcagaga aagaacgcaa gaagagggat aaaatcgcca agcaatatgc agacaatctg
     8281 gttctagcca tgggacccgc agagcgtgct tatcaagatt actttggctt tacagagacc
     8341 ctgactcaag aagaacgcaa gtgggaaaaa attctttttg gtaaaaatag agcagaacgg
     8401 gctatcaagg ccaaacaata ccaaaaagag ctggaaaaag accaacgaat tgccagtcag
     8461 gatccaattg aaagaaaaca gaagcagact tggctcctca attcctattt tcgtgagctt
     8521 cctgaagaaa aagctcgatt ttctaggctc ttattagaat atcgaaaaag tggtgaagta
     8581 cccttttcaa ctgaatacct gtccgatcat ctcatcgact ttttctataa aatgaaagcc
     8641 tttgaatttg aaatcgcacc agaacaagtc cgagattttc taaaaaaaag cctgcaggaa
     8701 gaccatcgct catcagcaca aggaagctgg atagaaggaa ttctcctcaa ctgcctcaaa
     8761 ccatttttag aacgattagt gatatgagta acacctaccg tgtaaatttc atggtaggtg
     8821 ttattgtacc cccaaataat ataaaacaaa gtatgaaagc gcatctcaat tttaagactt
     8881 ttttgtaaat taagagtata attaaggtat actgcctttt ctatagataa tagataatac
     8941 actaatataa taaaggtctt tgtaacatat ataaatttta tttcaaggag gaataatgga
     9001 aaagtatttt ggtgaaaaac aagagcgttt ttcatttaga aaattatcag taggacttgt
     9061 atctgcaacg atttcaagtt tattttttat gtctgtatta gctagttcat ctgtggatgc
     9121 tcaagaaact gcgggagttc actataaata tgtggcagat tcagagctat catcagaaga
     9181 aaagaagcag cttgtctatg atattccgac atacgtggag aatgatgatg aaacttatta
     9241 tcttgtttat aagttaaatt ctcaaaatca actggcggaa ttaccaaata ctggaagcaa
     9301 gaatgagagg caagccctag ttgctggtgc tagcttagct gctctgggaa ttttaatttt
     9361 tgctgtttcc aagaaaaagg ttaagaataa aacggtatta catttagtat tggttgcggg
     9421 aatgggaaat ggtgtcttag tttcagtcca tgctttagaa aatcatcttt tgctaaatta
     9481 caatacggac tatgaattga cctctggaga aaaattacct cttcctaaag agatttcagg
     9541 ttacacttat attggatata tcaaagaggg aaaaacgact tctgattttg aagtaagtaa
     9601 tcaagaaaaa tcagcagcca ctcctacaaa acaacaaaag gtggattata atgttacacc
     9661 aaattttgta gaccatccat caacagtaca agctattcag gaacaaacac ctgtttcttc
     9721 aactaagccg acagaagttc aagtagttga aaaacctttc tctactgaat taatcaatcc
     9781 aagaaaagaa gagaaacaat cttcagattc tcaagaacaa ttagccgaac ataagaatct
     9841 agaaacgaag aaagaggaga agatttctcc aaaagaaaag actggggtaa atacattaaa
     9901 tccacaggat gaagttttat caggtcaatt gaacaaacct gaactcttat atcgtgagga
     9961 aactatagag acaaaaatag attttcaaga agaaattcaa gaaaatcctg atttagctga
    10021 aggaactgta agagtaaaac aagaaggtaa attaggtaag aaagttgaaa tcgtcagaat
    10081 attctctgta aacaaggaag aagtttcgcg agaaattgtt tcaacttcaa cgactgcgcc
    10141 tagtccaaga atagtcgaaa aaggtactaa aaaaactcaa gttataaagg aacaacctga
    10201 gactggtgta gaacataagg acgtacagtc tggagctatt gttgaacccg caattcagcc
    10261 tgagttgccc gaagcagtag taagtgataa aggcgtacca gaagttcaac cagcgttatc
    10321 ggaagcagtc gtaaccgaca aaggtgagcc cgctgtccaa ccagagctac cggaagcagt
    10381 tgtaagtgat aaaggtgaac cagcagtcca accagagcta ccggaagcgg ttgtgactga
    10441 caaaggtgat ccagagcagg tagaaccgct accagaatat acaggagtac aagctggagc
    10501 tattgttgaa cctgaaaaag ttgaaccgga atatgctgga gtacaagctg gcgctattgt
    10561 tgaaccagag caggtagcac cactaccaga atacacaggg gtgcaagccg gagcgatagt
    10621 cgagccagag aaagtagaag caccgaagga atacacagga gtgcaggctg gagcgatagt
    10681 cgaaccagag aaggtagaag caccgaagga atacacagga gtgcaagccg gagcaatagt
    10741 agaaccagaa aaagtagaac catcaaaaga atacacaggg gtgcaggctg gcgctattgt
    10801 tgaaccagag cagatagcac cactaccaga atacacaggg gtgcaagccg gagcgatagt
    10861 cgagccagag aaagtagaag cactgaaaga atatactggt aaaatcgaac aacctagtgc
    10921 agaagatact aaaccaaata atgaaaatac taatacacca gaagaaatga gtattcagaa
    10981 aaaatctagt gcattaatta atatgaactt tattacagat tcgtcgaagg ttactggagt
    11041 aggatcagct acttttattg caccaaatgt acttttaaca gtagcacata atttcattaa
    11101 taattctact gataatacta ctggcgaatt tagaggtgat aaatctaaaa acgtatatga
    11161 gtgggtgact cctgatggac aaaaaggaac atttactgct aacaatattc atttttataa
    11221 taaaaaagat tatccaaaag gatttatcta tgatttagca gtgattaagc tacctgaaac
    11281 aactggcaga gaacatgtag aattagttaa aaattattcg aaagtaaatc ttaatgacaa
    11341 actaaatgtt catggatatc cagctgggaa atatacgcac ttaaaagatg ctacggtaga
    11401 aatggaacaa gaatatgcga ataacaccta cggtgttcaa tatcaaggtg gaaatcctgg
    11461 tatgagtggt ggaggaatat ttaatgctaa tggtgaagtt attggtgtgc atcaaaatgg
    11521 agcacaaaat cgctcaggcg gattgatttt atctcctaca caattagctt ggattaagag
    11581 tattatagca ggtaatgaaa ttccaccagt atacgatgaa ctttatcgtc ataaagatga
    11641 gaaaaaagat gacgctaaag atgaaaaaga agttattaag aaattagaac ttagaaatat
    11701 atcttctgta gaactatatt caaaagatgg taataagtat cgacatgtaa cttcacttgc
    11761 ttctttacca agtaatgcag aaaattactt tatgaaagtt aaatcagaga actttaaaga
    11821 tgtgatgcta ccagttacaa gcattactaa tgatactaaa gataatagag atgtttataa
    11881 gatagtagca agtgcaaata gtctgataca acatgaaaat aataatgtac tagaaaatta
    11941 tacatactat ttaccaaaaa ctcagcaaag tgaaactggg gtatatacat catttaaaaa
    12001 tttagtagat gcaatgaata gcaatcctaa tggcacattc cgtttaggag caactatgga
    12061 tgctcgtgaa gttgaacttc cagatggtca agaaagttat gtgaataatg tattccatgg
    12121 aatattagta ggaacaaata atgagaaata ttatgctatt tataatttga aaaaaccatt
    12181 atttggggaa ttaaatggtg ctacagtaga aaaactttca ctaaaagatg ttaatatttc
    12241 cgcaaaggac gatactgcaa cacttgcgaa agaagcaaat aacaatactc atattgataa
    12301 cgttcatgct gatggagcga tagctgggga acgtagcata ggaggattag tatcacaagt
    12361 taataattct actatttcta acagtagcta tacaggtaga ataactaata catataaaac
    12421 agttgctagt tatcaaatcg gaggtttagt aggcaaactt tctggtccga ggggattaat
    12481 agataagtcg ttcgcatcaa tcgatttatc ttcaaatgca acacaaggag accagtctat
    12541 tggtggaata gttggtgcag tagaaaatag tgcgcttatt agtaatagtt atgctgaagg
    12601 aaatctaaat aatgttcaac gttttgcaaa cgttggtgga gtagttggta atctttggga
    12661 tccggttgga ggattagaaa aatccggtcg actttctaat gtactaagcg atgttaatgt
    12721 aacgaatggt aatgctattg caggttataa ttttaatggt ataaaagcaa atggcacata
    12781 cagtaataaa aataataagg ttgtgaacgt agtacaagaa gatgatgaaa tcttaactaa
    12841 ggattctact gttcaaagag gagaagtatt agaagatgca caaataaaag agaaaaaagc
    12901 tacttttgta tctaaaaata ctattaaaac agaa
//
LOCUS       DBEJAU010000053        12719 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC323 isolate 683620
            SAMN38261939-rid24807223.denovo.053, whole genome shotgun sequence.
ACCESSION   DBEJAU010000053 DBEJAU010000000
VERSION     DBEJAU010000053.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261939
            Sequence Read Archive: SRR26833919
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 12719)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12719)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576303.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576303.1
            Genome Coverage       :: 154x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/19/2025 01:05:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,121
            CDSs (total)                      :: 2,078
            Genes (coding)                    :: 1,943
            CDSs (with protein)               :: 1,943
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 36
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 72 of 135
            Pseudo Genes (incomplete)         :: 63 of 135
            Pseudo Genes (internal stop)      :: 51 of 135
            Pseudo Genes (multiple problems)  :: 46 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12719
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261939-rid24807223.denovo.053"
                     /strain="GPSC323"
                     /isolate="683620"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            complement(1..384)
                     /locus_tag="ACL29Z_001746"
                     /pseudo
     CDS             complement(1..384)
                     /locus_tag="ACL29Z_001746"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus and C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(446..895)
                     /locus_tag="ACL29Z_001747"
     CDS             complement(446..895)
                     /locus_tag="ACL29Z_001747"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine/serine exporter family protein"
                     /protein_id="HGR0070012.1"
                     /translation="MTLTTFLLQAVASFLAIITFLIVLNVQRSMLLPGGILGMTVWLI
                     YLLLKEPTNVIVATFIAAIIGSCVSQILSILYKTPAVVFILAILAPLVPGYLSYRTTA
                     FFVTGDYNKALASATLVVMLALVISIGMASGTVILRLYHYIKTHRVS"
     gene            complement(897..1655)
                     /locus_tag="ACL29Z_001748"
     CDS             complement(897..1655)
                     /locus_tag="ACL29Z_001748"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000392945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine/serine exporter family protein"
                     /protein_id="HGR0070013.1"
                     /translation="MEESKELNAVIDVIMLAGTILLKSGSEIHRVEDTMIRIAHSQGI
                     VDCNVLAMPAAIFFSIENTNISRMKRVTSSSYNIEKVCDVNQISRQLVGGQIDLETAF
                     KQLTALQAQPLPYTKLQVTLAATFSAPFFSVMFSGNIYDALGAGVATLFGFAFSLYVE
                     KFIRIPFVTAFAGAFVFGIIAQFWARYTGFPSTADLIIAGAVMPFVPGIALTNAVRDI
                     MTNHINSGMSKMFESLLITLALGAGTSVALVLMN"
     gene            complement(1770..3749)
                     /gene="stkP"
                     /locus_tag="ACL29Z_001749"
     CDS             complement(1770..3749)
                     /gene="stkP"
                     /locus_tag="ACL29Z_001749"
                     /EC_number="2.7.11.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000614538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine/threonine-protein kinase StkP"
                     /protein_id="HGR0070014.1"
                     /translation="MIQIGKIFAGRYRIVKQIGRGGMADVYLAKDLILDGEEVAVKVL
                     RTNYQTDPIAVARFQREARAMADLDHPHIVRITDIGEEDGQQYLAMEYVAGLDLKRYI
                     KEHYPLSNEEAVRIMGQILLAMRLAHTRGIVHRDLKPQNILLTPDGTAKVTDFGIAVA
                     FAETSLTQTNSMLGSVHYLSPEQARGSKATVQSDIYAMGIIFYEMLTGHIPYDGDSAV
                     TIALQHFQKPLPSVIAENPSVPQALENVIIKATAKKLTNRYRSVSEMYVDLSSSLSYN
                     RRNESKLIFDETSKADTKTLPKVSQSTLTSIPKVQAQTEHKSIKNPSQAVTEETYQPQ
                     APKKHRFKMRYLILLASLVLVAASLIWILSRTPATIAIPDVAGQTVAEAKATLKKANF
                     EIGEEKTEASEKVEEGRIIRTDPGAGTGRKEGTKINLVVSSGKQSFQISNYVGRKSSD
                     VIAELKEKKVPDNLIKIEEEESNESEAGTVLKQSLPEGTTYDLSKATQIVLTVAKKAT
                     TIQLGNYIGRNSTEVISELKQKKVPENLIKIEEEESSESEPGTIMKQSPGAGTTYDVS
                     KPTQIVLTVAKKVTSVAMPSYIGSSLEFTKNNLIQIVGIKEANIEVVEVTTAPAGSAE
                     GMVVEQSPRAGEKVDLNKTRVKISIYKPKTTSATP"
     gene            complement(3746..4486)
                     /locus_tag="ACL29Z_001750"
     CDS             complement(3746..4486)
                     /locus_tag="ACL29Z_001750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004722 - protein serine/threonine
                     phosphatase activity [Evidence IEA];
                     GO_process: GO:0006470 - protein dephosphorylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Stp1/IreP family PP2C-type Ser/Thr phosphatase"
                     /protein_id="HGR0070015.1"
                     /translation="MEISLLTDVGQKRTNNQDYVNHYVNRAGRTMIILADGMGGHRAG
                     NIASEMAVTDLGVAWVDTQIDTVNEVREWFAHYLEIENQKIHQLGQDEAYRGMGTTLE
                     VLAIIDNQAIYAHIGDSRIGLIRGEEYHQLTSDHSLVNELLKAGQLTPEEAEAHPQKN
                     IITQSIGQKDEIQPDFGTVILESGDYLLLNSDGLTNMISGSEIRDIVTSDIPLADKTE
                     TLVRFANNAGGLDNITVALVSMNEEDAE"
     gene            complement(4501..5814)
                     /gene="rsmB"
                     /locus_tag="ACL29Z_001751"
     CDS             complement(4501..5814)
                     /gene="rsmB"
                     /locus_tag="ACL29Z_001751"
                     /EC_number="2.1.1.176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255437.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0008168 - methyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0001510 - RNA methylation [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (cytosine(967)-C(5))-methyltransferase
                     RsmB"
                     /protein_id="HGR0070016.1"
                     /translation="MTKVETARSLALAVLEDVFVNQAYSNIALNKHLKGSQLSAADKG
                     LVTELVYGTVARKLTLEWYLSHFIEDRDQLDSWLYVLLLMSAYQLRYLDKIPDHAVVN
                     EAVELAKLRKKGSEKLVNAVLRRILREGWPDIANIKRKNKRDSIAYSLPVWLVTKLKE
                     EYGEERAKAIFESLLVRNKASIRVTDLSRKEEIQALLEANNSLLATTGLVKEQGHFAG
                     HNLFADGAITIQDESSQLVAPTLDLQGDERVLDACAAPGGKTAHIASYLTTGQVTALD
                     LYDHKLDLIQENAQRLGVADRVQTQKLDARKVHEFFDQDSFDKILVDAPCSGIGLLRR
                     KPDIKYNKETADFASLQEIQLEILGSVCQILGKGGIITYSTCTIVSEENFQVVKAFLE
                     SHPEFEQVKLEHECKDIMKDGCILITPELYGSDGFFISQFRKISD"
     gene            complement(5807..6742)
                     /gene="fmt"
                     /locus_tag="ACL29Z_001752"
     CDS             complement(5807..6742)
                     /gene="fmt"
                     /locus_tag="ACL29Z_001752"
                     /EC_number="2.1.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000163675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004479 - methionyl-tRNA formyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0071951 - conversion of methionyl-tRNA to
                     N-formyl-methionyl-tRNA [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="methionyl-tRNA formyltransferase"
                     /protein_id="HGR0070017.1"
                     /translation="MTKLIFMGTPDFSATVLKGLLTDDRYEILAVVTQPDRAVGRKKV
                     IQETPVKQAAKEAGLSIYQPEKLSGSPEMEDLMKLGADGIVTAAFGQFLPSKLLDSMD
                     FAVNVHASLLPRHRGGAPIHYALIQGDEEAGVTIMEMVKEMDAGDMISRRSIPITDED
                     NVGALFEKLALVGRDLLLDTLPAYIAGDIKPEPQDTSQVTFSPNIKPEEEKLDWNKTN
                     RQLFNQIRGMNPWPVAHTFLKGDRFKIYEALPVEGQGNPGEILSIGKKELIVATAEGA
                     LSLKQVQPAGKPKMDIASFLNGVGRTLTVGERFGD"
     gene            complement(6755..9151)
                     /locus_tag="ACL29Z_001753"
     CDS             complement(6755..9151)
                     /locus_tag="ACL29Z_001753"
                     /EC_number="3.6.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001162119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003678 - DNA helicase activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA];
                     GO_process: GO:0032508 - DNA duplex unwinding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="primosomal protein N'"
                     /protein_id="HGR0070018.1"
                     /translation="MALAKIIVDVPLMQTDQPYSYRIPEEFEGMLEVGMRVHVPFGKG
                     NRLIQGIVLGLKSQSDGEEMEQDLKDIAEVLDFSPVLTPEQLWLAEELRKSVFSYKIS
                     ILKAMLPGFLNSSYDKILYPLEGLSQEERVRLFGSEDSLAFSSLDLAKQAEMMRLTRK
                     GLLGLEYQAVDQKKVKTQSWYEVDHAQLEGVEISTRAKKKLELRDYLLSHPESASLAS
                     LLESYSREQVNFFVDQGAVTIVQKEVQRSAAYFEGIEASRPLELNPEQRQARDAVVSS
                     IGSSQPPFLLQGITGSGKTEVYLQIIQGALDKGKTAILLVPEISLTPQMTERFIARFG
                     DKVAILHSGLSNGEKYDEWRKVERGDAQVVVGARSAIFAPLKNLGVMIIDEEHEAAYK
                     QDSNPRYHAREVAILRAQYNQATLVLGSATPSLESRARAGKGVYQHLRLTQRANPLAT
                     IPEVQVIDFRDYIGQNETSNFTPPLLEAIQDRLVKKEQVVLMLNRRGYSSFVMCRECG
                     TVDTCPNCDISLTLHMDTKTMNCHYCGFSKDIPQVCPNCKSRSIRYYGTGTQKAYDEL
                     AELFPQARILRMDVDTTRKKGSHQALLDQFGRGEADILLGTQMIAKGLDFPNVTLVGV
                     LNADTALNLPDFRSSERTFQLLTQVAGRAGRAEKAGQVLIQSYNPQHYAIRFAKDQDY
                     EGFYAYEMGIRRQLGYPPYYFTIGITLSHKKEEEVVKRAYEVMNILRSSLSETSSILG
                     PTPKPIARTHNLYHYQILIKYRLEDELGPTLNQVLALTQERENSELRLSIDHEPQQFL
                     "
     gene            complement(9217..9531)
                     /gene="rpoZ"
                     /locus_tag="ACL29Z_001754"
     CDS             complement(9217..9531)
                     /gene="rpoZ"
                     /locus_tag="ACL29Z_001754"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001817694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003899 - DNA-directed 5'-3' RNA
                     polymerase activity [Evidence IEA];
                     GO_process: GO:0006351 - DNA-templated transcription
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit omega"
                     /protein_id="HGR0070019.1"
                     /translation="MMLKPSIDTLLDKVPSKYSLVILEAKRAHELEAGAPATQGFKSE
                     KSTLRALEEIESGNVTIHPDPEGKREAVRRRIEEEKRRKEEEEKKIKEQIAKEKEDGE
                     KI"
     gene            complement(9556..10182)
                     /gene="gmk"
                     /locus_tag="ACL29Z_001755"
     CDS             complement(9556..10182)
                     /gene="gmk"
                     /locus_tag="ACL29Z_001755"
                     /EC_number="2.7.4.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000775037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004385 - guanylate kinase activity
                     [Evidence IEA];
                     GO_process: GO:0006163 - purine nucleotide metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="guanylate kinase"
                     /protein_id="HGR0070020.1"
                     /translation="MADRGLLIVFSGPSGVGKGTVRREIFESSENQFQYSVSMTTRAQ
                     RPGEVDGVDYFFRTREEFEELIRQGQMLEYAEYVGNYYGTPLTYVNETLDKGIDVFLE
                     IEVQGALQVKKKVPDAVFIFLTPPDLDELQDRLVGRGTDSAEVIAQRIEKAKEEIALM
                     REYDYAIVNDQVPLAAERVKCVIEAEHFCVDRVIGHYQEMLPKSPTTR"
     gene            complement(10312..11925)
                     /locus_tag="ACL29Z_001756"
     CDS             complement(10312..11925)
                     /locus_tag="ACL29Z_001756"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520539.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease Y"
                     /protein_id="HGR0070021.1"
                     /translation="MEIMSLAIAVFAVIIGLVIGYVSISAKMKSSQEAAELMLLNAEQ
                     EATNLRGQAEREADLLVNEAKRESKSLKKEALLEAKEEARKYREEVDAEFKSERQELK
                     QIESRLTERATSLDRKDDNLTSKEQTLEQKEQSISDRAKNLDAREEQLEEVERQKEAE
                     LERIGALSQAEARDIILAQTEENLTREIASRIREAEQEVKERSDKMAKDILVQAMQRI
                     AGEYVAESTNSTVHLPDDTMKGRIIGREGRNIRTFESLTGVDVIIDDTPEVVTLSGFD
                     PIRREIARMTMEMLLKDGRIHPARIEELVEKNRQEIDNKIREYGEAAAYEIGAPNLHP
                     DLMKIMGRLQFRTSYGQNVLRHSIEVAKLAGIMASELGENAALARRAGFLHDIGKAID
                     HEVEGSHVEIGMELARKYKEPPVVVNTIASHHGDVEAESVIAVIVAAADALSAARPGA
                     RSESLESYIKRLHDLEEIANGFEGVQTSFALQAGREIRIMVNPGKIKDDKVTILAHKV
                     RKKIENNLDYPGNIKVTVIRELRAVDYAK"
     gene            complement(12116..12370)
                     /locus_tag="ACL29Z_001757"
     CDS             complement(12116..12370)
                     /locus_tag="ACL29Z_001757"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006152757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0008219 - cell death [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Txe/YoeB family addiction module toxin"
                     /protein_id="HGR0070022.1"
                     /translation="MLLKFTEDAWADYCYWQNQDKKTLKRINKLIKDIQRDPFTGIGK
                     PEPLKYDYQGAWSRRIDAENRLIYMMDGDSVAFLSFKDHY"
     gene            complement(12374..12628)
                     /locus_tag="ACL29Z_001758"
     CDS             complement(12374..12628)
                     /locus_tag="ACL29Z_001758"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000388574.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0110001 - toxin-antitoxin complex
                     [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0097351 - toxin sequestering activity
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA];
                     GO_process: GO:0045927 - positive regulation of growth
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system Phd/YefM family
                     antitoxin"
                     /protein_id="HGR0070023.1"
                     /translation="MEAVLYSTFRNHLKDYMKKVNDEFEPLTVVNKNPDEDIVVLSKS
                     EWDSIQETLRIAQNKELSDKVLRGMAQVRAGSTQVHVIEE"
BASE COUNT         3396 a         3037 c         2498 g         3788 t
ORIGIN      
        1 ccttgataac cactgtcagc caagatttta ccagcttgtc cgatatttct gcaactcatt
       61 ttgaacaact tcatatcatg acaatagttc acagtgatat ccaaagaaac aattctccct
      121 tgacttgtga caatcgcttg agtcttcata gcgtgaaatt tctttttacc agaatcattc
      181 gctaattctt tttttagggc gattgatttt tactttcgtc gcatcaatca ttaccgtgtc
      241 ctcagaactg agaggagttc ttgaaatcgt aacaccactt tgaacaagag ttacttcaac
      301 ccattggctc cgacggagta agttgctttc gtggatacca aaatcagccg caatttcttc
      361 ataagttcga tattctcgca catatagaaa gcgttgttaa tttatttatc tcatttttca
      421 gaaaattctt ttatttctgt aaagtctacg atactcgatg tgtttttata taatgataca
      481 gtctgagaat cactgttccg ctagccattc caatagagat taccagagcc aacatgacaa
      541 ccaaggtcgc acttgccagt gctttattat agtcccctgt cacaaaaaag gcagttgttc
      601 ggtaggagag ataacctgga accagcggtg ccaaaatggc caagataaag accacagcag
      661 gtgtcttata aagaatactt aaaatctggc tgacacaaga accaataatg gctgcaatga
      721 aggtagctac aatgacattg gtcggttcct tgagcaagag atagattagc cagacagtca
      781 tgcccaaaat ccctccaggc aagagcatag accgttgcac attgagtacg attaaaaaag
      841 tgataatggc aagaaaactt gctactgctt gtaataaaaa ggttgttagt gtcatattag
      901 ttcatcaata ccaaggcgac agaagttcct gcccctaaag cgagggtaat gagcagggat
      961 tcaaacatct tactcatacc agagtttatg tggttggtca taatatcacg gaccgcattg
     1021 gtcaaggcaa tacctggtac aaacggcatg accgcaccag ctataatcaa atctgccgtt
     1081 gaaggaaaac ctgtgtagcg agcccaaaac tgggcaatta tcccaaagac aaaggctcca
     1141 gcaaaggctg tcacaaaggg aattcggata aatttttcca catagaggga aaaggcaaaa
     1201 ccaaataagg tcgccactcc tgccccaagt gcgtcgtaga tatttccgct aaacataact
     1261 gaaaagaaag gagcactaaa ggtcgcagcc agagttacct gcaacttagt atagggaagg
     1321 ggttgagctt gcaaggccgt caattgctta aaggctgttt ctaagtcaat ctgcccccca
     1381 actagctgac gagaaatctg gttcacatcg cagacttttt cgatgttata agaagaggag
     1441 gtcacgcgct tcatgcgcga aatattggta ttttcaatag agaaaaagat agcggcaggc
     1501 atggcaagga cattgcaatc cacaatcccc tgcgaatgcg cgattcgaat catggtatct
     1561 tctacacgat ggatttctga gccactttta aggagaatag tccccgctag cataatcaca
     1621 tcaatgacgg catttaattc ttttgattct tccatgcttt cctcctttta tcaactccct
     1681 ctattctatc acaaatctgg actcaaaaaa aatctttgcc atgaaatcat gacaaagatt
     1741 gattactcat tttgattatc catctgcttt taaggagtag ctgaagttgt tttaggtttg
     1801 tagattgaaa tcttgactct agtcttattt aggtctacct tttcacctgc tctaggactt
     1861 tgttcaacaa ccatgccttc tgcactacct gcaggcgctg tcgtcacttc tacaacttct
     1921 atattagctt ccttaatccc aacaatttga atcaaattgt tcttagtaaa ctccaagcta
     1981 gaaccaatgt aactcggcat ggcaacactt gtaacttttt tagctactgt caagacaatt
     2041 tgagtaggtt tactcacatc ataagtcgtt ccggcacctg gactttgttt cataatcgtt
     2101 cctggttcgc tttcgctgga ctcttcttcc tctatcttaa tcaaattctc aggaaccttc
     2161 ttctgcttga gttctgagat tacttctgta gagttccgtc caatatagtt ccctaattga
     2221 atcgtcgtag cttttttagc tactgtcaaa acaatttgag ttgccttgct caagtcatag
     2281 gtcgtacctt ctggtagact ttgcttcagg accgttccag cctcactctc attcgactct
     2341 tcttcctcaa ttttaatcaa attatctgga acttttttct cttttaattc cgcaatgaca
     2401 tcagaggatt tccgaccgac ataattacta atttggaaag attgcttgcc tgatgagaca
     2461 accaaattga ttttcgttcc ttcttttcga ccagttccag cgccaggatc tgtacggata
     2521 atccgccctt cttccacctt ttcactagcc tctgtcttct cctcaccaat ctcaaaattg
     2581 gcttttttga gcgttgcctt ggcctctgca actgtctgac ctgccacatc tggaatggca
     2641 atggttgcag gagttctgga taatatccaa ataagagaag ctgccaccaa tacaaggctg
     2701 gccaacaaaa tcaggtaacg catcttaaat ctatgttttt tcggtgcttg tggttggtaa
     2761 gtttcctctg tcacagcctg gcttgggttt ttgattgatt tgtgttctgt ctgcgcttga
     2821 accttaggaa tagatgtcaa ggtactctga gaaaccttcg gcaaggtctt ggtatctgcc
     2881 ttgctcgttt catcaaagat taacttactt tcatttctac gattgtagga caagctacta
     2941 gacaagtcca catacatctc tgaaaccgag cggtagcgat tggtcaactt tttagcagtt
     3001 gccttgataa taacattttc taaagcctga ggtacagatg gattttctgc aataacggac
     3061 ggcaggggtt tctgaaaatg ctggagggca atggtcaccg cgctatcccc gtcataaggg
     3121 atatggcctg tcaacatctc atagaaaata atccccatgg catagatatc actctgcaca
     3181 gtcgccttcg aaccacgcgc ctgctctggt gacaagtaat gaactgagcc caacatcgag
     3241 ttagtctggg tcagacttgt ctctgcaaag gctacagcaa tcccaaagtc tgtgaccttg
     3301 gcagtcccat ctggtgtcaa aaggatattt tgaggtttca agtccctgtg aacaattcct
     3361 cgagtatggg ccaagcgcat agccaagaga atttgtccca tgatacggac ggcttcttca
     3421 ttagaaagag gataatgttc cttgatatag cgtttgaggt ctagtccagc aacatactcc
     3481 attgcaagat actgttgacc gtcttcctca ccaatatctg ttatccgaac gatatgagga
     3541 tggtctagat ctgccatagc tctcgcttca cgctgaaaac gagctacagc tatcgggtcc
     3601 gtctggtagt tggtcctcag aaccttcact gccacttctt ccccatctaa gattaagtct
     3661 ttggctaggt agacatccgc catgcctcct cgaccaatct gtttgacaat ccgatagcgt
     3721 ccggcaaaaa tcttgccgat ttggatcatt ctgcatcctc ctcgttcata gaaacaaggg
     3781 caaccgtaat gttgtctaaa cctcctgcat tgttagcaaa acgaacaagt gtctccgttt
     3841 tatctgctaa aggaatatca ctggttacaa tatcacgaat ctcactgcct gaaatcatgt
     3901 tggtcaagcc gtcactattg agcaagagat agtcacctga ctcaaggata actgtcccaa
     3961 aatcaggctg aatttcatct ttttgcccaa tagactgggt gataatattt ttttgcggat
     4021 gagcttctgc ctcttctggt gtcaattgac cagccttgag caattcatta accaaggaat
     4081 gatcgctcgt caactgatgg tattcttctc cacgaatcaa gccgatacgc gaatcaccaa
     4141 tatgagcata gatagcctga ttatcaataa tagcaaggac ttccaaagta gttcccatgc
     4201 ctctgtaagc ttcatcctga ccaagctggt gaatcttttg attttcaatt tctaggtaat
     4261 gggcgaacca ttcacgcact tcattgactg tatcgatctg ggtatcaacc caagctacac
     4321 ccaggtctgt caccgccatt tcactagcga tattccctgc gcgatgacct cccatcccat
     4381 cagctaaaat aatcatggta cgtccagctc tattgacata gtggttgaca tagtcttggt
     4441 tatttgttcg tttctgacca acatctgtta ataatgaaat ttccatgtgt cagttccttc
     4501 ctaatccgat atcttgcgaa attgactgat gaagaatcca tcacttccat acaattcagg
     4561 tgtaatgagg atacagccgt ctttcatgat atccttacat tcatgttcta gttttacctg
     4621 ctcgaactcg ggatgactct ctaaaaaggc cttaacgact tgaaaattct cctctgagac
     4681 gatagtgcag gtgctataag ttattatacc acctttgcct agtatttgac aaacactacc
     4741 taatatttct aactgaattt cctgcaagga cgcgaaatct gccgtttctt tattgtattt
     4801 gatatctggt tttcggcgca aaagaccgat tcctgaacaa ggagcatcca ccaaaatctt
     4861 atcaaaggaa tcctggtcaa aaaactcatg cacctttctg gcatccaatt tttgagtttg
     4921 aacccgatct gcaactccca gacgttgggc attttcttga attaaatcca acttgtggtc
     4981 gtacaagtcc agagcagtaa cctgacctgt cgtaagataa gaggctatat gggctgtttt
     5041 cccacctgga gccgcacagg catcaagcac tcgctcatca ccttgtaaat caagcgtcgg
     5101 agcaaccagc tgactggact cgtcttggat ggtaatggct ccatccgcaa acaaattatg
     5161 ccctgcaaaa tgcccctgct ccttaaccag accagtggtt gctaaaaggg aattattcgc
     5221 ctccaacaag gcttggattt cctcttttcg acttaggtct gttacacgaa tactagcttt
     5281 gtttcgcact aacaggcttt caaagatggc ttttgctctc tcctctccgt attcttcctt
     5341 gagtttggta actagccaaa ctgggagaga ataggcaatg gagtcacgct tgttttttcg
     5401 cttgatgtta gcaatatctg gccagccttc acgcaagata cggcgaagga cagcgttgac
     5461 caatttttca ctgccttttt tacggagttt ggccaattcc actgcttcat tgaccacagc
     5521 atgatctgga atcttgtcca aatagcggag ttggtaggca ctcatgagaa gaaggacata
     5581 gagccagctg tctaactggt ctctgtcttc gataaagtgg gataggtacc attccagagt
     5641 cagtttacgg gctaccgttc catagactag ctcggtcact aagcccttgt ctgctgcaga
     5701 gagctgactc cccttgaggt gtttatttaa ggcgatattt gaatatgctt ggttcacaaa
     5761 aacatcctct agcactgcta gagctaaact tctagccgtt tctactttag tcaccaaatc
     5821 gttctcctac agtcaatgta cgtccaactc cgttgaggaa ggaagcaatg tccatcttag
     5881 gcttaccagc tggctgcact tgtttgaggg atagagcccc ttcagccgtt gcgacaatca
     5941 attctttctt gccgatagag agaatctcac ctggatttcc ctgaccttct actggtaggg
     6001 cttcataaat cttaaagcgg tcgcccttaa ggaaagtatg ggcaacaggc caggggttca
     6061 ttccacgaat ttggttaaag agttgacgat tggttttgtt ccagtccagt ttttcttcct
     6121 ctggctttat atttggagag aaggtaacct gactcgtatc ctgcggttca ggtttgatat
     6181 caccagcaat ataggcaggc agagtgtcca aaagcaaatc acgaccaact agcgccaatt
     6241 tttcaaacaa ggcgccaaca ttgtcctcat ctgtgatcgg aatgctgcga cgagaaatca
     6301 tatctcctgc atccatttcc ttaaccattt ccatgatggt cacaccagct tcctcatccc
     6361 cttgaatcaa ggcataatgg ataggcgcac caccacggtg tctaggaagg agggaggcat
     6421 gaacgttgac agcaaagtcc atgctatcaa ggagtttgct tgggagaaac tgcccaaaag
     6481 cagcagtcac aattccatct gctcctagct tcataagatc ttccatctct ggacttccag
     6541 ataatttttc aggttggtag atagatagtc ctgcttcctt ggcagcctgc ttgactgggg
     6601 tttcttggat aactttttta cgaccaacag cacggtctgg ctgggtcaca acggctagaa
     6661 tttcgtaacg gtcatctgtc aaaagtcctt ttaagactgt tgctgaaaag tcgggggtcc
     6721 ccataaagat tagttttgtc atatcttctc cttcttataa aaattgctgc ggctcatggt
     6781 caatgctgag acggagctca ctattttccc gttcttgagt caaggccagg acctggttga
     6841 gggtcggccc cagctcatct tctaaacggt atttaattaa aatctggtaa tgatagaggt
     6901 tgtgggtacg ggcaatcggt tttggcgttg gccccagaat ggaactggtc tctgacaagc
     6961 ttgaccgcaa aatattcatg acttcatagg cacgtttgac cacctcttct tctttcttgt
     7021 gagaaagggt aataccaatc gtgaaatagt aaggtggata gccgagttgt cgtctgattc
     7081 ccatttcata ggcataaaag ccttcgtaat cttgatcctt ggcaaatcga atagcatagt
     7141 gctgcggatt gtaggactgt atcaagactt gacctgcctt ttcagcccga cctgctcgac
     7201 ctgccacctg agtcaagagc tggaaggttc tctcagaaga acggaaatca ggcagattca
     7261 aggccgtatc cgcatttaga actccgacta gggtaacatt gggaaaatcc aaaccctttg
     7321 caatcatctg agtaccaagt aaaatatccg cttcccctcg cccaaactgg tcaagcaagg
     7381 cttggtgact gcctttcttt cgagtcgtat ccacatccat cctcagaatg cgagcttggg
     7441 gaaagagttc tgctagctca tcataagcct tctgagttcc cgtcccatag taacgaatac
     7501 tgcggctctt acagttagga cagacctgag gaatatcctt cgagaaacca caataatggc
     7561 agttcatagt cttggtatcc atatgcaagg tcagagaaat atcgcagttg ggacaagtat
     7621 ccaccgtccc acactcccga cacatgacaa agctagaata accacggcga ttgagcatga
     7681 gaaccacctg ctctttttta accagacggt cttggatagc ctctagcaaa ggaggcgtaa
     7741 agtttgacgt ctcattttgt ccgatatagt ctcgaaagtc aatcacttga acctcaggga
     7801 ttgtagccaa aggattggca cgttgggtta gacgtaagtg ttgatagacg cctttgccag
     7861 cacgtgcccg gctctctaag ctcggcgttg cagatccaag taccagagtt gcttgattat
     7921 actgagcccg taaaatagct acctctctgg catggtaacg gggattgctg tcctgcttat
     7981 aagccgcttc atgctcttca tcaataatca tgacacccag atttttcaga ggagcaaaga
     8041 tagcagatct ggcaccaaca acaacttggg catcgccacg ctccaccttg cgccattcat
     8101 catacttttc accattggat aatcctgagt gaagaatggc taccttgtcc ccaaaacgtg
     8161 ctataaaacg ctcggtcatc tgaggagtca aggaaatctc aggtaccagc aaaatagctg
     8221 tcttgccctt atccagggca ccttggataa tctgcaagta aacctcggtc ttcccacttc
     8281 ctgtaatccc ttgaagtaga aagggaggtt gagaactgcc aatagaactc acaaccgcat
     8341 cacgcgcctg tctttgttct ggatttaact ccaaaggtct acttgcttca attccttcaa
     8401 aataagcagc cgagcgttga acttcctttt ggactatggt aacagcacct tgatccacaa
     8461 agaagttgac ttgctctcgc gagtaggact ctaacaagct agccaaggaa gcgctctctg
     8521 gatgagacag cagataatct ctcagttcca actttttctt ggcacgtgta gaaatctcaa
     8581 caccttctaa ttgagcatgg tcaacctcat accaagactg ggtcttgacc ttcttttgat
     8641 cgactgcctg atattccaga ccaagcaggc cttttctagt caaacgcatc atttcagctt
     8701 gcttggcaag gtctagtgaa gaaaaggcta gcgaatcttc tgaaccaaac aggcgcactc
     8761 gttcttcctg actcaagcct tccagaggat agagaatctt gtcatagcta gaattcagaa
     8821 accctggaag catggccttg aggatagaga ttttgtagga gaagacagat ttgcgtaact
     8881 cctcagccag ccagagttgt tctggcgtga gaacaggaga aaaatccagc acctctgcaa
     8941 tatcttttaa atcttgctcc atctcttctc catctgattg ggacttcaaa ccaagaacaa
     9001 tcccttgaat caggcgatta cccttaccaa aaggcacatg aacccgcatc ccaacttcca
     9061 gcattccctc aaattcctcc ggaatcctgt aactataggg ctggtccgtc tgcatcaagg
     9121 gcacatctac gataatctta gctagggcca tcttctcacc tcctccttgt cagtacattc
     9181 ttgcaataga aaaaataaga ttgagtcccc ccaaccttaa attttttcac catcttcttt
     9241 ttctttagca atttgctctt tgattttctt ttcttcttct tctttgcggc gtttttcttc
     9301 ttcgatacgg cgacgcactg cttcacgttt tccttctgga tctgggtgaa ttgtaacgtt
     9361 tcctgattcg atttcttcta aagcgcgaag agttgatttt tcagacttga aaccttgagt
     9421 tgctggggca cctgcttcca attcgtgggc acgttttgct tccaagatta cgagtgaata
     9481 ttttgaagga accttgtcga gcaaggtatc aatagagggt tttaacatca tttgcttgta
     9541 cctattttct aaattttatc gggtagttgg agattttggt aacatctcct gatagtgacc
     9601 aatgacacga tccacacaga agtgttctgc ttcaatcaca catttgacac gttcagcagc
     9661 taggggtacc tgatcgttga caatcgcata atcatactca cgcatgaggg caatttcttc
     9721 cttggccttt tcgattcgtt gggcaatcac ttctgcacta tctgttccac gacctaccaa
     9781 gcgatcttgc aattcatcca aatctggtgg tgtcaggaag ataaagacag catctggaac
     9841 ctttttcttg acctgaagag caccctgaac ttcaatttca aggaaaacat cgattccctt
     9901 gtccaaggtt tcattgacat aggtcagagg agttccatag tagttaccga catattctgc
     9961 gtattccaac atctgtcctt gacgaatcag ctcttcaaat tcttcacgag tacggaagaa
    10021 atagtcaaca ccgtccactt ctccaggacg ttgtgcgcgt gtcgtcatcg atacagaata
    10081 ttgaaattgg ttttcagaac tctcaaaaat ctctcttcta accgttcctt ttccaacccc
    10141 tgaaggacca gaaaaaacga ttagtaagcc tcggtctgcc attgtgtctc cttttagtca
    10201 atctgtgaaa taacatttct ctagaataat ggcaaaaagc cagattatcc tttacagtct
    10261 ttctatctag tgtaacaaaa aagcagtaat ttttcaactg ctctttctta tttatttagc
    10321 ataatctact gcacgaagct cgcgaatcac ggttaccttg atatttcctg gataatcgag
    10381 attgttttca attttcttac gaactttgtg agccaagatt gtgactttgt cgtccttgat
    10441 ttttcctgga ttgaccatga tacgaatttc acgtcctgct tgaagggcaa agctagtttg
    10501 cactccttca aagccgttag caatttcttc caaatcatgg agacgcttga tgtagctttc
    10561 aagagactca ctacgagcac ctggacgggc tgcgctcaag gcatctgctg cagcgacgat
    10621 aactgctatc acgctctcag cttcaacatc tccgtggtga ctagcaatcg tattcaccac
    10681 aactgggggt tccttgtact tacgggccaa ttccataccg atttcaacgt ggctaccttc
    10741 aacctcatgg tcaatggctt tcccgatatc gtgaaggaat ccagcacgac gggcaagagc
    10801 cgcattttca ccaagttcgc tcgccatgat accagccaac ttagcaacct caatcgaatg
    10861 gcgcaaaaca ttttgtccat atgaagtacg gaactgcaaa cgtcccataa tcttcatcaa
    10921 gtctggatga aggtttggcg caccaatttc ataggcagca gcctcaccgt attcacgaat
    10981 cttattgtca atctcttgac ggtttttctc aaccaactct tcgatacgag ctggatgtat
    11041 acgaccatct ttgagcaaca tttccatagt catacgggca atctcacgac gaatcggatc
    11101 aaatcctgac aaggtcacca cttctggtgt atcgtcgata atcacatcga cccctgtcaa
    11161 actttcaaag gtacgaatgt tacgaccttc acgaccaata atgcgtccct tcatagtatc
    11221 gtctggcaga tgaactgttg agtttgttga ctccgctaca tattcaccag cgatacgttg
    11281 catagcttga accaagatgt ccttggccat tttgtcagaa cgttccttga cctcttgctc
    11341 agcttcgcga atgcgactgg caatctccct ggtcaagttt tcctctgtct gagccaagat
    11401 aatatctcgt gcttctgcct gagacagcgc accaatacgc tctagttctg cttctttttg
    11461 tctttcgact tcctctaatt gctcttcacg cgcatcaagg tttttcgctc tatcagaaat
    11521 actttgttct ttttgttcaa gtgtttgttc tttactcgtc aaattgtcgt ccttacggtc
    11581 aaggctagta gctctctctg tcaaacgact ttcgatttgt ttgagttctt gacgttctga
    11641 tttgaattca gcgtccactt cttcacggta ttttctggct tcttctttgg cctccaatag
    11701 tgcttctttt ttaagagact tgctttcacg tttggcttca ttaacaagta aatccgcttc
    11761 acgctcagct tgtccacgta aattagttgc ttcttgttca gcatttaaaa gcatcaactc
    11821 tgcagcttcc tgagatgatt tcatcttagc tgagatgctg acatatccaa tgactaaacc
    11881 aatgatgacg gcaaaaacag caatcgcaag cgacatgatt tccatgtttt tacctcattt
    11941 tattgttatt ccgaatgaca tacattcttt tacattctac cataaaaaag tgattttcac
    12001 aaacctaaaa tagaatatgt tttgaggaat ttggaacaca tttaccaaaa taaacttgtt
    12061 gtttagaaat agtagtttag tagagacttg agaaaaagcc tacctttcaa tagacttagt
    12121 aatgatcttt aaaggacaag aaagccacgc tatctccatc catcatataa atcaagcgat
    12181 tttctgcatc aatacgccgt gaccaggctc cttggtaatc atatttgagt ggttctggtt
    12241 tacctattcc tgtaaaggga tcacgttgaa tatccttgat tagtttattg attcttttta
    12301 acgttttctt atcctgattt tgccagtagc aataatctgc ccaggcatct tctgtaaact
    12361 tgagcagcat ttcttactcc tcaataacat ggacctgagt acttccagca cgaacttgag
    12421 ccattcctcg caaaacctta tcagaaagtt ccttattttg agcaattctc agggtttctt
    12481 ggatactatc ccactcactc tttgaaagga ctacaatgtc ctcatctgga tttttattga
    12541 ccaccgtcaa aggctcaaat tcatcattta ccttcttcat gtagtccttt aaatgatttc
    12601 ggaatgttga gtaaaggact gcttccataa ccatacctcg ttttagctct tttccactat
    12661 tatacacgaa aagaaagaaa ttgtcaggaa cttgtacaag attttctttt ctatctatt
//
LOCUS       DBEJAU010000054        11573 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC323 isolate 683620
            SAMN38261939-rid24807223.denovo.054, whole genome shotgun sequence.
ACCESSION   DBEJAU010000054 DBEJAU010000000
VERSION     DBEJAU010000054.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261939
            Sequence Read Archive: SRR26833919
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 11573)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11573)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576303.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576303.1
            Genome Coverage       :: 154x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/19/2025 01:05:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,121
            CDSs (total)                      :: 2,078
            Genes (coding)                    :: 1,943
            CDSs (with protein)               :: 1,943
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 36
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 72 of 135
            Pseudo Genes (incomplete)         :: 63 of 135
            Pseudo Genes (internal stop)      :: 51 of 135
            Pseudo Genes (multiple problems)  :: 46 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11573
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261939-rid24807223.denovo.054"
                     /strain="GPSC323"
                     /isolate="683620"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            87..1409
                     /locus_tag="ACL29Z_001759"
     CDS             87..1409
                     /locus_tag="ACL29Z_001759"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001059752.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0016773 - phosphotransferase activity,
                     alcohol group as acceptor [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HGR0070024.1"
                     /translation="MNNILAFLETKVAPFGEKVGNQRHLKAIREGFMMAMPLILVGSL
                     FLILISWPQEAFTNWLNSVGLLSILTTMNQSTVAIISLVACFGIAYRLSEGYGTDGPS
                     AGIIALSSFVLMAPRFSSMVYDKNGEQVKQLFGGAIPFSSLNASSLFMAITIGLVTAE
                     IYRMFIQRGITIKMPSGVPDVVSKSFSALLPGFTTFVLWALVLKGLEAAGVAGGLNGL
                     LGAIVGTPLKLIAGTLPGMILCVIVNSFFWFCGVNGGQVLNAFVDPVWLQFTTENQEA
                     VAAGQTLQHIITLPFKDLFVFIGGGGATIGLAICLFLFSKSRANKTLGKLAIIPSIFN
                     INTAILFTFPTVLNPIMLIPFIATPTINALITYVSMAVGLVPYTTGVILPWTMPPIIG
                     GFLATGASWRGALLQVVLILVSVAIYYPFFKIADKRNLEKEKATVGGK"
     gene            1411..3297
                     /locus_tag="ACL29Z_001760"
     CDS             1411..3297
                     /locus_tag="ACL29Z_001760"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000236922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4838 domain-containing protein"
                     /protein_id="HGR0070025.1"
                     /translation="MVIRVFDQQKNTYSSFALEELSYYMNRVFKTNIELVEEKEADIF
                     VGLVNKEDRKDHVLISLDKGKGRIESNTIVGLLIGIYRMFHEFGVVYTRPGRRHDFVP
                     ELRFEDFLDKQLSIDETASYYHRGVCIEGADSFENILDFIDWLPKIGMNSFFIQFENP
                     YSFLKRWYEHEFNPYLNKEKFSNELVQELSDRLDKELQKRGLIHHRVGHGWTAEVLGY
                     SSKFGWESGLSISEEKKPYVAEINGKRELFNTAPILTSLDFSNPDVADKMVEIIKDYA
                     KKRPDVNYLHVWLSDARNNICECENCRQELVSDQYIRILNQLDRALTSEGLDTKICFL
                     LYHELLWAPQKEKLDNPERFTMMFAPITRTFEMSYADVDFDNSIPTPKPYLRNKIILP
                     NSLEENLSYLFEWQKTFKGDSFVYDYPLGRAHYGDLGYMKISQTIYRDVSYLSNLHLN
                     GYISCQELRAGFPHNFPNYVMGEMLWKKTRSYEELIEEYFSALYGSNWQSVVEYLEKL
                     SSYSSCDYFNAIGSRQNDVLANHYYIAYNLADNFLPIIEENISKLLNSQKDEWKQLSY
                     HREYVVKMAKALYLQATGKTRQAQDEWRNVLNYIRGHELLFQSNLDVYRVIEVAKNYA
                     GFHL"
     gene            3465..3809
                     /locus_tag="ACL29Z_001761"
     CDS             3465..3809
                     /locus_tag="ACL29Z_001761"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000836781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HGR0070026.1"
                     /translation="MKSKEEINMLGFTIVAYAGDARSDLMDALAFARDGYFEQARELV
                     ESANDSIVSAHREQTNLLAEEASGDNFEVSFIMIHGQDTLMTTMLLYDQVKFFIDEYE
                     RIRKIEEHIGLQ"
     gene            3819..5231
                     /gene="lacG"
                     /locus_tag="ACL29Z_001762"
     CDS             3819..5231
                     /gene="lacG"
                     /locus_tag="ACL29Z_001762"
                     /EC_number="3.2.1.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000429433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0033920 - 6-phospho-beta-galactosidase
                     activity [Evidence IEA];
                     GO_process: GO:0019512 - lactose catabolic process via
                     tagatose-6-phosphate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-galactosidase"
                     /protein_id="HGR0070027.1"
                     /translation="MENLQVKALPKEFLLGAATAAYQVEGATRVDGKGTNMWDVYLQE
                     NSPFLPDPASDFYYRYEEDIALAAEHGLQALRLSISWVRIFPDIDGEPNILAVRYYHR
                     VFQSCLKHNVIPFVSLHHFDSPQKMLETGDWLNRENIDRFIRYARFCFQEFTEVKHWF
                     TINELMSLAAGQYIGGQFPPNHHFQLSEAIQANHNMLLAHALAVLEFHQLGIEGKIGC
                     IHALKPGYPIDGQKENILAAKRYDVYNNKFLLDGTFLGYYSDDTLFHLNQILEANNSS
                     FIIEDGDLEIMKRAAPLNTMFGMNYYRSEFIREYKGENRQEFNSTGIKGQSSFKLNAL
                     GEFVKKPGIPTTDWDWNIYPQGLFDMLLRIKEEYPQHPVIYLTENGTALKEVKPEGEN
                     DIIDDSKRIRYIEQHLHKVLEARDRGVNIQGYFIWSLQDQFSWANGYNKRYGLFFVDY
                     ETQKRYIKKSALWVKGLKRN"
     gene            5301..6980
                     /locus_tag="ACL29Z_001763"
                     /pseudo
     CDS             5301..6980
                     /locus_tag="ACL29Z_001763"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000359733.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose transporter subunit IIBC"
     gene            complement(7105..8544)
                     /locus_tag="ACL29Z_001764"
     CDS             complement(7105..8544)
                     /locus_tag="ACL29Z_001764"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519662.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015079 - potassium ion transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TrkH family potassium uptake protein"
                     /protein_id="HGR0070028.1"
                     /translation="MNKSMIRYLLSKLLLIEAVLLLVPVAIAVYYRESSQVFTALFST
                     IGILVLLGGSGSLQKPKNQRIYAKEGVLIVALCWILWSFFGGLPFVFSGQIPSLIDAF
                     FEISSGFTTTGASILNDVSVLSRSLLFWRSFTHLIGGMGVLVFALAIMDNAKNSHLEV
                     MKAEVPGPVFGKVVSKLKNTAQILYLLYLALFSLFVIIYYLAGMPLYDSFVIAMGTAG
                     TGGFTVYNDGIAHYGSSLITYLVSIGVLVFGVNFNLYYYLMLRRIKAFFGDEELRAYL
                     VIVLVSTGLISLNTLYLYPGFSKSFEMTFFQVSNIITTTGFGYGDITNWPLFSQFILL
                     FLMAIGGSAGSTAGGLKIIRGLILSKIAKNQILSILSPHRVLTLHVNKTVIDKDTQHK
                     ILKYFVIYAMILLALIFIVSLDSNDFLVVTSAVFSCFNNIGPILGTTSSFSIFSPISK
                     ILLSFAMIAGRLEIYPILLLFMKRTWSKR"
     gene            complement(8548..9897)
                     /gene="trkA"
                     /locus_tag="ACL29Z_001765"
     CDS             complement(8548..9897)
                     /gene="trkA"
                     /locus_tag="ACL29Z_001765"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000691677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Trk system potassium transporter TrkA"
                     /protein_id="HGR0070029.1"
                     /translation="MKIILVGGGKVGFALCRSLVAEKHDVLLIEQDEAVLNHIVSRFD
                     IIGILGNGADFAILEQASVQDCDIFIALTEHDEVNMIAAVLAKKMGAKETIVRVRNPE
                     YSNSYFKEKNILGFSLIVNPELLAARAIANIIDFPNALSVERFAGGRVSLMEFVVKST
                     SGLCQMPISDFRKKFGNVIVCAIERDHQIIIPSGDMTVQDKDRIFVTGNRVDMILFHN
                     YFKSRAVKSLLIVGAGRIAYYLLGILKDSRIDTKVIEINPEIASFFSEKFPNLYIVQG
                     DGTAKDILLEESAQHYDAVATLTGVDEENLITSMFLDRVGVQKNITKVNRTSLLEIIN
                     APDFSSIITPKSIAVDTIMHFIRGRVNAQYSDLQAMHHLANGQIETLQFHIKEANKMT
                     AKPLSQLKLKKGVLIAAIIRKGKTIFPTGEDMLEVGDKLLVTTLLPNITKIYDLIAR"
     gene            10086..10934
                     /locus_tag="ACL29Z_001766"
     CDS             10086..10934
                     /locus_tag="ACL29Z_001766"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S-adenosyl-l-methionine hydroxide
                     adenosyltransferase family protein"
                     /protein_id="HGR0070030.1"
                     /translation="MNNNLLVLQSDFGLVDGAVSAMIGVALEESPTLKIHHLTHDITP
                     YNIFEGSYRLFQTVDYWPEGTTFVSVVDPGVGSKRKSVVAKTAKNQYIVTPDNGTLSF
                     IKKHVGIVAIREISEVANRRQNTEHSYTFHGRDVYAYTGAKLASGHITFEEVGPELSV
                     DQIVELPVVATIIEDHLVKGAIDILDVRFGSLWTSITREEFYKLEPEFGDRFEVTIYH
                     ADMLVYQNQVVYGKSFADVRIGQPILYINSLYRLGLAINQGSFAKAYNVGVGSSWTIE
                     IKKIEG"
     gene            10949..11497
                     /locus_tag="ACL29Z_001767"
     CDS             10949..11497
                     /locus_tag="ACL29Z_001767"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000403170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ECF-type riboflavin transporter
                     substrate-binding protein"
                     /protein_id="HGR0070031.1"
                     /translation="MEIKFTIKQVVAVGIGAALFVVIGMINIPTPVPNTSIQLQYAVQ
                     ALLSIIFGPIIGLLVGLIGHAIKDSLVGYGLWWTWIIASGLFGLVVGLFRKYVRVINS
                     VFDWKDILIFNLIQLLANALVWGVLAPLGDVVIYQEAAEKVFAQGIVAGIANGVSVAI
                     AGTLLLLAYAGTQTRTGSLKKD"
BASE COUNT         3513 a         1900 c         2512 g         3648 t
ORIGIN      
        1 ttgtaaaaac aacaaaaaat atattgacaa cgctttctgt tagtggtata tttaatttat
       61 aaaaaataaa aaaaggagtt ccggtgatga acaatatttt agcgttttta gaaacaaaag
      121 tcgctccgtt tggtgaaaaa gttggcaacc aacggcattt gaaagctatt cgtgaaggat
      181 ttatgatggc aatgcctttg attttagtcg gctctttatt tcttattcta atcagttggc
      241 ctcaagaggc ttttacaaat tggctgaata gtgttggatt gctaagtatc ttgacaacta
      301 tgaatcagtc aacagtagcg attatctcct tggtcgcttg tttcggtatt gcctacaggt
      361 tgtcggaagg atatggtaca gatggtccgt cggcagggat catagcctta tccagttttg
      421 tattgatggc acctcgtttt tcgagtatgg tttatgataa aaatggggag caggtcaagc
      481 agttatttgg cggcgcaata ccattttcta gcctgaatgc atcttctttg tttatggcga
      541 ttactattgg attggttaca gcagagattt atcgtatgtt tatccagcgc ggaattacga
      601 taaaaatgcc aagtggtgtc ccagatgtgg taagtaaatc attttcagct cttttacctg
      661 gctttactac ttttgttttg tgggctctgg tcttaaaagg tcttgaagcg gcaggagttg
      721 caggaggtct caacggactc ctaggtgcaa ttgttggaac accgcttaag ttaattgcag
      781 gaacgcttcc aggtatgatt ctatgtgtta ttgtaaactc attcttttgg ttctgtggag
      841 ttaatggggg acaagtttta aatgcttttg tagacccagt ttggttacaa tttactacag
      901 aaaaccaaga agctgtggct gcaggacaaa cactccaaca cattattaca ttaccgttta
      961 aagatttatt tgtatttatt ggtggcggtg gagcgactat tggtcttgcg atttgtctct
     1021 tcctatttag taagagtcgt gcgaataaaa cattaggtaa gctagctatt ataccgtcta
     1081 tttttaatat caatacagct attctattta cgtttccaac agttttaaat ccgattatgc
     1141 tgattccgtt tattgctact cctacaatca atgccttgat tacctatgta tcaatggctg
     1201 taggattagt accctataca acaggtgtaa tccttccgtg gacaatgcca ccgatcatag
     1261 gaggcttcct tgcgacagga gctagttggc gaggagctct attacaagtt gttttgattt
     1321 tggtttctgt agcaatttat tatccatttt tcaaaattgc agataaacgc aatcttgaaa
     1381 aagaaaaagc tactgttgga gggaaataag atggttatca gagtatttga tcaacagaaa
     1441 aatacttatt ctagctttgc cttagaggaa ttaagttact atatgaatcg ggtctttaag
     1501 actaacatag agcttgtcga ggagaaggaa gcggatattt ttgtaggatt agtcaataaa
     1561 gaggacagaa aagaccatgt tcttatctca ttagacaagg gtaaggggag aattgagtct
     1621 aatacaattg taggtttact tattggaatt taccgaatgt ttcatgaatt tggggttgtg
     1681 tatactagac cagggcgcag acatgacttt gttccagagt tacgatttga agatttttta
     1741 gataaacagc tatctataga tgaaacagcc agttactatc ataggggagt atgtatagag
     1801 ggagcggatt catttgaaaa tatactagat ttcattgatt ggctacctaa gattgggatg
     1861 aacagttttt tcatccagtt tgaaaatcct tactcttttt tgaaacgttg gtatgaacat
     1921 gagtttaatc catacctaaa taaagaaaaa ttctcaaatg aattagtaca agaattgagt
     1981 gataggttgg ataaagaatt gcaaaaaaga ggtcttattc atcatcgtgt tggtcatgga
     2041 tggacagctg aggttttagg ttactcttca aaatttggct gggaatcagg tcttagtatt
     2101 tcagaggaga agaaaccgta tgtcgctgaa ataaacggga aacgagaatt atttaatacg
     2161 gctccgattt taaccagtct ggatttttca aatccagatg tggcggataa gatggtagaa
     2221 attatcaagg attatgccaa gaaaagacct gatgttaact acttacatgt atggttgtcg
     2281 gatgctcgta ataatatttg tgaatgcgaa aactgtagac aagaattggt ttcggatcag
     2341 tatattcgta ttctcaatca attggatagg gctttaacga gtgagggatt agatacaaag
     2401 atttgttttc tgctttacca tgagttgcta tgggcgcctc agaaagaaaa attagataat
     2461 cctgaacgct ttaccatgat gtttgcaccg attacaagaa catttgaaat gagttatgca
     2521 gatgtagatt ttgacaattc catacctacg cctaaacctt atctgcgtaa taaaattata
     2581 cttccgaatt ctcttgagga aaatttatct tatctttttg agtggcaaaa aacatttaaa
     2641 ggagatagtt tcgtatatga ctatccttta gggcgtgctc attatggcga tttaggctat
     2701 atgaaaatta gtcaaaccat ttacagagat gtatcttatc tttctaacct acatttgaac
     2761 ggttacattt cgtgtcaaga attacgtgcc ggattccctc ataattttcc taattatgtt
     2821 atgggggaaa tgctctggaa gaagacaaga agttatgaag aattgattga agaatacttt
     2881 tctgctttgt atgggtcaaa ttggcagtct gttgttgaat atttagaaaa attatccagt
     2941 tattcctcat gtgattattt taatgcaatt ggcagtcgtc aaaatgatgt tttagcgaat
     3001 cattattata tagcttacaa tctagctgat aattttttgc caattattga ggaaaatatt
     3061 tctaagttat taaatagtca aaaggatgaa tggaaacagc tcagttatca tcgtgaatat
     3121 gttgttaaga tggcgaaggc tttatatctt caagcaaccg gaaaaacaag gcaagctcaa
     3181 gatgaatgga gaaatgtgtt gaattatatc cgtgggcacg aactgctatt ccaatctaat
     3241 ttggatgttt atcgtgtaat tgaagtagca aaaaattacg ctggtttcca cttataaatc
     3301 ataagtatag aaaatgaacc aaggtattca gagaagattg atcctaaata ttatgaaatt
     3361 taaggatttt taagatattt agggtcgact ttctatttat atcgtagcga agtcatttta
     3421 ataatgatgt gtaaaagatg gatcaagatt gaggaggaag aaagatgaaa tcaaaagaag
     3481 aaataaatat gcttggtttt acaattgtcg cttacgcagg agatgcaagg tcagatttga
     3541 tggatgcttt ggcgtttgcg agagatggat attttgaaca ggcaagagaa ttggttgagt
     3601 ctgcaaacga ctcaatagtg tctgcccatc gagaacagac taatttatta gcggaggagg
     3661 catctggaga taattttgaa gtgagtttta tcatgattca tggtcaagat actttgatga
     3721 caacgatgct attgtatgat caggtcaagt tttttattga tgaatatgaa cgaattcgaa
     3781 agattgaaga acatattggt ttgcaatgag gattagtcat ggaaaattta caggttaaag
     3841 ccttaccgaa ggagttttta ttaggagctg ctaccgctgc ttatcaagta gagggtgcaa
     3901 ctagggtaga tggcaaagga acaaatatgt gggatgttta tttgcaagaa aacagtccgt
     3961 tcttaccaga tccagctagt gatttttatt atcgttacga agaggatata gctttggcgg
     4021 cagaacatgg tttgcaggct ttgcgtttat ctatttcttg ggttcgtata tttcctgata
     4081 tagatgggga gcctaatata ttagctgttc gttattacca tagagtcttt cagtcttgct
     4141 taaaacataa tgtgattccg tttgtttctt tacatcattt tgattcgcct cagaaaatgt
     4201 tagaaacagg ggattggttg aatagagaga atattgatcg tttcatacga tatgctcgct
     4261 tttgtttcca agaatttaca gaagtcaagc attggtttac aatcaatgaa ctgatgtctc
     4321 ttgctgcagg tcaatatata ggaggtcagt ttcctccaaa tcatcatttt caattatctg
     4381 aagcaattca agcgaatcat aatatgttgt tggcgcatgc tcttgcagtc ctcgaatttc
     4441 atcaattagg gattgaggga aagataggtt gtattcatgc tttaaagcca ggctatccta
     4501 ttgatgggca aaaagaaaat attttagcag ctaaacggta tgatgtttat aataataaat
     4561 ttctattaga tggaactttt ttgggctact acagtgatga cacgcttttt cacttgaatc
     4621 aaatattgga agctaataat tctagcttta ttattgaaga tggtgattta gaaattatga
     4681 aaagagctgc acctcttaat acgatgtttg ggatgaatta ttatcgttca gaatttattc
     4741 gtgaatacaa aggtgaaaat agacaagaat ttaattcaac aggaataaaa ggacagtctt
     4801 cttttaaatt aaatgctcta ggtgaatttg taaaaaagcc tggtattccg acaacagatt
     4861 gggattggaa tatttatcct caagggttat ttgatatgtt gcttcgtatc aaagaagaat
     4921 atcctcaaca tccggtcatt tatttaactg aaaatggtac agcccttaaa gaggttaagc
     4981 cagagggcga gaatgatatt attgatgaca gtaaaagaat ccgttatatt gagcaacatt
     5041 tacacaaagt tttagaggct cgagataggg gagtcaatat tcaaggctat tttatatggt
     5101 ctttgcaaga tcaattttct tgggcgaatg gctacaataa gcgatatggt cttttctttg
     5161 ttgattatga aacacagaag agatatatta agaaaagtgc tctttgggta aaaggattaa
     5221 aacggaatta aggttagcga tttgactgat gtttaatata ttttaactat gagcttaaat
     5281 tttttacagg aggagttttt atggataagt tagtcgctgc cattgaaaag caacaaggga
     5341 aatttgaaaa aatttctact aataattata tgatggctat taaagatgga tttattgcta
     5401 ctatgccttt aattatgttt tcaagctttt tgatgattat tattatgatt cctaaaaatt
     5461 tcggagtaga gttaccgagt ccagctattg cctggatgag gaaagtgtat atgctaacca
     5521 tgggagtttt gggtgttatt gtttcaggga cagttgcaaa gtcattggct ggaaatgtta
     5581 atagaaaaat gcctcctgga aaggtaataa atgatacttc tgcaatgttg gcggccatat
     5641 gtggctatct tgtattaact gtaacgcttg tagttgatga gaaaacggga tctacaagtt
     5701 tgtcgacaaa ctatttagga tctcaaggat tgataacttc gtttgtcagt gcctttatta
     5761 ctgtaaatgt ttaccgattc tgtattaagc gagacattac tattcattta cctaaggaag
     5821 ttcctggggc tatatcacaa gcttttagag atactttccc tttttctttt gttttactta
     5881 ttagtggttt gttagatatt gtatctcggt ttagtttaga tgttcctttt gcccaagtat
     5941 ttcaacaact attgactcct atttttaagg gggcagaatc atatcctgct atgatgttga
     6001 tttggtttat gtgtgctttg ctttggtttg ttggaattca tggaccatct attgtcttac
     6061 ctgctgttac agctttgcaa ctgagcaata tggaagagaa tgctcaactt cttgcaaatg
     6121 ggcagttccc ttatcattct ttaacaccta atttcgggaa ttatatcgct gctattggag
     6181 gaacgggggc tacctttgtt gtaccattta ttttgatttt ctttatgcgg tctaaacaat
     6241 taaaatcggt aggtaaagct acaattactc ctgttttatt tgcggtaaat gaacctcttc
     6301 tatttggtat gcctgttatt ttgaatccct atctttttgt cccttttttg atgactccac
     6361 cagtgaatgt atttctagga aaggtattta ttgatttctt tggaatgaat ggattttata
     6421 tccagttacc ttggaccttt cctggtccct tgggattgtt aattggaacg aattttcaac
     6481 ttatctcctt tgtattttta tctttgattt tagttgtcga catattgatt tatttgccat
     6541 tctgtagagc gtatgataga cagttactgg tgaaagaaga tattgcaagc tcaaatgata
     6601 ttattttaga ggaggataca agtgaaataa tgcctggtga gatagatgta ataaaaagta
     6661 aggagttgaa agtactggtt ctttgtgcag ggtctggaac aagtgcgtaa ttagccaatg
     6721 caattaacga gggcgctcaa ttagcagaag ttagagtgat tgcgaattca ggagcgtacg
     6781 gagctcatta tgatattatg ggtgtttatg atttaattat tctggctcca caagttcgga
     6841 gttattatag agagatgaag gtggatgcag aaagattagg tattcagata gttgctacca
     6901 gaggaatgga atatattcat ttaacaaaga atccaagtaa agccttacaa tttgtattgg
     6961 agcattacca agctgtgtag taagtttttc catcttttat ttgagtaaga actttgctta
     7021 cagacaggct tggatttaaa aacgttcccc ctttttaata taaaaatccc tctttcacaa
     7081 ttgtaaaaag agggattttg tattttatct cttagaccaa gttcttttca taaagagaag
     7141 gaggattggg taaatctcca agcgccctgc aatcattgca aaggatagga gaatttttga
     7201 gatgggacta aagattgaga aactagaagt ggttcctaga ataggcccga tattattgaa
     7261 acagctaaag acagcgctgg tcacgaccag aaaatcattg ctatctaggc tgacaataaa
     7321 gataagcgct agcaaaatca tagcatagat gacaaagtac ttgagaatct tatgctgggt
     7381 atctttgtca atcaccgttt tattaacatg gagggtcaaa acacggtggg gcgataggat
     7441 tgacaaaatt tggtttttgg caatttttga aaggatgagg cctcgaataa tcttgagtcc
     7501 acctgcagtt gatccagcag agccaccgat tgccatgagg aaaaggagga taaactggga
     7561 gaagaggggc cagttggtaa tatctccata tccaaaacca gttgttgtaa tgatgttgga
     7621 aacctggaag aaggtcattt caaagctctt tgaaaaccct gggtagaggt agagggtgtt
     7681 gaggctaatc aagcctgtag aaaccagtac aatgaccaag taagccctaa gctcttcatc
     7741 tccaaagaag gccttgatgc gacggagcat gaggtagtag tagaggttga aatttactcc
     7801 aaaaaccaga actccgatac tgaccagata ggtaatcagt gagctgccat agtgggcaat
     7861 tccgtcgtta tagacggtaa agcctccagt tcccgctgtc cccatagcaa taacaaaact
     7921 atcgtagaga ggcataccgg ctagataata gatgatgaca aagagggaga agagagctag
     7981 ataaaggaga tagagaatct gggcagtgtt ttttagtttg gatacaacct tgccaaaaac
     8041 aggacctgga acctcagcct tcatcacctc taggtggcta tttttggcat tgtccataat
     8101 agcaagtgca aaaacaagca ctcccatccc tccaatcaag tgggtaaaac ttcgccagaa
     8161 gaggagggaa cggctgagaa ccgaaacgtc gttcaaaata cttgctccag tagttgtaaa
     8221 tccagaacta atttcaaaaa aggcatcaat aaggctgggg atttgcccag aaaagacaaa
     8281 ggggagacca ccaaagaaag accaaaggat ccaacagagg gcaacgatca agactccctc
     8341 cttggcataa atccgttgat tttttggctt ctgtaaactc cctgaaccgc ctaacaatac
     8401 gagaatccct atggtcgaaa agagggctgt aaagacttgg ctcgattcac ggtaatagac
     8461 agcaatcgca acaggaacca aaagaagaac agcttcaatc aaaagtaatt ttgaaaggag
     8521 gtaacgaatc atacttttat tcatttctta cctcgcgatc aagtcataaa tcttggtgat
     8581 gtttggcaac aaggttgtta ctaggagctt gtctccaact tccaacatat cctccccagt
     8641 tgggaaaata gtcttgccct ttcgaataat ggctgcaata agaacccctt ttttcaattt
     8701 cagttgagaa agaggtttgg cagtcatttt attggcttcc ttgatatgga attgcagggt
     8761 ttcgatttgg ccattggcta gatggtgcat agcttgaagg tctgaatact gggcattaac
     8821 tcgaccacga ataaagtgca taatcgtatc tacagcgatg cttttaggtg tgatgatact
     8881 tgaaaaatca ggcgcattga taatctcgag gagactggta cgattgacct tagtaatatt
     8941 tttctgtaca cctaccctgt caaggaacat agatgtaatc agattttcct catcgactcc
     9001 tgttagagtc gcaacggcat catagtgttg agcactttct tccagcagga tatcttttgc
     9061 ggttccatct ccttgaacga tgtagagatt tgggaatttc tcgctaaaga agctggcgat
     9121 ttcaggattg atttcaatga cttttgtatc gatacgacta tctttgagaa taccaagtag
     9181 ataataggca attctacctg ccccaacgat gagaaggctc ttcacggcgc gtgatttaaa
     9241 ataattatgg aagagtatca tatcgacacg gttaccagtg acaaagattc tatctttatc
     9301 ctgtacagtc atgtcaccgc ttggaatgat aatttgatga tccctctcta tcgcacagac
     9361 aatgacatta ccaaattttt tacgaaaatc agaaatgggc atttggcaaa gaccgctggt
     9421 ggacttgacg acaaattcca tgaggctaac gcgtccacca gcaaagcgtt cgacagacag
     9481 ggcgttgggg aagtcaatga tattcgcgat agcgcgggca gccaagagct caggattaac
     9541 gataagagaa aaaccgagaa tattcttttc cttgaaataa gagttagaat attcagggtt
     9601 ccgcacccga acgatagttt ctttagctcc cattttcttg gctagaactg ctgcaatcat
     9661 gttgacttca tcgtgctcag tcagggcgat aaagatatca caatcttgga cgctggcttg
     9721 ctcaagaatg gcaaaatcgg ccccattacc aaggatacca atgatatcaa agcgactgac
     9781 aatatgattg agaacagctt cgtcttgctc aatcagcaaa acatcatgct tttctgcaac
     9841 caaggagcga cagagggcaa aaccaacttt tccccctccg acaaggataa ttttcataat
     9901 aaaacctact ttttcatgat gtaactatca tacccttttt caagaaaaaa tgcacctact
     9961 agctaataac aagaactttt agtaggaaat ttgctataag gtaaaactat accctaacca
    10021 attgaaatag ctattagcga ctttctctga aatatggtat gataaaggat atacaaggag
    10081 ataaaatgaa taataattta ctggtattac aatcagactt tggtctggtt gatggtgcgg
    10141 tatcggctat gattggagtg gctttagaag agtctccaac cttaaaaatc catcacttga
    10201 cgcacgatat cacgccttat aatatttttg aggggagcta tcgtctcttt cagacggtgg
    10261 attactggcc tgagggaacg acgtttgtat cggttgtcga tccaggtgtc ggttcgaaac
    10321 gtaagagtgt agttgccaag actgcaaaaa atcaatacat tgtcacgcca gataatggga
    10381 cgctttcctt tatcaagaaa cacgttggca ttgtagccat tcgtgagatt tctgaggtgg
    10441 ccaataggcg tcaaaacaca gagcattctt ataccttcca cggtcgtgat gtctatgcct
    10501 atactggtgc taaactggcc agtggtcaca ttacttttga ggaagtaggg ccagagctca
    10561 gtgtggacca gattgtagag cttccagtcg tagcgaccat catagaagat catctggtga
    10621 agggagccat tgatattctg gatgtgcgtt tcggttcgct ttggacctct atcacacggg
    10681 aagaatttta caagctggaa ccagaatttg gtgatcgttt tgaagtgacc atctatcatg
    10741 ctgatatgct ggtctatcaa aatcaggttg tctatggcaa atcatttgca gatgtgagaa
    10801 ttgggcaacc catcctttac atcaactctc tctatcgttt aggtttggct atcaaccaag
    10861 gttcctttgc caaggcctat aatgtaggtg tcggttcatc ttggaccatt gaaataaaga
    10921 aaatagaagg ataaaatagg agaatagtat ggaaatcaaa tttacaatta aacaagttgt
    10981 tgctgtcgga attggcgctg ccctctttgt cgtcatcggg atgatcaaca ttccaacccc
    11041 tgttccaaat acaagcatcc agcttcagta tgcggtacaa gcgctacttt ctattatttt
    11101 tggaccgatt atcggtttgc ttgtcgggtt gattggtcat gcaatcaagg actctcttgt
    11161 tggttatggt ctatggtgga cttggattat cgctagcgga ctctttggtt tagttgtggg
    11221 actttttaga aagtacgttc gcgtgatcaa tagtgttttt gactggaaag atattcttat
    11281 ttttaatctc attcaactac ttgcaaatgc ccttgtttgg ggtgtcttgg caccacttgg
    11341 agatgttgtg atttatcaag aagcggcaga aaaagtattt gcacaaggga ttgttgcggg
    11401 aattgccaat ggtgtatctg tagctattgc aggaactctt ctcttacttg cctatgcagg
    11461 aacccaaact cgtacaggaa gtttgaaaaa ggactaatac tcaatgaaaa tcaaagagca
    11521 aactaggaag ttagccgcag gttgctcaaa acagtgtttt gagattgtgg ata
//
LOCUS       DBEJAU010000055        10788 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC323 isolate 683620
            SAMN38261939-rid24807223.denovo.055, whole genome shotgun sequence.
ACCESSION   DBEJAU010000055 DBEJAU010000000
VERSION     DBEJAU010000055.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261939
            Sequence Read Archive: SRR26833919
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 10788)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10788)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576303.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576303.1
            Genome Coverage       :: 154x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/19/2025 01:05:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,121
            CDSs (total)                      :: 2,078
            Genes (coding)                    :: 1,943
            CDSs (with protein)               :: 1,943
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 36
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 72 of 135
            Pseudo Genes (incomplete)         :: 63 of 135
            Pseudo Genes (internal stop)      :: 51 of 135
            Pseudo Genes (multiple problems)  :: 46 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10788
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261939-rid24807223.denovo.055"
                     /strain="GPSC323"
                     /isolate="683620"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            145..309
                     /locus_tag="ACL29Z_001768"
     CDS             145..309
                     /locus_tag="ACL29Z_001768"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397534.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GlsB/YeaQ/YmgE family stress response membrane
                     protein"
                     /protein_id="HGR0070032.1"
                     /translation="MGIIANVFAGLVGAYAGQSLLGSWGPSIAGMALLPSIVGAAIVI
                     TVVSFFTGRK"
     gene            393..959
                     /gene="amaP"
                     /locus_tag="ACL29Z_001769"
     CDS             393..959
                     /gene="amaP"
                     /locus_tag="ACL29Z_001769"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000030212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkaline shock response membrane anchor protein
                     AmaP"
                     /protein_id="HGR0070033.1"
                     /translation="MSKAKKICFIIFCILILTIFLPVLIDYHQVSDLGIHLLSWRQNS
                     VVEFYLARYVFWGTVVLSTLVLLSILVVMFYPKRYLEIQLETKNDTLKLKNSAIEGFV
                     RSLVSEHRLIKNPTVHVNLRKNKCFVHVEGKILPSDNIADRCQIIQNEITNGLKQFFG
                     IERQVKLEVAVKNYQPKPQNKKTVSRVK"
     gene            971..1141
                     /locus_tag="ACL29Z_001770"
     CDS             971..1141
                     /locus_tag="ACL29Z_001770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000455065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2273 domain-containing protein"
                     /protein_id="HGR0070034.1"
                     /translation="MEWLKQYRYPIIAGLIGVFLACLIVSFGFFKTIFVLILGALGVA
                     AGLYIEKNYIDK"
     gene            1180..1782
                     /locus_tag="ACL29Z_001771"
     CDS             1180..1782
                     /locus_tag="ACL29Z_001771"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000064115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HGR0070035.1"
                     /translation="MSNEKNTNVEKKDATVVAHEIKGELTYEDKVIQKIIGLSLENVS
                     GLLGIDGGFFSNLKEKIVNSDDVTSGVNVEVGKTQVAVDLNVIVEYQKNVPALYSEIR
                     EIVSSEVAKMTDLEIVEINVNVVDIKTKEQHEADSVSLQDRVSDVAESTGEFTSEQFE
                     KAKSGLGSGFSTVQEKVSEGVEAVKGAANGVVSHENTRVN"
     gene            1813..2016
                     /locus_tag="ACL29Z_001772"
     CDS             1813..2016
                     /locus_tag="ACL29Z_001772"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398938.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CsbD family protein"
                     /protein_id="HGR0070036.1"
                     /translation="MSVEEKLNQAKGSIKEGVGKAIGDEKMEKEGAAEKVVSKVKEVA
                     EDAKDAVEGAVEGVKNMLSGDDK"
     gene            complement(2126..2365)
                     /locus_tag="ACL29Z_001773"
     CDS             complement(2126..2365)
                     /locus_tag="ACL29Z_001773"
                     /inference="COORDINATES: protein motif:HMM:NF025126.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HGR0070037.1"
                     /translation="MNERYQCLKTKEYQALLSSKGRQIFAKRKIDMKSVFGQIKVCLG
                     YKRCHLRGKRQVRIDMGFVLMANNLLKYNKRKRQN"
     gene            2644..2889
                     /locus_tag="ACL29Z_001774"
     CDS             2644..2889
                     /locus_tag="ACL29Z_001774"
                     /inference="COORDINATES: protein motif:HMM:NF033563.0"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HGR0070038.1"
                     /translation="MAESIQGWLAQFLVNLFKSITFDCGKEFSKWKDISNHHDSESFF
                     ANLGCPRQRCLNEHSNRLLRCHDLPKQTDFNEVSQEF"
     gene            complement(3167..3937)
                     /locus_tag="ACL29Z_001775"
     CDS             complement(3167..3937)
                     /locus_tag="ACL29Z_001775"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000229327.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfite exporter TauE/SafE family protein"
                     /protein_id="HGR0070039.1"
                     /translation="MVEIIYFLIIIIASGLGSISGMGGGIIIKPLMDSFGYHSVSDIA
                     FYSSFSVFIMAIISTTKRFSQSKEIKWRLIFTVSFSSVLGGFLGHLIFQVLLSQLSVR
                     LVSIVQMILLFVMLLVSFVLTDFKKTYQFDKIGFYMICGLLLGLISSFLGIGGGPLNV
                     SLLMVFFSISIKEATMYSLAIIFFSQLSHLATIVVVTGLNQYHLAPVPVIFLASICGG
                     VLGTVVSKVLPENWVRYCFKGMLFFVMGMTLYNLFYIL"
     gene            complement(3952..4800)
                     /locus_tag="ACL29Z_001776"
     CDS             complement(3952..4800)
                     /locus_tag="ACL29Z_001776"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000782422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="formylglycine-generating enzyme family protein"
                     /protein_id="HGR0070040.1"
                     /translation="MKMKKIKGGTFMMGTNSEEGFLDDFEGPQVAVSVKDFSIADTPV
                     TNQEFAQFVKETGYKTLAERQEWSFVFILFVPEAEREGYPHPAGAPWWLQVPNACWKH
                     PYGENSNLVGLEDHPVVHVALEDALAFCNWSGMSLPTEAQWEYAARGGRQSEYPWGDT
                     LLEGGYYHANTWQGRFPYENTALDGFIGTAPVYEFLPNDFGLYQMIGNVWEWCRNPIY
                     TLLASFNEDDYELPKYGIQDEEYAIRGGSFLCHCSYCNRYRVAARNGCISTSTSSHLG
                     FRCLKE"
     gene            complement(4797..6272)
                     /locus_tag="ACL29Z_001777"
     CDS             complement(4797..6272)
                     /locus_tag="ACL29Z_001777"
                     /EC_number="3.1.6.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398463.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008484 - sulfuric ester hydrolase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="arylsulfatase"
                     /protein_id="HGR0070041.1"
                     /translation="MVQTKQPNIILIVVDQMRADALSLNSKDKLVSTPTLDMMASVGY
                     NFENAYSPVPSCVPARAALLTGLDQDKSGRVGYQDEVPWNFTNTLPKVFKDMGYQTEC
                     IGKMHVFPSRQRLGFDHVLLHDGYLHVDRKYDKAYGSQFDYASDYLAFLKGKVGYDVD
                     LIDDGMDCNSWEARPWDKDEKLHPTNWVVSESISFLQRRDPTVPFFLKMSFEKPHAPL
                     NPPKYYFDMYMERLPQFLDLHIGNWEVLEKQIPSIYALRGKLKEDDQRRMVAAYFGLI
                     THIDHQISRFLTALKEFRHDKDTIIWFVSDHGDQLGEHYLFRKGYPYQGSIHIPSFIY
                     DPAGLIAGNRGTIKQLVKIQDIFPSLVDLAGGTTTDELDGRSVKNLLFGQYEGWRTEF
                     HGEHALGKDSSQYILTDQWKFIWFPVLNHYQLFDMKKDPHEMNDLYPSEKYQPIVRQM
                     KKKLVDFLRYREEGFVVDEELVPVELSKITPTLTKTGDSQS"
     gene            complement(6595..7950)
                     /locus_tag="ACL29Z_001778"
     CDS             complement(6595..7950)
                     /locus_tag="ACL29Z_001778"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001095003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0016773 - phosphotransferase activity,
                     alcohol group as acceptor [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HGR0070042.1"
                     /translation="MNTMLDKMQEKLSPIAMKVGNQKFLVALRDSFVGTMPVIMTGSI
                     ALLLNAFLVDLPQQFHLESITKTFQWLVDINNLVFKGSIPIVSLLFIYCLGVNIAKIY
                     NVDTVSAGLVSLASFVISIGSTVTKSFPLANVGDVKLDQILQGIDNLAFDGKNLMVTI
                     GNVIPGNHINARGYFTAMMIGFLASIIFCKVMKKNWVIKLPDSVPPAIAKPFTSIIPG
                     FMAMYIVAILTYVFHLLSNDLLIDWVYKVLQTPLLGLSQSFFAVILMIFLNKLFWFFG
                     LHGGNVLAPIMEGLFGVAMLANLDAFQKGEPIPYIWTSGSFGAFVWFGGLGLVLAILI
                     FSRNSHYRKVAKLGLAPVLFNIGEPVNYGLPVVLNPLLFIPFVLSPVFMATVAYWATS
                     WGLVSSVTQNVTWVMPPILYGFFSTAFDWRAIILSVVCLIISVLTYFPFVKMADKTEL
                     S"
     gene            complement(7960..8277)
                     /locus_tag="ACL29Z_001779"
     CDS             complement(7960..8277)
                     /locus_tag="ACL29Z_001779"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000344536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016740 - transferase activity [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HGR0070043.1"
                     /translation="MDESNLESVMGLIMYGGEAKSNAMEAIQAAKKGDFSKANRRLAD
                     ANAALLQAHKAQTEMLTKEAQGEETSISLLMVHAQDHLMTSLTFVDLAKEVVEVYERF
                     EKN"
     gene            complement(8294..8611)
                     /locus_tag="ACL29Z_001780"
     CDS             complement(8294..8611)
                     /locus_tag="ACL29Z_001780"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001151647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HGR0070044.1"
                     /translation="MAKVTIMLACAAGMSTSLLVTKMQKAAEDKGLDAEIFAVPAPEA
                     EEIVATKEVNVLLLGPQVRYLLGDFQEKLKDRQIPVAVIPMTDYGMMNGSKVLDLAES
                     LLD"
     gene            complement(8626..9522)
                     /locus_tag="ACL29Z_001781"
     CDS             complement(8626..9522)
                     /locus_tag="ACL29Z_001781"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="haloacid dehalogenase-like hydrolase"
                     /protein_id="HGR0070045.1"
                     /translation="MKRLISANPSEILQMNAEELKQSILASEGRVVLSENVVTRETFV
                     GDITNSEIARAFGADMILLNCVDVFEPKIYALDSSGDDVIHRLHQLVACPIGVNLEPI
                     DPSAKMLEETQEIVAGRVASVETLNRIEELGFDFVCLTGNPGTGVSNREIIKAVQTAK
                     ENFSGLIIAGKMHGAGVNEPVAELSVAEQLLEAGADVILVPAVGTVPAFHDQELREVV
                     DLVHSKGGLVLSAIGTSQETSDTDTIKEIALRNKICGVDIQHIGDAGYGGLATVDNIY
                     ALSKVIRGVRHTVSRLARSVNR"
     gene            complement(9525..10787)
                     /locus_tag="ACL29Z_001782"
     CDS             complement(9525..10787)
                     /locus_tag="ACL29Z_001782"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000413340.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0016773 - phosphotransferase activity,
                     alcohol group as acceptor [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HGR0070046.1"
                     /translation="MEKLLQEKLLPVAARLGNNKALVSIRDGITLTIPLLLIGSLLMV
                     IASFPIPGWEKYLGDIGVADYLWKGVDSSFGLLGLVASFGIAYFMARQYKVDGIPAGI
                     VSLSSFITVTPFIRGEAGAGMPTAFMASKGLFVAMILGLINGYIYQWFINHNIQIKMP
                     DGVPPAVSKSFSAIIPGAVTIVGWLIVYATLDKLSLPNLHEIAQVALGGPLGLLGNNV
                     IGLLILIFLNSSFWFVGLHGGNVVNAVMKPLWLANLDANKVAYQTGETLPNIFTSVFM
                     DNFVFIGGGGATIGLVLALGYLAHKKKASKQLKTLAPITVIPGLFNINEPAMFGVPIV
                     LNILLLVPFILAPMFNLLVAWGAMASGLVPLTYTDPGWTMPPVISGLLATGSISGSLL
                     QIVLIVLDVLLYLPFVIAIEKRFKLLED"
BASE COUNT         3723 a         2172 c         1667 g         3226 t
ORIGIN      
        1 tattaaagtt atataatagt attaatcaaa gaaattgatt ttttgatatt aaaataaaaa
       61 aggagggtag gcagtgttgt gatcaattat tgctggaggt cttattggtc tcttggcagg
      121 taaaatcact aaaaaagtag ttctatggga atcatcgcaa atgtattcgc tggtttagtc
      181 ggggcatatg caggacaatc tcttttaggt agttggggtc catcaatcgc tggaatggct
      241 ttgctcccat ctattgtagg tgcagcgatt gtgattactg tagtgtcatt ctttacaggt
      301 agaaagtaaa cttttcgcca gtaaagttag caaactattt ttaaatcaat gacgggaaaa
      361 atagtttaaa tgttaaatcg aaaggattgt atatgtcaaa agcaaagaaa atatgtttca
      421 ttattttctg tattttaatc ttgacaattt tccttcctgt tttgatagat tatcatcaag
      481 ttagtgatct aggtattcat ctacttagct ggagacagaa ctccgtagtt gaattctatc
      541 ttgctagata tgtcttttgg gggacagtgg ttctatcaac tttagtttta ttatccattt
      601 tagttgtgat gttttatcct aaacgttact tggaaatcca acttgaaact aaaaacgata
      661 cattaaaatt aaagaattcg gcaatcgaag gttttgttag aagtttggtg agtgagcata
      721 gattgatcaa gaatccaact gttcatgtaa atttacgaaa aaataaatgt ttcgttcatg
      781 tagaaggtaa aattcttcct tcagacaaca tcgctgacag atgccaaata attcaaaatg
      841 aaataactaa tggattgaag cagttttttg gtattgagcg tcaagtaaaa cttgaagttg
      901 cagtaaaaaa ttaccaacca aaacctcaaa acaaaaagac tgttagtcgt gtgaagtaag
      961 gaagtaaaaa atggaatggc ttaaacaata tcgatatcca attatcgctg gtctcatagg
     1021 cgtatttctg gcttgtttga ttgtctcctt tggcttcttc aaaacaatat ttgtattgat
     1081 tttaggagca ctgggagttg cagctggatt atatatcgaa aaaaactata tagataaata
     1141 aaaaaataaa aattactaat ttaattaaag gagtttcata tgtcaaacga aaaaaacact
     1201 aacgtagaaa agaaagatgc tactgttgta gctcacgaaa tcaaagggga acttacttac
     1261 gaagataaag ttatccaaaa aatcattggt ctttcactag aaaacgtttc aggtcttttg
     1321 ggaatcgatg gtggtttctt ctcaaatctt aaagaaaaaa tcgttaacag cgatgacgta
     1381 acaagtggtg ttaacgtaga agttggtaaa acacaagttg cagttgactt aaacgttatt
     1441 gttgagtacc aaaaaaatgt tccagcttta tattcagaaa tcagagaaat cgtatcttca
     1501 gaagttgcta aaatgactga cttggaaatt gttgaaatca acgtaaacgt tgtcgacatc
     1561 aaaactaaag aacagcatga agcagactca gtaagccttc aagatcgcgt atctgacgtt
     1621 gctgaatcaa caggagaatt cacttcagaa caattcgaaa aagctaaatc tggtcttgga
     1681 tctggtttct caactgttca agaaaaagtt agcgaaggtg tagaagctgt taaaggtgca
     1741 gcaaatggtg tagtatctca cgaaaacact cgtgtaaact aagataaaat aaatataaca
     1801 ggagaaatta tcatgtcagt agaagaaaaa ttaaatcaag ctaaaggttc tattaaagaa
     1861 ggtgttggga aagccatcgg tgatgaaaaa atggaaaaag aaggagcagc tgaaaaagtt
     1921 gtttctaaag taaaagaagt tgccgaagac gctaaagacg ctgtagaagg tgctgtagaa
     1981 ggtgttaaaa acatgttgag tggcgacgat aaataaggtt aaaagttact ttatcttttt
     2041 agtaatatta gtcaaaagag tctgagtcaa gatgattctc agaaaacaaa aagctagaga
     2101 ttcccaattg cggaactcta gctttttaat tttgcctctt tctcttatta tatttcagca
     2161 ggttgttggc catgagtacg aatcccatgt caattctcac ttgacgctta cctctcagat
     2221 gacatctctt ataacccaaa caaaccttta tctgcccaaa gacagatttc atatcaatct
     2281 tacgtttagc gaaaatttgt ctacccttgg aagataaaag tgcctgatat tctttagttt
     2341 ttaaacactg gtaacgttca ttcatataca gtcccttttg aggggctgat tcaggttcat
     2401 aatcgcagtc aacattgatt tcaaggctgt ttgctttcta tctccccttt ttcatgatat
     2461 attttcgtac aggttcttca atagtttcta tagtaaaatg aaccaaaaat agtacacgtt
     2521 gcggtataat gttcttgtgg catattcatt agattttcgt aaaaagttct ctcctatttg
     2581 tgagcgaaca ggtatagtca attgattgtc agtttgaaga ccaagagtcg taaggcaaag
     2641 gatatggcag aatccatcca agggtggcta gcacaatttc tagtgaatct ctttaaatct
     2701 attacgtttg actgtggaaa agagttttca aaatggaaag atatttccaa tcatcacgat
     2761 agtgagagct tttttgcgaa tctaggatgt ccaagacagc ggtgtctcaa cgaacattca
     2821 aatagacttt taaggtgtca tgacttgcca aagcagacag atttcaacga agtcagtcaa
     2881 gaattttagg ctggacaaaa actcaatttc aggagaaaat gaaataaata ttcccacaat
     2941 aaaacgcata gtatcaaagt ttttccaaca cctgatatta tgcatttttt aattttaaag
     3001 actttttccc agcctcaaga aatcacatcc cacctaaatc ctttggatac caaatacctc
     3061 atcaggtatt ttctgagttg gtaagactgt ctagattaat ttgacaaatg gagggcgtta
     3121 aatccagttt ttacaggaag tctatttaaa tattttcaca ctgaccttac aaaatataaa
     3181 ataaattata taaagtcatt cccatgacaa agaataacat ccctttaaaa cagtatctta
     3241 cccaattttc aggtaagact tttgatacaa ccgtccccaa tacccctccg catatagaag
     3301 caagaaaaat aactggaaca ggtgctaaat gatactgatt taaacctgta accacaacaa
     3361 ttgtagccaa atgagacagc tgggaaaaga aaataattgc aagagaatac atcgttgctt
     3421 cttttatcga aatagaaaaa aacaccatca ataaagatac attgagcgga ccaccaccaa
     3481 tccctaaaaa actagaaatt aagcccaata gaagaccaca aatcatatag aatcctatct
     3541 tatcaaattg ataagttttt ttaaaatctg ttaaaacaaa tgatacaagt agcatcacaa
     3601 atagtaaaat catttgaaca atggatacta gccgtactga taactgagat aacaaaactt
     3661 gaaaaataag atgacctaga aatcctccta aaacagaaga aaaggatacc gtaaaaatca
     3721 atctccattt tatctcttta ctttgtgaaa atcttttggt tgttgaaata atcgccatta
     3781 taaaaacaga gaaactagaa taaaaagcaa tatcactgac cgaatggtat ccaaaactat
     3841 ccataagtgg cttaattata attccaccac ccatgcctga tatagaaccc aatccactag
     3901 ctattataat gattagaaaa taaataatct caaccacttt ttaagtccat cctattcttt
     3961 caaacatcta aaacctagat ggctactagt ggaagtagaa atacatccat ttctagcagc
     4021 tactcggtat cgattacaat aagaacaatg acataaaaag gaacctcctc tgatagcata
     4081 ctcctcatct tgtatcccat attttggcaa ctcatagtca tcttcattaa aactagctaa
     4141 taaggtatat atcggattgc gacaccattc ccaaacattt ccaatcattt gatatagacc
     4201 aaaatcatta ggtaaaaatt catagacagg agccgttcct ataaatccat ctaaggcagt
     4261 attttcataa ggaaatcttc cttgccaagt attggcatga taatatccac cttctaaaag
     4321 agtatctccc caaggatatt cagattgtct tcctcctcta gcagcatatt cccactgtgc
     4381 ttcagtcggt aaagacattc cgctccaatt acagaaagcc aatgcatctt ctaaagcaac
     4441 atgaactact ggatggtctt ctaaacccac tagattactg ttctcaccgt agggatgttt
     4501 ccagcaagcg ttcggaactt gtaaccacca cggagcccca gcaggatgag gatatccctc
     4561 cctttctgcc tctggaacga acaatataaa aacaaaagac cactcttgtc gctcagctag
     4621 tgttttatag cctgtttctt tcacaaattg agcaaattct tgattcgtaa ctggagtatc
     4681 cgcaatggaa aaatccttta cactaacagc gacttgagga ccttcaaaat catctaaaaa
     4741 gccctcttca gaatttgttc ccatcataaa tgtcccaccc ttgatttttt tcattttcat
     4801 gattgactat cccccgtttt cgttagagtt ggcgttattt tagaaagttc aacaggaact
     4861 aactcttcat ccacaacaaa accttcttct ctatatctaa gaaagtctac taattttttc
     4921 ttcatctgac gaacaatagg ttgatatttt tcacttggat acaaatcatt catttcatgc
     4981 ggatcttttt tcatatcaaa taactgataa tgatttaaaa caggaaacca gataaatttc
     5041 cactggtctg tcaagatata ttgactagaa tcttttccta aagcatgttc accatgaaat
     5101 tctgttcgcc acccctcgta ctgtccaaat aataaattct taacactccg tccatctagt
     5161 tcatctgtag tagttcctcc tgccaaatcc acgagtgaag gaaaaatatc ttgaattttc
     5221 actaattgct tgattgttcc cctattacca gctatcaatc cagccggatc gtaaataaac
     5281 gaaggaatgt ggatacttcc ctgataagga tatccctttc taaacagata atgttcacca
     5341 agctgatctc catgatccga aacaaaccag ataatcgtat ctttatcatg acgaaattct
     5401 tttagggcag tcaaaaagcg actaatttga tggtctatat gagtaatcaa tccaaaataa
     5461 gcagcaacca ttcttctttg atcatcttcc tttaatttcc ctcttaaagc ataaatagac
     5521 ggaatttgct tttctaatac ttcccaattc ccgatatgca aatcgagaaa ttgaggcaag
     5581 cgttccatat acatatcaaa atagtatttt gggggattta atggagcatg tggtttttca
     5641 aaagacattt tgagaaaaaa aggaaccgtt ggatctcttc tttgtaaaaa tgaaatagac
     5701 tcactcacaa cccagtttgt tggatgtaac ttctcatctt tatcccaagg tctagcttcc
     5761 caagaattac aatccattcc gtcatcaatt aaatcaacat cataaccaac tttacccttt
     5821 aaaaaggcta gatagtcact agcataatca aattgacttc cataagcctt atcatacttt
     5881 ctatcaacat gtagataccc atcgtgaagt aagacatgat caaacccaag tctctgtctg
     5941 gaaggaaaaa catgcatctt accaatacac tctgtttgat aacccatatc tttaaagact
     6001 tttggaagag tattagtaaa attccaaggc acctcatctt gataaccaac tcgtccactt
     6061 ttatcttggt ctaagccagt caataaagct gccctagcag gaacgcaaga aggaactgga
     6121 gaataggcat tttcaaaatt ataacctaca ctagccatca tatctaatgt tggagtgcta
     6181 actagcttat ccttactatt caaggataag gcgtctgctc tcatttgatc tacaacaatc
     6241 aaaataatat ttggctgttt tgtctgaacc ataaaatctc ctttctaata tggcaaaaga
     6301 ggcacaagaa gatatctacc tttactgcac ccctttctat atcaatctct ctatataaaa
     6361 caataacatt cttgttatgt tttatagaaa aatgaactaa aatatgacta aatcgattag
     6421 gaaattcaaa tcattttcta gtactgtttt agaagttaca gtgtactatt ccaacttcaa
     6481 taaattataa acctttgtct aataacaatt ttagtggaga taagaaatcc tacacctaac
     6541 tcatcttaca cgtaatctat ttctatttta tcacaaaaaa cgcaagtaag accattaact
     6601 caattcagtt ttatctgcca ttttcacaaa tgggaaataa gtcaagacac taataatcaa
     6661 acaaacaact gataagatga tggcacgcca atcaaatgct gtagagaaga aaccatataa
     6721 aattggcggc attacccaag taacattttg tgtaacagat gaaacaagac cccagcttgt
     6781 tgcccagtaa gctaccgttg ccatgaaaac cgggctaagt acaaatggta taaatagcaa
     6841 aggattcaag acaactggta aaccataatt gaccggctca ccaatattaa acagaactgg
     6901 tgctagacca agtttagcaa cttttcgata atgactgttt cttgaaaaaa ttaaaatagc
     6961 aagtactaat cctaatcctc caaaccagac aaacgcccca aaagacccac ttgtccatat
     7021 ataaggaatc ggttcacctt tttggaaagc atccagattc gctaacatag caactccaaa
     7081 cagcccttcc atgatgggag ccaatacatt tcctccatgg agaccaaaaa accagaataa
     7141 cttattcaaa aagatcatca gaataactgc aaagaaactt tgagacaaac ctagtaatgg
     7201 cgtttgtaac accttgtaaa cccaatcaat caataagtca ttgctaagta aatggaaaac
     7261 ataagtcaag atagctacta tatacatcgc cataaatcct ggaatgatag aagtgaacgg
     7321 cttagcaatc gcagggggaa ctgaatctgg taacttgatt acccagttct ttttcattac
     7381 tttacagaaa ataatagagg ctaaaaatcc aatcatcatg gctgtaaagt agcctctggc
     7441 attaatatgg tttcctggaa tcacattccc aatagttacc atcagatttt taccatcaaa
     7501 tgctagatta tcaattcctt gtaagatttg atctaatttc acatctccta catttgccaa
     7561 agggaaactc tttgtaactg tacttccaat cgaaatgaca aacgaagcaa gtgataccaa
     7621 accagcagaa actgtatcaa cattgtaaat cttagcgata ttcactccca agcaatagat
     7681 gaacaacaag gaaacaattg gtatacttcc cttgaatacc aaattattga tgtcaacaag
     7741 ccactgaaag gttttcgtaa tactttctag gtgaaattgt tgtggtaaat ccactagaaa
     7801 agcatttaat aacaaagcaa tggaacctgt cataataaca ggcatagtcc ccacaaatga
     7861 atcacgtaaa gcaactaaaa acttctgatt cccaactttc attgcaattg gagaaagttt
     7921 ttcttgcatt ttatccaaca ttgtattcat accaaactcc taattttttt caaatcgttc
     7981 gtatacttct accacttctt tcgccaagtc aacaaaggtc agactcgtca ttaaatgatc
     8041 ttgcgcgtgt accatcaaga ggctaattga tgtttcttcc ccctgtgcct cttttgtcaa
     8101 catttctgtt tgagccttat gcgcctgtaa taaggcagca ttcgcatcag ctaatcttcg
     8161 attggcttta gagaaatccc ctttttttgc tgcctgaata gcctccatag cattactttt
     8221 ggcttcccca ccatacataa ttagccccat tacagattct aaattacttt catccataac
     8281 attctcctca atcttagtct aataaacttt cagctaaatc taagacttta gaaccattca
     8341 tcattccata atctgtcatc ggaataaccg ccacaggaat ctgtctatct tttagttttt
     8401 cttgaaagtc ccctagtaaa tagcgaactt gagggcctaa aagcaacaca tttacttctt
     8461 ttgttgctac aatttcttct gcttcaggag ctggaactgc aaaaatttct gcatccaacc
     8521 ccttatcttc tgctgccttt tgcatctttg tcactagcag acttgtactc atacctgctg
     8581 cacatgctaa cataattgtt actttagcca tagcttactc ctttatcacc tatttactga
     8641 cctagccaag cgagatactg tatgtctcac tcctctaatt accttgctca atgcataaat
     8701 attatcgact gttgccagtc ccccatatcc tgcgtcacct atatgttgaa tatcaactcc
     8761 acaaatttta tttctaagtg caatttcctt gatagtatct gtatcagatg tttcttggct
     8821 agtaccaata gcactcagta ctagcccacc cttactatga acgagatcaa cgacttcacg
     8881 caactcttgg tcatgaaagg ctggaacggt tccaactgct ggaacaagta tcacatccgc
     8941 acctgcttcc aacaattgct ctgctacaga aagctctgcc acaggctcat tcactcctgc
     9001 cccgtgcatc ttacctgcaa taatcaaacc agaaaagttt tccttagcag tttgaacagc
     9061 cttaatgatt tctcgattgc taactcctgt tccaggattt ccagtcaaac agacaaagtc
     9121 aaaacctaac tcctctattc gattcaatgt ttcaacacta gcaacacgac ctgcaacaat
     9181 ttcctgtgtt tcctctagca tctttgcaga tgggtcaatc ggttccaaat ttacaccaat
     9241 tggacaagca acaagctggt gtaagcgatg aataacatca tcacctgaac tatccaaagc
     9301 ataaatttta ggctcaaaaa catcaacaca attcaataaa atcatatcag ctccaaaagc
     9361 tctagcaatt tcagaattag ttatatcccc aacaaatgtc tcacgagtaa ctacattttc
     9421 agatagaaca actctacctt cacttgctaa aatactttgt tttaattctt cagcattcat
     9481 ctgtaatatc tcagatggat ttgcactaat taaacgtttc attctcaatc ctccaataac
     9541 ttaaaccgtt tttcaatagc tattacaaat ggtaaataaa gtaagacatc caaaacaatc
     9601 aatacaattt gtaataatga accagaaata cttcctgtag caagtaaacc acttataaca
     9661 ggtggcatag tccaacctgg atctgtataa gttagcggaa ccaaacctga tgccattgct
     9721 ccccacgcta ctagtaagtt aaacattgga gctaagataa atggaactag taacaaaatg
     9781 ttcaaaacaa taggaacacc aaacattgct ggttcattta tattaaataa tccaggtata
     9841 acagttatag gtgccaaagt ttttagttgt ttactagctt tcttcttatg tgctaaatat
     9901 cctaacgcaa gaactaaacc tatggttgca ccaccgccac ctatgaatac aaaattatcc
     9961 ataaatacgc tagtaaaaat atttggaaga gtttctccag tttgataagc tactttattt
    10021 gcatctagat tagctaacca taacggtttc ataactgcat taacaacatt tcctccgtgt
    10081 aatcctacaa accaaaaact actattaagg aaaattaaga taagaagacc aataacatta
    10141 tttcctaaaa gtccaagtgg acctcccaaa gctacttgag caatttcatg aagattaggt
    10201 aaacttaatt tatctaaagt tgcataaaca atcaaccaac caacaatagt cactgcacca
    10261 ggaataatgg cactaaagct tttagatact gctggtggaa caccatccgg catttttatc
    10321 tgtatattat gatttataaa ccattggtag atatagccat taatcaatcc taaaatcata
    10381 gcaacaaata aaccttttga tgccatgaaa gcggtaggca ttcctgctcc agcctctcct
    10441 ctaatgaaag gcgtaactgt aataaaagat gataatgaca caataccagc aggaatacca
    10501 tcaactttgt attgtctagc cataaagtaa gcgataccaa aactagctac aagaccaagt
    10561 aatccaaaac tactatcaac acccttccat aaatagtcag caacaccaat atcacccaga
    10621 tatttttccc atcctggaat aggaaaactt gcaataacca ttagtaatga acctatcaac
    10681 aataaaggta tagttagagt aataccgtct cgaatagaaa ccaacgcttt attattaccc
    10741 aatctagccg ctactggaag taacttttct tgtaataatt tttccata
//
LOCUS       DBEJAU010000056        10725 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC323 isolate 683620
            SAMN38261939-rid24807223.denovo.056, whole genome shotgun sequence.
ACCESSION   DBEJAU010000056 DBEJAU010000000
VERSION     DBEJAU010000056.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261939
            Sequence Read Archive: SRR26833919
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 10725)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10725)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576303.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576303.1
            Genome Coverage       :: 154x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/19/2025 01:05:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,121
            CDSs (total)                      :: 2,078
            Genes (coding)                    :: 1,943
            CDSs (with protein)               :: 1,943
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 36
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 72 of 135
            Pseudo Genes (incomplete)         :: 63 of 135
            Pseudo Genes (internal stop)      :: 51 of 135
            Pseudo Genes (multiple problems)  :: 46 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10725
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261939-rid24807223.denovo.056"
                     /strain="GPSC323"
                     /isolate="683620"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            complement(87..1511)
                     /locus_tag="ACL29Z_001783"
     CDS             complement(87..1511)
                     /locus_tag="ACL29Z_001783"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000199391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-dependent glyceraldehyde-3-phosphate
                     dehydrogenase"
                     /protein_id="HGR0070047.1"
                     /translation="MTRYQNLVNGKWKSSEQEITIYSPINQEELGTVPAMTQTEADEA
                     MQAARAALPAWRALSAIERAAYLHKTAAILERDKEKIGTILAKEVAKGIKAAIGEVVR
                     TADLIRYAAEEGLRITGQAMEGGGFEAASKNKLAVVRREPVGIVLAIAPFNYPVNLSA
                     SKIAPALIAGNVVMFKPPTQGSISGLLLAKAFEEAGIPAGVFNTITGRGSEIGDYIIE
                     HKEVNFINFTGSTPIGERIGRLAGMRPIMLELGGKDAALVLEDADLEHAAKQIVAGAF
                     SYSGQRCTAIKRVIVLESVADKLATLLQEEVSKLTVGDPFDNADITPVIDNASADFIW
                     GLIEDAQEKEAQALTPIKREGNLLWPVLFDQVTKDMKVAWEEPFGPVLPIIRVASVEE
                     AIAFANESEFGLQSSVFTNDFKKAFEIAEKLEVGTVHINNKTQRGPDNFPFLGVKGSG
                     AGVQGIKYSIEAMTNVKSIVFDVK"
     gene            complement(2056..4335)
                     /gene="pulA"
                     /locus_tag="ACL29Z_001784"
     CDS             complement(2056..4335)
                     /gene="pulA"
                     /locus_tag="ACL29Z_001784"
                     /EC_number="3.2.1.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000283081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0051060 - pullulanase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type I pullulanase"
                     /protein_id="HGR0070048.1"
                     /translation="MYNYPMRIHYHRKNGEYDTCSFVKSQDQRIDLLTYKEDYFGALF
                     SFEHPSSHVIESLNFVVHTGQTSKEYSIRFNHYPLLTEVWILEGDDRIYYSENPAIAS
                     PFYKNQNPFAFDKAINSASFDHHWGYQGELGCRVEDNQAHFSLWSPTATEVQVVVYES
                     AANDAPVWKTFEMKRGNSYSYNHKDNTIGVWSLDVEEDLVGKTYQYQVQFPHHQTLTR
                     DPYTIATSPDGKRSAILSHVEKQVENFEVKHGSEATWRLENPCKAVICEMHIRDLTKS
                     PTSGVDEHLRGTFLGAAQAGTVNQYGQSTAFDYIKKLGYNYVQLQPIADRHKEYDEDG
                     NVTYNWGYDPQNYNAPETSFSTNSDDPAQVIRDLKVMVQAYHDAGIGVIMDVVYNHTF
                     SVVDAPFQTTVPDYYYRMNPDGTFQNGTGVGNETASEHEMFRKYMIDSLLYWVQEYNI
                     DGFRFDLMGIHDVKTMQMIRQSLDEIDSNIILYGEGWDMGTGLAPYDKAKKDNAYQMP
                     NIGFFNDNQRDAVKGGEVYGAIKSGFVSGAATEPILAKAILGSRELGTYTHPNQVLNY
                     VEAHDNYNLHDLLATLHPDQSSEQIMRKVETATAMNLLMQGMAFMEIGQEFGRTKLVA
                     TGENGELTHDDRERAMNSYNAPDSVNQVNWNLINERQDSIEFIRQVIRLKTKTGAFSY
                     SSYDEIYHHVFVHSAIEHSGCLIYEVHGKEHLLVVVNAKSEPYQFENAGNLAMLVTNS
                     RSKEDNVLNDISLAVLSVL"
     gene            complement(4447..6405)
                     /gene="ligA"
                     /locus_tag="ACL29Z_001785"
     CDS             complement(4447..6405)
                     /gene="ligA"
                     /locus_tag="ACL29Z_001785"
                     /EC_number="6.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001042597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003911 - DNA ligase (NAD+) activity
                     [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent DNA ligase LigA"
                     /protein_id="HGR0070049.1"
                     /translation="MNKRMNELVALLNRYATEYYTSDNPSVSDSEYDRLYRELVELET
                     AYPEQVLADSPTHRVGGKVLDGFEKYSHQYPLYSLQDAFSREELDAFDARVRKEVAHP
                     TYICELKIDGLSISLTYEKGILVAGVTRGDGSIGENITENLKRVKDIPLTLPEELDIT
                     VRGECYMPRASFDQVNQARQENGEPEFANPRNAAAGTLRQLDTAVVAKRNLATFLYQE
                     ASPSTRDSQEKGLKYLEQLGFVVNPKRILAENIDEIWNFIQEVGQERENLPYDIDGVV
                     IKVNDLASQEELGFTVKAPKWAVAYKFPAEEKEAQLLSVDWTVGRTGVVTPTANLTPV
                     QLAGTTVSRATLHNVDYIAEKDIRKDDTVIVYKAGDIIPAVLRVVESKRVSEEKLDIP
                     TNCPSCNSDLLHFEDEVALRCINPRCPAQIMEGLIHFASRDAMNITGLGPSIVEKLFA
                     ANLVKDVADIYRLQEEDFLLLEGVKEKSAAKLYQAIQASKENSAEKLLFGLGIRHVGS
                     KASQLLLQYFHSIENLYQADSEEVASIESLGGVIAKSLQTYFATEGSEILLRELKETG
                     VNLDYKGQTVVADAALSGLTVVLTGKLERLKRSEAKSKLESLGAKVTGSVSKKTDLVV
                     VGADAGSKLQKAQELGIQVRDEAWLESL"
     gene            complement(6498..7676)
                     /locus_tag="ACL29Z_001786"
     CDS             complement(6498..7676)
                     /locus_tag="ACL29Z_001786"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001083019.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HGR0070050.1"
                     /translation="MNRYAVQLISRGAINKMGNMLYDYGNSVWLASMGTIGQTVLGMY
                     QISELVTSILVNPFGGVISDRFSRRKILMTADLVCGILCLAISFIRNDSWMIGALIVA
                     NIVQAIAFAFSRTANKAIITEVVEKDEIVIYNSRLELVLQVVGVSSPVLSFLVLQFAS
                     LHMTLLLDSLPFFIAFVLVAFLPKEEAKVQEKKAFTGRDIFVDIKDGLHYIWHQQEIF
                     FLLLVASSVNFFFAAFEFLLPFSNQLYGSEGAYASILTMGAIGSIIGALLASKIKANI
                     YNLLILLALTGVGVFMMGLPLPTFLSFSGNLVCELFMTIFNIHFFTQVQTKVESEFLG
                     RVLSTIFTLAILFMPIAKGFMTVLPSVHLSSFLIIGSGVIILSCISFIYVRTHFEKLI
                     "
     gene            complement(7756..8619)
                     /locus_tag="ACL29Z_001787"
     CDS             complement(7756..8619)
                     /locus_tag="ACL29Z_001787"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012291596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XRE/MutR family transcriptional regulator"
                     /protein_id="HGR0070051.1"
                     /translation="MEHLGKVFREFRTSGNYSLKEAAGESCSTSQLSRFELGESDLAV
                     SRFFEILDNIHVTIENFMDKARNFHNHEHVSMMAQIIPLYYSNDIAGFQKLQREQLEK
                     SKSSTTPLYFELNWILLQGLICQRDATYDMKQDDLDKVADYLFKTEEWTMYELILFGN
                     LYSFYDVDYVTRIGREVMEREEFYQEISRHKRLVLILALNCYQHCLEHSSFYNANYFE
                     AYTEKIIDKDIKLYERNVFHYLKGFALYQKGQCKEGCKQMQEAIHIFDVLGLPEQVAY
                     YQEHYEKFVKS"
     gene            complement(8622..10523)
                     /locus_tag="ACL29Z_001788"
     CDS             complement(8622..10523)
                     /locus_tag="ACL29Z_001788"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000584877.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HGR0070052.1"
                     /translation="MIILQANKIERSFAGEVLFDNINLQVDERDRIALVGKNGAGKST
                     LLKILVGEEEPTSGEINKKKDISLSYLAQDSRFESENTIYDEMLHVFNNLRRTERQLR
                     QMELEMGEKSGEDLDKLMSDYDRLSENFRQAGGFTYEADIRAILNGFKFDESMWQMKI
                     AELSGGQNTRLALAKMLLEKPNLLVLDEPTNHLDIETIAWLENYLVNYSGALLIVSHD
                     RYFLDKVATITLDLTKHSLDRYVGNYSRFVELKEQKLVTEAKNYEKQQKEIAALEDFV
                     NRNLVRASTTKRAQSRRKQLEKMERLDKPEAGKKAANMTFQSEKTSGNVVLTVENTAI
                     GYDGEVLSQPINLDLRKMNAVAIVGPNGIGKSTFIKSIVDQIPFIKGEKRFGANVEVG
                     YYDQTQSKLTPSNTVLDELWNDFKLTPEVEIRNRLGAFLFSGDDVKKSVGMLSGGEKA
                     RLLLAKLSMENNNFLILDEPTNHLDIDSKEVLENALIDFDGTLLFVSHDRYFINRVAT
                     HVLELSENGSTLYLGDYDYYIEKRATAEMSQTEEASTSNQAKEASPVNDYQAQKESQK
                     EVRKLMRQIESLEAEIEELESQSQAISEQMLETNDADKLMELQAELDKISHRQEEAML
                     EWEELSEQV"
BASE COUNT         3217 a         2365 c         1911 g         3232 t
ORIGIN      
        1 accaaaaagt tcgtattttt tctataatta ttattatttt atagcaaaaa aataaaacca
       61 ggaaaacaat ttcctgattt tacacgttat ttcacatcaa aaacaatgga tttgacattt
      121 gtcatcgctt caatgctata tttaatccct tgcactccag ctccagaacc tttgacacca
      181 aggaacggga aattatctgg accacgctgg gttttattat taatgtggac tgtacctact
      241 tcaagttttt cagcaatttc aaaggctttt ttgaaatcat ttgtaaagac tgatgattga
      301 aggccgaatt cagattcgtt ggcaaaggca atagcttcct ctacactagc cacacgaatg
      361 attggtaaaa caggaccaaa tggctcttcc catgccactt tcatatcttt tgtaacttgg
      421 tcaaaaagca ctggccagag aagattgccc tcacgtttga ttggtgtaag agcctgagcc
      481 tctttttctt gtgcatcctc aatcaagccc caaatgaagt cggctgaagc attgtcaata
      541 acaggtgtaa tatcagcatt gtcaaatgga tcaccaactg ttaatttaga aacttcttcc
      601 tgaagcaaag tagctaattt atctgctaca ctttcgagaa caatgacacg tttaatggcc
      661 gtgcaacgtt gtcctgagta gctaaaggct cctgcaacaa tttgcttggc agcatgttcc
      721 aaatctgcat cttctagtac aagagctgca tctttcccac caagttccaa catgatagga
      781 cgcataccag ctaaacgacc aatacgttct ccaatagggg ttgaacctgt aaagttgatg
      841 aagttgactt ctttgtgctc aatgatataa tccccaattt ctgaaccacg acctgtaatg
      901 gtgttgaaaa cacctgccgg aatccctgct tcttcaaatg ctttagccaa caagagtcca
      961 gaaatggaac cttgtgttgg tggcttaaac atgaccacat tccctgcaat caaggcaggt
     1021 gcaattttag aagcagataa attaactgga taattaaagg gagcaatcgc tagcacgata
     1081 ccaactggtt cacgacggac aacagccagt ttgtttttac ttgctgcctc aaaaccacca
     1141 ccttccattg cttgtccagt gatacggaga ccttcctcag cagcataacg aatcaagtct
     1201 gctgtacgca ctacttctcc aattgctgct ttaatccctt ttgctacttc tttggcaagg
     1261 atagtaccaa ttttttcctt atcgcgttct aaaatagctg ctgttttatg caaataagcc
     1321 gcacgttcaa ttgctgataa agctcgccat gctggcaggg ctgcacgcgc agcttgcata
     1381 gcctcatcag cttcagtctg agtcatggct ggaactgtac ccaattcttc ttgattgatt
     1441 ggtgaataaa tcgtaatttc ttgttcagat gatttccatt ttccatttac taaattctga
     1501 tatcttgtca aattcttgtc ctcctgaaaa tgattaagat atattttacc aaattttcag
     1561 aaaatcacaa ccctttttgc aaaatttttg agattatttt cacaagcttg atttttcaaa
     1621 gtatactcaa taaaaataaa aaaaatccac tacatcaagg cgagactaat gtggtttgaa
     1681 gaaattttcg aagagcgtga atgagtatca tctatagtaa aataaaaaaa ctgaacaatt
     1741 tggttgggga cagccaaacc aatttctcac aatgtttcag aaacaagggt gtgctattcc
     1801 aatttcagcc tactataact gtcatagatt gctgaaacaa agtctaggta aaagtcttca
     1861 taataaaaag acctcctatc aaatgttcaa aaactttgat aggaggtctt gtttcgtgaa
     1921 aacatttatc aaattttcta tacaagtgag ctgttagcca ggttctttct attctttcaa
     1981 tttcaatgaa tggatttttt accaatactc ataactggga atttttctgt ctaaaaatag
     2041 cgagatagat ggtatttata aaacactcaa gacagctaga ctaatatcat ttaaaacatt
     2101 atcttctttt gagcgactgt tggttaccaa catagctaaa tttcctgcat tttcaaattg
     2161 atagggttct gatttagcat tcacaaccac caagaggtgt tctttgccgt gaacttcata
     2221 gataaggcag ccgctatgtt caatcgcaga atgcacaaag acatgatggt aaatttcatc
     2281 atagctagag taagaaaagg caccagtttt tgtcttcaat cggatgactt gacggataaa
     2341 ctcaatactg tcttgacgct cattaatcaa gttccagttc acttggttca cactgtcagg
     2401 agcattatag ctattcatcg cacgctctct atcatcatgg gtcaactcac cattttcacc
     2461 agtcgcaacc agtttggtac gaccaaattc ttgaccgatt tccataaagg ccatcccctg
     2521 catgagcaga ttcatggctg tggcagtttc gaccttgcgc atgatttgct ctgaactttg
     2581 gtctggatga agggttgcca ataaatcgtg aagattgtaa ttgtcatggg cttctacata
     2641 gttaagcacc tgatttggat gtgtataggt tcctaattca cgacttccta ggattgcttt
     2701 agctagaatt ggctctgtcg cagcaccact gacaaaacct gacttgatag caccataaac
     2761 ttctccccct ttgacagcat cgcgctgatt gtcattaaag aaaccaatat ttggcatctg
     2821 gtaggcattg tccttcttgg ccttatcata aggggcaaga cctgttccca tatcccatcc
     2881 ttctccatag aggataatgt tggagtcgat ttcatccaag ctttgacgaa tcatctgcat
     2941 ggtcttgaca tcatgaatcc ccatcaagtc aaaacggaag ccgtcaatat tatattcctg
     3001 cacccagtat agaagagaat caatcatata cttgcgaaac atttcgtgtt cactggctgt
     3061 ttcatttcca acacccgttc cattctggaa ggtaccatct ggattcatac gataatagta
     3121 atcagggact gttgtttgga atggtgcatc aacaactgag aaggtatggt tatagactac
     3181 atccataatg actccaatac ccgcatcgtg ataagcttga accatcacct tcaaatcacg
     3241 aatgacctga gctggatcat ctgaattagt tgaaaaacta gtttctggcg cgttatagtt
     3301 ttgtggatca taaccccagt tgtaggttac atttccatcc tcatcgtatt ctttatgacg
     3361 gtctgcaatt ggttgcaatt gaacataatt gtagcccagc ttcttgatgt aatcaaaagc
     3421 agttgactgg ccgtattggt taactgttcc agcctgagca gcacccaaga aagttcctcg
     3481 aagatgttca tctacacccg atgtaggtga tttagtcaaa tcacgaatgt gcatttcaca
     3541 gataactgcc ttacatggat tttccaagcg ccaagtagcc tccgaaccgt gcttaacctc
     3601 gaagttttca acttgctttt ctacatggct cagaatagct gaacgtttgc catcagggct
     3661 ggtcgcgatt gtataaggat cacgtgtcag tgtttggtga tgagggaatt ggacttgata
     3721 ctgataagtc ttacctacca aatcttcttc aacatccaaa ctccagacac cgattgtatt
     3781 gtccttatga ttataagagt agctattgcc tcttttcatc tcaaaagtct tccaaacggg
     3841 tgcatcatta gcagctgatt cataaacgac aacttgtact tctgtcgctg taggtgacca
     3901 gagggaaaaa tgagcctgat tgtcctctac acggcaaccc aattctcctt ggtaacccca
     3961 atgatgatca aaactagcac tgttaatggc cttatcaaag gcaaaaggat tttgattttt
     4021 atagaaaggg ctggcaatag caggattttc agagtaataa atcctatcat cgccttccaa
     4081 aatccagacc tctgttaata ggggatagtg attaaaacgg atagaatatt ctttactagt
     4141 ttgacctgta tgaaccacaa aattcaagct ttctataaca tgtgaacttg ggtgttcaaa
     4201 gctaaataaa gctccaaaat aatcttcttt gtaggttagc aaatcaattc gttgatcctg
     4261 actttttaca aaggagcaag tgtcatattc tccattctta cgatggtaat gaatgcgcat
     4321 agggtagtta tacatttttt atttttcctt tttactttgt ttctatttca ctaataaatt
     4381 tttgtcaatc tcgtctcaat taacagacat agtcatattc tctaaactct gtttttaaac
     4441 gatccattac aaactttcta gccatgcctc atctctgacc tggataccaa gttcttgtgc
     4501 tttttgcagt ttacttccag cgtctgcacc taccacgacg aggtcggtct ttttagaaac
     4561 actacctgtc actttggcac ccagactttc gagtttactt ttagcttctg agcgcttgag
     4621 tcgttccaat tttcctgtca ataccacggt caaacctgac aaggccgcat ccgctactac
     4681 cgtctgtcct ttatagtcca gattgacccc agtttctttc aattctctga gcagaatttc
     4741 agatccttct gtcgcaaaat aagtctgaag acttttggca atcacgccac ctagactttc
     4801 aatactggcc acttcctctg aatctgcctg atacagattt tcaattgaat gaaaatattg
     4861 aagtaaaagc tgactagcct tgcttccgac atgacgaatt cccaaaccaa ataagagctt
     4921 ctcggcagaa ttttcctttg atgcttggat agcctgatac agtttagcag cggacttttc
     4981 cttaaccccc tctaaaagga ggaaatcctc ttcttgcaaa cgataaatat ccgccacatc
     5041 cttgactaaa ttagcagcaa aaagcttctc aacaatagat ggaccaaggc ctgtaatatt
     5101 catagcatca cgagaagcaa agtgaatcaa gccttccatg atttgagcag ggcaacgcgg
     5161 attgatacaa cgtagggcca cttcatcttc aaagtgcaac aagtcagagt tacaacttgg
     5221 acagtttgta gggatatcta gtttttcttc agaaacccgt ttggactcta ccacacgtaa
     5281 aacggcaggg atgatgtcac cagccttata tacaatgacc gtatcgtctt ttcggatatc
     5341 tttttcagca atataatcta cattgtgcag ggtcgcacgg ctaacagtcg taccggcaag
     5401 ttgtactggt gttagattag cagttggagt tacaacaccg gtacggccaa ctgtccagtc
     5461 aactgataag agttgagctt ctttttcttc ggcagggaac ttgtaggcta ctgcccactt
     5521 tggagcctta actgtaaaac caagttcttc ttgacttgct aggtcgttga ccttgattac
     5581 cactccatca atatcgtaag gcagattttc ccgttcctgt cctacttctt ggataaaatt
     5641 ccagatttca tctatgtttt cagccaagat tcgcttagga ttgaccacaa aacctagttg
     5701 ttctaggtac ttcaaaccct tttcttggct atcacgagtt gaagggctgg cttcttgata
     5761 gagaaacgtt gcaagattac gcttggcaac tactgctgta tccaactgac gcagagttcc
     5821 tgctgccgca ttacgaggat tagcaaattc aggctctcca ttttcttggc gcgcttggtt
     5881 aacttggtca aaggaagcgc gtggcatgta acattcccca cgaactgtga tatctagttc
     5941 ttctggcaaa gtcaaaggga tgtccttaac acgcttgagg ttttctgtga tattttcacc
     6001 aattgaacca tctccacgtg ttaccccagc aaccaaaatc cccttttcat aagtcagcga
     6061 gatagataag ccatcgattt tcagctcaca aatataggtc ggatgagcca cttccttacg
     6121 aacacgcgca tcaaaagcat ctagctcctc acgtgaaaaa gcatcctgca aactataaag
     6181 aggatactga tgactgtatt tttcaaaacc atctaaaacc ttgccaccaa cacgatgagt
     6241 cggactgtct gctagcactt gctctggata agcagtttct aactcgacca actcacggta
     6301 aaggcggtca tactcactgt ctgaaaccga gggattatcg ctggtatagt actcagtcgc
     6361 atagcgattg agcaaagcga ctaactcatt cattctttta ttcataagac cattttacca
     6421 taaaacaagc cctcctcaca aacgagaagg gcggaaaaaa cacttagttt gaaattattt
     6481 ttgaaactca agcaacctta tatcaatttt tcaaaatgag ttcgaacata aataaacgat
     6541 atacaagaca agatgataac accacttcca attatcagga aagaagagag atgtacactt
     6601 ggcaagactg tcataaatcc ttttgcaata ggcataaata gaatagctaa ggtaaaaatt
     6661 gtactcagta ctctcccaag aaattcgctc tcaaccttgg tttgtacttg agtaaaaaag
     6721 tgaatattaa aaatcgtcat aaacaattca caaactaaat ttccagaaaa ggaaagaaaa
     6781 gttggaagtg gtaatcccat cataaaaact ccgacacctg tcaaagccag taaaatcaaa
     6841 agattataaa tattagcttt aattttacta gctagaagag ccccaatgat ggaaccaata
     6901 gcccccatag ttaaaatact tgcataggct ccttctgacc cgtaaagctg attcgaaaag
     6961 ggaagtagaa attcaaaagc tgcaaaaaag aaattaacgc tggaagctac cagcaaaagg
     7021 aagaaaattt cttgctgatg ccagatatag tgtaacccat ccttgatatc tacaaaaata
     7081 tctctcccag taaaagcctt tttctcttga acttttgctt cctcttttgg aaggaaagcc
     7141 actagaacaa aagcaatgaa aaaaggcagc gagtctagca gtagcgtcat atggagactt
     7201 gcaaactgta aaacaaggaa ggaaagaaca ggagagctaa cacctacaac ctgcaaaacc
     7261 agctctaagc gagaattata gatcacaatc tcatctttct ccaccacttc agttatgata
     7321 gctttattgg ctgtgcgaga aaaggcaaaa gcaatagcct gcacaatgtt agcaacaatc
     7381 aaagcgccaa tcatccagct atcattcctt atgaaagaaa tagccagaca aagaatccca
     7441 caaacaagat ctgccgtcat taaaatctta cgacgagaaa aacggtctga aataactccg
     7501 ccaaagggat tgacgagaat agatgtgacg agctcagaaa tctgatacat tcctaaaact
     7561 gtctgtccta tagtccccat agaagccaac cagacactat ttccataatc atagagcata
     7621 tttcccattt tattgatagc cccacggcta atcaactgca ctgcatagcg attcatatta
     7681 aagctcctct caaattttga aactattgta tcaaaaccga aaggagcttt ttattttttc
     7741 ccttatttgg gaaaattaac ttttgacaaa tttttcgtag tgttcctgat aataggctac
     7801 ttgctctgga agacctaaca catcaaaaat atgtatggcc tcttgcatct gcttacagcc
     7861 ttctttacac tgtccttttt gatataaggc aaaacctttt aaataatgga aaacattacg
     7921 ctcataaagc ttaatatctt tgtcaataat cttctctgta taagcctcaa aatagttggc
     7981 attataaaaa gaagaatgct ctaaacaatg ctggtaacaa ttgagggcca aaattaacac
     8041 taatctctta tggcgactaa tctcttggta aaattcctcc ctctccataa cttctctacc
     8101 aatccgagtg acatagtcta catcgtagaa actatagagg ttaccgaaaa gaatcaactc
     8161 atacatggtc cattcttctg ttttgaagag ataatctgct accttatcca aatcatcctg
     8221 cttcatatca taagtcgcat ctctttgaca aatcagacct tgtagcaaaa tccagttcag
     8281 ctcaaaataa aggggagtcg tcgaactctt agacttttca agttgttctc tttgaagctt
     8341 ttgaaaacct gcaatatcgt ttgaatagta aagtgggata atctgtgcca tcatagacac
     8401 atgttcatga ttatgaaaat tccttgcctt atccatgaaa ttttcgattg ttacatgaat
     8461 gttatccaaa atctcaaaga aacgggagac tgccaggtca gactccccaa gctcaaagcg
     8521 agataactga gaggtagagc aggattcgcc tgctgcttcc tttaaagaat aatttccact
     8581 tgttcgaaat tcacgaaata cttttccaag atgttccatt tttacacctg ctctgataat
     8641 tcttcccact caagcatagc ttcttcctga cgatggctga ttttgtccag ctcagcctgt
     8701 aattccatga gtttgtcggc atcgtttgtt tccaacattt gttcagaaat ggcttggctt
     8761 tgactttcta gctcttcaat ttcagcttct agactttcga tttgtcgcat gagtttgcga
     8821 acttcttttt gactttcttt ctgggcctga tagtcattga ctggacttgc ttcctttgct
     8881 tgattgctag ttgaagcttc ctcagtctga ctcatttctg ctgttgctct cttctcaata
     8941 tagtagtcgt aatctccaag gtagagagtt gaaccattct cagacaattc caaaacatga
     9001 gttgccacac gattgataaa gtaacgatca tgactgacaa acagcaaggt tccatcaaag
     9061 tcaatcaagg cattttctag cacttcctta ctatcaatat ccaagtggtt ggtcggctca
     9121 tccagaatca aaaaattatt gttttccata gacaatttag ctaaaagcaa acgagctttt
     9181 tcgccaccag atagcatgcc gactgatttt ttaacatcat ctcctgagaa aaggaaggct
     9241 ccaagacggt tgcggatttc aacttctggt gtcagtttga aatcattcca gagttcatcc
     9301 agcaccgtat tacttggtgt cagcttgctt tgggtttggt catagtaacc aacctcaaca
     9361 ttagcgccaa agcgcttttc tcccttgata aaaggaatct ggtccacaat agacttgata
     9421 aaggttgact tgccgatacc atttggacca acgatagcga cagcattcat cttacgaaga
     9481 tctaggttga taggttgtga caagacttcc ccgtcataac caatagcagt attttcaaca
     9541 gtcaaaacaa cattgcccga cgttttttca gactggaagg tcatgttggc tgctttcttg
     9601 ccagcttcag gcttgtccaa acgctccatt ttttctagtt gtttacggcg agattgagca
     9661 cgtttagtcg ttgaagcacg aactagattg cgattgacaa agtcttccag agcagcgatt
     9721 tccttctgtt gcttttcata gttttttgcc tcagtaacta gcttttgctc cttcaattcg
     9781 acaaaacgag agtaattccc cacatagcga tccaaggaat gcttggtcaa atctagcgta
     9841 attgtcgcaa ccttgtccaa gaaataacgg tcgtggctga cgataaggag ggcaccgcta
     9901 tagtttacca agtaattctc tagccaggcg atggtttcaa tatccaagtg gttagttggc
     9961 tcgtccaaga ccaagagatt gggcttttca aggagcattt tggcaagtgc caaacgagta
    10021 ttttgaccac cagaaagctc agcaattttc atctgccaca tagactcgtc aaacttgaat
    10081 ccattcaaaa tcgctcgaat atcagcttca taggtaaagc cacctgcttg gcgaaaattc
    10141 tcagataagc ggtcataatc tgacatcagt ttatccaaat cctcaccaga cttttcaccc
    10201 atctccagct ccatctgacg cagttgtctc tccgtccgac gcaaattatt aaagacatga
    10261 agcatttcat cgtagatggt attttcagac tcaaaacggc tatcttgggc taggtaagac
    10321 agagaaatat cttttttctt attgatttct ccgctagttg gctcctcttc tccaactaaa
    10381 atcttcaaaa gagtagactt acctgcacca tttttcccaa caagggcaat ccgatctcgt
    10441 tcatcaacct gcaggttgat attatcgaaa agaacctctc ctgcaaaaga acgttcaatt
    10501 ttattagctt gtaaaataat cataagagta gtatagcatg tttccctaag gcattcaaga
    10561 taatcgtaag tcttttagta caacttttat aacataaaat aaactaaatt atgtatattt
    10621 tatattagat tcttcactat cttgttggat tttctaacca gctaatcttg tttcaaatag
    10681 ttatcgcaca agcctattat ttaattcttt tcattattta cgtac
//
LOCUS       DBEJAU010000057        10722 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC323 isolate 683620
            SAMN38261939-rid24807223.denovo.057, whole genome shotgun sequence.
ACCESSION   DBEJAU010000057 DBEJAU010000000
VERSION     DBEJAU010000057.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261939
            Sequence Read Archive: SRR26833919
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 10722)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10722)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576303.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576303.1
            Genome Coverage       :: 154x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/19/2025 01:05:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,121
            CDSs (total)                      :: 2,078
            Genes (coding)                    :: 1,943
            CDSs (with protein)               :: 1,943
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 36
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 72 of 135
            Pseudo Genes (incomplete)         :: 63 of 135
            Pseudo Genes (internal stop)      :: 51 of 135
            Pseudo Genes (multiple problems)  :: 46 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10722
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261939-rid24807223.denovo.057"
                     /strain="GPSC323"
                     /isolate="683620"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            <1..253
                     /locus_tag="ACL29Z_001789"
     CDS             <1..253
                     /locus_tag="ACL29Z_001789"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=2
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0070053.1"
                     /translation="LYSMKIKEQTRKLAAGCSKHCFKVVDGTDEVSSKHRFEVVDRTD
                     EVSSKHRFEVVDRTDEVSSKHRFEVVDRTDEVSNIYTAR"
     gene            complement(276..1229)
                     /locus_tag="ACL29Z_001790"
     CDS             complement(276..1229)
                     /locus_tag="ACL29Z_001790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000028179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aromatic acid exporter family protein"
                     /protein_id="HGR0070054.1"
                     /translation="MSISQRTTKLILATCLACLLAYFLNLSSAVSAGIIALLSLSDTR
                     RSTLKLARNRLFSMLLALAIGVLAFHLSGFHIWSLGLYLAFYVPLAYKMGWEIGITPS
                     TVLVSHLLVQESTSPDLLVNEFLLFAIGTGFALLVNLYMPSREEEIQHYHTLVEEKLK
                     DILQRFKYYLSRGDGRNRAQLVAELDTLLKEALRLVYLDHSDHLFHQTDYHIHYFEMR
                     QRQSRILRNMAQQINTCHLAASESLILAQLFSKIAGQLSQTNPASDLLDEIERYLEVF
                     RNRSLPKTREEFETRATLLQLLREAKTFIQVKVDFYQKYRQ"
     gene            complement(1297..2506)
                     /gene="sstT"
                     /locus_tag="ACL29Z_001791"
                     /pseudo
     CDS             complement(1297..2506)
                     /gene="sstT"
                     /locus_tag="ACL29Z_001791"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000713440.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015293 - symporter activity [Evidence
                     IEA];
                     GO_process: GO:0015826 - threonine transport [Evidence
                     IEA];
                     GO_process: GO:0032329 - serine transport [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="serine/threonine transporter SstT"
     gene            2645..3205
                     /locus_tag="ACL29Z_001792"
     CDS             2645..3205
                     /locus_tag="ACL29Z_001792"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="mechanosensitive ion channel domain-containing
                     protein"
                     /protein_id="HGR0070055.1"
                     /translation="MQKFIQAYIEKLDVTTIIENILTKVISLLLLLIVFYIAKKMLHT
                     MVQRIVKPSLKMSRHDVGRQKTISRLLENVFNYTLYFFLLYCILSILGLPVSSLLAGA
                     GIAGVAIGMGAQGFLSDVINGFFILFERQLDVGDEVVLTNGPITVSGKVVSVGIRTTQ
                     LRSEEQALHFVPNRNITVVSNFSRTD"
     gene            3262..4170
                     /locus_tag="ACL29Z_001793"
     CDS             3262..4170
                     /locus_tag="ACL29Z_001793"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000242243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046873 - metal ion transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0030001 - metal ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium transporter CorA family protein"
                     /protein_id="HGR0070056.1"
                     /translation="MVLEKQLGNGCTWIDLDLGKLNKLEDLSEIYGLDKETIEYALDR
                     NERAHMDYHRESETVTFIYNVLDVKKDKAYYETFPMTFIVEHRRLITISNTKNAYVIE
                     QMTRYLENHDTLSIYKFLFASLEIISNAYYPVIEQMDKSRDEVNDLLRQRTTKKNLFV
                     LSDLETGMVYLTAAAKQNRILLEHIQGHALYRSFDEIEREQFDDAMIEAHQLVSMTDL
                     ISQILQQLSASYNNILNNNLNDNLTTLTIISVLLAVLAVVTGFFGMNVPLPLTDEPHA
                     WLYISLASAGLWIVLSLLLRKIAKKS"
     gene            4185..4712
                     /locus_tag="ACL29Z_001794"
     CDS             4185..4712
                     /locus_tag="ACL29Z_001794"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004251415.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008962 - phosphatidylglycerophosphatase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YqeG family HAD IIIA-type phosphatase"
                     /protein_id="HGR0070057.1"
                     /translation="MAIENYIPDFAVEAVYDLTVPSLQAQGIKAVLVDLDNTLIAWNN
                     PDGTPEMKQWLHDLRDAGIGIIVVSNNTKKRVQRAVEKFGIDYVYWALKPFTFGIDRA
                     MKEFHYDKKEVVMVGDQLMTDIRAAHRAGIRSILVKPLVQHDSIKTQINRTRERRVMR
                     KITEKYGPITYKKGI"
     gene            4715..5821
                     /gene="yqeH"
                     /locus_tag="ACL29Z_001795"
     CDS             4715..5821
                     /gene="yqeH"
                     /locus_tag="ACL29Z_001795"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000391231.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_process: GO:0042254 - ribosome biogenesis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase YqeH"
                     /protein_id="HGR0070058.1"
                     /translation="MEEILCIGCGATIQTTDKAGLGFTPQSALEKGLETGEVYCQRCF
                     RLRHYNEITDVQLTNDDFLKLLHEVGDSDALVVNVIDIFDFNGSVIPGLPRFVSGNDV
                     LLVGNKKDILPKSVKSGKISQWLMKRAHEEGLRPVDVVLTSAQNKHAIKEVIDKIEHY
                     RKGRDVYVVGVTNVGKSTLINAIIQEITGDQNVITTSRFPGTTLDKIEIPLDDGSYIY
                     DTPGIIHRHQMAHYLTAKNLKYVSPKKEIKPKTYQLNPEQTLFLGGLGRFDFIAGEKQ
                     GFTAFFDNELKLHRSKLEGASAFYDKHLGTLLTPPNSKEKEDFPRLVQHVFTIKDKTD
                     LVISGLGWIRVTGIAKVAVWAPEGVAVVTRKAII"
     gene            6035..6346
                     /gene="yhbY"
                     /locus_tag="ACL29Z_001796"
     CDS             6035..6346
                     /gene="yhbY"
                     /locus_tag="ACL29Z_001796"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000060164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome assembly RNA-binding protein YhbY"
                     /protein_id="HGR0070059.1"
                     /translation="MSLTSKQRAFLNSQAHTLKPIIQIGKNGLNDQIKTSVRQALDAR
                     ELIKVTLLQNTDENIHEVAEILEEEIGVDTVQKIGRILILFKQSSKKENRKISKKVKE
                     I"
     gene            6398..7027
                     /locus_tag="ACL29Z_001797"
     CDS             6398..7027
                     /locus_tag="ACL29Z_001797"
                     /EC_number="2.7.7.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000151307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016779 - nucleotidyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0009435 - NAD biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinate-nucleotide adenylyltransferase"
                     /protein_id="HGR0070060.1"
                     /translation="MTIELLTPFTKVELEPEIKEKKRKQVGILGGNFNPVHNAHLIVA
                     DQVRQQLGLDQVLLMPEYQPPHVDKKETIPEHHRLKMLELAIEGIDGLVIETIELERK
                     GISYTYDTMKILTEKNPDTDYYFIIGADMVDYLPKWYRIDELVDMVQFVGVQRPRYKV
                     GTSYPVIWVDVPLMDISSSMVRDFLAQGRKPNFLLPQPVLDYIEKEGLY"
     gene            7027..7620
                     /gene="yqeK"
                     /locus_tag="ACL29Z_001798"
     CDS             7027..7620
                     /gene="yqeK"
                     /locus_tag="ACL29Z_001798"
                     /EC_number="3.6.1.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000331212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bis(5'-nucleosyl)-tetraphosphatase (symmetrical)
                     YqeK"
                     /protein_id="HGR0070061.1"
                     /translation="MSYQDYINCSREALLEKMAELLPEKRLTHCLGVERAAMELAQRF
                     GVDVEKASLAGLLHDYAKKLSDQEFLVLIDRYQLDPDLKNWGNNVWHGMVGIYKIQED
                     LDLHDSEILRAIEIHTVGAGQMTDLDKVIYVADYIEHNRAFPGVDVAREIASLSLNKA
                     VAYETARTVEYLAHQGFPIYPQTLETYNAFVHYLKED"
     gene            7621..8121
                     /locus_tag="ACL29Z_001799"
     CDS             7621..8121
                     /locus_tag="ACL29Z_001799"
                     /EC_number="3.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000844697.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase family protein"
                     /protein_id="HGR0070062.1"
                     /translation="MKTAFIIIDVQNVLVETGFQTKSLLEKISYLQNQARSKNIEIIY
                     VQHIENSEAQTSEDWQLSALLNRKPAEKVFQKKYNSIFKETGLKEYLDKQGIEKLVLC
                     GMQTEYCVDTSVKVAFEYGYQLIVPEGAVTTFDGDDIPAETINEFYEDIWEERFADVL
                     DYKHIF"
     gene            8134..8487
                     /gene="rsfS"
                     /locus_tag="ACL29Z_001800"
     CDS             8134..8487
                     /gene="rsfS"
                     /locus_tag="ACL29Z_001800"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001003018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0043022 - ribosome binding [Evidence IEA];
                     GO_process: GO:0017148 - negative regulation of
                     translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome silencing factor"
                     /protein_id="HGR0070063.1"
                     /translation="MNEKELLELVVKAADEKRAEDILALDVQDLTSVTDYLVITSSMN
                     SRQLDAIAANIREKVAQAGFKGSHVEGDAAGGWVLLDLGAVVVHIFSEEMRAHYNLEK
                     LWHEANSVDISEALA"
     gene            8806..9546
                     /locus_tag="ACL29Z_001801"
     CDS             8806..9546
                     /locus_tag="ACL29Z_001801"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000257057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HGR0070064.1"
                     /translation="MATYETFAAVYDAVMDDSLYDKWTNFSLRHLPKTKERKKLLELA
                     CGTGIQSVRFSQAGFDVTGLDLSADMLKIAEKRATSAKQKIAFIEGNMLNLSKAGKYD
                     FVTCYSDSICYMQDEVEVGDVFKDVYNALNEEGVFIFDVHSTYQTDEVFPGYSYHENA
                     EDFAMLWDTYEDEVPHSIVHELTFFIKEADGSFSRHDEVHEERTYEILTYDILLEQAG
                     FKSFKLYADFEDKEPTETSTRWFFVAQK"
     gene            9556..10653
                     /locus_tag="ACL29Z_001802"
     CDS             9556..10653
                     /locus_tag="ACL29Z_001802"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000156376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyltransferase"
                     /protein_id="HGR0070065.1"
                     /translation="MTITGIIAEFNPFHNGHKYLLDQAEGLKIVAMSGNFMQRGEPAI
                     VDKWTRTQMALENGADLVVELPFLVSVQAADFFGQGAMDILDRLGIDSLVFGTEEVRD
                     YQKIADLYTEKGAEMEKFVENLPDSLSYPQKTQAMWKEFAGLDFSGNTPNHVLALAYA
                     KAVAGRNIKLHPIQRQGAGYHSVNKDVDFASATALRQHQKDQDFLERFMPSVALFEQA
                     SKVIWEDYFPLLRYQILSNPDLTTIYQVNQEMAVRIKEAIKTAQSVEELVELVTTKRY
                     TKARVRRLLTYILMQARESDLPEAIHVLGFTEKGRQHLKSLKGQVSLVSRIGKEPWDA
                     MTQKADQIYQLGKPSIAEQNFGRVPIRIETN"
BASE COUNT         3245 a         2084 c         2491 g         2902 t
ORIGIN      
        1 tttatactca atgaaaatca aagagcaaac taggaagcta gccgcaggct gctcaaaaca
       61 ctgttttaag gttgtggatg gaactgacga agtcagctca aaacaccgtt ttgaagttgt
      121 agatagaact gacgaagtca gctcaaaaca ccgttttgag gttgtggata gaactgacga
      181 agtcagctca aaacaccgtt ttgaggttgt ggatagaact gacgaagtca gtaacatata
      241 tacagcaagg tgaagctgac gtagtttgaa gagtattact gtctatattt ttggtaaaaa
      301 tcaactttta cttggatgaa ggttttggct tcacgtagga gttgaagaag ggtggcgcgg
      361 gtttcaaatt cttctcttgt cttgggcaga ctgcggttcc ggaagacttc cagataacgt
      421 tcaatttcat ctagcaaatc agaagcagga ttggtctggc tcagttgacc tgcaattttt
      481 gaaaagagtt gcgctaagat caggctttca ctggcggcaa ggtgacaagt gttaatctgt
      541 tgggccatgt ttctcaggat acgactttgt cgttgtctca tctcaaagta gtggatatgg
      601 tagtcggtct ggtgaaagag gtggtcagag tgatccaaat agaccagtct gagggcttct
      661 ttcaaaagcg tgtctaattc tgctaccagc tgtgctcggt tgcgtccgtc tcctctggat
      721 aaatagtatt tgaagcgctg gaggatatct tttaactttt cttccaccag cgtgtggtag
      781 tgctggattt cctcttctcg tgaaggcata tagagattaa caagcaaggc aaatcctgta
      841 ccaatagcaa agagaaggaa ttcattgact agaaggtctg gagaggttga ctcttgaacc
      901 aagagatggc taaccaaaac agtgcttggt gtgatgccaa tttcccagcc catcttgtag
      961 gctaaaggaa cgtagaaggc cagatagagg ccgagactcc agatatgaaa tccgctcaag
     1021 tgaaaagcta gaacaccgat agccagagct agaagcatag aaaaaagacg attgcgagcc
     1081 agttttaaag tacttctacg cgtatcagat aggctcaaga gagcgataat tccagccgaa
     1141 actgctgacg aaagattgag aaaataagca agcaggcagg caagacaggt agctaagatg
     1201 agcttggtcg tacgttggct aatagacata agaatttcct aataagttag aataaaagcg
     1261 taaaagacaa gacatgagca ggcttgcctt gatgagttat tttttacggg ttgctgcgta
     1321 ttcggcaacg gcggtaaaga ggacatctgt agaagagtta agggctgttt cacatgagtc
     1381 ttggatgaca ccaatcacaa aaccaacccc aacaacttgt atggcaatat cgttagaaat
     1441 accgaaaagg ctacaagcaa ctgggataag aaggagggaa cctccggcaa tacctgaagc
     1501 accacaggct gagatagctg ctaccacact gaggacaaag gctgtggcaa agtcaacagg
     1561 aattccaaga gtgttaactg cagcaagggt caaaaggtta atggtaatcg ctactccagc
     1621 catattgata gtagaaccga gtgggataga aacagaatag gtatctgggt tgagtccaag
     1681 gtcatggcag agtttcatgt tgacaggaat gttagtcgca gaactacgag tgaaaaaggc
     1741 tgtcacaccg ctgacacgga ggcagttcca aactagaggg taaggattgc gtctcataaa
     1801 gaagaaggca atcaaagggt tgaccacagg ggcaacaaaa agcatagtcg ttactaatag
     1861 aaccaataaa ataccgtagt tggcaaggct tccgactccc ttgtcagaaa tggttttaaa
     1921 aacaagacca aggattccaa atggagccag attgatgatc cattcgacaa ttttagaagt
     1981 cacgtcagcg atagttttta gcaattcttg actattttta ctggcttctc tcatagcgat
     2041 tccaaaaatg actgcccaag ataagattct aatatagtta gcagtaagca gggcgttgac
     2101 tgggttgtca accagtttga gcaagaggtt gctgagaacc tgcccaatcc catctggtgg
     2161 tgcaatttca gtattggcac tatttggggt aatttcaata gggacgatga aatttgctag
     2221 tacagctaca agagcagcgg cgaaagtccc tatcatagga tatacaagaa aacaacagtt
     2281 ttcatattgc tatcttgtcc cttttgatgt tgggaaaggg cattggcaac gagagcaaag
     2341 actaggatag gagcaacagc ttttagacct ccaacgaata aatcctcgag tagcccaatc
     2401 cctgagagat taggaagggt cagtcctagg attccccaca aagcatacca atcaagatac
     2461 gcttgacaag gcttgcctta ttccaagcat gaatgattct tttcataata atctcctttt
     2521 tgtgtagtga ttatgattat agtataaatg atagacaaaa tcaagaattt tctgtctatt
     2581 ttttgaatat ttatggagaa tgagactgat gaaaatatgg tataatgaaa taaaggagtt
     2641 ttatatgcaa aaatttattc aggcttatat tgaaaagcta gatgtgacaa ccattatcga
     2701 gaatattcta accaaggtca tttctctttt actgctttta attgtatttt atattgctaa
     2761 aaaaatgctt cataccatgg tgcagagaat tgtcaaacct tctctaaaaa tgtctcgtca
     2821 tgatgttgga cgccaaaaaa ccatctcacg tttactagaa aatgtgttta attatacgct
     2881 atatttcttt ttactctact gcattttgtc gattttaggt ttgccagttt ctagtttgct
     2941 ggctggagct ggtattgctg gggtagcgat tggtatggga gcccaaggct ttctgtctga
     3001 tgtcatcaat ggctttttca tcctctttga acgtcaactg gatgtgggag atgaggtcgt
     3061 tctgacaaat ggaccgatta ctgtatcggg taaggttgtc agtgtgggaa ttcgtacgac
     3121 acagcttcgt agcgaggagc aagcccttca ctttgtccct aaccgaaata tcacagttgt
     3181 tagcaatttc tcacgcacag actagacctg ttattttaag taatttgtgg tacaatagag
     3241 ggagtttaat aaggagaaaa gatggtttta gaaaagcagt tgggcaatgg ttgtacctgg
     3301 atagacctag acctaggaaa gttgaataaa ctagaagacc tttctgaaat ttacggtttg
     3361 gacaaggaaa ccattgaata cgcactggat agaaacgagc gcgcccacat ggactaccac
     3421 cgtgaaagtg agacggttac ctttatctat aatgtcttag acgtaaaaaa ggacaaggcc
     3481 tactatgaga cttttcccat gacctttatt gtcgagcatc gtcgcctgat taccattagt
     3541 aataccaaga acgcctatgt cattgaacag atgactcgtt atctggagaa ccatgacacg
     3601 ctttcgattt ataagtttct ctttgccagt ctggaaatca tcagcaatgc ctactatcct
     3661 gtcattgagc agatggacaa gagtagggat gaggtcaatg acctcttgcg ccagcgaact
     3721 accaagaaaa acctctttgt cctgtctgat ttggagactg gtatggttta tctgacggca
     3781 gctgccaaac aaaatcggat tttgttagag catattcaag gtcatgcctt gtatcgtagt
     3841 tttgatgaga ttgagagaga acagtttgat gatgccatga ttgaggctca tcagctggta
     3901 tccatgacag acctaatctc tcagatttta cagcagcttt cagcctctta caacaatatt
     3961 ctaaacaata atctgaatga caatttgaca accttgacta tcatttcagt cttgctagct
     4021 gttttggcag tcgtgacagg ctttttcgga atgaatgttc ccttaccttt aacagatgag
     4081 ccccatgctt ggctctatat cagtttggct agtgcaggtt tgtggattgt tttatccttg
     4141 ttactaagga aaattgcgaa aaaaagttaa gaaaaggagc cagaatggcg attgaaaatt
     4201 atataccaga ttttgctgtg gaagcagtct atgatctgac agtcccaagc ctgcaggcgc
     4261 agggaataaa ggctgttttg gtcgatttgg ataataccct cattgcttgg aacaaccctg
     4321 atggaacgcc agagatgaag caatggctac atgaccttcg ggacgcgggt attggcatta
     4381 tcgtagtgtc aaataacacc aaaaaacgcg ttcaacgagc agttgagaaa tttgggattg
     4441 attacgttta ctgggccttg aagcccttca catttggtat tgaccgtgct atgaaggaat
     4501 tccactatga caaaaaggaa gtggtcatgg ttggtgacca actcatgaca gatatacgag
     4561 cagcccaccg tgcagggatt cggtcaattt tagtcaaacc cttggtccaa catgactcaa
     4621 tcaaaacgca gattaaccga actcgtgagc gtcgtgttat gagaaaaatc actgaaaagt
     4681 acggaccgat tacatataaa aaaggaattt aactatggaa gaaattctct gtattggttg
     4741 tggagcaacc attcagacga cagataaagc tggtcttggt tttacccccc agtcggcact
     4801 tgaaaaaggt ttggagactg gcgaagtcta ttgccaacgc tgtttccgtc tccgccacta
     4861 caatgaaatc acagatgtcc agttgacgaa cgatgatttc ctcaagctct tgcacgaggt
     4921 gggagacagt gatgctttag tggtcaatgt tattgatatc tttgatttta atggatctgt
     4981 catcccaggt ttaccacgtt tcgtctcggg caatgatgtc ctcttggtag gaaataaaaa
     5041 agatatcctt cctaagtcag ttaagtctgg taagattagc cagtggctca tgaaacgtgc
     5101 ccatgaagaa ggtcttcgtc cagtcgatgt ggtcctaact tcagcacaaa ataaacatgc
     5161 cattaaggaa gtcattgaca agattgaaca ctaccgtaag ggccgcgatg tctatgtggt
     5221 cggtgtgacc aacgttggaa aatcaactct aatcaatgct attatccaag aaatcacggg
     5281 tgatcagaat gtcatcacta cttcacgctt cccagggaca accttggaca aaatagagat
     5341 tccgcttgac gacggatctt atatttacga tacgccggga attatccacc gccaccagat
     5401 ggctcactac ttgacggcca aaaacctcaa gtatgtcagt cctaaaaagg aaatcaagcc
     5461 taagacctat cagcttaatc ctgagcaaac cctattttta ggtggtttgg gacgctttga
     5521 ctttatagca ggagaaaagc aaggatttac tgctttcttt gataatgaac tcaaactcca
     5581 tcgtagcaag cttgaaggag ctagtgcttt ctacgataag cacctgggaa ctcttctgac
     5641 accaccaaat agcaaggaaa aagaagattt cccaaggcta gtccagcatg tctttaccat
     5701 taaagataag acagacctag ttatctcagg cctaggatgg attcgtgtaa caggcatagc
     5761 aaaagtcgcc gtctgggcac cagaaggcgt cgccgtcgtc acacgaaaag caattattta
     5821 aaacaaaatc gctgagcgaa caaagtgagc tcatatagcg atagttattg ctgtggtgtg
     5881 attgccaatc tgtagattgg caaggggcac aattgagacc aagactcaat tgtgaggtca
     5941 ggaaatccat ttttcaaaga tgaaatcttt ggaaaattag ttccgaccgt ccctcaccac
     6001 ctaaaataac tatcaaaaaa caaggaagaa aattatgtca ttaacatcaa aacaacgtgc
     6061 cttcctcaac agccaggcac acaccctcaa acctatcatc caaatcggga aaaatggact
     6121 caacgaccaa atcaaaacca gcgtccgtca agctcttgat gcgcgtgaat taatcaaggt
     6181 tactctctta caaaacacag atgaaaacat ccacgaagta gctgaaattt tggaagaaga
     6241 aatcggtgtg gatacagtcc aaaaaatagg acgcatcttg attttgttta aacaatctag
     6301 caagaaagaa aatcgcaaga tttctaagaa agtcaaagaa atctaagacc gaaactccaa
     6361 ataactgttt ttatagagaa ataaagggga ctagcctatg acaatcgaac tattgactcc
     6421 ctttaccaag gtagagttgg agccagaaat caaggagaaa aaacgcaaac aagttgggat
     6481 tttagggggg aattttaacc ctgttcacaa tgcccatctc attgttgcgg atcaagtacg
     6541 gcaacagttg ggactggatc aagttcttct catgcctgaa taccaacctc ctcacgttga
     6601 taaaaaggaa accatccctg aacaccatcg tctcaagatg cttgagttgg caattgaggg
     6661 aattgacggc ctagtcattg aaaccattga gttggagcgc aagggtattt cctacaccta
     6721 cgacaccatg aagattttga cagagaagaa tccagatacg gattattact ttatcatcgg
     6781 tgccgacatg gttgactatc tgcctaagtg gtaccgaatt gatgaactgg ttgacatggt
     6841 tcagtttgtg ggggttcagc gtccacgcta caaggtaggg acttcctatc cagttatctg
     6901 ggtggacgta ccgctcatgg atatctcgtc cagcatggtg cgggacttcc ttgcccaagg
     6961 tcggaaaccc aactttctcc tacctcagcc agtgctagac tacatcgaga aggaagggct
     7021 ctactgatgt cctatcaaga ctatatcaac tgctcccgtg aggccttgtt ggaaaaaatg
     7081 gcagagcttc tacctgagaa acgtctaacc cattgtctag gtgtggagcg tgccgctatg
     7141 gaattagctc agcgctttgg tgtagatgtt gagaaagcaa gtctagcagg tcttcttcat
     7201 gactatgcta aaaagttgtc agatcaggaa tttctagtct tgattgaccg ttaccagcta
     7261 gaccctgacc tcaaaaactg gggcaataat gtctggcatg gtatggtcgg aatttacaaa
     7321 attcaggaag atttggattt gcatgattct gaaattctgc gagccattga aattcataca
     7381 gtcggagctg gtcaaatgac agacctagat aaggtcatct acgtcgcaga ctatatcgag
     7441 cacaatcgag cctttcctgg agtagatgtg gcgcgtgaga ttgcaagtct atcgctcaat
     7501 aaggcggtgg cctacgaaac agctcgtacc gtggagtatc tagctcatca gggattcccc
     7561 atctatcccc aaacccttga aacctataac gcctttgtgc actatttgaa agaggactaa
     7621 atgaagacgg cttttataat cattgatgtt cagaatgttt tagtagaaac tgggttccag
     7681 acaaaaagtc tattggaaaa aatttcttat ttacaaaacc aggctagaag caagaatatt
     7741 gaaattatct atgttcaaca tattgagaac tctgaagctc aaacatcaga agattggcag
     7801 ttatctgcgc ttttaaatcg aaaacctgct gaaaaggtct ttcagaagaa gtataacagt
     7861 attttcaaag aaactggctt aaaagaatac ttggataagc aggggattga aaaattagtt
     7921 ttatgtggta tgcagacaga atattgtgtg gatacctctg tcaaggttgc ctttgaatat
     7981 ggctatcagc ttattgttcc agaaggtgct gtcacaacct ttgatgggga tgacattcca
     8041 gcagaaacga ttaatgaatt ttatgaggac atttgggagg agcgctttgc agatgttcta
     8101 gattacaaac atattttcta aaaagaggat taaatgaacg aaaaagaatt actagaacta
     8161 gtcgtgaaag cggctgatga gaaacgtgcg gaggatatcc tcgcacttga tgtacaagat
     8221 ttgactagtg tgacggacta cttggtcatc actagctcaa tgaatagccg tcagttggac
     8281 gctatcgcag ctaatatccg tgaaaaagta gctcaagcag gctttaaagg tagccatgtc
     8341 gaaggcgatg cagctggagg ctgggtctta ctggacctcg gtgctgttgt cgtgcatatc
     8401 ttttcagaag aaatgcgtgc ccattataat ctagagaagc tatggcatga ggcgaattca
     8461 gtagatattt cagaagctct tgcttagaag atgaactcag ttgtagtcaa ctgggtttct
     8521 ttgcttattt tagaaaaatt gatagaaagg taaagggcta gtgtttgttt catttcgaaa
     8581 ctgaacacga gctaaaagct gagataaaaa gtaactttct ttgtatctga cgatagggaa
     8641 gaaagtttcc tatgtactct ttgcttttaa ggctctttgt atcttagaaa ggatttgaac
     8701 ccgtcctgta attctcggaa aatagatagc cttccttgga gctcggctcc atcgtaaggc
     8761 tcctaatttt ctatcgaatt acgggcggac ttggtatcat gttttatggc gacttatgaa
     8821 acctttgcgg cggtctatga tgcggtcatg gacgatagtt tatacgacaa atggacgaat
     8881 ttttctctgc gtcatttgcc taagaccaag gagagaaaga aactcttgga attggcttgt
     8941 gggacaggaa ttcaatcagt gcgcttctct caggctggtt ttgatgtgac tggacttgac
     9001 ttgagtgcgg atatgttgaa gattgcggag aagagagcaa cttcagccaa gcaaaagatt
     9061 gcttttatag aaggtaatat gctgaatttg tccaaggcag ggaaatacga ttttgtcacg
     9121 tgttattcgg actctatctg ctatatgcag gatgaggtgg aagtagggga cgtctttaag
     9181 gacgtgtaca atgcgctgaa tgaagaggga gttttcatct ttgacgtgca ctcgacctac
     9241 cagacagatg aagtattccc tggctattcc taccatgaaa atgcggaaga ttttgccatg
     9301 ctttgggata catatgagga cgaagttcct cactccatcg tgcatgagct gactttcttt
     9361 atcaaggagg ctgacggttc ctttagtcgc cacgatgaag tacatgagga gaggacctat
     9421 gagatcttga cctatgatat cttgctggaa caggctggat ttaagtcctt caaactctat
     9481 gcagactttg aggataagga gccaacagaa actagcaccc gttggttttt tgtggcgcag
     9541 aagtaggaga ttagcatgac cataacaggt attatcgcgg agttcaatcc ttttcataat
     9601 ggccataaat acctgctgga tcaggcagag ggactgaaaa ttgttgccat gtcagggaat
     9661 ttcatgcagc gtggagagcc tgctattgtg gataagtgga caaggaccca gatggcgctg
     9721 gaaaatggcg cagacttggt agtggaattg ccctttttag tcagtgttca ggcagctgat
     9781 ttctttggtc aaggagctat ggatatcttg gatcgcttgg gcattgatag tctagttttt
     9841 gggacagagg aagttcgaga ttatcagaaa attgctgact tatacacaga gaaaggtgct
     9901 gagatggaga aatttgtgga aaatctgcct gattcccttt cctatcccca gaaaacccaa
     9961 gctatgtgga aggaatttgc tggtcttgat ttttcaggta atacccccaa tcatgttctt
    10021 gctctggcct atgccaaggc ggttgcagga cggaatatca agctgcatcc gattcagcgt
    10081 cagggggcag gttaccattc tgtgaataaa gatgtggact ttgcctcggc gacagccctc
    10141 cgtcaacatc agaaggacca agatttctta gaacgtttta tgccttctgt tgccctattt
    10201 gagcaggcca gtaaggtgat ctgggaagac tattttccct tgctccgcta tcaaatcttg
    10261 tcaaatcccg acctaaccac catctatcag gtcaatcaag aaatggctgt gcgcattaaa
    10321 gaagctatta aaacagccca gtctgtggaa gaattggtcg agttagtgac taccaaacgt
    10381 tacaccaagg cgcgtgtcag acgcctattg acctatattt tgatgcaggc tagagaaagt
    10441 gacttgccag aagccattca tgtccttgga tttactgaaa aaggtaggca acatctcaag
    10501 tctttgaaag gtcaggtcag tctagtcagc cgaattggca aagaaccttg ggatgctatg
    10561 acccaaaaag cagaccagat ttaccaacta gggaagccaa gtatagcaga gcaaaatttt
    10621 ggaagagtgc cgattagaat agaaacaaac taagtctacc gaaaggtagg ctttttgaga
    10681 ttttttacga ataatactct tcgaaaatca aattcaaatc gc
//
LOCUS       DBEJAU010000058        10642 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC323 isolate 683620
            SAMN38261939-rid24807223.denovo.058, whole genome shotgun sequence.
ACCESSION   DBEJAU010000058 DBEJAU010000000
VERSION     DBEJAU010000058.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261939
            Sequence Read Archive: SRR26833919
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 10642)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10642)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576303.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576303.1
            Genome Coverage       :: 154x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/19/2025 01:05:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,121
            CDSs (total)                      :: 2,078
            Genes (coding)                    :: 1,943
            CDSs (with protein)               :: 1,943
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 36
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 72 of 135
            Pseudo Genes (incomplete)         :: 63 of 135
            Pseudo Genes (internal stop)      :: 51 of 135
            Pseudo Genes (multiple problems)  :: 46 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10642
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261939-rid24807223.denovo.058"
                     /strain="GPSC323"
                     /isolate="683620"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            complement(406..1299)
                     /locus_tag="ACL29Z_001803"
     CDS             complement(406..1299)
                     /locus_tag="ACL29Z_001803"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000343891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HGR0070066.1"
                     /translation="MDELKREIGYKIKTIRRSCGKTQIDICGDESELTIRQLARIENG
                     QALATLPKLLLIADKLGVSLQNIVDVKVIEIPKGFLKLKDELIHSQTYADKGRIERKE
                     AILEEIYENYYENLPEEEQLIVDVTQARFDIYGSSDVTYGLGLVEEYFQQLLKKKYFS
                     VNDLLIIELYFFCCAMGLEDKEHFEELAQKVLLCSEYEDKASLVQMEKVLLSLFIQIQ
                     TEDSLIYIQTFEKIIAKTRHVFYRPHLFLLKAKYALFVDKNILEAESFYEKAISLAEL
                     LDDQVLVQRILAEKQIDFPTT"
     gene            complement(1320..1514)
                     /locus_tag="ACL29Z_001804"
     CDS             complement(1320..1514)
                     /locus_tag="ACL29Z_001804"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000757183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0070067.1"
                     /translation="MKKVLKYFLVFVFLFLMNIFIFKILATLGFQLIMSEKSYIVLPL
                     FSLIVLYMIDKRIRKKKKSL"
     gene            complement(1922..2047)
                     /locus_tag="ACL29Z_001805"
     CDS             complement(1922..2047)
                     /locus_tag="ACL29Z_001805"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001842754.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PncF family bacteriocin immunity protein"
                     /protein_id="HGR0070068.1"
                     /translation="MDFKSFIIGLVVGIFGPYMDDLIRKKFLKSSEKKTEKSVKK"
     gene            complement(2050..2280)
                     /gene="blpU"
                     /locus_tag="ACL29Z_001806"
     CDS             complement(2050..2280)
                     /gene="blpU"
                     /locus_tag="ACL29Z_001806"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001093487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-like peptide BlpU"
                     /protein_id="HGR0070069.1"
                     /translation="MNTKKMSQFEIMDTEMLACVEGGGCNWGDFAKAGVGGGAVRGLQ
                     LGIKTRTWQGAATGAAGGAILGGVAYAATCWW"
     gene            complement(2483..2773)
                     /locus_tag="ACL29Z_001807"
                     /pseudo
     CDS             complement(2483..2773)
                     /locus_tag="ACL29Z_001807"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase family protein"
     gene            complement(2819..3052)
                     /locus_tag="ACL29Z_001808"
     CDS             complement(2819..3052)
                     /locus_tag="ACL29Z_001808"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000136447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl carrier protein"
                     /protein_id="HGR0070070.1"
                     /translation="MTEKEIFDRIVTIIQERQGEDFVVTESLSLKDDLDADSVDLMEF
                     ILTLEDEFSIEISDEEIDQLQNVGDVVKIIQGK"
     gene            complement(3058..4050)
                     /gene="plsX"
                     /locus_tag="ACL29Z_001809"
     CDS             complement(3058..4050)
                     /gene="plsX"
                     /locus_tag="ACL29Z_001809"
                     /EC_number="2.3.1.274"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000717456.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0043811 - phosphate:acyl-[acyl carrier
                     protein] acyltransferase activity [Evidence IEA];
                     GO_process: GO:0008610 - lipid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate acyltransferase PlsX"
                     /protein_id="HGR0070071.1"
                     /translation="MKKIAVDAMGGDYAPQAIVEGVNQALSDFSDIEVQLYGDEAKIK
                     QYLTATERVSIIHTDEKIDSDDEPTRAIRNKKNASMVLAAKAVKDGEADAVLSAGNTG
                     ALLAAGFFIVGRIKNIDRPGLMSTLPTVDGKGFDMLDLGANAENTAQHLHQYAVLGSF
                     YAKNVRGIAQPRVGLLNNGTESSKGDPLRKETYELLAADESLNFIGNVEARDLMNGVA
                     DVVVADGFTGNAVLKSIEGTAMGIMGLLKTAITGGGLRAKLGALLLKDSLSGLKKQLN
                     YSDVGGAVLFGVKAPVVKTHGSSDAKAVYSTIRQIRTMLETDVVAQTAREFSGE"
     gene            complement(4047..4817)
                     /gene="recO"
                     /locus_tag="ACL29Z_001810"
     CDS             complement(4047..4817)
                     /gene="recO"
                     /locus_tag="ACL29Z_001810"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000616164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RecO"
                     /protein_id="HGR0070072.1"
                     /translation="MIQSITSQGLVLYNRNFREDDKLVKIFTEQVGKRMFFVKHAGQS
                     KLAPVIQPLVLARFLLRINDDGLSYIEDYHEVMTFPKINSDLFVMAYATYVAALADAS
                     LQDNQQDAPLFAFLQKTLELMEAGLDYQVLTNIFEIQILTRFGISLNFNECVFCHRVG
                     QAFDFSFKYGACLCPEHYHEDKRRCHLNPNIPYLLNQFQAIDFETLETISLKPGIKQE
                     LRQFMDQLYEEYVGIHLKSKKFIDSLADWGQLLKEEKK"
     gene            complement(4814..5983)
                     /locus_tag="ACL29Z_001811"
     CDS             complement(4814..5983)
                     /locus_tag="ACL29Z_001811"
                     /EC_number="2.6.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA];
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA];
                     GO_process: GO:0009058 - biosynthetic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HGR0070073.1"
                     /translation="MDLTKRFNKQLDKIQVSLIRQFDQVISEIPGVLRLTLGEPDFTT
                     PDHVKEAAKRAIDQNQSYYTGMSGLLTLRQAASDFVKEKYQLDYAPENEILVTIGATE
                     ALSATLTAILEEGDKVLLPAPAYPGYEPIVNLVGAEIVEIDTTENGFVLTPEMLEKAI
                     LEQGDKLKAVILNYPANPTGITYSREQLEPLAAVLRKYEIFVVCDEVYSELTYTGEAH
                     VSLGTMLRDQAIIINGLSKSHAMTGWRLGLIFAPATFTAQLIKSHQYLVTAANTMAQH
                     AAVEALTAGKNDAEPMKKEYIQRRDYIIEKMTALGFEIIKPDGAFYIFAKIPAGYNQD
                     SFAFLKDFAQKKAVAFIPGAAFGRYGEGYVRLSYAASMETIKEAMKRLEEYMREA"
     gene            6132..7142
                     /locus_tag="ACL29Z_001812"
     CDS             6132..7142
                     /locus_tag="ACL29Z_001812"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YeiH family protein"
                     /protein_id="HGR0070074.1"
                     /translation="MSFLSKNGAGILACLLISILSWYLGGFFPVIGAPVFAIFIGMLL
                     HPFLSSYKQLDAGLTFSSKKLLQYAVVLLGFGLNISQVFAVGQSSLPVILSTISIALI
                     IAYLFQRFFALDTKLATLVGVGSSICGGSAIAATAPVIHAKEKEVAQAISVIFFFNVL
                     AALIFPTLGTWLHLSNEGFALFAGTAVNDTSSVTAAASAWDSLYQSNTLESATIVKLT
                     RTLAIIPITLFLSYWQSRQQENKQSLQLKKVFPLFILYFILASLLTTLLTSLGVSSSF
                     FTPLKQLSKFLIVMAMSAIGLKTNLVAMVKSSGKSIVLGAICWIAIILTTLGMQTLIG
                     IF"
     gene            complement(7335..7772)
                     /locus_tag="ACL29Z_001813"
     CDS             complement(7335..7772)
                     /locus_tag="ACL29Z_001813"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0120225 - coenzyme A binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="CoA-binding protein"
                     /protein_id="HGR0070075.1"
                     /translation="MSQEFINPSDGVIRQYLATSKTLAVVGLSDREETTSNRVTKEMQ
                     ARGYKIIPVNPKAAGGEILGEKAYASLAEIPFPVDIVNVYRRSEFLPDVARDFLKADA
                     KIFWAQLGLESLEAKEILRDGGCDDIVMNRCIKREHTRLIEEA"
     gene            complement(7857..10490)
                     /gene="polA"
                     /locus_tag="ACL29Z_001814"
     CDS             complement(7857..10490)
                     /gene="polA"
                     /locus_tag="ACL29Z_001814"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014932012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA];
                     GO_function: GO:0008408 - 3'-5' exonuclease activity
                     [Evidence IEA];
                     GO_process: GO:0006261 - DNA-templated DNA replication
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase I"
                     /protein_id="HGR0070076.1"
                     /translation="MDKKKLLLIDGSSVAFRAFFALYQQLDRFKNAAGLHTNAIYGFQ
                     LMLSHLLERVEPSHILVAFDAGKTTFRTEMYADYKGGRAKTPDEFREQFPFIRELLDH
                     MGIRHYELAQYEADDIIGTLDKLAEQDGFDITIVSGDKDLIQLTDEHTVVEISKKGVA
                     EFEAFTPDYLMEEMGLTPAQFIDLKALMGDKSDNIPGVTKVGEKTGIKLLLEYGSLEG
                     IYENIDGMKTSKMKENLINDKEQAFLSKTLATIDTKAPIAIGLEDLVYSGPDVENLGK
                     FYDEMGFKQLKQALNVSSADVAKGLDFTIVDQISQDMLSEESIFHFELFGENYHTDNL
                     VGFAWSCEDKLYATDKLELLQDPIFKDFLEKTSLRVYDFKKVKVLLQRFGVDLQAPAF
                     DIRLAKYLLSTVEDNEIATIASLYGQTYLVDDETFYGKGVKKAIPEREKFLEHLACKL
                     AVLVETEPILLEKLSENGQLELLYDMEQPLAFVLAKMEIAGIVVKKETLLEMQAENEL
                     VIEKLTQEIYELAGEEFNVNSPKQLGVLLFEKLGLPLEYTKKTKTGYSTAVDVLERLA
                     PIAPIVKKILDYRQIAKIQSTYVIGLQDWILADGKIHTRYMQDLTQTGRLSSVDPNLQ
                     NIPARLEQGRLIRKAFVPEWEDSVLLSSDYSQIELRVLAHISKDEHLIKAFQEGADIH
                     TSTAMRVFGIERPDNVTANDRRNAKAVNFGVVYGISDFGLSNNLGISRKEAKAYIDTY
                     FERFPGIKNYMDEVVREARDKGYVETLFKRRRELPDINSRNFNIRGFAERTAINSPIQ
                     GSAADILKIAMIQLDKALVAGGYQTKMLLQVHDEIVLEVPKSELVEMKKLVKQTMEEA
                     IQLSVPLIADENEGATWYEAK"
BASE COUNT         3075 a         2579 c         1771 g         3217 t
ORIGIN      
        1 ctacattttc ctagattatc aaattacttt tatatcacta agactcaata aaagataatg
       61 tctatttaac ttttatacga ttactacctc ctttttagtt tacacttcct acatcataaa
      121 taaacatact caaccctcac aatctccaaa taactcttct atatcattga aaattgagtt
      181 tcatcctcta tactaatgta ggaaacctat taaaacattc ctttaatcca atataagaat
      241 accttgttcc attaatctct acccgatatt atagatagaa ccagactcct atacttaaaa
      301 ggacaaataa cgttccaacc ataataaacc tcctttcttt ttgagaacgt tttctttata
      361 ggtttagtat agcaaaaaca tgaaaaaaac aacctgactt agaagtcagg ttgttgggaa
      421 atctatctgt ttttctgcta aaattctctg aactaatacc tgatcgtcta gcaattctgc
      481 tagagaaatc gccttttcat agaaactttc tgcctctaaa atattcttgt ctacaaataa
      541 agcatatttt gcctttagca aaaatagatg aggtcggtaa aaaacatgtc ttgttttagc
      601 aataattttc tcaaatgttt gaatatatat cagactatct tctgtctgaa tttggataaa
      661 taggctcaga agaacttttt ccatttgaac taggctagcc ttatcttcat attctgaaca
      721 tagcaatact ttttgagcta actcctcaaa atgttcttta tcttctaatc ccatagcaca
      781 acaaaagaaa tacaattcaa taatcaacaa atcatttaca gaaaaatatt tcttttttaa
      841 taactgctgg aaatattctt ccactaaccc taaaccgtag gtcacatctg aactaccata
      901 aatatcaaaa cgagcttgtg tcacatccac aattaactgc tcttcctcag gcaaattctc
      961 ataatagttt tcatatattt cctcaagtat agcttctttt cgttcgattc ttcccttatc
     1021 agcgtaggtt tgagaatgaa tcagctcatc tttgagtttt aggaatcctt ttggaatctc
     1081 tataacctta acatccacaa tattctgtaa tgatactcca agtttatccg caatcaataa
     1141 taatttagga agtgttgcta aagcttgccc attttcaata cgtgctagct gacgaatcgt
     1201 caactctgat tcatcaccac aaatatctat ctgagttttt ccacaagatc gcctaatagt
     1261 tttgatttta taaccaattt cacgtttcaa ctcatccata gtaatactcc ttaagttgat
     1321 tacaaagatt tctttttctt cctaattctt ttgtcaatca tatataaaac gataagcgaa
     1381 aacagcggta gaacaatata actcttttca ctcattatca gctgaaatcc cagggttgct
     1441 agtatcttaa agatgaaaat attcatcaaa aatagaaaaa caaatactaa aaaatatttt
     1501 aaaaccttct tcatttcttt tcttcaactt tcctaatttc tacacctatt ttatcgaaaa
     1561 tatatataaa actccaaata aacacttcga ctgcactttt tttggcaaaa aatagacaga
     1621 acaaacatcc tatctactaa aaatatgata tgaaaggaaa ttgatttttt actgtcaccc
     1681 taggcaagct tgaaacaaat aaatcattga tagtaacact tacgacatcc tatttattac
     1741 ttcaatttct aatgtctctg ctatttctaa gctacctctg gtatgatcta ttcctagtca
     1801 gaatagataa caccgttcta aattacgatt catagttact ccttttttga ctcgttacta
     1861 taagactcct ctttacatgc gcaaaataat tttgattcag attcatcatt tatagttttg
     1921 attatttttt aacagatttt tctgttttct tctccgaaga ctttaaaaat ttttttctaa
     1981 ttaaatcatc catataagga ccaaatatac caactactaa accaataata aaacttttaa
     2041 aatccataat taccaccaac atgtcgctgc ataggccaca cctccaagta tagctcctcc
     2101 cgcagcacca gttgctgcac cttgccatgt tcttgtttta attcctagct gaagacctcg
     2161 tactgctcct cctccaacac ctgctttggc aaaatctccc caattgcatc cgccaccttc
     2221 aacgcaagca agcatctcag tatccataat ttcaaattgt gacatctttt ttgtattcat
     2281 aacgaatacc tcttttttat ttttaatatt tgtcttgtta caaacttgac aagtttagta
     2341 taacagtatc tattaatttt tttcatccaa atcttgaatt ggcatcgaaa cgtcttgaat
     2401 tagctttttt gtttcaaaat catctctatt tttaaaaaag atgttttcta atcacttttt
     2461 tactattaga cttcctgcaa aactagaatc ctagttcatg attgataatg ccagcaatca
     2521 aattcattcg taatccgaag tgtttacgat gatttcgata ggttgttgaa atcattttaa
     2581 acgtttttac tttggcaaag atgttctcaa ccttgcttct ctccttggat agcgcatggt
     2641 tataggcttt atcttcagct gttagcggct tgagtttgct ggatttacgt ggagtttgtg
     2701 cttgaagata tatcttcatg agcccttgat aaccactgtc agccaagatt ttaccagctt
     2761 gtccgatatt tctcatttct aaaaaccatc tacttccgtt gacttggaac tccgattact
     2821 attttccttg aatgatttta accacatctc ctacgttttg gagttggtca atttcttcat
     2881 cgctgatttc gatactaaat tcatcttcca gagtcaagat aaactccatc aagtcaacag
     2941 aatccgcatc caaatcgtct ttcagactca aggattctgt cacgacaaag tcctctccct
     3001 gtcgctcttg gataatggtc acaatacggt caaaaatttc tttttctgtc atctctttta
     3061 ttctcctgaa aattcacgcg cagtctgggc aaccacgtct gtttctagca tggtacggat
     3121 ctgacgaatc gtactataaa cagccttggc atcgcttgag ccatgagtct tgacaacagg
     3181 tgccttaaca ccaaacaaga ccgctccacc aacatctgaa taattgagct gttttttcaa
     3241 accactgagg ctgtccttga gaaggagggc acctagtttc gctcgaagac caccacctgt
     3301 aatagctgtc ttgagcaagc ccatgattcc catagctgtc ccttcgatgg atttgagcac
     3361 agcgtttccc gtgaaaccat ctgccacaac aacatctgca acgccattca tcaaatcacg
     3421 cgcttccacg tttccgataa agttcaaact ttcatcagcc gccagtaatt cataagtttc
     3481 cttacgaagc gggtcgccct tgctactctc tgttccgttg ttgagcaaac caacgcgtgg
     3541 ttgcgcaatg ccacggacat ttttagcata gaaggaacct agaaccgcat attgatggag
     3601 gtgctgggct gtattttctg cattggcacc aaggtctagc atgtcaaaac cttttccatc
     3661 aacggtaggc aaggtagaca tgagtccagg acggtcgata ttcttgatac gacccacgat
     3721 gaagaatcct gctgccaaca aggcacctgt attcccagcc gaaaggacag cgtctgcttc
     3781 accatctttg acagccttgg ctgccaatac catactggca tttttcttat tcctaatagc
     3841 tctcgtaggt tcatcatccg aatcaatctt ctcatccgta tggataatgc tgacgcgctc
     3901 tgtcgctgtc agatattgct tgattttagc ttcatctccg taaagttgaa cctcgatatc
     3961 tgaaaagtca gatagggctt gattgacacc ctcaacaatg gcctgaggtg cgtaatcgcc
     4021 ccccatggca tctactgcga tttttttcat ttcttttcct cttttagtaa ttgtccccag
     4081 tctgctaggg aatcaataaa tttctttgat tttaggtgaa tcccaacgta ctcttcatat
     4141 agttgatcca taaattggcg tagctcttgc ttgattccag gcttgagcga aatggtctcc
     4201 aaagtctcaa aatcaatagc ttgaaattga ttgagcagat aggggatatt gggattgaga
     4261 tgacaacgtc tcttatcctc atgataatgc tctggacaga ggcaggctcc atatttgaaa
     4321 gaaaagtcaa aagcctgacc aacccgatgg cagaagacac actcattaaa attgaggctg
     4381 attccaaatc gagtcaaaat ttgaatttca aaaatattgg tcaaaacctg ataatccaag
     4441 cctgcttcca tcaactccaa agtcttttgc aaaaaagcaa acaagggagc atcctgctga
     4501 ttgtcctgca aactagcatc tgcaagagct gccacatagg tcgcataggc catgacaaag
     4561 aggtcactat taatcttggg aaaagtcatg acctcatgat agtcttcgat gtaactgagt
     4621 ccgtcatcat tgattcgcaa gagaaatcgt gccagcacca agggctgaat aacaggcgcc
     4681 agcttagact gaccagcgtg tttgacaaaa aacatgcgtt tgccaacctg ctctgtaaaa
     4741 attttgacga gcttgtcatc ctcacgaaaa ttgcgattgt aaagcaccaa gccttgactc
     4801 gtgatagact gaatcatgct tctctcatgt actcctcaag tcgtttcatg gcttctttga
     4861 tagtctccat gctggctgca taagataggc ggacgtagcc ttccccgtaa cgtccaaagg
     4921 ctgcaccagg gataaaggca acggccttct tctgagcaaa atccttcaga aaagcaaagg
     4981 agtcttgatt gtagcccgct ggaattttag caaaaatata gaaggcaccg tctggtttga
     5041 taatctcaaa accaagagca gtcatttttt cgatgatata gtcccgacgt tggatatatt
     5101 ccttcttcat gggctccgca tcgtttttac cagccgtcaa ggcttctact gcagcatgtt
     5161 gcgccatggt atttgcggca gtgaccaagt actggtgact cttgattaac tgggctgtga
     5221 aggtcgcagg agcgaaaatc agccccaaac gccaacctgt catggcatgc gatttagaca
     5281 aaccattgat aataatagcc tggtctctca acatcgttcc tagagacaca tgggcttcgc
     5341 ctgtgtaggt caattctgag taaacctcat cacagacaac aaaaatttcg tacttgcgta
     5401 aaacagctgc caagggctct aactgctctc gactgtaggt aattcctgtc ggattggctg
     5461 gatagttgag aataaccgcc ttgagcttat caccctgctc caaaatggcc ttctccaaca
     5521 tctcaggagt caagacaaaa ccattttcag tcgtatcaat ctcaacaatt tctgccccaa
     5581 ctaagttaac aatcggttca tagcctggat aagcaggagc tggcaaaagt accttgtctc
     5641 cctcttccaa aatagccgtc aaagtcgcag ataaagcctc tgtcgcccca attgtaacca
     5701 agatttcatt ttcaggagca tagtccagtt ggtacttttc cttaacaaag tcactggctg
     5761 cctgacgtag agtcagcaga ccactcatcc ctgtatagta ggattggttc tgatcaatcg
     5821 ctcgcttggc cgcctccttg acatggtctg gcgttgtaaa atcaggttcc cccaaggtca
     5881 aacgcaagac cccaggaatc tccgaaataa cctggtcaaa ctgacgaatc aacgaaactt
     5941 gaattttatc taactgttta ttaaagcgct tagttaagtc catagatacc tcctactttc
     6001 aaaacgtatc tctattatac tacaaaagcc ccccgaccgc aaaaatacat tagagaatag
     6061 ctttccactt tctattttac ttttcctgtt tataggtcta taatggtaat agattttatt
     6121 tggaggtttt tatgtcattt ctatcaaaaa atggagcagg tatcttggcc tgccttctca
     6181 tttccatcct atcttggtac ttaggaggat tcttccctgt gattggcgcg cccgtttttg
     6241 ccattttcat aggcatgctc ctacatccct ttctctcgtc ctataaacaa ctggatgctg
     6301 gtttgacctt tagttccaag aagttgctcc aatatgccgt tgtcttgctt ggttttggtc
     6361 tcaatatctc gcaggtcttc gcagttggcc aatcttcact ccctgtcatc ctgtccacta
     6421 tctcaatagc tctgattatt gcctacctct tccagcgttt ctttgcactg gatacaaaac
     6481 tggctacctt ggttggagta ggttcttcta tctgtggggg ttctgccatt gcagcgacag
     6541 cgcctgttat ccatgctaag gaaaaggaag tagcccaagc catttccgtt atctttttct
     6601 tcaatgtctt ggctgcgctc atctttccaa ccctcggcac ctggcttcat ctatccaatg
     6661 aaggcttcgc cctctttgca gggactgcgg tcaacgacac ttcctctgta acggctgccg
     6721 ccagcgcttg ggacagtctt taccaaagca ataccctcga gtctgcaacc attgttaaac
     6781 tcacacgtac tttggccatt atccctatca cgctctttct atcctactgg caaagtcgcc
     6841 aacaagaaaa caagcaaagc ctacaactga aaaaagtctt cccacttttt atcctttact
     6901 ttatccttgc ctctctcctc actacactac tcacctctct aggtgtgtcc agtagtttct
     6961 ttacccctct caaacaactc tctaaattcc ttattgtcat ggccatgagt gctatcggtc
     7021 tcaaaaccaa tctggtcgct atggtcaaat ccagtggaaa atccattgtt cttggagcca
     7081 tctgctggat tgccatcatc ctcaccactc ttggtatgca gacccttatc ggcattttct
     7141 aacactcttc gaaaatctct tcaaaccacg tcaacgtcgc cttgccgtag gtatatgtta
     7201 ctgacttcgt cagttctatc tacaacctca aaacggtgtt ttgagcagcc cgcggctagt
     7261 ttcctagttt gctagtgtgc tctttgattt tcattgagta taacacaaaa ggtagcccat
     7321 cagctacctt tttcttatgc ttcctcaatc aagcgagtat gttctctctt gatacagcga
     7381 ttcatcacga tatcatcaca tccaccatca cgcaaaatct ctttcgcttc taaactttca
     7441 agtcctagct gtgcccaaaa aatcttggca tcagctttga gaaaatcacg cgccacatcg
     7501 ggcagaaatt cactgcgacg ataaacattg acaatatcta caggaaaagg aatttcagcg
     7561 aggctagcat aagccttttc acccaagatt tcgccacctg ccgccttggg attgactggg
     7621 atgattttat agccccgagc ctgcatttcc tttgttactc gattgctggt tgtttcttca
     7681 cggtcagaca aacccaccac agcaagggtt ttactcgttg cgagatactg acgaatcacg
     7741 ccatcacttg gattgataaa ttcttgactc atagaaatcc tcctttttca tcagtatagc
     7801 acattttgaa aaggtttgca gaattatact acaaaaaagg aggactagcc ccctttttat
     7861 ttagcctcgt accaggttgc cccttcattc tcatctgcga taagaggaac actgagttga
     7921 atggcttctt ccatggtttg tttcaccaat tttttcatct ctaccaattc agatttaggc
     7981 acttcaagga cgatttcatc gtgcacttgt aacagcatct tagtctgata accacctgca
     8041 accaaggctt tatccagctg aatcatggca atcttgagaa tatctgctgc cgaaccctgg
     8101 ataggtgagt tgatagcagt tcgctccgca aaaccacgaa tattgaagtt gcgcgaattg
     8161 atatctggca actcacggcg acgcttaaag agggtctcta catagccctt atcacgcgcc
     8221 tcccgcacca cttcatccat gtagttttta atacctggaa aacgttcaaa gtaggtatca
     8281 atgtaggctt tggcttcctt acgactaatt cccaaattat tagacaagcc aaagtctgaa
     8341 atcccataaa ccactccaaa gttaactgcc ttggcattgc gacggtcatt tgcagtcaca
     8401 ttatcaggac gctcaatgcc aaagacccgc atggctgtcg aagtatggat atctgccccc
     8461 tcttggaagg ccttaatcaa gtgctcatcc ttagaaatat gcgccaaaac gcgcaattca
     8521 atctgtgaat agtcagagct gagtagcaca ctatcctccc actctggcac aaaagccttc
     8581 cgaatcaagc gcccttgttc caatcgggca ggaatatttt gcaagtttgg atccacacta
     8641 gacaaacgcc cggtctgggt caaatcctgc atatagcgag tatgaatctt tccatcagcc
     8701 aaaatccagt cctgcaagcc aattacataa gtagattgaa tcttagcaat ttgacggtaa
     8761 tccaggattt tcttaacaat cggagcaata ggagcgagac gctccaacac atccactgct
     8821 gtcgaataac ctgtcttggt tttcttagtg tattctagag gaagtcccaa tttctcaaag
     8881 agaagcacgc ccaactgctt aggcgagttg acattaaact cctcaccagc cagctcgtaa
     8941 atctcttgag tcagtttttc aatgacaagc tcattttcag cctgcatctc aagcaaggtc
     9001 tctttcttga ccacaatccc agcaatttcc atcttggcaa gaacaaaagc cagaggttgc
     9061 tccatatcat aaagaagctc taattgccca ttttcgctga gtttttcaag taaaataggc
     9121 tctgtttcta ccaaaacagc aagtttacaa gctaagtgtt ccaagaattt ctcacgttca
     9181 ggaatggcct ttttaacacc cttaccgtag aaagtttcat catcaaccaa gtaagtctga
     9241 ccataaagac tagcgatggt cgcaatttca ttgtcctcca cagtcgaaag gaggtattta
     9301 gccaaacgga tgtcaaaagc aggcgcctgc aaatccacac caaaacgttg caaaagaact
     9361 ttaaccttct taaagtcata aactctcaga gatgtttttt ctaagaaatc cttgaaaatc
     9421 gggtcttgca acagctcaag cttgtctgtg gcatagagct tatcctcaca agaccaggca
     9481 aatccaacca aattatccgt atggtaattc tcaccaaaaa gctcaaagtg gaagatagac
     9541 tcttcactca gcatatcttg actgatttgg tcaacaatag taaaatccaa acccttagcc
     9601 acatcagctg acgacacatt taaagcctgc ttgagctgtt tgaatcccat ctcatcgtaa
     9661 aatttcccaa gattttcaac atctggacca ctatagacca agtcctctaa accaatcgca
     9721 atcggtgcct tggtatcaat ggtcgctagt gttttagaca aaaaggcctg ttccttgtca
     9781 ttgatgagat tttccttcat cttagaagtc ttcattccat caatattttc ataaatcccc
     9841 tcaagcgaac catactccag caagagctta atacccgtct tttcaccgac tttggtcacc
     9901 ccagggatat tatccgactt atcacccatg agcgccttga gatcgataaa ctgagctggt
     9961 gtgaggccca tttcttccat gaggtaatct ggcgtaaagg cctcaaactc agccacacct
    10021 ttcttggaaa tttcaaccac cgtatgctca tccgtcagct gaatcaaatc cttgtcccca
    10081 ctgacaatgg taatatcaaa accatcctgc tctgctagct tatccagcgt cccaatgatg
    10141 tcatccgcct catactgagc cagctcatag tgacgaatcc ccatatgatc cagcaactca
    10201 cgaatgaaag gaaattgctc acgaaactca tcaggagtct tggcccgacc acccttatag
    10261 tccgcataca tctctgtccg gaaggtcgtc tttcccgcat caaaagccac caaaatatga
    10321 ctcggctcaa cccgctccaa caaatgactc aacatcaact gaaaaccata aatcgcattg
    10381 gtatgcaaac cagccgcatt cttaaaacgg tccaactgct gatacagcgc aaaaaacgcc
    10441 cgaaaagcta cagaagaccc atcaatcaat aataattttt tcttatccat acacccatta
    10501 taaaggaaag aatcaaaaaa taccattggg aagagctaga gcaagtattt ttcaaacttt
    10561 ttccgaataa atagatagag ccagagaatt tagtaaacct agatttaaaa atgtgctata
    10621 atataatata ttgaatctat aa
//
LOCUS       DBEJAU010000059        10635 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC323 isolate 683620
            SAMN38261939-rid24807223.denovo.059, whole genome shotgun sequence.
ACCESSION   DBEJAU010000059 DBEJAU010000000
VERSION     DBEJAU010000059.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261939
            Sequence Read Archive: SRR26833919
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 10635)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10635)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576303.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576303.1
            Genome Coverage       :: 154x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/19/2025 01:05:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,121
            CDSs (total)                      :: 2,078
            Genes (coding)                    :: 1,943
            CDSs (with protein)               :: 1,943
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 36
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 72 of 135
            Pseudo Genes (incomplete)         :: 63 of 135
            Pseudo Genes (internal stop)      :: 51 of 135
            Pseudo Genes (multiple problems)  :: 46 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10635
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261939-rid24807223.denovo.059"
                     /strain="GPSC323"
                     /isolate="683620"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            complement(59..3049)
                     /gene="lanM"
                     /locus_tag="ACL29Z_001815"
     CDS             complement(59..3049)
                     /gene="lanM"
                     /locus_tag="ACL29Z_001815"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000875571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0009403 - toxin biosynthetic process
                     [Evidence IEA];
                     GO_process: GO:0018193 - peptidyl-amino acid modification
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type 2 lanthipeptide synthetase LanM"
                     /protein_id="HGR0070077.1"
                     /translation="MKYKIKNVHKTLFIKERYQILSERNDNSLNNFSLNNWRSTMSII
                     SEKTFEEMLKLNNYNKKIFSNTVNYDYTEEQIRLYSEYAKNSEWYKFAEGSFEIFRKH
                     PQRINFKKDFSRILEPFIINLLKLINNYLENKEYEWIDKNGNIFSSLVFYLEDLIYPW
                     IVKPLVLEINSLREKGLLEGESEQQRYKYFITLFDKEENILNFYNKYPVLLRQISESC
                     LRFYTYFIEILSNLENDFSVLEEELGLRGKLNDIKFGKGDTHSQGKTVLILFFDDAKI
                     VYKPKNLIINNSLNTIAEYIRKVDEKIRIRIPRTIAYSDHSYEEFIDYLPLEQKKKLP
                     EYYYNFGVLLAFIYLFNGSDIHFENLISYGDMPVIIDFETMLQQPLFDDKTGQSLLDT
                     LFHRVTRTLLLPTEGVKREDGLDVEMSALTGNFKKDAFNGQVLINLNTDKVKFDIGKI
                     DFEGGKNLPVRDGDIEFDKYIKDFKKGFRDFYLIFEELNKTEEFKMLLKANLYGLKTR
                     VLFRDTNSYASVLSFLYHPDFYEEMLDREKALENLWSNKFSNQGIVASECEQMRLLDI
                     PIFYTDTNINEIYDDFGNHFISLHQFSGYDYFMKYLPNNNLENLEKQLDIIEIYFPSF
                     DQRKKGYKLNLSNRKKLPNESLVTILHNEVENIADSLVINNIYDEYPIWSIPVNFKGS
                     KWCLEQTGNDMYRGRAGILLFMYYVKLLKDKSSYTQLYNKMLSAIPPSVSLSKTTFGL
                     TGDIGYFIVLSIIEDYDTNTLACLNYIKSVLTELEKTDFASVSNKSDYINGLLPLINT
                     LLRYYRRGIEKERVLRLVLSLGDTLYNDVSERDNSNFGYSFGHGLSGVIFTLKNIYKV
                     TRLKKYKELILQLVPREKIKIHSLKWCSGEFGTLVNHPQSVPEGIVASLDNDTFCHGS
                     MAIINFYIDYMKEMDTSMELESLLCSVVMNKSKEGEYRIVQTSNFPDFSLYTGVTGIA
                     YTFLRYIALNQNDKKIVIPSLLEI"
     gene            complement(3168..3356)
                     /gene="pneA2"
                     /locus_tag="ACL29Z_001816"
     CDS             complement(3168..3356)
                     /gene="pneA2"
                     /locus_tag="ACL29Z_001816"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000786759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-peptide bacteriocin subunit PneA2"
                     /protein_id="HGR0070078.1"
                     /translation="MKNDFVIGKSLKELSLEEMQLVYGGTDGADPRSTIICSATLSFI
                     ASYLGSAQTRCGKDNKKK"
     gene            complement(3363..3587)
                     /gene="pneA1"
                     /locus_tag="ACL29Z_001817"
     CDS             complement(3363..3587)
                     /gene="pneA1"
                     /locus_tag="ACL29Z_001817"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000181087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-peptide bacteriocin subunit PneA1"
                     /protein_id="HGR0070079.1"
                     /translation="MTNFNSNEKFCGKSLKSLSADEMSLIYGASDGAEPRWTPTPIIL
                     KSAAASSKVCISAAVSGIGGLVSYNNDCLG"
     gene            complement(3690..3860)
                     /locus_tag="ACL29Z_001818"
     CDS             complement(3690..3860)
                     /locus_tag="ACL29Z_001818"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001227862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PhrA family quorum-sensing system peptide"
                     /protein_id="HGR0070080.1"
                     /translation="MRKKRGIKKLVTFALLGVFMFSNTIPYQQFIQKNKQLEIRVQSQ
                     KKSNGLDVGKAD"
     gene            4052..4915
                     /locus_tag="ACL29Z_001819"
     CDS             4052..4915
                     /locus_tag="ACL29Z_001819"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001093609.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HGR0070081.1"
                     /translation="MNTLAEKFRLKRKELRLSQQTLAEGICEQSQISKIERGHFIPSA
                     DLLFKLSQRLEVPLDYFFNEQIEVKSNLSNFKHLSARLLDDRNYDDLEYLYKIEVERS
                     TFLTLEDRTYLEWIKAIIDFYQYDSKCEAISSLENILLKVSSNTLIYLKALNTLSNFY
                     SLVGREQEYEANYSHLIELYQTKNLDHQEFLFGYIRVRYNYAHYLVSKEKYNEAIQEA
                     LETIELCKQRQTSYQLAPLLILVGNAGAKFLDREQVKNYYIEARELCKIYNNPLMLMK
                     IENYLKELDTV"
     gene            5298..5918
                     /locus_tag="ACL29Z_001820"
     CDS             5298..5918
                     /locus_tag="ACL29Z_001820"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000839915.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0070082.1"
                     /translation="MKSMRILFLLALIQISLSSCFLWKECILSFKQSTVFFIGSMVFV
                     SGICAGVNYLYTRKQEVHSVLASKKSVKLFYSMLLLINLLGAVLVLSDNLFIKNTLQQ
                     ELVDFLLPSFFFLFGLDLLIFLPLKKYVRDFLAMLDRKKTVLVTILATLLFLRNPMTI
                     VSLLIYIGLGLFFAAYLVPNSVKKEVSFYGHIFRDLVLVIVTLIFF"
     gene            6004..6447
                     /gene="tsaE"
                     /locus_tag="ACL29Z_001821"
     CDS             6004..6447
                     /gene="tsaE"
                     /locus_tag="ACL29Z_001821"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000288243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0002949 - tRNA threonylcarbamoyladenosine
                     modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     ATPase subunit type 1 TsaE"
                     /protein_id="HGR0070083.1"
                     /translation="MYTKNEEELQALGERLGHLLAKNDVLILTGELGAGKTTFTKGLA
                     KGLQISQMIKSPTYTIVREYEGRLPLYHLDVYRIEGDADSIDLDEFIFGGGVTVIEWG
                     NLLGDALPDTYLELEILKEADGRRLNFQAKGLRAEKLLEELQYGV"
     gene            6437..6955
                     /locus_tag="ACL29Z_001822"
     CDS             6437..6955
                     /locus_tag="ACL29Z_001822"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000455540.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetyltransferase family protein"
                     /protein_id="HGR0070084.1"
                     /translation="MEYELLIREAEPKDAAELVAFLNRVSLETDFTSLDGDGILLTSE
                     EMEIFLNKQASSDNQITLLAFLNGKIAGIVNITADQRKRVRHIGDLFIVIGKRYWNNG
                     LGSLLLEEAIEWAQAGGILRRLQLTVQTRNQAAVHLYQKHGFVIEGSQERGAYIEEGK
                     FIDVYLMGKLIG"
     gene            6963..7979
                     /locus_tag="ACL29Z_001823"
     CDS             6963..7979
                     /locus_tag="ACL29Z_001823"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000239264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0070726 - cell wall assembly [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LCP family protein"
                     /protein_id="HGR0070085.1"
                     /translation="MVKKIIGMVLALLSVTVVGVGVFAYTIYQQGTETLAKTYKKIGE
                     ETKVIEATEPLTILLMGVDTGNVERTETWVGRSDSMILMTVNPKTKKTTMMSLERDIL
                     TRIESGNGQAHEAKLNSAYADGGAELAIETIQKMMNIHIDRYVMVNMRGLQKLVDAVG
                     GITVNNILGFPISISDQEEFNTISIGVGEQHIGGEEALVYARMRYQDPEGDYGRQKRQ
                     REVIQKVMEKALSLNSVGHYQEILKALSDNMQTNIDLSAKSIPNLLGYKDSFKTIETQ
                     QLQGEGEILQGVSYQIVSRAHMLEMQNILRRSLGQEEVTQLETNAVLFEDLFGRAPVG
                     DEDN"
     gene            8064..9320
                     /locus_tag="ACL29Z_001824"
     CDS             8064..9320
                     /locus_tag="ACL29Z_001824"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000642700.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence/damage-inducible protein A"
                     /protein_id="HGR0070086.1"
                     /translation="MKAEIIAVGTEILTGQIVNTNAQFLSEKLAEIGVDVYFQTAVGD
                     NEVRLLSLLEIASQRSSLVILTGGLGPTEDDLTKQTLAKFLGKALVFDPQAQEKLDIF
                     FALRPDYARTPNNERQAQIVEGAIPLPNETGLAVGGKLEVDGVTYVVLPGPPSELKPM
                     VLNQLLPKLMTGSKLYSRVLRFFGIGESQLVTILADLIDNQIDPTLAPYAKTGEVTLR
                     LSTKASSQEEANQALDILENQILDCQTFEGISLRDFCYGYGEETSLASIVVEELKRQG
                     KTIAAAESLTAGLFQATVANFSGASSIFKGGFVTYSLEEKSRMLDIPAKNLEEHGVVS
                     EFTAQKMAEQARSKTQSDFGISLTGVAGPDSLEGHPVGTVFIGLAQEQGTEVIKVNIG
                     GRSRADVRHIAVMHAFNLVRKALLSD"
     gene            9375..10541
                     /gene="recA"
                     /locus_tag="ACL29Z_001825"
     CDS             9375..10541
                     /gene="recA"
                     /locus_tag="ACL29Z_001825"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397020.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003697 - single-stranded DNA binding
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008094 - ATP-dependent activity, acting
                     on DNA [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase RecA"
                     /protein_id="HGR0070087.1"
                     /translation="MAKKPKKLEEISKKFGAEREKALNDALKLIEKDFGKGSIMRLGE
                     RAEQKVQVMSSGSLALDIALGSGGYPKGRIIEIYGPESSGKTTVALHAVAQAQKEGGI
                     AAFIDAEHALDPAYAAALGVNIDELLLSQPDSGEQGLEIAGKLIDSGAVDLVVVDSVA
                     ALVPRAEIDGDIGDSHVGLQARMMSQAMRKLGASINKTKTIAIFINQLREKVGVMFGN
                     PETTPGGRALKFYASVRLDVRGNTQIKGTGDQKETNVGKETKIKVVKNKVAPPFKEAV
                     VEIMYGEGISKTGELLKIASDLDIIKKAGAWYSYKDEKIGQGSENAKKYLAEHPEIFD
                     EIDKQVRSKFGLIDGEEVSEQDTENKKDEPKKEEAVNEEVTLDLGDELEIEIEE"
BASE COUNT         3464 a         1795 c         1957 g         3419 t
ORIGIN      
        1 tttttatatt gcttaatgag tggacacctc tattttagaa acaaaactat aaattaagct
       61 agatttcaag taatgagggg ataactatct ttttgtcatt ctgattcagt gcgatatacc
      121 ttaaaaaagt ataagcaata ccagtcacac ctgtatacaa agaaaaatct gggaaattgc
      181 ttgtttggac gatacgatac tctccttctt ttgatttatt cattacaaca ctacacaata
      241 aagactccaa ttccatacta gtatccattt ctttcatgta gtcgatgtaa aaatttatta
      301 tggccatact tccatggcaa aatgtatcat tatctaaact agctacaatt ccctctggaa
      361 cactttgggg atgattaact aatgtcccaa attctccact acaccacttc aaagaatgaa
      421 ttttgatttt ctccctagga actagttgta aaattaattc tttatatttt ttaagtcttg
      481 tcactttata aatatttttt aatgtaaaaa ttacacctga tagtccatgg ccaaaactat
      541 atccaaaatt actattatct ctctcgctta catcattata tagcgtatca cctaaactta
      601 atactagcct tagaacacgt tccttctcta ttcctctcct ataatatctt aacagtgtat
      661 taattaaagg tagaagacca ttaatatagt cagacttgtt tgaaacactt gcaaaatcag
      721 tcttttcaag ctcagttaaa acactcttta tataatttaa gcatgcgaga gtatttgtat
      781 cgtaatcctc tataatggat agaacaatga aatatcctat atccccagtt aaaccaaatg
      841 tggtcttaga taaagaaaca gatggcggaa ttgcagataa cattttattg tacagttgag
      901 tatatgatga tttatctttc aataatttta catagtacat aaacagtaat attccagctc
      961 tacccctata catatcatta cccgtttgtt caagacacca tttagaacct ttaaaattaa
     1021 caggtatact ccaaattgga tattcgtcat aaatattatt aataaccaaa gagtctgcaa
     1081 tattttctac ttcattatgc agaatagtaa ctaaactttc atttgggagt ttttttctat
     1141 tagataagtt taatttatat cctttttttc gctgatcaaa gcttggaaaa taaatttcaa
     1201 tgatatcaag ttgcttttct aaattttcca aattattatt aggtaaatat ttcataaaat
     1261 agtcatatcc agaaaattga tgtagggaaa taaaatgatt tccaaaatca tcgtagattt
     1321 cattgatatt tgtatctgta taaaaaatcg gaatatctaa taacctcatt tgttcacatt
     1381 cgcttgctac aataccttga ttagaaaact tattgctcca gagattttcc aatgcttttt
     1441 ctctatctaa catttcttca taaaaatcag gatgatataa aaaagatagt actgaagcat
     1501 agctatttgt gtctctaaaa agtacccttg tctttaaacc atacaagttt gcttttaata
     1561 gcattttaaa ttcttctgtt ttatttaact cttcaaatat cagataaaaa tccctaaaac
     1621 cttttttgaa atcttttata tacttatcaa attctatatc accatcccga acaggcaggt
     1681 ttttcccacc ttcaaaatca attttcccaa tatcaaactt taccttatca gtatttaaat
     1741 taattaaaac ttgaccatta aaagcatcct tcttaaaatt tcctgtaaga gcactcatct
     1801 caacatcaag accatcctcc ctttttactc cctctgttgg aagaagcaaa gttcgagtca
     1861 ccctgtgaaa cagggtatcc agcaaactct gaccagtttt atcatcaaat agaggttgct
     1921 gtaacattgt ttcaaagtct attattacag gcatatctcc ataggaaatt aaattttcaa
     1981 aatgtatatc actcccatta aataaatata taaatgctaa aagcacacca aaattataat
     2041 aatattcagg taattttttc ttttgctcta gaggtagata atcaataaat tcttcatagc
     2101 tgtgatccga ataagcaata gttcgaggta ttcttatcct aattttttca tcaacctttc
     2161 ggatatactc agcaatagta tttagtgagt tattgattat taaattttta ggcttgtaaa
     2221 caattttcgc gtcatcaaag aagagtatca aaacagtttt tccttggctg tgtgtatcac
     2281 cctttccaaa ttttatatca tttaatttcc cccttagccc taattcttct tctagcacac
     2341 taaaatcatt ttctaaattt gataaaattt ctataaaata agtatagaac cgaagacaag
     2401 actccgatat ttgcctcagt aaaacgggat atttgttata aaaatttaat atattctctt
     2461 ccttgtcaaa caatgttata aaatatttgt accgttgctg ctccgattcc ccttcaagta
     2521 aacctttttc acgcaatgaa tttatctcta aaaccaaagg tttaacaatc caaggataga
     2581 ttaaatcttc taaataaaat actagagagg aaaaaatatt tccattcttg tcaatccact
     2641 cgtattcttt attctctaga taattattga ttaatttaag caaattaata ataaagggtt
     2701 ccaaaattct agaaaaatct ttcttaaaat taattctttg gggatgtttt ctaaatattt
     2761 caaatgaacc ctccgcaaat ttataccatt ccgaattttt ggcatattct gaatatagtc
     2821 ttatctgttc ctcggtataa tcatagttca cagtgttaga aaatattttt ttattgtaat
     2881 tatttaattt caacatttct tcaaaagttt tttcagaaat aattgacatt gtagaacgcc
     2941 aattatttaa tgaaaagtta tttaaggaat tatcatttcg ttcagataat atttgatatc
     3001 tttccttaat aaacaatgtt ttatgcacat ttttaatttt atatttcatt tacttacctc
     3061 aaacctatac gacttactat tgttttaaaa aaaaaaaacc tctctcaaaa ttattagtta
     3121 cgagagagga aaataaagag caacttttat ttttaaaatt gaatatttta ttttttcttg
     3181 ttgtctttgc cacaacgagt ctgagctgac cccaaatatg atgcaataaa acttaatgta
     3241 gcagaacata taattgttga tctagggtca gcaccatctg tgccaccata aaccaattgc
     3301 atttcttcaa gagataattc tttcaaactc tttccgatta caaaatcatt tttcatttta
     3361 atttacccca aacaatcatt attgtagcta actagccccc caataccaga aacagctgca
     3421 ctaatgcata ctttcgagct agctgcagct gatttcaaaa taataggagt aggcgtccaa
     3481 cgtggctctg caccatcaga tgcaccataa attaaactca tttcatcagc agacaatgat
     3541 tttaaacttt ttccacaaaa tttttcgttt gaattaaagt tggtcataag taataactcc
     3601 tccttataaa aagttaaata agttgctcta tatttttcgt tttttcagat aaattataat
     3661 tctctcattc tcgtgcaaaa tatcgggttt taatccgcct tcccaacatc aagaccattg
     3721 gacttctttt gcgattgcac tcgaatctcc aattgtttat tcttctgaat aaactgttgg
     3781 taaggaattg tattactaaa cataaaaaca cctagcaatg caaatgtaac taatttttta
     3841 attccacgtt tttttctcat gcaatgaaac ccctttcttt ttccttgttt ttattctaac
     3901 agatatattt tatttagtca agtattttta tgtaattttt aacttttttt tttgtttatt
     3961 accataaaga attatttatt cctttaactt gctattttga actaaaaact ttataatgaa
     4021 attaagcaaa taggaaggtt tattatcttt aatgaataca ctcgcagaga aattcagatt
     4081 gaaaagaaaa gagttgagac tctcccaaca aactcttgca gaaggaattt gtgaacaaag
     4141 ccagattagt aaaattgaaa gaggtcattt tattccctcc gcagacttgt tattcaaact
     4201 ctctcaacga cttgaagtcc ctttggatta ctttttcaat gaacaaatcg aagttaagtc
     4261 taacctctct aatttcaaac atctatctgc tcgcctatta gatgacagaa attatgacga
     4321 tttagaatat ctttataaaa tagaggtaga acgaagcact tttctaacat tagaagaccg
     4381 aacttacctt gaatggatta aagctattat tgacttctat caatatgaca gtaagtgtga
     4441 ggcaatttct tcattggaaa atatattatt aaaagtctct tcaaatactc tgatttattt
     4501 aaaggcgttg aatactctat ctaatttcta ttccttagtg ggtcgtgaac aagaatatga
     4561 ggcaaactac tctcatttaa tagagttgta tcagacaaaa aatttggacc atcaagagtt
     4621 tttatttggc tacatcagag ttcgttacaa ctacgctcac tacctagtat caaaggaaaa
     4681 atataatgaa gccatccaag aagctcttga aacgattgaa ctctgtaaac aaagacagac
     4741 aagctaccaa ttggctcctc tacttattct tgtaggaaat gctggagcca aatttctaga
     4801 cagagaacaa gtcaaaaatt attatataga agcaagagag ttatgtaaga tttataacaa
     4861 tcctttaatg ttgatgaaga tagaaaatta tttgaaggaa ttagatactg tttagttaat
     4921 cttgacatta tagtttttct gaaacgttaa ataacctgta aggctgatag ttagattaat
     4981 actatcagcc ttataattat gtgactctga gtccgtctcg ctccgtgagg tgcgagacaa
     5041 aacaaccacc cgtttgacgg attttcatga tttcaaattt atattcttcg aaaatctctt
     5101 caaatcacgt cagctctatc tgcaatctca aaacagtgtt ttgagcaacc tgtggctagc
     5161 tacctagttt gatctttgat tttcattgag tattagtctc tagtgtttgt ttagcgtctt
     5221 aaagagacat ttgagaagat tagaaacagt tctctctttt ctcctagtat aatgattggt
     5281 aggaagggag agagaagatg aaatcaatga gaatcttatt tttgttagct ttaattcaaa
     5341 tcagtttgag tagctgtttc ctatggaagg aatgcatctt gtcctttaaa caaagtacag
     5401 tttttttcat cggaagcatg gttttcgttt caggaatctg tgctggagta aattatcttt
     5461 atacccgtaa gcaagaagtc catagtgtcc tagccagtaa gaagtctgtg aagctttttt
     5521 acagtatgtt actcttaatt aatttgttag gagctgttct tgttttgtca gataacttgt
     5581 tcatcaaaaa tacgctgcag caagaattag ttgacttttt attgccatcc ttctttttcc
     5641 tatttgggct agatttgctg atttttttac ccttgaaaaa atacgtgcgc gattttcttg
     5701 ctatgctaga cagaaaaaag acagtgttgg tgactatttt agcaacactt cttttcttaa
     5761 gaaatccaat gaccattgtc tcacttctga tttatattgg actgggcttg ttttttgcag
     5821 cctatcttgt cccaaattcg gttaagaagg aagtttcctt ttatggtcat attttccgag
     5881 atcttgtatt ggtcattgtt acgctcattt tcttttagag aaagcctgtt ttttatggat
     5941 gttatgatga taagtttagt aggaaaatag acacaaaaga aaagtttttg gtataataag
     6001 agtatgtaca caaaaaatga agaagagttg caagccttag gggagcgttt gggccatcta
     6061 ttagcaaaga atgatgtttt aatcttaact ggagaactgg gtgcaggtaa aacgaccttt
     6121 actaaaggac ttgcaaaagg attacagatt tctcaaatga ttaaaagtcc cacctatact
     6181 atcgtgagag agtatgaagg tcgacttcca ctttatcacc tagatgttta tcgtattgaa
     6241 ggagatgctg attctatcga cttggatgag tttatctttg gtggcggtgt gactgttatt
     6301 gagtggggaa atctcttagg agatgccttg ccagatactt atttagaatt ggaaattcta
     6361 aaagaagcag atggacgccg tttaaatttt caggcaaagg gtttgcgtgc tgagaaattg
     6421 ttagaggagc ttcaatatgg agtatgaatt gctcattagg gaagcagagc ccaaagatgc
     6481 agctgaatta gtggcctttt taaatcgtgt gagtttggag acagacttta ccagcctaga
     6541 cggagatggt attctcttga ctagtgagga gatggaaata ttcctcaaca agcaagctag
     6601 ttcggacaat cagataacct tacttgcatt cttaaatggc aaaattgctg gtattgtaaa
     6661 tattacagct gaccagcgta agagagtccg tcatattggg gatctcttca ttgtgattgg
     6721 aaaaagatat tggaataatg gcttgggaag tttgttgcta gaagaagcga tagagtgggc
     6781 acaagcaggt ggcattctgc gtcgtctcca actgactgtc caaactcgta atcaagcagc
     6841 agtccatctt tatcaaaagc atggctttgt cattgaaggt agccaagagc gtggggcata
     6901 tatagaagaa gggaaattta tcgatgttta cttgatgggt aaactgatag gttagtagaa
     6961 atatggttaa aaaaattatt ggaatggtgc tagctttact ttctgtaact gtagtaggag
     7021 taggtgtttt tgcttatact atttatcaac aagggacaga aaccttagct aaaacctata
     7081 aaaaaatcgg cgaagaaacc aaggttattg aagcgactga acctctaacc attctgttaa
     7141 tgggagtgga caccggaaat gttgaacgaa ctgaaacttg ggtcggtaga agtgatagca
     7201 tgatcttgat gacagtgaat cctaaaacga aaaaaacaac aatgatgagt ttagagcggg
     7261 atattctgac gcgcattgaa tcagggaatg gtcaggctca tgaagcgaaa ctgaactcag
     7321 catatgcaga tggtggagca gagcttgcta tagaaaccat tcaaaaaatg atgaatatcc
     7381 atattgatcg ctatgtgatg gtcaatatga gagggttgca aaaattagtg gatgcagtag
     7441 gaggtattac agtcaataat atcctaggtt tcccaatttc tatcagtgac caagaagaat
     7501 ttaataccat ttctatcggt gttggggagc aacatattgg gggagaagaa gccctagtct
     7561 atgcacgaat gcgttaccaa gatcctgagg gggattatgg tcgtcaaaaa cgtcaacgtg
     7621 aagttattca aaaagtcatg gaaaaagctc tcagtttaaa tagcgttggt cattatcaag
     7681 agattctaaa agctttgagt gacaatatgc agaccaatat tgatttgtct gcaaaaagta
     7741 tccctaactt gctaggctat aaagattcat ttaaaaccat tgaaactcag cagttgcagg
     7801 gtgaaggaga gatacttcaa ggtgtttctt accagattgt ttcgagagca catatgttgg
     7861 aaatgcaaaa tatactccga cgttctttgg gacaagaaga agttactcag cttgaaacca
     7921 atgcggtttt atttgaagat ttatttggca gagcacctgt tggtgatgaa gataattaac
     7981 ttttgataca aataaaaaaa tcaatcgtag gaaaattcct gcgatttttt caaaaaaata
     8041 cgaatagata ggtaggagga aacatgaaag cagaaatcat tgctgttgga acagagattt
     8101 tgacaggaca gattgtcaac accaatgccc agtttttgtc ggaaaaacta gctgagattg
     8161 gggtagatgt atattttcag acggctgtag gagacaatga agttcgtctc ttgtctttgc
     8221 ttgagattgc cagtcaacgt agcagtctgg tgattttgac aggcggtttg gggccaactg
     8281 aggacgacct aaccaaacaa accctagcta aatttttagg gaaagcatta gtctttgatc
     8341 ctcaggctca ggagaagttg gatatctttt ttgccctgcg accagactat gcccgaacac
     8401 cgaataacga aagacaagct caaattgtag aaggagcgat tccactgcca aacgaaacag
     8461 gactggctgt tggaggaaaa ttagaagtag acggagtgac ctatgtcgtc cttccaggtc
     8521 cgccaagtga attgaaaccc atggtcttaa accaacttct acccaagttg atgacaggga
     8581 gcaagctgta ttcccgagtt cttcgtttct ttgggattgg cgagagccag ctggttacga
     8641 ttttggctga tttaattgat aatcagatcg atcctacctt ggccccttat gccaagacag
     8701 gagaagtcac tctacgtctg tcaacaaagg ctagcagtca agaagaggcg aatcaagcgc
     8761 tggatatctt ggaaaatcaa atcttggact gccagacttt cgaaggaatt tctttacgag
     8821 acttttgcta tggttatggg gaagaaacta gtttagccag cattgtggta gaagaactga
     8881 aaaggcaagg gaaaaccatc gcggctgcag agagtttaac ggcaggtctt ttccaagcta
     8941 ccgtggcgaa tttttctgga gcttcaagta tatttaaggg tggttttgtg acctatagct
     9001 tggaggaaaa atcaaggatg ttggatattc ctgccaagaa tttggaagaa catggtgtgg
     9061 tgtctgaatt tacagctcag aagatggctg agcaggcacg aagcaagacc cagtctgatt
     9121 ttggaattag tttgaccgga gtggcaggac cagatagcct agaaggacac ccagttggga
     9181 cagtcttcat aggcttggcg caagagcaag gaactgaggt tatcaaggtt aatattggag
     9241 gcagaagccg agcagatgta cgtcatattg cggttatgca tgcctttaac ctagttcgca
     9301 aggctttatt aagtgactaa cttttgatat aatagtagat aggtctgagg atcattagaa
     9361 tgtaggagaa tagaatggcg aaaaaaccaa aaaaattaga agaaatttca aaaaaatttg
     9421 gggcagaacg tgaaaaggcc ttgaatgatg ctcttaaatt gattgagaaa gactttggta
     9481 aaggatcaat catgcgtttg ggtgaacgtg cggagcaaaa ggtgcaagtg atgagctcag
     9541 gttctttagc tcttgacatt gcccttggct caggtggtta tcctaaggga cgtatcatcg
     9601 aaatctatgg cccagagtca tctggtaaga caacggttgc ccttcatgca gttgcacaag
     9661 cgcaaaaaga aggtgggatt gctgccttta tcgatgcgga acatgccctt gatccagctt
     9721 atgctgcggc ccttggtgtc aatattgacg aattgctctt gtctcaacca gactcaggag
     9781 agcaaggtct tgagattgcg ggaaaattga ttgactcagg tgcagttgat cttgtcgtag
     9841 tcgactcagt tgctgccctt gttcctcgtg cggaaattga tggagatatc ggagatagcc
     9901 atgttggttt gcaggctcgt atgatgagcc aggccatgcg taaacttggc gcctctatca
     9961 ataaaaccaa aacaattgcc atttttatca accaattgcg tgaaaaagtt ggagtgatgt
    10021 ttggaaatcc agaaacaaca ccgggcggac gtgctttgaa attctatgct tcagtccgct
    10081 tggatgttcg tggtaataca caaattaagg gaactggtga ccaaaaagaa accaatgtcg
    10141 gtaaagaaac taagattaag gttgtaaaaa ataaggtagc tccaccgttt aaggaagccg
    10201 tagttgaaat tatgtacgga gaaggaattt ctaagactgg tgagcttttg aagattgcaa
    10261 gcgatttgga tattatcaaa aaagcagggg cttggtattc ttacaaagat gaaaaaattg
    10321 ggcaaggttc tgagaatgct aagaaatact tggcagagca cccagaaatc tttgatgaaa
    10381 ttgataagca agtccgttct aaatttggct tgattgatgg agaagaagtt tcagaacaag
    10441 atactgaaaa caaaaaagat gagccaaaga aagaagaagc agtgaatgaa gaagttacgc
    10501 ttgacttagg cgatgaactt gaaatcgaaa ttgaagaata agctgttaaa gcagtggaaa
    10561 aatccgctac tttttcgatt tttgattcaa gtttttagat tatatatagt agcttgaaat
    10621 aagatatgaa caact
//
LOCUS       DBEJAU010000060        10481 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC323 isolate 683620
            SAMN38261939-rid24807223.denovo.060, whole genome shotgun sequence.
ACCESSION   DBEJAU010000060 DBEJAU010000000
VERSION     DBEJAU010000060.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261939
            Sequence Read Archive: SRR26833919
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 10481)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10481)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576303.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576303.1
            Genome Coverage       :: 154x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/19/2025 01:05:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,121
            CDSs (total)                      :: 2,078
            Genes (coding)                    :: 1,943
            CDSs (with protein)               :: 1,943
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 36
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 72 of 135
            Pseudo Genes (incomplete)         :: 63 of 135
            Pseudo Genes (internal stop)      :: 51 of 135
            Pseudo Genes (multiple problems)  :: 46 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10481
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261939-rid24807223.denovo.060"
                     /strain="GPSC323"
                     /isolate="683620"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            22..1626
                     /locus_tag="ACL29Z_001826"
     CDS             22..1626
                     /locus_tag="ACL29Z_001826"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000006331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HGR0070088.1"
                     /translation="MSEYWFSTNVDQIDEVDGKQCLIYSYYNIKASRNVEVLKGRSGT
                     KKGLDYWEPYAPQKQYEMERLPKNKYIGSSSTDRWDGIEKNVVFCDCKEYVSAFDLFF
                     YHYNFKKISTQRSKQDFIRLRSKPVADILKNNTSSYTRYKKEMVIDNVKVDDKVCEII
                     SEIMDESYTDIQILTHKLYSKGDDIKASKTIWMKKSGKEYSEAFAGTGEARIILLVND
                     IVNAQSNSLILIDEPEISLHPSAIYKFKEFLLQECLNKKHQIIITTHSTQLIKDFPRE
                     AVKLLVKNGEKVDVIENIDYQDAFFELGDVYHSRKMIYVEDRLAKYILEFVITHSGSE
                     NLKQNLVVRYIPGGANQIICNNILNSSYLDSDNHYFWLDGDQNTNVSESNNLMNYLEN
                     GVVISDKIPESDNKNLDDIIKLITGCPIKFNVSGNKGQKNNIELIAKQRSFIDYWAKY
                     VSYLPFPTPEFFLANLCNSVDREGYDFSKDGNGKEYFRKKTQVALGIENITSEDIFQE
                     QRRAVSKIQPESSMFQCIKEKLEALF"
     gene            1647..1788
                     /locus_tag="ACL29Z_001827"
                     /pseudo
     CDS             1647..1788
                     /locus_tag="ACL29Z_001827"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006155197.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DNA (cytosine-5-)-methyltransferase"
     gene            2006..2809
                     /locus_tag="ACL29Z_001828"
     CDS             2006..2809
                     /locus_tag="ACL29Z_001828"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fic family protein"
                     /protein_id="HGR0070089.1"
                     /translation="MQPTYNIDNPNLSYEAKRDLWRIGFGLQKVDNLVPSAYMESLAE
                     KQSRGELTYEQVYEDATVYHHTVDASTEEADLVSLRIVELLSRRGFRFSPATLLAIHK
                     ELFQDIFEPSIPVGQFRQTNITKNEPVLNGESVVYSDYSMIQMTLDYDFNQEKQVAYA
                     TLTQADVVKQIQHFISGIWQIHPFREGNTRTVTVFLIQYLREFGFDIDNIPFQQHSKY
                     FRDALVLDNAKILQRRPEFLTAFFENLLLGGQNDLSSEKMYLDLDLDFS"
     gene            3306..5881
                     /locus_tag="ACL29Z_001829"
                     /pseudo
     CDS             3306..5881
                     /locus_tag="ACL29Z_001829"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000442363.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase family protein"
     gene            6182..7021
                     /gene="licT"
                     /locus_tag="ACL29Z_001830"
     CDS             6182..7021
                     /gene="licT"
                     /locus_tag="ACL29Z_001830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006270038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="BglG family transcription antiterminator LicT"
                     /protein_id="HGR0070090.1"
                     /translation="MIIKRILNHNAVIAQSKKDIDILLFGRGIAFGRKIGDKVNPIDI
                     EKSFFLKNRDNMTRFTEMFINVPLELVYITEKIINLGKITLGNNFDEIIYINLTDHIS
                     SSIERYKEGVIISNPLRWEISKYYKEEFELGKRALQIIKKELGIELPIDEAAFIALHF
                     VNANLENNFQESYKITEIIMGIEKIIQDFYCTEFNQDSIDYYRFITHIKLFAHRLVEN
                     TTYCDDDDEDLLALMKNKYPREYECGEQVAMFIQTEYNYLLTSSELVYLMAHIRRLTK
                     NLD"
     gene            7039..8877
                     /locus_tag="ACL29Z_001831"
     CDS             7039..8877
                     /locus_tag="ACL29Z_001831"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000120564.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_function: GO:0015573 - beta-glucoside transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0015759 - beta-glucoside transport
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="beta-glucoside-specific PTS transporter subunit
                     IIABC"
                     /protein_id="HGR0070091.1"
                     /translation="MSYKDTVQKILDVIGGEKNVNRVTHCVTRLRLELKDENLVNDDD
                     VKKIPGVIGIMKKNGQYQIILGNDVANYYKEFVKLGNFESDSVVQGHKGNILERIIEY
                     IAGSMTPIIPAMLGGGMLKVLVIILPMLGILQSDSQTIAFLTFFGDAPYYFLPLLLAY
                     SASQKLKVTSTLAMSVAGVLLHPNFVQMVQSGNPLSLFGAPVTPASYGSSVVPILIMV
                     WLMKYIEKMIAKLTPAVTKSFLQPTLVLLVSSCIALVVVGPIGVIVGEGLSNLVGQMY
                     GVAGWLTLAILGAIMPFIVMTGMHWAFAPIFLAASIATPDVLILPAMLGSNLAQGAAS
                     MAVALKSKNNNTKQIAFAAGFSALLAGITEPALYGVTLKYKKPLYAAMIGGGLAGLFA
                     GLTSVKAYLFAVPSLIALPQFIYSDVPSNIVNALIVAVISVVITFVLAYIFGIDEEES
                     SSNLEVKAGVSNKKMIFSPISGEIIPLSDVQDKTFSDKLIGDGVAIIPSEGKVYAPFD
                     GKITNIFPTKHAIGLKSDEGVELLIHIGLDTVELKGQGFISHVEEGDRVFKNQLIFEM
                     DLNLIKTKGYETVTPVIVTNTNDFLDVLILPNNQTIEHSKELLVIL"
     gene            8890..10305
                     /locus_tag="ACL29Z_001832"
     CDS             8890..10305
                     /locus_tag="ACL29Z_001832"
                     /EC_number="3.2.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000151865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016798 - hydrolase activity, acting on
                     glycosyl bonds [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HGR0070092.1"
                     /translation="MTIFPDDFLWGGAVAANQVEGAYNEDGKGLSVQDVLPKGGLGEA
                     TENPTEDNLKLIGIDFYHKYKKDISLFSEMGFNVFRTSIAWSRIFPKGDEEEPNEAGL
                     KYYDELFDELHAHGIEPLVTLSHYETPLYLARKYHGWIDRRMIHFYEKFARTVLERYK
                     DKVKYWLTFNEVNSVLELPFTSGGIDIPKENLSKQELYQAIHHELVASSLVTKIAREI
                     NSEFKVGCMVLAMPAYPMTPNPKDVWATHEYENLNYLFSDVHVRGYYPNYAKRYFKEH
                     DINIEFAAEDAELLKNYTVDFLSFSYYMSVTQSALPTQYNSGEGNIIGGLVNPYLESS
                     EWGWQIDPIGLRIILNRYYDRYQIPLFIVENGLGAKDQLIKDEFNNLTVQDDYRIQYM
                     KEHLLQVAEALQDGVEIMGYTSWGCIDCVSMSTAQLSKRYGLIYVDRNDDGNGTFNRY
                     KKMSFTWYKGVIESNGESLFK"
BASE COUNT         3476 a         1441 c         2087 g         3477 t
ORIGIN      
        1 ggttctccag ccaataaaag tgtgtctgaa tattggttta gtacaaatgt tgatcaaata
       61 gatgaagtgg atgggaaaca atgtttaatc tattcatatt ataacattaa agcttctaga
      121 aatgtagaag ttcttaaagg ccgttctgga acaaaaaaag gattagatta ttgggaacca
      181 tatgctcctc aaaaacaata tgagatggaa agattaccca aaaataaata tattggaagt
      241 tcttcgacag acagatggga tggcattgaa aaaaatgttg tcttttgtga ttgtaaagaa
      301 tatgtttctg cttttgattt atttttctat cactataatt ttaaaaaaat ttctactcaa
      361 cgtagtaaac aagattttat aagattacga tctaaaccag ttgctgatat tttaaagaat
      421 aatacaagta gctatacgcg ttataaaaag gaaatggtta tagataatgt taaagttgat
      481 gataaagttt gtgaaattat tagtgaaata atggatgaat cttatacaga cattcaaatt
      541 ttaacacata agttgtattc aaaaggtgat gatataaaag cttccaaaac tatttggatg
      601 aaaaaatctg gaaaagaata ttccgaggct tttgcaggaa caggtgaggc tagaattatt
      661 ttgttagtaa atgatatagt aaatgcgcaa tcaaattcat taatattaat agatgaacct
      721 gaaatctcac ttcatccgag tgcaatctat aaatttaaag agtttttact tcaagagtgt
      781 ttaaataaaa aacatcaaat tattatcact acacattcta cacaacttat aaaagatttt
      841 cctagagaag ccgtgaaact tttagtgaaa aacggagaaa aggtagatgt tattgaaaat
      901 attgattatc aggatgcatt ttttgaatta ggtgatgtgt atcattctag gaagatgatt
      961 tatgttgaag atagactagc taaatatatt ctagagtttg ttatcactca ttcaggtagt
     1021 gagaatctta aacagaattt agtagtgaga tatattcctg gtggagcaaa tcaaataatt
     1081 tgtaataata ttttaaactc atcgtattta gattccgata accattattt ttggcttgat
     1141 ggagatcaaa acactaatgt tagtgaatca aataatttaa tgaactatct tgaaaatggt
     1201 gttgttatat cagataaaat tcctgaatca gataataaaa atcttgatga tattataaaa
     1261 ttgataacgg gatgtccaat taaatttaat gtttcaggta ataaagggca aaaaaataat
     1321 attgaattaa ttgcgaaaca aagaagcttt atagattatt gggctaaata cgtttcttat
     1381 cttcctttcc caaccccaga gtttttttta gctaatttgt gtaacagcgt agatagggaa
     1441 ggttatgatt tttctaaaga tggcaacgga aaagaatatt ttagaaaaaa aactcaagta
     1501 gcgttaggaa tagagaatat aacttctgaa gatattttcc aggagcaaag aagagctgtt
     1561 tcaaaaatac agccagaatc atcaatgttt cagtgtatta aagaaaaatt agaggcattg
     1621 ttctaattcc ttagattggg tactacataa caaatttttt aaattcaaac ccgcaccaaa
     1681 aacaacattg caactttctt ctcaggtaat gtgttgggat ttgaacagac caacgagttc
     1741 atagtggtgt atgccaatga ctttgataag tctacgcgtc agacttatta gttcatttat
     1801 ccagatatat ctcgataatc atattattta gtcaaagaac atcccatatg agggcatgaa
     1861 atgctaagtt tagcttgctc actattaaga tgaagtatat atatttcata gaacctattg
     1921 tgaaggattt ttataatttt cgccaattcc atacctattt cacaatttac cgatgacaca
     1981 gaaaaacaat tgaaaggata tttctatgca accaacttac aacattgaca atccaaactt
     2041 gtcttatgaa gcgaagcgtg atttatggcg gataggtttt ggtctgcaga aagttgacaa
     2101 tctagtgcca tcagcgtata tggaatcttt ggctgagaaa cagtcccggg gtgaactgac
     2161 ttatgagcag gtttatgagg atgcaacggt ttatcatcat accgttgatg cgagtacgga
     2221 ggaggcagac ttggtttctt tgcgtatcgt agaactcttg tctcgaagag gttttagatt
     2281 tagtcctgcg accttacttg ctattcataa ggagttgttt caagatatat ttgaaccctc
     2341 tattccggtg gggcaatttc gtcagaccaa tatcacaaag aatgaacctg ttttgaatgg
     2401 tgaaagtgtt gtgtactctg attactccat gattcaaatg accttggatt atgattttaa
     2461 tcaggaaaaa caagttgcat atgcgacact aactcaggcg gatgtggtta aacaaatcca
     2521 gcattttatt tcaggaatct ggcagattca tccatttcgc gaaggaaaca ctcggacagt
     2581 aacggtcttt ttgattcagt atcttcgtga gtttggtttt gatattgata atataccatt
     2641 tcagcaacat tccaagtatt ttcgtgatgc cttggtatta gataatgcaa agattttaca
     2701 gcgacgtcct gagtttttaa cagctttttt tgaaaatctc ttgctcggtg gtcaaaatga
     2761 tttgtcttca gaaaaaatgt atctagattt agacctcgat ttttcataat ccaaatactg
     2821 agtaaacatt gaattttagg caaaaatgaa gtaaatattc tcacaagaaa acgtatatca
     2881 tcaaagtttt aggtcgcttg ataatatgcg ttttttgaat tttatagact gctcgtttaa
     2941 actctattta cttcgtacat tccggagcga gatggactat tagtcgcata caaaatgagt
     3001 gctattcgga ttttattttc gtgtacaatt tcagctattc ttgttataat cagcctatag
     3061 gaatcaagga ggtgactctt atggctgttt ttgcgtcttt ggatggaatt gtggtagaaa
     3121 tacttgatgt ctttttttct tttaatgggg atagtgagtt tttcttgtgt atagcatttt
     3181 gaagctggaa taggacgcca tgactgctaa aagatttcta taaattaatt tgattttcct
     3241 aatcaatttg ttcatatctt atttcattcc actgtaaacg tcttaaagac aagagtcagt
     3301 ttgtgatgga acgctctcgg ttcgaggaga tgttccaact tcaaagtagt cacttgacga
     3361 cgcaagaaaa attacaattg tttacctccg tgtttgctgg acgttatgat gtttatgcta
     3421 agaattttat caatgaacaa gggaaaattc agtattttcc ttcctatgat tatggttgga
     3481 agcagttgcc acctgaaaaa cggagtttcc agacattgac gaactccgtt ttgaaatctc
     3541 attttcgtgg ggaggcagct atcggtatct ttcctatgca cttagatgat agctgttatt
     3601 ttttggtact ggatttggat gaaggagatt ggaaagaagc tggtttaacc attcgaagaa
     3661 tagcaaggga acgccagatg gaagcccatt tagagatttc tcgttcgggt tacggactcc
     3721 atatttggtt cttctttgag gaagcgattc tgagtcgaaa ggctcgcctg tttggaaaga
     3781 aactattaga attggctatg caggaaagta tgcaactgtc ctttgattct tttgatggca
     3841 tgtttccaaa tcaggatgtt cttcctaaag gtggatttga taatttaatt tcccttcctt
     3901 ttcaaggaga agcttatcat caagggcgaa cggtctttgt ggatgaacat tttcagcctt
     3961 atgaagatca atggaggtat ctacaagaaa ttcagaggat ttcaactgct aaagtggcac
     4021 tgttaatcca agaggagtta ggcaagcaag aattggataa ggagttgaag gtcgttttat
     4081 ccaatatgat ccaacttgaa aaatcgtctg tgacatccaa ggcacttttt ttcttgaaaa
     4141 atatggcttc cttttctaat cccgaatttt atagtagatt gaaactagaa tagtatacct
     4201 ctgcttctaa aacattgtta gaaatcgatt tgactttcct gatcgatttg tcctgttatt
     4261 atttcatttt attatattta aagcaggcta tgcgacagcc aacctatcaa attcctgagc
     4321 gaatgtattt atttggagaa tccgattatt atttatggct gccaagaggc ttgttatatc
     4381 cattgcaaga taaatttaag caggtagttg tggaggatag gagaaaagta caaaggtcta
     4441 ttagagtagc atttaaggga gagcttactt tggagcaaga attagccctg tcagatatga
     4501 attctaaaga aaatggttta cttcatgcgg gacaggtttt ggaaagatcg ttttaggtgc
     4561 tgctcttatc tctgaacgta agacaaaaac cattatccta gttcataata gacaactctt
     4621 agaccaatga ctggatcgtt taaagtgttt tttgactttc gaagaggcag aagctacccg
     4681 ttatacacca tcaggtcgtg aaagggtaat aggctatgtc gggcagtacg gtggggctaa
     4741 gaaatgactg agtaaactgg ttgatgttgt tatgattcaa tctctattta agttggaaaa
     4801 tagtcaaagt cttttggatg agtatgagat gatgattgtg gatgagtgtc atcatatctc
     4861 tgccttgatg tttgaaaaag ttgttgctca gtttagaggg aagtatcttt acggtttgac
     4921 ggctacgcct gagcgtaaga atggtcatga acctattgtt tttcagagaa attgaaaaga
     4981 ccaaagcaag taattttata cagctcagtg attggattgc tacagactca gcgaggaatc
     5041 agttgattct caaggatatt ctagcccaag tggcagaagg acggaatatc ttggttttag
     5101 ttaatcgaat tcaacagata gatgtctttg aaaagttatt gaaagagaaa gaggttgatg
     5161 actgttacat tattagcgga aaaaccaaag tccgagaaag agaacgagtt tactggagac
     5221 gttagaacag ttagataaag ggtttgtttt gttgtctact ggaaaataca ttggcgaagg
     5281 ttttgactta cctcagttgg acacgcttat cttggcagca cccttttctt ggaaaaataa
     5341 tttgattcag tactcaggtc ggattcatag aaactacaag gataagtctt tggtgcggat
     5401 tttcgattat gtggatattc atgttcctta tttagaaaag atgtttcaga aacgacaagt
     5461 agcttatcga aagatggatt atcgtgccat tgagggtgag gagaaacaat tcgtttatgt
     5521 tgatagtaga tatgagaagg tgttgagaga ggacttagca ggggaaagac aggaatgtct
     5581 gcttatttta ccttatgtgc accagacaaa actgatgaat tttctaaaag aatttaggat
     5641 tagtcaaatt gagatatgta taccagagac ggttgcaaat aaagcatggc tagaccagtt
     5701 gaagagccag aaaattaaag tgtcttttac tcaatcaaaa atagtaacgc ctattctttt
     5761 ggtgaataag actattgttt ggtatggtgc aatgccatta ttagggaagg tagatgagat
     5821 gaccatatta cgtttggaat cagctagtat agtttctgaa ctagtggcag gtttacgata
     5881 gagaaaattt ttaaaaattt ctatgtatga ttttcatttc tttagtgaga ctgttgccat
     5941 tatcacattc gaatcacaca aaataaaaaa atttttataa gtacttgaca aatagattga
     6001 aatatcataa aataaaaacg gttacagagt tattgattat ttaagcttca tgtcaccatt
     6061 aaaaattgaa ataaaaggat gttatcacta atacaagtga gcaggaacct atttaatcac
     6121 atcagaagaa gtttcttgat gttttttaag taggttcctt ttattttaaa agggaaattt
     6181 tatgatcata aaacgaatac taaaccacaa tgccgtaatt gcgcaaagta aaaaagatat
     6241 cgatattctt ctttttggaa ggggaatagc ttttggaaga aaaattggag ataaagtaaa
     6301 tccaattgat attgagaaaa gtttttttct caaaaataga gataatatga cccgttttac
     6361 agagatgttt attaacgttc ctttggagtt ggtgtacatc accgaaaaaa taattaacct
     6421 aggtaaaata acattgggta ataattttga tgaaattatc tatattaatt taacggatca
     6481 tatttcttcg agcatagaac gttataagga aggagttatt atttcgaatc ccctacgctg
     6541 ggaaatctcg aaatattata aagaagaatt tgaacttggg aaaagggctt tacaaataat
     6601 aaaaaaagag ttaggtattg aacttccaat tgacgaagct gcattcatag cgctacattt
     6661 tgttaatgct aatttagaaa ataattttca agagtcgtat aaaatcactg aaataattat
     6721 gggaattgag aaaatcattc aagatttcta ttgtactgag tttaaccaag attctattga
     6781 ttattataga ttcataactc atataaaatt atttgcccat cgcttggttg aaaatacaac
     6841 ttattgtgac gatgatgatg aagacttgtt agcattaatg aaaaataaat atcctagaga
     6901 atatgaatgt ggtgaacagg tggcaatgtt tatacaaact gagtacaatt atttgttgac
     6961 ttctagtgaa ttagtttatt tgatggctca tattcgtcgc ttaacaaaaa atttagatta
     7021 atagaatagg agaataccat gagttataaa gatacggtac aaaaaatcct cgatgtaatt
     7081 ggaggtgaaa aaaatgtcaa tagagttacc cattgtgtaa cacgtttaag attagaatta
     7141 aaagatgaaa atttagtcaa tgatgatgat gtgaagaaga taccaggtgt aataggtatt
     7201 atgaaaaaga atggacaata tcaaattata cttggtaatg atgtagctaa ttattataaa
     7261 gaattcgtta aacttggcaa ttttgaatcc gattcagttg ttcaagggca caaagggaat
     7321 attttagaaa gaatcattga atatatcgct ggttccatga ctccaatcat tccagcaatg
     7381 ttagggggag gtatgctgaa agtcttggta attattttac caatgcttgg tatattgcaa
     7441 tcagattctc agactattgc ttttttgaca ttttttgggg atgctccata ttatttctta
     7501 ccgctgttat tagcttattc tgcatcacaa aaattaaaag taacatctac attagctatg
     7561 tctgtagcag gtgtacttct ccatccaaat tttgttcaaa tggtgcaatc agggaatcct
     7621 cttagtttat ttggtgcacc tgtgacacca gctagttatg gttcgtcagt cgttccaatt
     7681 cttattatgg tttggttgat gaaatatatt gaaaaaatga ttgctaaatt aacaccagct
     7741 gttactaaga gttttttgca acctacgcta gtattattag tatcaagctg tattgcctta
     7801 gttgtagtcg gacctattgg agtaattgtt ggtgaaggat tatcaaatct agttgggcaa
     7861 atgtatggtg tagctggatg gcttacatta gctattcttg gtgctattat gccatttatt
     7921 gttatgactg gaatgcattg ggcttttgca cctatttttt tggcggcatc tattgctact
     7981 ccagacgtat taattcttcc agcaatgtta gggtcaaact tagctcaagg ggctgcttcg
     8041 atggctgttg cattaaagag taaaaataat aatacaaaac aaattgcttt tgcagcaggt
     8101 ttctcagcct tacttgcagg gattaccgaa cctgcattat atggtgtgac tttaaaatat
     8161 aaaaaaccgc tttatgcagc tatgattggt ggtggattag cgggattatt tgcaggtctt
     8221 actagtgtta aagcgtatct atttgctgtc ccatctttga tagcgttgcc tcaatttatt
     8281 tattctgatg taccatcaaa tattgtaaat gctttaattg tggcggttat ttcggttgtt
     8341 attacctttg tattagctta tatatttgga atcgatgaag aagagagttc tagcaattta
     8401 gaagttaaag ctggagtttc aaataaaaaa atgatatttt ctcctatatc aggagaaatc
     8461 attccgttaa gcgatgtcca ggataaaaca ttttcagata aactaattgg agacggagta
     8521 gcgattatcc caagtgaagg taaggtttat gcaccatttg atgggaaaat tacaaatatt
     8581 tttccgacta agcacgcaat tggattgaag agtgatgagg gtgttgagtt actaattcat
     8641 attggattag atactgttga gctaaaaggt caaggtttta ttagtcatgt agaagaagga
     8701 gacagagttt tcaaaaatca gttgattttt gaaatggact tgaatttaat caagactaaa
     8761 ggctacgaaa cagttacacc agtaattgta acgaatacca atgattttct agatgtatta
     8821 atattaccta ataatcagac aatcgagcat tctaaggaat tactggtaat attataatgg
     8881 aggaaattta tgaccatttt tccagatgat tttctttggg gtggagctgt tgcagctaat
     8941 caagtagagg gagcatataa tgaagatggt aagggcttat cagttcagga tgtgttaccc
     9001 aaaggtggat taggagaagc aacagaaaat cctacagaag ataacttaaa attgataggt
     9061 attgattttt atcataaata taagaaagat atatccttgt tttctgaaat gggctttaat
     9121 gtttttcgta cttctattgc atggagtaga atttttccaa aaggagatga ggaagaacct
     9181 aacgaagctg ggttgaaata ttatgatgaa ttgtttgatg aactacatgc tcacgggata
     9241 gaaccacttg taactctttc acactatgag actccattat atttagcaag aaaatatcat
     9301 ggatggattg ataggagaat gattcatttt tatgaaaaat ttgctcgaac agttttagaa
     9361 aggtataaag ataaagttaa atattggctt acatttaacg aagtaaactc tgttttggaa
     9421 ttaccgttta ctagtggagg aatagatata cctaaggaga atctttcgaa acaagaatta
     9481 tatcaagcta tacatcatga attagtcgcc tcgagtttgg ttacaaaaat tgctcgtgag
     9541 attaattcag agtttaaggt ggggtgtatg gtattagcta tgccagctta tccaatgact
     9601 ccaaatccaa aagatgtatg ggcgactcat gagtatgaga atctaaatta tctattttca
     9661 gatgtgcatg ttagaggtta ttatccgaat tatgcaaaaa gatattttaa ggaacatgac
     9721 attaacatag agtttgcagc tgaagatgca gagttattaa aaaattatac tgtagatttt
     9781 ttatccttta gctattacat gagtgtaact caatctgctc ttccaacaca gtataattca
     9841 ggagaaggga atattattgg tggtttagta aatccttatt tagagtcttc tgagtgggga
     9901 tggcaaattg atccaattgg actacgtata attttaaata gatattatga ccgttatcaa
     9961 attccattat ttatagtgga aaacggatta ggtgctaaag atcaactaat aaaagatgaa
    10021 tttaataact taacagtcca agatgattat agaattcagt atatgaaaga acatttattg
    10081 caagttgctg aagctctaca ggatggtgtt gaaattatgg gctatacgtc ttggggatgt
    10141 attgactgtg tttctatgtc cactgcacag ctttctaaga ggtacggtct catttatgtt
    10201 gatcgaaatg atgatggaaa tggcacattc aatcgatata agaaaatgtc ctttacttgg
    10261 tataaaggag tgattgaatc aaatggagaa tccttattta aatagtttgt ttattgatga
    10321 ttagatatta tcacggttaa ggcaacatct cattgaatat gaaataaaga ggtttggaag
    10381 acatcaaatt ctaaacctct ttattttata gggggattaa ttaatttaat tttgttacag
    10441 agagccgatt ataaatagtt aacttaggat agattggtta t
//
LOCUS       DBEJAU010000061        10286 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC323 isolate 683620
            SAMN38261939-rid24807223.denovo.061, whole genome shotgun sequence.
ACCESSION   DBEJAU010000061 DBEJAU010000000
VERSION     DBEJAU010000061.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261939
            Sequence Read Archive: SRR26833919
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 10286)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10286)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576303.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576303.1
            Genome Coverage       :: 154x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/19/2025 01:05:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,121
            CDSs (total)                      :: 2,078
            Genes (coding)                    :: 1,943
            CDSs (with protein)               :: 1,943
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 36
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 72 of 135
            Pseudo Genes (incomplete)         :: 63 of 135
            Pseudo Genes (internal stop)      :: 51 of 135
            Pseudo Genes (multiple problems)  :: 46 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10286
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261939-rid24807223.denovo.061"
                     /strain="GPSC323"
                     /isolate="683620"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            87..1262
                     /gene="mutY"
                     /locus_tag="ACL29Z_001833"
     CDS             87..1262
                     /gene="mutY"
                     /locus_tag="ACL29Z_001833"
                     /EC_number="3.2.2.31"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000886125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0019104 - DNA N-glycosylase activity
                     [Evidence IEA];
                     GO_process: GO:0006284 - base-excision repair [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="A/G-specific adenine glycosylase"
                     /protein_id="HGR0070093.1"
                     /translation="MLDLKEYGIVMWPEEKVISFREKLLAWYDENKRDLPWRRSKNPY
                     HIWVSEIMLQQTRVDTVIPYYERFLDWFPTVESLATAPEESLLKAWEGLGYYSRVRNM
                     QAAAQQIMTDFGGQFPNTYEGISSLKGIGPYTAGAISSIAFNLPEPAVDGNVMRVLAR
                     LFEVNHDIGIPSNRKIFQAMMEILINPDRPGDFNQALMDLGSDIESPVNPRPEESPVK
                     DFSAAYQNGTMDRYPIKSPKKKPVPIYLKALVVKNSQGQFLLEKNESEKLLAGFWHFP
                     FIEVDNFSQEEQFDLFHQVAEESVNSGPSPEESFQQDYDLDVDWLDVCFDIVQHVFSH
                     RKWHVQIVAGQVSDFHDFSDREVRWLSPEEFKNYPLAKPQQKIWQAYAQANLDSSQD"
     gene            1317..2021
                     /gene="yycF"
                     /locus_tag="ACL29Z_001834"
     CDS             1317..2021
                     /gene="yycF"
                     /locus_tag="ACL29Z_001834"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000722069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator YycF"
                     /protein_id="HGR0070094.1"
                     /translation="MKKILIVDDEKPISDIIKFNMTKEGYEVVTAFNGREALEQFEAE
                     QPDIIILDLMLPEIDGLEVAKTIRKTSSVPILMLSAKDSEFDKVIGLELGADDYVTKP
                     FSNRELQARVKALLRRSQPMPVDGQEADSKPQPIQIGDLEIVPDAYVAKKYGEELDLT
                     HREFELLYHLASHTGQVITREHLLETVWGYDYFGDVRTVDVTVRRLREKIEDTPSRPE
                     YILTRRGVGYYMRNNA"
     gene            2014..3363
                     /gene="vicK"
                     /locus_tag="ACL29Z_001835"
     CDS             2014..3363
                     /gene="vicK"
                     /locus_tag="ACL29Z_001835"
                     /EC_number="2.7.13.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000886221.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall metabolism sensor histidine kinase
                     VicK"
                     /protein_id="HGR0070095.1"
                     /translation="MLDLLKQTIFTRDFIFILILLGFILVVTLLLLENRRDNIQLKQI
                     NQKVKDLIAGDYSKVLDMQGGSEITNITNNLNDLSEVIRLTQENLEQESKRLNSILFY
                     MTDGVLATNRRGQIIMINDTAKKQLGLVKEDVLNRSILELLKIEENYELRDLITQSPE
                     LLLDSQDINGEYLNLRVRFALIRRESGFISGLVAVLHDTTEQEKEERERRLFVSNVSH
                     ELRTPLTSVKSYLEALDEGALCETVAPDFIKVSLDETNRMMRMVTDLLHLSRIDNATS
                     HLDVELINFTAFITFILNRFDKMKGQEKEKKYELVRDYPINSIWMEIDTDKMTQVVDN
                     ILNNAIKYSPDGGKITVRMKTTEDQMILSISDHGLGIPKQDLPRIFDRFYRVDRARSR
                     AQGGTGLGLSIAKEIIKQHKGFIWAKSEYGKGSTFTIVLPYDKDAVKEEVWEDEVED"
     gene            3365..4174
                     /locus_tag="ACL29Z_001836"
     CDS             3365..4174
                     /locus_tag="ACL29Z_001836"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861619.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HGR0070096.1"
                     /translation="MSEIGFKYSILASGSSGNSFYLETSKKKLLVDAGLSGKKITSLL
                     AEINRKPEDLDAILITHEHSDHIHGVGVLARKYGMDLYANEKTWQAMENSKYLGKVDS
                     SQKHIFEMGKTKTFGDIDIESFGVSHDAVAPQFYRFMKDDKSFVLLTDTGYVSDRMAG
                     IVENADGYLIEANHDVEILRSGSYAWRLKQRILSDLGHLSNEDGAEAMIRTLGNRTKK
                     IYLGHLSKENNIKELAHMTMVNQLAQADLGVGVDFKVYDTSPDTATPLTEI"
     gene            4265..4507
                     /gene="relB"
                     /locus_tag="ACL29Z_001837"
     CDS             4265..4507
                     /gene="relB"
                     /locus_tag="ACL29Z_001837"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001853822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0110001 - toxin-antitoxin complex
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelB family
                     antitoxin"
                     /protein_id="HGR0070097.1"
                     /translation="MTTITLKVSEADKTFMKAMAKFEGVSLSELIRTKTLEALEDEYD
                     ARVADLAYQEYLEDLEKGVEPITWEEMMHDLGLKDE"
     gene            4509..4763
                     /locus_tag="ACL29Z_001838"
     CDS             4509..4763
                     /locus_tag="ACL29Z_001838"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008657 - DNA topoisomerase type II
                     (double strand cut, ATP-hydrolyzing) inhibitor activity
                     [Evidence IEA];
                     GO_function: GO:0042803 - protein homodimerization
                     activity [Evidence IEA];
                     GO_process: GO:0030541 - plasmid partitioning [Evidence
                     IEA];
                     GO_process: GO:0051290 - protein heterotetramerization
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="HGR0070098.1"
                     /translation="MYKLVPTRRFIKQLKKLDRYTQKLITNYLQINVLEDPRRHGKAL
                     VGNRVGQWRYRIGNYRVIVQIVDDELVVATLEVGHRRDIY"
     gene            4810..5583
                     /locus_tag="ACL29Z_001839"
     CDS             4810..5583
                     /locus_tag="ACL29Z_001839"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000731134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ion channel"
                     /protein_id="HGR0070099.1"
                     /translation="MKKKWFFADYYDTTIILLALISVILVLLGFAEMIDLDNPPYSII
                     DLVIWGVFVIDYSWRFFITKRKWRFILENVFDLLAILPLNAIFTVFRLGRIFRLVKLT
                     KLLKLTRLLRIIGLTGKLERKISRFLRTNGLIYILYVNIFIILVGSSILSVVEEKSFS
                     DSLCWALVTVTTVGYGDIVPVSLLGKWLAVLLMLVGIGTIGMLTSALTNFFVKDNPDE
                     QIKLDKLQDELSSPRILLEKQSKKIEELHKMIQDLIEKT"
     gene            complement(5846..6832)
                     /locus_tag="ACL29Z_001840"
     CDS             complement(5846..6832)
                     /locus_tag="ACL29Z_001840"
                     /EC_number="1.1.1.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019768616.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004459 - L-lactate dehydrogenase activity
                     [Evidence IEA];
                     GO_process: GO:0006096 - glycolytic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="L-lactate dehydrogenase"
                     /protein_id="HGR0070100.1"
                     /translation="MTSTKQHKKVILVGDGAVGSSYAFALVNQGIAQELGIIEIPQLH
                     EKAVGDALDLSHALAFTSPKKIYAAQYSDCADADLVVITAGAPQKPGETRLDLVGKNL
                     AINKSIVTQVVESGFKGIFLVAANPVDVLTYSTWKFSGFPKERVIGSGTSLDSARFRQ
                     ALAEKLDVDARSVHAYIMGEHGDSEFAVWSHANIAGVNLEEFLKDTQNVQEAELIELF
                     EGVRDAAYTIINKKGATYYGIAVALARITKAILDDENAVLPLSVFQEGQYGVENVFIG
                     QPAVVGAHGIVRPVNIPLNDAETQKMQASAKELQAIIDEAWKNPEFQEASKN"
     gene            7026..9494
                     /gene="gyrA"
                     /locus_tag="ACL29Z_001841"
     CDS             7026..9494
                     /gene="gyrA"
                     /locus_tag="ACL29Z_001841"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001152996.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003916 - DNA topoisomerase activity
                     [Evidence IEA];
                     GO_function: GO:0003918 - DNA topoisomerase type II
                     (double strand cut, ATP-hydrolyzing) activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006259 - DNA metabolic process [Evidence
                     IEA];
                     GO_process: GO:0006265 - DNA topological change [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA gyrase subunit A"
                     /protein_id="HGR0070101.1"
                     /translation="MQDKNLVNVNLTKEMKASFIDYAMSVIVARALPDVRDGLKPVHR
                     RILYGMNELGVTPDKPHKKSARITGDVMGKYHPHGDSSIYEAMVRMAQWWSYRYMLVD
                     GHGNFGSMDGDSAAAQRYTEARMSKIALEMLRDINKNTVDFVDNYDANEREPLVLPAR
                     FPNLLVNGATGIAVGMATNIPPHNLGETIDAVKLVMDNPEVTTKDLMEVLPGPDFPTG
                     ALVMGKSGIHKAYETGKGSIVLRSRTEIETTKTGRERIVVTEFPYMVNKTKVHEHIVR
                     LVQEKRIEGITAVRDESNREGVRFVIEVKRDASANVILNNLFKMTQMQTNFGFNMLAI
                     QNGIPKILSLRQILDAYIEHQKEVVVRRTRFDKEKAEARAHILEGLLIALDHIDEVIR
                     IIRASETDAEAQAELMSKFKLSERQSQAILDMRLRRLTGLERDKIQSEYDDLLALIAD
                     LADILAKPERVSQIIKDELDEVKRKFSDKRRTELMIGQVLSLEDEDLIEESDVLITLS
                     NRGYIKRLDQDEFTAQKRGGRGVQGTGVKDDDFVRELVSTSTHDHLLFFTNKGRVYRL
                     KGYEIPEYGRTAKGLPVVNLLKLDEDESIQTVINVESDRSDDAYLFFTTRHGIVKRTS
                     VKEFANIRQNGLKALNLKDEDELINVLLAEGDMDIIIGTKFGYAVRFNQSAVRGMSRI
                     ATGVKGVNLREGDTVVGASLITDQDEVLIITEKGYGKRTVATEYPTKGRGGKGMQTAK
                     ITEKNGLLAGLMTVQGDEDLMIITDTGVMIRTNLANISQTGRATMGVKVMRLDQDAQI
                     VTFTTVAVAEKEEVGTENETEGEA"
     gene            9494..10237
                     /gene="srtA"
                     /locus_tag="ACL29Z_001842"
     CDS             9494..10237
                     /gene="srtA"
                     /locus_tag="ACL29Z_001842"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000078846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sortase SrtA"
                     /protein_id="HGR0070102.1"
                     /translation="MSQKNNKKKNKRKNLLTNILAGFLILLSLALIFNTQIRNIFIVW
                     NTNKYQVSQVSKEKLEENQDTEGNFDFDSVKAISSEAVLTSQWDAQKLPVIGGIAIPE
                     LEMNLPIFKGLDNVNLFYGAGTMKREQVMGEGNYSLASHHIFGVDNANKMLFSPLDNA
                     KNGMKIYLTDKNKVYTYEIREVKRVTPDRVDEVDDRDGVNEITLVTCEDLAATERIIV
                     KGDLKETKDYSQTSNEILTAFNQPYKQFY"
BASE COUNT         3187 a         1739 c         2291 g         3069 t
ORIGIN      
        1 tagatagaaa agttatatac tatctattga aaatattata aatcagatac aaagacaggt
       61 gaaaccttct gtgttatact agagatatgt tagatttgaa agaatacggt atcgtcatgt
      121 ggccggagga gaaagtcatt tctttccgtg agaaacttct cgcttggtat gatgaaaaca
      181 aaagagattt gccttggagg agaagtaaaa atccttatca catctgggta tctgaaatca
      241 tgcttcagca gaccagggtg gatacagtta tcccttacta cgaaagattt ttggactggt
      301 ttccaactgt cgaaagtctg gcaactgcgc ctgaggagag tttactgaaa gcttgggagg
      361 gcttgggtta ttattctcga gttcgcaata tgcaggctgc agcccagcag attatgactg
      421 actttggtgg ccaatttcca aatacctatg aaggaatttc cagcttgaaa gggattggac
      481 cttacacagc aggagccatt tccagtattg cttttaactt gcctgagcca gctgtagatg
      541 gtaatgtcat gcgggtcttg gcgcgtctgt ttgaagtcaa ccacgatatt gggattccaa
      601 gtaatcgaaa aatttttcag gcaatgatgg agatcttgat taatccagat cgtccgggtg
      661 attttaatca agccttgatg gacttagggt ctgatattga gtctcctgta aatcccagac
      721 ctgaagaaag cccagtcaag gactttagtg cggcatatca gaatggaacc atggaccgtt
      781 atccaattaa atctcctaag aaaaagccgg ttcctattta tcttaaagcc ttagttgtga
      841 aaaattctca aggacaattt ttacttgaaa aaaatgaaag cgaaaagctc ttggcaggtt
      901 tttggcattt cccctttata gaagttgata acttttcgca agaagagcag tttgacctct
      961 ttcatcaggt tgcggaagaa agtgtgaact ctggccccag tccagaagag agtttccagc
     1021 aggactatga cctagatgtt gattggcttg atgtttgttt tgatatagtc cagcatgttt
     1081 ttagtcatcg aaaatggcat gtacagattg tagcaggtca ggtgagtgac ttccatgatt
     1141 tttcagatag ggaagttcgt tggctttcac cagaagaatt caagaattac ccacttgcca
     1201 aaccccaaca aaaaatctgg caggcttatg cacaagccaa cttagacagt agccaagact
     1261 agctattgtg tcttctgact attttttggt ataatagtag agaaaaaggt gaacatatga
     1321 aaaaaatact aattgtagat gatgagaaac caatctcgga tattatcaag tttaatatga
     1381 ccaaggaagg ttacgaagtt gtaactgctt ttaatggtcg tgaagcgcta gagcaatttg
     1441 aagcagagca accagatatt attattctgg atttgatgct tccagaaatt gatggtttag
     1501 aagttgctaa gaccattcgt aagacaagca gtgtgcccat tcttatgctt tcagccaaag
     1561 atagtgaatt tgataaggtt atcggtttgg aacttggggc agatgactat gtaacaaaac
     1621 ccttctccaa tcgtgagttg caggcgcgtg ttaaagctct tctgcgtcgt tctcaaccta
     1681 tgccagtaga tggtcaggaa gcagatagta aacctcaacc tatccaaatt ggggatttag
     1741 aaattgttcc agacgcctac gtggctaaaa aatatggcga agaactagac ttaacccatc
     1801 gtgaatttga gcttttgtat catttagcat cgcatacagg tcaagtcatc acgcgcgaac
     1861 acttgcttga gactgtctgg ggttatgact attttggtga tgtccgtaca gttgatgtga
     1921 ctgtacgacg tctgcgtgag aagattgaag atacgcccag ccgaccagag tatatcttga
     1981 cgcgccgtgg tgtagggtat tacatgagaa ataatgcttg atttactgaa acaaaccatt
     2041 tttaccagag attttatctt tatcctgatt ttgttaggtt tcatccttgt tgtgaccctc
     2101 ttattactgg aaaatagacg tgataatatt cagttgaagc aaatcaatca aaaggttaaa
     2161 gatttgattg caggagatta ttccaaggtt cttgatatgc aaggtgggtc tgaaatcacc
     2221 aatattacca ataatttgaa tgacttgtcg gaggttattc gtctcactca ggaaaatcta
     2281 gaacaagaga gtaagaggct aaatagtatt ctgttttata tgacagatgg ggttcttgcg
     2341 accaaccgtc ggggtcagat tatcatgatt aacgatacag ccaagaagca actggggttg
     2401 gttaaggaag atgttctgaa tagaagcatt ttggaattgc tcaagataga agaaaactat
     2461 gaattgcgtg atttgattac ccaaagtcca gaattgttgc tagattccca agatatcaat
     2521 ggcgaatatt taaaccttcg agttcgcttt gccttgatac gtcgagagtc tggctttatt
     2581 tcaggtttgg tggctgtttt gcatgatacg acggagcagg agaaggaaga acgcgaacga
     2641 agactctttg tttccaatgt tagccatgag ttacggactc ctctgactag cgtaaaatcc
     2701 tatcttgaag ccttggatga gggggctttg tgtgaaactg tagcaccaga ctttatcaag
     2761 gtttctcttg atgagaccaa ccgtatgatg cgcatggtga cggatctcct ccatctttca
     2821 cgtattgata atgctaccag tcacctagat gtggaactga ttaacttcac tgcttttatt
     2881 acctttatcc tcaatcgttt tgacaagatg aaaggacagg aaaaggagaa aaaatatgag
     2941 ttggtgagag attatcccat caattctatc tggatggaaa ttgatacaga taagatgacg
     3001 caggttgtcg acaatatttt aaataatgct attaagtatt cgccagatgg gggtaaaatc
     3061 actgtcagaa tgaagacaac tgaagaccag atgattttat ccatttctga ccacggtttg
     3121 gggattccta agcaggattt accacgtatc tttgaccgtt tctatcgtgt ggatcgtgct
     3181 agaagtcgtg cacaaggtgg tacaggtcta ggactgtcta tcgctaaaga aattatcaaa
     3241 caacataagg gctttatttg ggccaagagt gaatacggca agggttcaac ctttaccatt
     3301 gtgctccctt atgataagga tgcagtgaaa gaagaagtat gggaggatga agtagaagac
     3361 tagaatgagt gaaataggct ttaaatacag tattttagcg tcgggttcca gtggaaattc
     3421 tttttatctg gaaacctcaa aaaagaagct tttagtagat gcaggcttgt ctggcaagaa
     3481 aattaccagt ctgctagctg aaattaaccg taagccagaa gacctggatg ccatcttgat
     3541 tacccatgag cattcagatc atatccatgg agtaggcgtt ttggctcgca agtatggtat
     3601 ggatctttat gccaatgaaa agacctggca agctatggaa aatagtaaat atcttggcaa
     3661 ggtggattct tcgcaaaagc atatttttga aatgggtaaa accaaaacct ttggagatat
     3721 cgacatcgag agttttggtg taagccatga tgcagtcgca ccgcagttct atcgctttat
     3781 gaaggatgat aagagttttg tccttttgac agatacaggt tatgtcagtg accgtatggc
     3841 gggcattgtc gaaaatgcgg atggctatct tatcgaggcc aaccatgatg tagagatttt
     3901 gcgatcaggt tcttacgctt ggcgactcaa acaacgaatc ctatctgacc ttggtcacct
     3961 ttctaacgag gacggtgctg aagctatgat tcggacgcta ggaaatcgta ctaagaagat
     4021 ttaccttggg catttatcta aggaaaacaa tatcaaggaa ctggctcata tgaccatggt
     4081 caatcagctg gctcaagctg atctgggagt cggagtagac tttaaggttt atgatacctc
     4141 accagatacc gcaacaccat tgacagagat atagaaagaa cgctgagaag gtgttctttt
     4201 tatattgact gaacacctaa aaagtaatac aatggtgtta ccattaaaaa agggagcaca
     4261 aaagatgact actattacat taaaagtttc tgaagctgat aaaacattta tgaaagcaat
     4321 ggctaagttt gaaggagttt ccctttcgga acttattcgc accaaaactc ttgaagccct
     4381 agaagatgaa tacgatgctc gtgtggcaga tttagcctat caagagtatt tagaagactt
     4441 ggaaaaagga gttgaaccca ttacttggga agaaatgatg catgatttag gcttgaagga
     4501 tgaataattt gtataaatta gttccaacaa gacgtttcat caagcaattg aaaaaattgg
     4561 accgttatac gcagaagcta attacaaact atttacaaat caatgttttg gaagacccaa
     4621 gacgacacgg aaaggctttg gttggtaatc gcgttggtca atggcgctat agaattggta
     4681 attatcgagt tatcgtacaa attgtagatg atgaattagt tgttgctact ctagaagttg
     4741 gtcatcggag agatatttat tgaattaaag ctgagtaata acaatataga aagtaaggag
     4801 agtaaaaatt tgaagaaaaa atggtttttt gcagattatt atgatacaac aattatttta
     4861 cttgctttaa tctctgttat tctggtatta cttggatttg ctgagatgat tgatttggac
     4921 aatccgcctt atagtattat tgatttagta atctggggtg tttttgtaat tgattatagt
     4981 tggcgctttt ttattactaa aagaaaatgg cgctttattc ttgaaaatgt ttttgattta
     5041 ttggctattc tccctttaaa tgctattttc acagtttttc gattagggcg tatctttcgt
     5101 ttagttaaac taacaaaatt actgaaactg actcgtttac ttagaataat tggacttaca
     5161 ggtaaattag aaagaaaaat tagtagattc ttacggacaa atggcctgat ttatatctta
     5221 tatgttaata tctttattat tctagtagga agttcaattt tatctgtagt tgaagaaaaa
     5281 tccttctcag atagtctttg ttgggctctt gtgacagtaa ctactgttgg ttatggtgat
     5341 attgttccag tttccctttt ggggaaatgg ctagcagttt tactgatgct tgtcggtatt
     5401 ggaacaatag ggatgttaac aagtgctttg acgaactttt ttgtaaagga taatccagat
     5461 gaacagataa aacttgataa actccaagat gaattatcta gtccgagaat attactagag
     5521 aaacaatcta aaaagataga agaactacat aaaatgatac aagatttgat tgaaaaaaca
     5581 taataaaaat aaagatgaga aaaagtttga actgaggaga aatcaagtaa gttttgacac
     5641 aatagaacgc atattatcag gtataaaaac ttgataatat gcgttttatt gtgggaagat
     5701 gtataatgga ttgaaataag atatgaacaa atcgattagg aatttaaagc attttataac
     5761 aacgttttag agtaacgggg tactatttca tataatacag gaaaaaacaa ctccctgatg
     5821 attcaaggag ttgtctatag ttaaattagt ttttagaagc ttcttggaat tctggatttt
     5881 tccatgcttc gtcaataata gcttgcaatt ctttagcaga tgcttgcatt ttttgagttt
     5941 ctgcatcgtt caatggaatg tttactggac gaacgatacc atgtgcacca acaacagctg
     6001 gttgaccgat aaagacattc tcaactccgt attgaccttc ttggaatact gaaagtggaa
     6061 gtactgcgtt ttcatcgtca aggattgctt tagtgatacg agcaagggct actgcgatac
     6121 cgtagtatgt tgcacctttt ttgttgatga ttgtgtaggc tgcatcacga acaccttcga
     6181 acaattcaat caattcagct tcttgaacat tttgagtgtc tttaagaaat tcttcaaggt
     6241 ttacaccagc gatgttagcg tgtgaccaaa cagcgaactc agagtcaccg tgttcaccca
     6301 tgatgtaggc gtgcactgaa cgagcatcca catccaattt ttcagcaagt gcttgacgga
     6361 aacgagctga gtcaagtgaa gtacctgaac cgataacgcg ttctttaggg aaaccagaga
     6421 atttccaagt tgagtaagtc aaaacgtcaa ctgggttagc agcaacaagg aagatacctt
     6481 tgaaaccaga ttcaacaact tgagttacga ttgatttgtt gatagcaagg tttttaccta
     6541 caaggtcaag acgagtttca cctggttttt gaggtgcacc tgcagtgatc acaacaaggt
     6601 cagcgtctgc acagtcagag tattgagctg catagatttt tttaggtgaa gtgaaggcaa
     6661 gggcgtgact aaggtcaagc gcatcaccaa cagctttttc atgcaattgt ggaatttcga
     6721 taattccaag ctcttgtgca attccttggt taacaagtgc aaaagcgtaa gatgaaccta
     6781 cagcaccatc accgacaagg ataacttttt tgtgttgttt agttgaagtc attgttttaa
     6841 acatctcctt aattttatta ggggattttc cctagacaac ttcattctat cacttttaaa
     6901 aaactttgtc acgaatatgc cttatagttc tcgatgtaaa cgttttagtg gtttagaggc
     6961 tgaaatagat gggaatttat ggtataatgt tgttacttac taattgtgaa atgaggcatt
     7021 tattaatgca ggataaaaat ttagtgaatg tcaatctgac aaaggagatg aaggcaagtt
     7081 ttatcgacta cgccatgagt gttatcgtag cgcgagctct tcctgatgtt cgagatggct
     7141 taaaacctgt tcaccgtcgc attctctacg gaatgaatga attgggtgtg accccagaca
     7201 aaccccataa aaaatctgct cgtattacag gggatgtcat gggtaaatat cacccacacg
     7261 gggattcctc tatttatgaa gccatggtcc gtatggctca atggtggagc taccgttaca
     7321 tgcttgtaga tggtcatggg aattttggtt ccatggatgg agatagtgct gccgctcaac
     7381 gttataccga ggcacgtatg agcaagattg ctctggaaat gcttcgtgat atcaacaaaa
     7441 atacagttga tttcgttgat aactatgatg ccaatgaacg ggaacccttg gtcttgccag
     7501 cgcgttttcc aaaccttttg gttaatggag caactggtat cgcggttggg atggcaacca
     7561 atattccacc tcataatctg ggtgaaacca ttgatgcagt gaagttggtc atggataatc
     7621 ctgaagtgac taccaaggac ttgatggaag tcttgcctgg accagatttt ccaactggtg
     7681 ctcttgtcat ggggaaatca ggtatccata aggcttatga aacaggtaaa ggttcgattg
     7741 tcctacgttc tcgtacagag attgaaacga ctaagactgg tcgtgagcgt atcgttgtaa
     7801 cagaatttcc ttacatggtc aataaaacca aggtgcatga gcatattgtt cgcttggttc
     7861 aggaaaaacg cattgagggt atcacagcag tacgtgatga gtcaaaccgt gaaggtgttc
     7921 gatttgttat tgaagtcaag cgcgacgcct cagccaatgt tattctcaat aacctcttca
     7981 aaatgaccca aatgcaaacc aattttggtt tcaatatgct cgctatccaa aatggtatac
     8041 cgaaaatttt gtctcttcgt cagattttgg atgcttatat cgagcaccaa aaagaagtgg
     8101 ttgttcgtcg tacacgtttt gataaggaaa aagcggaagc gcgcgctcat atcttagaag
     8161 gtctcttgat tgcgctagac catatcgacg aagtgattcg tatcatccgt gctagtgaaa
     8221 cggatgcgga agctcaagct gagttgatga gcaagtttaa gctttctgaa cgtcaaagtc
     8281 aagctatcct tgatatgcgt cttcgtcgtt tgacaggttt ggaacgcgat aagattcaat
     8341 ctgagtatga tgacctcttg gctctgattg cggatttagc agatattctt gctaagcctg
     8401 aacgtgtttc tcaaattatc aaagacgaat tggatgaagt taaacgtaaa ttttctgata
     8461 agcgccgtac agagttgatg attggacagg tcttgagtct cgaggatgag gacttgattg
     8521 aagaatcgga tgtcttgatt accctttcta acagaggcta cattaagcgt ttggatcagg
     8581 acgagttcac tgctcaaaaa cgtgggggtc gtggtgtcca aggaacggga gtgaaagatg
     8641 atgactttgt tcgtgagtta gtgtcaacta gcacccatga tcatctgctc ttcttcacaa
     8701 acaagggacg tgtctatcgt cttaaaggtt atgaaattcc tgagtatggt cggactgcca
     8761 aagggctacc agtagtcaat ctcttgaaat tggatgaaga cgaaagtatt cagacggtta
     8821 tcaatgttga gtctgatcgc agtgatgatg cttatctctt ctttacaacc cgtcacggta
     8881 ttgtgaagag aaccagtgtt aaggagtttg ccaatattcg tcaaaatggt ctcaaagcgc
     8941 tgaatttaaa ggatgaagat gagttaatca atgtcttgtt ggcagaagga gatatggata
     9001 ttatcattgg taccaagttt ggttatgcag ttcgctttaa tcaatcagcc gttcgtggta
     9061 tgagtcgtat cgccactggt gtgaaaggtg ttaaccttcg tgaaggagac acagttgttg
     9121 gtgccagctt gattactgat caagatgagg ttcttattat cacagaaaaa ggatatggta
     9181 agcgtacagt cgctactgaa tacccaacaa aaggtcgtgg tggtaaggga atgcagacag
     9241 ctaaaattac cgaaaaaaat ggcttgctgg ccggtcttat gactgttcaa ggggatgagg
     9301 atttgatgat tatcactgat acaggtgtca tgattcgaac caatcttgcc aatatttcac
     9361 aaacaggacg tgcaactatg ggagttaaag taatgcgcct ggatcaagat gctcagatag
     9421 tgactttcac aacggttgcg gtggcagaaa aagaagaagt tgggacagaa aacgaaacag
     9481 aaggtgaagc ataatgtctc aaaaaaataa taaaaagaaa aacaagcgaa aaaatctgct
     9541 gacaaatatc ctagcaggat ttctgatatt actgtcactg gctttgattt ttaatactca
     9601 aattcgaaat attttcatag tctggaatac caataagtat caagttagcc aggtatcaaa
     9661 agaaaaatta gaagaaaatc aggatacaga aggcaatttt gactttgatt ctgtcaaagc
     9721 tatctcttcg gaagctgttc taacttctca atgggatgct caaaaattac cagttattgg
     9781 gggaattgca attcctgaat tggaaatgaa tttgccgatt tttaaaggac ttgataatgt
     9841 taatctcttc tacggagctg gtacaatgaa acgcgagcaa gtaatgggag aaggaaatta
     9901 tagtctagct agtcaccata tctttggtgt tgataatgct aataaaatgt tattttctcc
     9961 tttagataat gctaaaaatg gcatgaagat ttatctaacc gataaaaata aagtttatac
    10021 ttatgaaata cgtgaagtca aacgtgtgac accggatcgt gttgatgaag ttgatgatag
    10081 agatggggtc aatgaaatca cattagtaac ctgtgaagac cttgctgcta cagaacgtat
    10141 tattgtcaaa ggtgatttga aagaaacaaa agattattca caaacatcta atgaaatcct
    10201 aacagctttc aatcaaccat ataaacaatt ttattaatac aaatcagtga aatccatgat
    10261 ttcactgatt ttttaagatt ttcata
//
LOCUS       DBEJAU010000062         9786 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC323 isolate 683620
            SAMN38261939-rid24807223.denovo.062, whole genome shotgun sequence.
ACCESSION   DBEJAU010000062 DBEJAU010000000
VERSION     DBEJAU010000062.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261939
            Sequence Read Archive: SRR26833919
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 9786)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9786)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576303.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576303.1
            Genome Coverage       :: 154x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/19/2025 01:05:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,121
            CDSs (total)                      :: 2,078
            Genes (coding)                    :: 1,943
            CDSs (with protein)               :: 1,943
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 36
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 72 of 135
            Pseudo Genes (incomplete)         :: 63 of 135
            Pseudo Genes (internal stop)      :: 51 of 135
            Pseudo Genes (multiple problems)  :: 46 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9786
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261939-rid24807223.denovo.062"
                     /strain="GPSC323"
                     /isolate="683620"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            454..1497
                     /locus_tag="ACL29Z_001843"
     CDS             454..1497
                     /locus_tag="ACL29Z_001843"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF389 domain-containing protein"
                     /protein_id="HGR0070103.1"
                     /translation="MTNNKLYSLIEFRNKIYEELELSRSDLAILLCAMLIASIGLNMD
                     STPVIIGAMLISPLMTPILGVGLSLAIFDFKLLRKSFKILAIQILASLIASTLYFYLS
                     PISYASSEIVARTSPTIWDVLIAFVGGIAGIIGARKKETNNIVPGVAIATALMPPLCT
                     VGYAIASANPKFIIGSSYLFLINCSFIVIATYIGVRLMMVKKHYFKDNEEDSKMRRIL
                     LLVAVLLMIPSFISATTLVRETLKKESLKKFISEQFQGYNILKKTYSKKTHILKLTIS
                     GNYLTEEELDMISSKRGDYGLSDVSVQVSQLSDSEQLSKEELVEYFFQYIKDKEAKEK
                     EKANKFDTESEEQ"
     gene            1664..3751
                     /gene="topA"
                     /locus_tag="ACL29Z_001844"
     CDS             1664..3751
                     /gene="topA"
                     /locus_tag="ACL29Z_001844"
                     /EC_number="5.6.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000179642.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003917 - DNA topoisomerase type I (single
                     strand cut, ATP-independent) activity [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA];
                     GO_process: GO:0006265 - DNA topological change [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type I DNA topoisomerase"
                     /protein_id="HGR0070104.1"
                     /translation="MATATKKKKSTVKKNLVIVESPAKAKTIEKYLGRNYKVLASVGH
                     IRDLKKSSMSVDIENNYEPQYINIRGKGPLINDLKKEAKKANKVFLASDPDREGEAIS
                     WHLAHILNLDENDANRVVFNEITKDAVKNAFKEPRKIDMDLVDAQQARRILDRLVGYS
                     ISPILWKKVKKGLSAGRVQSIALKLIIDRENEINAFQPEEYWTVDAVFKKGTKQFHAS
                     FYGVDGKKMKLTSNNEVKEVLSRLTSKDFSVDQVDKKERKRNAPLPYTTSSMQMDAAN
                     KINFRTRKTMMVAQQLYEGINIGSGVQGLITYMRTDSTRISPVAQNEAASFITDRFGS
                     KYSKHGSKVKNASGAQDAHEAIRPSSVFNTPESIAKYLDKDQLKLYTLIWNRFVASQM
                     TAAVFDTMAVKLSQKGVQFAANGSQVKFDGYLAIYNDSDKNKMLPDMAVGDVVKQVNS
                     KPEQHFTQPPARYSEATLIKTLEENGVGRPSTYAPTIETIQKRYYVRLAAKRFEPTEL
                     GEIVNKLIVEYFPDIVNVTFTAEMEGKLDDVEVGKEQWRRVIDAFYKPFSKEVAKAEE
                     EMEKIQIKDEPAGFDCEVCGSPMVIKLGRFGKFYACSNFPDCRHTQAIVKEIGVECPS
                     CHQGQIIERKTKRNRLFYGCNRYPECEFTSWDKPVGRDCPKCGNFLMEKKVRGGGKQV
                     VCSKGDYEEEKIK"
     gene            3972..4331
                     /locus_tag="ACL29Z_001845"
     CDS             3972..4331
                     /locus_tag="ACL29Z_001845"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004258004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YbaN family protein"
                     /protein_id="HGR0070105.1"
                     /translation="MRIIYLIIGFLSLTLAIVGVVLPLLPTTPFLLLSIACFSRSSKR
                     FEDWLYHTKLYQAYVADFRETKSIARERKKKIIVSIYVLMGISIYFAPLLPVKIGLGA
                     LTIFITYYLFKVIPDKE"
     gene            4424..5056
                     /locus_tag="ACL29Z_001846"
     CDS             4424..5056
                     /locus_tag="ACL29Z_001846"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000638771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005507 - copper ion binding [Evidence
                     IEA];
                     GO_process: GO:0055070 - copper ion homeostasis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="copper homeostasis protein CutC"
                     /protein_id="HGR0070106.1"
                     /translation="MIYEFCAENVTLLEKAMQAGARRIELCDNLAVGGTTPSYGVTKA
                     AVELAANYDTTIMTMIRPRGGDFVYNDLEIAIMLEDIRLTAQAGSQGVVFGALTADKK
                     LDKPNLEKLIAASKGMEIVFHMAFDELSDEDQPEAIDWLSQAGVTRILTRAGVSGDSL
                     EKRFVHYHRILEYAKGKIEILPGGGIDLENRQTFIDQVGVTQLHGTKVVF"
     gene            5100..5756
                     /locus_tag="ACL29Z_001847"
     CDS             5100..5756
                     /locus_tag="ACL29Z_001847"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000461593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MmcQ/YjbR family DNA-binding protein"
                     /protein_id="HGR0070107.1"
                     /translation="MFEIFKSYQFNQEKAHDYGFIENSEVWTYSCQILQGDFVMTVSI
                     TADNVNFQVFDQETGDLYPHVHMESMRGSFVGNVREACLEILYQIRKACFDVQDFICH
                     QTKRIMTQVQEKYGNQLEYLWEKSPDTAVLRHEGNQKWYAVLMKISWNKLEKGREGQV
                     EAVNLKHDQVANLLSQKGIYPAFHMSKRYWISVSLDDTLSDEEVLELIEKSWNLTSKK
                     "
     gene            5826..6869
                     /locus_tag="ACL29Z_001848"
                     /pseudo
     CDS             5826..6869
                     /locus_tag="ACL29Z_001848"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001261078.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_function: GO:0003852 - 2-isopropylmalate synthase
                     activity [Evidence IEA];
                     GO_process: GO:0009098 - L-leucine biosynthetic process
                     [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-isopropylmalate synthase regulatory
                     domain-containing protein"
     gene            6881..7918
                     /gene="leuB"
                     /locus_tag="ACL29Z_001849"
     CDS             6881..7918
                     /gene="leuB"
                     /locus_tag="ACL29Z_001849"
                     /EC_number="1.1.1.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003862 - 3-isopropylmalate dehydrogenase
                     activity [Evidence IEA];
                     GO_process: GO:0009098 - L-leucine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="3-isopropylmalate dehydrogenase"
                     /protein_id="HGR0070108.1"
                     /translation="MAKKIVALVGDGIGPEIMEAGLEVLEALAEKTGFDYEIDRRPFG
                     GADIDAAGPPLPDETLKASREADAILLAAIGSPQYDGAAVRPEQGLMALRKELNLYAN
                     IRPVKIFDSLKYLSPLKPERISGVDFVVVRELTGEIYFGDHILEERKARDINDYSYEE
                     VERIIRKAFEIARNRRKIVTSIDKQNVLATSKLWRKVAEEVAQDFPDVTLEHQLVDSA
                     AMLMITNPAKFDVIVTENLFGDILSDESSVLSGTLEVMPSASHSENGPSLYEPIHGSA
                     PDIAGQGIANPTSMILSVAMMLRDSFGRYEDAERIKRAVETSLAAGILTRDIGGQAST
                     KEMTEAIIARL"
     gene            7915..8184
                     /locus_tag="ACL29Z_001850"
     CDS             7915..8184
                     /locus_tag="ACL29Z_001850"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000762418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1294 domain-containing protein"
                     /protein_id="HGR0070109.1"
                     /translation="MKLDEKITLVLLIWNVIIFLIYGIDKFKARRRAWRIQEKILLIL
                     ALTCGGFGAWLAGITFHHKTRKWYFKTVWFLGMVTTLVALYYIWR"
     gene            8188..8547
                     /gene="leuD"
                     /locus_tag="ACL29Z_001851"
     CDS             8188..8547
                     /gene="leuD"
                     /locus_tag="ACL29Z_001851"
                     /EC_number="4.2.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009316 - 3-isopropylmalate dehydratase
                     complex [Evidence IEA];
                     GO_function: GO:0003861 - 3-isopropylmalate dehydratase
                     activity [Evidence IEA];
                     GO_process: GO:0009098 - L-leucine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="3-isopropylmalate dehydratase small subunit"
                     /protein_id="HGR0070110.1"
                     /translation="MAGSSREHAAWALADYGFKVVIAGSFGDIHYNNELNNGMLPIVQ
                     PREVREKLAQLKPTDQVTVDLEQQKIISPVEEFTFEIDSKWKHKLLNSLDDIGITLQY
                     EELIAAYEKQRPAYWQD"
     gene            8677..9331
                     /locus_tag="ACL29Z_001852"
                     /pseudo
     CDS             8677..9331
                     /locus_tag="ACL29Z_001852"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002276310.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_function: GO:0003725 - double-stranded RNA binding
                     [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="Sua5/YciO/YrdC/YwlC family protein"
     gene            9495..>9786
                     /locus_tag="ACL29Z_001853"
     CDS             9495..>9786
                     /locus_tag="ACL29Z_001853"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001042398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0070111.1"
                     /translation="MNKRKVSLEDFYKWYSLNKEELLNKATVGEKFNDKLKEEFLQEW
                     PLDRILTMSIDEYVIGKGQQNKSLCYALEKGKYKNLFLGISGGSASKFGIYWN"
BASE COUNT         3059 a         1683 c         2172 g         2872 t
ORIGIN      
        1 tttagtgtaa ttgagaaagg agaaatgatt gtgattgatg ttggctaggt tatgttcaat
       61 gattcctacc gtctcaaatc ttgtcagtaa ggaaaaataa attcttcaaa agtagagatt
      121 acaaggcttg tttaagaaag aattcaaaga ccttgacaaa taaaaataaa atggttatta
      181 taagaaatgg tctaaaatag atgatgatac ttttcgaaaa tctttttacg tcagctcagc
      241 tttgccttgc tgtgttttga gcaagctacg gttagcttcc gagtttgatt ttcatttact
      301 agaaatgaaa ctgatgagag atatcagtag acatttgagt caggatatta tggaaaatga
      361 taaaaagagc tcgtgagatt ggcatatcag actactaaag tattgagttt gttaggattt
      421 tagcgactag ttagctggga aaggaagata tttgtgacaa ataataaact gtattcgttg
      481 atagaattta gaaataaaat atatgaagaa ttagaacttt ccagaagtga tttagcgatt
      541 ttactatgtg ccatgcttat cgcctctatc ggattaaata tggattcgac tcccgtgatt
      601 attggagcca tgttaatctc tcctttgatg acacctattc tgggagtggg gctctctcta
      661 gctatatttg attttaaatt gttaagaaaa tcttttaaaa tattagctat tcaaattctt
      721 gccagtctaa tagcttcaac actttatttt tatctttctc ccatttcgta tgctagttcg
      781 gagattgttg ctagaacctc tccgactatt tgggatgttc tcattgcttt tgtaggaggg
      841 atagcaggta ttattggtgc taggaaaaaa gagaccaata atattgttcc tggtgttgct
      901 attgcaaccg ccttgatgcc tcctctttgt acagtaggtt atgctattgc ttctgctaat
      961 ccaaaattta tcataggctc ctcttaccta ttcctcatca attgtagctt tattgtcatt
     1021 gcgacttata taggtgttag gttgatgatg gttaagaaac attattttaa agataatgaa
     1081 gaagactcta aaatgcgtag gattttgctt ctagttgctg ttttgctgat gattccgagt
     1141 ttcatctctg caacgacttt agtgagagaa acgttgaaaa aagagtccct taagaaattt
     1201 atatcagagc agtttcaggg gtataatatt ttgaaaaaaa cctattctaa aaagactcat
     1261 atcctaaagc taaccatttc aggaaattat ttgacagaag aagaactcga tatgatttca
     1321 agtaagagag gtgactatgg tttaagtgat gtttctgttc aagtttcaca attgtctgat
     1381 tcagaacaac ttagtaagga agagctggtg gagtatttct tccagtatat caaggataag
     1441 gaagcaaaag aaaaggagaa agccaataaa tttgatacag agtctgagga gcaataattt
     1501 cttgagaata gctggtttct ctcgtgagtc ttctatgtat atcaaaggaa gactgaggtt
     1561 ttaagtataa aacttttctt ctattatagt agctaagtct tgacagggtt caaaaaatgg
     1621 tttacacttt ataaagttta ttactttgaa aaggtgtgat actgtggcta cggcaacaaa
     1681 aaagaaaaaa tcaacagtta aaaaaaatct agtcatcgtg gagtcgcctg ctaaggccaa
     1741 gacgattgaa aaatatctag gcagaaacta caaggtttta gccagtgtcg ggcatatccg
     1801 tgatttgaag aaatccagta tgtccgtcga tattgaaaat aattatgaac cgcaatatat
     1861 caatatccga ggaaaaggcc ctcttatcaa tgacttgaaa aaagaagcta aaaaagctaa
     1921 taaagttttt ctcgcgagtg acccggaccg tgaaggagaa gcgatttctt ggcatttggc
     1981 ccatattctc aacttggatg aaaatgatgc caaccgtgtg gtcttcaatg aaatcaccaa
     2041 ggatgcagtc aaaaatgctt ttaaagaacc tcgtaagatc gatatggact tggtcgatgc
     2101 ccaacaagct cgtcggatct tggatcgctt ggtagggtat tcgatttcgc ctattttgtg
     2161 gaagaaggtc aagaagggct tgtcagcagg tcgcgttcag tccattgccc ttaaactcat
     2221 tattgaccgt gaaaatgaaa tcaatgcctt ccagccagaa gaatactgga cagttgatgc
     2281 tgtctttaaa aagggaacca aacaatttca tgcttccttc tatggagtag atggtaaaaa
     2341 gatgaaactg accagcaata acgaagtcaa ggaagtcttg tctcgtctga cgagtaaaga
     2401 cttttcagta gatcaggtgg ataagaaaga gcgtaagcgc aatgctcctt taccctatac
     2461 cacttcatct atgcagatgg atgctgccaa taaaatcaat ttccgtactc gaaaaaccat
     2521 gatggttgcc caacagctct atgaaggaat taatatcggt tctggtgttc aaggtttgat
     2581 tacctatatg cgtaccgatt cgactcgtat cagtcctgta gcgcaaaatg aggcggcaag
     2641 cttcattacg gatcgttttg gtagcaagta ttctaagcac ggtagcaagg tcaaaaacgc
     2701 atcaggtgct caggatgccc atgaggctat tcgtccgtca agtgtcttta atacaccaga
     2761 aagcatcgct aagtatctgg acaaggatca gcttaagcta tataccctta tctggaatcg
     2821 ttttgtagct agccagatga cagcggccgt ttttgatacc atggctgtta aattgtctca
     2881 aaaaggggtt caatttgctg ccaatggtag tcaggttaag tttgatggtt atcttgccat
     2941 ttataatgat tctgacaaga ataaaatgct accagatatg gctgttggag atgtggtcaa
     3001 acaggttaat agcaaaccag agcaacattt cacccaaccg cctgcccgtt attctgaagc
     3061 aacactgatt aaaaccttag aggaaaatgg ggttggacgt ccatcaacct atgcgccaac
     3121 cattgaaacc attcagaaac gttattatgt tcgcctggca gccaaacgtt ttgaaccgac
     3181 agagttggga gaaattgtca ataagctcat cgttgaatat ttcccagata tcgtaaacgt
     3241 gaccttcaca gctgaaatgg aaggtaaact ggatgatgtc gaagttggaa aagagcagtg
     3301 gcgacgggtc attgatgcct tttacaaacc attctctaaa gaagttgcca aggctgaaga
     3361 agaaatggaa aaaatccaga ttaaggatga accagctgga tttgactgtg aagtgtgtgg
     3421 cagtccaatg gtcattaaac ttggtcgttt tggtaaattc tacgcttgta gcaatttccc
     3481 agattgccgt catacccaag caatcgtgaa agagattggt gttgagtgtc caagctgtca
     3541 tcagggacaa attattgagc gaaaaaccaa gcgtaatcgc ctattctatg gttgcaatcg
     3601 ctatccagaa tgtgaattta cctcttggga caagcctgtt ggtcgtgact gtccaaaatg
     3661 tggcaacttc ctcatggaga aaaaagtccg tggtggtggc aagcaggttg tttgtagcaa
     3721 aggcgactac gaggaagaaa agattaaata agaggagggg cccgaaagta aatttcaggc
     3781 tcattttggt tagaacttga caaaatacat cattttatgc gaaactagaa gaagattatt
     3841 ttatactcaa tgagaatcaa agagcaaatt agaaagctag tcgcaggttg ctcaaagcac
     3901 tactttgagg ttgaagatgg aagctgacct ggtttgaaga gattttcgaa gagtattaac
     3961 taggagaagt tatgcgtatt atctatctaa ttattggttt tttatcgctg accttggcta
     4021 ttgttggggt tgttttaccc ttgttgccta caacaccttt ccttttgttg tctattgctt
     4081 gtttctccag aagttccaag cgattcgaag attggcttta tcataccaag ctctatcaag
     4141 catatgtagc tgattttcgt gagaccaagt ctattgcgcg tgaacgaaag aaaaaaatca
     4201 tcgtctctat ctacgtcttg atgggaattt ctatttattt tgcacctctt ttaccagtca
     4261 aaatcggtct gggtgctttg accatcttta ttacttatta tctcttcaag gtcattccag
     4321 acaaagaata gttaaaacag tagttatttg ccttgataaa attgaaagca tattcataac
     4381 aatatgatat aataaaattg aagtaatatt caaggagaat caaatgattt acgaattttg
     4441 tgctgaaaat gtgactttac ttgaaaaagc gatgcaggct ggagctcgtc ggattgaact
     4501 ctgtgataat ctagcagttg gtgggacaac acccagctat ggagtgacta aggcagcggt
     4561 tgaactggca gctaactacg atacaaccat catgaccatg attcggccac gtggtggtga
     4621 ctttgtctat aatgacctag aaattgctat catgctagaa gacattcgtt tgactgctca
     4681 ggctggaagt caaggggttg tatttggagc tttaactgct gataaaaagt tggataagcc
     4741 taatctggaa aagttaattg ctgcatcaaa aggaatggaa attgtctttc acatggcctt
     4801 tgatgaacta agtgatgaag atcaaccgga agctattgac tggctcagtc aagccggtgt
     4861 cactcgtatc ctaactcgtg ctggtgtgtc tggcgactcc ttagaaaaac gttttgttca
     4921 ctatcacaga attttggagt acgctaaagg taaaattgaa attctaccag gtggggggat
     4981 tgaccttgaa aaccgtcaaa cctttatcga ccaggtgggg gtaacacaat tgcatggtac
     5041 taaggttgtt ttttaaaaaa tagaaaggaa ctgctagctt tgggtagcag ttttcactta
     5101 tgtttgaaat ttttaaatcc tatcaattta atcaagaaaa ggctcatgat tatggtttta
     5161 tagaaaatag cgaagtctgg acatatagtt gccagatttt gcaaggtgac tttgtcatga
     5221 ctgtgtccat cactgctgat aatgtgaact ttcaagtctt tgaccaagag actggtgacc
     5281 tctatcctca cgttcatatg gaaagcatga ggggaagttt tgtcggaaat gtccgtgagg
     5341 cttgtctgga gattctttac cagattcgga aggcttgttt tgatgtgcaa gattttatct
     5401 gtcatcagac taagcgtatc atgactcaag ttcaggaaaa gtatggaaac cagttggagt
     5461 atctgtggga aaaatcgcct gatacagctg tattgcgcca tgaaggcaat caaaagtggt
     5521 atgccgtctt gatgaaaatc tcttggaata agctggaaaa gggcagagaa ggacaagtgg
     5581 aagcagtcaa cctcaagcat gaccaagtag ctaatttgct ttcacaaaag gggatttatc
     5641 cagccttcca tatgagcaag cgctactgga ttagtgtgtc tcttgatgat actttatcag
     5701 atgaagaagt actggaattg atagaaaaaa gttggaactt aacctctaaa aaatgaaata
     5761 ttttaataat tttcatgaac tttcaattag ctaaatattc tttactgaag agatttttag
     5821 aaaatatagg atttaccaca ctagaggaat atggtgccat cttcaaatac ctgattgaga
     5881 atgtcaagac ggatcgtcag atcatctatt cgcctcactg tcatgatgac ctcggaatgg
     5941 cagtggcaaa tagccttgct gctgtcaaga atggtgcagg acgtgttgaa gggactatca
     6001 atggtattag ggagcgagct gaaaatgctg ctttggaaga aattgcagtg gctctcaata
     6061 ttcgccaaga ttactaccaa gtagaaacca gtattgtcct aaatgagacc atcaatacgt
     6121 cagaaatggt ttctcgcttc tctggtattc cagttcctaa aaacaaagcc gtcgttggtg
     6181 gcaatacctt ctcccacgaa tctggtattc accaagatgg agtccttaaa aatcctctca
     6241 cttatgagat catcacacct gaattggttg gtgttaagat tccgcttgga aaattatctg
     6301 gtcgccatgc ttttgttgag aaactgagag aattggccct agattttaca gaagaggata
     6361 tcaaaccact ctttgctaag ttcaaggcac tggccgataa gaagtaagaa atcacagatg
     6421 cagatcctcg agctttggta gctggaacca tggttgaaaa tccagaaggc ttccactttg
     6481 atgatttaca acttcaaact catgcagata atgacattga agcgctcgtt agcctagcca
     6541 atatggatgg tgagaaagtc gaatttaatg cgacagggca aggttccgtt gaagcaatct
     6601 ttaacgctat cgataagttc tttaaccaat ctgttcgttt ggtgtcctac actatcaatg
     6661 cggtaacaga tggaatcgat gcccaggatc gggttttggt cactgttgaa aacagagata
     6721 cagaaaccat ctttaatgca gcagggcttg attttgatgt gttgaaggct tctgctattg
     6781 cctatataaa cgctaatacc tttgttcaaa aagagaatgc aggtgagatg ggacgcagtg
     6841 tttcttacca cgatatgcct agtgtgtaaa ggagaaggct atggcaaaga aaatagtagc
     6901 tctagtagga gacggaattg gcccagaaat catggaggct ggtttagaag ttctggaggc
     6961 tctagctgaa aaaacaggtt ttgactatga gattgacaga cgaccgttcg gaggtgcaga
     7021 tattgatgca gcaggacctc ccttacctga tgaaaccctc aaggcaagta gggaagcaga
     7081 tgctatccta ctagcagcta tcggtagtcc tcagtatgat ggagcagcgg ttcgccctga
     7141 acaaggcctg atggctctcc gtaaggaact caatctttac gctaatattc gtcctgtaaa
     7201 aatctttgac agtctcaagt atttgtcacc actcaaaccg gaacgaattt ctggtgtaga
     7261 ctttgtcgtg gtgcgtgaat tgacaggcga gatttacttt ggagatcata ttcttgaaga
     7321 gcgcaaagcg cgtgatatca acgactatag ctatgaggaa gtggagcgga ttattcgcaa
     7381 agcctttgaa attgcaagaa atcgcagaaa aatcgttact agtatcgata agcaaaatgt
     7441 tctagcgacc tcaaaactct ggcggaaagt agctgaggaa gtcgcacagg atttcccaga
     7501 tgtaaccttg gaacaccagc tggtagactc agctgctatg cttatgatta ccaatcctgc
     7561 taagtttgat gttattgtaa cggagaatct ttttggagat attttatctg atgaatcaag
     7621 cgtcttatct ggtacacttg aggttatgcc atcagccagt cattctgaaa atggaccaag
     7681 tctctatgaa cctattcacg gttcagcacc tgatattgca ggtcaaggaa ttgccaatcc
     7741 tacttccatg attttatcag ttgccatgat gttgagagat agtttcggac gttatgagga
     7801 tgcagagcgt atcaaacgtg ctgttgagac aagtctggcg gcaggaattt taacgagaga
     7861 tatagggggt caggcttcaa caaaggaaat gacggaagct attattgcaa ggttatgaag
     7921 ttagacgaaa aaattactct agtccttttg atttggaatg tcatcatttt cttgatttat
     7981 ggcattgaca aattcaaggc aagaagaaga gcttggcgca tccaagagaa aatcttactc
     8041 attttagccc ttacttgtgg tggttttggg gcctggttag ctggaatcac ttttcaccat
     8101 aagactcgaa aatggtactt taaaacagtt tggtttcttg ggatggtgac tacactagta
     8161 gccttatatt atatttggag gtaatagatg gcagggtctt cgagggaaca cgctgcttgg
     8221 gctctagcgg actatggttt taaggtcgtg attgcaggat ctttcggtga cattcattac
     8281 aataatgaac tcaataatgg catgttgcca atcgttcagc ctagagaggt tagagagaaa
     8341 ctagcccagc taaaaccaac cgaccaggta actgtggact tggaacaaca aaaaatcatc
     8401 tcaccagttg aagaattcac cttcgagata gatagcaagt ggaaacataa actcctaaat
     8461 agtttggatg atatcggtat taccttgcag tatgaagagt tgattgctgc ttatgaaaaa
     8521 caacgaccag cctactggca ggattagaaa aaatagaaaa ggaaatatag taaactgaaa
     8581 taagatgtaa acaaatgaat tggagcttaa catccatttc cagcaatttt ttagaaacta
     8641 cagtggacta ttctggattc aacacattat aaaattatga caaaacacat tcataagaag
     8701 gctacgacat tttaaaaggt gagggcggat gtatcgtttg ccctactaaa gttggttaca
     8761 ttatcatgac cagtgacaag gcaggacttg agcgtaagtt cgcagccaaa gaacgtaagc
     8821 gtaacaaacc aggtgttgtt ctctgcggta gcatggatga actttgcgct ttagcgcaac
     8881 tcaacccaga aattgaagca ttctactaaa aacattggga tgaagatatt cttcttggtt
     8941 gtatccttcc ttggaaacca gaagcctttg aaaaactcaa agcatacggg gatggccgtg
     9001 aagaacttat tactgatgta cgtggtacta gctgttttgt tatcaagttt ggaaaagcag
     9061 gtgaacaatt ggctgccaag ctttgggaag aaggtaaaat ggtctacgcc tcatctgctt
     9121 caatgacaaa acgattgaaa ctcgctatga gcaaggtgta atggtgtcta tggtcgataa
     9181 ggacggcaaa ctcatcccag aacaaggagg agcacgttca acttcaccag ctccagttgt
     9241 gatccgtaaa gggcttgaca ttgataaaat catgatgcac ctgtcagata cttttaactc
     9301 atgggactac cgtcaggttg agtattatta ggatagagaa gaagtctagt gttatgagat
     9361 attaaagctc ctaacactgg gcttttgttt agaatttctt ttctttttct ataggatatg
     9421 gtattctatg tagaaaatat atgttaataa gtaatgccaa tatttaaaca tcattagtaa
     9481 aaggagttag attgatgaat aaaagaaaag ttagtttaga agatttttat aaatggtata
     9541 gtctaaataa agaagagtta ttaaataagg caactgttgg tgaaaagttt aatgataaat
     9601 taaaagaaga gtttctccag gaatggcctt tggataggat tttaacaatg tcaatcgatg
     9661 aatatgtaat aggaaaggga cagcaaaata agtctttatg ctacgctctt gagaagggaa
     9721 aatacaaaaa tctatttctt ggaatttctg gtggctcagc ttcaaaattt ggtatttatt
     9781 ggaata
//
LOCUS       DBEJAU010000063         9691 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC323 isolate 683620
            SAMN38261939-rid24807223.denovo.063, whole genome shotgun sequence.
ACCESSION   DBEJAU010000063 DBEJAU010000000
VERSION     DBEJAU010000063.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261939
            Sequence Read Archive: SRR26833919
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 9691)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9691)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576303.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576303.1
            Genome Coverage       :: 154x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/19/2025 01:05:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,121
            CDSs (total)                      :: 2,078
            Genes (coding)                    :: 1,943
            CDSs (with protein)               :: 1,943
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 36
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 72 of 135
            Pseudo Genes (incomplete)         :: 63 of 135
            Pseudo Genes (internal stop)      :: 51 of 135
            Pseudo Genes (multiple problems)  :: 46 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9691
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261939-rid24807223.denovo.063"
                     /strain="GPSC323"
                     /isolate="683620"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            complement(42..1133)
                     /locus_tag="ACL29Z_001854"
     CDS             complement(42..1133)
                     /locus_tag="ACL29Z_001854"
                     /EC_number="2.1.1.37"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466327.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003886 - DNA
                     (cytosine-5-)-methyltransferase activity [Evidence IEA];
                     GO_function: GO:0008168 - methyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA];
                     GO_process: GO:0006304 - DNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA cytosine methyltransferase"
                     /protein_id="HGR0070112.1"
                     /translation="MGKIVAIDLFSGAGGTTSGLKKSGIDVQVAVEIDSVAVKTYKLN
                     NPEVSVIDKDINVVSGDEVKEYLKIDTDDKLMLVACPPCQGFSTIGTNNENDERNQLV
                     FQFLRLINELNPDFLLMENVVGMTRTRNEKIFKKFLTSIDNNYSVIYDILNTADYGVP
                     QSRKRLVLHGIRKEILDNTNLTLNLPSKTHSNIPELDLLSWINADIIMDLPPIEGGEE
                     YIGEGIYNHVANKLSNLNIERITHIRNNGGSRTSLPKSLELNCHKNRLGHSDVYGILD
                     INKPSITITGGCMSYSKGRFGHPTQNRALSAREAARLQSFDDDYIFVGNRGQLAKQIG
                     NAVPVKLAQASGNYFMSVYREIANGQSDN"
     gene            complement(1214..3865)
                     /locus_tag="ACL29Z_001855"
     CDS             complement(1214..3865)
                     /locus_tag="ACL29Z_001855"
                     /EC_number="6.1.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009732359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004812 - aminoacyl-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0004832 - valine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006438 - valyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="valine--tRNA ligase"
                     /protein_id="HGR0070113.1"
                     /translation="MSKELSSKYNPAEVEAGRYQKWLDADVFKPSGDQKAKPYSIVIP
                     PPNVTGKLHLGHAWDTTLQDIIIRQKRMQGFDTLWLPGMDHAGIATQAKVEERLRGEG
                     ITRYDLGRESFLTKVWEWKDEYATTIKEQWGKMGLSVDYSRERFTLDEGLSKAVRKVF
                     VDLYKKGWIYRGEFIINWDPAARTALSDIEVIHKDVEGAFYHMNYMLEDGSRALEVAT
                     TRPETMFGDVAVAVNPEDPRYKDLIGKNVILPIANKLIPIVGDEHADPEFGTGVVKIT
                     PAHDPNDFLVGQRHNLPQVNVMNDDGTMNELAFEFSGMDRFEARKAVVAKLEEIGALV
                     KIEKRVHSVGHSERTGVVVEPRLSTQWFVKMDQLAKNAMANQDTEDKVEFYPPRFNDT
                     FLQWMENVHDWVISRQLWWGHQIPAWYNEAGEIYVGEEAPEGDDWTQDSDVLDTWFSS
                     ALWPFSTMGWPEVDSEDFKRYFPTSTLVTGYDIIFFWVSRMIFQSLEFTGRQPFQNVL
                     IHGLIRDEQGRKMSKSLGNGIDPMDVIEKYGADALRWFLSNGSAPGQDVRFSYEKMDA
                     SWNFINKIWNISRYILMNNEGLPLEQATANVEKVATGEAGNVTDRWILHNLNETIGKA
                     TANFDKFEFGVAGHILYNFIWDEFADWYVELTKEVLYSDNEEEKVITRSVLLYTLDKI
                     LRLLHPIMPFVTEEIFGQISEGSIVTAAYPTVNLAFEDLAAHTGVESLKNLIRAVRNA
                     RAEVNVAQSKPITILVKTSDSDLEAFFNSNVNYIKRFTNPEHLEIASTIPAPELAMSS
                     VITGAEIYLPLADLLNVEEELARLEKELAKWQKELDMVGKKLSNERFVANAKPEVVQK
                     ERDKQADYQAKYDATVARIDEMKKLVK"
     gene            complement(3858..4436)
                     /locus_tag="ACL29Z_001856"
     CDS             complement(3858..4436)
                     /locus_tag="ACL29Z_001856"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000550018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HGR0070114.1"
                     /translation="MHLFIIGAPASGKMTIGQELSRLMDSTLFYNHQAIDFALEIYQD
                     YTEEMWEFVRGITFSFLGASARNQRSVILTDVIDFSNQYHLIYFKQIQSLLDDYHQEI
                     LFVELETSLEECIRRNRTENRLKYKPLKRHIEVSEREIIETAETLQLNSQHQPNELNH
                     YFKINNTNLSAEEAAKQIQNKINKIEKGHTHV"
     gene            complement(4436..4996)
                     /locus_tag="ACL29Z_001857"
     CDS             complement(4436..4996)
                     /locus_tag="ACL29Z_001857"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000124561.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family protein"
                     /protein_id="HGR0070115.1"
                     /translation="MARTELPDKIETERLVLRVRTVADAEDIHAYASLPEVAYSAGFP
                     PVKTLEDEIYYLEHILPERNQKENLPTGYGIVVKGTDKVIGSVDFNHRYGDDVLELGY
                     TLHSDYWGRGYVPEAACALIDLAFKELGLHKIELTCFGYNLQSQRVAEKLGFTLEARI
                     RDRKDAQGNRCDDLRYALLESEWEVI"
     gene            complement(4983..5432)
                     /locus_tag="ACL29Z_001858"
     CDS             complement(4983..5432)
                     /locus_tag="ACL29Z_001858"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0010181 - FMN binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="flavin reductase"
                     /protein_id="HGR0070116.1"
                     /translation="MIGVVARENAAEQIKQYQKFTVNISDETSMLAMEQAGFISHQEK
                     LERLGVHYEISERTQTPILDACPLVLDCRVDRIVEEDGICHIFAKILERLVAPELLDE
                     KRHFKNQLFAPTYFMGDGYQRVYRYLDKRVDMKGSFIKKARKKDGKN"
     gene            complement(5844..6239)
                     /locus_tag="ACL29Z_001859"
     CDS             complement(5844..6239)
                     /locus_tag="ACL29Z_001859"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000038635.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-hairpin-helix domain-containing protein"
                     /protein_id="HGR0070117.1"
                     /translation="MSKKLNRKKQLRNGLRRAGAFSSTVTKVVDETKKVVKRAEQSAS
                     AAGKAVSKKVEQAVEATKEQAQKVANSVEDFAANLGGLPLDRAKTFYDEGIKSASDFK
                     NWTEKELLDLKGIGPATIKKLKENGIKFK"
     gene            complement(6335..6589)
                     /locus_tag="ACL29Z_001860"
     CDS             complement(6335..6589)
                     /locus_tag="ACL29Z_001860"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000119704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1912 family protein"
                     /protein_id="HGR0070118.1"
                     /translation="MSYEQEFMKEFEAWVNTQIMINDMAHKESQKVYEEDQDERAKDA
                     MIRYESRLDAYQFLLGKFENFKVGKGFHDLPEGLFGERNY"
     gene            complement(6599..7933)
                     /locus_tag="ACL29Z_001861"
     CDS             complement(6599..7933)
                     /locus_tag="ACL29Z_001861"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000752887.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF438 domain-containing protein"
                     /protein_id="HGR0070119.1"
                     /translation="MADERIHVLRDILLELHNGASPESVQERFDATFAGVSAIEISLM
                     EHELMNSDSGVTFEDVMELCDVHANLFKNAIKGVEVSDTEHPGHPVRVFKEENLALRA
                     ALIRIRRLLDTYESMEDEEMLAEMRKGLVRQMGLVGQFDIHYQRKEELFFPIMERYGH
                     DSPPKVMWGVDDQIRELFQTALTTAKSLPEVSISSVKEVFEAFAIEFESMIFKEESIL
                     LMILLESFTQDDWLQIAEESDAYGYAIIHPSEKWVPERQSFIEEKIAEEPVQLDTAEG
                     QVQQVIDTPEGHFTITFTPKEKEAVLDRHSQQAFGNGYLSVEQANLILNHLPMEITFV
                     NKEDIFQYYNDNTPADEMIFKRTPSQVGRNVELCHPPKYLDKVKAIMKGLREGTKDKY
                     EMWFKSESRGKFVHITYAAVHDENGEFQGVLEYVQDIQPYREIDTDYFRGLE"
     gene            complement(7933..8166)
                     /locus_tag="ACL29Z_001862"
     CDS             complement(7933..8166)
                     /locus_tag="ACL29Z_001862"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006144975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1858 domain-containing protein"
                     /protein_id="HGR0070120.1"
                     /translation="MDNIIDVSIPVAEVVDKYPEVLEILVELGFKPLANPLMRNTVGR
                     KVSLKQGSKLAGTPMDKIVRTLEANGYEVIGLD"
     gene            complement(8627..8809)
                     /locus_tag="ACL29Z_001863"
     CDS             complement(8627..8809)
                     /locus_tag="ACL29Z_001863"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001068155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0070121.1"
                     /translation="MNPIKAFDKIYGNYFLTVQGVKVMKTIKKDDHVVVGLGKLFIAD
                     KLMDTARWLIRPEERE"
     gene            complement(8811..9590)
                     /locus_tag="ACL29Z_001864"
     CDS             complement(8811..9590)
                     /locus_tag="ACL29Z_001864"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000840413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0070122.1"
                     /translation="MAEQDLAMQVLQQVVKLPVVKVDRSKFLVDKFSKELGPQDIPTL
                     LEQGPTPLLSQEILDRVANACIRDNVLLASGTSVLAGLPGGLAMAITIPADVAQFYGF
                     SLKLAQELGYIYGYEDLWASRDELSEDAQNTLLLYLGVMLGVNGTAALLRAGGITIAK
                     QVMKTVPNKALTKTLWYPILKKVLKIFGVNLTKGGLAKGIGKFIPILGGIIAGGLTFA
                     TMKPMGESLQKELSKLVNYSEVQYQEDVETIRKEAEIIKGE"
BASE COUNT         2760 a         2182 c         1802 g         2947 t
ORIGIN      
        1 ttttattttt aaaaaaattt ttagttattc cttctaaact ctcaattatc tgattgtcca
       61 tttgctatct ccctataaac tgacataaaa taatttccac tagcttgagc taattttact
      121 ggaactgcat taccaatttg cttagctaat tgacctctat ttccaacaaa aatatagtca
      181 tcatcaaaag actgtaatct tgcagcttct cttgcactta aagctctatt ttgagttggg
      241 tgcccaaatc taccttttga atatgacata caccctcctg taatagtaat ggaaggtttg
      301 ttgatatcta atattccata tacgtcacta tgacctaaac gatttttatg acaatttaat
      361 tctaaagatt ttggcaaaga ggttctactt cccccattat ttctaatatg agtaattctc
      421 tcaatattta aattagatag tttgtttgca acatgattgt agataccttc tccaatatat
      481 tcttcaccac cttcaatagg aggcaagtcc attattatat ccgcattaat ccatgaaaga
      541 aggtccaatt ctggtatatt tgaatgagtt ttggaaggca aattcaaagt taaattcgtg
      601 ttatcaagaa tttcttttct aattccgtgt aacaccaatc tttttctaga ttgaggaact
      661 ccataatcag ctgtatttaa aatgtcataa ataacactat aattattatc gattgatgtc
      721 aaaaattttt taaagatttt ttcatttctt gttctagtca tacccacaac attttccatt
      781 aatagaaaat caggattcaa ttcattaatc aaacgaagaa attgaaaaac aagttgattc
      841 ctctcgtcat tttcattatt agtaccaata gttgaaaaac cttgacatgg tgggcatgcc
      901 acgagcatta gtttatcgtc tgtatcaatt ttaagatact cttttacttc atctcctgat
      961 actacattta tatctttatc tattacagac acctcaggat tatttaactt ataagtttta
     1021 acagctacgg aatcaatttc aacagcaact tgaacatcta tgcctgattt tttaaggcca
     1081 cttgtagtgc cacctgcacc gctaaataaa tcaatagcaa caattttccc catagtattc
     1141 tcctaaagtt tctccttttt attataacat tatcaaatgt aaaacccaac ccgatagggt
     1201 taggttttta acatcatttc accaacttct tcatctcatc aatacgtgct acggtcgcat
     1261 catacttggc ttggtagtca gcttgtttgt cgcgttcttt ttggacgact tctggtttgg
     1321 cgttggctac gaagcgttcg ttagagagtt tcttaccaac catgtccagt tctttctgcc
     1381 atttggcaag ttctttttcc agacgtgcca attcttcttc gacattgagg agatcggcca
     1441 gtggcaggta gatttctgct cctgtgatga cacttgacat agccagttca ggtgcaggga
     1501 tggttgatgc gatttccaag tgttctggat ttgtaaagcg tttgatatag ttgacattgc
     1561 tgttaaagaa ggcttccaag tcgctatcgc ttgtcttaac aaggatggtg ataggtttgc
     1621 tttgtgctac gtttacttcc gcacgcgcat tccgaacagc acgaatcaag tttttgagac
     1681 tttccacacc agtgtgagcc gcaaggtctt caaaggctag attaacagtt gggtatgcag
     1741 ctgtcacgat agaaccttct gagatttgtc caaagatttc ctctgtcacg aatggcatga
     1801 ttgggtgaag gagacgaagg atcttgtcca gagtgtaaag gagaacagaa cgtgtgatga
     1861 ctttctcttc ttcattatcg ctataaagga cttccttggt caactcaaca taccagtccg
     1921 caaattcatc ccagatgaag ttgtagagga tgtggccagc aacaccaaac tcaaacttat
     1981 caaagttagc agttgctttt ccaatcgttt cattgaggtt gtggagaatc cagcggtccg
     2041 tcacattacc agcctcacct gttgcaactt tttcgacatt ggcagttgct tgctcaaggg
     2101 gcaaaccttc attgttcata aggatgtagc gagagatgtt ccagatcttg ttaatgaagt
     2161 tccatgaagc atccattttc tcataagaga aacgcacgtc ttgtcctggc gcagaaccgt
     2221 ttgaaaggaa ccatcgaagg gcatcggcac cgtatttctc gataacatcc attgggtcaa
     2281 tcccgttacc gagagactta gacatcttgc gtccttgctc gtcacgaata agaccgtgga
     2341 taaggacgtt ttggaatggt tgacggcctg tgaattccaa tgactggaag atcatacgag
     2401 acacccagaa gaagatgatg tcgtaacctg ttaccaaggt tgaagttggg aaataacgtt
     2461 taaagtcttc tgagtcgact tcaggccagc ccatggttga aaatggccaa agagcagaac
     2521 taaaccacgt atcaagcaca tctgaatcct gagtccagtc gtctccttct ggtgcctctt
     2581 ctcccacata aatctcacct gcctcgttgt accaagcagg gatttggtga ccccaccaga
     2641 gctgacgaga gataacccag tcgtggacat tttccatcca ttgaaggaag gtatcgttga
     2701 aacgaggtgg gtagaattcg accttgtcct ctgtgtcttg gttggccatg gcgttcttag
     2761 ccaattggtc catcttgacg aaccattgag tagacaagcg tggctcaact acgacacctg
     2821 tacgttctga gtgaccaaca ctgtggacac gtttttcgat tttgacaagg gcaccgattt
     2881 cttccaactt agcaacgact gccttacgag cttcaaaacg atccatgcct gaaaattcaa
     2941 aggcaagctc attcatagtt ccgtcgtcgt tcatgacgtt gacttgtggc aagttatgac
     3001 gttggccaac caagaagtca tttggatcgt gggcaggtgt gattttcacg acaccagtac
     3061 caaactcagg atctgcgtgc tcatctccaa cgattgggat gagtttatta gcgattggaa
     3121 ggatgacgtt tttaccaatc aagtccttgt aacgcgggtc ttctggatta accgcaaccg
     3181 caacgtcccc aaacatagtc tcaggacgag ttgtagcaac ttcaagggcg cgtgaaccat
     3241 cttccagcat gtagttcatg tggtagaagg caccttcgac atccttgtga atcacctcaa
     3301 tatcagaaag ggctgtgcga gctgctgggt cccagttgat gataaactca ccacgataga
     3361 tccagccttt cttgtaaagg tccacaaaga ccttacgaac agcttttgac aaaccttcgt
     3421 caagagtgaa acgctcacga gaatagtcta cagaaagccc catcttgccc cattgttcct
     3481 tgatggtagt ggcatattcg tctttccatt cccagacctt cgtcaagaaa gactcacgac
     3541 ctaggtcata acgcgtaata ccctcaccac gtaagcgctc ctcaacctta gcctgagtcg
     3601 caataccagc gtggtccata cctggaagcc aaagcgtatc aaagccctgc atgcgttttt
     3661 gacggatgat gatatcctgc aaagtcgtat cccaagcgtg accaaggtga agtttcccag
     3721 ttacgtttgg tggtggaatc acgattgaat aaggcttagc cttttgatcg cctgaaggct
     3781 tgaaaacatc cgcatcaagc catttttggt aacgaccagc ctcaacctcg gctggattgt
     3841 atttagatga aagttcttta gacatgtgtg tgtcctttct ctattttgtt tattttattt
     3901 tgaatctgct tagcagcttc ttctgcagac aaattcgtat tatttatttt aaagtagtgg
     3961 ttcaactcat tcggttgatg ttgggaattt aattgaagtg tttcagcggt ctctataatt
     4021 tctctttcag atacctcaat atgtcgtttt aagggtttgt actttaatcg attctccgtt
     4081 cgatttcgac gtatgcactc ttcaagactt gtttccaact caacaaaaag aatctcttga
     4141 tgataatcat ccaacaaact ctgaatttgc ttgaaatata tcagatgata ctgatttgaa
     4201 aaatcaatta catctgttaa aattactgat cgctgatttc ttgcactcgc tccaaggaat
     4261 gaaaaagtga ttccacgaac aaattcccac atttcctctg tatagtcctg atagatttct
     4321 agtgcaaaat cgatggcttg atggttataa aagagggtag aatccatcag tcgagacagt
     4381 tcttgaccaa tggtcatttt tcctgatgct ggagcaccaa tgatgaaaag atgcatcaaa
     4441 tcacctccca ctcactctcc agcaaggcat atctcaaatc atcacagcgg ttgccttgag
     4501 catctttgcg gtctcttatg cgagcttcga gggtaaagcc aagcttttcc gcgactcgtt
     4561 gactttgaag gttatatcca aagcaagtta gttcaatctt gtgaagacca agttctttaa
     4621 aagctagatc aatcaaggca cacgctgctt ctggaacata acctcgaccc cagtagtctg
     4681 agtgtaaggt atagccaagc tctagcacat cgtccccata gcggtggttg aagtcaacag
     4741 aaccaatgac tttatcggtt cctttgacga caatcccgta gcctgttggg agattttcct
     4801 tttgattacg ctccggaaga atgtgctcca gataataaat ctcatcttcc aaggtcttga
     4861 ctggaggaaa acctgctgaa taggcgacct ctggcaaact agcgtaggca tggatatcct
     4921 cagcatccgc cacagtacgg actcgtaaaa cgagacgttc tgtttcgatt ttatctggca
     4981 gctcagttct tgccatcctt cttcctcgct tttttgatga aactgccctt catatctaca
     5041 cgcttgtcca gatagcgata aacgcgctga tatccatctc ccatgaaata ggttggggca
     5101 aacagttgat ttttaaaatg tctcttttca tccaggagtt ctggggcaac aagtcgctca
     5161 agaatcttgg caaagatgtg gcaaataccg tcttcctcaa caatcctatc tacccgacaa
     5221 tctaaaacaa gtggacaggc gtctaaaata ggagtctgag ttcgttcaga aatttcataa
     5281 tgcactccca aacgttccaa tttctcctga tgactgataa aaccagcctg ctccatcgca
     5341 agcatagaag tttcatcaga aatattcaca gtaaattttt gatactgttt gatctgctct
     5401 gcggcattct ctctcgcaac gactccaatc acaacccaat ctcctagact ataagaggaa
     5461 ctacaggtcg tgatgttata gccaaaattc taatcttgat atcctaaaat aaaaacagga
     5521 aaaccataat atagtttact tgtgttaaaa gattgcttca taacaacccc ctttgactaa
     5581 gacgtaaaag aaaagccctg ccatctacat gacagggacg aatgtattta tccgcggtac
     5641 cacccaattt cgggccaagc ccgcatcttt agtctttaaa ataaaaagac agaaatattt
     5701 cattttttca gtcattagca accagttttg acacatttgt ggacttctca gcgccgccac
     5761 tttctgtaaa atgtgggatt caaaacacct ctaatggctc tattgtagca agtttttctc
     5821 ggaaatgcaa ggctcaagaa aaattacttg aacttgatgc cattttcttt caatttcttg
     5881 atggtagctg ggccgattcc tttcaagtca aggagttctt tttcagtcca gtttttgaaa
     5941 tctgaagcag acttgattcc ttcatcatag aaagtcttgg cacgatcaag tggaagtcca
     6001 cccaagtttg ctgcaaaatc ttctacagaa ttagctactt tttgagcttg ctctttggta
     6061 gcttctactg cttgttcaac ttttttagaa acagccttac cagctgcgct tgctgactgt
     6121 tctgcacgct tcacgacttt ttttgtctca tctacaacct tagtcacagt acttgaaaag
     6181 gcacctgcgc gacggagacc atttcgtaat tgttttttac gattgagttt ctttgacatg
     6241 ataaaatcct ttcaataaaa aatccctgct ctgacaagga tttaacataa acattctatc
     6301 aagattttag tgaaaaatca agaatctttc tcgtttaata attccgctca ccaaacaagc
     6361 cttctggcaa atcatggaat cccttgccta ctttgaagtt ttcaaactta ccaagcaaga
     6421 actgataagc atccaagcga ctctcatagc gaatcatggc atctttggca cgctcgtcct
     6481 ggtcttcttc gtaaactttt tggctttcct tgtgcgccat gtcgttaatc atgatttggg
     6541 tattgaccca agcttcaaat tccttcataa attcttgttc gtaactcatt ttttctcctt
     6601 attctaatcc acggaaatag tccgtatcaa tctcacggta gggctggata tcctgaacgt
     6661 attccagtac accttggaat tctccgtttt catcgtgtac tgcagcatag gtgatgtgga
     6721 caaacttgcc tcgcgactca gacttgaacc acatttcata cttgtccttg gtcccctcac
     6781 gaagtccctt catgatagcc ttgaccttgt ccaaatactt aggcggatga cagagttcga
     6841 cattgcgccc gacttgggac ggcgtccgtt tgaaaatcat ctcatcagct ggcgtattgt
     6901 cattgtaata ctggaaaata tcttctttat tgacaaaggt aatctccata gggagatgat
     6961 tgaggatgag attggcctgc tcgactgaaa gatagccatt accaaaagcc tgttgactat
     7021 ggcggtccag cacagcttcc ttttccttag gggtaaaggt aatggtaaaa tggccttctg
     7081 gcgtatctat gacttgttga acttgacctt ctgccgtatc tagctgtaca ggctcctctg
     7141 caatcttttc ctcaataaag ctctgtcgtt ctggtaccca tttctctgac ggatggatga
     7201 tggcataccc ataggcatcg ctctcctccg caatctgaag ccagtcatcc tgagtaaaag
     7261 actcaaggag aatcatgagt aggatggact cttccttgaa aatcatactt tcaaactcta
     7321 tcgcaaaagc ttcaaaaact tcctttacac tgctaattga cacttctggt agtgacttgg
     7381 ctgtcgttag agctgtttga aagagttccc taatctgatc atccactccc cacataactt
     7441 tgggaggtga atcgtgtcca tagcgctcca tgataggaaa gaagagttct tctttacgtt
     7501 ggtaatggat gtcaaattgc cccacaagtc ccatctgacg caccaagccc ttgcgcatct
     7561 ccgcaagcat ttcctcgtct tccatagact cataggtatc taacaatcta cgaatgcgaa
     7621 tcaaggccgc acggagagcc agattttctt ctttgaagac acgaactggg tgacctggat
     7681 gctcagtatc tgaaacttca acacctttga tagcattttt aaaaagattg gcatggacat
     7741 cacagagttc cataacatct tcaaaggtga cacctgagtc tgagttcatc agctcgtgct
     7801 ccataaggga aatctcaatg gctgagacac ccgcaaaggt cgcatcaaaa cgctcctgaa
     7861 ccgactcagg agaggcgcca ttatgcaatt ctaataaaat atcccgtagg acatgaatcc
     7921 gttcatctgc cattagtcta atccaatcac ttcgtagcca ttcgcttcca gtgtgcgtac
     7981 aatcttgtcc ataggagttc ctgctagctt agaaccttgt ttaagtgata ctttacgacc
     8041 aactgtattg cgcatcaagg gattggcaag gggtttaaaa cccagctcca ctagaatttc
     8101 caagacttct ggatacttgt ccaccacttc tgcaacagga attgacacat cgatgatatt
     8161 gtccatgacg acctccatta tatgttctaa tactcaatga aaatcaaaga gcaaactaga
     8221 aagctagccg caggttgctc aaaacagtgt tttgaggttg tagatagaac tgacgaagtc
     8281 agctcaaaac accgttttga ggttgtggat agaactgacg aagtcagtaa catatatact
     8341 gcaaggtgaa gctgacgtgg tttgaagaga ttttcgaaga gtataaaatg attttactgc
     8401 ttatattata ccatatggag agagattaaa aaactagcag tggagttcct gctagctctc
     8461 tgcgacttgg attaccatct agataagttt aaagagccaa tccaatatct taaataatat
     8521 cttgtaaaac agcaattgaa ctgcaaagga aatgatcatc caaaagaatt tcacaatccc
     8581 aataatcggt ttgataaaaa gaatagcaag aagaccaaaa aaaatttcat tctctctcct
     8641 ctggcctaat gagccaccga gccgtatcca ttagcttatc tgcaataaaa agttttccca
     8701 gaccaacaac gacatggtca tctttcttta tcgttttcat cacttttaca ccttgcacgg
     8761 tcaaaaagta attaccataa attttatcaa aagctttgat aggattcata ttactctcct
     8821 ttaatgattt cagcctcttt tcggattgtt tcaacatctt cttgatattg aacttcacta
     8881 tagttgacta gcttggataa ttctttctgc aagctttccc ccattggttt catagttgca
     8941 aaggttaaac cacctgcaat gataccaccc aagataggaa taaatttccc tattcctttg
     9001 gccagccctc ccttggtaag attcacacca aatattttta agactttttt caaaataggg
     9061 taccaaagcg tctttgttaa agctttatta ggtactgttt tcattacctg tttggcaatt
     9121 gttataccac cagcacgtag caaagcagca gttccattca cccccaacat gacgcctaga
     9181 taaagcaaaa gggtattttg agcatcttca ctcaactcat cgcgtgaagc ccaaagatcc
     9241 tcataaccat aaatataacc taattcttgg gccaatttca gagagaaacc ataaaattga
     9301 gccacatcag ctggaatggt aattgccata gcaagccctc caggtaatcc tgccaaaaca
     9361 gaagtcccac tcgctaataa aacattatcc ctaatacagg cattagccac tcgatctaag
     9421 atttcttgag ataagagagg cgttggacct tgttccaata aggtaggaat gtcctgtgga
     9481 cccaattctt tggaaaactt atccactaaa aatttcgaac gatcaacctt aacaactggt
     9541 agttttacca cttgttgtaa tacttgcata gctaagtctt gttcagccat atacaaactc
     9601 cttatttctt ttttacacct tatcatatta tatttcctac aaaaaaagca ttttctaatt
     9661 agataacatt aaaaaataca gaatcccttt t
//
LOCUS       DBEJAU010000064         9567 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC323 isolate 683620
            SAMN38261939-rid24807223.denovo.064, whole genome shotgun sequence.
ACCESSION   DBEJAU010000064 DBEJAU010000000
VERSION     DBEJAU010000064.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261939
            Sequence Read Archive: SRR26833919
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 9567)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9567)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576303.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576303.1
            Genome Coverage       :: 154x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/19/2025 01:05:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,121
            CDSs (total)                      :: 2,078
            Genes (coding)                    :: 1,943
            CDSs (with protein)               :: 1,943
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 36
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 72 of 135
            Pseudo Genes (incomplete)         :: 63 of 135
            Pseudo Genes (internal stop)      :: 51 of 135
            Pseudo Genes (multiple problems)  :: 46 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9567
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261939-rid24807223.denovo.064"
                     /strain="GPSC323"
                     /isolate="683620"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            285..2945
                     /gene="rrgA"
                     /locus_tag="ACL29Z_001865"
     CDS             285..2945
                     /gene="rrgA"
                     /locus_tag="ACL29Z_001865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000757844.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PI-1 pilus tip adhesin RrgA"
                     /protein_id="HGR0070123.1"
                     /translation="MKKVRKIFQKAVAGLCCISQLTAFSSIVALAETPETSPAIGKVV
                     IKETGEGGALLGDAVFELKNNTDGTTVSQRTEAQTGEAIFSNIKPGTYTLTEAQPPVG
                     YKPSTKQWTVEVEKNGRTTVQGEQVENREEALSDQYPQTGTYPDVQTPYQIIKVDGSE
                     KNGQHKALNPNPYERVIPEGTLSKRIYQVNNLDDNQYGIELTVSGKTVYEQKDKSVPL
                     DVVILLDNSNSMSNIRNKNARRAERAGEATRSLIDKITSDPENRVALVTYASTIFDGT
                     EFTVEKGVADKNGKRLNDSLFWNYDQTSFTTNTKDYSYLKLTNDKNDIVELKNKVPTE
                     AEDHDGNRLMYQFGATFTQKALMKADEILTQQARQNSQKVIFHITDGVPTMSYPINFN
                     HATFAPSYQNQLNAFFSKSPNKDGILLSDFITQATSGEHTIVRGDGQSYQMFTDKTVY
                     EKGAPAAFPVKPEKYSEMKAAGYAVIGDPINGGYIWLNWRESILAYPFNSNTAKITNH
                     GDPTRWYYNGNIAPDGYDVFTVGIGINGDPGTDEATATSFMQSISSKPENYTNVTDTT
                     KILEQLNRYFHTIVTEKKSIENGTITDPMGELIDLQLGTDGRFDPADYTLTANDGSRL
                     ENGQAVGGPQNDGGLLKNAKVLYDTTEKRIRVTGLYLGTDEKVTLTYNVRLNDEFVSN
                     KFYDTNGRTTLHPKEVEQNTVRDFPIPKIRDVRKYPEITISKEKKLGDIEFIKVNKND
                     KKPLRDAVFSLQKQHPDYPDIYGAIDQNGTYQNVRTGEDGKLTFKNLSDGKYRLFENS
                     EPAGYKPVQNKPIVAFQIVNGEVRDVTSIVPQDIPAGYEFTNDKHYITNEPIPPKREY
                     PRTGGIGMLPFYLIGCMMMGGVLLYTRKHP"
     gene            3169..5133
                     /locus_tag="ACL29Z_001866"
     CDS             3169..5133
                     /locus_tag="ACL29Z_001866"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0018262 - isopeptide cross-linking
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="isopeptide-forming domain-containing fimbrial
                     protein"
                     /protein_id="HGR0070124.1"
                     /translation="MKSINKFLTILAALLLTVSSLFSAATVFAAEQKTKTLTVHKLLM
                     TDQELDAWNSDAITTAGYDGSQNFEQFKQLQGVPQGVTEISGVAFELQSYTGPQGKEQ
                     ENLTNDAVWTAVNKGVTTETGVKFDTEVLQGTYRLVEVRKESTYVGPNGKVLTGMKAV
                     PALIILPLVNQNGVVENAHVYPKNSEDKPTATKTFDTAAGFVDPGEKGLAIGTKVPYI
                     VTTTIPKNSTLATAFWSDEMTEGLDYNGDVVVNYNGQPLDNSHYTLEAGHNGFILKLN
                     EKGLEAINGKDAEATITLKYTATLNALAVADVPEANDVTFHYGNNPGHGNTPKPNKPK
                     NGELTITKTWADAKDAPIAGVEVTFDLVNAQTGEVVKVPGHETGIVLNQTNNWTFTAT
                     GLDNNTEYKFVERTIKGYSADYQTITETGKIAVKNWKDENPEPINPEEPRVKTYGKKF
                     VKVDQKDERLKEAQFVVKNEQGKYLALKSAAQQAVNEKAAAEAKQALDAAIAAYTNAA
                     DKNAAQAVVDAAQKTYNDNYRAARFGYVEVERKEDALVLTSNTDGQFQISGLAAGSYT
                     LEETKAPEGFAKLGDVKFEVGAGSWNQGDFNYLKDVQKNDATKVVNKKITIPQTGGIG
                     TIIFAVAGAVIMGIAVYAYVKNNKDEDQLA"
     gene            5180..6361
                     /gene="rrgC"
                     /locus_tag="ACL29Z_001867"
     CDS             5180..6361
                     /gene="rrgC"
                     /locus_tag="ACL29Z_001867"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010963222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PI-1 pilus minor pilin RrgC"
                     /protein_id="HGR0070125.1"
                     /translation="MISRIFFVMALCFSLVWGAHAVQAQEDHTLVLQLENYQEVVSQL
                     PSRDGHRLQVWKLDDSYSYDNRVQIVRDLHSWDENKLSSFKKTSFEMTFLENQIEVSH
                     IPNGLYYVRSIIQTDAVSYPAEFLFEMTDQTVEPLVIVAKKADTVTTKVKLIKVDQDH
                     NRLEGVGFKLVSVARDGSEKEVPLIGEYRYSSSGQVGRTLYTDKNGEIVVTNLPLGTY
                     RFKEVEPLAGYTVTTMDTDVQLVDHQLVTITVVNQKLPRGNVDFMKVDGRTNTSLQGA
                     MFKVMKEENGHYTPVLQNGKEVVVASGKDGRFRVEGLEYGTYYLWELQAPTGYVQLTS
                     PVSFTIGKDTRKELVTVVKNNKRPRIDVPDTGEETLYILMLVAILLFGSGYYLTKKPN
                     N"
     gene            6699..7601
                     /gene="srtC-1"
                     /locus_tag="ACL29Z_001868"
     CDS             6699..7601
                     /gene="srtC-1"
                     /locus_tag="ACL29Z_001868"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000241147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PI-1 pilus system sortase SrtC-1"
                     /protein_id="HGR0070126.1"
                     /translation="MVKTKKQKRNNLLLGVVFFIGMAVMAYPLVSRLYYRVESNQQIA
                     DFDKEKATLDEADIDERMKLAQAFNDSLNNVVSGDPWSEEMKKKGRAEYARMLEIHER
                     MGHVEIPVIDVDLPVYAGTAEEVLQQGAGHLEGTSLPIGGNSTHAVITAHTGLPTAKM
                     FTDLTKLKVGDKFYVHNIKEVMAYQVDQVKVIEPTHFDDLLIVPGHDYVTLLTCTPYM
                     INTHRLLVRGHRIPYVAEVEEEFIAANKLSHLYRYLFYVAVGLIVILLWIIRRLRKKK
                     KQPEKALKALKAARKEVKVEDGQQ"
     gene            7588..8481
                     /gene="srtC-2"
                     /locus_tag="ACL29Z_001869"
     CDS             7588..8481
                     /gene="srtC-2"
                     /locus_tag="ACL29Z_001869"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000370515.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PI-1 pilus system sortase SrtC-2"
                     /protein_id="HGR0070127.1"
                     /translation="MDNSRRSRKKGTKKKKHPLILLLIFLVGFAVAIYPLVSRYYYRI
                     ESNEVIKEFDETVSQMDKAELEERWRLAQAFNATLKPSEILDPFTEQEKKKGVSEYAN
                     MLKVHERIGYVEIPAIDQEIPMYVGTSEDILQKGAGLLEGASLPVGGENTHTVITAHR
                     GLPTAELFSQLDKMKKGDIFYLHVLDQVLAYQVDQIVTVEPNDFEPVLIQHGEDYATL
                     LTCTPYMINSHRLLVRGKRIPYTASIAERNRAVRERGQFWLWLLLGAMAVILLLLYRV
                     YRNRRIVKGLEKQLEGRHVKD"
     gene            8468..9319
                     /gene="srtC-3"
                     /locus_tag="ACL29Z_001870"
     CDS             8468..9319
                     /gene="srtC-3"
                     /locus_tag="ACL29Z_001870"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000091736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PI-1 pilus system sortase SrtC-3"
                     /protein_id="HGR0070128.1"
                     /translation="MSRTKLRALLGYLLMLVACLIPIYCFGQMVLQSLGQVKGHATFV
                     KSMTTEMYQEQQNHSLAYNQRLASQNRIVDPFLAEGYEVNYQVSDDPDAVYGYLSIPS
                     LEIMEPVYLGADYHHLGMGLAHVDGTPLPLDGTGIRSVIAGHRAEPSHVFFRHLDQLK
                     VGDALYYDNGQEIVEYQMMDTEIILPSEWEKLESVSSKNIMTLITCDPIPTFNKRLLV
                     NFERVAVYQKSDPQTAAVARVAFTKEGQSVSRVATSQWLYRGLVVLAFLGILFVLWKL
                     ARLLRGK"
     gene            complement(9392..>9567)
                     /locus_tag="ACL29Z_001871"
     CDS             complement(9392..>9567)
                     /locus_tag="ACL29Z_001871"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014632353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="ISL3 family transposase"
                     /protein_id="HGR0070129.1"
                     /translation="NALQLHYSNAKLEATNNLIKLIKRNAFGFRNFENFKKRIFIALN
                     IKKERTKFVLSRA"
BASE COUNT         3079 a         1568 c         2246 g         2674 t
ORIGIN      
        1 ataaaaatat ctattgtgat ggaagttgtt ttaatttata ctaggatagt taatagtaat
       61 actatactat attgtataca agtgtgtcat tgccaggttg agaagatagc tataacgcac
      121 ttttatacgc ttttgctacg tttgttagtg aacggattaa ctcagtgaga taaattttat
      181 cagaacataa gtaatccgtt tcttcgtgta tacagattga aagtacctat gaatcataga
      241 aggattaact tgttctatga ataatgctta acagggagac acacatgaaa aaagtaagaa
      301 agatatttca gaaggcagtt gcaggactgt gctgtatatc tcagttgaca gctttttctt
      361 cgatagttgc tttagcagaa acgcctgaaa ccagtccagc gataggaaaa gtagtgatta
      421 aggagacagg cgaaggagga gcgcttctag gagatgccgt ctttgagttg aaaaacaata
      481 cggatggcac aactgtttcg caaaggacag aggcgcaaac aggagaagcg atattttcaa
      541 acataaaacc tgggacatac accttgacag aagcccaacc tccagttggt tataaaccct
      601 ctactaaaca atggactgtt gaagttgaga agaatggtcg gacgactgtc caaggtgaac
      661 aggtagaaaa tcgagaagag gctctatctg accagtatcc acaaacaggg acttatccag
      721 atgttcaaac accttatcag attattaagg tagatggttc ggaaaaaaac ggacagcaca
      781 aggcgttgaa tccgaatcca tatgaacgtg tgattccaga aggtacactt tcaaagagaa
      841 tttatcaagt gaataatttg gatgataacc aatatggaat cgaattgacg gttagtggga
      901 aaacagtgta tgaacaaaaa gataagtctg tgccgctgga tgtcgttatc ttgctcgata
      961 actcaaatag tatgagtaac attcgaaaca agaatgctcg acgtgcggaa agagctggtg
     1021 aggcgacacg ttctcttatt gataaaatta catctgatcc agaaaatagg gtagcgcttg
     1081 tgacttatgc ttccactatc tttgatggga ccgagtttac agtagaaaaa ggggtagcag
     1141 ataaaaacgg aaaacgattg aatgattctc ttttttggaa ttatgatcag acgagtttta
     1201 caaccaatac caaagattat agttatttaa agctgactaa tgataagaat gacattgtag
     1261 aattaaaaaa taaggtacct accgaggcag aagaccatga tggaaataga ttgatgtacc
     1321 aattcggtgc cacttttact cagaaagctt tgatgaaggc agatgagatt ttgacacaac
     1381 aagcgagaca aaatagtcaa aaagtcattt tccatattac ggatggtgtc ccaactatgt
     1441 cgtatccgat taattttaat catgctacgt ttgctccatc atatcaaaat caactaaatg
     1501 cattttttag taaatctcct aataaagatg gaatactatt aagtgatttt attacgcaag
     1561 caactagtgg agaacataca attgtacgcg gagatgggca aagttaccag atgtttacag
     1621 ataagacagt ttatgaaaaa ggtgctcctg cagctttccc agttaaacct gaaaaatatt
     1681 ctgaaatgaa ggcggctggt tatgcagtta taggcgatcc aattaatggt ggatatattt
     1741 ggcttaattg gagagagagt attctggctt atccgtttaa ttctaatact gctaaaatta
     1801 ccaatcatgg tgaccctaca agatggtact ataacgggaa tattgctcct gatgggtatg
     1861 atgtctttac ggtaggtatt ggtattaacg gagatcctgg tacggatgaa gcaacggcta
     1921 ctagttttat gcaaagtatt tctagtaaac ctgaaaacta taccaatgtt actgacacga
     1981 caaaaatatt ggaacagttg aatcgttatt tccacaccat cgtaactgaa aagaaatcaa
     2041 ttgagaatgg tacgattaca gatccgatgg gtgagttaat tgatttgcaa ttgggcacag
     2101 atggaagatt tgatccagca gattacactt taactgcaaa cgatggtagt cgcttggaga
     2161 atggacaagc tgtaggtggt ccacaaaatg atggtggttt gttaaaaaat gcaaaagtgc
     2221 tctatgatac gactgagaaa aggattcgtg taacaggtct gtaccttgga acggatgaaa
     2281 aagttacgtt gacctacaat gttcgtttga atgatgagtt tgtaagcaat aaattttatg
     2341 ataccaatgg tcgaacaacc ttacatccta aggaagtaga acagaacaca gtgcgcgact
     2401 tcccgattcc taagattcgt gatgtgcgga agtatccaga aatcacaatt tcaaaagaga
     2461 aaaaacttgg tgacattgag tttattaagg tcaataaaaa tgataaaaaa ccactgagag
     2521 atgcggtctt tagtcttcaa aaacaacatc cggattatcc agatatttat ggagctattg
     2581 atcaaaatgg cacttatcaa aatgtgagaa caggtgaaga tggtaagttg acctttaaaa
     2641 atctgtcaga tgggaaatat cgattatttg aaaattctga accagctggt tataaacccg
     2701 ttcaaaataa gcctatcgtt gccttccaaa tagtaaatgg agaagtcaga gatgtgactt
     2761 caatcgttcc acaagatata ccagcgggtt acgagtttac gaatgataag cactatatta
     2821 ccaatgaacc tattcctcca aagagagaat atcctcgaac tggtggtatc ggaatgttgc
     2881 cattctatct gataggttgc atgatgatgg gaggagttct attatacaca cggaaacatc
     2941 cgtaaagtgt agaaatgata atatctatgt tctgaacgat acttttaaga agtagcactc
     3001 aagaagagat ttaagtttac ttggtgaaac ctgttttatt cgtaagtaaa ctatcattga
     3061 aaggggagat gttttcgaaa acttgcacag aaaaaggatt attattgtca tgtgtaattc
     3121 attacattgc tcacagttga ttttaagaga tatgaataag gagaaatcat gaaatcaatc
     3181 aacaaatttt taacaatact tgctgcctta ttactgacag tgagtagcct gttctcagct
     3241 gcaacagttt ttgcggcgga acaaaaaact aagacactta cagttcataa attattgatg
     3301 acagatcaag agcttgacgc ttggaattct gatgcgatta ctactgcagg ttatgacggt
     3361 tcgcaaaatt ttgaacagtt caaacaactt caaggtgttc cacaaggagt aaccgaaatc
     3421 tctggtgttg cattcgagtt acagagttat acgggtcctc aaggaaaaga acaagaaaat
     3481 ttaacgaatg atgcggtttg gactgcggtt aataaaggtg tgacgactga aacgggtgtt
     3541 aaatttgata ctgaagtttt acaagggaca tatcgtcttg tcgaagtacg taaagaatcg
     3601 acttatgtcg gtccaaatgg taaagtttta acaggtatga aagctgttcc tgctttaatt
     3661 attctgccgc ttgtaaacca aaatggtgtt gtagaaaatg cacatgtcta tccaaagaat
     3721 tctgaagaca aacctacagc aacgaaaaca tttgatactg cagcaggttt cgtagatcca
     3781 ggtgaaaaag gtttagcaat tggcactaag gtaccgtata ttgttacaac aactattccg
     3841 aaaaactcaa ctcttgcaac agctttctgg tcagatgaaa tgacagaagg tctagattat
     3901 aatggtgatg tagttgttaa ttataatggt caaccgcttg ataattctca ttacacatta
     3961 gaagcaggtc ataatggctt tatcttgaag ttaaatgaaa aaggtctgga agcaatcaac
     4021 ggtaaagatg cagaagcaac aattacgttg aagtatactg caactttaaa tgctcttgct
     4081 gttgctgatg tgccagaagc gaatgatgta acattccatt atggaaacaa cccaggtcat
     4141 ggtaacactc caaaaccaaa caaacctaaa aacggtgaac ttacaattac taaaacatgg
     4201 gctgatgcta aagatgctcc tatagcaggt gtagaagtaa cttttgattt ggtaaatgct
     4261 cagacaggtg aggtcgttaa agtacctgga catgaaacag gtattgtatt gaatcaaaca
     4321 aataattgga catttactgc tacaggtctt gataataata cagaatataa atttgttgaa
     4381 cggacaatta agggatattc tgcagattac caaacaatta ctgaaacagg aaaaattgct
     4441 gttaaaaact ggaaagatga aaatccagaa ccaataaatc ctgaagagcc acgtgtaaaa
     4501 acatatggta aaaaattcgt taaggttgac caaaaagacg aacgcttaaa agaagcacaa
     4561 ttcgttgtga agaatgagca agggaaatat cttgcactca aatctgcagc acaacaagct
     4621 gtaaatgaga aagctgccgc agaagcgaaa caagcgctag atgcagcgat agcagcctat
     4681 acaaatgctg cagataaaaa tgcagcacaa gctgtagtag atgctgcgca aaaaacatat
     4741 aatgacaatt acagagcagc tagatttggc tatgtagaag tagagagaaa agaagatgcg
     4801 ttagttctta cttctaacac tgatggtcaa ttccaaattt caggtcttgc tgctggaagc
     4861 tacacgttgg aagaaacaaa agctccagaa ggctttgcaa aacttggaga tgtgaagttt
     4921 gaggttggag caggttcttg gaatcaaggt gatttcaatt atttaaaaga tgttcagaag
     4981 aacgacgcta caaaagtagt caacaaaaaa atcacgatcc ctcaaacggg tggtattggt
     5041 acaattatct ttgctgtagc gggggctgtg attatgggta ttgcagtgta cgcatatgtt
     5101 aaaaacaaca aagatgagga tcaacttgct taagtaagag agaaaggagc cattgatgac
     5161 aatgcagaaa atgcagaaaa tgattagtcg tatcttcttt gttatggctc tgtgtttttc
     5221 tcttgtatgg ggtgcacatg cagtccaagc gcaagaagat cacacgttgg tcttgcaatt
     5281 ggagaactat caggaggtgg ttagtcaatt gccatctcgt gatggtcatc ggttgcaggt
     5341 atggaagttg gatgattcgt attcctatga taatcgggtg caaattgtga gagacttgca
     5401 ttcgtgggat gagaataaac tttcttcttt caaaaagact tcgtttgaga tgaccttcct
     5461 tgagaatcag attgaagtat ctcatattcc aaatggtctt tactatgttc gctctattat
     5521 ccagacggat gcggtttctt atccagctga atttcttttt gaaatgacag atcagacggt
     5581 agagcctttg gtcattgtag cgaaaaaagc agatacggtg acaacaaagg tgaagctgat
     5641 aaaggtggat caagaccaca atcgcttgga gggtgtcggc tttaaattgg tatcagtagc
     5701 aagagatggt tctgaaaaag aggttccctt gattggagaa taccgttaca gttcttctgg
     5761 tcaagtaggt agaactctct atactgataa aaatggagag attgttgtga caaatcttcc
     5821 tcttgggacc tatcgtttca aggaggtgga gccactggca ggctatactg ttacgacgat
     5881 ggatacggat gtccagttgg tagatcatca gctggtgacg attacggttg tcaatcagaa
     5941 attaccacgt ggcaatgttg actttatgaa ggtggatggt aggaccaata cctctcttca
     6001 aggggcaatg ttcaaagtca tgaaagaaga aaacggacac tatactcctg ttcttcaaaa
     6061 tggtaaggaa gtagttgtgg catcagggaa agatggtcgt ttccgagtgg aaggtctaga
     6121 gtatgggaca tactatttat gggagctcca agctccaact ggttatgttc aattaacatc
     6181 gcctgtttcc tttacaatcg ggaaagatac tcgtaaggaa ctggtaacag tggttaaaaa
     6241 taacaagcga ccacggattg atgtgccaga tacaggggaa gaaaccttgt atatcttgat
     6301 gcttgttgcc attttgttgt ttggtagtgg ttattatctt acgaaaaaac caaataactg
     6361 atattcaatg tacatcatta tgaaaaagat agcaggctga agggaagacc agagtactct
     6421 gaggtgatgt taatcaggaa tcatggtgat gtggcatgaa tcacaataac ggatatgagg
     6481 ctgggcagat tgtgccagcc tcattgtggg ttattgtttg taaaacgata ggactggtct
     6541 ggtaatcatt ttaggaatgg acaggactgg gattctgatt taaaatggat ggtgaatcag
     6601 aaagaaatga gattttctcg tttctcttag cagataggat tgtctgttag gaaaagcgat
     6661 aaaatgatga gtttgaagat aaagggatgc tgataaaaat ggtaaaaaca aaaaagcaaa
     6721 aacgaaataa tctcctatta ggagtggtat ttttcattgg aatggcggta atggcgtatc
     6781 cgctggtgtc tcgcttgtat tatcgagtgg aatcaaatca acaaattgct gactttgata
     6841 aggaaaaagc aacgttggat gaggctgaca ttgatgaacg aatgaaattg gcacaagcct
     6901 tcaatgactc tttgaataat gtagtgagtg gcgatccttg gtcggaagaa atgaagaaaa
     6961 aagggcgagc agagtatgca cgtatgttag aaatccatga gcggatgggg catgtggaaa
     7021 tccccgttat tgacgtggat ttgccggttt atgctggtac tgctgaagag gtattgcagc
     7081 aaggggctgg gcatctagag ggaacttctc tgccgatcgg aggcaattcg acccatgcgg
     7141 tgattacggc acatacaggt ttgccaacag ctaagatgtt tacggatttg accaaactta
     7201 aagttgggga taagttttat gtgcacaata tcaaggaagt gatggcctat caagtggatc
     7261 aagtaaaggt gattgagccg acgcactttg atgatttatt gattgtacca ggtcatgatt
     7321 atgtgacctt gctgacttgt acgccataca tgatcaatac ccatcgtcta ttggttcggg
     7381 ggcatcggat accgtacgta gcagaggttg aggaagaatt tattgcagca aacaaactca
     7441 gtcatctcta tcgctacctg ttttatgtgg cagttggttt gattgtgatt cttttatgga
     7501 ttattcgacg cttgcgcaag aagaaaaaac aaccggaaaa ggctttgaag gcgctgaaag
     7561 cagcaaggaa ggaagtgaag gtggaggatg gacaacagta gacgttcacg aaaaaaaggc
     7621 acaaaaaaga agaaacatcc gctgatcctt cttctgattt tcttagtagg attcgccgtt
     7681 gcgatatatc cattggtgtc tcgttattat tatcgtattg agtcaaacga ggttattaaa
     7741 gagtttgatg agacggtttc ccagatggat aaggcagaac ttgaggagcg ttggcgcttg
     7801 gctcaagcct tcaatgcgac cttgaaacca tctgaaattc ttgatccttt tacagagcaa
     7861 gagaaaaaga aaggcgtctc agaatatgcc aatatgctaa aggtccatga gcggattggc
     7921 tatgtggaaa ttcctgcgat tgatcaggaa attccgatgt atgtcggaac gagtgaggac
     7981 attcttcaga aaggggcagg gctgttagaa ggggcttcgc tgcctgttgg aggtgaaaat
     8041 acccatacag tgatcactgc tcacagagga ttgccaacgg cagaattgtt cagtcaattg
     8101 gataagatga aaaaagggga tatcttttat cttcacgttt tagatcaggt gttggcctac
     8161 caagtggatc agatagtgac ggtggagccg aatgactttg agcctgtctt gattcaacat
     8221 ggggaagatt atgcgacctt gttgacttgt acaccgtata tgattaacag tcatcgtctg
     8281 ttggtacgtg ggaagcggat tccgtatacg gcatcaattg cagagcggaa tcgagcggtg
     8341 agagagcgtg ggcaattctg gttgtggtta ttactaggag cgatggcggt catccttctc
     8401 ttgctgtatc gcgtgtatcg taatcgacgg attgtcaaag gactagaaaa gcaattggag
     8461 gggcgtcatg tcaaggacta aactacgagc cttattggga tacttgttga tgttggtagc
     8521 ctgtttgatt cctatttatt gttttggaca gatggtgttg cagtctcttg gacaggtgaa
     8581 aggtcatgct acatttgtga aatccatgac aactgaaatg taccaagaac aacagaacca
     8641 ttctctcgcc tacaatcaac gcttggcttc gcaaaatcgc attgtagatc cttttttggc
     8701 ggagggatat gaggtcaatt accaagtgtc tgacgaccct gatgcagtct atggttactt
     8761 gtctattcca agtttggaaa tcatggagcc ggtttatttg ggagcagatt atcatcattt
     8821 agggatgggc ttggctcatg tggatggtac accgctgcct ctggatggta cagggattcg
     8881 ctcagtgatt gctgggcacc gtgcagagcc aagccatgtc tttttccgcc atttggatca
     8941 gctaaaagtt ggagatgctc tttattatga taatggccag gaaattgtag aatatcagat
     9001 gatggacaca gagattattt taccgtcgga atgggaaaaa ttagaatcgg ttagctctaa
     9061 aaatatcatg accttgataa cctgcgatcc gattcctacc tttaataaac gcttattagt
     9121 gaattttgaa cgagtcgctg tttatcaaaa atcagatcca caaacagctg cagttgcgag
     9181 ggttgctttt acgaaagaag gacaatctgt atcgcgtgtt gcaacctctc aatggttgta
     9241 ccgtgggcta gtggtactgg catttctggg aatcctgttt gttttgtgga agctagcacg
     9301 tttactacga gggaaataaa aagaaatgaa aggaaagcta aggctgttcc tttttccggc
     9361 tctttgtcaa ctgtagtggg ttgaaaaaaa gctaagctcg agaaaggaca aattttgtcc
     9421 tttctttttt gatattcaga gcgataaaaa tccgtttttt gaagttttca aagtttcgaa
     9481 aaccaaaggc attgcgcttg ataagtttga tgagattatt ggtcgcttcc agtttggcat
     9541 tagaatagtg tagttgaagg gcgttga
//
LOCUS       DBEJAU010000065         9534 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC323 isolate 683620
            SAMN38261939-rid24807223.denovo.065, whole genome shotgun sequence.
ACCESSION   DBEJAU010000065 DBEJAU010000000
VERSION     DBEJAU010000065.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261939
            Sequence Read Archive: SRR26833919
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 9534)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9534)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576303.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576303.1
            Genome Coverage       :: 154x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/19/2025 01:05:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,121
            CDSs (total)                      :: 2,078
            Genes (coding)                    :: 1,943
            CDSs (with protein)               :: 1,943
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 36
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 72 of 135
            Pseudo Genes (incomplete)         :: 63 of 135
            Pseudo Genes (internal stop)      :: 51 of 135
            Pseudo Genes (multiple problems)  :: 46 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9534
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261939-rid24807223.denovo.065"
                     /strain="GPSC323"
                     /isolate="683620"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            1..476
                     /locus_tag="ACL29Z_001872"
                     /pseudo
     CDS             1..476
                     /locus_tag="ACL29Z_001872"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="internal stop; incomplete; missing N-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=3
                     /transl_table=11
                     /product="transposase"
     gene            376..822
                     /locus_tag="ACL29Z_001873"
     CDS             376..822
                     /locus_tag="ACL29Z_001873"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864098.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HGR0070130.1"
                     /translation="MRKHGLISKSTSKRYYQVAIPFTRLFCPTLVSIDYINCLSETID
                     KNWHKSDRIFVTNTGKPVHSSILSKSLQRANERLKKPIPKHLSPHIFRHTTISILSEN
                     KIPLKTITDRVGHSDSEVTTSIYTHVTKNMKDEAINVLDKVMKKIF"
     gene            complement(960..2264)
                     /gene="eno"
                     /locus_tag="ACL29Z_001874"
     CDS             complement(960..2264)
                     /gene="eno"
                     /locus_tag="ACL29Z_001874"
                     /EC_number="4.2.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="surface-displayed alpha-enolase"
                     /protein_id="HGR0070131.1"
                     /translation="MSIITDVYAREVLDSRGNPTLEVEVYTESGAFGRGMVPSGASTG
                     EHEAVELRDGDKSRYGGLGTQKAVDNVNNIIAEAIIGYDVRDQQAIDRAMIALDGTPN
                     KGKLGANAILGVSIAVARAAADYLEIPLYSYLGGFNTKVLPTPMMNIINGGSHSDAPI
                     AFQEFMILPVGAPTFKEALRYGAEIFHALKKILKSRGLETAVGDEGGFAPRFEGTEDG
                     VETILAAIEAAGYVPGKDVFIGFDCASSEFYDKERKVYDYTKFEGEGAAVRTSAEQID
                     YLEELVNKYPIITIEDGMDENDWDGWKALTERLGKKVQLVGDDFFVTNTDYLARGIQE
                     GAANSILIKVNQIGTLTETFEAIEMAKEAGYTAVVSHRSGETEDSTIADIAVATNAGQ
                     IKTGSLSRTDRIAKYNQLLRIEDQLGEVAEYRGLKSFYNLKK"
     gene            2428..2874
                     /locus_tag="ACL29Z_001875"
     CDS             2428..2874
                     /locus_tag="ACL29Z_001875"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000131081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YueI family protein"
                     /protein_id="HGR0070132.1"
                     /translation="MTDLSKQLLEKAHGGLKINPDEQRRYLGTFEERVLGYVDIDTAN
                     SPQLEKGFLFILENLQEKAEPLFVKISPTIEFDKQVFYLKEAKETDSQATIVSEEHIT
                     SPFGLVIHSNAPVQVEEKDLRLAFPKLWEVKKEEPAKTSLWKKWFS"
     gene            complement(2871..3986)
                     /locus_tag="ACL29Z_001876"
     CDS             complement(2871..3986)
                     /locus_tag="ACL29Z_001876"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000706318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008887 - glycerate kinase activity
                     [Evidence IEA];
                     GO_process: GO:0031388 - organic acid phosphorylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycerate kinase"
                     /protein_id="HGR0070133.1"
                     /translation="MKIVIAPDSFKESLTAQQVAEAIKRGFQQSIADVEYLLCPVGDG
                     GEGTVDAIRHSLDLKEKWIQVTDPFGQKEAMRYFQKGELALFEVADLVGLGKIPLEKR
                     NPLQIQTCGIGELILHLISKGIKDIYIGVGGTASNDGGLGIAAGLGYQFYDRDGNVLP
                     ASGQSLLNLASVSTENCYKIPEGVQIHILADVVSPLCGHQGATYTFGNQKGLHPTMFA
                     VVDQAIQDFYEKFSPATLEIKGAGSGGGLAGGLCAFAQASIVSGIDTCLDLINFNKKV
                     SDADLVVVGEGRLDSQSFAGKAPIGVAKRTPVGVPVIAICGSLAEDLPPLPFENIQAV
                     FSILEKSEPLEDSLKNASLYLERTAANIGHLLNMYKI"
     gene            complement(3995..4228)
                     /locus_tag="ACL29Z_001877"
     CDS             complement(3995..4228)
                     /locus_tag="ACL29Z_001877"
                     /inference="COORDINATES: protein motif:HMM:NF019887.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD hydrolase family protein"
                     /protein_id="HGR0070134.1"
                     /translation="MISPQVKKETLEKWRKKLKLSKERTVAIGDGVNNLLMLKSAELG
                     IAFCAKEVLKKEIPHHVDKRDFLEVLPLIDRLE"
     gene            complement(4269..4640)
                     /locus_tag="ACL29Z_001878"
     CDS             complement(4269..4640)
                     /locus_tag="ACL29Z_001878"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809343.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA];
                     GO_process: GO:0008152 - metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HAD-IB family phosphatase"
                     /protein_id="HGR0070135.1"
                     /translation="MSQVKGLCVLDVDGTLILEEVIDLLGREAGHEAEISQITSRAMR
                     GELVFESSLRKRVSLLEGLPILVFDNVFNSIHLSLNVPEFISILQKNGILVGLVSGGF
                     TPIVGEISKIPWYCLFHCQLA"
     gene            complement(4699..6132)
                     /gene="glgA"
                     /locus_tag="ACL29Z_001879"
     CDS             complement(4699..6132)
                     /gene="glgA"
                     /locus_tag="ACL29Z_001879"
                     /EC_number="2.4.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000697278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004373 - glycogen (starch) synthase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycogen synthase GlgA"
                     /protein_id="HGR0070136.1"
                     /translation="MKILFVAAEGAPFSKTGGLGDVIGALPKSLVKAGHEVAVILPYY
                     DMVEAKFGNQIEDVLHFEVSVGWRRQYCGIKKTVLNGVTFYFIDNQYYFFRGHVYGDF
                     DDGERFAFFQLAAIEAMERIDFIPDLLHVHDYHTAMIPFLLKEKYRWIQAYEDIETVL
                     TIHNLEFQGQFSEGMLGDLFGVGLERYADGTLRWNNCLNWMKAGILYANRVSTVSPSY
                     AHEIMTSQFGCNLDQILKMESGKVSGIVNGIDADLYNPQTDALLDYHFNQEDLSGKAK
                     NKAKLQERVGLPVRADVPLVGIVSRLTRQKGFDVVVESLHHILQEDVQIVLLGTGDPA
                     FEGAFSWFAQIYPDKLSTNITFDVKLAQEIYAACDLFLMPSRFEPCGLSQMMAMRYGT
                     LPLVHEVGGLRDTVRAFNPIEGSGTGFSFDNLSPYWLNWTFQTALDLYRNHPDIWRNL
                     QKQAMESDFSWDTACKSYLDLYHSLVN"
     gene            complement(6129..7268)
                     /gene="glgD"
                     /locus_tag="ACL29Z_001880"
     CDS             complement(6129..7268)
                     /gene="glgD"
                     /locus_tag="ACL29Z_001880"
                     /EC_number="2.7.7.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008878 - glucose-1-phosphate
                     adenylyltransferase activity [Evidence IEA];
                     GO_process: GO:0005978 - glycogen biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-1-phosphate adenylyltransferase subunit
                     GlgD"
                     /protein_id="HGR0070137.1"
                     /translation="MKIDKYSAILGNTVGFHNMSTLTDHRPVASLPFGGKYRLIDFPL
                     SSLANAGVRSVFGIFQQDNISSVFDHIRSGREWGLSTLLSHYYLGIYNTRVESSTVGK
                     EYYQQLLTYLKRSGSNQTVALNCDVLINIDLNQVFHLHSTTKEPITVVYKKLAKKDIS
                     EVNAILDVDETDHVLSHKLFDSKSTAEMFNMSTDIFVVDTPWLIEHLEEEAKKEHPKK
                     LRYVLRDLAVKEGAFAYEYTGYLANIHSVKSYYQANIDMLESQKFYSLFSPNQKIYTK
                     VKNEEPTYYANTSKVSTSQFASGSIIEGQVANSVLSRNIHVHKDSLVKDSLLFPRVVI
                     GKGAQVEYAILDKGVEVEPGVVIRGTAEHPVVVKKGAKVTEDIHS"
     gene            complement(7258..8400)
                     /locus_tag="ACL29Z_001881"
     CDS             complement(7258..8400)
                     /locus_tag="ACL29Z_001881"
                     /EC_number="2.7.7.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000787267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008878 - glucose-1-phosphate
                     adenylyltransferase activity [Evidence IEA];
                     GO_process: GO:0005978 - glycogen biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-1-phosphate adenylyltransferase"
                     /protein_id="HGR0070138.1"
                     /translation="MKNEMLALILAGGQGTRLGKLTQSIAKPAVQFGGRYRIIDFALS
                     NCANSGIHNVGVVTQYQPLALNNHIGNGSSWGLDGINSGVSILQPYSASEGNRWFEGT
                     SHAIYQNIDYIDSVNPEYVLILSGDHIYKMDYDDMLQSHKDNNASLTVAVLDVPLKEA
                     SRFGIMNTDANNRIVEFEEKPAQPKSTKASMGIYIFDWQRLRNMLVAAEKSKVGMSDF
                     GKNVIPNYLESGESVYAYEFSGYWKDVGTIESLWEANMEYISPENALDSRNRQWKIYS
                     RNLISPPNFLGANAHVEDSLVVDGCFVDGAVKHSILSTGAQVREGAEVLDSVIMSGAI
                     IGQGAKIKRAIIGEGAIISDGVEIDGTDEVQVVGYNEVVGVATDED"
     gene            complement(8390..>9534)
                     /gene="glgB"
                     /locus_tag="ACL29Z_001882"
     CDS             complement(8390..>9534)
                     /gene="glgB"
                     /locus_tag="ACL29Z_001882"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003844 - 1,4-alpha-glucan branching
                     enzyme activity [Evidence IEA];
                     GO_function: GO:0004553 - hydrolase activity, hydrolyzing
                     O-glycosyl compounds [Evidence IEA];
                     GO_function: GO:0043169 - cation binding [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA];
                     GO_process: GO:0005978 - glycogen biosynthetic process
                     [Evidence IEA]"
                     /codon_start=3
                     /transl_table=11
                     /product="1,4-alpha-glucan branching protein GlgB"
                     /protein_id="HGR0070139.1"
                     /translation="KAHNHGWGALNFDLGKNEVQSFLISCIKHWIDVYHLDGIRVDAV
                     SNMLYLDYDNAPWTPNKDGGNLNYEGYYFLQRLNEVIKLEYPDVMMIAEESSSATKIT
                     GMKEIGGLGFDYKWNMGWMNDILRFYEEDPIYRKYDFNLVTFSFMYVFKENYLLPFSH
                     DEVVHGKKSMMHKMWGDRYNQFAGLRNLYTYQICHPGKKLLFMGSEYGQFLEWKSEEQ
                     LEWSNLEDPMNAKMKYFTSQLNQFYKDHRCLWEIDTSYDGIEIIDADNRDQSVLSFIR
                     KGKKGEMLVCIFNMVPVERKDFTIGLPVAGIYEEVWNTELEEWGGVWKEHNQTVQTQE
                     GLWKDYEQTLTFTLPAMGASVWKIKRRLKSTKTVTNKNQKGVENEK"
BASE COUNT         2900 a         2082 c         1697 g         2855 t
ORIGIN      
        1 tatttcttaa gaattttaat agattaaagc acctagcacc tgtttagatt gacgaaacag
       61 gattcgatac ttatttttat cgagaatatg gtcgctcttt aaaaggtcag ttaagaagaa
      121 gatatcagag gatttctttg gttgcaggtc taaccaatgg tgagttaatc gctccaatga
      181 cttacgaaga gacgatgacg agcgactttt ttgaagcatg gtttcagaag tttctcttac
      241 caacattaac cacaccatcg gttgttatta tggataatgc aagattccat agaatgggta
      301 agttagaact cttgtgtgaa gagtttgggc ataaactttt acctcttcct ccctactcac
      361 ctgagtacaa tcctattgag aaaacatggg ctcatatcaa aaagcacctc aaaaaggtat
      421 taccaagttg caataccttt tacgaggctc ttttgtccta ctcttgtttc aattgactat
      481 ataaattgtc taagcgaaac aatcgataag aattggcaca aaagcgaccg tatttttgtt
      541 accaatacag gaaaaccagt tcatagttct atcttgagca agtctctcca gcgagcaaac
      601 gaacgcctta aaaaaccaat tcccaaacat ctgtcccctc acatcttcag acacaccact
      661 attagcatct tatcagaaaa taaaattcct ttaaaaacaa tcacggacag ggttggtcat
      721 tccgactctg aagtcactac ttccatctac acccacgtca caaagaacat gaaagatgaa
      781 gcaatcaatg tactggataa agttatgaaa aagatttttt aaaaagtttt gtcccttttt
      841 tgtcctctaa atacaaaaat agcccttcgg ataaaatccg aggagctaga aacgttgtta
      901 aatcaacggc cgaacttttg aatttcatgg ttcgggataa aatagttcac tgaactattt
      961 tattttttaa ggttgtagaa tgatttcaat ccacgatatt cagctacttc accaagttgg
     1021 tcttcgatac gaagcaattg gttgtattta gcgatgcggt ctgtacgtga aagtgaacca
     1081 gtcttgattt gtcctgcgtt agttgcaact gcaatatcag cgattgttga atcttcagtt
     1141 tcacctgaac ggtgtgatac aacagcagtg taaccagctt ctttagccat ttcgatagct
     1201 tcaaaagttt cagtaagagt accgatttgg ttaactttga taaggattga gttagcagca
     1261 ccttcttgga taccacgtgc aaggtagtca gtgtttgtta cgaagaagtc gtcaccaaca
     1321 agttgtactt tcttaccaag acgttcagta agagctttcc aaccatccca gtcgttttca
     1381 tccataccat cttcaatagt gatgattggg tatttgttaa ccaattcttc aaggtagtcg
     1441 atttgttctg cagatgtacg aacagcagca ccttcacctt caaatttagt gtagtcgtaa
     1501 actttacgtt ctttatcgta gaattctgat gaagcacagt caaatccgat aaatacgtct
     1561 ttacctggta catatccagc agcttcaatc gcagcaagga tagtttcaac accatcttca
     1621 gttccttcga aacgaggagc gaatccacct tcgtcaccta cggcagtttc caaaccacgt
     1681 gatttaagga ttttcttaag agcgtggaag atttcagcac cgtaacgaag ggcttcttta
     1741 aatgttggcg caccaactgg caagatcatg aactcttgga aagcgattgg agcgtcagag
     1801 tgagaaccac cgttgatgat gttcatcatt ggagttggaa gaactttagt gttgaatcca
     1861 ccaagatagc tgtaaagtgg gatttcaagg tagtcagcag cagcacgagc tacagcgata
     1921 gacacaccga ggattgcatt cgcacccaat ttacctttgt taggagtacc gtcaagtgcg
     1981 atcatagcac ggtcaatagc ttgttgatca cgtacatcgt agccaatgat agcttcagca
     2041 atgatgttgt ttacgttgtc aacagctttt tgtgtaccaa gaccaccgta acgagatttg
     2101 tcaccgtcgc gaagttcaac tgcttcgtgt tcaccagtag aagctcctga tggaaccata
     2161 ccacgtccga aagcacctga ttcagtgtaa acttctactt caagtgttgg gttaccgcgt
     2221 gagtctagga cttcgcgagc gtaaacatca gtaataattg acatttttta ctctccttat
     2281 gagttaaatt ttttacacct ctataatacc ttaaaacccc tcctttttca agaaaaaacg
     2341 ttatctttgt gcaacttttc cttaacttta taaagtaatc gctttctttt gtctgtttta
     2401 ttctaacttt tatgatatac tgttttcatg acagatttat caaaacaatt acttgaaaaa
     2461 gctcatggtg ggttaaaaat aaatccggat gagcaaagac gctatcttgg tacttttgag
     2521 gaaagagttc ttggatatgt agatattgac acagcaaata gccctcagtt agaaaaaggc
     2581 tttttattta ttttagaaaa ccttcaggaa aaagcagagc cactatttgt gaagatttca
     2641 ccaactatcg aatttgataa gcaagttttc tacttaaaag aagcaaaaga aactgatagt
     2701 caagccacca tagtatctga agagcatatt acttctcctt ttggcctggt tattcatagc
     2761 aatgcaccag ttcaagtaga agaaaaagac cttcgacttg cttttccaaa actttgggaa
     2821 gttaaaaagg aagaaccagc caaaacatcc ttatggaaga aatggtttag ctaaatcttg
     2881 tacatattta ataagtgccc aatattggca gccgtgcgct ccagatagag actggcattt
     2941 tttaaactat cttctaaagg ttcacttttc tccaaaatag aaaagacagc ttggatattt
     3001 tcaaatggta ggggaggtaa atcttcagca agactaccgc aaatagcaat aacaggaact
     3061 ccaacagggg ttctttttgc aacacctata ggcgctttcc cagcaaagct ttgactatca
     3121 agccttcctt ctccaacaac aaccaagtca gcatctgaaa ctttcttatt aaagttgatt
     3181 aagtccaagc aggtatcaat tccagacacg atacttgcct gagcaaaggc acacaaacca
     3241 ccagcaaggc ctccacctga tcctgctcct ttaatttcta atgttgcagg tgagaatttt
     3301 tcataaaaat cttggatcgc ctgatctacg actgcaaaca tagtcggatg tagacctttt
     3361 tgattaccaa aagtgtaagt cgcaccttga tgaccacata agggactcac gacatctgct
     3421 agaatatgaa tttgaacacc ttcaggaatt ttatagcaat tttctgttga aacagaagct
     3481 aagtttaata aggattgacc ggaagcaggc aagacatttc catccctatc ataaaattga
     3541 taacctaaac cagcagcaat ccccagtcct ccatcattac tggccgtgcc accaacaccg
     3601 atataaatat ctttaatccc tttagaaatg agatggagaa tcaactctcc aataccacaa
     3661 gtttggattt gaagtggatt tcgcttctct agcggaattt ttccaagacc aaccaaatca
     3721 gctacttcaa atagtgccag ttcccctttt tgaaaatagc gcatggcttc tttttgtcca
     3781 aaagggtctg tcacttggat ccatttttct tttaggtcaa gagaatgtcg gatagcatct
     3841 acagtacctt ctcccccatc accaacaggg cagaggagat attctacatc tgctatcgat
     3901 tgttggaagc ctctttttat tgcttcagct acctgttgag ctgtcaagct ttccttaaac
     3961 gaatccggtg caattacaat cttcatattt tccctcattc taaacggtca atcaaaggaa
     4021 gaacttctaa aaaatccctc ttgtcaacat gatgtggtat ttcttttttg agcacttctt
     4081 tggcacaaaa ggcgattcct aactccgccg acttcaacat taatagatta ttaaccccat
     4141 caccgattgc caccgttctt tctttagaaa gttttagttt ctttctccat ttttccagag
     4201 tctctttttt gacctgggga cttataattt gtccaactaa ttttcctgtt aaaagacctt
     4261 ctttgacttc aagctagttg gcagtgaaat aggcaatacc aagggatttt gctaatctct
     4321 ccaactattg gtgtaaatcc accagacacc agaccaacta ggatgccatt cttttggaga
     4381 atagagatga actctgggac atttagcgat agatgaattg agttgaagac gttatcaaag
     4441 accaaaatag gaagaccttc caacaaggac actctttttc ttaaactgct ttcaaagacc
     4501 aactctcctc gcattgctcg acttgtaatc tgcgaaattt ccgcctcatg acctgcctct
     4561 ctccctaaaa gatcaatcac ttcttctagg attaaggttc catctacatc caaaacacac
     4621 aagcctttta cttgagacat cagttctcct ctctaaacag cctaaaaatc gtatgaagtc
     4681 atcatacgat tttatctatt aattaactaa actatggtac aagtcaaggt atgacttgca
     4741 ggctgtatcc catgagaagt cactctccat agcttgtttt tgtaggtttc tccaaatgtc
     4801 tggatggttt ctatacaagt ccaatgctgt ttggaaagtc caatttaacc aataaggaga
     4861 tagattgtca aagctaaagc cagtaccgct tccttcgatt ggattgaaag cgcgaactgt
     4921 atctcgcaag cctccaactt catggaccaa tggcaaggtt ccataacgca tagccatcat
     4981 ttgagacaag ccacacggtt caaaacgact tggcatgagg aagaggtcac aagcagcgta
     5041 gatttcctga gcaagtttga catcaaaagt gatatttgtt gatagcttgt ctgggtaaat
     5101 ctgagcaaac catgagaaag ctccttcaaa ggctggatcg ccagttccca aaagaacaat
     5161 ctgaacatct tcttgcaaga tatggtgaag actttcgacc accacatcaa aacctttttg
     5221 acgtgtcaaa cgagaaacaa ttcccaccag tggaacgtct gctctaacag gcaagccaac
     5281 tctttcttgc aattttgcct tatttttggc tttcccagac aaatcttcct gattgaaatg
     5341 atagtctaaa agagcatccg tctgaggatt ataaagatca gcatcaatcc cattcacgat
     5401 accagatact ttaccagact ccattttaag aatctgatcc aaattacatc caaactgact
     5461 agtcataatt tcatgagcat agctaggtga aacggttgaa acacggttcg catagagaat
     5521 acctgccttc atccagttca gacagttgtt ccatcgaagg gtgccatcag cgtaacgttc
     5581 aaggccaact ccaaacaaat cacccaacat tccttctgaa aattgtcctt ggaattctaa
     5641 attatgaatg gttaaaactg tttcaatgtc ctcataggct tgaatccaac ggtatttttc
     5701 cttcaacaag aaaggaatca tagctgtatg gtagtcatga acatggagaa gatcaggaat
     5761 aaagtcaatc ctttccatag cctcaatggc agccagttgg aaaaaggcaa agcgttctcc
     5821 gtcatcaaaa tcaccgtaaa catgaccacg gaagaaataa tattgattgt caataaagta
     5881 gaaggttaca ccatttaata ctgttttctt aattccacaa tactgtctgc gccaaccaac
     5941 gctcacctca aaatgaagca catcttcaat ctgatttcca aatttagcct ctaccatatc
     6001 atagtagggt aaaatcactg caacttcgtg cccagctttt accagtgatt ttggaagagc
     6061 gccaatgacg tctcccaaac cacctgtttt tgaaaaaggt gcaccctctg ctgctacaaa
     6121 taaaattttc atgaatgaat atcctctgtt actttagcac ctttcttaac cacaactgga
     6181 tgttctgcag ttcctcgaat cacaacacca ggctcaactt caaccccttt gtccaagata
     6241 gcatattcga cctgagcccc ttttccaata acaacacgag ggaagagcag gctatcttta
     6301 accaagctat ccttatggac atgaatatta cgtgatagaa cagaattagc tacttgacct
     6361 tcaataatac taccagaggc aaactgagaa gtgcttacct tagatgtatt agcatagtaa
     6421 gttggctctt cgtttttgac ctttgtataa atcttttggt ttggtgagaa aagagaatag
     6481 aatttttgtg attcaagcat atcgatattc gcttgataat aagatttaac agagtgaata
     6541 ttggctagat agcccgtgta ctcgtaggcg aaagctccct cttttacagc caaatcccgt
     6601 aaaacatagc gcaatttctt tggatgttct tttttagctt cttcttccaa gtgttcaatc
     6661 aaccaaggtg tatcaacgac aaagatatct gtagacatat tgaacatttc agctgttgac
     6721 ttgctatcaa agagtttatg agaaagaaca tggtctgttt catctacatc caagattgca
     6781 tttacttctg aaatatcttt cttagctagt tttttataaa ctacagtgat aggctctttt
     6841 gttgtactat gtaggtggaa aacttggttc aaatcaatgt taataagaac atcgcagttg
     6901 agggcaaccg tttggtttga gccagaacgt ttcaaataag taagaagctg ttggtagtat
     6961 tcttttccaa ctgtactact ttctacacgg gtattgtaaa ttcctagata gtaatgacta
     7021 agaagggttg ataagcccca ctcgcgtcct gaacgaatat ggtcaaatac tgagctgata
     7081 ttatcctgct ggaaaatacc aaagacacta cgaacacctg cattagcaag gcttgaaagt
     7141 gggaagtcaa tcaaacgata tttcccacca aatggcaaac ttgctactgg acggtggtcc
     7201 gtcaatgtcg acatattgtg aaaaccaact gtatttccta aaatggcaga atatttatca
     7261 atcttcatct gttgctaccc ccactacttc attatatcct acaacttgta cttcatctgt
     7321 tccatcaatt tcgacaccgt cagaaataat cgcaccttca ccaataatgg cacgtttaat
     7381 cttagctcct tgaccaatga tagctccact catgataact gaatcaagga cttccgctcc
     7441 ttcgcgaact tgcgcgcctg ttgaaaggat agaatgttta acagctccat caacgaaaca
     7501 tccgtctaca actaatgagt cttccacatg agcatttgcc ccgaggaagt ttggtggtga
     7561 aatcaagttt cttgagtaaa tcttccattg acggttacga ctatccaagg cattttctgg
     7621 agaaatatac tccatgttcg cttcccaaag tgactcaata gtaccaacat ctttccaata
     7681 accactaaat tcgtaagcat aaacactttc acctgactca aggtaatttg gaatgacatt
     7741 tttaccaaag tctgacatgc caaccttgct cttttcagca gcgactaaca tattacgaag
     7801 gcgttgccaa tcaaaaatgt agattcccat agaagctttt gtagatttag gttgagctgg
     7861 tttttcttca aattcaacaa tacgattgtt agcatctgtg ttcatgatac caaaacggct
     7921 tgcttcttta agagggacgt ctaaaactgc tactgtcaag ctggcattat tatccttatg
     7981 agactggagc atatcatcat agtccatttt gtagatgtgg tccccagaca aaatcaagac
     8041 atactcagga ttgacactgt cgatatagtc gatattttgg taaatagcgt gactagttcc
     8101 ctcaaaccaa cgatttcctt cacttgcaga ataaggttga agaatagaga cgcctgaatt
     8161 aataccgtct agtccccagc ttgaaccatt cccaatatgg ttgttgagag caagtggttg
     8221 atactgtgta acgaccccaa cattatgaat ccctgagttg gcacagtttg atagggcaaa
     8281 gtcaatgata cggtagcgcc caccaaattg cacagctggt tttgcgatgc tttgagtgag
     8341 tttaccgaga cgagttcctt gcccaccagc aagaatcaaa gctaacattt catttttcat
     8401 tttctactcc tttttggttt ttatttgtga cggttttagt agatttcaag cgacgtttga
     8461 ttttccatac acttgctccc atagccggta gagtaaaggt taaggtctgc tcataatctt
     8521 tccataggcc ttcttgcgtt tgaacagttt gattatgttc tttccaaacg cctccccact
     8581 cttccaactc agtattccat acttcttcgt aaattcctgc aacgggtagt ccgattgtaa
     8641 aatctttccg ctcaacaggt accatgttaa agatacagac taacatttct ccctttttac
     8701 ccttacgaat aaaggaaaga acactctggt ctcgattatc cgcatcaatg atttcaatac
     8761 catcatagct ggtatcgatt tcccacagac agcgatgatc tttgtaaaac tggtttagct
     8821 gagaagtgaa atacttcatc ttagcattca ttgggtcttc taggttagac cattccaact
     8881 gttcttcaga tttccattct aggaattgac cgtattcgct acccatgaag agcaatttct
     8941 taccagggtg acaaatttgg tacgtataga gattgcgcaa gcctgcgaat tgattgtaac
     9001 gatctcccca catcttatgc atcatactct tcttgccatg aaccacttca tcgtgcgaga
     9061 atggcaagag ataattctcc ttgaaaacat acataaagct gaaagtcacc aggttaaagt
     9121 catatttacg ataaatcgga tcttcttcgt agaaacggag gatatcattc atccagccca
     9181 tgttccattt gtagtcaaat cctagaccac caatctcttt cattcccgta atcttggtcg
     9241 cagacgaact ttcttctgca atcatcatca catctggata ttctaactta ataacttcat
     9301 tcaagcgttg aagaaaataa taaccttcat agttgagatt tccgccatct ttattaggtg
     9361 tccatggagc attatcatag tccaaataga gcatgttgct aacagcatcc acacgaatac
     9421 catccaaatg atagacatca atccaatgct taatgcaaga aattaagaag gactggactt
     9481 cattttttcc aaggtcaaaa ttaagggcac cccaaccatg gttatgagcc ttat
//
LOCUS       DBEJAU010000066         9429 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC323 isolate 683620
            SAMN38261939-rid24807223.denovo.066, whole genome shotgun sequence.
ACCESSION   DBEJAU010000066 DBEJAU010000000
VERSION     DBEJAU010000066.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261939
            Sequence Read Archive: SRR26833919
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 9429)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9429)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576303.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576303.1
            Genome Coverage       :: 154x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/19/2025 01:05:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,121
            CDSs (total)                      :: 2,078
            Genes (coding)                    :: 1,943
            CDSs (with protein)               :: 1,943
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 36
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 72 of 135
            Pseudo Genes (incomplete)         :: 63 of 135
            Pseudo Genes (internal stop)      :: 51 of 135
            Pseudo Genes (multiple problems)  :: 46 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9429
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261939-rid24807223.denovo.066"
                     /strain="GPSC323"
                     /isolate="683620"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            1..1106
                     /locus_tag="ACL29Z_001883"
                     /pseudo
     CDS             1..1106
                     /locus_tag="ACL29Z_001883"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611513.1"
                     /note="frameshifted; internal stop; incomplete; missing
                     N-terminus; Derived by automated computational analysis
                     using gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /pseudo
                     /codon_start=2
                     /transl_table=11
                     /product="IS3 family transposase"
     gene            complement(1234..1482)
                     /locus_tag="ACL29Z_001884"
     CDS             complement(1234..1482)
                     /locus_tag="ACL29Z_001884"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000155489.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HGR0070140.1"
                     /translation="MASTSLQAPAKICFILIKLYSPYAFLSKYLGAILLSFFCYYAKE
                     IGCNNLTLSVWNDNEGALRFYQRQGMKPQETTMEMIID"
     gene            complement(1430..2512)
                     /locus_tag="ACL29Z_001885"
     CDS             complement(1430..2512)
                     /locus_tag="ACL29Z_001885"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000040939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008233 - peptidase activity [Evidence
                     IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="M24 family metallopeptidase"
                     /protein_id="HGR0070141.1"
                     /translation="MSKLQQILTYLESEKLDVAVVSDPVTINYLTDFYSDPHERQMFL
                     FVLADQEPLLFVPALEVERASSTVSFPVVGYVDSENPWQKIKHALPQLDFKRVAVEFD
                     NLILTKYHGLKTVFETAEFDNLTPRIQRMRLIKSADEVQKMMVAGLYADKAVHVGFDN
                     ISLDKTETDIIAQIDFAMKREGYEMSFDTMVLTGDNAANPHGIPAANKVENDALLLFD
                     LGVLVNGYASDMTRTVAVGKPDQFKKDIYNLTLEAQQAALDFIKPGVTAHEVDRAARE
                     VIEKAGYGEYFNHRLGHGIGMDVHEFPSIMEGNDMVIEEGMCFSVEPGIYIPGKVGVR
                     IEDCGVVTKDGFDLFTSTSKDLLYFD"
     gene            complement(2638..3420)
                     /gene="gatD"
                     /locus_tag="ACL29Z_001886"
     CDS             complement(2638..3420)
                     /gene="gatD"
                     /locus_tag="ACL29Z_001886"
                     /EC_number="6.3.5.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004359 - glutaminase activity [Evidence
                     IEA];
                     GO_function: GO:0140282 - carbon-nitrogen ligase activity
                     on lipid II [Evidence IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="lipid II isoglutaminyl synthase subunit GatD"
                     /protein_id="HGR0070142.1"
                     /translation="MVYTSLSSKDGNYPYQLNIAHLYGNLMNTYGDNGNILMLKYVAE
                     KLGAHVTVDIVSLHDDFDENHYDIAFFGGGQDFEQSIIADDLPAKKESIDNYIQNDGV
                     VLAICGGFQLLGQYYVEASGKRIEGLGVMGHYTLNQTNNRFIGDIKIHNEDFDETYYG
                     FENHQGRTFLSDDQKPLGQVVYGNGNNEEKVGEGVHYKNVFGSYFHGPILSRNANLAY
                     RLVTTALKKKYGQDIQLPAYEDILSQEIAEEYSDVKSKADFS"
     gene            complement(3420..4763)
                     /gene="murT"
                     /locus_tag="ACL29Z_001887"
     CDS             complement(3420..4763)
                     /gene="murT"
                     /locus_tag="ACL29Z_001887"
                     /EC_number="6.3.5.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011836724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016881 - acid-amino acid ligase activity
                     [Evidence IEA];
                     GO_function: GO:0140282 - carbon-nitrogen ligase activity
                     on lipid II [Evidence IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="lipid II isoglutaminyl synthase subunit MurT"
                     /protein_id="HGR0070143.1"
                     /translation="MNLKTTLGLLAGRSSHFVLSRLGRGSTLPGKVALQFDKDILQNL
                     AKNYEIVVVTGTNGKTLTTALTVGILKEVYGQVLTNPSGANMITGIATTFLTAKSSKT
                     GKNIAVLEIDEASLSRICDYIQPSLFVITNIFRDQMDRFGEIYTTYNMILDAIRKVPT
                     ATVLLNGDSPLFYKPTIPNPIEYFGFDLEKGPAQLAHYNTEGILCPDCQGILKYEHNT
                     YANLGAYICEGCGCKRPDLDYRLTKLVELTNNRSRFVIDGQEYGIQIGGLYNIYNALA
                     AVAIARFLGADSQLIKQGFDKSRAVFGRQETFHIGDKECTLVLIKNPVGATQAIEMIK
                     LAPYPFSLSVLLNANYADGIDTSWIWDADFEQITDMDIPEINAGGVRHSEIARRLRVT
                     GYPAEKITETSNLEQVLKTIENQDCKHAYILATYTAMLEFRELLASRQIVRKEMN"
     gene            complement(4862..6178)
                     /locus_tag="ACL29Z_001888"
     CDS             complement(4862..6178)
                     /locus_tag="ACL29Z_001888"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000958936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016668 - oxidoreductase activity, acting
                     on a sulfur group of donors, NAD(P) as acceptor [Evidence
                     IEA];
                     GO_function: GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA];
                     GO_process: GO:0045454 - cell redox homeostasis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-containing oxidoreductase"
                     /protein_id="HGR0070144.1"
                     /translation="MLTYDLIVIGFGKAGKTLAGKLASAGKKVALVERSKAMYGGTCI
                     NIGCIPTKTLLVAAEKDLSFEEVIATKNTITGRLNGKNYTTVAGTGVNIFDAEAHFLS
                     NKVIEIQAGDEKQELTAETIVINTGAVSNVLPIPGLATSKNVFDSTGIQSLDKLPEKL
                     GVLGGGNIGLEFAGLYNKLGSKVTVLDALDTFLPRAEPSIAALAKQYLEEDGIELLQN
                     IHTTEIKNDGDQVLVVTEDETYRFDALLYATGRKPNVEPLQLENTDIELTERGAIKVD
                     KHCQTNVPGVFAVGDVNGGLQFTYISLDDFRVVYSYLAGDGSYTLEDRLNVPNTMFIT
                     PALSQVGLTESQAADLKLPYAVKEIPVAAMPRGHVNGDLRGAFKAVVNTETKEILGAS
                     IFSEGSQEIINIITVAMDNKIPYTYFTKQIFTHPTLAENLNDLFAI"
     gene            6371..7597
                     /locus_tag="ACL29Z_001889"
     CDS             6371..7597
                     /locus_tag="ACL29Z_001889"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000841575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="OFA family MFS transporter"
                     /protein_id="HGR0070145.1"
                     /translation="MKSNRYIIALAGFILHLMLGSTYAWSVYRNPIIEKTGWDQASVA
                     FAFSLAIFCLGLSAAFMGRLVEKFGPKVMGSLSAFLYAGGNILTGFAIDRQELWLLYL
                     AYGILGGLGLGAGYITPVSTIIKWFPDKRGLATGLAIMGFGFASLLTSPIAQHLIAGV
                     GIVETFYILGASYFIIMLLASQFIKRPNEQELAILSSSGKEKTASLTQGMAANQALKS
                     NRFYMLWIIFFINIACGLGLISAASPMAQEMAGLSTSHAAVMVGVLGIFNGFGRLLWA
                     SLSDYIGRPLTFSILLLVNLFFSLSLWLFTDSVLFVVAMSILMTCYGAGFSLIPAYLS
                     DIFGTKELAALHGYILTAWAMAGLAGPILLAETYKMAHSYTQTLFVFLILYSIALALS
                     YYLGRSIKKESQKPLT"
     gene            7796..9370
                     /locus_tag="ACL29Z_001890"
     CDS             7796..9370
                     /locus_tag="ACL29Z_001890"
                     /EC_number="3.6.4.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000671067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004386 - helicase activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HGR0070146.1"
                     /translation="MKFNELNLSADLLAEIEKAGFVEASPIQEQTIPLALEGKDVIGQ
                     AQTGTGKTAAFGLPTLEKIRTEEATIQALVIAPTRELAVQSQEELFRFGRSKGVKVRS
                     VYGGSSIEKQIKALKSGAHIVVGTPGRLLDLIKRKALKLQDIETLILDEADEMLNMGF
                     LEDIEAIISRVPENRQTLLFSATMPDAIKRIGVQFMKAPEHVKIAAKELTTELVDQYY
                     IRVKEQEKFDTMTRLMDVAQPELAIVFGRTKRRVDELTRGLKIRGFRAEGIHGDLDQN
                     KRLRVLRDFKNGNLDVLVATDVAARGLDISGVTHVYNYDIPQDPESYVHRIGRTGRAG
                     KSGQSITFVAPNEMGYLQIIENLTKKRMKGLKPASVEESFQSKKQVALKKIERDFADE
                     TIRANFEKFGKDARKLAAEFTPEELAMYILSLTVQDPDSLPEVEIAREKPLPFKPSGN
                     GFGGKAKGGRGGRRGDDRRERDRRGNGRRDEFKKGSRGNDRFDKEKRYRKDNKKPRNT
                     LSEKQTGFVIRNKGDK"
BASE COUNT         2770 a         1816 c         2081 g         2762 t
ORIGIN      
        1 agtttctctt gaatacggtc tcccaagtcg tacgatactt cttaactggc tagcacaata
       61 caggaaaaac gggtatacta ttgttgagaa aacaagaggg agagtaccta aaatgggacg
      121 taagccaaaa aagagacctg aagagaggac agaattagaa cgtcttcaag cagaaaatga
      181 gtacctgaga gcggagaatg ccatcctaaa aaagttaaga gaactccgat tgaaggagga
      241 aaaagagaaa gacagaaatt gtttaagaat taatgactga gttttcgtta gatcttcttc
      301 taaaagccat taaactagct cgttggacct actactatca cttgaaacag ctagacaaaa
      361 cagataagga ccaagagctt aaagctgaaa ttcaatccat ttttatcgaa cacaagggaa
      421 attatgctta tcgtcgaatt catttagaac taagaaatcg tggttatctg gtaaatcata
      481 aaagagttca aggcttgatg aaagtactca atttacaagc taaaatgcga cagaaacgaa
      541 aatattcttc tcataaagga gacgttggta agaaagcaga gaatctcatt caaggccaat
      601 ttgaaggctc taaaacaatg gaacagtgct acacagatgt gactgaattt gccattccag
      661 caagtactca aaagctttac ttatcaccag ttttagatgg ctttaatagc gaaattatcg
      721 cctataatct ttcaacttca cccaacttag aacaagtgaa gagtatgtta gaacaggcct
      781 ttacagagaa gcactacgag aatacgattc tccatagtga ccaaggctgg caataccgac
      841 acgattctta tcatcggttc ctagagagta agggaattca agcatccatg tcacgtaagg
      901 gtaacagccc agacaatggt atgatggagt ccttctttgg gattctgaaa tcggaaatgt
      961 tttacggttt tgagaagtcg tttcagtcgc ttaagcaatt ggaacaagct attatagact
     1021 atattgatta ctacaacaat aaacgaatta aggtaaaact aaaaggactt atccctgtgc
     1081 aatacagaac taaatccttc ggataaatta attgtctaac tttttggggg gcagttcatt
     1141 ctacacccac tattatgcgt tttattgtgg gaagattttc ctcattttct agtgaaattg
     1201 aactttttct aacatctttt gatagatgac ttcttaatca attatcattt ccattgttgt
     1261 ttcttggggt ttcatccctt gtctttgata aaagcggaga gcaccctcgt tatcattcca
     1321 gacacttagg gttagattat tgcagccaat ttctttagca taatagcaga aaaatgacaa
     1381 taaaatagcc cctagatatt ttgaaaggaa agcatagggg ctatatagtt taatcaaaat
     1441 aaagcaaatc tttgctggtg cttgtaaaga ggtcgaagcc atccttggta acaacaccgc
     1501 agtcttcaat acgaacaccg actttaccag ggatatagat acctggttca acagagaagc
     1561 acatgccttc ttcgatgacc atgtcgtttc cttccatgat agatgggaat tcatggacat
     1621 ccataccgat accatgcccg agacggtggt tgaagtactc accataacca gctttttcga
     1681 tgacctcacg ggcagcgcgg tccacttcat gagcagtcac acctggcttg ataaagtcaa
     1741 gagcagcttg ttgggcttca agagtcaagt tgtaaatatc tttcttgaat tggtctggtt
     1801 tgccgacagc gactgtacga gtcatatctg acgcatagcc attgaccaga acacccaggt
     1861 caaagaggag aagagcatca ttttcaacct tattagctgc tggaatgccg tgtggattcg
     1921 cagcattatc accagtcaag accatggtat caaagctcat ttcgtaacct tcacgtttca
     1981 tggcaaagtc aatttgtgcg atgatatctg tctcagtctt atcaagagaa atattgtcaa
     2041 aaccaacatg aacagccttg tcagcataaa gacctgcaac catcattttt tgcacttcat
     2101 cagctgattt gatgaggcgc atgcgttgga tacgaggagt gaggttgtca aactcagcag
     2161 tctcaaaaac tgttttcaaa ccatggtatt tggtcaagat gagattgtca aactcaacag
     2221 cgacacgttt gaagtcaagt tgtggaagag catgtttgat tttttgccat ggattttcag
     2281 aatcgacata gcccactact gggaaggaaa cggtgctact tgcacgttct acttcaagag
     2341 ctgggacaaa gaggagaggt tcctgatctg ctaggacaaa gaggaacatt tggcgttcat
     2401 ggggatcact gtaaaaatca gtgaggtaat tgattgtgac ggggtcagat acgacagcga
     2461 cgtctagttt ttctgattca agatatgtta ggatttgttg taatttagac atatgctacc
     2521 ttctttctac ccctctattt tggcaaaaaa tgagagaaaa tgcaagggag aagggtaaaa
     2581 gaaaagacaa aaaactccga caagataacg gagttctttg atatcatttt cctttgttta
     2641 agaaaagtca gccttgcttt tgacgtcact gtactcttca gcgatttctt ggctgagaat
     2701 gtcctcatag gcagggagtt ggatgtcctg accatatttc ttcttgaggg cagtagtaac
     2761 taggcgataa gccagattgg cattacgaga gaggataggc ccgtggaagt aggaaccaaa
     2821 gacattctta taatgaaccc cttcaccgac cttttcttcg ttgtttccat ttccatagac
     2881 aacctgtccc agcggttttt ggtcatcaga gaggaaggta cgaccttggt gattttcaaa
     2941 tccatagtag gtttcatcga aatcttcatt gtgaatcttg atgtcaccga taaaacggtt
     3001 attggtctgg ttgagcgtgt agtgtcccat gacccctagc ccttcgatac gttttcctga
     3061 agcttcaaca taatattgac ccaatagttg gaaaccaccg cagatagcca gaactacacc
     3121 gtcgttttgg atgtagttgt caatgctctc ttttttagca ggtaggtcgt ctgcaatgat
     3181 actttgttca aagtcttgac caccaccgaa aaaggcgatg tcgtagtgat tttcatcaaa
     3241 gtcatcatgg agagaaacga tgtcaacggt cacatgggct cccagttttt cagccacata
     3301 cttgagcatg aggatgtttc cattgtcccc gtaggtattc atgagatttc cgtagaggtg
     3361 ggcaatgttg agctgatagg ggtaattgcc atcttttgag gaaagtgaag tataaaccat
     3421 tagttcatct cctttctaac aatctgacga ctagccagca gttcacgaaa ttccagcatg
     3481 gcagtataag ttgccagaat ataggcatgc ttgcagtctt gattctcaat ggtcttgaga
     3541 acttgctcca gattactcgt ttcagtgatt ttctcagctg gatagccagt cactcggagg
     3601 cgacgagcga tttcagaatg acgaacaccg ccagcgttga tttcaggaat gtccatgtca
     3661 gtgatttgct caaagtctgc atcccagatc cagctagtgt caattccatc tgcatagttg
     3721 gcattaagga ggacagatag gctaaatgga taaggtgcta gtttgatcat ttcgatagct
     3781 tgggttgcac cgactggatt tttaatcaag acaagggtac attccttgtc accgatatga
     3841 aaggtttctt ggcgtccaaa gacagcacgg ctcttgtcaa atccctgttt gatgagttgg
     3901 gaatctgcgc cgaggaaacg ggcgatggcc acagcagcta gggcgttata gatattatag
     3961 agcccgccga tttggatacc gtattcttgg ccgtctatga caaagcgaga gcgattgttg
     4021 gtcaactcaa ccagttttgt caaacgatag tcgagatcag gacgtttaca tccacaaccc
     4081 tcacagatat aggcacccaa gtttgcatag gtattatgct catatttgag gatgccttgg
     4141 cagtcaggac agagaatccc ttcggtattg tagtgagcca gttgggctgg tcctttttcc
     4201 aagtcaaaac caaaatactc tatagggttt ggaatagttg gcttgtagaa aagtggactg
     4261 tctccgttaa ggagaacagt agcagttgga actttccgaa tggcatccaa tatcatgtta
     4321 taggtagtat agatttcacc gaaacggtcc atctggtcac ggaagatatt agtaatgaca
     4381 aaaagactag gctggatata gtcacagata cgagatagac tggcttcgtc aatttcgagg
     4441 acggcaatat ttttcccagt tttagaagat ttggctgtta ggaaggttgt tgcaatccct
     4501 gtaatcatgt tggcaccgct tggattggtt agaacttgac catagacctc ttttaaaatg
     4561 ccgacagtga gggcagttgt cagggttttt ccatttgttc cagtgacaac gacaatctcg
     4621 tagttcttag ctaggttttg taaaatatct ttatcaaatt gaagggcgac tttccctggg
     4681 agcgtacttc cacgtccaag acggcttaaa acgaagtggg aagaacgtcc agcaagaagg
     4741 cccaaagtag tttttaagtt catgtttcta ttatatcaca aaagagggaa aagacagatt
     4801 tggtgtttcg tagaagtaaa aacagcccaa agagggctgt cagttaagat gagatttcaa
     4861 cttaaatcgc aaacaagtca ttcaagttct cagccaaggt tgggtgagtg aagatttgtt
     4921 ttgtgaagta agtgtaagga atcttgttgt ccatagcaac agtaatgatg ttgatgattt
     4981 cttgagaacc ttctgagaag atgcttgcac caagaatttc ttttgtttca gtattaacaa
     5041 cagctttgaa agctccgcga aggtctccat ttacgtgacc acgaggcatg gctgcaacag
     5101 ggatttcttt cactgcgtat ggaagtttca aatcagctgc ttggctttca gtcaaaccaa
     5161 cttgtgaaag tgcaggtgtg atgaacatag tatttggcac attgagacgg tcctcaagtg
     5221 tgtagctgcc atctccagca aggtagctgt aaacaacacg gaagtcatca agtgaaatgt
     5281 aagtaaattg aagaccaccg ttgacatctc caactgcaaa gacaccagga acgtttgttt
     5341 gacagtgttt atctacttta atagcgccac gttcagttag ttcaatatct gtattttcaa
     5401 gttgaagtgg ttctacattt ggtttgcgtc cagttgcgta gagaagggcg tcgaaacggt
     5461 aagtttcgtc ttcagttacg acaagcactt ggtcaccgtc gtttttaatt tcagtagtat
     5521 ggatattttg aagcaattca ataccgtctt cttccaggta ttgtttagca agagctgcga
     5581 tggaaggttc tgcacgaggt aggaatgtat ccaaggcatc taggactgta accttgcttc
     5641 ctagtttatt gtaaaggcca gcaaattcaa gaccgatatt tccgccacca aggactccaa
     5701 gtttttcagg caatttatcc aagctttgga tacctgttga gtcaaagacg tttttgcttg
     5761 tagcaagtcc agggattggc aagacgtttg aaacagcacc agtgttgatg acgatagttt
     5821 cagcagtcaa ttcttgtttt tcatcaccag cttggatttc gatgacttta tttgaaagga
     5881 agtgagcttc agcatcaaag atattgacgc cagtaccagc aacagtcgta tagtttttac
     5941 cgttgaggcg accagtgatc gtgtttttgg tagcaatgac ttcttcaaaa gacaagtctt
     6001 tctcagcagc aaccagcaaa gttttagttg ggatacaacc gatgttgata caagttccac
     6061 cgtacatagc tttgctacgt tcaacgaggg caactttttt gccagctgaa gccaatttac
     6121 ctgctagtgt tttaccagct ttaccaaatc caataacaat taaatcgtat gttaacattt
     6181 atcttcctcc tattcgaatt tcattctagc acaagaaaaa aacttttgca caattctgct
     6241 acggaaaaga cagaaaaaga taaaaacgct ttccagacaa aaaactagta attttttgac
     6301 aagcttgata aactaaaatc ctatctattt ttatataaga aagaataaat gttcgaaaat
     6361 aggaggtttt atgaaatcga atcgttatat tattgccctt gctgggttca ttttacactt
     6421 aatgctgggt tcgacttatg cttggagtgt ttatcgtaac cctattattg aaaaaacggg
     6481 atgggatcag gcttctgttg ccttcgcctt tagtctagca atcttttgtt tgggcttatc
     6541 ggctgcattt atggggcgtt tggtagaaaa atttggtccg aaagtcatgg ggagtctatc
     6601 tgcttttcta tacgcaggtg gaaatatctt aacaggattt gcaatagacc gtcaggaact
     6661 gtggttgttg tatctagctt atggcatttt aggtgggctt ggtttgggag caggctatat
     6721 tacccctgtg tcaacgatta taaaatggtt tcctgataaa cgtggtctcg caacaggttt
     6781 agcgattatg gggtttggtt ttgcttcttt attgactagt cccatagcgc aacacctcat
     6841 cgcaggggta gggattgtag aaacttttta tattttagga gcaagttact ttattatcat
     6901 gctcctagct tcacaattca ttaagcgtcc aaatgagcaa gagcttgcaa ttttatcttc
     6961 ttcagggaaa gaaaaaacag cctctttgac gcaaggaatg gctgcaaatc aggctctaaa
     7021 aagcaatcgg ttttatatgc tttggattat tttctttatc aacatagctt gtggtttagg
     7081 cttaatttca gcggcatcgc caatggcaca ggagatggct ggcttgtcta caagtcatgc
     7141 agcagtaatg gtgggtgttt tggggatttt caatggattt ggtcgcttgc tctgggcgag
     7201 tttgtctgac tatatcggtc gccctctaac ctttagtata ttactgcttg tcaatctttt
     7261 cttttctctc tcactttggc tctttacaga ttccgtttta tttgtagttg ctatgtctat
     7321 tttgatgact tgctatggag ctggtttttc attgattcca gcttatctca gtgatatttt
     7381 tggaaccaag gaattggccg ctctgcatgg ttatatttta acagcttggg caatggctgg
     7441 tttagcggga cctattttat tagcagagac ttataaaatg gctcattcgt acacacaaac
     7501 cttgttcgtt tttctcattt tatacagtat cgccttggct ttgtcttatt atctaggtcg
     7561 ttcaatcaaa aaagaaagtc aaaaaccgct tacatgattt tctgtagaaa tggggctatc
     7621 ttttgctctg gtcttgtgtt atactagata ggttgcaaag aaaacagtac ttttcttttg
     7681 tggaaaagaa gcaacacgat tttatatcta gttatatgaa aatacgtcat aaaaagaaaa
     7741 gtataaacta agccctatag ggtggcttcg caccaccttt agaaagaaga ataacgtgaa
     7801 atttaatgaa ttaaacttgt ctgctgattt gctagcagaa attgaaaaag ctggttttgt
     7861 agaagctagt cctatccaag aacaaactat tcctttggcc cttgaaggca aggatgttat
     7921 tggtcaagct cagactggta caggaaaaac tgcagccttt ggcttgccta cccttgaaaa
     7981 aatccgtaca gaagaagcga ctatccaagc tttggtcatc gctccaactc gtgaactagc
     8041 tgtccaaagt caagaagaac tcttccgctt tggtcgtagt aagggagtca aagtccgttc
     8101 agtatatggc ggatcaagca ttgaaaaaca aattaaggct cttaaatctg gtgcccatat
     8161 cgtggtggga actccaggtc gcctcttgga cttgattaaa cgcaaggcct tgaaattaca
     8221 agacattgaa acccttatcc ttgacgaagc ggatgaaatg cttaacatgg gcttccttga
     8281 agacatcgaa gccattattt cccgtgtacc tgagaaccgt caaactttgc ttttctcagc
     8341 aactatgcca gatgccatca aacgtatcgg tgttcagttt atgaaagccc ctgaacatgt
     8401 caagattgcg gctaaggaat tgacaacaga attggttgac cagtactata tccgtgttaa
     8461 ggaacaagaa aaatttgaca ccatgactcg tctcatggat gtggcacaac cagaactcgc
     8521 tattgtattt ggtcgtacca aacgccgtgt ggatgaattg actcgtggtt tgaaaattcg
     8581 tggcttccgt gcagaaggaa ttcatggcga cctagaccaa aataaacgtc ttcgtgtcct
     8641 tcgtgacttt aaaaatggca atcttgatgt tttggttgcg acagacgttg cagcgcgtgg
     8701 tttggatatt tcaggtgtga cccatgtcta caactacgat attccacaag atcctgagag
     8761 ttatgttcac cgtatcggtc gtacaggtcg tgctggtaag tcaggtcaat ctattacttt
     8821 tgttgctcca aacgaaatgg gttaccttca aatcattgaa aacttgacta agaaacgcat
     8881 gaaaggtctc aaacctgcaa gtgtagaaga atccttccaa tcaaaaaaac aggtagctct
     8941 caagaaaatc gaacgtgatt ttgcagatga aaccattcgt gccaactttg agaaatttgg
     9001 taaggatgct cgcaaattgg ctgctgagtt tactccagaa gaattggcaa tgtatatctt
     9061 gagtctgaca gtccaagacc cagatagcct tccagaagtg gagattgcac gtgaaaaacc
     9121 actaccgttt aaaccatcag gtaatggttt cggtggtaaa gctaagggag gtcgtggagg
     9181 ccgtcgtggg gacgaccgtc gagagcgtga tcgccgtggc aatggtcgcc gtgatgagtt
     9241 caaaaaagga agtcgtggca acgatcgttt tgataaggaa aaacgttacc gtaaggataa
     9301 taaaaaacca cgcaatactt taagcgaaaa gcaaacaggc tttgttattc gtaacaaggg
     9361 cgataaataa gaaaaagcgg ttcaaaatga atcgcttttt tatataagga gaccgaatgt
     9421 gaaaagaca
//
LOCUS       DBEJAU010000067         9347 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC323 isolate 683620
            SAMN38261939-rid24807223.denovo.067, whole genome shotgun sequence.
ACCESSION   DBEJAU010000067 DBEJAU010000000
VERSION     DBEJAU010000067.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261939
            Sequence Read Archive: SRR26833919
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 9347)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9347)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576303.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576303.1
            Genome Coverage       :: 154x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/19/2025 01:05:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,121
            CDSs (total)                      :: 2,078
            Genes (coding)                    :: 1,943
            CDSs (with protein)               :: 1,943
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 36
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 72 of 135
            Pseudo Genes (incomplete)         :: 63 of 135
            Pseudo Genes (internal stop)      :: 51 of 135
            Pseudo Genes (multiple problems)  :: 46 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9347
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261939-rid24807223.denovo.067"
                     /strain="GPSC323"
                     /isolate="683620"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            93..1271
                     /locus_tag="ACL29Z_001891"
     CDS             93..1271
                     /locus_tag="ACL29Z_001891"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000175872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family transcriptional regulator"
                     /protein_id="HGR0070147.1"
                     /translation="MTLSKKQLQLRAKILETVYTLGPISRIEIATKTGITPATTSSIT
                     NDLIKENILLELGEDEHDTSVGRKKILLDIQAKRFYYIGCELSEKHFTFALGDNLGNI
                     LKEEKEIVTKQLIQEKGNQLINQTLKQFLNNCSDYEIEAIGIALPGRYLDDYKITTNN
                     PLWQHIDLEMIQSHFDKPLFFSNNVNCMAIGKRLFSRQQNDPNFAYFHFARGMHCSYI
                     YDGNIYGKGNLMIGEIGHTVVSSEGEECSCGRKGCLQTFAGESWLIKKSKILYHQSPY
                     SLLPSLVKNADDIDIQVILTAYQLGDTGIITLIHQALLYLSQTILNISMMIDSQKIYL
                     HSPLLTNQHIIQKLYSEMNYKPKLLYNRLPEVIIEPYNDFTAAHLAIALCLYHTILHS
                     "
     gene            complement(1499..1945)
                     /locus_tag="ACL29Z_001892"
     CDS             complement(1499..1945)
                     /locus_tag="ACL29Z_001892"
                     /EC_number="2.3.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000155432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0016746 - acyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HGR0070148.1"
                     /translation="MTIRFEEKVSIENAQFVCQWSNSLGKSFQEQWMGPRIPFLLTLQ
                     ALEGVFSIFDEQEFVGLIQKIRLEDSNLHIGRFFINPQKQGQGLDSQALRKFVSLAFE
                     NEDIDSISLNVFEANQRAQNLYQKEGFEIVQMVEAPVRKYSELKLE"
     gene            2015..2674
                     /locus_tag="ACL29Z_001893"
     CDS             2015..2674
                     /locus_tag="ACL29Z_001893"
                     /EC_number="3.4.23.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000564993.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0004190 - aspartic-type endopeptidase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="A24 family peptidase"
                     /protein_id="HGR0070149.1"
                     /translation="MIDIYFFLVGSILASFLGLVIDRFPEQSIISSASHCDSCQTRLH
                     PLDLIPILSQVFNRFRCRYCKVRYPVWYALFELGLGLLFLLYSWELLSLGQVVLITAG
                     LTLGIYDFHHQEYPLLVWMTFHLILIASSGWNLVMVSFLILGILAHFIDIRMGAGDFL
                     FLASCALVFSVTELLILIQFASATGILAFLLQKKKERLPFVPFLLLATCLIIFGKLLL
                     V"
     gene            complement(2646..3422)
                     /gene="trpA"
                     /locus_tag="ACL29Z_001894"
     CDS             complement(2646..3422)
                     /gene="trpA"
                     /locus_tag="ACL29Z_001894"
                     /EC_number="4.2.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004834 - tryptophan synthase activity
                     [Evidence IEA];
                     GO_process: GO:0000162 - tryptophan biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan synthase subunit alpha"
                     /protein_id="HGR0070150.1"
                     /translation="MPKTLTEKLNAIKATGKGIFVPYIMAGDHEKGLDGLAETIHFLE
                     DLGVSAIEVGIPFSDPVADGPVIEEAGLRSLAHGTSTQALVETLKTIETEIPLVIMTY
                     FNPLFQYGVENFVKDLADTAVKGLIIPDLPHEHANFVEPFLADTDIALIPLVSLTTGI
                     ERQKELIEGAEGFIYAVAINGVTGKSGNYRADLDKHLAQLHQVADIPVLTGFGVSSQA
                     DLERFNAVSDGVIVGSKIVKALHQGEPIQDFIRQAVAYQK"
     gene            complement(3415..4638)
                     /gene="trpB"
                     /locus_tag="ACL29Z_001895"
     CDS             complement(3415..4638)
                     /gene="trpB"
                     /locus_tag="ACL29Z_001895"
                     /EC_number="4.2.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000331289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004834 - tryptophan synthase activity
                     [Evidence IEA];
                     GO_process: GO:0000162 - tryptophan biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan synthase subunit beta"
                     /protein_id="HGR0070151.1"
                     /translation="MAYQEPNKDGFYGKFGGRFVPETLMTAVLELEKAYRESQADPSF
                     QEELNQLLRQYVGRETPLYYAKNLTQHIGGAKIYLKREDLNHTGAHKINNALGQVWLA
                     KRMGKKKIIAETGAGQHGVATATAAALFNMECTIYMGEEDVKRQALNVFRMELLGAKV
                     EAVTDGSRVLKDAVNAALRSWVANIDDTHYILGSALGPHPFPEIVRDFQSVIGREAKQ
                     QYRDLTGQNLPDALVACVGGGSNAIGLFHPFVEDESVAMYGAEAAGLGVDTEHHAATL
                     TKGRPGVLHGSLMDVLQDAHGQILEAFSISAGLDYPGIGPEHSHYHDIKRASYVPVTD
                     EEALEGFQLLSRVEGIIPALESSHAIAFAVKLAKELGPEKSMIVCLSGRGDKDVVQVK
                     DRLEADAAKKGEAHA"
     gene            complement(4616..5215)
                     /locus_tag="ACL29Z_001896"
     CDS             complement(4616..5215)
                     /locus_tag="ACL29Z_001896"
                     /EC_number="5.3.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000169895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylanthranilate isomerase"
                     /protein_id="HGR0070152.1"
                     /translation="MTKVKICGLSTKEAVETAVSAGADYIGFVFAPSKRQVTLEEVAE
                     LAKLIPADVKKVGVFVSPSRVELLEAIDKVDLDLVQVHGQVADDLFENLPCASIQAVQ
                     VDGNGHVPNSQADYLLFDAPVAGSGQSFDWGQLDTTGLPQSFFIAGGLNEDNVVKAIQ
                     HFTPYAVDVSSGVETDGQKDHEKIRRFIERVKNGISRTK"
     gene            complement(5202..5969)
                     /gene="trpC"
                     /locus_tag="ACL29Z_001897"
     CDS             complement(5202..5969)
                     /gene="trpC"
                     /locus_tag="ACL29Z_001897"
                     /EC_number="4.1.1.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011227478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004425 - indole-3-glycerol-phosphate
                     synthase activity [Evidence IEA];
                     GO_process: GO:0006568 - tryptophan metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="indole-3-glycerol phosphate synthase TrpC"
                     /protein_id="HGR0070153.1"
                     /translation="MSQEFLARILEQKVREVEQMKLEQIQPLRQTYRLAEFLKNHQDR
                     LQVIAEVKKASPSLGDINLDVDIVQQAQTYEENGAVMISVLTDEVFFKGHLDYLREIS
                     SQVEIPTLNKDFIIDEKQIIRARNAGATVILFIVAALSEERLKELYDYATELGLEVLV
                     ETHNLAELEVAHRLGAEIIGVNNRNLTTFEVDLQTSVDLAPYFEEGRYYISESAIFTG
                     QDAERLAPYFNGILVGTALMQAENVAQRIKELQIDKG"
     gene            complement(5966..6970)
                     /gene="trpD"
                     /locus_tag="ACL29Z_001898"
     CDS             complement(5966..6970)
                     /gene="trpD"
                     /locus_tag="ACL29Z_001898"
                     /EC_number="2.4.2.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004048 - anthranilate
                     phosphoribosyltransferase activity [Evidence IEA];
                     GO_process: GO:0000162 - tryptophan biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="anthranilate phosphoribosyltransferase"
                     /protein_id="HGR0070154.1"
                     /translation="MKEIIEKLAKFENLSGVEMTDVIERIVTGRVTEAQIASLLLALK
                     MKGETPEERTAIAQVMRGHAQHIPTEIHDAMDNCGTGGDKSFSFNISTTAAFVLAGGG
                     IHMAKHGNRSISSKSGSADVLEALGINLDLKPAELGKVFDKTGIVFLFAKNMHPAMKY
                     IMPARLELGIPTIMNLTGPLIHPMALETQLLGISRPELLESTAQVLKNMGRKRAIVVA
                     GPEGLDEAGLNGTTKIALLENGEISLSSFTPEDLGMEGYAMEDIRGGNAQENAEILLS
                     VLKNEASPFLETTVLNAGLGFYANGKIDSIKEGVALARQVIARGKALEKLRLLQEYQK
                     "
     gene            complement(6981..7547)
                     /locus_tag="ACL29Z_001899"
     CDS             complement(6981..7547)
                     /locus_tag="ACL29Z_001899"
                     /EC_number="4.1.3.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004049 - anthranilate synthase activity
                     [Evidence IEA];
                     GO_function: GO:0046820 - 4-amino-4-deoxychorismate
                     synthase activity [Evidence IEA];
                     GO_process: GO:0000162 - tryptophan biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aminodeoxychorismate/anthranilate synthase
                     component II"
                     /protein_id="HGR0070155.1"
                     /translation="MILLIDNYDSFTYNLAQYIGNFAEVQVLRNDDSKLYEEAEKADG
                     LVFSPGPGWPVDAGKMEDMIRDFAGKKPILGICLGHQAIAEVFGGKLGLAPKVMHGKQ
                     SNINFEAPSVLYQGIEDGRAVMRYHSILIEEMPEDFEVTARSTDDQAIMGIQHKNLPI
                     YGFQYHPESIGTPDGLSSIRNFIEKVVK"
     gene            complement(7544..8905)
                     /gene="trpE"
                     /locus_tag="ACL29Z_001900"
     CDS             complement(7544..8905)
                     /gene="trpE"
                     /locus_tag="ACL29Z_001900"
                     /EC_number="4.1.3.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004049 - anthranilate synthase activity
                     [Evidence IEA];
                     GO_process: GO:0000162 - tryptophan biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="anthranilate synthase component I"
                     /protein_id="HGR0070156.1"
                     /translation="MERIIHGDVLSPILAYMRLKGQHKVILESIPRDKETARFSILAY
                     NPVFEIKFENGVLYQNGQVIDRDPLDFLYEVIHKSQHHSELPFGGGAIGFVGYDMISL
                     YEEIGQIPEDTIGTPDMHFFVYESYMVFDHKKEKIHVIEDALYSERSQEALEKSLNQV
                     LEELRIPAPNEFEDLDLSPLDFKPHIAPHKFEGMVETARDLIRNGDMFQCVLSQRFSA
                     EVTGNSFDFYRNLRVTNPSNYLYFYDFGDYQIIGASPESLVSVKNGIVTTNPIAGTRP
                     RGATDEEDKALATDLLSDEKETAEHRMLVDLGRNDIGRISETASVQVTKYMEVELFRY
                     VMHLTSVVKGRLLAELTAMDALKATLPAGTVSGAPKIRVMRRIYELETEKRGVYAGAI
                     GYLSATGDMDLAIAIRTMILKNQRAYVQAGAGIVYDSIAQNEYQETINKAKSMTRIGE
                     LRP"
BASE COUNT         2564 a         2219 c         1774 g         2790 t
ORIGIN      
        1 taatgaaaag cttaaaaaga ttaatatcta catttatcca tagcaaaaaa tcataggatt
       61 ttaagaatct gacaactagg aagaaaacta atatgacctt atctaagaaa caattacaac
      121 taagagctaa aatactggaa acagtttaca cattaggtcc catttcacga attgaaatcg
      181 ctactaaaac aggaataaca cctgcaacaa ctagcagtat cacaaatgat ctgattaaag
      241 aaaatattct cttagaactt ggtgaagacg aacacgatac aagcgtagga agaaaaaaaa
      301 tcctgctaga cattcaagct aaacgatttt actacattgg ttgtgaacta tctgaaaaac
      361 atttcacttt tgctttagga gataatctag gaaatatctt aaaggaagag aaagaaattg
      421 ttactaaaca gttaatccaa gaaaagggaa atcaactcat taaccagaca ctaaagcaat
      481 tcttaaataa ctgctctgat tatgaaatag aagcaattgg aatcgcgcta cctggtcgct
      541 atttagatga ttataaaata acaacaaaca atcctttatg gcaacatatc gacttagaaa
      601 tgattcaatc ccactttgat aagcctttgt ttttctctaa caatgttaac tgtatggcta
      661 taggtaaacg cctatttagt cgccaacaga atgaccctaa ttttgcttat tttcattttg
      721 ctagaggtat gcactgttct tatatctacg acggaaacat ttatgggaaa ggaaatctaa
      781 tgattggaga aatagggcat acagttgttt catctgaggg agaagaatgt agttgcgggc
      841 gcaagggatg cttacaaact tttgctggag aatcttggtt aatcaaaaaa tcaaaaattc
      901 tatatcatca atctccctat tctctacttc ctagtttagt caaaaatgcc gatgatattg
      961 atatccaagt tattttaacc gcttatcaat taggtgacac tggaataatc acacttatcc
     1021 atcaagcctt actctatctt agtcaaacca ttttaaatat cagtatgatg attgactctc
     1081 aaaaaatcta cctacatagt cctttactaa caaatcaaca catcatccaa aaactatata
     1141 gtgaaatgaa ctacaaaccc aaactgctct ataatcgcct acctgaagtc attattgaac
     1201 cttacaatga ttttacagcc gcacacttag ctattgcact ttgtttgtat catacaattc
     1261 tacattctta attttctatt acatttaata aataggctaa aaagagggag tatatcataa
     1321 aaagcgaaca aacctgtttt ctgaaaatca gaattctgtt ttgttcgctt tctttatatt
     1381 tggaattata ctcctatctc ccctttttca taatgtatag taaaatgaaa taataacagg
     1441 acgaatcgat cgggacagtc aaatcaattt ctaacaatgt tttagaagta gaggtgtact
     1501 attctagttt caattcacta tattttcgta caggtgcttc aaccatttga acgatttcaa
     1561 atccttcttt ttggtaaaga ttctgagctc tttgatttgc ctcgaagaca tttagagaaa
     1621 tactatctat atcttcattt tcaaaggcca aactaacaaa tttccttaaa gcttggctat
     1681 ctaagccttg cccctgtttc tgggggttga taaaaaatct cccgatatga agattgctgt
     1741 cttctagcct gattttctgg ataagtccca caaactcttg ttcatcaaag attgaaaaga
     1801 ctccttccaa ggcttgaagg gtcagtagaa aaggaatcct tggtcccatc cattgttctt
     1861 gaaaggattt gcctagggag ttggaccact ggcatacaaa ttgagcgttt tctatactca
     1921 ccttttcttc aaaacgaatt gtcatctttt cctccccatc ttatctatgt ttctccatta
     1981 tactacttct cccatttttt acgaatagat aagtatgatt gatatttatt tttttcttgt
     2041 cgggagcatt ctcgcttcct ttcttggttt ggtcattgac cgttttccag agcaatccat
     2101 tatcagttca gccagtcact gcgattcctg tcagactcgc ttgcatccct tagatttgat
     2161 tccgattctc tcacaggtct tcaatcgctt tcgctgtcgc tactgcaaag ttcgctatcc
     2221 tgtctggtat gccctctttg aactaggctt aggactcctc tttctgcttt actcttggga
     2281 attgctttcc ttggggcaag tcgtcctaat caccgctggt ttgaccttgg gtatctacga
     2341 ctttcaccat caggaatatc ccttactggt ctggatgact ttccacctaa tcctaatagc
     2401 ttcctctggc tggaatctgg tcatggtctc cttcctcata cttggaattt tggctcattt
     2461 tatcgatatc cgcatgggtg caggggattt ccttttttta gcttcttgtg ctctcgtctt
     2521 tagcgtaacg gagttactga tcttgattca gttcgcttct gcgacgggta tcctggcctt
     2581 tctcctgcaa aagaaaaagg aaagacttcc tttcgtgcct ttcctcttac ttgctacttg
     2641 tttgattatt tttggtaagc tactgcttgt ctgataaaat cctgaatcgg ctctccttgg
     2701 tggagagctt ttactatttt tgaaccgacg ataacaccat ctgacaccgc attgaagcgt
     2761 tccagatcgg cttgactaga tacaccaaaa cctgtcaaga ctgggatgtc ggccacttga
     2821 tgaagttgcg ccaagtgctt gtccaaatct gcacggtaat tgcctgattt ccctgtcact
     2881 ccattgatgg caacggcata gatgaatccc tccgcccctt caatcaactc tttctggcgc
     2941 tcaattcctg tggtcaagct tactaaagga atcaaggcga tatctgtatc tgccaaaaat
     3001 ggttctacaa agttggcatg ttcatgaggc aagtctggga taatcaagcc cttcacagct
     3061 gtatcagcca gatctttgac aaagttctcc acaccgtact gaaagagggg attgaagtag
     3121 gtcatgatga ccagtggaat ctctgtttca atggttttca aggtttcaac taaagcctgg
     3181 gtagaggtcc cgtgggctaa actgcgcaag ccagcttctt cgataacagg tccatctgca
     3241 acagggtctg aaaagggaat acccacttca attgcagaga cacccaaatc ttctaaaaag
     3301 tgaattgttt cagcaagacc gtccaaacct ttctcgtggt caccagccat gatataggga
     3361 acaaaaattc cttttccagt tgcttttata gcattcaatt tttctgttag tgtcttaggc
     3421 atgagcttct cccttctttg ctgcatctgc ttccaagcgg tctttgactt gaaccacatc
     3481 cttgtcccca cgacctgata ggcagacaat catagacttt tctggtccaa gttctttggc
     3541 caatttcacc gcaaaggcga tagcatggct agattccaag gctgggataa tcccttccac
     3601 acgagacaag agttgaaatc cttccaaagc ttcttcgtct gtcacaggga catagctggc
     3661 acgtttgata tcgtggtagt gagaatgctc tggaccgata ccaggatagt ccaaacctgc
     3721 tgagatagag aaggcttcaa gaatttgacc atgggcatct tggagcacat ccatgaggga
     3781 accgtgaagg acacctggac gacccttggt caaggtagct gcgtggtgct ccgtatccac
     3841 accaagtcca gccgcttcag ctccatacat ggctactgac tcatcttcta caaagggatg
     3901 gaagagaccg atggcattcg acccaccacc aacacaggct actagggcat ctggcagatt
     3961 ttgtcctgtc aagtcacggt actgttgttt agcctctcga ccaatgacac tttggaagtc
     4021 acgaacaatt tctggaaatg gatgaggccc caaggcagaa ccaaggatat agtgggtatc
     4081 atcgatatta gccacccatg aacgaagggc tgcattgacc gcatccttga gcacgcgcga
     4141 accatctgtc acggcctcga ccttagctcc caaaagctcc atacggaaga cattgagggc
     4201 ttggcgtttg acatcttcct cacccatgta gatggtacat tccatgttaa agagggccgc
     4261 agcagttgca gttgccacac cgtgctgacc agcacccgtt tctgcgataa ttttcttttt
     4321 acccatgcgt ttggcaagcc aaacttgtcc taaggcattg ttaatcttgt gggctcctgt
     4381 atggttaagg tcttcccgtt tgagataaat cttggctccg ccgatatgct gggtcaagtt
     4441 ttttgcgtag taaaggggag tttcacgtcc cacgtactgg cgcaaaagtt ggtttaattc
     4501 ctcttggaaa cttgggtctg cctgactttc acggtaggcc ttctccaact ccaaaactgc
     4561 tgtcatcaat gtttctggga caaaacgtcc gccgaatttt ccgtaaaatc catctttatt
     4621 tggttcttga tatgccattc tttaccctct ctataaatct tctaatcttt tcatgatctt
     4681 tttgtccatc tgtctccact ccgcttgata catctactgc atagggagta aagtgttgaa
     4741 ttgcttttac tacattgtct tcattaagcc cacctgcgat aaagaaagac tgaggtaatc
     4801 cagtcgtatc cagttgaccc caatcaaagg actggccact tcctgccaca ggggcatcaa
     4861 agagtagata atctgcctga gaattgggga catgcccatt tccatctacc tgcacagcct
     4921 gaatactggc acaaggcaaa ttctcaaata aatcatctgc cacctgaccg tgaacttgaa
     4981 ccaagtccaa gtcaactttg tcaatcgctt ccagcagttc tacccgactt ggtgaaacaa
     5041 atactccaac ctttttcaca tctgcaggaa taagctttgc caactcagct acctcttcta
     5101 aagtcacctg tcttttacta ggtgcaaaga caaaaccgat atagtcggct cctgctgaaa
     5161 cggctgtttc caccgcttct ttggtcgata gtccacaaat tttaaccttt gtcaatctgc
     5221 aactccttga ttctctgggc cacattttct gcctgcataa gagctgtccc taccaaaatt
     5281 ccgttaaagt atggggctag tcgttccgca tcctgccctg tgaaaatggc agattcagaa
     5341 atgtaatagc gaccttcctc aaagtaaggg gctaaatcta cactggtctg caagtcgacc
     5401 tcaaaggtag tcaagttgcg gttgttgacc ccgataatct cagcaccaag tctgtgggct
     5461 acctctagtt cagctagatt gtgagtctcc actaagactt ccagaccaag ctctgtcgcg
     5521 tagtcataca gttccttgag gcgttcttcg gacaaggctg ccacaatgaa caagataact
     5581 gtcgcacctg cattgcgagc gcggatgatt tgcttttcat cgatgataaa gtctttgttg
     5641 agcgtcggaa tctctacctg actggaaatt tcccgtagat aatccaaatg ccctttaaag
     5701 aaaacctcat ctgtcaacac cgaaatcatc actgctccgt tttcttcata agtctgggcc
     5761 tgttgcacaa tatccacatc gagattgata tctcccaaac tagggctagc tttcttgacc
     5821 tcagcgatta cctgcaagcg gtcctgatga ttcttcaaaa attctgccaa gcgataggtc
     5881 tggcgcagag gctggatttg ctccagcttc atctgctcca cctcacgcac cttctgctct
     5941 aagattcgtg ctaaaaattc ctgactcatt tttggtactc ctgtaacagt ctgagttttt
     6001 caagggcctt gcctctagca atcacttgac gggccaaggc aactccttcc ttgatgctat
     6061 caatcttacc attagcatag aaaccaagac cagcattcaa gactgtcgtt tccaagaatg
     6121 gacttgcttc gtttttcaga acgctaagca aaatttctgc attttcctga gcattcccac
     6181 cacgaatatc ttccatagca tagccttcca ttcccaaatc ctctggagta aagcttgaca
     6241 agctgatttc gccattttca agaagtgcaa tcttggttgt tccgttcaag ccagcttcat
     6301 ccaacccttc tggtccagca accacgatgg cacgtttgcg acccatattt ttcaaaacct
     6361 gagctgtact ttctaggagt tctggacgac taattccaag aagctgtgtt tctaaagcca
     6421 ttggatgaat cagtggacca gtcaagttca taatcgttgg aattcccaat tccaaacgag
     6481 ctggcatgat gtatttcata gctgggtgca tatttttagc gaagagaaag acgattccag
     6541 ttttatcaaa gaccttacct agttcagctg gtttgaggtc aagattgatt cccaaggctt
     6601 cgaggacatc tgcggaacca gatttagaag aaatcgagcg gttaccatgc ttggccatgt
     6661 gaataccgcc accagccaag acaaaggctg cagttgtgga aatattaaaa ctgaaagact
     6721 tgtccccacc tgtaccacag ttgtccatgg catcatgaat ctcagttgga atatgctggg
     6781 catgtcctct catgacttgg gcaatggctg tgcgttcttc aggtgtttcc cccttcatct
     6841 taagagctaa gaggagagaa gcaatctgcg cttcagttac acgcccagtt acgatacgct
     6901 caatgacatc cgtcatttcc acacctgata aattttcaaa ttttgctagt ttttcaataa
     6961 tctctttcat cctagtttcc tcactttaca accttctcga taaaattccg aatagaagac
     7021 aagccgtctg gcgttccaat gctctctgga tggtactgga agccataaat cggtaggttt
     7081 ttatgttgaa tccccatgat ggcttggtca tcagtcgaac gagctgtcac ttcaaagtct
     7141 tctggcattt cctcaatcaa aatactgtga taacgcatga ccgcacggcc atcctcaata
     7201 ccttgataca aaacagatgg cgcttcaaag ttgatattgc tctgtttccc atgcatgact
     7261 tttggagcca aacctagctt accaccaaag acttctgcaa tggcttggtg acccaaacaa
     7321 atccctagaa tcggcttctt gcctgcaaaa tcacgaatca tgtcttccat ctttccagca
     7381 tcaactggcc aaccaggacc aggagaaaag accagaccat ctgctttttc agcttcttca
     7441 tacagcttgg aatcatcatt tctcagaacc tgaacttctg caaaattccc aatgtattgg
     7501 gccaagttat aggtaaaaga atcatagttg tcaatcaata aaatcatggt cttagttctc
     7561 caattctagt catagatttt gctttgttaa tggtttcttg gtattcgttt tgggcgatag
     7621 agtcgtagac aatccctgcc ccagcctgca cataggctct ttgatttttg agaatcatgg
     7681 ttcggatggc gatggccaaa tccatatcac ccgtcgcaga caagtagccg attgccccag
     7741 cgtatactcc ccgtttttcc gtttccagtt catagatacg tctcatcact cgaatctttg
     7801 gcgctccaga aacggttcca gcaggaagcg ttgctttcaa ggcatccatg gcagtgagtt
     7861 ctgcaagcaa acgtcccttg accacactgg tcaaatgcat gacgtagcgg aagagctcca
     7921 cctccatata cttagtaact tggacactgg ccgtttcaga gatgcggcca atatcgttac
     7981 gccccaagtc taccaacatt cgatgttctg ctgtttcctt ctcatcagag aggaggtcag
     8041 tcgccaaggc cttgtcttct tcatccgtag cccctcttgg tcgcgtccct gcaatcggat
     8101 tggttgtcac gatgccattt ttgacagaaa ccaaactttc tggactggct ccgatgattt
     8161 gataatcccc aaaatcatag aaatagaggt aattggatgg attggtcacg cggagatttc
     8221 tgtagaagtc aaatgaattt ccagtaactt ctgctgagaa acgctggctg agtacacatt
     8281 ggaacatatc accattacga atcaagtcac gagctgtttc taccattccc tcaaacttat
     8341 gtggagcgat atgcggtttg aagtcaagtg gtgataaatc caagtcttca aattcatttg
     8401 gagcaggaat gcgtaattcc tcaagcactt ggttcaagga tttttccaag gcctcttgac
     8461 tgcgctcact atagagagca tcctctatga catgtatctt ctccttcttg tggtcaaaga
     8521 ccatatagct ctcatagaca aagaaatgca tgtctggtgt cccaattgta tcctcaggga
     8581 tttgaccaat ttcttcataa agcgaaatca tatcgtaacc cacaaaacca atggctccac
     8641 caccaaaagg tagctctgag tggtgctgac tcttatgaat cacttcataa aggaaatcca
     8701 agggatcccg atcaatcact tgaccatttt gataaagaac tccattttca aacttaatct
     8761 caaaaacagg attataggct aagatagaaa aacgagctgt ttccttgtct ctcggaatac
     8821 tctctaaaat aaccttatgt tgccccttta agcgcatata agccaagatt ggtgataaga
     8881 catctccatg aatgattcgt tccattgtaa tttccctttc agttctactt ctagtccgtg
     8941 gtgactgtat gaaaaatccc cacgcaaaat aacttgcgtg aggacgaaat tcgcggtgcc
     9001 acctcaatta taggatttct cctatctctc attcctgtct cagatatctc ctgtaacagg
     9061 ctgtgcgata aagggcactc ccttgagaat gatgttttct tctctcgttt cagatgaacc
     9121 caactttaca gctttctctg cttgttttca gcaaccacaa gctctctgtg agagaaagag
     9181 ctgtaatttt tccatctatt attttttagc ttctagtaat ctgcaatcgc agctaggtcc
     9241 ttgcctccac gaccagagac attgatgaag agatgttcat ctcggtacac ctttatactc
     9301 ttcgaaaatc tcttcaaacc gcgtcaacgt cgccttatcg taggtat
//
LOCUS       DBEJAU010000068         8998 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC323 isolate 683620
            SAMN38261939-rid24807223.denovo.068, whole genome shotgun sequence.
ACCESSION   DBEJAU010000068 DBEJAU010000000
VERSION     DBEJAU010000068.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261939
            Sequence Read Archive: SRR26833919
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 8998)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8998)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576303.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576303.1
            Genome Coverage       :: 154x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/19/2025 01:05:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,121
            CDSs (total)                      :: 2,078
            Genes (coding)                    :: 1,943
            CDSs (with protein)               :: 1,943
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 36
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 72 of 135
            Pseudo Genes (incomplete)         :: 63 of 135
            Pseudo Genes (internal stop)      :: 51 of 135
            Pseudo Genes (multiple problems)  :: 46 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8998
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261939-rid24807223.denovo.068"
                     /strain="GPSC323"
                     /isolate="683620"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            88..672
                     /locus_tag="ACL29Z_001901"
                     /pseudo
     CDS             88..672
                     /locus_tag="ACL29Z_001901"
                     /inference="COORDINATES: protein motif:HMM:NF021048.4"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ApaLI family restriction endonuclease"
     gene            669..1859
                     /locus_tag="ACL29Z_001902"
     CDS             669..1859
                     /locus_tag="ACL29Z_001902"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific DNA-methyltransferase"
                     /protein_id="HGR0070157.1"
                     /translation="MTVLKGDNLEILKTIESSSIDLIYMDPPFFTQKTQKLSNNKNIM
                     YSFEDTWTSIEDYKEFLSVRLEECKRVLKNSGSIFVHCDKIANHHIRLILDNIFGADM
                     FQSEIIWNYKRWSNSKKGLLNNHQNIYFYSKSKDFKFNTIFTEYSSTTNIDQILVERK
                     RDGNSKTIYKVDNNGNYILAKEKNGVPLSDVWNIPFLNPKAKERVGYPTQKPILLLEQ
                     IIKIATDKNDIVLDPFCGSGTTLVASKILNRNYMGIDLSEEAINITQQRLENVIKTSS
                     NLLNKGIEAYRTKTEEEENILKLLQAKIVQRNKGIDGFLPKHFQKKPIPIKIQKNNEC
                     LNESISLLQNAINSKKLDFGVVIKTHSDNLLFDFDTIPENIIVVDHFELTIEKWLSKS
                     QQLL"
     gene            complement(2369..3361)
                     /locus_tag="ACL29Z_001903"
     CDS             complement(2369..3361)
                     /locus_tag="ACL29Z_001903"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000122906.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0043565 - sequence-specific DNA binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HGR0070158.1"
                     /translation="MSYYDFVKDYMKVDECKNNEKYSSAGHTFCWKKENSTYAEGLYW
                     FYEGGSFIIDIHDFYIKEEVVQNSTYSMSDYVSIYSSYIVSANGEKFNPYQTITANSL
                     CTFDFDNIKDDFVFLLHENCCYLAVSIGFKKELIEKHLASININPESFYSTLLQPNQI
                     ILTKALERVAMEILNCKMDAPAADFFFKAKANEWISIVIDTYLNRKKYKIEIDDDKAL
                     EDVARFLDDHFATNVNQGTLEKISKMSGTKLKNLFKEKYCQSITEYTQRKRMNVAETL
                     LLNTELPIKEIAESVGYSSASKFSIYYKRYKGKLPSEVRNLACKHHNFKCDYCD"
     gene            3521..5269
                     /locus_tag="ACL29Z_001904"
     CDS             3521..5269
                     /locus_tag="ACL29Z_001904"
                     /EC_number="7.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGR0070159.1"
                     /translation="MKIYKKLFAYVQDKKYLGVLAIIFSAISALLTVYGYYLIYKFLD
                     KLIINSNLSGAESIALKSVITLTSGAIFYFVSGMFSHILGFRLETNLRKRGIDGLEKA
                     SFRFFDLNPSGQIRKIIDDNAAQTHQVVAHMIPDSSQAIITPVLALGFIVSIRVGIIL
                     LALTIIGGLILGAMMGEQEFMKIYQESLSKLSAETVEYVRGMQVVKIFKANVESFKSF
                     YKAIKDYSKYAYDYSLSCKRPYVLYQWLFFGLIAILIIPIVYFMTSLASAKVILLELI
                     MILFLSGVLFVSFMRMMWYSMYISQGNYAVDTLEALYEDMQKDKLVHGNVNNFKNYNI
                     EFENVSFAYNDKAVIENLSFNLEEGKSYALVGSSGSGKSTVAKLISGFYNVNKGSIKI
                     GGIAISEYSDEALIKAISFVFQDSKLFKKSIYDNVALANKDATKDDVMRALKLAGCDL
                     ILDKFPERENTIIGSKGVYLSGGEKQRIAIARAILKDSKIIIMDEASASIDPDNEFEL
                     QKAFKNLMKDKTVIMIAHRLSTIKDLDEIIVMDSGKIIERGSDKELMSKDTRYKSLQE
                     MFNSANEWRVSNERVL"
     gene            5253..6974
                     /locus_tag="ACL29Z_001905"
     CDS             5253..6974
                     /locus_tag="ACL29Z_001905"
                     /EC_number="7.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019214631.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGR0070160.1"
                     /translation="MKEFYKKRFALTDGGARNLSKATLASFFVYCINMLPAILLMIFA
                     QEVLENMGKSNGFYIVFSVLTLIAMYILLSIEYDKLYNTTYQESADLRIRTAENLSKL
                     PLSYFSKHDISDISQTIMADIEGIEHAMSHSIPKVGGMVLFFPLISVMMLAGNVKMGL
                     AVIIPSILSFIFIPLSKKYQVNGQNRYYDVLRKNSESFQENIEMQMEIKAYNLSKDIK
                     DDLYKKMEDSERVHLKAEVTTILTLSISSIFSFISLAVVIFVGVNLIINKEINSLYLI
                     GYLLAAMKIKDSLDASKEGLMEIFYLSPKIERLKEIQNQDLQEGDDYSLKKFDIDLKD
                     VEFAYNKDAKVLNGVSFKAKQGEVTALVGASGCGKTTILKLISRLYDYDKGQILIDGK
                     DIKEISTESLFDKVSIVFQDVVLFNQSVMENIRIGKQDASDEEVKRAAKLANCTDFIE
                     KMDKGFDTVIGENGAELSGGERQRLSIARAFLKDAPILILDEITASLDVNNEKKIQES
                     LNNLVKDKTVVIISHRMKSIENADKIVVLQNGRVESEGKHEELLQKSKIYKNLIEKTK
                     MAEEFIY"
     gene            6985..7569
                     /locus_tag="ACL29Z_001906"
     CDS             6985..7569
                     /locus_tag="ACL29Z_001906"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000368966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MptD family putative ECF transporter S
                     component"
                     /protein_id="HGR0070161.1"
                     /translation="MDNKKLKVKDLVSIGVFGVIYFAFMFGVGMMGLIPILFLIYPTV
                     LAIVAGTVVMLFMAKVQKPWALFIFGMISPLVMFAAGHTYVVVVLSLIVMIIAELIRK
                     IGNYNSFKYNMLSYAIFSTWICSSLMQMLLAKEKYMEWSLMTMGKDYVDVLEKLITYP
                     HMALVALGAFLGGILGAYIGKALLKKHFEKAGIV"
     gene            7569..8264
                     /locus_tag="ACL29Z_001907"
     CDS             7569..8264
                     /locus_tag="ACL29Z_001907"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001141947.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter transmembrane
                     protein EcfT"
                     /protein_id="HGR0070162.1"
                     /translation="MPTFSSNAPFNPNPISKILVVFITGLTVMHSINIRFELAIVCLI
                     GILLYLNGYKKTLFKWIILCGILYSLPNFMVLSELNPIVKMFLSIPIVIRMFILPFMA
                     ASFMIKTSDVGAIISSMDKLKISKNVSIPIAVMFRFFPSFKEEKKNIKMAMRVRGINF
                     KNPVKYLEYVSVPLLIISSNISDDIAKAAETKAIENPIAKTRYIRVKIQLIDFVYVLA
                     VVGLIVGGLIWLK"
     gene            8252..>8998
                     /locus_tag="ACL29Z_001908"
     CDS             8252..>8998
                     /locus_tag="ACL29Z_001908"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002837029.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGR0070163.1"
                     /translation="MVEIKNLSLDYGEEHILDDISLSIAEGECVLFTGKSGNGKSSLI
                     NSINGLAVRYDNAKTKVEIIIDGKNIKNLELYQISMLVSTVFQNPKTYFFNVNTTLEL
                     LFYLENIGLAREEMDRRLKDMLEIFPIKNLLNRNIFNLSGGEKQILCIAASYIAGTKI
                     IVMDEPSSNLDIKSISVLAKMLKILKEKGISIIVAEHRIYYLMDIVDRVFLIDKGKLK
                     KTYTRSEFLKLDKNELNALSLRDKELSKLKV"
BASE COUNT         3320 a         1214 c         1529 g         2935 t
ORIGIN      
        1 attttattta taacaagagg atagaaatga ccgaattaga aagaaaaaat cgaaaaatta
       61 gctaagaaat actctgataa cttaaacatc aaagttcaag agagagttcg tgaaatggca
      121 aatgataata agagccatta tttgatatac agagttttag gtatttcatt tgaagaagga
      181 gaaaatatcg atttgtatca aaataaaggt cgttttttat acaaatatgc tggttcattt
      241 ttagaagaag ctgcagtact atcctttaac gaaaaatttg gtacagaaaa tacttaaaaa
      301 gttaacattc ctaattctga aagtacaaaa cctaagactt ttgaaattga ttgtttagtc
      361 ggagaaaaac acgcatacga aataaaatgg tgggatgcaa ctacagatgg agaccatata
      421 actaaagaac acactagaat aaaagttatt cataacaaag gatatatacc aattcggtta
      481 atgttctact atccaaatag aactcaagcc ataaaaattc agcaaacttt agaaacattg
      541 tataacggta ttggagggaa atattattat ggagattctg cctgggaaca tttaagagca
      601 gtgaccggta ttgatttact tagtattcta acagatattg caaataaaaa aacaggggta
      661 aaatcaaaat gacagtatta aaaggagata acttagaaat attaaaaact attgaatcct
      721 caagtattga tttaatctat atggaccctc ctttctttac acagaaaacc caaaaattat
      781 ctaataacaa aaatattatg tattcattcg aagatacgtg gacttcgatt gaggattaca
      841 aagaattttt gtctgtaaga ttagaagaat gcaaaagagt gctaaaaaat agtggcagta
      901 ttttcgttca ttgtgataaa attgcaaatc atcatattag attaatttta gataatatct
      961 ttggagcaga tatgtttcaa agcgaaatta tatggaacta taaacggtgg tctaattcaa
     1021 aaaagggatt attgaacaat catcaaaaca tttactttta ttcaaagtca aaagatttta
     1081 aatttaatac aatttttaca gagtattctt ctactacaaa tatcgaccaa atactagtgg
     1141 aacgaaaacg agatggaaac tctaaaacta tatataaggt tgataataat ggtaactata
     1201 ttctagcaaa agagaaaaat ggagttcccc tttcagatgt ttggaatata ccatttctta
     1261 atccaaaagc taaagaaaga gtaggttatc ctacacaaaa acctattctg ttattagaac
     1321 aaattataaa gattgctact gataaaaatg atatagtttt agacccgttc tgtggaagtg
     1381 gaactacttt agtagcctcc aagattttga atagaaatta tatggggatt gatttatctg
     1441 aggaagctat caatataact cagcaacgtc tggaaaatgt tataaaaaca agttcaaatt
     1501 tattgaataa aggaatcgaa gcatatagaa ccaaaactga ggaagaggaa aacattctta
     1561 aattattaca ggcaaaaatt gttcaaagaa ataaaggaat tgatggtttt ttacctaaac
     1621 attttcaaaa aaaaccgata cctataaaaa ttcaaaaaaa taatgaatgt ctgaatgaga
     1681 gtatctcttt attacagaat gctataaact ccaaaaaact tgattttgga gtagttataa
     1741 aaactcattc agataattta ttatttgatt ttgatacgat tcctgaaaat ataatagtag
     1801 ttgaccattt tgaacttaca atcgaaaaat ggttaagtaa aagtcaacag ttactatagt
     1861 ttgcaaatta tttacagaaa gaacaaaaaa tgctctgaaa cactgatttc aaagcatttt
     1921 ttgttagttt aaaattactc ccattcttct tttccaaacg tacaatatat ccaaaaccat
     1981 tcaaaatact agattctatt ttttataata tcactaaatc cacctaatta taggacgttt
     2041 tcagattttt agtcccagtc ccagtaccgg agaaatattg ttttaatata atatctcttt
     2101 ttgtcttcta agctcttaaa agcaaaagaa caagtaaaga gtcaagacaa ggataaaaag
     2161 tccatattag ggcaaataaa aagctttaag acagatgaca aatctaagtc aaataagaaa
     2221 gaccatagca aaggtgcaga gagataaata ttggcggtct tcggactgcc tttatttttt
     2281 tatccatttt tcaaatcaaa tttattcaga ctatatatgc acatatacac ttaaattcat
     2341 ataaaaacat ggcttgtaaa aaattacttt aatcacaata atcgcattta aaattgtgat
     2401 gtttgcaagc taaattacgg acttcacttg gaagttttcc cttgtatctt ttataataga
     2461 tagaaaattt gctggcagat gaatatccaa cagattctgc tatctctttt ataggtagtt
     2521 cagtgtttaa aagaagagtt tcagctacat tcattctttt tctttgagtg tactctgtaa
     2581 tgctttgaca atatttttcc ttaaataaat tttttaattt agtaccactc attttagata
     2641 ttttttcaag cgtgccttga tttacattcg ttgcaaaatg atcatctaag aatcttgcta
     2701 catcttcaag tgctttatca tcatcaattt caattttata tttttttcta tttaagtatg
     2761 tgtcaattac tatacttatc cattcatttg cctttgcttt aaagaaaaaa tcagcggcag
     2821 gagcgtccat cttacaattt aatatttcca ttgccactct ttctaaggcc tttgtaagta
     2881 ttatttgatt cggttgaagc aaggttgaat aaaaagattc tggattaatg ttaatagatg
     2941 ctaaatgttt ttctattagc tcttttttaa aaccaatgga aacagcaaga taacaacaat
     3001 tctcgtgtaa taaaaaaaca aaatcatctt ttatattatc aaaatcaaaa gtacatagag
     3061 agtttgcggt aatagtttga tacggattaa acttttctcc gtttgcactg acaatgtaac
     3121 ttgaataaat tgaaacatag tctgacatac tataagtgct attttgaact acttcctctt
     3181 tgatataaaa atcatgtata tcgataatga agctgcctcc ttcataaaac caatatagtc
     3241 cttctgcata agttgaattc tcttttttcc aacaaaatgt atgacctgca cttgaatact
     3301 tctcattgtt tttacattca tctactttca tataatcttt tacaaaatca taatatgaca
     3361 taacacacta tcccttttag acaatattcc aattagcctt attaattcaa aactattgta
     3421 ttagtaatta taacagatgt ataatagaaa agcaatgata gatattatca attaagcgaa
     3481 tttatatcta aaagggatat taaagaaagg agatatgctt atgaagattt acaaaaaact
     3541 atttgcttat gtccaagata agaaatatct tggggttttg gccataattt tttctgctat
     3601 atctgctcta cttacagtat atggatatta tttaatctac aaatttctag ataagttaat
     3661 aattaattca aacttatccg gtgcagagag tatagcatta aaatctgtta ttacactaac
     3721 aagtggagcg atattttatt ttgtctcagg aatgttttca catatcttgg gatttaggct
     3781 tgaaacaaat ttaagaaaaa ggggaatcga tggtctggaa aaagcaagtt ttaggttctt
     3841 tgacttaaat ccatctggtc aaataagaaa gatcatagat gataatgcag cacaaactca
     3901 tcaggtggta gcacacatga ttcccgatag ttctcaggca ataatcacac ccgtacttgc
     3961 acttggcttt atagtaagta taagggttgg cataattttg cttgctctta ctataattgg
     4021 tggcttaatt ttaggggcaa tgatgggcga gcaagaattt atgaagatat accaagaatc
     4081 cctatctaaa ctaagtgctg aaactgttga gtacgtgaga ggaatgcaag ttgtaaaaat
     4141 atttaaagca aatgtagagt cttttaaaag cttttataag gcgataaaag attactcaaa
     4201 gtatgcttat gattattccc tatcttgtaa aaggccttat gttttgtatc aatggttatt
     4261 ttttggactg attgcaattt taattattcc tatagtttat tttatgacta gcttagctag
     4321 cgcaaaggtg attttacttg agcttatcat gattttattt ttatcaggag ttctctttgt
     4381 ttcattcatg agaatgatgt ggtactccat gtatatttct caaggaaatt atgcagtaga
     4441 tactttagag gcgctttacg aagatatgca aaaagacaaa ttagtgcatg gtaatgtcaa
     4501 taattttaaa aactataata tagaatttga gaatgttagc tttgcttata atgataaagc
     4561 tgtcattgaa aatttatcct ttaatttaga agaaggaaag tcctacgcac ttgtcggttc
     4621 atctggatca ggcaaatcaa cagtagcaaa acttatatca ggtttttaca atgttaataa
     4681 aggaagcata aagataggcg ggatagcaat aagtgaatat tctgacgaag ccttaattaa
     4741 agccatttcc tttgtttttc aagattcaaa attattcaag aagagcattt atgataatgt
     4801 agctttagct aataaagatg cgacgaaaga tgacgttatg agagccttaa aattagcagg
     4861 atgcgattta atattagaca aattcccaga aagagaaaat acaatcatag gctcaaaagg
     4921 tgtttattta tccggtggag aaaaacaaag aattgcaatt gctagagcaa ttttaaagga
     4981 ttccaaaatt attattatgg atgaagcatc agcatctatt gacccagata acgagtttga
     5041 attgcaaaaa gcttttaaaa atcttatgaa ggataaaaca gttatcatga ttgcacacag
     5101 gctatctaca attaaagacc ttgatgaaat tattgtcatg gatagtggaa aaattataga
     5161 aagagggtct gacaaagaat taatgtcaaa agatacaagg tataagagcc tgcaagagat
     5221 gtttaacagt gcgaatgaat ggagggtttc aaatgaaaga gttttataaa aaaagatttg
     5281 ctcttacaga tggaggagca agaaatttaa gtaaagcaac actggcttca tttttcgttt
     5341 attgtataaa catgcttcct gccatattac ttatgatttt tgctcaggaa gttttggaaa
     5401 atatgggcaa aagcaatggc ttttatatag tattctcagt tttgactttg atagcaatgt
     5461 atattttgct ttctatcgaa tacgataaat tatataacac aacctatcaa gaaagtgcag
     5521 atttaagaat aaggacagcg gagaatttat caaaattacc tctatcttac ttttctaaac
     5581 atgacatttc cgacatttca caaacaatca tggctgatat tgaaggcata gagcatgcaa
     5641 tgagccactc aataccaaag gtgggcggca tggtactgtt tttcccatta atatctgtaa
     5701 tgatgctagc gggcaatgtc aagatgggtt tagctgtaat tattccatct attttaagct
     5761 ttatatttat acctttatct aaaaaatatc aggttaatgg acagaataga tattatgatg
     5821 tcttaagaaa aaactcagaa agctttcaag aaaatatcga aatgcaaatg gagattaaag
     5881 catataattt atcgaaggat attaaagatg acttatataa aaaaatggaa gatagtgaga
     5941 gagtacactt aaaggcggaa gtaactacaa ttttaacttt gtctatatct tcaatattta
     6001 gctttatatc tcttgctgtt gtgatatttg tcggcgtaaa tctaattatt aataaagaga
     6061 taaattctct ctaccttata ggatatttac tagctgctat gaagataaaa gactctttag
     6121 atgcatctaa agagggcttg atggaaatat tttatttatc gcccaaaata gaaagattaa
     6181 aagaaattca aaatcaagat ctacaagaag gcgatgacta tagcttaaaa aaatttgata
     6241 ttgatctaaa agatgttgag tttgcctaca ataaagacgc aaaagtttta aatggtgtaa
     6301 gttttaaagc taagcaggga gaggtcactg ctttggtagg tgcaagtggc tgcggtaaaa
     6361 caactatctt gaaacttata tcaagacttt atgattatga caagggacaa atcttaatcg
     6421 atggcaaaga tataaaagaa atatcaacag aatctctttt tgataaggtc tctatagttt
     6481 tccaagatgt ggttctcttt aatcaaagcg ttatggaaaa tattagaatc ggaaagcaag
     6541 atgcaagtga cgaagaggtt aaaagagcag caaaacttgc aaattgcaca gattttatag
     6601 aaaaaatgga taaaggtttc gatacagtta ttggtgagaa cggagctgag ctatcaggag
     6661 gagaaagaca aagattatca atagccagag ccttcttaaa agatgcgccg atattgatct
     6721 tagatgagat aacagcaagc cttgatgtta acaacgagaa aaagattcaa gagtctttaa
     6781 ataatttagt taaagataaa actgttgtaa tcatttcaca tagaatgaaa tccatagaaa
     6841 atgcagacaa gatagtagtt cttcaaaacg gaagagtaga aagcgaaggt aagcatgaag
     6901 agcttttaca aaaatcaaaa atttacaaaa atttaataga aaagacaaaa atggcagaag
     6961 aatttattta ttaggaggac tacaatggat aataaaaaat taaaagtaaa agatttagta
     7021 agcatcggtg tttttggcgt aatttatttt gccttcatgt ttggagttgg tatgatgggc
     7081 ttgattccaa tattgttctt aatatacccg acagtattag ccatagttgc aggaactgtt
     7141 gttatgttat ttatggctaa ggttcaaaag ccatgggcac tatttatatt tggtatgata
     7201 tcaccacttg tgatgtttgc agctggtcat acctacgtag ttgtggtttt atcacttata
     7261 gtaatgataa tagcagaatt aattagaaag attggtaatt ataattcatt taaatacaat
     7321 atgctttctt atgcaatctt cagcacatgg atatgtagct ctttaatgca aatgctttta
     7381 gcaaaagaaa aatatatgga gtggtctttg atgacgatgg gaaaagatta tgttgatgta
     7441 ttagaaaagt taataactta tcctcacatg gctttagtag ccttaggtgc tttcttagga
     7501 ggaattcttg gagcatatat aggcaaggct ctattgaaaa aacactttga aaaagcaggc
     7561 attgtataat gcctactttt tcttcaaatg ctccctttaa tcccaatccg atctctaaga
     7621 tattagtcgt atttatcaca ggcttaactg ttatgcatag cataaacatc cgttttgagc
     7681 tggcaattgt ttgtcttatt ggtattttgc tttatttgaa tggatacaaa aaaacacttt
     7741 tcaaatggat tatattgtgt gggatacttt actccttgcc taattttatg gtgttatctg
     7801 aattaaaccc tatagttaag atgtttttga gtatacctat tgttattaga atgtttattt
     7861 taccatttat ggcagcaagc tttatgataa agacctcgga tgtaggcgca ataatttcat
     7921 cgatggataa gcttaagatt tcaaagaatg tatccatacc tattgcggtt atgtttagat
     7981 tcttcccatc ttttaaggag gagaagaaaa acatcaaaat ggctatgaga gtaagaggga
     8041 taaattttaa aaacccagtc aaatatcttg aatatgtttc tgtgccacta ctcattatat
     8101 catctaatat atcagatgac attgcaaaag cggcagaaac aaaggcaata gaaaatccaa
     8161 ttgccaagac cagatacatt cgcgtaaaga tacagctaat tgattttgtt tatgttttag
     8221 cggttgttgg acttattgtg ggaggcttaa tatggttgaa ataaaaaatt taagtcttga
     8281 ttatggtgaa gagcatatat tagatgatat atcactatcc atagccgagg gagagtgcgt
     8341 gctatttaca ggaaaaagtg gaaatggtaa gtcatcttta ataaattcaa tcaatggact
     8401 agctgtaagg tatgataacg caaagacaaa ggtcgaaata attattgatg gtaagaatat
     8461 aaaaaatttg gaactttatc aaatctcaat gcttgtttca actgtttttc aaaatcctaa
     8521 gacatatttt tttaatgtca atacgacatt agaattatta ttttatttgg aaaatatcgg
     8581 tcttgcaaga gaagagatgg acaggcgttt gaaggatatg cttgagatat tcccgataaa
     8641 aaatcttttg aacagaaata tatttaatct atccggcggt gaaaaacaaa ttctttgcat
     8701 tgcagcttct tatatagcag gtacaaagat tatagttatg gatgagcctt catcgaattt
     8761 agatattaaa agcataagtg ttttggcaaa gatgctaaag atattaaaag agaaaggcat
     8821 aagcataatt gttgcagagc atagaattta ttatttgatg gacatagttg accgtgtatt
     8881 tttaatagat aaaggaaagc ttaaaaaaac ttatactaga agtgaatttt taaagctaga
     8941 taaaaatgaa ttaaatgctt taagtttaag agataaagaa ttaagtaaat taaaagtt
//
LOCUS       DBEJAU010000069         8922 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC323 isolate 683620
            SAMN38261939-rid24807223.denovo.069, whole genome shotgun sequence.
ACCESSION   DBEJAU010000069 DBEJAU010000000
VERSION     DBEJAU010000069.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261939
            Sequence Read Archive: SRR26833919
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 8922)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8922)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576303.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576303.1
            Genome Coverage       :: 154x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/19/2025 01:05:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,121
            CDSs (total)                      :: 2,078
            Genes (coding)                    :: 1,943
            CDSs (with protein)               :: 1,943
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 36
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 72 of 135
            Pseudo Genes (incomplete)         :: 63 of 135
            Pseudo Genes (internal stop)      :: 51 of 135
            Pseudo Genes (multiple problems)  :: 46 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8922
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261939-rid24807223.denovo.069"
                     /strain="GPSC323"
                     /isolate="683620"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            227..1285
                     /locus_tag="ACL29Z_001909"
     CDS             227..1285
                     /locus_tag="ACL29Z_001909"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001849785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0070164.1"
                     /translation="MKDDQKYLLAGLYSLLVAIFYFPLIDSKGIFVSILMAVLLLYLI
                     YFIATVIHIVIIKFIRKKSFKYLVLYPFTYDGSWRFQPINLLYFPEMVRDVIPINLVQ
                     EYCQGQPYGLLKKMLKRIRLSREIALLLATIIVYFFTHRILPLSVFTFMFSYILLFVQ
                     SYLGSNTAWIGNRRLIIDDEFEKILLSKSYVKEISSARYSEYLTCEYKNLTPIILIAI
                     FENLLDSYLLQNQSEVDLDIFYKVLPLLYKEKYTMGFNYFVSLNYLLYKVGFLGIIYD
                     NEALRDLSKQYLNKNISELQDGSFEGGIQDAVASKQIVVINEFIACLNSKCMPSQYDR
                     FFYKDRPYIFSRKSSIKG"
     gene            1600..2577
                     /locus_tag="ACL29Z_001910"
     CDS             1600..2577
                     /locus_tag="ACL29Z_001910"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001837003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0070165.1"
                     /translation="MKNKRYFFDTILMILLLISTIFCVSPVFIKLDILGTPSHAILTF
                     VLAIPLFYILSQCLHTLLLLVSSIFCKLRPIYFHFIFVIIIGARKYYRILFHQLMGFS
                     PGVAVFYKESQTTKNLFKFYYFLYFTTLISHYFFFTFVYDKPLLLPLIPFSIIIALVQ
                     KLYRIENQQLFLLKSKVLTILESKKNCEFNLQDYHEIWKLQSKSELPCVALSYISLIK
                     PYLSESVREQIDLLEVKRFKKINHPISLYGMLDVIKLNLYLRHYNEKNKYESMLKKIL
                     EVRPDFVLIEQNIDDSLNSSQPLSLSLAISEIQLLLEVYMGIKHVSIRR"
     gene            2954..3328
                     /locus_tag="ACL29Z_001911"
     CDS             2954..3328
                     /locus_tag="ACL29Z_001911"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000424474.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPH_0224 family bacteriocin-like peptide"
                     /protein_id="HGR0070166.1"
                     /translation="MELVLPNNYVVLEQEEMMYLDGGFSIPRWPVATAINIAFNGVLG
                     GGAISLVRNYIRNYGLRRVTSAIAGAAARYVGVRVANRVAGFALSAINGFAAWMSIGN
                     AITTIWANNDVNRRDPNLNALW"
     gene            3335..3517
                     /locus_tag="ACL29Z_001912"
     CDS             3335..3517
                     /locus_tag="ACL29Z_001912"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000511668.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0070167.1"
                     /translation="MGIKMEKIFVIIFFVCLFISSITFLAYDFVSEEIKKLIIWINVV
                     FLILIIAMIIYPKLRK"
     gene            3536..4438
                     /locus_tag="ACL29Z_001913"
     CDS             3536..4438
                     /locus_tag="ACL29Z_001913"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000619809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0070168.1"
                     /translation="MIRKLIIFLLMLPLFVLWLELHLLVSNLQLNLEIPFDFVVSTSL
                     TFFVLILSKIVLDILYALKDLYKKEALITIFPFIFIGRKKVNVRFSPYFSFHRKSLSP
                     DDLRSRIIWSFILEIAIILVFILKIPFAIIMLTTIFFWTIMDINHLVFNKTEFLFNQN
                     KWQKEDSFESDLTKTLKDKIQKSELSYSDLMSLLLYDAMNQSTFLTDSELFEDILKKI
                     EDSHNTLLCTGLVELLLYEISISKNHNWSEKIDKIRIELIKINQLDFFYYTSWLRQNF
                     DFCMNREYHKMKSRKLLLSNKKIV"
     gene            4494..4847
                     /locus_tag="ACL29Z_001914"
     CDS             4494..4847
                     /locus_tag="ACL29Z_001914"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000424445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="argininosuccinate lyase"
                     /protein_id="HGR0070169.1"
                     /translation="MELVLPNNYVVIDEEVMMYLDGGAYLSKRACQGICAALAMSSGT
                     FIALAGAAVLTKKLINYIKFGGLGGWLIGAAAGVLATAAGKIAYCIGYGVLNRGCDIN
                     GNPYPWDGFISATVR"
     gene            4844..5572
                     /locus_tag="ACL29Z_001915"
     CDS             4844..5572
                     /locus_tag="ACL29Z_001915"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0070170.1"
                     /translation="MSNVDKIRKIHIIVCWVYIFLSFRAIINDTEYFLLIFLAFIYSI
                     VSLPLYSVKNKIVSICLAINSILLISFPILINKFFPESFLTYTVLISVFITELIIFHL
                     IGKDFDTKLTNEYKKISQFRSKVSQSPWIKYLEISSFILTIFPSILYGTVDNHVLTLI
                     FLIKICVDTTIKFLFIRLFDTSTLMKRRIFFLFALDVIAYLFLGYLLVIQKAGYLFSI
                     LLLFSNFSVPFIKEKEYELFKNSK"
     gene            6051..6248
                     /locus_tag="ACL29Z_001916"
     CDS             6051..6248
                     /locus_tag="ACL29Z_001916"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000680087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0070171.1"
                     /translation="MKHFFAGIGEIKLVGYLLYICVGLAPLFHIYVIGSELSFVKIVL
                     SILGVIFVSMLTIARIYRTFL"
     gene            complement(6448..7311)
                     /locus_tag="ACL29Z_001917"
     CDS             complement(6448..7311)
                     /locus_tag="ACL29Z_001917"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001268159.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HGR0070172.1"
                     /translation="MRYDFGKVYKEIRESKGLTQEEVCGGVLSRTSLSKIESGKTTPK
                     YENMEFLLRQINMSFEEFEYICQLYQPSQRTEIMQTYLNMRSIIGTSDLVNLFQKCQD
                     YLKTHHDLPIEEIRDMLEVVIYLRQHGAGELSDHAEQVVKKLWRKIEKQDTWYESDLK
                     ILNTILFSFPIEYLHLITGKILQRLEVYKNYQHLYDLRIAILLNLSTLYLYNQDKNMC
                     KQICYTLLEDAKNKKSYDRLAICYVRIGICTDDSKLIQKGFSLLDLTEETSMLSHLKK
                     EVETHYQPKKL"
     gene            7777..8115
                     /locus_tag="ACL29Z_001918"
     CDS             7777..8115
                     /locus_tag="ACL29Z_001918"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000915343.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008233 - peptidase activity [Evidence
                     IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine peptidase family C39 domain-containing
                     protein"
                     /protein_id="HGR0070173.1"
                     /translation="MLKKYPCTMQHDQSDCAAAVVSTVLLSYKKELSIMKIREIIGTD
                     MYGTTVSGIVSGLNKLNFTVKAVRVALEDLTPKLTFPAILQVKNDLGQNHFVVLHSIK
                     EKINGTRITK"
     gene            8144..8587
                     /locus_tag="ACL29Z_001919"
     CDS             8144..8587
                     /locus_tag="ACL29Z_001919"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000280367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0070174.1"
                     /translation="MYLDGGAYLSKSACQGICAALAMSPGTFIALTGAAVLTKKLINY
                     IKVGGLGGWLIGAAAGVLALIFLIKICVDTTIKVLLNRIFKASKVMKRRIFSLFVLDL
                     MVYIFLGYVLVIQKDVYLFSILIIFSNFSVPFIREKEYELFKNKK"
     gene            8741..>8922
                     /locus_tag="ACL29Z_001920"
     CDS             8741..>8922
                     /locus_tag="ACL29Z_001920"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000973716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0070175.1"
                     /translation="MLIVLISVIVALLYHKITEYVNNRKIDIVIFLSLLISHFIWNYY
                     FLPIEILIAISGANLL"
BASE COUNT         2915 a         1147 c         1640 g         3220 t
ORIGIN      
        1 gctcttggta tgatattggc attaattttg gtattatcaa gagtgtatag aaaatatttt
       61 tatagagacg atgatgacta aagtttttat caataatttg ggctccttgt caactgtagt
      121 gggttgaaga aaagctaacg tctggggaag gggttaaagc tttgctttat caaatattgc
      181 tttatagaaa gtcctctgtg ggattgaaaa tgataaggtg ttttgaatga aagatgatca
      241 gaaatattta ttagcgggac tttattcgct tctagttgca atattttatt ttccattgat
      301 tgattccaag gggatttttg taagtatatt gatggcggtt ttacttttat atttaatata
      361 cttcattgca acagtcattc atattgtgat aattaagttt ataagaaaaa aatcttttaa
      421 gtatttggtt ctatatccat ttacttatga tgggagctgg agatttcaac ctataaactt
      481 actctacttt ccagaaatgg tgagagatgt cattccgatt aatttagttc aagaatattg
      541 ccaaggacaa ccttacggac tgttaaaaaa gatgctgaaa agaattcgat tgtcacgaga
      601 gatagcttta ctcctggcta ccattatcgt ctattttttt acgcatagaa ttctacctct
      661 ttcagtattt acgttcatgt tctcttacat attgctattt gtacaatctt atttgggtag
      721 caataccgct tggattggaa atagaagatt aataatagat gatgaatttg aaaaaatctt
      781 gctttcaaaa agttatgtaa aagaaatatc atctgcacga tactcagaat acttgacatg
      841 tgaatacaaa aaccttacac caatcatatt gatagctatt tttgaaaatt tgcttgactc
      901 ctacttgctt cagaatcaga gtgaggttga cttagatatt ttttataaag ttttaccttt
      961 gctttataaa gaaaaatata ctatgggatt caattacttt gtaagtttaa attatttact
     1021 atataaggtt ggatttttgg gaatcattta cgataatgaa gcattaagag atttgtcaaa
     1081 acaatattta aacaaaaata tttcggaatt acaagatggt tctttcgagg gcggtataca
     1141 agatgctgtt gcctctaaac aaatagtagt tataaatgaa tttatagctt gtttaaattc
     1201 caaatgcatg ccatcccaat atgatagatt tttttataaa gatagacctt atattttttc
     1261 cagaaagagt tctattaagg ggtgaaaatt tgttacattt ggattaacaa gtgtcctagg
     1321 gattagaaat aactctagta tagctagata tttttgagta actagaaata tcattaggct
     1381 actcatatga ttgccagaaa agatggctga tgaatcttat ttatactgtt gcagtaggcg
     1441 ttgtctagga taaataagct atcttgatgg gggagattgg aataatttta gtagaaacat
     1501 taaaggatta tgggcaagta gcacaggatt aggtgatgca atgtgctaag ttggcttggt
     1561 gttagcagta gtattattta acaatggaaa gtagactaaa tgaaaaataa acgttatttt
     1621 tttgacacaa ttttaatgat tttactactt ataagcacga tattttgtgt cagcccagta
     1681 tttataaaat tggacatctt aggaactccc tctcatgcca tcttaacctt tgtattggcg
     1741 ataccgttat tctatatttt gtctcaatgc ttacatactt tgctattact agtttcctca
     1801 atcttttgta aattaagacc aatttatttt cattttatat ttgtgatcat tataggagct
     1861 aggaaatact atcgaattct ttttcaccaa ctaatgggat ttagtccagg agtagcagtg
     1921 ttttataagg agagtcaaac aactaagaat ctgtttaaat tttactactt cttgtacttt
     1981 acaacactaa tttcacacta ttttttcttt acttttgtgt atgacaaacc gttgcttttg
     2041 cctcttattc cattttctat tatcatagca ttagtacaaa aactttatag aattgagaat
     2101 cagcaattat ttctgttaaa atcaaaggta ctaacaatac tggaatctaa gaagaattgt
     2161 gagtttaatc ttcaggatta tcatgaaatt tggaaattgc aatcaaaatc tgagttgcca
     2221 tgcgtggctt tatcttatat cagtttgatc aagccatatc tttcagagag tgtgcgtgaa
     2281 caaattgatt tattagaagt taagcgattt aaaaaaataa atcatccaat atcactttat
     2341 ggtatgttgg atgttataaa attaaatcta tatttacggc attataatga aaaaaataaa
     2401 tatgaatcaa tgttaaagaa aattttagag gtaagaccag actttgtttt aatcgagcag
     2461 aatattgatg atagtttaaa tagctcgcaa ccattatctt tatctttagc catttcagaa
     2521 atccaacttt tgcttgaagt gtatatgggg atcaaacatg tttcaattag gagataaaac
     2581 cagaataata tttgccatta taggggcaag ttgcatatta gtcagtatgt atcttattcc
     2641 acttattaaa actgagaata aattttggga aatactttta tttatattag gtgtattgct
     2701 aattggaatt gcgttattaa gtcaaaaaaa ataaattttg aaatagtatt agtgagttcg
     2761 caatcattta ttgctagtgg tttagaactg ttaagtttca aacaataatt gattttaaac
     2821 cttaggtaac ctataaaaac aaataaggta gagaaaggat atcttatcta ggtagctaag
     2881 tgataaaaac acagtcgtct atcacttgtt aggaaactat cctaactatg cttaataaaa
     2941 aaggagaaaa taaatggaac tcgtattacc aaataattat gttgttcttg agcaagaaga
     3001 gatgatgtat cttgatgggg gattttctat tccgagatgg cctgttgcaa cagccattaa
     3061 tatagctttt aatggtgttt taggtggagg agcaatcagt ctagttagaa attatattcg
     3121 taattatggt ttgcggcgag ttacaagcgc aattgctgga gcagctgcaa gatatgttgg
     3181 ggtacgagtt gcaaatagag tggcaggatt tgcactgtct gctattaatg gatttgcagc
     3241 ttggatgtca attggcaatg ctattacaac aatctgggcc aataatgatg taaataggag
     3301 agacccaaat ttaaacgcct tgtggtaact agatatgggt attaaaatgg aaaaaatttt
     3361 tgttattatt ttttttgtat gtctatttat atcatccata acttttttag cctatgattt
     3421 tgttagcgaa gaaataaaaa agttgattat ttggattaat gtcgtttttt tgattttaat
     3481 catagcaatg ataatttatc caaaattaag aaaatgataa ggacactgta aaattatgat
     3541 acgtaaacta atcatttttt tattaatgct ccctcttttt gtcttgtggc tagagttgca
     3601 tttgttagtg agtaacttgc aattgaatct agaaattccc tttgattttg tggttagtac
     3661 gagtcttact ttttttgttt tgatattatc aaaaatagtt ttagacatac tatacgcatt
     3721 gaaagatttg tacaagaaag aagctcttat tacgattttt ccttttattt ttataggcag
     3781 gaagaaagta aatgtgaggt tctcgcccta tttttcattc catcgtaaaa gtttgtcgcc
     3841 tgatgattta agatctagga ttatatggag ttttattctt gaaattgcta ttatcctagt
     3901 atttatttta aaaattcctt ttgcaatcat catgcttact acaatatttt tctggactat
     3961 aatggatatc aatcatctcg tttttaataa gacggaattt ctttttaatc aaaacaaatg
     4021 gcaaaaagaa gattcgtttg aaagtgattt gacgaaaacg ttaaaggata agatacaaaa
     4081 atcagaatta agctattctg acttaatgtc ccttcttctc tatgatgcga tgaaccaatc
     4141 caccttttta acggatagtg aactttttga ggatattttg aaaaaaatcg aagattctca
     4201 taacaccctt ctgtgtacag gtcttgtcga gttactgctg tatgaaattt ctattagtaa
     4261 gaatcataat tggtcagaaa agattgataa aattaggata gagcttatca agattaatca
     4321 attagatttt ttctattata caagttggtt aaggcaaaat tttgatttct gtatgaatag
     4381 agagtatcat aaaatgaaat ctcggaaatt attactgagt aataaaaaga tagtttaagt
     4441 tcgtcctatt tgtaaaacaa atgaaacaat ttcaactaag gaggagaaaa caaatggaac
     4501 ttgtattacc aaataattat gttgtgattg atgaagaagt aatgatgtat cttgatgggg
     4561 gagcttattt aagcaagcgt gcttgtcaag gaatttgcgc agctttagct atgagttcag
     4621 gaacttttat agcattagct ggagctgcag ttttaaccaa aaaactaata aactatatta
     4681 agtttggagg tcttggaggc tggcttattg gtgcagcagc aggtgtattg gctacagcag
     4741 caggaaaaat agcttactgt attggatatg gtgttcttaa tagaggttgt gatattaatg
     4801 ggaaccctta tccttgggat ggattcatat ctgcaacagt aagatgagta atgtagataa
     4861 gattcgaaaa atacacatca tcgtgtgttg ggtgtatata tttttatcat tcagggcgat
     4921 tataaatgat acggagtatt ttttgcttat ttttttagct tttatctact caatagtatc
     4981 actacctcta tattctgtga aaaataaaat agtatctatc tgtctagcca taaattcgat
     5041 tctgttaatc agtttcccca ttttaatcaa taagtttttc ccagaaagtt ttttgactta
     5101 taccgtatta ataagtgttt ttattacaga gttgataatt tttcatttaa ttgggaaaga
     5161 ttttgatact aaattgacta acgaatataa gaaaattagt cagtttagaa gcaaggtgtc
     5221 tcaatctcct tggataaaat atttagagat ttctagtttt atattaacta tatttccatc
     5281 tattctttat ggtacagttg ataatcatgt actgactctt atctttttga taaaaatttg
     5341 tgtagatact acgataaaat ttttattcat cagattattt gacacaagta ctttaatgaa
     5401 gaggagaata ttttttcttt tcgcattgga tgttatagct tacttatttt taggatatct
     5461 tttagtgatt caaaaagcag gatatctgtt ttcgatttta cttcttttct ctaatttttc
     5521 agttccattt atcaaagaaa aggaatacga attatttaaa aatagcaagt aatagaaaca
     5581 taggttaaat cttagaacgg cttaaaatca gatatgataa agggaaatag tcttatctag
     5641 gtaactaagt gctacaaaca caatcgagga tcacttgtta ggattacatt ttaatcatgc
     5701 ttaataagaa tggagaattc ctatggggat tgtattactc tgaagtttcg aataccttag
     5761 ttctcgtgat tttgagctat tctaggttta gaatccttca gaatgtaaaa ttttaagcag
     5821 tcaaagactt agaatagcct gaaaacattt attttataac aattctaggc ttagaattgc
     5881 tcatatatat gtacttgagc tgctcgatag ttaggacagc tctattctga gaaatctgag
     5941 ctatcaatgc ttcagaatag tatttcgcca atggttttta ttgaagaggt gattgtgtta
     6001 tgatagtcta aaataaaatt gatttaatag agtaaatgga gaatcgttac atgaaacatt
     6061 tttttgcagg aattggtgag ataaaacttg ttggctactt attgtatata tgtgtaggac
     6121 tagcccctct ttttcatata tatgtcatag gttcggaact gagttttgtg aaaatagtgt
     6181 tatctatttt gggagttata tttgtaagta tgttaactat tgctcgaatt tatcggactt
     6241 ttctataaag aatagtttgg acttgaactg tatctaaaaa cagaggttgg tagattatca
     6301 gcctctttct tgtcgttgaa aaaagtgaga tatattgact tttgaaaaaa atgtcataat
     6361 tgagttggga taaacgtaaa agtcatactt tctcgttaaa tcgttcggcg attctatgaa
     6421 aaggtcgagg agctccctcg acttttttta taatttcttt ggttgataat gggtctctac
     6481 ttcttttttg agatgagaca gcatagaagt ttcctcggtc agatccagaa gggagaaccc
     6541 tttttggata agtttagaat cgtctgtaca aatcccaatg cggacatagc agatagccag
     6601 cctatcgtag cttttcttat tcttggcgtc ctccagtaaa gtgtagcaga tttgcttaca
     6661 catgttttta tcttgattgt atagatagag tgtggaaagg tttagcagga ttgctattcg
     6721 caagtcatat aaatgttgat agtttttata gacttctagg cgttgcaata tttttccagt
     6781 gatgagatgg aggtattcaa tgggaaaact gaaaagaatg gtattgagga tttttagatc
     6841 actctcatac catgtatctt gtttttcaat ttttctccaa agttttttga caacctgttc
     6901 tgcgtgatct gatagttccc ctgccccgtg ttgacggaga taaatgacaa cttcaagcat
     6961 atctctgatt tcttctatag ggagatcgtg gtgggtcttg aggtagtctt ggcatttttg
     7021 aaataaattg acaagatcgc tggtcccgat aatggaacgc atattgagat aggtttgcat
     7081 aatctctgtg cgttgacttg gttgataaag ttgacagata tattcaaact cttcaaaact
     7141 catattgatt tgacggagaa gaaattccat attttcatat tttggggttg tcttgccact
     7201 ttcgattttt gataagctgg ttcttgagag aacaccccca cagacctctt cttgggtcag
     7261 cccctttgac tcacgtattt ctttatagac ctttccgaaa tcataacgca tgattttctc
     7321 ctttctgtga aaaaagttaa caaataataa aatcttgtta aaaatattgt atcatagcag
     7381 tgtaaaaagt aaaaaagaaa gtaaaaataa atttgtgaaa aaagttaacg taattttaaa
     7441 atgagcttaa taagaggtat gatgtaggta gaaaataaag ataggagaaa aagtatgaat
     7501 aaaaaaatat tttgtattct agtatgtatg atatcattga ttagtctggc cataatcttt
     7561 ccatggggct ggtcgatata atgtaaggga gcttgagttg ttaaaggagg cttagtcctt
     7621 ggacaaaaat ctgctgtact acaatgcttg gaaagatatc aagaacaaag aatgatacga
     7681 ttgaaaataa actgattcaa gaactactgg gcagtgattg aggtttgggt gacatcaaag
     7741 aaaagttaga ttaattctaa agaattgagt atttctatgt taaaaaaata tccttgtacg
     7801 atgcaacatg atcagtcaga ttgtgctgcg gcagttgttt caacagttct tttatcttac
     7861 aaaaaggaac tatcaatcat gaagattcgg gaaattattg gtacagacat gtatggaacg
     7921 actgtcagtg gtattgtttc aggtctgaat aagttgaatt ttacagtaaa agctgttcga
     7981 gtggcactgg aagatttgac tccaaaatta acatttcctg cgattcttca agttaagaat
     8041 gatttaggtc aaaatcattt tgtggtatta catagtataa aggagaaaat aaatggaact
     8101 cgtattacca aataattatg ttgctcttga gcaagaggag atgatgtatc ttgatggggg
     8161 ggcttattta agcaagagtg cttgtcaagg aatttgcgca gctttagcta tgagcccagg
     8221 aacttttata gcattgactg gagctgcagt tttaacaaaa aaactaataa actatattaa
     8281 ggttggaggc cttggaggtt ggcttattgg tgcagcagca ggtgtattgg ctcttatctt
     8341 tttgataaaa atttgtgtag atactacgat aaaggttcta ttaaacagaa tctttaaggc
     8401 aagtaaggta atgaaaagga ggatattttc tctttttgta ctagatttga tggtctatat
     8461 atttttaggt tatgttttag tgatacaaaa agacgtatat ctgttttcaa ttctgataat
     8521 tttttctaat ttttcagttc cctttatcag agaaaaagag tatgaattat ttaaaaataa
     8581 gaaatgagat agatatggta gctttattaa aactgagaat aaagtttggg agatattttt
     8641 atttatttta ggtgtgttgt taattgtaat ttcattacta agtcccccaa aaattaaatt
     8701 ttggaaatag agttagtgag aaggatagga taatagtatt atgttgattg ttttaatttc
     8761 agttattgtt gcattactgt atcataaaat tacagagtat gtcaacaaca ggaaaattga
     8821 tattgttatt tttctatcat tgctgatttc tcattttatt tggaattact attttttacc
     8881 aattgaaata ttgatagcaa tcagtggagc aaatttacta tt
//
LOCUS       DBEJAU010000070         8648 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC323 isolate 683620
            SAMN38261939-rid24807223.denovo.070, whole genome shotgun sequence.
ACCESSION   DBEJAU010000070 DBEJAU010000000
VERSION     DBEJAU010000070.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261939
            Sequence Read Archive: SRR26833919
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 8648)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8648)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576303.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576303.1
            Genome Coverage       :: 154x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/19/2025 01:05:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,121
            CDSs (total)                      :: 2,078
            Genes (coding)                    :: 1,943
            CDSs (with protein)               :: 1,943
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 36
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 72 of 135
            Pseudo Genes (incomplete)         :: 63 of 135
            Pseudo Genes (internal stop)      :: 51 of 135
            Pseudo Genes (multiple problems)  :: 46 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8648
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261939-rid24807223.denovo.070"
                     /strain="GPSC323"
                     /isolate="683620"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            <1..555
                     /locus_tag="ACL29Z_001921"
     CDS             <1..555
                     /locus_tag="ACL29Z_001921"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000945326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate uptake regulator PhoU"
                     /protein_id="HGR0070176.1"
                     /translation="KLFEYLSNEERVELIKEDLIINESVLNIDKKGYELICLQHPVSY
                     DLRRIISVIKISTDIERIGDRIVEILKNLQILQNNEILKKIISKIKILHEVIGLHMNR
                     AISCYREEQSGCLDMVVIQKQNEIEELSINMEKKIMNYIFEDDGNVSEVISALDIIHH
                     LDKIAHTTQAIYKWIMYRKYGNIN"
     gene            568..2043
                     /gene="galT"
                     /locus_tag="ACL29Z_001922"
     CDS             568..2043
                     /gene="galT"
                     /locus_tag="ACL29Z_001922"
                     /EC_number="2.7.7.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000848801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0017103 - UTP:galactose-1-phosphate
                     uridylyltransferase activity [Evidence IEA];
                     GO_process: GO:0019388 - galactose catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose--hexose-1-phosphate
                     uridylyltransferase"
                     /protein_id="HGR0070177.1"
                     /translation="MKTIIDNFVDRVIEYGMYNEIDKIYVKNRVLALIGEEGIDRISD
                     ENDLKQIKDYLVEIALKNGKIKDLIEEKECLGAELMNFIVPLPSRLNDIFWSSYDISP
                     QEAVEEFYKLSKDSDYIKTSAIAKNIEFRASTKYGELEITINLSKPEKDPKTIAAEKL
                     VKATNYPKCLLCMENEGYQGRINYPARSNHRIIRLKLGDEVWGFQYSPYSYFNEHAIF
                     LNSQHVPMAITSKTFEQLLEIVDILPGYFAGSNSDLPISGGSILSHNHYQGGKHIFPM
                     EKAKFESEFCFKDFEDVNAGIVKWPMSVIRLQSENKNRLLDLATKILNKWREYSDLEV
                     DIIAMTEDVPHHTVTPIARKVDGRYELDIVLRDNHTTEQYPDGVFHPHQDVQHIKKEN
                     IGLIEVMGLAILPPRLKPELEEVGKYLLGEDNAIADYHLEWADQLKEKYPRINKEEVN
                     SVVQHEAGQVFARVLEDAGVYKNTPSGHEAFMRFVKSVGIN"
     gene            2056..3066
                     /gene="galE"
                     /locus_tag="ACL29Z_001923"
     CDS             2056..3066
                     /gene="galE"
                     /locus_tag="ACL29Z_001923"
                     /EC_number="5.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000996568.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003978 - UDP-glucose 4-epimerase activity
                     [Evidence IEA];
                     GO_process: GO:0006012 - galactose metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose 4-epimerase GalE"
                     /protein_id="HGR0070178.1"
                     /translation="MAILVTGGAGYIGSHTVVELLNLGKEVIIVDNLSNSSKLVLDRI
                     EAITGIRPVFYELDVCDKQALRKVFEQESIDAAIHFAGYKAVGESVQKPVMYYKNNIM
                     STLALVEVMSEFNVKKIVFSSSATVYGINNQSPLIETMQTSATNPYGYTKVMLEQILK
                     DVHVADSEWSIALLRYFNPIGAHESGLIGEDPSGIPNNLMPYIAQVAVGKLSELSVFG
                     NDYDTLDGTGVRDYIHVVDLAIGHIKALEKVSEKTDVYIYNLGSGEGTSVLQLVNTFE
                     SVNKIPIPYKIVPRRSGDVATCYANADKAYKELNWRTTKSIEDMCRDTWNWQSKNPNG
                     YN"
     gene            3246..3905
                     /locus_tag="ACL29Z_001924"
     CDS             3246..3905
                     /locus_tag="ACL29Z_001924"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000793810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1868 domain-containing protein"
                     /protein_id="HGR0070179.1"
                     /translation="MKNLTKIKFKENGEFNHFPGNTVVANLYTKQDLMEVVDIIQSRY
                     RELPFIDKFTLTPRNSIHMTVIELLCHENRETEFWSSNLPLDTPLQEIHDYFAKQLEI
                     FPLLDEEIHMRITEMGKQNILVEPADEASAKRLEEIRTYVSEKAGVCFPNHDRYQFHI
                     SIGYLRIPLTEEEEEEFTKVRAELTEILLEKIPTITVNRIDYTVFEDMRQFVPYHEKF
                     K"
     gene            3930..4997
                     /locus_tag="ACL29Z_001925"
     CDS             3930..4997
                     /locus_tag="ACL29Z_001925"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000738359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HGR0070180.1"
                     /translation="MKKMKVWSTVLATGVALTTLAACSGGSNSTTASSSEEKADKSQE
                     LVIYSNSVSNGRGDWLTAKAKEAGFNIKMVDIAGAQLADRVIAEKNNAVADMVFGIGA
                     VDSNKIRDQKLLVQYKPKWLDKIDQSLSDKDNYYNPVIVQPLVLIGAPDVKEMPKDWT
                     ELGSKYKGKYSIYGLQGGTGRAILASILVRYLDEKGDLGVSEKGWEVAKEYFANAYTL
                     QKGESSVVKALDKESPIQYGMIWGSGALIGQKEQNVEFKVMTPEIGVPFVTEQTMVLS
                     TSKKQALAKEFIDWFGQSEIQVEYSKKFGSIPANKDALKELPEDTKKFVDQVKPQNID
                     WEAVGKHLDEWVEKAELEYVK"
     gene            5101..6111
                     /locus_tag="ACL29Z_001926"
     CDS             5101..6111
                     /locus_tag="ACL29Z_001926"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001847714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGR0070181.1"
                     /translation="MIKFDNIQIKYGDFVAIDNLNLDIHEGEFFTFLGPSGCGKSTTL
                     RALVGFLDPSSGSIEVNGTDVTHLEPEKRGIGIVFQSYALFPTMTVFDNIAFGLKVKK
                     VAPDVIKAKVSAVAAKIKISDQQLQRNVSELSGGQQQRVALARALVLEPKILCLDEPL
                     SNLDAKLRVDLRKELKRLQKELGITTLYVTHDQEEALTLSDRIAVFNNGYIEQVGTPV
                     EIYHNSQTEFVCDFIGDINVLTDEIVREVLLKNTSVFLEDKKGYIRLEKVRFNRETEQ
                     DFILKGTIIDVEFSGVTIHYTIKVSESQILNVTSIDSQAAIRSVGESVELFITPSDVL
                     QF"
     gene            6123..7814
                     /locus_tag="ACL29Z_001927"
     CDS             6123..7814
                     /locus_tag="ACL29Z_001927"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861837.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0006826 - iron ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HGR0070182.1"
                     /translation="MRHKLNLKDWLIRLGLIWFLVTFIIYPNFDLVVNVFVKGGEFSL
                     DAVHRVLKSQRALQSIMNSFKLAFSLIITVNVVGILCVLFTEYFDIKGAKILKLGYMT
                     SLIYGGVVLATGYKFVYGPYGLITKFLQNVIPSLDSNWFIGYGAVLFIMTFSGTANHT
                     LFLTNTIRSVDYHTIEAARNMGAKPFTVFRKVVLPTLIPTLFALTIMVFLSGLSAVAA
                     PMIVGGKEFQTINPMIITFAGMGNSRDLAALLAIILGIATTILLTIMNKIEKGGNYIS
                     ISKTKAPLKKQKIASKPWNIIAHIVAYGLFTVFMLPLIFIVLYSFTDPVAIQTGNLTL
                     SNFTLENYRLFFSNSAAFSPFLVSFIYSIIAATTATILAVVFARVVRKHKSRFDFLFE
                     YGALLPWLLPSTLLAVSLLFTFNQPQFLVLNQILVGSLVILLIAYIVVKIPFSYRMVR
                     AILFSVDDEMEDAARSMGASPFYTMMKVIIPFILPVVLSVIALNFNSLLTDFDLSVFL
                     YHPLAQPLGITIRSAGDETATSNAQALVFVYTIVLMIISGTVLYFTQRPGRKVRK"
     gene            7817..8527
                     /locus_tag="ACL29Z_001928"
     CDS             7817..8527
                     /locus_tag="ACL29Z_001928"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000127555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MgtC/SapB family protein"
                     /protein_id="HGR0070183.1"
                     /translation="MTATSLGLSNIEIVVRIVLSVVIGSIIGLERGSKSQPAGIRTYS
                     IVCLAACLIMMTNEYVSYKFGTGDPTRLGAQVISGVGFLGAGTILITDKKKITGLTTA
                     AGIWASAGIGLAIGVGFYEGALLVAISVWGVISMFQPLKKYLQNRSKMIELYIVVKST
                     EAYNRVLVYCAENGIRMTDSRTAFGDVNSDRIEYFDVPDKKIASFITLELSGRFEHLR
                     LMEEIANIVGVIYVEEIS"
BASE COUNT         2963 a         1172 c         1691 g         2822 t
ORIGIN      
        1 aagttatttg aatatttatc aaatgaagaa cgagtagaat tgattaaaga agatttaatc
       61 ataaatgagt cagttctaaa tattgataaa aaaggatatg agttaatttg tttacaacat
      121 cctgtttcat atgacttaag aagaattatt agtgtaataa aaatatcaac tgacattgaa
      181 cgtattgggg atagaattgt tgaaatttta aaaaatctac agattcttca aaataatgaa
      241 attttgaaga aaattatttc aaaaataaaa atacttcatg aagttatcgg actgcatatg
      301 aatagggcta tatcttgtta tagagaggaa caatctggat gtttagatat ggttgttata
      361 caaaaacaga atgagataga agagcttagt ataaatatgg aaaagaaaat aatgaattac
      421 atatttgaag atgatgggaa cgtttctgaa gtaattagtg ctttagatat tattcatcac
      481 cttgataaaa ttgctcatac tacgcaagca atttataaat ggataatgta tagaaaatat
      541 gggaacataa attagaaaga aaaatatatg aaaacaatta ttgataattt tgttgataga
      601 gtaattgaat acggaatgta taatgaaatt gacaaaatat atgtgaaaaa tagagtacta
      661 gcgttaatag gtgaggaggg aattgatcgc atttccgatg aaaatgacct gaaacaaata
      721 aaagattact tagtggaaat cgccttaaaa aacggtaaaa ttaaagattt aatcgaggaa
      781 aaggaatgtt taggagcaga gttaatgaat ttcatagttc ctttacctag tcgattaaat
      841 gatatttttt ggagttcata tgatatatca cctcaagaag cagttgaaga gttttataag
      901 ttaagtaaag atagtgatta tattaaaact tctgctattg ctaagaatat tgagtttcga
      961 gcatcaacta aatacggaga gctagagatt acgataaatt tgtcaaaacc cgaaaaagat
     1021 ccaaaaacaa ttgctgctga aaaattagta aaagcaacta attatcccaa atgtttacta
     1081 tgtatggaaa atgaaggata tcaggggcga ataaattatc cagcacgttc gaatcataga
     1141 attattcggt tgaaacttgg tgacgaagta tggggattcc agtattctcc ctactcatac
     1201 tttaatgagc atgcgatatt tttgaatagt caacatgtac caatggctat tacctctaaa
     1261 acatttgaac aattattgga gattgttgat attttgccag gatattttgc tggttcaaat
     1321 tctgatcttc ctatctcagg aggctccatt cttagtcata accactacca gggagggaaa
     1381 catattttcc caatggaaaa agcaaaattt gagagtgaat tttgttttaa agactttgag
     1441 gatgttaatg ctggtattgt aaaatggcca atgtcagtaa ttaggttaca aagtgaaaat
     1501 aaaaatcgct tgttagattt agctactaaa attctaaata agtggagaga atattcagat
     1561 ttagaagtag acatcattgc tatgactgaa gatgtcccac accatacggt gactcctatt
     1621 gctcgtaaag tggacgggag atacgaatta gatattgttc taagagataa tcatactact
     1681 gaacaatacc cagatggtgt tttccatcct catcaagatg tacaacatat taaaaaggaa
     1741 aatatcgggt taatcgaagt gatgggactt gcgatattac cacctcgttt gaaaccagag
     1801 ttagaagaag ttggaaaata tcttttagga gaggataatg caattgcgga ttatcattta
     1861 gaatgggccg accaattgaa agaaaaatat cctcgcatta ataaagaaga ggttaatagc
     1921 gtagttcaac acgaagcagg acaagtgttt gcgagagttc tggaagatgc aggagtttat
     1981 aagaatacac cgtctgggca tgaagcgttt atgagatttg ttaagtcggt tggaattaat
     2041 taggaggaaa cccagatggc aatattggta acaggcggag ctggttatat tggtagccat
     2101 accgtagtag aattactaaa tttaggaaag gaagttatca ttgtcgacaa cctttcgaac
     2161 tctagcaaat tggtgctaga ccgtattgaa gcaattacag gaatacgtcc cgtgttttac
     2221 gaattagatg tttgtgataa acaagcattg agaaaggtat ttgaacaaga atcgattgat
     2281 gctgcaattc attttgcagg ttataaagct gtcggagaat ccgtgcaaaa gcctgtgatg
     2341 tactacaaaa ataatattat gagtacattg gcacttgttg aagtgatgtc agaatttaat
     2401 gttaaaaaga ttgtcttttc ttcaagtgcg actgtatatg gaattaacaa tcagtcacct
     2461 ctaattgaga cgatgcaaac aagtgcgaca aatccttatg ggtatacgaa agtgatgctt
     2521 gagcaaattt taaaagatgt tcatgtggca gattcagaat ggagtattgc gttgcttcgt
     2581 tatttcaatc caattggtgc tcatgagtct ggtttgattg gggaagatcc ctcaggaatt
     2641 cctaacaact tgatgcctta tattgcacaa gtagcggtag gtaagctatc agagctaagt
     2701 gtgttcggaa atgattatga tacgcttgat ggtactggtg tgcgtgatta tatccatgta
     2761 gtagatttag caataggaca tataaaagct ttagaaaaag tatctgaaaa aacagatgtt
     2821 tatatctata acctaggctc gggagaaggc actagtgtat tacaacttgt aaatacattt
     2881 gaaagtgtta ataagatccc tattccttat aaaatagttc caagacgttc aggagacgtt
     2941 gcaacttgtt atgcaaatgc agacaaagca tataaggaat taaattggag gacaacaaaa
     3001 tcgattgaag acatgtgtag agatacatgg aattggcaat caaaaaatcc caatggctat
     3061 aattgatgat actgtctata tgagtgctgt attttgaaaa aattacttaa ccttttaatg
     3121 aaatgcatat ttaatgaaag ataaatttaa aaaaatgttt gcaagtgctt gacaaaggaa
     3181 acggtttcat tgtataatgt aaacatgatg acaccgatgt caaatataaa aaagaaggtc
     3241 tttatatgaa aaacttaaca aaaattaagt tcaaagagaa tggggaattt aatcatttcc
     3301 ctgggaatac agttgtagca aatctttata ctaaacaaga tttgatggaa gttgttgata
     3361 ttattcaatc acgttataga gaattaccat ttatcgataa gtttacttta actccaagga
     3421 attctattca catgactgta attgaattgt tgtgccatga aaatcgtgaa acggagtttt
     3481 ggagcagtaa tcttcctcta gatacacctt tacaggaaat acatgattac tttgctaaac
     3541 aacttgaaat ttttccattg ttggatgaag aaattcatat gcgtataact gaaatgggaa
     3601 aacaaaacat actagttgaa cctgcagatg aagcttctgc aaagagatta gaagaaattc
     3661 gtacttatgt ctcagaaaaa gcaggtgttt gtttccctaa tcatgataga tatcaattcc
     3721 atatttcaat tgggtatctt cggattcctc taaccgaaga ggaggaagaa gagtttacta
     3781 aagtcagagc agaattaact gaaattttat tagagaagat tccaactatt actgtaaacc
     3841 gtattgacta tactgtattt gaagatatga gacaatttgt tccatatcac gaaaaattta
     3901 aataaaataa taaaaaagga gaacttatca tgaaaaaaat gaaagtttgg tctactgtac
     3961 ttgcaacggg agttgctctt actacacttg ctgcttgctc tggaggttca aattctacga
     4021 ctgcttcttc atctgaagaa aaagctgata aaagtcaaga attagttatc tattcgaact
     4081 cagtctcaaa tggtcgtggt gattggttaa ctgctaaagc aaaagaagct ggttttaata
     4141 taaaaatggt tgatatcgct ggcgctcaat tagcagaccg tgttattgct gagaagaata
     4201 atgcagttgc agatatggta tttggaattg gtgctgttga ctcaaataaa attagagatc
     4261 aaaaattact agtacagtac aagcctaaat ggttagataa aattgatcaa tctttatcag
     4321 ataaagataa ttattataat cctgtgattg ttcaaccatt agttttaatt ggggcgcctg
     4381 atgtaaaaga aatgcctaaa gattggactg aattaggtag taagtataaa ggtaaatatt
     4441 caatttatgg tcttcaaggt ggtacaggac gggcaattct agcaagtatc ttagttcgtt
     4501 accttgatga aaaaggagat ttaggcgtat cagaaaaagg atgggaagtt gcaaaagaat
     4561 actttgcaaa tgcctatact cttcaaaaag gtgaaagctc agttgttaaa gcgttagata
     4621 aagaaagccc aattcaatac ggtatgatct ggggttctgg agcgttaatt ggacaaaaag
     4681 aacaaaatgt tgaattcaaa gttatgactc ctgagattgg tgtaccattt gtaactgaac
     4741 aaactatggt tttaagcact agtaaaaaac aagcgttagc taaagaattt attgattggt
     4801 ttggtcaatc agaaattcaa gtagaatata gtaaaaaatt tggatctatt cctgcaaata
     4861 aagatgccct aaaagagtta cctgaagata cgaaaaaatt tgttgatcaa gtgaaaccac
     4921 aaaatattga ctgggaagct gttggaaagc atttggatga atgggtagaa aaagctgaat
     4981 tagaatacgt aaaataagaa ataagagtta ttttttatgt ccaagtctct ctattatttc
     5041 taaatttaag gaagaaataa agagaggctt ttggttttag taatagaggg agttagtgag
     5101 atgattaaat ttgataatat tcaaattaaa tatggtgatt ttgttgcaat tgataatctg
     5161 aatttagata tacatgaagg ggaattcttt acatttcttg ggccttcagg atgtggtaaa
     5221 tcaactactt tgagagcatt ggtaggtttt ttagatccat catcaggaag tattgaagtt
     5281 aatggaacag atgtcactca tttggaacct gaaaagcgtg gaattggtat tgtatttcaa
     5341 tcttatgcgc tatttccaac tatgactgtt tttgataata ttgcatttgg tttaaaagtt
     5401 aagaaggtag ctccagatgt tattaaagct aaagtatcag cagtggcagc aaaaattaag
     5461 atctctgatc aacagttaca gcgtaatgta tcagaattat ctgggggtca acaacaaagg
     5521 gtagcattgg ctcgtgctct ggttcttgaa cctaaaattc tttgtctaga tgaaccattg
     5581 tcaaaccttg acgcaaaatt acgtgtagat ttgagaaaag agttgaaaag acttcaaaaa
     5641 gagttaggta ttactacttt atatgttact catgatcaag aggaagcctt gactttatct
     5701 gatagaattg cagtctttaa caatggatac atcgaacagg tcggtacacc agtagagatt
     5761 tatcataatt ctcaaactga atttgtatgt gattttattg gagatattaa tgttttgacc
     5821 gatgaaatag tccgcgaagt attattgaaa aatacaagcg ttttcttaga ggataaaaaa
     5881 ggatacattc gattagagaa agttcgattc aatcgtgaaa ctgaacaaga ttttattcta
     5941 aaagggacaa ttattgatgt tgagttttct ggagttacaa ttcactatac aataaaagtt
     6001 tctgaaagtc agattcttaa tgtaacaagt attgatagtc aggctgctat tagatctgtc
     6061 ggagaaagtg tggaattatt tatcacacca tcagacgttc tgcaatttta aggaggtgca
     6121 gtatgcgtca taaattaaat ttaaaagatt ggcttattcg tttagggtta atctggttct
     6181 tagtaacatt tattatttat ccaaactttg atctagtagt gaatgtattt gtaaaaggag
     6241 gagaattttc ccttgatgct gtacatcgtg ttctaaaatc tcagagggca cttcagagta
     6301 ttatgaacag ttttaagtta gcattttcac tcattattac agttaatgtc gtaggtattc
     6361 tttgtgttct atttacagag tactttgata ttaaaggtgc taaaatttta aaattaggtt
     6421 atatgacctc tttaatttat ggaggagtgg ttttagcgac tggatataaa tttgtctatg
     6481 gtccttatgg attgattaca aaatttttac aaaatgttat cccttcttta gactctaact
     6541 ggtttattgg gtatggtgca gtcttattca ttatgacatt ttcaggaact gctaatcata
     6601 cattgttttt aacaaataca attcgaagcg ttgactatca cactattgag gctgctcgaa
     6661 atatgggagc aaaaccattt actgttttcc gaaaagtagt gttaccaacc ttaattccaa
     6721 ctctatttgc acttactatt atggtttttc ttagtggttt atctgcagta gcagcaccca
     6781 tgattgttgg tggtaaagaa tttcaaacta taaatccaat gattattaca tttgcaggga
     6841 tggggaattc tcgtgattta gctgccctac ttgcaattat tttaggtatt gcaactacaa
     6901 ttttgcttac tatcatgaat aagatagaaa aaggtggaaa ttatatttct atctctaaga
     6961 ctaaagcgcc tcttaaaaaa caaaaaattg cgtctaagcc ttggaatatc attgctcaca
     7021 ttgtagcata tggattgttc acagttttca tgcttccact aatttttata gtattatact
     7081 catttacaga tccagttgca attcaaacag gtaacttaac attatcaaac tttactttag
     7141 aaaattatcg cttattcttt agtaatagtg cggcattctc tccattcttg gtcagcttta
     7201 tttattctat tattgctgcg acaacagcaa caattctcgc agttgtattt gctcgtgttg
     7261 tcagaaaaca taaatctcgt tttgatttct tatttgaata tggtgcacta cttccttggt
     7321 tactaccaag tacactttta gcagtaagtt tattatttac ttttaatcag ccacaatttc
     7381 ttgtcttgaa tcagattttg gtaggtagtt tggtaattct acttattgca tatatagttg
     7441 taaaaatccc attttcttat agaatggtac gtgctatttt atttagtgtt gatgatgaga
     7501 tggaagatgc agcaagaagt atgggtgctt caccttttta tactatgatg aaggttatca
     7561 ttccatttat tttaccggtt gttctctctg ttattgcttt aaactttaac tctttattaa
     7621 ctgacttcga cttatctgta ttcctttacc atcccctagc tcaaccatta ggtattacaa
     7681 ttcgatctgc aggtgatgaa acagcaacat ctaatgcaca agctctggta tttgtttata
     7741 caattgttct gatgattatt tctggaacgg tattatactt cacacaaaga ccggggcgta
     7801 aagtaaggaa ataatcatga cagccactag tcttgggtta tcaaatattg aaatagttgt
     7861 caggattgtt ttatcagtag tcattggtag tataattggt ttagagagag ggagcaaatc
     7921 ccagcctgca ggcatccgaa cttatagtat tgtttgtcta gctgcatgtt tgattatgat
     7981 gacgaatgaa tacgtatctt ataaatttgg gacaggagat cctacacgat taggagctca
     8041 agttatatca ggtgtgggtt ttctaggcgc tggaacgatt cttattacag ataaaaagaa
     8101 aattacaggt ctgacaactg cagcaggcat ttgggcttcg gcaggaattg gattagctat
     8161 tggagtaggt ttttatgagg gagctctttt agtagccatt tctgtttggg gtgtgatatc
     8221 catgttccaa ccactaaaaa aatatctgca aaatcgttct aaaatgattg aattgtatat
     8281 agtagttaaa tctacagaag cctataatcg tgtattggtt tattgtgcag aaaatggtat
     8341 cagaatgacc gattcaagaa cagcgtttgg agatgttaat tctgacagaa ttgaatactt
     8401 tgatgttccg gacaaaaaaa tagcgtcatt tattactctg gaattatcag gtagatttga
     8461 acatcttcga ctgatggaag aaattgctaa tattgtaggt gttatttatg tcgaagaaat
     8521 tagctgaaat ttagtaaaca aagggacaga tgtttttgtc cttttgtttt ttagatgttt
     8581 taatcatcta atttttgagt agatttttgc tcagaggttt ttatgaaaga ttataaaatc
     8641 aattttga
//
LOCUS       DBEJAU010000071         7848 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC323 isolate 683620
            SAMN38261939-rid24807223.denovo.071, whole genome shotgun sequence.
ACCESSION   DBEJAU010000071 DBEJAU010000000
VERSION     DBEJAU010000071.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261939
            Sequence Read Archive: SRR26833919
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 7848)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7848)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576303.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576303.1
            Genome Coverage       :: 154x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/19/2025 01:05:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,121
            CDSs (total)                      :: 2,078
            Genes (coding)                    :: 1,943
            CDSs (with protein)               :: 1,943
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 36
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 72 of 135
            Pseudo Genes (incomplete)         :: 63 of 135
            Pseudo Genes (internal stop)      :: 51 of 135
            Pseudo Genes (multiple problems)  :: 46 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7848
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261939-rid24807223.denovo.071"
                     /strain="GPSC323"
                     /isolate="683620"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            complement(1..981)
                     /gene="dusB"
                     /locus_tag="ACL29Z_001929"
     CDS             complement(1..981)
                     /gene="dusB"
                     /locus_tag="ACL29Z_001929"
                     /EC_number="1.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0017150 - tRNA dihydrouridine synthase
                     activity [Evidence IEA];
                     GO_function: GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA];
                     GO_process: GO:0008033 - tRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA dihydrouridine synthase DusB"
                     /protein_id="HGR0070184.1"
                     /translation="MTNLNTPFMIGNVEIPNRTVLAPMAGVTNSAFRTIAKELGAGLV
                     VMEMVSDKGIQYNNEKTLHMLHIDEGENPVSIQLFGSDEDSLARAAEFIQENTKTDIV
                     DINMGCPVNKIVKNEAGAMWLKDPDKIYSIINKVQSVLDIPLTVKMRTGWADPSLAVE
                     NALAAEAAGVSALAMHGRTREQMYTGHADLETLYKVAQALTKIPFIANGDIRTVQEAK
                     QRIEEVGADAVMIGRAAMGNPYLFNQVNHYFETGEILPDLTFEDKMKIAYEHLKRLIN
                     LKGENVAVREFRGLAPHYLRGTSGAAKLRGAISQASTLAEIEALLQLEKA"
     gene            complement(968..1840)
                     /gene="hslO"
                     /locus_tag="ACL29Z_001930"
     CDS             complement(968..1840)
                     /gene="hslO"
                     /locus_tag="ACL29Z_001930"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000357853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0051082 - unfolded protein binding
                     [Evidence IEA];
                     GO_process: GO:0006457 - protein folding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Hsp33 family molecular chaperone HslO"
                     /protein_id="HGR0070185.1"
                     /translation="MDKIIKTISESGAFRAFVLDSTETVRTAQEKHQTQASSTVALGR
                     TLIASQILAANEKGNTKLTVKVLGSSSLGAIITVADTKGNVKGYVQNPGVDIKKTATG
                     EVLVGPFVGNGQFLVITDYGTGNPYNSITPLISGEIGEDLAFYLTESQQTPSAVGLNV
                     LLDEEDKVKIAGGFLVQVLPGAKKEEIARFEKRIQEMPAISTLLESDDHIEALLKAIY
                     GDEAYKRLSEEEIRFQCDCSHERFMNALASLPSSDLQEMKEEDHGVEITCQFCQTTYN
                     FDEKDLEELIRDKS"
     gene            2005..3432
                     /locus_tag="ACL29Z_001931"
     CDS             2005..3432
                     /locus_tag="ACL29Z_001931"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000280545.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HGR0070186.1"
                     /translation="MYLGDLMEKAECGQFSILSFLLQESQTTVKAVMEETGFSKATLT
                     KYVTLLNDKALDSGLELAIHSEDENLRLSIGAATKGRDIRSLFLESAVKYQILVYLLY
                     HQQFLAHQLAQELVISEATLGRHLAGLNQILSEFDLSIQNGRWRGPEHQIRYFYFCLF
                     RKVWSSQEWEGHMQKPERKQEIANLEEICGASLSVGQKLDLVLWAHISQQRLRVNACQ
                     FQVIEEKMRGYFDNIFYLRLLRKVPSFFAGQHIPLGVEDGEMMIFFSFLLSHRILPLH
                     TMEYILGFGGQLADLLTQLIQEMKKEELLGDYTEDHVTYELSQLCAQVYLYKGYILQD
                     RYKYQLENRHPYLLMEHDFKETAEEIFHALPTFQQGTDLDKKILWEWLQLIEYMVENG
                     GQHMRIGLDLTSGFLVFSRMAAILKRYLEYNRFITIEAYDPSRHYDLLVTNNPIHKKE
                     QTPVYYLKNDLDMEDLAGIRQLLFT"
     gene            3591..5099
                     /gene="glpK"
                     /locus_tag="ACL29Z_001932"
     CDS             3591..5099
                     /gene="glpK"
                     /locus_tag="ACL29Z_001932"
                     /EC_number="2.7.1.30"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000076796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004370 - glycerol kinase activity
                     [Evidence IEA];
                     GO_process: GO:0006072 - glycerol-3-phosphate metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol kinase GlpK"
                     /protein_id="HGR0070187.1"
                     /translation="MSQEKYIMAIDQGTTSSRAIIFNKKGEKVSSSQKEFTQIFPQAG
                     WVEHNANEIWNSVQSVIAGAFIESGVKPNQIEAIGITNQRETTVVWDKKTGLPIYNAI
                     VWQSRQTAPLAEQLKSQGYVEKFHEKTGLIIDAYFSATKVRWILDHVEGAQERAEKGE
                     LLFGTIDTWLVWKLTDGAAHVTDYSNAARTMLYNIKELKWDDEILEILNIPKAILPEV
                     RSNSEIYGKTAPFHFYGGEVPISGMAGDQQAALFGQLAFEPGMVKNTYGTGSFIIMNT
                     GEEMQLSENNLLTTIGYGINGKVYYALEGSIFIAGSAIQWLRDGLRMVENSPESEKYA
                     RDSHNNDEVYVVPAFTGLGAPYWNQNARGSVFGLTRGTSKEDFIKATLQSIAYQVRDI
                     IDTMQVDTQTAIQVLKVDGGAAMNNFLMQFQADILGIDIARAKNLETTALGAAFLAGL
                     SVGYWKDLDELKLLNETGELFEPSMNESRKEQLYKGWKKAVKATQVFAEIDD"
     gene            5246..7072
                     /gene="glpO"
                     /locus_tag="ACL29Z_001933"
     CDS             5246..7072
                     /gene="glpO"
                     /locus_tag="ACL29Z_001933"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001865074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004368 - glycerol-3-phosphate
                     dehydrogenase (quinone) activity [Evidence IEA];
                     GO_process: GO:0006072 - glycerol-3-phosphate metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type 1 glycerol-3-phosphate oxidase"
                     /protein_id="HGR0070188.1"
                     /translation="MEFSKKTRELSIKKMQERTLDLLIIGGGITGAGVALQAAASGLE
                     TGLIEMQDFAEGTSSRSTKLVHGGLRYLKQFDVEVVSDTVSERAVVQQIAPHIPKPDP
                     MLLPVYDEDGATFSLFRLKVAMDLYDLLAGVSNTPTANKVLSKDQVLERQPNLKKEGL
                     VGGGVYLDFRNNDARLVIENIKRANQDGALIANHVKAEGFLFDESGKITGVVARDLLT
                     DQVFEIKARLVINTTGPWSDKVRNLSNKGTQFSQMRPTKGVHLVVDSSKIKVSQPVYF
                     DTGLGDGRMVFVLPRENKTYFGTTDTDYTGDLEHPKVTQEDVDYLLGIVNNRFPESNI
                     TIDDIESSWAGLRPLIAGNSASDYNGGNNGTISDESFDNLIATVESYLSKEKTREDVE
                     SAVSKLESSTSEKYLDPSAVSRGSSLDRDDNGLLTLAGGKITDYRKMAEGAMERVVDI
                     LKAEFDRSFKLINSKTYPVSGGELNPANVDSEIEAFAQLGVSRGLDSKEAHYLANLYG
                     SNAPKVFALAHSLEQAPGLSLVDTLSLHYAMRNELALSPVDFLLRRTNHMLFMRDSLD
                     SIVEPVLDEMGRFYDWTEEEKATYRADVEAALANNDLAELKN"
     gene            7142..7846
                     /locus_tag="ACL29Z_001934"
     CDS             7142..7846
                     /locus_tag="ACL29Z_001934"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262009.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015267 - channel activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MIP/aquaporin family protein"
                     /protein_id="HGR0070189.1"
                     /translation="MMNELFGEFLGTLILILLGNGVVAGVVLPKTKSNSSGWIVITMG
                     WGIAVAVAVFVSGKLSPAHLNPAVTIGVALKGGLPWASVLPYILAQFAGAMLGQILVW
                     LQFKPHYEAEENAGNILATFSTGPAIKDTVSNLISEILGTFVLVLTIFALGLYDFQAG
                     IGTFAVGTLIVGIGLSLGGTTGYALNPARDLGPRIMHSILPIPNKGDGDWSYAWIPVV
                     GPVIGAALAVLVFSLF"
BASE COUNT         2162 a         1563 c         1890 g         2233 t
ORIGIN      
        1 ttaagccttc tccaattgca agagggcttc aatctctgcc agggtgctag cttgcgaaat
       61 ggctccacgg agtttggcag cgccagatgt tccacggaga tagtgaggag cgaggccgcg
      121 gaattcacga actgcgacgt tttctccttt gaggttaatc aatcgtttca agtgttcgta
      181 ggcgatcttc atcttgtctt caaaggtcaa atcaggtagg atttctcctg tttcaaagta
      241 atggttgact tggttgaaga ggtaaggatt tcccatggca gctcggccaa tcatgactgc
      301 gtcagcacca acttcttcga tgcgttgctt ggcttcttgg acagtacgga tatcaccgtt
      361 ggcgatgaat ggaatcttgg ttagagcttg ggcaaccttg taaagggtct caaggtctgc
      421 gtggccagta tacatttgtt cacgggtacg gccatgcatg gcgagggcag aaacacctgc
      481 agcctcagca gcgagggcat tttctactgc aagagatggg tccgcccagc cggtacgcat
      541 tttgacagta agtgggatat caaggacaga ctggaccttg ttgatgatag agtagatctt
      601 gtcaggatcc ttgagccaca tagctccagc ttcgttcttc acgattttgt tgacagggca
      661 gcccatgttg atatcgacga tatcggtctt ggtgttttct tggataaatt ctgctgcgcg
      721 tgctaggctg tcttcatcgc taccaaaaag ttggatagag acagggtttt cgccctcatc
      781 gatatgaagc atgtgcaggg ttttttcgtt gttgtattgg attcccttgt cagagaccat
      841 ttccattaca acgagtccag ctccgagctc ttttgcgatg gtacgaaagg ctgagttggt
      901 cacgccagcc ataggcgcta aaacggtacg attgggaatc tcaacattgc caatcataaa
      961 aggtgtatta agatttgtca cgaatgagtt cctccaggtc cttttcatca aagttgtaag
     1021 tagtttggca gaattgacaa gtgatttcta ccccgtggtc ttcctctttc atttcctgta
     1081 agtctgagct tggaaggctg gcaagagcgt tcataaagcg ttcatggcta cagtcacatt
     1141 ggaaacggat ttcttcttca gaaagacgct tgtaggcttc gtccccgtag atagccttga
     1201 ggagggcttc gatatggtcg tcgctttcga gaagagtaga gatagctggc atttcttgga
     1261 tgcgtttttc aaagcgagca atctcttctt tcttggctcc tggcaagact tgaactagga
     1321 aaccacctgc aatcttgacc ttgtcttcct cgtccaaaag gacattgagg ccgaccgctg
     1381 aaggcgtttg ttggctttca gtaaggtaaa aggcaaggtc ttcaccgatt tctccagaga
     1441 tgaggggagt tatagagttg taaggatttc cagtaccgta gtctgtgata acgaggaatt
     1501 gaccatttcc aacaaaaggt ccgactagga cttcaccagt cgcagtcttt ttgatgtcaa
     1561 caccaggatt ttgaacgtag cctttgacgt tccccttggt atcagcgacg gtgataatag
     1621 cacctagaga gctagatccc aacaccttaa ctgtaagttt ggtatttcct ttttcattgg
     1681 ctgcgagaat ctggctggcg ataagagttc gaccaagcgc tacagttgag ctagcttggg
     1741 tttgatgttt ttcttgagca gtgcggacgg tttcagtgct atcaaggaca aaagcacgaa
     1801 aggctccgct ttctgatata gttttaataa ttttatccat agctactatt ttagcataaa
     1861 aatgcccaaa gggggagccg tgtgtttact gattttcagg ataatggacc aggaaatcag
     1921 catgaaaata aaaagagaaa cagattattt tagcatttgt aagatttatg ctatgcttaa
     1981 ggtagaaaat gaaaggggta acaaatgtat ttaggagatt tgatggagaa agccgagtgt
     2041 ggtcaatttt caatcctttc ctttctatta caagagtctc agacgaccgt caaggctgta
     2101 atggaagaaa caggattttc aaaagcaacc ctaaccaaat atgtcaccct gctcaatgac
     2161 aaggctttgg atagtggctt agagctggct attcactcag aagatgaaaa tctgcgtctg
     2221 tctatcggtg cagctaccaa ggggagagat attcggagct tgtttttgga gagtgctgtt
     2281 aaataccaga ttttggttta tcttctctac caccaacagt ttttagccca tcagctggct
     2341 caagaattgg tgattagcga ggctacgctt ggtcgtcact tggctggttt aaatcagatt
     2401 ttgtcagaat ttgatttatc catccaaaat ggacgttggc gaggtccaga gcatcagatt
     2461 cgctatttct atttctgtct tttccgaaag gtctggtcga gtcaggaatg ggaaggtcac
     2521 atgcagaaac cagagagaaa acaggagatt gccaatttag aggaaatctg cggtgcaagt
     2581 ttgtctgtgg ggcagaaatt ggacttggtt ctctgggctc acatcagtca acaacgtctt
     2641 cgggtcaatg cttgtcagtt tcaagtcata gaagagaaaa tgcgagggta ttttgacaat
     2701 atcttttatc ttcgtttgct gagaaaggtt ccgtcctttt ttgctgggca acatattcca
     2761 ctaggagttg aggatggtga gatgatgata ttcttctctt ttctcctatc tcatcgcatt
     2821 cttcctcttc atactatgga gtatattctt ggttttggag ggcagttggc agatttactg
     2881 acgcaattga ttcaagaaat gaagaaggag gaactattgg gggattatac agaggaccat
     2941 gtcacctatg aactcagtca gctttgtgct caagtctatc tctataaggg ctatatttta
     3001 caggatcgct acaagtacca gttagagaat cgtcatccat atttactgat ggaacatgat
     3061 tttaaagaga cagcagagga gatttttcat gctctaccta cttttcaaca ggggacagat
     3121 ttagataaga agattctctg ggaatggctc cagttaatcg aatatatggt tgaaaacggt
     3181 ggccagcata tgcggattgg tctggatttg acatctggtt ttcttgtctt ttcaaggatg
     3241 gcagccattt tgaaacggta tttggaatac aatcgtttta ttaccattga agcctatgac
     3301 cctagtaggc attatgattt gctggttacc aataacccta ttcataagaa ggaacagaca
     3361 ccagtctatt atttaaaaaa tgacttggat atggaagatt tggcagggat tcgtcagtta
     3421 ttattcactt aaaaggcttg gttaatccag gtcttttttg tgaaattcac acaatctcct
     3481 cacatttttt taaaaattaa aaaaagttga taaacaagaa agcgctttat tttgtatact
     3541 agtaagtgta aagaggaaac acctcaagat ctttatcagg aggacagtac atgtcacaag
     3601 aaaaatacat catggctatt gaccagggaa ctacaagttc tcgtgccatc attttcaaca
     3661 aaaaagggga aaaggttagc tcgagtcaaa aagagtttac ccagattttc cctcaggcag
     3721 gttgggttga gcacaatgcc aatgaaattt ggaactctgt tcagtcagtt attgcgggtg
     3781 ctttcattga aagtggtgtc aagccaaatc aaatcgaggc aatcgggatt accaaccaac
     3841 gtgaaacaac ggttgtctgg gataagaaaa caggacttcc tatctacaat gctatcgttt
     3901 ggcagtcacg ccagacagca cctttggctg agcaactaaa aagccaaggt tatgtggaaa
     3961 aattccatga aaagactggt ttgattattg atgcttactt ctctgctacc aaggttcgtt
     4021 ggattttgga tcatgtagaa ggtgctcaag agcgagcaga aaaaggggaa ttgctctttg
     4081 gtactatcga tacttggttg gtttggaaat tgactgacgg tgcggctcac gtgactgact
     4141 actcaaatgc agctcgtacc atgctttata acattaaaga actcaaatgg gatgatgaga
     4201 ttttggaaat ccttaacatt ccgaaggcta tacttccaga agttcgttct aactccgaaa
     4261 tctacggcaa gacagctcca ttccatttct acggtggaga ggtgccaatc tcaggtatgg
     4321 ctggggacca acaagcagcc ctctttggac agttggcttt tgagccaggt atggttaaga
     4381 atacttatgg aacaggctct ttcatcatca tgaatactgg ggaagagatg cagttgtctg
     4441 aaaacaacct cttgacaacc attggttacg gaatcaacgg taaggtttat tatgccttgg
     4501 aaggttctat cttcatcgca ggaagtgcta ttcagtggct tcgtgacggt cttcgcatgg
     4561 ttgaaaattc accagaatct gaaaaatacg ctcgtgattc tcacaacaac gatgaagttt
     4621 atgtcgttcc agcctttaca ggtctaggcg ctccatactg gaaccaaaat gctcgtggtt
     4681 ccgtctttgg tttgactcgt ggaacaagca aagaagactt tatcaaggcg actttgcaat
     4741 ctattgctta tcaagtgcgt gatatcatcg acaccatgca agtggatact cagaccgcca
     4801 ttcaagtact gaaggtggat ggtggtgcag ccatgaacaa cttcctcatg cagttccagg
     4861 cggatatttt aggcattgac attgcacgtg ctaaaaactt ggaaacaaca gctctaggag
     4921 cggccttcct agcaggtttg tcagtagggt actggaaaga cttggacgag ttgaaactct
     4981 tgaacgagac aggagaactc tttgagccat ctatgaacga atctcgcaag gaacaactct
     5041 acaagggctg gaagaaggct gtgaaagcaa ctcaagtctt tgcggaaatc gatgactaat
     5101 actcaatgaa aatcaaagag caaactagga agctagccgc aagctgtact tgagtacggt
     5161 aaggcgacgc tgacgtggtt tgaagagatt ttcgaagagt ataatactgg cagaataaag
     5221 cgatttagtt agaaagtgtg taaatatgga attttcaaag aaaacacgtg aattgtcaat
     5281 taaaaaaatg caggaacgca ccctggacct cttgattatc ggtggaggaa tcacaggagc
     5341 tggtgtagcc ttgcaggcgg cagctagcgg tcttgagact ggtttgattg aaatgcaaga
     5401 ctttgcagaa ggaacatcta gtcgttcaac aaaattggtt cacggaggac ttcgttacct
     5461 caaacaattt gacgtagaag tggtctcaga tacggtttct gaacgtgcag tggttcaaca
     5521 aatcgctcca cacattccaa aaccagatcc aatgctctta ccagtttacg atgaagatgg
     5581 agcaaccttt agcctcttcc gtcttaaagt agccatggac ttgtacgacc tcttggcagg
     5641 tgtgagcaac acaccaactg cgaacaaggt tttgagtaag gatcaagtct tggaacgcca
     5701 gccaaacttg aagaaggaag gcttggtagg aggtggagtg tatcttgact tccgtaacaa
     5761 cgatgcgcgt ctcgtgattg aaaacatcaa acgtgccaac caagacggtg ccctcattgc
     5821 caaccacgtg aaggcagaag gcttcctctt tgacgaaagt ggcaagatta caggtgttgt
     5881 agctcgtgat ctcttgacag accaagtatt tgaaatcaag gcccgtctgg ttattaatac
     5941 aacaggtcct tggagtgata aagtacgtaa tttgtctaat aagggaacgc aattctcaca
     6001 aatgcgccca actaagggag ttcacttggt agtggattca agcaaaatca aggtttcaca
     6061 gccagtttac tttgacacag gtttgggtga cggtcgtatg gtctttgttc tcccacgtga
     6121 aaacaagact tactttggta caactgatac agactacaca ggtgatttgg agcatccaaa
     6181 agtaactcaa gaagatgtag attatctact tggcattgtc aacaaccgct ttccagaatc
     6241 caacatcacc attgatgata tcgaaagcag ctgggcaggt cttcgtccat tgattgcagg
     6301 gaacagtgcc tctgactata atggtggaaa taacggtacc atcagtgatg aaagctttga
     6361 caacttgatt gcgactgttg aatcttatct ctccaaagaa aaaacacgtg aagatgttga
     6421 gtctgctgtc agcaagcttg aaagtagcac atctgagaaa tatttggatc catctgcagt
     6481 ttctcgtggg tctagcttgg accgtgatga caatggtctt ttgactcttg ctggtggtaa
     6541 aatcacagac taccgtaaga tggctgaagg agctatggag cgcgtggttg acatcctcaa
     6601 agcagaattt gaccgtagct ttaaattgat caattctaaa acttaccctg tttcaggtgg
     6661 agaattgaac ccagcaaatg tggattcaga aatcgaagcc tttgcgcaac ttggagtttc
     6721 acgtggtttg gatagcaagg aagctcatta cctagcaaat ctttacggtt caaatgcacc
     6781 gaaggtcttt gcacttgctc acagcttgga acaagcgcca ggtcttagct tggtagatac
     6841 tttgtccctt cactatgcaa tgcgcaacga gttggctctt agcccagttg acttccttct
     6901 tcgtcgtacc aaccatatgc tctttatgcg tgatagcttg gatagcatcg ttgagccagt
     6961 tttggatgaa atgggacgat tctatgactg gacagaagaa gaaaaagcaa cttaccgtgc
     7021 tgatgtcgaa gcagctctcg ctaacaacga tttagcagaa ttaaaaaatt aagaaaaaat
     7081 aaaagaggtg gagggcagca ttccttgtcg cccgtccctt ctttttaatg gagacagaaa
     7141 gatgatgaat gaattatttg gagaatttct agggacttta atcctgattc ttctaggaaa
     7201 tggtgttgtt gcaggtgtgg ttcttcctaa aaccaagagc aatagctcag gttggattgt
     7261 gattactatg ggttggggga ttgcagttgc ggttgcagtc tttgtatctg gcaagctcag
     7321 tccagctcat ttaaacccag ctgtgaccat cggtgtggcc ttaaaaggtg gtttgccttg
     7381 ggcttccgtt ttgccttata tcttagccca gttcgcaggg gccatgctgg gtcagatttt
     7441 ggtttggttg caattcaaac ctcactatga ggcagaagaa aatgcaggca atatcctggc
     7501 aaccttcagt actggaccag ccatcaagga tactgtatca aacttgatta gcgaaatcct
     7561 tggaaccttt gttttggtgt tgacaatctt tgctttgggt ctttacgatt ttcaggcagg
     7621 tatcggaacc tttgcagtgg gaactttgat tgtcggtatc ggtctatcac taggtgggac
     7681 aacaggttat gccttgaacc cagctcgtga ccttggacct cgtatcatgc acagcatctt
     7741 gccaattcca aacaagggag acggagactg gtcttacgct tggattcctg ttgtaggccc
     7801 tgttatcgga gcagccttgg cagtgcttgt attctcactt ttctagtt
//
LOCUS       DBEJAU010000072         7260 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC323 isolate 683620
            SAMN38261939-rid24807223.denovo.072, whole genome shotgun sequence.
ACCESSION   DBEJAU010000072 DBEJAU010000000
VERSION     DBEJAU010000072.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261939
            Sequence Read Archive: SRR26833919
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 7260)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7260)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576303.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576303.1
            Genome Coverage       :: 154x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/19/2025 01:05:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,121
            CDSs (total)                      :: 2,078
            Genes (coding)                    :: 1,943
            CDSs (with protein)               :: 1,943
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 36
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 72 of 135
            Pseudo Genes (incomplete)         :: 63 of 135
            Pseudo Genes (internal stop)      :: 51 of 135
            Pseudo Genes (multiple problems)  :: 46 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7260
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261939-rid24807223.denovo.072"
                     /strain="GPSC323"
                     /isolate="683620"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            244..948
                     /locus_tag="ACL29Z_001935"
     CDS             244..948
                     /locus_tag="ACL29Z_001935"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001033172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009055 - electron transfer activity
                     [Evidence IEA];
                     GO_function: GO:0010181 - FMN binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin family protein"
                     /protein_id="HGR0070190.1"
                     /translation="MNKIFIYAGVRNHNSKTLEYTKRLSSIISSRNNVDISFRTPFNS
                     ELEISNSDSEELFKKGIDRQSNADDGGVIKKELLESDIIIISSPVYLQNVSVDTKNFI
                     ERIGGWSHLFRLAGKFVVTLDVAESNGSDNVSEYLRDIFSYMGGQILHQVSITNSLKD
                     IAEAQLMEATYKIEDVLEGKIKYKTTDYQERAYQTLKLILENYDSEHFEKMYWEKKRL
                     FEANSLEEWYYVENIK"
     gene            929..1858
                     /locus_tag="ACL29Z_001936"
     CDS             929..1858
                     /locus_tag="ACL29Z_001936"
                     /EC_number="3.4.24.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000912951.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0004222 - metalloendopeptidase activity
                     [Evidence IEA];
                     GO_function: GO:0008233 - peptidase activity [Evidence
                     IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="M50 family metallopeptidase"
                     /protein_id="HGR0070191.1"
                     /translation="MLKILNNSVIYLCLIPLLFLLLIIFPNDSLIYYFRLILISLISI
                     TLHELGHFLVGRCLSYKLEMLATPFFFYFRKKIYFKFPVLLAFGYCQMSNRNITNEKN
                     SDRNLVFYFFGGGGANLIVAILALLGFVPYASEFFILNIILFLVTVCLPIDGTDGNAI
                     REIVLYSKDSKTYQRFFANSLYNNPYITIDDFAKLTSKEKSFFSKFEKCLINLYFEVK
                     GEGSAFTIANHEVFDSNIQENIIHEYYKLLHKSSDWIIPQNLSLEEVVFTLSNYIYSK
                     NNKYLEKIKYLKKLVDFRQEEIIDFILNKEEVL"
     gene            1855..3963
                     /locus_tag="ACL29Z_001937"
     CDS             1855..3963
                     /locus_tag="ACL29Z_001937"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000701297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008233 - peptidase activity [Evidence
                     IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase domain-containing ABC transporter"
                     /protein_id="HGR0070192.1"
                     /translation="MKIPMIYQMENSECGLACCAMILNYFKYEISLNELREIYPSSRS
                     GYSLLSISKVLGDFNISSHAFKASVRDLKPLSFPLICFWESSHFIILEKISKNKFYIL
                     DPAKGRQRMSISEFERHYSNIILTFKKLDSFMSRKDNKKSPVLKYFFKYRNKLGILFF
                     VTALLYVIQSLVPIANRYIIDTNFKDDSYSSRMLFTILFIFTVSFSLMYLLRQIYVAS
                     LKYIMDKEISYDFMKHLIYLPYSFYEKRTLGDILFRANSIVYIREILSNNFIAAILDL
                     LMIVVYAVVLFSFSKYMVIFLISLSLALSIVMYPIIKISKNLIDKNIKEKVNVQNITS
                     EVISKNSDIKLTGEEEFWINKWDNFNTKQLIIGRKLDIHLSIVSSITNVLQIILPVLT
                     LIVGVNIKTFEQLTLGQIVAISTVSPYFISPIISLSDNYIQLMLLKGYFLRIEDVFNT
                     KSELIPERVSQDIKFDKKIELKDIWYKYGLFDDYVLKGINVTIKKGETVAIVGESGSG
                     KSTLAKILLGLLEPNIGSIEVDGVEKEEIGQTLYRKIFGAVLQNSTLSYGTLRENLTF
                     GHFVSDEELMTNLNSIGLSNVVKSLPLGLETIIAEEGNNFSGGQQQMILLARCLLSKP
                     SVVVLDEATSSLDNLSQQITTSYLSEIGTTKILIAHRLDTIKSADKILVMHNGEIVEI
                     GTHRELLELGGIYKQLYSNN"
     gene            3987..5726
                     /locus_tag="ACL29Z_001938"
     CDS             3987..5726
                     /locus_tag="ACL29Z_001938"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000699970.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008236 - serine-type peptidase activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="S8 family serine peptidase"
                     /protein_id="HGR0070193.1"
                     /translation="MKIMKKKYWTLAILFFCLFNNSVTAQEIPKNLDGNITHTQTSES
                     FSESDEKQVDYSNKNQEEVDQNKFRIQIDKTELFVTTDKHLEKNCCKLELEPQINNDI
                     VNSESNNLLGEDNLDNKIKENVSHLDNRGGNIEHDKDNLESSIVRKYEWDIDKVTGGG
                     ESYKLYSKSNSKVSIAILDSGVDLQNTGLLKNLSNHSKNYVPNKGYLGKEEGEEGIIS
                     DIQDRLGHGTAVVAQIVGDDNINGVNPHVNINVYRIFGKSSASPDWIVKAIFDAVDDG
                     NDIINLSTGQYLMIDGEYEDGTNDFETFLKYKKAIDYANQKGVIIVAALGNDSLNVSN
                     QSDLLKLISSRKKVRKPGLVVDVPSYFSSTISVGGIDRLGNLSDFSNKGDSDAIYAPA
                     GSTLSLSELGLNNFINAEKYKEDWIFSATLGGYTYLYGNSFAAPKVSGAIAMIIDKYK
                     LKDQPYNYMFVKKILEETLPVKNGIKVLNIPNVLRYDLNMLQLEYKNEQSWDSFIDNV
                     NLIELEERIQTTIGIKQINTHNIITIAREGYSQNYLPNTSENTYNSLQVSLVGVLLLF
                     ISMVNILWAKKSK"
     gene            5777..6544
                     /locus_tag="ACL29Z_001939"
     CDS             5777..6544
                     /locus_tag="ACL29Z_001939"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1430 domain-containing protein"
                     /protein_id="HGR0070194.1"
                     /translation="MSQKMNHLDVGEFVLLLPEHLRSEEEHYKSVFEDDLTSRISSQD
                     ERQQMTATVGYLESGQDRFVYNTTPISYQQFLKDPIIIVITPQSTGPQSILFWIDAVQ
                     NYVLFNQLSDAQELIQRQGIENWVSEMQTGYHNYITLLDNIQRERWVMLAGAVLGIAT
                     SILLFNTMNRLYFEEFRRAIFIKRIAGLRFLEIHRTYLFAQLGVFLLGFVASVFLQVE
                     IGVAFLVLLLFTGLSLLQLHVQMQKENKMSMLVLKGG"
     gene            6546..7178
                     /locus_tag="ACL29Z_001940"
     CDS             6546..7178
                     /locus_tag="ACL29Z_001940"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGR0070195.1"
                     /translation="MIELKQVSKSFGERELFSNLSMTFEAGKVYALIGSSGSGKTTLM
                     NMIGKLEPYDGTIFYRGKDLANYKSSDSFRHELGYLFQNFGLIENQSIEENLKLGLIG
                     QKLSRSEQRLRQKQALEQVGLVYLDLDKRIFELSGGESQRVALAKIILKNPPFILADE
                     PTASIDPATSQLIMEILLSLRDDNRLIIIATHNPAIWEMADEVFTMDHLK"
BASE COUNT         2586 a          952 c         1290 g         2432 t
ORIGIN      
        1 agtgtagctt ttcgttgaga taataatata ataaagaaaa gttctattct aattgctaaa
       61 cggcttgagg tatatgctac tgttatagaa atgattttaa actaaaatca aaattactcc
      121 aaaaatagta ttgattttgg tttaatacaa aacatatgta ataatgtgag tcaacaaaag
      181 tctgtttttg taccatacta tcttgaaaaa tctactaaat tcaaattgag aggatgaatt
      241 aaaatgaata aaatatttat atatgcagga gtgcgaaatc ataactctaa gactttagag
      301 tatactaaga gactttcaag tatcatttct agtagaaata atgttgatat atctttcagg
      361 acacctttca attcagagct agaaatatct aattctgatt cagaagagtt gtttaagaaa
      421 ggaattgata ggcaaagtaa tgctgatgat ggaggtgtta taaaaaaaga gttattagag
      481 tctgatatta taattatctc ttctcctgta tatttacaaa acgtatctgt ggacacaaaa
      541 aactttattg aaaggattgg ggggtggagc catctttttc gattagctgg aaagtttgtt
      601 gtaacattag atgttgctga gagtaacggc tctgataatg tgtcagaata tcttagagat
      661 atattttcat atatgggagg acagatatta caccaagttt caattaccaa ttcactcaaa
      721 gatattgcag aggctcagtt gatggaggca acttataaaa ttgaagatgt acttgaaggg
      781 aaaattaagt acaaaacaac ggattatcaa gaaagagctt accagacatt aaaattaatt
      841 ttagaaaatt atgattccga acattttgag aagatgtatt gggagaaaaa acgccttttt
      901 gaagctaata gtttagagga atggtattat gttgaaaata ttaaataact ctgtcatata
      961 tttatgtttg attccgttat tgttcctatt attgataatt tttccaaatg attcattaat
     1021 ctattatttt cgattgattt taatttcgtt aatatcaatt acattacatg aactaggtca
     1081 ttttttagtg ggaagatgtt tatcttataa actagagatg cttgctactc cctttttctt
     1141 ctatttcaga aaaaaaatat atttcaaatt tccagtgtta ttagcattcg gttattgtca
     1201 aatgagtaat agaaacatta ctaatgaaaa aaatagtgat aggaatttgg tgttctactt
     1261 ctttggggga ggtggagcta acctaattgt cgcaatatta gcacttttgg gatttgtgcc
     1321 gtacgcatca gaatttttta ttttgaatat aattcttttt ctagttacgg tatgtttacc
     1381 aattgatgga acagatggca atgctattag agagatagtt ttgtattcaa aagattcaaa
     1441 aacatatcag agattctttg cgaacagtct ctataataat ccttatataa caatcgacga
     1501 ttttgcaaaa ttaacctcta aagaaaaatc ttttttttca aaatttgaaa aatgtttgat
     1561 aaacctttac tttgaagtga aaggtgaagg gtcagcattt acaattgcta atcatgaagt
     1621 ttttgattca aatattcagg aaaatattat ccatgagtac tataaattac tacataaatc
     1681 ttctgattgg attattccac agaacttatc tttagaagaa gttgttttta ccttgtcaaa
     1741 ctatatttac tcgaaaaata ataaatattt agaaaagatt aagtatctaa agaaattagt
     1801 agattttaga caagaagaaa ttatcgactt tattttgaac aaggaggaag tattgtgaaa
     1861 attccaatga tatatcaaat ggaaaattca gaatgtggat tagcatgctg tgccatgata
     1921 ttgaactatt ttaaatatga gatttcttta aatgaactac gtgaaatcta cccatcatcc
     1981 agatctggat attctctcct atctataagt aaagttttag gagattttaa tataagttct
     2041 catgctttta aagcttcggt aagagattta aaaccgctca gtttcccact catttgcttc
     2101 tgggagagtt ctcattttat tattcttgaa aaaattagta aaaacaagtt ttatatttta
     2161 gatcctgcaa aaggcaggca gagaatgtca ataagtgaat ttgaaaggca ttattcaaat
     2221 atcattttaa catttaaaaa gttagatagc tttatgtctc gtaaagataa taagaagtcg
     2281 cctgttttaa agtatttttt taagtatagg aataagctag ggattttatt ttttgtaaca
     2341 gcattattgt atgtaataca atcattagta cctatagcta atagatacat aattgacacg
     2401 aatttcaagg acgattcgta ttcgtctaga atgttattta ctatattatt tatatttact
     2461 gtttcattct cactaatgta tttattaaga cagatatatg ttgcatcctt aaaatatata
     2521 atggataaag agattagcta tgattttatg aaacatttga tatatttacc ttacagtttt
     2581 tatgaaaaac gtactttagg ggatatactt tttagagcta actctattgt ttatataaga
     2641 gaaatactat caaataattt tatagcagct atacttgatt tgttaatgat tgtggtttat
     2701 gctgtggttt tatttagctt ttctaagtac atggtaatct ttttaatatc actaagtcta
     2761 gctctatcta ttgtaatgta tccaatcata aaaatctcaa aaaatttaat tgataaaaat
     2821 ataaaagaaa aggttaatgt tcaaaatatt acttccgaag taatttctaa aaatagtgat
     2881 attaagctaa ctggagaaga ggaattttgg attaacaaat gggataattt taatacaaaa
     2941 cagctcatca taggtcgaaa acttgatata catttatcaa ttgttagtag tataacgaat
     3001 gttttacaaa ttattctccc tgttttgacc cttattgtag gtgtaaatat aaaaacattc
     3061 gaacaattga cgttaggaca aattgtagca ataagtacag tctcaccata ctttatttct
     3121 cctataattt ctttaagtga taactatata caattaatgt tattaaaggg atatttttta
     3181 agaatagagg atgtgtttaa tactaaatcc gaattaattc cagaaagagt cagtcaagat
     3241 ataaaatttg ataaaaaaat agaattaaaa gatatttggt ataaatatgg attatttgat
     3301 gattatgttt tgaaaggaat aaatgttact attaaaaaag gagaaactgt tgctattgtt
     3361 ggagaatcag gttcaggtaa gagtacatta gctaaaattt tattaggttt attagaacct
     3421 aatattggtt caatagaagt tgatggagta gaaaaagaag aaattggtca aacattgtat
     3481 agaaagattt ttggagcagt gttacaaaat tcaaccctaa gttatggtac cttaagagag
     3541 aatttgacat ttggacactt tgtttcagat gaagaattaa tgacaaatct aaattcaatt
     3601 ggtcttagca atgtagttaa atctttacct cttggattag agacaatcat cgctgaagaa
     3661 ggtaataact tttctggagg gcagcagcaa atgatacttt tagctcgttg tcttttgtcg
     3721 aaaccttcgg tagttgtttt ggacgaagca acaagtagtt tagataattt atctcaacaa
     3781 attacaactt cttacttaag tgaaatcggt accactaaga ttttaattgc ccatcgacta
     3841 gatactatca agtctgcaga taagatctta gtaatgcata atggtgaaat tgtagagatt
     3901 gggacccata gagaacttct tgaactagga ggcatttata agcaattgta ttcaaataat
     3961 tagtttttga ttaaaagggt aaatttatga agattatgaa aaaaaaatat tggactttag
     4021 cgatattatt cttttgtttg ttcaataatt ctgttactgc tcaagaaata cctaaaaatc
     4081 ttgatggcaa tataactcac actcagacta gcgaaagttt ttctgaatct gatgaaaaac
     4141 aggttgacta ttctaataaa aatcaagaag aagtagacca aaataaattt cgtattcaaa
     4201 tcgataagac agaattattt gtaacaacag ataaacattt agaaaaaaac tgttgtaaat
     4261 tggaacttga accacaaata aataacgata ttgttaactc tgaaagtaat aatttactag
     4321 gcgaagataa tttagataat aaaattaagg aaaatgtttc tcatctagat aatagaggag
     4381 gaaatataga gcatgacaaa gataacttag aatcgtcgat tgtaagaaaa tatgaatggg
     4441 atatagataa agttactggt ggaggcgaaa gttataaatt atattctaaa agtaattcta
     4501 aagtttcaat tgctatttta gattcaggag tcgatttaca aaatactgga ttactgaaaa
     4561 atctttcaaa tcactcaaaa aactatgtcc ccaataaagg atatttagga aaagaggagg
     4621 gagaggaagg aataatatca gatattcaag atagattagg tcatggtacg gctgttgtag
     4681 ctcaaattgt aggggatgac aatattaatg gagtaaatcc tcacgttaat attaacgtct
     4741 atagaatatt tggtaagtcg tcagctagtc cagattggat tgtaaaagca atttttgatg
     4801 ctgtagatga tggcaatgat attatcaatc ttagtactgg acaatattta atgattgatg
     4861 gagaatatga ggacggaaca aatgattttg aaacattttt gaagtataaa aaggctattg
     4921 attacgcgaa tcaaaaagga gtaattatag tagctgcatt agggaatgac tccctaaatg
     4981 tatcaaatca gtcagattta ttgaaactta ttagttcacg caaaaaagta agaaaaccag
     5041 gattagtagt tgatgttcca agttatttct catctacaat ttcggtcgga ggcatagatc
     5101 gcttaggtaa tttatcagat tttagcaata aaggggattc tgatgcaata tatgcgcctg
     5161 caggctcaac attatctctt tcagaattag gacttaataa ctttattaat gcagaaaaat
     5221 ataaagaaga ttggattttt tcggcaacac taggaggata tacgtatctt tatggaaact
     5281 catttgctgc tcctaaagtt tctggtgcga ttgcaatgat tattgataaa tacaaattaa
     5341 aagatcagcc ctataattat atgtttgtaa aaaaaattct ggaagaaaca ttaccagtaa
     5401 aaaatggtat aaaagtgtta aatataccaa acgtattgag atatgatttg aatatgttac
     5461 aattagaata taaaaatgaa caaagttggg atagtttcat agataatgtt aatttaattg
     5521 agttggaaga gagaattcaa actactattg gaattaaaca aataaacaca cacaatatta
     5581 ttactattgc ccgagaaggg tactctcaaa attatttacc taacacttca gaaaatacat
     5641 ataattcatt acaagtcagt ttagttggag tattactact ttttataagt atggtaaata
     5701 ttttatgggc taaaaaaagt aaatgaaaat aaaatttgga gccctctgaa aaagtaagtc
     5761 ctacagttca actaaaatga gtcaaaagat gaatcacctt gatgtagggg agtttgtctt
     5821 attgctgcct gaacacctcc gttcagagga agaacattat aaatctgttt ttgaagacga
     5881 cttaaccagt cgcatatcta gtcaagatga acgacagcaa atgactgcta cggtaggtta
     5941 tttagaatca ggtcaggatc gttttgtgta taatacgacc cctatttctt accagcagtt
     6001 tttgaaagat ccaatcatca ttgttataac accccaatca actggtccac agtccatttt
     6061 gttttggata gacgcagtac agaactacgt tctctttaat caattgtctg atgcccagga
     6121 gcttatccag agacaaggca ttgaaaattg ggtctcagaa atgcaaacag gttaccacaa
     6181 ctacatcaca ttattggata atatccagag ggaacgttgg gtaatgctag caggagctgt
     6241 gcttgggatt gcaacttcaa tcttgttgtt taacactatg aataggctct actttgaaga
     6301 atttagacgt gccattttta tcaaacgcat tgcaggtctc aggttcttag aaatccatcg
     6361 cacttatctc tttgctcaac tgggtgtgtt tttactggga tttgttgcga gtgtatttct
     6421 tcaggtagag ataggagttg ctttcttagt cttgttactc tttactggtc tatctctttt
     6481 acagttacat gtccaaatgc agaaagaaaa caagatgtcc atgcttgttt tgaagggagg
     6541 ttaatatgat tgaacttaaa caggtgagta aatcttttgg agaacgagag ttattttcga
     6601 atctttcaat gacatttgag gctggaaaag tctatgcctt aattggttca agtggtagcg
     6661 gaaaaacaac cttgatgaac atgattggga aattagaacc ttatgatggg acgatttttt
     6721 accgaggtaa agacttggcc aattataaat caagtgattc tttccgtcac gaattgggct
     6781 acctcttcca gaactttggc ttaattgaaa accaaagtat tgaagaaaac cttaagctag
     6841 gtctcattgg tcaaaagttg agtcggtcgg aacagcggtt gaggcagaag caggctttag
     6901 aacaggtcgg cctggtttat cttgacctag ataagcgcat ctttgagtta tcgggcggag
     6961 aatcgcaacg ggttgccttg gcaaaaatta tcttaaagaa tccacccttt attctggcag
     7021 atgagccaac agcttcaata gacccagcaa cctctcagtt gattatggag attttgctat
     7081 ctcttcgaga tgataatagg ctaatcatta tcgcaacaca taatccggca atttgggaga
     7141 tggctgatga agtgttcacg atggatcatc tgaaataaaa atccttgttt ttaattgcac
     7201 gatgagttac tgaaatatta tcatgaatca agaattggag ttaatttaga attgtactta
//
LOCUS       DBEJAU010000073         6963 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC323 isolate 683620
            SAMN38261939-rid24807223.denovo.073, whole genome shotgun sequence.
ACCESSION   DBEJAU010000073 DBEJAU010000000
VERSION     DBEJAU010000073.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261939
            Sequence Read Archive: SRR26833919
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 6963)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6963)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576303.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576303.1
            Genome Coverage       :: 154x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/19/2025 01:05:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,121
            CDSs (total)                      :: 2,078
            Genes (coding)                    :: 1,943
            CDSs (with protein)               :: 1,943
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 36
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 72 of 135
            Pseudo Genes (incomplete)         :: 63 of 135
            Pseudo Genes (internal stop)      :: 51 of 135
            Pseudo Genes (multiple problems)  :: 46 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6963
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261939-rid24807223.denovo.073"
                     /strain="GPSC323"
                     /isolate="683620"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            1..555
                     /locus_tag="ACL29Z_001941"
                     /pseudo
     CDS             1..555
                     /locus_tag="ACL29Z_001941"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="internal stop; incomplete; missing N-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            616..1578
                     /locus_tag="ACL29Z_001942"
     CDS             616..1578
                     /locus_tag="ACL29Z_001942"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FtsX-like permease family protein"
                     /protein_id="HGR0070196.1"
                     /translation="MNMSNITIDGQEMDLSQTMPSYAQVVSLYDDTSISVSNNETDKV
                     LAGSLYTDTNEQGLTIPSSLLKNWNEQTGKNLTANDLIGKSVSASIVESAAETSKIAQ
                     FQTKIVRVINDEDDMEDSNSFMLSHQMETILKEAGFTKAVSYFILELKDPSQTKVVTE
                     ELQKNKKYTVLSQQRVLDIVITFIRVIQGLLIVLSSQAIVVAAVMIGIIIYINIMQRS
                     KEIGVMKAVGYQNRDVKGIFIYEAIWIVGIALLLAFLVAQGVGSLANAIVSHFYPSIT
                     KVFELNLLSVLGTLVFALLLGYVSAYFPARKISKMDPVESLRYE"
     gene            1755..2762
                     /gene="gap"
                     /locus_tag="ACL29Z_001943"
     CDS             1755..2762
                     /gene="gap"
                     /locus_tag="ACL29Z_001943"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008090210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016620 - oxidoreductase activity, acting
                     on the aldehyde or oxo group of donors, NAD or NADP as
                     acceptor [Evidence IEA];
                     GO_function: GO:0050661 - NADP binding [Evidence IEA];
                     GO_function: GO:0051287 - NAD binding [Evidence IEA];
                     GO_process: GO:0006006 - glucose metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type I glyceraldehyde-3-phosphate dehydrogenase"
                     /protein_id="HGR0070197.1"
                     /translation="MVVKVGINGFGRIGRLAFRRIQNVEGVEVTRINDLTDPVMLAHL
                     LKYDTTQGRFDGTVEVKEGGFEVNGKFVKVSAERDPEQIDWATDGVEIVLEATGFFAK
                     KEAAEKHLKGGAKKVVITAPGGNDVKTVVFNTNHDVLDGTETVISGASCTTNCLAPMA
                     KALQDNFGVVEGLMTTIHAYTGDQMILDGPHRGGDLRRARAGAANIVPNSTGAAKAIG
                     LVIPELNGKLDGSAQRVPTPTGSVTELVAVLEKNVTVDEVNAAMKAASNESYGYTEDP
                     IVSSDIVGMSYGSLFDATQTKVLDVDGKQLVKVVSWYDNEMSYTAQLVRTLEYFAKIA
                     K"
     gene            complement(2829..3704)
                     /locus_tag="ACL29Z_001944"
     CDS             complement(2829..3704)
                     /locus_tag="ACL29Z_001944"
                     /EC_number="5.4.99.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0009982 - pseudouridine synthase activity
                     [Evidence IEA];
                     GO_process: GO:0001522 - pseudouridine synthesis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HGR0070198.1"
                     /translation="MQFTFTLPASLPQMTVKQLLEEQLLIPRKIRHFLRIKKHILINQ
                     EEVHWNEIVNPGDVCQLTFDEEDYSQKTIPWGNPDLVQEVYQDQHLIIVNKPEGMKTH
                     GNQPNEIALLNHVSTYVGQTCYVVHRLDMETSGLVLFAKNPFILPILNRLLEKKEISR
                     EYWALVDGNINRKELVFRDKIGRDRHDRRKRIVDAKNGQYAETHVSRLKQFSNKTSLA
                     RCKLKTGRTHQIRVHLSHHNLPILGDPLYNSKSKTSRLMLHAFRLSFTHPLTLEKLTF
                     TTLSNTFEKELKKNG"
     gene            3791..5986
                     /gene="pbp2a"
                     /locus_tag="ACL29Z_001945"
     CDS             3791..5986
                     /gene="pbp2a"
                     /locus_tag="ACL29Z_001945"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000762602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008658 - penicillin binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein PBP2A"
                     /protein_id="HGR0070199.1"
                     /translation="MKLDKLFEKFLSLFKKETSELEDSDSTILRRSRSDRKKLAQVGP
                     IRKFWRRYHLTKIILILGLSAGLLVGIYLFAVAKSTNVNDLQNALKTRTLIFDREEKE
                     AGALSGQKGTYVELTDISKNLQNAVIATEDRSFYKNDGINYGRFFLAIVTAGRSGGGS
                     TITQQLAKNAYLSQDQTVERKAKEFFLALELSKKYSKEQILTMYLNNAYFGNGVWGVE
                     DASKKYFGVSASEVSLDQAATLAGMLKGPELYNPLNSVEDSTNRRDTVLQNMVAAGYI
                     DKNQETEAAEVDMTSQLHDKYEGKISDYRYPSYFDAVVNEAVSKYNLTEEEIVNNGYR
                     IYTELDQNYQANMQIVYENISLFPRAEDGTFAQSGSVALEPKTGGVRGVVGQVADNDK
                     TGFRNFNYATQSKRSPGSTIKPLVVYTPAVEAGWALNKQLDNHTMQYDSYKVDNYAGI
                     KTSREVPMYQALAESLNLPAVATVNDLGVDKAFEAGEKFGLNMEKVDRVLGVALGSGV
                     ETNPLQMAQAYAAFANEGLMPEAHFISRIENASGQVIASHKNSQKRVIDKSVADKMTS
                     MMLGTFTNGTGISSSPADYIMAGKTGTTEAVFNPEYTSDQWVIGYTPDVVISHWLGFP
                     TTDENHYLAGSTSNGAAHVFRNIANTILPYTSGSTFTVENAYKQNGIAPANTKRQVQT
                     NDNSQTDDNLSDIRGRAQSLVDEASRAISDAKIKEKAQTIWDSIVNLFR"
     gene            6039..6191
                     /gene="rpmG"
                     /locus_tag="ACL29Z_001946"
     CDS             6039..6191
                     /gene="rpmG"
                     /locus_tag="ACL29Z_001946"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015912025.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HGR0070200.1"
                     /translation="MALKKASLACAVCGSRNYSIKISGNPKPTRLEVNKFCKHCGKYT
                     THRETR"
     gene            6201..6377
                     /gene="secE"
                     /locus_tag="ACL29Z_001947"
     CDS             6201..6377
                     /gene="secE"
                     /locus_tag="ACL29Z_001947"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001211016.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0015450 - protein-transporting ATPase
                     activity [Evidence IEA];
                     GO_process: GO:0009306 - protein secretion [Evidence IEA];
                     GO_process: GO:0043952 - protein transport by the Sec
                     complex [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecE"
                     /protein_id="HGR0070201.1"
                     /translation="MRFIGDIFRLLKDTTWPTRKESWRDFRSIMEYTAFFVVIIYIFD
                     QLIVSGLIRFINIF"
     gene            6432..>6963
                     /gene="nusG"
                     /locus_tag="ACL29Z_001948"
     CDS             6432..>6963
                     /gene="nusG"
                     /locus_tag="ACL29Z_001948"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000376740.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0032784 - regulation of DNA-templated
                     transcription elongation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination/antitermination
                     protein NusG"
                     /protein_id="HGR0070202.1"
                     /translation="MDSFDKGWFVLQTYSGYENKVKENLLQRAQTYNMLDNILRVEIP
                     TQTVQVEKNGKRKEVEENRFPGYVLVEMVMTDEAWFVVRNTPNVTGFVGSHGNRSKPT
                     PLLEQEIRDILVSMGQTVQEFDFDVEIGQTVRIIDGAFADYTGKITEIDNNKVKMIIS
                     MFGNDTVAEVNLNQIAE"
BASE COUNT         2174 a         1214 c         1497 g         2078 t
ORIGIN      
        1 tgggctacac tcgaaaaaaa gaaccacacc tactatgaac aagacccaga aaaaatagcc
       61 ttatttctta aaaattttaa tagtttaaag cacctagcac ctgtttagat tgatgaaaca
      121 ggattcgata cttattttta tcgagaatat ggtcgctcat taaaaggtca gttaatatga
      181 ggcaaagtat ctggaagaag atatcagagg atttctttgg ttgcaggtct aacaaatggt
      241 gaattaatcg ctccaatgac ttacgaagag atgatgacga gcgacttttt tgaagtatgg
      301 tttcagaagt ttttcttacc aacattaacc acaccatcgg ttattattat ggataatgca
      361 agattccata gaatgggtaa gttagaactc ttgtgtgaag agtttgggca taaactttta
      421 cctcttcctc cctactcacc tgagtacaat cctattgaga aaacatgggc tcatatcaaa
      481 aagcacctca aaaaggtatt accaagttgc aatacctttt acgaggcttt tttatcctgc
      541 tcttgtttca attgactata gttcacggat acagttggga aagaagctat taaatatttg
      601 gagagtcctt ttgggatgaa catgtcaaat attactatag atgggcaaga aatggatctg
      661 agtcaaacga tgccttctta tgctcaagta gtgagtcttt atgatgatac aagtatctct
      721 gttagtaata atgagacgga caaagtgttg gctggctccc tctatactga tacaaatgaa
      781 cagggattaa cgattccaag cagtttacta aaaaattgga atgaacagac aggaaaaaat
      841 ttgacagcta atgatcttat tggcaaatca gtctcagcca gcattgtaga aagtgctgcc
      901 gaaactagta agattgctca atttcaaacg aagattgtac gtgtaattaa tgatgaagat
      961 gacatggagg acagcaacag tttcatgctg tctcatcaaa tggaaacgat tttgaaagag
     1021 gctggattta cgaaagctgt gtcttatttt atcttggaac tcaaagatcc atcacagaca
     1081 aaagtagtaa cagaagaatt acagaaaaat aagaagtata ctgtgctttc tcaacagaga
     1141 gttcttgata ttgtgattac ctttattcgt gttattcagg gattattgat tgtgctttca
     1201 tcacaagcta ttgtggtagc agcggttatg attggtatca ttatttacat caatatcatg
     1261 caacgttcca aggaaatagg tgtcatgaaa gcagttggtt atcagaatcg tgatgtcaaa
     1321 ggaattttta tttacgaggc tatctggatt gtaggcatcg ccttgctgct ggcatttttg
     1381 gttgcacaag gggtgggaag tttggcgaat gcgattgtaa gtcactttta cccatccatc
     1441 actaaggttt ttgaattaaa tcttttatct gttttaggaa ctctagtttt cgctctatta
     1501 cttggttatg tctcagccta cttcccggcg cgtaagatta gtaaaatgga tcctgtagaa
     1561 tcgttacgct atgaataata agggattcct tgatttacag tcttaaaaag aaactcacat
     1621 agaaaaacaa tggccatact tgcaattcaa ctcaaatagt tgtataatag gtttgttgaa
     1681 aggtgatttg tagtgattca agttactctt ttcacaataa aaatttcatg attttcataa
     1741 ggaggaaatc actaatggta gttaaagttg gtattaacgg tttcggacgt atcggtcgtc
     1801 ttgctttccg tcgtatccaa aacgtagaag gtgttgaagt tacacgcatc aacgacctta
     1861 cagatccagt tatgcttgca cacttgttga aatacgacac aactcaaggt cgtttcgacg
     1921 gtactgttga agttaaagaa ggtggattcg aagttaacgg taaattcgtt aaagtttctg
     1981 ctgaacgtga tccagagcaa atcgactggg ctactgacgg tgtagaaatc gttcttgaag
     2041 ctactggttt ctttgctaag aaagaagcag ctgaaaaaca ccttaaaggt ggagctaaaa
     2101 aagttgttat cactgctcct ggtggaaacg acgttaaaac agttgtattc aacactaacc
     2161 acgacgttct tgacggtact gaaacagtta tctcaggtgc ttcatgtact acaaactgct
     2221 tggctccaat ggctaaagct cttcaagata actttggtgt tgttgaagga ttgatgacta
     2281 ctatccacgc ttacactggt gaccaaatga tccttgacgg accacaccgt ggtggtgacc
     2341 ttcgccgtgc tcgcgctggt gctgcaaaca tcgttcctaa ctcaactggt gctgctaaag
     2401 ctatcggtct tgtaatccca gaattgaacg gtaaacttga cggatctgca caacgcgttc
     2461 caactccaac tggatcagtt actgaattgg tagcagttct tgaaaagaac gttactgttg
     2521 atgaagtgaa cgcagctatg aaagcagctt caaacgaatc atacggttac acagaagatc
     2581 caatcgtatc ttcagatatc gtaggtatgt cttacggttc attgtttgac gcaactcaaa
     2641 ctaaagttct tgacgttgac ggtaaacaat tggttaaagt tgtatcatgg tacgacaacg
     2701 aaatgtcata cactgcacaa cttgttcgta ctcttgaata cttcgcaaaa attgctaaat
     2761 aattcttgag ttgatagaaa gcaaggcttt gtggtcttgc tttttatatg gaaaaatgga
     2821 tgacacgatc atccattctt ttttaattct ttttcaaatg tatttgaaag ggtagtgaaa
     2881 gttagcttct ctaaagtaag tgggtgggta aaggaaagtc ggaaggcatg aagcataagc
     2941 cgacttgtct ttgatttact attatagaga gggtcgccca ggataggaag attatgatgc
     3001 gaaaggtgca cacgaatctg atgggttcgc cctgtcttta gcttgcaacg agccaaggaa
     3061 gtcttgtttg agaattgctt taatctgctt acatgcgttt cagcatattg cccatttttt
     3121 gcatcaacta ttctttttct acgatcatgg cgatcacgtc caattttgtc tctgaaaaca
     3181 agttcttttc tgttgatatt tccatcaact agagcccaat attctctaga aatctctttt
     3241 ttctccaata agcgattgag aatgggcagg ataaaaggat ttttggcaaa gagaactaag
     3301 ccactggttt ccatgtccag acgatgaacg acatagcagg tttggccaac ataggtactg
     3361 acatggttaa gaagggcaat ttcgtttggt tgattaccat gcgttttcat cccctctggt
     3421 ttgtttacaa taatcaagtg ttgatcttga taaacttcct gcactaagtc tgggttgccc
     3481 caagggatcg tcttttggga ataatcttcc tcgtcaaaag tcaactggca aacatctcca
     3541 ggatttacga tttcgttcca gtggacttct tcttgattta tcaaaatatg tttcttgatt
     3601 ctcaaaaaat gacggatttt tctagggatg aggagttgtt cctcaagtaa ttgctttacc
     3661 gtcatttgag gtagagaggc gggtaatgta aatgtgaatt gcatacagat attgtaacaa
     3721 aaaaagccct atttggatag gaaatagcta aattcttgtc ttcctatgat gaagatgata
     3781 aaataaacgc atgaaattag ataaattatt tgagaaattt ctttctcttt ttaaaaaaga
     3841 aacaagtgaa ctagaggact ctgattctac tatcttacgt cgctctcgta gtgatcgaaa
     3901 aaaattagcc caagtaggtc cgattcgaaa attctggcgt cgttatcatc taacaaagat
     3961 tatccttata ctaggtttga gtgcaggatt gctagttgga atctatttgt ttgctgtagc
     4021 caagtcgacc aatgtcaatg atttgcaaaa tgccttgaaa actcggactc ttatttttga
     4081 ccgtgaagaa aaagaggctg gtgccttgtc tggtcaaaag ggaacctatg ttgagctgac
     4141 tgacatcagt aaaaacttgc agaatgctgt tattgcgaca gaagaccgtt ctttctataa
     4201 aaatgacggg attaactatg gccgtttctt cttggctatt gtcactgctg gacgttcagg
     4261 tggtggctct actattaccc aacagctggc taaaaacgcc tatttatcgc aggatcaaac
     4321 tgttgagaga aaagcgaaag aatttttcct tgccttagaa ttaagcaaaa aatatagtaa
     4381 ggagcaaatt ctaaccatgt accttaacaa cgcttatttt ggaaatggtg tgtggggtgt
     4441 agaagatgcg agtaagaaat actttggagt ttctgcatca gaagtgagtc tggatcaagc
     4501 tgcgactctg gcagggatgc tcaaggggcc ggaactgtat aatcccttga attctgtaga
     4561 agattctact aatcggcgcg atactgtctt gcagaatatg gttgcagcag gatatattga
     4621 taaaaaccaa gaaaccgaag ctgctgaagt tgatatgact tcgcaattgc acgataagta
     4681 tgaaggaaaa atctcagatt accgttaccc ctcttatttt gatgcggtgg ttaatgaagc
     4741 tgtttccaag tataatctaa cagaggaaga gattgtcaat aatggctacc gcatttacac
     4801 agagctggac caaaactacc aagcaaatat gcagattgtt tatgaaaaca tatcgctatt
     4861 tccgagggca gaggatggaa cgtttgctca atcaggaagt gtagctctcg aaccgaaaac
     4921 agggggagtt cgtggagttg tcggtcaagt tgctgacaat gataaaactg gattccggaa
     4981 tttcaactat gcaacccaat caaagcgtag tcctggttct acaattaagc ctttagttgt
     5041 ttatacgcca gcagttgaag caggctgggc tttgaataag cagttggata accataccat
     5101 gcagtatgac agctataagg ttgataacta tgcagggatc aaaacgagtc gagaagttcc
     5161 tatgtatcaa gccttggcag aatcgcttaa tctacctgct gttgccactg ttaatgattt
     5221 gggtgtcgac aaggcttttg aggcaggcga aaaattcgga ctcaacatgg aaaaggttga
     5281 ccgtgttctt ggtgtcgcct tgggaagcgg tgttgaaacc aaccctcttc aaatggctca
     5341 agcatacgcc gcctttgcaa atgaaggttt aatgcctgaa gctcatttta ttagtagaat
     5401 tgaaaatgct agtggacaag ttattgcgag tcataaaaat tcacaaaaac gggtgattga
     5461 taagtctgta gctgacaaga tgaccagtat gatgttgggg actttcacca acggtaccgg
     5521 tattagttca tcgcctgcag actatattat ggcagggaaa actggaacaa ctgaagcagt
     5581 ttttaatccg gagtacacaa gtgaccagtg ggtaattggt tatactccgg atgtagtgat
     5641 tagccactgg cttggctttc cgaccactga tgaaaaccac tatctagctg gctctacttc
     5701 aaacggtgca gctcatgtct ttagaaacat tgccaatacc attttacctt atacgtcagg
     5761 aagtaccttt acggttgaaa atgcttataa gcaaaatgga attgcaccag ccaatacaaa
     5821 aagacaagta caaaccaatg ataatagcca gacagatgat aatttgtctg atattcgagg
     5881 gcgtgcgcaa agtctagtag atgaggctag ccgggctatc tcagatgcga agattaagga
     5941 aaaggctcaa acaatatggg attcgatagt caatctattt cgctaagatg cttgtcaaag
     6001 cctagctttc ttgttataat ggataagatg gaggcgttat ggcactaaaa aaagcaagcc
     6061 tagcttgtgc ggtttgtggt tcgagaaact attcaatcaa gatcagcgga aaccccaagc
     6121 ctacacgact agaagtaaat aaattttgta agcattgtgg caagtacact acacatagag
     6181 aaacgagata ggagagagcg atgcgtttta ttggagatat ttttagactt cttaaagaca
     6241 caacgtggcc aactcgcaag gaaagctgga gagattttcg ttctatcatg gaatacacag
     6301 ctttctttgt agtaattatt tacatttttg accagttgat tgtttcaggt ttgattcgat
     6361 ttattaacat tttttagaag attagtggag ttaattacac tagaaatctt ctatttatga
     6421 aaggaaatat catggatagt tttgataaag gatggtttgt tttacaaact tattctggtt
     6481 atgaaaataa ggtgaaagaa aatctattac aacgtgcaca aacctacaat atgttggata
     6541 atattctacg cgttgaaatt ccaacacaaa cagtgcaagt tgaaaaaaat ggaaagagaa
     6601 aagaagtaga agaaaatcgc tttccaggtt atgttcttgt agaaatggtc atgacagatg
     6661 aagcttggtt tgttgttcga aacacaccaa atgttacagg atttgtcgga tcacacggga
     6721 acagatcaaa accaactcca ttattggaac aagaaattcg tgacattttg gtatctatgg
     6781 gacaaactgt tcaagaattt gatttcgatg ttgagattgg tcaaactgta cgtattattg
     6841 atggtgcttt tgcagactac actggtaaga ttacagaaat tgataataac aaagtgaaaa
     6901 tgattatctc tatgtttggt aatgacacag ttgcagaagt aaacctaaac caaatcgcag
     6961 aat
//
LOCUS       DBEJAU010000074         6657 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC323 isolate 683620
            SAMN38261939-rid24807223.denovo.074, whole genome shotgun sequence.
ACCESSION   DBEJAU010000074 DBEJAU010000000
VERSION     DBEJAU010000074.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261939
            Sequence Read Archive: SRR26833919
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 6657)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6657)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576303.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576303.1
            Genome Coverage       :: 154x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/19/2025 01:05:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,121
            CDSs (total)                      :: 2,078
            Genes (coding)                    :: 1,943
            CDSs (with protein)               :: 1,943
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 36
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 72 of 135
            Pseudo Genes (incomplete)         :: 63 of 135
            Pseudo Genes (internal stop)      :: 51 of 135
            Pseudo Genes (multiple problems)  :: 46 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6657
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261939-rid24807223.denovo.074"
                     /strain="GPSC323"
                     /isolate="683620"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            66..230
                     /locus_tag="ACL29Z_001949"
     CDS             66..230
                     /locus_tag="ACL29Z_001949"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000508323.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YczI family protein"
                     /protein_id="HGR0070203.1"
                     /translation="MGFYLMVASMLLGLLALKIGFSQFKEKKDKFLSILTSLAGTALV
                     LVAVWLGWPK"
     gene            309..1037
                     /gene="yaaA"
                     /locus_tag="ACL29Z_001950"
     CDS             309..1037
                     /gene="yaaA"
                     /locus_tag="ACL29Z_001950"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000697769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peroxide stress protein YaaA"
                     /protein_id="HGR0070204.1"
                     /translation="MKILIPTAKEMNTDLPSIEAIPLKPESQAVLDALALYSASQLES
                     FYKVSAEKAAEEFQNIQALKRQTAQHYPALKLFDGLMYRNIKRDKLTEAEQDYLENHV
                     FITSALYGVVPALSPMAPHRLDFLMKLKVAGKTLKSHWKAVYDEALKKEEVIFSLLSS
                     EFETVFSKEIRAKMVTFKFMEDRGGQLKIHSTISKKARGAFLTALIENQVQTVGEARR
                     LNFAGFVYREDLSQPQGLVFVKEV"
     gene            complement(1088..2572)
                     /locus_tag="ACL29Z_001951"
     CDS             complement(1088..2572)
                     /locus_tag="ACL29Z_001951"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003096885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M protein trans-acting positive regulator PRD
                     domain-containing protein"
                     /protein_id="HGR0070205.1"
                     /translation="MRNLLSTKVQRQLRLMETLIQNRNWMKLHELAEKLGCTERILKS
                     DLNELRIAFPSINIQSSVNGIMIDLEVNTSVEDIYQYFLANSQSFQLLEYMFFNEGLP
                     IYRTIENLYFSSANLYRLGRNITKVLSSQFQIELSFTPSEIRGNEIDIRYFFAQYFSE
                     RYYFLDWPFPDLPEEDLTEFADFFYKITNYPMRFSIYRMYKLMIAISIHRVKNGHFID
                     LPNHFYKEYYPLLKSIPNFQETLAYFSKHFGLEMTPDTIAQIFISFLQNDIFLDPQEF
                     FNSLEDNSQARYSYQLLSQILELLSKQYKITFTNHDELIWHLHNTAFFERQEIFSTPI
                     LFEQKALTIKKFEVYFPDFMGSARQELAQYRQAIGQHDHPEQLEHLMYTILTHAENLS
                     TQLLENRPPIKVLIISNFDHAISLTFVDMLSYYCNNRFTFDIWDELKTSPEILNQTDY
                     DIIVSNFYIPGITKKFICRNHLSIMNLVNHLNTLSNEIHLSNTL"
     gene            2788..>6657
                     /locus_tag="ACL29Z_001952"
     CDS             2788..>6657
                     /locus_tag="ACL29Z_001952"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="G5 domain-containing protein"
                     /protein_id="HGR0070206.1"
                     /translation="MKHSHKKSFDWYSMQQRYSIRKYYFGAVSVLLGTALVLGAASSV
                     QTVQAEENKQETTNSISVGRGEAATKPAEVSASNKEKTYAAPTVANPVETTPVKTGEV
                     TKPAEKVEEAKDKKEEVTHQDAIDKSKLLTALSRAKKLESKLYTEASAANLQTSIQAG
                     QSLLGKADASEAELSAAESSIQSSIIGLELRSKSNKGTVSETPVAKKANIVEAKEETN
                     PAATTDRSAVDSAVLPTSTAAKVETTSAPASINEILKPGLSLSDARQNPAIRKEDLDK
                     GHSGFRASSNPANPIVSGSGNTVAFSDISQAGRSYSFRGYGNSRGGNSIHYDVTTVRQ
                     GNKLNFTIEYSGPGEFVNNNFILDKGDGFGNPSNATITTPRLREQSKPVSQGGNFVSH
                     SGYSMTSATSTSERQTIRFSLPINNPNGDLSVRLKPVTFNVNQGGGSAATGNDPYSNS
                     NYYFREKPLLLDANPYGGTHSKPITEDIDFQTVYLPTSKLAEGETRLVREGEKGQRQI
                     TYKVHRFGNETVLGLPISNRVTKEAKPRIMQIGVAKELIDTVKPRVDQNKVGDTNNLT
                     FYLDNDGNGVYTEGVDELVQKIAIKDGAKGEKGDQGERGLTGAQGAKGEKGDRGERGL
                     TGAQGAKGEKGDRGERGLTGAQGAKGEKGDRGEHGLTGAQGAKGEKGAQGERGLTGAQ
                     GAKGEKGDQGERGLTGAQGAKGEKGDKGEQGPKGEDGKTPTVKVTDGQDGTHTITIND
                     GKGGITTTVVRDGFDGASPLVSTHRNEADKTTTVIFYYDLNDNNQFDEGDTKLKEVVI
                     ADGKQGPKGDKGDNGKDGFTPEVTVTDNNNGTHTITITQPDNRPSLTTIVKNGEDGKT
                     PKVKAERDDAKKQTTLTFYIDKDGDGSYTAGKDELVQTTVVKDGQDGAAGASGRDGKE
                     VLNGKVDPTTEGKDGDTFVNTQTGDVFVKKGNTWEPAGNIKGPKGDKGADGAKGEKGA
                     QGERGLTGAQGVKGEKGDQGERGLTGSKGEKGDQGERGLTGAQGDKGEQGLQGRDGAQ
                     GPKGADGQRGPAGPQGPKGEQGNPGTPGKDGKSLIAVKNGTETKVYVEDPARPGQPLN
                     PNQPLATITDGRNGTNGQSPTITATRSVQNGKNGVLVTITPVEGRPQTTFVEDGQKGA
                     DGKTPTVTITEGQNGTHTLTVHNPGSPDVTTTIRDGATGQAGRDGKDVLNGKVNPQPN
                     QGKNGDKYINTETGDVYVKNNGNWDKEGNIKGPKGDKGADGAKGEKGDQGERGLTGAQ
                     GAKGADGAVGRDGRDGKDVLNGKANPEA"
BASE COUNT         2374 a         1121 c         1479 g         1683 t
ORIGIN      
        1 aaaaaggttt atttaagaaa tatatgttat aataaggtaa attaagccta atggaggaca
       61 aagaaatggg tttttatttg atggttgctt caatgctact cggactgctc gctttgaaga
      121 taggtttttc tcagttcaag gagaaaaaag ataaattctt atctatctta acaagtttag
      181 ctggcacagc ccttgttctc gtggctgtct ggttaggatg gcccaaataa atagaaaaac
      241 ctcggtcaaa ccgaggtttt tcaaatgaat ttcttggttg tggctaaaaa atatgctaca
      301 ctatcaatat gaaaatttta atcccaacag caaaagaaat gaacacagac ttgccaagta
      361 tcgaggcaat tcctttaaaa ccagaaagtc aggccgtgct tgatgccttg gctctctatt
      421 ctgccagtca attggagagt ttctacaagg tatcagctga gaaagcggcg gaagaatttc
      481 aaaatatcca agctttgaaa aggcaaactg ctcaacacta tccagccttg aaactttttg
      541 atgggcttat gtaccgcaac attaagagag ataagctgac cgaggcggaa caagattatc
      601 ttgaaaatca tgtcttcatt acctcggctt tgtacggtgt tgttccagcc ttgtcaccca
      661 tggctcctca ccgtttggat tttttgatga aattaaaagt cgctggtaag actttgaaga
      721 gccattggaa ggcagtctat gatgaagctc tgaagaagga agaagtgatt ttctctctct
      781 tgtcatcaga gtttgagact gtattttcta aggaaatcag agcaaagatg gtgaccttca
      841 aattcatgga ggatagaggc ggtcagctga agattcactc aactatctcc aagaaagcgc
      901 gcggggcctt tctaacagct ttaatagaaa atcaagtaca aactgtgggg gaagcacgtc
      961 gcttgaactt tgctggattt gtttaccgag aagatttgtc acaaccacag ggattggttt
     1021 ttgtaaagga agtatagaaa tcagataaga gaaaagtcag cacgattatg ctgacttttt
     1081 tgataactta taaagtattg gacaaatgaa tctcatttga taaggtgtta agatgattaa
     1141 ccaaattcat gattgacaga tgatttcggc aaataaactt cttggtaatc cctggaatat
     1201 agaaattaga cacgatgata tcgtaatctg tctgatttaa aatctcagga cttgttttta
     1261 attcatccca aatatcgaag gtaaagcggt tattacagta ataggaaagc atatcaacaa
     1321 aggtaaggga tatagcatgg tcaaagttac tgataatcaa aaccttgata ggtggtcgat
     1381 tttctaacaa ctgagtagag aggttttcag catgggttaa gatggtgtac atcaagtgtt
     1441 ccaactgttc aggatggtca tgctgtccaa ttgcctgacg gtattgagcc agttcttgac
     1501 gcgcacttcc cataaagtct gggaagtaaa cttcaaattt tttaatcgtc aatgcttttt
     1561 gttcaaataa gattggggta gaaaagattt cctgtctttc aaagaaagca gtgttgtgta
     1621 aatgccaaat cagctcatcg tggttagtaa aagtaatctt atattgtttt gataggagtt
     1681 ctaatatttg actaagtaat tgataagagt atcttgcttg actgttatct tctaaagagt
     1741 tgaagaattc ttgaggatct aggaaaatat cattctgaag aaaagaaata aaaatttgag
     1801 cgattgtatc tggagtcatt tcaagcccaa aatgtttaga gaaataagca agtgtctcct
     1861 ggaaatttgg aatgctcttt aaaagaggat aatattcttt gtaaaagtgg ttggggaggt
     1921 caatgaagtg accattttta accctgtgga tactgatagc tatcatcagt ttgtacattc
     1981 tataaattga aaatcgcatt ggataattcg tgattttata gaagaagtca gcaaactctg
     2041 ttaaatcttc ctcaggaagg tcaggaaaag gccaatctag gaaataatag cgctcagaaa
     2101 agtattgggc aaaaaagtaa cgaatatcga tctcatttcc acgtatctcg gatggagtaa
     2161 aagataattc aatttgaaac tgagatgaaa gaacctttgt aatatttctg cccagtcgat
     2221 agaggttggc actactaaag taaagatttt ctattgttcg ataaataggt agcccctcat
     2281 tgaagaacat atactctagt aattgaaaag attgagaatt agcaagaaaa tattgataaa
     2341 tatcttctac actagtgtta acttctaaat ctatcatgat tccgttaaca gaagattgga
     2401 tgttaataga tggaaaggca atacgtaatt catttaaatc actttttaag attcgttctg
     2461 tacatcctaa tttttcggct agttcatgta atttcatcca attacgattc tgaattaggg
     2521 tttccattaa gcgtaattgt ctttgaactt ttgtggataa aaggtttctc atacgggtat
     2581 ttcctccata attcattata tctttttttg tctaagtagt ataaaaaaat tagagcaaga
     2641 aaattgtcgt tagtaatcgg aaaaattaga ataatataag tggcttttaa gtgcaaaaac
     2701 agaatatatt aattgttcag aaaatattga ttaatgcctc aaatagttgt acattgtaaa
     2761 ctataaaata ctatctagga gtttaaaatg aaacattcac ataaaaaatc atttgactgg
     2821 tatagcatgc aacaacgtta ttctattcgt aagtattact ttggtgcagt tagtgtcttg
     2881 ctcggtaccg ctttggtatt aggtgcagca tctagtgtcc aaacagtaca agcggaagaa
     2941 aacaaacaag aaactaccaa tagtatttct gttggtaggg gagaagcagc tactaaacca
     3001 gcagaggttt ctgcgtctaa taaagagaaa acctatgcag ctccaactgt agctaatcca
     3061 gtagaaacga ctccagttaa aactggagaa gttactaaac cagcagaaaa agttgaagaa
     3121 gcaaaagaca aaaaagagga agtaacgcat caagatgcta ttgacaagtc aaaattgtta
     3181 acggctcttt cgcgtgctaa aaagttagaa agcaagttat atacagaagc aagtgctgct
     3241 aacttgcaaa caagtatcca agctggtcaa agcttgcttg ggaaagcaga tgcatctgaa
     3301 gctgaattat cagcagcaga gtcatctatt caatcatcta ttattggtct agaacttcgt
     3361 tctaaatcta acaaaggaac tgtatcagaa actcctgtag cgaagaaagc taatatagtt
     3421 gaagcgaagg aagagactaa tccagctgca acaactgatc gttcagctgt tgatagtgct
     3481 gttttgccaa ctagcacagc tgccaaagta gaaacaactt cagctccagc atctattaat
     3541 gaaatcttga aaccaggttt gagcctttct gatgctcgtc aaaatccagc tatccgtaag
     3601 gaagacttgg ataaagggca tagtggtttt agagcttcta gcaatccagc caacccaatt
     3661 gtctcaggtt ctggtaacac agttgcgttt tcagacatta gtcaagctgg tcgtagttat
     3721 agttttcgtg gctacgggaa ctcacgtggt ggtaattcaa ttcattacga tgtaacaaca
     3781 gtacgtcaag gtaataaatt gaatttcaca atcgaatatt ctggtccggg cgaatttgtt
     3841 aataataact ttatcttgga taaaggggat ggatttggaa atccttcaaa tgcaactatc
     3901 acaactccaa ggttaagaga gcaatcaaaa cctgttagtc agggtggcaa cttcgtatct
     3961 cactcaggat acagtatgac ttctgctact tcaacgagtg agagacaaac tatcagattt
     4021 agcttgccaa tcaataatcc aaatggtgac ttatctgttc gtttgaaacc tgttactttt
     4081 aacgtaaacc aaggtggagg tagtgcagct actggcaatg acccatatag taactctaac
     4141 tattacttca gagaaaaacc actcctcttg gatgcaaacc cttatggcgg tactcatagc
     4201 aagcctataa cagaagacat tgacttccaa actgtctatc ttccaactag taagttagca
     4261 gaaggtgaaa ctagattagt tcgagaaggt gaaaaaggac aacgtcaaat tacctataaa
     4321 gttcatcgat ttggtaacga aacagtctta ggattgccaa ttagtaatag agttactaaa
     4381 gaagctaagc cacgtattat gcaaattggt gtggctaaag agctaatcga tacagtaaaa
     4441 ccacgtgttg atcaaaataa agttggtgat acaaataacc tcactttcta tcttgataac
     4501 gatggcaacg gtgtttatac tgaaggtgta gacgaacttg ttcaaaaaat tgctattaaa
     4561 gatggagcta aaggtgaaaa aggagaccaa ggtgaacgcg gtctaaccgg agcacaaggt
     4621 gctaaaggtg aaaaaggaga ccgaggcgaa cgcggtctaa ctggagctca aggagctaaa
     4681 ggtgaaaaag gagaccgagg tgaacgcggt ctaactggag ctcaaggagc taaaggtgaa
     4741 aaaggagacc gaggcgaaca cggtctaact ggagctcaag gagctaaagg tgaaaaagga
     4801 gcccaaggtg aacgcggtct aaccggagca caaggtgcta aaggtgaaaa aggggaccaa
     4861 ggtgaacgcg gtctaaccgg agcacaaggt gccaaaggtg aaaaagggga caaaggtgaa
     4921 caaggaccaa aaggagaaga tgggaaaacc ccaacagtta aagtaactga tggtcaagat
     4981 ggaacgcata caattacaat taacgatggt aaaggtggta taactactac agtagtaaga
     5041 gatggatttg atggtgcaag ccctcttgtt tctactcata gaaatgaagc agataaaaca
     5101 acaactgtta ttttctatta tgatctaaat gataataatc aatttgatga aggagataca
     5161 aaacttaaag aagttgttat cgcagatgga aaacaaggac caaaaggtga caaaggtgat
     5221 aacggaaaag atggattcac accagaagta acagttacag ataacaataa cggaacacac
     5281 accatcacaa tcacacaacc agacaacaga ccatcattaa caacaatcgt taaaaacggt
     5341 gaagatggaa aaacaccaaa agtcaaagca gaacgagatg atgcgaagaa acaaacaaca
     5401 ttaacattct acattgacaa agatggagat ggaagttaca cagcaggaaa agacgagtta
     5461 gttcaaacaa cagtagttaa agacggacaa gacggagctg caggagcatc tggacgtgat
     5521 ggaaaagaag tattaaacgg aaaagtagac ccaacaacag aaggtaaaga tggagacaca
     5581 ttcgtaaata cacaaacagg agatgtattc gttaagaaag gtaacacttg ggaaccagca
     5641 ggaaacatca aaggaccgaa aggtgacaaa ggtgcagatg gtgccaaggg tgaaaaagga
     5701 gcccaaggag aacgcggcct gactggagcg caaggtgtta agggtgaaaa gggagatcag
     5761 ggtgaacgcg gtctaactgg atctaaaggt gaaaaaggag accaaggtga acgcggttta
     5821 actggagcgc aaggtgacaa aggtgaacaa ggtcttcaag gtcgtgatgg agctcaagga
     5881 ccaaaaggag cagatggaca aagaggacca gcgggaccac aaggaccaaa aggagaacaa
     5941 ggtaatccag gaactccagg taaagatgga aaatctctaa ttgctgttaa aaatggaact
     6001 gaaacaaaag tctatgtaga ggatccggct agaccaggac aaccacttaa tccaaaccaa
     6061 ccattagcaa ctatcactga tggacgaaac ggtactaatg gacaatcacc aacaattaca
     6121 gcgacacgaa gtgtgcaaaa tggcaaaaat ggtgtattag taacaattac accagtagaa
     6181 ggtcgtccac aaacaacatt tgtagaggat ggacaaaagg gtgctgatgg gaaaactcca
     6241 acagtaacaa taactgaggg gcaaaacggc acacatacat taacggttca taatccagga
     6301 agtccagatg tgacaactac gatccgtgat ggagctacag gacaagcagg tcgtgatggt
     6361 aaagatgtat taaacggaaa agtaaatcca caaccaaacc aaggtaaaaa tggagataaa
     6421 tatattaata ccgaaaccgg tgatgtctat gttaaaaaca atggaaactg ggataaagaa
     6481 ggcaacatca aaggccctaa aggtgacaaa ggtgcagatg gtgctaaagg cgaaaaagga
     6541 gaccaaggcg aacgcggcct aactggagcg caaggagcta aaggtgcgga tggcgcagta
     6601 ggtcgtgatg gacgtgacgg taaagacgtg ttgaacggca aagctaaccc agaagca
//
LOCUS       DBEJAU010000075         6537 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC323 isolate 683620
            SAMN38261939-rid24807223.denovo.075, whole genome shotgun sequence.
ACCESSION   DBEJAU010000075 DBEJAU010000000
VERSION     DBEJAU010000075.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261939
            Sequence Read Archive: SRR26833919
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 6537)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6537)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576303.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576303.1
            Genome Coverage       :: 154x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/19/2025 01:05:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,121
            CDSs (total)                      :: 2,078
            Genes (coding)                    :: 1,943
            CDSs (with protein)               :: 1,943
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 36
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 72 of 135
            Pseudo Genes (incomplete)         :: 63 of 135
            Pseudo Genes (internal stop)      :: 51 of 135
            Pseudo Genes (multiple problems)  :: 46 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6537
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261939-rid24807223.denovo.075"
                     /strain="GPSC323"
                     /isolate="683620"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            complement(141..213)
                     /locus_tag="ACL29Z_001953"
     tRNA            complement(141..213)
                     /locus_tag="ACL29Z_001953"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(178..180),aa:Thr,seq:ggt)
     gene            complement(313..822)
                     /locus_tag="ACL29Z_001954"
     CDS             complement(313..822)
                     /locus_tag="ACL29Z_001954"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262434.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="QueT transporter family protein"
                     /protein_id="HGR0070207.1"
                     /translation="MKKLTIRDVADIAIVAAIYVVLTVTPPLNAISYGAYQFRISEMM
                     NFMAFYNPKYIIGVTIGCMIANFFSFGLLDVFVGGGSTLVFLSLGVWLFAKYSKDYLF
                     NGLIRKDHFFFSILFSISMFTIAAELNIVAELPFFLTWFTTGIGEFASLIIGAIIIGK
                     IGRRIDLSK"
     regulatory      complement(820..916)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF01054"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="PreQ1 riboswitch class II; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="preQ1"
                     /db_xref="RFAM:RF01054"
     gene            945..1376
                     /locus_tag="ACL29Z_001955"
     CDS             945..1376
                     /locus_tag="ACL29Z_001955"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000743000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GtrA family protein"
                     /protein_id="HGR0070208.1"
                     /translation="MKKPIQKFFNNEILAYLFFGLATTLVSILSRLVIYQLSHQELLA
                     TALANIIGILFAFITNDTIVFKQKKKNRLIRLVKFSLARLSTFLLDLFLTFLFVTQFP
                     HIIGQFVTENIDKINAIETIIAQIFIIIINYILSKVYIFRK"
     gene            1458..1835
                     /gene="mscL"
                     /locus_tag="ACL29Z_001956"
     CDS             1458..1835
                     /gene="mscL"
                     /locus_tag="ACL29Z_001956"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001855364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008381 - mechanosensitive monoatomic ion
                     channel activity [Evidence IEA];
                     GO_process: GO:0006810 - transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="large conductance mechanosensitive channel
                     protein MscL"
                     /protein_id="HGR0070209.1"
                     /translation="MLKNLKSFLLRGNVIDLAVGVVIASAFGAIVTSLVNDIITPLIL
                     NPALKAAKVERIAQLSWHGVGYGNFLSAIINFIFVGTALFFIIKGIEKAQKLTGIKEE
                     KTAEKKPTELEVLQEIKALLEKK"
     gene            complement(1877..2971)
                     /gene="hemH"
                     /locus_tag="ACL29Z_001957"
     CDS             complement(1877..2971)
                     /gene="hemH"
                     /locus_tag="ACL29Z_001957"
                     /EC_number="4.98.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004325 - ferrochelatase activity
                     [Evidence IEA];
                     GO_process: GO:0006779 - porphyrin-containing compound
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ferrochelatase"
                     /protein_id="HGR0070210.1"
                     /translation="MKKAILMMTFGSPEEITFEGVADFFTNIRRGVRPQDHEIQTLYD
                     NYVRIGGTPLQKITRQEVALVEARLGNEYSVYFANKFSSPFIPDVIGQMEADGIEQCI
                     CLILEPHYSFYSVMGYEKFLESKQIQFLVIKDWYQEEALLNYWADEIAKILKEEAKQD
                     SFKVIFSAHSVPIFALDFGDPYIDQIFENSKLVAEKLGLSSKQYTNTWQSESDIGIPW
                     IKPDVLEYLREQTEHPDHYIFVPISFISEHIEVLFDNDVECYDLCQEFGVNYHRPPMP
                     NTDSRLIDALVNTIRINENQEFKEFLPEEETFDELVPSDETKNILAESEDLQMPEFVK
                     KLIEKKGRENVKMPYLIKKMLEKAGKLPKE"
     gene            3126..4346
                     /gene="pepT"
                     /locus_tag="ACL29Z_001958"
     CDS             3126..4346
                     /gene="pepT"
                     /locus_tag="ACL29Z_001958"
                     /EC_number="3.4.11.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000222043.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_function: GO:0045148 - tripeptide aminopeptidase
                     activity [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase T"
                     /protein_id="HGR0070211.1"
                     /translation="MTYPNLLDRFLTYVKVNTRSDEHSTTTPSTQSQVDFATNVLIPE
                     MKRVGLQNVYYLPNGFAIGTLPANDPSLTRKIGFISHMDTADFNAEGVNPQVIENYDG
                     GVIELGNSGFKLDPADFKSLEKYPGQTLITTDGTSLLGADDKSGIAEIMTAIEYLTAH
                     PEIKHCEIRVGFGPDEEIGVGANKFDAEDFDVDFAYTVDGGPLGELQYETFSAAGAEL
                     HFQGRNVHPGTAKGQMVNALQLAIDFHNQLPENDRPELTEGYQGFYHLMDVTGSVEEA
                     RASYIIRDFEKDAFEARKASMQSIADKMNEELGSNRVTLNLTDQYYNMKEVIEKDMTP
                     ITIAKAVMEDLGITPIIEPIRGGTDGSKISFMGIPTPNIFAGGENMHGRFEYVSLQTM
                     ERAVDTIIGIVRSL"
     gene            complement(4389..5042)
                     /locus_tag="ACL29Z_001959"
                     /pseudo
     CDS             complement(4389..5042)
                     /locus_tag="ACL29Z_001959"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000672614.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="HIT family hydrolase"
     gene            5040..5204
                     /locus_tag="ACL29Z_001960"
                     /pseudo
     CDS             5040..5204
                     /locus_tag="ACL29Z_001960"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015057566.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS110 family transposase"
     gene            complement(5475..6487)
                     /locus_tag="ACL29Z_001961"
                     /pseudo
     CDS             complement(5475..6487)
                     /locus_tag="ACL29Z_001961"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000669441.1,RefSeq:WP_007521835.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal-type histidine triad protein"
BASE COUNT         1951 a         1275 c         1158 g         2153 t
ORIGIN      
        1 gcggctagtt tcctagttta ctctttgatt ttcattgagt attagtttta tttacacagg
       61 tgcataagaa atatattgga aaaattgggg gcagacataa caaaaaccct tgtaaatcaa
      121 gggcttttct gtctatttaa tgctaattgc cgggattgaa ccggcgacct catccttacc
      181 atggatgcgc tctgccaact gagctaaatc agcttactta agaagtatac tataatcaga
      241 aaaacttgtc aagtttcctt agaaattttc cataggaaaa agccaggtaa gaactaccta
      301 gcttatcttc ttctatttac ttaaatcaat tcgacgacca attttaccaa taataatcgc
      361 tccaataatc aatgaagcaa attcaccgat tcctgttgta aaccaagtaa ggaagaatgg
      421 taattctgct acaatattta actctgcagc gatagtaaac atggaaattg aaaagaggat
      481 tgaaaagaag aaatgatctt ttcgaatcaa tccgttaaag aggtaatcct tgctatattt
      541 tgcaaaaagc caaacaccta aactgaggaa tactaaggtt gaaccaccac caacaaagac
      601 atctagcagt ccgaagctaa agaaattagc aatcatacaa ccgatggtaa ctccgatgat
      661 gtacttagga ttgtaaaaag ccataaagtt catcatttct gaaatacgaa actgataagc
      721 accatagctg atggcattta ggggcggtgt gacagtcaaa acgacgtaga tagcagcgac
      781 gattgcaata tctgcaacat cacgaatagt taattttttc atcttttctc ctttggcggt
      841 tatccgcgtg taatatgctt ggtgaaagaa gctaagcacc aagggttgat tcattcaacc
      901 ttactagtat agcacaatag cctgctttat gctatactta aagcatgaaa aaacctattc
      961 aaaaattttt taacaatgaa atcttagcct atctcttttt tggccttgcg acaactctag
     1021 tttcgattct ctcacgacta gtcatttatc aactaagtca tcaggaactc cttgctacgg
     1081 ccttggcaaa tattatcggt atcttatttg cctttatcac aaatgatacg attgtattta
     1141 agcaaaaaaa gaaaaataga cttatccgtt tagtgaaatt ttctcttgct cgcctttcta
     1201 cttttctgtt agacttgttt ttaacttttc tctttgtaac ccaatttcct cacatcatag
     1261 ggcaattcgt aactgaaaac attgataaga taaatgctat tgaaacaata attgcacaaa
     1321 tattcattat tatcatcaat tatatcttga gcaaggtcta tatttttaga aaataatgct
     1381 ccatttatga gccttttaat tgccttctat aatgatttag gatacaatga aacacgaaac
     1441 attgaaagga aaacagtatg ttaaaaaatc taaaatcgtt cttgcttcga ggaaatgtta
     1501 ttgaccttgc tgtcggtgtt gtcattgcct ctgcttttgg tgctatcgtt acttcacttg
     1561 taaacgacat tatcactcct cttattttaa atcccgcttt gaaagctgct aaagttgaac
     1621 gtatcgctca actttcttgg catggagtcg gctatggtaa cttcttaagt gctattatca
     1681 attttatctt tgtgggtacc gccctcttct ttattatcaa gggcattgaa aaagcacaga
     1741 aactgactgg cataaaggaa gaaaaaactg ccgaaaaaaa accaaccgaa ttggaagtcc
     1801 ttcaagaaat aaaagctctc cttgagaaaa aataatcgat taaaaggatc tagcgcaaag
     1861 ctaaatcctt ttttctttac tctttgggta acttgcctgc tttttcaagc atttttttga
     1921 taagataagg catcttaaca ttctcccgcc cttttttctc aatcagtttt ttcacaaatt
     1981 ctggcatttg taaatcttca gattcagcca aaatgttttt cgtctcgtct gaaggaacta
     2041 actcatcaaa ggtctcttct tctgggagaa attccttaaa ctcttgattt tcattgattc
     2101 taattgtatt gaccaaagca tcaatcaaac gagaatctgt atttggcatt ggtggacgat
     2161 ggtagtttac cccaaattcc tgacataagt cataacattc cacatcattg tcaaacaaga
     2221 cctcaatatg ctcactgatg aaactaatag gtacaaaaat ataatggtct ggatgttctg
     2281 tctgttctct gagatactcc aaaacatctg gtttaatcca tggaatacca atatcactct
     2341 cactctgcca agtgttggta tattgttttg aactcaagcc cagtttttca gcgactagct
     2401 tgctattttc gaaaatttgg tctatataag gatcaccaaa gtccaaggca aaaatgggca
     2461 cactatgggc tgaaaagatg actttaaagc tgtcttgctt tgcttcttct tttaaaatct
     2521 tagcaatttc atctgcccaa tagtttaaga gcgcttcttc ctgataccag tccttaatga
     2581 ccaaaaattg aatttgtttg ctttctaaaa atttttcata gcccatgaca gagtagaaag
     2641 aataatgggg ctccaaaatc aagcaaatac actgttcaat tccgtctgct tccatttgac
     2701 cgatcacatc tggaataaag ggactggaaa acttattagc aaagtagaca ctgtattcat
     2761 tccccagcct agcttctacc aaggcaacct cttgacgggt aattttttgc agaggcgtgc
     2821 ctccaattcg tacataatta tcatagagag tctgaatctc gtggtcttgg ggtctcaccc
     2881 cacgacgaat atttgtgaaa aaatcagcta caccttcaaa ggtaatctct tctggtgaac
     2941 cgaaggtcat cattaaaatt gcttttttca tgactgcttc cttgtgatgt ttttatcaag
     3001 tttattttat cattaattca tcgataagta aacgctaaca tagggacatt ctcaatcttc
     3061 tgtcttttgt ttttctcttc tttctatgat acaatggaaa aaataaattc aaaaggagtt
     3121 tttttatgac ttatccaaat ctcttggacc gcttcttaac ctacgttaag gtcaacacgc
     3181 gctctgatga acactctact actactccaa gtacacagag tcaggttgac ttcgcaacaa
     3241 atgtcctaat tcctgaaatg aaacgtgttg gactgcaaaa tgtttactat ctaccgaatg
     3301 gttttgctat tggaaccttg ccagccaacg atccgtcttt aacacgtaag attggtttta
     3361 tatcgcacat ggatactgct gattttaatg ctgaaggagt caatccacag gtaattgaaa
     3421 actacgatgg tggtgtgatt gaactaggga attctggttt caaactcgac ccagctgact
     3481 tcaagagtct tgaaaaatat ccaggacaaa cgctcatcac aacagatgga acaagcttgc
     3541 taggtgctga tgacaaatca ggaattgctg aaattatgac agccattgaa tatctaactg
     3601 ctcatcctga aattaagcac tgtgagattc gtgttggttt tggtccagat gaagaaatcg
     3661 gtgttggtgc caataaattt gatgcagaag attttgatgt ggattttgcc tacactgttg
     3721 atggtggtcc actaggtgaa cttcagtacg agactttctc agccgctggt gctgaattgc
     3781 atttccaagg ccgtaatgtc caccctggta ctgccaaagg gcagatggtc aatgcccttc
     3841 agctagcaat tgattttcat aatcaacttc cagaaaatga ccgacctgag ttaactgaag
     3901 gttaccaagg tttttaccat ctaatggatg tgacaggtag tgttgaggag gcgcgtgcaa
     3961 gctacatcat tcgtgatttt gaaaaagatg cctttgaagc gcgtaaagca tccatgcaat
     4021 ctatcgctga taagatgaat gaagaacttg ggagcaaccg tgtcactctc aacttgacag
     4081 accagtacta caatatgaaa gaagtcattg aaaaagatat gactccaatt accattgcta
     4141 aagccgttat ggaagatcta ggtatcacgc ctattatcga accaatccga ggtggaacag
     4201 acggctctaa gatttccttt atgggaatcc caactccgaa tatctttgca ggtggcgaaa
     4261 atatgcacgg acgttttgaa tacgttagcc ttcagactat ggaacgtgca gttgatacca
     4321 tcattggcat cgtacgtagc ttataaaagc taaaaagacg aggtagctca gctacttcgc
     4381 ctttcttttt attctactgg tttttcttga tttccagtag ttgtagaaga ttctgttgtt
     4441 ttattttctg aagttgattc agcaggttta gaatctcttg tattgcttgg tttgttttcg
     4501 tcgctagcag tttcaatgtt agattctgca gttgcgtttg gttggttctc agcactggtg
     4561 ttatcaccat ttgcttcagc atttcttgct ggacttgttt cttcacttgc gctagctttt
     4621 gactggattt gatgattcaa aactagaata gcttttgtcg attcaagtaa agctgttttg
     4681 tctttactct tagcagaaag ttgatctaat aatgcatcca ccttatcaaa gtccgcatca
     4741 gatccattat tactttctaa ataagagtga agcgacatga gaatatcgta gagtttttga
     4801 tagagtacaa gtgtctgagg atcttgctca gcattttcct tttcttgttg aagggcgcta
     4861 gcgatacgag tcaaaacatc ttttacctga ctgtttactt catccaagtc tgcatcagcc
     4921 ttgtttgtgg cagcttttag attttctact tcttctgcca aggattgtct gattccttct
     4981 tcatggattt gttccaagag ttgatttgcc ttgttcaaaa gactttctac ttcttccttg
     5041 ctatctgtcg cagattattg gttgctatct accatgtact cctaaaacag gagagttata
     5101 atccaagatt acaaggcctt acagaaataa gaaatccaga taagacaatg ttcgtccaag
     5161 acgctattcg cttcgcacag cagcacggat tcaatatgct ttaattttaa agtttaggtg
     5221 tcaagacctc tttttagtgt gcccaaaatt tagagaagta atcaatcaac taacttttat
     5281 ttttttcaaa ctttcagtaa actgacctaa agctaactca atctgtcttt gtagatgctt
     5341 ctgctatcag ctagaagttg atctactttt gccaagactg ccttctcatc aaaagttcca
     5401 ggttgatagt tggattgcag ggatggaatc ttgtttttca aagccgcttc atatccctta
     5461 gtttgaacct tgatgtagtg attgtggtcg ccatgaggaa tcacaaaacc ttctgaatct
     5521 tcacttataa ttcgattggc atcaaaaacc atgaccatct tcttcctcat ggtggacatg
     5581 tagtgacgga ttacttaata cagaactaga agaacttcct acctcttccg tgttagagtg
     5641 tgatgggaga ttgttaagag atgacttagg aatatagtga tagtgttccc catgtcttac
     5701 tatataagca tcacctatat ctctgacaat atcattaggg ttaaaaacat atgtggctgc
     5761 taattcacct gccgacaagt cactctcagg aatgaaatga tagtgaccac catgtggtac
     5821 tatagtaggt tgaaatagaa tatgagcaaa ttgataaggg gattttaaag taatttctaa
     5881 caatgattta gaaactatga tgtgctattc taaattcaac tcactatata taaccatcat
     5941 cggtagtata acgtccctgt aattttgcta cagatacttc tgcactagct cctttatcgt
     6001 ctttaccatg ttcttgtttt tggcgattga tttcatcttt tgttcgtaca ttttctgcat
     6061 gagcttaatc tttaaggtaa acataatact ttccatctac cttaatacta tatcctccct
     6121 taacctaact gacgatatct tgatctttcg gctgatagtt gggggctttc attaatggct
     6181 cttcactaaa gagcgcatca aaaggaactt taccattata gcagtgataa tgatcgccat
     6241 gagaagttac ataaccttga cctgtaatct taataacaat ttgttttgct tgaattcctt
     6301 ctttttgact aacctagtct ggagtcaaat tttcagtctt cttagtgtct ttattactgt
     6361 ttacatatga aacacgattt ttatctgtat tggcctgtta gctatgttgg ttcagagcat
     6421 aaacacacag acttaaggaa aggataacaa cagatccagc tgctatatat ttctttttaa
     6481 atttcataat tacctcattt ctataattat ttatatgatg tcttcattat taaacga
//
LOCUS       DBEJAU010000076         5972 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC323 isolate 683620
            SAMN38261939-rid24807223.denovo.076, whole genome shotgun sequence.
ACCESSION   DBEJAU010000076 DBEJAU010000000
VERSION     DBEJAU010000076.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261939
            Sequence Read Archive: SRR26833919
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 5972)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5972)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576303.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576303.1
            Genome Coverage       :: 154x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/19/2025 01:05:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,121
            CDSs (total)                      :: 2,078
            Genes (coding)                    :: 1,943
            CDSs (with protein)               :: 1,943
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 36
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 72 of 135
            Pseudo Genes (incomplete)         :: 63 of 135
            Pseudo Genes (internal stop)      :: 51 of 135
            Pseudo Genes (multiple problems)  :: 46 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5972
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261939-rid24807223.denovo.076"
                     /strain="GPSC323"
                     /isolate="683620"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            117..3218
                     /locus_tag="ACL29Z_001962"
     CDS             117..3218
                     /locus_tag="ACL29Z_001962"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000561528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0008408 - 3'-5' exonuclease activity
                     [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit alpha"
                     /protein_id="HGR0070212.1"
                     /translation="MIAQLDTKTVYSFMESVISIEKYVRAAKEYGYTHLAMMDIDNLY
                     GAFDFLEITKKYGIHPLLGLEMTVFVDDQEVNLRFLALSSVGYQQLMKLSTAKMQGEK
                     TWSVLSQYLEDIAVIVPYFDRVESLELGCDYYIGVYPETLASEFHHPILPLYRVNAFE
                     SRDREVLQVLTAIKENLPLREVPLRSRQDVFISASSLEKLFQERFPQALDNLEKLISG
                     ISYDLDISLKLPRFNPARPAVEELRERAELGFVQKGLTSKEYQDRLDQELSVIHDMGF
                     DDYFLVVWDLLRFGRSNGYYMGMGRGSAVGSLVSYALDITGIDPVEKNLIFERFLNRE
                     RYTMPDIDIDIPDIYRPDFIRYVGNKYGSKHAAQIVTFSTFGAKQALRDVLKRFGVPE
                     YELSAITKKISFRDNLKSAYEGNLQFRQQINSKLEYQKAFEIACKIEGYPRQTSVHAA
                     GVVISDQDLTNYIPLKYGDEIPLTQYDAHGVEASGLLKMDFLGLRNLTFVQKMQELLA
                     ETEGIHLKIEEIDLEDKETLDLFASGNTKGIFQFEQPGAIRLLKRVQPVCFEDVVATT
                     SLNRPGASDYINNFVARKHGQEEVTVLDSALEDILAPTYGIMLYQEQVMQVAQRFAGF
                     SLGKADILRRAMGKKDASAMHEMRASFIQGSIEAGHTAEKAEQVFDVMEKFAGYGFNR
                     SHAYAYSALAFQLAYFKTHYPAIFYQVMLNYSNSDYLIDALEAGFEVASLSINTIPYH
                     DKIANKSIYIGLKSIKGLSKDLALWIIEHRPYSNIEDFIAKLPENYLKLPLLEPLVKV
                     GLFDSFEKNRQKVFNNLANLFEFVKELGSLFGDAIYSWQESEDWTEQEKFYMEQELLG
                     IGVSKHPLQAIASKAIYPITPIGNLSENSYAIILVEVQKIKVIRTKKGENMAFLQADD
                     SKKKLDVTLFSDLYRQVGQEIKEGAFYYVKGKIQSRDGRLQMIAQEIREAVAERFWIQ
                     VKNHESDQEISRILEQFKGPIPVIIRYEEEQKTIVSPHHFVAKSNELEEKLNEIVMKT
                     IYR"
     gene            3301..4308
                     /gene="pfkA"
                     /locus_tag="ACL29Z_001963"
     CDS             3301..4308
                     /gene="pfkA"
                     /locus_tag="ACL29Z_001963"
                     /EC_number="2.7.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000820836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006002 - fructose 6-phosphate metabolic
                     process [Evidence IEA];
                     GO_process: GO:0006096 - glycolytic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="6-phosphofructokinase"
                     /protein_id="HGR0070213.1"
                     /translation="MKRIAVLTSGGDAPGMNAAIRAVVRQAISEGMEVFGIYDGYAGM
                     VAGEIHPLDAASVGDIISRGGTFLHSARYPEFAQLEGQLKGIEQLKKHGIEGVVVIGG
                     DGSYHGAMRLTEHGFPAIGLPGTIDNDIVGTDFTIGFDTAVTTAMDAIDKIRDTSSSH
                     RRTFVIEVMGRNAGDIALWAGIATGADEIIIPEAGFKMEDIVASIKAGYECGKKHNII
                     VLAEGVMSAAEFGQKLKEAGDTSDLRVTELGHIQRGGSPTARDRVLASRMGAHAVKLL
                     KEGIGGVAVGIRNEKMVENPILGTAEEGALFSLTAEGKIVVNNPHKADIELSSLNKSL
                     S"
     gene            4367..5872
                     /gene="pyk"
                     /locus_tag="ACL29Z_001964"
     CDS             4367..5872
                     /gene="pyk"
                     /locus_tag="ACL29Z_001964"
                     /EC_number="2.7.1.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000287 - magnesium ion binding [Evidence
                     IEA];
                     GO_function: GO:0004743 - pyruvate kinase activity
                     [Evidence IEA];
                     GO_function: GO:0030955 - potassium ion binding [Evidence
                     IEA];
                     GO_process: GO:0006096 - glycolytic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate kinase"
                     /protein_id="HGR0070214.1"
                     /translation="MNKRVKIVATLGPAVEIRGGKKFGEDGYWGEKLDVEASAKNIAK
                     LIEAGANTFRFNFSHGDHQEQGERMATVKLAEKIAGKKVGFLLDTKGPEIRTELFEGE
                     AKEYSYKTGEKIRVATKQGIKSTREVIALNVAGALDIYDDVEVGRQVLVDDGKLGLRV
                     VAKDDATREFEVEVENDGIIAKQKGVNIPNTKIPFPALAERDNDDIRFGLEQGINFIA
                     ISFVRTAKDVNEVRAICEETGNGHVQLFAKIENQQGIDNLDEIIEAADGIMIARGDMG
                     IEVPFEMVPVYQKMIIKKVNAAGKVVITATNMLETMTEKPRATRSEVSDVFNAVIDGT
                     DATMLSGESANGKYPLESVTTMATIDKNAQALLNEYGRLDSDSFERNSKTEVMASAVK
                     DATNSMDIKLVVTLTKTGHTARLISKYRPNADILALTFDELTERGLMLNWGVIPMLTD
                     APSSTDDMFEIAERKAVEAGLVESGDDIVIVAGVPVGEAVRTNTMRIRTVR"
BASE COUNT         1855 a         1034 c         1351 g         1732 t
ORIGIN      
        1 caaaaataca aatgaataga aaataaatta gtaagctgat gaaatttttc tcaagagaag
       61 ccatttatag gtgaaaatgg tataatatag tgagaaggat agaggagaag tgtaaattga
      121 tcgcacaact agatacaaaa acagtctata gttttatgga aagcgtcatt tcgatcgaaa
      181 agtatgtgag agcagctaaa gaatacggct acactcattt ggctatgatg gatattgaca
      241 atctttatgg cgctttcgac tttctagaga ttacaaaaaa atacggcatt catcctttgc
      301 tagggcttga aatgacagtg tttgtagatg atcaggaagt gaatttgcgc tttttagctc
      361 tatctagtgt gggctatcag cagttgatga agctttcgac agccaagatg cagggggaga
      421 aaacttggtc agtcctgtcc cagtacctgg aggatatcgc ggtcattgtg ccttattttg
      481 atagagttga gtcgttagaa ctaggctgtg attactatat aggggtttat ccagaaacac
      541 tagcaagcga atttcatcat cctatcttac ctctttatcg ggtcaacgct tttgaaagca
      601 gggatagaga agttcttcaa gttttaacag cgattaaaga aaatctaccg ctcagagaag
      661 ttcccttgcg ttcgagacaa gatgtcttta tatcagcaag ttctttagag aaactattcc
      721 aagagcgttt tccgcaagct ttggacaatt tagaaaagct tatttcaggc atttcttacg
      781 acttggatat tagtctgaaa ctgcctcgtt ttaatccagc tagaccagca gtagaggagt
      841 tgagagagcg tgctgaactg gggtttgttc agaaggggtt gactagtaaa gaatatcaag
      901 atagactaga ccaagaattg tctgttattc atgatatggg ctttgatgat tatttcttgg
      961 ttgtttggga tttgttgcgt tttggacgat cgaatggcta ttatatggga atgggaaggg
     1021 gttctgcagt aggcagtttg gtttcttatg ccttagacat cacggggatt gacccagtag
     1081 agaaaaatct gatttttgaa cgctttctta atcgtgaacg ctataccatg cctgatattg
     1141 atattgatat cccagatatt tatcgtccag attttatcag atatgttggt aataaatatg
     1201 gtagtaaaca tgcggcacaa atcgttactt tttcaacctt tggagccaag caagctcttc
     1261 gagatgtctt gaaacgcttt ggtgtgccag agtatgaatt atctgcaatt actaagaaaa
     1321 tcagttttcg tgacaatctt aagtcggcct atgagggcaa tctccagttt cgtcagcaaa
     1381 tcaatagtaa gttagaatac caaaaagctt ttgagattgc ttgcaagata gagggctatc
     1441 caaggcaaac ctctgtccat gcggctggtg ttgtaattag tgaccaagat ttaaccaact
     1501 acattcctct aaagtatggt gatgaaattc cactgactca gtatgatgct catggagttg
     1561 aggctagcgg acttttgaag atggactttc tgggactacg aaatttgacc tttgtccaga
     1621 agatgcaaga gttgcttgct gaaacagaag gtattcacct taaaattgaa gaaatagatt
     1681 tggaagacaa agaaacgtta gatttatttg cctctggaaa tacaaaaggt atctttcaat
     1741 ttgagcaacc tggtgccatt cgcttgctca aacgtgttca accagtctgt tttgaagatg
     1801 tcgtagcaac tacttctcta aatcgaccag gtgcaagtga ctacatcaat aattttgtgg
     1861 caaggaagca tgggcaggaa gaagtgactg ttctagattc agctctggag gatattttgg
     1921 ctccaactta tggcattatg ctctatcagg agcaggttat gcaggttgct cagcgatttg
     1981 ctggatttag tcttgggaag gccgatattt tgcgtcgagc tatgggtaaa aaggatgcct
     2041 ctgctatgca tgagatgagg gcttccttta ttcaaggctc catagaagca ggccatactg
     2101 cggaaaaagc agagcaggtt tttgatgtta tggagaagtt tgcaggttat ggatttaata
     2161 gatctcatgc ctacgcctac tcagccttgg ccttccagtt ggcttatttc aaaacgcatt
     2221 atccagccat tttttatcag gtcatgttaa attattccaa cagtgattac ttaatagatg
     2281 cacttgaagc aggttttgaa gtagcctctc tatccatcaa tactattccc tatcacgata
     2341 aaattgccaa caagtctatc tatataggtt tgaaatcgat taaggggctc agcaaggact
     2401 tggcgctttg gattattgaa catagacctt attctaacat tgaagatttt atagctaaat
     2461 tacctgagaa ttatctgaaa cttcctctgc tagaaccttt ggtaaaagtt ggtcttttcg
     2521 attcatttga aaaaaatcgt caaaaagtat ttaataactt agctaatcta tttgaatttg
     2581 tgaaagagtt gggaagtttg tttggagatg ctatttatag ttggcaggaa tcggaagatt
     2641 ggacggaaca agaaaaattt tatatggaac aagagctttt agggataggt gtcagcaaac
     2701 atccactaca agctattgca agtaaggcta tttacccgat taccccaatc ggaaatttgt
     2761 cagaaaatag ctatgctatt attttggttg aagttcagaa aataaaagtg attcgtacca
     2821 aaaagggtga aaatatggcc ttcttacagg cagatgatag taagaaaaaa ttggatgtca
     2881 ctctcttttc agacttatat cgtcaggttg gacaggaaat aaaagaggga gccttctact
     2941 atgtaaaagg aaaaatacaa tcacgtgatg gccgtctgca aatgattgca caagaaataa
     3001 gagaagcagt tgctgaacgc ttttggatac aggtgaaaaa tcatgaatcg gatcaagaaa
     3061 tttcacgcat tttagaacaa tttaaaggcc caatcccagt catcatccgg tatgaagagg
     3121 aacagaaaac catcgtttct ccccatcatt ttgtagctaa atccaatgaa ttagaggaga
     3181 aattgaatga aatcgttatg aaaacgattt atcgctaaaa atacggaaaa tagaagaatt
     3241 ttaaaatcaa atgtgatata atcaagaaga atgttaaaag aaaaaggagc ataaaccaat
     3301 atgaaacgta ttgctgtttt gactagtggc ggagacgcac ctggtatgaa cgctgccatc
     3361 cgtgcagttg ttcgtcaagc aatttcagaa ggaatggaag tgtttggtat ctatgacgga
     3421 tatgctggta tggttgccgg tgaaattcat cccctagatg cagcttcagt aggggacatc
     3481 atttctcgtg gtggtacttt tcttcactca gctcgttatc cagagttcgc tcaacttgaa
     3541 gggcaactta aagggattga gcaattgaaa aaacacggaa ttgaaggtgt agttgttatc
     3601 ggtggtgacg gatcttacca cggcgctatg cgtttgactg aacatggctt cccagctatt
     3661 ggtcttccag gtacaatcga taacgatatc gttggtactg actttacaat cggttttgac
     3721 acagcggtta ctactgccat ggacgctatc gataagattc gtgatacatc atcaagtcac
     3781 cgtcgtactt ttgtaatcga agttatggga cgtaacgctg gtgatatcgc tctttgggct
     3841 ggtattgcaa ctggtgctga tgaaatcatc atccctgaag caggcttcaa gatggaagat
     3901 atcgtagcaa gcatcaaagc tggttatgaa tgtggtaaaa aacacaatat catcgtctta
     3961 gctgaaggtg tgatgtcagc ggctgaattt ggtcaaaaac ttaaagaagc tggagataca
     4021 agcgaccttc gtgtaacaga acttggacat attcaacgtg gtggttctcc aactgcgcgt
     4081 gaccgtgttt tggcgtcacg tatgggtgca catgctgtta aacttcttaa agaaggtatc
     4141 ggtggtgttg cggttggtat tcgtaacgaa aaaatggttg aaaatccaat tcttggtact
     4201 gcagaagaag gggcattgtt tagccttact gcagaaggta agattgtggt taacaacccg
     4261 cacaaagccg atattgagct atctagcttg aataagagct tgtcataatt tacaatttag
     4321 ttaataagac caaaaaggtc atatatataa aggagtcaca aaaatcatga acaaacgtgt
     4381 aaagatcgtt gcaactttgg gtcctgcggt agaaatccgt ggtggtaaaa aattcggtga
     4441 ggatggatac tggggtgaaa aacttgatgt tgaagcttca gctaaaaaca ttgctaaatt
     4501 gattgaagct ggtgctaaca cattccgatt caacttctca cacggcgacc accaagaaca
     4561 aggtgagcgt atggcaactg ttaaacttgc ggaaaaaatt gcaggtaaaa aagttggttt
     4621 ccttcttgat acaaaaggac ctgaaatccg tacagaattg ttcgaaggtg aagctaaaga
     4681 atattcatac aaaactggtg aaaaaattcg tgttgcaact aaacaaggaa tcaaatcaac
     4741 tcgtgaagtg attgcgttga acgttgctgg tgctcttgat atctatgatg atgttgaagt
     4801 tggtcgtcaa gttttggttg acgatggtaa acttggtctt cgtgtggttg ctaaagatga
     4861 tgcaactcgt gaatttgaag ttgaagttga aaacgatggt atcatcgcta aacaaaaagg
     4921 tgtgaacatc cctaacacta aaattccttt cccagctctt gctgaacgcg ataacgacga
     4981 tatccgtttc ggtcttgaac aaggtatcaa cttcatcgca atttcattcg tacgtactgc
     5041 aaaagatgtg aacgaagttc gtgcaatctg tgaagaaact ggaaacggac atgttcaatt
     5101 gttcgctaaa atcgaaaacc aacaaggtat cgataactta gacgaaatca tcgaagcagc
     5161 tgatggtatt atgattgctc gtggtgatat gggtatcgaa gtaccgttcg aaatggttcc
     5221 agtttatcaa aaaatgatta tcaagaaagt caatgctgca ggtaaagttg ttattactgc
     5281 aacaaacatg cttgaaacaa tgactgaaaa accgcgtgca actcgttcag aagtatcaga
     5341 cgtattcaac gctgttatcg acggaactga cgctacaatg ctgtcaggcg agtctgcaaa
     5401 cggtaaatac ccactcgagt cagtaactac aatggctaca atcgacaaga acgctcaagc
     5461 tcttcttaat gaatacggac gtcttgattc agattcattt gagcgtaact ctaagacaga
     5521 agtaatggct tctgctgtta aagatgctac taactcaatg gatatcaaat tggttgtaac
     5581 tcttactaag acaggtcata ctgcacgttt gatttctaaa taccgtccaa atgctgacat
     5641 cttagcattg acatttgacg aattgacaga acgtggcttg atgttgaact ggggtgttat
     5701 cccaatgttg acagatgctc catcttcaac tgacgatatg ttcgaaatcg ctgaacgtaa
     5761 agcggtagaa gcaggtctcg ttgagtcagg cgatgatatc gttatcgttg ctggtgtgcc
     5821 agtaggagaa gctgttcgca caaacacaat gcgtatccgc acagtacgtt aagaaaaata
     5881 taaaaaccta tcatatccag ctttctagcc tgtatgatgg gctctttttt tgtccagggg
     5941 gcaaaaaggg ggcaaaactt tcataatgga tt
//
LOCUS       DBEJAU010000077         5949 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC323 isolate 683620
            SAMN38261939-rid24807223.denovo.077, whole genome shotgun sequence.
ACCESSION   DBEJAU010000077 DBEJAU010000000
VERSION     DBEJAU010000077.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261939
            Sequence Read Archive: SRR26833919
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 5949)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5949)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576303.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576303.1
            Genome Coverage       :: 154x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/19/2025 01:05:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,121
            CDSs (total)                      :: 2,078
            Genes (coding)                    :: 1,943
            CDSs (with protein)               :: 1,943
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 36
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 72 of 135
            Pseudo Genes (incomplete)         :: 63 of 135
            Pseudo Genes (internal stop)      :: 51 of 135
            Pseudo Genes (multiple problems)  :: 46 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5949
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261939-rid24807223.denovo.077"
                     /strain="GPSC323"
                     /isolate="683620"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            203..1648
                     /gene="cps4A"
                     /locus_tag="ACL29Z_001965"
     CDS             203..1648
                     /gene="cps4A"
                     /locus_tag="ACL29Z_001965"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000091082.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="capsular polysaccharide biosynthesis protein
                     Cps4A"
                     /protein_id="HGR0070215.1"
                     /translation="MSRRFKKSGSQKVKRSVNIVLLTIYLLLVCFLLFLIFKYNILAF
                     RYLNLVVTALVLLVALVGLLLIIYKKAEKFTIFLLLFSILVSSVSLFAVQQFVGLTNR
                     LNATSNYSEYSISVAVLADSDIENVTQLTSVTAPTGTDNENIQKLLADIKSSQNTDLT
                     VNQSSSYLAAYKSLIAGETKAIVLNSVFENIIESEYPDYASKIKKIYTKGFTKKVEAP
                     KTSKNQSFNIYVSGIDTYGPISSVSRSDVNILMTVNRDTKKILLTTTPRDAYVPIADG
                     GNNQKDKLTHAGIYGVDSSIHTLENLYGVDINYYVRLNFTSFLKMIDLLGGVDVHNDQ
                     EFSALHGKFYFPVGNVHLDSEQALGFVRERYSLADGDRDRGRNQQKVIVAILQKLTST
                     EALKNYSTIINSLQDSIQTNMPLETMINLVNAQLESGGNYKVNSQDLKGTGRTDLPSY
                     AMPDSNLYVMEIDDSSLAVVKAAIQDVMEGR"
     gene            1650..2381
                     /gene="cps4B"
                     /locus_tag="ACL29Z_001966"
     CDS             1650..2381
                     /gene="cps4B"
                     /locus_tag="ACL29Z_001966"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000565374.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="capsular polysaccharide biosynthesis protein
                     Cps4B"
                     /protein_id="HGR0070216.1"
                     /translation="MIDIHSHIVFDVDDGPKSIEESKALLREAYNQGVRMIVSTSHRR
                     KGMFETPEEKIATNFIKVREIAKEVADDLVIAYGAEIYYTLDALEKLEKKEIPTLNDS
                     RYALIEFSMHTSYREIHAGLSNILMLGITPVIAHIERYDALENNEKRVRELIDMGCYT
                     QINSYHVLKPKFFGEKYKFMKKRARYFLERDLVHVVASDMHNLDSRPPYMQQAYDIIA
                     KKYGAKKAKEFFVDNPRKIIMDQLI"
     gene            2390..3082
                     /gene="cpsC"
                     /locus_tag="ACL29Z_001967"
     CDS             2390..3082
                     /gene="cpsC"
                     /locus_tag="ACL29Z_001967"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000664160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="capsular polysaccharide biosynthesis protein
                     CpsC"
                     /protein_id="HGR0070217.1"
                     /translation="MKEQNTLEIDVLQLFRTLWKRKLVILLVAIITSSVAFAYSTFVI
                     KPEFTSTTRIYVVNRNQEEKSGLTNQDLQAGSYLVKDYREIILSQDVLEEVISDLKLD
                     LTPKGLANKIKVTVPVDTRIVSVSVNDRVPEEASRIANSLREVAAQKIISITRVSDVT
                     TLEEARPAISPSSPNIKRNTLIGFLAGGIGTSVIVFLLELLDTHVKRPEDIEDTLQMT
                     LLGVVPNLSKLK"
     gene            3092..3775
                     /locus_tag="ACL29Z_001968"
     CDS             3092..3775
                     /locus_tag="ACL29Z_001968"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001142521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-protein kinase"
                     /protein_id="HGR0070218.1"
                     /translation="MPTLEIAQKKLEFIKKAEEYYNALCTNIQLSGDKLKVISVTSVN
                     PGEGKTTTSVNIARSFARAGYKTLLIDGDTRNSVISGVFKSREKITGLTEFLSGTADL
                     SHGLCDTNIENLFVIQSGSVSPNPTALLQGKNFNDMIETLRKYFDYIIVDTAPIGIVI
                     DAAIITQKCDASILVTATGEVNKRDVQKAKQQLEQTGKLFLGVILNKFDVQHKKYGSY
                     GDYGNYGKK"
     gene            3791..5158
                     /locus_tag="ACL29Z_001969"
     CDS             3791..5158
                     /locus_tag="ACL29Z_001969"
                     /EC_number="2.7.8.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001013545.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0016740 - transferase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sugar transferase"
                     /protein_id="HGR0070219.1"
                     /translation="MDEKGLKIFLAILQSIIVILLVYFLSFVRETELERSSIVILYLL
                     HFFVFYFSSYGNNFFKRGHLVEFNSTIRYIFFFAIAISVLNFFIAERFSISRRGMVYF
                     LTLEGISLYLLNFLVKKYWKHVFFNLKNSKKILLLTVTKNMEKVLDKLLESDELSWKL
                     VAVSVLDKSDFQHDKIPVIEKEKIIEFATHEVVDEVFVNLPGESYDIGEIISRFETMG
                     IDVTVNLKAFDKNLGRNKQIHEMVGLNVVTFSTNFYKTSHMISKRILDICGATIGLVL
                     FAIASLVLVPLIRKDGGPAIFAQTRIGKNGRHFTFYKFRSMRIDAEAIKEQLMDQNTM
                     QGGMFKMDNDPRVTKIGRFIRKTSLDELPQFWNVFIGDMSLVGTRPPTVDEYDQYTPE
                     QKRRLSFKPGITGLWQVSGRSKITDFDDVVKLDVAYIDNWTIWKDIEILLKTVKVVFI
                     RDGAK"
     gene            5162..5611
                     /gene="pssD"
                     /locus_tag="ACL29Z_001970"
     CDS             5162..5611
                     /gene="pssD"
                     /locus_tag="ACL29Z_001970"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017650132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016740 - transferase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PssD/Cps14F family polysaccharide biosynthesis
                     glycosyltransferase"
                     /protein_id="HGR0070220.1"
                     /translation="MKVCLVGSSGGHLTHLYLLKPFWKDKERFWVTFDKEDARSILGN
                     EIFYSCHYPTNRNLKNLIKNTILAFNILRKEHPDIIVSSGAAVAVPFFYLGKIFGAKT
                     VYIEVFDRIDAPTMTGKLVYPVTDRFIVQWEEMKKVYPKAINLGGIF"
     gene            5611..>5949
                     /locus_tag="ACL29Z_001971"
     CDS             5611..>5949
                     /locus_tag="ACL29Z_001971"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336534.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016758 - hexosyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HGR0070221.1"
                     /translation="MIFVTVGTHEQQFDRLIKEVDRLKKENLIQDEVFIQTGYSKYIP
                     KYCEWEKIISYEKMNQLIEKSDIVITHGGPATFMGVIAKGKIPIVVPRQKKFEEHVND
                     HQLEFCNKVKQ"
BASE COUNT         1985 a          865 c         1205 g         1894 t
ORIGIN      
        1 ttagattgaa actagaatag tacacatctg cttctaaaac attgttagaa atcgatttga
       61 ctgtccttat ttcattttat tatatttttg gttcgcggga agtctactaa gatacttaaa
      121 gatgcagata gtaaaaaaaa atgtagacat taccgtaaaa aagtgatata atcgtatgat
      181 gttcaaggta taggtgttaa tcatgagtag acgttttaaa aaatcaggtt cacagaaagt
      241 gaagcgaagt gttaatatcg ttttgctgac tatttattta ttgttagttt gttttttatt
      301 gttcttaatc tttaagtaca atatccttgc ttttagatat cttaacctag tggtaactgc
      361 gttagtccta ctagttgcct tggtagggct actcttgatt atctataaaa aagctgaaaa
      421 atttactatt tttctgttgc tgttctctat ccttgtcagc tctgtgtcgc tctttgcagt
      481 acagcagttt gttggactga ccaatcgttt aaatgcgact tctaattact cagaatattc
      541 aatcagtgtc gctgttttag cagatagtga tatcgaaaat gttacgcaac tgacgagtgt
      601 gacagcaccg actgggactg ataatgaaaa tattcaaaaa ctactagctg atatcaagtc
      661 aagtcagaat accgatttga cggtcaacca gagttcgtct tacttggcag cttacaagag
      721 tttgattgca ggggagacta aggccattgt cctaaatagt gtctttgaaa atatcatcga
      781 gtcagagtat ccagactacg catcgaagat aaaaaagatt tataccaagg gattcactaa
      841 aaaagtagaa gctcctaaga cgtctaagaa tcagtctttc aatatctatg ttagtggaat
      901 tgacacctat ggtcctatta gttcggtgtc gcgatcagat gtcaatatcc tgatgactgt
      961 caatcgagat accaagaaaa tcctcttgac cacaacgcca cgtgatgcct atgtaccaat
     1021 cgcagatggt ggaaataatc aaaaagataa attaacccat gcaggcattt atggagttga
     1081 ttcgtccatt cacaccttag aaaatctcta tggagtggat atcaattact atgtgcgatt
     1141 gaacttcact tctttcttga aaatgattga cttattggga ggggtagatg ttcataatga
     1201 tcaagagttt tcagctctac atgggaagtt ctatttccca gtagggaatg tccatctaga
     1261 ctctgagcag gctctaggtt ttgtacgtga acgctactca ctagccgatg gagaccgtga
     1321 ccgtggtcgc aaccaacaaa aggtgattgt ggctatcctt caaaaattaa cgtcaaccga
     1381 agcactgaaa aattatagta cgatcattaa tagcttgcaa gattctatcc aaacaaatat
     1441 gccacttgag actatgataa atttggtcaa tgctcagtta gaaagtggag ggaattataa
     1501 agtaaattct caagatttaa aaggtacagg tcggacggat cttccttctt atgcaatgcc
     1561 agacagtaac ctctatgtga tggaaataga tgatagtagt ttagctgtag ttaaagcagc
     1621 tatacaggat gtgatggagg gtagatgaaa tgatagacat ccattcgcat atcgtttttg
     1681 atgtagatga cggtcccaag tcaatagagg aaagcaaggc acttttaaga gaagcttata
     1741 atcaaggagt tcgaatgatt gtgtctactt cgcatcgtcg aaaagggatg tttgaaactc
     1801 cagaagaaaa aattgcaaca aattttatta aggttcgtga aattgcaaaa gaagtagcag
     1861 atgatttagt catagcttat ggcgcagaga tatactatac tctggatgct ctagaaaagc
     1921 tagaaaaaaa agaaattcct acccttaatg atagtcgtta tgctttgatt gagtttagca
     1981 tgcatacttc ctatcgtgag attcatgcgg gattgagcaa tattttgatg ttgggaatca
     2041 cgccagtaat tgctcatatt gaacgttatg atgccttaga gaataacgaa aaacgtgttc
     2101 gtgaactgat tgatatgggg tgctatactc agataaatag ttatcatgtt ttaaaaccta
     2161 agttctttgg tgaaaaatat aaattcatga aaaagagagc tcggtatttt ttggaacgtg
     2221 atttagttca tgtagttgca agtgacatgc acaatttaga cagtagacct ccatatatgc
     2281 aacaggcata tgatatcatt gctaagaaat atggagcgaa aaaagcgaaa gaattttttg
     2341 tagataatcc cagaaaaatt ataatggatc aattaattta ggagaaaata tgaaggaaca
     2401 aaacactttg gaaatcgatg tattgcaact attcagaact ttatggaaaa gaaagttggt
     2461 cattttatta gtggcaatta taacttcttc agttgctttt gcctacagta cttttgttat
     2521 caaacctgag tttactagta cgactcggat ttatgtagtt aaccgtaatc aggaagagaa
     2581 gtctggttta accaatcaag acttgcaggc aggatcatac ttggtcaaag actatcgtga
     2641 aattatccta tcgcaggatg ttttggagga agttatttct gatttgaaac tagatttgac
     2701 gccaaaaggt ttggctaata aaattaaagt aacagtacca gttgataccc gtattgtctc
     2761 tgtttcagtt aatgatcgag ttcctgaaga ggcaagccgt atcgctaact ctttgagaga
     2821 agtagctgct caaaaaatta tcagtattac tcgtgtttct gatgtgacaa cactggagga
     2881 agcaagaccg gcgatatcac catcttcgcc aaatattaaa cgcaatacac taattggttt
     2941 tttggcaggg gggattggaa ctagtgttat agtttttctt cttgaacttt tggacactca
     3001 tgtgaaacgt ccggaagata tcgaagatac actgcagatg acacttttgg gagttgtacc
     3061 aaacttgagt aagttgaaat aggagagagg aatgccgaca ttagaaatag cacaaaaaaa
     3121 actggagttc attaagaagg cagaagaata ttacaatgcc ttgtgtacaa atatacagtt
     3181 gagcggagat aaactaaaag taatttccgt tacttctgtt aaccctgggg aaggaaaaac
     3241 aactacttcc gtaaatatag caaggtcgtt tgcgcgtgca ggctataaaa ctcttttgat
     3301 cgatggcgat actcgaaatt ccgttatatc aggagttttt aaatcgcgtg aaaaaattac
     3361 agggctaaca gaatttttat ctgggacagc tgatttatct cacggtttat gtgatacaaa
     3421 tattgaaaat ttatttgtaa ttcaatcggg atctgtatca ccaaacccta cagccttgtt
     3481 acaaggtaaa aattttaatg atatgattga aacattgcgt aaatattttg attatatcat
     3541 tgttgataca gcacctattg gaattgttat tgatgcggca attatcactc aaaagtgtga
     3601 tgcgtccatc ttggtaacag caacaggtga ggtgaataaa cgtgatgtcc aaaaagcgaa
     3661 acaacaatta gaacaaacag ggaaactgtt tttaggtgtc attctcaata aatttgatgt
     3721 tcaacataaa aaatatggtt cttacggtga ctatggtaat tatggtaaaa aataacttag
     3781 gaaagatttt atggatgaaa aaggattgaa aatttttctg gcaatattac agagtattat
     3841 tgtcatttta ttggtttatt ttcttagctt tgttagagag acagaacttg aacgttcttc
     3901 gatagttata ctataccttc tccacttttt tgtattctat tttagttcct atggtaataa
     3961 tttttttaaa agagggcact tagttgagtt taatagtact ataagatata tttttttctt
     4021 tgcaatagct ataagtgtat taaacttttt tatagcggaa cggtttagta tctctagaag
     4081 aggaatggta tacttcttaa ctttagaagg aatatcctta tacttgttaa atttcttagt
     4141 aaagaaatat tggaagcatg tgttttttaa tctaaaaaat agcaagaaaa ttttactgtt
     4201 aacagtaacg aaaaatatgg aaaaagttct tgataaattg ctagaatctg atgaactttc
     4261 atggaaattg gtagcagtaa gtgttttgga taaatctgat tttcaacatg ataaaatacc
     4321 tgtaattgaa aaggaaaaaa ttattgaatt tgcaacgcat gaagttgtgg atgaggtgtt
     4381 tgtcaatctt ccaggggaga gctacgatat tggagaaatt atctctaggt ttgagacaat
     4441 ggggatagat gtaactgtaa atcttaaagc atttgataag aatttgggtc gcaataaaca
     4501 aattcatgag atggtaggat tgaatgtagt cactttctct acaaattttt ataaaactag
     4561 tcatatgatt tcaaagagaa ttctcgatat ttgtggtgcc actattggcc ttgttctttt
     4621 tgctatagct agtctagttt tagttccatt gattcgtaaa gatggcggac cagctatttt
     4681 tgctcaaact cgtataggga aaaatggtcg acattttacc ttttataaat tccgttcgat
     4741 gcggatcgat gctgaagcta tcaaagaaca attgatggat caaaatacga tgcaaggtgg
     4801 tatgtttaag atggacaatg atcctcgtgt tacaaaaatt ggtcgcttta ttcgtaaaac
     4861 cagtttggat gaattgccgc agttttggaa tgtctttata ggagatatga gtttggtggg
     4921 aacacgtcca cctacagtag acgagtatga tcagtatact ccagaacaga aacgtcgact
     4981 cagctttaaa cctggtatta caggtttatg gcaggttagc ggccgtagta aaataaccga
     5041 ttttgacgat gttgtaaaat tagatgtggc ttatattgat aattggacaa tctggaaaga
     5101 tattgaaatt ttgcttaaaa ctgttaaagt tgtatttata agagatggag cgaagtaagg
     5161 aatgaaagta tgtctagttg gatctagtgg aggccattta actcatttgt atttattaaa
     5221 acctttctgg aaagataaag aaagattttg ggttactttt gataaagaag atgcaagaag
     5281 tattttggga aatgaaatat tttactcatg tcattatcct actaatcgta atctaaaaaa
     5341 tcttattaaa aatacgattc ttgctttcaa tattttgaga aaggaacacc ctgatattat
     5401 cgtatcatca ggggcagctg tagcagttcc tttcttttat ctagggaaaa tatttggtgc
     5461 taagacagtc tatatagaag tatttgatag aattgatgct ccgacaatga cggggaaact
     5521 tgtttatcca gtaactgaca ggtttattgt ccaatgggaa gaaatgaaaa aagtataccc
     5581 aaaagcaatt aacctaggag ggatattcta atgatttttg tgactgtagg tacacatgaa
     5641 caacaatttg atcgattgat taaagaagtt gatcgtttaa aaaaagaaaa tcttattcaa
     5701 gatgaagtat ttattcaaac aggatattcc aaatatattc cgaaatattg tgagtgggaa
     5761 aagataattt cttatgaaaa aatgaatcaa ttgattgaga aatcagatat tgtcattact
     5821 catggtggac cagcgacgtt tatgggggtt attgctaaag gaaaaattcc gatagttgtt
     5881 cctagacaaa aaaaatttga agagcatgtg aatgaccatc agttagaatt ctgtaataaa
     5941 gtaaagcag
//
LOCUS       DBEJAU010000078         5736 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC323 isolate 683620
            SAMN38261939-rid24807223.denovo.078, whole genome shotgun sequence.
ACCESSION   DBEJAU010000078 DBEJAU010000000
VERSION     DBEJAU010000078.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261939
            Sequence Read Archive: SRR26833919
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 5736)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5736)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576303.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576303.1
            Genome Coverage       :: 154x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/19/2025 01:05:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,121
            CDSs (total)                      :: 2,078
            Genes (coding)                    :: 1,943
            CDSs (with protein)               :: 1,943
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 36
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 72 of 135
            Pseudo Genes (incomplete)         :: 63 of 135
            Pseudo Genes (internal stop)      :: 51 of 135
            Pseudo Genes (multiple problems)  :: 46 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5736
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261939-rid24807223.denovo.078"
                     /strain="GPSC323"
                     /isolate="683620"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            239..2563
                     /gene="pflB"
                     /locus_tag="ACL29Z_001972"
     CDS             239..2563
                     /gene="pflB"
                     /locus_tag="ACL29Z_001972"
                     /EC_number="2.3.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399021.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0008861 - formate C-acetyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="formate C-acetyltransferase"
                     /protein_id="HGR0070222.1"
                     /translation="MVVKTVVEAQDIFDKAWEGFKGVDWKEKASVSRFVQANYTPYDG
                     DESFLAGPTERSLHIKKIVEETKAHYEETRFPMDTRPTSIADIPAGFIDKENEVIFGI
                     QNDELFKLNFMPKGGIRMAETTLKENGYEPDPAVHEIFTKYVTTVNDGIFRAYTSNIR
                     RARHAHTVTGLPDAYSRGRIIGVYARLALYGADYLMQEKVNDWNAIKEIDEETIRLRE
                     EVNLQYQALQQVVRLGDLYGVDVRKPAMNVKEAIQWVNIAFMAVCRVINGAATSLGRV
                     PIVLDIFAERDLARGTFTESEIQEFVDDFVMKLRTVKFARTKAYDQLYSGDPTFITTS
                     MAGMGNDGRHRVTKMDYRFLNTLDNIGNSPEPNLTVLWTDKLPYNFRRYCMHMSHKHS
                     SIQYEGVTTMAKDGYGEMSCISCCVSPLDPENEEQRHNIQYFGARVNVLKALLTGLNG
                     GYDDVHKDYKVFDIEPIRDEVLEFESVKANFEKSLDWLTDTYVDALNIIHYMTDRYNY
                     EAVQMAFLPTKQRANMGFGICGFANTVDTLSAIKYATVKPIRDEDGYIYDYETIGDYP
                     RWGEDDPRSNELAEWLIEAYTTRLRSHKLYKDAEATVSLLTITSNVAYSKQTGNSPVH
                     KGVYLNEDGSVNLSKLEFFSPGANPSNKAKGGWLQNLNSLSSLDFSYAADGISLTTQV
                     SPRALGKTRDEQVDNLVTILDGYFENGGQHVNLNVMDLNDVYEKIMSGEDVIVRISGY
                     CVNTKYLTPEQKTELTQRVFHEVLSMDDALDALS"
     gene            complement(2701..3963)
                     /locus_tag="ACL29Z_001973"
     CDS             complement(2701..3963)
                     /locus_tag="ACL29Z_001973"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000400089.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
                     /protein_id="HGR0070223.1"
                     /translation="MEHINHTTLLIGIKDKNITLNKAIQHDTHIEVFATLDYHPPKCK
                     HCKGKQIKYDFQKPSKIPFIEIGGFPSLIHLKKRRFQCKSCRKVTVAETTLVQKNCQI
                     SEMVRQKIAQLLLNREALTHIASKLAISTSTSTVYRKLKQFHFQEDYTTLPEILSWDE
                     FSYQKGKLAFIAQDFNTKKIMTILDNRRQTTIRNHFFKYSKEARKKVKVVTVDMSGSY
                     IPLIKKLFPNAKIVLDRFHIVQHMSRALNQTRINIMKQFDDKSLEYRALKYYWKFILK
                     DSRKLSLKPFYARTFRETLTPRECLKKIFTLVPELKDYYDLYQLLLFHLQEKNTDQFW
                     GLIQDTLPHLNRTFKTTLSTFICYKNYITNAIELPYSNAKLEATNKLIKDIKRNAFGF
                     RNFENFKKRIFIALNIKKERTKFVLSQA"
     gene            complement(4228..>5736)
                     /gene="rlrA"
                     /locus_tag="ACL29Z_001974"
     CDS             complement(4228..>5736)
                     /gene="rlrA"
                     /locus_tag="ACL29Z_001974"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000933118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PI-1 pilus transcriptional regulator RlrA"
                     /protein_id="HGR0070224.1"
                     /translation="KRITDKITILNILLDIRSIELDELSTLTSLQSKSLLSILQELQE
                     TFEEELTFNLDTQQVQLIEHHSHQTNYYFHQLYNQSTILKILRFFLLQGNQSFNEFTQ
                     KEYISIATGYRVRQKCGLLLRSVGLDLVKNQVVGPEYRIRFLIALLQFHFGIEIYDLN
                     DGSMDWVTHMIVQSNSQLSHELLEITPDEYVHFSILVALTWKRREFPLEFPESKEFEK
                     LKNLFMYPILMEHCQTYLEPHANMTFTQEELDYIFLVYCSANSSFSKDKWNQEKKTHT
                     IQLILQHTRGKHLLSKFKNILGNDISNSLSFLTALTFLTRTFLFGLQNLVPYYNYYEH
                     YGIESDKPLYHISKAIVQEWMTEQKIEGVIDQHRLYLFSLYLTETIFSSLPAIPIFII
                     LNNQADVNLIKSIILRNFTDKVASVTGYNILISPPPSEEHLTEPLIIITTKEYLPYVK
                     KQYPKGKHHFLTIALDLHVSQQRLIYQTIVDIRKEAFDKRVAMIAKKAHYLL"
BASE COUNT         1781 a         1030 c         1165 g         1760 t
ORIGIN      
        1 ttcgatttcc attgagtgtt actgcttatt ttcttttatt ataccctttt ttctgaaaaa
       61 aagaaaaaag gactttattt tttcaaaaat ataatacagt ttgaaataaa atatagactg
      121 ttttagaaaa gaaagtgtaa aaatagggaa ttttcacttg ttgaaatcgg ttactatatg
      181 gtatacttgt cttatgaatg taacagatga ctgttactag aaaaaagagg acattaatat
      241 ggttgttaag acagttgttg aagcacaaga tatttttgac aaagcttggg aaggcttcaa
      301 aggcgtagat tggaaagaaa aagcaagtgt atcacgattt gtacaagcta actacacacc
      361 ttatgatgga gacgaaagct tccttgcagg accaacagag cgttcacttc acatcaagaa
      421 aattgtagaa gaaactaaag cacactacga agaaactcgt ttcccaatgg acactcgtcc
      481 aacatctatc gctgatatcc ctgctggatt tatcgacaaa gaaaatgaag ttatcttcgg
      541 tatccaaaac gatgaactct tcaaattgaa cttcatgcca aaaggtggta tccgtatggc
      601 tgaaactact ttgaaagaaa atggatacga accagaccca gctgttcacg aaatcttcac
      661 taaatatgta acaacagtta acgacggtat tttccgtgcc tacacttcaa atattcgtcg
      721 cgctcgtcac gcacacactg taactggtct tccagatgca tactcacgcg gacgtatcat
      781 cggtgtttac gcacgtcttg ctctttacgg tgcagactac ttgatgcaag aaaaagtaaa
      841 tgactggaat gcaatcaaag aaatcgatga agaaacaatc cgtcttcgtg aagaagtaaa
      901 ccttcaatac caagcattgc aacaagttgt tcgcctgggt gacctttacg gggttgatgt
      961 tcgcaaacca gcgatgaacg tgaaagaagc aatccaatgg gttaacattg ctttcatggc
     1021 tgtctgccgt gtgattaacg gtgctgctac atctctaggt cgtgtaccaa tcgtattgga
     1081 catctttgca gaacgtgacc ttgctcgtgg tacatttact gaatcagaaa tccaagaatt
     1141 cgttgatgat ttcgttatga aacttcgtac agttaaattt gctcgtacaa aagcttatga
     1201 ccaattgtac tcaggtgacc caacctttat cacaacttct atggctggta tgggtaacga
     1261 cggtcgtcac cgtgttacta agatggacta ccgtttcttg aacactcttg acaacatcgg
     1321 taactcacca gaaccaaact tgacagttct ttggactgac aaattgccat acaacttccg
     1381 tcgctactgt atgcacatga gccacaaaca ctcttctatc caatacgaag gtgtaacaac
     1441 aatggctaaa gacggatatg gtgaaatgag ctgtatctca tgctgtgtgt ctccacttga
     1501 tccagaaaat gaagaacaac gccacaacat ccagtacttc ggtgctcgtg taaacgttct
     1561 taaagccctt cttactggtt tgaatggtgg ttacgacgat gttcacaaag actacaaagt
     1621 atttgatatc gaaccaatcc gtgacgaagt tcttgaattt gaatcagtta aagcgaactt
     1681 tgaaaaatct cttgactggt tgactgacac ttacgtagat gccttgaaca tcatccacta
     1741 catgactgat aggtacaact acgaagctgt tcaaatggcc ttcttgccaa ctaaacaacg
     1801 tgccaacatg ggattcggta tctgtggatt tgctaacact gttgatacat tgtcagctat
     1861 caaatacgct acagttaaac caatccgtga cgaagatggc tacatctacg attacgaaac
     1921 aatcggtgac tacccacgct ggggtgaaga tgacccacgt tcaaacgaat tggcagaatg
     1981 gttgatcgaa gcttacacaa ctcgtctacg tagccacaaa ctatacaaag acgcagaagc
     2041 tacagtatca cttttgacaa tcacatctaa cgttgcttac tctaaacaaa ctggtaactc
     2101 accagttcac aaaggtgtat acctcaacga agatggttct gtgaacttgt ctaaacttga
     2161 attcttctca ccaggtgcta acccatctaa caaagctaaa ggtggttggt tgcaaaactt
     2221 gaactcactt tctagccttg actttagtta tgcagctgac ggtatctcat tgactacaca
     2281 agtatcacct cgcgctcttg gtaagactcg tgatgaacaa gttgataact tggtaacaat
     2341 ccttgatggt tacttcgaaa acggtggaca acacgttaac ttgaacgtta tggacttgaa
     2401 cgatgtttac gaaaaaatca tgtcaggcga agacgttatc gtacgtatct ctggatactg
     2461 tgtaaacact aaatacctca ctccagaaca aaaaactgaa ttgacacaac gtgtcttcca
     2521 cgaagttctt tcaatggatg acgccttgga tgcattgagc taatcaagtt cttgaataat
     2581 aaaaaggaac cctcggtcaa acgactgagg gttttgtgct tgggatagta tgagcaattc
     2641 cttcggcgca atatgcaatg tttttgggct ctttgtcaac tgtagtgggt tgaaaaaaag
     2701 ctaagcttga gaaaggacaa atttcgtcct ttcttttttg atgttcaggg cgataaaaat
     2761 ccgttttttg aagttttcaa agttccgaaa accaaaggca ttgcgcttga tgtctttgat
     2821 gagtttgtta gtggcctcaa gtttagcgtt agaataaggc aattcaatgg cgttagtgat
     2881 gtagttttta tagcaaataa atgtgctcaa agtggtttta aaggtgcggt tgagatgagg
     2941 taacgtgtct tgaattaagc cccaaaactg gtcagtattc ttctcttgta gatgaaatag
     3001 gagtagttga tacaggtcat agtaatcttt aagttcaggt actagagtaa agattttctt
     3061 cagacactcc ctaggagtta aggtctctct gaaagttcta gcatagaaag gcttaagaga
     3121 gagtttccga ctatctttta ggataaattt ccagtaatat ttaagagctc tgtattccag
     3181 agatttatca tcaaattgct tcatgatgtt gattctagtc tgattaagag ccctgctcat
     3241 gtgttggaca atgtggaaac gatcgagaac aattttagca ttgggaaata atttcttaat
     3301 gagagggata taacttccag acatatcaac agtgacgact ttaacttttt ttctagcttc
     3361 tttcgagtac ttgaagaaat gatttcggat ggttgtttga cgtctgttat caagaatggt
     3421 catgattttc ttagtgttga aatcctgagc aatgaaagcc aatttcccct tctggtagga
     3481 gaattcatcc caggagagga tttcaggcaa agtggtgtaa tcctcttgga aatgaaattg
     3541 cttgagctta cgatagacgg tagaggtaga ggtagagatg gctaatttag aagcgatatg
     3601 tgtaagagcc tctctgttga gtaggagttg ggcaattttc tgtctcacca tttccgagat
     3661 ttggcaattt ttctgaacga gagttgtttc agctacagtg actttccgac aggacttgca
     3721 ttgaaatcgt ctctttttca aatgaatgag gctagggaaa ccaccaatct cgataaaagg
     3781 gattttagaa ggcttttgga agtcgtattt gatttgtttt cctttacagt gtttacattt
     3841 aggtgggtga taatcaagtg tagcgaagac ttcgatatgg gtatcgtgct gaatggcttt
     3901 atttaaggtg atgtttttgt cttttattcc gatgagtaat gtggtatgat tgatgtgttc
     3961 cataagatac tttctaatga gttgtttagg cgcttttcat tataagtctt atgggacttt
     4021 tttgatactc aaaaagccct ataatctcca cagtgggatt tacccactac agaaattata
     4081 gagccagaaa aaacactttt gttcactagc agaaactaga gagcagaagt gtttttctgt
     4141 tcagatttac ccaaaactgg gaaatatggg gataagaata gagatggctt aggaagcccc
     4201 tttttgtgtg tagacagtac gatgaactta taacaaatag tgagcctttt tagcaatcat
     4261 tgcgacccgt ttgtcaaaag cctcttttcg gatatctaca attgtctgat agatgagacg
     4321 ctgttggcta acatgcaaat ctaaggcaat cgtcaaaaag tgatgtttcc ctttgggata
     4381 ctgcttttta acgtaaggca ggtattcttt cgttgtaata ataatcaatg gctctgtcaa
     4441 atgctcctct gaaggaggag gactaattag aatattgtat cctgtaacag aggcaacttt
     4501 gtcagtaaaa ttccgtaaaa taatggactt tattaagttt acatctgctt gattatttaa
     4561 aatgataaaa atcgggatag caggtagtga ggaaaagatg gtttctgtca agtagagtga
     4621 gaaaaggtac agccgatgct ggtcgataac tccttcaatc ttctgctcag tcatccactc
     4681 ttgaacaatt gctttcgaaa tatgatacag tggcttgtcg ctttcaatcc cataatgttc
     4741 gtaataatta taatagggaa ctagattttg taaaccaaac aaaaacgttc ttgttaagaa
     4801 agtcagtgct gttaaaaaag aaagagaatt cgaaatgtca tttcctaaga tattcttgaa
     4861 cttggatagt agatgctttc ctcttgtatg ctgaagaatc agttgaatag tatgagtctt
     4921 tttttcttga ttccatttgt ccttggaaaa cgaagaatta gcagaacaat aaaccaaaaa
     4981 gatataatcc agttcttcct gagtaaaagt catgttggca tgtggctcta agtaagtttg
     5041 gcaatgttcc atcaaaatcg gatacataaa gaggtttttt aatttttcaa actctttgga
     5101 ctcagggaac tcaagtggaa attcccgacg tttccaagtg agtgccacta gtatgctaaa
     5161 atgaacatac tcgtcaggtg tgatttctaa cagttcatga ctgagttgag aattagactg
     5221 cacaatcata tgtgtgaccc aatccatact tccatcattc aaatcataaa tctcaatacc
     5281 aaaatgaaac tggaggagtg caattaaaaa acgaatgcga tattcaggac caactacttg
     5341 atttttcaca aggtccaaac ctactgaacg tagtaacaag ccacactttt gtcgtacgcg
     5401 gtagcctgtt gcgatggaaa tatactcttt ttgtgtaaat tcgttaaagc tttgattacc
     5461 ttgtagtaga aagaagcgga gtatttttaa aatagttgat tggttataaa gctgatggaa
     5521 gtaataattc gtttgatgag aatggtgttc gattaattga acttgttgcg tatctaaatt
     5581 aaatgtcaac tcttcctcga atgtttcttg taattcctgc aaaatgctta ggagactttt
     5641 agattgtaat gaagttaaag tagacagttc atctagttca atagaccgaa tatccaataa
     5701 tatatttaaa atggtaattt tatctgtaat tctttt
//
LOCUS       DBEJAU010000079         5524 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC323 isolate 683620
            SAMN38261939-rid24807223.denovo.079, whole genome shotgun sequence.
ACCESSION   DBEJAU010000079 DBEJAU010000000
VERSION     DBEJAU010000079.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261939
            Sequence Read Archive: SRR26833919
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 5524)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5524)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576303.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576303.1
            Genome Coverage       :: 154x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/19/2025 01:05:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,121
            CDSs (total)                      :: 2,078
            Genes (coding)                    :: 1,943
            CDSs (with protein)               :: 1,943
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 36
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 72 of 135
            Pseudo Genes (incomplete)         :: 63 of 135
            Pseudo Genes (internal stop)      :: 51 of 135
            Pseudo Genes (multiple problems)  :: 46 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5524
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261939-rid24807223.denovo.079"
                     /strain="GPSC323"
                     /isolate="683620"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            170..370
                     /locus_tag="ACL29Z_001975"
     CDS             170..370
                     /locus_tag="ACL29Z_001975"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000226586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0070225.1"
                     /translation="MVVSASASSTSPQAQEQVDKSELRALSQELDQHLKALATVSDPK
                     IDATKAVLLDAQKAPEDSALTE"
     gene            395..811
                     /locus_tag="ACL29Z_001976"
     CDS             395..811
                     /locus_tag="ACL29Z_001976"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000642281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transmembrane domain-containing protein"
                     /protein_id="HGR0070226.1"
                     /translation="MKAALDSLKDVKANASDSKPAQDKKDAKQGTEDSKDSDKMTETN
                     SVPAGVIVVSLLALLGVIAFWLIRRKKESEIQQLSTELIKVLGQLDAEKADKKVLAKA
                     QNLLQETLDFVKEENGSAETETKLVEELKAILDKLK"
     gene            1042..1749
                     /gene="ccdA2"
                     /locus_tag="ACL29Z_001977"
     CDS             1042..1749
                     /gene="ccdA2"
                     /locus_tag="ACL29Z_001977"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004237834.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiol-disulfide oxidoreductase-associated
                     membrane protein CcdA2"
                     /protein_id="HGR0070227.1"
                     /translation="METIVFLISVFLAGVLSFFSPCIFPLLPVYAGILLDDQESAKSF
                     SLFGRKVLWSGLIRTLCFIAGISLIFFILGFGAGYFGHILYANWFRYGMGAIIIILGL
                     HQMEIFHLKKLEVQKSFTFKKSDSNRYWSAFLLGITFSFGWTPCIGPVLSSVLALAAS
                     GGNGAWQGAIYTLIYTLGMALPFLVLALASGLVMPYFSKIKRHMMLLKKIGGFLIVLM
                     GILLLLGQVNVLAGIFE"
     gene            1760..2317
                     /gene="sdbB"
                     /locus_tag="ACL29Z_001978"
     CDS             1760..2317
                     /gene="sdbB"
                     /locus_tag="ACL29Z_001978"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000757364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiol-disulfide oxidoreductase-associated
                     lipoprotein SdbB"
                     /protein_id="HGR0070228.1"
                     /translation="MKKVMFAGLSLLSLVVLMACGEEETKKTQAAQQPKQQTTVQQIA
                     VGKDAPDFTLQSMDGKEVKLSDFKGKKVYLKFWASWCGPCKKSMPELMELAAKPDRDF
                     EILTVIAPGIQGEKTVEQFPQWFQEQGYKDIPVLYDTKATTFQAYQIRSIPTEYLIDS
                     QGKIGKIQFGAISNADAEAAFKEMN"
     gene            2692..4083
                     /locus_tag="ACL29Z_001979"
     CDS             2692..4083
                     /locus_tag="ACL29Z_001979"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001020339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="APC family permease"
                     /protein_id="HGR0070229.1"
                     /translation="MNIFRTKNVSLDKTEMHRHLKLWDLILLGIGAMVGTGVFTITGT
                     AAATLAGPALVISIVISALCVGLSALFFAEFASRVPATGGAYSYLYAILGEFPAWLAG
                     WLTMMEFMTAISGVASGWAAYFKGLLSQYGIALPQALNGTFNPQAGTFVDLLPILVLV
                     LVTSLVLLNAKAALRFNSILVILKFSALALFVLVGIWNIKFDNWSNFAPYGFGQIYGA
                     STGIMAGASLMFFGFLGFESISMAVDEVKTPQKNIPRGIVLSLSIVTILYALVTLVLT
                     GVVHYSHLNVDDAVAFALRSVGISWAANYVSLVAILTLITVCISMTYALSRMIYSLAR
                     DGLVPAAFKELTKTSKVPKNATILTGLASAVAAGMFPLASIAAFLNICTLAYLIMLAY
                     GLIRLRKEKGMPKAGEFKTPLVPLLPILSIIICLSFMLQYNMNTWIAFLVALLVGSII
                     YFTYGYKHSTIEE"
     gene            4226..5143
                     /gene="adcAII"
                     /locus_tag="ACL29Z_001980"
     CDS             4226..5143
                     /gene="adcAII"
                     /locus_tag="ACL29Z_001980"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000744528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-binding lipoprotein AdcAII"
                     /protein_id="HGR0070230.1"
                     /translation="MKKQNLFLVLLSVFLLCLGACGQKESQTGKGMKIVTSFYPIYAM
                     VKEVSGDLNDVRMIQSSSGIHSFEPSANDIAAIYDSDVFVYHSHTLESWAGSLDPNLK
                     KSKVKVLEASEGMTLDRVPGLEDVEAGDGVDEKTLYDPHTWLDPEKAGEEAQIIADKL
                     SEVDSEHKETYQKNAQAFIKKAQELTKKFQPKFEKATQKTFVTQHTAFSYLAKRFGLN
                     QLGIAGISPEQEPSPRQLTEIQEFVKTYKVKTIFTENNASSKVAETLVKSTGVGLKTL
                     NPLESDPQNDKTYLENLEENMSILAEELK"
     gene            5151..>5524
                     /locus_tag="ACL29Z_001981"
     CDS             5151..>5524
                     /locus_tag="ACL29Z_001981"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000700331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal-type histidine triad protein"
                     /protein_id="HGR0070231.1"
                     /translation="MKINKKYLAGSVAVLALSVCSYELGRHQAGQVKKESNRVAYIDG
                     DQAGQKAENLTPDEVSKREGINAEQIVIKITDQGYVTSHGDHYHYYNGKVPYDAIISE
                     ELLMKDPNYQLKDSDIVNEIKGG"
BASE COUNT         1683 a          974 c         1173 g         1694 t
ORIGIN      
        1 gtaaaacgaa ataagaatag gacaaatcga tcaggacagt aaaatcgaat tctaacaatg
       61 ttttagaagt ccatatgtac tattctagtt tcaatatacc ataactgctc ctagtcaacc
      121 tgcaagtcct gtcccagctc caagctcagc tccgactcaa gatcctagag tggtagtaag
      181 cgcttcggct agctcaacga gcccacaagc tcaagagcaa gttgacaagt ctgaacttcg
      241 tgccttgagt caagagttag accaacactt gaaagctttg gcaacagtat ctgatccgaa
      301 aatcgatgca accaaggctg tcctcctaga tgctcaaaaa gctccggaag atagtgcctt
      361 gacagagtaa ggtctgcata ctgcagtaga gtctgtgaag gctgccttgg actctctcaa
      421 agatgtgaaa gcaaatgcta gcgacagcaa gcctgcacag gacaagaagg atgcaaaaca
      481 aggaacggaa gatagtaagg attcagataa gatgactgaa acaaactcag ttccggcagg
      541 agtgattgtg gtcagtctac ttgccctcct aggcgtgatt gccttctggc tgattcgccg
      601 taagaaagag tcagaaatcc agcaattaag cacggaatta atcaaggttc taggacagct
      661 agatgcagaa aaagcggata aaaaagtcct tgccaaagcc caaaaccttc tccaagaaac
      721 ccttgatttc gtgaaagaag aaaatggctc agcagagaca gaaactaaac tagtagagga
      781 gcttaaagca atccttgaca aactcaagta aaacatgatt tatgaaatgt cagacttaaa
      841 agacattttc gttcacaaaa gcagcgacga gtaatccttg tcgttgcttt ttggctattt
      901 tgggggataa gatccgcctt gactagcaaa agaaaagatt ggtccaatag tgcccgatac
      961 gattttgcgt agcagaaagc ttacaaataa aattgaatat agtaaaatag gattagaatt
     1021 attaagaaag ttggttcttt attggaaacg atagtatttt taatctctgt ttttctagca
     1081 ggtgttttat cctttttttc tccttgtatt tttcctcttc tgccagtcta tgctgggatt
     1141 ttattggatg atcaagaaag tgcaaaaagc ttttctttgt ttgggagaaa ggttctctgg
     1201 tcaggcttga ttcgaacact ttgctttatc gctggtatct ctctcatttt ctttattcta
     1261 ggctttggtg ctggttactt tggtcatatt ctctatgcaa attggtttcg atatggcatg
     1321 ggagctatta ttatcatttt gggtcttcat cagatggaaa tttttcattt gaagaaatta
     1381 gaagttcaaa aaagttttac ctttaaaaaa tcagattcta atcgttattg gtcagctttt
     1441 ttacttggta ttacctttag ctttggttgg acaccttgta ttggtccagt tttaagttct
     1501 gttttagcac ttgcggcttc tggaggcaat ggcgcttggc aaggagcgat ttatactctc
     1561 atttacactc tgggcatggc ccttcctttc ttggtattgg cactagcttc aggtctagtc
     1621 atgccatatt ttagtaaaat caagcgtcat atgatgctac taaagaaaat tggtggtttc
     1681 ctcattgttt taatgggaat tttgttacta ttaggacaag taaatgttct agctggaatt
     1741 tttgaataaa ggaggacaaa tgaaaaaagt aatgtttgct ggcttaagtc tcttgtcatt
     1801 agttgtattg atggcctgtg gtgaggaaga aactaaaaag actcaagcag cacaacagcc
     1861 aaaacaacaa acgactgtac aacaaattgc tgttggaaaa gatgctccag acttcacatt
     1921 gcaatccatg gatggcaaag aagttaagtt atctgatttt aagggtaaaa aggtttactt
     1981 gaagttttgg gcttcatggt gtggtccatg caagaaaagt atgccagagt tgatggaact
     2041 agcggcgaaa ccagatcgtg atttcgaaat tcttactgtc attgcaccag gaattcaagg
     2101 tgaaaaaact gttgagcaat tcccacaatg gttccaggaa caaggatata aggatatccc
     2161 agttctttat gataccaaag caaccacctt ccaagcttat caaattcgaa gcattcctac
     2221 agaatattta attgatagcc aaggaaagat tggaaagatt caatttggtg ctatcagtaa
     2281 tgcggatgca gaagcagcat ttaaagaaat gaactagaat cgataaaatc tgattacaag
     2341 atgtagtcag attttggtaa cttctaaaac taacttctag tttcccacaa cctagctttt
     2401 agtatgagaa aaacgtgtga caccagtgga aatccgtctt agactaactt ccactggttt
     2461 tctttttctt gatatataag ggttcaaaag cgaaaagact cagaaaaaag tgcacgacaa
     2521 atagccctaa aacagagtcg ttttagagta acttccagtt ttgggagaga gatggaagtt
     2581 actttgagaa gttacggtag tcagattttt ttagaaaaac attttataaa tattcacata
     2641 tctcctatat ttatggtaaa atagaatcat cagtttattt tggagtcaaa gatgaatata
     2701 tttagaacaa agaatgttag tttagataaa acagagatgc ataggcattt gaagttatgg
     2761 gatttgattt tgctgggtat tggagccatg gtagggacag gtgtctttac aatcacaggt
     2821 actgcagctg ctacacttgc tggtccagca ctagtgattt caatcgttat ttctgccttg
     2881 tgtgtgggat tatcagccct cttttttgca gaatttgcct cgcgagtacc cgctacagga
     2941 ggtgcctata gttacctcta tgctatctta ggagaattcc ctgcctggtt ggctggttgg
     3001 ttaaccatga tggagttcat gacagccata tcaggcgtag cttcgggttg ggcagcttat
     3061 tttaaaggct tgctctctca atacgggata gcccttcctc aggctttaaa tggtaccttt
     3121 aatcctcaag cagggacatt tgttgattta ttgcctattc ttgtcttggt cttggtgact
     3181 tcgcttgttt tactaaatgc caaggcagcc ttacgcttta attcgattct agttattttg
     3241 aaattttccg ctttagctct ctttgtttta gtaggaattt ggaatattaa gtttgataat
     3301 tggagcaatt ttgctcctta cggttttgga caaatctatg gagctagtac tggtattatg
     3361 gctggtgcgt ccttgatgtt cttcggtttt ttgggatttg aatccatctc tatggctgta
     3421 gatgaagtca agactcctca aaaaaatatt cctagaggga ttgtcttatc gctttctatc
     3481 gtaaccattc tctatgcctt ggtgaccctt gttttgactg gtgtggttca ctatagtcat
     3541 ttaaatgtcg atgatgccgt tgcctttgcc cttcgtagtg ttgggattag ttgggcagcc
     3601 aactatgtgt cattagtggc tatcttgacc ttgattacag tttgtatttc gatgacctat
     3661 gccctatcgc gtatgattta cagtttagca cgtgacggct tagtgcctgc tgcctttaag
     3721 gaactgacga agactagcaa ggtaccaaag aatgctacta tcttgacagg tctagcttca
     3781 gcagtagcag caggaatgtt cccactagcc agtattgcag cctttttaaa tatttgtacc
     3841 ttagcctact tgatcatgct ggcttatggt ctgattcgct tacggaaaga aaaaggaatg
     3901 cccaaagctg gggaatttaa aacaccattg gtacctctgt taccaatttt atcgatcatc
     3961 atttgtttat ccttcatgtt acagtataat atgaacacct ggattgcttt cctagttgcg
     4021 ttgttagtag gaagtattat ttacttcact tatggctata agcattctac catagaagaa
     4081 taaagtgaaa gtctattgag ttgttgacac tcagtagatt tttatatgtg aaagaaattt
     4141 caaatttttt ctaaaaatat cttgacagat taaattttca ggagtagaat atttactagt
     4201 taattaaatg gttaaggagt tgttcatgaa gaaacaaaat ttatttttag tcctgttaag
     4261 tgtctttctt ttgtgcttgg gggcttgtgg tcaaaaggaa agtcagacag gaaaggggat
     4321 gaaaattgtg accagttttt atcctatcta cgctatggtt aaggaagtat ctggtgactt
     4381 gaatgatgtt cggatgattc agtcaagtag tggtattcac tcctttgaac cttcggcaaa
     4441 tgatatcgca gccatctatg attcagatgt ctttgtttac cattctcata cactcgaatc
     4501 ttgggcagga agtctggatc caaatctaaa aaaatctaaa gtgaaggttt tagaggcttc
     4561 agagggaatg actttagacc gcgtccctgg actagaggat gtggaagcag gggatggagt
     4621 tgatgaaaaa acgctctatg accctcacac atggctagat cctgaaaaag ctggagaaga
     4681 agcccaaatt atcgctgata aactttcaga ggtggatagt gagcataaag agacttatca
     4741 aaaaaatgcg caagccttta tcaaaaaagc tcaggaattg actaagaaat tccaaccaaa
     4801 atttgaaaaa gcgactcaga aaacatttgt aacacaacat acagcctttt cttatctagc
     4861 gaagagattt gggcttaatc aacttggtat tgcaggtatc tctcctgaac aagaaccaag
     4921 tccacgacaa ctaacagaaa ttcaggaatt tgttaagacc tataaggtta aaacgatttt
     4981 tacagaaaat aacgcttctt caaaagtagc tgaaactctt gtcaaatcaa caggtgtggg
     5041 tcttaaaact ctgaatcctt tagagtcaga cccacaaaat gacaagacct atttagaaaa
     5101 tcttgaagaa aatatgagta ttctagcaga agaattaaag tgaggaaaga atgaaaatca
     5161 ataaaaaata tctagcaggt tcagtggcag tccttgccct aagtgtttgt tcctatgaac
     5221 ttggtcgtca ccaagctggt caggttaaga aagagtctaa tcgagttgct tatatagatg
     5281 gtgatcaggc tggtcaaaag gcagaaaatt tgacaccaga tgaagtcagt aagagagagg
     5341 ggatcaacgc cgaacaaatt gttatcaaga ttacggatca aggttatgtg acctctcatg
     5401 gagaccatta tcattactat aatggcaagg ttccttatga tgccatcatc agtgaagaac
     5461 ttctcatgaa agatccgaat tatcagttga aggattcaga cattgtcaat gaaatcaagg
     5521 gtgg
//
LOCUS       DBEJAU010000080         5520 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC323 isolate 683620
            SAMN38261939-rid24807223.denovo.080, whole genome shotgun sequence.
ACCESSION   DBEJAU010000080 DBEJAU010000000
VERSION     DBEJAU010000080.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261939
            Sequence Read Archive: SRR26833919
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 5520)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5520)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576303.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576303.1
            Genome Coverage       :: 154x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/19/2025 01:05:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,121
            CDSs (total)                      :: 2,078
            Genes (coding)                    :: 1,943
            CDSs (with protein)               :: 1,943
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 36
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 72 of 135
            Pseudo Genes (incomplete)         :: 63 of 135
            Pseudo Genes (internal stop)      :: 51 of 135
            Pseudo Genes (multiple problems)  :: 46 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5520
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261939-rid24807223.denovo.080"
                     /strain="GPSC323"
                     /isolate="683620"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            complement(162..1388)
                     /locus_tag="ACL29Z_001982"
     CDS             complement(162..1388)
                     /locus_tag="ACL29Z_001982"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000862399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HGR0070232.1"
                     /translation="MKVFLQNRDFRQLTINQWISTLGDTIFYLAFLNYVADASFAPLA
                     ILLITISETLPQVLQIFLGVLADFQHHRVLKYTVISFAKFLLYSIVSLSLSGQSFSLL
                     LVAFICLINLLSDTLSYFSGAMLTPIFIRIIGQDHLAEAIGFKQSTVSLVKTISNILG
                     GVLLGILSIQFISLLNALTFLIAFLGILFIKTDLLKVEKTISYQEGLSVKSFCQHLLQ
                     SSKLIWNMNKVLLVLFIISTSQAVINVTVPISTLFLRNQPFLNLQTGQSLALLATLEL
                     SALILGSLMSGYLQHTISIKIALYASLLLQLLLLVGFATAHFGLILIFSFLDAFFAGI
                     LSPRLQELVFKQIPEESMGAVQSSIGAITVVLPSLFTIALVTIATSFGTLAVSFVLLL
                     FLLVAFVMLLNIRESI"
     gene            complement(1460..2125)
                     /locus_tag="ACL29Z_001983"
     CDS             complement(1460..2125)
                     /locus_tag="ACL29Z_001983"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000720786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysostaphin resistance A-like protein"
                     /protein_id="HGR0070233.1"
                     /translation="MKKIISHRYFIIVFLLVIADQKFSVLVLRSDLVTGLSDFAYYLS
                     DMMLNFLVVLFALIAMIWSGKWQKINSRKFKGSYLFYSFLALLAFVVWNFVTFFLFPP
                     TRNEISYQHAAPTFTGATAFLMYFFYPVIAGPIFEEIIHRGLVMTALEKGKKWGLDVL
                     GSAVLFGVSHISNHGWVLTDFVFYMGGGLIFAVLFRMTKSIYWPIRLHIVYNGIGQLL
                     MLL"
     gene            complement(2137..2814)
                     /locus_tag="ACL29Z_001984"
     CDS             complement(2137..2814)
                     /locus_tag="ACL29Z_001984"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000738309.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysostaphin resistance A-like protein"
                     /protein_id="HGR0070234.1"
                     /translation="MKKMKEVKFHLATGLLILTYYLIFNVTSDLDFMVALSDNMYYVF
                     QVLLVLILGTIATIAFVKSEHWKECGRFQFRWSYLGVFLLSFFLLFVWANLTTYIFPR
                     TQNGSTVVEVATNLTGISYFVTRILYTSIIAPVSEEVVCRGLLMTSLSKVKRYYLDVL
                     VSAAIFGAMHVLQYGWITTDFIKYFGMGLIFCMMFRYTRSIYWAIALHASWNSFLLIV
                     TLLVFGY"
     gene            complement(2836..3042)
                     /locus_tag="ACL29Z_001985"
     CDS             complement(2836..3042)
                     /locus_tag="ACL29Z_001985"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000933479.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0070235.1"
                     /translation="MLNLQFAETMELTEAELQDVRGGNLVNSMGGGGRSGISGWGNQG
                     MSPNRGAFDWTIDLADGLFGRRRR"
     gene            complement(3328..4191)
                     /locus_tag="ACL29Z_001986"
     CDS             complement(3328..4191)
                     /locus_tag="ACL29Z_001986"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000572848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XRE/MutR family transcriptional regulator"
                     /protein_id="HGR0070236.1"
                     /translation="MIEKMELGEFYKELRLARKLKQSDVACDGLTASQLSKFELGQSM
                     LSADKFILAIQGINVTFDEFGHKLNNYQESPHMQIGRKVVDRFAHQDIAGLEQLLEEV
                     EQEQMAETYRRLNAIVIKDAIHSLDKSYPLAEEDSEFLTTYLYAIESWTWFELYLFCN
                     TLPFLSNQDLIFLSTSLLEKSKEFKELVHNRLYMKQGLLNIISELMERKLFSYIPIFE
                     AELESMLRPYDVFEKLLWQFLKKMSIFLQTKGSNQKEIEHFIQSLQVLENPQLIALFE
                     LRLQQYKKLID"
     gene            complement(4587..>5520)
                     /locus_tag="ACL29Z_001987"
     CDS             complement(4587..>5520)
                     /locus_tag="ACL29Z_001987"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001017606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016616 - oxidoreductase activity, acting
                     on the CH-OH group of donors, NAD or NADP as acceptor
                     [Evidence IEA];
                     GO_function: GO:0051287 - NAD binding [Evidence IEA];
                     GO_process: GO:0000271 - polysaccharide biosynthetic
                     process [Evidence IEA]"
                     /codon_start=2
                     /transl_table=11
                     /product="nucleotide sugar dehydrogenase"
                     /protein_id="HGR0070237.1"
                     /translation="IPTDYDEKIGSFNTYEIEQTVSKILRVKPNGKIILKSTVPIGFS
                     NKLKRLFDTKNIIFVPEFLREGCSIYDNLYPSRIVVGDETVEGRKIAELFLSISTHST
                     ANIKNVMLVSPTEAEAIKLFSNTFLALRVAFFNELDFFAERRSLNAEVVIKGVCLDPR
                     IGNFYNNPSFGFGGYCLPKDTKQLKKEFIEINAPVIEAIDISNTNRKQFIVKQILERK
                     PKIVGIYKLGMKYNSDNYKESAILSIINELLIVGIKILVYEPNLNVSIDNVIFEKNFE
                     LFTKQSDLIVANRWDRGLEAYKDKVYTRGIWIRD"
BASE COUNT         1920 a         1060 c          901 g         1639 t
ORIGIN      
        1 gaaagtaaaa ttaatttcta taaatgtttt agcaattgtt tcgtactatt ttagattcag
       61 tctactataa cacattcaga aaagagaaaa agtctgttga ttttgaccat cataaaaaga
      121 ctggcaatcc agtctcaaac atatattata gaaattctcc actaaatact ttcacgaata
      181 ttcagaagca tgacaaaggc aactagaaga aatagtaata aaacaaagct aactgccaga
      241 gttccaaagc tagtagcaat ggttaccaaa gctattgtaa ataagctagg taaaacaacc
      301 gtaatggcac cgatagaaga ttgaactgct cccattgact cctcaggtat ttgtttaaag
      361 acgagttctt gcaatctagg agagagaata cccgcgaaaa aggcatccaa aaagctaaag
      421 atcagaatca agccaaaatg agctgtcgca aagcccacta ggagtagtaa ttggagtagg
      481 agtgaagcat acagggctat ttttatggaa atggtatgtt gcagatagcc actcatcaga
      541 cttcccaaaa taagagctga caattctagt gtggctaaca aggcaagaga ttgacctgtt
      601 tgtaaattca aaaagggctg gtttcttaaa aatagagtgg aaataggaac cgtaacattt
      661 atcactgctt gactagtaga gataataaac aaaaccaaga gcaccttatt catattccat
      721 atcaatttcg atgattggag caaatgctgg caaaaggatt ttacagagag tccttcttga
      781 tagctaatcg ttttttctac tttcaagagg tcagttttta tgaagaggat acctaaaaat
      841 gcgattaaaa aggtaagagc gttcagtaag gaaataaact ggatggatag aatgcctagt
      901 aagactcctc ctaggatatt actgattgtt ttcactaaac taacagttga ctgtttaaag
      961 ccaatagctt ctgccagatg gtcttgccca ataattctaa tgaaaatcgg agtgagcatg
     1021 gcgcctgaaa aataactcaa tgtgtcagac aagaggttaa tcagacaaat aaatgctact
     1081 agcaacaagg agaaagactg ccctgaaagt gataaagaca ctatagagta aagcaaaaat
     1141 tttgcaaaac taatgactgt gtatttcaag acacgatgat gttgaaaatc cgccaaaact
     1201 cccagaaaga tttgtagaac ttggggcagg gtttctgaaa tcgtgatgag taaaatcgcc
     1261 aaaggggcaa aagatgcatc tgccacataa ttcaggaagg ccagataaaa aatcgtatcc
     1321 ccaagcgttg aaatccactg gttgatggtt aattgtctaa aatctctatt ttgaagaaat
     1381 actttcatca caactccttc ttaaattcaa atgggaagct ttccccaagg atagaccgcg
     1441 atactactaa caaccaaaat tacagtaaca tcaaaagctg accaatgcca ttgtagacta
     1501 tatgcagtct aataggccaa taaattgact ttgtcattct aaataagact gcaaatataa
     1561 gacctccacc catatagaag acaaagtctg tcaagaccca accgtgatta ctaatgtgcg
     1621 agaccccaaa taaaacagcg gaaccaagta catctagccc ccatttcttt cctttttcca
     1681 gagctgtcat caccaatccc cgatggatta tctcttcaaa aatgggacct gcaatcacag
     1741 gatagaaaaa atacatcaaa aatgctgtag cccctgtaaa agtcggagca gcatgttgat
     1801 aagaaatttc atttcgagta ggtgggaaaa gaaaaaaggt aacgaaattc caaacaacaa
     1861 aagcaagcag agctaggaag gaatagaaaa gataggatcc tttaaacttt ctactattga
     1921 ttttctgcca tttccccgac caaatcatag caataagagc aaataaaacc acaagaaaat
     1981 tcaacatcat atccgacaga taataggcaa agtcagatag cccagtaaca aggtcgctgc
     2041 gtaaaactag aacactgaac ttctggtcag caataactag tagaaaaact ataataaagt
     2101 agcggtgtga gattatcttt ttcatatatc accttgctaa tatccaaata ccaataaagt
     2161 aacaatgagt aagaaactat tccatgaagc atgcagagct atagcccaat agatggatcg
     2221 ggtgtagcga aacatcatac aaaatatcaa gcccattcca aaatacttta tgaaatctgt
     2281 cgttatccaa ccatactgca aaacatgcat agcgccaaat atggcagcgg aaacaagaac
     2341 atcaagatag tatctcttaa ctttagataa acttgtcatc aaaagaccac gacaaacaac
     2401 ctcttctgat acaggtgcga taatactagt ataaagtatt cgcgtaacaa aatagctaat
     2461 tcctgttaaa ttggtggcta cttctacgac tgtacttcca ttctgggtac gaggaaagat
     2521 ataggttgtt agatttgccc acacgaacaa taagaaaaaa gaaagaagga aaacacccag
     2581 gtaagaccaa cgaaactgga aacgaccaca ctctttccaa tgttcacttt tgacaaaagc
     2641 aattgtagct atagttccca gaataagtac caataaaact tggaacacat agtacatatt
     2701 atcagacaaa gcaaccataa aatctaagtc tgatgtgaca ttaaaaatga ggtaataagt
     2761 caaaatcaac aagccagttg ctaggtgaaa tttcacttct ttcattttct tcatcctatt
     2821 atctcctata agagcctatc ttctacggcg gccaaacaat ccatctgcta aatctatagt
     2881 ccaatcaaaa gctccacgat taggactcat cccttgattg ccccaaccag atataccact
     2941 tcttccacca cctcccatag aatttacgag gttgcctcct ctaacatctt gcaactcagc
     3001 ttctgtcaat tccattgttt ctgcaaattg taaatttaac atcttttaca ctccttcaat
     3061 tatcttcatt tgtaaaccac ttctgcaacc taggatttgc ttcaagtgct ttacaagtac
     3121 agtataacac gaaaattggc ttattttaga aaatcgcata tttgatattt tttcttatag
     3181 aaatttcaga tttgcgattt tggtgaattt gattacttct ctggtataat aaagttacta
     3241 ctaatgagga gtggagaaat atgaagaaac aaattttaac attattgaaa atcgttgctg
     3301 agattattat tattttgcca tttctaacta atcgataagc tttttgtatt gctgcaaacg
     3361 caattcaaaa agggctatta attgtggatt ttctaatact tgcagagatt ggataaagtg
     3421 ttcaatctct ttttgattgc ttcccttagt ttgaaggaaa atgctcatct tctttaaaaa
     3481 ctgccacaat aatttctcaa aaacatcgta tggacggagc atactctcca gctcggcttc
     3541 aaagattggg atataagaaa aaagtttgcg ctccatgagc tctgagatga tatttaagag
     3601 tccttgcttc atatacaatc gattgtgtac taactcttta aattctttgg atttttcgag
     3661 taaggaggtt gataaaaaga tcagatcttg attgctcaag aagggcagag tattgcaaaa
     3721 gagatagagt tcaaaccagg tccaagactc gatagcatag agataggtgg tcaaaaactc
     3781 gctatcctcc tctgctagtg ggtagctttt atctagtgag tggatggcat ctttgattac
     3841 aatagcattc aaacgacgat aagtctctgc catctgttct tgctcgactt cctccaacag
     3901 ttgctctaag ccagctatat cttgatgagc aaagcgatcc acaacctttc taccaatctg
     3961 catatgtgga gattcttgat agttgttgag cttgtgccca aactcatcaa aggtcacatt
     4021 aatcccttgg atggctaata tgaacttatc agcagacaac atggactgcc ctagctcaaa
     4081 cttggacaac tgagaagctg ttagcccgtc acaagccaca tctgactgct tgagctttct
     4141 cgccaaacgt aattccttgt aaaattcccc caattccatt ttttcaatca tcctaccacc
     4201 tcctagcttt tgcatattat atcattattt gtgttcattt gtcaaaatat tctgatagtt
     4261 agaaaaaata aaaaagccag ccttaagctg actctaaaag gaccgagcct tgtacaatac
     4321 agaactcaat cctcgttcta aatagaatgt ctaacttttt tgggcagtac acgagcttgg
     4381 ggaacagcca ctggaacgat gaggtgtgag ctcaaaatat cctccagtta tgtttttcct
     4441 aatagtatac cggaagaatg aaaggatttt ataatggagc ggttacaaag aacctacttt
     4501 ctattaaaca gtatactatg aaaatgtgaa aatttaacat ttttttgtac aaattttata
     4561 aattattgcc tttttaatat caatagttaa tctcttatcc agatccccct tgtgtaaact
     4621 ttatctttat aagcttcaag gcccctatcc catctatttg caacaattag atcactttgt
     4681 tttgtaaata gttcaaaatt cttttcaaaa attacgttat ctatactaac gtttaaattt
     4741 ggttcatata ctaaaatttt tataccgaca atcaatagtt cattaattat acttaaaata
     4801 gctgactctt tgtaattatc tgaattatat ttcatcccca atttatatat tcctactatc
     4861 tttggctttc gttccaatat ttgtttaact atgaactgtt ttctatttgt gtttgaaata
     4921 tcaatcgctt ctatcactgg ggcatttatt tctataaatt ctttttttaa ttgtttagta
     4981 tctttgggaa gacaatatcc tccaaatcca aaagaaggat tattataaaa atttccaatt
     5041 cttggatcta aacaaacacc ttttattaca acttcagcat ttaaacttct cctctcagca
     5101 aaaaaatcta gttcattaaa aaaagcaaca cggagagcta agaatgtgtt agaaaaaagc
     5161 ttaattgctt ctgcttcagt aggagaaact aacataacat ttttaatatt ggcagtacta
     5221 tgagtactaa tcgaaaggaa caactctgca atttttcttc cttcaactgt ctcatctcca
     5281 acaactatgc gacttggata taaattatca tatatagaac aaccttctct caaaaattca
     5341 gggacaaaaa tgatattttt tgtatcaaac agccttttta atttgtttga aaagccgatc
     5401 ggaactgttg actttaaaat aatctttcca ttaggtttta ccctcagaat cttcgatacc
     5461 gtttgttcga tttcatatgt attaaaacta ccaattttct catcataatc tgtcggaatc
//
LOCUS       DBEJAU010000081         5213 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC323 isolate 683620
            SAMN38261939-rid24807223.denovo.081, whole genome shotgun sequence.
ACCESSION   DBEJAU010000081 DBEJAU010000000
VERSION     DBEJAU010000081.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261939
            Sequence Read Archive: SRR26833919
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 5213)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5213)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576303.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576303.1
            Genome Coverage       :: 154x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/19/2025 01:05:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,121
            CDSs (total)                      :: 2,078
            Genes (coding)                    :: 1,943
            CDSs (with protein)               :: 1,943
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 36
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 72 of 135
            Pseudo Genes (incomplete)         :: 63 of 135
            Pseudo Genes (internal stop)      :: 51 of 135
            Pseudo Genes (multiple problems)  :: 46 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5213
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261939-rid24807223.denovo.081"
                     /strain="GPSC323"
                     /isolate="683620"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            complement(361..1089)
                     /locus_tag="ACL29Z_001988"
     CDS             complement(361..1089)
                     /locus_tag="ACL29Z_001988"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000105270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HGR0070238.1"
                     /translation="MSTKYLFIYNEIREKILCNKYTMNEQLPDEMTLAKQFACSRMTI
                     KKALDLLVSEGLIFRKRGQGTFVLSRGSSKRKLIVPERDIRGLTKISEDAHSTIDSRI
                     IHFKLEFANEFLAEKLQVALQSPVYNIYRLRIIDGKPYVLEQTYMSTDVIPGITEDIL
                     QKSIYNYIEGKLGLHIASATKILRASSSSENEQHYLQLLPTEPVFEVEQVAYLDNGTP
                     FEYSISRHRYDLFEFNSFALRHSS"
     gene            1247..2656
                     /locus_tag="ACL29Z_001989"
     CDS             1247..2656
                     /locus_tag="ACL29Z_001989"
                     /EC_number="3.2.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000728302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016798 - hydrolase activity, acting on
                     glycosyl bonds [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HGR0070239.1"
                     /translation="MKKKLVFPNLFWWGAASSGPQTEGQYGKVHENVMDYWFKTHPED
                     FFDNVGPLVASNFFHTYTEDFHLMKEIGVNSFRTSIQWSRLIKNLETGEPDPKGIAFY
                     NAIIEEAKKNQMDLVMNLHHFDLPVELLQKYGGWESKHVVELFVKFAKTAFTCFGDKV
                     HYWTTFNEPMVIPEAGYLYAFHYPNLKGKGKEAVQVIYNLNLASAKVIQLYRSLELDG
                     KIGIILNLTPAYPRSNSPEDLEASRFTDDFFNKVFLNPAVKGTFPERLVKQLERDGVL
                     WSHTEKELQLMKSNTVDFLGVNYYHPKRVQAQANPEEYQTPWMPDQYFKEYEWLERRM
                     NPYRGWEIFPKAIYDIAMIVKEEYGNIPWFISENGMGVENEARFIDENGVIDDVYRIE
                     FYEEHLRWLHKAIEEGSHCFGYHAWTAFDCWSWNNAYKNRYGFISVDLETQKRTIKSS
                     GRWYRKVSDNNGFEVEIEE"
     gene            2674..3969
                     /locus_tag="ACL29Z_001990"
     CDS             2674..3969
                     /locus_tag="ACL29Z_001990"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000798148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HGR0070240.1"
                     /translation="MKNSKFIDQFATFAGKLGNQIHLKTLRDAFVTVMPLYILAGLIV
                     LLNNTVFKWIFQGDTLTRFQYWGITIANGTLSISGMIIAVMVGYFLAKNRDFENPLAA
                     SMLSLVSLIVMMPNTVSVVPDGAKDAVNISGVLSFNNTGTGAMFAGVIVAIIATELFI
                     ELSNVKALQMNLGENIPPAVSRSFSVLLPVMTVISLFGVVSALLFNITGMNLISIITI
                     FIQEPIRHIGTSLIGVIIIYSLGNMLWLFGIHQAVIYSAILEPLLLINITENITAANN
                     GQAIPHIINLSQIQTFALMGGSGSTLCLLIATFLVSRNAVSKNVAKLSFGPGIFNINE
                     PVLFGYPIVYNISLAIPFITVPVLGILISYLATVTGFMSPAFIQVPWTTPVFLNAWLA
                     TAGDVRAVLVQFIIFALGVLLYIPFIKVNDKVVEQEMEG"
     gene            3974..4282
                     /locus_tag="ACL29Z_001991"
     CDS             3974..4282
                     /locus_tag="ACL29Z_001991"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HGR0070241.1"
                     /translation="MKQILLVCNAGMSTSMLVKKMQQSATERGIEISIQAKSMTEAKK
                     NIHEADVILIGPQIRYELLAVKEIAGNIPVDTIDMRDYGMMNGAKVLEQALAWIGEIR
                     "
     gene            4279..4587
                     /locus_tag="ACL29Z_001992"
     CDS             4279..4587
                     /locus_tag="ACL29Z_001992"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000134125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HGR0070242.1"
                     /translation="MTEEMEYICFQLIANSGAAKSSFIEAIQLAKAGNLKEAKIKVEE
                     AEDSLVEAHKIHSNLIQKEATGEKIGFSLLFMHAEDQMASTEIIQLLSKEFIDLYQNK
                     "
BASE COUNT         1752 a          875 c          949 g         1637 t
ORIGIN      
        1 ttgggagatt gaaattcatt tctagcaatt ttttagaagt cacagtctac tattctaacc
       61 tcaatatact atatgtgtta caagaaaaga ctcaaaaact tctcgtcagt gtaagaatgt
      121 ttgaaacact atttaaaact aaataactat aagaagtaga tcaggtgaac aatttcagta
      181 cctactctat aagctatacg aagatatttt tcaacatgat ggataaaacg atcactcttt
      241 taaagtcatc ttatttagaa aagagaaacc atttaagcat agatgggacc ttcttgccct
      301 gttttaaatt tttcttaaac tagagcctgt aaaagattgg cttcattttc acattttctc
      361 ctaggaggaa tgtcgtaatg caaaagaatt aaattcaaat aaatcatagc gatgacgact
      421 aatcgagtac tcaaacggag ttccgttatc caaataagcc acttgttcta cttcaaatac
      481 cggttccgtt ggaaggagct gcaagtaatg ttgctcattt tctgaactag aagaagctcg
      541 taagattttt gtagcactgg caatatgcaa tcctaacttt ccttcaatgt aattgtaaat
      601 cgatttttgt aaaatatctt cagtaatacc tggaataaca tcggtactca tataagtttg
      661 ttccagaaca taaggtttac cgtcaataat acgcaggcgg taaatattat aaactggact
      721 ctgcaaagcg acctgtagtt tttctgctaa aaattcattt gcaaattcta atttgaagtg
      781 aataatcctc gagtcaattg tagaatgagc atcttcagat atttttgtca gtccccggat
      841 atctctttct ggaacgatta attttctttt tgagctgcca cgagagagaa caaaggttcc
      901 ctgcccacgt tttctaaaaa ttaagccctc agaaactaac aagtctaaag cttttttgat
      961 cgtcattcga ctacaggcaa actgtttagc taatgtcatt tcatcaggca attgttcgtt
     1021 catggtatat ttattacaaa gaatcttttc acgaatctca ttgtaaataa ataaatattt
     1081 tgtactcatt taatctggtt ctctctataa tattctaata gtagtataac aaagttcaag
     1141 aaatgaggca aacacaagat atgtatcaac aatttttaaa aatgtctaga caaattttaa
     1201 aattatgcta tactttatgt atagaataat agaaaggagg ttgagcatga aaaaaaagtt
     1261 agtatttcct aatctgtttt ggtggggagc tgcttctagc ggacctcaga cagaaggtca
     1321 atatggaaaa gtacatgaaa atgtgatgga ctactggttc aaaacgcatc cagaagattt
     1381 tttcgataat gtcggacctc ttgtagccag taactttttt catacttaca ccgaagattt
     1441 ccacttgatg aaggaaattg gagttaattc tttccgcact tccatccaat ggagtcgact
     1501 catcaagaat ttagagacag gtgagcctga tccaaaaggt attgctttct acaatgccat
     1561 cattgaagaa gctaaaaaga accagatgga tcttgtgatg aatttacatc attttgattt
     1621 accagtggaa cttcttcaaa aatacggtgg ttgggaaagc aaacatgtag tggagttatt
     1681 cgtgaagttt gccaagactg ctttcacatg ctttggagat aaggttcatt actggacaac
     1741 tttcaatgag ccaatggtca ttccagaagc aggatactta tatgctttcc attatccaaa
     1801 tctaaaagga aagggaaaag aggccgtaca agtcatctat aatctaaacc ttgctagtgc
     1861 aaaagtgatt caactatatc gctcattaga acttgatgga aagattggga ttattttaaa
     1921 cttgacacct gcttatccaa gaagtaattc tccagaagac ttagaagcaa gtcgatttac
     1981 agatgacttc tttaacaaag tcttcttgaa tccagctgtt aaaggaactt tcccagaaag
     2041 attggtaaaa cagctagaga gagatggcgt gttatggagt cataccgaaa aagagcttca
     2101 actgatgaaa tcaaatacgg ttgattttct tggagtaaac tactaccatc caaaacgtgt
     2161 tcaagcacaa gcaaatcctg aggaatatca gacgccctgg atgccagacc aatacttcaa
     2221 agagtatgaa tggctggagc gtcgcatgaa tccatatcgt ggttgggaaa tttttccgaa
     2281 agccatttat gatattgcta tgattgtgaa ggaagaatat ggtaatatcc catggtttat
     2341 cagtgaaaac ggaatgggtg ttgaaaacga agcacggttt atcgatgaaa atggagttat
     2401 cgatgacgtg tatcgtattg aattttatga agaacattta agatggctac ataaagccat
     2461 tgaagaggga agtcactgtt ttggatacca cgcttggacc gcatttgatt gctggtcttg
     2521 gaataatgca tataagaatc gttacggatt tatctccgtt gatttagaaa cgcaaaagag
     2581 aaccatcaag agctcaggaa gatggtatcg caaagtaagt gacaataacg gttttgaagt
     2641 agaaattgag gagtaaagag aggagatatt catatgaaaa actcaaaatt tatagaccaa
     2701 tttgccacct ttgctggtaa actagggaac caaattcatt taaaaaccct aagagatgca
     2761 ttcgtaacag taatgccatt atatattttg gcaggtttaa tcgttctttt gaacaacacg
     2821 gtatttaagt ggattttcca aggggataca ttaacaagat tccaatattg gggaataaca
     2881 attgcaaacg gtactttaag tatttcaggt atgattattg ctgtaatggt tggttatttc
     2941 ttagctaaaa acagagattt cgaaaacccg ttagcagcat caatgctatc attagtttct
     3001 ttaattgtga tgatgccaaa tacagtttct gtagttcctg acggagcaaa agatgctgta
     3061 aacatttcag gtgttctttc attcaacaac acaggtacag gcgcaatgtt cgccggggtt
     3121 atcgtagcga ttattgcaac agaattattc attgaattat caaatgttaa agctttacaa
     3181 atgaaccttg gtgaaaatat tccaccagct gttagtagat catttagcgt attacttcca
     3241 gtcatgaccg tcatctcctt atttggggtt gtttcagcat tattgttcaa tataactgga
     3301 atgaacttaa tctcaatcat tacaatcttt attcaagaac caattcgtca tattggtaca
     3361 agcttaatcg gggtcattat tatttactct ttaggaaata tgttatggct atttggtatt
     3421 caccaagcag ttatttacag tgccatctta gaaccattac tattaattaa cattactgaa
     3481 aacatcactg cagcaaataa tggacaagcc attccacaca tcatcaactt atcacaaata
     3541 caaacattcg ctttaatggg tggtagtgga tctacattat gtttattaat agcaacattc
     3601 ttagtgagtc gcaatgctgt ctctaaaaac gtggctaaat tatcttttgg acctggtatc
     3661 ttcaatatca atgaaccagt attattcggt tacccaatcg tttataacat ttcattagct
     3721 attccattta tcacagttcc agtccttggt attttaatca gctacttagc aacagttaca
     3781 ggattcatga gtcctgcatt tatacaagtt ccttggacta caccagtatt cttaaatgca
     3841 tggttagcaa cagcagggga cgtgagagca gttctagttc aattcatcat ctttgcactt
     3901 ggagttcttc tatacattcc atttatcaaa gttaatgaca aagttgttga acaagaaatg
     3961 gaaggttaag attatgaaac aaattttatt agtatgtaat gcgggaatgt cgacaagtat
     4021 gcttgttaaa aaaatgcaac aaagtgcgac tgaacgtggg attgaaattt ctatccaagc
     4081 aaaatcaatg acagaagcga aaaagaatat ccatgaagca gatgtcattc taattgggcc
     4141 acaaattcgt tatgagttac ttgctgtgaa agaaattgca ggaaatatcc ctgtagatac
     4201 cattgatatg cgggattacg gaatgatgaa tggagcaaaa gttctggaac aagcacttgc
     4261 atggatagga gaaataagat gacagaagaa atggaatata tctgttttca gctcattgcc
     4321 aatagtggag cagccaaatc atcctttatt gaagccatcc aactagctaa ggcaggaaat
     4381 ttaaaagaag cgaaaattaa agttgaagaa gcggaagact ccttagtaga agcgcacaag
     4441 attcactcta atctcataca aaaagaagct actggagaaa aaataggatt ctccttgcta
     4501 tttatgcatg cagaagacca aatggcttca acagagatta ttcagttgct atctaaagaa
     4561 ttcatcgatc tctatcaaaa taaataggaa cactgtcatt cccatctgtc tttattaatg
     4621 acgactacat tgtaggaacc tccaaaagtt ggacaaaatg attgaaagga ttggatcctg
     4681 cattacacaa gatccaatcc ttttctttta ctctagtttt tataatatgt tgaatctaga
     4741 atagtccact gtagtttcta aaaaattgct ggaaatggat gttaagctcc aatttatttg
     4801 tttatatctt atttcagttt actatactag cttattattc tagtgaaaaa ttgaatgagc
     4861 cactatttat ttaatatgta tgatgaggga atgactcaaa aacttcttgt cgatataaga
     4921 atatctgaga tagtatttta aaacgaaagg actataaaag ctcatttcct tcgcacttat
     4981 tttatagaga tctatcatta tactctttag aaatcaaaaa gcaacacacc ttgtcatcgt
     5041 tttatcgtaa atctgttaat gagggggcta gtcttatctg caatctcaaa tcagtgtttt
     5101 gagctgaatg gcactcgttt tctagtttgc tctttgattt taattgggcc ttagtaaata
     5161 ctactcttaa attaaactat agtgaattga aataagatgt gaacaactct atc
//
LOCUS       DBEJAU010000082         5134 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC323 isolate 683620
            SAMN38261939-rid24807223.denovo.082, whole genome shotgun sequence.
ACCESSION   DBEJAU010000082 DBEJAU010000000
VERSION     DBEJAU010000082.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261939
            Sequence Read Archive: SRR26833919
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 5134)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5134)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576303.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576303.1
            Genome Coverage       :: 154x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/19/2025 01:05:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,121
            CDSs (total)                      :: 2,078
            Genes (coding)                    :: 1,943
            CDSs (with protein)               :: 1,943
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 36
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 72 of 135
            Pseudo Genes (incomplete)         :: 63 of 135
            Pseudo Genes (internal stop)      :: 51 of 135
            Pseudo Genes (multiple problems)  :: 46 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5134
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261939-rid24807223.denovo.082"
                     /strain="GPSC323"
                     /isolate="683620"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            1..508
                     /locus_tag="ACL29Z_001993"
                     /pseudo
     CDS             1..508
                     /locus_tag="ACL29Z_001993"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001841243.1"
                     /note="frameshifted; incomplete; missing N-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=3
                     /transl_table=11
                     /product="IS110 family transposase"
     gene            complement(809..2698)
                     /locus_tag="ACL29Z_001994"
     CDS             complement(809..2698)
                     /locus_tag="ACL29Z_001994"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000750662.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2207 domain-containing protein"
                     /protein_id="HGR0070243.1"
                     /translation="MKKTFFLLVLGLFCLLPLSVFAIDFKINSYQGDLYIHADNTAEF
                     RQKIVYQFEEDFKGQIVGLGRAGKMPSGFDIDPHPKVQAAKNGAELADVTSEVTEEAD
                     GYTVRVYNPGQEGDIVEVDLVWNLKNLLFLYDDIAELNWQPLTDSSESIEKFEFHVRG
                     DKGAEKLFFHTGKLFREGTIEKSNLDYTIHLDNLPAKRGVELHAYWPRTDFASARDQG
                     LKGNRLEEFNKIEDSIVREKDQSKQLVTWVLPSILSISLLLSVCFYFIYRRKTTPSVK
                     YAKNHRLYEPPMELEPMVLSEAVYSTSLEEVSPLVKGAGKFTFDQLIQATLLDVIDRG
                     NVSIISEGDAVGLRLVKEDGLSSFEKDCLNLAFSGKKEETLSNLFADYKVSDSLYRRA
                     KVSDEKRIQARGLQLKSSFEEVLNQMQEGVRKRVSFWGLPDYYRPLTGGEKALQVGMG
                     ALTILPLFIGFGLFLYSLDVHGYLYLPLPILGFLGLVLSVFYYWKLRLDNRDGVLNEA
                     GAEVYYLWTSFENMLREIARLDQAELESIVVWNRLLVYATLFGYADKVSHLMKVHQIQ
                     VENPDINLYVAYGWHSTFYHSTAQMSHYASVANTASTYSVSSGSGSSGGGFSGGGGGG
                     SIGAF"
     gene            2836..4401
                     /locus_tag="ACL29Z_001995"
     CDS             2836..4401
                     /locus_tag="ACL29Z_001995"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001227294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding
                     protein/permease"
                     /protein_id="HGR0070244.1"
                     /translation="MRKIYLSIFTSLLLMLGLVNVAQADEYLRIGMEAAYAPFNWTQD
                     DDSNGAVKIDGTNQYANGYDVQIAKKIAKDLGKEPLVVKTKWEGLVPALTSGKIDMII
                     AGMSPTAERKQEIAFSSSYYTSEPVLLVKKDSAYASAKSLDDFNGAKITSQQGVYLYD
                     LIAQIPGAKKETAMGDFAQMRQALEAGVIDAYVSERPEALTAEAANSKFKMIQVEPGF
                     KTGEEDTAIAIGLRKNDNRISQINASIETISKDDQVALMDRMIKEQPAEATTTEETSS
                     SFFSQVAKILSENWQQLLRGAGITLLISIVGTIIGLIIGLAIGVFRTAPLSENKAIYG
                     LQKLVGWVLNVYIEIFRGTPMIVQSMVIYYGTAQAFGINLDRTLAAIFIVSINTGAYM
                     TEIVRGGILAVDKGQFEAATALGMTHNQTMRKIVLPQVVRNILPATGNEFVINIKDTS
                     VLNVISVVELYFSGNTVATQTYQYFQTFTIIAVIYFVLTFTVTRILRFIERRMDMDTY
                     TTGANQMQTEDLK"
     gene            4401..>5134
                     /locus_tag="ACL29Z_001996"
     CDS             4401..>5134
                     /locus_tag="ACL29Z_001996"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000189492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HGR0070245.1"
                     /translation="MTQAILEIKHLKKSYGQNEVLKDISLTVHKGEVISIIGSSGSGK
                     STFLRSINLLETPTDGQILYHGQNVLEKGYDLTQYREKLGMVFQSFNLFENLNVLENT
                     IIAQTTVLKRERTEAEEIAKENLEKVGMGERYWQAKPKQLSGGQKQRVAIARALSMNP
                     DAILFDEPTSALDPEMVGEVLKIMQDLAQEGLTMIVVTHEMEFARDVSHRVIFMDKGV
                     IAEEGKPEDLFTNPKEDRTKEFLQRYL"
BASE COUNT         1572 a         1181 c          961 g         1420 t
ORIGIN      
        1 atacctacca actcttgaca cgctacccta atcctcagaa aaggattgag gcaggatttg
       61 ataagctgat agaaattaag cgattgaccg cttctaaaat tcaggatatc ctctcagtcg
      121 cacctcgttc tatcggaaca acatctcctg ctcgtgaatt cgaaatcatc aagcattaca
      181 agaggctcat tgacaaggcg gaaacatgta tcaatgactc gatggctgag ttcaactcgg
      241 tcatcacgac ggttactggg attggggatc gtttagggcg gtcattttag ccgagattcg
      301 aaatattcat gcctttgata atcctgctca attacaagct ttcgctggac tggattcttc
      361 tatttatcag tcaggtcaga ttgatttagc tggaagaatg gtcaaacggg gttcccctca
      421 tctgcggtgg gcactcatac aagctgccaa agcatgccct cgcttttcac ctgcttctaa
      481 ggcctatctt aagactaagt tagaataagg aaaacattac aatgtagcca tcatccacct
      541 tgcaaaaaaa cttatccgaa ccctgtttta tatcctaaaa aagagctgcc atttgacgaa
      601 caaaaagtga tgtaatttct gaaattaaca caggattacc tttgaaaaaa tggacttttt
      661 caagggcttt ttgccgtgct ctaaaatcat cgccaaatca tcaaattgaa ataagaaata
      721 gtttagataa aactattgac ttttcttata gtttgtcttt tttctatctt ccattatatc
      781 atactttttc agtctatggt agctctcttt aaaaggcacc gatactgccg ccacctccgc
      841 ctccagagaa gccaccacca gaacttccac ttccagaaga tacagagtag gtgcttgctg
      901 tatttgcgac actagcataa tggctcattt gtgctgttga atgataaaac gtactgtgcc
      961 agccataagc tacatagaga ttgatatctg gattttccac ttgaatctga tgaaccttca
     1021 tcaaatgact aaccttgtcc gcatagccaa ataaggtcgc atagaccaag aggcgattcc
     1081 agaccacaat actttccagt tcagcctgat ccaatcgtgc aatctcacgc aacatatttt
     1141 caaaactggt ccagagatag tagacctcag ctcccgcttc atttagaaca ccatcacgat
     1201 tatctagtcg aagcttccaa taatagaaaa cagacaaaac taaccctaga aaaccaagta
     1261 ttggcaaagg gaggtaaaga tagccatgaa cgtctaaact gtacaagaac aaaccaaatc
     1321 cgataaatag gggcaggata gtcaaggcac ccatacccac ttgcaaggcc ttttccccac
     1381 cagttaaagg acgataataa tctgggagcc cccagaagga aactcgtttt ctcactcctt
     1441 cttgcatctg gttcaatacc tcttcaaaag aagatttgag ttgaagccct cttgcttgaa
     1501 tccgtttttc atcagaaact ttggctctac gataaagact atcagatacc ttgtaatccg
     1561 caaacaaatt ggaaagagtt tcttcttttt tacctgaaaa agctagattt aggcagtctt
     1621 tctcaaagct tgacaaacca tcttctttta ctagcctcaa accaactgca tctccttctg
     1681 aaatgataga gacattccca cggtctatca catctagcaa ggtagcttga ataagttgat
     1741 caaaggtgaa ttttccagct cccttgacca agggactcac ttcctccaag gaggtcgagt
     1801 agactgcttc tgataaaacc ataggctcta attccattgg tggttcatag agacgatgat
     1861 ttttggcata tttgactgaa ggagtggtct ttcttctata aataaaatag aagcagacac
     1921 tcaataacaa ggagatagaa agtatcgaag ggaggaccca agtaacgagt tgtttactct
     1981 gatctttttc tctaacaatc gagtcttcta tcttattaaa ctcttctaaa cgattccctt
     2041 tcaatccctg atccctagcg ctagcaaaat cggtccgagg ccaataggca tgcaactcaa
     2101 ctccacgctt agccggaaga ttgtctaaat ggatagtata atcaaggtta ctcttttcaa
     2161 tcgttccctc tctaaaaagt ttccctgtat ggaaaaagag tttttcagcc cccttgtctc
     2221 cccttacatg aaattcaaac ttttcaatag actctgaact atctgtcaga ggttgccaat
     2281 ttaattcagc gatatcatca taaaggaaaa gtaaattttt taagttccag acgaggtcaa
     2341 cttcaactat gtcgccctcc tgacctggat tatagactct cacagtataa ccatccgctt
     2401 cttctgttac ttcgctagtc acatctgcta gttctgcacc gtttttcgcg gcctgaacct
     2461 ttggatgagg gtcaatgtca aacccgctag gcatcttacc agcacgtcca agtcccacga
     2521 tttggccctt aaagtcctcc tcaaactggt aaactatctt ctgtctaaac tctgccgtat
     2581 tatctgcatg aatatacaaa tccccttgat aagagtttat cttgaaatca atggcaaaaa
     2641 cagagagtgg aagaaggcaa aacaagccta acaccagtaa gaaaaaagtt tttttcatca
     2701 actaagcccc ctttttatct ttcttatcat tatagcattt tttcgtaagt aaaggcttac
     2761 ttatgttgaa aaattacgca tttttcgata aaataggaga cagttatttt ttaatagatc
     2821 agaataggag aaatcatgag aaaaatatac ttatctattt tcacaagtct cttgctgatg
     2881 ctaggacttg tcaatgttgc tcaagccgat gaatatttac gcatcgggat ggaagcagca
     2941 tatgctccct ttaactggac ccaggatgat gatagcaacg gagctgtcaa aatcgatggg
     3001 accaatcagt atgccaacgg atacgatgtt caaatcgcca agaaaatcgc taaggactta
     3061 ggtaaagaac ctttggttgt taaaaccaag tgggaaggtc tagtccctgc ccttacttct
     3121 ggtaagattg acatgattat cgcaggtatg agtccaactg cagaacgcaa acaagaaatt
     3181 gccttttcga gcagttacta cactagcgaa ccagttttgc ttgtcaaaaa agattctgcc
     3241 tacgcaagtg ctaaatcttt ggatgacttt aacggtgcaa aaatcacttc tcaacaaggg
     3301 gtctacctct acgacttgat tgcacaaatc ccaggtgcta aaaaagaaac agccatggga
     3361 gacttcgctc aaatgcgaca agctcttgag gctggtgtca ttgatgctta tgtttccgaa
     3421 cgtccagaag cactgactgc tgaagctgcg aactctaagt tcaagatgat tcaagtagaa
     3481 cctggtttca aaactgggga agaagataca gctatcgcta tcgggcttcg taaaaatgac
     3541 aatcgtatta gccaaatcaa tgccagcatt gaaaccattt caaaggacga ccaagttgcc
     3601 ctgatggatc gtatgatcaa ggaacaacct gccgaagcta caacaactga agagactagc
     3661 agtagtttct ttagccaagt cgctaaaatt ctttctgaaa actggcaaca actcttgcgt
     3721 ggtgctggta tcactctttt aatctctatc gtcggaacca tcataggtct cattattgga
     3781 cttgccattg gtgtcttccg tactgctcct ctctctgaaa acaaagccat ttatggcctt
     3841 caaaaactag tcggctgggt tctcaatgtc tacattgaaa ttttccgtgg tacgccaatg
     3901 attgttcaat cgatggttat ctactatgga actgcccaag ctttcgggat caaccttgac
     3961 cgtacactgg ctgctatctt catcgtttca atcaataccg gtgcctacat gactgaaatc
     4021 gtccgtggtg gtatcctagc agttgacaag ggacaatttg aagctgcgac tgctcttggt
     4081 atgacccata accagaccat gcgtaagatt gtcctacctc aggtagtccg taacatccta
     4141 cctgcaactg gtaatgaatt tgtcatcaat atcaaagata catctgtatt gaacgttatc
     4201 tctgttgtcg aactttattt ctcaggaaat accgtggcaa cacaaaccta tcaatacttc
     4261 cagacattta caatcatcgc cgtgatttac tttgtcctca ccttcaccgt aacacgtatc
     4321 ctacgcttta tcgagcgcag aatggacatg gatacctata ctacaggtgc taaccaaatg
     4381 caaacggagg atttgaaata atgacacaag caatccttga aattaaacac ctcaaaaaat
     4441 cctatggaca aaacgaagtg ctaaaagaca tttctctcac tgtccacaag ggagaagtta
     4501 tctctatcat cggaagctct ggaagtggga aatcgacctt cctacgctcc attaacctac
     4561 ttgaaacgcc aactgatgga caaatccttt atcatggaca aaacgtcctg gaaaaaggct
     4621 atgacctcac gcaataccgt gaaaagttag gaatggtttt ccaatccttt aacctctttg
     4681 aaaatctcaa cgttcttgaa aacacaatca tcgctcagac aactgtcctt aaacgcgaac
     4741 gcacagaagc tgaagaaatt gccaaagaga acctggaaaa ggtcggcatg ggagaacgct
     4801 actggcaagc gaaacccaaa caactctcag gtggtcaaaa acaacgtgtg gccatcgctc
     4861 gtgccctttc aatgaatcct gacgccattc tctttgatga accaacatca gctctcgatc
     4921 cagaaatggt tggagaggtc ctcaaaatca tgcaggacct ggctcaggaa ggcttgacca
     4981 tgattgtcgt aacccatgaa atggaatttg cccgtgatgt ctctcaccgt gttatcttta
     5041 tggataaggg tgtgattgct gaagaaggta aaccagaaga cctcttcact aatcctaaag
     5101 aagaccgtac aaaagaattc cttcaacgtt atct
//
LOCUS       DBEJAU010000083         4431 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC323 isolate 683620
            SAMN38261939-rid24807223.denovo.083, whole genome shotgun sequence.
ACCESSION   DBEJAU010000083 DBEJAU010000000
VERSION     DBEJAU010000083.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261939
            Sequence Read Archive: SRR26833919
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 4431)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4431)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576303.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576303.1
            Genome Coverage       :: 154x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/19/2025 01:05:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,121
            CDSs (total)                      :: 2,078
            Genes (coding)                    :: 1,943
            CDSs (with protein)               :: 1,943
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 36
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 72 of 135
            Pseudo Genes (incomplete)         :: 63 of 135
            Pseudo Genes (internal stop)      :: 51 of 135
            Pseudo Genes (multiple problems)  :: 46 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4431
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261939-rid24807223.denovo.083"
                     /strain="GPSC323"
                     /isolate="683620"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            84..1109
                     /locus_tag="ACL29Z_001997"
     CDS             84..1109
                     /locus_tag="ACL29Z_001997"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000790748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0015891 - siderophore transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="iron-siderophore ABC transporter
                     substrate-binding protein"
                     /protein_id="HGR0070246.1"
                     /translation="MKNKFFLIAILAMCIVFSACSSNSVKNEENTSKEHAPDKIVLDH
                     AFGQTILDKKPERVATIAWGNHDVALALGIVPVGFSKANYGVSADKGVLPWTEEKIKE
                     LNGKANLFDDLDGLNFEAISNSKPDVILAGYSGITKEDYDTLSKIAPVAAYKSKPWQT
                     LWRDMIKIDSKALGMEKEGDELIKNTEARISKELEKHPEIKGKIKGKKVLFTMINAAD
                     TSKFWIYTSKDPRANYLTDLGLVFPESLKEFESEDSFAKEISAEEANKINDADVIITY
                     GDDKTLEALQKDPLLGKINAIKNGAVAVIPDNTPLAASCTPTPLSINYTIEEYLNLLG
                     NACKNAK"
     gene            1099..2106
                     /locus_tag="ACL29Z_001998"
     CDS             1099..2106
                     /locus_tag="ACL29Z_001998"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001244688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FecCD family ABC transporter permease"
                     /protein_id="HGR0070247.1"
                     /translation="MRNKKQINLGIIFVICLGLLITIFLSLKLGTKEINIRDFLAAFG
                     MGNTNDDFIKSIIYKRIPRTIFAILAGSSLAISGVLMQSVTRNPIADPGILGINTGAS
                     LSVVIGLSFLGISSSISHISFAIIGGLVSAIFVYAIAVSGKAGLTPIKLALSGTCVSM
                     ALSSFVSFLILPNNNVLDKFRFWQIGSLGAATLSSISTLLPFIILGHLIAIFISSDLN
                     ALAMGDEMAVGLGVNVNRIRSLAIIASVLLCSSITAIGGPIGFVGLIVPHFCGLFISK
                     DIRTMTISSSFIGAELLLICDIIGRMLGKPGEIEVGIITAIIGGPVLIYVTMKNRGVN
                     N"
     gene            2106..3113
                     /locus_tag="ACL29Z_001999"
     CDS             2106..3113
                     /locus_tag="ACL29Z_001999"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001180354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
                     /protein_id="HGR0070248.1"
                     /translation="MQNLIIGIQKRKNRITLFSSLFLLIIISLSFFILLIGDESYSFS
                     TLIKVLNSETVPGASFSIMEIRLPKLLAGIIAGWSFGLAGFIFQTMLRNPLASPDIIG
                     VTSSSSIAAVFCILVLKTNSLTTGIISITCGLTSSLILFLLAKKDGFSAARLIILGIG
                     FQAVTRAGTSFLLLKVARYELQEVMRWLSGSLSFTKLDDIPLVLIVSIIATILVLFFN
                     KRLEIIELGEEIAIGLGANPELSRLVLIFCAVSLTAFSTSITGPIACISFLAGPIALN
                     IGKKRSPILAGLVGILLVLLSDIFSQNILPARYPVGVVTGLLGSPYLIYLLIKMNRRN
                     I"
     gene            3113..3907
                     /locus_tag="ACL29Z_002000"
     CDS             3113..3907
                     /locus_tag="ACL29Z_002000"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000677523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGR0070249.1"
                     /translation="MKGLWSNNLTCGYDEKIILENINIKIPEEKISVIIGSNGCGKST
                     LIKTLSRLIKPLEGEVLLDNKSINSYKEKDLAKHIAILPQSPIIPESITVADLVSRGR
                     FPYRKPFKSLGKDDLEIINRSMVKANVEDLANNLVEELSGGQRQRVWIALALAQDTSI
                     LLLDEPTTYLDISYQIELLDLLTDLNQKYKTTICMILHDINLTARYADYLFAIKEGKL
                     VAEGKPEDILNDKLVKDIFNLEAKIIRDPISNSPLMIPIGKHHVSS"
     gene            4058..4242
                     /locus_tag="ACL29Z_002001"
                     /pseudo
     CDS             4058..4242
                     /locus_tag="ACL29Z_002001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076612340.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus and C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
BASE COUNT         1605 a          644 c          749 g         1433 t
ORIGIN      
        1 tattattaaa tttgtaactg tatctattga caatgataat tattatcgat acaatagact
       61 tgaaatatgt ttaaggagtt tttatgaaaa acaaattttt tctaatagct attttagcta
      121 tgtgtatagt ttttagcgct tgttcttcta attctgttaa aaatgaagaa aatacttcta
      181 aagagcatgc gcctgataaa atagttttag atcatgcttt cggtcaaact atattagata
      241 aaaaacctga aagagttgca actattgctt ggggaaatca tgatgtagca ttagctttag
      301 gaatagttcc tgttggattt tcaaaagcaa attacggtgt aagtgctgat aaaggagttt
      361 taccatggac agaagaaaaa atcaaagaac taaatggtaa agctaaccta tttgacgatt
      421 tggatggact taactttgaa gcaatatcaa attctaaacc agatgttatc ttagcaggtt
      481 attctggtat aactaaagaa gattatgaca ctctatcaaa aattgctcct gtagcagcat
      541 acaaatctaa accttggcaa actttatgga gagatatgat taaaattgat tcaaaagcct
      601 taggtatgga aaaagaaggt gatgagttaa tcaaaaatac tgaagctcgt atatccaaag
      661 aattagaaaa acatccagaa atcaaaggaa aaatcaaagg aaaaaaagta ttatttacta
      721 tgattaatgc tgcagataca tcaaaattct ggatttatac tagcaaagat ccaagagcaa
      781 attatttaac agatttaggt ctagttttcc ctgaatcatt aaaagaattt gagagtgaag
      841 atagttttgc aaaggaaatt tctgcagaag aagcaaataa gataaatgat gctgatgtaa
      901 tcataactta tggtgatgat aaaactcttg aagctttaca aaaagatcct cttttaggta
      961 aaataaatgc aattaaaaat ggtgccgttg ctgtaattcc agataataca ccgttagcag
     1021 cctcatgcac tccaacacca ctttcaataa actatactat tgaagaatac ctaaatcttt
     1081 taggaaatgc atgcaaaaat gcgaaataaa aaacaaataa acctaggcat aatttttgta
     1141 atctgcctag gtcttcttat tacaatattt ttgtcattaa agcttggaac aaaagaaatt
     1201 aatatcagag attttttagc agcttttgga atgggcaata caaatgatga ttttattaaa
     1261 tcaattatat ataaaagaat acctagaact atttttgcaa ttttagcagg ttctagtctt
     1321 gccataagcg gtgtattgat gcaatcagtt actagaaacc caatagctga tccaggtata
     1381 ctcggtataa acacaggagc aagtcttagt gtagtaattg gtctttcttt tttaggaatt
     1441 tcatcaagca taagccatat aagttttgca atcattggtg gcttagtaag tgcaattttt
     1501 gtatacgcga ttgctgtaag cggaaaagca ggccttaccc ctataaaact tgccttatca
     1561 ggaacttgtg ttagtatggc tttaagcagt tttgtaagtt ttttaatttt accgaataat
     1621 aacgtcttag acaaatttag attttggcaa ataggtagcc ttggagcagc tacattatct
     1681 tctatatcta cactactacc ttttataatt ttaggtcact tgatagctat atttatttca
     1741 tcagatttaa acgctttagc tatgggtgat gaaatggctg ttggtcttgg agttaatgtt
     1801 aataggataa gatcacttgc aataattgca agtgtgcttt tatgttcaag tattactgca
     1861 attggtggac ctattggctt cgtaggtctt atagttcctc acttttgtgg cttatttata
     1921 agcaaagata tacgcacaat gaccatttct tcatctttta taggtgcaga gctcttgctt
     1981 atatgtgata taatcggccg tatgttaggt aaaccaggtg aaattgaagt agggataatt
     2041 actgcaataa tcgggggtcc agtacttatt tatgtaacta tgaaaaatag aggggttaat
     2101 aactaatgca aaatttaatt ataggtattc aaaaaagaaa aaatagaata acactatttt
     2161 cctcactatt tttattaata ataatcagtc tatcattttt cattttactt atcggagatg
     2221 aaagttattc tttttcaact ttgattaaag tcttaaatag tgaaactgtt cctggagcta
     2281 gtttttcgat tatggaaatt agattaccaa aattattagc aggaattata gctggctggt
     2341 cttttggatt ggcaggattt atctttcaaa ctatgttaag aaatcctctt gcaagtcctg
     2401 atataatcgg tgtcacaagt tcttcatcta ttgcagcggt cttttgcata ttggtattaa
     2461 aaacaaatag tttaactact ggaattattt caataacttg tggactaaca tcatctttaa
     2521 tattattttt actagctaaa aaagatggtt tttcagcagc aagactgata atattaggta
     2581 ttggttttca agctgtcaca agagcaggca cctcattttt attgttgaaa gtagcaagat
     2641 atgaattaca agaagttatg agatggctca gtggctcttt atcttttaca aagttagatg
     2701 acatacctct tgttctaata gtaagtatta ttgctactat attagtttta ttttttaata
     2761 aaagactaga aattattgaa cttggtgaag aaatagcaat cggacttgga gcaaatcccg
     2821 agctttcaag gcttgtttta attttttgcg ctgtatcttt aactgctttt tctacttcaa
     2881 ttacaggacc aatagcttgt atatcttttt tagctggtcc catagcctta aatattggca
     2941 agaaaagaag cccaatatta gctggattgg ttggaatttt actagttttg ttatcagaca
     3001 tattctctca aaatatttta ccagctagat atccagtagg tgttgtaact ggcttgttag
     3061 gttcaccata cttaatatac ttactaataa aaatgaacag gaggaatata taatgaaagg
     3121 tctgtggtca aataatctta cctgcggtta tgatgaaaaa ataatcttgg aaaatataaa
     3181 tataaaaata cctgaagaaa aaatatcagt tattattggg tcaaatggtt gtgggaaatc
     3241 aacactcatt aaaaccttgt ctcgacttat aaagccatta gagggagaag tattgctcga
     3301 taataaatca attaattctt ataaagaaaa agatttagca aaacacatag ctatattacc
     3361 tcaatctcca ataatccctg aatcaataac agtagctgat cttgtaagcc gtggtcgttt
     3421 cccctacaga aagcctttta agagtcttgg aaaagatgac cttgaaataa taaacagatc
     3481 aatggttaag gccaatgttg aagatctagc aaataaccta gttgaagaac tttctggggg
     3541 tcaaaggcaa agagtatgga tagctctagc cctagcccaa gatacaagta tcctactttt
     3601 agatgagcca actacttact tggatatctc atatcaaata gaactattag acctcttgac
     3661 tgatctaaac caaaaatata agacaaccat ttgcatgatt ttgcacgata taaatctaac
     3721 agcaagatac gctgattacc tatttgcaat taaagaaggt aaacttgttg cagagggaaa
     3781 gcctgaagat atactaaatg ataaactagt taaagatatc tttaatcttg aagcaaaaat
     3841 tatacgtgac cctatttcca attcgcctct aatgattcct attggcaagc accatgttag
     3901 ctcttaataa ttgaatatcg gaattcattt aaaagtcgca aattttgaac tgaccctcaa
     3961 aagttaggcc aaaaaactaa ctaaaggagg tcagtttttt aatggcaaat acagcacaga
     4021 atttaagata aaattagtaa aagaatatca tgaatgaaaa ataggatata gagaataaca
     4081 gcaatattaa aaagatcagg actgataata aacaaaaaga aagtacaacg actagttcaa
     4141 aagctaaaac ttcaagtaaa aagttattca agaaaatcta gaaaatactc atcctacaaa
     4201 ggacaggtag gaaaaatatc ggacaacaaa ataaaaagaa atatttatta ccgaaaaaaa
     4261 ggggaaatcg agtcaagtac caacaggctc atctattcca aaaagatatt tactcgatgg
     4321 aaaaactcct agaattagtg ctacaaatat tgacaatggt atcttaggtt actacgaaga
     4381 tatagatgat aaaaattata gagtttttga aaattttata tctgtttcat t
//
LOCUS       DBEJAU010000084         4378 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC323 isolate 683620
            SAMN38261939-rid24807223.denovo.084, whole genome shotgun sequence.
ACCESSION   DBEJAU010000084 DBEJAU010000000
VERSION     DBEJAU010000084.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261939
            Sequence Read Archive: SRR26833919
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 4378)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4378)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576303.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576303.1
            Genome Coverage       :: 154x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/19/2025 01:05:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,121
            CDSs (total)                      :: 2,078
            Genes (coding)                    :: 1,943
            CDSs (with protein)               :: 1,943
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 36
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 72 of 135
            Pseudo Genes (incomplete)         :: 63 of 135
            Pseudo Genes (internal stop)      :: 51 of 135
            Pseudo Genes (multiple problems)  :: 46 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4378
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261939-rid24807223.denovo.084"
                     /strain="GPSC323"
                     /isolate="683620"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            287..1832
                     /locus_tag="ACL29Z_002002"
     rRNA            287..1832
                     /locus_tag="ACL29Z_002002"
                     /product="16S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00177"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00177"
     gene            1884..1956
                     /locus_tag="ACL29Z_002003"
     tRNA            1884..1956
                     /locus_tag="ACL29Z_002003"
                     /product="tRNA-Ala"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1917..1919,aa:Ala,seq:tgc)
     gene            2081..>4378
                     /locus_tag="ACL29Z_002004"
     rRNA            2081..>4378
                     /locus_tag="ACL29Z_002004"
                     /product="23S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF02541"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF02541"
BASE COUNT         1251 a          883 c         1280 g          964 t
ORIGIN      
        1 gcggtaacac gggttcgaat cccgtacgga ctatggtatg ttgtggcagg aacacttgat
       61 gaaaaaaagt ttaaaaaaac ttaaaaatct tcaaaaaagt gttgacaagc gaaagcagtt
      121 gtgatatact aatatagttg tcgcttgaga gaagcaagtg acaaagacct ttgaaaactg
      181 aacaagacga accaatgtgc agggcgctac aacgtaagtt gtagtactga acaatgaaaa
      241 aaacaataaa tctgtcagtg acagaaatga gtaagaactc aaacttttta atgagagttt
      301 gatcctggct caggacgaac gctggcggcg tgcctaatac atgcaagtag aacgctgaag
      361 gaggagcttg cttctctgga tgagttgcga acgggtgagt aacgcgtagg taacctgcct
      421 ggtagcgggg gataactatt ggaaacgata gctaataccg cataagagta gatgttgcat
      481 gacatttgct taaaaggtgc acttgcatca ctaccagatg gacctgcgtt gtattagcta
      541 gttggtgggg taacggctca ccaaggcgac gatacatagc cgacctgaga gggtgatcgg
      601 ccacactggg actgagacac ggcccagact cctacgggag gcagcagtag ggaatcttcg
      661 gcaatggacg gaagtctgac cgagcaacgc cgcgtgagtg aagaaggttt tcggatcgta
      721 aagctctgtt gtaagagaag aacgagtgtg agagtggaaa gttcacactg tgacggtatc
      781 ttaccagaaa gggacggcta actacgtgcc agcagccgcg gtaatacgta ggtcccgagc
      841 gttgtccgga tttattgggc gtaaagcgag cgcaggcggt tagataagtc tgaagttaaa
      901 ggctgtggct taaccatagt aggctttgga aactgtttaa cttgagtgca agaggggaga
      961 gtggaattcc atgtgtagcg gtgaaatgcg tagatatatg gaggaacacc ggtggcgaaa
     1021 gcggctctct ggcttgtaac tgacgctgag gctcgaaagc gtggggagca aacaggatta
     1081 gataccctgg tagtccacgc tgtaaacgat gagtgctagg tgttagaccc tttccggggt
     1141 ttagtgccgt agctaacgca ttaagcactc cgcctgggga gtacgaccgc aaggttgaaa
     1201 ctcaaaggaa ttgacggggg cccgcacaag cggtggagca tgtggtttaa ttcgaagcaa
     1261 cgcgaagaac cttaccaggt cttgacatcc ctctgaccgc tctagagata gagttttcct
     1321 tcgggacaga ggtgacaggt ggtgcatggt tgtcgtcagc tcgtgtcgtg agatgttggg
     1381 ttaagtcccg caacgagcgc aacccctatt gttagttgcc atcatttagt tgggcactct
     1441 agcgagactg ccggtaataa accggaggaa ggtggggatg acgtcaaatc atcatgcccc
     1501 ttatgacctg ggctacacac gtgctacaat ggctggtaca acgagtcgca agccggtgac
     1561 ggcaagctaa tctcttaaag ccagtctcag ttcggattgt aggctgcaac tcgcctacat
     1621 gaagtcggaa tcgctagtaa tcgcggatca gcacgccgcg gtgaatacgt tcccgggcct
     1681 tgtacacacc gcccgtcaca ccacgagagt ttgtaacacc cgaagtcggt gaggtaaccg
     1741 taaggagcca gccgcctaag gtgggataga tgattggggt gaagtcgtaa caaggtagcc
     1801 gtatcggaag gtgcggctgg atcacctcct ttctaaggat aaggaactgc gcattggtct
     1861 tgtttagtct tgagaggtct tgtggggcct tagctcagct gggagagcgc ctgctttgca
     1921 cgcaggaggt cagcggttcg atcccgctag gctccattgg tgagagatca ccaagtaatg
     1981 cacattgaaa attgaatatc tatatcaaat agtaacaaga aaataaaccg aaaacgctgt
     2041 agtattaata agagtttatg actgaaaggt cagaaaataa ggttaagtta ataagggcgc
     2101 acggtggatg ccttggcact aggagccgac gaaggacgtg acaaacgacg atatgccttg
     2161 ggtagctgta agtaagcgat gatccaggga tttccgaatg ggggaaccca acaggtagta
     2221 cctgttaccc acatctgtta aggatgtgag gaggaagacg cagtgaactg aaacatctaa
     2281 gtagctgcag gaagagaaag caaaagcgat tgccttagta gcggcgagcg aaacggcaga
     2341 agggcaaacc gaagagttta ctcttcgggg ttgtaggact gcaatgtgga ctcaaagatt
     2401 atagaagaat gatttgggaa gatcagccaa agagagtaat agcctcgtat ttaaaatagt
     2461 ctttgtacct agcagtatcc tgagtacggc gggacacgtg aaatcccgtc ggaatctggg
     2521 aggaccatct cccaacccta aatactccct agtgaccgat agtgaaccag taccgtgagg
     2581 gaaaggtgaa aagcaccccg ggaggggagt gaaatagaac ctgaaaccgt gtgcctacaa
     2641 caagttcgag cccgttaatg ggtgagagcg tgccttttgt agaatgaacc ggcgagttac
     2701 gttatgatgc gaggttaagt tgaagagacg gagccgtagg gaaaccgagt ctgaataggg
     2761 cgccttagta tcatgacgta gacccgaaac catgtgacct acccatgagc aggttgaagg
     2821 tgcggtaaga cgcactggag gaccgaacca gggcacgttg aaaagtgctt ggatgacttg
     2881 tgggtagcgg agaaattcca aacgaacttg gagatagctg gttctctccg aaatagcttt
     2941 agggctagcg tcgacattag agattcttgg aggtagagca ctgtttgggt gaggggtcca
     3001 tcccggatta ccaatctcag ataaactccg aatgccaatg aattatggtc ggcagtcaga
     3061 ctgcgagtgc taagatccgt agtcgaaagg gaaacagccc agaccaccag ctaaggtccc
     3121 aaaataattg ttaagtggaa aaggatgtgg ggttgcacag acaactagga tgttagctta
     3181 gaagcagcta ttcattcaaa gagtgcgtaa tagctcacta gtcgagtgac cctgcgccga
     3241 aaatgtaccg gggctaaaac aatttaccga agctgtggat acctttatag gtatggtagg
     3301 agagcgttct atgtgtgatg aaggtatacc gtgaggagtg ctggaacgca tagaagtgag
     3361 aatgccggta tgagtagcga aagacaggtg agaatcctgt ccaccgtaag actaaggttt
     3421 ccaggggaag gctcgtccgc cctgggttag tcgggaccta aggagagacc gaaaggtgta
     3481 tccgatggac aacaggttga tattcctgta ctagagtatg tagtgatgga gggacgcagt
     3541 aggctaacta aagcagacga ttggaagagt ctgtctaagc agtgaggtgt gaattgagtc
     3601 aaatgcttaa ttctataaca ttgagctgtg atggggagcg aagtttagta gcgaagttag
     3661 tgacgtcaca ctgccaagaa aagcttctag cgtttaaaca tactctaccc gtaccgcaaa
     3721 ccgacacagg tagtcgaggc gagtagcctc aggtgagcga gagaactctc gttaaggaac
     3781 tcggcaaaat gaccccgtaa cttcgggaga aggggtgctg actttaagtc agccgcagtg
     3841 aataggccca agcaactgtt tatcaaaaac acagctctct gctaaatcgt aagatgatgt
     3901 atagggggtg acgcctgccc ggtgctggaa ggttaagagg agtgcttagc gtaagcgaag
     3961 gtatgaattg aagccccagt aaacggcggc cgtaactata acggtcctaa ggtagcgaaa
     4021 ttccttgtcg ggtaagttcc gacccgcacg aaaggcgtaa tgatttgggc actgtctcaa
     4081 cgagagactc ggtgaaattt tagtacctgt gaagatgcag gttacccgcg acaggacgga
     4141 aagaccccat ggagctttac tgcagtttga tattgagtgt ctgtaccaca tgtacaggat
     4201 aggtaggagt ctaagagatc gggacgccag tttcgaagga gacgctgttg ggatactacc
     4261 cttgtgttat ggccactcta acccagatag gtgatcccta tcggagacag tgtctgacgg
     4321 gcagtttgac tggggcggtc gcctcctaaa aggtaacgga ggcgcccaaa ggttccct
//
LOCUS       DBEJAU010000085         4373 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC323 isolate 683620
            SAMN38261939-rid24807223.denovo.085, whole genome shotgun sequence.
ACCESSION   DBEJAU010000085 DBEJAU010000000
VERSION     DBEJAU010000085.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261939
            Sequence Read Archive: SRR26833919
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 4373)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4373)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576303.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576303.1
            Genome Coverage       :: 154x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/19/2025 01:05:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,121
            CDSs (total)                      :: 2,078
            Genes (coding)                    :: 1,943
            CDSs (with protein)               :: 1,943
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 36
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 72 of 135
            Pseudo Genes (incomplete)         :: 63 of 135
            Pseudo Genes (internal stop)      :: 51 of 135
            Pseudo Genes (multiple problems)  :: 46 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4373
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261939-rid24807223.denovo.085"
                     /strain="GPSC323"
                     /isolate="683620"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            121..1455
                     /gene="pepC"
                     /locus_tag="ACL29Z_002005"
     CDS             121..1455
                     /gene="pepC"
                     /locus_tag="ACL29Z_002005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000991632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase C"
                     /protein_id="HGR0070250.1"
                     /translation="MNAIQESFTDKLFANYEANVKYQAIENAASHNGIFAALECRQSH
                     VDNTPVFSLDLTKDKVTNQKASGRCWMFAALNTFRHKLISQYKLENFELSQAHTFFWD
                     KYEKSNWFLEQVIATSDQELTSRKVSFLLQTPQQDGGQWDMVVSLFEKYGVVPKSVYP
                     ESVSSSSSRELNAILNKLLRQDAQILRDLLVSGADQATVQAKKEDLLQEIFNFLAMSL
                     GLPPRKFDFAYRDKDNNYKSEKGITPQEFYKKYVNLPLEDYVSVINAPTADKPYGKSY
                     TVEMLGNVVGSRAVRYINVPMERLKELAIAQMQAGETVWFGSDVGQLSNRKAGILATD
                     VYDFESSMDIKLTQDKAGRLDYSESLMTHAMVLTGVDLDENGKSTKWKVENSWGDKVG
                     TDGYFVASDAWMDEYTYQIVVRKELLTAEEQAAYGAEPIVLAPWDPMGALAE"
     gene            complement(1511..2422)
                     /locus_tag="ACL29Z_002006"
     CDS             complement(1511..2422)
                     /locus_tag="ACL29Z_002006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000136863.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HGR0070251.1"
                     /translation="MTEKLQLTKSDRKKVWWRSTFLQGSWNFERMQNLGWAYTLIPAI
                     KKLYTKKEDQIAALERHLEFFNTHPYVAAPVMGVTLALEEERANGVEIDDAAIQGVKI
                     GMMGPLAGIGDPVFWFTVRPILGSLGASLALTGNILGPLLFFVAWNLIRMSFLWYVQE
                     IGYKAGSEITKDMSGGILQDITKGASILGMFILAVLVQRWVNIKFAFDVSKVQLDEKA
                     YIHWDKLPEGSKGIQEAFAQVGQGLSQTPEKVTTFQQNLDMLIPGLSGLLLTLLCMYL
                     LKKKVSPITIILALFAVGIVAHVLHIM"
     gene            complement(2446..3249)
                     /locus_tag="ACL29Z_002007"
     CDS             complement(2446..3249)
                     /locus_tag="ACL29Z_002007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000022712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0034219 - carbohydrate transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter subunit
                     IIC"
                     /protein_id="HGR0070252.1"
                     /translation="MSIISMVLVVVVAFFAGLEGILDQFQFHQPLVACTLIGLVTGHL
                     EAGIILGGSLQMIALGWSNIGAAIAPDAALASVAAAIIMVLGGDFTKTGIGVAQAVAI
                     PLAVAGLFLTMIVRTISVGLVHTADAAAKKGDFGAVERAHFIALLFQGLRIALPAALL
                     LMVPTETVQSILSAMPDWLKDGMAIGGGMVVAVGYAMVINMMATREVWPFFALGFVLA
                     AVSDITLIGFGAIGVAIALIYLHLSKTGGNGGGGAATSNDPIGDILEDY"
     gene            complement(3277..4266)
                     /locus_tag="ACL29Z_002008"
     CDS             complement(3277..4266)
                     /locus_tag="ACL29Z_002008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000021981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HGR0070253.1"
                     /translation="MSIGIIIASHGEFAAGIHQSGSMIFGEQEKVQVVTFMPNEGPDD
                     LYAKFNNAVAAFDAEDEVLVLADLWSGSPFNQASRVMGENPERKFAIITGLNLPMLIQ
                     AYTERLMDAAAGVEKVAANIIKEAKDGIKALPEELNPVEEVASAAAAPVAQTAIPEGT
                     VIGDGKLKINLARLDTRLLHGQVATAWTPDSKANRIIVASDNVAKDDLRKELIKQAAP
                     GNVKANVVPIQKLIEISKDPRFGETHALILFETPQDALRAIEGGVPIKTLNVGSMAHS
                     TGKTLVNTVLSMDKEDVATFEKMRDLGVEFDVRKVPNDSKKDLFDLINKANVK"
BASE COUNT         1325 a          921 c          934 g         1193 t
ORIGIN      
        1 agattttcga agagtataaa ttcgaaaaag gtgagggaca atgtcctcgc cttttatgtt
       61 ttttagttgc ttcctttgtg aaaagagtta taatagactg tagaataaaa ggaggaatct
      121 atgaacgcga ttcaagaatc atttactgat aaactatttg ccaactatga agcaaatgta
      181 aaataccaag cgattgaaaa tgctgccagc cacaacggaa tttttgcagc tctggaatgt
      241 cgccaaagcc atgtagacaa cacacctgtt ttctcattgg atttaaccaa ggacaaggtc
      301 actaaccaga aagcgtctgg tcgttgctgg atgtttgcgg ctctcaacac cttccgccac
      361 aaactcatct cgcaatacaa attggagaac tttgagttgt cacaagccca cactttcttc
      421 tgggataagt atgagaaatc aaactggttc ttggagcaag tcattgcgac ttcagaccaa
      481 gaattgacta gccgcaaggt tagcttctta ctccaaacac ctcaacaaga tggcggtcaa
      541 tgggatatgg tcgtttccct ctttgaaaaa tacggtgtcg tgcctaagtc agtttatcct
      601 gagtctgttt catctagcag cagtcgtgag ctaaatgcga tccttaataa attgcttcgt
      661 caagatgctc aaatcttgcg tgatttgctt gtttctggtg cagatcaagc gactgttcaa
      721 gctaagaaag aagacctctt gcaagaaatc tttaactttc ttgctatgtc attaggactt
      781 ccaccacgca agtttgactt tgcttatcgc gataaagata acaactataa aagtgaaaaa
      841 ggaatcacac cacaagagtt ttacaagaaa tatgtcaatc ttcctttaga agactacgtt
      901 tctgttatca atgctccaac tgctgataaa ccttacggaa aatcttacac agttgagatg
      961 ttggggaatg tggttggtag ccgtgcagtt cgctacatca acgttccaat ggagcgcttg
     1021 aaagaattgg cgattgccca aatgcaagca ggtgagactg tttggtttgg ttctgatgtc
     1081 ggccagctca gcaaccgtaa ggctggcatc cttgcgacag atgtttatga ctttgaatca
     1141 agcatggaca ttaaacttac tcaagacaag gctggacgtt tggactatag cgaaagcttg
     1201 atgacccacg ccatggtctt gacaggtgtt gacttggacg aaaatggtaa atcaaccaag
     1261 tggaaggttg aaaactcatg gggagacaag gtcggtacag atggttactt tgttgcctca
     1321 gacgcttgga tggacgaata cacataccaa atcgttgttc gtaaggaatt gctgacagca
     1381 gaagaacaag ctgcctatgg agcagaacca atcgtacttg caccatggga tccaatggga
     1441 gccttggctg aataaaagca tagaaaaaag gaatcagatt ttagaacctg gttccttttt
     1501 agttgcttga ttacatgatg tgaagaacat gtgccacaat acccactgcg aagagggcaa
     1561 ggataatagt gattggagat acttttttct taagtaagta catgcaaagt aaagtaagga
     1621 gtagtcctga taatccagga atcaacatat ccaagttttg ttggaaagta gtaacttttt
     1681 caggagtttg agacaatcct tgtcctactt gtgcgaatgc ttcttggata cctttagacc
     1741 cttctggcaa tttatcccaa tggatataag ccttttcatc tagttgaact ttagaaacat
     1801 cgaaagcaaa tttaatattt acccagcgtt gaacaaggac agcaagaatg aacatcccaa
     1861 ggatagaagc tcctttagtg atatcttgaa ggataccacc agacatatct ttagtgattt
     1921 ctgatccagc cttgtatcca atctcttgaa cataccacaa gaatgacata cgaatcaagt
     1981 tccatgcaac aaagaagagg agtggcccca agatattgcc agtaagggca agtgaagcac
     2041 cgagagatcc aaggattggg cgtactgtaa accagaatac tgggtcaccg ataccagcaa
     2101 gaggtcccat cataccgatt ttaacccctt ggatagcagc gtcatcgatt tccacaccgt
     2161 tagcacgttc ttcttcaagc gcaagagtaa cccccatgac tggagcagct acgtatggat
     2221 gagtgttgaa gaactcaagg tgacgctcaa gagcagcgat ttgatcttct tttttagtat
     2281 agagtttttt gatagctgga atgagtgtat aagcccagcc caagttttgc atccgttcaa
     2341 agttccaaga cccttgtaag aaggttgaac gccaccaaac ttttttacga tctgatttag
     2401 ttaattgaag tttttcagtc atgatgtttt cagtcctttc ttatcttagt agtcttctag
     2461 gatatcgccg attgggtcgt tagaagttgc ggctcctccg ccaccatttc caccagtttt
     2521 agaaaggtga aggtagataa gagcgatagc aacaccgata gcaccgaatc cgattagagt
     2581 aatatctgac acagcagcga gaacgaaacc aagagcgaag aatggccata cttcacgagt
     2641 tgccatcatg ttgataacca tggcgtaacc aacggcaacg accataccac caccgatagc
     2701 cataccatct ttgagccagt ctggcatggc actaaggata ctttgtacag tttcagttgg
     2761 taccataagg agaagagctg caggaagcgc gatacgaagt ccttggaaaa gtagcgcaat
     2821 gaaatgagca cgctccacag cgccgaagtc acctttttta gcggcagcat cagcagtgtg
     2881 aaccaatcca actgaaattg tacgaacaat catagttaag aatagaccag ctacggcaag
     2941 agggatagca accgcttggg caacaccgat accagtcttg gtaaagtcac caccaagaac
     3001 catgataatg gcagcagcga cagaagcaag tgcagcatca ggagcgatag cagcaccgat
     3061 atttgaccaa ccaagggcaa tcatttgaag cgatccaccg aggataatcc ctgcttccaa
     3121 gtgacctgtt acaagcccaa taagggtaca ggctacaagt ggttggtgaa attggaactg
     3181 gtcgaggatg ccttcaagac ctgcaaagaa ggctacaacg actactaaaa ccatagaaat
     3241 aatagacatg tttaaaatcc tttcataaat aatggcttat ttgacattgg ctttgttaat
     3301 caagtcaaac aaatcttttt tagaatcatt tggtacttta cggacatcaa attcaacacc
     3361 caagtcacgc attttttcaa atgtagcaac atcttctttg tccatagaca aaacggtatt
     3421 gaccaatgtt ttacctgttg agtgagccat agaaccaacg ttaagagtct tgattggcac
     3481 gccgccttcg atggcacgaa gggcatcttg aggtgtttca aacaagataa gggcatgtgt
     3541 ttctccaaaa cgtgggtctt ttgaaatctc aatcagtttt tgaattggaa ccacgttagc
     3601 cttgacatta cctggagctg cttgtttaat caattcttta cgaaggtcgt ctttagccac
     3661 gttatctgaa gcaacgatga tacgatttgc ttttgaatct ggagtccaag cagttgcaac
     3721 ctgaccgtga agtagacgtg tgtcaagacg ggcaagattg attttcaatt taccgtctcc
     3781 gataacagtt ccttctggga tagcagtttg ggcaactgga gcagctgcag cgcttgcaac
     3841 ttcttcaact ggatttagct cttctggaag agctttgatg ccatctttgg cttctttaat
     3901 gatattagca gcgacttttt ctacacctgc agcagcgtcc atgaggcgct ctgtgtaggc
     3961 ttgaatcaac atcggtaagt taagtcctgt gatgatggca aacttacgct caggattttc
     4021 tcccatcacg cgactagctt ggttaaatgg agaaccactc caaaggtcag ccaaaactag
     4081 aacctcatct tctgcgtcaa atgcagcaac agcgttatta aacttagcgt atagatcatc
     4141 aggaccttca tttggcataa aggtcacaac ttgaaccttt tcttgttcac caaagatcat
     4201 agatcctgac tgatgaatac ccgcagcaaa ttcgccgtgg ctcgcaataa tgattccgat
     4261 actcattatt gtcattcctc cttttttgtt ttagttttca tttaagaaaa ctttaagact
     4321 gtttaagtat aaaccgtttt cataaaaaaa gcaactattt atcataaaaa att
//
LOCUS       DBEJAU010000086         4178 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC323 isolate 683620
            SAMN38261939-rid24807223.denovo.086, whole genome shotgun sequence.
ACCESSION   DBEJAU010000086 DBEJAU010000000
VERSION     DBEJAU010000086.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261939
            Sequence Read Archive: SRR26833919
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 4178)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4178)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576303.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576303.1
            Genome Coverage       :: 154x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/19/2025 01:05:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,121
            CDSs (total)                      :: 2,078
            Genes (coding)                    :: 1,943
            CDSs (with protein)               :: 1,943
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 36
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 72 of 135
            Pseudo Genes (incomplete)         :: 63 of 135
            Pseudo Genes (internal stop)      :: 51 of 135
            Pseudo Genes (multiple problems)  :: 46 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4178
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261939-rid24807223.denovo.086"
                     /strain="GPSC323"
                     /isolate="683620"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            complement(369..614)
                     /locus_tag="ACL29Z_002009"
     CDS             complement(369..614)
                     /locus_tag="ACL29Z_002009"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001816931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016747 - acyltransferase activity,
                     transferring groups other than amino-acyl groups [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HGR0070254.1"
                     /translation="MSRRKKAYQGRKIGSQLLATLESEARKKVGYLQVKTVAEGSNKD
                     YDRTNDFYRGLGFKKLEIFFQLWNPQNPCQILIKKLE"
     gene            complement(551..769)
                     /locus_tag="ACL29Z_002010"
     CDS             complement(551..769)
                     /locus_tag="ACL29Z_002010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001814192.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family acetyltransferase"
                     /protein_id="HGR0070255.1"
                     /translation="MKDLPEWFGIPESTQAYIEGTTTLQVWTAYQESDLTGFVRLSYS
                     SEDCAEIDCLGVKKLIKVEKLGANCLLL"
     gene            complement(867..1652)
                     /locus_tag="ACL29Z_002011"
     CDS             complement(867..1652)
                     /locus_tag="ACL29Z_002011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003010202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HGR0070256.1"
                     /translation="MKKYQRMHLIFIRQYIKQIMEYKVDFVVGVLGVFLAQGLNLLFL
                     NVIFQHIPFLEGWTFQEIAFIYGFSLIPKGMDHLFFDNLWALGQRLVRKGEFDKYLTR
                     PINPLFHILVETFQIDALGELLVGGILLGTTVTSIVWTLPKFLLFLVCIPFATLIYTS
                     LKIATASIAFWTKQSGAMIYIFYMFNDFAKYPISIYNSLLRWLISFIVPFAFTAYYPA
                     SYFLQEKDVFFNVGGLMLISLVFFVISLKLWDKGLDSYESAGS"
     gene            complement(1654..2472)
                     /locus_tag="ACL29Z_002012"
     CDS             complement(1654..2472)
                     /locus_tag="ACL29Z_002012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000240175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HGR0070257.1"
                     /translation="MIKLWRRYKPFINAGVQELITYRVNFILYRIGDVMGAFVAFYLW
                     KAVFDSSQESLIQGFSMADITLYIIMSFVTNLLTRSDSSFMIGEEVKDGSIIMRLLRP
                     VHFAASYLFTELGSKWLIFISVGLPFLSVIVLMKIISGQGIVEVLGLTVIYLFSLTLA
                     YLINFFFNICFGFSAFVFKNLWGSNLLKTSIVAFMSGSLIPLAFFPKVVSDILSFLPF
                     SSLIYTPVMIIVGKYDASQILQALLLQFFWLLVMVGLSQLIWKRVQSFITIQGG"
     gene            complement(2474..3466)
                     /locus_tag="ACL29Z_002013"
     CDS             complement(2474..3466)
                     /locus_tag="ACL29Z_002013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018371202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HGR0070258.1"
                     /translation="MAMIEVEHLQKNFVKTVKEPGLKGALRSFIHPEKQTFEAVKDLT
                     FEVPKGQILGFIGANGAGKSTTIKMLTGILKPTSGFCRINGKIPQDNRQDYVKDIGVV
                     FGQRTQLWWDLALQETYTVLKEIYDVPNSLFHKRMDFLNEVLDLKDFIKDPVRTLSLG
                     QRMRADIAASLLHNPKVLFLDEPTIGLDVSVKDNIRRAITQINQEEETTILLTTHDLS
                     DIEQLCDRIFMIDKGQEIFDGTVSQLKETFGKMKTLSFELLPGQSHLVSHYEGLSDMT
                     IDRQGNSLNIEFDSSRYQSADIIKQTLSDFEIRDLKMVDTDIEDIIRRFYRKEL"
     gene            complement(3885..4112)
                     /locus_tag="ACL29Z_002014"
                     /pseudo
     CDS             complement(3885..4112)
                     /locus_tag="ACL29Z_002014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007284765.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
BASE COUNT         1396 a          906 c          714 g         1162 t
ORIGIN      
        1 aaccatacgc acggcaaggc gacgttgacg tggtttgaag agattttcga agagtataag
       61 tccaaaactt tcgttaaccg ggatacatta taagcacatt cataccatca aaaatagtag
      121 caataaactt gaacaactac cagaaacaca aaaacaggca taattgatga aatatcagcg
      181 ctattaaaca atataaataa ccgctaagaa taaggcttaa cggttatctt ctacctatct
      241 attttttcaa ctcctcagtc gtttatctac ctataaccta ggctttacga gtgccttgct
      301 ctaccaactg agctaaatcg gcgattacac ttacagtata gcactctgag aatagatgtc
      361 aagtaatatt attcaagctt tttaatcaaa atctgacaag gattttgcgg attccatagc
      421 tgaaaaaaaa tctctaactt tttaaagcca agacctcgat aaaagtcatt tgttcgatca
      481 taatctttat tagaaccttc tgccactgtt ttgacctgca gataaccaac ttttttacga
      541 gcttcactct ctaaagtagc aagcaattgg ctcccaattt ttctaccttg ataagctttt
      601 ttacgccgag acaatcaatc tctgcacaat cttcactcga ataggataac cttacaaatc
      661 cagtcaaatc actctcctga taggcggtcc aaacttgcag tgtcgtggtt ccttctatat
      721 aggcttgtgt gctttctggg attccaaacc attctggcaa atccttcaaa acctcagcga
      781 caactgcctt ttttgatttt catccttgac ttcttcaatt acaaacatca taagttcctt
      841 tcttgatttt agtcttactt tagcttttac gaacccgcac tttcgtagga atctaagccc
      901 ttatcccaaa gtttaaggga aataacaaag aaaaccagag aaatcaacat caaacctcct
      961 acgttaaaga acacatcctt ttcctgtaag aaatagctag ctggatagta ggctgtaaag
     1021 gcgaaaggca cgataaagct aatcaaccaa cgaagaagag aattgtaaat agaaatcgga
     1081 tacttagcaa agtcattgaa catataaaag atgtaaatca tggcgcctga ctgcttagtc
     1141 caaaaggcga tactggctgt tgcgatttta agagaagtat aaatcaaggt cgcaaaagga
     1201 atacaaacta ggaaaagcag gaattttgga agagtccaaa caatgctggt cactgttgtt
     1261 cccaataaaa taccaccgac taagagttca cccaaggcat caatctgaaa ggtttcaact
     1321 aggatatgaa agagaggatt gatgggacga gtcagatact tgtcaaactc cccttttcgg
     1381 actaggcgtt gccctagtgc ccagagattg tcaaaaaaga gatggtccat tcccttggga
     1441 atcaaggaaa atccataaat gaaagctatc tcttgaaagg tccagccttc taggaatgga
     1501 atatgttgaa agatgacatt gagaaacaag agattcaagc cttgagccag aaagactccc
     1561 aagacaccaa ccacaaaatc caccttatat tccatgattt gtttgatgta ttgtctgata
     1621 aaaatcagat gcattcgttg atattttttc atactaacct ccttgaatgg tgataaagga
     1681 ctggacccgt ttccaaatca actgagacaa tcccaccatc actaagagcc agaagaactg
     1741 caaaaggagt gcctgaagaa tctgactggc atcgtatttt ccaacaatga tcataactgg
     1801 agtataaatc aaggatgaaa aaggcaaaaa ggagagaata tctgaaacaa cctttggaaa
     1861 gaatgccaag ggaatcaaac tccccgacat aaaagccact atggaagtct taagtaggtt
     1921 ggaaccccaa agatttttaa acacaaaggc tgaaaatcca aagcaaatat taaagaaaaa
     1981 gttaatcaga taggcgagcg ttaagctaaa aagataaatg acagttaatc ctagcacctc
     2041 tacaatacct tgacccgata tgattttcat caagacaatg acacttaaaa atggaaggcc
     2101 aacgctgata aaaatcaacc acttggaacc aagctcggtg aaaagatagg aggccgcaaa
     2161 atgcactggt cgcaacaaac gcatgataat ggagccatcc ttgacctcct ccccaatcat
     2221 aaaggacgaa tcggatctag tcagaagatt ggtcacaaaa ctcatgatga tgtagagggt
     2281 gatatccgcc atactgaagc cctgaatcaa agactcttgc gaagaatcaa agacagcctt
     2341 ccagagataa aaggccacaa aagcccccat gacatcgcca atccgataga gaataaagtt
     2401 gactcggtaa gtaatcaact cctgaacccc tgcattgata aagggtttat aacgtctcca
     2461 caatttgatc atcctagagc tcctttcggt agaagcgacg gataatatcc tcaatatccg
     2521 tatccaccat cttcaaatcg cggatttcaa aatcagacag ggtttgcttg ataatgtcag
     2581 ctgactggta gcgagaacta tcaaattcaa tgttgaggct gtttccttgt ctatcaatgg
     2641 tcatatcaga cagaccttca tagtgagaga cgagatgact ttgacctggt agcagttcaa
     2701 aagagagagt cttcatctta ccaaaggtct ccttgagttg gctcaccgtt ccatcaaaaa
     2761 tctcttgccc cttgtcaatc atgaaaatcc gatcacaaag ttgctcaata tcactcaaat
     2821 cgtgagtggt caaaagaatg gtagtttctt cctcttgatt gatctgagta attgcccgac
     2881 gaatattatc cttaaccgaa acgtccaaac caatggtcgg ctcatctaaa aaaagaacct
     2941 tgggattgtg gagcaaggag gccgcaatat ccgcccgcat ccgttgtccc agtgaaagag
     3001 tccgcacggg atccttgata aagtccttca aatccaagac ttcattcaaa aagtccatgc
     3061 gcttatgaaa gagcgagttt ggcacatcat aaatctcttt taagacagtg taggtctctt
     3121 gcagagccaa atcccaccat agctgggtgc gttgtccaaa gactacgcca atatctttga
     3181 cataatcttg ccgattgtcc tggggaatct tgccgttaat ccgacaaaaa ccagatgttg
     3241 gtttcaaaat tcctgtcagc attttaatgg ttgtcgactt cccagcacca tttgccccga
     3301 taaatcctaa aatctgccct tttggaactt caaaggtcaa atccttgacc gcttcaaagg
     3361 tctgcttttc aggatgaata aaggagcgca aagccccctt caagcccggt tccttaacag
     3421 tcttcacaaa atttttctga agatgttcca cttctatcat tgccatatct atctccctat
     3481 cataaggaat agcaacattg tgtttttaac tacaaatatt ctaaatcctt actttctaca
     3541 ccttctacat tttattacta cagaaggctt tataccaacc tattatagtc caataaaaaa
     3601 cagaatgcaa gcgtttgcct atggattgtg aaattaggat ttctctcatg aaataatact
     3661 tttaatcaaa aattctgttt aatagtttaa attaccaatc tactcatctt ctcaccagag
     3721 ggcggtatta actttgatca taaaatcgga tactccctct atccagaaaa tatgctcaga
     3781 atgattgtct ctaaacaata cctgctcttt tacctcattc atgaaaaaga agtccatacc
     3841 ctgagaatta tcaactcacg caccgactac ctaaaccaac tcgatcacct ctttcgtaca
     3901 tgtaggaaac tattttcctc acaaataatc tcattataaa atccaataaa tttttttagc
     3961 tcactttaat attttctttg tatcgtttta tcagctgcaa tctgatctag acttgttacc
     4021 ttggaacgac ttgaaataac ctttgtaaaa taacacttaa ggctttcatc atctcgtata
     4081 aatttttcaa tagtgatata aaaagctttc atattctgtt tgtaatcaga tattaattga
     4141 ttaattttat cattctgatg aagattcgat accataat
//
LOCUS       DBEJAU010000087         3802 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC323 isolate 683620
            SAMN38261939-rid24807223.denovo.087, whole genome shotgun sequence.
ACCESSION   DBEJAU010000087 DBEJAU010000000
VERSION     DBEJAU010000087.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261939
            Sequence Read Archive: SRR26833919
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 3802)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3802)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576303.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576303.1
            Genome Coverage       :: 154x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/19/2025 01:05:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,121
            CDSs (total)                      :: 2,078
            Genes (coding)                    :: 1,943
            CDSs (with protein)               :: 1,943
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 36
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 72 of 135
            Pseudo Genes (incomplete)         :: 63 of 135
            Pseudo Genes (internal stop)      :: 51 of 135
            Pseudo Genes (multiple problems)  :: 46 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3802
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261939-rid24807223.denovo.087"
                     /strain="GPSC323"
                     /isolate="683620"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            <1..418
                     /locus_tag="ACL29Z_002015"
     CDS             <1..418
                     /locus_tag="ACL29Z_002015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000700326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="histidine motif-containing protein"
                     /protein_id="HGR0070259.1"
                     /translation="KNKADQDSKPDEDKGHDEVSEPTHPESDEKENHAGLNPSADNLY
                     KPSTDTEETEEEAEDTTDEAEIPQVEHSVINAKIAEAEALLEKVTDSSIRQNAVETLT
                     GLKSSLLLGTKDNNTISAEVDSLLALLKESQPTPIQ"
     gene            628..3747
                     /gene="phtE"
                     /locus_tag="ACL29Z_002016"
     CDS             628..3747
                     /gene="phtE"
                     /locus_tag="ACL29Z_002016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000672589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal histidine triad protein PhtE"
                     /protein_id="HGR0070260.1"
                     /translation="MKFSKKYIAAGSAVIVSLSLCAYALNQHRSQENKDNNRVSYVDG
                     SQSSQKSENLTPDQVSQKEGIQAEQIVIKITDQGYVTSHGDHYHYYNGKVPYDALFSE
                     ELLMKDPNYQLKDADIVNEVKGGYIIKVDGKYYVYLKDAAHADNVRTKDEINRQKQEH
                     VKDNEKVNSNVAVARSQGRYTTNDGYVFNPADIIEDTGNAYIVPHGGHYHYIPKSDLS
                     ASELAAAKAHLAGKNMQPSQLSYSSTASDNNTQSVAKGSTSKPANKSENLQSLLKELY
                     DSPSAQRYSESDGLVFDPAKIISRTPNGVAIPHGDHYHFIPYSKLSALEEKIARMVPI
                     SGTGSTVSTNAKPNEVVSSLGSLSSNPSSLTTSKELSSASDGYIFNPKDIVEETATAY
                     IVRHGDHFHYIPKSNQIGQPTLPNNSLATPSPSLPINPGTSHEKHEEDGYGFDANRII
                     AEDESGFVMSHGDHNHYFFKKDLTEEQIKAAQKHLEEVKTSHNGLDSLSSHEQDYPSN
                     AKEMKDLDKKIEEKIAGIMKQYGVKRESIVVNKEKNAIIYPHGDHHHADPIDEHKPVG
                     IGHSHSNYELFKPEEGVAKKEGNKVYTGEELTNVVNLLKNSTFNNQNFTLANGQKRVS
                     FSFPPELEKKLGINMLVKLITPDGKVLEKVSGKVFGEGVGNIANFELDQPYLPGQTFK
                     YTIASKDYPEVSYDGTFTVPTSLAYKMASQTIFYPFHAGDTYLRVNPQFAVPKGTDAL
                     VRVFDEFHGNAYLENNYKVGEIKLPIPKLNQGTTRTAGNKIPVTFMANAYLDNQSTYI
                     VEVPILEKENQTDKPSILPQFKRNKAQENSKLDEKVEEPKTSEKVEKEKLSETGNSTS
                     NSTLEEVPTVDPVQEKVAKFAESYGMKLENVLFNMDGTIELYLPSGEVIKKNMADFTG
                     EAPQGNGENKPSENRKVPTGTVENQPTENKPADSLPEAPNEKPVKPENSTDNGMLNPE
                     GNVGSDPMLDPALEEAPAVDPVQEKLEKFTASYGLGLDSVIFNMDGTIELRLPSGEVI
                     KKNLSDLIA"
BASE COUNT         1425 a          625 c          746 g         1006 t
ORIGIN      
        1 taaaaataag gcagaccaag atagtaaacc tgatgaagat aagggacatg atgaagtaag
       61 tgagccaact caccctgaat ctgatgaaaa agagaatcac gctggtttaa atccttcagc
      121 agataatctt tataaaccaa gcactgatac ggaagagaca gaggaagaag ctgaagatac
      181 tacagatgag gctgaaattc ctcaagtaga gcattctgtt attaacgcta agatagcaga
      241 ggcggaggcc ttgctagaaa aagtaacaga ttctagtatt agacaaaatg ctgtggagac
      301 attgactggt ctaaaaagta gtcttcttct cggaacgaaa gataataaca ctatttcagc
      361 agaagtagat agtctcttgg ctttgttaaa agaaagtcaa ccgactccta tacagtagta
      421 aaatgaatgg agcatatttt atggagaagt aacctttcgt gttacttctc ttttttagaa
      481 aaacgtaaca gaaacttgac aaaagtaatt ttaaatagta aactatttac tggttaatta
      541 aatggttaaa taaccggttt agaaaactat ttaataaagt aaaagaagtt gagaaaaaac
      601 ttcatcattt attgaaatga gggatttatg aaattcagta aaaaatatat agcagctgga
      661 tcagctgtta tcgtatcctt gagtctatgt gcctatgcac taaaccagca tcgttcgcag
      721 gaaaataagg acaataatcg tgtctcttat gtagatggca gccagtcaag tcagaaaagt
      781 gaaaacttga caccagacca ggttagccag aaagaaggaa ttcaggccga gcaaattgta
      841 atcaaaatta cagatcaggg ctatgtaacg tcacacggtg accactatca ttactataat
      901 gggaaagttc cttatgatgc cctctttagt gaagaactct tgatgaagga tccaaactat
      961 caacttaaag acgctgatat tgtcaatgaa gtcaagggtg gttatatcat caaggtcgat
     1021 ggaaaatatt atgtctacct gaaagatgca gctcatgctg ataatgttcg aactaaagat
     1081 gaaatcaatc gtcaaaaaca agaacatgtc aaagataatg agaaggttaa ctctaatgtt
     1141 gctgtagcaa ggtctcaggg acgatatacg acaaatgatg gttatgtctt taatccagct
     1201 gatattatcg aagatacggg taatgcttat atcgttcctc atggaggtca ctatcactac
     1261 attcccaaaa gcgatttatc tgctagtgaa ttagcagcag ctaaagcaca tctggctgga
     1321 aaaaatatgc aaccgagtca gttaagctat tcttcaacag ctagtgacaa taacacgcaa
     1381 tctgtagcaa aaggatcaac tagcaagcca gcaaataaat ctgaaaatct ccagagtctt
     1441 ttgaaggaac tctatgattc acctagcgcc caacgttaca gtgaatcaga tggcctggtc
     1501 tttgaccctg ctaagattat cagtcgtaca ccaaatggag ttgcgattcc gcatggcgac
     1561 cattaccact ttattcctta cagcaagctt tctgccttag aagaaaagat tgccagaatg
     1621 gtgcctatca gtggaactgg ttctacagtt tctacaaatg caaaacctaa tgaagtagtg
     1681 tctagtctag gcagtctttc aagcaatcct tcttctttaa cgacaagtaa ggagctctct
     1741 tcagcatctg atggttatat ttttaatcca aaagatatcg ttgaagaaac ggctacagct
     1801 tatattgtaa gacatggtga tcatttccat tacattccaa aatcaaatca aattgggcaa
     1861 ccgactcttc caaacaatag tctagcaaca ccttctccat ctcttccaat caatccagga
     1921 acttcacatg agaaacatga agaagatgga tacggatttg atgctaatcg tattatcgct
     1981 gaagatgaat caggttttgt catgagtcac ggagaccaca atcattattt cttcaagaag
     2041 gacttgacag aagagcaaat taaggctgcg caaaaacatt tagaggaagt taaaactagt
     2101 cataatggat tagattcttt gtcatctcat gaacaggatt atccaagtaa tgccaaagaa
     2161 atgaaagatt tagataaaaa aatcgaagaa aaaattgctg gcattatgaa acaatatggt
     2221 gtcaaacgtg aaagtattgt cgtgaataaa gaaaaaaatg cgattattta tccgcatgga
     2281 gatcaccatc atgcagatcc gattgatgaa cataaaccgg ttggaattgg tcattctcac
     2341 agtaactatg aactgtttaa acccgaagaa ggagttgcta aaaaagaagg gaataaagtt
     2401 tatactggag aagaattaac gaatgttgtt aatttgttaa aaaatagtac gtttaataat
     2461 caaaacttta ctctagccaa tggtcaaaaa cgcgtttctt ttagttttcc gcctgaattg
     2521 gagaaaaaat taggtatcaa tatgctagta aaattaataa caccagatgg aaaagtattg
     2581 gagaaagtat ctggtaaagt atttggagaa ggagtaggga atattgcaaa ctttgaatta
     2641 gatcaacctt atttaccagg acaaacattt aagtatacta tcgcttcaaa agattatcca
     2701 gaagtaagtt atgatggtac atttacagtt ccaacctctt tagcttacaa aatggccagt
     2761 caaacgattt tctatccttt ccatgcaggg gatacttatt taagagtgaa ccctcaattt
     2821 gcagtgccta aaggaactga tgctttagtc agagtgtttg atgaatttca tggaaatgct
     2881 tatttagaaa ataactataa agttggtgaa atcaaattac cgattccgaa attaaaccaa
     2941 ggaacaacca gaacggccgg aaataaaatt cctgtaacct tcatggcaaa tgcttatttg
     3001 gacaatcaat cgacttatat tgtggaagta cctatcttgg aaaaagaaaa tcaaactgat
     3061 aaaccaagta ttctaccaca atttaaaagg aataaagcac aagaaaactc aaaacttgat
     3121 gaaaaggtag aagaaccaaa gactagtgag aaggtagaaa aagaaaaact ttctgaaact
     3181 gggaatagta ctagtaattc aacgttagaa gaagttccta cagtggatcc tgtacaagaa
     3241 aaagtagcaa aatttgctga aagttatggg atgaagctag aaaatgtctt gtttaatatg
     3301 gacggaacaa ttgaattata tttaccatcg ggagaagtca ttaaaaagaa tatggcagat
     3361 tttacaggag aagcacctca aggaaatggt gaaaataaac catctgaaaa tagaaaagta
     3421 cctactggaa cagttgagaa ccaaccaaca gaaaataaac cagcagattc tttaccagag
     3481 gcaccaaacg aaaaacctgt aaaaccagaa aactcaacgg ataatggaat gttgaatcca
     3541 gaagggaatg tggggagtga ccctatgtta gatccagcat tagaggaagc tccagcagta
     3601 gatcctgtac aagaaaaatt agaaaaattt acagctagtt acggattagg cttagatagt
     3661 gttatattca atatggatgg aacgattgaa ttaagattgc caagtggaga agtgataaaa
     3721 aagaatttat ctgatctcat agcgtaagga atagcagtag aaaaagtctg aatcaaaaat
     3781 gaagttctct caaaagttag aa
//
LOCUS       DBEJAU010000088         3791 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC323 isolate 683620
            SAMN38261939-rid24807223.denovo.088, whole genome shotgun sequence.
ACCESSION   DBEJAU010000088 DBEJAU010000000
VERSION     DBEJAU010000088.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261939
            Sequence Read Archive: SRR26833919
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 3791)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3791)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576303.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576303.1
            Genome Coverage       :: 154x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/19/2025 01:05:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,121
            CDSs (total)                      :: 2,078
            Genes (coding)                    :: 1,943
            CDSs (with protein)               :: 1,943
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 36
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 72 of 135
            Pseudo Genes (incomplete)         :: 63 of 135
            Pseudo Genes (internal stop)      :: 51 of 135
            Pseudo Genes (multiple problems)  :: 46 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3791
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261939-rid24807223.denovo.088"
                     /strain="GPSC323"
                     /isolate="683620"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            complement(21..1376)
                     /gene="rlmD"
                     /locus_tag="ACL29Z_002017"
     CDS             complement(21..1376)
                     /gene="rlmD"
                     /locus_tag="ACL29Z_002017"
                     /EC_number="2.1.1.190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008649 - rRNA methyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (uracil(1939)-C(5))-methyltransferase
                     RlmD"
                     /protein_id="HGR0070261.1"
                     /translation="MNLKVKQKIPLKIKRMGINGEGIGFYQKTLVFVPGALKGEDIYC
                     QITSIRRNFVEAKLLKVNKKSKFRIVPSCTIYNECGGCQIMHLHYDKQLEFKTDLLHQ
                     ALKKFAPAGYENYEIRPTIGMQEPKYYRAKLQFQTRKFKNQVKAGLYAQNSHYLVELK
                     DCLVQDKETQVIANRLAELLTYHQIPITDERKVLGVRTIMVRRARKTGQVQIIIVTNR
                     QLNLTQLVKELVKDFPEVVTVAVNTNTAKTSEIYGEKTEIIWGQESIQEGVLNYEFSL
                     SPRAFYQLNPEQTEVLYSEAVKALDVDKEDHLIDAYCGVGTIGFAFAKKVKTLRGMDI
                     IPEAIEDAKRNAKRMGFDNTHYEAGTAEEIIPRWYKEGYRADALIVDPPRTGLDDKLL
                     DTILTYVPEKMVYISCNVSTLARDLVRLVEVYDLHYIQSVDMFPHTARTEAVVKLIKK
                     V"
     gene            1414..2190
                     /gene="recX"
                     /locus_tag="ACL29Z_002018"
     CDS             1414..2190
                     /gene="recX"
                     /locus_tag="ACL29Z_002018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000705102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006282 - regulation of DNA repair
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="recombination regulator RecX"
                     /protein_id="HGR0070262.1"
                     /translation="MKITKLEKKKRLYLMELDNGDKCYITEDTIVRFMLSRDKVISEE
                     ELKEIQDFAQFSYGKNLALYHLSFKARTEKEVREYLKKYDIDKNIVSQVIANLKEDKW
                     INDGQYAYAIINTNQLSGDKGPYVLTQKLAQKGISKSTIEENLKEFDFSEVAQRVANK
                     LLKKYEGKLPSRALQDKIIQNLTNKGFSYSDAKIAFDDLDSQVDQETTQELIFKELDK
                     QYTKYARKYEGYELKQRLSQVLARKGYDFSDIASALREYL"
     gene            2279..2812
                     /locus_tag="ACL29Z_002019"
     CDS             2279..2812
                     /locus_tag="ACL29Z_002019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000775318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF402 domain-containing protein"
                     /protein_id="HGR0070263.1"
                     /translation="MKLPKEGDFITIQSYKHDGSLHRTWRDTMVLKTTENAIIGVNDH
                     TLVTESDGRRWVTREPAIVYFHKKYWFNIIAMIRDNGTSYYCNMASPYYLDEEALKYI
                     DYDLDVKIFTDGEKRLLDVEEYERHKRKMNYSDDLDYILKEHVKILVDWINNGRGPFS
                     EAYVNIWYKRYVELKNR"
     gene            complement(3166..3675)
                     /locus_tag="ACL29Z_002020"
     CDS             complement(3166..3675)
                     /locus_tag="ACL29Z_002020"
                     /inference="COORDINATES: protein motif:HMM:TIGR01716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0070264.1"
                     /translation="MVQGLLNQLDCNHVVSRDDLNLVYDYLFQKERWESYEITLIGNL
                     YHLFEIDYIYMVGKEILERTHYYEKIGKNRNLVVSACLNFWFCCLENSHLIYADYFEM
                     KLQKLLKDDTKVFEKSTFKFVEGYKIYLTESKESGIKQMDNVIKYFEFIESKSIALYF
                     QKRLNELID"
     gene            complement(3684..>3791)
                     /locus_tag="ACL29Z_002021"
     CDS             complement(3684..>3791)
                     /locus_tag="ACL29Z_002021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007284801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XRE family transcriptional regulator"
                     /protein_id="HGR0070265.1"
                     /translation="VNLSPNFYSLNIKGLEVIKNEQQKLFEKSGEKLIK"
BASE COUNT         1247 a          668 c          612 g         1264 t
ORIGIN      
        1 atgttttgtc aacacctttt ttaaactttt tttattaatt ttacaacagc ttcagttcga
       61 gctgtatgtg ggaacatatc gaccgactgg atataatgaa gatcatagac ttctactaag
      121 cgtaccaaat cacgagccaa ggtcgaaaca ttacaagaaa tataaaccat tttttctggt
      181 acataagtaa gaatagtatc taataactta tcatccagac ctgtacgtgg tgggtcaaca
      241 atcaaagcat ctgctcggta gccttccttg taccaacgag gaataatctc ttctgccgtt
      301 ccagcttcat aatgagtatt gtcaaatccc attcttttag catttcgctt ggcatcttca
      361 atagcttctg gaataatatc catacctctg agtgttttta ctttctttgc aaaggcaaat
      421 ccaatcgttc caactccaca ataagcgtca atcaaatggt cttctttatc aacatccagc
      481 gcttttactg cttcgctata gaggacttct gtttgctcag gatttagttg ataaaaagct
      541 ctaggggata gtgaaaattc ataattgagt acaccttctt gaatactctc ttgcccccag
      601 ataatctctg tcttttcacc atatatctca ctggttttag ctgtatttgt attaacagct
      661 actgtcacaa cttctgggaa atctttaacc aactctttta ccaattgagt taaattaagc
      721 tggcggtttg taacaataat aatctgaacc tgtccggtct ttctcgcgcg tcggaccata
      781 atagtacgga cacctagaac ttttctctca tccgtgattg gaatctggtg ataagtaagt
      841 aattctgcta agcgattagc aatcacttgg gtttccttat cttgtaccag gcagtctttc
      901 aactctacta aatagtgaga gttttgtgca tataagcccg ccttgacctg atttttaaat
      961 tttcgagtct gaaattgtaa cttagctctg taatattttg gttcctgcat tccaatagtt
     1021 ggacgaattt cataattttc atatcctgca ggagcaaatt ttttcagcgc ttgatgaagt
     1081 aagtccgtct tgaactccag ctgcttatca taatgcaggt gcatgatttg gcagcctccg
     1141 cattcattat aaatagtaca agatggcaca attcgaaatt tagacttctt gttgaccttc
     1201 agtaattttg cttcaacaaa gttgcgtcta atagaagtaa tctgacaata gatatcttcg
     1261 cctttgagag ctcctggtac aaagactaat gttttttggt aaaagccgat tccctcaccg
     1321 ttaattccca tgcgcttgat ttttaatggt attttttgtt tcactttcag attcataccc
     1381 ctatcttatc acattttgag ttataataga gctatgaaaa tcacaaaact tgaaaagaaa
     1441 aaaagactct atctgatgga gcttgataat ggcgacaaat gctatatcac cgaagataca
     1501 attgttcgtt ttatgttatc gagagataag gtgataagcg aagaggaatt gaaagagatt
     1561 caagactttg ctcaattttc ttatggtaag aatctggccc tctaccactt atcctttaaa
     1621 gcacgcactg aaaaagaagt cagagaatat ctgaaaaaat acgatattga taaaaacatt
     1681 gtttctcaag ttattgctaa tcttaaagaa gataagtgga ttaatgatgg tcagtacgct
     1741 tatgctatca tcaataccaa tcaactttca ggagacaagg gtccttatgt gctgactcaa
     1801 aaactagctc aaaaagggat ttcaaaatct actatagaag agaacttgaa agaatttgat
     1861 ttttctgaag ttgctcaacg tgtagctaat aaactattga aaaaatatga gggaaaactt
     1921 ccatctcgtg ccctgcaaga taagattatc cagaacttga ctaacaaggg cttctcttat
     1981 tctgatgcta aaattgcctt tgacgactta gatagccaag ttgaccaaga aacgactcaa
     2041 gaactcatct tcaaggaact tgataagcaa tatactaagt atgctcgaaa gtatgaagga
     2101 tacgaactga agcagcgttt aagtcaagtt ttagcacgaa agggctacga tttttcggat
     2161 atagcaagcg ctcttagaga atatctttaa tatttccaag tgaaattcac agattttagg
     2221 taattttatg gtacaatagt aaatgataaa cttataaatt gtagaaagtt ggttagttat
     2281 gaagcttcca aaagaaggcg actttattac aattcaaagt tataagcatg atgggagtct
     2341 tcaccgaact tggcgggaca ccatggtact aaaaacaaca gaaaacgcca ttattggtgt
     2401 taacgatcat acacttgtta ccgaaagtga tggtcgtcgt tgggtcactc gagaaccggc
     2461 tattgtttac tttcacaaga aatattggtt taatatcatt gccatgattc gtgataatgg
     2521 aacttcttac tattgcaata tggctagccc ctactatctg gatgaagaag cactgaagta
     2581 tattgattac gatttggatg ttaaaatttt tacagatggt gaaaaacgtc tcttggacgt
     2641 tgaagagtac gagcgtcaca aacgcaaaat gaattattct gatgacttgg actatatttt
     2701 aaaagaacat gtcaaaattc ttgttgattg gattaacaat ggacgtggtc ctttctcaga
     2761 agcctatgta aacatttggt acaagcgcta tgtagaacta aagaatcggt aaagttgtca
     2821 aaggtcagga acaaaatcct gacctttttt tggtagtata aaataaattg tgtaaacaca
     2881 aaaaggaata aatccattat agcagagtta caacacatta ctagaaagag atttatgcag
     2941 aattcgtaaa atatataaaa caaatagata tactgttatt ttttaatgtc tttattcctt
     3001 gtaagtttac aacaaactta tatcgtttaa tacaaaaaat acgaaaatga ttagtataaa
     3061 aaatacaggt caacttcgta tcaaaaacat tttttgtatt tccacatagc atcaatcatt
     3121 tagtacaata ttttaaaaac aatatctcaa cagagaaaat gctatttaat ctatcagctc
     3181 atttaatcgt ttttgaaaat ataaagcaat acttttagat tcaataaact caaaatattt
     3241 tatgacattg tccatttgtt taattccaga ttctttagat tctgtcaggt atattttata
     3301 tccttctaca aatttgaatg tagatttttc aaaaactttt gtgtcatctt ttaataattt
     3361 ttgtaatttc atttcaaagt agtctgcata tattagatgt gaattttcaa ggcaacagaa
     3421 ccaaaaattt aaacaagctg acacaactaa atttctattc ttgccgattt tttcgtaata
     3481 atgtgtacgc tctagtattt cttttccgac catgtaaata taatctattt caaaaagatg
     3541 atataaatta ccaatcagcg ttatctcata ggactcccat cgttccttct ggaataaata
     3601 gtcatatact aaatttagat catctctact aactacatga ttacaatcta gctgatttaa
     3661 taatccctga accataattg tatttatttt atgagttttt ccccactctt ctcaaaaagt
     3721 ttttgttgct cattttttat tacctccaat cctttaatat tcaaactata aaaatttgga
     3781 gataaattaa c
//
LOCUS       DBEJAU010000089         3430 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC323 isolate 683620
            SAMN38261939-rid24807223.denovo.089, whole genome shotgun sequence.
ACCESSION   DBEJAU010000089 DBEJAU010000000
VERSION     DBEJAU010000089.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261939
            Sequence Read Archive: SRR26833919
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 3430)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3430)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576303.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576303.1
            Genome Coverage       :: 154x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/19/2025 01:05:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,121
            CDSs (total)                      :: 2,078
            Genes (coding)                    :: 1,943
            CDSs (with protein)               :: 1,943
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 36
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 72 of 135
            Pseudo Genes (incomplete)         :: 63 of 135
            Pseudo Genes (internal stop)      :: 51 of 135
            Pseudo Genes (multiple problems)  :: 46 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3430
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261939-rid24807223.denovo.089"
                     /strain="GPSC323"
                     /isolate="683620"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            complement(<1..622)
                     /locus_tag="ACL29Z_002022"
     CDS             complement(<1..622)
                     /locus_tag="ACL29Z_002022"
                     /inference="COORDINATES: protein motif:HMM:NF012745.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HGR0070266.1"
                     /translation="MEKVSVIVPIYNVEKYLKYSIGGILKQSYKNLEIILVNDGSQDN
                     SLAICEEYSKIDNRIKIISVENGGQGKARNIGLQHSTSDWILFLDADDYYDNNAVEYL
                     VELAERYGSDLVVTPLRVVRDHIQGGNASSIKNEKILNLNKDRLIEEMYYGRLLGATP
                     CGKLYKREILEKWPFPDQLFEDLAIAYKHLMSAKKVAVSNQYYYNYY"
     gene            complement(662..1750)
                     /locus_tag="ACL29Z_002023"
     CDS             complement(662..1750)
                     /locus_tag="ACL29Z_002023"
                     /inference="COORDINATES: protein motif:HMM:NF016228.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent epimerase/dehydratase family
                     protein"
                     /protein_id="HGR0070267.1"
                     /translation="MNLFDISLYKDYVDKSIKNIVGVETLKDKSILITGSTGLICSTV
                     IDQLIILNKNHQFGVKIYACARSEEGLKRRFGNYVDDENIIYVPYDANKDIDFNFTVD
                     YIIHGASNASPDLYISNPVDTMLSNFLGMKNLLDYALKKSVSSIVYVSSSEVYGKTEN
                     HTPYQEDEYGYVNILDVRASYSSSKRATETLCKSYSEQYDVSIKIVRPGHIYGPSLKI
                     TDKRISSAFMYDAIRGQNLVMKSKGEQLRSYCHSLDCASAILTVLLKGQSGDAYNISN
                     KKSIISIREMASIIAEVAGVELLFELPNEVEEKQKNPMDNSSLDSTKLEELGWVGMFE
                     AKEGLESTYKVLDISKIQKISKNIYNID"
     gene            complement(1754..2476)
                     /locus_tag="ACL29Z_002024"
     CDS             complement(1754..2476)
                     /locus_tag="ACL29Z_002024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322619.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-C-methyl-D-erythritol 4-phosphate
                     cytidylyltransferase"
                     /protein_id="HGR0070268.1"
                     /translation="MKIALLTASGIGSRIKQDIPKQFIHVDNKPLIIHTLEKFQNHPN
                     IDEICVVVLKGWEEMLKTYARQFNITKLKYIVNGGETGQLSIYNGLNEIKKNNIDRQV
                     TVLIHDGNRPMVSNEIIDDAFSTYSRYGNAVAAIPCVEVTFVLDNETENHSISSLKRE
                     LLRRTQTPHVYNLDDILELHNRALENGITEVAASCELMKMFGKETYFSMGSEKNLKIT
                     TLDDLEIFKALLKSKKEDWIKD"
     gene            complement(2488..>3430)
                     /locus_tag="ACL29Z_002025"
     CDS             complement(2488..>3430)
                     /locus_tag="ACL29Z_002025"
                     /inference="COORDINATES: protein motif:HMM:NF016357.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="CDP-glycerol glycerophosphotransferase family
                     protein"
                     /protein_id="HGR0070269.1"
                     /translation="TDYHNLNSKYNNLKNVYFINGINGVLKYFTSSFVFYSFGKIPII
                     PSNQRVVQLWHGMFFKDIDKYQKKIVKKEKYYTDVIVTSEMFKELATKVHSCDIGVVK
                     ICGQSRTDVFFNEDKKVTSKYIVWLPTFRQSEKLGYSDTNSEEILIGDYSFEELKKVN
                     SLLKEDNLNMIVKLHPLQTLPANMPNYSNIQILSEEKSRKKNIKLYELLRDSIALITD
                     YSSVFYDYYLLDKPIAFCIRDFEDYNKNRGFIVENPMDYLKGNKIKSLDDMCNFINEI
                     THNVDKFKEERRGFNEKVNKYRDGNNSKRLLEKIGIN"
BASE COUNT         1082 a          630 c          379 g         1339 t
ORIGIN      
        1 gataataatt ataataatat tgatttgata cagctacctt cttagcactc attaaatgtt
       61 tataagctat agccaaatct tcaaaaagtt gatctgggaa aggccatttt tctaatattt
      121 cccttttata taatttacca catggtgtag cccctaagag tcttccgtaa tacatttctt
      181 ctatcaatct atctttattc aagttaagta ttttttcatt cttgattgag gatgcatttc
      241 caccttgaat atgatctctt actactctca atggggttac tactaaatcc gatccatatc
      301 gttcagccag ttctacaaga tattctaccg cattattatc ataataatca tctgcatcta
      361 aaaataaaat ccagtcagaa gttgaatgtt gcaatccaat atttctagct tttccttgtc
      421 ctccattctc aactgaaatt attttaattc tattatctat cttagaatat tcttcacata
      481 tagcaagaga attatcctgg gaaccatcat ttactaaaat aatttctaaa tttttataac
      541 tttgttttag aatacctcct atgctatatt ttaaatattt ttcaacatta tatattggaa
      601 ctattactga aactttttcc attactcctc ctactgatat ttctgctaaa gagactggaa
      661 atcaatctat attgtatata ttcttagata tcttttgaat tttacttata tctaaaactt
      721 tatatgtact ttctaatcct tccttagctt caaacatacc tacccatcct aactcttcca
      781 attttgtact atctaagcta gaattatcca taggattttt ttgtttttct tctacttcat
      841 taggtaattc aaacagtaat tctactccag ctacttcagc tattatagag gccatctctc
      901 ttattgaaat aatagatttt ttatttgaaa tattgtatgc atcgccagac tgacctttca
      961 aaagaactgt caaaattgca cttgcacagt ccaaactatg acaatatgat cgtagttgtt
     1021 ctcctttact tttcattact aaattttgtc ccctgattgc atcatacata aaagcagatg
     1081 aaatcctttt atctgttatt tttaagctag gaccataaat atgacctgga cgaacaattt
     1141 ttatagatac gtcatattgt tcagaataac ttttacacaa tgtctctgtt gctcgctttg
     1201 aacttgaata ggaagctcta acatctaaaa tgtttacata cccatactca tcttcttgat
     1261 acggagtatg attttctgtt tttccatata cttcactgga cgaaacataa actatagaac
     1321 ttactgattt tttcaaagca taatctagta aatttttcat acctaaaaaa ttactaagca
     1381 ttgtatctac aggattacta atgtataaat ctggactggc attactagct ccgtgaatta
     1441 tataatctac agtgaaatta aaatcaatat ctttattagc atcatatgga acataaataa
     1501 tattttcatc atctacataa tttccaaatc gtctttttag tccttcttca ctccttgcac
     1561 aagcataaat tttaactccg aattgatgat tcttattcag tataatcaat tgatcaataa
     1621 cagtcgaaca aataagacct gtcgatcccg taataagaat tgatttatcc tttaaagtct
     1681 caacgccaac tatatttttt atagatttgt ctacataatc cttatataga cttatgtcaa
     1741 ataagttcac agtttaatcc ttaatccaat cttctttttt agatttgaga agagctttaa
     1801 aaatttctaa atcatctaag gtcgttattt ttaaattttt ttcagacccc atagaaaaat
     1861 acgtttcttt tccgaacatc ttcattaatt cacaggaagc tgcaacctca gttattccat
     1921 tttctaaagc tctgttatga agttctagta tatcatctaa attataaaca tgtggtgtct
     1981 gcgttctcct caataactct ctttttaaag aactaataga atgattttca gtctcattat
     2041 ctaatacaaa agtaacctca acacaaggaa ttgcagccac tgcatttcca tatctactat
     2101 acgttgaaaa cgcatcatca atgatttcgt tgcttaccat cggtcgatta ccatcatgaa
     2161 ttaaaacagt cacttgccga tctatattat ttttctttat ttcattaaga ccattataga
     2221 tagataactg accagtttct ccgccattta ctatatattt tagtttcgta atattaaact
     2281 gtctagcata tgttttcaac atttcttccc agccttttaa tactactaca caaatttcat
     2341 caatgtttgg atgattttga aatttttcta gcgtatgaat gatgagtggc ttattgtcaa
     2401 catgtataaa ttgtttcggt atatcttgtt ttattcggct tcctattcct gacgctgtca
     2461 gtagtgcaat tttcataaca gccctcctta gttaattcca attttttcta gcaatctttt
     2521 actattattc ccatctctat atttatttac tttttcatta aatccccttc gttcttcttt
     2581 aaatttatcc acattatgtg taatttcatt tataaaatta cacatatcat ctaatgattt
     2641 gattttattt ccctttaggt agtccatcgg attctctact ataaatcctc tatttttatt
     2701 gtaatcctca aaatctctta tacaaaaagc tattggttta tctaataaat aataatcgta
     2761 aaaaactgaa gaataatctg ttattaatgc tatactgtct cttaacaatt catataactt
     2821 tatattcttt ttcctactct tttcttctga cagtatctga atattactat agttaggcat
     2881 attagcagga agtgtttgaa gcggatgaag cttcactatc atatttagat tgtcttcttt
     2941 taagagacta tttacttttt ttaattcttc aaacgaataa tctcctatca aaatttcttc
     3001 cgaattggta tcactatatc ctaatttctc agattgccta aatgttggca accagacaat
     3061 gtatttggaa gtaacttttt tgtcttcatt aaaaaaaaca tctgttctac tttgaccaca
     3121 gattttaaca actccgatat cacaagaatg aactttagta gctagttctt taaacatctc
     3181 gcttgtaaca attacatcag tgtagtattt ttcttttttg acaatctttt tctgatattt
     3241 atcaatatct ttaaagaaca taccatgcca caattgtact acgcgttgat tagaagggat
     3301 aataggaatt ttcccaaaag agtaaaatac aaagctactt gtaaagtatt ttaatacccc
     3361 attaatgccg tttataaaat atacattttt tagattatta tatttcgaat tcaaattatg
     3421 ataatcagtg
//
LOCUS       DBEJAU010000090         3365 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC323 isolate 683620
            SAMN38261939-rid24807223.denovo.090, whole genome shotgun sequence.
ACCESSION   DBEJAU010000090 DBEJAU010000000
VERSION     DBEJAU010000090.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261939
            Sequence Read Archive: SRR26833919
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 3365)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3365)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576303.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576303.1
            Genome Coverage       :: 154x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/19/2025 01:05:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,121
            CDSs (total)                      :: 2,078
            Genes (coding)                    :: 1,943
            CDSs (with protein)               :: 1,943
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 36
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 72 of 135
            Pseudo Genes (incomplete)         :: 63 of 135
            Pseudo Genes (internal stop)      :: 51 of 135
            Pseudo Genes (multiple problems)  :: 46 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3365
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261939-rid24807223.denovo.090"
                     /strain="GPSC323"
                     /isolate="683620"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            124..978
                     /locus_tag="ACL29Z_002026"
     CDS             124..978
                     /locus_tag="ACL29Z_002026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000220702.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HGR0070270.1"
                     /translation="MTYEYKSHIYLAETALNVKDLASQTAFYQQVIGLEILSQTETES
                     ILGLGGKVLVQLIQAQESGEVREYYGLYHLAILLPTRKALADVLKHLTDLQIPLVGGA
                     DHGYSEAIYLEDLEGNGIELYRDKPVSTWDIREDGRIIGVTEALAAQDIYELGERVEP
                     FILAEGTRMGHIHLSVKDSRKSSQFYQKVLGLENKFSVPGASWIAAGDYHHHLAVNEW
                     RGKGLASHKQGLPGLAYYVIEVAHKKELLTIAQRAQEVDAPIKWMTSSKLEITDSDGI
                     VTRIRLAR"
     gene            1128..1385
                     /locus_tag="ACL29Z_002027"
     CDS             1128..1385
                     /locus_tag="ACL29Z_002027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001845567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-sensitive transcriptional regulator"
                     /protein_id="HGR0070271.1"
                     /translation="MTNSKYITCLKRSEGQLCGIQKMIEGDRDCADIVTQLTAVKSSV
                     ERVIEMIITENLTECINQPLDDSEAQKERLEKAIRYLIKRK"
     gene            complement(1427..1789)
                     /locus_tag="ACL29Z_002028"
     CDS             complement(1427..1789)
                     /locus_tag="ACL29Z_002028"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0070272.1"
                     /translation="MKIKVQTRKLAAGCSKHCFKVVDGTDEVSSKHCFEVVDRTDEVS
                     NHIYGKVKLTWFEEIFEKYKSPHNKTHITKVLMNCTPKVRQKKSNFLGAVHSTPDTMR
                     FFNFKDFLQLLLTPIKLF"
     gene            complement(1843..2139)
                     /locus_tag="ACL29Z_002029"
     CDS             complement(1843..2139)
                     /locus_tag="ACL29Z_002029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000450185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HGR0070273.1"
                     /translation="METSISMADFYGKYQNENLELIDVREAHEFQAGHAPGAKNLPLS
                     TLEQGYKELKPDHEYYVICQGGVRSASTCQFLSSQGLTVTNVEGGMNAWPGQVE"
     gene            complement(2129..2311)
                     /locus_tag="ACL29Z_002030"
                     /pseudo
     CDS             complement(2129..2311)
                     /locus_tag="ACL29Z_002030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000691454.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="CoA-disulfide reductase"
     gene            2360..3124
                     /locus_tag="ACL29Z_002031"
     CDS             2360..3124
                     /locus_tag="ACL29Z_002031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862814.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside phosphorylase"
                     /protein_id="HGR0070274.1"
                     /translation="MIQKHAIPILEFDDNPQAVIMPNHEGLDLQLPKKCVYAFLGEEI
                     DRYAREVGADCVGEFVSATKTYPVYVINYKGEEVCLAQAPVGSAPAAQFMDWLIGYGV
                     EQIISTGTCGVLADIEENAFLVPVRALRDEGASYHYVAPCRYMEMQPEAIAAIEEVLE
                     DRGIPYEEVMTWTTDGFYRETAEKVAYRKEEGCAVVEMECSALAAVAQLRGVLWGELL
                     FTADSLADLDQYDSRDWGSEAFNKALELSLASVHHL"
BASE COUNT          954 a          597 c          804 g         1010 t
ORIGIN      
        1 aaatgattta ctttatatta tcctgaaatg gtgttatttt tgagttatct ggcttgactt
       61 tcttgatgga aattatataa tagttgtaac aataataatt acaactagaa aagaggacca
      121 tttatgacct atgaatacaa gagtcacatt tatttggcag agacagcttt aaatgtaaag
      181 gatttggcca gtcaaacagc cttttatcag caagttattg gtttagaaat cttatctcaa
      241 actgagacag agtccattct aggccttggt ggaaaagtct tggtacagct gattcaagca
      301 caagagagcg gagaagtgag ggaatattat ggtctttacc atttggccat tctcttgccc
      361 acacgcaagg ctttagctga tgtcttgaaa cacctgacag atttacaaat tcctcttgtc
      421 ggcggtgcag accatggtta cagtgaagct atttacttgg aagatttgga gggaaatggc
      481 attgaactct atcgagataa gccagtttcc acatgggata ttcgagaaga tggacgcatt
      541 atcggagtga cggaggctct tgcggcgcag gacatttatg agttggggga aagagtagaa
      601 ccctttatcc tggcagaagg tacaagaatg gggcatattc atctttccgt caaggatagt
      661 cgaaagtcca gccagtttta tcaaaaggtg ttagggctag agaataaatt cagtgtgcct
      721 ggcgctagtt ggattgcggc tggagattac catcatcatt tagcagttaa cgaatggaga
      781 ggaaaaggtc tggcttcgca taagcaaggc ttaccaggtt tagcctacta tgtcatcgaa
      841 gtcgcacata aaaaagaact gttaacgatt gcccaacgag cacaagaagt tgacgcacca
      901 atcaaatgga tgacatcgag caaattggaa atcacagact cagatggcat cgtgacccgt
      961 attcgtttag caaggtaaaa ttaggaattt ttaataagtt ataagtattg ctagtttgct
     1021 ttttgaacgg tctttggtaa cagaactgcg cgagctggat aggtgagaat tttgacaaag
     1081 aagctgatta gagatataat gaagaaaaat cgagcaagga aaaagaaatg acaaattcaa
     1141 agtatattac ttgtttgaaa cgttcagagg gccagttgtg tgggattcaa aagatgattg
     1201 aaggagatcg tgactgtgct gatattgtga cgcaactgac agcagtgaaa tctagtgtag
     1261 agcgcgtgat tgagatgata attaccgaaa atcttactga atgtatcaat cagccactag
     1321 atgattctga agctcaaaag gaacgcttag aaaaggctat ccgatacttg attaaacgga
     1381 aataaatgaa tgttttgaga cgatatgtgc aaaggtctat taactattag aatagtttaa
     1441 tgggagtcaa aagaagttgt aaaaaatctt taaaattaaa aaaacgcata gtatcaggtg
     1501 ttgaatgtac tgcccccaaa aagttagatt ttttctgtct aacttttggg gtgcagttca
     1561 taagaacctt ggtaatatgc gttttattat ggggagattt atacttttcg aaaatctctt
     1621 caaaccaggt caacttcacc ttgccgtaga tatggttact gacttcgtca gttctatcca
     1681 caacctcaaa acagtgtttt gagctgactt cgtcagttcc atccacaacc ttaaaacagt
     1741 gttttgagca gcctgcggct aacttcctag tttgcacttt aattttcatt gagtattact
     1801 tcatcttctc ctgaaattga gtttttgccc agctcctctt gattattcta cttgaccggg
     1861 ccaagcattc ataccacctt ctacgttggt aacggtgagg ccttgggagc tgagaaattg
     1921 gcaggtagat gcagagcgga ctcctccttg acaaatgaca tagtattcat ggtcaggttt
     1981 gagttctttg tagccttgct ctaaggtact taatggaaga tttttggcac ctggtgcatg
     2041 tcctgcttgg aattcatgtg cttcacggac atcgataagt tctagatttt cattttggta
     2101 ttttccataa aagtcagcca tgctgatact agtttccata ttctactcct tctgggttaa
     2161 ccattttgta tagtgaataa gcgccgtcaa ggttttgggc ggtaaatcct gcttgcttga
     2221 ggataggctc tgcgatatag ctgcgcaaac cactgtggca gctgacgatg taggcttgtt
     2281 ttttgtccag ttcatcagct tcctccttga cactttgtca gtttttgata caatagtaca
     2341 aaattagagg aggcaggcta tgattcagaa acatgcgatt cctattttag agtttgatga
     2401 caatcctcag gcggttatca tgcccaatca cgaggggctg gacttgcagt tgccaaagaa
     2461 gtgtgtttat gcatttttag gtgaggagat tgaccgctat gcaagggaag taggggcgga
     2521 ttgtgtcggc gaattcgttt ctgctaccaa gacctatcca gtctatgtca tcaactacaa
     2581 gggtgaggag gtctgtctgg ctcaggctcc tgttggctcc gctccagcag cccagtttat
     2641 ggattggttg attggctatg gtgtggagca gattatctct actgggacct gtggtgtcct
     2701 agctgatata gaggaaaatg cctttctagt ccctgttcgc gctttgcgag atgagggagc
     2761 cagttaccac tatgtggcac cttgtcgtta tatggaaatg cagccagagg ctattgctgc
     2821 tattgaggaa gttttggaag acagagggat tccttatgaa gaagtcatga cctggacgac
     2881 agacggtttt taccgagaaa cggctgaaaa ggtggcttat cgtaaggaag aaggctgtgc
     2941 tgttgtggag atggagtgtt ctgctcttgc ggcagtagct caattgcgtg gggttctctg
     3001 gggtgaattg ttgttcacag cagattctct agcggacttg gaccagtacg acagtcgtga
     3061 ctggggctcg gaagctttta ataaggcgct agaactgagt ttagcaagtg ttcaccacct
     3121 ttagttgtac tggcaaagga tttgttttat cataaaatgt ctagctcata cttttcaaaa
     3181 atatgtttaa acgaggtcac cttcctcttg tcctaggcat gttgaggttg ggaaaaatct
     3241 ttaaaatcag aaaaacgtat catatcaggt gatgaaaatt ttgatactat gcgttttatg
     3301 ttggtaagat ttagagtgag atgaaatgat actcttcgaa aatctcttca aaccaggtca
     3361 gcttc
//
LOCUS       DBEJAU010000091         3298 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC323 isolate 683620
            SAMN38261939-rid24807223.denovo.091, whole genome shotgun sequence.
ACCESSION   DBEJAU010000091 DBEJAU010000000
VERSION     DBEJAU010000091.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261939
            Sequence Read Archive: SRR26833919
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 3298)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3298)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576303.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576303.1
            Genome Coverage       :: 154x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/19/2025 01:05:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,121
            CDSs (total)                      :: 2,078
            Genes (coding)                    :: 1,943
            CDSs (with protein)               :: 1,943
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 36
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 72 of 135
            Pseudo Genes (incomplete)         :: 63 of 135
            Pseudo Genes (internal stop)      :: 51 of 135
            Pseudo Genes (multiple problems)  :: 46 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3298
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261939-rid24807223.denovo.091"
                     /strain="GPSC323"
                     /isolate="683620"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            <1..1326
                     /locus_tag="ACL29Z_002032"
     CDS             <1..1326
                     /locus_tag="ACL29Z_002032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000187211.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HGR0070275.1"
                     /translation="YDIPDTWEWVRFSTLVEIVRGGSPRPIKDYLTSEVDGINWIKIG
                     DTEKGEKYINNVKEKIKKSGLNKTRFVKKGTFLLTNSMSFGRPYILNVDGAIHDGWLA
                     ISNYENSLNKDYLFYILSSNVVYSQFLSLISGAVVKNLNSDKVASILIPLPPLSEQQR
                     IVEAIESALEKVDEYAESYNRLEQLDKEFPDKLKKSILQYAMQGKLVEQDPNDESVEV
                     LLEKIRAEKQKLFEEGKIKKKDLDISIVSQGDDNSYYEEVPCEIPESWEWVRLNDITS
                     YIQRGKSPKYSNIPIYPVIAQKCNQWSGFSIDLARFIDPETVHSYQKERLLRDGDLMW
                     NSTGLGTLGRLAIYHENKNPYGWAVADSHVTVIRVLSGVINCHFIYNFLSSPIVQSVI
                     EEKASGSTKQKELLTKTIKEYLIPLPPLPEQSRIVDKIEQFFAHIDALI"
     gene            1383..2180
                     /gene="psrA"
                     /locus_tag="ACL29Z_002033"
     CDS             1383..2180
                     /gene="psrA"
                     /locus_tag="ACL29Z_002033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000651177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type DNA invertase PsrA"
                     /protein_id="HGR0070276.1"
                     /translation="MKDFELHLKKAGLAENTVRSYLYGVRFFLENYELKMEDLFEYKG
                     YLLDNFKPKTVNLRLQGVNKYLAFIGHDDLKLKFVKVQQKPFLEDVISHADYLFLKRS
                     LKKDGILKWHFVVWFLGATGARVSELIKLKVEHVEIGYFDIYSKGGKIRRLYIPKKLR
                     NSCLSWLESENRRSGYLFLNKFNEPITARGVAQQLKNYADKYKMNPKVIYPHSFRHLF
                     AKNFLAKYNDIALLADLMGHESIETTRIYLRKTATEQQNIVDKIVNW"
     gene            2200..2799
                     /locus_tag="ACL29Z_002034"
     CDS             2200..2799
                     /locus_tag="ACL29Z_002034"
                     /EC_number="3.1.21.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001859489.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006304 - DNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HGR0070277.1"
                     /translation="MTTCYFCDYGSYYGNKDETTSYPIYEIPEAWRYIKFASLVNFRI
                     GKTPPRSEATFWGTEIPWVSISDMPISGYVTNTRESISKLALKSKKIDISPKGTLLMS
                     FKLSIGKVAILDIPATHNEAIISIFPYANKENIIRDYLMIFLPLISTLGDSKDAIKGK
                     TLNSTSISELLIPISNHEEMKRIISKVDLLFQKVSQLFE"
     gene            complement(2747..>3298)
                     /locus_tag="ACL29Z_002035"
     CDS             complement(2747..>3298)
                     /locus_tag="ACL29Z_002035"
                     /EC_number="3.1.21.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015511369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006304 - DNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HGR0070278.1"
                     /translation="IPMNWVVIKIKDIFSINTGLSYKKGDLSINNKGVRIIRGGNIKP
                     LEFSLLDNDYYIDTQFISSEQVYLKHNQLITPVSTSLEHIGKFARIDKDYDGVVAGGF
                     IFQLTPFESSEIISKFLLFNLSSPLFYKQLKAITKLSGQALYNIPKTTLSELLIPLAP
                     FEEQELITQKVEKLFEKVNQLWK"
BASE COUNT         1183 a          482 c          557 g         1076 t
ORIGIN      
        1 tatgatattc ctgatacttg ggagtgggtg aggttttcta cattggttga aattgtcaga
       61 ggtggctctc cacgaccaat caaagattat cttacttctg aagtagatgg aataaattgg
      121 ataaaaatag gtgatactga aaagggtgaa aagtatataa ataatgttaa agaaaaaatc
      181 aaaaaatcag ggcttaacaa aactagattt gtaaaaaaag gtacattttt gttaactaat
      241 tctatgagtt ttggtagacc ttatattttg aatgttgatg gtgcaataca cgatggatgg
      301 ttggctattt cgaactatga aaactcatta aataaagatt acctattcta tattctttca
      361 tcaaatgtag tttattctca atttctatct ctaattagtg gagctgttgt gaaaaacttg
      421 aatagtgata aagttgcttc tattcttatc cctctccccc cactatccga acaacaacga
      481 atagtagaag caatcgaatc agctttagaa aaagtagatg aatatgctga aagttataat
      541 agactagaac agctagataa agaatttcca gataaactaa aaaaatctat tcttcaatat
      601 gctatgcaag gaaaattagt tgaacaagac ccaaatgatg aatcagtcga agttttactt
      661 gaaaaaatac gagcagaaaa acaaaaactc tttgaagaag gcaagattaa aaagaaagat
      721 ttggacattt ctattgtttc ccaaggagat gataactctt attatgagga agtaccttgt
      781 gaaataccag aaagttggga atgggtgagg ttaaacgata taacctccta cattcaaaga
      841 gggaagtctc caaaatattc aaatattcct atataccctg tgattgctca gaaatgtaat
      901 caatggtctg gcttttctat tgacttagca agatttattg atcccgaaac agttcatagt
      961 taccagaaag aaagattact aagagatggt gatttaatgt ggaattcaac aggtctaggt
     1021 acgttaggac gattagctat ttaccatgaa aataaaaatc cttatggctg ggctgttgca
     1081 gatagccatg ttacagttat aagagtctta tcgggagtta ttaattgcca tttcatctat
     1141 aattttcttt cctctcctat tgttcagtca gttattgaag aaaaagcgtc gggtagtaca
     1201 aaacaaaaag aattattaac gaaaactata aaagaatatt taatccccct cccacccctt
     1261 cctgaacaat ccagaatcgt tgataaaatc gaacaatttt tcgcccatat tgacgcacta
     1321 atttagtata atagttttac gtgcggtgga atttctatca aacataagat aggagtttta
     1381 cgttgaaaga ttttgaatta catttgaaga aagctggttt agctgaaaat actgtgcgtt
     1441 cgtaccttta tggtgttcga tttttcttgg agaattacga actcaaaatg gaagatttat
     1501 ttgaatacaa aggatattta ttagacaatt ttaaacctaa aactgtcaat ttgcgactac
     1561 aaggagtaaa taaatatctg gcttttattg gtcatgatga tttgaaatta aaatttgtca
     1621 aagtacagca aaaaccgttt ttagaagatg tcattagcca tgctgattac ctttttctta
     1681 aacgtagttt gaaaaaagat ggtattttaa aatggcattt tgtcgtttgg tttttaggtg
     1741 caactggggc tcgtgtaagt gaacttatta aactaaaagt agagcatgta gaaatcggtt
     1801 attttgacat ttactcaaaa ggtggtaaaa ttcgtagact gtacattcct aaaaaattaa
     1861 gaaatagttg tcttagttgg ttagaatcag aaaatcgccg aagtggttat ttatttttga
     1921 ataaatttaa cgaaccaatt acagcaagag gagttgctca acagttaaaa aattatgctg
     1981 ataaatacaa aatgaatcct aaagtaattt accctcattc ttttaggcat ttatttgcta
     2041 agaatttttt agcgaagtat aatgatattg ccttgcttgc agatttgatg ggacacgaaa
     2101 gtatagaaac tactcgaatt tatctaagga aaacagctac tgaacaacaa aatattgtag
     2161 ataaaattgt taattggtaa aaaataacag gtagtcaaac tgactacctg ttatttttgt
     2221 gattatggct cttattatgg gaacaaagac gaaacaacct cttatcctat atatgaaatc
     2281 ccagaagcat ggagatatat taaatttgct agcctagtta acttcagaat aggaaaaact
     2341 cctccacgca gtgaagctac tttttgggga actgaaatac cctgggtatc tatatcagat
     2401 atgcctatat ctggttatgt aactaatacg agagaatcta tttctaaatt agcattaaaa
     2461 tcaaagaaaa tagacatttc acctaaagga actttattaa tgagctttaa attatctatt
     2521 ggaaaagttg ccatattgga tattcctgcc actcataatg aagccattat atcgatattc
     2581 ccctatgcta ataaagaaaa tattatcaga gattacttaa tgatattttt gccacttatc
     2641 tctactttag gtgattcaaa agatgctatc aaagggaaaa cattaaatag taccagtatc
     2701 tccgaattat taatccctat ttctaatcat gaagagatga aaagaatcat ttccaaagtt
     2761 gatttacttt ttcaaaaagt ttctcaactt tttgagtaat aagttcctgt tcctcaaaag
     2821 gagctaacgg aattaatagc tcgcttagtg tagttttagg aatattatat aaagcttgac
     2881 ctgatagttt agttattgct ttcaattgtt tataaaataa cggagaggac aagttaaata
     2941 atagaaattt tgaaataatc tctgaacttt cgaatggtgt taattggaaa ataaatccac
     3001 cagccacaac accatcatag tctttatcga ttcttgcaaa ctttccaata tgttctaaag
     3061 aggttgatac aggtgttatt agctgattat gttttaaata aacttgctca gaggagatga
     3121 attgtgtatc aatgtagtaa tcattatcca acagagaaaa ttctaaaggc ttaatattac
     3181 caccacgtat aattctaaca cctttattat taatgcttaa atcgcccttc ttgtaagaaa
     3241 gacctgtatt tattgaaaaa atatctttta tttttataac aacccaattc ataggtat
//
LOCUS       DBEJAU010000092         3133 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC323 isolate 683620
            SAMN38261939-rid24807223.denovo.092, whole genome shotgun sequence.
ACCESSION   DBEJAU010000092 DBEJAU010000000
VERSION     DBEJAU010000092.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261939
            Sequence Read Archive: SRR26833919
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 3133)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3133)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576303.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576303.1
            Genome Coverage       :: 154x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/19/2025 01:05:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,121
            CDSs (total)                      :: 2,078
            Genes (coding)                    :: 1,943
            CDSs (with protein)               :: 1,943
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 36
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 72 of 135
            Pseudo Genes (incomplete)         :: 63 of 135
            Pseudo Genes (internal stop)      :: 51 of 135
            Pseudo Genes (multiple problems)  :: 46 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3133
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261939-rid24807223.denovo.092"
                     /strain="GPSC323"
                     /isolate="683620"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            35..1258
                     /locus_tag="ACL29Z_002036"
     CDS             35..1258
                     /locus_tag="ACL29Z_002036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000628995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family transcriptional regulator"
                     /protein_id="HGR0070279.1"
                     /translation="MITKQSAFLQNRATILEFLYRNPATSRTDIVNETGLTPATTTNI
                     IKELSEQSLIYETGDEFSKFSGSGRRRKTISITDNIPYVVGGIEINVLGIFLNLCDLQ
                     GKTLFETEILNEDYPISEINSTITNMIKTAIEYVPLETKLLGFGLSIPGHYNKDSGSI
                     ITNNPIWESFNLLNVIKRFNFPFIVKNNIDCMAIGQYLFNPHNTPDNFIFLHAGLGIY
                     TSFFTKEKIGASKNPYIGEIGHTIVELNGQYCECGKKGCLQTYISDAWLIKHAQLLFK
                     NSQLTVLKSLVKTEKDIHLDTLLTAYNLGDSALRQQIDKGVNLLATSIANLLLINPAD
                     KIYINSQLLNYQPFTHEVRDKIQDQLHFVPFTRNIEIEILPYNKHRGSIGACALAIVA
                     FFIEHSNVLQDIISP"
     gene            2692..2976
                     /locus_tag="ACL29Z_002037"
     CDS             2692..2976
                     /locus_tag="ACL29Z_002037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002923859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0070280.1"
                     /translation="MDWYDYMIQASKQSQFNASHWFRYLRKVIFEDYSYLTNQDVEKL
                     LDSKELTRFQKISLKYAFQEHTPTHKYVISLNKPAKLTNVQKLMEKYKHG"
BASE COUNT         1169 a          565 c          429 g          970 t
ORIGIN      
        1 tgtttaatat aaaataaacc aaaggaggaa acaaatgatt acaaaacaat cagccttttt
       61 acaaaataga gccactatac tggagtttct atatcgaaat ccagcaacat cccgtacaga
      121 tattgttaat gaaacaggac ttactccagc aacaacgact aacatcataa aagagctaag
      181 cgaacagtcc ctcatatacg aaactggtga tgaatttagc aagttttccg gatctggaag
      241 acgtagaaaa actatttcta tcacagataa tattccgtat gttgttggag gtattgaaat
      301 aaacgtccta ggtatctttc tcaatctatg tgacttacaa gggaaaactc ttttcgagac
      361 agaaattttg aatgaagatt atcctatttc agaaatcaat tccaccatta ccaatatgat
      421 aaaaacagct atagagtacg tccctttgga aacaaaatta cttggatttg gcttatcaat
      481 acctggacat tataacaaag actccggaag tatcattaca aacaacccca tatgggaatc
      541 ttttaattta ttaaatgtaa ttaaaagatt caattttcct tttattgtaa aaaataatat
      601 cgattgtatg gctataggac aatacctttt taatccacac aatacccccg ataactttat
      661 tttcctacac gctggattag gtatttacac ttcctttttc acaaaagaaa aaataggagc
      721 ctctaaaaat ccttatatcg gagaaattgg acacaccatt gtcgaattga atgggcaata
      781 ttgtgaatgc ggaaaaaaag gttgtttaca aacatatatt tcggatgctt ggttaatcaa
      841 acacgcccaa ttattattta aaaattccca actaactgta ctaaaaagcc ttgtaaagac
      901 tgaaaaagac attcatttag acaccctttt aacggcttat aatttaggcg actccgcttt
      961 acgtcaacaa attgataaag gagtcaattt attagccact tctattgcaa atctcctcct
     1021 catcaatcct gctgataaaa tctatatcaa cagtcaattg cttaattatc aacctttcac
     1081 tcatgaagtc agggataaaa tccaagacca gctccacttc gttcccttta ctcgtaatat
     1141 agaaattgaa attttacctt acaacaaaca tcgtggaagt ataggagctt gtgcattagc
     1201 tatcgtcgct tttttcatag aacatagcaa tgtattacaa gatattattt caccttaata
     1261 tattagaaat ctatagacct gtttaaatca actataacct gtagtagata tctcgtattt
     1321 agacaatatg aaaacaagac gacttccata taggaaaccg ccttctctct atgttgagtg
     1381 atttatatta aaataacttt tcttctagct gcattttatt attataaaaa cattcatcat
     1441 aacccccaga acttaaataa caatttttat tcaagataca tactcctaga ataaacttta
     1501 tatgaaattc tcatttttgt ttttacaatt ctccttagtt aaatcttgtt taatatatgt
     1561 tttacatata gtatttagcg ccacatagta ctgaactctc tccaaaaacg gttattcctc
     1621 tttgaatagg gcgttatcac aagaaaagca tctccacgtt tcaacttcat atggctcaaa
     1681 aacaatcaat tgatgctaaa acctgtacct agatgtttcg gttcataaaa ccatgaaact
     1741 gtaaaagtgg atgaaattga tagcgatagt caaatcaaga ggcatcataa ctctaaaaag
     1801 tcacaatata taagttcatc ctcggaaaaa tatcattcta attgttgaaa tgcctacatg
     1861 aaaagaaacg tcaaatgctc atgaaacaac gaatacaggt atcaaaacta tgacaaaaca
     1921 aatccctaaa tttactaaag acactgctca actttacacc tgtaaatggt tgttgtataa
     1981 taaagttaca aagatgtacg accacactgt tgtaaatcat agtgttcgcg aatatattac
     2041 tgatagcatt tctacaaata caagtaaaga gagcggatga gattcaaacg aaatatgtca
     2101 gtgctttggc attcctagcc ttcatatcat ttaaagaatt ctatagacaa aattttttcc
     2161 aatacagaca ctcgtaacaa ctgcttcatt tttctaccaa catatttagg aacaggataa
     2221 gatacaagag tattaatcca tagctcagtt ctataccaat ctaagacaaa taagctaaaa
     2281 aaacgattga taataagcaa atagattcca aattttctct atctgctcat tttaataaac
     2341 aatactagtg taactatcct tccagtcaga aacttgtcaa atcacaccga aaactcttct
     2401 aaaatttatc tcgttaggca atcaagcaaa aactcgacga tagtacaaac attatcatac
     2461 agaattgact gcctaaatta tatactttag taaggttttc ggataagaaa aaaggttcat
     2521 tttacatttc taaacattct tttctaagat gaaaaacaga atttttcgat tgtgatttaa
     2581 agcaacaaga agattttcag tatcatccta tagatacgag ctaattaaga aaaactacat
     2641 ttttgaatat aaactacaat aatataaact aaattttata ggaggaagac aatggattgg
     2701 tacgattata tgatacaggc atccaaacaa tcacaattca acgcaagcca ttggtttcgc
     2761 tatttgcgaa aagttatttt tgaagactat tcttatttaa caaaccaaga tgtagaaaag
     2821 ttgctagact ccaaagaact aacccgtttt caaaaaatta gcttgaagta tgcctttcaa
     2881 gagcatactc caactcataa atatgtgatt tcattaaata aacctgctaa gttaaccaat
     2941 gttcaaaaat tgatggagaa atacaaacat ggataaaatg aaaccggtct tccaagccct
     3001 aaataagaaa ttaattcagg aaaatctgac tttaacaatt atggttatgt cttagaatat
     3061 catggtttac gtgccacaca agatgttgat gcttttatgg ctctataata tttgtagtgg
     3121 ataaatcccc tat
//
LOCUS       DBEJAU010000093         3085 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC323 isolate 683620
            SAMN38261939-rid24807223.denovo.093, whole genome shotgun sequence.
ACCESSION   DBEJAU010000093 DBEJAU010000000
VERSION     DBEJAU010000093.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261939
            Sequence Read Archive: SRR26833919
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 3085)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3085)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576303.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576303.1
            Genome Coverage       :: 154x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/19/2025 01:05:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,121
            CDSs (total)                      :: 2,078
            Genes (coding)                    :: 1,943
            CDSs (with protein)               :: 1,943
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 36
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 72 of 135
            Pseudo Genes (incomplete)         :: 63 of 135
            Pseudo Genes (internal stop)      :: 51 of 135
            Pseudo Genes (multiple problems)  :: 46 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3085
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261939-rid24807223.denovo.093"
                     /strain="GPSC323"
                     /isolate="683620"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            <1..185
                     /locus_tag="ACL29Z_002038"
     CDS             <1..185
                     /locus_tag="ACL29Z_002038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001818644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_process: GO:0006302 - double-strand break repair
                     [Evidence IEA]"
                     /codon_start=3
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HGR0070281.1"
                     /translation="KYENRTVSFAISSKGEKMKVENISYRVDHRILFDNISFDTLSSG
                     VTLITGKNGTGKSTLL"
     gene            complement(307..473)
                     /locus_tag="ACL29Z_002039"
                     /pseudo
     CDS             complement(307..473)
                     /locus_tag="ACL29Z_002039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_086558122.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(551..1861)
                     /locus_tag="ACL29Z_002040"
     CDS             complement(551..1861)
                     /locus_tag="ACL29Z_002040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000581523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SLC13 family permease"
                     /protein_id="HGR0070282.1"
                     /translation="MIHLIMISAIALAIGIGYRTKINIGLLAIAFSYLIATTLMGLSP
                     KELLHFWPTSLFFTIFSVSLFYNVAITNGTLDVLAQHILYRTRTYPNALYMILYLMAT
                     LLSALGAGFFTTMAVCCPLAITLCQKADKHPLIGAQAVNWGASGGANLITSSSGIVFQ
                     GLFKQMGWEEQAFSLGNHIFIVSIIYPLIVLLLLSCYSHYSKGRTNSSLTIDQPPLLS
                     KVQRQTTLLMINSMVLVWLFPLLHLIFPNIAWIATYQKTFDIGFVSILMVCLALRLKL
                     GKQEAILAKVPWATIIMLCGMSLLMSLAVKSGLVTLIGHLMTTTIPHFWLPLFFCVIA
                     GVMSLFSSTLSVVVPALFPIIAIISAQNPQIDIHLLTTATVIGALSTNISPFSSAGSL
                     IQLSLPNIEERGLAFKKQIILGVPISLSLGLLTTWILILLASLS"
     gene            2098..2970
                     /gene="nadC"
                     /locus_tag="ACL29Z_002041"
     CDS             2098..2970
                     /gene="nadC"
                     /locus_tag="ACL29Z_002041"
                     /EC_number="2.4.2.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000022746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004514 - nicotinate-nucleotide
                     diphosphorylase (carboxylating) activity [Evidence IEA];
                     GO_process: GO:0009435 - NAD biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carboxylating nicotinate-nucleotide
                     diphosphorylase"
                     /protein_id="HGR0070283.1"
                     /translation="MSIISTDLTPFQIDDTLKAALREDVHSEDYSTNAIFDHHGQAKV
                     SLFAKEAGVLAGLTVFKRVFTLFDAEVTFQNPHQFKDGDRLTSGDLVLEIIGSVRSLL
                     TCERVALNFLQHLSGIASMTAAYVEALDDDCIKVFDTRKTTPNLRLFEKYAVRVGGGY
                     NHRFNLSDAIMLKDNHIAAVGSVQKAIAQARAYAPFVKMVEVEVESLAAAEEAAAAGA
                     DIIMLDNMSLEQIEQAITLIAGRSRIECSGNIDMTTISRFRGLAIDYVSSGSLTHSAK
                     SLDFSMKGLTYLDV"
BASE COUNT          956 a          512 c          700 g          917 t
ORIGIN      
        1 aaaagtatga aaacagaact gtttcttttg ctattagttc aaaaggagaa aaaatgaaag
       61 tagaaaatat ttcgtatagg gtggatcatc gtatattgtt tgataatatt tcttttgata
      121 ctttgagttc aggcgtgaca ttaattactg gtaaaaatgg tacaggaaag tcaactttac
      181 tatagtagat tgaaactaga atagtacaca tctacttcta aaatattgtt agaaatcgat
      241 ttgactatcc tgatctattt gtcctggtct tatttcattt cactatattt caaattgagt
      301 atgacgaagt gcgctcccat gtcctgggaa cgcactttct tcatattttt catattcttg
      361 aatccatcga taaagactat tgggatgaat ttttaaagtt gaactaatca tttttacagg
      421 atgagattta cagcagagag tttgaaggct ttatcaaagg tttttcttgg cataatgact
      481 tttcctcgtt tccacttaat tttgtgtcta ctttattata ccaagtccac ccttaagtta
      541 gataataaat ctaacttaag gaagctagaa ggatgagaat ccaggtggtc aagagtccca
      601 aacttaagct gatggggaca cccagaataa tttgcttttt gaaggcaagg ccacgttcct
      661 ctatattggg aagtgagagt tgaatgagag aaccagctga tgaaaagggt gagatattag
      721 tagatagagc gccaataacg gtggctgttg tgagtaagtg aatatcaatc tgaggatttt
      781 gagcactgat gatagcaatg atgggaaaga gggctggaac tacaacggat agggtggaac
      841 taaagagtga catcactccg gctatcacac aaaagaacag aggtaaccag aaatgaggaa
      901 tggttgttgt catgaggtgc cctatcagtg tgactaaacc tgacttgacc gctagagaca
      961 ttagtaagct catgccgcag agcatgataa ttgtagccca gggaacctta gctaaaatgg
     1021 cttcttgctt ccctaatttg agccttaagg cgaggcagac catgagtatt gagacaaagc
     1081 caatatcaaa tgttttttga taagtagcta tccaggcgat gtttgggaaa atgagatgca
     1141 acaagggaaa aagccaaacc aaaaccatgc tgttgatcat gagcaaggtg gtttgtcttt
     1201 gaaccttgct gaggagtggt ggttggtcaa tagtcaagga tgagtttgtt cttcccttac
     1261 tatagtgact gtaacaggat aataaaagca agacgatgag tgggtagata atgctgacga
     1321 taaagatatg attgccaagt gaaaaagctt gctcttccca tcccatttgc ttaaacaggc
     1381 cttgaaagac aatgcctgag ctactggtta tcaaattagc ccctcctgaa gctccccaat
     1441 tgacggcttg agctccaatc aaagggtgtt tgtccgcttt ttgacagagg gtaatcgcta
     1501 gaggacagca aacggccata gtagtgaaaa atccagcacc taaagcagac aaaagggttg
     1561 ccatcaggta taaaatcatg tagagggcgt tagggtaggt gcgtgtgcgg tagagaatgt
     1621 gttgagccaa aacatcaaga gtaccgttag ttattgcaac gttataaaag agagagacgc
     1681 taaaaatggt aaaaaagagt gaggttggcc aaaaatgaag aagttctttg gggcttaatc
     1741 ccatgagagt ggttgcgatg aggtaagaaa aagcaatagc cagcaggcca atattgattt
     1801 tggtgcggta accaattcca atggctagag caatggcgct aatcattatt aaatgaatca
     1861 ttgaattgtc ctttcagtta gaatatggaa ataggttggc aattttggcg ctcaaaagac
     1921 cacctgtttc ctattggtac ttgactatta tacacaaaaa aaatacaatt gtcttgacaa
     1981 ttgtattgac acttgttaga attaaaaatg aggtattcag gtttgtgatt tcctatggaa
     2041 gttaatagtg attgcctcta gtgcttacaa gtgatattaa aaatagagga cctagtgatg
     2101 tcaatcattt caactgattt aacccctttt caaatagatg atacattgaa agcagccttg
     2161 cgagaagatg ttcattccga agattacagt accaatgcca tttttgatca tcatggccaa
     2221 gccaaggtgt cgctttttgc caaggaagct ggtgttttag cggggctaac cgtttttaaa
     2281 agggttttta ccctatttga tgccgaggtg accttccaga atcctcatca atttaaggat
     2341 ggggatcgtt tgactagtgg cgatttggtt ttagaaatca taggctcggt gagaagtctc
     2401 ttaacatgtg aacgcgttgc cttgaatttt ttacaacatt tatcagggat tgcttcgatg
     2461 acagctgctt atgtagaagc cttagacgat gattgcatta aggtatttga tactcgaaaa
     2521 actactccta atttacgtct ttttgagaaa tatgccgtga gagttggcgg tggctataat
     2581 catcgcttta atttatcaga tgctatcatg ctaaaagaca atcacattgc ggcagtaggt
     2641 agtgttcaaa aggcaattgc tcaagcgcgt gcctatgccc cttttgtgaa aatggtagag
     2701 gtggaagtgg aaagccttgc tgctgccgaa gaagctgcgg cggcgggtgc tgatattatc
     2761 atgttggata atatgtcatt ggaacagatt gaacaggcca ttaccctaat tgcaggacgt
     2821 tctcggattg aatgttctgg aaatattgat atgaccacta ttagccgttt tcgtggttta
     2881 gcgattgatt acgtctccag tggtagttta acccatagtg ctaagagtct tgatttttcc
     2941 atgaagggtt taacctacct tgatgtctaa gttgtaaaat aaactaactt tttaaaggat
     3001 gtctttcctc tagaacgagt tttatgtcag atagtttaaa cgcctcttca aatatagtaa
     3061 aatgaaccaa aaatagtaca caatg
//
LOCUS       DBEJAU010000094         2980 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC323 isolate 683620
            SAMN38261939-rid24807223.denovo.094, whole genome shotgun sequence.
ACCESSION   DBEJAU010000094 DBEJAU010000000
VERSION     DBEJAU010000094.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261939
            Sequence Read Archive: SRR26833919
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 2980)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2980)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576303.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576303.1
            Genome Coverage       :: 154x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/19/2025 01:05:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,121
            CDSs (total)                      :: 2,078
            Genes (coding)                    :: 1,943
            CDSs (with protein)               :: 1,943
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 36
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 72 of 135
            Pseudo Genes (incomplete)         :: 63 of 135
            Pseudo Genes (internal stop)      :: 51 of 135
            Pseudo Genes (multiple problems)  :: 46 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2980
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261939-rid24807223.denovo.094"
                     /strain="GPSC323"
                     /isolate="683620"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            381..620
                     /locus_tag="ACL29Z_002042"
     CDS             381..620
                     /locus_tag="ACL29Z_002042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000770310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0070284.1"
                     /translation="MKLLDCILDYQERFNGKTCQVSTNYKYLEIFKVNFCLTDLHHLF
                     DLHKITRDYASQTKPAIQDGVFILEDFRNILCTMM"
     gene            639..884
                     /locus_tag="ACL29Z_002043"
     CDS             639..884
                     /locus_tag="ACL29Z_002043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000058767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0070285.1"
                     /translation="MSLSAISSISKLASCCIVAKDLSKNTMKLDVIFFEDKNKRSAVL
                     GLRRDKSGVFKPVTLHFTSAKKYAKVRKTDVKEMKWL"
     gene            1173..>2980
                     /gene="pspA"
                     /locus_tag="ACL29Z_002044"
     CDS             1173..>2980
                     /gene="pspA"
                     /locus_tag="ACL29Z_002044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001035362.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal surface protein A"
                     /protein_id="HGR0070286.1"
                     /translation="MNKKKMILTSLASVAILGAGFVTSQPTFVRAEESPQVVEKSSLE
                     KKYEEAKAKADTAKKDYETAKKKAEDAQKKYEDDQKRTEEKARKEAEASQKLNDVALV
                     VQNAYKEYREVQNQRSKYKSDAEYQKKLTEVDSKIEKARKEQQDLQNKFNEVRAVVVP
                     EPNALAETKKKAEEAKAEEKVAKRKYDYATLKVALAKKEVEAKELEIEKLQYEISTLE
                     QEVATAQHQVDNLKKLLAGADPDDGTEVIEAKLKKGEAELNAKQAELAKKQTELEKLL
                     DSLDPEGKTQDELDKEAEEAELDKKADELQNKVADLEKEISNLEILLGGADSEDDTAA
                     LQNKLATKKAELEKTQKELDAALNELGPDGDEEETPAPAPQPEQPAPAPKPEQPAPAP
                     KPEQPAPAPKPEQPAPAPKPEQPAPAPKPEQPAKPEKPAEEPTQPEKPATPKTGWKQE
                     NGMWYFYNTDGSMAIGWLQNNGSWYYLNANGAMATGWVKDGDTWYYLEASGAMKASQW
                     FKVSDKWYYVNSNGAMATGWLQYNGSWYYLNANGDMATGWLQYNGSWYYLNANGDMAT
                     GWAKVNGSWYYLNANGAMATGWAKVNGSWYYLNANGS"
BASE COUNT         1112 a          488 c          617 g          763 t
ORIGIN      
        1 agtgagatat attgactttt gaaaaaaatg tcataattga gttgggataa acctaaaagt
       61 aatatagtag attgaatctg gaatagtccg ttatgactgt taaaatattt ctagaaatta
      121 atttgacttt cctaatcgat ttgttcacat cttgtttcaa tctactatac tttctcgtta
      181 aaccgttcgg taattcatgg tgacatggac acatagtagt aagcacacta tgtggcttgg
      241 cagatctaaa aactgttccc ttgcgataag cctaataagc acaacatagg gagttagaga
      301 agccgactct aatcaaccac tttgggcagt agtggtaact gccccgtgct ttttattttg
      361 agaaaatatg gagtttgtcg ttgaaattac ttgattgtat tttggattat caagaaagat
      421 tcaatggaaa aacatgtcaa gtatcaacga attataagta tttagagatt ttcaaagtga
      481 atttttgctt gactgattta catcatttat ttgacttaca caaaatcaca cgagattatg
      541 ctagtcaaac aaaacctgct attcaagatg gtgtttttat tttagaagat tttagaaata
      601 tcctatgtac aatgatgtaa tcgaaaggat atctttatgt gagtttatcg gcgatatctt
      661 ctatatctaa gctagcaagt tgttgcatcg tagctaagga tttatctaaa aatactatga
      721 aattggacgt catatttttt gaggataaaa ataaaagatc cgcagtttta ggtttacgaa
      781 gagacaaaag cggagtattt aaaccagtta ctctacattt tacaagcgct aagaaatatg
      841 ctaaagttcg taaaacagat gtgaaagaaa tgaaatggct ataaagattg tccgcaggct
      901 taagcttgcg ttttttgttg tttaacgaaa ttaaaaaaca agctctctca tcggaaatgt
      961 ttttatagga atgaaggaag atgatgctat gtttaaaaag agaatcgaaa agggcaaaag
     1021 tagtatcttt atctattttt tggagtagaa gcttatgata tagaaatttg taataaaaat
     1081 gtaatataaa acatttgaca aatatttacg gggggagtat acttaatata attatagtct
     1141 aaaaatgact atcagaaaag aggtaaattt agatgaataa gaaaaaaatg attttaacaa
     1201 gtctagccag cgtcgctatc ttaggggctg gttttgttac gtctcagcct acttttgtaa
     1261 gagcagaaga atctccacaa gttgtcgaaa aatcttcatt agagaagaaa tatgaggaag
     1321 caaaagcaaa agctgatact gccaagaaag attacgaaac ggctaaaaag aaagcagaag
     1381 acgctcagaa aaagtatgaa gatgatcaga agagaactga ggagaaagct cgaaaagaag
     1441 cagaagcatc tcaaaaattg aatgatgtgg cgcttgttgt tcaaaatgca tataaagagt
     1501 accgagaagt tcaaaatcaa cgtagtaaat ataaatctga cgctgaatat cagaaaaaat
     1561 taacagaggt cgactctaaa atagagaagg ctaggaaaga gcaacaggac ttgcaaaata
     1621 aatttaatga agtaagagca gttgtagttc ctgaaccaaa tgcgttggct gagactaaga
     1681 aaaaagcaga agaagctaaa gcagaagaaa aagtagctaa gagaaaatat gattatgcaa
     1741 ctctaaaggt agcactagcg aagaaagaag tagaggctaa ggaacttgaa attgaaaaac
     1801 ttcaatatga aatttctact ttggaacaag aagttgctac tgctcaacat caagtagata
     1861 atttgaaaaa acttcttgct ggtgcggatc ctgatgatgg cacagaagtt atagaagcta
     1921 aattaaaaaa aggagaagct gagctaaacg ctaaacaagc tgagttagca aaaaaacaaa
     1981 cagaacttga aaaacttctt gacagccttg atcctgaagg taagactcag gatgaattag
     2041 ataaagaagc agaagaagct gagttggata aaaaagctga tgaacttcaa aataaagttg
     2101 ctgatttaga aaaagaaatt agtaaccttg aaatattact tggaggggct gattctgaag
     2161 atgatactgc tgctcttcaa aataaattag ctactaaaaa agctgaattg gaaaaaactc
     2221 aaaaagaatt agatgcagct cttaatgagt taggccctga tggagatgaa gaagaaactc
     2281 cagcgccggc tcctcaacca gagcaaccag ctcctgcacc aaaaccagag caaccagctc
     2341 cagctccaaa accagagcaa ccagctcctg caccaaaacc agagcaacca gctcctgcac
     2401 caaaaccaga gcaaccagct ccagctccaa aaccagagca accagctaag ccggagaaac
     2461 cagctgaaga gcctactcaa ccagaaaaac cagccactcc aaaaacaggc tggaaacaag
     2521 aaaacggtat gtggtatttc tacaatactg atggttcaat ggcaataggt tggctccaaa
     2581 acaacggttc atggtactac ctaaacgcta acggcgctat ggcaacaggt tgggtgaaag
     2641 atggagatac ctggtactat cttgaagcat caggtgctat gaaagcaagc caatggttca
     2701 aagtatcaga taaatggtac tatgtcaaca gcaatggcgc tatggcgaca ggctggctcc
     2761 aatacaatgg ctcatggtac tacctcaacg ctaatggtga tatggcgaca ggatggctcc
     2821 aatacaacgg ttcatggtat tacctcaacg ctaatggtga tatggcgaca ggctgggcta
     2881 aagtcaacgg ttcatggtac tacctaaacg ctaacggtgc tatggctaca ggttgggcta
     2941 aagtcaacgg ttcatggtac tacctaaacg ctaacggttc
//
LOCUS       DBEJAU010000095         2937 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC323 isolate 683620
            SAMN38261939-rid24807223.denovo.095, whole genome shotgun sequence.
ACCESSION   DBEJAU010000095 DBEJAU010000000
VERSION     DBEJAU010000095.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261939
            Sequence Read Archive: SRR26833919
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 2937)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2937)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576303.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576303.1
            Genome Coverage       :: 154x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/19/2025 01:05:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,121
            CDSs (total)                      :: 2,078
            Genes (coding)                    :: 1,943
            CDSs (with protein)               :: 1,943
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 36
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 72 of 135
            Pseudo Genes (incomplete)         :: 63 of 135
            Pseudo Genes (internal stop)      :: 51 of 135
            Pseudo Genes (multiple problems)  :: 46 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2937
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261939-rid24807223.denovo.095"
                     /strain="GPSC323"
                     /isolate="683620"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            complement(63..524)
                     /locus_tag="ACL29Z_002045"
     CDS             complement(63..524)
                     /locus_tag="ACL29Z_002045"
                     /inference="COORDINATES: protein motif:HMM:NF013842.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS630 transposase-related protein"
                     /protein_id="HGR0070287.1"
                     /translation="MGKERRKQGNLERKKRVVKKRKIPLEELKAFVEAHPDAFLREIA
                     ARFDCALPSVWAVLKQIKVILKKTTSFREQKPEKVSEFLDILDNLKDLPVLYIDETGI
                     DRYLYRPYAGAPRGEKVYGKISGRRFERTNEVEQKLNGSFLIRYIDSQIRE"
     gene            complement(491..592)
                     /locus_tag="ACL29Z_002046"
     CDS             complement(491..592)
                     /locus_tag="ACL29Z_002046"
                     /inference="COORDINATES: protein motif:HMM:NF013842.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0070288.1"
                     /translation="MKGGHRHVEAAKVFDVGVRTLFTWEKKDVNKGT"
     gene            901..1281
                     /locus_tag="ACL29Z_002047"
     CDS             901..1281
                     /locus_tag="ACL29Z_002047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000221621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HGR0070289.1"
                     /translation="MTYLEKWFDFNRRQKEIESLLEETIAQQSEQSLTLKEFYLLYYL
                     DLAEEKSLRQIDLPDKLHLSPSAVSRMVARLEAKNCGLLSRMCCHQDRRSSFICLTND
                     GQKTLASLQKTVEESLEAGLDFLI"
     gene            1380..1601
                     /locus_tag="ACL29Z_002048"
     CDS             1380..1601
                     /locus_tag="ACL29Z_002048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4649 family protein"
                     /protein_id="HGR0070290.1"
                     /translation="MIEITYIDASKNERTVTFESYEDFERSQQACLIGVADYYPVQKL
                     TYKGHNLDYHGTYGDIFFYLMKQDLSQYN"
     gene            1618..1932
                     /gene="trxA"
                     /locus_tag="ACL29Z_002049"
     CDS             1618..1932
                     /gene="trxA"
                     /locus_tag="ACL29Z_002049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003004519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015035 - protein-disulfide reductase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin"
                     /protein_id="HGR0070291.1"
                     /translation="MAKAITDATFEQETKDGLVLVDFWATWCGPCRMQGPILDKLSEE
                     LSEDVLKIVKMDVDENPNTARAFGIMSIPTLLFKKDGQVVKQVAGVHTAEQIKAIIAE
                     LS"
     gene            2238..2771
                     /gene="queF"
                     /locus_tag="ACL29Z_002050"
     CDS             2238..2771
                     /gene="queF"
                     /locus_tag="ACL29Z_002050"
                     /EC_number="1.7.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000828792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0033739 - preQ1 synthase activity
                     [Evidence IEA];
                     GO_function: GO:0046857 - oxidoreductase activity, acting
                     on other nitrogenous compounds as donors, with NAD or NADP
                     as acceptor [Evidence IEA];
                     GO_process: GO:0008616 - queuosine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="preQ(1) synthase"
                     /protein_id="HGR0070292.1"
                     /translation="MKRQLALVVFSGGQDSTTCLFWVMQHYETVEAVTFAYGQRHHLE
                     IQITREIAKEQGIRHHILDMSLLGQITAQPDFATIHISYIPDKLCVESKSLKLYLFSY
                     RNHGDFHENCINTIGKDLVNLLDPRYLEVWGKFTPRGGISIDPYYNYGKQGTKYEGLA
                     EQRLFQHDLYPEKIDNR"
BASE COUNT          912 a          613 c          556 g          856 t
ORIGIN      
        1 caaatgagta taaatcagct aatttttggt ttatattcct atttttatgc ataattattc
       61 tttcattctc taatttgtga atcaatatat ctgattagaa aactaccatt gagtttttgc
      121 tccacctcat tagtccgctc aaaacgccgt ccgctaatct tgccatagac tttctcccct
      181 ctaggagccc ctgcataagg acgatagagg tagcggtcga ttcccgtttc gtcaatatat
      241 aggactggta aatcttttag gttatccaaa atatcaagaa actcagaaac tttctcaggc
      301 ttttgttccc taaaactggt cgtctttttt aaaatgacct taatctgctt taaaactgcc
      361 catacggagg gcaaagcaca atcaaaacgg gccgcaattt cccgtaaaaa agcgtctgga
      421 tgagcctcta caaaggcttt caattcttct aaagggatct tacgcttttt gacgactcgc
      481 tttttccgct ctaagttccc ttgtttacgt ctttcttttc ccacgtgaag agagttctga
      541 cgccgacatc aaaaactttg gccgcctcga catgtctgtg ccctccttta atggaatcta
      601 atgctccttg tttaaaatca gtactatatg catagcttta ttagaccatg cttattttaa
      661 actaagcaac tatagataga gaaatgaaat aaaatctgaa ttcgaatgtg ataaggagtt
      721 agaaattgaa acaataggat tcccccatta ttcacacaaa aataaaacca ctaaaaaaca
      781 gagcttgcca gcattcttga aaagtagtat aattattgca tgcgcaatca tcttgtgacg
      841 cagagactgc ccgttaatgg actttcttct atttatgact ctaaaaagaa aggagacact
      901 atgacctatt tggaaaaatg gtttgacttc aatcggcgtc agaaagaaat tgaaagtctc
      961 ttggaagaga ccattgccca acagagcgag caaagtctga ccttgaaaga gttctacctg
     1021 ctctactatc tggacttggc tgaagaaaaa tctctacgcc agattgacct gccagataag
     1081 cttcatctga gcccgagcgc agtttctagg atggtggctc gcttggaagc taaaaattgc
     1141 ggtctactca gtcgcatgtg ttgccatcaa gatagacgct ctagttttat ctgcctgaca
     1201 aatgatgggc aaaagacact ggcctcgcta caaaagactg tcgaagaaag cttggaagca
     1261 ggtttggatt tcttgattta agatgatttt aaaaaaagtt gcgtgcgcaa tcatttttct
     1321 tgacattctc ttttataagg agtaaaataa agttagcatt aaacaaagga gttttaaaca
     1381 tgattgaaat tacctatata gatgccagca agaacgaaag aactgtgact ttcgagtctt
     1441 atgaagactt tgaacgttcg caacaagctt gccttatcgg cgtcgcagac tactaccctg
     1501 tccaaaaatt aacttacaag ggtcataatt tggactacca tgggacttat ggagatatct
     1561 tcttctatct catgaaacaa gatttaagcc aatataacta aaaaaaggag aaatacaatg
     1621 gcaaaagcaa ttacagatgc aacattcgaa caagaaacaa aagacggttt ggtcttagta
     1681 gacttctggg caacttggtg tggtccatgt cgtatgcaag gtccaatctt ggacaaattg
     1741 tctgaagaac tttcagaaga tgtcttgaaa atcgttaaaa tggacgttga tgaaaatcca
     1801 aacacagctc gtgcttttgg aatcatgtct attccaactc ttctcttcaa aaaagacggc
     1861 caagttgtca aacaagttgc aggtgttcac acagcagaac aaatcaaggc catcattgct
     1921 gaattgagct aatcaaacga gagaccaagt actttctttg gtctcttttt tcttgccctt
     1981 tgccattttt caaaaaatat gctagactat agtagattga aactagaata gtacacctct
     2041 acttctaaaa cattgttaga aatcgatttg actgtcctga tcgatttgtc ctgttcttat
     2101 ttcattttac tatataagta gaatattacg atgtttggga tatgccatcg ctaaaaaaac
     2161 ctcgatttgg tattttttag ctccctaatg ggagcttttt gcgtgctctg aacatttccc
     2221 attttggaag gagtactatg aaacgtcaat tagccttggt cgtctttagt ggtggtcaag
     2281 attcaacaac ctgccttttc tgggtcatgc aacactatga aacagtcgaa gctgtcacct
     2341 ttgcctacgg ccaacgtcat cacctcgaaa ttcaaattac tagagaaatc gctaaggaac
     2401 agggcattcg tcaccatatc ctcgatatgt ctctgctggg acaaatcact gctcagccag
     2461 actttgcgac gattcatatt tcctacattc ctgacaagct ctgtgtcgag tcaaaatccc
     2521 tcaaactata tctatttagc taccgaaacc acggagattt ccacgaaaac tgtatcaaca
     2581 ccatcgggaa agacttggtc aacttgctag accctcgcta tttagaagtc tggggaaaat
     2641 tcactccgcg cggtggcatt tcaatcgacc cctactacaa ctacggtaag caaggaacta
     2701 agtatgaggg cttggcagaa caacgcctct tccaacacga cctttatcca gagaaaattg
     2761 acaaccgcta aagtcatact caatgaaaat caaagagcaa actaggaagt tagccgcagg
     2821 ttgctcaaag cactgttttg aggttgtgga tagaactgac gaagtcagat caaaacactg
     2881 ttttgaggtt gtggatagaa ctgacgaagt cagatcaaaa cactgttttg aggttgt
//
LOCUS       DBEJAU010000096         2933 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC323 isolate 683620
            SAMN38261939-rid24807223.denovo.096, whole genome shotgun sequence.
ACCESSION   DBEJAU010000096 DBEJAU010000000
VERSION     DBEJAU010000096.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261939
            Sequence Read Archive: SRR26833919
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 2933)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2933)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576303.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576303.1
            Genome Coverage       :: 154x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/19/2025 01:05:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,121
            CDSs (total)                      :: 2,078
            Genes (coding)                    :: 1,943
            CDSs (with protein)               :: 1,943
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 36
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 72 of 135
            Pseudo Genes (incomplete)         :: 63 of 135
            Pseudo Genes (internal stop)      :: 51 of 135
            Pseudo Genes (multiple problems)  :: 46 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2933
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261939-rid24807223.denovo.096"
                     /strain="GPSC323"
                     /isolate="683620"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            366..1652
                     /locus_tag="ACL29Z_002051"
     CDS             366..1652
                     /locus_tag="ACL29Z_002051"
                     /EC_number="3.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000169115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:1901576 - obsolete organic substance
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="U32 family peptidase"
                     /protein_id="HGR0070293.1"
                     /translation="MTKTLKRPEVLSPAGTLEKLKVAVQYGADAVFIGGQAYGLRSRA
                     GNFTFEQMEEGVQFAAKYGAKVYVAANMVMHEGNEAGAGEWFRKLRDIGIAAVIVSDP
                     ALIMIAATEAPGLEIHLSTQASATNYETLEFWKELGLTRVVLAREVSMEELAEIRKRT
                     DVEIEAFVHGAMCISYSGRCTLSNHMSMRDANRGGCSQSCRWKYDLYDMPFGKERKSL
                     QGEIPEEFSMSAVDMSMIDHIPDMIENGVDSLKIEGRMKSIHYVSTVTNCYKAAVDAY
                     LESSEKFEAIKQDLVDEMWKVAQRELATGFYYGIPSENEQLFGARRKIPEYKFVAEVV
                     SYDDAAQTATIRQRNVINEGDQVEFYGPGFRHFETYIEDLHDAKGNKIDRAPNPMELL
                     TIKVPQPVQSGDMVRALKEGLINLYKEDGTSVTVRA"
     gene            1667..1978
                     /locus_tag="ACL29Z_002052"
     CDS             1667..1978
                     /locus_tag="ACL29Z_002052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="CHY zinc finger protein"
                     /protein_id="HGR0070294.1"
                     /translation="MIEAQGFLVDKQTRCIHYHSKLDIIALQCYDCKKYYACYRCHDS
                     LENHPFEPYPLSLIQDKPILCGVCLKLLTYKQYKESLSCLFCFSRFNPGCQNHKERYF
                     K"
     gene            2224..2933
                     /locus_tag="ACL29Z_002053"
                     /pseudo
     CDS             2224..2933
                     /locus_tag="ACL29Z_002053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000169115.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="U32 family peptidase C-terminal
                     domain-containing protein"
BASE COUNT          911 a          513 c          639 g          870 t
ORIGIN      
        1 tcatatttgg gtataaaaca aaaaatcaat tctaacagtt ttatatcata ataataaata
       61 aaaaagcgat attctagact gtatcaatcc ttttccatta taggagcaac agagtgggag
      121 tagtcatcta aggactaatt tatatatttt tacgagtcag tatcttggga tactggtttt
      181 tactttttta gactttttga ctacttgtta aaactggggt aattttcgac tgtttaatag
      241 ttattataca aagtctaaaa gattagaatt gtcaaaacaa tccgtctagg cttgatttta
      301 tcctttattt actataaaat gagaaggaaa aatgtcaaac ttttatattg caaataggag
      361 aaattatgac aaaaacatta aaacgtcctg aggttttatc acctgcaggg actttagaga
      421 agctaaaggt agctgttcag tatggagcag atgctgtctt tatcggtggt caggcctatg
      481 gtcttcgtag ccgtgcggga aactttactt tcgaacagat ggaagaaggc gtgcagtttg
      541 cggccaagta tggtgccaag gtctatgtag cggctaatat ggttatgcac gaaggaaatg
      601 aagctggtgc tggtgagtgg ttccgtaaac tgcgtgatat cgggattgca gcagttatcg
      661 tatctgaccc agccttgatt atgattgcag cgactgaagc accaggcctt gaaatccacc
      721 tttctaccca agccagtgcc actaactatg aaacccttga gttctggaaa gagctaggct
      781 tgactcgtgt cgttttagcg cgtgaggttt caatggaaga attagctgag atccgcaaac
      841 gtacagatgt tgaaattgaa gcctttgtcc atggagctat gtgtatttca tactctggac
      901 gttgtactct ttcaaaccac atgagtatgc gtgatgccaa ccgtggtgga tgttctcagt
      961 catgccgttg gaaatacgac ctttacgata tgccatttgg gaaagaacgt aagagtttgc
     1021 agggtgagat tccagaagaa ttttcaatgt cagccgttga catgtctatg attgaccaca
     1081 ttccagatat gattgaaaat ggtgtggaca gtctaaaaat cgaaggacgt atgaagtcta
     1141 ttcactacgt atcaacagta accaactgct acaaggcggc tgtggatgcc tatcttgaaa
     1201 gttctgaaaa gtttgaagct atcaaacaag acttagtgga cgagatgtgg aaggttgccc
     1261 aacgtgaatt ggcaacaggt ttctactacg gtataccatc tgaaaatgag cagttgtttg
     1321 gtgctcgccg taaaatccct gagtacaagt ttgtcgctga agtggtttct tatgatgatg
     1381 cggcacaaac agcaaccatt cgtcaacgaa atgtcattaa cgaaggggac caagttgagt
     1441 tttatggtcc aggtttccgt cattttgaaa cctatattga agatttgcat gatgccaaag
     1501 gcaataaaat cgaccgcgct ccaaatccaa tggaactatt gactattaag gtgcctcaac
     1561 ccgttcaatc aggagacatg gttcgtgcat taaaagaagg actcatcaat ctttataagg
     1621 aagatggaac cagcgtcaca gttcgagctt aagaaaggaa aaggaaatga tagaggcaca
     1681 gggtttctta gtggataagc aaacaagatg cattcattac catagcaagc tggatattat
     1741 tgctttacaa tgctatgatt gtaaaaagta ttatgcttgt tatcggtgtc atgattcatt
     1801 agaaaatcac ccttttgagc cgtatccctt atctttgata caggataagc ctattttatg
     1861 tggtgtttgt ctaaaactac taacatataa gcaatataaa gaaagcttaa gttgcctctt
     1921 ttgtttttct cgctttaatc caggttgcca aaatcataag gaacgctatt ttaaatagca
     1981 aatcatctag ttttgaagta ggagaaaact caattccaag agaaaatgaa gtaaatcttc
     2041 ccacaataaa acgcataata tcaagattgt tcaatacctg atactatgcg tttttaagat
     2101 tttaaagact tttttccttt atctggtatt ttgactactt gttaaaactg ggtcaatttt
     2161 caactgttta acagttatta tgcaaagtct aaaagattag aattgtcaaa acaatccgtc
     2221 tagagtatgc gtgatgccaa ccgtggtgga tgttctcagt catgccgttg gaagtacgac
     2281 ctttacgata tgccatttgg gaaagaacgt aagagtttgc agggtgagat tccagaagaa
     2341 ttttcaatgt cagccgttga catgtctatg attgaccaca ttccagatat gattgaaaat
     2401 ggtgtggaca gtctaaaaat cgaaggacgt atggagtcta ttcactatgt attaacagta
     2461 accaactgct acaaggcggc tgtggatgcc tatcttgaaa gtcctgaaaa gtttgaagct
     2521 atcaaacaag acttggtgga cgagatgtgg aaggttgccc aacgtgaact ggctacagga
     2581 ttttactatg gtacaccatc tgaaaatgag cagttgtttg gtgctcgtcg taaaattcct
     2641 gagtacaagt ttgtcgctga agtggtttct tatgatgatg cggcacaaac agcaactatt
     2701 cgtcaacgaa atgtcattaa cgaaggggac caagttgagt tttatggtcc aggtttccgt
     2761 cattttgaaa cctatattga agatttgcat gatgccaaag gcaataaaat cgaccgcgct
     2821 ccaaatccaa tggaactatt gactattaag gtgcctcaac ccgttcaatc aggagacatg
     2881 gttcgtgcat taaaagaagg actcatcaat ctttataagg aagatggaac cag
//
LOCUS       DBEJAU010000097         2890 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC323 isolate 683620
            SAMN38261939-rid24807223.denovo.097, whole genome shotgun sequence.
ACCESSION   DBEJAU010000097 DBEJAU010000000
VERSION     DBEJAU010000097.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261939
            Sequence Read Archive: SRR26833919
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 2890)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2890)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576303.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576303.1
            Genome Coverage       :: 154x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/19/2025 01:05:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,121
            CDSs (total)                      :: 2,078
            Genes (coding)                    :: 1,943
            CDSs (with protein)               :: 1,943
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 36
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 72 of 135
            Pseudo Genes (incomplete)         :: 63 of 135
            Pseudo Genes (internal stop)      :: 51 of 135
            Pseudo Genes (multiple problems)  :: 46 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2890
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261939-rid24807223.denovo.097"
                     /strain="GPSC323"
                     /isolate="683620"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            complement(85..1026)
                     /locus_tag="ACL29Z_002054"
     CDS             complement(85..1026)
                     /locus_tag="ACL29Z_002054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000806289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HGR0070295.1"
                     /translation="MKQTKRIKRWRYYLRRFAYQIKILRVLQSISREKYDEKISASLV
                     YGFLSAVAVNFFFQPGHVYSSGATGLAQIISALSNHWFGFHIPISLSFYAINFPLMVL
                     AWYQIGHKFTVFTFITVSMSSFFIQFVPVATLTEDPIINSLFGGVVMGLGIGFALRNN
                     ISSGGTDIVSLTIRKKTGKNVGSISFLVNGTIMLIAGLTFGWKYALYSMITIFVSSRV
                     TDAVFTKQKRMQAMIVTNHPEKVIEKIHKKLHRGATMIHDAEGTYNHERKAVLITVIT
                     RAEFNEFKQIMTQVDPSSFVSVSENVHILGRFVEIDN"
     gene            complement(1004..2767)
                     /gene="aspS"
                     /locus_tag="ACL29Z_002055"
     CDS             complement(1004..2767)
                     /gene="aspS"
                     /locus_tag="ACL29Z_002055"
                     /EC_number="6.1.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000830881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004812 - aminoacyl-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016874 - ligase activity [Evidence IEA];
                     GO_process: GO:0006418 - tRNA aminoacylation for protein
                     translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate--tRNA ligase"
                     /protein_id="HGR0070296.1"
                     /translation="MKRSMYAGRVREEHIGQEITLKGWVGRRRDLGGLIFIDLRDREG
                     IMQLVINPEKVSAEVMATAESLRSEFVIEVTGQVAAREQANDKLPTGAVELNVTALIV
                     LNTAKTTPFEIKDGIEANDDTRLRYRYLDLRRPEMLENLKLRAKVTHSIRNYLDELEF
                     IDVETPFLSKSTPEGARDYLVPSRVNKGHFYALPQSPQITKQLLMNAGFDRYYQIVKC
                     FRDEDLRGDRQPEFTQVDLETSFLTEQEIQDITEGLIARVMKETKGIEVTLPFPRMKY
                     DDAMALYGSDKPDTRFDMLLQDLTEVVKGVDFKVFSEAPAVKAIVVKGAADNYSRKDI
                     DKMTEVAKQYGAKGLAWVKVVDGELNGPVAKFLTGIQEELTTALALEDKDLVLFVADT
                     LEVANATLGALRGRIAKELGLIDNDKFNFLWVVDWPMFEWSEEEGRYMSAHHPFTLPQ
                     EETAHELEGDLAKVRAIAYDIVLNGYELGGGSLRINQKDLQERMFKALGFSTEEANDQ
                     FGFLLEAMDYGFPPHGGLAIGLDRFVMLLAGEENIREVIAFPKNNKATDPMTQAPSTV
                     ALKQLEELSLQVEEDETNKTN"
BASE COUNT          843 a          674 c          583 g          790 t
ORIGIN      
        1 agatagaact gacgaagtca gtaacatata tacggtaagg cgacgctgac gtggtttgaa
       61 gagattttcg aagagtatta atcactaatt atctatctca acaaatcttc ctagaatatg
      121 aacattttcc gagacagaga caaaggagct tggatccact tgtgtcataa tctgtttaaa
      181 ttcattaaac tctgcacgtg taatgacagt gattaaaact gcctttctct cgtgattata
      241 ggttccttct gcatcgtgga tcatggttgc tccgcggtgc aattttttat ggattttttc
      301 aattaccttc tctggatgat ttgtcacaat catggcctgc atacgctttt gcttagtaaa
      361 gactgcgtct gtcacacggc tagagacaaa gatggtaatc atagaataaa gagcgtattt
      421 ccaaccaaag gtcaaacctg ctatcagcat gatagttcca tttaccaaga aagaaatact
      481 accgacattc ttacccgttt tcttacgaat agtcaggctg acgatatccg tcccaccact
      541 ggagatattg tttcgaagag caaaaccaat ccccaaaccc ataacaacac ccccaaaaag
      601 ggaattgata atgggatcct ccgtcaaggt tgccacaggg acaaactgga taaagaagga
      661 actcatagat accgtgataa aggtaaagac ggtgaactta tggccaatct gataccaagc
      721 taagaccatc aaagggaagt taatggcgta gaagcttagc gaaatcggaa tatgaaaacc
      781 aaaccagtga ttactcaagg cagagataat ctgtgccaga cctgttgcac cactcgaata
      841 cacatgccct ggttggaaaa agaaattaac tgctactgct gataaaaaac catagaccag
      901 agaggccgaa atcttctcat catacttttc tcgagagata ctttgtaaga cacgtaaaat
      961 ttttatctga taagcaaagc ggcgcagata atagcgccac cgcttaattc gttttgtttg
     1021 tttcatcttc ttctacttgt aagctgagtt cctctagttg tttgagagcg actgttgatg
     1081 gagcttgtgt cattgggtca gttgccttgt tgttcttagg aaaggcaatg acttcacgga
     1141 tattttcttc tccagcaagc aacatgacaa aacggtcaag cccgatagcc aaaccaccgt
     1201 gtggtgggaa accatagtcc atggcttcaa gaaggaaacc aaactggtca ttggcttctt
     1261 cagttgagaa accaagagcc ttgaacatgc gttcttgaag gtctttttgg ttgatacgaa
     1321 ggctaccacc accaagctca taaccgttca agacgatatc gtaagcaatg gcacgaacct
     1381 tagccaaatc accttctaat tcgtgagcag tctcttcctg tggaagtgtg aatggatggt
     1441 gggcgctcat gtagcggcct tcttcttcag accattcaaa catcggccag tcaaccaccc
     1501 aaaggaagtt gaacttatca ttatcaatca agccaagctc tttagcaata cgtccacgaa
     1561 gggcacccag tgttgcatta gccacttcaa gcgtatccgc cacaaagaga accaagtcct
     1621 tatcttcaag agcaagcgct gttgtcaatt cttcttggat accagtcaag aacttggcaa
     1681 ctggtccgtt taattctcca tcaaccacct tgacccaagc aagacctttg gcaccatact
     1741 gtttggctac ttccgtcatc ttgtcgatat ctttacgtga atagttgtcc gcagctcctt
     1801 tgaccacaat cgcttttaca gcaggtgctt ctgaaaagac tttaaagtct acacctttga
     1861 ccacttctgt caagtcctga agcaacatgt caaaacgagt atctggcttg tcagaaccgt
     1921 aaagagccat agcatcatcg tatttcatac gagggaacgg tagcgttact tcgatgcctt
     1981 ttgtttcctt catcacgcgc gcgatcaagc cttctgtaat atcttggatt tcttgctcag
     2041 taaggaagga cgtttccaag tcgacctgag taaattcagg ctggcggtct ccacgcaagt
     2101 cttcgtcacg gaaacattta acgatttggt agtaacggtc aaaaccagca ttcatcaaga
     2161 gctgtttcgt gatttgtgga ctttgaggaa gagcgtaaaa atgcccctta ttaacacgag
     2221 acggcactaa ataatcacgc gccccttcag gcgttgactt agaaaggaat ggtgtctcca
     2281 cgtcgataaa ctccaactca tccaagtagt tgcggataga gtgggtcacc ttggcacgaa
     2341 gtttaagatt ttccaacatt tctggacgac gaaggtcaag gtaacggtaa cgcaaacgtg
     2401 tatcgtcatt tgcctcaatg ccatccttaa tctcaaatgg tgttgtctta gctgtgttaa
     2461 gcacaataag agctgtcacg tttaactcaa ccgcaccagt tggcaactta tcattggctt
     2521 gctcacgcgc agcgacctga ccagtcacct caataacaaa ttcgctacga aggctttcag
     2581 ctgttgccat gacctctgca gatacttttt cagggttgat aaccaactgc atgattcctt
     2641 cacggtcacg aagatcgata aagatcaaac caccaaggtc acgacgacgg ccaacccatc
     2701 ctttcaaggt tatttcttgt ccgatgtgtt cctcacgaac acgaccagca tacatactac
     2761 gtttcattat ttctctcctc ttttattctg ttactatttt accataaaag cgcaggctct
     2821 tcatgaaaat catcagaaaa gtttgccagt ctttaaaagt caggtgaaag ccctaaaaat
     2881 tagcgctaat
//
LOCUS       DBEJAU010000098         2687 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC323 isolate 683620
            SAMN38261939-rid24807223.denovo.098, whole genome shotgun sequence.
ACCESSION   DBEJAU010000098 DBEJAU010000000
VERSION     DBEJAU010000098.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261939
            Sequence Read Archive: SRR26833919
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 2687)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2687)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576303.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576303.1
            Genome Coverage       :: 154x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/19/2025 01:05:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,121
            CDSs (total)                      :: 2,078
            Genes (coding)                    :: 1,943
            CDSs (with protein)               :: 1,943
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 36
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 72 of 135
            Pseudo Genes (incomplete)         :: 63 of 135
            Pseudo Genes (internal stop)      :: 51 of 135
            Pseudo Genes (multiple problems)  :: 46 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2687
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261939-rid24807223.denovo.098"
                     /strain="GPSC323"
                     /isolate="683620"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            87..1433
                     /gene="gdhA"
                     /locus_tag="ACL29Z_002056"
     CDS             87..1433
                     /gene="gdhA"
                     /locus_tag="ACL29Z_002056"
                     /EC_number="1.4.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011999806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016639 - oxidoreductase activity, acting
                     on the CH-NH2 group of donors, NAD or NADP as acceptor
                     [Evidence IEA];
                     GO_process: GO:0006520 - amino acid metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-specific glutamate dehydrogenase"
                     /protein_id="HGR0070297.1"
                     /translation="MTSAKEYIQSVFETVKARNGHEAEFLQAVEEFFNTLEPVFEKHP
                     EYIEENILARITEPERVVSFRVPWVDRDGKIQVNRGYRVQFNSAVGPYKGGLRFHPTV
                     NQGILKFLGFEQIFKNVLTGLPIGGGKGGSDFDPKGKTDAEVMRFCQSFMTELQKHIG
                     PSLDVPAGDIGVGGREIGYLYGQYKRLNQFDAGVLTGKPLGFGGSLIRPEATGYGLVY
                     YTEEMLKANGNSFAGKKVVISGSGNVAQYALQKATELGATVISISDSNGYVIDENGID
                     FDLLVDVKEKRRARLTEYAAEKATATYHGGSVWTYAGNYDIALPCATQNEINGEAAKR
                     LVDQGVICVSEGANMPSDLDAITVYKENGIFYGPAKAANAGGVAVSALEMSQNSLRLS
                     WTREEVDGRLKDIMTNIFNTAKTTSETYGLDKDYLAGANIAAFENVANAMIAQGIV"
     gene            complement(1929..2099)
                     /locus_tag="ACL29Z_002057"
     CDS             complement(1929..2099)
                     /locus_tag="ACL29Z_002057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000711941.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0070298.1"
                     /translation="MKKENEYVILTTASLGVMIGIVFAIFLDFPVEYGISLGLLNGIV
                     LGSLIVYKNNKN"
     gene            complement(2112..2681)
                     /locus_tag="ACL29Z_002058"
     CDS             complement(2112..2681)
                     /locus_tag="ACL29Z_002058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001082046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HGR0070299.1"
                     /translation="MPSGLYKIDTGKVLFDGININQIDKKILSQNLGVVPQDSFLLNR
                     SILDNITLKHEVTSQKIEEVCKAVQIYDEIMAMPMKFNTIISEMGSNISGGQRQRIAL
                     ARALINNPSIVILDEATSALDTINEERITKYIKSQGCTQIIVAHRLSTIKDADIIFVM
                     KGGKIVESGNHKYLMDLGGEYYSLYTKRK"
BASE COUNT          831 a          511 c          467 g          878 t
ORIGIN      
        1 gaaaatttct gttttttctt tacagtgaaa aaaaattctg ctataatgtc ttatgtaata
       61 aaatatgaca ataaaaggag aacgatatga catctgctaa agaatatatc caaagcgtgt
      121 ttgaaactgt gaaagctcgt aacgggcacg aggctgaatt cctccaagct gttgaagaat
      181 ttttcaacac tttagaacct gtatttgaaa aacaccctga gtatatcgaa gaaaatatct
      241 tggcacgtat tactgagcct gagcgcgtgg tttctttccg tgttccttgg gttgaccgtg
      301 atggaaaaat tcaagtaaac cgtggttacc gtgttcaatt caactcagct gttggaccat
      361 acaaaggtgg acttcgtttc cacccaactg taaaccaagg gatcttgaaa ttcctcggat
      421 ttgaacaaat ctttaaaaat gtcttgactg gacttcctat cggtggaggt aaaggtggat
      481 cagacttcga tcctaaaggt aaaacagatg ctgaagtgat gcgcttctgc caaagcttca
      541 tgactgaatt gcaaaaacac atcggaccat cacttgacgt acctgctggt gatatcggtg
      601 ttggtggacg tgagattggt tacctttacg gtcaatacaa acgtcttaac caatttgatg
      661 ctggtgtctt gactggtaaa cctcttggat ttggtggtag cttgattcgt ccagaagcaa
      721 ctggttacgg tttggtttac tatactgaag aaatgctcaa agctaacggt aacagctttg
      781 ctggtaagaa agtcgttatt tcaggttcag gtaacgttgc tcaatatgct cttcaaaaag
      841 caactgaact cggtgcaact gttatttcta tttctgactc aaatggttat gtcatcgatg
      901 aaaatggtat cgacttcgat cttttggttg atgttaagga aaaacgtcgt gctcgtttga
      961 ctgagtatgc agctgaaaaa gcaactgcta cttatcatgg aggttctgta tggacttacg
     1021 ctggtaacta tgatatcgct cttccatgtg cgactcaaaa cgaaatcaac ggtgaagcag
     1081 ctaaacgttt ggttgatcaa ggcgttatct gtgtatctga aggtgccaac atgccaagcg
     1141 accttgatgc catcacagtt tacaaagaaa atggtatctt ctacggacct gccaaagctg
     1201 ccaacgctgg tggtgtagcc gtttcagccc ttgaaatgag ccaaaatagt cttcgcctct
     1261 catggactcg tgaagaagtt gatggccgtc tcaaagacat catgacaaac atcttcaaca
     1321 cagctaaaac gacttcagaa acatacggtc ttgataaaga ctaccttgca ggagcaaaca
     1381 ttgctgcctt tgaaaatgta gcaaacgcta tgattgccca aggtattgtt taagatttat
     1441 ttgcttaatc ctcaatcact acgattgggg atttttagtt gagttagaca gttgggaaat
     1501 tctaattaaa tgaaataaaa actgaacaaa ttgattgcgg aattcaaacc aatttctaac
     1561 atatttctag aaattaattt gacttttcta atcgatttgt tcatatctta tttcaattta
     1621 ctatacttac ttaacccttt ttatactcaa tgaaaatcaa agagcaaact aggaagcgag
     1681 ccgcaggctg tacttgagta cggcaaggca aagctgacgt ggtttgaaga gattttcaaa
     1741 gagtattaaa caaaaagaaa aaccgctact cctaagaata gcgatttaat catgttttta
     1801 agctactact gtagttgctc tattatttaa gtgttatgaa taacttcaat atctttaaag
     1861 ctttttgtta gatttataat ttcaactata gccatctcta ctccttagtt tacagcaaaa
     1921 aattatgctt aattcttatt gtttttgtaa acaatcagcg aacccaatac tattccattc
     1981 aacaagccta aagaaatacc atattcaact ggaaaatcta aaaaaattgc aaacactatt
     2041 ccaatcatca cccctagtga ggctgttgtt aaaattacat attcattttc tttcttcatt
     2101 ttctttacac ctcatttcct ttttgtatat aagctgtagt actctccacc aagatccatt
     2161 aagtacttat gatttcctga ctcaacaatc ttaccacctt tcattacaaa aataatatcc
     2221 gcatccttaa tcgttgacaa tctatgagct acaattattt gagtacagcc ctgacttttt
     2281 atatactttg ttattctttc ctcattaata gtgtctaaag cactagttgc ttcatctaaa
     2341 attacaatac taggattatt tattaatgca cgtgccagtg ctatccgttg cctttgccca
     2401 cctgaaatat ttgaccccat ctctgagatg atagtattaa atttcatcgg catagccatg
     2461 atttcatcat agatttgaac tgctttacaa acttcctcta tcttttgtga agtaacttcg
     2521 tgctttaaag ttatattatc aagaatactt cggttcaata aaaatgaatc ctgtggaact
     2581 actcctaaat tttgacttaa tattttttta tctatttgat taatatttat accatcaaat
     2641 aaaacttttc ctgtatcaat cttatataat cctgatggta tttttga
//
LOCUS       DBEJAU010000099         2486 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC323 isolate 683620
            SAMN38261939-rid24807223.denovo.099, whole genome shotgun sequence.
ACCESSION   DBEJAU010000099 DBEJAU010000000
VERSION     DBEJAU010000099.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261939
            Sequence Read Archive: SRR26833919
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 2486)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2486)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576303.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576303.1
            Genome Coverage       :: 154x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/19/2025 01:05:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,121
            CDSs (total)                      :: 2,078
            Genes (coding)                    :: 1,943
            CDSs (with protein)               :: 1,943
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 36
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 72 of 135
            Pseudo Genes (incomplete)         :: 63 of 135
            Pseudo Genes (internal stop)      :: 51 of 135
            Pseudo Genes (multiple problems)  :: 46 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2486
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261939-rid24807223.denovo.099"
                     /strain="GPSC323"
                     /isolate="683620"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            complement(173..838)
                     /locus_tag="ACL29Z_002059"
     CDS             complement(173..838)
                     /locus_tag="ACL29Z_002059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001283913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006813 - potassium ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TrkA family potassium uptake protein"
                     /protein_id="HGR0070300.1"
                     /translation="MSDRTIGILGLGIFGSSVLAALAKQDMNIIAIDDHAERINQFEP
                     VLARGVIGDITDEELLRSAGIDTCDTVVVATGENLESSVLAVMHCKSLGVPTVIAKVK
                     SQTAKKVLEKIGADSVISPEYEMGQSLAQTILFHNSVDVFQLDKNVSIVEMKIPQSWA
                     GQSLSKLDLRGKYNLNILGFREQENSPLDVEFGPDDLLKADTYILAVINNQYLDTLVA
                     LNS"
     gene            complement(852..2231)
                     /locus_tag="ACL29Z_002060"
     CDS             complement(852..2231)
                     /locus_tag="ACL29Z_002060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000897732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015079 - potassium ion transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TrkH family potassium uptake protein"
                     /protein_id="HGR0070301.1"
                     /translation="MLFKLSKEKIELGLSRLSPARRIFLSFALVILLGSLLLSLPFVQ
                     VESSRATYFDHLFTAVSAVCVTGLSTLPVAHTYNIWGQIICLLLIQIGGLGLMTFIGV
                     FYIQSKQKLSLRSRATIQDSFSYGETRSLRKFVYSIFLTTFLVESLGAILLSFRLIPQ
                     LGWGRGLFSSIFLAISAFCNAGFDNLGSTSLFAFQTDLLVNLVIAGLIITGGLGFMVW
                     FDLAGHVGRKKKGRLHFHTKLVLLLTIGLLLFGTATTLFLEWNNAGTIGNLPVADKVL
                     VSFFQTVTMRTAGFSTIDYTQAHPVTLLIYILQMFLGGAPGGTAGGLKITTFFVLLVF
                     ARSELLGLPHANVARRTIAPRTVQKSFSVFIIFLMSFLIGLILLGITAKGNPPFIHLI
                     FETISALSTVGVTANLTPDLGKLALSVIMPLMFMGRIGPLTLFVSLADYHPEKKDMIH
                     YMKADISIG"
BASE COUNT          813 a          567 c          465 g          641 t
ORIGIN      
        1 cccgcagcta gtttcctagt ttgatctttg attttcattg agtattactc tctcttgtca
       61 cttccttcta ttttaccata aagtccagcc tttgaagaac ttttactaga agacaagggg
      121 cttctgtctc tatttgccat cttgggcatc aaaaaagagg ggtcatccct ctttacgaat
      181 tcaatgctac tagggtatcc aaatactggt tgttgatgac tgccaaaata taggtatctg
      241 ctttcaagag gtcatctggt ccaaattcaa catccaatgg ggaattttcc tgctctcgga
      301 aacccaaaat attcagattg tatttgccac ggaggtctaa tttactcaga ctttgacctg
      361 cccaagactg aggaattttc atctccacga tagacacatt tttatccaac tgaaagacat
      421 caacactatt atggaaaaga atggtctgtg ctagagactg tcccatttca tactctggcg
      481 agataaccga gtcagctcca atcttttcta gcactttctt agcggtctga cttttgacct
      541 tagcaataac agtcggtacc cccaaactct tacagtgcat aaccgcaagc acactcgact
      601 ccagattttc acctgtcgcg actacaacgg tatcgcaggt atcaatccct gctgatctca
      661 ataattcttc atctgtgatg tcaccaatca ctccacgcgc caaaactggc tcaaactgat
      721 tgatgcgctc tgcgtggtca tcaatagcga taatattcat atcctgcttg gctagggcag
      781 ctaggacact gctcccaaaa attcccaagc ccaaaattcc aatcgtacga tctgacatgc
      841 tctttccttt cttaaccaat actaatatct gctttcatat agtgaatcat atctttcttt
      901 tctggatggt aatctgccaa gctaacaaac aaggtcaagg gaccaattcg tcccataaac
      961 ataagtggca tgataacact gagagccaat ttcccaaggt caggagtcag atttgccgtt
     1021 acaccaactg tactaagagc tgaaatggtt tcaaatatga ggtggataaa gggaggattg
     1081 cctttggctg ttatccctag cagaatcaat cctatcaaga agctcatcaa aaagataata
     1141 aagacactaa aggatttttg aaccgttcgc ggcgcaatcg ttcgtctcgc aacattggca
     1201 tgaggcaagc ctagaagctc acttcgtgca aagaccaaga ggacaaaaaa tgtcgtaatc
     1261 ttgagtcccc cagctgttcc tccaggtgcc ccacctagaa acatctgtaa gatataaatc
     1321 aaaagagtca caggatgagc ctgagtataa tctatcgtag aaaagccagc tgttcgcatc
     1381 gtcactgttt gaaaaaagct aactaaaacc ttatcggcaa cagggagatt gccaatcgtt
     1441 ccagcattgt tccactcaag aaagagagta gttgccgttc caaataacaa caaacctata
     1501 gtcaacaata gtacaagctt cgtatgaaag tgcagacgtc cttttttctt tcttcctaca
     1561 tgaccagcca aatcaaacca gaccataaaa ccaaggccgc ctgtaataat caagcctgca
     1621 atcaccagat tgaccagtaa atcggtctga aaagcaaata aactggtgct ccctaaatta
     1681 tcaaaaccgg cattacagaa ggctgagatc gctagaaaaa tggaactaaa aagaccacgt
     1741 ccccagccaa gttgaggaat aaggcgaaaa ctaagcaaaa tagctcccaa gctctcaacc
     1801 aaaaaggtcg tgagaaaaat agaatagaca aactttctca aagatcgagt ttctccataa
     1861 ctaaaactat cctgaatagt tgcacggcta cgaagactaa gcttttgctt gctctggata
     1921 tagaaaaccc caataaaggt catgagccct agaccaccga tctgaatcaa gagcaaacag
     1981 attatttggc cccatatatt ataggtgtga gctactggaa gggttgagag acctgtcaca
     2041 cagactgcag agacagcagt gaaaagatga tcaaaataag tcgctcgtga gctttcaact
     2101 tggacaaagg gcaagctcaa aagaagagag cctagtaaaa tgaccaaggc aaaactcaaa
     2161 aaaatacgac gggctggcga taaacgagat aagcctagct ctattttttc cttagataat
     2221 ttgaataaca tgtttccatt gtaccataaa aagctcgaaa tgacttagat aggataaggc
     2281 aaaattcact aacaccaagc ctaaaaaatg ccaccttttt attgatagct taggcaagaa
     2341 caatacttga tagatgtgac tataggtcaa aaaagcaaga caggagcttt taacgccagc
     2401 tactctatat gcttttcagg agaaaatttc tctttttgat tataggcaat gagaaccaag
     2461 gcatcgctta gaaagctagt cacagg
//
LOCUS       DBEJAU010000100         2181 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC323 isolate 683620
            SAMN38261939-rid24807223.denovo.100, whole genome shotgun sequence.
ACCESSION   DBEJAU010000100 DBEJAU010000000
VERSION     DBEJAU010000100.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261939
            Sequence Read Archive: SRR26833919
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 2181)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2181)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576303.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576303.1
            Genome Coverage       :: 154x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/19/2025 01:05:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,121
            CDSs (total)                      :: 2,078
            Genes (coding)                    :: 1,943
            CDSs (with protein)               :: 1,943
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 36
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 72 of 135
            Pseudo Genes (incomplete)         :: 63 of 135
            Pseudo Genes (internal stop)      :: 51 of 135
            Pseudo Genes (multiple problems)  :: 46 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2181
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261939-rid24807223.denovo.100"
                     /strain="GPSC323"
                     /isolate="683620"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            287..961
                     /locus_tag="ACL29Z_002061"
     CDS             287..961
                     /locus_tag="ACL29Z_002061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000934015.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0070302.1"
                     /translation="MKGQKDYVDERLEKRETMIVSNGYAWTRPNHIDTAFASADLFEY
                     KLQLAGQTWGYLEFETNTEKYGKVLLIIKGKKRLTNQFPLVQKNKSGYLFEYAQMNTL
                     YLNQHSSYKNDEDSHSFPIQMELVSDEMIQEIEQATKNSNIEKFMILTYEADSENNII
                     SVDVVMPDARTGQLHLIQDLSEYIQSSSYHFEEAKYQDIPNFSELSETEDFEIIPRIE
                     KQEGQK"
     gene            976..2127
                     /locus_tag="ACL29Z_002062"
     CDS             976..2127
                     /locus_tag="ACL29Z_002062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000481741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HGR0070303.1"
                     /translation="MFNGRVLKELRLLNGLSRAELAQRINLTEQAIWQFESNETKPKL
                     STKMHLANQFHVDLTYFEQEEESIRFDSSVIAFRNADLATRKTIDIQTMYLHKVDSLI
                     DYFESFVIIPNITIHDLSNVVSESYHKGESIEELALYAREKLGISKDNHDLLYKLERS
                     GIYIVERLINDQADAYSAWSKLGRPYIVLGTNKSSVRRNFDLAHELGHILLHKYKDMN
                     EDGDRLEQEANYFASCFLLPKEEFLVKFEERVGKRVSNPDSYILLKSDLNVSIQALEY
                     RAFKLGLLTPKQHSYFYRQIAQKGYKMIEPLDDQIFVKKPSKVKSILDVVLSNHLVSL
                     ATIMSKQSIRLQFISEIFSVEMKFFDQYQEDRRTDRFDNIIPLYKRNNL"
BASE COUNT          796 a          277 c          402 g          706 t
ORIGIN      
        1 agttttatag tgaattgaat ctggaatatt acactacggt tcctaaaata ttttaagaaa
       61 gtgatttgaa tttcccaata aatttgttca gtttttaatt gattttacta tagaagatat
      121 aattttctaa attactctga cacagaactt taagaaaaag ctaattattg tagtaatttc
      181 tttaagaaaa tgatataatt cattaaaaag tatttggagg aggaagaatt atgttgaatc
      241 agatctcttt gattcgcttg aggcacaaaa aattgtagat actttgatga aagggcaaaa
      301 agattatgta gatgaacgtc tagaaaaaag agagacaatg atagtgtcga atggttatgc
      361 atggacgcga cctaatcata ttgatactgc atttgcatca gcagatttgt ttgagtataa
      421 attacaatta gcaggacaga cttggggata tttagaattt gaaacaaaca cagaaaaata
      481 tgggaaagta ttgttaatta taaagggtaa gaagcgactt acgaaccaat ttcctttggt
      541 acaaaaaaat aagagtggct acttatttga atatgctcag atgaatacac tttatcttaa
      601 tcaacattct tcctacaaaa atgatgaaga tagtcattcc tttccaattc agatggagtt
      661 agtttctgat gaaatgattc aagaaattga acaagctact aaaaattcga atatcgaaaa
      721 atttatgatt ttaacttatg aggcggactc agaaaacaat attatatctg tagatgttgt
      781 tatgcctgat gcacgaactg gtcagttaca cttgattcaa gatttgtctg agtatattca
      841 atcaagttcg taccatttcg aagaagctaa atatcaagat attcctaatt tttcagaatt
      901 atcggaaaca gaagattttg aaattattcc aagaatagaa aaacaagaag gtcaaaagta
      961 gtaaggagta tgtaaatgtt taatggtcgg gtattgaaag aattacggct gttaaatggt
     1021 ttaagtagag cagaattagc tcagagaatt aatttaacgg aacaagccat ttggcagttt
     1081 gagtccaacg aaacgaaacc taaattatca accaaaatgc atttggccaa ccaatttcat
     1141 gttgatttaa cttattttga acaggaagaa gagagcattc gatttgattc ttctgtaatt
     1201 gcctttagaa atgcagacct agcaacacgg aaaacaatag atattcaaac tatgtattta
     1261 cataaggtag atagtttgat tgattatttt gaaagttttg taattatacc taatattaca
     1321 attcatgacc taagtaatgt agtgagtgaa tcttatcata agggagaatc cattgaggaa
     1381 ttggctcttt atgccaggga aaaattaggt atttcaaaag ataatcatga tttgctttat
     1441 aaattagaac gttcaggcat ctatatcgtg gaacgattaa ttaatgacca agctgatgct
     1501 tatagcgcat ggtcaaaatt gggaagacct tatattgtgt tgggaacgaa taaatcatct
     1561 gtacgtcgaa attttgactt agctcatgag ctaggacata ttcttttaca taaatataaa
     1621 gatatgaatg aagatggcga tcgtttggag caagaagcaa attattttgc atcatgtttt
     1681 ttattgccaa aagaagagtt tttagtcaaa tttgaagaga gggttggcaa gcgtgtcagc
     1741 aatcctgata gttatatttt attgaagtcg gatttgaatg tttcgataca ggctttagag
     1801 tatcgagctt ttaagttagg attattgact ccaaagcaac attcttactt ttatcgtcaa
     1861 attgcgcaaa aaggttacaa aatgattgaa cctttggatg atcaaatttt tgttaaaaaa
     1921 ccaagcaaag taaagagtat tctggacgtc gttttgagta atcatctagt cagtctagcg
     1981 actataatgt ctaaacaaag tattcgttta cagtttataa gcgaaatatt ttcagtcgaa
     2041 atgaaatttt ttgatcagta tcaagaagat agaagaacag atcgatttga taacatcatc
     2101 cctttgtaca aaagaaataa tttataattt aactgtgaaa taatttcatg aaggacatat
     2161 ggcagaaatt ggactttatc a
//
LOCUS       DBEJAU010000101         2132 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC323 isolate 683620
            SAMN38261939-rid24807223.denovo.101, whole genome shotgun sequence.
ACCESSION   DBEJAU010000101 DBEJAU010000000
VERSION     DBEJAU010000101.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261939
            Sequence Read Archive: SRR26833919
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 2132)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2132)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576303.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576303.1
            Genome Coverage       :: 154x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/19/2025 01:05:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,121
            CDSs (total)                      :: 2,078
            Genes (coding)                    :: 1,943
            CDSs (with protein)               :: 1,943
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 36
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 72 of 135
            Pseudo Genes (incomplete)         :: 63 of 135
            Pseudo Genes (internal stop)      :: 51 of 135
            Pseudo Genes (multiple problems)  :: 46 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2132
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261939-rid24807223.denovo.101"
                     /strain="GPSC323"
                     /isolate="683620"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            70..608
                     /locus_tag="ACL29Z_002063"
                     /pseudo
     CDS             70..608
                     /locus_tag="ACL29Z_002063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399595.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
     gene            675..1085
                     /locus_tag="ACL29Z_002064"
     CDS             675..1085
                     /locus_tag="ACL29Z_002064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262849.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl transferase family 2"
                     /protein_id="HGR0070304.1"
                     /translation="MYYLPVDFYRYLIGREDQSVNEQVMIKCIDQQLKVNRLLVDQLD
                     LSQVSHPKMREYLLNHIEITTVISSTLLNRSETAEHLAKKRQLWTYIQQKNPEVFQAI
                     RKTMLSRLTKHSVLPDRKLSNVVYQITKSVYGFN"
     gene            1201..>2132
                     /gene="pavB"
                     /locus_tag="ACL29Z_002065"
     CDS             1201..>2132
                     /gene="pavB"
                     /locus_tag="ACL29Z_002065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000671444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fibronectin-binding SSURE repeat adhesin PavB"
                     /protein_id="HGR0070305.1"
                     /translation="MKFNPNQRYTRWSIRRLSVGVASVVVASGFFVLVGQPSSVRADV
                     VNPTPGQVLPEETSGTKEGDLSEKPGDTVLTQAKPEGVTGNTNSLPTPTERTEVSEET
                     NSSSLDTLFEKDEEAQKNPELTDVLKETVDTADVDGTQASLAETTPEQVKGGVKENTK
                     DSIDVPAAYLEKAEGKGPFTAGVNQVIPYELFAGDGMLTRLLLKASDNAPWSDNGTAK
                     NPALPPLEGLTKGKYFYEVDLNGNTVGKQGQALIDQLRANGTQTYKATVKVYGNKDGK
                     ADLTNLVATKNVDININGLVAKETVEKAVKDNVK"
BASE COUNT          655 a          403 c          473 g          601 t
ORIGIN      
        1 gacgttgacg cggtttgaag agattttcga agagtataag aaaaaatcag ttccctaaag
       61 gagcagatta tgaagttatt gtctatcgct atttctagct ataatgcagc agcctatctt
      121 cattactgtg tggagtcgct agtgattggt ggtgagcaag ttgggatttt gattatcaat
      181 gacgggtctc aggaccagac tcaggaaatc gctgagtgtt tagctagcaa gtatcctaat
      241 atcgttagag ccatctatca ggaaaataaa ggacatggcg gtgtggtcaa tcgcggcttg
      301 gcagaggctt ctgggcgcta ttttaaagta gttgacagtg atgactggtg gatcctcgtg
      361 cctacttgaa aattcttgaa accttgcagg aacttgagag caagggtcaa gagatggatg
      421 tctttgtgac caattttgtc tatgaaaagg aaggtcagtc tcgtaagaag agtatgagtt
      481 acgagtcagt cttgcctgtt cggcagattt ttggctggga ccaggtcgga aatttctcca
      541 aaggccagta tatcatgatg cactcgctga tttatcggac agctttgttg cgtgctagcc
      601 agttctaact gcctgaacat actttttatg tcgataatct ctttgtcttt acgccccttc
      661 agcaggtcaa gaccatgtac tatctgcctg tcgatttcta tcgttatttg attgggcgtg
      721 aggaccagtc tgtcaatgag caagtgatga ttaagtgcat tgaccagcaa ctcaaggtca
      781 atcgactctt ggtagaccag cttgatttgt cccaagtgag tcatcccaaa atgcgagaat
      841 atctgctgaa tcatattgaa atcacgacgg tgatttccag taccctgctc aaccgatctg
      901 aaacagcgga gcatctggca aaaaaacgcc aattgtggac ctatattcag cagaaaaatc
      961 cagaagtctt tcaggctatt cgtaagacca tgttgagccg tttgaccaaa cattctgtct
     1021 tgccagatcg caaactgtcc aatgtcgtct atcaaatcac caaatctgtt tatggattta
     1081 attaatataa gtgttttata agagggattt aagaaaaatt ttaacttttt cttagtcctt
     1141 tttaatttca ggagattata ctagagtcat caaataaaga aagactctaa ggagaatcct
     1201 atgaaattca atccaaatca aagatatact cgttggtcta ttcgccgtct cagtgtcggt
     1261 gttgcctcag ttgttgtggc tagtggcttc tttgtcctag ttggtcagcc aagttctgta
     1321 cgtgccgatg tggtcaatcc gaccccaggt caagtcttac ctgaagagac atcgggaacg
     1381 aaagagggtg acttatcaga aaaaccagga gacaccgttc tcactcaagc gaaacctgag
     1441 ggcgttactg gaaatacgaa ttcacttccg acacctacag aaagaactga agtgagcgag
     1501 gaaacaaact cttctagtct ggatacactt tttgaaaaag atgaagaagc tcaaaaaaat
     1561 ccagagctaa cagatgtctt aaaagaaact gtagatacag ctgatgtgga tgggacacaa
     1621 gcaagtctag cagaaactac tcctgaacaa gtaaaaggtg gagtgaaaga aaatacaaaa
     1681 gacagcatcg atgttcctgc tgcttatctt gaaaaagctg aagggaaagg tcctttcact
     1741 gccggtgtaa accaagtaat tccttatgaa ctattcgctg gtgatggtat gttaactcgt
     1801 ctattactaa aagcttcgga taatgctcct tggtctgaca atggtactgc taaaaatcct
     1861 gctttacctc ctcttgaagg attaacaaaa gggaaatact tctatgaagt agacttaaat
     1921 ggcaatactg ttggtaaaca aggtcaagct ttaattgatc aacttcgcgc taatggtact
     1981 caaacttata aagctactgt taaagtttac ggaaataaag acggtaaagc tgacttgact
     2041 aatctagttg ctactaaaaa tgtagacatc aacatcaatg gattagttgc taaagaaact
     2101 gtcgaaaaag ctgttaaaga taacgttaaa ga
//
LOCUS       DBEJAU010000102         2118 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC323 isolate 683620
            SAMN38261939-rid24807223.denovo.102, whole genome shotgun sequence.
ACCESSION   DBEJAU010000102 DBEJAU010000000
VERSION     DBEJAU010000102.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261939
            Sequence Read Archive: SRR26833919
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 2118)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2118)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576303.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576303.1
            Genome Coverage       :: 154x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/19/2025 01:05:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,121
            CDSs (total)                      :: 2,078
            Genes (coding)                    :: 1,943
            CDSs (with protein)               :: 1,943
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 36
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 72 of 135
            Pseudo Genes (incomplete)         :: 63 of 135
            Pseudo Genes (internal stop)      :: 51 of 135
            Pseudo Genes (multiple problems)  :: 46 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2118
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261939-rid24807223.denovo.102"
                     /strain="GPSC323"
                     /isolate="683620"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            2..1594
                     /locus_tag="ACL29Z_002066"
     CDS             2..1594
                     /locus_tag="ACL29Z_002066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000288036.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HGR0070306.1"
                     /translation="MKKFSLLTIFIVAGQLLLIYAATINALVLNELIAMNLERFLKLS
                     IYQMIVWCGIIFLDWVVKNYQVEVIQEFNLEIRNRVATDISNSTYQEFHSKSSGTYLS
                     WLNNDVQTLNDQAFKQLFLVIKGISGTIFAVVTLNHYHWSLTVATLFSLMIMLLVPKI
                     FASKMREVSLNLTNQNEAFLKSSETILNGFDVLASLNLLYVLPKKIKEAGILLKMVIQ
                     RKTTVETLAGAISFFLNIFFQISLVFLTGYLAIKGIVKIGTIEAIGALTGVIFTALGE
                     LGGQLSSIIGTKPIFLKLYSINPIESNKMNDIEPNEVNRDFPLYEAKNICYKYGDKEI
                     LKNLNFCFQRNEKYLILGESGSGKSTLLKLLNGFLRDYSGELRFCGDDIKKTSYLNMV
                     SNVLYVDQKAYLFEGTIRDNILLEENYTDEEILQSLEQVGLSVKDFPNNILDYYVGDD
                     GRLLSGGQKQKITLARGLIRNKKIVLIDEGTSAIDRRTSLAIERKILDREDLTVIIVT
                     HAPHPELKQYFTKIYQFPKDFI"
     gene            1855..>2118
                     /locus_tag="ACL29Z_002067"
     CDS             1855..>2118
                     /locus_tag="ACL29Z_002067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000555526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0070307.1"
                     /translation="MSEIVEMSKKISDLNDKKEFHKKNCELRFQDSVLDNINSVPGTT
                     HLFSCLNIQTLVKIILYIFRYNSCMKIFNFRDKELIFFNKIVNG"
BASE COUNT          745 a          250 c          382 g          741 t
ORIGIN      
        1 tataaaaaaa tttagtttat taacgatatt tattgttgct ggtcaattat tgctaattta
       61 tgcagcaact attaatgctc tggtgttgaa tgaattaatt gcgatgaatt tagagcggtt
      121 tttgaaattg tcaatctacc aaatgattgt ctggtgtggg ataatattcc ttgactgggt
      181 agtgaaaaat tatcaggttg aagtgatcca agagtttaat ctagagattc gaaatagagt
      241 tgccacagac atctctaact ctacctatca agaatttcat agtaaatcat caggaacata
      301 tctttcgtgg ctaaataatg atgttcagac tttaaatgat caggctttta aacaactttt
      361 tttagtaata aaaggaattt ctggtactat atttgcagtt gtgactctta atcactatca
      421 ttggtcattg actgtagcca ccttgttttc attaatgatt atgctacttg taccaaaaat
      481 ctttgcatcg aaaatgcgag aagttagtct aaatttaact aaccaaaatg aagctttttt
      541 aaaatctagt gagactatat tgaatggatt tgatgtgtta gcgtccttga atcttttata
      601 tgtattgcct aagaaaatta aagaagcagg aattttatta aagatggtta tacaaagaaa
      661 gacaactgta gaaacgttag caggcgctat tagcttcttt ctcaatattt tttttcagat
      721 atctctcgtt tttttaacag gctatcttgc aataaaagga atagtgaaaa ttggtactat
      781 tgaagcaata ggagcactaa caggtgttat ttttacagcg ctaggtgaat taggaggtca
      841 attatcctct attattggta cgaagcctat ttttttaaaa ttgtattcaa ttaatccaat
      901 tgagtcaaat aaaatgaatg atatcgaacc aaatgaggtg aatagagatt ttccgttata
      961 tgaagcaaaa aatatttgct ataagtatgg agataaagaa atattaaaaa acttaaattt
     1021 ttgttttcaa cgtaatgaaa agtatttaat tttaggtgaa agtggaagcg ggaaatctac
     1081 attattaaaa ttattgaatg gctttttgag agattatagt ggagaattgc gattctgcgg
     1141 ggatgatata aaaaaaacct cctatttaaa tatggtttcg aatgttctat atgtagatca
     1201 aaaagcttat ttgtttgaag gtacgattag agataatatt ttattggaag aaaattatac
     1261 tgatgaagaa atactacagt ctttagagca agttggtttg agtgtaaaag attttcctaa
     1321 taacatttta gattattatg ttggtgatga tgggagatta ctgtcaggag ggcagaaaca
     1381 aaaaattact ttagctagag ggctaattag aaataagaaa atagtattaa ttgacgaggg
     1441 aacttctgct atcgatagga gaacttcgtt agcgattgaa cgtaagatat tagatagaga
     1501 ggatttgact gtcattattg ttacccatgc tccgcatccg gaacttaaac aatattttac
     1561 taagatatat caatttccaa aggattttat ttaagaatat aggggaggga aacatgagat
     1621 tctattgtga agcttatgag gtaattactg aagagaaaaa agtatcattt ttttatgtag
     1681 atgagaaacc cttaaggtat ctgttatttg actatatatt tctactagtt ctagctaaaa
     1741 aaaaatatcc caatcttatg aactgcaccc caaaagttag atttattctg tctaactttt
     1801 ggggtgcagt tcattttgca tagttttggc attcatccta gatatccata taaaatgtct
     1861 gagattgttg aaatgtctaa aaaaatatca gatctaaacg ataaaaaaga atttcacaaa
     1921 aagaactgtg agttgaggtt tcaagatagt gttcttgata acataaatag tgtcccgggt
     1981 acaactcatt tatttagttg tttaaatatt caaacattag taaaaattat tttatatatt
     2041 tttcgataca acagttgtat gaaaatattt aattttagag ataaagagct tatctttttt
     2101 aataagattg taaatggg
//
LOCUS       DBEJAU010000103         1875 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC323 isolate 683620
            SAMN38261939-rid24807223.denovo.103, whole genome shotgun sequence.
ACCESSION   DBEJAU010000103 DBEJAU010000000
VERSION     DBEJAU010000103.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261939
            Sequence Read Archive: SRR26833919
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 1875)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1875)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576303.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576303.1
            Genome Coverage       :: 154x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/19/2025 01:05:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,121
            CDSs (total)                      :: 2,078
            Genes (coding)                    :: 1,943
            CDSs (with protein)               :: 1,943
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 36
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 72 of 135
            Pseudo Genes (incomplete)         :: 63 of 135
            Pseudo Genes (internal stop)      :: 51 of 135
            Pseudo Genes (multiple problems)  :: 46 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1875
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261939-rid24807223.denovo.103"
                     /strain="GPSC323"
                     /isolate="683620"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            <1..246
                     /locus_tag="ACL29Z_002068"
     CDS             <1..246
                     /locus_tag="ACL29Z_002068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000904570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA damage-inducible protein P"
                     /protein_id="HGR0070308.1"
                     /translation="KKELTLLSEKVALNLHQQEKAGKIVILKIRYEDFSTLTKRKSLA
                     QKTQDASQISQIALQLYEELSKKERGVRLLGITMTGF"
     gene            complement(393..1238)
                     /locus_tag="ACL29Z_002069"
     CDS             complement(393..1238)
                     /locus_tag="ACL29Z_002069"
                     /EC_number="3.6.1.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000273482.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0050380 - undecaprenyl-diphosphatase
                     activity [Evidence IEA];
                     GO_process: GO:0016311 - dephosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="undecaprenyl-diphosphate phosphatase"
                     /protein_id="HGR0070309.1"
                     /translation="MYLIEILKSIFFGIVEGITEWLPISSTGHLILAEEFIQYQNQNE
                     AFMSMFNVVIQLGAILAVMVIYFNKLNPFKPTKDKQEVRKTWRLWLKVLIATLPLLGV
                     FKFDDWFDTHFHNMVSVALMLIIYGVAFIYLEKRNKARAIEPSVTELDKLPYTTAFYI
                     GLFQVLALLPGTSRSGATIVGGLLNGTSRSVVTEFTFYLGIPVMFGASALKIFKFVKA
                     GELLSFGQLFLLLVAMGVAFAVSMVAIRFLTSYVKKHDFTLFGKYRIVLGSVLLLYSF
                     VRLFV"
     gene            1493..>1875
                     /locus_tag="ACL29Z_002070"
     CDS             1493..>1875
                     /locus_tag="ACL29Z_002070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001841243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HGR0070310.1"
                     /translation="MLYVGIDIAKNKHDVTALNVPGKTVLKPLTFSNNKAGFELLDLS
                     IRQINQDCLIALEDTGHYAFNLLNFLHEQGYKVYTYNPLLIKEFAKSLSLRKTKTDKK
                     DAHGIALKLLSDPNREQFQHDNRQV"
BASE COUNT          651 a          396 c          338 g          490 t
ORIGIN      
        1 aaaaaagagc tgactcttct atcagaaaaa gtcgctctca atctacatca acaagaaaaa
       61 gctggaaaaa ttgtcatttt gaaaatccgc tacgaggact tttcaactct taccaaacga
      121 aaaagtcttg ctcaaaaaac acaagatgct agtcagataa gccaaatagc cctgcaactc
      181 tatgaagaat taagcaagaa agaaagaggt gtccgcctat tggggattac catgactgga
      241 ttttaaagct caatgaaaat caaagagcaa actaggaggc tagccgcagg ctgctcaaaa
      301 cactgttttg aggttgcaga taaagctgac gcggtttgaa gagattttcg aagagtataa
      361 aaccttgaag agttgcccct tcaaggtttt tcttatacaa ataaacggac aaaactgtaa
      421 agtagcaaaa cactaccaag cacgatacgg tatttaccaa aaagggtgaa gtcgtgtttt
      481 ttcacatagc tggtcaagaa gcgaatagcc accatgctga ccgcaaaagc tactcccatc
      541 gcgaccaaga gcaaaaacaa ttgcccaaag ctcaagagtt ctccggcttt cacaaatttg
      601 aaaatcttta aggcactagc tccaaacata acaggaatcc caagatagaa ggtaaattct
      661 gtcacaactg aacgactggt tccatttaac aaaccaccga caatcgttgc acctgaacgg
      721 ctagtccctg gtaaaagagc aagaacttgg aagagtccga tatagaaagc ggtcgtataa
      781 ggaagcttgt ccaactctgt tacacttggc tcgatagcac gcgctttatt gcgcttttcc
      841 aaatagatga aggcaacccc gtagataatc aacatgagag caactgaaac catgttatgg
      901 aagtgggtat caaaccaatc atcaaattta aagacaccaa gtaaaggtaa agtagcaatc
      961 aagaccttca accatagtct ccaagtctta cgaacttcct gtttgtcctt ggtcggttta
     1021 aaaggattga gcttgttaaa ataaatcacc ataactgcta aaatagcacc aagctgaatc
     1081 acgacattaa acatggacat aaaggcttca ttttgatttt ggtattggat gaattcctct
     1141 gctaaaatca agtgacctgt actggaaatc ggcaaccatt ccgtaattcc ttcaacaatt
     1201 ccgaagaaga tagattttaa aatttcaata agatacatag attactccct atattatatt
     1261 tagcgcagtt agctactgcc aaagcccaag tggtatactt ggaataagcc actatggatt
     1321 agttcatttc ctccaatcgc ttgacgattt ccgaaaggct ctaaccacag cttttgtttc
     1381 aattggtaat gagtttgata acgcatagac gtttgatctc gtctaaggta acaaggcaaa
     1441 aaattcgtgg ataaccaagt agacttgaaa tactatatct ggagatactc ccatgcttta
     1501 tgtaggcatt gatatcgcta aaaataaaca cgatgttaca gccttgaatg ttccaggaaa
     1561 aactgttctt aaaccactca ctttttcaaa taataaagct ggttttgaac tcttagatct
     1621 gtctattcga cagatcaacc aagactgtct catcgctctt gaagatactg gacattatgc
     1681 ctttaatcta ctgaacttcc tgcatgaaca aggatataaa gtttacacct acaatccttt
     1741 gctcatcaag gaatttgcca aatcattatc acttcgcaag actaaaacgg ataagaaaga
     1801 cgctcatggc atcgctctta aacttctttc tgaccccaat cgtgaacaat ttcaacacga
     1861 taatcggcaa gtaga
//
LOCUS       DBEJAU010000104         1691 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC323 isolate 683620
            SAMN38261939-rid24807223.denovo.104, whole genome shotgun sequence.
ACCESSION   DBEJAU010000104 DBEJAU010000000
VERSION     DBEJAU010000104.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261939
            Sequence Read Archive: SRR26833919
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 1691)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1691)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576303.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576303.1
            Genome Coverage       :: 154x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/19/2025 01:05:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,121
            CDSs (total)                      :: 2,078
            Genes (coding)                    :: 1,943
            CDSs (with protein)               :: 1,943
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 36
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 72 of 135
            Pseudo Genes (incomplete)         :: 63 of 135
            Pseudo Genes (internal stop)      :: 51 of 135
            Pseudo Genes (multiple problems)  :: 46 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1691
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261939-rid24807223.denovo.104"
                     /strain="GPSC323"
                     /isolate="683620"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            18..1019
                     /locus_tag="ACL29Z_002071"
     CDS             18..1019
                     /locus_tag="ACL29Z_002071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000789954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HGR0070311.1"
                     /translation="MKNINGKKVTIYDIARLSGFSPKTVSRVINGGVNVKEETYQAIQ
                     KVIEELSYIPNAYAKNLTKKEAINILISVKKIDSFPLIWFHTLLDKVLRTCKEFGVNA
                     IVEYFGEEDTISNSIISSTGSLVDGVIVFYESVDDIRIQYLKKNHMPFLVFGESQTSG
                     VVYVSNNNFQATYDMMKAVTEEKFKNMWLLMGGESHVNKDRERGVRSFLNDKNYFMDL
                     KVIYGLSTIDSVYSYAMQHLTTQNYPDIIFVSGDEKVQGLIRACYEKGILIPDDISII
                     GFDNIPISQYYTPALSTIAPNYVKLAKEMIEGVLAIIKGESVTSVEVSPKFVRRQSF"
     misc_binding    1231..1460
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
BASE COUNT          561 a          228 c          344 g          558 t
ORIGIN      
        1 cgtaatggag gactgaaatg aaaaatataa atgggaaaaa ggtaactatt tatgatattg
       61 cacgtttatc aggtttttct ccaaaaacag tttcacgagt tattaatggt ggagtaaatg
      121 ttaaagaaga aacttatcaa gcgattcaaa aagttataga ggaattgtcg tatattccaa
      181 atgcgtatgc aaaaaattta actaaaaaag aagctataaa tatattgatt tctgtaaaaa
      241 aaatcgactc ttttccttta atttggtttc atacgctgtt agataaagtg ttacggacgt
      301 gtaaagaatt tggtgttaat gctatagttg agtactttgg agaggaggat acaattagta
      361 attcgattat atcaagcaca ggtagcctag tagatggtgt tattgttttt tatgaaagtg
      421 tagatgatat cagaattcag tatttaaaga agaaccatat gccttttctt gttttcggtg
      481 aatctcaaac gtctggagta gtctatgtat ctaataataa ttttcaagct acttatgata
      541 tgatgaaagc tgtaactgaa gaaaaattta aaaatatgtg gttgcttatg ggaggagaat
      601 ctcatgttaa taaggatcgt gaaagaggtg tgcgttcttt tctgaatgat aaaaattact
      661 ttatggattt aaaagtcatt tatggcttat ctacaattga ttcagtttat tcttatgcaa
      721 tgcagcactt gactacccaa aattatccgg acattatttt tgtttcagga gatgaaaagg
      781 ttcagggctt gattcgtgcg tgctatgaga aaggaattct tattccagat gatatttcta
      841 tcattggatt tgataatatt cctatttctc agtattatac tccagctttg tctacaattg
      901 ctcccaatta tgttaaattg gctaaagaaa tgatagaagg tgttttagca attattaaag
      961 gggaaagtgt cacatctgtt gaagtttctc ctaaatttgt taggagacag agtttctagt
     1021 attgtttaat tcttgaaaat cctagtggaa aagatggagt gttctaaaat aagttctgtt
     1081 tagcctccat tcagtttcta ttgagttgga tccaatttct aagaagtggg acatgttcat
     1141 gttcgatcta aggaagacat ggtcacattc gaatgatatt ttcaaaaaaa tcgtaaaaaa
     1201 gtcttgacaa agaaaaaaca aagtattaaa ataagttcaa caaatcagaa aagtaactat
     1261 ttttgatctt cagggagcct gtggtggttg tgaataggtg gttggaagta gtgaaagtgg
     1321 gctgattttg aaaatgaatt tgaaacaatg aaaattcggt gcgcacacct tacagtgcag
     1381 cttgttgtta aacaaggcag agatgtaaag ggatagtccc tttataattg aggtggcacc
     1441 gcgttaccaa cgccctcaca cggaagtata ttctgtgtgt gggctttttt ctatccgtcg
     1501 tttggtttat cttttattag ggccttaagt cgctttgatg aacttgagtt ctatctacag
     1561 ctccttgcct actactaaaa gcaaacaaaa aggctggact aatacgaaaa aagctagtaa
     1621 tactcaatga aaatcaaaga gcaaactagg aaactagccg caggctgctc aaaacactgt
     1681 tttgaggttg t
//
LOCUS       DBEJAU010000105         1669 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC323 isolate 683620
            SAMN38261939-rid24807223.denovo.105, whole genome shotgun sequence.
ACCESSION   DBEJAU010000105 DBEJAU010000000
VERSION     DBEJAU010000105.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261939
            Sequence Read Archive: SRR26833919
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 1669)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1669)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576303.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576303.1
            Genome Coverage       :: 154x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/19/2025 01:05:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,121
            CDSs (total)                      :: 2,078
            Genes (coding)                    :: 1,943
            CDSs (with protein)               :: 1,943
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 36
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 72 of 135
            Pseudo Genes (incomplete)         :: 63 of 135
            Pseudo Genes (internal stop)      :: 51 of 135
            Pseudo Genes (multiple problems)  :: 46 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1669
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261939-rid24807223.denovo.105"
                     /strain="GPSC323"
                     /isolate="683620"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            <1..>1669
                     /gene="phtD"
                     /locus_tag="ACL29Z_002072"
     CDS             <1..>1669
                     /gene="phtD"
                     /locus_tag="ACL29Z_002072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000700388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal histidine triad protein PhtD"
                     /protein_id="HGR0070312.1"
                     /translation="YLKDAAHADNIRTKEEIKRQKQERSHNHNSRADNAVAAARAQGR
                     YTTDDGYIFNASDIIEDTGDAYIVPHGDHYHYIPKNELSASELAAAEAYWNGKQGSRP
                     SSSSSYNANPAQPRLSENHNLTVTPTYHQNQGENISSLLRELYAKPLSERHVESDGLI
                     FDPAQITSRTARGVAVPHGNHYHFIPYEQMSELEKRIARIIPLRYRSNHWVPDSRPEQ
                     PSPQPTPEPSPSPQPAPNPQPAPSNPIDEKLVKEAVRKVGDGYVFEENGVSRYIPAKD
                     LSAETAAGIDSKLAKQESLSHKLGAKKTDLPSSDREFYNKAYDLLARIHQDLLDNKGR
                     QVDFEALDNLLERLKDVSSDKVKLVDDILAFLAPIRHPERLGKPNAQITYTDDEIQVA
                     KLAGKYTTEDGYIFDPRDITSDEGDAYVTPHMTHSHWIKKDSLSEAERAAAQAYAKEK
                     GLTPPSTDHQDSGNTEAKGAEAIYNRVKAAKKVPLDRMPYNLQYTVEVKNGSLIIPHY
                     DHYHNIKFEWFDEGLYEAPKGYSLEDLLATVKYYVEHPNERPHSDNGF"
BASE COUNT          533 a          361 c          352 g          423 t
ORIGIN      
        1 taccttaagg atgcagctca tgcggataat attcggacaa aagaagagat taaacgtcag
       61 aagcaggaac gcagtcataa tcataactca agagcagata atgctgttgc tgcagccaga
      121 gcccaaggac gttatacaac ggatgatggg tatatcttca atgcatctga tatcattgag
      181 gacacgggtg atgcttatat cgttcctcac ggcgaccatt accattacat tcctaagaat
      241 gagttatcag ctagcgagtt agctgctgca gaagcctatt ggaatgggaa gcagggatct
      301 cgtccttctt caagttctag ttataatgca aatccagctc aaccaagatt gtcagagaac
      361 cacaatctga ctgtcactcc aacttatcat caaaatcaag gggaaaacat ttcaagcctt
      421 ttacgtgaat tgtatgctaa acccttatca gaacgccatg tagaatctga tggccttatt
      481 ttcgacccag cgcaaatcac aagtcgaacc gccagaggtg tagctgtccc tcatggtaac
      541 cattaccact ttatccctta tgaacaaatg tctgaattgg aaaaacgaat tgctcgtatt
      601 attccccttc gttatcgttc aaaccattgg gtaccagatt caagaccaga acaaccaagt
      661 ccacaaccga ctccggaacc tagtccaagt ccgcaacctg caccaaatcc tcaaccagct
      721 ccaagcaatc caattgatga gaaattggtc aaagaagctg ttcgaaaagt aggcgatggt
      781 tatgtctttg aggagaatgg agtttctcgt tatatcccag ccaaggatct ttcagcagaa
      841 acagcagcag gcattgatag caaactggcc aagcaggaaa gtttatctca taagctagga
      901 gctaagaaaa ctgacctccc atctagtgat cgagaatttt acaataaggc ttatgactta
      961 ctagcaagaa ttcaccaaga tttacttgat aataaaggtc gacaagttga ttttgaggct
     1021 ttggataacc tgttggaacg actcaaggat gtctcaagtg ataaagtcaa gttagtggat
     1081 gatattcttg ccttcttagc tccgattcgt catccagaac gtttaggaaa accaaatgcg
     1141 caaattacct acactgatga tgagattcaa gtagccaagt tggcaggcaa gtacacaaca
     1201 gaagacggtt atatctttga tcctcgtgat ataaccagtg atgaggggga tgcctatgta
     1261 actccacata tgacccatag ccactggatt aaaaaagata gtttgtctga agctgagaga
     1321 gcggcagccc aggcttatgc taaagagaaa ggtttgaccc ctccttcgac agaccatcag
     1381 gattcaggaa atactgaggc aaaaggagca gaagctatct acaaccgcgt gaaagcagct
     1441 aagaaggtgc cacttgatcg tatgccttac aatcttcaat atactgtaga agtcaaaaac
     1501 ggtagtttaa tcatacctca ttatgaccat taccataaca tcaaatttga gtggtttgac
     1561 gaaggccttt atgaggcacc taaggggtat agtcttgagg atcttttggc gactgtcaag
     1621 tactatgtcg aacatccaaa cgaacgtccg cattcagata atggttttg
//
LOCUS       DBEJAU010000106         1482 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC323 isolate 683620
            SAMN38261939-rid24807223.denovo.106, whole genome shotgun sequence.
ACCESSION   DBEJAU010000106 DBEJAU010000000
VERSION     DBEJAU010000106.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261939
            Sequence Read Archive: SRR26833919
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 1482)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1482)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576303.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576303.1
            Genome Coverage       :: 154x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/19/2025 01:05:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,121
            CDSs (total)                      :: 2,078
            Genes (coding)                    :: 1,943
            CDSs (with protein)               :: 1,943
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 36
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 72 of 135
            Pseudo Genes (incomplete)         :: 63 of 135
            Pseudo Genes (internal stop)      :: 51 of 135
            Pseudo Genes (multiple problems)  :: 46 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1482
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261939-rid24807223.denovo.106"
                     /strain="GPSC323"
                     /isolate="683620"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            complement(<1..1367)
                     /locus_tag="ACL29Z_002073"
     CDS             complement(<1..1367)
                     /locus_tag="ACL29Z_002073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_142291904.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="accessory Sec-dependent serine-rich glycoprotein
                     adhesin"
                     /protein_id="HGR0070313.1"
                     /translation="MFFRRQKGEYRETDRVTRFKLIKSGKHWLRASTSLFGLFKVLRG
                     GVDTTQVMTETVEDKVSHSITGLDILKGIVAAGAVISGTVATQTKVFTNESAVLEKTV
                     EKTDALATNDTVVLGTISTSNSASSTSLSASESASTSASESASTSASTSASTSASESA
                     STSASTSISASSTVVGSQTAAATEATAKKVEEDRKKPASDYVASVTNVNLQSYAKRRK
                     RSVDSIEQLLASIKNAAVFSGNTIVNGAPAINASLNIAKSETKVYTGEGVDSVYRVPI
                     YYKLKVTNDGSKLTFTYTVTYVNPKTNDLGNISSMRPGYSIYNSGTSTQTMLTLGSDL
                     GKPSGVKNYITDKNGRQVLSYNTSTMTTQGSGYTWGNGAQMNGFFAKKGYGLTSSWTV
                     PITGTDTSFTFTPYAARTDRIGINYFNGGGKVVESSTTSQSLSQSKSLSVSASQSASA
                     SASTSA"
BASE COUNT          421 a          308 c          278 g          475 t
ORIGIN      
        1 gcacttgttg atgctgaagc tgaggcgctt tgactagcac ttactgagag tgacttagac
       61 tgtgaaagtg actgactggt cgtgctagat tcaactacct ttcctccacc attgaagtag
      121 ttaattccaa ttctatctgt tctagcagcg taaggggtaa atgtaaagga tgtatccgtt
      181 ccagtaattg gtacagtcca agatgatgtt aatccatatc ctttcttagc aaagaaacca
      241 ttcatttggg caccatttcc ccaagtatac ccactaccct gcgtcgtcat tgtagatgta
      301 ttataggata gaacctgtct accatttttg tcagtaatgt agttctttac acctgaaggt
      361 ttaccaagat cactgccaag ggttaacatt gtttgtgttg aagtacctga attatagata
      421 gaatatccag gacgcatact tgatatatta ccaagatcat ttgttttagg attcacatac
      481 gtaaccgtat aggtaaaggt caattttgaa ccatcatttg tcactttcaa tttatagtaa
      541 attggaacac gatataccga atctacacct tcacctgtat aaacttttgt ctcactttta
      601 gcaatgttta gacttgcatt aattgcaggg gcgccattta caatcgtatt gccagaaaaa
      661 acagcagcat tttttataga agccagcaat tgctcgatgg aatccactga acgcttgcgt
      721 cgcttagcat aagattggag attgacattt gtaactgatg ctacataatc actagctggt
      781 ttcttacgat cttcttcgac cttcttagca gttgcttctg tagcggcagc tgtttgtgaa
      841 cctaccacag tagatgatgc agaaatactt gtcgaagccg atgtacttgc tgattctgat
      901 gcacttgtac ttgctgaggt cgaagcgctg gttgaggctg actcagatgc agatgtactt
      961 gccgactctg aagctgacaa actagttgaa ctcgctgaat tacttgtaga tatcgtacct
     1021 agaactactg tatcatttgt tgccaaagca tccgttttct ctacagtttt ttcaagtact
     1081 gctgactcat ttgtaaatac cttcgtttga gttgcaacgg ttccacttat gacagctccc
     1141 gcagcaacta tccccttgag gatatcaagc ccagtaattg aatgacttac tttatcttct
     1201 accgtttcgg tcatgacctg agtagtatca acaccacctc gcaagacctt aaacaagcca
     1261 aaaagagaag tcgaggcccg tagccaatgc ttccctgatt tgattaattt gaaccgagtt
     1321 actcggtctg tttctctata ttcacccttc tgacgtctaa aaaatatttt gaaatttcct
     1381 ttcgagtatt attttcatgt atggatataa ataaattacc atactataat tatagaatag
     1441 ggaacccaaa atagcaagaa acttgaggta tttttgctaa aa
//
LOCUS       DBEJAU010000107         1269 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC323 isolate 683620
            SAMN38261939-rid24807223.denovo.107, whole genome shotgun sequence.
ACCESSION   DBEJAU010000107 DBEJAU010000000
VERSION     DBEJAU010000107.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261939
            Sequence Read Archive: SRR26833919
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 1269)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1269)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576303.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576303.1
            Genome Coverage       :: 154x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/19/2025 01:05:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,121
            CDSs (total)                      :: 2,078
            Genes (coding)                    :: 1,943
            CDSs (with protein)               :: 1,943
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 36
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 72 of 135
            Pseudo Genes (incomplete)         :: 63 of 135
            Pseudo Genes (internal stop)      :: 51 of 135
            Pseudo Genes (multiple problems)  :: 46 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1269
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261939-rid24807223.denovo.107"
                     /strain="GPSC323"
                     /isolate="683620"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            <1..102
                     /locus_tag="ACL29Z_002074"
     CDS             <1..102
                     /locus_tag="ACL29Z_002074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000690676.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease"
                     /protein_id="HGR0070314.1"
                     /translation="QISSTVLPDIKIKLPIDSRGTPDWNYMERYRDR"
     gene            83..382
                     /locus_tag="ACL29Z_002075"
                     /pseudo
     CDS             83..382
                     /locus_tag="ACL29Z_002075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000224688.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            1066..1227
                     /locus_tag="ACL29Z_002076"
     CDS             1066..1227
                     /locus_tag="ACL29Z_002076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005761276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0070315.1"
                     /translation="MDNDWNGLADLIANLIAKYAGALDLDNLPDPTPAKNQEMKNSFD
                     MAKTQIETD"
BASE COUNT          530 a          160 c          234 g          345 t
ORIGIN      
        1 caaatatcta gcacagtatt gccagatatc aaaattaaat taccgataga cagtagaggt
       61 actccagatt ggaattacat ggaaagatat agagatagat aaagagagag agggagagat
      121 agataaaaag tccaccccca ttttttatgg agaattcaaa aatgtaaggt taagcaaaga
      181 agaatataaa aatctaaaag aaaaattaaa ctcacacaca gatataatga taaataaact
      241 atccagatac atggaaagca gtggtaagac ctatcaaaac cactatgtga caatcttaaa
      301 atggtatgaa gaagataaag acaaactaag acagaaaggt ttaaataaaa aaatgaatta
      361 tgatgtagga gaatctttat agataaaaag aggtggaaag gcactattaa agactttaag
      421 tctaaaaagg tatcaaagta tgccagagat aaaaaaatat aaatatgaca ctttaaaggc
      481 gattagaaaa ttaaagaaat gctagaagac ttttagatga cagttaccaa gagggtctaa
      541 ttttcactgc tacttatgca gtgggaattt gaccttttta tataagcaaa ttctatttca
      601 aaattggtta ccaagaaaga cttcttttca ctgttaagta taagagggta atttatagaa
      661 ttttgttaca ttaagataaa tattttctga tggtcaaatt ttaaaaagat taataactct
      721 cgataaattt tgaaccttaa caattgaata gaccaagaca agacgttaat tatttttgga
      781 gcgtaataac ctatccgtca agatctttcg gctgaataat tcggcaaaaa aagttctgct
      841 aagtaaaaag aaagtgagcg ataagtaaga gtttgaatat agggagggat accctatccg
      901 ctatgaagaa aatgaggata atgatacttc taaggttgaa gccggctcat ctggaataga
      961 ggcggaggtg agattcctat gttgctaatc caaagcactt gtcaatgtca aaaaacttaa
     1021 ttaaacaaat aattattaga tataaaactt tagaggaggt atatattgga caatgactgg
     1081 aatggattgg ctgatttaat agcaaatctg attgcaaaat atgctggtgc tttagattta
     1141 gataatctac ccgatccaac gccagcaaaa aatcaagaga tgaaaaatag ttttgacatg
     1201 gcaaaaacac aaattgagac ggactaataa aagtgttata atatacttga aatgatagtc
     1261 caaacttaa
//
LOCUS       DBEJAU010000108         1262 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC323 isolate 683620
            SAMN38261939-rid24807223.denovo.108, whole genome shotgun sequence.
ACCESSION   DBEJAU010000108 DBEJAU010000000
VERSION     DBEJAU010000108.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261939
            Sequence Read Archive: SRR26833919
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 1262)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1262)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576303.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576303.1
            Genome Coverage       :: 154x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/19/2025 01:05:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,121
            CDSs (total)                      :: 2,078
            Genes (coding)                    :: 1,943
            CDSs (with protein)               :: 1,943
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 36
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 72 of 135
            Pseudo Genes (incomplete)         :: 63 of 135
            Pseudo Genes (internal stop)      :: 51 of 135
            Pseudo Genes (multiple problems)  :: 46 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1262
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261939-rid24807223.denovo.108"
                     /strain="GPSC323"
                     /isolate="683620"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            <1..>1262
                     /locus_tag="ACL29Z_002077"
     CDS             <1..>1262
                     /locus_tag="ACL29Z_002077"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000639856.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0070316.1"
                     /translation="TTNEWLFNFNQEGTVWIWMPKFEISDVDTSYSEAPEDVESQIST
                     VESTFKQRADSLDAGVNRLTEGLRTKVDISALNVTAENIRQSVKSLETDTQNKLNQKL
                     SQAEFEVRAGSIRQEILNATKDKASKSELTQTAEELASKIASVQVGGRNYIRGTKRMM
                     LARGLWASGTFRPSGAGTAKTIDVSDSPATGFDKAIRLTSSNARDQIGIAQDGFHISQ
                     GTYTMSCWVKGRRGQKVKLQTYWQVNDNSGISPIFTLKDENWTKLSFTSARNRAGVAS
                     IGYVYLVNAEVGEYLDVLAPQLEDGSLATSSKEAPEDIEGQISTVESTFKQRANSLDA
                     GVRSLTEGLRTKVDISALNVTAENIRQSVKSLETDTQNKLNQKLSQAEFEVRSGSIRQ
                     EILNATKDKASKSELTQTAEELSSKIASV"
BASE COUNT          399 a          259 c          324 g          280 t
ORIGIN      
        1 accacaaatg aatggttgtt caatttcaac caggaaggaa ccgtttggat ttggatgccg
       61 aagttcgaaa taagcgatgt agatacttct tattcagaag ctcctgaaga tgtcgaaagc
      121 caaatctcaa cagtcgaatc gacctttaaa cagcgtgctg attcactcga cgctggtgtg
      181 aatcgtctga ctgaaggcct tagaaccaaa gtggatatca gcgcactcaa cgtgactgct
      241 gagaatatcc ggcaatctgt gaagagtctt gagacagaca cgcagaacaa gctaaatcag
      301 aagttgagtc aggctgaatt tgaggtgcga gccggctcta tccgtcagga aatcctgaac
      361 gcaaccaagg ataaagccag caagtcagaa ctcacgcaaa cagctgagga actggctagt
      421 aagatagcga gtgtgcaggt cgggggtagg aattatatcc ggggtacaaa gcgcatgatg
      481 ctagccagag gattgtgggc atcaggtact tttagaccgt caggcgctgg gacggcaaag
      541 acgattgatg tatcagacag tccagcaact ggctttgata aagcgatacg attgacctca
      601 agcaatgcta gagaccaaat aggtattgct caagatggat ttcatatctc gcaaggcaca
      661 tacacgatgt cttgttgggt caaaggcaga agaggtcaaa aggtcaagct acaaacttat
      721 tggcaagtca atgataattc gggtatttcg cccatcttta cattaaagga tgaaaattgg
      781 acaaagctat cgtttactag cgctagaaat agggctggag tcgcatcaat tggctatgtg
      841 tatctcgtaa atgctgaggt cggagaatat ttagatgttc ttgcgcccca gctggaagac
      901 ggaagtttgg caacaagctc aaaagaagct cctgaagata tagaaggtca gatttcaaca
      961 gttgaatcga ccttcaaaca acgagccaac tcgctcgacg ctggtgtaag aagcttgact
     1021 gaagggctta gaactaaagt ggatatcagc gcactcaacg tgactgctga aaatatccgg
     1081 caatctgtga agagccttga gacagacacg cagaacaagc taaatcagaa gttgagtcag
     1141 gctgaatttg aggtgcgatc cggctctatc cgtcaggaaa tcctgaacgc aaccaaggat
     1201 aaagccagca agtcagaact cacgcagaca gctgaggaac tctctagtaa gatagcgagt
     1261 gt
//
LOCUS       DBEJAU010000109         1223 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC323 isolate 683620
            SAMN38261939-rid24807223.denovo.109, whole genome shotgun sequence.
ACCESSION   DBEJAU010000109 DBEJAU010000000
VERSION     DBEJAU010000109.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261939
            Sequence Read Archive: SRR26833919
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 1223)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1223)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576303.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576303.1
            Genome Coverage       :: 154x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/19/2025 01:05:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,121
            CDSs (total)                      :: 2,078
            Genes (coding)                    :: 1,943
            CDSs (with protein)               :: 1,943
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 36
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 72 of 135
            Pseudo Genes (incomplete)         :: 63 of 135
            Pseudo Genes (internal stop)      :: 51 of 135
            Pseudo Genes (multiple problems)  :: 46 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1223
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261939-rid24807223.denovo.109"
                     /strain="GPSC323"
                     /isolate="683620"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            <1..69
                     /locus_tag="ACL29Z_002078"
     CDS             <1..69
                     /locus_tag="ACL29Z_002078"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004264816.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SapB/AmfS family lantipeptide"
                     /protein_id="HGR0070317.1"
                     /translation="MRFSTFSTNRCGNWSAFSWENC"
     gene            871..1170
                     /locus_tag="ACL29Z_002079"
                     /pseudo
     CDS             871..1170
                     /locus_tag="ACL29Z_002079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000869756.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
BASE COUNT          383 a          173 c          256 g          411 t
ORIGIN      
        1 atgcgattta gtacattcag tacaaaccgt tgcggtaact ggagtgcttt tagttgggaa
       61 aattgttaat tcatttaaat tgtaaacttt agggattctc tggagttatg gatgtcgttc
      121 caatatgtgt acgttggaat attagtgctt atatgggggg aacagaatcc tctcttgatt
      181 gaagacaagc tagccattag gctggtttgt ctttttgtct ctttgtcaac tgtagtgggt
      241 tgatataata gtattagtga atgggataaa agtttcattt agtttattca gtacaaattt
      301 aacgggtcaa gatttatata ctggtggtgt ttttggggct gagagaagta tcttgatttt
      361 atgtgtggtt tttatactta cagttgttct gctccaaaga gcttgtagag aagaattagc
      421 tcataaagga gattgattat tttgatatca aaaaaatgca caggataacc tgatgcattt
      481 ttttagcgac aatgcttgct acttccttct gtcgaattta gacaatttta aataaaagaa
      541 tgaaatattc cctactgtat ttttagacga agaacgttag ttaataatac tcaaatttat
      601 ttcaaactct ttgattagta tgaatttagc tctacagaaa aataaaaaat gtgataaaaa
      661 tttcaactac tcttatctat aataaagcta cctgttcttt gaaaattgaa tccactccgt
      721 cttgattagc gtgcctgtgt aagtagggac tgagagtatt tccctgtgaa gggcaactgg
      781 cacaagacgt gtgtgagaat tttctaacag acacggagtt tatcgtttcc agactcaaac
      841 gatgcgacaa actagataaa ggagttaatc atgaaggtag taaacttgta tgatttgaaa
      901 caaatgggaa ataaaggtgg ttgtaccatc caattgattc atcactttcc ttttggtatg
      961 ggcttaggac atctcaaaaa agactacatt gagtttaaac atgttggtat ctttgatggg
     1021 aaagcagtag aagttactct tcgataacct tattcgagag atctactgca ggttgtcaag
     1081 tcgattaagc aacgtcagaa attgatagct tatcgttata aagaaggaaa gctgctattt
     1141 gttaagaagg aggcatcaga tgtcctctga acaacaggaa cgaatggcag ttcaatatgc
     1201 agagcgtagt cttttattta ctg
//
LOCUS       DBEJAU010000110         1171 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC323 isolate 683620
            SAMN38261939-rid24807223.denovo.110, whole genome shotgun sequence.
ACCESSION   DBEJAU010000110 DBEJAU010000000
VERSION     DBEJAU010000110.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261939
            Sequence Read Archive: SRR26833919
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 1171)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1171)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576303.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576303.1
            Genome Coverage       :: 154x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/19/2025 01:05:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,121
            CDSs (total)                      :: 2,078
            Genes (coding)                    :: 1,943
            CDSs (with protein)               :: 1,943
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 36
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 72 of 135
            Pseudo Genes (incomplete)         :: 63 of 135
            Pseudo Genes (internal stop)      :: 51 of 135
            Pseudo Genes (multiple problems)  :: 46 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1171
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261939-rid24807223.denovo.110"
                     /strain="GPSC323"
                     /isolate="683620"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            complement(<1..374)
                     /locus_tag="ACL29Z_002080"
     CDS             complement(<1..374)
                     /locus_tag="ACL29Z_002080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001232094.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0070318.1"
                     /translation="MRKSGFLIYYVLFCIVCFLLGLLLSFILKNETFATIPPKLELQF
                     TLTVLQANSTNFLLYLFCFPISPLLQLFDLLSLGIQLGISGQMIGIVATIKGILPHAL
                     IEIPNFIWYQGMSQYLLYRLLK"
     gene            complement(371..>1171)
                     /locus_tag="ACL29Z_002081"
     CDS             complement(371..>1171)
                     /locus_tag="ACL29Z_002081"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000698829.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0070319.1"
                     /translation="IGYFYLSITLCLIAIQIISLILPSLFSIISKLFLFLSIGLLSIE
                     QGQVVIYVILLNYFILVMGILDNHASNFYFKSSRMSQKRFRSSLFILLRFCWLNKGLT
                     FSFILISILLSYLFWYMMTMLSIDDTKIPILFLYTSIYITLMEAIIGNHKSSIGVDLA
                     LLQLSALNHSKMNFFFKNAQLMMLTHLISFLQFSLLLCLIPVTSYSNDIKSILLNLLL
                     IPFNYFIAYVYYKKALFLIKGTVSLLRWSFLVLYCFLIIFVILVGGIR"
BASE COUNT          506 a          175 c          142 g          348 t
ORIGIN      
        1 tccttcaata atcggtataa aagatactga ctcatacctt gataccaaat aaaattcggt
       61 atttcaataa gagcatgagg taatattcct tttattgtag ctactattcc aatcatctga
      121 ccagatatac ccaattgtat tcctaaagat agcaaatcaa aaagttgcaa taagggcgaa
      181 atcggaaaac agaatagata tagcaaaaaa tttgtagaat ttgcctgtaa aactgtcaat
      241 gtaaattgta attccagttt cggaggtata gtagcaaaag tctcattttt taatataaag
      301 cttaaaagta aacctagtaa aaaacagact atacaaaata acacatagta aatcagaaaa
      361 ccactttttc tcatctaatg ccccctacta aaattacaaa tattatcaga aaacaatata
      421 aaaccagaaa actccatctc aataaactaa ctgtaccttt aattaaaaat agagctttct
      481 tataatagac ataggctata aaataattga atggaatcaa taacaaattc aacaaaatac
      541 tttttatatc attactataa cttgtcaccg gaatcaaaca taacaacaat gaaaattgta
      601 agaaagagat taaatgcgtc aacatcatta gttgtgcatt cttaaaaaag aaattcattt
      661 tagaatgatt aagagcagat aattgaagta aagctagatc taccccaatt gaggatttat
      721 gattccctat tattgcctcc attaatgtaa tatatattga ggtataaaga aataatattg
      781 gtatttttgt gtcatcaatt gataacatcg tcatcatata ccaaaataga taggaaagaa
      841 gaatactaat caaaataaaa gaaaaagtta accctttatt taaccaacaa aaacgaagca
      901 atataaatag actgctacga aatctttttt gactcattcg actgctttta aaatagaaat
      961 tactcgcatg attatctaat atccccatga ctaaaataaa ataattgagt agtatgacat
     1021 aaattacaac ttgtccttgt tctatagaca atagtcctat agataaaaat aagaacaatt
     1081 tacttataat tgaaaacaaa ctaggtagaa ttaaagaaat aatttgaata gctatcaaac
     1141 aaagagtaat ggataaataa aaatatccaa t
//
LOCUS       DBEJAU010000111         1137 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC323 isolate 683620
            SAMN38261939-rid24807223.denovo.111, whole genome shotgun sequence.
ACCESSION   DBEJAU010000111 DBEJAU010000000
VERSION     DBEJAU010000111.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261939
            Sequence Read Archive: SRR26833919
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 1137)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1137)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576303.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576303.1
            Genome Coverage       :: 154x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/19/2025 01:05:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,121
            CDSs (total)                      :: 2,078
            Genes (coding)                    :: 1,943
            CDSs (with protein)               :: 1,943
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 36
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 72 of 135
            Pseudo Genes (incomplete)         :: 63 of 135
            Pseudo Genes (internal stop)      :: 51 of 135
            Pseudo Genes (multiple problems)  :: 46 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1137
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261939-rid24807223.denovo.111"
                     /strain="GPSC323"
                     /isolate="683620"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            644..1024
                     /locus_tag="ACL29Z_002082"
     CDS             644..1024
                     /locus_tag="ACL29Z_002082"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000424421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SP_0115 family bacteriocin-like peptide"
                     /protein_id="HGR0070320.1"
                     /translation="MELVLPNNYVALEQEEMMYLDGGGVGRNWWNSRGSFATVLDVDL
                     AIYSGGATIYSAYAIKKAISANRGAITRTLRSLIIKHVGSAAGHLVNTALNVALTVTG
                     FSLGGAIAYGADWADGSLDGYIFA"
BASE COUNT          381 a          127 c          236 g          393 t
ORIGIN      
        1 tacttgacag ttattatatt ttcacttatt atatagataa aaggatggga taggagttta
       61 aaaatttgaa agcgctatcc ataatcataa cgcataattt tctccttttc gtgaaaaaag
      121 ttaacgtaat tttgaaatga gcttaataag aggtatgatg taggtagaaa ataaagatag
      181 gagaaaaagt atgaataaaa aaatattttg tattctagta tgtattatat cattgattag
      241 tctagctata atctttccat ggggctggtc gatataatgt aagggagctt gagttgttag
      301 tggaggataa aatgttaaga gtaatagtag ttattcaatc tttagtaata atactgcttg
      361 ctgttgcttt attattatct cggaaaaact ttgattcgtt aaatgttgtt cttataatga
      421 tgatcgtatc acaattgttg ttattagtat atttgataaa atcagggaat cagtgattag
      481 ctgttatttg aattaagtaa actgttaagc ttcaagcagt aactggtttt aaatatttaa
      541 aataagataa aggaaggaag tctaatttag gtaactaaac aaagcctgcg atcacttgtt
      601 aggaaaccat cctaaccatg cttaataaaa aaggagaaaa taaatggaac tcgtattacc
      661 aaataattat gttgctcttg agcaagaaga gatgatgtat cttgatgggg gtggtgttgg
      721 tcgtaactgg tggaatagta gaggtagttt tgcaacagtt ctggatgtag atttggccat
      781 ctatagtggt ggtgcaacaa tttattctgc ttatgcgata aaaaaagcta tctcagctaa
      841 tagaggggct attacgagaa cattacgtag tttaataatt aaacatgtag gtagtgcagc
      901 tggccattta gtcaatactg cactaaacgt tgcactaact gttactggat tttcactagg
      961 tggagcaatc gcatatgggg ctgattgggc tgacggtagc ttagatggtt atatttttgc
     1021 ttaaaatgaa acattttttt gcaggaattg gtgaaataaa ctttgtaagt tatttattgt
     1081 atatatgtgt aggaatagcc cctttttttc acgtatatat aataggttct gaaatga
//
LOCUS       DBEJAU010000112         1079 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC323 isolate 683620
            SAMN38261939-rid24807223.denovo.112, whole genome shotgun sequence.
ACCESSION   DBEJAU010000112 DBEJAU010000000
VERSION     DBEJAU010000112.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261939
            Sequence Read Archive: SRR26833919
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 1079)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1079)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576303.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576303.1
            Genome Coverage       :: 154x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/19/2025 01:05:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,121
            CDSs (total)                      :: 2,078
            Genes (coding)                    :: 1,943
            CDSs (with protein)               :: 1,943
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 36
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 72 of 135
            Pseudo Genes (incomplete)         :: 63 of 135
            Pseudo Genes (internal stop)      :: 51 of 135
            Pseudo Genes (multiple problems)  :: 46 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1079
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261939-rid24807223.denovo.112"
                     /strain="GPSC323"
                     /isolate="683620"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            complement(30..119)
                     /locus_tag="ACL29Z_002083"
     tRNA            complement(30..119)
                     /locus_tag="ACL29Z_002083"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(81..83),aa:Ser,seq:tga)
     gene            complement(130..203)
                     /locus_tag="ACL29Z_002084"
     tRNA            complement(130..203)
                     /locus_tag="ACL29Z_002084"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(167..169),aa:Ile,seq:cat)
     gene            complement(217..290)
                     /locus_tag="ACL29Z_002085"
     tRNA            complement(217..290)
                     /locus_tag="ACL29Z_002085"
                     /product="tRNA-Met"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(254..256),aa:Met,seq:cat)
     gene            complement(296..369)
                     /locus_tag="ACL29Z_002086"
     tRNA            complement(296..369)
                     /locus_tag="ACL29Z_002086"
                     /product="tRNA-Pro"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(333..335),aa:Pro,seq:tgg)
     gene            complement(385..458)
                     /locus_tag="ACL29Z_002087"
     tRNA            complement(385..458)
                     /locus_tag="ACL29Z_002087"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(422..424),aa:Arg,seq:acg)
     gene            complement(468..553)
                     /locus_tag="ACL29Z_002088"
     tRNA            complement(468..553)
                     /locus_tag="ACL29Z_002088"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(517..519),aa:Leu,seq:taa)
     gene            complement(561..632)
                     /locus_tag="ACL29Z_002089"
     tRNA            complement(561..632)
                     /locus_tag="ACL29Z_002089"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(598..600),aa:Gly,seq:gcc)
     gene            complement(655..727)
                     /locus_tag="ACL29Z_002090"
     tRNA            complement(655..727)
                     /locus_tag="ACL29Z_002090"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(692..694),aa:Thr,seq:tgt)
     gene            complement(746..827)
                     /locus_tag="ACL29Z_002091"
     tRNA            complement(746..827)
                     /locus_tag="ACL29Z_002091"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(791..793),aa:Leu,seq:tag)
     gene            complement(833..905)
                     /locus_tag="ACL29Z_002092"
     tRNA            complement(833..905)
                     /locus_tag="ACL29Z_002092"
                     /product="tRNA-Lys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(870..872),aa:Lys,seq:ttt)
     gene            complement(930..1002)
                     /locus_tag="ACL29Z_002093"
     tRNA            complement(930..1002)
                     /locus_tag="ACL29Z_002093"
                     /product="tRNA-Asp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(967..969),aa:Asp,seq:gtc)
     gene            complement(1005..1077)
                     /locus_tag="ACL29Z_002094"
     tRNA            complement(1005..1077)
                     /locus_tag="ACL29Z_002094"
                     /product="tRNA-Val"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(1042..1044),aa:Val,seq:tac)
BASE COUNT          277 a          314 c          246 g          242 t
ORIGIN      
        1 gctgctccat cccgcgttaa taatataaaa ggaggatgtg ggattcgaac ccacgcacgc
       61 ttttacacgc ctgacggttt tcaagaccgt tcccttcagc cggacttggg taatcctcca
      121 atattcaaat ggaccttgta ggacttgaac ctacgaccac tcggttatga gccgagagct
      181 ctaaccagct gagctaaagg tccgacaaga tcattatagc ggcgaagggg atcgaacccc
      241 cgacctcccg ggtatgaacc ggacgctcta gccagctgag ctacaccgcc atgaatcggg
      301 aagacaggat tcgaacctgc gacaccttgg tcccaaacca agtactctac caagctgagc
      361 tacttcccga gttaaataga aaaatgcacc ctagaggagt cgaacctcta accgcctgat
      421 tcgtagtcag gtactctatc cagttgagct aagggtgctc catattatgc cgaggaccgg
      481 aatcgaaccg gtacgatcgt taccaatcgc aggattttaa gtcctgtgcg tctgccagtt
      541 ccgccacccc ggcctctcta agcgaacgac gggattcgaa cccgcgaccc ccaccttggc
      601 aaggtggtgt tctaccactg aactacgttc gcgctgtttt cttctatcta aaaatgccgg
      661 ctacatgact tgaacacgcg accctctgat tacaaatcag atgctctacc aactgagcta
      721 agccggctca tttgttatat cttaatgcgg gttaagggac ttgaaccccc acgccgttaa
      781 gcgccagatc ctaaatctgg tgcgtctgcc aattccgcca aacccgcata tatgacccgt
      841 actgggctcg aaccagtgac ccattgatta aaagtcaatt gctctaccaa ctgagctaac
      901 gagtctaaaa taacttgcgt taccttaaac ggtcccgacg ggaatcgaac ccgcgatctt
      961 cgccgtgaca gggcgacgtg ataaccgcta cactacggga cctttgggag ttaacgggat
     1021 cgaaccgctg accctctgct tgtaaggcag atgctctccc agctgagcta aactcccta
//
LOCUS       DBEJAU010000113         1014 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC323 isolate 683620
            SAMN38261939-rid24807223.denovo.113, whole genome shotgun sequence.
ACCESSION   DBEJAU010000113 DBEJAU010000000
VERSION     DBEJAU010000113.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261939
            Sequence Read Archive: SRR26833919
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 1014)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1014)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576303.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576303.1
            Genome Coverage       :: 154x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/19/2025 01:05:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,121
            CDSs (total)                      :: 2,078
            Genes (coding)                    :: 1,943
            CDSs (with protein)               :: 1,943
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 36
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 72 of 135
            Pseudo Genes (incomplete)         :: 63 of 135
            Pseudo Genes (internal stop)      :: 51 of 135
            Pseudo Genes (multiple problems)  :: 46 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1014
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261939-rid24807223.denovo.113"
                     /strain="GPSC323"
                     /isolate="683620"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            228..>1014
                     /locus_tag="ACL29Z_002095"
     CDS             228..>1014
                     /locus_tag="ACL29Z_002095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-amylase family glycosyl hydrolase"
                     /protein_id="HGR0070321.1"
                     /translation="MDNREALKTFMTGENFYLQHYLGAHREELNGEHGYTFRVWAPNA
                     QAVHLVGDFTNWIENQIPMVRNDFGVWEVFTNMAQEGHIYKYHVTRQNGHQLMKIDPV
                     AVRYEARPGTGAIVTELPDKKWRDGLWLARRKRWGFAERPVNIYEVHAGSWKRNPDGS
                     PYSFAQLKDELIPYLVEMNYTHIEFMPLMSHPLGLSWGYQLMGYFALEHAYGRPEEFQ
                     DFVEECHTHNIGVIVDWVPGHFTINDDALAYYDGTPTFEYQDHN"
BASE COUNT          304 a          170 c          233 g          307 t
ORIGIN      
        1 ttgactgtcc tgatcgattt gcgcatgttt tatttcattt cactatagta gaaaaagaaa
       61 ggcgttttcg caattttttg aaaaaatatt gatttacaat tgaacgagta agtgaacttg
      121 ttgtagattt tcaaaataat taaagaagta tagtaattta cttgaatctt ctctaaaaag
      181 gtagtataat aaaaacatag aaaacgctta caggagaagg ggagtatatg gataatagag
      241 aagcattaaa aacctttatg acgggtgaaa atttttatct ccaacattat ctaggagcac
      301 atagggaaga actaaatgga gagcatggct ataccttccg tgtttgggca cctaatgctc
      361 aggctgttca cttggttggt gattttacca actggattga aaatcagatt ccaatggtaa
      421 gaaatgactt tggggtctgg gaagtcttta ccaatatggc tcaagaaggg catatttaca
      481 aatatcatgt cacacgtcaa aatggtcatc aactgatgaa gattgaccct gttgctgtca
      541 ggtatgaggc tcgtccagga acaggggcaa tcgtaacaga gcttcctgat aagaaatgga
      601 gggatggact ttggctggca cgaagaaaac gttggggctt tgctgaacgt cctgtcaata
      661 tttacgaggt tcatgctggc tcttggaaga gaaatcctga tggcagtcct tatagttttg
      721 cccagctcaa ggatgaactc attccttatc tcgttgaaat gaactatact catattgagt
      781 ttatgccctt gatgtcccat cctttgggct tgagttgggg gtatcagctt atgggttact
      841 tcgctttaga gcatgcttat ggcagaccag aggagtttca agattttgtc gaggagtgtc
      901 atacccataa tattggggtt attgtggact gggtaccagg tcactttacc atcaacgatg
      961 atgccttagc ctattatgat gggacaccga cttttgaata ccaagaccat aata
//
LOCUS       DBEJAU010000114          973 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC323 isolate 683620
            SAMN38261939-rid24807223.denovo.114, whole genome shotgun sequence.
ACCESSION   DBEJAU010000114 DBEJAU010000000
VERSION     DBEJAU010000114.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261939
            Sequence Read Archive: SRR26833919
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 973)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 973)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576303.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576303.1
            Genome Coverage       :: 154x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/19/2025 01:05:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,121
            CDSs (total)                      :: 2,078
            Genes (coding)                    :: 1,943
            CDSs (with protein)               :: 1,943
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 36
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 72 of 135
            Pseudo Genes (incomplete)         :: 63 of 135
            Pseudo Genes (internal stop)      :: 51 of 135
            Pseudo Genes (multiple problems)  :: 46 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..973
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261939-rid24807223.denovo.114"
                     /strain="GPSC323"
                     /isolate="683620"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            complement(<1..115)
                     /locus_tag="ACL29Z_002096"
     CDS             complement(<1..115)
                     /locus_tag="ACL29Z_002096"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001017606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose 6-dehydrogenase"
                     /protein_id="HGR0070322.1"
                     /translation="MNIAVIGLGHVGLAYALLFASKYKVVAYDIDSVKINNL"
     gene            complement(128..877)
                     /locus_tag="ACL29Z_002097"
     CDS             complement(128..877)
                     /locus_tag="ACL29Z_002097"
                     /EC_number="3.5.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000069862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0019213 - deacetylase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PIG-L family deacetylase"
                     /protein_id="HGR0070323.1"
                     /translation="MSNNTKYIFLSPHLDDAIFSCGDYISKLTSEGEIVLVITIFSGY
                     PLSQQLQPSAKQFHKLCNLGKYPIEERKKEDRLACERLQCDFRHLSYYECLYRKDRNG
                     NFLYRHIYSELKNEDTLKNDIIKELLMHLDDKCVVYCPLSLGDHVDHVFVNSIGRALE
                     FMRYKVIYYEDFPYVSDSSMVSYMGKTKELKMYQEELDEKHYIDRISSILCYKSQILI
                     IWKSVEKLLNNIKELYLRNGAAYSIRFWIKK"
BASE COUNT          338 a          188 c          108 g          339 t
ORIGIN      
        1 ttaaattatt tatttttaca gaatctatat catatgcaac aactttatat ttagatgcaa
       61 atagtaacgc gtaggccagc ccaacatgcc ccaaaccaat tactgctata ttcataaaac
      121 tacttcctta tttcttaatc caaaatctaa tagaataagc tgccccattc cttaaataca
      181 actctttaat attgtttaaa agtttttcaa ctgatttcca gattatcaaa atctgagatt
      241 tatagcacaa tattgatgat attctatcaa tataatgttt ttcatcaagt tcctcttgat
      301 acatttttaa ttctttagtt tttcccatat aactaaccat actactatca cttacatatg
      361 ggaagtcctc ataatatatt actttataac gcataaattc aagcgccctt ccaatactat
      421 tcacaaaaac atgatcaaca tggtcaccaa gtgaaagcgg acaatatacg acacatttgt
      481 cgtctaaatg cattaacagc tcttttatga tatcattctt taatgtgtcc tcatttttta
      541 attcactata gatatgacgg tatagaaaat tgccatttct atctttccta tagagacatt
      601 catagtacga taagtgtcta aaatcacatt gtagacgttc acaagctaac ctgtcttctt
      661 tcttcctttc ttcaatcgga tatttcccaa ggttacacaa cttatgaaat tgcttagcag
      721 agggctgtag ctgttggctc aaagggtaac cagaaaatat agtaataaca agtacaattt
      781 ctccttctga agttaatttt gaaatataat caccacagga aaaaattgcg tcatctaaat
      841 gtggagataa aaagatatac ttagtattgt tactcataac cattccctct acaatttatc
      901 taaaaactca ctaagtgtct gattaaattc cacatcatca aaaaaattca ccttattctt
      961 aataatgaat att
//
LOCUS       DBEJAU010000115          855 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC323 isolate 683620
            SAMN38261939-rid24807223.denovo.115, whole genome shotgun sequence.
ACCESSION   DBEJAU010000115 DBEJAU010000000
VERSION     DBEJAU010000115.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261939
            Sequence Read Archive: SRR26833919
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 855)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 855)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576303.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576303.1
            Genome Coverage       :: 154x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/19/2025 01:05:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,121
            CDSs (total)                      :: 2,078
            Genes (coding)                    :: 1,943
            CDSs (with protein)               :: 1,943
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 36
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 72 of 135
            Pseudo Genes (incomplete)         :: 63 of 135
            Pseudo Genes (internal stop)      :: 51 of 135
            Pseudo Genes (multiple problems)  :: 46 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..855
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261939-rid24807223.denovo.115"
                     /strain="GPSC323"
                     /isolate="683620"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            <1..>855
                     /locus_tag="ACL29Z_002098"
     CDS             <1..>855
                     /locus_tag="ACL29Z_002098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001808790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IS1380-like element ISSpn5 family transposase"
                     /protein_id="HGR0070324.1"
                     /translation="YGTDYACKELSADAYFPKLLEGGQLASQPTLSRFLSRTDEETVH
                     SLRCLNLELVEFFLQFHQLNQLIVDIDSTHFTTYGKQEGVAYNAHYRAHGYHPLYAFE
                     GKTGYCFNAQLRPGNRYCSEEADSFITPVLERFNQLLFRMDSGFATPKLYDLIEKTGQ
                     YYLIKLKKNTVLSRLGDLSLPCPQDEDLTILPHSAYSETLYQAGSWSHKRRVCQFSER
                     KEGNLFYDVISLVTNMTSGTSQDQFQLYRGRGQAENFIKEMKEGFFGDKTDSSTLIKN
                     EVRMMMSCI"
BASE COUNT          240 a          192 c          174 g          249 t
ORIGIN      
        1 tatggaacgg actatgcttg taaagaattg tcagctgatg cctactttcc aaaattgttg
       61 gaaggagggc agcttgcttc acagccaacc ttatcccgtt ttctttccag aactgacgag
      121 gaaacagtcc atagtttgcg atgcctcaac cttgaattgg tcgaattctt tttacagttt
      181 caccagctaa accaactcat tgtagatatc gattctaccc atttcacaac ttatggcaag
      241 caagaaggtg ttgcttataa cgctcactat cgtgctcatg gctatcatcc tctttatgct
      301 ttcgagggga agacaggtta ttgtttcaat gcccagcttc gtcctggtaa tcgttattgt
      361 tctgaagagg cagacagctt tatcacacct gttttagaac ggtttaatca acttctcttt
      421 cgaatggata gtggctttgc gaccccaaaa ttatacgatt taattgaaaa aacagggcaa
      481 tactacctca taaaactcaa gaaaaatact gttctgagcc gtcttggaga cctttccctc
      541 ccttgcccac aggatgagga cttaaccatc ttgccccact ccgcctactc agaaactctc
      601 tatcaagcag gatcttggtc gcacaagcgt cgtgtctgcc agttctctga acgaaaagaa
      661 ggaaacttgt tctacgatgt tatttctctc gttacaaata tgacgagtgg aacaagccaa
      721 gaccagtttc agctttatcg tggacgtggt caagccgaga atttcatcaa ggagatgaag
      781 gagggatttt ttggcgataa aacggatagt tcaaccttaa tcaaaaacga agttcgtatg
      841 atgatgagct gtatc
//
LOCUS       DBEJAU010000116          829 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC323 isolate 683620
            SAMN38261939-rid24807223.denovo.116, whole genome shotgun sequence.
ACCESSION   DBEJAU010000116 DBEJAU010000000
VERSION     DBEJAU010000116.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261939
            Sequence Read Archive: SRR26833919
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 829)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 829)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576303.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576303.1
            Genome Coverage       :: 154x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/19/2025 01:05:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,121
            CDSs (total)                      :: 2,078
            Genes (coding)                    :: 1,943
            CDSs (with protein)               :: 1,943
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 36
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 72 of 135
            Pseudo Genes (incomplete)         :: 63 of 135
            Pseudo Genes (internal stop)      :: 51 of 135
            Pseudo Genes (multiple problems)  :: 46 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..829
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261939-rid24807223.denovo.116"
                     /strain="GPSC323"
                     /isolate="683620"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            15..>829
                     /gene="dinB"
                     /locus_tag="ACL29Z_002099"
     CDS             15..>829
                     /gene="dinB"
                     /locus_tag="ACL29Z_002099"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000904550.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003684 - damaged DNA binding [Evidence
                     IEA];
                     GO_function: GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase IV"
                     /protein_id="HGR0070325.1"
                     /translation="MLIFPLLNDLSRKIIHIDMDAFFAAVEIRDNPKLRGKPVIIGSD
                     PRQTGGRGVVSTCSYEARAFGVHSAMSSKEAYERCPQAVFISGNYEKYKSVGLQIRAI
                     FKRYTDLIEPMSIDEAYLDVTENKLGIKSAVKIARLIQKDIWQELHLTASAGVSYNKF
                     LAKMASDYQKPHGLTVILPEQAEDFLKQMDISKFHGVGKKTVERLHQMGVFTGADLLE
                     VPEVTLIDRFGRLGYDLYRKARGIHNSPVKSNRIRKSIGKEKTYGKILLAEED"
BASE COUNT          249 a          162 c          183 g          235 t
ORIGIN      
        1 aaaaggtgct aggcatgttg atttttcctt tgttaaatga tttgtcaaga aaaatcatcc
       61 atattgacat ggatgccttt tttgctgcag tggaaatcag ggataatcct aaactcagag
      121 gaaaacctgt cattattgga agcgaccctc ggcaaacagg tggacgggga gtcgtttcta
      181 cctgtagtta tgaggcaaga gcttttggtg tccattctgc catgagttcc aaggaagctt
      241 atgaacgttg tccccaggct gtctttatct cagggaatta tgagaaatac aagtctgtgg
      301 gactccagat tcgagctatt tttaagcgct atacagattt gattgaaccc atgagcattg
      361 acgaagccta tttggatgtg acagaaaata aactcggtat caagtcagcg gtcaaaattg
      421 ctcgcctcat tcaaaaagat atctggcaag aactccatct aactgcttcc gcaggcgttt
      481 cttacaacaa attcttagct aaaatggcga gtgattatca aaaaccacat ggtttgacag
      541 tgattctacc tgaacaggct gaggattttc tcaaacaaat ggatatttcc aaatttcatg
      601 gagtaggaaa aaagacagta gaacgtcttc atcaaatggg cgtttttact ggtgctgatt
      661 tacttgaagt tcctgaggta accctaatag accgttttgg tagactaggc tatgatctgt
      721 atcgaaaggc tcgtggcatt cacaactctc cagtcaaatc caatcgcatc cgtaaatcaa
      781 tcggcaagga gaaaacctac gggaagattc tccttgctga ggaagatat
//
LOCUS       DBEJAU010000117          795 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC323 isolate 683620
            SAMN38261939-rid24807223.denovo.117, whole genome shotgun sequence.
ACCESSION   DBEJAU010000117 DBEJAU010000000
VERSION     DBEJAU010000117.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261939
            Sequence Read Archive: SRR26833919
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 795)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 795)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576303.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576303.1
            Genome Coverage       :: 154x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/19/2025 01:05:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,121
            CDSs (total)                      :: 2,078
            Genes (coding)                    :: 1,943
            CDSs (with protein)               :: 1,943
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 36
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 72 of 135
            Pseudo Genes (incomplete)         :: 63 of 135
            Pseudo Genes (internal stop)      :: 51 of 135
            Pseudo Genes (multiple problems)  :: 46 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..795
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261939-rid24807223.denovo.117"
                     /strain="GPSC323"
                     /isolate="683620"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            1..795
                     /locus_tag="ACL29Z_002100"
                     /pseudo
     CDS             1..795
                     /locus_tag="ACL29Z_002100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000436393.1"
                     /note="frameshifted; incomplete; missing N-terminus and
                     C-terminus; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=3
                     /transl_table=11
                     /product="transposase"
BASE COUNT          236 a          169 c          144 g          246 t
ORIGIN      
        1 ctagaattct ccttagaaaa cgccgtttca agtgctatca ctgttcaaaa atgatggtcg
       61 ctgaaacttc tatcgtcaag aagaatcatc aaattcctcg tattatcaac caaaaaattg
      121 cgcaaaagtt gattgagaag atttctatga ccgatattgc tcatcagctg gccatttcaa
      181 cttcaactgt cattcgcaag ctcaatgatt ctcactttga gcatgatttt tcgcgtcttc
      241 ctgagattat gtcctgggac gttgaaacag tccggggagt gactgtttca atcgggagat
      301 ggagatgagc tttattgcgc aagattttaa caatctcaat atcatcactg ttcttgaagg
      361 tagaacacaa gctgtcatcc gagatcactt tcttaaatat gatagatccg tccgatgtcg
      421 cgtcaaaatc attactatgg atatgtttag cccttactat gacttggcta aacagcttcg
      481 ctttcaaatt tctaggctca ggctgaaaca gtctcctaat gctaaaatcg ttcttgactg
      541 ctttcatatt gtacaacatc ttagccgtgc tatgagtcgt gtgcgtgtcc aaatcatgaa
      601 tcagtttcat cgaaaatccc atgaatacaa ggctatcaag cgctactgga aactcattca
      661 acaggatagc tgtaaactga gtgataagcg attttatcgt cctatttttc gtatgcactt
      721 aaccaataaa gagattttaa acaagctttt gagctattcg gaagacttga aacaccacta
      781 tcaactctat cagct
//
LOCUS       DBEJAU010000118          733 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC323 isolate 683620
            SAMN38261939-rid24807223.denovo.118, whole genome shotgun sequence.
ACCESSION   DBEJAU010000118 DBEJAU010000000
VERSION     DBEJAU010000118.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261939
            Sequence Read Archive: SRR26833919
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 733)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 733)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576303.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576303.1
            Genome Coverage       :: 154x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/19/2025 01:05:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,121
            CDSs (total)                      :: 2,078
            Genes (coding)                    :: 1,943
            CDSs (with protein)               :: 1,943
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 36
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 72 of 135
            Pseudo Genes (incomplete)         :: 63 of 135
            Pseudo Genes (internal stop)      :: 51 of 135
            Pseudo Genes (multiple problems)  :: 46 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..733
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261939-rid24807223.denovo.118"
                     /strain="GPSC323"
                     /isolate="683620"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            complement(<1..96)
                     /gene="rrf"
                     /locus_tag="ACL29Z_002101"
     rRNA            complement(<1..96)
                     /gene="rrf"
                     /locus_tag="ACL29Z_002101"
                     /product="5S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00001"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00001"
     gene            complement(173..>733)
                     /locus_tag="ACL29Z_002102"
     rRNA            complement(173..>733)
                     /locus_tag="ACL29Z_002102"
                     /product="23S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF02541"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF02541"
BASE COUNT          168 a          214 c          156 g          195 t
ORIGIN      
        1 cacagggggc aacccccaac tacttccggc gttctagggc ttaacttctg tgttcggcat
       61 gggtacaggt gtatctccta ggctatcgtc acttaactct gagtaatacc tactcaaaat
      121 tgaatatcta ttcaacttaa gaaaaccgtt cgctttcata ttctcagtta ctttggataa
      181 gtcctcgagc tattagtatt agtccgctac atgtgtcgcc acacttccac ttctaaccta
      241 tctacctgat catctctcag ggctcttact gatatataat catgggaaat ctcatcttga
      301 ggtgggtttc acacttagat gctttcagcg tttatccctt ccctacatag ctacccagcg
      361 atgcctttgg caagacaact ggtacaccag cggtaagtcc actctggtcc tctcgtacta
      421 ggagcagatc ctctcaaatt tcctacgccc gcgacggata gggaccgaac tgtctcacga
      481 cgttctgaac ccagctcgcg tgccgcttta atgggcgaac agcccaaccc ttgggaccga
      541 ctacagcccc aggatgcgac gagccgacat cgaggtgcca aacctccccg tcgatgtgaa
      601 ctcttggggg agataagcct gttatcccca gggtagcttt tatccgttga gcgatggccc
      661 ttccatacgg aaccaccgga tcactaagcc cgactttcgt ccctgctcga gttgtagctc
      721 tcgcagtcaa gct
//
LOCUS       DBEJAU010000119          681 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC323 isolate 683620
            SAMN38261939-rid24807223.denovo.119, whole genome shotgun sequence.
ACCESSION   DBEJAU010000119 DBEJAU010000000
VERSION     DBEJAU010000119.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261939
            Sequence Read Archive: SRR26833919
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 681)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 681)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576303.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576303.1
            Genome Coverage       :: 154x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/19/2025 01:05:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,121
            CDSs (total)                      :: 2,078
            Genes (coding)                    :: 1,943
            CDSs (with protein)               :: 1,943
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 36
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 72 of 135
            Pseudo Genes (incomplete)         :: 63 of 135
            Pseudo Genes (internal stop)      :: 51 of 135
            Pseudo Genes (multiple problems)  :: 46 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..681
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261939-rid24807223.denovo.119"
                     /strain="GPSC323"
                     /isolate="683620"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            complement(293..681)
                     /locus_tag="ACL29Z_002103"
                     /pseudo
     CDS             complement(293..681)
                     /locus_tag="ACL29Z_002103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398172.1"
                     /note="internal stop; incomplete; missing N-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=3
                     /transl_table=11
                     /product="hypothetical protein"
BASE COUNT          233 a          120 c          105 g          223 t
ORIGIN      
        1 aggtgataaa gtccatcgtt aatcggagat ggactagaat gctttttgaa aacagatgag
       61 tattagaaat aaatgaaaag tcaatatcaa aacaatcaga atcttgatga tgctaaattc
      121 aaaaaaacta cataataatt ttaataaggg taagtcgtac caagaaaccc caccaagata
      181 aaaacttagt ggggtttggc ggggaatata attattctcc caattattat cgcctttata
      241 ttatctcaac tctcattaaa caagagttcc gcaatcaaat tgcgatactc tattatttaa
      301 aggtaatttg ggatttagcc tcatcaattg catcgtctaa tgacttatcc atggaaaaat
      361 cagataattt ctcaggatca ttcaccattt tttctaacag atggtctaaa tgattgtcta
      421 gaatcgaacg gtctttcgtg tagaaatgca gagaatcccc ttgccaagcg atggctaaag
      481 gaatctcttc tttttctaaa aaagctttaa atttctctat atcaattggt ttttctaaaa
      541 aatctttttt cagattaatc gtatcaatcg catagggaga ttgtagcaat tcttctaatt
      601 tctacacccc tatcttatag gcggaatcct gttctaaagc ctgacatcta gaccattcta
      661 gtatctttaa aagacctttt a
//
LOCUS       DBEJAU010000120          662 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC323 isolate 683620
            SAMN38261939-rid24807223.denovo.120, whole genome shotgun sequence.
ACCESSION   DBEJAU010000120 DBEJAU010000000
VERSION     DBEJAU010000120.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261939
            Sequence Read Archive: SRR26833919
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 662)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 662)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576303.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576303.1
            Genome Coverage       :: 154x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/19/2025 01:05:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,121
            CDSs (total)                      :: 2,078
            Genes (coding)                    :: 1,943
            CDSs (with protein)               :: 1,943
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 36
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 72 of 135
            Pseudo Genes (incomplete)         :: 63 of 135
            Pseudo Genes (internal stop)      :: 51 of 135
            Pseudo Genes (multiple problems)  :: 46 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..662
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261939-rid24807223.denovo.120"
                     /strain="GPSC323"
                     /isolate="683620"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            <1..582
                     /locus_tag="ACL29Z_002104"
     CDS             <1..582
                     /locus_tag="ACL29Z_002104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002837029.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HGR0070326.1"
                     /translation="NLSYKFTDDECLSLKDISFKLGKIYGIIGSNGRGKSTLLRCLIG
                     LEKKSKEEIYFKGEKLSKKERLKNSSLVMQDVNHQLFTDEVFNELRLGVKNFDEEKAK
                     IILKDLGLDEFIERHPMSLSGGQKQRLAIASVMCKNSPFVFFDEPSSGMDYSNMIKIS
                     ELINKYKTMDKIIFIVSHDIEFLNEVADEIFEL"
BASE COUNT          258 a           76 c          119 g          209 t
ORIGIN      
        1 aatcttagct acaaatttac tgatgatgag tgtttaagct taaaagatat ttcgttcaag
       61 cttgggaaaa tttatggcat aataggatcc aacggacgag gaaaatcaac gcttttaaga
      121 tgtttaatag gtcttgagaa aaaatcaaaa gaagaaattt attttaaggg agagaagcta
      181 tctaaaaaag aaagactcaa aaactcttca cttgttatgc aagatgtaaa tcatcaatta
      241 ttcacagatg aagtattcaa cgagcttaga ttaggagtaa agaattttga tgaagaaaag
      301 gcgaaaatca ttttaaaaga tttaggcctg gacgaattta ttgaaaggca tccgatgagt
      361 ttatcaggag ggcaaaagca aaggcttgca atagcatctg ttatgtgcaa gaattctcca
      421 tttgtctttt ttgacgaacc ttcaagtggt atggattatt ccaatatgat aaaaatatct
      481 gaactgatta ataagtataa aaccatggat aaaataattt ttattgtttc ccatgatata
      541 gaatttttaa atgaagtggc agatgaaatt tttgaattgt aaaatagagt ctgttaaaca
      601 tgtctataga actagtaaat tgtctaaaaa tttaaaagat actaacacat attgatattt
      661 at
//
LOCUS       DBEJAU010000121          645 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC323 isolate 683620
            SAMN38261939-rid24807223.denovo.121, whole genome shotgun sequence.
ACCESSION   DBEJAU010000121 DBEJAU010000000
VERSION     DBEJAU010000121.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261939
            Sequence Read Archive: SRR26833919
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 645)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 645)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576303.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576303.1
            Genome Coverage       :: 154x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/19/2025 01:05:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,121
            CDSs (total)                      :: 2,078
            Genes (coding)                    :: 1,943
            CDSs (with protein)               :: 1,943
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 36
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 72 of 135
            Pseudo Genes (incomplete)         :: 63 of 135
            Pseudo Genes (internal stop)      :: 51 of 135
            Pseudo Genes (multiple problems)  :: 46 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..645
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261939-rid24807223.denovo.121"
                     /strain="GPSC323"
                     /isolate="683620"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            93..389
                     /locus_tag="ACL29Z_002105"
     CDS             93..389
                     /locus_tag="ACL29Z_002105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000837727.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uberolysin/carnocyclin family circular
                     bacteriocin"
                     /protein_id="HGR0070327.1"
                     /translation="MKSKRMEFHNKFLIVSAMLAVISWLSLGVVSFPMLAGTLGISTK
                     AAATVVNLISAYSTVTAVISIVGAITGVGSIGSGIAATVLYILKKKGAAKAALW"
     gene            396..>645
                     /locus_tag="ACL29Z_002106"
     CDS             396..>645
                     /locus_tag="ACL29Z_002106"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000698829.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0070328.1"
                     /translation="MKILSKKECESILGYLNFIGITLLFFVIISLSIYFKSYLPFQGK
                     LFLLFLVVDYATLNRYNMKLPIQSKKINTFYIRKNYIFL"
BASE COUNT          219 a           82 c          111 g          233 t
ORIGIN      
        1 tatagacgaa catttgaaga gagttaggaa tacaacatgt gcgaattaac tctcaataaa
       61 acatacataa tatacaaaag gagtacacta aaatgaaatc taaaagaatg gaatttcata
      121 ataaatttct tattgtttca gcaatgttag cagtcattag ttggttaagc ttaggtgttg
      181 tttcttttcc tatgttggct gggacattag gaatttcgac aaaagctgct gctactgtag
      241 tcaatttgat tagtgcttat agtacagtta cagcagtaat ttcaattgta ggtgcaatca
      301 caggagtagg ttctattggt tcgggtattg cagcaacagt tctttatata ttgaaaaaga
      361 aaggtgctgc taaagcagct ctatggtaga actagatgaa aatactttct aaaaaagaat
      421 gtgaaagtat tttaggttat cttaatttta ttgggataac ccttttgttt tttgttatca
      481 taagtttgtc aatctatttt aaaagctatc ttccttttca agggaaatta tttttacttt
      541 ttttggtagt agattacgct actttgaatc gttataatat gaaactgcct atccaaagta
      601 aaaaaataaa tactttctat ataaggaaaa actatatttt tctct
//
LOCUS       DBEJAU010000122          634 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC323 isolate 683620
            SAMN38261939-rid24807223.denovo.122, whole genome shotgun sequence.
ACCESSION   DBEJAU010000122 DBEJAU010000000
VERSION     DBEJAU010000122.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261939
            Sequence Read Archive: SRR26833919
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 634)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 634)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576303.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576303.1
            Genome Coverage       :: 154x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/19/2025 01:05:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,121
            CDSs (total)                      :: 2,078
            Genes (coding)                    :: 1,943
            CDSs (with protein)               :: 1,943
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 36
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 72 of 135
            Pseudo Genes (incomplete)         :: 63 of 135
            Pseudo Genes (internal stop)      :: 51 of 135
            Pseudo Genes (multiple problems)  :: 46 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..634
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261939-rid24807223.denovo.122"
                     /strain="GPSC323"
                     /isolate="683620"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            complement(<1..579)
                     /locus_tag="ACL29Z_002107"
     CDS             complement(<1..579)
                     /locus_tag="ACL29Z_002107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622167.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HGR0070329.1"
                     /translation="MKIENESKSYDKCILKNISLEIDKGIYRVEGENGSGKSTLLQLL
                     AGLETFDSGLKNCVSKDVLYLDTNQLGVVPFTIEENLQLLCDSFQIHLSFEDKEQINT
                     FFDNKIGDNYMTASTGTKFKLGLSLIFAKNWDYIFIDETLSTVDARSIDMIAKRLISM
                     KESSTIIYVSHNLLNQELISKSQRILIEEGRVY"
BASE COUNT          221 a          113 c           73 g          227 t
ORIGIN      
        1 ataaacccgt ccttcctcta ttaaaatcct ttgagatttg ctaatcaatt cttgattcaa
       61 taaattatga gatacatata taatagtaga gctttctttc atggaaatta agcgtttagc
      121 aatcatatca atacttcttg catccactgt tgataaagtc tcatcaataa aaatataatc
      181 ccaattttta gcaaaaatta aggataagcc taatttgaat tttgttccag tagatgctgt
      241 catatagtta tctccgattt tattatcaaa aaaagtatta atttgttctt tatcctcaaa
      301 tgatagatgg atttgaaaag aatcacacaa caactgcaaa ttttcttcta tagtaaatgg
      361 aacaacccca agctgattgg tatcaaggta tagtacatct ttggagacac aattctttaa
      421 accactatca aaagtctcta gcccagctaa aagttgtaga agggtgctct ttcctgaacc
      481 attctctcct tcaactctgt aaattccctt atcaatctct agtgatatat ttttcaatat
      541 acatttatca taacttttag attcattttc aattttcata atttaattcc ctctatcaac
      601 gctgctaaaa ttaataaaag ataagaaatg atat
//
LOCUS       DBEJAU010000123          604 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC323 isolate 683620
            SAMN38261939-rid24807223.denovo.123, whole genome shotgun sequence.
ACCESSION   DBEJAU010000123 DBEJAU010000000
VERSION     DBEJAU010000123.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261939
            Sequence Read Archive: SRR26833919
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 604)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 604)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576303.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576303.1
            Genome Coverage       :: 154x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/19/2025 01:05:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,121
            CDSs (total)                      :: 2,078
            Genes (coding)                    :: 1,943
            CDSs (with protein)               :: 1,943
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 36
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 72 of 135
            Pseudo Genes (incomplete)         :: 63 of 135
            Pseudo Genes (internal stop)      :: 51 of 135
            Pseudo Genes (multiple problems)  :: 46 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..604
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261939-rid24807223.denovo.123"
                     /strain="GPSC323"
                     /isolate="683620"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            complement(21..500)
                     /locus_tag="ACL29Z_002108"
     CDS             complement(21..500)
                     /locus_tag="ACL29Z_002108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000588926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HGR0070330.1"
                     /translation="MIKELYEEVQGTVYKCRNEYYLHLWELSDWDQEGMLCLHELISR
                     EEGLVDDIPRLRKYFKTKFRNRILDYIRKQESQKRRYDKEPYEEVGEISHRISEGGLW
                     LDDYYLFHETLRDYRNKQSKEKQEELERVLSNERFRGRQRVLRDLRIVFKEFTIRTH"
BASE COUNT          159 a          142 c           81 g          222 t
ORIGIN      
        1 catttttttt gcatgacttc ctagtgggta cggatagtaa actccttaaa cacaatgcgt
       61 aagtctctta atactctttg acgccctcga aatcgttcat tgcttaagac gcgttctagt
      121 tcttcttgtt tctctttact ttgtttgttt ctataatctc ttagtgtttc atgaaagaga
      181 taataatcat ctagccagag acctccctca cttatacgat gactgatctc tcccacttct
      241 tcatagggtt ctttatcgta tctacgcttc tgactttcct gcttacggat atagtctaaa
      301 attcgatttc gaaacttggt tttgaaatat ttccttaaac gtggaatatc gtctaccagt
      361 ccttcttctc tactaatcaa ttcatgtaag cagagcatgc cttcttggtc ccaatccgac
      421 aattcccata aatgaaggta atattcattt ctacacttat acacagtccc ttggacttct
      481 tcatacaatt ctttaatcat aattttcccc tttctagata cagtctaaca gattagaaaa
      541 cacatttgtt ccattttctc cattctgttc cctttagctc ctaaactgca caaaaaagag
      601 aggc
//
LOCUS       DBEJAU010000124          595 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC323 isolate 683620
            SAMN38261939-rid24807223.denovo.124, whole genome shotgun sequence.
ACCESSION   DBEJAU010000124 DBEJAU010000000
VERSION     DBEJAU010000124.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261939
            Sequence Read Archive: SRR26833919
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 595)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 595)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576303.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576303.1
            Genome Coverage       :: 154x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/19/2025 01:05:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,121
            CDSs (total)                      :: 2,078
            Genes (coding)                    :: 1,943
            CDSs (with protein)               :: 1,943
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 36
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 72 of 135
            Pseudo Genes (incomplete)         :: 63 of 135
            Pseudo Genes (internal stop)      :: 51 of 135
            Pseudo Genes (multiple problems)  :: 46 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..595
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261939-rid24807223.denovo.124"
                     /strain="GPSC323"
                     /isolate="683620"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            231..>595
                     /locus_tag="ACL29Z_002109"
     CDS             231..>595
                     /locus_tag="ACL29Z_002109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000242196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HGR0070331.1"
                     /translation="MVLDYFFDKNLVFCLEADNQEQLFDQVASLLEEREIVTPTYREA
                     LITREKSFPTGLDMEFLGKDLPNVAIPHTDIVHNLAEKVVVVRLEKPVTFHNMIAPGK
                     EVEVSLLFFIINNSSSSQT"
BASE COUNT          207 a           90 c          113 g          185 t
ORIGIN      
        1 gtgttttgaa caacctgcgg ctagcttcct agtttgctct ttgattttca ttgagtatta
       61 gaacagaaaa atgcttggag tatttgtttg tgtgtttatt tttatataac aaactataaa
      121 caaaacaaaa atataaaaaa gagacaaaaa aagaacagaa agtaattaac aacgatttca
      181 tatagtgtta tacttatggc ataaagttaa tggaaagaag ggaaaacctt atggtattag
      241 attatttctt tgacaaaaac cttgtgtttt gcttagaagc ggataatcaa gaacaactct
      301 ttgatcaggt agcaagcttg ttggaagaac gagaaattgt cactcctact tatcgtgaag
      361 ccttgatcac gcgtgaaaag tcatttccaa ctggtttaga tatggaattt ctaggaaagg
      421 acttgccaaa tgtagcgatt cctcacacag atattgttca caatctggct gaaaaagttg
      481 tggtcgttcg attagagaaa ccggtgactt tccataatat gattgcgcca ggtaaggaag
      541 tagaagtatc cttgctcttc tttatcatca ataattcaag ttcaagtcaa acaaa
//
LOCUS       DBEJAU010000125          565 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC323 isolate 683620
            SAMN38261939-rid24807223.denovo.125, whole genome shotgun sequence.
ACCESSION   DBEJAU010000125 DBEJAU010000000
VERSION     DBEJAU010000125.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261939
            Sequence Read Archive: SRR26833919
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 565)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 565)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576303.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576303.1
            Genome Coverage       :: 154x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/19/2025 01:05:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,121
            CDSs (total)                      :: 2,078
            Genes (coding)                    :: 1,943
            CDSs (with protein)               :: 1,943
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 36
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 72 of 135
            Pseudo Genes (incomplete)         :: 63 of 135
            Pseudo Genes (internal stop)      :: 51 of 135
            Pseudo Genes (multiple problems)  :: 46 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..565
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261939-rid24807223.denovo.125"
                     /strain="GPSC323"
                     /isolate="683620"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            <1..472
                     /locus_tag="ACL29Z_002110"
     CDS             <1..472
                     /locus_tag="ACL29Z_002110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000239016.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="protein phosphatase 2C family protein"
                     /protein_id="HGR0070332.1"
                     /translation="LYYRLPIFAFIFAKLSEKKLEYMMLGDCVMLVNEMEITDHRVDN
                     LFEKGKNEIKDSIGTNSVLNKKIILQKIRKLSNQPSGYWIGSLDERFLDHAIINQIDV
                     TSEQIVLMSDGFYEFYQNNQNKTFEELIKMRFNSSAIDPIYGKKDDASILVIDV"
BASE COUNT          219 a           52 c           98 g          196 t
ORIGIN      
        1 actatattat cgcttaccaa tatttgcttt tatatttgct aaactttcag aaaaaaagtt
       61 ggagtatatg atgctaggtg actgcgtcat gttagtaaac gaaatggaaa taactgatca
      121 tagagtagat aacttatttg aaaaagggaa aaatgagata aaagattcaa ttggtacaaa
      181 tagtgtttta aataaaaaaa ttattttaca aaaaatcaga aaattatcta atcaaccgag
      241 tgggtactgg ataggttcgt tggatgagag atttttagac catgctatta ttaatcaaat
      301 agatgttact agtgaacaaa ttgttttaat gagcgatggc ttttatgaat tctatcaaaa
      361 taatcaaaat aaaacttttg aagagttaat taagatgaga tttaattctt ctgctattga
      421 tccaatctat ggaaagaagg atgatgcaag tattctagtc attgatgttt gatatattgt
      481 ttaaaatatt aattgttact attgaacttt gttaagaaga ggtacctaaa tgttaaggtt
      541 atatttagaa aatgaaatta tagaa
//
LOCUS       DBEJAU010000126          544 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC323 isolate 683620
            SAMN38261939-rid24807223.denovo.126, whole genome shotgun sequence.
ACCESSION   DBEJAU010000126 DBEJAU010000000
VERSION     DBEJAU010000126.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261939
            Sequence Read Archive: SRR26833919
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 544)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 544)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576303.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576303.1
            Genome Coverage       :: 154x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/19/2025 01:05:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,121
            CDSs (total)                      :: 2,078
            Genes (coding)                    :: 1,943
            CDSs (with protein)               :: 1,943
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 36
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 72 of 135
            Pseudo Genes (incomplete)         :: 63 of 135
            Pseudo Genes (internal stop)      :: 51 of 135
            Pseudo Genes (multiple problems)  :: 46 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..544
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261939-rid24807223.denovo.126"
                     /strain="GPSC323"
                     /isolate="683620"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            complement(71..196)
                     /locus_tag="ACL29Z_002111"
     CDS             complement(71..196)
                     /locus_tag="ACL29Z_002111"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000201422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0070333.1"
                     /translation="MATITNALNIAATVAEVFSLGGAIAYGLDIVDGKFDGYLWA"
BASE COUNT          208 a          100 c           61 g          175 t
ORIGIN      
        1 tggatataat aaaaataaca aaaaatgaat ttcaccaatt cctgcaaaaa aatgtttcat
       61 agctatagtt ttacgcccat aaatacccat caaatttacc gtctacgata tctaaaccat
      121 atgcaatggc tcctcctaat gagaagactt cagcaacagt agccgcaata ttaagagcat
      181 tagtaatagt tgccatacta actccaccaa tatatcttgt tatagcactt agttacctag
      241 ataagatatc ctttagcttg cttccaaaat ttaagtctgc acctataata tgagttcata
      301 ttagtactgc taaatcctat ctatagtaat gtcaaacacc taaataaagt catctctcca
      361 attcattcaa gaaatgaaga aaggcaaaaa atctttaaaa taagaaaaat gcatattatc
      421 aggtgttcaa aaatattgat gatatacgtt atatagatag aaagatttac tcaatctcat
      481 tttcaaattg agttttttcc caacctcgtt tttaatttat atcttcaata aaatctaatg
      541 acct
//
LOCUS       DBEJAU010000127          483 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC323 isolate 683620
            SAMN38261939-rid24807223.denovo.127, whole genome shotgun sequence.
ACCESSION   DBEJAU010000127 DBEJAU010000000
VERSION     DBEJAU010000127.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261939
            Sequence Read Archive: SRR26833919
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 483)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 483)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576303.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576303.1
            Genome Coverage       :: 154x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/19/2025 01:05:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,121
            CDSs (total)                      :: 2,078
            Genes (coding)                    :: 1,943
            CDSs (with protein)               :: 1,943
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 36
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 72 of 135
            Pseudo Genes (incomplete)         :: 63 of 135
            Pseudo Genes (internal stop)      :: 51 of 135
            Pseudo Genes (multiple problems)  :: 46 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..483
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261939-rid24807223.denovo.127"
                     /strain="GPSC323"
                     /isolate="683620"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            complement(<1..131)
                     /locus_tag="ACL29Z_002112"
     CDS             complement(<1..131)
                     /locus_tag="ACL29Z_002112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS630 family transposase"
                     /protein_id="HGR0070334.1"
                     /translation="MKSTKEEIQTIKTLLKDFRTAKYHKRLQIVLFRLMGKSYKEII"
BASE COUNT          151 a           74 c           75 g          183 t
ORIGIN      
        1 tctataatct ctttataaga tttgcccatc agacgaaata gaacgatttg aaggcgttta
       61 tgatatttag ctgtacgaaa gtcttttaaa agtgttttga tggtttggat ttcttcttta
      121 gttgatttca tattactatt gtataatgct ttttgatttg agtctagtat tatactcttc
      181 gaaaatctct tcaaaccgcg tcagcttcgc cttgtcgtat agatgttact gacttcgtca
      241 gttctatcta caacctaaaa acagtgtttt gagcagtctg cagctaactt tctataacaa
      301 aatgaaataa gaacaagaca aatcaatcaa gacaatcaaa tcgatttcta acaatgtttt
      361 agaagtagat gtgtactatt ctagtttcaa tatattatag tttgctcttt gattttcatt
      421 gagtattagt tcaatatcta aaaaaagagg ctctataata tttgtagtgg gtaaatcccc
      481 tat
//
LOCUS       DBEJAU010000128          445 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC323 isolate 683620
            SAMN38261939-rid24807223.denovo.129, whole genome shotgun sequence.
ACCESSION   DBEJAU010000128 DBEJAU010000000
VERSION     DBEJAU010000128.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261939
            Sequence Read Archive: SRR26833919
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 445)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 445)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576303.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576303.1
            Genome Coverage       :: 154x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/19/2025 01:05:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,121
            CDSs (total)                      :: 2,078
            Genes (coding)                    :: 1,943
            CDSs (with protein)               :: 1,943
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 36
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 72 of 135
            Pseudo Genes (incomplete)         :: 63 of 135
            Pseudo Genes (internal stop)      :: 51 of 135
            Pseudo Genes (multiple problems)  :: 46 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..445
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261939-rid24807223.denovo.129"
                     /strain="GPSC323"
                     /isolate="683620"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            315..>445
                     /locus_tag="ACL29Z_002113"
     CDS             315..>445
                     /locus_tag="ACL29Z_002113"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS630 family transposase"
                     /protein_id="HGR0070335.1"
                     /translation="MKSTKEEIQTIKTLLKDSRTAKYHKRLQIVLFRLMGKSYKEII"
BASE COUNT          153 a           84 c           65 g          143 t
ORIGIN      
        1 acaccaacaa gacgcttaaa tcgtgcatcg gttagttgtt tacttgcttc atcattcata
       61 gaactattat accatatttt gtttcgcagg aagtctattg aaaaatctcc agactggaga
      121 actcacggat agttcctaat ctggagattt cttatttgca cttttcttgt acaactttag
      181 tccatggtaa ataagcctct aaaacctctt tgtttacgag agtttcctcg tttggaagac
      241 attctagaag ataggataga tatttctcgc tatttatact agactcaaat caaaaagcat
      301 tatacaatag taatatgaaa tcaactaaag aagaaatcca aaccatcaaa acacttttaa
      361 aagactctcg tacagctaaa tatcataaac gccttcaaat cgttctattt cgtctgatgg
      421 gcaaatctta taaagagatt ataga
//
LOCUS       DBEJAU010000129          428 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC323 isolate 683620
            SAMN38261939-rid24807223.denovo.130, whole genome shotgun sequence.
ACCESSION   DBEJAU010000129 DBEJAU010000000
VERSION     DBEJAU010000129.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261939
            Sequence Read Archive: SRR26833919
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 428)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 428)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576303.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576303.1
            Genome Coverage       :: 154x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/19/2025 01:05:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,121
            CDSs (total)                      :: 2,078
            Genes (coding)                    :: 1,943
            CDSs (with protein)               :: 1,943
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 36
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 72 of 135
            Pseudo Genes (incomplete)         :: 63 of 135
            Pseudo Genes (internal stop)      :: 51 of 135
            Pseudo Genes (multiple problems)  :: 46 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..428
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261939-rid24807223.denovo.130"
                     /strain="GPSC323"
                     /isolate="683620"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            1..205
                     /locus_tag="ACL29Z_002114"
                     /pseudo
     CDS             1..205
                     /locus_tag="ACL29Z_002114"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001207345.1"
                     /note="frameshifted; incomplete; missing N-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=3
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
BASE COUNT          181 a           48 c           83 g          116 t
ORIGIN      
        1 ataaaccatt atggatacag ttagcaaaaa aagactaaag aaaacagatg taatagctat
       61 ggcaggactt acaacaaatg ttatggcaca aatgggaaag gataaaccaa ttacatttaa
      121 gaatttagaa agaatatgta aggctttatc ttgcactcct aatgatatta ttagttttga
      181 agataatttt agtgacgagg aatagaaaat gactttaagg acagaagatc aagttaggga
      241 ttatgcaaga gaagtatagg ctttaatgaa gttgaagaaa acatcaatca aggtactggt
      301 caaataacta cttttaatca attaggcttc aagggatatt cagataagcc agatggttgg
      361 tatttaccta aaaatatgaa tgatgtagca ataatccttg aaacaaaatc agaagaaaga
      421 gatattag
//
LOCUS       DBEJAU010000130          428 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC323 isolate 683620
            SAMN38261939-rid24807223.denovo.131, whole genome shotgun sequence.
ACCESSION   DBEJAU010000130 DBEJAU010000000
VERSION     DBEJAU010000130.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261939
            Sequence Read Archive: SRR26833919
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 428)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 428)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576303.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576303.1
            Genome Coverage       :: 154x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/19/2025 01:05:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,121
            CDSs (total)                      :: 2,078
            Genes (coding)                    :: 1,943
            CDSs (with protein)               :: 1,943
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 36
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 72 of 135
            Pseudo Genes (incomplete)         :: 63 of 135
            Pseudo Genes (internal stop)      :: 51 of 135
            Pseudo Genes (multiple problems)  :: 46 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..428
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261939-rid24807223.denovo.131"
                     /strain="GPSC323"
                     /isolate="683620"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            129..425
                     /locus_tag="ACL29Z_002115"
     CDS             129..425
                     /locus_tag="ACL29Z_002115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000239014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0070336.1"
                     /translation="MVKINKICSIQGSSVENEDIVGSQNQYFWIIGGATDLYNSKEEI
                     GYSVSEVVHILSESLSVNCKESKTLKQIFETALLEVKDEIGLNSYELTEYSKMK"
BASE COUNT          174 a           42 c           78 g          134 t
ORIGIN      
        1 taataaatct aaagaaatag tagatgtaaa acaaaaatta ccaaagactg gttcgaacaa
       61 gattatggaa ctattcttaa cagtgacagg aattggttta cttttgacac taaaagagtt
      121 gaagtattat ggtaaagata aataaaattt gttcgataca aggaagttcc gtagaaaatg
      181 aggatattgt aggttcacaa aatcagtatt tttggattat tggtggagct acagatttat
      241 ataattctaa agaggagata ggttattcag tctcagaagt tgtacatatt ttatcagaaa
      301 gtttgtcggt taattgtaaa gaatcaaaaa ctcttaaaca aatatttgaa actgctttac
      361 tcgaggttaa agatgaaatc ggtttaaact catatgaatt aacagagtat agtaaaatga
      421 aataataa
//
LOCUS       DBEJAU010000131          402 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC323 isolate 683620
            SAMN38261939-rid24807223.denovo.132, whole genome shotgun sequence.
ACCESSION   DBEJAU010000131 DBEJAU010000000
VERSION     DBEJAU010000131.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261939
            Sequence Read Archive: SRR26833919
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 402)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 402)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576303.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576303.1
            Genome Coverage       :: 154x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/19/2025 01:05:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,121
            CDSs (total)                      :: 2,078
            Genes (coding)                    :: 1,943
            CDSs (with protein)               :: 1,943
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 36
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 72 of 135
            Pseudo Genes (incomplete)         :: 63 of 135
            Pseudo Genes (internal stop)      :: 51 of 135
            Pseudo Genes (multiple problems)  :: 46 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..402
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261939-rid24807223.denovo.132"
                     /strain="GPSC323"
                     /isolate="683620"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            1..402
                     /locus_tag="ACL29Z_002116"
                     /pseudo
     CDS             1..402
                     /locus_tag="ACL29Z_002116"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000436408.1"
                     /note="frameshifted; incomplete; missing N-terminus and
                     C-terminus; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
BASE COUNT          121 a           81 c           73 g          127 t
ORIGIN      
        1 tctaaaattc cttatcttga aacgactggt atgcctacta gaattctcct tagaaagcgt
       61 cgtttcaagt gctatcactg ttcaaaaatg atggtcgctg aaacttctat cgtcaagaat
      121 aatcaccaaa tccctcgtat catcaaccaa aagattgctc aaaagttaat tgaaaagatt
      181 tctatgactg atattgccca tcagctttcc atctcaactt caactgttat tcgtaagctc
      241 aatgacttcc actttgagtg taattttaga aatctgcctg agattatgtc ttgggacgtt
      301 gaaacagtcc ggggagtgac tgtttcaatc gggagatgga gatgagcttc attgcgcaag
      361 attttaacaa tctcaatatc atcactgttc ttgagggtag aa
//
LOCUS       DBEJAU010000132          381 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC323 isolate 683620
            SAMN38261939-rid24807223.denovo.133, whole genome shotgun sequence.
ACCESSION   DBEJAU010000132 DBEJAU010000000
VERSION     DBEJAU010000132.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261939
            Sequence Read Archive: SRR26833919
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 381)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 381)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576303.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576303.1
            Genome Coverage       :: 154x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/19/2025 01:05:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,121
            CDSs (total)                      :: 2,078
            Genes (coding)                    :: 1,943
            CDSs (with protein)               :: 1,943
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 36
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 72 of 135
            Pseudo Genes (incomplete)         :: 63 of 135
            Pseudo Genes (internal stop)      :: 51 of 135
            Pseudo Genes (multiple problems)  :: 46 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..381
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261939-rid24807223.denovo.133"
                     /strain="GPSC323"
                     /isolate="683620"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            complement(27..116)
                     /locus_tag="ACL29Z_002117"
     tRNA            complement(27..116)
                     /locus_tag="ACL29Z_002117"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(78..80),aa:Ser,seq:tga)
     gene            complement(199..272)
                     /locus_tag="ACL29Z_002118"
     tRNA            complement(199..272)
                     /locus_tag="ACL29Z_002118"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(236..238),aa:Ile,seq:gat)
     gene            complement(307..377)
                     /locus_tag="ACL29Z_002119"
     tRNA            complement(307..377)
                     /locus_tag="ACL29Z_002119"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(343..345),aa:Gly,seq:tcc)
BASE COUNT          112 a          104 c           82 g           83 t
ORIGIN      
        1 gctgctccat cccgcgttaa tataaaagga ggatgtggga ttcgaaccca cgcacgcttt
       61 tacacgcctg acggttttca agaccgttcc cttcagccgg acttgggtaa tcctccaaaa
      121 tagtttatac gggaacaagc ccgtgtcctc ttagtgaaca gataatattc caatccccta
      181 gtaatggact aaacactatg ggcacgagtg gactcgaacc accgacctca cgcttatcag
      241 gcgtgcgctc taaccacctg agctacgcgc ccaagttaaa aacttggtac aaagaacaaa
      301 gttcaaagcg ggtgacgaga atcgaactcg cgacaacagc ttggaaggct gtagttttac
      361 cactaaacta cacccgctaa a
//
LOCUS       DBEJAU010000133          359 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC323 isolate 683620
            SAMN38261939-rid24807223.denovo.134, whole genome shotgun sequence.
ACCESSION   DBEJAU010000133 DBEJAU010000000
VERSION     DBEJAU010000133.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261939
            Sequence Read Archive: SRR26833919
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 359)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 359)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576303.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576303.1
            Genome Coverage       :: 154x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/19/2025 01:05:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,121
            CDSs (total)                      :: 2,078
            Genes (coding)                    :: 1,943
            CDSs (with protein)               :: 1,943
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 36
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 72 of 135
            Pseudo Genes (incomplete)         :: 63 of 135
            Pseudo Genes (internal stop)      :: 51 of 135
            Pseudo Genes (multiple problems)  :: 46 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..359
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261939-rid24807223.denovo.134"
                     /strain="GPSC323"
                     /isolate="683620"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            <1..>359
                     /locus_tag="ACL29Z_002120"
     CDS             <1..>359
                     /locus_tag="ACL29Z_002120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000639853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0070337.1"
                     /translation="FLNSLFKQDIPKTGIWTTSTYTATIDSESKYLGHKALKIIGLNP
                     SGRDGGNPKVTYPALGQFGKVIPGSTTNQDVTISFYAKANKNGIMLRSRLGNIGYKTG
                     NVTLSTEIKRYVVHIPKG"
BASE COUNT          126 a           60 c           75 g           98 t
ORIGIN      
        1 ttcttgaact cactattcaa gcaggatatt ccaaaaacag gaatttggac aacgagtaca
       61 tatacggcta ctatcgatag cgaaagtaag tatcttggac acaaggctct taaaattata
      121 ggtttgaatc catctggccg tgatggaggt aatcccaagg ttacttatcc agctctgggt
      181 caattcggga aagtaattcc cggaagtacg actaatcaag atgtaaccat tagtttttat
      241 gctaaggcaa ataaaaatgg aataatgcta agatctcgat tagggaatat cggatataaa
      301 actggaaatg tgacattgtc gacagaaatt aagcgatatg ttgtccatat tccaaaagg
//
LOCUS       DBEJAU010000134          353 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC323 isolate 683620
            SAMN38261939-rid24807223.denovo.135, whole genome shotgun sequence.
ACCESSION   DBEJAU010000134 DBEJAU010000000
VERSION     DBEJAU010000134.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261939
            Sequence Read Archive: SRR26833919
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 353)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 353)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576303.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576303.1
            Genome Coverage       :: 154x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/19/2025 01:05:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,121
            CDSs (total)                      :: 2,078
            Genes (coding)                    :: 1,943
            CDSs (with protein)               :: 1,943
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 36
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 72 of 135
            Pseudo Genes (incomplete)         :: 63 of 135
            Pseudo Genes (internal stop)      :: 51 of 135
            Pseudo Genes (multiple problems)  :: 46 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..353
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261939-rid24807223.denovo.135"
                     /strain="GPSC323"
                     /isolate="683620"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            1..353
                     /locus_tag="ACL29Z_002121"
                     /pseudo
     CDS             1..353
                     /locus_tag="ACL29Z_002121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="frameshifted; incomplete; missing N-terminus and
                     C-terminus; Derived by automated computational analysis
                     using gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /pseudo
                     /codon_start=3
                     /transl_table=11
                     /product="transposase"
BASE COUNT          127 a           65 c           72 g           89 t
ORIGIN      
        1 ttacgatttc aaaaactcat cttagtgctg aggatacggt gattgtggat gcaacagagg
       61 taaaaataaa tcgtcctaaa aaaatcaact agccaattat tctggtaaaa agaaatgcca
      121 cgctatgaag gctcaagcga ttgtcacaag tcaagggaga attgtttctt tggatatcac
      181 tgtgaactat tgccacgata tgaagttgtt caaaatgaat cgcagaaata tcggacaagc
      241 tggtaaaatc ttggctgaca gtggttatca agggctcatg aagatatatc ctcaagcaca
      301 aattccacgt aaatccagca aactcaagcc gctaatagct gaagataaag cct
//
